LOCUS       DAIGTA010000001        97864 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.001, whole genome shotgun sequence.
ACCESSION   DAIGTA010000001 DAIGTA010000000
VERSION     DAIGTA010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 97864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.001"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(176..2347)
                     /gene="copB"
                     /locus_tag="NOB43_000001"
     CDS             complement(176..2347)
                     /gene="copB"
                     /locus_tag="NOB43_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HCI0980916.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2367..4553)
                     /locus_tag="NOB43_000002"
     CDS             complement(2367..4553)
                     /locus_tag="NOB43_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HCI0980917.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4553..4762)
                     /gene="copZ"
                     /locus_tag="NOB43_000003"
     CDS             complement(4553..4762)
                     /gene="copZ"
                     /locus_tag="NOB43_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HCI0980918.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4775..5215)
                     /locus_tag="NOB43_000004"
     CDS             complement(4775..5215)
                     /locus_tag="NOB43_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HCI0980919.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5289..5828)
                     /locus_tag="NOB43_000005"
     CDS             complement(5289..5828)
                     /locus_tag="NOB43_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HCI0980920.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6443..7909)
                     /locus_tag="NOB43_000006"
     CDS             complement(6443..7909)
                     /locus_tag="NOB43_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0980921.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8220..10301)
                     /gene="cadA"
                     /locus_tag="NOB43_000007"
     CDS             complement(8220..10301)
                     /gene="cadA"
                     /locus_tag="NOB43_000007"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI0980922.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10825..11184)
                     /locus_tag="NOB43_000008"
     CDS             complement(10825..11184)
                     /locus_tag="NOB43_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCI0980923.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11214..11555)
                     /locus_tag="NOB43_000009"
     CDS             complement(11214..11555)
                     /locus_tag="NOB43_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980924.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(11552..12226)
                     /locus_tag="NOB43_000010"
     CDS             complement(11552..12226)
                     /locus_tag="NOB43_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0980925.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13279..14577)
                     /gene="asnS"
                     /locus_tag="NOB43_000011"
     CDS             complement(13279..14577)
                     /gene="asnS"
                     /locus_tag="NOB43_000011"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCI0980926.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14617..15807)
                     /locus_tag="NOB43_000012"
     CDS             complement(14617..15807)
                     /locus_tag="NOB43_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0980927.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15828..16355)
                     /locus_tag="NOB43_000013"
     CDS             complement(15828..16355)
                     /locus_tag="NOB43_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HCI0980928.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16402..19191)
                     /locus_tag="NOB43_000014"
     CDS             complement(16402..19191)
                     /locus_tag="NOB43_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI0980929.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(19338..19538)
                     /locus_tag="NOB43_000015"
     CDS             complement(19338..19538)
                     /locus_tag="NOB43_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0980930.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(19991..20311)
                     /locus_tag="NOB43_000016"
     CDS             complement(19991..20311)
                     /locus_tag="NOB43_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980931.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(20814..21932)
                     /locus_tag="NOB43_000017"
     CDS             complement(20814..21932)
                     /locus_tag="NOB43_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980932.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            22403..23710
                     /locus_tag="NOB43_000018"
     CDS             22403..23710
                     /locus_tag="NOB43_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCI0980933.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            23831..25030
                     /locus_tag="NOB43_000019"
     CDS             23831..25030
                     /locus_tag="NOB43_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI0980934.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(25057..26325)
                     /locus_tag="NOB43_000020"
     CDS             complement(25057..26325)
                     /locus_tag="NOB43_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HCI0980935.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLFYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPILQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(26489..27136)
                     /locus_tag="NOB43_000021"
     CDS             complement(26489..27136)
                     /locus_tag="NOB43_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HCI0980936.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(27545..28048)
                     /locus_tag="NOB43_000022"
     CDS             complement(27545..28048)
                     /locus_tag="NOB43_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0980937.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(28171..28935)
                     /locus_tag="NOB43_000023"
     CDS             complement(28171..28935)
                     /locus_tag="NOB43_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HCI0980938.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            29043..29318
                     /locus_tag="NOB43_000024"
     CDS             29043..29318
                     /locus_tag="NOB43_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCI0980939.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            29983..30933
                     /gene="yidC"
                     /locus_tag="NOB43_000025"
     CDS             29983..30933
                     /gene="yidC"
                     /locus_tag="NOB43_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI0980940.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            31037..32353
                     /locus_tag="NOB43_000026"
                     /pseudo
     CDS             31037..32353
                     /locus_tag="NOB43_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(33054..33254)
                     /locus_tag="NOB43_000027"
     CDS             complement(33054..33254)
                     /locus_tag="NOB43_000027"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980941.1"
                     /translation="MAEMHDHLLHSICERTGLSEEEVNQKLMEISEAMNKGVDFSMNQ
                     LDDFLAQHMKDALASDAADSVE"
     gene            complement(33604..33951)
                     /locus_tag="NOB43_000028"
     CDS             complement(33604..33951)
                     /locus_tag="NOB43_000028"
                     /inference="COORDINATES: protein motif:HMM:NF019886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0980942.1"
                     /translation="MDHLHDHDAENRLESNYARYLGGIEQTIEDSYTQDCMMSYTPDI
                     VEKIAPTDFKKMERKRLQEEIQKLTFNQRKVIEHYYFLNKNQQQIARDLRMSHAEITK
                     TLKRAFAVMKEVY"
     gene            complement(34346..34723)
                     /locus_tag="NOB43_000029"
     CDS             complement(34346..34723)
                     /locus_tag="NOB43_000029"
                     /inference="COORDINATES: protein motif:HMM:NF025104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980943.1"
                     /translation="MFFLAFLYLYIANVKYFSKWPLLLFWIISCVLLLVKNAVFQFLL
                     KKIGSKSHTRVLVVENGNLAKEYGLAMLSDPDADANIIGYVKDRKKEDILLEEPGFAN
                     YGDGLAKLKYFGRISDVQDVIVK"
     gene            complement(34747..35070)
                     /locus_tag="NOB43_000030"
     CDS             complement(34747..35070)
                     /locus_tag="NOB43_000030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980944.1"
                     /translation="MIDRRDDSDRCWSIRYYYKGRINEIIKERFWNTVFDCIGDAASI
                     FVAYLLAMFICYHVLEAAPGINMLSVPYLMMAALYSILIADFLRIFRATNKTYFRKYQ
                     NGFLK"
     gene            complement(35132..35608)
                     /locus_tag="NOB43_000031"
     CDS             complement(35132..35608)
                     /locus_tag="NOB43_000031"
                     /inference="COORDINATES: protein motif:HMM:TIGR01670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980945.1"
                     /translation="MSQIKFLVMDVDGTLTDGKIYMGECGEIMKAFNIKDGCAIHDIV
                     RAHNIEPIIITGRRSKILENRCKELGINILYQGIDNKIEKLLEITSDLSTVAYIGDDI
                     NDLSCMHPVKSAGGIVACPHDAVKKVLEISDFIAEHDGGNGAVREFVEWLVDTQNN"
     gene            complement(35625..35990)
                     /locus_tag="NOB43_000032"
     CDS             complement(35625..35990)
                     /locus_tag="NOB43_000032"
                     /inference="COORDINATES: protein motif:HMM:TIGR00022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCI0980946.1"
                     /translation="MELEEGRYDLSNGIYLNVESYDIYRFEERMYESHLKYLDIQCIL
                     LGCEYIVVESISNLQIEVDYSADKDIVFYSNSIVGNCVLLEGGKLLLLTPEDAHMPCI
                     RVNESAKVKKAVFKISINY"
     gene            complement(36073..37038)
                     /locus_tag="NOB43_000033"
     CDS             complement(36073..37038)
                     /locus_tag="NOB43_000033"
                     /inference="COORDINATES: protein motif:HMM:TIGR00393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HCI0980947.1"
                     /translation="MDKIIEAKRVFDIEIEALKRTRDCLGKTFVRILDAIVNCEGKVI
                     ITGMGKPGHIAAKLAATFASLGTPAFRLHPAEAMHGDLGMVSEKDIVIAISYSGESDE
                     IVKILPNIKMIGATLIGITGNSKSTLATASDIVQILPEFEEACYLGLAPTSSATSVLC
                     YGDALAVVASGIYGFKDSDFGKFHPAGSLGKKLILKVSDLMSHGNEIPMVNSGTLLMD
                     AISVMSNKGLGIVSVIDQDGTLKGIITDGDLRRIIERKVDIYSVEIDDVMIANPKVFT
                     KDKLAVDALRFLKANSINILPIIDDEGMLVGTITWQQIVKAGIVA"
     gene            complement(37147..37923)
                     /gene="kdsA"
                     /locus_tag="NOB43_000034"
     CDS             complement(37147..37923)
                     /gene="kdsA"
                     /locus_tag="NOB43_000034"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010388312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HCI0980948.1"
                     /translation="MNRLMLIAGPCVIESEENVMLIAKTIKEITEKLDIDYYFKASFD
                     KANRTSITSYRGPGIEEGLKILKKVKETYGLKICTDIHEPWQAEKAAEVCDILQIPAF
                     LCRQTDLLVAAAKTGKIINVKKAQFLAPWDMKNVINKLVEAGNSNIMLCERGTSFGYN
                     TLVVDMTSIVEMKKFGYPVVMDATHSVQKPGGKGDVTGGNRNNVEPLAKAAVATGADA
                     LFFEVHPDPDNALSDGPNMVLLDEFEGLLERVLKVYNAVR"
     gene            complement(37925..38662)
                     /gene="kdsB"
                     /locus_tag="NOB43_000035"
     CDS             complement(37925..38662)
                     /gene="kdsB"
                     /locus_tag="NOB43_000035"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: protein motif:HMM:NF003952.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HCI0980949.1"
                     /translation="MKTIAIIPSRYGSSRFPGKPLAMISSKPMIQWVYENVSKAAMLD
                     AVYVATDDKRIFDCVESFGGMALMTSDKHTCGTDRLAECAEILQLRDEDLVLNIQGDE
                     PLIKAEMIADLYSCFDNDEVYMGTLKKHIEVQEELDNPNVVKVINDVNDYAIYFSRFC
                     VPYERDGKNSLHFKHIGVYGYKTWFLKKYSTMPKTPLEVSESLEQLRVLESGFKIRVK
                     ETKYQTVGVDTPEQIQQVEDELRKEGL"
     gene            complement(38659..40086)
                     /locus_tag="NOB43_000036"
     CDS             complement(38659..40086)
                     /locus_tag="NOB43_000036"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024832.1,HMM:NF026018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HCI0980950.1"
                     /translation="MNRLIKNYAYNLCYQILVMILPIITTPYVSRVLKAEGVGEFNYS
                     YAIVSVAVIIAQLGTNMYGQREIAYVQNDKIRRSGVFWSIFVIRIISSFIVFPVYILI
                     SATLHSYTVLLISMSVYLVANLFDVSWFFQGMEDFKKTAIRSMVVKLIGLVLIFLLVK
                     NENDVVLYSVILAGTELLGNALLCCHIPKYVRRISIHDISITPHIRPILGLFLPTAAV
                     YIYTYVNKIILGIFSTDVQVGLYSQPEKIVKLLMTVITSLGAVMLPHIAVAVKENNID
                     RIRKEVLNAVSFVFCIGAPMVVGAIIIANTFIPWFLGDGYAKSVSLFQLLSPLILIIG
                     FASVVGQAVLIPMKRQRVYTFSIMTGAVINLVVNLALIPHLEAIGAAIGTIFAELTVT
                     AIQFYEVRNCIELKMASIITNVKNYLIGALIMGGVGGYVSSKLPNSVISTFITVILCI
                     LLYSILLICMKDKLLMDYLKRRKNR"
     gene            complement(40088..41401)
                     /locus_tag="NOB43_000037"
     CDS             complement(40088..41401)
                     /locus_tag="NOB43_000037"
                     /inference="COORDINATES: protein motif:HMM:TIGR04370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HCI0980951.1"
                     /translation="MIYQLLIVEFILILIMYILSNRCFISPAFIAIALFFLATCCVVY
                     NIEFWNVQYSKKTLWFITTGFLAMCIPEMYILFLDYLSKKRVDNYHQNQYKIEYVQIY
                     PSRQLNLIFALLSVVFFGVLLVEILRKGDYSTLGLYAIGAAKSDETQNSVIARFGISL
                     ITGLNLAYLYVFINNVIRCKERVLSNIKYLFPTLMYILCMFISGNRVFLVKLFAIVFL
                     IYIVMKSDVSPRGRVPVMQVVRKTLFVAVAILAVFYALRGITKVNSTAATREFSDYIT
                     YYIGSPVYMLDKYLQRYSPELNWGAKSLTSLVEMFGIEPEFKNAYIHVGGDSNFAGNE
                     FSWFQRPYSDFGWLGMLVFTFIVFWIFSWNIHIRINKEKNRRRRKYYILITAYFFYIP
                     VMSFYYCQMCFAFSITNIFSVVVACLLVREFTKRQDEIIFKIKEE"
     gene            complement(41402..42547)
                     /locus_tag="NOB43_000038"
     CDS             complement(41402..42547)
                     /locus_tag="NOB43_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HCI0980952.1"
                     /translation="MKKARVLAFYLPQFHPVRENDIMWGKGFTEWTNVAKAKPLFKNH
                     YQPQIPADLGFYDLRISEVRKQQAEMAKKYGVEGFCYWHYWFGNGKRILELPFNEVLQ
                     SGEPDFPFCLGWANHSWSNKTWQKSKHFTKDVVFLEQTYPGDEDYILHFKSILPALKD
                     DRYIKVDGKPLFLVFAPDSIPDSAHFISLWNKLAKENGFEGIYFVARVTSVDNKFDLS
                     SMTDVAVHNRFQRFLDMGYDAINSDMQRYAELKISGYWKRGIKSIMRKTVGNFSANLY
                     PYDKIMENFYCEEEKRECVHPQLIPRLDRTPRSGKDARVYVDSTPEKFGNAIDRALSY
                     VQDKEPEHRILFLQAWNEWGEGNYMEPDLVFGCEYLEILRKKILGEE"
     gene            complement(42544..43350)
                     /locus_tag="NOB43_000039"
     CDS             complement(42544..43350)
                     /locus_tag="NOB43_000039"
                     /inference="COORDINATES: protein motif:HMM:NF014075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF115 domain-containing protein"
                     /protein_id="HCI0980953.1"
                     /translation="MVNIKIRKVIHRIPPILKLMRFVVDVQNKYFYDKFCKNTDNIQR
                     IEKLRNKFLGETCFIVGNGPSLTMEDLELIKDKDCFAANLIFKIFDKTQWRPKYYFIQ
                     DRYADTGNELDDIDLEYMFIGDYYWRVRGMHNPNAICIHSEQSVGGKNIKFSEDISKS
                     IVSHETVTYSMIQAAVYMGYKKIYLLGMDHSYALTYNADGTVSEDKTIRSHFFEDKNA
                     NEVIASIVGMNQAYIRAREFCESNNIKIYNATRGGKLNWFDRITLEEAVK"
     gene            complement(43409..43597)
                     /locus_tag="NOB43_000040"
     CDS             complement(43409..43597)
                     /locus_tag="NOB43_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016396235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HCI0980954.1"
                     /translation="MVVKGTSDDFYHANDEGGLAWNDPEIGIEWPQVLGEYKGNASAE
                     GYIFEDDTPLNISEKGQR"
     gene            complement(43945..44079)
                     /locus_tag="NOB43_000041"
     CDS             complement(43945..44079)
                     /locus_tag="NOB43_000041"
                     /inference="COORDINATES: protein motif:HMM:NF013621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HCI0980955.1"
                     /translation="MKEKVIEYTTGVYDMFHIGHLNVMRNAKAQCDFLIVGVSTDEPV
                     "
     gene            complement(44420..45553)
                     /locus_tag="NOB43_000042"
     CDS             complement(44420..45553)
                     /locus_tag="NOB43_000042"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI0980956.1"
                     /translation="MRQKIRVLHIAQAAGGVDCYIRMLLKYLDKEKFENILICSQDFC
                     ETDYANLVLSFKQIKLTREIDLNDLKAIVIIRKLIKKYNPDIVYAHSSKAGAITRVAK
                     IGLKNYCVYNPHGWAFNMRCSVKKKMLYTAIEKIAALFCDKIICISDAEKQSALKKRI
                     CCEDKLQVIFNGVDIEAYRNKAHGEVKRESLNIPQDAFVVGMVGRISPQKAPEIFIKM
                     ARLVKNKIPEAHFIIVGNGEQKALIEKYAAEHGFLESLHITGWVNNSISYIELFDVAC
                     LLSRWEGFGLALPEYMMVGKPIIATNIDAIPNLISNGKNGLLVPVDDETAACEAVFKI
                     FSDKAMAARLTSEATSVVLEKYNSKRVASEHAVLFEMLVKKRG"
     gene            complement(45465..46017)
                     /locus_tag="NOB43_000043"
                     /pseudo
     CDS             complement(45465..46017)
                     /locus_tag="NOB43_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
     gene            complement(46486..47175)
                     /locus_tag="NOB43_000044"
     CDS             complement(46486..47175)
                     /locus_tag="NOB43_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI0980957.1"
                     /translation="MESEDLLSRISKVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYAAYRIRKEEPGSPIFFSHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTQIGKIIRAKSIDELPQLWNVLKGDMSLVGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSGRNDVSFHAMVDLDLEYITNQSLLNDFKLIIKT
                     IWIVIKPNGAY"
     gene            complement(47229..47993)
                     /locus_tag="NOB43_000045"
     CDS             complement(47229..47993)
                     /locus_tag="NOB43_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HCI0980958.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIVMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIQRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            complement(48021..48719)
                     /locus_tag="NOB43_000046"
     CDS             complement(48021..48719)
                     /locus_tag="NOB43_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HCI0980959.1"
                     /translation="MARTQKQKATPTHAVSLITLTNPSSPIAEQYRTIRTNIQFASTT
                     GQQIKTIVVTSSGPGEGKSTTASNIAVVFAKSGQRVLLVDADLRKPVIYKTFQLNNAS
                     GLSTALSSSGSVADVIQRAPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPIVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDDGYYYGN"
     gene            complement(48732..49511)
                     /locus_tag="NOB43_000047"
     CDS             complement(48732..49511)
                     /locus_tag="NOB43_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HCI0980960.1"
                     /translation="MEETISLEEIFETLRKHLITIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVQERLKTEDNVKMTP
                     EQIKDAISINQSENSQMFSIQAISTSAMTAQQIANTTSQVFQENAKDVMNVDKISIVS
                     GAVANTTPISPNNKLNLVIGLMLGMMVGVVLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSEKELKAGIRKKGLAPTRPKVTNDKTASSRRSRSRV"
     gene            complement(49527..50471)
                     /locus_tag="NOB43_000048"
     CDS             complement(49527..50471)
                     /locus_tag="NOB43_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0980961.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLNKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGVQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSILNALESNMKTDMSFDEMKKIALDYREAFDTIKQD
                     QMQGEGFMQDDISYQKVNDNELDRVKKELKEQMNLENK"
     gene            complement(50508..51284)
                     /locus_tag="NOB43_000049"
     CDS             complement(50508..51284)
                     /locus_tag="NOB43_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980962.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKIRAAYATKAQTVAQQMGYSNIS"
     gene            complement(51669..53744)
                     /locus_tag="NOB43_000050"
     CDS             complement(51669..53744)
                     /locus_tag="NOB43_000050"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCI0980963.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(53746..54663)
                     /gene="glyQ"
                     /locus_tag="NOB43_000051"
     CDS             complement(53746..54663)
                     /gene="glyQ"
                     /locus_tag="NOB43_000051"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCI0980964.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(55049..55861)
                     /gene="recO"
                     /locus_tag="NOB43_000052"
     CDS             complement(55049..55861)
                     /gene="recO"
                     /locus_tag="NOB43_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCI0980965.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            complement(56004..56903)
                     /gene="era"
                     /locus_tag="NOB43_000053"
     CDS             complement(56004..56903)
                     /gene="era"
                     /locus_tag="NOB43_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCI0980966.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(56918..57313)
                     /locus_tag="NOB43_000054"
     CDS             complement(56918..57313)
                     /locus_tag="NOB43_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HCI0980967.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            complement(57297..57773)
                     /gene="ybeY"
                     /locus_tag="NOB43_000055"
     CDS             complement(57297..57773)
                     /gene="ybeY"
                     /locus_tag="NOB43_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCI0980968.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(57790..59982)
                     /locus_tag="NOB43_000056"
     CDS             complement(57790..59982)
                     /locus_tag="NOB43_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HCI0980969.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(60006..60977)
                     /locus_tag="NOB43_000057"
     CDS             complement(60006..60977)
                     /locus_tag="NOB43_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCI0980970.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            61683..63062
                     /gene="brnQ"
                     /locus_tag="NOB43_000058"
     CDS             61683..63062
                     /gene="brnQ"
                     /locus_tag="NOB43_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI0980971.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(63218..63664)
                     /locus_tag="NOB43_000059"
     CDS             complement(63218..63664)
                     /locus_tag="NOB43_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HCI0980972.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(63691..63867)
                     /locus_tag="NOB43_000060"
     CDS             complement(63691..63867)
                     /locus_tag="NOB43_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCI0980973.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(64029..64457)
                     /locus_tag="NOB43_000061"
     CDS             complement(64029..64457)
                     /locus_tag="NOB43_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0980974.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            64549..65409
                     /locus_tag="NOB43_000062"
     CDS             64549..65409
                     /locus_tag="NOB43_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HCI0980975.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(65503..65853)
                     /locus_tag="NOB43_000063"
     CDS             complement(65503..65853)
                     /locus_tag="NOB43_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI0980976.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(65869..67596)
                     /locus_tag="NOB43_000064"
     CDS             complement(65869..67596)
                     /locus_tag="NOB43_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCI0980977.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(67810..68736)
                     /gene="trxB"
                     /locus_tag="NOB43_000065"
     CDS             complement(67810..68736)
                     /gene="trxB"
                     /locus_tag="NOB43_000065"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCI0980978.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(68881..70317)
                     /locus_tag="NOB43_000066"
     CDS             complement(68881..70317)
                     /locus_tag="NOB43_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0980979.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     ENEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(70314..71717)
                     /locus_tag="NOB43_000067"
     CDS             complement(70314..71717)
                     /locus_tag="NOB43_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0980980.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            71947..72849
                     /locus_tag="NOB43_000068"
     CDS             71947..72849
                     /locus_tag="NOB43_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0980981.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(72890..74776)
                     /locus_tag="NOB43_000069"
     CDS             complement(72890..74776)
                     /locus_tag="NOB43_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0980982.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(74873..75724)
                     /locus_tag="NOB43_000070"
     CDS             complement(74873..75724)
                     /locus_tag="NOB43_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0980983.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(76047..77831)
                     /locus_tag="NOB43_000071"
     CDS             complement(76047..77831)
                     /locus_tag="NOB43_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0980984.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(77831..79582)
                     /locus_tag="NOB43_000072"
     CDS             complement(77831..79582)
                     /locus_tag="NOB43_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0980985.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            complement(79724..79948)
                     /locus_tag="NOB43_000073"
     CDS             complement(79724..79948)
                     /locus_tag="NOB43_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HCI0980986.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            80199..81785
                     /locus_tag="NOB43_000074"
     CDS             80199..81785
                     /locus_tag="NOB43_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCI0980987.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            complement(82094..83869)
                     /locus_tag="NOB43_000075"
     CDS             complement(82094..83869)
                     /locus_tag="NOB43_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HCI0980988.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(84080..84982)
                     /locus_tag="NOB43_000076"
     CDS             complement(84080..84982)
                     /locus_tag="NOB43_000076"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCI0980989.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            85261..87606
                     /locus_tag="NOB43_000077"
     CDS             85261..87606
                     /locus_tag="NOB43_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI0980990.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            complement(87769..88035)
                     /locus_tag="NOB43_000078"
     CDS             complement(87769..88035)
                     /locus_tag="NOB43_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980991.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(88028..88351)
                     /locus_tag="NOB43_000079"
     CDS             complement(88028..88351)
                     /locus_tag="NOB43_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980992.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            complement(88363..89619)
                     /locus_tag="NOB43_000080"
     CDS             complement(88363..89619)
                     /locus_tag="NOB43_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HCI0980993.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            complement(89616..90011)
                     /locus_tag="NOB43_000081"
     CDS             complement(89616..90011)
                     /locus_tag="NOB43_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0980994.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            complement(90365..91366)
                     /gene="ccpA"
                     /locus_tag="NOB43_000082"
     CDS             complement(90365..91366)
                     /gene="ccpA"
                     /locus_tag="NOB43_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HCI0980995.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            91576..92679
                     /locus_tag="NOB43_000083"
     CDS             91576..92679
                     /locus_tag="NOB43_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI0980996.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            complement(92742..93356)
                     /locus_tag="NOB43_000084"
     CDS             complement(92742..93356)
                     /locus_tag="NOB43_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI0980997.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(93349..93798)
                     /locus_tag="NOB43_000085"
     CDS             complement(93349..93798)
                     /locus_tag="NOB43_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HCI0980998.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            complement(93923..94861)
                     /gene="galU"
                     /locus_tag="NOB43_000086"
     CDS             complement(93923..94861)
                     /gene="galU"
                     /locus_tag="NOB43_000086"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI0980999.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            complement(94876..95901)
                     /locus_tag="NOB43_000087"
     CDS             complement(94876..95901)
                     /locus_tag="NOB43_000087"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI0981000.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            complement(95945..96775)
                     /locus_tag="NOB43_000088"
     CDS             complement(95945..96775)
                     /locus_tag="NOB43_000088"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCI0981001.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            complement(96790..97728)
                     /locus_tag="NOB43_000089"
     CDS             complement(96790..97728)
                     /locus_tag="NOB43_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HCI0981002.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
BASE COUNT        28050 a        20978 c        16898 g        31938 t
ORIGIN      
        1 gagtatccta cggatttaaa tcatttgaga acatgagaat tagaatcttt ttgatcaatc
       61 aattaatcaa agtaagataa caaaaaatct gagccagaat gaggttcatt ctgacccaga
      121 tttgattttg tacaacccat cagtccttat tgacaaagag cccctttttt cattattatt
      181 tgattttcaa tgtcaaagca tttagagcta caactaccgt acttaacgac atcaagacag
      241 caccaactgc tggacttaat atgataccaa ttggcgcaag aattccggct gctagcggaa
      301 ttgcaagaat attgtaacct gccccccacc agaggttctg gatcattttc tttcgcgttt
      361 gcttggctag atcaagaaaa tgcaaaatat cttttggatc gctgtttgtc aatacgacat
      421 ccgcagaatc gattgcgata tctgtccctg caccgattgc catcccgatt gaagcacggg
      481 ctaaacttgg cgcatcattg atcccatcac ccaccatgat tacttttttc ccttggtcaa
      541 ggtatttctg gacaacagct tctttatcat ctggtaataa accgccataa tattcttcga
      601 tccctaaata atctgctact gcttgggcag cgtttttatt gtcaccagta agcatgacag
      661 gagtgatttt tctttctttc aatgttcgga taaattcttt tgcttctgtt tttactacgt
      721 cacctaaagc aacgattgca gctagatgat tttctaaaat caggaagctg atggtatttc
      781 cttgttcttg gtaaggtttc aataatgctt gttctacgtt taatccgaga cgctcaactt
      841 ctttttcatt aactattttc acttgttgtt ttttgactgt tgcctctagc ccgactcctg
      901 aaagattttt tagattttca gcttgataag gcttgatttc atgttctttc aaataattca
      961 taatgccaac agccaatgga tgattggcat tcgcttccaa ggctcctaga tattgaagga
     1021 tttcattttt attgaacgca tcatcaagta cttcgacacc cgttacagta aattttcctt
     1081 ctgttagtgt tcctgttttg tccagcatga tcacatctag atcattggct tgctccagtg
     1141 cattgcggtt tttcaaaagt aatccgtttt tagctgctat tgatgtggag cgagcaacaa
     1201 ctaatgggat agctaaacct agagcatgag gacaggcgat gataaagact gttaccatac
     1261 gttctaatgc attaggaaga tctgtcaaga acaaccaggc gatgaatgcc aggataccca
     1321 caattaatgc gacataaaac agccattttg ccactttgtc agataatgac tctagcttgg
     1381 atttttctcc ttgtgctttt cgcaccattt ccataacctt cgctagataa ccattttcac
     1441 cagttccagt tacttcgatt tcgatcgttc catccccatt gatagaaccg ccaatcactt
     1501 tgtcattggc ttgttttttg attcctcttg attcgccagt cacagctgat tcgtcaacaa
     1561 ttgtttcacc tttcaagatt acaccatctg ttggcatttt atcaccagac cggacgatca
     1621 aacgatcacc ttcgtttact tctttcaatg aaactgtctc ttcttttcca tctttcgtca
     1681 agcgtttcac tgattctggc agtaattctg ctagtttttg taaagcattg ctggcattcg
     1741 acacagcatt catttcaatc cagtgaccta gtagcataat aacgatcaaa gtagccaatt
     1801 cccagaagaa atccatgacg tgtgtatgtg gattgagcag atttgcgata aacgaataga
     1861 cactataaat atatgcaact gtaatcccca tcgcgatcag tgtcatcata gcaggacttt
     1921 tttgtttcaa ttccatctta gctccactta aaaatggctg accgccatag ataaatagta
     1981 tagttgctaa gatcaatacg agccaatcag aaccaggaaa cgttacttga aatggaaatt
     2041 ccattcccat cattggtgaa aaaagaatga ttgggatagc taggataagc gatagccaaa
     2101 atttttgttt gaaattcccc atgtgcatgg aatgatccat gccgccgtgt tcgtgatcca
     2161 tgtgcatcga atggtccatt tgtttgctgt ttgctatatc tccatggtta tgtcccatgt
     2221 gcatggaatg atccatctga ctatggtcat gtttcatctc catctgtttt tcatgagatt
     2281 ctgtactttc tttgtttact acttcttttt tatgctcatg ttttttctcc atatcgttcc
     2341 cattcatttt tactccatcc cttctcttac tttttcatgt gtcgatttaa gctcagggag
     2401 ttcaacaata cactgacgga actaaacgcc atcgctcctc ctgcaatgat tggattcaaa
     2461 aagcctagtg cggcaaaagg aataccaatc gtattataga caaaagccca gaaaagattt
     2521 tgtttgattt ttctcaatgt caacctagac aactcgattg tttgtgcaat ggatgccaaa
     2581 ctgctattca tcagcgtcac atcggctgtt tccatcgcaa tgtccgttcc acttcccatt
     2641 gccataccga catcagctaa tgctaaggcc ggtgcatcat tgattccatc gcctgccata
     2701 ccgacttttt tgccatcttt ctgaagtttt tctacgtagg ctgctttatc ctctggaagt
     2761 acttcagcaa agatatgctt tggatcaata ccaacttgtt taccaatcgt ttcggctgcc
     2821 agtttgttgt ctcctgtcag cataaaaaca tctaatcctt tattctggag ctgcttgatt
     2881 gcttgtttgg cttctagttt gatttgatca gccacggcaa tccacccgat cacttgcttt
     2941 tcatcagcta aaaacatgac tgtttttccc tgctgttcta attctaacgc gtgttcttgg
     3001 tattcatcaa atgataggtt caattcaatt aatcgtttac gtgtacccgc aaaatagcgt
     3061 actccattaa tcgtaccgct gatcccagca cctgggtggg ctgtaaaatc aatcatatcg
     3121 tatgttgctg cttcttgcag ttttccgtat tccacgattg ctttacctag tggatgttca
     3181 gaagcttgtt ctaaagtata aaaaatagat aggacttctt ttgaaccgac tagatctgta
     3241 actttgggct ttccttctgt aatcgttcca gttttatcca aaacaatgct gtctaagtga
     3301 gcagctgctt ctaatgcttc tccgccttta attaaaattc catttcgtgc accaacaccc
     3361 gttcctacca taatagctgt tggggtcgct aaacctaatg cacatggaca cgcaatgact
     3421 aatacagaga cactatggat caatgcgagt tgccaatcac cagtgatcaa acctgtagct
     3481 atgagcgtga taaacgcgat gactaatacg atcggaacaa aaatccctga gatccgatct
     3541 gcgatttttt ggattggggc tttgctccct tgagcatctt ccaccatttg aatgatttgc
     3601 gctaatactg tctgcttgcc gacttgtgtg acttccatgt gtagcagacc attcgtattg
     3661 attgtcccgc caaaaagcgt gtcatccgga ttcttttcta caggaagatt ttcaccagta
     3721 agcatacttt catctatcgc actgcttcct gaaataattc gaccatctgc tggaatctgc
     3781 tcaccaggac ggatgactag ttgatcacca acgactactt cttcaatcgc taacgtttct
     3841 tctttcccgt ttcttatcac ttgggcggtt tttgtttgaa gagacatcaa ttgtttgatt
     3901 gcattacctg ttttcgtttt tgctgtatgt tccaaatatt tgccgagcaa aatcagcgtg
     3961 atgatcatac tgctgctttc aaaataaaga tcttgggggt gtccacggaa aaatccgttg
     4021 taaatgctca atgcaaaggc agccgatgtt ccaattgcta ccaatacatc catatttggt
     4081 gctttcgtct tgattgcatg gtacgcacct ttataaaaac gagcaccgac ataaaattgg
     4141 acaggagcag acagcactaa ctggacgatt ggaaaatgaa aaaagtgaac aatcgccgca
     4201 tggcttccta acatcatagc aatcattgac aacatcaacg gcaaagtcaa aaccgtactc
     4261 aatataagat cgaatagcat ttttttcaaa tacgcttgct tttcttctgc aattttttgt
     4321 ttgtgggctt catcgtacaa aattgcacca taaccgatgt tttctacgct ttggattaat
     4381 ttttcagtgg tcgtcccttc atatttgaca cttgcttttt cagtggccaa gttgactgtg
     4441 gcattgacca caccaggttg tccgttcagc tctttttcga tcctagcaga acaatttgca
     4501 caagtcatac ctgtaatgac gaacgtatcc attttggttt ctgctgttgc catcaaatca
     4561 cctctgcttt ataacccaat ccattgattg cttgacaaat cttttcggat tgaacttttg
     4621 tttcatcaaa cttgaccgta ccgtttgctt ttttcaaatt tactttcact ttttgcacgc
     4681 cgtcaagtgc gcttactgtt tcttctactc ttgctgcaca atgattgcag ctcatacctt
     4741 cgattgaaaa ttgttgtttc attttttctt cctcctattg atgttgttta cattcacatt
     4801 gacctgggat acagttacat tcgatcgtat ctactggttg cttttgttcc agttgtttca
     4861 aaatctcatt gatatcttct tgagtcaaag tggcttcttc tactagatcc gcaatcgtct
     4921 ctccaatcct ttttgcacag atatgggaaa aaagattttc cgtcgcactg cgaactgttt
     4981 ccatctccga gacagctgga tgataaatga atttttttcc ttcttgttct gtccagatca
     5041 cttctttttt taccaaacgt cccagcaaag ttttgatcgt tgctggtttc caatccatcg
     5101 aatcagctaa gatctgcgtg atttcttggg ctgtcgtctg tccaagtgtc caaataacac
     5161 gcatgatctc ccactctgaa tcactgatct ttactggcgt tttgactttt tccatttatt
     5221 tcacaccttt cgtttacaaa tgtaatcatt agcttatgaa tacagattac gcttgtaaac
     5281 aaaaactgtc aattattttt gctctctatt ttcaatttag ttaaaaattc ttgtttctct
     5341 cgtcttgttt taaggatgat cagtttattt cttgcattag ctacttggat cagctgctgt
     5401 attttcggtt cattgttttc ttcaaaatgc cagataaaag ataaaaattc taagtattcc
     5461 ctgtttagtt tctctgaaaa tgattcaggc atatctggcc gagatttttt gtttatcttt
     5521 ctttttagag aacgccaaac tactcggtag atggcgagat aacgcggcac tttaagccaa
     5581 atgatcttat ctgcttcttt aatcctttcc tctaatgtag aagtataatt tccttcaaca
     5641 atccatgacg gattagatac cataaacgat tgctgttctt gcaaaaacca cttttttgcc
     5701 tgaatactgt agtctgttgt atgccataaa aggtctagcg gcagtagcgg aaagtcggtg
     5761 atttctttga tcttccttgc gagggtcgat tttcccgacc cactttgtcc aatcacgatg
     5821 atcttcattc ttctccctca cttctctttg gaatttggtt cgatcatacc acttataacg
     5881 ccgcaaaaaa acaagggact gtgacaaaag tcgtgtcaaa gtcccttgtt tcgaataaat
     5941 ggtgttcaat cagctgacct tcagcattaa ctcaaaaaac ggcaaaatat gaggagctat
     6001 tttttcgttt gttcctctaa tactcaggtc aaatcgctga ttttacaacc tcttccttaa
     6061 acggtgttct cctgccaaca cctcggtcac aaggcacaat agtcaacaaa catgagaagt
     6121 tgttttttga aattgctcct tgtgactcgg agttaaacgg caggctcact acctctttct
     6181 taaacggtgt tcaaaagctt gcatctgcgg taataagccc agcaaaacga aaaatatgag
     6241 gggctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct
     6301 gattcacggt gttccagaag tagcttctgc gaaaaacaag ccgaaacttc acaaaaattt
     6361 gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc
     6421 tcttgtaaca agtatttcta ttttaaggct gaaccactgt ttctggttca gtgatttctt
     6481 tgtttttgtc tcgacgagca attgctggca agatcatacc taataagatc aagacaattg
     6541 gtgtgatgat attcgtgaat aattggaacc accatgcttt aggatcagca gtataatcta
     6601 cttttggcac cattcctagg atacatgcaa acgcagtgaa ggcaaagcac caagcaccaa
     6661 agataaaacc gatttttgga tttttaacaa atttatattc agaattgaat ttcttataag
     6721 ctttattcaa catcatatat gccaagaaca cccataggta acgcattggc atgacaactg
     6781 agttcaagtt cgtcaaccat tttactaatt cattcatatc tttgatacca aagatcggca
     6841 acaaaataat gattcctact agtatacctg tcagaagata accattcacc aatgtacctt
     6901 tacgattacg tttacgtagc cagtttggta caaattctgg atccgcatct gctaacaaga
     6961 tttttagtgg tgcatcaatt gaaaaggcta atgcggagat ttgtccaatc atgtttgtca
     7021 atgcgtaaat gatcatcaat gagttaccga taccatagta attacctaaa atttgaaaag
     7081 cactgtatgc cccatttgcc atcaagtctt taggaatatt atcgctagca aacagcatac
     7141 ccattgcgac tgagcctaat acagcacaaa tccctaccat tgctgctaag aagatcatcc
     7201 ctttaggaaa ttcctttgca ggatttcttg tagagttgac ataaggggat attttttccg
     7261 ctcctccaac tgcaaatact agcatcgaaa cggttgtgaa ataactgaaa tcaaatgttg
     7321 gaatatatgt tttcacttga ttcatatgtg gtgtggcaaa ttccatcgtt ggattgatga
     7381 acggtgccgt tacagctaaa agaataaata agatcgacat gacgaacatc gctgttccgg
     7441 ccagtccgcc aatcactttc aaagtagaaa gtccttttgt tgataaatat aaaaaggcaa
     7501 gaaatataat aagtgaaata actgctacca tttgtactga catcgtattt acgatatttc
     7561 catttccttg gactgcccaa ccgccagcaa tcaggattgc ttgaggcttt tgtgccaaat
     7621 aaggaatatg gacgacccag taagtccaag cggcatagta tgccagtcgt ttattagatg
     7681 tcgtattttc gacccatgaa ctgacgcctc ctttactatc cttgaaggct gaccctaatt
     7741 gtccaacgat caatgcgtat ggaataaaat aaatggccaa aatcaatagc caagaggtga
     7801 caactgatac tccttgctga gcatagttat taactacatt ccccatgccc caaaccatgt
     7861 taaatgcaat taacgcaaca gtaaaccagc gtaattgttt gttgttcatt cgttctctcc
     7921 tttatgataa aaatttgtta tccagatgta atcatattca atttttaaca aacttacaag
     7981 acagtgttat tttatgtgtg tattctttta tttaatacac atcgtttttt catatttttt
     8041 ccatcaaaaa aataagttat tttcttttat ttcatttacc ttattgaatt tcaagctatt
     8101 ttgaattttc tgcaaaatta aaaacattag ttattttata atcctatcta ttttctttac
     8161 atttttcatt aagaaaagga tataaaaaaa agaggacgtt cattcgtcct cttcattgat
     8221 caacgtttat tttttacatg caagcttcgc atggcattca aaacagctaa tactgtcacc
     8281 ccaacatctg caaatactgc atctcccatt gatgcaaaac caaaagcacc taaggcaagt
     8341 accaaaattt ttatcccaat agcaaagaca atgttctgtt tgacgatttt caatgttttc
     8401 tttgctaaat ggattgcttc tgcaatcttc gatggttgat cattcatgat gactacatct
     8461 gctgcttcaa ttgcagcatc gcttcccaat ccacccattg cgattcctac atctgctctt
     8521 gctagcaccg gtgcatcgtt gattccatct ccgacaaatg cggtcttttt attgtttctt
     8581 tgtaagattt cctctaaccg ctgcacttta tcttctggaa gcaattcgct atatatcttg
     8641 tccacgccta cttgcttccc gatatgatca gcaatttttt tcgaatcgcc cgtcaacatg
     8701 actgtgttct tcacaccagc cttttttaat tgaaccaatg cgtctacggc atcttctttc
     8761 aaggtatctg caataacaag ataaccactg taactttgat cgatcgctag ataaagcaat
     8821 gtaccgattt cttgacttga aggaaaagag atttcaaatc tttccatcaa tttgtgatta
     8881 cctgctaata cttgtttgcc atcaacttca gctaagatcc cttcacctgc aaattcttgg
     8941 atattagctg ttggtaaaag cggacctgcg tagccttcta aaacagattg agcaatcgga
     9001 tgtgtagaaa actgttctgc actcgcaaca tattgcatga atatctttgg atcgattttt
     9061 gtatcgatcg tctggatcga aaagtcacct ttcgttaatg tgccggtttt atcgaatacc
     9121 actgtctcag tttgtgcaag caactccaag taatttgaac cttttactaa tacaccgatt
     9181 ttacttgctc ctccgatacc gccaaagaaa ctaaggggta cggagatcac taatgcacat
     9241 ggacatgaga tcactaaaaa tgtcaatgct cgatagatcc attcagaaaa cgccgctcca
     9301 gaaacaacaa gtggaggtaa aacagctaat aaaacggcca atcctacaac gactggtgtg
     9361 taatagcgcg cgaatttagt aatgaaattt tcagctggtg cttttttact gctggcattt
     9421 tctactaatt ctaataattt gctgatagta gaattttcat aagatttttc tacttgaact
     9481 aaaaatggtt tatttttatt gataaatcca cttaatactg tttcaccaac atatacagat
     9541 ttagggactg attctcctgt aagtgctgac gtatcgacta atgattctcc ttcgatgatc
     9601 gttccatcta acggtacacg ttcaccaggc ttcacaagta caaactgacc gatctgcacg
     9661 tcttcagggt tcacggtcat caatccttcc gtcgtctgca cgtgagctgt ttctggacgg
     9721 atcgccatca attcgcgaat cgattttctt gaatgactga ctgccaatcc ttggaaatac
     9781 tcgccgattt gataaaatag catcactgct acggcttctg gatattcacc gatcaacata
     9841 gcgccaatcg tagcaacaga cataagaaaa ttctcatcaa agatttttcc tttgacgata
     9901 ttcatcactg ccttcttcac tacatcatat cctatcagca gataaatcaa taaataccct
     9961 atcaagcgaa ttggttcatt aaaatcaaat aatagcaata aagcgatacc tgcaagggaa
    10021 aataaaatcc ggaacagcgt atttctctct ttttcatttc catgttcaga tactttttcc
    10081 ttatctattt ctgttacttt gacatctggt tctaattcct tcactacttt ttttatttct
    10141 tgttcaatcg tagccaaatg atcttcctct gcgtcaatcg ttagttttcc agaagtgaag
    10201 tttaccgttg cttccttgac tccattgatc ttctgaactc ctttttcgat tttcattgca
    10261 cagttcgcac aatctaaacc ttctaatctg taacttttca ttttaatgac ctcctcgcct
    10321 caacatatga atatctcttc ataactaatt ataaatgaac ggttattcat atgtcaaggt
    10381 atccgaaaga aaaaatgaaa aacatctgca tcggaaaatt tcttccatac agatgttttg
    10441 gcttattctt tctttttctt ttcgatcatt gccactgctc ttatccaacc cgcacttgcc
    10501 ttcttgatct tgacaggata gcaactaagt ttgaagcctg ttgctggcaa tttgtctaaa
    10561 ttcattaatt tttcgatagg acaatatctt ttttcaatcc ctgcaaaatg tccttcccag
    10621 atattcgaag ctccactacg ctttcaaaaa tatagaaaga gttctttaat gaaaattatt
    10681 tcaactttcc ataaacagta accccatata aataaaagac gtaaaagtca catggaagaa
    10741 cttatacagg agaacgcata gagtcaggtg aaatacatgt atcccacctg actctatgct
    10801 ttatctaacc tttattattc tcttttatac aatttctgca ccgaatggca tcaacgccaa
    10861 tcgagcaagt ttgaaagatt gcttggcaaa aggtatccct atgatcgtga tacatagaag
    10921 gatgccgctg acgacatgtg cgagagcaat tggtaggcct gaaacgatca gccagatgat
    10981 attaacaatc aatgacatgc cagactggtg ataaattact tctttgccaa aaggcgcaaa
    11041 agaaagggag gcgatcttaa aacattgcat accgattggg atacctatga tcgtgataca
    11101 ccaaagtatc cccgctgcta accagctaag accaccgatt agtccgccga atataaacca
    11161 gatgacattt cctaaacaac tcattgtatt tctccttcta ttactgtttt tgattaaaac
    11221 tgggcaaaaa atgattttat tcttcttttt ttagcttcca gtatcaaata ttctgcaaat
    11281 tttttttgga tttcttccgt attttctttt gttactaatg tgtgttggat tagttttcct
    11341 gatggtcgct gatccaatcg ttcttctgac tgttgcacgt ccgcttgcgc aaatccgata
    11401 atccgttttt cttttgttac agcaacgagc aatagtttat tcttatcatt taggtcagct
    11461 gccgtttttg cttttacgaa tgattctgga tgatcagtaa tcagctgatt gatttgaggt
    11521 agatcttctt ttactgccca ccgtatttcc atcatttctc acttttcttt cgctcatttt
    11581 tatctccact aaaaaaatcg actgcggcaa ttgcatctat ccagctttgt gcaatgatct
    11641 catgtccgcc aatcgttggg tggaccccat cttctcttgt atatttcgaa aaaccataaa
    11701 caatccctaa agcattgaat ataccatcta aaggaaccag caatgcgcca tattccttag
    11761 caagtttacg aacaatttgg attttagggt ctaagtcttt acgccagcca tgacggtcgt
    11821 cggttatagg aagtacaaac ggctccatca agatgatgtt gcagattccc actgtttgaa
    11881 gttcatttag taattttcga taaacggatt caaattgctg agcagatttc tcagttccga
    11941 atatagcctg atcgctagta ttatgccagg tatcattgat tccgatcaaa atcgatacat
    12001 agtcaggttg taaagctaaa caatcttctt gccagcgtac ttgcagatct gcaattttgt
    12061 ctcctcctat cccacggttc atgcattcaa attccatcgt tggatattgg gagattagtt
    12121 ttccggcaat caaaagtgga taacctttac ctagatcagt tgcttctgct cggtctcttc
    12181 ctgcgtctgt aatgctatca ccgataaata atatacgttt tttcatttgt caaaaactcc
    12241 tttttgaata aaacgatgat tttcttcctt atattatccc ataagcccta tcaagacgaa
    12301 agagaaaata tatgtataaa aaatgacacc agcctagtcc cttcaaacaa ttgaatgaac
    12361 gctcatcaag tgtctagttt tttatgctat ttttttctta acgtgccgga ttccccttga
    12421 ttccttcgtt gtttggtcca gagagatcga tcacacctaa gcttccgtca atcagaccac
    12481 tgatgacgcc atcagaacat atatttatag gctcatctaa gacttctagt aaatgtccct
    12541 ttactaatat ctcttctaga ttgcttggga tagattggtc ataactttat ctggtccgat
    12601 gatttcaagg gtgaattgaa cttacatatg gattattgca tgctgaaaat acggacctac
    12661 tccatcttcg aatgttacta ttagtttgtt ttcaggtgct agatgctgct ttatttcaac
    12721 agcagaagca tcatcaaatc agatttccat ttgaattacc ttctttgtaa atgtttgatt
    12781 gattgcgatt tcgttataga accttgtgaa tcaaatagca atttcttttg ctttcttctc
    12841 ttgtctgctg gaaacttcct ttatcccgta ttttaaaaaa agaactgcga gagttcgcag
    12901 ttctttttta gaataaacgg tgctctccgg ccaactcctc ggtcacaagt cacaatagtc
    12961 atcaaacatg aaaaactgtt ttttgaaatt actccttgtg actcggagct gaacggcagg
    13021 cgcacaacct cttccttaaa cggtgttcaa aagccagttt ctcggtatta agccaaattt
    13081 atgcaaaaat gtggaaagcc atttccacaa aatttttctt aatactcgaa actaaacagc
    13141 tttttcacaa cctctccact aaacggtatt caaaagctta catctgcggt aataagtccc
    13201 gccaattcaa aaacatgaac agctgttttt gcttggctgt tctaattact tgatgcagaa
    13261 cagctttttc atcacctctt atggataaat tcggttcaac aaacgtggga atggaatagc
    13321 ttcacgtaca tggtcgatac cagcaatcca agtgactgtt cgttcaagac ctagaccaaa
    13381 accagagtgc ggaacagaac cgtatttacg tagatcaaga taccatgaat attctttttc
    13441 atccaaaccg tgattacgga tttgttctag caagaaatca tagtctgttg cccgttcgct
    13501 tccgccaata atttcaccgt aaccttctgg tgcgatcata tctgcacaga tcaccacgtc
    13561 ttctcttgtt ggatgtggtt tcatgtagaa tggcttgatg gcttttggat agtttaggat
    13621 aaagacaggc tgttcgaatg aattcgcaat gaacgtttca tgaggtgaac caaagtcttc
    13681 gccccattcg atgtcatcaa atccattttt cttcagtaat tcgatcgcat catcataagt
    13741 aatacgaggg aatggcaatt ttgtataagt ttttaagact tctttgtctc gtcctagtac
    13801 atctaatgca tattcgcaat gatctaaaac attttgtact aagaatgcta catattgttc
    13861 ctgtacttct aaactttctt cttgatgagt gaaagccatt tctggttcga tcatccagaa
    13921 ttcgatcaaa tgacgtcgtg tttttgattt ttcagcacgg aaagtcggac cgaatgaaaa
    13981 gacttttccg aaagccatag cagcagcttc catgtataat tggccacttt gagataaata
    14041 agctttttga tcaaagtaat ttgtttcgaa tagatccgta gtgccttctg gtgcagaacc
    14101 agtcaagatc ggcggatcaa ttttgacaaa atgatgttga ttaaagaatt catacgttgc
    14161 acgaatgatt tcatttctga tctgcataat cgcatgttgt cttgaagaac gcagccataa
    14221 atgacgatga tccatcaaga agtctgttcc gtgttctttt ggtgtgatcg gataatcgtg
    14281 gctctcgctt accacttcca catttgtaat tccgatttca taaccaaatt ttgaacgact
    14341 gtcttcacgg atttctccag ttactaacac ggatgtttct tggtgtagat ttttagctgt
    14401 ttggaaaact tcttccgaca cttcgctttt tacaactaca ccttggaaaa aggctgttcc
    14461 gtctcttaat tgtaaaaatg cgatttttcc gcttgatcgc ttatttgcga cccaagcgcc
    14521 gattgttact gtttctccca catggttttt cgaatcgatg atttgaattt gttccacgta
    14581 tgactctcct tttatattcc ttgaatttct ttaggattaa ttttgacttt tactctcaat
    14641 aaattgcttg attctgcgta ccgcttcttc taacgtagcg cgatcagtag cataactcat
    14701 gcggacattt tctggtgccc caaagccttc gccagtcaca agcgctaccc ctgtttcttc
    14761 taaaagatct tctacccatt gtgtgacatt ttcatattta cacatgcgta gcgtttcttt
    14821 tacattagga aaaagataaa aagctccttg tggcttttca agagaaacac ccggcagttc
    14881 tgccacaagc gaatataacg tattcaggcg ttcttcaaag gcgttccgca tttcttccac
    14941 tgtatcttgc tcgcctttca atgcttcaac agctgcatat tgactgactg ctgtcggatt
    15001 actggttgac tgggaagcaa cagcgatcat tccattgatg atcacaggat ttcccaccgc
    15061 ataaccaatg cgccagcctg tcatcgcata tgttttagac acgccgttga tgatgatagt
    15121 ctgatttttg attgcttctg aaatcgttgc aattggagta aactcattgc cattataaac
    15181 taaacgacca taaatatcat cagcaactat caaaatatca ttttttactg cccattcacc
    15241 gattgcctgc agttcattct tgctataaat cattccagtc ggattcgatg gagaattgat
    15301 gattacggct tttgtttttt ctgaacgtgc ttgttctagc tgttcaacag taactttcca
    15361 gctattggat tcttcccctt tcacaaagac aggaagtcct tctgccagtt ttacttgctc
    15421 accgtaactg acccagtaag gcacaggaat gatgacttca tcttgcgggt caaggatcgt
    15481 ttggaaaagg gtatacaaag caaatttcgc tccgtctgtt acgactgttt gtgaaggttc
    15541 atagacaagt ccatagtttt tcttcagata atcaacgatt gcctgtcgaa gctctgggat
    15601 tcctgctgtt ggtgtataat agctagcttt cccattgcgg attgcttcga ttgctgcttc
    15661 ttggatgttt tctggtgtcg caaaatccgg ttctcccaca gtcaaactca gcacatctct
    15721 gccttttgct tttaatgcct tggcctttgc cgcagctgcc aaagtgacag acggttctaa
    15781 tcgttttgtt ctttttgata actccatccc attcattcct ttacctttta aattcccttg
    15841 attgtcttga cttcatctcc agattcaaag ccaatcaggt aataattcag tttcccattt
    15901 gtttcttttc ctactacttc ccacacaggc tgatcatcat acatccctaa agcagctttt
    15961 tcgatttgga tttcaggatg ggccgcagca attgtctgtt ttgcttcgtt ttcagtcagt
    16021 ccctttgttt gatccaatac ttttactttt tcaccagatt taggaatgat aacggcgatt
    16081 tcttttcctt tatcatttgt acctgtcagt gaaaagtatg tcttctttcg agtaaaccaa
    16141 taaaaatgat cggtttcctc aagatttgca tatttctttg cgatttctac tgcttctttc
    16201 ttcgcctgca ccgccggacg actggaacgc aagtaaaaaa tcgagctgat cacgatgacc
    16261 gctaataaaa atacgatcaa gccaagtaac acgcgattaa tcgttttttc ctttgtctgt
    16321 tttttcttca agggtcgtcg ctcctttatc ttcattcctt ttcattatag cagattttaa
    16381 ttatgaaaaa agacagctcc tctaacttcc ttcttcattt ttctttaaga attcatggat
    16441 atcctgatag atttcctcca tagctagctc tttgatcggt acttttttcg gtaatgcatg
    16501 gatgatccgt gcgccatatt ttgcagtgac tagtcttcga tccaaaataa gcaatacgcc
    16561 acgatctgtc tccgtcctta tcaagcgacc taatgcttgg cgtaacttca aagctgcttt
    16621 aggtacggat tcctggtaaa aaggattgat cccctctgat tctaaataag cgttcctagc
    16681 tttgaccatc gggcgaagcg gattatcgaa gggtaaacgt gtgactacaa cgatctgcaa
    16741 agcatctcca ggcaaatcta caccttccca aaagctgtca gcgccaaaca atacgctttt
    16801 ttctgacaaa atgaagcgtt tcaaaagctt ctcccggctt ccaccaaacc cttgagctag
    16861 tatttctcgt cctttttcta gcatagacag atgcattttc tgatagacct tctgcaaaac
    16921 atcatgagaa gtgaataaca caagtattgg ccgatcttct tgttcgatca gacctgtaag
    16981 tgctgtctct aaataatcga tatatgcttg attgctgact tgatggacgg caggtgcctc
    17041 ttttggcaca tagatccttg cctgtttctc ataatcataa ggagaggcaa tcactttaag
    17101 aggtgctgct tcaatgccaa gcctcttaga gagatagtgt cgattagggc cgatcttcag
    17161 cgttcctcca atataaagaa tacgatcata tcgaggatac caaacagtcg acggcaacat
    17221 agccgcttga aaatcatgga gatgaaaaat catctgctgc gctgtgttcc caggaacgaa
    17281 ccaatggatc aaatgatctc gccagtcttc cagccattga tccatcagca agtattgctt
    17341 gtctaattga tcaaataggc tatataaact tgctaaatcg atccgcatct ggtttgtcca
    17401 gctttcttgg ataatctcaa aagtcagacg catttgtgac tgtagctgct ggatctcctg
    17461 ataaaaaagc tgcaggtgat caatggctgt cccagattcc agtggcagct gatccaacat
    17521 ctcttttgtc atcatgactt cttctggata ctgtccgtta ggttgcttgc cgctcactaa
    17581 actcattaat ccttctgcca tacaaatctg tgcttcgcat agcgcagaaa gttcttctcg
    17641 ataaatcgat aaccagcgta aggcttcatg ttctttcggt aaatagcttt gtattcggtc
    17701 aaacagctga tttggttctt ctaattgctg gatttgttta tggaaatagt taatacttaa
    17761 tcgtttgtca tttacttttt cagcgatttc cggcaaatga tgtacttcat cgatcaacaa
    17821 aaatggacta gctggaagca atggttcttt tcgctgtgtt tcttgtacta aaaacgcatg
    17881 attgacaatc aaaaaattac tttgcctgat tttcttttgc aagaaacgaa caaagtcttg
    17941 ttcgtaaaat gactgatttc ttgctaaaaa tccaatacct ctgtgcgcga tatctgcaaa
    18001 gaatgaatgg ttcaaatttg ttaaatgtaa ttcatccaaa tcaccagtct tcgtttgcgt
    18061 cagccaaact aagaccgcca tttgatacaa agcatattgt ttttgttctg gcggttccac
    18121 aagtgtgcct ttaaaacgct gcaaatcaat atagtggcga tagcttttga taattacagg
    18181 ttgtatgggc tgatctagca attgattcag caatggaatg tctttttcta tgatctgctg
    18241 ctgcaaaact agcgaaacgg tactgatgac agcgggtttt tcaggtgtag ccaaataact
    18301 caatggcagc agataaccga ttgttttacc cattcctgta gctgcttcga tcatcaaatc
    18361 ttttgattca tcttttgtga aatggtcgta gaccgcattc atcagtctgt tctgttcttt
    18421 tcgatacatc agtgttttac caaacatttt ttcttttgct tgtttttttc ttggatatgt
    18481 ccgctcgcca taatggacgg atgtgaatag ttccacttct tttttctgca aagctagccc
    18541 atcgacgatt tctaatgagg gatcaagtgg ctctggtttt tctttcattt cttcaatcac
    18601 atgataaatg aaacgactcg tatccatacc tgtgtgtcta cttaatcgcg caatctgctc
    18661 taacgtgatg attggcaatt ttctcatccg ttcttcgatc agcaaaagaa gttgacctgt
    18721 cacttcggca tcactatctg cctgatgagg attctcatga ataaatccaa ggctttctga
    18781 caaatcagct aagcgaaagc ttggttccgt cggcaagaaa atttgtgcaa gttctactgt
    18841 atcgatgcct ggtatcttca aactaggaag tccgcatcgc atgagttcat ggttcaaaaa
    18901 attataatca aaataaatat tatgcgcgac aaatatggtg tctgccaaaa gattgtaaat
    18961 cgtttgggcg acatcttcga aataaggcgc tttttggacg cgttgattcg tgatccctgt
    19021 taaatgctgg atttgttttg aaatcttccg ccctggatga atatcgatcg aaaaacgtga
    19081 agtgatccga cctgattcaa tcatgacgca gccaaattgg atgatccgat cttcttttgg
    19141 attcgtccca gtcgtttcga tatcaacgac tgcataagtt cttggtttca aaatatcttc
    19201 ctcttctcct gcctctaatg ttcttttgaa attatactac aaagtgcaga aaaatactct
    19261 catcgctttt taaagaaaat agacaaaaac gcccagacac gcaaatgtct gggcgtttat
    19321 tttttagtat aggttaatta agctttagta acgtttgttg cttgaggtcc gcgttggcct
    19381 tcttcaacat cgaaagttac tgcttggcct tcttctaaag ttttgaatcc gtcgccttgg
    19441 atagctgaga aatgaacgaa tacatcgttt ccgttttctg cagtgatgaa tccaaatcct
    19501 ttttctgagt taaaccattt tactgtacct gtttccataa taaaaatcct ccttgtgtat
    19561 caacacatat tttgcaatta cttgaatggt gtatatctgg aagatgttta tttgaaacaa
    19621 gctaccacag attaccgaac aaaaactact cctatagtat atcataccgt ttacaaaaaa
    19681 gctagagttt ttcgactttt tttattaaaa aaagttttct cagcgattac ataaagtgaa
    19741 aaaccgaact tttttttaaa ataaacgaca tattgttcag ttggtgtttt tttgctctga
    19801 tgttcttttt taaactaaaa aaattattct ttctgactac ttatcggttc tgtttcaacg
    19861 gtcgaggctg gggaagattc tttagtaggt ctgatgttct catggtattt ctgatagcct
    19921 atgacagtta ccagaagaac aaggcaaacc aatacgacca acgagattag tttttctttt
    19981 ttgctcatat ctatacctca taaataacag gatgatgtcc atcatatttc tgagtatgag
    20041 taaaagcaaa agctgcagct gtagaatgta agaaatgcca gcaactttca taatcacagg
    20101 tcggacagta ccaaaagtaa ccaaatcttg gctgcaaaga ccgttcttct gtttcaggaa
    20161 tcgcagaatc aagatctggt gtctgtacat aaacattttt gtacagacgt gtgcctgtaa
    20221 taggaaaccg ctgtgtttct tcagcaaaaa ctggctgact tgttaaactt agggatagag
    20281 acagcaaaca ccataacagt ctttttttca taaagacctc cttatcgata agtttttccc
    20341 aattaaaatc atatctcaag aacgcccgtt attcacattt tgttcataaa tgatgttttt
    20401 tgtatcataa tcgtcaaaaa gaggtcgtga ccacgtcaca acctcttttt taaacggtgt
    20461 tccagaagta gcttcttcgg aaataagccg aaatttcaca aaaatttgag aaataatttt
    20521 tgtcaatctc ttcttatttc ttgaagctga ccacttctgt cacaacctct tccttaaacg
    20581 gtgttcaaaa gcttgcatct gcggtaataa gcccaccaaa caaaaaatat gaagagctat
    20641 ttttgcttgc tgttcttatt acttgatgca gaacagcttt ttcacaacct ctcatacacg
    20701 gtgtttaatc agctgacctt cggtattagc tcaaaaaacg gcaaaatatg tgaaactatt
    20761 tttccgtttg tttctctaat actcaggtca aaacactgat ttcacaacct cttttaataa
    20821 cgaagaatcg ctgtcagact cttttcatct ggcgcatctt tttgatccaa aataaacact
    20881 tttccgccat taatgatcac atcatctgct aatgcattca acacttgacg ccgatcatat
    20941 tctgtttcag gatcttcacc gaaaccatca gctaagtttg acgtagcgat aaataaatgt
    21001 gacacttttc cttctttcgc agctggaacg atatcaacta actgatcgat gaatttctta
    21061 tctaagagtt tattgtattc ttttgattct tgagctgcga gttcacttga cagcttcttc
    21121 gccccttctt cgatatctct aaaggatagc tgcgcaggag aagcagaaat cgcaacgtct
    21181 gcacaataat agggattttt agcaattttt ttgaacatcg tctgattttc tggtagagca
    21241 aataaataaa tcggccattg ttctggattt tcgaaagaat ccttcaagta cgtatcaact
    21301 gcttggtaat agttgaccca atcgatctct acttcttcat cttttggatt tacgccatgg
    21361 aaagttactc catctcgggc tccgcctcct ccattagaag agaagttcaa accgccacct
    21421 gtcagttcag atcccaatgc agtaacgaca tcaaccggtg ccccttctgg tagagatact
    21481 tcttttactt gtttgttgct gacttcatac aatttcatgg agtcgcggtt caatcccaat
    21541 aaataataag aatagttgaa ctgcccattt ttgataatag ccagtaaata aggaagatca
    21601 cttacatagt attgatcgtc taccgggata ctcaaacgat ggatataggt ttggtcagca
    21661 gttataatga ccgctacact cgtagttgca ctacgccaaa acgaaggatc tcctaacaaa
    21721 ttttcaattt tttcttggaa cggggaccag tcatgttcgg aatatttttt ctcaaaacgt
    21781 ttctttgctt ctttcgcaaa atttttgaat ttgatctgat ctttttccac atcttgatgg
    21841 gcgacatgcg tattcagcat gatcgtgacg aatggtcctt tagcgccttc tgaagtcaat
    21901 tgtgacaata attctttatc cttttttgcc ataaacgtac ccctcctaaa aaaatcattc
    21961 ctttgtttct atctaaagtc taccacaaca ctatttttcc atacaataaa acgtatctaa
    22021 aaaaataaaa cggtttctac ggttttaaat ttagctattt ttttaagtta tcttcataat
    22081 ttcctcaatt atttagcccc agtcttcaac tattcttcat gaaatgctga taaactaaga
    22141 aaaagaataa aagaggtgga tcttatgcat ttgattatga ttttcagttt attaagtatt
    22201 atcagtttat ttgctttcag cgcttcccgc ttattagatg cggaaacaca gcctattcct
    22261 gtaaaagtac gtaaaaacga ccgctaacct tccataacgt gcgttcttat cctaaagttt
    22321 tttcagaaac attgaaactc tctcccctct ctgataaaat tttaatttgt agcgaaacaa
    22381 attaattaca aggagatcgg atatgtccat aaaaaaaaca cgtctagtcc tattattggc
    22441 tagtctcatt ctttgccttg cttcttttct accagctgtt gctgtgcaag ctgaagatac
    22501 tttcaaagta aatgcaaaag cagcctttgc tgtagatgcg caaagcggta agattcttta
    22561 tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc acaaaaatta tcggtcttta
    22621 catcgtcctt gatcaagtaa aagaagggaa actatcatgg gatgataaag tttcaatttc
    22681 agattatgca gaaaatttga gtgtcacccc agatttatca aatgttcctt tgcataaaga
    22741 aaacacctac accgttaaag aattattcga ctctgcaatc atccagtcag ccaacgcttc
    22801 aatggttgcc ttggcagaaa aaatctctgg cagcgaagca aaattcactg aacgaatgaa
    22861 agaacaattg aaagattggg gtatcaaaga tgcaacgatc gttaatgcat caggactgaa
    22921 taactcttat cttggcgaaa accgaccaga aggtactgga gaaaacgacg aaaatcaaat
    22981 gtctgctcaa gatgtggcta tcgttgcccg tcatttgatc ttggattttc cagaaatact
    23041 ggatgtatct agcactacga cacaaatgtt tggcgaaaac acgcaatcac cagtagaaat
    23101 ggtcaactgg aactggatgc tcccaggatt cgtgaattat aaagaaggcg tggacggatt
    23161 aaaaactggt acgactgaac ttgcaggagc ctgtttcgtc ggtacgatca ctaaaaacga
    23221 tcaacgaatc atcactgtcg tattgaatgc agacggccat gcggaaaacc caagtgcccg
    23281 tttcaatgaa acagctcgct taatggatta ttgctacgac aattggtcag aaaaagagct
    23341 tggaaaagcc aatgcaagta tccctagtct aaaaaccatt gatgtaaaag acggaaaaga
    23401 atcaacagtg cccgttgtgc ttaaaagtcc tgtaaaagta tgggtacgga acgatatgga
    23461 tactggaaaa ttaacaatca caccaactct tgacaaaaaa caagtcactg acaatgagat
    23521 ccaagcacct atggataaag gaacaaaaat cggtaccgca acgatcacct tggcagaaga
    23581 taaattaggt tatctagaag acaacaacgc gccatccaca gaaatcatca cggataaaac
    23641 cgtagaaaaa gcaaatattt tcgttattgg ctggcgacgc gtcgcagaat ttttcggtaa
    23701 cttgttttaa ttgaacaaaa agaaaaaagc atctttccat gtggaagatg tttttttgct
    23761 ttttctagtt taaataacag cttttttcat ctattttcgt tatactgtat aagaaaaagg
    23821 agttgaattt atgaatctaa ccagagatct gatttttttg gttctctatc ttattggggt
    23881 attctccatc gtttattggc gaaaacagaa aaaggatcct tccttgttct tttacagcag
    23941 tacgtggaca tttgcggtaa tcttgactta ttttgtcgtg ttggaaattt tttattcgac
    24001 cttttatttt ttgattccct tagtgttttt cagtatcttt gccttttcct atttttcaga
    24061 aaagcgaagg ctgctgaatg gtcttttatt caatgttttc ctcattagtt ttggtatcta
    24121 cttgtttgtc ttgctatacg aaacacaaaa tatttttctt ggcggactga ttgccttgat
    24181 cacgatcccg ttactgcttg tctttctatt cggcatttat ggattgatcg tttttctttt
    24241 ttggaacggt gtcacagttt tacgtagaga gtcgcattca ttagctaatc ttttaacgtt
    24301 gatactagcc atttttctta cattgtttct tgtttttgac tttttcttgt taaaatattt
    24361 accacaatgg ataaatgctt tgtttttctg catcccattg atcttgatct atctatttat
    24421 cgtattctac aactttttga ctgtctcatt cttgtatcag ttcaaccgcc ctcgatacaa
    24481 ccaagacttc atcgttgtgt taggcgccgg gttgatcaat ggagaaacag tttctcctct
    24541 tcttgccaag cgaatcaata aggcgattgc tttttattgg gcacaaagcc gtgcgacatt
    24601 aaatccgcct atcctattaa tgtcgggtgg acagggagca gacgaaaaag taccagaagc
    24661 aatggcgatg aaacaatatg ccatggaaca aggaattcct gaaagagata ttcttgtcga
    24721 aaccaattcg acaaccactt tggagaatat gcgctattca aaggaaatca tggatcagca
    24781 aatgaaaggg ccctatcgcg cgatcttcag ttccaacaat taccacattt tcagagctgg
    24841 tctctatgca cgacaagcga aactgaaggc aaatggcatt ggggcaaaaa cagctttcta
    24901 ttacttgcct aacgcgtttt taagagaata catcgccatc ttgatgatga acaaaaaaag
    24961 acatatgatc atttgcggat tgcttttcgc aggttccgca ttcttatcac tgatcacttt
    25021 acttttctaa aaaaccaagg tgtgacaaaa catatgtcac accttgtttt tttcttttat
    25081 tctcttgacg attggcaaga atagtattcc ttttttgacg gctacttgct gtgcagaata
    25141 aataccgctg tttcctgaac acataaagct gatcaagcag atcataaaga agtaaacagc
    25201 agcttgtgaa ccaaataatt cgattcccat cacaaaacag gcaatcggtg tatttgtcgc
    25261 accagaaaat accccgataa aacctaatcc agcaagaaaa ggaacagaaa catggagcaa
    25321 aggcgctagt actgcgccaa gcgttgcacc aatctcaaat agtggtgtca cttctccccc
    25381 ttggtacccc gcacctaaag acaagaccgt gaagaataat ttcccaataa aatcataagc
    25441 atgtgcctgt ccattaaatg attcctgcag tatcggaaga ctcaacccaa ggtaacgttg
    25501 tgtttgcaaa atcaacgctg cggctacaac tactgctcca cctatcgtat ttcgccaaac
    25561 aggatgagga atccattgcg cataccgcgc ttttaaaaag acgatcgaac ggctgaatac
    25621 ccaaccaatc aaaccaaaag caatcccagc aacaaaaact ttgaagaaca gcaacatact
    25681 ccattcagga atcacaccca tttggtaatg tagatgagaa acaccatagc tttctgtcat
    25741 gaaatttgca aaaagcgcag caaagaagct aggaaagatt gcttctgttc ggactttacc
    25801 gattgccaac acttctaatc caaataatgt tccagctaaa ggtgtgccaa atacagaact
    25861 aaaacccgca ctgattccac tgataaccaa aatctcccgt tctgctttat ccaatcggaa
    25921 taaatgcgct atattatcag ctaatgctcc ccccatttga actgctgttc cttcacgacc
    25981 aacagatccc ccaaataaat gggtagtgat ggtcccaaac aaggtcaatg gaatgagccg
    26041 caaagggatc ttctcttctc ctccattccc ttgatcgatc actaagttat tcccacgact
    26101 agaaagaccg ccatgatacg cataaagata agcaaaaagc gcgccgctga ctggcaatag
    26161 ataaaatagc caaggatgtg ctagtcggat atctgtcacg aacgtcaggc tatttaagaa
    26221 aaaagcagac aagctcccca tgaatactcc gagaatcgct gtgaccacca gccacttcaa
    26281 catgtacatc aaaatacgca ctggactcgg taattgtttt tccataaaaa attcctcctc
    26341 aaataaaaaa acgcctacta aagaaagggg ctggccccag actttagtag gcgtcattag
    26401 ctatcttacg ttagcattta aaggcgaaca ccatcaccta ttcacttcca ttaaaagata
    26461 gcatattttt ctgtaaaaaa caataaaatt atcgttcttt ctttacacgt tcagcaaatt
    26521 catagaaagg agccaatttc gttaactgtt gattacattg atcactatca tgacaaatat
    26581 aattcccctt tttcgtatac gtgccatcag aaccggcttt cgttgtagaa agaaagagcg
    26641 agacattcga tgttttctga cagatcgcac agattccctt attaatcgtt ggtgataaag
    26701 taccgctgat cccttttaat tttccatctt cgtaataaac catgaatttt ttttgcgtcc
    26761 ctggatcatt ccaaccgatg tacgtatgtg cttgcaagtc gatttcattc caagcgggtt
    26821 gtttgagttt tttcactttt cggaataatt tctcgatttg tggtttgctc ggctgcataa
    26881 acggctggac gatttgcttc agctcctcca atgctcgttc tgcttgcgtt tttgtcagtt
    26941 ttacatctaa aactgtcgtt aaaaacgtat cgatttctga tggttcgtaa cctaatacat
    27001 cgcgaatctt ttcagctgct agagcctgaa ccgtttgtac cgtttttgag tcattgacag
    27061 atgagtacgc atttaataac tgctctactt ctctttttat aaaaaaatat tgatatggtt
    27121 tcattgtttg ttccatgatt ttaaagtcct ttcttctaac caaagtgcat actttgtaga
    27181 aaaaagtgat cttctgcaaa gtatgtgtta cctgaagatc ccggactctt ttaaataaga
    27241 tacgttttgc atcttatcat cacccccttt aatgttcatt cttctatgta catgattcat
    27301 tcgataaata aaagtaaacc gtatcttgag cagatagtca actgcaaaca gaaaaaggac
    27361 tgtgacaaaa gtcgtgtcaa agtccctttc tacaaacaaa cggtgttcca gaagtagctt
    27421 cttcaaaaaa taagccggaa tttcacaaaa atttgagaag caattttcgt aaattccttc
    27481 ttatttcttg aagctgaccc acttctgtca caacctcaat atggtctatt attggtttta
    27541 cctgttaaat cgaggattct tttccgaagt aacgttgcca tctcttacgc atacttgctg
    27601 acataggctg agcggcttct ttgactgcgc agtatttgtc tacgaatgtt acgatatatc
    27661 cttctttgta cttaggcggt gcaatcgttg cgccccacat gtgcttcaaa atgatatctc
    27721 gctcaagatc cgacaaatcg gtgatctttt ctgcattctt tacagcgatt cttggatgga
    27781 tatacgcatg tgtgccttca tcaaatttcg tcgtacgcca atcatagtag aacagatcat
    27841 gcaaaagtcc agcacgcgct gttgctttag cattgccacc ccattttttt gcgagcagat
    27901 aactatagta agaaacactg atggaatgct ccaaacgagt ggaatgaaca tgctgtgtgt
    27961 aattcgctaa ttttttcact gcttctgttt ctaaaagatc ttctacataa gacatatatt
    28021 cttcgtcttc acgccatttt tctgtcataa ttatcgatct gccacctttt tgaatttcat
    28081 tttcttctga aattgatcta agtataccac cagtgttcgg attattctag tcgccttgga
    28141 taaaatagcc aaagcttaat agttccttaa tcataaagaa aaatgataaa gaacaatccc
    28201 tgccgcaacc ccaacattca acgattccgc atttcctttc atcgggatat atacgttctg
    28261 atcagtcaaa gacaagattt cctgacttac cccctgacct tcgttcccca tgattattgc
    28321 gaagttatct gatttttcta ctttgtctaa tgcgtgtgct tcttcattta attctgtgcc
    28381 atacactgta aaccctttgt ctttcattaa aggaatcact tctgtcaaat ctttttgcaa
    28441 cacaggcaaa tgataattgc ttccctgcat gctgcgcagc acctttgtac tataaatatc
    28501 tgccgttcct ttgcctaata aaacaccagc catatcaaat gcatctgccg tacggatcat
    28561 cgtccctaca tttccaggat cttgtacatt atctaataac agccatcctc ctgaaaaatc
    28621 tggcgtgcct tcagccgtta acgccatcac tgctaagatt ccttgtggtg taggtagatc
    28681 cgatacagca tccatgacct catccgaaac tagaaaagta gaaatctctt tgtttgcggc
    28741 cagccagtct ccccattctt tcatgcctcg ctgtgtcaca aaaagttctt ttatttctgc
    28801 atcagacgac gcagcttctt cgatcagatg gaacccttcc aaaagatatt cttccttttc
    28861 ttcccgatat ttctttttat gtagtttttt taattctttg attcttggat tttttgctga
    28921 ttggatctct ttcacattcc tcacctcccc atgattatat catggaatag gtgcttgagc
    28981 ttgtttcatc ctaaaaaaat cggtatcatt aatttataaa ataggaaaga aaggtgacga
    29041 acatgcgcaa agttaaaatg aacgtccaag gacgcgtcca aggcgtagga tttcgctaca
    29101 tgaccaagat ggtcgctgat caactaggcg tgactggaac ggtaaaaaac gaagacgacg
    29161 gctcagtcac aatcgaagca atcggcaatg acgacatcat ccagaaattt attgaagaag
    29221 tcaagaaatc accgagccca agtggacgag tgcagtatgt ggatgtccaa gaagacccga
    29281 tgattgagga acgaaagaaa tttgatgtgg tgggataagg ttgtgaaaaa gctggtctgc
    29341 atcaagcatt aaggacaggt tgtgaaaaat agctctccat atttttcaac aggctggact
    29401 taatgccgta gatgcaagct tttgaacacc gtcaataagg ttgtgagaaa gtcgcttagt
    29461 tttgagtagt aaggagaatt ttgtgaaaat ggctttctac attttttcat aaaatttgac
    29521 ttaataccga gaaactgact tttgaacacc gtcgataagg ttgtttttga ggcgctttgc
    29581 ctcgagtatt aaggagaaac attttcaaaa tagcttctca tattttgtta ataccgagaa
    29641 actgactttt gaacaccgtc gataaggtta ttcttgaggc gctttgcctc aaaaattaag
    29701 gacagcagtg aaaaagctga tctatcactt gcagtgagtt catttgactc cgctttttcg
    29761 ggcagaaaaa aagtttttag tttattaaag taagaaagaa acacttggaa tcattctact
    29821 ttttcctagt atttctttct tgattttttg tctttttttc aaaatttttc gctacgtaaa
    29881 agaacgaata tttatatgaa atttctatga agttgattga attccatgcg cttttttagt
    29941 atagttaagt ttgtgtaaaa attatagaag aggaagtatt ctatgaataa atggaaaaac
    30001 tggttattgg gatccggact tgtcagtatc ctgctctttt tatctggctg tgtgcggatg
    30061 gattcaaacg gaaaccctga cacttcggga atcgtttatc gagtactcgt ccatcctatg
    30121 ggccaagcga ttacatatct agttgaaaat ttcaattggt cttatggctg ggcagttatt
    30181 gcaatgactg tgatcgtccg tatcatcatc ttgccactag gtattagtca atcgaaaaaa
    30241 acaatgatcc aatctgaaaa aatgcaagcg ttaaaaccac aagttgaagc agcccaacaa
    30301 aaattgaaag ctgcaacaac acgtgaagaa caaatggcag cacaagcaga aatgcagcaa
    30361 gtataccgcg aaaacggatt gagtatgacc ggcggaatcg gctgtctgcc tctattgatc
    30421 caaatgccga tcttctctgc cttgtacttt acggcacgtt atacagaagg tattcgggaa
    30481 tcatctttct acggcatcga tttaggctca ccaagtatgg tacttgttgt cattgcaggg
    30541 gtcgcttatc tgcttcaagg atacatctca acgatcggta ttcctgaaga acagaaaaag
    30601 acgatgcgta cgatgctgat cgtctctcct gctatgatcg tcttcatgtc gatcagtgcg
    30661 ccagccggtg ttacacttta ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc
    30721 atcacaaacg ttatgatgaa accacgtttg aaagcacaag tggcagaaga gttgaaacaa
    30781 aacccaccaa aacaagtcgt cactccaaga aaagatgtga cagaatcagc taaaccagct
    30841 gacagcaaac aagcaaccaa acaaatcaaa caaccaaaaa acagtacaaa caacaaaggc
    30901 cgcaacgcag gaaagcagca gaagcggaaa taaaaatata tgacaaaaaa ctgtagacaa
    30961 ataaaaaaat ttctttgttc tacagttttt ttgttacaat caaagaaaac gttcgctttt
    31021 cgaggaggga tgtataatga tgttcaaaca atcaatggat agtcgaatgg aagaagacaa
    31081 aatttcgcta gatgcacttg ttcctaaaaa tcatttagtc cgtaaaattg acaagttatt
    31141 gtcatttgat tttatttatc tcattgttga atcaacttat tcgaccatcg gtcgacctag
    31201 cgttgatcct gtcgtcttag taaaattagt attcattcaa tatttatttg ggattcgttc
    31261 gatgcgtcag accattaaat aagtttaaac aaacctagct tatcgttggt ttcttgggct
    31321 tagtttaatt gataaagttc ctcatttttc aacttttggt aaaaactatg cacggcgttt
    31381 cagagaaacc gatttgtttg aacagatatt tatcattatt ctggaacaag cagttgttgc
    31441 tagatttatt catgaagaaa ttttgtatat ggattcaact catattaaag agaatgcgaa
    31501 aaaacgtatt tttacaaaag atatggcaca taaagaagcc attttatacc aaaaacgatt
    31561 ggaagaagaa atcaatgagg caagaattgc cgaaggcaaa cgccattttg gttcaatcat
    31621 tcgtcaggag gtggtcgaaa ggaaatttag cgtcgcagat ccagaaattg gttattatgt
    31681 aaaaacagaa cgagaaaaac agtttgctta ttcttctcat actgtttgtg atgaaaatgg
    31741 ttttgtatta gatgtcatga ttacgcctag aaatctacat tacagccgaa tgctcgtgcc
    31801 acaaatcgaa cgtgttaaat cacgttatgg tgtagctgct gatgctgcgt acaaaacacc
    31861 ttggaacgcc aagtatttaa tcgaccgaaa actacgaccc acttttcctt atactcgacc
    31921 caaaggaaac aaagaacgtt ttaaaaagaa agattttgat tatgatccct attataactg
    31981 gtacctatgc ccgaatgatc aaacacttca gtttcgcaca actactcgag atggctataa
    32041 aaaatatgta tctaaatctt ttatttgtga aagttgtcca ttattgaaaa attatacaga
    32101 aagccagaaa caccaaaaag aaatacatcg acatatttgt gaagattact tagatgaagc
    32161 agaacattta cgccatacgg tgtacaatcg cgaaaaatat aaaaaaagaa acgattgaac
    32221 gcatttttgc agacgcaaag gaaaagcatg gagtgcgcta caccaagtat cgaggcttgg
    32281 aaaaaatcag gtgcatacga tgcttgtttt tgtcgcaatg aatctgaaaa aattagccac
    32341 ttggcagtgg gagcatatgt ctttatatct tttattatac aaaaatagac aaaagtatca
    32401 gtctacactc ttagtcaaga ggaaactgat gcttttatct acagtctgag agagtgggac
    32461 aatagtcctt tctccaaaag aaaacaagtc cgactttgat agttaatttt aaaatcggac
    32521 ttgttttttc ttctttacgt cttttcctct ccatgtattt ccctaatttt cttaaattta
    32581 acgccatgag tgccaagcca atgttaatct tggctccttg tttccctcgt aagtggaaat
    32641 ccgtttccga tagatcgaac cttctttttc ctctaaaaac tttttttaca ttctgctttg
    32701 aaataacgcc atgtattatt cactaaaatt tgtcggtttc gctcactttt tgctttcgta
    32761 cattgactac gaacagggca gcaccaccat aagccgcctg ccagttacct ctcactctta
    32821 ccgggtcttt cagaacaccc ggatgctcta acacatcact cggctaggct ccgttattga
    32881 agaagaaagc cccatatctt tccatggcat cctcggccag cttaagaagc tcctccatct
    32941 gttcggagac cttcctcaca tatatgggca aaggccatga agacctccac cagactgttc
    33001 atgaccttct tcagtgctgc gatcatctgc tctctcttct ccatggctta cacctactcg
    33061 acagaatcag cggcatcaga ggcaagagca tccttcatgt gctgtgccag gaagtcatcc
    33121 agctggttca tagaaaaatc gacacccttg ttcatggcct cgctgatttc catcagcttc
    33181 tggttcacct cttcctcaga caggccggtg cgctcacaga tggaatggag cagatgatcg
    33241 tgcatctctg ccatcttctg gtccatgtcg aatttttcgt ggcagcaatc tctgcgccat
    33301 gccttcggaa atacggcttc cccccctcat cagactgtgt gtttggttcc agctctttct
    33361 tccgggattc ttcgctctcg gaaatcggtc tgtacagtga acacacataa atattcttcc
    33421 tatgactggt atcactcatg gcttgtctcc tttatttgtt ttgtcgagtc ctacctcaaa
    33481 ggaggtctgg ccagcatata ggtgttcatc tgactgtccc tttcaaaatt agtgtcctca
    33541 tctatgattt cgggcgtttt ataactcctc cggacaaaat ttttgaaaaa atttgtcgag
    33601 ggcttaatac acctctttca taactgcaaa cgcacgcttc aaggtcttgg tgatttctgc
    33661 atgcgacatg cgcagatccc tcgcaatctg ctgctggttc ttgttcagga agtaataatg
    33721 ctcgatgacc tttctctgat taaaggttag cttctggatc tcttcttgca gacgcttacg
    33781 ctccatcttc ttaaaatcag tcggagcaat cttctccaca atgtcaggag tataggacat
    33841 catgcagtcc tgtgtgtagc tgtcctcgat ggtctgctct atgcctccga ggtatcttgc
    33901 atagttggat tccagacggt tctctgcatc atggtcatgt agatggtcca ctgatagtcc
    33961 atatactcct caaccaggat gaagctattc ttatcggcga accgatacaa cattccattc
    34021 atgcggtcag ctgtgaagat ggagtacata tcattgcgaa tatagaggat aaagtcgttg
    34081 cgatacacgg tcaacagaga atcgtccatc tagaactgag ccacactcac ttggcaccat
    34141 attatcactc agctaacgga agccgggctg ctttacgcct ttggtgctgt ccttgatttc
    34201 cttccatata ctgcttgccg agattgatga ttcttctgac atcgatcaaa gtaacaggta
    34261 atttagaatc ttccacaaac ctgattatct cctctactac tttcggctca atatcttcta
    34321 atgcgatcac gattttatat acctgctact tcacaataac atcctgaaca tcagatattc
    34381 gtccaaaata ctttaatttc gccaatccat ccccataatt agcaaatcct ggttcttcaa
    34441 gtagaatatc ctctttcttt cgatctttca catatccaat aatatttgca tctgcgtctg
    34501 gatctgataa catggccaaa ccatattctt tagccaggtt tccattttcc acaaccaaaa
    34561 ctcgagtatg ggacttgctg cctatctttt tcagtaaaaa ctgaaataca gcattcttga
    34621 cgagcaacaa aacgcacgat atgatccaaa ataaaagcaa tggccatttg gaaaagtatt
    34681 tcacattagc gatatataag tataagaaag caaggaagaa caaacttcca ataccggtta
    34741 acgatactat tttaaaaatc cgttttgata ctttctgaaa taggtcttat tcgttgcacg
    34801 aaaaatcctc aaaaaatctg caatcaaaat actatatagc gcagccatca tcaaatacgg
    34861 aactgacaac atattgatcc cgggagcagc ttctaaaacg tggtaacaaa taaacatggc
    34921 caatagatag gctacaaaaa tagatgctgc atctccaata cagtcaaaaa ctgtgttcca
    34981 aaatcgttcc ttgataattt cattgattct ccccttataa taatatcgaa tgctccaaca
    35041 tcggtcagaa tcatctcttc tgtctatcat tcgccacgta gaagttgttg gaaaagagtg
    35101 acaaccgttc aagacgaacg gctatattgt attaattatt ctgtgtatca actaaccact
    35161 caacaaattc acgcactgca ccattaccac catcatgttc agcgataaaa tctgaaattt
    35221 ctagaacctt tttaactgca tcgtgcggac aggccacaat accacctgca cttttaacag
    35281 gatgcataca agataaatcg tttatatcgt ctccaatata tgcaacagta cttagatcac
    35341 tagtaatctc aagcagtttc tctattttat tgtctattcc ctgataaaga atgttgatac
    35401 caagttcctt acatctattt tctaatattt tggaacgacg accagtgata ataataggct
    35461 caatattatg ggctcttaca atatcgtgaa tagcgcaacc atctttaata ttgaacgcct
    35521 tcataatttc cccacactca cccatatata tctttccgtc tgttagagta ccatcaacat
    35581 ccataaccag aaatttaatt tggctcatac actttccccc cctttcaata attgatagaa
    35641 atcttaaata cagctttctt tactttagct gattcattca ctcttatgca aggcatatga
    35701 gcatcctcag gagttagtag cagcagcttc cctccttcta agagtacaca attgccaact
    35761 attgaattac tgtaaaacac aatatccttg tcagctgaat aatctacttc aatctgtaaa
    35821 ttagatatag attctactac aatatactcg catcctaaga gaatacattg aatgtctaaa
    35881 tatttcaagt gagattcgta cattctttct tcaaatctat atatatcata ggactcaaca
    35941 ttcagataaa ttccattgga aagatcatat cgaccttctt ctaattccaa caaggaattt
    36001 tttataagaa aatatagact tctggaaatt caatttccat ttttttagac ttaacttttt
    36061 catttatctc ctttatgcaa caataccagc ttttacaatt tgctgccatg taatggtacc
    36121 aacaagcata ccttcatcat cgattatagg aagaatgtta atactattag cctttaaaaa
    36181 tctcaatgca tcgacagcta atttatcttt agtaaatact ttgggattag caatcatcac
    36241 atcatcaatt tctacagaat agatatctac ttttctctca ataattcgtc ttaaatctcc
    36301 atcagtaata atgcctttga gagttccatc ctgatcaatg actgaaacta tacccaaccc
    36361 tttattcgac ataacagaaa tagcatccat taacaatgtt cccgaattga ccattggaat
    36421 ctcattgccg tgggacatta gatcagacac tttaagtatt aattttttgc ccaatgaacc
    36481 tgcgggatga aactttccaa aatcagaatc tttaaatcca taaataccgc tagcaacaac
    36541 agctaatgca tcgccgtaac acaacacact tgtagcacta gaagttggag ccaatcccaa
    36601 atagcaagct tcctcaaact ccggtaatat ctggacaata tcagatgcgg tagcaagcgt
    36661 agattttgaa ttgcctgtta ttccaattaa agtagcccca atcattttaa tattaggaag
    36721 aattttaaca atttcatcgg attcgccgct atagctgata gcaattacaa tatccttttc
    36781 tgaaaccata cctaaatctc catgcatcgc ttcagcagga tgaagtctga atgctggtgt
    36841 tcctaagctt gcaaatgtcg ctgccagctt agcagcgata tgacctggct ttcccatacc
    36901 agtgataatg acttttcctt cgcaattaac aattgcatca agaatacgaa cgaaagtctt
    36961 cccaagacaa tctctcgttc tttttaaggc ctcaatttca atatcaaaaa ctcttttggc
    37021 ctctattatc ttatccattt tatttacctc ttcagttttt aatagcagct ggaggtcttt
    37081 cacatgttgt aacacagtac aaaatgtgaa agacttacca tacatttcta tgcaatgcaa
    37141 gaaaaattat ctaacggcat tgtatacttt tagtacacgc tctaataacc cctcaaattc
    37201 atccaagaga accatattcg gaccatcaga caaggcattg tcaggatcag gatgtacttc
    37261 aaagaacaaa gcatctgcgc ctgttgcaac agccgccttc gcaagaggct caacgttatt
    37321 tctattacct cctgtaacat ctccttttcc accaggcttc tgaacactat gcgtagcatc
    37381 cataacaaca gggtaaccaa acttcttcat ctcaacaata gatgtcatgt caacaaccaa
    37441 tgtattatat ccaaaagaag tgccacgttc gcaaagcata atgttactat tacctgcctc
    37501 cacaagttta ttaataacat ttttcatatc ccacggtgcg agaaactgtg ctttttttac
    37561 gttaattatt ttgcctgttt ttgctgctgc cactagtaaa tcagtctgtc tacacaggaa
    37621 tgcaggaatc tgaagtatat cgcatacctc tgcagccttt tctgcttgcc aaggttcatg
    37681 gatatctgta caaattttca atccataagt ttccttaact ttcttaagga ttttcaaacc
    37741 ctcttcaata ccaggacctc tgtaagaggt aatactagtt ctgttagctt tgtcgaaaga
    37801 agccttaaaa taataatcaa tatcgagctt ctccgtaatc tccttaatag tcttagctat
    37861 taacattaca ttttcttcgg actcaataac gcatggtcct gcaattaaca taagtctatt
    37921 catcttatag accttccttt cttaattcat cttctacctg ctgtatctgc tccggcgtat
    37981 ccacccccac ggtttgatat ttagtttcct ttactcgaat cttaaatcca ctctccaaaa
    38041 ctcgaagttg ttcgagagat tcagatactt caagaggcgt tttgggcatt gtactgtatt
    38101 tcttcaaaaa ccatgtttta tacccataaa caccaatatg tttaaaatgc agagaatttt
    38161 ttccatctct ttcgtatgga acacaaaaac gtgaaaaata tatcgcataa tcattgacgt
    38221 cattgattac tttaacaaca tttggattgt caagttcctc ctgaacttca atatgttttt
    38281 tcaaggttcc catataaact tcatcgttat caaagcaaga atacaaatct gctatcatct
    38341 ctgccttgat aaggggctcg tctccttgga tattaagaac taagtcttca tcccggagtt
    38401 gaaggatctc tgcgcactca gcaagacgat ctgtgccgca agtatgttta tcagaagtca
    38461 tcaaagccat tccaccaaag ctttcaacac agtcaaaaat tctcttatcg tctgttgcaa
    38521 catatactgc atctagcata gctgccttag aaacattttc ataaacccac tgaatcatgg
    38581 gtttactaga aatcatagca agcggcttcc ctggaaacct acttgatcca tatcgagatg
    38641 gaataatagc tattgtcttc atcggttctt tctcctttta agataatcca ttaacaactt
    38701 atctttcata catattagta aaatactata tagtaaaata cacaaaatta ctgtaatgaa
    38761 cgttgatatt actgaatttg ggagcttact actgacatat cctccgacgc ctcccataat
    38821 cagtgcacct atcaaatagt tttttacatt cgtaataatt gatgccattt ttaattctat
    38881 acagtttctt acttcataaa actgaattgc agtaactgta agttcagcaa atattgtacc
    38941 tattgcagcg cctatagctt ccaaatgtgg tattaaagcc aaattgacaa cgagattaat
    39001 cacagcgccc gtcataatag agaaggtata caccctttgt cttttcatgg gaatcaaaac
    39061 agcttgacca accacactag caaatccaat tatcaaaatc aatggtgata gtaactgaaa
    39121 taaggaaact gacttagcgt atccgtctcc aagaaaccac ggtataaaag tatttgcgat
    39181 tataatcgca ccaactacca ttggggcgcc tatgcaaaac acaaatgata ctgcattcaa
    39241 tacttctttt ctaattctat caatattgtt ttctttaacc gctactgcga tatgtggcaa
    39301 cataactgca ccaagagatg taatgactgt catcaacagc ttcactattt tttcaggctg
    39361 cgagtatagc ccaacttgga catccgtaga aaatattcct aatataatct tattaacata
    39421 cgtatagata tatactgccg ctgttggaag aaataatcct aatattggtc gaatatgggg
    39481 tgttatcgat atatcatgaa tacttattct tctaacatat tttggaatat gacaacataa
    39541 taatgcattc cccaacagct cagttccagc caatataact gagtacaata ctacatcatt
    39601 ttcatttttc accaataaga atatcaaaac aagaccaatt aacttaacca ccatacttct
    39661 gattgcagtt tttttgaaat cttccatccc ttggaaaaac caactgacat caaaaagatt
    39721 tgcaactaaa taaacagaca tacttattag taaaacagtg tatgaatgaa gagtagccga
    39781 aataagaata tatacaggaa aaacgataaa cgaagaaata atacggataa caaagatgct
    39841 ccaaaacact ccacttcttc tgatcttatc attctgaaca taagcaatct cacgttgtcc
    39901 atacatgttc gtacctaatt gagcaattat taccgctacc gatacaatgg cgtacgaata
    39961 attaaactcc ccaactccct ccgctttcaa tactctagat acgtatggag tcgtaataat
    40021 aggcagtatc ataaccaaaa tttggtaaca aagattatag gcataatttt tgatcaacct
    40081 attcatatta ctcctccttt atcttaaata taatttcatc ctgccttttc gtaaattctc
    40141 gtactaaaag gcaagcaacc acaacagaaa atatatttgt tatagaaaac gcgaaacaca
    40201 tctggcaata gtagaaactc atcactggta tgtaaaagaa gtatgccgta attagtatat
    40261 agtatttcct tcttcttctg tttttttcct tattaatgcg aatatgaata ttccaagaaa
    40321 aaatccaaaa aacaataaaa gtaaacacca gcatacctaa ccaaccaaaa tcagagtaag
    40381 gtcgttgaaa ccacgaaaat tcattccccg caaagttact atctccacca acatggatat
    40441 atgcgttttt aaattctggt tctataccaa acatctctac caatgaggta agactttttg
    40501 ccccccaatt caattctgga gaatatctct ggagatattt atccagcata tatactgggc
    40561 ttccgatata ataagtaata tagtctgaaa actctcttgt tgccgcagtc gagttaactt
    40621 ttgtaatacc tcttaatgca taaaatacag ccaaaatcgc tactgcaacg aataaagttt
    40681 ttcgcacaac ttgcataaca ggaactcgtc cacgaggcga tacatctgac ttcattacta
    40741 tgtatatcaa aaatactata gcaaaaagct taactaaaaa cacacggtta ccggatataa
    40801 acatacataa aatatacatt aatgttggaa acaagtattt tatatttgat aaaacacgtt
    40861 ctttgcatct aattacatta ttgataaata catacaaata tgcaaggttt aatcctgtaa
    40921 ttaaactgat gccaaatctt gcaataactg agttctgcgt ttcatctgac ttagctgctc
    40981 caattgcata taatcctaaa gtgctataat cgccttttct taatatttct accaaaagaa
    41041 caccaaagaa cacaacagat aatagtgcaa aaattaaatt taattgtctg ctagggtaaa
    41101 tttgtacata ttcaatctta tattgatttt gatggtaatt atccactctt ttttttgata
    41161 aatagtctaa gaataatata tacatttctg gtatacacat agctaagaac cccgtcgtaa
    41221 taaaccagag cgtcttcttg ctatattgca cattccaaaa ttcgatatta taaaccacac
    41281 agcatgtcgc caaaaaaaac aatgcaatcg cgataaatgc tggtgatata aaacatcgat
    41341 tagacaaaat atacattatt aaaattagta taaattcaac aatcaataat tgataaatca
    41401 tttattcttc tcctaatatt ttctttcgga gaatctccaa atattcgcat ccgaaaacca
    41461 aatctggctc catataattt ccttctcccc actcattcca agcctgaaga aatagtatcc
    41521 gatgctctgg ttccttgtct tgaacatacg aaagtgctcg gtctattgca tttccaaatt
    41581 tttctggagt actatcaaca tacactcttg catctttacc agatcgtggg gttcgatcta
    41641 atcttggaat caactgagga tgtacgcact ctctcttttc ttcttcacaa taaaaattct
    41701 ccattatctt atcatatgga tagagatttg ctgaaaaatt accaactgtc tttcgcatta
    41761 tgctcttaat acctcttttc cagtatcctg aaatttttaa ttcggcatat ctctgcatat
    41821 cagaatttat tgcgtcatat cccatatcaa ggaaacgctg aaatctatta tgcactgcta
    41881 catctgtcat agatgacaaa tcgaacttat tatcaacaga tgttactcta gccacaaaat
    41941 agataccttc aaatccattc tccttagcaa gtttattcca tagtgaaata aaatgagcag
    42001 aatctggaat agaatctgga gcaaaaacca agaataaagg tttaccatca acttttatat
    42061 atctatcatc cttcaatgcc ggaagaatag atttaaagtg aagtatatag tcttcatcac
    42121 caggatatgt ttgttccaaa aacacaacat cctttgtgaa atgctttgac ttttgccaag
    42181 ttttatttga ccatgaatga ttagcccaac cgagacaaaa aggaaagtca ggttctccgc
    42241 tctgtaacac ctcattaaat ggaagttcta gaattctctt accattgcca aaccaataat
    42301 gccaatagca aaaaccctca accccatatt tcttagccat ctcagcctgt tgttttctta
    42361 cttccgagat tcttaaatca tagaaaccta aatctgcagg aatctggggt tgataatgat
    42421 tcttgaatag aggtttagct ttagcaacat tagtccattc agtaaagcct tttccccaca
    42481 ttatatcgtt ttcacgaaca ggatgaaatt gtggcaaata aaatgccagt acccttgctt
    42541 ttttcattta actgcctcct ctaaagtaat acgatcaaac caattcagtt ttccgccacg
    42601 agttgcgtta tatattttta tgttattact ttcgcaaaac tctcttgctc ttatatatgc
    42661 ctgattcatt ccaacaatac ttgctattac ttcatttgca tttttgtctt caaaaaaatg
    42721 acttctaatg gtcttatctt cagacactgt tccatcagca ttataagtca gtgcataact
    42781 atgatccata ccaagaagat atattttttt atatcccata taaacagcag cttgaatcat
    42841 cgaataagta actgtttcat gcgatacaat ggatttactg atatcctcac taaacttaat
    42901 atttttgcca ccaacagatt gctctgagtg aatacatata gcatttggat tatgcattcc
    42961 tctaactctc caataataat ccccaatgaa catgtattct aagtcaatat catctaattc
    43021 gttaccagta tctgcatatc tatcctggat aaaataatat ttaggtctcc actgggtttt
    43081 atcaaaaatc ttaaaaataa gattagcagc aaaacaatcc ttatccttta ttaattccaa
    43141 atcctccatt gtgagacttg gaccattacc tacaataaaa caggtctcac ctaaaaattt
    43201 atttctcagt ttctcaattc tttgaatatt atctgtattc ttgcagaact tatcgtagaa
    43261 gtatttgttt tgaacatcaa ccacaaatct cattagcttt agaataggcg gaattctatg
    43321 aatcaccttt ctaattttta tatttaccat atttactcct tccgaattac aatatcaacc
    43381 aaaaattcgt tatctaatta aatgtttact atctctggcc tttctcacta atattcaatg
    43441 gagtgtcatc ttcgaagata tacccttcag ctgatgcatt acctttatat tcaccaagta
    43501 cctgtggcca ttcaatacca atctcaggat cattccaagc caagccgccc tcgtcatttg
    43561 cgtgatagaa atcatcacta gtacctttca caacgatatt cctttcttta ttaaactttt
    43621 atcaactacg ataattcaac ttttgatcga gtcctcatca atgatactct taattacatg
    43681 agtcaactga gtgctggaaa taccatctgt atggggaaga taaacaaatt caacaccggt
    43741 tcccataaac tgttcttcat atttttccta ctgaggattg cctttctaat cagaacccac
    43801 gaacattttg ttaaatttat atttctccca tgccgcatac ttatccttat cattttgagg
    43861 gacaaccata tcgacatact ttattgaatt tacaatttcg gctcgttcta catacggaat
    43921 aacaggtgtc ttatttttat cttactaaac cggttcatct gtactaacac cgacaatcaa
    43981 aaaatcacat tgtgcttttg catttcgcat aacattcaaa tgcccaatat gaaacatgtc
    44041 atatacaccc gtggtgtatt ctataacttt ttctttcata aatatctcct ttaactgtgt
    44101 atttcagagt aaaataggaa tctttctcat caatctgcat cacactctac atgtccaaat
    44161 aacatagacc gaaaagtcaa gaaagataat tttccagtct gtgatgaacc ttctctcttc
    44221 tacatacttc acatagagtt ccattcattc ttcgaaagat aaatcatttc gacgcgtaac
    44281 aatcattacc atcgaacaaa aacgttgaac cacatacaac aggcacattc ctgcggtaat
    44341 ttctttaatg ttttttctcc tgagtcttca cttaccccga tatagttaat gcgactcaaa
    44401 aaatttcttg ctttcatcgt taacctctct ttttaactaa catttcaaac aataccgcat
    44461 gttctgaagc tacccttttg gaattatact tttcaagcac taccgatgta gcttcggaag
    44521 ttagccttgc agccattgct ttatccgaaa aaatcttaaa aactgcttcg caagcagccg
    44581 tctcatcatc aacgggcacc aacaatccat tttttccatt gctaatcaaa ttgggaattg
    44641 catcaatatt ggtggcaatg ataggttttc ccaccatcat gtactcaggc agagccaaac
    44701 caaatccttc ccaacggctt aataaacatg caacatcaaa tagttcaata tagcttatcg
    44761 aattatttac ccagcctgta atatgcagac tttccaaaaa accatgttct gctgcatatt
    44821 tctcgataag tgctttttgc tctccattac caacaataat gaaatgggcc tctggtattt
    44881 tattttttac caatctagcc attttaatga atatttctgg agccttctgc ggactaattc
    44941 ttccaaccat acctacaaca aacgcatctt gtggtatatt caaactttct ctttttacct
    45001 ctccatgagc tttatttcta tatgcctcaa tgtctacgcc attaaaaatg acctgcaact
    45061 tatcttcgca acaaattctc tttttcagtg ctgattgttt ctcggcatct gatatacaga
    45121 taattttatc gcaaaacaga gcagctattt tttctatagc agtgtatagc attttcttct
    45181 taactgagca cctcatgttg aatgcccatc catgtggatt gtatacgcaa tagttcttca
    45241 aaccaatttt agcaacacgt gtaatggctc ctgctttact cgaatgtgca tacacaatat
    45301 ccggattata tttctttatc agctttctaa taattacgat tgcttttagg tcattgagat
    45361 caatttctct agtcaattta atttgcttaa atgagagcac aagatttgca taatccgtct
    45421 cgcaaaaatc ttgcgagcaa atcaatatgt tttcaaactt ttccttatcc aaatacttta
    45481 aaagcatgcg aatataacaa tctacgccac ctgcagcttg ggcaatgtgt aaaactctta
    45541 ttttttgacg catttctgtc ctccatttta cttatcataa caaacagtat atctcgaatt
    45601 accagaaaaa taatcttcca atcagcaaag aaaactctct tatactactt cacattgatc
    45661 tccatccatt ctttaaagga aagttcattt caattcagag caatctgcca ataatagcta
    45721 agatcaggct gtacatacaa ttgctgtctt tcatagcctc catactgctt catctttctc
    45781 agcaatccag atttgggacc cacgatattc atatcttcct tgaaaatatt ccaaatctga
    45841 ggagattcat catccacgaa cacgaaacga aacttataga acttgaacaa tttaccattt
    45901 cttccaactc tatcttgtgc gaaaacagga gtccgccgga tcatcaaaca caataactaa
    45961 cgctgtaatc agtatcacag gacacaaata gcaagtgtta aaatggaaaa tatgaatact
    46021 tctccaatat acccggacta gataactccc ttttgttcat aatccctcat actcatcaga
    46081 ttcaccaaac tttaccgttt atttttttca atagttcacc aaatgactcc atctaacaag
    46141 gtcaaatata aaaaattaac gcattttcat tatcttttag gcatttatta atggagatat
    46201 ttagtgtttt tataacataa taaatgctca atgagagcct atgttgggta catcaatatt
    46261 aaagtattca gcactaatat gtttaagatc gatattatat atttcataat tttgaaaatt
    46321 ttctttcata taggaaacat gatactgaat tgctttagtc acctttcttt ttttagattt
    46381 tctacaagtg attcaaaact tccataatta cagttattac ttttgaaacg ataatatgaa
    46441 catgtgtaat cttttttatc aacaatctat caattctatc ccttactaat atgccccatt
    46501 tggttttata acgatccaaa ttgtcttgat aattagttta aaatcattca atagactttg
    46561 attagttata tattctaaat ctaaatcaac cattgcatga aaactaacat catttctacc
    46621 actaacttgc cacaaacctg aacatccagg ttttacatac aagcgttgaa gatcatatct
    46681 cgtgtactca gctacttccc tttccaaagg tggacgtggg ccaactagac tcatatctcc
    46741 ttttaaaaca ttccatagct gtggcaattc atcaatgctt ttagcgcgga taattttacc
    46801 tatttgggtg acacggggat cttctttcat cttgaacatt gcgccttcta tttcattttg
    46861 atcaagtaac tcttccaatt tttcttcagc atctaaacac atcgaacgga atttatacat
    46921 tttgaatgtt tttccatttt taccaacacg tgtatggcta aaaaatatcg gactccctgg
    46981 ctcttctttt ctgattcgat aagctgcata gaacatcaaa ggagaagcta aaatcaaacc
    47041 aatgatgctt cctacaatat caatcattct tttaaaaaat aaatagatat atcgtttttc
    47101 aactttttct ttatccaacc aaacttgatt aggatgtact ttactaatac gagataataa
    47161 atcttcactt tccatacttt cagtcccttt cgctctctat tcatttcctt tttatctacg
    47221 aataaaaact aaaataaacc aaacttcttc ttttttacct cttcatatat tggataactg
    47281 atctcatccc cgttgatcag atcctttgcg acttgcttca tctgtactac tttttcctta
    47341 ccaaagtcct tggcaatctg ctcatagcac tcttttaagt aaaaggtgcg cttagagacc
    47401 ccatgggcat cagaagcagc catctgcacg agattatgtt tgaccatcgt tttggctgtt
    47461 ttctggatat ctttgccaaa taccccaaca taacttggcg cagtgagttg cgccaaacat
    47521 cccatatcta ggaacggaag caaatgattc gggtcttcgc gaaaatgcgc gttacgttct
    47581 ggatggacga tcactggtgt ctttcctagt tctaacaact caaaaaaaag ctgctctgca
    47641 tataacggca cttccagtgt cggaaattcg atcagaagat atgtatcatc taaatctgta
    47701 aataaaattt catctcgctg gatgtcttca atgagcgttc cggtaatacg tacttcttgt
    47761 ccttccaata acgtcaaagg caattgtctt ttctctaatt ctgcttgtaa cgaagcgact
    47821 agagaaatga cttgtgattt ttcattgctg tattttccat tattgtggtg tggcgtgcat
    47881 aaaatatgcg tgatgccttg ctgaatcgct ttttcagcca ttacgatact tgcctctagg
    47941 ttttccgccc catcatcgat tcctggtagg atatggcaat gtagatcgat catttctctt
    48001 gcctcctctc ttcttatttc ttaatttccg tagtaataac catcgtcttt gctgtgttct
    48061 gctccgttgt atacaacacc taggactcgt gcttgtacca tctccaacag ctcttttgct
    48121 ttagtcaagg attctttacg tgacgtattt tcacgtacca ccaataaggt gccatccgtt
    48181 tttgaagaca tgatctgtgc atctgttacg gctactattg gtggcatatc aaaaattacc
    48241 acgtcaaata actgtcttgc ttctgctagg atctgatcca ttcttggcga acttaacaat
    48301 tctgatggat tgggtggctt aggtccacta ggcaaaatcg acaagttctc gactggcgct
    48361 cgttggatca catctgctac acttcctgat gaactaagtg ctgtacttaa tccactggca
    48421 ttgttcagct gaaatgtctt atagatgacg ggtttacgta aatctgcatc gactagtaga
    48481 actcgttgac cagatttagc aaaaacgact gcaatgtttg atgcagtggt agattttcct
    48541 tctccaggac ctgatgatgt cacgacaatc gttttgattt gctgaccagt tgtggaggca
    48601 aattggatat tcgtccggat cgtacgatat tgttcggcga ttggtgaaga tgggtttgtt
    48661 aacgtgatca aactgactgc atgagttggt gttgcttttt gtttctgtgt tcgtgccatt
    48721 tttcttccct cctaaactct tgagcgactt ctgcgtgatg aggctgtttt atcgtttgta
    48781 acttttggtc gtgtaggagc cagtcctttt ttacggatac cagctttcaa ttctttctct
    48841 gacatttctg gaactgttcc taagattggg aaccctaatg tatccgtcac atatttttca
    48901 tctttcactg ttcgatcgag taattcaaat aagaatgcca gaactacacc taccatcatt
    48961 cctaacatta agccaatcac tagattcaat ttattatttg gcgaaatagg tgtcgtattg
    49021 gcaactgcac ctgaaacgat cgagatttta tcaacattca tcacgtcttt tgcattctct
    49081 tggaaaactt gtgaagttgt gttagcgatc tgttgagcag tcattgcact cgtgcttatt
    49141 gcttgaatcg agaacatttg tgaattttct gattgattga ttgagatggc atccttgatt
    49201 tgttcaggag tcattttcac gttgtcttct gttttcaaac gttcttggac ttcatttagc
    49261 actagatcac tgacgatcat atctttatac gtattgatca tttgcaagtt cgtattgaca
    49321 tcattgacat ttgcagtatc tgattgcggc agtgtcacaa tcaactgtgc ttgcgaactg
    49381 tattttggcg tcaaaatgaa aaacgttaca attcctgaga tagccaagcc agcaaacatc
    49441 gagatgatga ttgttatcaa gtgtttgcgt aatgtttcaa aaatttcttc caagctgatt
    49501 gtctcttcca ttttttctcc actttcctat ttattctcta aattcatttg ttcttttaat
    49561 tcttttttca cacgatcaag ttcattgtca ttaacttttt gatatgagat gtcatcttgc
    49621 atgaagcctt ctccttgcat ctgatcttgc ttgatcgtat caaatgcttc ccgataatct
    49681 aaagcaatct ttttcatttc atcaaagctc atgtctgttt tcatattcga ctctagagca
    49741 ttcaaaatgg attgatagtt gctgacacca tttagactca atactttttt tgctacgcct
    49801 tctacgatct ttctttggcg cccttgtcta ccgtaatcac catttgggtc ttcataacgc
    49861 atacgagaat aagataatgc ctgaaccccg ttcaatgtaa ttttaccgat tggaaagtca
    49921 tagccatctt gtgagaaagt gaggtcatta ttgacttcga taccaccaac tgcatcaacg
    49981 agttccttta gccctttcat attgatagag acatagtgat cgattgggat gtctacatat
    50041 ttttgtacgg tatccatcgc catggcagct ccgccgaatg cgtaagcgtg gttgatcttg
    50101 tcttttgtgt cacgacctac gatgtcgaca tacgtatctc gaggaatgct gacgatcgtt
    50161 gtctgtttgt cttcaggact gactgtggca accatcatcg tatctgatct tccttgatcg
    50221 acccgaccta aatctccagt atcaatcccc atcaatagaa cagagaaaga ttcttgtttg
    50281 ttcagatcaa ctggtttcgt tcgttctcct tgggttcgtt ccactgactc gtaagttttc
    50341 tcaatagaat gtgagagatc cagatataat tttgctccta ctcctacaat tgctaatact
    50401 aatacgataa gaactgctaa aataatcaga aatatttttt tccctcttga ttttcttctt
    50461 cgtcttgcca tagtttcctc cgtttgctag ctttgcttta attgttacta acttatattg
    50521 ctatagccca tttgctgagc aacagtttgt gcttttgttg cgtatgctgc gcgtattttt
    50581 tcattccgga tctgctctat ttgactgagc accgtcaaat attgatcgta agtagcggtg
    50641 gcagtcactt gaccatcctt caacatcgta tcgaataact gatctagttg cgtgacttgc
    50701 gcgatctgag tatcagcgaa tcctagatat tgcataacaa ccgttttcca aggactatct
    50761 ttaaaaaagc tcatattttc acgtacacga gcgacatctg cacttgtcac cttttctttg
    50821 atgacgacat cgtctacagc ttgctgccag tttgatacat ttttagtaaa taaatcgttg
    50881 acagctgtct ggatcttcag ttttgattct gcatcctcta actgcgttaa gactgctttc
    50941 ttttcttctt ggatcgcagc agcttcttta ggtaattctg attccttgat gtcataatca
    51001 tctgccgaaa gtttgataga agatagttta tgtgacaaat ttgaaactgt ttcttctgtt
    51061 atttcaggat ttaggaaaat tttttctttt gtactgtaca gcttatctac ttcttttgat
    51121 aaagaggtca cggtgtcttt ttgattggtg atggcagatt ctgcgtaatt gatccgttga
    51181 tgatgttgcc gctgattatt gaaatggtat ccaaacaagc aaatcacaat agcgcctgtg
    51241 cctaccgcca cagtagccaa taacttgacg aacggctttt ccatagattc actcctaaat
    51301 attgatgata gataaataaa gatgtgattc attcccatca gaatgagcgc tttttatttt
    51361 aaaagcataa ttaaactaat atattcatag aaatatttat aaacaggttt tccctatata
    51421 atcataccac aaaaagtttt cttgactagg gaaattccta atttaaaagt aaataaaaca
    51481 gtaacaagat catgattaat cgttttcatt tttatttcct ctcttttcat gagcattttg
    51541 aaaattcgaa caaagaataa aataacaaaa attattaaaa tagaattaat aacagctatt
    51601 tatatttata acaaaaaaac agagacacag cacgtttcgt gcatgctctc tgtttttcaa
    51661 acaaaagact attttgtgat gatttgatcc aagcttgcta atgacaaagc catggcagct
    51721 atttgactaa gttgtgttag tcggttctta cgtactgctg gttcatcagc catgaccatc
    51781 gtttgatcaa aataattttc gatcagtgga cgaagagcga caagctggtc gtagttttcg
    51841 tggatcgttt ggtcagcaaa acttgctttc attgcttcta ctgctttgtg taattctttc
    51901 tctgcgtcgt tttcgaacag ctcaggatct acttctgatt gtttttcaag ctgcgctttt
    51961 ttcgctaagt tcacgacacg tgtcaaagct tccattgaag gtttgaagtc ttcatctgca
    52021 agatgttgtt tgaacaattg tgctgctgca aatacttttg tcagatcttt ttgttccgca
    52081 ttcaaaacag catcgatgac atcatgacga atattcttcg ttgtcaataa ttggcgcaga
    52141 cggcctttga taaagtcgat cacttgttgt tgcccttctg ataaaccaat gccgaaacga
    52201 tccgtatctt tactgataac atcgctaatc gtttcttgca gaacagacaa aggaaaggcc
    52261 cattttttcg attcgatgat ccgaacgaca ccgtatgctt ggcgacgtaa ggcataagga
    52321 tcgtttgaac cgcttgggat catcccaaca gcaaagaaag aaaagatgct atctaattta
    52381 tctgcaatcg ctaaaacaga acctactgta gactgaggta gctctccttc actggatata
    52441 ggcatgtaat gctcacgaat cgctgtcgct acagcaggtt tctcgccttt cagcagagca
    52501 tatttttcgc ccatgatccc ttgcagttca ggaaattccc ctaccatgtt ggttactaga
    52561 tcaaatttat agatttcagc agctcgttgc agatccatca attcttcctc agatagtcct
    52621 acttgttcgc caatgatacg ggcaatgact tgtacccgtt gcattttctc atagatacta
    52681 ccgatttttt catggaaagt aacagttttt agtttttcaa cgtattggtc gattgaagct
    52741 ttcttgtctt cattataaaa gaattccgca tcttctaaac gagccgtcaa tactttttga
    52801 ttgcctcgaa ccacattttc caattttacc cgatcaccat tacgagcaga aataaaatga
    52861 ggaagcagca taccttgatc attccgtacc tcgaaataac gttgatgttc tttcatagaa
    52921 gtgactagta cttcttcagg aacagaaaga tatttttctt cgaagtcgcc agaaaagaca
    52981 gttggatatt cgactaaatt gttgacttct tctagtaaat cttcgtctag atcaataacc
    53041 caatgatttt tttcggctaa ttcattggct tgtgtaacga tcatttcttg tcttttttgc
    53101 ggagacgcaa tgacgaattg ttcattcaat ttttcttcat attcttttgc atgcgcaaat
    53161 gtcacatctt cgcctaagaa acgatgacct cgagaggctc tgcctgtttt gacatccaag
    53221 atttcgaatg ggattacttc gtcatctaac aatgccacga tccagtgaat agggcggata
    53281 tattcaaaat cgtattctgc ccaatgcatc gttacaggga aagtcaggct tttaatgaca
    53341 tctgctaaac ctgtcaatac ttctttggat tccttaccat gagtgtattt cgttacatag
    53401 acatattcca caccttttaa ttctctaaaa gtgatagcgt ctgtcgtcag accttgtccg
    53461 cggacaaatc cttccgctgc tttcgtccag tttccatctg cgtccaaagc aatttttttg
    53521 gctggtcctt tgacttcttc ttcactgtcc gcttgtcgtt ctggaatgtt tgttactttg
    53581 attgctaaac ggcgcggtgt ggaaaatgtt tcgatcgtat cataagtcaa ttggttttca
    53641 tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc ttggtgtgac aacatgagca
    53701 ggcatttctt ccagcccgat ttcaagtaat aagtcttttg ccatcttatt cagcctcctt
    53761 cacgttttct ggatttgctg tgtttttatt caacaaaggg aatcctaatt tttcgcgttc
    53821 tgccacaaag attttggcta cagcacgagc catgttgcgg atgcgagaaa gataaccggc
    53881 acgctctgtt acggatactg caccgcgggc gtctaataag ttgaatgtat ggctacattt
    53941 caagatataa tcatacgccg gatgaacaag attttcatcg atacagcgtt tagcttcttt
    54001 ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg cttacttcaa aagaatattt
    54061 agaatgttca tattctggtt gtttgaagat ctcgccatat ttcacgccat cagcccattc
    54121 taaatcatag acactttcaa cttcttggat ataagaagca agacgttcta atccataagt
    54181 gatctcagaa gttactggtt tacaaggcag tccaccaact tgttggaagt acgtgaattg
    54241 tgtgatttcc attccgtcaa gccatacttc ccaacccaca ccggcacagc ccatggatgg
    54301 gttctcccag ttgtcttcaa caaaacggat gtcgtgttct agtggatcga ttcctaaaag
    54361 gcgcaagctt tctaaataaa gctcttggat attctcaggt gaaggtttca tcacgacttg
    54421 gaattgatga tgctgataca aacggtttgg gttttcgcca taacgtccat cagctggtcg
    54481 gcgagatggc tctacgtaag cagcattcca tggttctggt ccgattgccc gtaaaaaggt
    54541 atatgggctc atcgtacctg ctcctttttc tgtgtcatac gcttgcatca gcatgcagcc
    54601 gtttgatgac caaaattttt gtaatgttaa aatcatatct tggacggtca attttttact
    54661 catctgtttt gcccctttca attttaaagc gttgctgtca aataagaata caggaaagaa
    54721 aacgacaaaa aatccctatg tctgattaca gacataggga cgaataattc gcggttccac
    54781 cctacttccg aataaagatt cggcagcttc atttatcgta ctcgcaagtg cctcttcaaa
    54841 aatcgtttgg gtccggctcc cactctcccg aactcgctaa accacgtgtt ttttactgat
    54901 cttggtcaat gtacgtattc attttgcagt tttcttgttt ctataataga tcctctcagt
    54961 gaacgatcta tttgatctac ggttaataat agacggaact ccctgtgttt gtcaaatggt
    55021 tttgattttt tgttgtatgt ttcatttact attcttcttt tttaggtaga tctttttcag
    55081 acatgtcttt ctctgacgtc tttaatacgt gtgcccaaga cttcatttga tcaatgaact
    55141 ttttgctttt caaatggata ccgacatatt catcatacag ctggtcgatg agttcacgga
    55201 ttgcttgttt ggtttcttct ttcagatgga ttccactgat tttatcataa gaaatagctg
    55261 aaaacatccg aacgaaataa acagctcgag gatctgcatg ataacggtga tcatccatcg
    55321 accagtgtct ttcgcatatc acaccaccat atttggaaga atagtcaaat tttccttttg
    55381 tttccccaca tacgacgcag tgtgtccaga ttggtgcaat tccgaagcgt tgcagtattt
    55441 ggacttcaaa aatattcgtg atgatttctg catcatctcc ttggtccatc cgttgcagtg
    55501 cttgttgcgt aaactggaac aaatgcgggt cgtactgatg atcttcgatt gccgcatcta
    55561 ctagattcaa taaatatgtg ccatagccgc tcaaaaagat gtcttcttgg atgtgtcgaa
    55621 acgcgtggac atctttgaca ctgcttaaaa atgacaaacc ttcacttcga aaattcccga
    55681 tataaactgc ttcagtaaaa gggagcaaag ccggagctaa gggctgattt tgccgatgga
    55741 tccctttgat ataaaacatc attttgccag aagattccgt aaagattttg actaatttat
    55801 ctttttcttt gtaattacgg ctagataaaa tcaagccttt tgattctgca agctggctca
    55861 tattctccct cctaaaaaat aaatctggaa aagcagattc tgccgatcca gatcatttat
    55921 gttgcgatct tccgcagctt ttctcaacac gcggattttt atccagttta tttctatacc
    55981 taacttacaa gaagctcaga atatcaatat tcgtcttttc ggtagccgaa gtcttgcaga
    56041 tagacttttt tgtctcgcca gtctttttga actttgaccc aaagttctag aaagactttg
    56101 tctcctaaaa gattttcgat atcttttctc gctttcgttc ctacttgctt cagcattttt
    56161 ccgcctttgc cgataatgat ccctttttgg ctatctcttt cgacaataat cgtagcctgg
    56221 atatggattt tatcattctc gtttcgcttc atcgaatcaa caacgactgc gacagaatga
    56281 ggcacttcgt ctcgtgttaa aaacaagact ttctcacgga tcaattcaga aacgatgaag
    56341 tattcaggat gatcagtcac ttgatcatct ggaaaatatt gtgggccctc tggcatttca
    56401 ctgactaata catccatcaa acgttcgacg ttgtttcctt ctgtagcaga aattggaatc
    56461 acttgtgcaa acggcatctg cgttgaataa tcttcgatga ttcccaacaa ctcgtctgga
    56521 tggattttat cgattttatt gataatcaga taaacaggag aatgcacgtt ttttagacgt
    56581 tcaataataa aatcgtctcc ccgaccgcgt ttttgatcag cgctgatcat aaataagacc
    56641 gcgtccactt ctttcaacgc actgtaagct gcttctacca taaaatctcc taaacgatgc
    56701 tttggtttat ggattcctgg tgtgtcaata aaaatcaact gagcttctgg tgtagtatat
    56761 actccttgga ttttatttct agttgtctgc gccttatcac tcatgatggc aattttttga
    56821 cccacgattc gattcaataa tgtggatttt cctacattcg ggcggccgac gattgcgaca
    56881 aaccctgatt tatgttctgg catatacgtt ctccttttta attaaacaac aaatgatata
    56941 ttttagggac aaataaaatc aacccaacga tgacggaaaa acaagcggtc actaaaactg
    57001 ctccagctgc catatctttg atttttttcc caatcggatg aaaatgaaaa tccgtaaaca
    57061 tgtccacgac attttcaaaa acagtattga tgatctctac tatccatacg agaaaaacag
    57121 ctaaaagcag ccataaccat tctatccgat caagctggaa aatcacgccc ataaacaaag
    57181 cgaggattcc gaacgcaaca tgtttcctca tgttgcgttc ttcctcaaaa acggttttga
    57241 ctccttggac ggcaaattcc acggacatca ggaaatgttt gtttttctct acgtttttat
    57301 cttttaagtc cataggcatc taagatctct ttctgtaaac caaacatttc tttctcatcc
    57361 tctggtgtca tatggtcata cccgttgata tgcaagaatc catgaaccgc taaaaagcca
    57421 agttcccgat catacgaatg gccgtaagct tctgcttgct ctgcagcacg ttcagtagag
    57481 atcatgatgt ctcccagtac acgaggcaat ggattctctc catcttcaaa aatcactggg
    57541 atttcgtctt cgccctcttc ttccaaggca aaactgatga cgtctgtcgg tgcatctttt
    57601 ccacggtaat cacgattgat tacttggatc gctgcattgt ccatgaaagt aacagacatt
    57661 tctgtttctt ctggcaactc taaatatgat gctgcaaatt gcagcaagtc gtcgatttct
    57721 ttcattttct cttctgagac ttggtttgtt tcatccatga aagtaatatc cattatacat
    57781 cgcttctttc tattcttctt gttcttcttt tatcttctca acttccgatt tcattttagg
    57841 atatttgatc cgagaatgga aggtactgct taaaccgctg atcaatgatt tttctacttt
    57901 acggatttct tttaacgtca atccactgtc gtccaattgt ccatcggaaa tacgctcttc
    57961 aataagatta tggacaaaac tttcgatttt ttcgctcgtt ggatggtcca ttgctcgtac
    58021 tgccgcttca caactgtcag ctatattgac gattcctgct tcacggcttt gaggttttgg
    58081 tccaggataa cggaattgct cttccgtgac ttccgggttg cgttcctttg ccttaacgta
    58141 gaaataacgc atcagcgtgg ttccatgatg ctgtctgcaa atatcgatca ccatttgcgg
    58201 catattataa tcttccaata ttttggcacc atctgtcaca tgtccaaaga taatatgttt
    58261 actgtcttct ggcaataaga aattgtgcgg attttccgct cctgaaggca agttctcaac
    58321 gaaaaagctg gcgtgtttga tcttgccgat atcatgataa tagcaagcta ctcgagttag
    58381 taaagaacgt ccaccgattt ctgctacagc attagcactt agattggcta ccatcatgct
    58441 atggtgatac gtgcctggtg cttcttccag caactgtttc aataaaggat gattaggatt
    58501 gctgagttca tttaatacga tcacactatc atcattgacc atcaattcaa tataggggtg
    58561 cagacctatc gtcagcaaga atgagaacag tgcacctgtg aatccgcata ctagcgttaa
    58621 ccaagtcgtt gcatccccaa agctcattcc ttggtagata atcaaaatga catccatcat
    58681 cacaggaaaa ataatgaccc acatagcagc ggataaccct tgttctgaga tccgtttgcg
    58741 tctgacgatc gttgccatga gaccagaaaa tacataggac atcaaaataa ctgtcagaaa
    58801 gttcgtgcca atcgaatcat aaaaaatgaa aagtgcggat actgcttgaa aaataccagc
    58861 catgatccct gctcttcgat tcaagaaaaa gcttaaaaca agtggagcaa aagccgcggg
    58921 gtaaaacagc ggaatataag cagcttgttc tgtttggaag agttggaaaa atttcattag
    58981 tacgacgctt actgacattg ccgtcacgta gaaaagtacg tattttgttc tttctcctgc
    59041 attttggaat tgaagtgaat tataaatcag tacaccgatt tgaagcaaaa cagctaaaac
    59101 catggcaatg agtgggaaaa tagaagtcgt ttgattcgtc aatcctagta attccaattt
    59161 tttcatcgct gaagcatcaa tttgatttcc ttcgcgaaca ataatttctc cttggaagat
    59221 catcactggt tgtacagctt ctcgtgcaga ttgttttaat tcttctgtct ttttctcatt
    59281 caatacatca ttaactacaa tgccttgatc cactaagtag cgaatcattt gttgctgctc
    59341 tgttgtgaca ttcaaatatt gaatctgatc ttctgcttct tgtttaaaag cttccaattc
    59401 gctttcacga acttgtttac tcatctgttc gtcaatgagc ttcaaacttt catccctaac
    59461 cgtgtgaatt tccgtttcag tcatttcaaa tatcgtcgaa taaaaattgt tcggcagttt
    59521 ttggtaaaac gcaacgtttt ctgcattcac gttttcaaaa tttttcttca gtgtagcaat
    59581 ccgctcttct gtagtaggtt tcgggatatt ttcatcttcc ttcgccttat ctaccttgtc
    59641 attataagat ttgttgatgg tatcattcgt cttatcgatc aattcgaata attgcttgat
    59701 ccgattgttc tggtcatctg ccagatcttt ttgataagta tattctggag tcactgcttc
    59761 tgctgccagt tttcttcttt gttcggtttc ttccgtgttc tcaatcgttt tattcgcacg
    59821 gatactctct tctgctactt ggccttctct gaaatcattg gccttttgtt tgacactact
    59881 aaatgtaacg ccgcagacaa tgataaaaaa caagaacaga aggaaaggca atgctgcctt
    59941 tccgagtttt tcttgtagtt tctgcagtgt tttattcaac atgtgcttat cctcctaagc
    60001 aaagcttatt cttgatgaag atccgccttt tcataagctt tgatgatttc ggcaactaca
    60061 gggtgccgaa caacgtcact tgcttcaaaa ttaacaaaat cgattttttt gatttgcttt
    60121 aatgttcgtt ctgcatgaac aagaccactt gtcgtcccac gaggcaagtc tatctgactt
    60181 gtatccccat tgacaatcat ttttgattga taaccgagac gggtcaagaa cattttcatc
    60241 tgagcgactg tcgtgttttg tgcttcgtcc aagataacga atgcatcatc caatgtccgc
    60301 ccccgcatgt aagctaaagg tgcgatttcg atcacgcctc gttccatcaa tcggttcgta
    60361 tgatccaatc caaaaatttg gtataaagca tcataaacag gccgcagata aggatccact
    60421 ttttctttca gatccccggg tagaaagcct aggttttccc ctgcctccac agcgggccgc
    60481 gtcaaaatga ttttttgcac ttcgcctttt tttagggcag caattgctaa tactacggca
    60541 agaaacgttt tccctgttcc ggctggccct acaccaaata cgatgtcatg tttggctacc
    60601 gattcaacgt atttcttttg accgctgttt tttacccgta taggttttcc attacggtct
    60661 ttgacgatct cttcctcata catctcaaca aaataatcta atgtaccttt ttgccccatc
    60721 ttcaatgccg tcacaacatc tggcgtactt acgtggattc ctcgtttgat caattcctgt
    60781 aatgtccgaa tgactgaggc agccaaggaa atctgggatt gctcaccaat gatctgaatg
    60841 atttctccac gtgtatggat ggttgtttcc gttgtttcct cgatcagttt tatatgcttg
    60901 tcgtgtgcac ctaaaagcat gctgacatca tcagcagctg tcaatctaat ctctaaagaa
    60961 ctagactctt ccgtcaaaaa tagacatccc ctttttttcg attcattctt tcctatttta
    61021 ccatactcag aagaaactat atagcaaata agaaaaggtt gtaaaagagt cgtttaacca
    61081 tacgtaccaa gaaacgttaa aaaatagccg tttccattcg ctaaaggtct cgttttgata
    61141 aaaagaagct gagaatgtaa gttatatgaa agtggagaac aaaatattcc gtttcattca
    61201 gcaggtattc tctaggtatt tttcttgttt caaaaaaaga aaacaaaata gttaaaatat
    61261 tcttgcattt caaaaaaaac aggtgtatta ttacgtcaac aaataaacat acagcaaagc
    61321 gtcgaggaaa acagtaggct attcaacgat ttattcccag tgagtcatgt aagtgagaaa
    61381 tgacaataaa tcgaatagac gaacatcatt tccgagtcaa tgtcgaaaac gtagatcatt
    61441 gtggctgcct ccattatcag gctagcggat aactttatca aaaagcgtcc gtgaatgaag
    61501 aagctttttt aagcgaaaaa aggtggtacc gttctagaat ctagagccct tttcccaagt
    61561 ggaaaagggc tttttttata ttttaaggtg gtggttttca tggaatctga tattagtggc
    61621 attactaatt gctgcaacgt ttatatcgtc aatcaaaatg ataattattg gaggaaaaat
    61681 ttatggaaga aacaaaaact tattcatgga aacaactatt gatggtcagt tcacttatct
    61741 tcgggatgtt cttcgggtca ggtaatctaa tctttcctgt ccacttaggt caaatggctg
    61801 gcgcaaactg ggtcagtgct ggcgtaggat ttgccatctc gggcgctctt ttcccattac
    61861 tagctatctt agctgtagta gtgacaaaaa gtgatggtct gtatgactta gctaaacctg
    61921 tcggaaaatg gtatgctgcc ttgttcttaa tccttgttca tttgacgatc ggaccatttt
    61981 tcggtacacc acggacagct gctactgctt ttgaaatggc tgctaaacca tttttgcctg
    62041 aaaaatataa ttcattaggt atgtttttat tctctgctct tttcttttta cttgcttatt
    62101 tccttactgt ccatcccaca cggttggtca aatacgtcgg aaagtatcta aactccttgt
    62161 ttcttgcatt gttagcaatc atttttgtcg tttctttatt ccacccaatg ggaaatctaa
    62221 atcaatctgc tgcagatact taccaaacaa acgctttaac aaatggtgtc ctagaaggtt
    62281 ataacacggt tgatgcagta gccttgcttg ccttaagtgt cacttttgtc catgcagtcc
    62341 gtgaccttgg tttcaaagat aaaaaagtca cagaattaac agcaaaagct ggtagcctga
    62401 gcgttgcgct agaagtcatg atctattttg gtcttgttct tctcggtgcg atgagtttga
    62461 ataagatgtc tttatcagaa aatggcggaa ctgcactttc tcagatcact aatttttatt
    62521 taggtaactt cggcgctagc ttcttaggag tgatggtcac attaggtgtc ttcactaccg
    62581 ctatgggact cgttgtttct tttgcgcaag atttccataa actgttccct aaagtcagtt
    62641 atatgacatg gctgcggtta acgactttcg tctcttttgt cgttgcaaat gctggtttag
    62701 acaatatcat ccaatggtct ttaccagtat tgatgctttt gtatccattg tcgcttgcgt
    62761 tgatcttgct ttccttaaca gcaaaatttt tccaaaagac accatttgtc tatcaagtaa
    62821 cgatgttgtt tgctgctgtt cctgccgtat tggatatgct ggcaaattcg cctgctttag
    62881 tgagtcaaca aagagttgta gcaagcatgc tcgaatttta tcatcatcac gttccttttg
    62941 ctgcattagg acttggctgg atggtcccaa cgttacttgg ttacgctggc agcctactgt
    63001 tttattacgc ctatcgccta tcagggtata aacaagaagc aaatgaacta ccagaagaat
    63061 aaccaaatca aacacaattt aacataagaa atattaaaca ggaaaaaacc agctagatga
    63121 aagaatccta ttctttcgtc tagctatttt tttgttctct tttttacgcg cacaaaaaaa
    63181 ctgcggacaa tgattgtccg cagtttaaat gataaaatta agattgtaat agttctttca
    63241 caatggcatt tacttggttt ccatctgctt ttcctttgac tttaggcatg atcgcaccca
    63301 tgactttgcc aaattctttc attgatgaag caccagtttg tgtgattgct tcttgaacaa
    63361 gttgtcgaat ttcttcgtcg gaaagttgtt ccggcatgta tttttcgact atcacaattt
    63421 cactttttac tttttcagct aaatcgtcac gtcctgcttc ttcaaactca tgcaaagaat
    63481 cacgtcgctg tttcatttcg cgagacaaca ccgttaattc ttcttcttct gtcaagtcgt
    63541 gaccttcttt aatctgctcg ttttgtatag atgacttgat cattcggatg acttgtaaag
    63601 attccttatc tttcgctttc atcgctgttt tcatgtcatc gtttaatcta cttagtagtg
    63661 acacactacc aactccaatt catcacagaa ctagaatttt ttgcgttttc tagctgcttc
    63721 agattttttc ttgcgtctta cacttggttt ttcgtagaat tcacgtttac gagattcttg
    63781 taaagtaccc gcttttgaca cggaacgttt gaagcgacga agagcatcgt caagtgattc
    63841 gtttttgcga acgactgttt ttgacatgtt aattccctcc ctccgagctt aaaaagtaac
    63901 cgtaattgtt attgaaatat atctcaaaaa acaagactgt cctgtaaata ttatatctaa
    63961 tgctgttttg accgtcaagg aaatcttgct tttttttaaa attatcaaat gttattttat
    64021 ttaaatcctt attgacaatt ttcacatctt ccgaaaatct cgaatctatg cccttcgatc
    64081 gtacatccac cgagctgttc ttcgaaataa ttcattggac acatatggat ttctttcgtt
    64141 gttccgcaca ccgtacagat aaagtgatgg tgatggccga tttccccttg acagcaatga
    64201 aaacgaaact tcatctctcc atttaaatcg gtttcttcca gtaaatcgat ttctgcaaaa
    64261 tcatggagat ttcgataaat cgtatcgtaa cttactcctt tgaattcctg attcatatag
    64321 tcaaaaactt ctttagcgga tacgtagcga ttgcgcttca ctaaataagt taacaatgct
    64381 tctctttttt tagtatattt aaaaccgtta tttttcaatg tttctagtga ttgttcaatc
    64441 aatgtctgtt ttttcatgac ttattcctcc aaatcaaaat gattacgaag tacacattct
    64501 agagtatggt ataataaaca taaaaaaaat gcaagtgagg ttttatccat gtcttccgat
    64561 tctacagaaa tcgttacttt ttttgtcatc tctgactctg ctggagaaac tgcgacaaaa
    64621 ttagcgcaag ccactatggc ccaatatcct accgttgagt tcaatttatt ccgcagaaca
    64681 tttgtgacag atgagaaaac attgatgcag gcactgcaag atgcactaaa agaaaaagcc
    64741 cttgtcctgc acacattgat caatcaagaa ttgatcgaga tgacgcgttc tttttgtgaa
    64801 gaacatcaat tatttagttt tgatgtgatg actccgccga tatcagaaat cgagcgctta
    64861 actggtatca agcccattcg gcaacctggc gcccttcatt tattgaatga gaactatttc
    64921 aaacggatca aagcaatgga atttgctgta aaatacgatg acgggaaaga tcctcgtggg
    64981 tttctagaag cagatgtcgt tttgctaggc gtatccagaa cttccaaaac gcctttgagc
    65041 ttgtttttag ctaacaaaaa tttaaaggtt gccaatctac ctttgatccc acaagcacat
    65101 attcccaaac agctttggga gatcgatcct aaaaaaatcg tgggactgac gaataaccca
    65161 gatattttaa acaatatccg taaagaacgg atgcgctctt acggattaaa tcctgatact
    65221 gcttattccg atatcgaaaa aatacgagct gaactcgatt ttgcgaatga tctttatgaa
    65281 aaattgggct gcgtagtaat caatgtcgct tctttatcta tcgaagaaac agcttcactt
    65341 attttgaatg ctttagacct agaagatcat agttattatg gaactgaaac caccgaagaa
    65401 acagactaac agtttttctt gtctttttct taaaaaaact ggactgtgtc agcgaagaag
    65461 attcgttgat acagtccagt ttgtctctat ttgcacctat cgttattgat gttccacatg
    65521 tttgagcgtc tggttcaaaa tatccagtac gtgagaatca tcaagactat acaaaatcgc
    65581 ttttccctca cgatgggact tgacgacatg gttttctctt aataaacgca gttgatgcga
    65641 tacagcagat tgttccattt ctactgcttg ggtgattgct gtcacatttt gttccccgtc
    65701 tttcagatac agcagaattt tgagacgagt ggggtcactc aacattttga atagttggct
    65761 gactttctct acttttgttt tttgcgtgtc tggcaatcca ttcacctcca acttgaaaaa
    65821 agactgactt ctaaagttta ccactttttc catcagtctc aagttttttt attcttctgt
    65881 catttttttg ataatcgctt cataagcggc tactttttca gctgcgtctt ctgaagagtt
    65941 tccttttaca ccgatataaa atttgatttt cggctcagtt cctgaaggac ggatagcgat
    66001 ccagccattt tcttccagcg tatacttcaa tacgtcagat ggcggtgtcg ttagtttttc
    66061 tacgtttcct tcacggtctg ttctcgtcaa ctctttgaag tcttctgttt ggatgacttt
    66121 tgctccggca aattctgtcg gtgcttcttc acggaatttt tccatcaaag cagagatttt
    66181 tgcagaacct tcttgtccgc tcattgtcac agaaatcgtt ttttctgcgt agtagccata
    66241 tgtttcaaaa atcgtttgca agccgtcata caacgttttg ccttgttttt tatagtaagc
    66301 tgctacttct gctaataaga gcaatgcttg aatcgcgtct ttgtcgcgaa cgaaaggttt
    66361 aactaaataa ccgtaacttt cttcgaatcc gaacataaaa gtatgggaat gatcttcttc
    66421 aaattgttga attttttcag cgatgaattt gaatcctgtc aatacattga acatggtagc
    66481 cccatagtgt tccgcaattg ctgtaggcaa ttcgctagaa acgattgatt tcaataccgc
    66541 tgcattttca ggtaaagtgc ctcgcgattg gtgtgcttcc aaaatatatt gagcaaacag
    66601 ggctccgatt tggttccctg tcaatacttc ataggagcca tttggcaaac gaacggctgc
    66661 gcctaaacgg tctgcatcag gatctgttgc aatcagtaag tcagcgcctt ctttctcgcc
    66721 aagtcgcatc gcatactcga aagcagagtg ttcttctgga ttcggtgatt tgactgtagt
    66781 gaaatccggg tctgcgacag cttgttctgg aactagtacg aattgttcga atccagcttg
    66841 tttcaacgca cgttcgccca acatttttcc tgttccgtga agtggtgtgt acacaagttt
    66901 caaatcttta cccattgttt ccaccaattc atgatcaatc gttactgctt tgatttcttc
    66961 tagataagcg gcatccactt cttctccgat gatcgtgatc aatccgctat gttcagcttc
    67021 gtcgtcagat aatacttcaa cttttaacgg attgctgact tcacggacat atttcgtcaa
    67081 tgcatctgcg tctgcaggag gcatttgtcc cccatcttct ccgtagactt tatatccgtt
    67141 gtaagctgct ggattgtggg atgcagttac catgattccc gcaaacgtct tcaaatgacg
    67201 gactgcaaaa gaaagctctg gtgttggacg taaactttcg aatacataag aagggatatt
    67261 gtgatgtgct aatgttttgg ctgcttccat ggcaaattct ggtgattgat ggcgtgagtc
    67321 ataagcgata gcgacacctc ggcgttttgt ttcttcacct tgtgtatcca tgaaacgtgc
    67381 aagtccttct gttgcttgtc ttaccgtata gatgttcatt cgattgatcc caggtcctaa
    67441 gattccccgc atgcctgcag taccgaattc caacggtgca taaaaagcat cttcaagttt
    67501 ttcaggatct tcacccagat caattaattg tttttttaag ttttcttcta aattttcttc
    67561 atgtacccat tgttcataca cttgttccca agacatgaaa ataacacctc tttctgaaat
    67621 atggttctta ataagtatag cattcactta ttagatatga aagtacgagg tctaaaaaac
    67681 gcttaaatca agaaaggatt cttttatcaa gcacggttgc aagtattcgc ataaatcgga
    67741 ttcagtagat ttcacgcgaa aaaaaagagt aaaagaacaa ttgaaaccgt tcttccactc
    67801 tttttaaact tatgcagttg tttcttctaa agattccaag tatttataca cttgttgtcc
    67861 agcgatccca ccatcaccaa cagcagtagt gatttgtcgc aaatcttttt cacgaacatc
    67921 tccgatggca aaaacgcctg gtatattcgt cttcatttcg ttgtctgttg gaatccagcc
    67981 agcttcgttc gtcaaccctg cttctctaaa tggtgcagtt aatggatcca gtccaacata
    68041 gatgaatact ccgtctgctg ccaaatcaaa ctcattgccg gttttgacat tacgtgcttt
    68101 cacacctgtc actaccattt cattcccaac gatttcgtca acgactgtat cccacataaa
    68161 ggaaattttt tcattcgcaa atgcacggtc ttggatgatc ttttgtgcac gtaattcatc
    68221 tctacggtgg acgatgacta cttcagaagc aaattgtgtc aaatagatgg cttcttctac
    68281 tgctgagtct cctcctccga tcactactag acgtttgtta cggaaaaacg caccatcaca
    68341 aactgcacag taagaaacgc cacgtccagc aaattcttcc tcgccaggta cgcctaattt
    68401 acggtggata cagcctgttg cgataatgac tgtttttcct tcgtaagttt tatcttcaca
    68461 aataacttct ttgtggctgc cgtgatcctt gatatcttgc acgattccat aagcattttc
    68521 tgtcccaaat cttgaaacac cttcatacat cttataagct agatcaggac ccatgattga
    68581 atcgaaacca ggatagtttt cgatttctgc cgtattgttc atttggccgc caggggcgcc
    68641 ttgttcgatc atcaatacgg ataagtttga acgtgaagca tataaagcag cagtcatccc
    68701 agcaggacct gcgccaataa cgattacatc atacatatgt agattctcct ttacttaatc
    68761 aagtaagcat actttacagc caatgcgaaa aaaagtctat tgttctgctt gcgtttctcg
    68821 aatagcttta ttatactcga aaaatccgct gaaaaacaat agacttttac aaatcattga
    68881 tcaatcattc gaaagatttt ctccatttga atcaattact tttttatacc agttgaatga
    68941 tttcttcttc gaacgggcta atgtgccatt tccttcgttg tcacgatcga cataaatgaa
    69001 tccgtacctt ttcttcatct cacctgtacc agctgatact aaatcaatac atccccaagt
    69061 cgtatagcct aatagatcga ctccatctaa ttctactgta tctttcattg cctggatatg
    69121 tgctgccaga tagtcgattc gatagtcatc ttccacataa ccattctcat cgggcgtatc
    69181 gactgcacct aagccgtttt ctacaataaa tagtggtttt tgataacgat cataaatatc
    69241 attcatcgtt attctcaagc ctaatggatc aatttgccaa ccccattcac ttgcttccag
    69301 atatggattt ttgacagaag caaagatatt tcctgcagtc tgttccaaga gttcgttgtc
    69361 agtagtcgaa actcgagaag aataataaga aaaggagata aaatcaacag tatgttcttt
    69421 cagcaatgcg gcatccccag gttccatttt gatctgaatg ccatttcgtt ccatttcttt
    69481 caatgcataa gcgggatatt ctcctcgtga ctggacatca atgaagaaat aattttctcg
    69541 atctgatttt ctagaagccc aaacatcttc aggattgcaa gtgtatggat aatatgctcc
    69601 tgctgccagc atacagccta ctttgttctc cggatctact tcatgagcaa tcttcgttgc
    69661 gatggcactt gcaaccaact catgatgtgc cgcttgatat ttgatttgtt cttcattttc
    69721 tccttcttca aaatacagcc ctgcgcccat gaatggtgca tgaaggatca tattgatctc
    69781 attgaatgtc aaccaatatt tgacaagtcc tttatagcga ttgaagatga ctcggcacag
    69841 attttcataa aaaccaacga gttctctaga acgccacgca ccatattctt tgatcaaatg
    69901 catcggacaa tcaaaatgtg taatcgtcac aagcggctcg atcccgtact tttgacattc
    69961 tttaaagaca tcctcataaa atttcaaacc agattcattt ggctcatttt catcgcccat
    70021 tggaaaaata cgactccaag caatggacat ccgataagtc ttgaacccca tttctgcaaa
    70081 caaagcaata tcttccttat aatgatgata catatcgatc gcaatttttg ctggataaaa
    70141 atgatcttta tcaaattcaa acattttctt ttttccagta atgacaggaa aacggtcttc
    70201 tccgattggc acaacatcta cgttcgctaa cccacgtccg ccttcatcat aaccaccctc
    70261 gcattgattg gctgctgtag caccgcccca taaaaaatct tttctgaatc ccatcatact
    70321 tcctccatta catgtgtatt gcttgacaat tctcttgcca gttcatcttg gacttcgatt
    70381 ccttctgctt ttaaccggct gattgtttcc ttgaattgcg gtaaatactg ctgatgtgca
    70441 ataaacaact catccatgat ccgttttgct gtctttcctg atcgtataag cggattgatc
    70501 gtaaacgctt gtaaagctgt tccataatca ccagtcacgg ctgcttcgat cgtcagcaat
    70561 tccatattct tcattacttg caaccagcct ctttcagcag caggaaggga accaaacgct
    70621 acatttcgtg cgccttgtgc gccaacatag gcagtgactt ctactacaca atctgccggc
    70681 agatcaggaa cagctccatc attctttgta gacaccacga tctgtgtttc tttatttcca
    70741 tagatcgaag caatcgtttc acaggcagca tctgaataat aagcaccacc tcgtttttgc
    70801 aattgttcag gtttatgatc caattctgga tctttgtata attcaaacag ctctgcttct
    70861 gtttctttca cttgttgcgc tcttgtacca atcgtttgat attcttctaa agcatgttcc
    70921 aacatttctt cttcacggta gtaatagcgg tggtagccac aagggatcat gttcatttgt
    70981 tttaattgtt ctttgaaaaa cgggatgtca aagatatttt tcggcaatcc attgtcttca
    71041 tcgtataaac gatcaatcaa atctgctgtg cggtcatttc ctttattatc tgctactttg
    71101 tgccaatgga agtgatttag accggcaaac ttgtagatca gctcttcttt tttcttgcca
    71161 agcattgctg gttctgtcat cgtcgccatt actggcacat tgcataatcc gatcacttta
    71221 tcccatttgc catatctgat aactgcttct gtcaccatcc cgcttgggtt cgcgaaattg
    71281 atcagccaag catttggaca taaacgcttc atgtcttcaa cgattgccaa aaccactgga
    71341 acggtacgaa aagctttgaa tatcccgcca gcaccatttg tttcttgccc aatcatccca
    71401 taataactag ggatccgctc gtctttgatt cgtgcatcta attgaccgac acgaaactga
    71461 gtcgtaacaa aatccgcatc tttcaatgct tcttcccgat ccaaagttgc atagatcttg
    71521 acttcatacg gagaagcatc ccacatacgc tgagacatct gactgacgat ctcaagcttt
    71581 tcttttcctt cttctacatc tacgagccag atttctcgta tcggtaattc ctcatatctt
    71641 ttgataaatc cttccatcaa ctcgggggtg taactgctgc ctccaccaat cgtagcgatt
    71701 ttgattcctt ttgccatgtt ctcactcctt tgctttttac acttttatta tcttttttgt
    71761 aaacaaaaca aacaatagaa attcgtttct ttccagtaac atttacaaaa gttagtgttt
    71821 tctactggat ttttgtaaat atcttgtcaa aaaatgactt tattaagcta tataacataa
    71881 atccgtttac aaatcatttt caaaaaagtt ataatttacg taaaaaaact agaagaaggt
    71941 atctacatgt tattacgtga aaaaatcaaa gaaatctcct tttctccttc agaaaatgaa
    72001 gtgattcagt ttctcttaag cgattctcca gcacttggcg aaatgaccat ccaagagatt
    72061 gctgagcgat gttatgtcca cccgtccaca ctcatccgtg tagcaaaaaa aatgggtttt
    72121 gatggctggg tcagttttcg taatgctttt ttagctgaaa cagcctatct tgaagggaat
    72181 tttcaagacg tagatgcgaa tcttcctttt tccaccacag acggtattat gacgatcgca
    72241 aataaaatgg cttctttaga acagatgacg attcaagata cactttctct cattcatcat
    72301 gaccaactgc aaaaagccaa acaactaatg cttcaagcaa aaaaaatcgt gattttcgcc
    72361 agtaactcga atactttgat ttctcaagat ttcatgctga aaatgaagcg catcaaaatg
    72421 gatgtcacga ttgtcaccac ttttggtgaa tcgttctatg aagcgtacaa ttgcacgagt
    72481 gatatgtgcg ggattctgat ttcttatacg ggtgaaaaca atgtgatcct tcgtaccgca
    72541 gaaatattga aacaaaatca tgttccaatt ttagcgttga ccagtatcgg tgattcaacg
    72601 ctatcctcaa tgagtacagc cgctttgcga cttacgacac gcgaacgact gtattcaaaa
    72661 attggtaatt ttacgatcaa tacatcgatt tgttatcttc tagacgtgtt atatagttgt
    72721 gtttttgcag aaaattatca acagaattta gtccatctaa tttctgtagg acaaaaattt
    72781 gataaacgcc ctatcagctc agccatcatg aaagagcctt tcaattttga aaataaagaa
    72841 gtggactaaa aagaatagtt aagtctattc cattctttca cctaaccgtt caggtcagtg
    72901 cggtgataag tgcatcgtct ggcccgaccg tctccccttg attttccaaa atatccaaat
    72961 aatccatgta attggtgacg attacaggtg tttctaaact gtatccttcc ttttcgattt
    73021 tctttttgtc gaagcggagc aacagatcgc cttgtttcac tctttctcct tgctgcacca
    73081 agctttcaaa atatttccct tccaactgaa cagtatccaa tccgacatga atcagcaatt
    73141 ccagacctgt ttcagaaacc attccgattg catgtttcgt ggggaacagg gtcatgactg
    73201 ttccgtcaaa aggggcacgt acttctcctt tttcagggta gatcaagatt cctcgaccta
    73261 gtgttccttg tgcaaaagct gcatcctttg ctgctttcag tggagcgatt tgtccttgta
    73321 tcggtgtttt tacaatttct ttacctgatc ttttctgtct gtcatctgtt tcacctgctt
    73381 cctccttcca aaagaaaaaa gtcagcgcaa aggataccac catcgcaatg gcgatcccaa
    73441 tcaatacatt aatcacatct gttaaatcac catctggtct aatatagttg ggaattgtaa
    73501 agatgcctag tccaccttga ttccaagaag ttaaattcat taacccacta tacgcgcccc
    73561 ctaacgcacc accgacacaa gtaaaaataa atattttttt acgtggtaat gtaaacccat
    73621 aaatagctgg ctctgtaatc cccacaatac cagaaacaat ggctggtatt gcaattgctt
    73681 tgtcttttgg atttctaagc ttaaagtaga gtgcggtaag tgctgcagtt tgtccaaaag
    73741 acactactgc aacaggtgtc ataatatttt gccaaccatt cacagaaaat tgcatcaatc
    73801 ccattggtac gattgcccaa tggagaccaa acatcaccag aatttgccag aagaagccta
    73861 cgattgctcc ataaataact ggcgaaagtg ctaaaagtgt ttcaaatcca gccattaaaa
    73921 tatcagttgc gaatgtgaat actggtccaa cgagtaaaaa acctaaaggc attgtaataa
    73981 gaacggtgaa gaatggaacg aagaaattcg cgatcatctc aggtactaac tttttaattg
    74041 gtttctgaat ttggctagct aacaacacaa taaagataat gggaatgaca gaagaagcgt
    74101 agttacgcgc aatccaggga atgccgaata ctgtttgata aataggtgct tcaaaaatag
    74161 tgccagaaaa tatggtcgtt agtggtgctt ctgctgcacc actcaaagct tccagcgaca
    74221 agctaggatt cattaatgct gcgccaagca acatccctac gaattcattt actttaaatt
    74281 tacgggcagc tgttaaaccg ataataacag gcataaattg gaatacagaa tcaccgatat
    74341 tatcaaacat aacaaatgtg ccagaaccgc ggtcaaacgc gcctaagaag acaaggaatg
    74401 ctgtcagtcc acgaatcatc ccgccagcag ctaagatagc aaggaatggt tggaaacagc
    74461 ccgatattcc atcaataagc atatcaaacg gtctcatttt ttctgttgaa acagcctcat
    74521 caaaagtaag gtttcctgct tttataacct cttcaaacac gactggcaca tgattcccga
    74581 tgacaacttg atactgccct cccgctcgca ttaccgttac aataccgtcc atatttttca
    74641 agatctcatc atttgctttt tcttcgtttt ttaatttgaa acgaagcctt gtgatacaat
    74701 gtgtcaaacc attgatattt tccttcccac cgacattttc tacgattttt ctcgctaatt
    74761 cttggtattt tcccatttct attccctcca atatattagt ggaaggttta gccaactgaa
    74821 tgtcactacc cttatttcat acgttcttgt taatttatcc tccttttttt atttatttac
    74881 aacgattctc atgcactaaa cgcgcagtat ggatcgttaa atacattttt tcgtccgtgg
    74941 acatctggta gttgaacgtc tcggctaaaa agtctgctat tttctcaacg caaccaaacg
    75001 tatccttata ttttttttga ataacctgaa acaattcctc agaaacttct cccacttctg
    75061 atttttctcc atctaggacg cgtgtcagaa aaaaacgtaa gtgtgtgacg aatcgaaaaa
    75121 aatggactga atcttcatca aatgtaatct tatagtaata gcggacgata tttagaatat
    75181 cctgtattgt tatagtaaac aggtaggtat tgttttgttg gctttgaatg ccttgtgcat
    75241 tgactaaatg caatgcgata aatccggctt catcttctga taacttgatg tggtatttat
    75301 ccgagatttt cttcactgtt tttttcccga tggcatactc tttaggaaat agttgtttga
    75361 tatcatacag caatacattt ggtacaaata ttcccatttt gtgacgttcg atagccgtat
    75421 acaaatgatc cgtcaatgca atatacacag aatcattcaa ctggacttgt agagcctctt
    75481 ttgtatattc aatgatttca caagaaattt ctaagtactc aagaggaatc gcttgtgcca
    75541 attcttggaa ctgttgtgaa agcccgtcat ttgtcaactg aaattttttg tcgatgcatg
    75601 agtcaaaaat cgggtcaccc actttctttt tgaatgccaa accttttccc atcacgatca
    75661 tttcctgatt tctttcatcc ctggttatta cgacgttgtt attcagtact ttctcaatca
    75721 gcatgttttg ctcctttcca tgatatatag ggctgtattc aaaacaaaaa gaaaaaccca
    75781 aaaagccgtc catggaacca tgggagactc atcaggttta gcttgcatca ggcaatcact
    75841 atccaagttg tatcgttttc tttatattat cgaaagcaaa cgctttctta gtggctatta
    75901 ggcacttttg actagctgtc gtcgtctttt ttaaatcggg tgactacgcc actaacgctc
    75961 acagatgaag aatctgggaa gctctgtttt attttcactc tagcgcttag gacaaaatgc
    76021 tactatgcta ctgtcacaac ctctttttac acaccactgc tttgcagttt gtacatatct
    76081 gcatacaaac cattttgcgc tagaagtgtt tcatgattcc cacgctctac tatatgacct
    76141 ttgtctaaaa ctaaaatcaa ttctgcatcc cgaatcgtgg acagccgatg ggcaatcgca
    76201 atcgttgtcc gtccttgtcg catttttgcc aatccttctt ggatcaatcc ttcggtttca
    76261 gtatcgatat ttgctgttgc ttcatccaat actagtattt taggatctgt cacgattgtt
    76321 cgcgcaaaag tgatcagctg tcgttgtcca ctagaatagc tggcaccgtg ttcgatcact
    76381 tttgagtgat atccttttgg taattcatcg atgaacttgt ttgcttgaac aaactcagct
    76441 gcatggcgaa tctgttcgtc tgtgatagct ggattcatca tccggatatt tcctgcaata
    76501 tctccataaa acaagaaggc atcttgcaag accaatccca ttttcttacg taactcttcc
    76561 attggatatt ctcgaatgtc atgatcatca atcaagattt ggccttcata aaattcgtaa
    76621 aaccgcatca atacgttgat gatcgagctt tttccgcttc cggtgtgccc cactaatgca
    76681 acggtctcac ccggattagc gacaaaagag atattgttca atacattgtg ctctccatca
    76741 taagaaaagc ttacattgcg aaactcgatc ttacctgaag taatcgcttg atctgctcca
    76801 ggattttgtt gcggtgcata ttcttctgta tccatgattt tcaaaatacg actaccggca
    76861 accatcccat ctgtaaaggt gctcaaaaag tccatcattt gagacattgg attaaaaaat
    76921 ccctggacat aggtcgtaaa tgcatagatc agtccaactt ctacgggaga atgcaacgca
    76981 tcgatcccaa acaaagtcaa cgccaacgca atcgccaatg catagagaaa attgatgatc
    77041 ggacttaaca gaatcgaatt cgttttgatc atcgcatagc gcgtgtctaa atactcgttg
    77101 ttcacttgtt caaattcttt agctaaacga gcttcttggc gaaactgctg gataatacgc
    77161 atgccggaaa tcgattcatt caatttcgtg ttcagctgac ttaatttttc ccgcatattt
    77221 cggtaaatac gagaactgaa tttctggtaa taccagatga cgattcctaa aatcggcaag
    77281 aacaccaaag tccacaaggc aatttctcca ttgatttgaa acatggcaac gaaagaagaa
    77341 acgactgcaa agatcccagt caataccatc aaaaagacat accaaaattc aaatagcgtt
    77401 tctgtgtcat tcgtcactcg agaaacggtc gatcctgccg gtgtctggtc aaaataacgc
    77461 atacctagtg tatgcagctt ttcaaataat cttacccgaa catactgata ggtcttcaat
    77521 gaagccatgg aatacaaata ccattggaaa aaccaaatga tacttttgac tatgactcca
    77581 aacaagtaca caccagcaaa aaacaaaata acttgtgtcg tagctgactg tttagccaga
    77641 tgatcatcca taaaagtttg gatgatcctt ggcaatagga cattgatcac agacagggca
    77701 aacgcaaata agatagcaac gatgaacgtt cttctaaaag gtttggcgaa cttcatcagt
    77761 cgtttgatga tcttcttctg ttctttaagt ggaatcgatt ttgtccattc cgattgataa
    77821 ttttcatcca tcaggcctcg cctccttcta tcttcgcttc taattgctgt ttttcccaca
    77881 ttcgttcata ccagccacct aatgcaagca gctcgtggtg ggttcctcgt tcaatgattt
    77941 tcccttgatc gacaacaatg atttcttttg catgcatcac gctgcttaaa cggtgagctg
    78001 caatgatggt tgttttctct tttcttattt cttttaaatt atgcaagata gcttcttctg
    78061 ttttggcatc tactgcagaa agtgcatcat ctaagatcag caattcagga tttttgatca
    78121 atgctcgagc aatcgaaatc ctttgtttct gtccgccaga taaagagact ccacgttctc
    78181 caactaaggt atcataacct tttggcaatt ccttgatttc attgttgata aatgctaaag
    78241 aagccgcatg ctctacttct tcttctgaaa gttttggatt agaaaaacgg atattatctc
    78301 gaatggtcat cgaaaacagg aagtgatcct gaggcacata accgattgat cctaataaag
    78361 cattcaatga atattctttg atcgaacgtc cgccaaattg gattttccct tgataatcat
    78421 cgtattcacg catcagtaat ttgatgattg tcgtttttcc cgcaccagtt ttcccaacaa
    78481 tacctaatgt ttctccttct tggatcgcaa atttgatttg ttctaatgct ggtgattctt
    78541 ctttcggata gttaaaagag gaaatagcta cattcagctc gccttttgcc ggggtctgca
    78601 ctgcacccag ttgttccacg atatgcgtct tttcatgcaa aagttcatta acgcgatcat
    78661 aagaagcatt tcctctttcc aatacgttga acaatcggcc aatcgcaaac atcggccaaa
    78721 caagcatacc gatataacta ataaatgaga ccatctgccc aatcgagatc gtgccttcca
    78781 agacatactt tccacctaaa ataattgttg caacataaga cagaccgata atcaaggtaa
    78841 tgaatggatc aaataaggag tctaaaaaat tgactcgttt gtttttaata attgcatctt
    78901 caatcttttc ttcaaaatcc gcgagatctt ctttttcttg tccaaatgtt ttaatgactt
    78961 tgatcccagt gatactttct tgtgtcttat cattgatact agaaaaagct tcttgcgaat
    79021 cacgaaaagc atcgtggagt tttgacccca gcactcgtga agtaacggct agcaaaggca
    79081 gaggaatcag cgcaatcagt gttaagcgcc aatcaataaa caaaatcatc gcaatgatcg
    79141 ttgttccgcc cgtaatcact gaatctgcaa aggtcaagat tccagctcct gctacattct
    79201 ggattgcatt caaatcattc gttgcatgag ccatcaaatc tccagtccga tatttttggt
    79261 aaaagagatt gtccatttct gtaaaatgtt tgaatagctg ctgccgaagt tctttctcca
    79321 accgagctgc acttccccaa atattcgtcc gccagatata acgaaaaaga tattgtaaga
    79381 aagctgcaag gatcaatagt aagatccacc aagaaatgat ctttattgat aaattcttat
    79441 cggcgatctc atcaatgatg atcccaatca cttttggagg aactaactgt accaaggcca
    79501 ctgcgaatag ggagaaaatc ccaattaaat aatgtttctt ttcctgacga aaaaaccaac
    79561 ctaattttct aaaaatcgac attttactcc tcctttgtct ttatcaagag cataggattg
    79621 tctgtccttg tcttttttgc tgaatagtct gaatagtcta acaaattacg aaataaaaaa
    79681 cggactgaaa aaatcagccc gcaaaaagtc tttgggtcag aacctatttt ttcccttggt
    79741 tcttcatttg ctgcatcatc tggcgaattt tcttctcaga tggtttttgc cccattgaca
    79801 tcatcattga tcgcaacatg tcctcattaa cgggaggatt tttttctaaa tagtctttca
    79861 tatatttacg cgctaggaaa aagccaccta ctgcgccgat tagcaaagca ataatagcaa
    79921 taagtacgac aatacctgtt gataccatat aaatctctcc tttctatttc cgaattgctc
    79981 tcaatgattt attttactaa agtttattga aaaaagaaag gcgtattctt tagtttcatg
    80041 caaaaaatag tggttttttt agagaagaac aaaatttctt tcattaacca gcaagacacg
    80101 ccacgaaaaa aaattaggca taccgaatct ttttctttaa ttttttcttt ctgaggtgta
    80161 gaatgtaatc gtagataaat aggaaaggtg gttttttctt gaataatcaa tccaacaaac
    80221 aatttcataa gcatcgactt attgaacata caaatggttt atctttagct gaagtaaatg
    80281 gaacagtgga tgtaccaaag ggaaaaagtt tttttaaaac acttcttgct tactctggac
    80341 caggtgcatt agtagcagtt ggttatatgg atccaggtaa ctggtccact tcgatcactg
    80401 gtggacaaaa tttccaatat ttattgatgt cagttatttt gatgtctagt ctaattgcta
    80461 tgcttttaca gtatatggca gcaaaattag gaatcgtgac ccaaatggat ttggcccaag
    80521 caatccgagc acggacaagt aagacattgg gtgtcatttt atggatcttg actgaattag
    80581 ccattatggc aacagacatc gcagaagtca ttggtgcagc aatcgccctc tacttacttt
    80641 ttgatattcc attggtaatt gccgtattta tcactgtgtt agatgttttc gtccttttat
    80701 tgctgacaaa agtcgggttt cgtaaaatcg aagctttggt tgtctgcttg attttcgtca
    80761 ttttattcgt tttcgtctat caagttggct tgtctaaccc tgattggcac agtttatttg
    80821 ctggctttat ccctaacagt catacattct cagactcacc tgtcataggt ggtgaaactc
    80881 cgctgactgg agcgttaggg attattggtg caacagtcat gccgcataac ttatatcttc
    80941 attcagcagt ttctcaaact cggaagatcg atcaccaaga cgaagaagat gtagcacaag
    81001 cggtacgctt ttctacttgg gactctaata tccagttgtc aatggctttt ttagtcaatg
    81061 cactgctatt gatcatgggt gtcgctgtat tcaaaaccgg ttctgtccaa gatccttcct
    81121 tttttggtct gtatgaagct ttatctgatc catcagctat gagcaatggt atcttgattg
    81181 ctgtagcaaa atctggtatc ttgtctactt tatttgctgt agcacttctt gcttctggcc
    81241 agaactctac tattactggt acgttgaccg gtcaagtcat catggaagga ttcatccata
    81301 tgcgtatccc gatttggcta agaagactag tcacacgatt gctttctgtg attcctgtat
    81361 tgatttgtgt tttgtttaca agtacaaaag gaacgatcga agaacatacc gctttgaata
    81421 acttgatgaa tgaatcccaa gtttttctgg cttttgcatt gccattctcg atgattcctt
    81481 tactgatgat gaccaatagc caagcggaga tggggagccg attcaaaaat tcatttgttg
    81541 taaaacttct tggctggttc tctgtgatta gtctgactta cttgaactta cgaggattac
    81601 caggtcaaat cgaaagtttc ttcggcgagc aagccacctc agctcaacta gcattggctg
    81661 atcaaatcgc ctatgtaatc attgttcttg tccttctcct gttggcatgg acgattggtg
    81721 atttatataa aggaaacaaa aaatatgaac agcgtttgca agaaacgata gaagaaatcg
    81781 aatagaaact gattctttta cacaaaggag gttgtgacag aagtgggcag cttcaagaaa
    81841 taagaaggaa tttaagaaaa ttgcttttca aatttttgtg aaatttcggc ttatttccga
    81901 agaagttact tctggaacac cgtgtatcag aggttgtgaa aaagctgccc tgcatcaagt
    81961 aataagaaca gccaaacaaa aatagttcct catattttac gtttggttga gcttattacc
    82021 gcagatgcaa gcttttgagc accgtttatt cggaaaaagg aactgcgaca agacttttgt
    82081 cacagttccc tttttatttg gaagataaag cttttttcag attcaattta ctaaaaacta
    82141 gcatgcttgt tactgcgatg aattgcgtta atggcacgcc tgcgccagtg tagacactta
    82201 aaaaataatc ctttttttct ggcgcataag aacaaaacca cgagacaccg aaaagaaaaa
    82261 ccaattgtgt cagtattaat ccgatgacta caatcaaaga ggaactataa taggcacgat
    82321 cagcttttgc aaatacggtt cctagtatca taagtaatat ccctgctatt gaagcaatca
    82381 gcacgggaat ggccagaact tggtaaattt ttatcatgac attcgcgact tttgctgttt
    82441 ttgtcaactg gaaatcaggt gttctcggat cactgctatc gatccaatta tccattagtg
    82501 gaagattcaa taattcttgt gcctgttcga cttgttcttg cgtcccaaaa ctataattcc
    82561 ccccttgatg gaaatctttg tatcgccatg cataagcata tcctgatttc agaaaatcaa
    82621 atacgattgg cagatcattc atcgtctttc catcccctga tcccatcaga tagaattctt
    82681 ttttcttttt gatagttccc ttttgatagg cttcttctaa ttcttgattg acttttttcc
    82741 aaaaatcatt ggtttctttt gcattgtttt ggtaataacc agattcgctt accacatctc
    82801 gcaatgccca aaaaatgata tctcctggta attcttttac ttttccgcct tgggtccacg
    82861 catgagtcgt atacaattcg tcaatacgag tagaaacagt atgaaatgta ggagatgcgt
    82921 ctaaagcttt atttaatgca gcatgcgaga cccatatctc actgttttct ttatttaagt
    82981 ttgtttcgtc atctattcgg atcagctgtt tcatcaaacg tccaaattcg ccactcgaac
    83041 ggtcattgat ggctgcaata ccatatgttg tctcgttttt atattcgatc cactgataga
    83101 cgatggagaa accgactaga gggagtaaaa acaatgaaag tttcagccat tcttgtttcg
    83161 aaaggagaaa tggtcgttct tttaacttct ttgcttcttt gaaagaaaag tcttgtccta
    83221 gcaagatctg aacgaaactg atgcctaacg cgactacagt aaaaggaaga agccagatgg
    83281 aatcttcgcg aatgaaccaa aagaaaggaa aagaaacagc tagccctaaa aaccacggca
    83341 gcaatttttt gctggaatta tatttgcggt aataaatagc tagtaaacaa gcgataatga
    83401 tctcaacagt cgggatcacg agagcattac gatatgttcg agtggaatat tcatgtgtaa
    83461 aactaatcgg agaaaacaaa aaataaaaat agatacttaa aagaagatac ttgttcttca
    83521 cgattggttt aaacgctagt gcaaccaata tactggcaag aatactgaac atgccgaata
    83581 aaactgcata agaaagatgc agtttatgtg caagtactaa aaacaagctg taggaaatcc
    83641 cttttgaaag tgtcgtagtc gtgtactccc ctagccattt accatccaaa atattttgag
    83701 catagtgaat cagcagctga tcatcatagg tcgccgacat atctgttcca tagattgctt
    83761 tactatataa atacaaccga ataattgtaa ataatacggc tatgccaaga ataaagtatg
    83821 tatgtttctt ttttagttgg tcgatcaagg ggtttaaaat gttcagcatc ttttcgtcct
    83881 ttcaatcacg ttttgctact tgtttgtgaa acttttcgtt ttttactttt ctatcagtat
    83941 accctgtttg tctgaattta aaaagagggg gcaaaaggag catggcgaaa acgaatgcaa
    84001 aaagcactcc tttgtttctt aaacaaaaaa ggacaaggca gactgcccaa tccttttttg
    84061 ttgctgtcag gtagaaaact taaagtgtga cttcttctgc taataactca gggaacactt
    84121 cgggatcgaa tgcttgcgct ttgaacatgg aaatttcttt tccatatggt gcgtaagctt
    84181 tctttttatc tttaccgaca tatggggttt ctaatatttt cgaaatgttg tcaaacattg
    84241 gatcatggac gattttgttc aatgtgtcaa atccaattgt tccaaaaccg atattggcat
    84301 gccgatcttt atgagaacct tgaggatttt tagaatcatt gatatgcagt actttaagcc
    84361 gatctaatcc gatgacctta tcaaactctt ccattacacc tgaaaaatct tcttttatat
    84421 tatatccggc atcattcgta tgacatgtat caaaagtaac ggataatttt tcattcaatt
    84481 ttactccatc gatgatttgc gctaattcct caaatgttcg accgatttcc gtacctttcc
    84541 ctgccatcgt ctccaaagcg atctgtgccg tctgttcttt tgtcaaaact tcattcaacc
    84601 cctcaataat tctagcaatc ccagcttctg cccctgctcc tacatgagcg cctgggtgaa
    84661 gggtgatttg agtagcacct aaagcttccg cacggacaat ctcttctctc agaaattgta
    84721 cagcaaatgg aaacatttct ggtttgatcg tatttcccaa attaatgata taaggcgcat
    84781 gaacgacgat atttgttagt ccgttttctg ccataaatgc ttttccggca tcaatattca
    84841 tctcttcgat agcttttctt ctagtatttt gaggagcgcc tgtatagatc ataaaggtcg
    84901 aagatccgta actggctgct tcttctgccg cgcctaacag cattttcttt ccgctcatgc
    84961 tgacgtgtga gcctaataac atggatggat tcctccttga aaggcaattg tttcgaacaa
    85021 ttcctgtata ttgataagat gatgtacaaa gaaaatagtt tgtttttctt tgccctgttc
    85081 tccatagtaa ctgaaacttt ccctaaagaa aagcttaaga actctttcat aaaaaagatc
    85141 atttcctcac gttttatctc attcgaaaaa gaaattcctg tcaaaaacag ccttgtctgt
    85201 ttttttgtcc tattatttgc tataattagc gaaataaaac cattagttga ggtgaccctt
    85261 ttgccacgca aaaatactcg aaaaaaacag aatagaagaa aaaaagaaaa atggtttgtt
    85321 cctaagatta tttttagagt gtttcaatca ttgactgttt ttattactgt tcttcttttg
    85381 ttgttcgcag ctctaggtat cggaataggt gctggctact ttgcctatct tgtcgaagac
    85441 acacaattgc cgactaaaaa agaactgcag acagaactag gaaacattac ggaaacgtca
    85501 aagattgttt atgcagataa tacagagata tcaaaaatcc agacagatct gatgcggacg
    85561 actatttcat ctgataagat ttcgccttta ttgaaaaccg cgattatcag tacagaagat
    85621 gaatacttcg ataaacacca aggttatgtc cctaaagctg ttttacgagc actagtttca
    85681 gaagcgactg gcatcggctc gtctggagga tccactttga cacagcaatt agtcaaacaa
    85741 cagatcctaa ccgatgaaac aacattcaaa cgtaaagcaa acgagatcgt tctttctgca
    85801 caagtagaaa aacacttttc aaaagatgag atcattacta cgtatttgaa tgtctcacca
    85861 tttggtcgga ataataaggg gcaaaatatt gctggagtcc aggaagctgc tagaggaatc
    85921 tttggtgtag atgcaaagga tgtgactctg ccgcaagctg cttatatcgc tggtttgcct
    85981 caaagcccta tcacgtatag tccatacacg aatacaggcg cgctaaaaga agatctttct
    86041 gccggtcttg ccagaaaaga ttttgtttta ttcagtatgt accgtgaagg acaaattacg
    86101 aaagaacaat acgaagaagc gaaagcctat gatcttacaa aagactttct cccacaacaa
    86161 atcgcggaac agactgacag agaattcttg tattataccg tgatgaacga agcaacaagg
    86221 attattgcac aacaattggc agaaaaagat aatgctgata tgtcagattc atcggtcagt
    86281 gaagcttatt atcaaaaagc acagcaaacg atccaaaaca aaggatatac gatccattcg
    86341 acgattgata aagatatcta tgctgcattg caaaccggcg tagaaaatta tggctacatg
    86401 ttagatgatg gtgctggtag ccaagtggag actggaaatg tattgatgga taacagaacc
    86461 ggacgtatct atggcttcgt gggtggtcgg aattacagcc agaatcaaaa taaccacgcc
    86521 tttgatacag aacgtcaagc tggttcatcc atcaaaccgg ttcttgttta cggtcctgca
    86581 atcgatatgg gacttgtcgg atcagaatcc cgtgtatcag attatgcaac gacttggcaa
    86641 gaaggaaaaa atgctggtga gaaaatcgtc aatgcgacca atgaagggtc gaacaccttc
    86701 caaaccgtcc gtgagtcact ggaatggtcc aacaatatcc cagcttatca cttatatcaa
    86761 gatgtgttga attccggtgg atcgaaacaa tacgcttacg agcactactt ggcgaagatg
    86821 aactacccag caaatgataa ttggggcgtt gaatcggctc ctttagggac agtagatgta
    86881 acgacgcttc aacagacaaa tggattccag gccttagcaa atggtggagt ctacgaagaa
    86941 ggctatatca ttgattccat cacagataat gcaggtaatg tgatttataa acatgaaagt
    87001 aattctgtcc gtatttattc cgaagcaacg gcatcgatca tgaatgacat gatgcgtagt
    87061 gtgatcaatg aaaaaatcac tacaccattc aaagatgtca tctcaagctt aaacggaaat
    87121 ctaggaaatg cagattgggt cggaaaaact ggttctacca atgaataccg agattcatgg
    87181 ctgatcgtct caactccatc tatcactatc agtagttggg caggacacga tgacaatact
    87241 ggaatggaca gccaagcaag aatacgttcg gctaattatc ttgccaatct aatcaatcaa
    87301 gcttaccaag caaaccctga gattttcggc actgatgaga aatttgactt atcatccgat
    87361 gtgatgaaga aaaaagtatc tgggttcaca ggacaaacag ctggaaaagt tactgtcaat
    87421 aaaaaatcta tccaaacgcc aggaaaaaca gtggaatcac tttgggcaaa aaatggtccg
    87481 aagaaaagcg cctttaaatt cggcgttggc ggtactgatg aaaactatac agattactgg
    87541 aacaccgctt cagcttatgc tagagcgaat ccagagacca aagaatcaga cgataaagat
    87601 gattgatcta atagattaat cagaattaaa gggagctgcg acaaaaatct tgtcacagct
    87661 ccctttttcc gaataaatgg tgttcaaaag cttacatcta cgatattaag acaaatttat
    87721 gtaaaaatgt gaaaaaccat tttcacaaaa tttttctata taactttact aacgaaactg
    87781 ttttaatttc ttttcttgtc tttggaataa ttcggttagt ttttctgcaa attgcccttt
    87841 tactgattct tttaagtgtg catgtcggtt agaaaattct tgagtagctt cttctgcagt
    87901 catttggtgg ttttgatctg tcaatcgttt ttctgcccaa gtttgctgag atatccccat
    87961 accaactgaa cgtacatttg atcgatgtag atttttctct aattctttta gtaattgcat
    88021 taaaaattca ttcataagat gatttctcca tagttatttg tctgattttt tgacgatagg
    88081 aacgttctag ttcgtcttgc tgctgataga gttttcgtcg ttctacttgt agggcttgtt
    88141 gataatgctc ctgataattc gaataacttc gtcttgcttg aaacagaggc tcattatcta
    88201 aagctaagtt ctttaataca tgatgcagtc gctgctcctc ttgctccatc aatcgtaatc
    88261 cttgattctt aaagtggatc aattcatctt cttgagcttc taattgtctt cgttcacttc
    88321 gataatctct ttccaattct tctagtttca tctacttctc ctttaattga attgctgtgc
    88381 taattctcga tctcgtgcca cgatttcatt gattttgtct tggatctcct tcgccaatgt
    88441 atcaaaggcc tcccccatac gtcttgcctt attgattcgt agcagataga cttctttcgc
    88501 agaatcgact aagttctctt ttgtggcgcc cacactagct aatgcttcta tgatttcctg
    88561 ttcagtcaac gaaggggcga caacacgtgc ttgccgcaag ccttcttgcc attttttctc
    88621 tagctcaaaa attcctcttt ggttgatgcg gataacttct tccatagcgc ttttcatttt
    88681 taccgataac ttttccacca ctaacctagc ttgtgtgtca tctaagtaaa tttgttcatt
    88741 aactgtcagc cggccgccac ttaatcgtag ttttttacgt atgttgttca gttcttgcaa
    88801 ctgataggaa aacaactggg tcgcttggtt ttctttctgt tgttttcgag ctttaacatt
    88861 gttttcattt tcaggaataa tcagctttcc attttcatca aacttccaag aggttaaact
    88921 gtgggaagca agcagattca agtatgctgt ttccatactg atccgaactt cagcacctgt
    88981 gccattacca ccaaaattac cgataaaatc ggcgtgattt cggtaattgg tgagcatacc
    89041 gggattttct tccacccatt tttttgcttc tggtgataag agatcatacg ggtccggccc
    89101 gttgaagccg acatttttcc attgtttctc tgctgctaca tataatgcta agaatccacc
    89161 taatgaatgg ccggtagtag aaatagcagc ttctccatat tcctttttta cttcattagc
    89221 aaatgcaatc gctgaattga tttgccccgc tgttttcaat ccactaacgg ataaaatctt
    89281 gtttgttgtt gctttttcag aaaaacttgc tcctggtcta ttcccataga gattcataac
    89341 acttcttgca tccgtttcca aatctttcca atcgcttaag ttcgttcctg caaaagcaat
    89401 cactacttga gaaatatcca ctttaccgtt cttgattggc gctacagcca tcgcctgcat
    89461 gccgtcgaag gagtttttga tttttaggat ttggaatttt gtttctccaa agtttttaat
    89521 ggcgccttct ttgtaacttt tactatattg aggatgtttt ggatctagcc aatatacttt
    89581 attacttatt cctttatact gcttatcagt aattgtcata ctttttcctc actcccatct
    89641 gtatagataa ctataatctc atcaaccgta atcccttctt tttgtacttc ttcattttca
    89701 acaccatagc catctatctc attgctttct tttgtaaagc tataatcaaa ataaacggct
    89761 tttccttctg tattggtcat cgttatcaat gcttcataga ttcctgtcat gtcgtttttc
    89821 tcaaattgtt cgattttcac ttctttgata tccgcaaagg tatttttcag aactttgacg
    89881 gactgttttt ctactgcgag taaatcttgc tgtttttgcg cttctctttt gtccatgtaa
    89941 aattttcctc cgattcctat agtaagaatg gtcaaaatga tgactatggt ctttcgtctt
    90001 ttcttaggca aatagaagtc tcctttcggg ttatgtatga tggattgttt ctcctttaag
    90061 ataagtacgc aatcgagcct ggattttttt ggatttttta gagttacttt tctacttttc
    90121 tactttcttt tttatcacgt tttcatttta aagtaatttt gatagtagtg aacaaaatgt
    90181 agcatctacg cacagattgt gtcgtatacg atggacgtaa ggtttgtttc cgccattctc
    90241 tctttttttt aaagtcacaa aaaaaggggt tatgacaaaa ttttgtcata accccttttc
    90301 tcgtataaag gttgttccag aagttgacca ctttgggaac aacctttaaa tgattgatct
    90361 tttattattt agttgatcct ttttcttcga ttccataagg caagataatc gttttttctt
    90421 cgacttcttc tttattcatc attttcgtca ataggcgcat ggataccgct cctaaatcgt
    90481 ataatggttg tgtgatactt gtcaaacgag gacgagctac ttctgtcagt aaagaattgt
    90541 tgcttgtgat gatttcgaat tcttctggta cttttacgcc gcggtctaat aaaccatcca
    90601 agataccaat ggctaattca tcgtctgaaa catagacagc tgttgcaccg ctattatgga
    90661 tccggtcaac tagagacaga ccatctttaa agttgtattg tgcctcaaaa atcaatcctt
    90721 cgctatatgg tagattgttt tcgcttaatg cttctttata gccttttaga cggttttgac
    90781 cattgatagg atcaatcagc gcaccgctga caaaagcgat ttttttattg ccgctttttg
    90841 ctaatttatt tactgcatct tttgttgctg atacataatc aatgtttacg ctacctactt
    90901 gttcatctgg atcaatggaa ccagctagta caacaggcgt ttttgaacgt gaaaattctc
    90961 cacggatttc gtctgtgata tggtgaccca taaagatcac gccgtccact tgcttagcca
    91021 ataaattatt caatacattg acttcttttt gatcgttgcc atctgagttt gctaagatga
    91081 tattgtattt gtacattgtt gccacatcgt cgataccacg tgctaaagag gcaaagaaca
    91141 tattgctgac atcaggaatg attaccccaa ctgttgttgt tttcttactt gccaagccac
    91201 gtgcgactgc atttggacga taatccaagc gatcgataac ttccaagact ttttttcttg
    91261 ttgctggttt gacgtttgga ttgccattta cgacacgtga aacagtagcc atcgaaacat
    91321 ttgcctctct cgctacatca tagatagtga ttgtttgctt ttccatttgt gttctcctat
    91381 tcatatttta tatgttttct gaaaatacgt cttacatttc taaaatagga tatcaaataa
    91441 tctcaacaat tgcaaccgtt ttatctctgt tttcatgaaa atttttactt ttttcagttt
    91501 taagaacgtt ggtcttttaa tcaatcagtg gtacaattat tgaatacaaa attaatttag
    91561 aaagtaggtt gccaaatgaa taacgtaaaa atcaatgaac tacgtcaatg gatggcacaa
    91621 caccaattag aattggctta tatcagcgac cctggccaca tcgcttactt ttccggatat
    91681 gaaagtgatc ctcacgagcg tgtactagct ctttttatcc ctctggaaca agatcctttc
    91741 cttttcactc ctgctctgga agttgaagat gctcaaaaca gcagctgggc gtacgatgta
    91801 cgtggctact tagacagcga aaatccttgg gagatcatcg gaaaagagct tcgcgcacgc
    91861 tatgggcaac ctggtaatgt aggtattgaa aagaatgctc tgactgtcga tcgcttcgat
    91921 gctatctctg atatcttgac aggtacagat tcttacaccg atctaacttc tattatccag
    91981 cgtctgcaac tgatcaaaac ggtagaagaa aaagacaaac tgatcgaagc tggtaaatgg
    92041 gccgatgttg cctttgaaat tggcttcaaa acagtaaaag aaggcgtaac tgaacaagca
    92101 attatcgcag aaatcgaata ccaattaaaa aaacaaggtg tttcacaaat gtctttcgac
    92161 acattagtcc ttgcaggagc aaatgctgca agccctcatg gtacaccagg aagcacgaag
    92221 gtttcaccaa atgaactagt gttattcgat cttggcgtta tttggaatgg ctattgcagt
    92281 gatgctactc gtacagttgc ttatcaaaaa ccaactgaat tccaagaaaa aatctataac
    92341 atcactcttg aagcacagct tgccgcacaa gaggcagttc gcccaggtgt gacagcaggt
    92401 gaacttgatc aaatcgcacg aaacgtgatc aacagctatg gctacggcga atatttcaat
    92461 caccgtttag gtcacggaat cggaacaacc gtccacgaat tcccttctct tgtagaagga
    92521 aacgacttag tgattgaaga agggatgtgc ttctctcttg aaccaggaat ctatattcct
    92581 gaaaaagtag gggtacgtat cgaagattgt gtgtatgtga caagtgatgg ttgtgtgcca
    92641 ttcacgacta caccaaaaga attacttgtt ttagagtaat gaaaataaaa aaggtgagag
    92701 ctggtccgct ctcacctttt ttattctaga aatgagtaat cttagtgatt ggtagtcgaa
    92761 tctgtcattg tatctttcat ttctttttta gcttcttttg catcttcttt tgcatcttct
    92821 tttgccattt tcaacatttc ttttgtgtca tctgcaactg gttttgcttc tgacattcct
    92881 tcattgaccg tctctcctgc tttatctgca gcatctttta catcgatcat gatatcttct
    92941 gaagtatctt tagcaatact acctaattcg tctgctggct ttttcagatc ttctgctgtt
    93001 tttttgaaac gattagataa atcagctgat tgttctttga ggtttaacaa gatatcatct
    93061 gattcgcttc ctgcttcctc tgctgattca cttaccttct gcttaacatt gcctgctaga
    93121 tcccctgctt gttgagaaag atcttgcgct ttttcttttg caatacctgt taactcagat
    93181 gatttttctt ttgccatatc tgtgtaatct gaagccatgt ccatcaaatc atctgcttga
    93241 gcagccaatt catcccgaag ttctttacca gatttgggtg ctaacaataa tgcggcgatt
    93301 gctgcggctg tacctccaac tactgcacct aataaaaatc cacctttttt agccattctt
    93361 attttcctcc tgtcgtttca gtatgttttt tgtttttaaa aatttcatcg ctgttccacc
    93421 gacttttccg gcaacagtcg ctttagctgt cgtttttccg attccgccga ctttcgtcac
    93481 gatgttttta ctagaatgat taagttccga tacactttca cttaaatcag caactgctgt
    93541 gaacaatgga tcgatcgttg cgacttttcc attgatatcc aagagcagct cattactttt
    93601 gactagcaag ccttctactt gtctagataa aagatctacg tcttgtgtga cgatctcaat
    93661 tgtcgtattt gcttctgcga cagtctggtc tactttttct aaagttttgg aaacttgcaa
    93721 caatacgcga acgatgaaaa cgacaagtat cgcaaaggcg attgctgcga tcaatcctgc
    93781 aatttctcct cctgacatga tcaaactccc ttcttgtctc tcttttctat aaggatagca
    93841 ttttcgtgtt ttttaaacaa ataaaaacga gcttcaacta ctttttattc aattagcagc
    93901 tgaagctcgt tagaaaaaaa gattattttt tcttttcttc tttgatttct gttattcctt
    93961 ttggattatg attgatcttg cttccttctg cttctaatgt tttacctaaa gacatgatgt
    94021 attcacgcaa aggtgcccct acttctggat gtgtcagacc atattcaata cttgttttca
    94081 taaaaccaaa tttgtcacca acgtcataac gtttacctgt gaatttacgg gcaaatacgc
    94141 gttgtgtttt attcaacgta tcgattgcgt cagttagttg gatctcattt ccagcgcctg
    94201 gttgttgttc tgataataca tcaaagattt ctggagtcaa taagtaacgc ccaataatag
    94261 ctaaatcact tggtgctttg cttggatctg gtttttcaac aaagtttttg acattgtata
    94321 acccatcttc cagtacttcc cctgggttga tgattccgta ttttgaagtt tcatcgtgag
    94381 gaacttgcat aacggcaatc gtagaagcgt gtgtacgctc atagtcatcg atcaattgct
    94441 gtgtcaatgg tacttcgtct tccatgatat catcgcctag cataacgaca aacggttcat
    94501 ttccaataaa ggctcttgct tgaagaacgg cgtgtcctaa cccctttgga tgagattgac
    94561 ggatgaaatg caaattgaca tctgtcgttt cttctactaa tttcaataat tcggtttttc
    94621 ctttttcact taggtttgtt tctaattcga tatttgaatc aaagtgatct tcgattggtc
    94681 gtttagcttt tcctgtaacg atcaagatgt cttcgattcc tgatttcaac gcttcttcaa
    94741 cgatgaattg gatcgttggt ttgtccacga ttggcaacat ttcctttgcc atcgcctttg
    94801 ttgctggtaa aaatcttgtt cctaatcctg ctgctggaat aactgctttt tttactttca
    94861 tatacattcg ctccttcaaa aaattgttaa tgagaattca ttttcttttt tcccatcacg
    94921 taacatgatt tcttttgcgg ctgttttgat ttctttttgt tcatacagca cttcatagat
    94981 tgtttgagtg atgggcattt cgatttccat catttgggct agttccatcg ctgcttgagt
    95041 agtattcaca ccttcaacaa ccattcccat attggctagc acctcttcta gaggctgacc
    95101 ttgtcctaac aagttgcctg cgcgccagtt tctggaatga acacttgtgc aagtaacgac
    95161 tagatcacct actccgctta agccaataaa ggtcagcggg ttggcaccca ttgctacacc
    95221 taaacggctg atctcagcta atccgcgcgt catgattgcc gcttttgcat tatcgccaaa
    95281 ccctaagccg tgaatagcac cagctccaat ggcaataata tttttcaaag ctgctcccat
    95341 ctctacacca atcacatcag ggttggtata gattcgaaaa taatggttca tgaacagctc
    95401 ttgtacatat tttgctgctt ttacatttgt gcttgccgct gtgatcgtcg taatgtcatg
    95461 ctttgctact tcttccgcat ggcttggccc agaaagaaca gcaacagctt ttcttttttc
    95521 tgtcgggatt tcctctaaca agatttcaga gattctttta tgcgttccct gttctaatcc
    95581 cttacttgcg tggatgatca ctggcttcgt attcaatttg gcaactagtt cttttgcaac
    95641 agaacgtatc gctttcgtcg ggataacgaa tagtaccgca tctgcatctt ttactgcatc
    95701 ttccatatcg gtgaatgctc ggatggaatc gggtagatga tgatctggta aataacgttg
    95761 attggtgtgt tgggtgttga tttcttctac ttgtgaagca cgatgtcccc aaatccgaac
    95821 gtcatgtccg ttttcagcga ggacttgtgc taaagcagtc ccccaagagc ctggtcctaa
    95881 aaccgctact ctataattca ttttaccact cctgaaattt ttttcatttt taacgctctg
    95941 aaaatcaaat aatttgttga ttttttccta atgagcggtc ataatccggt aaacttcctt
    96001 tttttctacg ccaaataaac agaatcaatg tgccgacaaa taaaacagca gacaataatt
    96061 gagaaatgcg gatcacacct aaaaagtaaa ggctgtctgt gcgtaaccct tcgataaaga
    96121 aacgtccgaa actataccac attagataac ataaaaggac ttctcctttt ttcaaaagat
    96181 gtggtttctt ccgcaaaacc aaaagcagaa taaatccaat caaactccaa agtgattcat
    96241 aaagaaaggt tggttgtcga tagattcctt cgatatacat gttatcaatg atgaattgcg
    96301 gtaaatgcag actttctaag aaacttcgtg tcgtgtctgg accatacgct tcgtggttca
    96361 tgaaatttcc ccatcgtccg attgcctgcg ccaataatac gcttggtgca gcgatatcta
    96421 aaaaggtcca caaagaaata aaatgatatt tggtaaaaaa gtacagtgtg attgcacctg
    96481 caatcaatcc cccgtaaatc gctaatcctc ctgaacggat attgaatatc tggattggat
    96541 cagctatata ttggggaaga tcgaataaaa cataatacaa gcgggcacca ataatggaaa
    96601 tcggcaatcc ccacaacata aaatctgtca cgtcatctgc ttttaatcct acccgaacag
    96661 cttctctgct gctgagccac atggcaataa tgattcctga tacgataatc aatgcatacc
    96721 agtagatagg aattcctaca agctcaaaag caactcgatt gatttgtgct aacatattgt
    96781 cactccttgc tagtcattgc ctgagttttc ttcaatcaag cgacttaatc tttcttcaaa
    96841 tgttttcgtt gcgtcaaagc ccattgtacg tgcgcggaaa ttcattgcgg ctacttcaat
    96901 gatgattgca acgtttcgtc ctgttttgac agggattttt atttgtggaa tgcccacttc
    96961 cgcgatttca acggtcgtgt cttcagagcc cagacggtcg tatttcttat ctttcgccca
    97021 tgcttctaga taaacagcta actggacttg catagagcct cgtaccgcac tcgcaccgaa
    97081 aagattcatt acatctatga taccgatccc tcgaatctca atcagatgtt ccaggatttt
    97141 aggaggttct ccgattaccg tcagttcatc ttgctgatag acatctactc gatcgtctgc
    97201 gatcaatcga tgtccgcgct taatcagttc caacgccgtt tcacttttcc ctatcccact
    97261 gtccccttga attagtacac ctaatccgta gacatcgact aacacaccgt ggacacttgt
    97321 tcgaggggct aagcgtccat ctaaataact agataattca cctagcagcc gggacgttga
    97381 gataggcgaa cgcagcacag ctatcccatt ttcattggct gcttggatca tttcttccgg
    97441 agccggcaat cctcttgaaa taataaatgc gggcatatct tcactacata atcttctcat
    97501 aatgatcaaa cgctcttctg ggatcatccg ttccgcaaaa ctgatttctt tactgccaaa
    97561 tagctgtaaa cgattatggg aataataatt aaaataaccg gtcaactcta gtcctgggcg
    97621 tgagatgtcc ccagtcacga tgacgcggtc taaacttttc tcgtcgcctg tgacgatttc
    97681 caaagataat ttttttacta attggctaac ttttacaact tctgacattc atgctacctc
    97741 atttctatta gagtgttctc tatcatttta tcattgtcta gccaaaagta ctaccaatta
    97801 aaaaaaacgt ttttatttaa ttaccaatgt aatagaaaac gcattcttta ttctaaacaa
    97861 aaaa
//
LOCUS       DAIGTA010000002        96084 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.002, whole genome shotgun sequence.
ACCESSION   DAIGTA010000002 DAIGTA010000000
VERSION     DAIGTA010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 96084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.002"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            123..1394
                     /locus_tag="NOB43_000090"
     CDS             123..1394
                     /locus_tag="NOB43_000090"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI0981003.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            1391..2686
                     /gene="rho"
                     /locus_tag="NOB43_000091"
     CDS             1391..2686
                     /gene="rho"
                     /locus_tag="NOB43_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCI0981004.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            2785..3048
                     /locus_tag="NOB43_000092"
     CDS             2785..3048
                     /locus_tag="NOB43_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCI0981005.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            3493..3942
                     /locus_tag="NOB43_000093"
     CDS             3493..3942
                     /locus_tag="NOB43_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0981006.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            3999..5417
                     /locus_tag="NOB43_000094"
     CDS             3999..5417
                     /locus_tag="NOB43_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0981007.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            5417..6277
                     /locus_tag="NOB43_000095"
     CDS             5417..6277
                     /locus_tag="NOB43_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HCI0981008.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            6451..6561
                     /locus_tag="NOB43_000096"
                     /pseudo
     CDS             6451..6561
                     /locus_tag="NOB43_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
     gene            6845..7510
                     /locus_tag="NOB43_000097"
                     /pseudo
     CDS             6845..7510
                     /locus_tag="NOB43_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
     gene            7657..8022
                     /locus_tag="NOB43_000098"
     CDS             7657..8022
                     /locus_tag="NOB43_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HCI0981009.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(8170..9378)
                     /locus_tag="NOB43_000099"
     CDS             complement(8170..9378)
                     /locus_tag="NOB43_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0981010.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(9397..9675)
                     /locus_tag="NOB43_000100"
     CDS             complement(9397..9675)
                     /locus_tag="NOB43_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981011.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            9829..10524
                     /locus_tag="NOB43_000101"
     CDS             9829..10524
                     /locus_tag="NOB43_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0981012.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(10966..11763)
                     /locus_tag="NOB43_000102"
     CDS             complement(10966..11763)
                     /locus_tag="NOB43_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HCI0981013.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(11760..12944)
                     /locus_tag="NOB43_000103"
     CDS             complement(11760..12944)
                     /locus_tag="NOB43_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI0981014.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(12969..14216)
                     /locus_tag="NOB43_000104"
     CDS             complement(12969..14216)
                     /locus_tag="NOB43_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI0981015.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            14431..16176
                     /gene="dnaX"
                     /locus_tag="NOB43_000105"
     CDS             14431..16176
                     /gene="dnaX"
                     /locus_tag="NOB43_000105"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCI0981016.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            16196..16510
                     /locus_tag="NOB43_000106"
     CDS             16196..16510
                     /locus_tag="NOB43_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCI0981017.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            16535..17131
                     /gene="recR"
                     /locus_tag="NOB43_000107"
     CDS             16535..17131
                     /gene="recR"
                     /locus_tag="NOB43_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCI0981018.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            17195..17839
                     /locus_tag="NOB43_000108"
     CDS             17195..17839
                     /locus_tag="NOB43_000108"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCI0981019.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            17854..18183
                     /locus_tag="NOB43_000109"
     CDS             17854..18183
                     /locus_tag="NOB43_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HCI0981020.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            18197..19135
                     /gene="holB"
                     /locus_tag="NOB43_000110"
     CDS             18197..19135
                     /gene="holB"
                     /locus_tag="NOB43_000110"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCI0981021.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            19171..19995
                     /locus_tag="NOB43_000111"
     CDS             19171..19995
                     /locus_tag="NOB43_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HCI0981022.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            19988..20335
                     /locus_tag="NOB43_000112"
     CDS             19988..20335
                     /locus_tag="NOB43_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HCI0981023.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            20404..21276
                     /gene="rsmI"
                     /locus_tag="NOB43_000113"
     CDS             20404..21276
                     /gene="rsmI"
                     /locus_tag="NOB43_000113"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCI0981024.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            21385..22506
                     /gene="dinB"
                     /locus_tag="NOB43_000114"
     CDS             21385..22506
                     /gene="dinB"
                     /locus_tag="NOB43_000114"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCI0981025.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(22560..23162)
                     /gene="nrdG"
                     /locus_tag="NOB43_000115"
     CDS             complement(22560..23162)
                     /gene="nrdG"
                     /locus_tag="NOB43_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HCI0981026.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(23477..25666)
                     /gene="nrdD"
                     /locus_tag="NOB43_000116"
     CDS             complement(23477..25666)
                     /gene="nrdD"
                     /locus_tag="NOB43_000116"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCI0981027.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            25965..26759
                     /locus_tag="NOB43_000117"
     CDS             25965..26759
                     /locus_tag="NOB43_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981028.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            26749..28791
                     /locus_tag="NOB43_000118"
     CDS             26749..28791
                     /locus_tag="NOB43_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981029.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            29072..29221
                     /locus_tag="NOB43_000119"
     CDS             29072..29221
                     /locus_tag="NOB43_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HCI0981030.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            29232..30746
                     /gene="dltA"
                     /locus_tag="NOB43_000120"
     CDS             29232..30746
                     /gene="dltA"
                     /locus_tag="NOB43_000120"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HCI0981031.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            30743..31948
                     /gene="dltB"
                     /locus_tag="NOB43_000121"
     CDS             30743..31948
                     /gene="dltB"
                     /locus_tag="NOB43_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HCI0981032.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            31993..32226
                     /gene="dltC"
                     /locus_tag="NOB43_000122"
     CDS             31993..32226
                     /gene="dltC"
                     /locus_tag="NOB43_000122"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HCI0981033.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            32229..33497
                     /gene="dltD"
                     /locus_tag="NOB43_000123"
     CDS             32229..33497
                     /gene="dltD"
                     /locus_tag="NOB43_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HCI0981034.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            33638..34720
                     /locus_tag="NOB43_000124"
     CDS             33638..34720
                     /locus_tag="NOB43_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCI0981035.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            34720..35523
                     /locus_tag="NOB43_000125"
     CDS             34720..35523
                     /locus_tag="NOB43_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI0981036.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            35593..36333
                     /locus_tag="NOB43_000126"
     CDS             35593..36333
                     /locus_tag="NOB43_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0981037.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            36344..37348
                     /locus_tag="NOB43_000127"
     CDS             36344..37348
                     /locus_tag="NOB43_000127"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCI0981038.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(37393..39237)
                     /locus_tag="NOB43_000128"
     CDS             complement(37393..39237)
                     /locus_tag="NOB43_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981039.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            39449..39967
                     /locus_tag="NOB43_000129"
     CDS             39449..39967
                     /locus_tag="NOB43_000129"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0981040.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            40095..40778
                     /locus_tag="NOB43_000130"
     CDS             40095..40778
                     /locus_tag="NOB43_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HCI0981041.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            41087..41160
                     /locus_tag="NOB43_000131"
     tRNA            41087..41160
                     /locus_tag="NOB43_000131"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41121..41123,aa:Arg,seq:tct)
     gene            41319..41678
                     /locus_tag="NOB43_000132"
     CDS             41319..41678
                     /locus_tag="NOB43_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HCI0981042.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            41801..43432
                     /locus_tag="NOB43_000133"
     CDS             41801..43432
                     /locus_tag="NOB43_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HCI0981043.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(43494..44135)
                     /locus_tag="NOB43_000134"
     CDS             complement(43494..44135)
                     /locus_tag="NOB43_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI0981044.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    44321..44397
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            44417..44725
                     /gene="rplU"
                     /locus_tag="NOB43_000135"
     CDS             44417..44725
                     /gene="rplU"
                     /locus_tag="NOB43_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCI0981045.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            44752..45096
                     /locus_tag="NOB43_000136"
     CDS             44752..45096
                     /locus_tag="NOB43_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HCI0981046.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            45109..45402
                     /gene="rpmA"
                     /locus_tag="NOB43_000137"
     CDS             45109..45402
                     /gene="rpmA"
                     /locus_tag="NOB43_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCI0981047.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            45836..48643
                     /locus_tag="NOB43_000138"
     CDS             45836..48643
                     /locus_tag="NOB43_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0981048.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            48834..49325
                     /locus_tag="NOB43_000139"
     CDS             48834..49325
                     /locus_tag="NOB43_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0981049.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            49428..50417
                     /gene="manX"
                     /locus_tag="NOB43_000140"
     CDS             49428..50417
                     /gene="manX"
                     /locus_tag="NOB43_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCI0981050.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            50450..51253
                     /locus_tag="NOB43_000141"
     CDS             50450..51253
                     /locus_tag="NOB43_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HCI0981051.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            51274..52188
                     /locus_tag="NOB43_000142"
     CDS             51274..52188
                     /locus_tag="NOB43_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HCI0981052.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            52271..52645
                     /locus_tag="NOB43_000143"
     CDS             52271..52645
                     /locus_tag="NOB43_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HCI0981053.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            52784..53029
                     /locus_tag="NOB43_000144"
     CDS             52784..53029
                     /locus_tag="NOB43_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0981054.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            53201..54265
                     /locus_tag="NOB43_000145"
     CDS             53201..54265
                     /locus_tag="NOB43_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI0981055.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            54511..54936
                     /locus_tag="NOB43_000146"
     CDS             54511..54936
                     /locus_tag="NOB43_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0981056.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            54929..55378
                     /gene="nusB"
                     /locus_tag="NOB43_000147"
     CDS             54929..55378
                     /gene="nusB"
                     /locus_tag="NOB43_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCI0981057.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            55475..56329
                     /locus_tag="NOB43_000148"
     CDS             55475..56329
                     /locus_tag="NOB43_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HCI0981058.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            56330..57667
                     /locus_tag="NOB43_000149"
     CDS             56330..57667
                     /locus_tag="NOB43_000149"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCI0981059.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            57672..57896
                     /locus_tag="NOB43_000150"
     CDS             57672..57896
                     /locus_tag="NOB43_000150"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCI0981060.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            57898..58788
                     /locus_tag="NOB43_000151"
     CDS             57898..58788
                     /locus_tag="NOB43_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI0981061.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            58797..59615
                     /locus_tag="NOB43_000152"
     CDS             58797..59615
                     /locus_tag="NOB43_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HCI0981062.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVTVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            59722..60171
                     /locus_tag="NOB43_000153"
     CDS             59722..60171
                     /locus_tag="NOB43_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI0981063.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            60189..61871
                     /gene="recN"
                     /locus_tag="NOB43_000154"
     CDS             60189..61871
                     /gene="recN"
                     /locus_tag="NOB43_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCI0981064.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(61926..62042)
                     /locus_tag="NOB43_000155"
     CDS             complement(61926..62042)
                     /locus_tag="NOB43_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HCI0981065.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(62115..63071)
                     /locus_tag="NOB43_000156"
     CDS             complement(62115..63071)
                     /locus_tag="NOB43_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0981066.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            63242..63610
                     /locus_tag="NOB43_000157"
     CDS             63242..63610
                     /locus_tag="NOB43_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HCI0981067.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            63780..64211
                     /gene="mraZ"
                     /locus_tag="NOB43_000158"
     CDS             63780..64211
                     /gene="mraZ"
                     /locus_tag="NOB43_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCI0981068.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            64232..65191
                     /gene="rsmH"
                     /locus_tag="NOB43_000159"
     CDS             64232..65191
                     /gene="rsmH"
                     /locus_tag="NOB43_000159"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCI0981069.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            65196..65597
                     /gene="ftsL"
                     /locus_tag="NOB43_000160"
     CDS             65196..65597
                     /gene="ftsL"
                     /locus_tag="NOB43_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCI0981070.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            65598..67790
                     /locus_tag="NOB43_000161"
     CDS             65598..67790
                     /locus_tag="NOB43_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI0981071.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGIAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            67816..68778
                     /locus_tag="NOB43_000162"
     CDS             67816..68778
                     /locus_tag="NOB43_000162"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCI0981072.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            68792..70153
                     /locus_tag="NOB43_000163"
     CDS             68792..70153
                     /locus_tag="NOB43_000163"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCI0981073.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            70179..71267
                     /gene="murG"
                     /locus_tag="NOB43_000164"
     CDS             70179..71267
                     /gene="murG"
                     /locus_tag="NOB43_000164"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCI0981074.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            71282..72502
                     /locus_tag="NOB43_000165"
     CDS             71282..72502
                     /locus_tag="NOB43_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HCI0981075.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            72658..73983
                     /gene="ftsA"
                     /locus_tag="NOB43_000166"
     CDS             72658..73983
                     /gene="ftsA"
                     /locus_tag="NOB43_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCI0981076.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            74006..75247
                     /gene="ftsZ"
                     /locus_tag="NOB43_000167"
     CDS             74006..75247
                     /gene="ftsZ"
                     /locus_tag="NOB43_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCI0981077.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            75264..75941
                     /locus_tag="NOB43_000168"
     CDS             75264..75941
                     /locus_tag="NOB43_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCI0981078.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            75955..76554
                     /locus_tag="NOB43_000169"
     CDS             75955..76554
                     /locus_tag="NOB43_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HCI0981079.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            76569..76856
                     /locus_tag="NOB43_000170"
     CDS             76569..76856
                     /locus_tag="NOB43_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCI0981080.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            76905..77687
                     /locus_tag="NOB43_000171"
     CDS             76905..77687
                     /locus_tag="NOB43_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HCI0981081.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            77708..78415
                     /locus_tag="NOB43_000172"
     CDS             77708..78415
                     /locus_tag="NOB43_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HCI0981082.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            78677..81475
                     /gene="ileS"
                     /locus_tag="NOB43_000173"
     CDS             78677..81475
                     /gene="ileS"
                     /locus_tag="NOB43_000173"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCI0981083.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(81524..83050)
                     /locus_tag="NOB43_000174"
     CDS             complement(81524..83050)
                     /locus_tag="NOB43_000174"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCI0981084.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(83065..83712)
                     /locus_tag="NOB43_000175"
     CDS             complement(83065..83712)
                     /locus_tag="NOB43_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HCI0981085.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(83896..84225)
                     /locus_tag="NOB43_000176"
     CDS             complement(83896..84225)
                     /locus_tag="NOB43_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HCI0981086.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            84402..85130
                     /gene="sfsA"
                     /locus_tag="NOB43_000177"
     CDS             84402..85130
                     /gene="sfsA"
                     /locus_tag="NOB43_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCI0981087.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            85146..86159
                     /locus_tag="NOB43_000178"
     CDS             85146..86159
                     /locus_tag="NOB43_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0981088.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            86159..87436
                     /locus_tag="NOB43_000179"
     CDS             86159..87436
                     /locus_tag="NOB43_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0981089.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            87499..90201
                     /locus_tag="NOB43_000180"
     CDS             87499..90201
                     /locus_tag="NOB43_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0981090.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            90353..90670
                     /locus_tag="NOB43_000181"
     CDS             90353..90670
                     /locus_tag="NOB43_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0981091.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            90700..91020
                     /locus_tag="NOB43_000182"
     CDS             90700..91020
                     /locus_tag="NOB43_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0981092.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            91128..92588
                     /locus_tag="NOB43_000183"
     CDS             91128..92588
                     /locus_tag="NOB43_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0981093.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            92656..92877
                     /locus_tag="NOB43_000184"
     CDS             92656..92877
                     /locus_tag="NOB43_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981094.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            92908..93090
                     /locus_tag="NOB43_000185"
     CDS             92908..93090
                     /locus_tag="NOB43_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HCI0981095.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            93090..93503
                     /locus_tag="NOB43_000186"
     CDS             93090..93503
                     /locus_tag="NOB43_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HCI0981096.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            93626..94807
                     /locus_tag="NOB43_000187"
     CDS             93626..94807
                     /locus_tag="NOB43_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0981097.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(94878..95042)
                     /locus_tag="NOB43_000188"
     CDS             complement(94878..95042)
                     /locus_tag="NOB43_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981098.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            95196..95269
                     /locus_tag="NOB43_000189"
     tRNA            95196..95269
                     /locus_tag="NOB43_000189"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:95230..95232,aa:Arg,seq:cct)
     gene            complement(95338..>96084)
                     /locus_tag="NOB43_000190"
     CDS             complement(95338..>96084)
                     /locus_tag="NOB43_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0981099.1"
                     /translation="HIRASLKDAVEEGLIPFDPTRKAVIKGKDSLKPKEDKYLDYDQF
                     KSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDIDFEDQIITINKTWNYK
                     LNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEVKNPHNFVFFNLKNGLV
                     SSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNILSVSKRLGHSSLETTM
                     STYLHIVRELEDQDKEKINAVFDSLYKNDN"
BASE COUNT        31337 a        16512 c        20322 g        27913 t
ORIGIN      
        1 ttttgaagtc gctctccatt cttttttact taaaacggca gaccatgctc gtttcttttt
       61 tttatctatg ataaaataca agcatatcca tgaaaaaaga ttaataaaca aggtggaaac
      121 agatgaaaaa aatcgtaatc aaaggaaacc gacctttagc tggtgaagta acgatcagcg
      181 gtgcaaaaaa tagtgcagtc gcattgattc cagctgcaat cttagctgat tccccagtga
      241 tcttggaagg tgtgccggac atacaagatg ttcattcatt aattgaaatt ttagagatca
      301 tgggcgcaac tgtccatttt tccaacaaca tactagaaat cgatcctcga gaagtcgtat
      361 cgattccgat gccgcacgga aaaatcaata gtttgcgtgc ttcttattat tttatgggaa
      421 cactgcttgg taaatttggc gaagcggtag taggcctgcc aggtggctgt tatttaggcc
      481 ctagaccgat tgacctacac gtcaaaggat ttgaagctct aggtgctgaa gtgacaaatg
      541 aacatggtgc catgtattta cggacagaaa ataaaggatt gcgtggcaat cggattttca
      601 tggacgtggt ttcagtcgga gcaacgatca atgtgatgtt agctgctgta aaagcaaaag
      661 gacagacagt aattgaaaac gctgcacgag aaccggaaat catagatgtg gcaactttac
      721 tgaataatat gggggcaaaa gttcgaggag cgggtacaga tgtgatccgt atcgaaggag
      781 tcgaaacatt acatggctgt cggcatttca tgattcctga ccgcatcgaa gcaggaacct
      841 atctagcatt agcagctgca gtaggaaatg gtatcaaagt gaaaaatgtg atctttgaac
      901 atttggaaag ctttatagca aaattgcagg aaattggtgt ccatatgaaa atcagcgaag
      961 atgaaatcga agtttacccc tcgaaagaat taaaacccgc aaacatcatg acctatcctt
     1021 atccaggatt tgccacagat ctgcagcagc cacttactgc gttactattg atgactacag
     1081 gcacttcaga aatcatcgat acgatctatg cgaaacgtgt gaaccatgtg ccggaactag
     1141 cacgaatggg cgctgatatt accgtggaag gaaatatgat catcgtgaat ggtccaaata
     1201 aacttcacgg cacagaagtc gtggcttctg atcttcgggc aggtgcttgt ttagtgattg
     1261 ctggactatt ggcagaaggg acaacgacga tttacaatgt agattatatc ttacgcggtt
     1321 atgatcatat tatcgagaaa ctaacagcct taggggcatc aattgaaatg atagaggaag
     1381 tgggagctga atgagcgatt atttgacaat ggcagaacta gagaacaaaa cgttaaaaga
     1441 agtttatagt tatgccaaag aatttaaaat tccttattac agtaagatga ataaaaagga
     1501 attatctcta gctgtgattc gtgcacaagc agagaaacaa ggattttatt atatggaagg
     1561 aatattggat atcgttggtc aagatggtta cggtttttta cggccaatca attatggacc
     1621 aagtgcagaa gatatctata tttctgcctc acaaatcaga cgattcagtt tgagaaatgg
     1681 ggacaaagtg gcaggaaaag cccgtccacc taaagaatcg gaacgttatt atggtttgat
     1741 gcacgtggaa agcgttaatg gaaaagatcc ggaagaagca aaagaacgtc cgcattttcc
     1801 agccttaaca cctctttatc cgcaaagaca gcttcaactg gaaacaacac cgcaaagact
     1861 atctacccga atgatcgata tcttttctcc aatcggtttt ggtcagcgtg gattgatcgt
     1921 cgcaccgcca aaagcaggga aaacttctgt attaaaagaa atcgcaaatg gtatcaccga
     1981 aaactatccg gaagtagaat taatcgttct actgattgat gaacgaccgg aagaagtaac
     2041 ggatctagaa cgaagcgtga aaggcgacgt ggtatcttct acatttgatc tgcagccgca
     2101 aaaccatact cgagtttctg aattagtatt ggaacgcgca atgcgtttag tcgaagataa
     2161 acgagatgtc gttatcttga tggatagtat tactagactt gctcgggcct ataacttagt
     2221 cgttccacca agcggacgta cattgagtgg cgggattgac ccagccgcat tgtataaacc
     2281 taagaaattt ttcggggcag caagaaacat cgaagaaggt ggcagtttga cgattttagc
     2341 gaccgcttta gtcgatacag gaagccgtat ggatgacgtg atctatgaag aattcaaagg
     2401 aactggaaat ctagaattac aactttcacg tgaattatct gaacgtcgga tcttcccagc
     2461 catcgatatc aaaaaatcag gtacccgaaa agaagaatta ttgatgccaa gtgaagaatt
     2521 agaagaaatt tggaaacttc gaaaaaatat gactggagat tcattagaat atacggaaca
     2581 actgatccgc tttttgcgta aaacaaaaaa caatcagcaa tttttcaaag aatttcaaga
     2641 tgtctccttt ggtaaaaaaa atccgaccag aaatctgaaa agataattgc aaccttgact
     2701 gaaacatgtt aagatgttaa tgttgtaaat cgacaaatca actctggttc agcaaatgga
     2761 gcagggcaaa ggagcgaaaa aatcatgaaa gaaaacatcc atccagatta ccacccagta
     2821 gtattcatgg attcaacaac tggtttcaaa ttcttgtcag gttcaacaaa aacttcacaa
     2881 gaaacagttg aatgggaaga cggtaataca tacccagtca tccgtgtcga agtaacttct
     2941 gactcacatc cattctacac tggacgtcaa aaattcacac aagcagacgg acgtgtggac
     3001 cgtttcaaca aaaaatacgg tctcaaagac gcaaacgctg cggaataata aaaacgctga
     3061 taactcaacg tttagcagac tatctgatag ggatagtctg tttttttatg ttttttgcca
     3121 atttaaaact tcgtttgatg ctgaaaaagt cgtaggatca taatgcacaa aacaatgaaa
     3181 aactagtata tagttttaat tatccacttg ataaaaacac cttatattaa cgaaatgaag
     3241 aggggttatt tcgaagtaaa aaaccattta cctaaaatta gaagctaagc tttcctttca
     3301 aggaaggctt tttgttttgt tatagacttg cgattgtttg tgagctagat cgttcatttt
     3361 aatgacttat acacgcggat gatgggtctt tttcctctgt tcattcataa tattgaacgg
     3421 tacagctagc gatgctatac tgacctcagt tccaagaaaa cgttaacatt ttttgtgggg
     3481 gagaggtttt ttatgaggtt tgatcaattg atcgcagaag aactgattgt tttcgatcca
     3541 tcgatagatt caaaaggatc attatttgag cgaatagggg atgtgttgaa aaaaacaaat
     3601 aaggtaagaa atgttcaaaa agtcgttaag gcactattca aacgagagga ggagatctcc
     3661 acaggaatag aagatggatt tgggattccc catgcaaaaa gcaaatatgt gacaaaacca
     3721 gcactgtgtt tttttcatac agccaaatta acggactata gcgggataga tgaaatgcca
     3781 attgaatata tttttgccat cgtagttcct gaaaaatcag cagatatgca tctagagatt
     3841 ctcagcacac tctccagacg attgatgaat gcagatttta gaaagggaat aaaagaagcc
     3901 actacgccag cagatatcat cagacagatt agtcaagaat gaaaatagta gagtctttgt
     3961 ccgagtatcg atagtgaaga aaaaggagga aaataatcat gaaaatcgtt ggtgtaactg
     4021 cttgcccgac tggaattgct catacttata tgtcggcaga aaaattagaa gtaacagcaa
     4081 gaaatctaaa ccatcaagca aaattcgaaa cacaaggtgt aaaaacagaa aatcagttat
     4141 ctgaacaaga aatcaaagag gcagatgcaa tcattcttgc agtagataaa gaaatcgaat
     4201 tggaccgatt tgccgggaaa aaagtaaagc gtgtctctac aagccgagca atcaaagaac
     4261 cgcaagtagt aatagacgaa gcattgagag atattggcgt attcgttgtg tctaatgaaa
     4321 aagaaccagc tgcaaatgag aaaaagccga caatctataa tcatttcatg aatggtgtga
     4381 attacatgct tccatttgtg atcgcaggcg gaatcatcat cgcactgagt tttgcctttg
     4441 ggattacagc ggctgatccc aactcagcag actataatgt gttagcagct gcattttcaa
     4501 ggatcggagg agatacagcg tttgccatga tggttcctgc gttaggcgcg gggattgcta
     4561 catcgattgc tggaaaagca ggttttgccc caggaattgt tgccggatta ctggcctcta
     4621 caggtggttc aggttttctt ggcggaatga ttggtggcgt gctagcaggg tatatctgtg
     4681 attttctggc aaataaaatt agcgtaaaaa aagaattttc tgctatttat cagctgattg
     4741 tcgtcccctt tttatcgatc ttaattattg ggcttttgat ggtatttgtg attgaacaac
     4801 cgatcacatg ggtgttggat gctttgacaa attggctgaa tagcttggga aatacatccg
     4861 ggctattgtt cggattactt atcgggatca tgatggcagc tgatatgggt gggccgatca
     4921 ataaatcgac ttcgactttc tcgatcggtt tgatgtcagc tggagtaaat gcaccgattg
     4981 ctgcttgtat ggctgcagga atgacacctc ccctaggtat tgctttagcc actttattat
     5041 tcaaacataa atttaccaaa gaagaacgga cttcaggtca atcatgctgg attttaggcg
     5101 cttcgtatat tacagaaggt gctataccgt ttgcggtatc tgacccgatc cgcgtgatac
     5161 ctagtttgat gacaggttca gcagtcgctg cagggatttc catggcagta ggagttactt
     5221 caatggcacc tcatggaggg atttgggtga tgctaattcc aaatgttatg aacaatttac
     5281 ctatgtatgt cttggcaatt gcatcaggta cagtcactac agcctttatg cttggactat
     5341 tgaaaaaaac agtgaaagag aaaaaacaag acaagtggac gaaaaatgaa aatctaacaa
     5401 atgaggtgga agcgtaatgt tatatacaat gaaagagtta ttgaaagtgg ctaaagagaa
     5461 tcaatttgca gtaccagcct tcaatatttg cagctatgat atgatgaaag caatcatcga
     5521 agaagcagag agattagaag caccagtaat cttagaaatt catcctgatg aaatcgccta
     5581 tttaagtgat gagtttgttg cggcagtaag agcctatgct tatacaagta aactgccgat
     5641 cgttatccac ttggatcatg gcggtacgat agaagatgtc ttacgggcga ttcgaaacgg
     5701 ctattcttcc gtgatgatcg atgcgtcttt gaaatcattc gacgacaatg tacagattac
     5761 gaaaaaagtg gttgcgttag ctcatgcggt aaatgtctca gtggaggctg agcttggaac
     5821 gattgggaat aatggttctg ctgaaggagg tgctgaaaca atcatttata cagatcctga
     5881 tcaagcgaag atttttgtga aagaaacagg aatcgataca cttgctgtag caattggaac
     5941 agcgcatggc ttgtatccga aaaacagaac tccaaaatta aatatcgact tactgaaaga
     6001 attgaaccaa caaatcgatc ttccatttgt tttacatggc ggttcaggta atccggacgc
     6061 agaagtcagc gaagcagtaa aatacggagt tgccaaagtg aatttgagct cagatcttaa
     6121 aagcgtcttt ttcaatgctt tgagagaaat attgagtgaa aatccatcga tgtacgagcc
     6181 gaatgcaatt tatccagcag ctaataaaaa ggtacaagaa gtggtcaaac ataaaatgga
     6241 aattttgaac acagtaggca aggctagttt atactaaaaa taaaaatgtg tggtcaagag
     6301 ggtatgacaa tagtcttgtc ataccctctt aaccacacac gatgttcaga agtagttttt
     6361 tcgaaaaatt tcttcttatt tctcgaagcc aatcacttct gtcacaacct cttttttcct
     6421 gttactatat aaagtaaatg gggtgatttt atgttgaatg aagtggagaa tagacagcag
     6481 gagattgtga attatctaaa aaacaaccaa tttgcaagag tcaccgattt gatcgagtta
     6541 gtaaattata gcgaagccac gagtgaacta ctcaccactt agctaaacct gacggttctt
     6601 aacgcttgaa gtgggagctt cttgggaata gagcatactt gatagcgtat ttctttacta
     6661 acagcggtgt ctcttattta ccaagctatc cccgtagttc ctacggttct tgatgattgg
     6721 atctaagcca atcccataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac
     6781 ggtaaccctc ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc
     6841 taattctgtt aaacgtgacc ttgtttttct ggaaaaaagt ggattgatcc gtagagttcg
     6901 cggtggcgcc atgcttattg acaatcgaaa aattgacgtg ccttacctga tgaagatcac
     6961 caaattagaa gaagaaacag aaaaacgtaa gattgcagat acagcttctt ctttgattcg
     7021 agatgatatg gtcttattct tggattccag tacaacctct ttacacttag tcagaaacct
     7081 agcaagattt gatggtttgc agatcattac gaatggcatc gtcacagctg ctatgttgag
     7141 tgaatataca acggcaaaag tatctgtatt gggaggggca attgttccga aacgagcaac
     7201 aatcaacggt tcaaaagcct ataacgatgc attgtcatat tatgcggatt tagcgataat
     7261 gagttgtcgc gggctagatt tcagccaagg agtaacagaa actcatgaag gagaggcaat
     7321 ggtcaaaaaa gcttttagaa aacaatcaga ccggcttgcc gttttagtta cacagcaaaa
     7381 aattgcacat aaattcatgc atcaagccat tgcttttcat gaaatcgatt atctggtgac
     7441 aagtaaagaa ctgacaaaag aacagtatgc gaaagtaaag gaacaccata tcgaatgtct
     7501 gtacggataa attattacgt gaatgttcta agtggcttcc tcatttttag ataggacctt
     7561 atctttgctc gcttctctca gccgatggta taataatgaa aaggttatct tgttagataa
     7621 tcttactttt ttatccagga gaaaggagtg cagaaaatga aacatgtgaa ggcgttggta
     7681 gtgaaggcaa tcatgatctg ggcgattctg tgggtcgtgc tgacaggttt atacggtgtt
     7741 agctttatgg attcaacgat tgttggggta attattgtag tcatgatcta tgtgctaggg
     7801 gatctgttga tcttacgtaa agtagggaac atcgcagcga cgatcgcaga tgctggttca
     7861 gctgcagtta tcttgtggct ctatctatat tttatgaatg atacagtcga tatttggatg
     7921 aaagtattga ttcctgctct attgatcggt gtggcagaat ggttcttcca caagtggttg
     7981 ctaagtcaag gcatcgtacc agatgaacgg aaaatggaat aaatcaacag ttaaactatt
     8041 cttatcgata aatgaaagct ttaaaaataa atagatgttt aattaagaat aatcataaac
     8101 tatttttact caaaaaaccg ctcagattat tttcagatct gaacggtttt ttttatctat
     8161 tcatcaagat caaatttcat ttttcaatga ttcaatcaat tcgccctctg cttcatgact
     8221 atgttttcgg ccattaacaa gatagagtgc tgtacatatc aatggaatga ctccggcaat
     8281 cacatacaat cctctaaatg aagtaagaga ttttagcatc cccatcaaat aaggaccaac
     8341 gcctaagcct aggtctaaac caataaagta ggtagataaa gcaatactga ttcgatgttc
     8401 gcggacgatt tttaaacaaa cagcctgtcc atttgacata aacgtaccat aacctaggcc
     8461 gactaatgct ccagagataa gcaatgtcac actattcgtc gttacactca gtaaaaataa
     8521 tcctgctgtt aagaataaat agctaggata catcacgtat tgttctcctt tgacatcgaa
     8581 aatccttcca gtcaatggac gtgtaaatgt gatgaccaaa gcatatacga cgaagaaaaa
     8641 tgacccagca gcaactaagt ggattacttt tgtataagaa gataaaaatg ataaaacact
     8701 tgaataagaa agacccatca aaaaggcaat tcctgtaatg aaaagtgctt tcttttcaat
     8761 aaaactattg atattccatg agcgaagaga tattttttgt tcttcagata atggaatatt
     8821 ttttacagga aagacaaggc aggcaatcgt aacaaagaag accagtacaa ttgaaaacca
     8881 gataatgaaa cgaaaatcag tcatattcag caaaatcatt cctaaaaatg gcccaacagc
     8941 ggcagctaaa ctagtactta atccataata attgatgcct tccccttttt tagatgcagg
     9001 gatatatgca gtaacgatag catttgtagc tgtagaaact gtaccgtagc cgaatccatt
     9061 caagaatcga actaaataca atgccccgat agttggcgta taaagatatg ctaatgttga
     9121 aaggagatag aagatcgcgc cgcctcttaa ggtaaacttc cgaccaaata gttctaactg
     9181 tttccccatg aataagcgtg ccagcaatgt tccgatgata tagatcccag aagcaaaacc
     9241 tgcttggctc aagctggcgt gtaaggtgtc ttgcgcaatg actgccatga tgaccatcaa
     9301 cagataataa atcaggtaga caataaaatt gatcaatgtg attccaataa aatatttatt
     9361 aaataatttc ttttccatgt atgttataca ttccccttaa gctgaatatg cttttaattt
     9421 ttgtatttga acttctacat cgtgataatt ggatggatag cgatcaacaa gttggcgaat
     9481 aaataaatct cttgtagaca taaacagatt taaaaattct tcgcattcgt ttgttggatt
     9541 ctcatccact gctttgatca attcgatcga gttttgatac gcatcattta aaaagactaa
     9601 agaagctttc atatcaaatc ttgtttgata tgctgtttct aatcgattaa tgattgtgtt
     9661 catccagtaa ttcatgtttt ttccctctat tcttaaaaaa ttttacttct gcagtataac
     9721 gaataaaaaa aaggaaaaaa atcgcataag tgatggaaaa aggtacttaa caaatgttaa
     9781 tatcattagt aaaatacctt tggactttaa aaagttttaa agtactgtat gatcttttta
     9841 gatgaaagtt tggatggggg agcatcattg gatagtagag tcttaaagga atatttggat
     9901 aaaaatgatt ttccgattat acgcaaagga tatcataaat atttgacatt cgaagggatg
     9961 gaagattccc atacgtatat cttgaaagag ggaacggtaa aagcaagtgt tatttcaaat
    10021 gatgggagag aatttaacct tcgctatatc aaagatcttg aaatcgtctc tcttttaaaa
    10081 gacgaatatt cacaattcat cgattcgccg tataatattc gagttgaatc agaatatgca
    10141 gagttttatc gaatcaatcg tgtgcgcttt tggcaaaata tcaaccaaga cccaaagcta
    10201 caacactatg taaaagagta ttaccgctat cgtctgcttt attcgatgaa aaaaatgcag
    10261 caaatgctat taaacggaaa gctgggagct gtttgtacgc aactttacga attatatgat
    10321 ttattcggtg tgcggacaga agaagggatg ctgatcgatt tttcgatcac gaatgaagaa
    10381 atcgccaaat tttgtggcat ctcaactgct agcagtgtaa acagaatttt aaaacaactg
    10441 aaaaaagatg gtattatcac cgttaaagac catcatatcg ttattttgaa tatggacttg
    10501 ttagaagaca atattatctt ttgatgaaca aagaggttgt gaaatcagcg ttttgacctg
    10561 agtattagag aaacaaacgg aaaaatagtt cctcatattt tgccgttttt tgagctaata
    10621 ccgagggtca gctgattgaa caccgtttac caagaggttg tgagcctgcc gtttaactct
    10681 gagtcacaag gaacaatttc aaaaaacagc ttttcatgtt tgatgaatat tgtgacttgt
    10741 gaccgaggag ttggtaggag aacaccgttt accaagaggt tgtgaaaaag ctgttctgca
    10801 tcaagtaata agaagagcca agtaaaaaca gtctcttatg tttttaactt ggctggactt
    10861 atcaccgtag atgtaagctt ttgaacgccg tttatttgca acaaaagggg ctgtgacacg
    10921 atttttgtca cagccctttt tttgcgaaca ttcatttagc aatttttaga aacttctgcc
    10981 gccaccgcca aaagtcccgc caccgctaga atgggtagta cttccgccac cgccgcttcc
    11041 aggaggtggg cttttgggga ttcttcttgt cgtgacaaaa gaatttgtca gacgatcggt
    11101 tttttcagtt aatttgatac tggatttttc tcggaatgga tatttgtaga tgcctgattt
    11161 caattgataa cgcgaaacag tcacaaaata aaagacaaga ctaaggataa gagccaaaac
    11221 aacagcaatg atgatttcta ctgtcgtcaa aaccttatag cgtgtaattt tgccagtttc
    11281 ttcgtctaca cgataatgtc ctcctggaac tccgtcttcc acatatgttg ctgatttaga
    11341 caggtaagct tttgcagcat tgtaataggc agcatttgtc atctgatcat aaacatcatc
    11401 taagatcgaa tcgattctgc tatcagtcaa ataatcgatc atattaccag aagtcgaaat
    11461 gtagatttca cgctgtccca tatctaatag caatactgag ccattttgat catttccgac
    11521 tgcgtctctt aagtaattat cagcaaagtc tcttggttct tctgaattag atgtagtcgt
    11581 tacgatcaag actcgtcctt tgattttttc attcagcttt tctgcctgtt gttccaaaga
    11641 ttggatttga tctgttgtga ataacccagc ctcatcattt accgtagctg tatctgcatg
    11701 agtagccacc ggccagccaa cacttactag caaaagaaag aataaaaaaa attttttcat
    11761 catatcaagt aacctccgat cagaaagagg atcgctagcc cagcgaaaat cccaagagcg
    11821 gtcagtccca attttttctg gctgatcggc aggacaccgc tgacctttcc tgtttgtcca
    11881 ttcattgcgt agtagtagac ttttttactt gagtcattgc ttcgataagt aacaagccat
    11941 accggcagta atacgtaatt atttacttcg tttgtgattg aagcagaagt tcgcacaccg
    12001 gtcaatgttg tatatccatt tgcggtatct tttaacagct tctctgaata gtcttttaat
    12061 tcagattgaa tctgtgattt gattgcctca tattcgatat ctcttttttc tgcttggaac
    12121 ccggctaaat actggctttt aaaatcaatt gctttatcta acgggaaagg ttgcacgcct
    12181 tcgaccatct tttgttgcgt attttttgat aaggcatttt ttactagttc tttaaaagaa
    12241 agcttgcctg ctcttgaaac agcaaattgc ttcgtttctg tgtattcgat gtcacctatc
    12301 cgccatatgc ggataactgt accattcgcc tgcatggcac catctacttc agcatctgta
    12361 gcccaataag ggaaatacac acctgtcaac ttatcgattt gatccttatt gaaaaaagct
    12421 ttgggaacaa accatttttt cttggtccaa gcgagaaatc tgttgattgc ttcttctttc
    12481 tcgacagcaa aaggaagtac tttatttggc aagaattctc cgcttaaacg tcccgatagt
    12541 acgacgggat tatggcagta gtaacaataa gtcgcagcag ttgtcgcatc agtcacgatc
    12601 tctgcaccac agttgggaca aagaaaaaga tctatcgctg cggtattatc tgcagattcg
    12661 tccgctgtat ctgaaaaacc gcctgcctcg tcaaccgctt tgcgctcggc ttcattcata
    12721 tcggcaagct gttcttgggc tgtaaaagta aaatcttcgg taggtgaagg ttcttctttg
    12781 ctttcttcgc cagccatacg cgcttctttt tgcttttgct catattggct gacttcttct
    12841 tctgtataga tattcaggca gtattcgcaa tgaaattttt ggtctttggg atcaaaagtc
    12901 aacggaccgc cgcaattagg acatttatgt gtaagaacat ccatcagctg cacacctttc
    12961 taaataaatt aattaacggg gattccttta aacggtttac cacagtttgg acagaattta
    13021 gggatgccgt tggaaagatc cacgatctca ttgcattcac tgcatcgcat ttgtagctta
    13081 ggctgaacgt tttctacagg tttggcagct ccgcagttgg aacagaattt tccggaattt
    13141 tctgtcccgc aaactggaca tgtccaagta tccgcatttc cttgtgcagt ttgttgattt
    13201 tgtttttctg cttgttgttt gatttgttct tggttatttt gagctgcttg agaaagataa
    13261 gaaccatttg cattcattcc catacctaca cccataaagc cggtcattgc tcctgcttca
    13321 ttttttccgg ctgcttccat accacgtgca atggaacctt gcacgtatcc ttcacgtacg
    13381 ctaggatcac ctagcatcgc cccttcgtta cgcatattga tcagtttcac agaatcatcg
    13441 gtgtaagaaa tgctggctac agccacagaa acaatctcca tcccacgtaa ttcacgccaa
    13501 gaatcatcca atgcagtatc catgtatttg cttaattcca aactcttaga tggtacataa
    13561 gaaatccgtt gaccatctgc agacatctga ttgattgctg attgtagcgc tgttaggaat
    13621 tcagctaaat actgctcatt gatatcattg atttccactt gtgttttgtt tttagggatt
    13681 gcgtttgtat aaaataaaat cgggtcaacg acatgaatag aataagtgcc atgtgcccgt
    13741 aagaataatt ctgcgttata gaaattgtca aagtagttca acggcgcgct tgtaccgaat
    13801 ttgattccct ttatttcttg gagattgata taaaaaactt gttgtttctg cggtgtgacg
    13861 ccgccaaatt tgaatcggtc aaaagtttca gcaattgctt ctttcagtgt tccattgaac
    13921 atggaaggag ctgcgtcatt tttaatggtg taataacctt cctcagcggt ataatcgatg
    13981 atttttccac catcgaccaa aagcatcatc atgtttggat agacatggac gactgttccg
    14041 tctgttaaaa catcttctgt tcctttacga ttggagccac gtttgtcatc tttgcggact
    14101 ttgacacctt ttgtcatgac cgttgtatca ctcatattgt ctggttcgat gacttctagc
    14161 cattgatctg ccagaccgcc gccaaccata cttgttgctg ctttgataag acccataaaa
    14221 aattcctcct ctgattcagc tagtgccaaa caattattgt ttatttatta taccatagga
    14281 agatgtgaaa cttctcggac tagagacgga attgaaatgg aaaattgcgt attgtttaaa
    14341 tacctgaaaa agccgagaag gatagtagtt tttttaccta atatcacgta taataagaga
    14401 tagtgaattt tttaaaaaag ggggatcctt atggcatatc aagcacttta tcgagtctgg
    14461 cgttcgcagc gtttcgaaga catcgttgga caaaaagctg tgacacagac actaaaaaat
    14521 gctattgttt cccacaaaac ctcacatgcc tacttgttta caggacccag aggaaccgga
    14581 aagacgagtg cagcaaagat tttcgcaaaa gcaatcaact gtccgaacag taaagacggt
    14641 gagccatgca acgaatgcga aatgtgtcga tcaattactg ctggtacgca agaagatgtg
    14701 atcgaaatcg atgctgccag caataacgga gtcgaagaaa tccgatttat ccgtgatcgg
    14761 gcaaattatg cgcctacaaa ggcagcgtac aaagtgtaca ttattgatga ggtacatatg
    14821 ctttcaacag gagctttcaa tgccttgttg aaaacattgg aagagccaaa agaaagtgtc
    14881 atattcatct tagcaacgac cgaacctcac aaaataccag ctacgatcat ttcacggact
    14941 cagcgatttg attttaaacg gatcaatacg gcagatattg tcgaacatct tgaatttatc
    15001 ttgaaagaat cgactatcag ctatgaacca gctgcattga atgtgattgc ccgttctgca
    15061 gaaggcggga tgcgggatgc attgagtatt cttgatcagg caatctcgtt tagtgaagga
    15121 acaattactt tagatgatgc catgcaagtg acaggtagct taactgacga aatgatggac
    15181 agttacttga gtgcttgcgt gaaaaaagaa gtaccagaag cattggaaac attgaaccaa
    15241 attctcgcag ccggcaaaga atcacgtcgc tttctagagg atatgttaca atactgccgt
    15301 gacttgctga tgtatcagca agcacctaac ctagttgagg aacaatcgag tacgatcaga
    15361 agtacattta cagaattggc acaaactgtt tcagcggatc agctgttttc aatgataaag
    15421 attttgagcg atactcaaaa tgaaattcgt tttaccaata gtgccgctat ttatttggaa
    15481 gtcgctacag tcaaacttgc acagctaccg tctgcttctg ttccttcagc agatgtagca
    15541 tttgcagatg atcagatagt aaaacagcta caacaagaga ttaaggaact aagaaacgaa
    15601 atcaaggaac tacgcagtaa tacaggaatt gagaatacaa aagtacagcc ggtacagcaa
    15661 acaaatcata aaaaacagac aagtacctat cgtgtaccga cggaacgagt atataaagtt
    15721 ctgcgggaag cgacaagaca gcatctgaac caagtaaaag aagtatggga agacttgctg
    15781 atgagtctat ctgtcactca gcgagcaatg cttaaagcaa gcgaaccagt tgcagctgga
    15841 cctacaggac tagtgattgc gtttgattat gagattgttt gtcaaagagc agcaaatgac
    15901 gaagaattgc agctttcggt acacaacaac ttaagccgaa tgatcaaaga ttatgcgcct
    15961 gatcctgttt atattacaag agaaagctgg ccagaacttc gaagaaatta tttgacgcag
    16021 gcacaagaag agggaacaga aaactctttt gcttctgaag actcagaagg agaaatcgag
    16081 ttgcttcctc aagaacaaga agtaccagaa gaaacacttg tagtaaaagc agaggaactg
    16141 tttggctccg aagctgttac agtggtagat gattaataaa aaggagtaga taattatgat
    16201 gcgtggaatg ggcaatatgc aaggcatgat gaaacaagta caaaaaatgc aaaaagaaat
    16261 ggcagaagca caagagctgc taaataaaac agagtttaca ggtaaagcca ccaatgaatt
    16321 ggtcaaagcg gtttttacag gcgatcgtcg catgaaagat atccaaatca atgaagaagt
    16381 cgttgatcct gatgatatcg agatgcttca ggatcttgtc gtaatggcag tcaatgatgc
    16441 gatcgcacaa attgatgtgg aaactgagaa aaaattaggg aaatacgcaa aaggtttgcc
    16501 aggattttag ttttaaactg aaggagtaat gaatatgcaa tatccagaac caattgcgaa
    16561 actgatcgac agctacatga aacttccagg aatcggtcag aaaacagcga caagactcgc
    16621 cttttatacg atcgatatga aagatgaagt agtaaatgaa tttgctaaat ctttgttaag
    16681 tgtaaaacgc gatttgcatt tttgtagtat ctgcggaaac atcacagaag aagatccctg
    16741 cgaaatatgt agaaatcctt cacgtgatcg aagcgttatc ctagtggtcg aagagccgaa
    16801 agatgtaatg gcaatggaaa aaatgcgaga atatcacgga ctttatcatg ttctccatgg
    16861 tgtgttatca ccgatggaag ggacaggtcc agaagacatc aatatttctt ctctgttgca
    16921 gcggctgcat gatgcagatg taaaagaagt gattatcgca acaaatgcaa caacagaggg
    16981 agaagcaaca gctatgtatc tctcacgtct gatcaaaccc gcaggtatca aagtgactcg
    17041 tctagcacat ggtctgtctg taggctctga tatcgagtat gcagatgaag ttactttatt
    17101 gaaagctgtc gaaggaagac gtgagttata aatttctaat taagtgtttt ttcagataca
    17161 atataaaagc agcacaagag atgggggcaa caatgtgaac ggactattta ttacaatcga
    17221 ggggcctgat ggtgcaggaa aaaccagcat cttgaatgaa ctttaccctc ttttgaaaga
    17281 agtagcaaaa acagaaatca ttcaaacaag agaaccagga ggcattccga ttgctgaaga
    17341 gatccgagca gtgatccttg atccaaaaaa tgatcggatg gatgaacgta cggaagcact
    17401 gctttatgca gcagcaagaa gacaacatct agtcgaaaag gttctgcctg ctctggcaaa
    17461 agggaaaatc gttttatgcg atagatttgt cgacagttct cttgcttatc aaggtgcagg
    17521 ccgacgcatc ggcgttaccg agattgctcg gttgaatgag tttgctacag aaggtactac
    17581 gccggatttt accctttatc ttgacgtaga ttcagacacc ggattaagaa gaatcaagaa
    17641 aaacagacaa aatcaaatcg accgtttaga ttcggaaggt ttggaattcc accagcgtgt
    17701 acgtcatgct tacttaaagc tggcagaaga gaatccggaa agaatccaca aagttgatgc
    17761 aagaaaaagc tttgaagaag tgctgcaaac aagttatcat acaattattg aacagtatcc
    17821 gcaatttttt gaaaactagg aaggtgaacg tttatgaaaa ttattttagc gattatccaa
    17881 gacaaagaca gcaaccgttt atcaaatgaa ttgattgatg caaatatccg tgccacaaaa
    17941 ctatcatcga caggcggctt ccttaaggct ggaaacagta cgtttatcgt gggtattgaa
    18001 gatgaccgtg tagaagaagc attggaaatc atcaaaaaaa cgtgtgaatc aagaaagcaa
    18061 tttgtatcta cacctgttac actggatatt tcgatggatg ggggcgtccc ttatccagta
    18121 gaagtagaag taggcggtgc cacagtcttc gtcttacctg ttgaaggatt ccatcaattt
    18181 taggaggagc tgagctatga atcaagaaat aaacttggct caaatgcaac cgatcgtgta
    18241 tcagcagctt caacggagtt ttgagcatgg gcgtatcgct catgcttatc tttttgaagg
    18301 ggagaaagga acaggaaaac atgaagtagg tatatggctt gcacagcacc tgttctgtac
    18361 ccaaatgaaa gacaatctgc cttgtggaaa atgcaacaat tgtcagcgga tcgaaaagaa
    18421 agaacatcca gatgttttgg ttattgaacc ggaaggacaa accatcaaag tcgatcagat
    18481 cagacgtttg cagacggaat tcagtcgcag cggttacgaa tcaagaaaaa aagttttttt
    18541 gatcaaagaa gctgaaaaaa tgaatagcag tgcggcaaac agtttgttga aattcttgga
    18601 agagccccct ggagattttt tagcggtgtt agaaacagat gcagtaggaa gaattctccc
    18661 tactattcaa tctcgttgtc aagttctgca ttttcaagaa ctttcgaaag aagcactgat
    18721 ccatcgattg caagaagagc agattccatt ggaaaaagca aaacttttgg ctttcttaac
    18781 aaacagttta ggaaaagcag ttgaaatctc tcaagatgaa tggtttaatg atgctaagga
    18841 cttgatttat caatggttcg tttacttgca aaagcaagat actcaagcct ttatctatgt
    18901 ccaaaaaaaa ttggtaaaat catttaaaga aaaaacacaa cagtttacag gattatctgt
    18961 cttgatgttt tattatcagg aagcacagcg tcaagcagta gcaaacggcg aatatggcaa
    19021 agtgaaacag ataaaccaga taattgaacg gatattgatc gcagagcaga aactacgcag
    19081 caatgtcagt tttcaggctg ttgcggaaca gttcgttttg catacgattt tttagcttgc
    19141 cgcaaaggat gatgatcaag gaggatggaa atggtagaag tagtaggtgt ccgatataga
    19201 gatgcaggtc atatctatta ttttgcacca ggagactctg aatatgttta tagtgacaag
    19261 gtattagtcg aatctcagca atccttacat attgctactg ttgtccttcc taaaaaagag
    19321 attgatccca atgaccttcc tgaagctatc cgtccgatct tgcataaagc gtcacaagct
    19381 gaattagaaa aagacaaaaa aaacaaaaaa gatgcttatg atgcattgaa aatcgcaaaa
    19441 gaaaaagtgc agttgcgtga gttggaaatg aaaatggtca aagccgaata cacatttgat
    19501 cgaaataaat tgattttttc tttcacagcg gacgggcgaa ttgactttag agaattggta
    19561 aaagatctgg ccgctgtatt tcgtactcgt attgagcttc gacaaattgg tgtccgcgat
    19621 gaagcaaaga taataggcgg aattggtcca tgtgggcgtc cattatgctg ttcttctttt
    19681 ttaggcgatt tcgtgcctgt atcaatcaaa atggcaaaag atcaaagttt atctttgaat
    19741 ccaacaaaaa tttccggttt atgcggacgc ttgatgtgct gtctgcaata tgagagcgaa
    19801 gaatacgaga cagcgaaaaa agaactccct gactttggaa aagtaattgc tacacctgat
    19861 ggtaaaggga aagtcgtagg gttgaatctg cttagccgta tcgttagtat tcggctgact
    19921 ggacgggaaa atcctgtcga atatgaatgg gatgaattga aagaatttat ccaagtaggt
    19981 gagatgaatg gataagagat cattatacga cggattgaat caattagaat cagagttgag
    20041 aaatacatta acagaacttg ttgaaatgaa gcatgctttg catgagatcg tagaaaaaaa
    20101 tacaactttg gagatggaaa atcaacgtct gcgggaacac ctgcgggaat tgaaccaagt
    20161 tgcacaagct ccagctgaaa atgtgaagca ggaactttct aagtctcgta tgaatcttga
    20221 aaaaatttat gaagaaggat tccatgtctg ctacgattta tatggatcaa gaagggacaa
    20281 tgacgagcct tgtgcgtttt gtctagaagt gatctatcgc gaaagcggtc gatgaccaat
    20341 aacaagagga gactggagcg gagaaatact gctccagtct ttttattaag gagattgtga
    20401 cagatgtata atcaaaaaag tttcaaggga aatccggtat atggggattt atatcttgta
    20461 ccgacgccaa ttggaaattt agaagatatg agctacagaa gtgttcgtat gctgcaagaa
    20521 tccgatctta tcgcaagtga ggatacgcgt aatacacaaa agttattgaa tcattttgaa
    20581 atccatacac cccaaaaaag tttacatgaa cataattata aagaacgtgt ccctcaattg
    20641 attgctttgt taaaagaagg aaaaacgatt gctcaagtca gtgacgcagg aatgccttcc
    20701 atcagcgatc ctggacatga gctagtttta gcctgcataa aagaagggat ttctgtgatc
    20761 tctatcccag gacctacagc tgggatgacg gctttgattg cttcagggct agtgcctcaa
    20821 ccatttttat tttatggctt ccttccacgt aagaaaaaag aacagaaaga aacattgaaa
    20881 aagctaaaag aacagacagt tacgctgatt ttttatgagt caccttatcg gatcactgct
    20941 acattgacga atttcttaga aatttttgga aatcgccaag tcgttttgtg tcgggaattg
    21001 acaaaggtcc atgaagaata ccttagagga agtacggaag agctactcgc ttatatcgaa
    21061 gaacatccag taaagggtga atgttgtctg cttgtagaag ggaatttgtt cgaaatgcca
    21121 gtgacggaag ttgatgaaga gttgggaacg ttaaaggaac aagtagaagc aaagatcgct
    21181 tcaggcgaaa aaccaaatgc tgctatcaaa gcagtagcgc tgaaaaatgg gctgaaaaaa
    21241 caagaagtct accgtcagta ccatgaatta gactgagata gtataagttg tctataatga
    21301 aagactaatg aggaaatcag ctactaactt ttcaaatctc ttgaacgcga acgaatgttc
    21361 ttgtataatg aataagaggt gaggatgatg gagctgcaat ttcctttaca taatgataca
    21421 tcaagaaaaa tcattcatat tgatatggat gcttttttcg cttcggttga agaacgagat
    21481 catcctgagt ttcgcggaca tccattagta attgccagac accccagtga cactggtggg
    21541 cgtggagtag tgactacagc aaattatgaa gcaagaaaat tcggaattca ttcagcaatg
    21601 agtgcacaaa aagcgtatga gctttgtccg caagccatct ttaagcctgg cgaccatcat
    21661 aaatacagcg atatttccaa acaagtacgg gaagtattct atcgttatac agatattgtg
    21721 gaaccagtta gtatcgatga agcgtatctt gatgtgaccg aaaataaaat caattgcaag
    21781 tcagccatca aaatcgcccg aatgatccaa gcagatattt gggagagtgt ccagctaaca
    21841 tgttctgcgg gagtaagtta caataagttt ttggccaaat tagcatcaga ctatcaaaaa
    21901 cctagaggaa tcacggtagt tgcccctcaa gacgctgtgc catttttaaa agctttgcca
    21961 attgaaaaat ttcatggggt agggaagaaa actgtaccta gaatgcatga gctagggatt
    22021 tatacaggaa aagacctata tgaatgcaca gaaatgatgt tgattcgaaa ttttggaaaa
    22081 atgggctatt ctctttatcg taaagtcaga ggaatccatg attctccagt aaacgttaca
    22141 agagagcgaa aatctgtggg aaaagagcat acttatgggc agccgttgca aacggaagaa
    22201 gcagtgctga ctcagttgcg ccaactagct gaaaaagtag aagaagcact gagaagagtc
    22261 caaaaacatg ggaaaacagt agttttgaag gtcaggtaca cggactattc tactgtgacc
    22321 aaaagagtga cattgccaga atatatctat aaaaaagaag cactctttta tcaagcaagc
    22381 cttatatggg aggaaatctt gggagtagaa aaaggaatcc gattgttagg gattactttg
    22441 acgaatctgg acccgatgac ttatgaaaac atcgtccttc cattatggga aaatcaagaa
    22501 atataaaaac agctttgaga gttgaaaccg gaaatccgtt ttctctccca aagctgtttt
    22561 tatatcaagt cttgcttttt gatttgttca taggtttctg ttgcatccgt acatttttcc
    22621 caaatcacaa cttgattgga ttctaaagat ttttggacgt caatgatccg ctggttgcta
    22681 cttccgcgaa attgtagttt taggtcacgt ttgcttaatt caaagcgtcc gtcaacaagg
    22741 atatcgattt gcgaaaggag ttctaattta tcttctgaat cttgtagcaa ttcatcaaag
    22801 gtatagcctg tccatgacca gatatctttt gtcgtaccga actcttttcg gatacgtcgt
    22861 acgacttgca gacaaacatc tgtattcaaa aaaggttcgc caccaagtaa agttaatcct
    22921 tgcacgtaat cgttgcgcaa gtcagcgatg atttgttctt ctaattcagg tgtgaatggt
    22981 ttgccatatc ggaaattttg tgcagctttg ttgaagcagc cttcgcaggc aaataagcag
    23041 ccactaacgt aaagactgtt gcggacacct tcaccatcga caaaattaaa cggtttgtag
    23101 tcagcaatat agttttggct gtagtctttt gctaaccatt cttttggttt tggatttctc
    23161 ataaaaaaac ttctttcatt taaggttcaa agatatagct attgaagata aaatctactc
    23221 gaccacataa ataagaacaa actgacctaa atccattgtt caagaaagct tgttcttatt
    23281 ttgatagagg gcgttcaaag atacaaagcc atcgaaagag ggtggtgaaa aaagacttgt
    23341 catagcctct tattctgaat aaacggtgtt caaaagcttg catctgcagt aataagccca
    23401 actaaacgaa aaatatgagg aactattttt gtttagctat tcttattact tgatgcagga
    23461 cagctttttc acaacctcat ttcatgtgtt tcacacgtga ggaaatttct ttatggcggc
    23521 catgtaccat cggacgagct tgcggatttc ctaaatagcc acaagtacgt ttgactacat
    23581 cacatgtttt tggatcatga tttccacatt ctggacattc gaaccctcgt tctgtcggtt
    23641 tgaaatcacc ttcgaaacca cattgatagc aatgatcgat tggcgtattc gtaccaagat
    23701 acccgatttt gtcatatgca aaatcccata cagcttctaa agctttcgga ttttgttgga
    23761 gcatagggta ttcacagtag tggatgaatc cacctgaaca atattttgga taatccttct
    23821 caaattccaa tttttcaaat ggcgttgggt ttttacgcac atcatagtgg aaactgtttg
    23881 tataatattc tttatctgtg atattttcga tgatgccgaa tttttctgta tccaaacggc
    23941 agaaacggtc agttagactt tcacttggag ttgaatagac actgaaatga taaccatatt
    24001 catcccccca tgcatctgca ttagctttta attctttgac gatatcaagt gtgaaagctt
    24061 ttgcttctgg gtttgtttcc cattcgccac cgaagaaagc tgaagcaact tcatacaatc
    24121 caatgtagcc taacgataca gtagctcgac ggtttttgaa taattcattg acagaatcgg
    24181 tacgtgaaag acgtttcccg aaagcaccat acatatataa aattggcgca tttgctggaa
    24241 tggcttcttt acaacgttct acacgataga gaagcgcatc tttcatgatt tctaagcggt
    24301 cagacagtaa ctgccagaat ttattctgat ctccttttga ttcgatcgcg attcttggca
    24361 aattcaatgt aacaacacct aaattcattc gtccgacatt tacttcttga ccattttcgt
    24421 ctttccaccc ttgcaagaat gaacgacagc ccataggtac tttgaaactt ccagttaatt
    24481 caacgatttt atcgtaattc agaatatcag gatacattct tttcgttgca cattccaatg
    24541 ctagttgttt gatgtcgtaa ttaggatctt cagggtttaa gttcacacct tttttcaaag
    24601 tgaagatcag tttagggaag atagctgtcc gcttttcact ccctaatcca ttgattcgaa
    24661 tctgtaaaat tgctttttga atttctcttt caaaccagtt ttctcctagt ccaaatccta
    24721 atgaagtgaa aggagtttgt ccatttgaag taaataaggt attgatttca tattccaaac
    24781 tttgcatagc atcgaagata tcttttttgg tttttgcttt tgcatattct ttttggcgtt
    24841 ctggcgaatc gatccattct tccgcgtctt ttagatgttt tttatagttc aattctgcaa
    24901 aaggagcaag caattcatct gttcggtcgg cagaacagcc accatattga cttgacgcta
    24961 cattggcaat aatctgtgag atttgtgctg tggcggtctg gatagatttt ggcgattcga
    25021 cttcggcatt gccgattttg aacccattgt tcagcatgcc tttgaaatca atcaagcagc
    25081 aattcgtcat cggtgtataa ggatgataat ccaaatcatg gtaatggata tcgccttttt
    25141 gatgcgcatt tgctatatgt ggtggcaaca ttttcagtcc gattgatttt ccaacgatcc
    25201 cggctgtcag atctcgctgt gtattgaaaa cattactgtc tttatttgcg ttttcgttca
    25261 cgacagtttg gtccttgttg attagctttt caatcgaaaa gttgatatct gttgctttac
    25321 tgcgagcaaa atctcgtttg gtacgataat tgatgtactc ttctgctaat tcatattcgt
    25381 ttttttctag taatatatgt tccacgatgt tttgaatctc atagattttg acattttcag
    25441 caaaccggct tttgatttct tggacaacca agtctgcaat catttgaatt ttttcataag
    25501 taagtggtga taatgagccg tgaattttct tttctgcttt gatcagtgct tcattgatct
    25561 tttgttcatc gaaatcaaca tggcggccat cgcgtttgat gactttcatc tgggatgtct
    25621 ctggctgctg agtaacgaca gttttttctt cataatttac tttcattatc ttcaactcct
    25681 gctaaattgt tcttgtctat cataaaacaa aatcggggaa ggagcaacta aatatcggct
    25741 atatatagta ttcaatgtgc tgtataattg gatttctata ctatatgtag tgtatatttt
    25801 attgtgaaaa aaggtgaaaa cttgtagctg gtggatttgt tttttgcata tttaattttg
    25861 ctgaataaaa taattgaata aaatttttta ttcagtccaa gtaaaagtga caaaaacata
    25921 agagcaaatt attcgtagat atgctactat gcaaataaat agaaatgaaa aatgaaagag
    25981 gaggagaaga attggaaaag atgatcgaag tgaaacatct aagtaaaagc tacggcagca
    26041 aactttctcc cgtcaaagcc ttagataata tctcattcac agtagaagaa ggcgagtttg
    26101 ttgggattat gggcccaagt ggtgcaggaa agacaacgct gatgaatatc ttgtccacga
    26161 tcaatttgcc tacgatgggc agtgtctcga tccaaggaaa agaaatcaca aaaatgaaaa
    26221 acagtgagct cagtgacttt cgtcgaaaaa aactaggatt catttttcaa gagttcaatt
    26281 tgatcgatac cctaaatgca aaagacaata tcctattgcc cctagcagtt gaacggatga
    26341 ctaaagagga aatggaaaag agagtaagac atgtagctca attgttgaat atagaagaac
    26401 tgctcaaacg gtatcccgat gaactttctg tcggacagag acaacgaatt gcagctgcta
    26461 gagcacttgt tgttcagcca caagtgattt ttgcagatga accaactggc tctttggact
    26521 cgaagtcggc tacagaattg ttgaactact tgaagaccat gaatcaaaaa gaaaaagcaa
    26581 cgatactgtt agtcacccat gatccatata cagcaagcta ctgcgataga attttattta
    26641 ttaaagatgg tgtgattttt tctgaagttg tcagaagagg gacaagaaga gagttctttg
    26701 agaaagtaat agacatgcag gcgacgattg gcggaggagg aaaaatgaat gctgtataaa
    26761 ctagccgtta aaagtttttt tcggcagtca cgaggctatc ttgtttattt tttcagtttg
    26821 actttatccg taatgatcta ttattccttc agcgcaatga cctacgatca atctttagtc
    26881 agaagagcaa gtcaagatac ttcgatagat ggtggattga gttttggtgg atttatcatt
    26941 actgttgttt tgcttttttt cgtattcagt gccaaccgat ttttcttgaa tagaaggcaa
    27001 aaggaaatag gcatctatca gctttttggt atgaataaac tgcagatatc aggtatatat
    27061 gtgttagaaa tcatgataat tggattgttc gcctgtattt ctgggatatt actcggtatt
    27121 attttttcca aactcttttc aatgattttg gttcgaatga tggatatgga tcttactagt
    27181 ccatttttta tctccattcc atcagtagta gatactttat ttgctttttt catcatcctt
    27241 ttagcagtat ctgtatattc aatatggaaa atatggcgct atccaatgat tcgaagtttt
    27301 ggagaaaaag aacaagcaga tagttcaaca atgcgcttca ggacaaggca ccgattactc
    27361 gcagtcatcg ggttactact tttaacgagc ggatattttg gagctagtca ttttagggaa
    27421 atcacttcat ggatgatcag ttatcattat cttgatacat tagttttctt ttttcctttt
    27481 ttaatttttt tcgtttgtgt ggtcggtact tatttgtttt tctgttatac atttcggtta
    27541 tttttgatca tattgagtaa atggaagatt tattactatg gtatcaattt tttgataatg
    27601 ggtaacacgc aagttcattt gctcaaaagt tggcgtacaa attctctgat tacagtcatt
    27661 ctcggaattt ctttaatgac aattggcggc acggctagta tctctactat tttatcctac
    27721 caggagaaag tttcctcccc gatggactat cagtttgatg ttgagacaga gaaaaaaatc
    27781 aagccgattc tagcagagga agggcagaag ataactaaag aaatcacctt gcattataaa
    27841 gtcattggga gtatctatag tcaaaatctc gaagaaccta tgtttcaaac tgctaatctg
    27901 atcacggaaa cacaatatca agccttcaga aaagttaatc cagatttgcc gaacatttct
    27961 ttgaaatcac ctggtcatac tgttttgctt gatcaaatgc aaactctttt tcggaatatt
    28021 tcattatatg gatctagtat tggactgcca gataatcaag aattgaagat tcaacaaatg
    28081 cttccaagtg tattaggtga cgaaacaatg gtatatctaa gtcctgtact gattgtagat
    28141 gataccgttt ttgaaaaagc aaaaggtgtg gattatcaag tagtcaatgt agatgtatca
    28201 ggtggaaata atgaaaaaat agatgaacga ctgagcaatg acctgtcgat aaagtggctc
    28261 aatgctgttt attattctta tgatatcgta aatggaagtc tacaaggaga aattagcaca
    28321 aagaaacttc cggatgacca aatgaaggaa gcacaattta gccaagaaag ctctcgtttg
    28381 aatttctctt ccagctattc gaaattgcgt gcagttaatc ggcgaatcgg tatcaatatt
    28441 tttgtcacac tatttgtcgg gatgatcgtg attattgcta ctggtagtat tttgacagtc
    28501 cggcaattag cagaagcaga ggaagaaaaa gaaaattatc acctattgac taagctgggg
    28561 attccacaaa gaaggatcag acggatgatc ttcgagcaaa acgcacttac cttctttcca
    28621 cccatgatat tagggatcac tcacgcagta tttgcaatca atgtcttcac tcagtatata
    28681 aaaactgccg attactggtt ggcttatctt gtgagtggct tattgatcct tatctatctt
    28741 ttgctttatg tcattacgag tcagttatat tgtcggatta tcgaggaatg atatacggaa
    28801 taagacaaga taataaatag aactaaattt tgaataccat ttatttggaa taagaggttg
    28861 tgacacgatt tttgtcacaa cctctttatt ttttatattt tttaaaagta cgagaaatta
    28921 taaagaaaaa agcagtgatt tgatgtgcta tttttataaa agctatgtga caaaactgtt
    28981 agtaaaaaaa cggtttctgt aagctagaca catgtttctt tttgtcaaaa ttagttacac
    29041 tttgtgtgag gttatatgag gagggaatcc aatgaacaaa tggcgttcta atccaaaatt
    29101 gaattattgg ggaaaattca tcattcgaac aattttttat agtgcagtac tgctgttcct
    29161 gatttatctg tatcactata aaaatattca aggaggaact tttatctata acgaatttta
    29221 ggaggaagag tatggaaatc aaaacgatta ttgaagcaat cgatgattgg ggaataaatg
    29281 aacctgatcg agttgcttat caggcggatg agacgcatac ttttggtgaa ttgaaacaag
    29341 catcagacgc acttgcttat tatttagaaa aaaaggtaga aggcgatgga ccaattgtcg
    29401 tttttggcaa tttggagttt gaaatgattg tctcatttct aggggttgtc aaatctggcc
    29461 atgcctattt gccgattgaa gagcatacac ccaaggagcg tatcctatcg atctttcggg
    29521 tggctaaacc atctatggtc atcagtatcg gggactggat agaagatatt ccttcggttc
    29581 ctgtcataac aaaaaaagaa tttcaagaaa tcaagaagat accagtagga ttttatccca
    29641 gaaatagcgt aaaaggtaca gaaaattttt atattatttt tacttctggt actactggag
    29701 aaccaaaagg cgtacaaatc agtcatgata atctagtcag ctttgttcaa tggacgatgg
    29761 aagactttgg gatcaagcct ggtatgcatt tcttagccca agcgccattt tcttttgatt
    29821 tatcggtatt ttctatttat cctgcattag tttctggcgg aatgctgaag ccgttaaata
    29881 aagcagttgt tcaagacttt cgtcaattat tcgcgacatt gccagccttg aagttgaatg
    29941 tgtgggtttc tactccatca tttatggata tttgcttgat ggaacctaca ttcaatggag
    30001 aaaatgtgcc ggaattggac atgtttttat tttgcggaga agaattgacg aaaaaaactg
    30061 cagaaagtct acttgatcga ttcccaaatg cacggatata taatacttac ggtccaacag
    30121 aagcaactgt agctatttca agtattcaga ttgaccagca tgtactagat agttatgacc
    30181 gactaccgat tggctacgta aaaaaagaca cgaaagtttc tattgtccaa gaaggtaaac
    30241 ctgtttcaaa aggagaaacg ggtgaaatca ttattgcagg accaagcgta tcaaaaggtt
    30301 acctgaacaa tcccgaaaag acagctgctg cgttcttttg tcaaaatgac ttagcaagtt
    30361 accatacagg ggatgcaggt agactagatg aatatgggct tttattttat gaaggacgta
    30421 tggatcagca ggtcaaatta catggatacc ggattgaact cggggatatc gaacattatc
    30481 tgctccaaga caaccgaatc aaacaagctg tcgtcgtacc aaaataccaa ggaacaaaag
    30541 tacagcagct ggttgctttt gtcgtattag aaaacaaaac gaaacagccg gattttcagt
    30601 tgactaaatc tatcaaagaa caattactag aagttgtaat ggattatatg attcctcaga
    30661 agttccatta tgtcgatctg ctgcctcaga cagttaatgg aaaaatcgat cgaaaaaaat
    30721 taacagctga ggtgaatcct gaatgatgtt acctcatatg atcccttatg cagagccgtt
    30781 ttattttttt cttttagcca ttgcgcttgt accgatcgtt ctatctttat tgatatggga
    30841 aaaaagatta ccagtttatc aatcagcagt gacacttttc tttttatttg tcagctttgg
    30901 aggtaattat tggcaacagg gagcggcgct gattgggtat gttttgtggc agacgatact
    30961 tgtatggggc tattttgttt atcggcaaag gaaaaatcag acaggatggt tttttgccgc
    31021 cgttatttta gcgataattc cactgttttt aacgaaagtg actccttttt ttgaacatgg
    31081 aaaagcatcg ttacttggtt ttttaggaat ctcttattta acctttaaat ctgtacaaat
    31141 gatcatggaa ataagagatg gcatgatcaa aacatataag ccatttcgtt atatccagtt
    31201 tctgctgttc tttccaacaa tctcttctgg accaatcgat cgctatagga gatttgaaaa
    31261 agatcagctc catccgcctg ttcgtgataa atatgttgat cttttgggaa aaggcgtcca
    31321 aaatattttt gtcggttttt tatataaatt cattatcggt tattattttg gtcaagtact
    31381 gcttcctgta gtgggacgca ttgccttaca gcatggtggt atttcatggg cattagtagg
    31441 ttatatgtac gtgtacagta tgtatttgtt ttttgatttt gctggctata gcttatttgc
    31501 agtcggtaca agctacatga tgggatatca gacaccaatc aatttcaata aacctttttt
    31561 atcatggaat atcaaagaat tctggaatcg ttggcatatg acgctgtcct tttggttccg
    31621 tgattatgta tatatgcgat tgatgttctt catgatgaag aaaaaatttt ttaaaagcaa
    31681 gatcgtaatg tcaaatatcg gttattttgc tttgtttctt ctaatgggta tatggcatgg
    31741 attgacgtgg tactacatcg tatatggact gtatcatgct tgtctgatct gtctgacaga
    31801 tgcatggatc cgatttaaga agaagcataa agagcagttg ccttctaaca aatttacgca
    31861 tggcttagcc gtatttttga catttcaagc agtatgtttt agcttcctga ttttttcagg
    31921 atttttagat aaactttttt ttagctaacg aatagtgaca tattaattta tataacaaag
    31981 gagaaaagga aaatggaaga acaaatttta tcaatcttag aagaaataac aggaacagat
    32041 gaagtaagaa aaaatcgtga tattgatcta tttgatgaag ggttgcttga ttctttagca
    32101 tctgttcaat tattagtcga gctagacgga gagctggata tccaagtccc tgtatctgaa
    32161 ttcgagcgag aggattggag cacaccgaat aaaatcattc aacaagcaac tgcattgaag
    32221 ggttgagtat gaaaaagaaa ctttttgcta ttttcggccc ggttgtttta gctgttggct
    32281 tactgtttgt gttttttacc tcctcctatc aagtagatat ctctaatcca gaaacgatta
    32341 gacgtgcctc ttcttccatg tcagtgaacg tgttgaaagg agatgcgata aaaaattatg
    32401 cattatctga aaaacaatat attccttttt ttggctcaag tgaattaagc agaatcagtc
    32461 catttcatcc gtctgttctg gcagaaaaat accagcgaaa ctatcgtcca tttttgctgg
    32521 gagcacccgg gacacaatcg ttaagccaat atatgatgat gcgttctgca ggagatgcta
    32581 tgaaaaacaa gaaagtcgtc tttattattt ctcctcagtg gttcgttaaa aatggtgtaa
    32641 aaactgatta ctttaatacg tattattctg aacttcaaac atacgactgg ttgttttcaa
    32701 tgaagaaagt aacgcctgct gatcgctatt tagctagaag attattaact ttctcaaaag
    32761 taaaagagaa tgatacgttg acggcgattc tgcaaacgat caaaaaaggg aagctacctt
    32821 tacctgaatc tttgaatcag ctgcgcagcc aatggaacat gctgaagaga gaggatgaag
    32881 tattcagcaa tattgggttg aaagatcgac agcaaaaaat cgatcatgag tcaaaacgat
    32941 taccaaaaca ataccaagaa acagaattat ccattttagc aaatcaaatt ggagaacgag
    33001 aaacgacgaa taatccattc gggttgaaaa acgattttta tacgcatcgt atccgagccc
    33061 acgagccaga gctcaaacag tcacaaaaaa attgggatta tcgtttttcg ccagaatttt
    33121 ctgattttca gctggtcttg gatcaattag caaaaaacca taacgaagta ttgttcatca
    33181 tcccaccggt taacgagaaa tggagcgatt ataccggact atctcaagaa atgttacaag
    33241 gatttgccaa aaagatcaaa tttcaattaa atagccaagg attcaatcga atagctgatt
    33301 ttgtcaatca agcgggtacc aactatttta tggaagacac gatccatcta ggctggaaag
    33361 gctggttggc tgcagatcaa cagatcagac cgtttttaga agaaaatcat attactgcta
    33421 gtaagtatca tcttgacgat gcttttttta gcaaatcttg gcaacatcaa ataccagata
    33481 aactacaatt aaaataaaga aaacaggcga gtgttgctcg cttgttttct ttatttttga
    33541 atattctgaa taaaagataa aaataccaag tttgcctgaa caaaaatcat aagcaatggt
    33601 ataatcacaa tatgaatata gaaatggggg aaaacatttg gatacaaaag aagaacagct
    33661 acttattgat ttaacttctg caaaaggagt acctggaaat gaagaagagg taagagaagt
    33721 attcagagaa tatgccaaac cattcgctga tgatattttt tatgacggtt taggcagtgt
    33781 gattgccaaa catggtgctg gcggaggccc caaggtcttt atttctggac atatggacga
    33841 agttggtttt atggtaacaa aaataaccga aaaaggattc ttggaattcc aaactcttgg
    33901 aggttggtgg gggcaagtca tgcttgctca gcaagttgaa atcaaaacac gtgaagggaa
    33961 aatcgtccac ggtgtgattg gttccaaacc accacatgtt ttaacacctc aagtaagaaa
    34021 taaaccttat gaaataaagg atatgttcat tgatattggc gcatcaagcc aagaagaagc
    34081 caaagagtgg ggcatacgtc ctggagatat ggtcactcca tatattgaat acaaacgaat
    34141 gaatggcagt aaatatttac tggcaaaagc atgggataat cgtatcggga cagctgtttc
    34201 tctgcgagta ttagagaatc tatctaaaga agcacaccca aatgttttat tcgcaggaag
    34261 cgatgtgcaa gaagaagtag gcttgcgagg tgctcgaaca agtacacacc ttgtaaatcc
    34321 cgatattgct tttgctttag atactggtac agcaggagac actccaggaa tgacaccaaa
    34381 agaagcagat tcgattttag gaaaaggccc acagattttg atttttgatg catctatgat
    34441 cccgcataaa aaattattga attttgttat tgatgtagca gaggaaatgg atattccatt
    34501 ccaatataca gtgatttctg gcggaggaac tgatgcagga caaatgcatt tgacaagaga
    34561 tggtgttccg tctgtagcca ttaccgttcc tgttcgttat ctgcattccc atacatcagt
    34621 gattcatgaa gatgattatt tgaatacagt gaaactagtc acagaattag tgaaacggct
    34681 tgatagtgaa acagttgaaa aaattcggag ttatgaataa tgaataatag aatacctatt
    34741 tctgaatatc ggaaaaaagc acgagtttct ttggaaaatc aatggggaat caatacttgg
    34801 cttgttttct tatctataat atttacgagc gtcatccaga acttttttga cggtttcagt
    34861 ccttttccgg aagaaagcat gcagcagcac ttattgagtt ttctagtcga taatttactt
    34921 ttattcgcat tcaactatgc attgttttac attgcgctag tagttgtacg gggtggcaga
    34981 ccaaaaagta accttttatt ttcagttttc caaagaaagt attttggttc gatacttggc
    35041 atcaatttga tcaattcagt catcaactgg ctactcaaca gtttaatctt tctgcccatg
    35101 tttttaatca gcggagtgag tacttatatg cagctgcttt tcagttcaaa tgcggtacct
    35161 acgggtgtca tgccagaaga ttttcttgat atcagctttg ttttatcgat gatagggatg
    35221 atttttgttt cagcactcat catgagtatt gttggcggtt tattccaatt tgctgcatgg
    35281 acaaagttcg actatcctga tttgtcggtt attcaatgtt tgaaatatgg ctggttttta
    35341 ttgaaagata gaattggtac gtatattttg ttgcagctgt cttttatcgg ctggtatttg
    35401 ctaggagcaa tcgctttgtt catcggtctt ttgtgggtca ttgtttatgt gaatgtgtca
    35461 gttgcagaat tttatgaaca agcacggatt gaaaaaggag gtccagacgc ctattttact
    35521 tagcatgtaa gcagtttatt catcaaaaaa ataacttttg tggtaggata aatctttgag
    35581 ggggaatgta cgatgaaatt aactgtttta ggatgcttag gagcgtatcc ttataaaaat
    35641 caagggacaa caggttattt gcttcaatct gacgggttca atttgttgat cgatgcaggt
    35701 agtgctacgc tgatcaaatt acaagaacac cttgatccac ttgatctaga tgctgtgatc
    35761 cttagccatt atcatcatga tcatattgct gaccttggtg tattacagta ttactggcaa
    35821 cttcatccta agagaaatcc ggagacattg ctttcaattt atggacacac aaaagattcc
    35881 attcactttg aagaattgac gttggaaaat gtctcaaaag gacatcctta ttttgaagct
    35941 gaagaattaa aaattggtcc ttttctgatt acttttatgg aaacaatcca tccagtagta
    36001 tgttacgcca tgcgtatcgt agaagaaaca acggggaaag tattcgtatt tacaggtgat
    36061 tcaggttatt tggaaagttt cgctgatttt gcgaaagatg ctgatttgtt tctagcagat
    36121 acctatcttt ttgaaggaaa tgaacatcat catgcccatt tcacttcaaa agaagctgga
    36181 gaacttgcga aatcagctaa cgtaaagaaa cttgtactta cacacctacc tcagtttggt
    36241 gatttagaac aattgaaaaa tgaagcgcaa aaggcagcag gcaaagggat tgatatagaa
    36301 cttgctgcag ttgacaaagt gtttaacatt taggaggaag aacatgattt ttgtaccaaa
    36361 tgaaaaccac gacccaagaa tcaatttagc aattgaacaa tatttgctgc aagaaatgcc
    36421 tttagatgaa cctattttgc tcttttatat caatgaacct tcaatcatca tcggcagaaa
    36481 ccaaaatacg cttgaagaaa tcaatcgaga ttatgtggaa gaaaatggca ttcatgttgt
    36541 ccgtcgctta agtggaggcg gagctgtcta ccatgatttt ggaaacctga actttagttt
    36601 tatcatgcct gatgatgggg attcattccg tgactttgcg aaagtaacac agccaatcat
    36661 ccaagcactt catgaattgg gtgttgctgg ggcggaattg aaaggccgaa atgatctagt
    36721 cattgatggc atgaaatttt ctggcaacgc gatgtatgct accaacggtc ggatgtttgc
    36781 tcatggaaca attatgttcg actctgatat caatgaagta gtcaatgcat taaaagtaaa
    36841 aaaagacaaa atcgaatcaa aaggaatcaa atcgatccgt tctcgtgtaa cgaatatcaa
    36901 accatttctt ccagaagaaa agcaaaaaat gacaacagaa gaatttcgtc aagaaatctt
    36961 gttgaaaatt ttcggcgtag agtcagtaga agaagtaaaa acgtacgaat tgactgatga
    37021 agattggaaa aaaatcaatc gaatctctga ggaatattat cgaaattggg attggaatta
    37081 cgggaagtct ccagatttca atttctctcg ccaaaaacgt ttttctatcg gttcgattga
    37141 agtccatttg aatgtctcag aaggaatgat caaagaagca aaaatctttg gcgatttctt
    37201 cggactagga gatatctctg acgtggaaaa aaaattggtt ggacagaaat atgataaagc
    37261 atctctatca aaaatagtca gccaaattga tgtgaagaaa tattttggtg cgatagaacc
    37321 agaagaattg cttaccttac tttattgaaa ataaaaaata gcggaatcca catatatgga
    37381 ttccgctatt ttttatacag gattcgggta atttcgagag agttgaacag tgatccgatc
    37441 aatgaaagta tctttttcct gcgttagtgt tcctgtgtaa cgatccgcta cgtctttcat
    37501 catcattaag tcaaaacgtt cctgatcatc taattcttct gtgatgcctc gactaaatag
    37561 gtttgtatcg taatgtgcac tatgttcgca acaaatgacg aaatgttcct cttgttcgtg
    37621 tatcgacaaa taaatttttc gatacagtgg attttcgatg gcatgagttt ctctaaagga
    37681 atgctctaaa gcgtggatca aaagttgagc cagatcgtca tcgttgatag gaagttcttc
    37741 gggaagatct gcttggaagg ttatctgaat attccgtttg gcagctaact tctggtaacg
    37801 cgctaagata agatttgtca cctggtggtt gcaaaaagaa cacagcattt cgaaattttt
    37861 tgcttcttct aatatctttt ccacatagtt tttagctttt gtttggtccg tatgcattaa
    37921 atcttgcaga ttctccatct cttggacaaa ttccaggcga agtgtattta cttcttggat
    37981 atgctgtcga agctgctcat aatgttgctc caacaaatca tttttgattt ttaagaaatc
    38041 tacttgtctc cgatctttgt cggtatttaa gatgtgatcg attagattgt agctgataat
    38101 aacgattaga atgataatat ataaaatcgt agaccaattg atcgttgttt gatagatacc
    38161 taatgccgtt tggatgtaaa tcaagcaatg gataatggct accaagacga tccaaggtgt
    38221 acaagctaca taaaaacggt tattcttata tgcttcgcca atgcatgcaa gtgaagtgac
    38281 taaagtgctt ataacactag caatattagc aatcggcatt aattcaggaa gttctgcagg
    38341 agtaaaagtt gcataaagca gaacgccgat aaaaatcaaa agttggaacg tacaaaaaat
    38401 tccgtaccat tttttatagt aaaacattcg gctccaatag tagcagatga tgaaagctga
    38461 cgttaagata ataaataaat gagataaaaa agaatgaacg aatggttcaa aaagaatacc
    38521 acttaaaata tcttctgata cagcttcaaa tcctaatgcc aaagcaaagc aacttaagag
    38581 aataagtgag tattcaagac gtttttgttt atacatcaag tagatcgtat agaaaaaggt
    38641 ccctatagcg ataaaaacag cgattatcat cgtcaatact tgcggcactg attgtgaata
    38701 aataaaacta atcaatggtc cagttgttcc tagataaact ttcggtggca gtccagcata
    38761 gttctgataa ggagatgaga ctgtaagggt caattttttt ccgatataat ttgctggtaa
    38821 atctatcaca gccaatgaga gtccgggatt gctttcttcc tgataatctt tccgttggta
    38881 taaaatcttt tcgcctagat atacagtaat ccattgatgg tttcctttga ttagtaaatt
    38941 tgcttcgtcc aacggttttt caagtgtcgt ttccataatg aatgtttcgt ctttatccac
    39001 ggtaggaatc gtacgagtgt acttgctgtc aaacttaaaa tcaggatcat cttttgtata
    39061 gaaaacccac gaatctttta tttctttcat ttgattgctg tccgcaggag aaaaaataaa
    39121 ataaaagaaa taagcaattc ctgttaaaaa taacaatgat aatataatga ttatgctcca
    39181 ctttatacgt aaataaaaag attctttttt attatatatg ttattaaaaa aagacataaa
    39241 ggtattcctt tctaaaactt gtaatgttag ggtaaacgtt ttttaaacta acgtcaatta
    39301 tttataataa aaaatgagat aaagatgagg aaatagaatt agaaacatat aattattaaa
    39361 gggaaacatt tttacagcta taatttgaaa aaaatttatc gttattatat gattaagaag
    39421 gattgaataa agaaagaagt tgaaaacgat acctgattac aaaaaaataa cttttataag
    39481 ttctataacg ttgattatat ttttaattct tattcttctc gtcgtcttgg ttccccgaat
    39541 ttttggtttg actccttata ttattgagga caaagaaatg agtccatatt atgcacaagg
    39601 aaatctgata tatgtacgac cgaaaaatac aaatgagatt ttagtcggag atattattac
    39661 atattatgaa aattcaggaa aaaaaatctc gacgcgtcgc gtaatagccg ttgaaaacaa
    39721 ccacgaagat ttttatacaa aagctgatac aaagacttat attgagcctg gagtagtaaa
    39781 aaagagaaat attatcggta gtcccatctt tcagattcca tatattggac tagtcctttc
    39841 aaaaacggca tttgcatgga ttcaggggtt attctttacg attgcttttt gcctaacagg
    39901 aatcacagca tggaatacct ttgtagagtt gaaaaagaag cggagacgaa cacagaaatt
    39961 tttgtaagaa tgttaaaaac ataaatgtat tccagagatc caacgactct tctgaacatg
    40021 aaacacgaga aaacactcat gcagcttgta gatttagtca gttgttcgta taatgtgtga
    40081 agaggaggag tagtatgcgc aatgaaatga tgcatcgtcc tgtagtcaaa gaagaactat
    40141 tggattttat gcgtacccag caaaaaaaat taccgggtga gctaggcaaa ctggaagaag
    40201 aagctcatgt agcagaagta ccagttattc cccatgaaac agttgtattt ttgaaatttt
    40261 tacttggaca gcttcagcct gaacgaatct tggagatcgg agcagctatc ggtttttcat
    40321 caagtgtcat ggccacgaca atcggagaaa acgctcatgt tacgacaatt gatcgtttcg
    40381 atgtcatgat cgagaaagct aaaaaaaact atgaacgtct aggactgaca gataaagtga
    40441 ctttgcttga aggtcaagca gcagatatct tgccggagtt gtctggtccg tatgacttta
    40501 tttttatgga tagtgcaaaa tcaaaatata ttgaattttt acctgaatgc ttacgtttgt
    40561 taagaaaagg tggcgttttg atggtagatg acatcttcca aggaggaacg atcttgctcc
    40621 cagatgaaga gattccccgt ggcaaacgag ctatccatcg taaattaaat gaatttcttc
    40681 gtgttgtgat ggatcatccc gatttgacat cgacaatctt gccattaggt gatggtgtga
    40741 tcttaatgac aaaggaatca gaaacaatcg agttgtgata catgattatg gcagcctgta
    40801 gataatcgat tgaatcgagg gctcaattcg aacttgatgt aaaagtttct atatttgtaa
    40861 gtcaattaaa ggatacagga aatctaaata aacaggagta gcatgaagtc aatgtagctc
    40921 ctgttttcaa ttgataacct tagaacagct gaaggagaat gtctcgtttt aaaagattga
    40981 tttagtagtt gggccaaaat aattcattat ttgctaatta aataactatt tcgtattgac
    41041 agaagcaatt taattatcta taattattga tgttccgctg attcttgtca tagtagctca
    41101 gctggataga gcatccgcct tctaagcgga cggtcggggg ttcgaatccc tcctgtgacg
    41161 ctaaaaaacc gttagaaact gaggtttcta acggtttttc tttgtttttt gtgccaatat
    41221 tgtttgtttt caaaggcaaa taaaataaaa aaacatcctt atcgagtaca attataagga
    41281 gcaaaaaaat aaaactcatc agaaaagagg aagaagatat gacgatacta tctagaattt
    41341 tagtgactct agttgcaatt gaattttttt atatcatgta tatcgaaacg gtgagaactg
    41401 attctgacac gacaagtagg gtttttaaaa tgagtaaaga agagttaagc agaaaatctg
    41461 ttcaaacatt gtttaagaac caaggagtgt acaatggact attaggagtg ggactacttt
    41521 atggagctta tctttcttcc gcatctaaag aaatcacaag tatgctatta atatctattt
    41581 tttttgttgc attatatggc agtttgacta gcgatcgttg gattttactc aaacaaggtg
    41641 ggctagctct gttggcattg ctttctattt tcttataaat atagaaaaaa taagaattta
    41701 tctaacagga aactttgtga aaaatattac tttatctcat gaaatatgat attctaatga
    41761 atggtatttt agaaaatttc atgaaaaagg agttagatag gtgttcaaaa attatgtttc
    41821 ctcactaaaa aaagaatttt caggttatga tctttcaaga tttcagaaag atcttttggc
    41881 tgggatcaca gtagctgctg tagcattgcc tttagccttg gcttttgggg tatcaagcgg
    41941 agctgatgcg gccgcaggtt tgattacggc tatcattgcc ggtatcgtta ttggcggttt
    42001 atcaggcggt ttttatcaaa tatcaggtcc gacaggtgcg atggcagcta tcttgatgtc
    42061 tattgcggca acaaagggaa tgcaaggtgt attgcttgct acttttttag cgggtctatt
    42121 tttacttgca gcaggacttt tccgattagg aacactgact tcttttatcc cagcacccgt
    42181 aattacgggg tttacttcag gtattgctat cattattgca ttaggtcaga tcgataattt
    42241 atttggtgtt cactcggaag gtacaaacgt tattgaaaaa ctaagtagtt atcaaacgat
    42301 aggatttccg ataaacacag cctctttgat catgggaggg ctagtcattt tagggatgtt
    42361 tatctatcca aaaaaatggg cgaaacgaat gcctagttcg ctgctggcta tcattttggc
    42421 aacagcagtt atgctattgt tccatttacc agtagcaact gtgggtaaga ttccacaaac
    42481 attgatcagt agtaatcgtt tgaatatggg agattttagc ttttctgcct tgcaacaagt
    42541 ggcagttcca gctattagca ttgctttatt aggaatgatt gaaagcttgc tatgtggtgc
    42601 ttcggctggc cgaatggcaa ataagccctt agatagcaat caagaattaa tggcgcaagg
    42661 aattggaaat ctgttgcttc ctttctttgg cgggattcct gctactgcgg ccatcgcccg
    42721 tacaagcgtg gccatcaaat ctggtgcaca aactagatta gctggtatga tacatgcagt
    42781 tgtcttactg ctctccatgc ttgtttttgc gccagtgatg tcacagattc caatgccagc
    42841 acttgcaggt gttttgattg tgacggcttg gcgtatgaat gaatgggaaa cgatcaagga
    42901 gctatttact aataaatatt ggtcagcagt tctattgttt atccttacga tgatttgtac
    42961 agttatcttt gatttaagta ttgctatcgt gatcggggtg atcggcggct gtgtattttt
    43021 tgttgtcaaa agcgctgcta tcacgatttc attagaaacg atcgattggc aaagaatggg
    43081 gctgccagaa acggaaaagc tgaataactg gacagtagtg tatattagtg gtccactgtt
    43141 ttttatgtct tcagaaaaac tcaaaaataa attggaagaa ctaaatcatc acgatggtgt
    43201 cattttctcc atgcgaggcg taccaagtat tgatttgacg gcacgtgcag tttttgatga
    43261 atttcaagaa aaagcagagc aaagaggaca aacgattatc tatacttcct tgcagccaga
    43321 agtagaaaaa caactttctc acttgtggga acatacattc acgcatcaac atcaaacagt
    43381 tgctcatgcg ttgacagctt tacatgcgaa atatactgca attagccatt aaaacaatga
    43441 aaaagaacag acaagactgt aaactgaaga ttttatggtc ttgtctgttc tttttaatat
    43501 tgctgtaaaa gtgaagctag tacttgccag tcttgatgga taacaggtac aagggagcga
    43561 ttgtagaaaa tagctgctgg atgaaaaagt ggaagaattc gatagttttt ttctgaccat
    43621 tcgtaggcat ccttttgttc tgttaattgt aagacaggcc ctgtatagag ttgaccatga
    43681 tttttggtaa ccgtatattc tttgccaagt aaacgttgaa gaccaatgtt tccaagtgtc
    43741 gcaattaatt ttggctggac cttcatcagt tcgtaatcca atattggtgc atgcgcaaat
    43801 acttcggaac gagtaggtgt ccgatttgga taaacagttt ctgactgttg tgtccgttta
    43861 ttgatccgat gagtcacgcg atacgggcgg ctccttacag cactggtgat atacacctct
    43921 tctcgtgtta agccagttga agaaagtgcc tgcatcaatt cttttccagc ttgaccgcta
    43981 aaaggaacat gcgtatcaat ctctgttttc cctggggctt ctcccacgag catcagttta
    44041 ggatgaagag gtccttgccc agcgataaat ccttctacag gacggccgtt cattcttaaa
    44101 gaagcttctt gtatcagttc ttttgggtat tccatttatg ctcctccttt ttcttttatt
    44161 ataagaataa aagaaacaca atgcgactat tttatttggt agaactgtga ggatagaaaa
    44221 gcagaagtat tgcttgaatt tttgttttac tttttgattt taaatttagt tgactaacgg
    44281 ttgctgttct ggtaagctag tactgttgta attgtggact ccacagctac aaccgctcag
    44341 aacaagtaat aagcacagca tatgctgtca cttcggatgg cgagtctaag tatatcagaa
    44401 ggaggtgctt tatagcatgt acgcaattat taaaactggt ggtaaacaag taaaagttga
    44461 agtgggacaa gcaatctatg ttgaaaaact tgacgttgaa gcaggagaaa aagttgtttt
    44521 tgacgaagtt atcttagtag gcggagaatc tacaaaagta ggcgctccaa ctgttgcagg
    44581 tgcaactgtt gaaggtactg ttgaaaaaca cggcaaacaa aagaaagtcg ttactttcaa
    44641 atacaaacct aaaaaacatt cacaccgtaa acaaggtcat cgtcaaccat atacaaaagt
    44701 ggttatcgac gcgatcaacg cttaatagcg tttgagaaag aaggcctata tatgatcaaa
    44761 ggaacattta agcgaaatga cgcaggtcag atcgtttcat tcactttgac cgggcatgct
    44821 gatgctggtc cttatggaag tgatatcgtt tgtgcgggtg tttctgcgtt agcgatcagc
    44881 actgtcaacg ggattgcctc attagccggt tttgagccga ttgttgaaat gaatgaagaa
    44941 gaaggcggtt atctttatac cgaagtcact tcaggaatga cacaagaaca aaacaatatt
    45001 gctgagattc tattagaaaa tcttttatta ggattacaat cgatagaagc tgaaaactca
    45061 gaatatatcc aaattaaaac aattaatgat aaataggagg tgcagaccat gttgttatct
    45121 atgaatctac aattatttgc ccacaaaaaa ggtggcggtt ctacatctaa cggccgtgac
    45181 tcagaatcaa aacgtctagg tgctaaacgt gctgatggac aaacagttac aggtggatca
    45241 attctttacc gtcaacgcgg tacaaaaatc tatccaggtg taaacgtggg tatcggtgga
    45301 gacgacactt tatttgcaaa agttgatggc gtagtacgtt tcgaacgtaa aggccgtaac
    45361 aaaaaacaag tgtctgttta tccagtagct caagaagctt aattgaatct tatgattaaa
    45421 gaggttgtga caagactttt gtcacagcct tttttgttta taaaaataaa agttgtagtg
    45481 gaggctacga agtttacttt gtctttttac acttaatatt tttttgccaa tttggaatca
    45541 ggatgttttg ataactatcg ttttcaattg atggaagcta tattgtttgc tatcagtgaa
    45601 ataattatat ggtaaacagt gttctttttc ttgtttccat tataaaaatc gtatcgggat
    45661 ttttcgttct tttaaattga acatttctat ctatccgcgt gttatcaaca aaacaaaatc
    45721 aggtaaatag ttgacgaaac agaaataaat acatagtatt atgttttgaa gcctaagtac
    45781 aatagtctat agaaaaggag cgataccatt ggcaaaacgc attgaccgaa tttatatgta
    45841 tgtcaaagaa aaaaccgctc atttaacaaa ggcagaatat gatcaaggag taacaacaca
    45901 ggaaattgct gaagtgttag ggattcagcg aacaaatagc agtaaagatc tgaatcagct
    45961 agtgcgcgaa ggaaaactga taaagacaga cggacgacca gtacgttaca tatatcaaac
    46021 actcgttacg cacgtaaagc cagttacaaa acatgtagtc agttacaaag aaacgccggt
    46081 ctctgaagaa aaaaatacac tccaaataga tactaaggat atctttgcaa aaatcattgg
    46141 agctaacggc agcatgaaaa attcagtgga acaggcaaaa gctgcgattt tgtatccgcc
    46201 aagaggatta aattgtttga ttacaggacc taccggatca ggaaagactt attttgcaca
    46261 cgcgatgtat cattttgcaa aagcgcatca tgtaatagat gaggaaacgg aactgattgt
    46321 tttcaattgt gctgattatg ccaataaccc tgagcttttg atgagtcatt tatttgggta
    46381 cgcaaaaggt gcttttacag gcgcagatga agaaaaaatg gggattatcg atcaagcgga
    46441 tggcggtatg ctgtttttgg atgagattca ccggttgccg cctgaaggtc aagaaatgat
    46501 cttttacttt atggatcatg gaacttacag tcgtcttggg gaaacaacga aatcccatga
    46561 agcaaatgta cggatcgtag gtgcgaccac agaagaccca ggttcttctc tattagaaac
    46621 ttttgttcgg cgtatcccaa tcaatatcaa acttccggct tttgaaaaac gtcctgcaaa
    46681 tgagaaagtc gatttagtaa aaatcatgat tgcccacgaa gcaaaccgca cgcagcgaaa
    46741 gatttctttg acagaagatg tagcaaaagc attgatcggc agtgtgacct atggaaatat
    46801 aggacaattg aagtcaaata tccagttagt atgtgcacga ggatttctaa atcatatgca
    46861 atcacccgaa atctcgatca caatcgatga tttgacagaa gggattcgta gcggattgat
    46921 tcaattagca agcaaccgca gtgcaatggc agagctttct aaaatattgg agccaaagat
    46981 aactgtagca ccaaatgata cgatcatgaa aatccaatcg gactcctatg agttacctta
    47041 taatctatat gatatcatcg gagataaagc agctttactg aagtcggatg gtttggatca
    47101 agaagcaatc aatcatttca tttctacaga tatcaacatc catctgaagt ctttctataa
    47161 agaccatggt ttttctttta atgcagacag caaattagca gaatttgtag atccgaaaat
    47221 catagaagtg accaatcaga tttatgtaat ggtcaaaaga tctttaccat atgagtttca
    47281 gcaaaacttt atttatgcta tgagcttgca tatcagttct tttttgaaaa aaatcaactt
    47341 aggagaagaa cggcatacga atgataacat ccgtgagatg gcttttgatt ttccagatga
    47401 atatgctgtt gcgaaagaag tgcgtagtta tatcgaaacg tattttcaag tggagattcc
    47461 agaaagtgaa gactattact tgaccgttct actcgtctcg ttacgggcaa atcaagcaag
    47521 cggcagaatc ggtgtagtcg ttgcagctca cggaaacagc acagcaagca gtatggtcca
    47581 agttgtccaa cagttgttag atgcagagaa cgtacgagca gtagacatgc ctttggatat
    47641 ggatccgaaa acagcattgg accgaattga acgcaatgta caagaagtag atgaaggaag
    47701 cggggtcata ctcttagtag atatggggtc ccttgcgtcg tttaattcgc aaattcaaag
    47761 agacactgga attccagtac gtactgttga tatggtaaca acttctctag ttttggaaac
    47821 tgtacgaaag gtctcagtat tagggacaga tctagatatg ttgcatgaat cattgaaaaa
    47881 ttttcgaggt tacgcagaaa tatcttctgt agaatctgtt caggaagcaa aacctattca
    47941 taagaaaaaa gctgttttgg ctatctgcgc atctggcgaa ggtacagcac aaagaatcaa
    48001 agaattgatc gaacgagcgg taaacaagcg tcaagaaaca gaattagaag ttctagcttt
    48061 gtcgattgtg gaagtgaaag aagaactgcc agttatccaa aaagaatatc agatcatagc
    48121 tactactggg attactgatt tgaatatcca agccccattt attcctttag aacgttttat
    48181 tgatcaaaat atcgaagtca ttttggatca gttgctgatg gaatcagaat tggaggaaac
    48241 tgaattcatc tccctagatg aagagtcagc taaaaatacg tgtgttgagt ttatctctga
    48301 taacttcatc tttattaatg gtagtaagtt aatcgatcca atgtggcaat tttctacaca
    48361 aatctctcag acgacgggaa tcggcgatga agaatatgga ttcaaaatca acctagtgat
    48421 gcacacagca ggaatgatcg aacgtattat tcggaatgaa ccattgactg tggaagaaaa
    48481 cgaattgaca aatacaacga atgatcctct ttatagccaa ttggcagcct cagttgttct
    48541 gttggaagat cagataaaag taaaagtgcc gatagaagaa atgtattatc tgctacgtct
    48601 agtccataat cagttagata aaaaagaata cactgtgcca tgaatacaca aaaacgatac
    48661 acttttatag tgtatcgttt ttgtgtattg gttaagaatc ctttaaattc aattagtgta
    48721 tcgtaaaaaa gttggcacgc tttttgctta tagtagtgtg tgctaggagg tggttgttca
    48781 cacagaaatg ataggggttt ctgtgaagta gtgaggaaga aggagttttg cagatggata
    48841 ttcgattggc acgtatagat gatcgtttaa tccacgggca agtcgcaaca gtttggtcga
    48901 agcaaacagg tgttgaacgt atcattgtga tcagcgatgt agtcgctcaa gataaattga
    48961 gaaagtttct actaaaagaa gctgcaccgc cggggatcac agcaaatgta ataaccgtgc
    49021 agaaaatgat tcaaatctat catagtggat tattatcacg agcaaaagtg atgcttttat
    49081 tcaccaatcc ccaagatgtt gaagcggttg tccgctgcgg tgtacagttg aagtcgttga
    49141 atatcggcgg tatgagtttt actgaaggca aatcaatgat taccaatttt gtttcagtaa
    49201 atcaacaaga tattgattcc tttcgttact tgaacagtca agaagtggag ttagagattc
    49261 gaaaagtacc tgctgacagg aaaatccttt tgatggaact actagcgaaa atcaaaaagg
    49321 tgtagcaaga atggttgttg gaaaaggtca aataattctg ttgtaatggt tagcaattat
    49381 taatattttt gaatttgtta caacaaaagt aaataggagg tataaatatg gtagggatta
    49441 tcctagcaag tcatggacaa tttgctgaag gaatcttaca atccggttca atgatctttg
    49501 gcgaacaaga aaacgtcaaa gccgtgattt tgaaaccaag tgaaggtcca gatgacttga
    49561 gagccaaatt ggaagaagcg gttgcttctt ttgataatca agacgaagtg ttattcttag
    49621 ttgatttatg gggcggaaca ccgttcaatc aatcaaacac attattcgaa gagcacaaag
    49681 ataaatgggc aatcgtcagc ggtttgaatt taccaatgtt gattgaagcc tacgcatcac
    49741 gcttttcaat ggaatctgct catgaaattg cagcacacat cattgaaaca gcaaaagacg
    49801 gtgtaaaagt aaaaccggaa gaattagaac cggcagaagc accgaaagca gcagttgaag
    49861 acgcacaacc taaaggagca cttccagaag gaactgtggt cggagacgga aaaatcaaat
    49921 atgtattagc acgtgttgac tcacgtctgt tacatggaca agttgcgaca gcttggacaa
    49981 aagcagtgca accaaaccgt attatcgttg tttcagatgc agtatcaaag gatgatctgc
    50041 gtaagagact aatcgaacaa gctgctcctc caggtgtaaa agcaaatgtt attcctatta
    50101 gcaaaatgat cgaagtagca aaagaccctc gttttggaaa taccaaagca ttgcttttat
    50161 ttgaaaatcc tgaagacgta ttgacagctg ttgaaggtgg cgtagacatc aaagaattaa
    50221 atgttgggtc aatggcgcat tcggtcggta aagtcgttgt aagtaaagta ttgtctatgg
    50281 gacaagaaga cgttgaagcg tttgagaagc ttgaacaaaa aggtgtgaaa ttcgatgtac
    50341 gtaaagtacc taatgattca cgcgataaca tggatgatat tttgaaaaaa gcaaaagctg
    50401 aattagcaaa agcgtaataa ataatattaa aatttatagg aggcttatca tgtctattat
    50461 ttcaataatt ttagtcgtat tagttgcctt tctagctggt atggaaggta ttcttgatga
    50521 atttcaattt catcaaccac tagtggcatg tacattgatc ggtttagtta ccggtaacct
    50581 cgaagctggt atcgtacttg gcggtacgct tcagatgatc gctttaggtt gggcaaatat
    50641 cggtgccgct gtagcaccag atgctgcatt agcatcagta gcatcagcaa ttattttagt
    50701 tttaggtgga caaggtgtta aaggtgttcc ttctgcgatc gcgattgccg ttcctttggc
    50761 tgttgcaggg ttgttcttaa caatgatcgt acgtacaatc gctgttccaa tcgttcattt
    50821 gatggatgcg gctgctgaag aaggaaacat ccgtaaggtt gaaatgtggc acatcattgc
    50881 tgtatgttta caaggggttc gtatcgcggt cccagcagca gcgttgctat ttatcccagc
    50941 acaaactgtg caatcattcc ttgaatcaat gccagcatgg ttaacagatg gtatggctat
    51001 cggtggggga atggtcgtag ctgtaggtta cgctttggta atcaacatga tggctacaaa
    51061 agaagtatgg ccattcttcg ttattggttt cgttgtagct gcaatttctc aattaacatt
    51121 gattgctcta ggtgctttag gtgttgcatt agctcttatt tacttgaacc tttctaaaat
    51181 gggtggttca tcaaataatg gaggcggaag caactctggt gaccctttag gcgacatttt
    51241 gaatgactat taatcttgaa ggaggaaaat aaaatggcag aagaaaaaat caaattatca
    51301 aaaaaagatc gtttagctgt tgcgtggcgc tctaccttca ttcaaggttc atggaactac
    51361 gaacgtatgc aaaacggtgg ctgggcattt tctatgattc cagcaatcaa aaaattatac
    51421 aaaacaaaag aagaacgttc tgcagcatta aaacgtcact tggaattctt taatacacac
    51481 ccatacattg cttctccaat tttaggggtt acattggctc tggaagaaga acgtgcgaat
    51541 ggcgcgcctg ttgatgatgt agcgattcaa ggggttaaag taggtatgat gggtccttta
    51601 gctggtgttg gtgacccagt gttctggttt acagtacgtc caatgctagg tgcactaggt
    51661 gcttcattag ctatgggagg aaatatcctt ggaccaatca tcttcttctt aggttggaac
    51721 attattcgtt gggcattcat gtggtataca caagaatttg gctacaaagc tggttctaaa
    51781 attactgatg acctttctgg cggattgtta caagacgtaa caaaaggtgc ttcaatttta
    51841 gggatgttcg tattagctgc ccttgtacaa agatgggtat caatcaaatt cttaccagtt
    51901 gtatcaactg taaaattaga taaaggtgct tacatcgaat gggataaatt gccttcaggt
    51961 ggtgaaggaa tcaagagtgc atttgaacaa gttaataatg gcttagccct ttctcctgaa
    52021 aaggtaacaa cattacaaga caacttagac caattgattc ctggtttagc tgcattagga
    52081 ttaacattgt tatgtatgtg gttgcttaag aaaaaggttt ctccaatcgt tatcatcctt
    52141 ggtttattcg tagtcggtgt tgttggacac gtcatcggac ttttataatc cataaaaata
    52201 tagctcgggc gttgtcccga gcttttttta tatagtatac tgttcataaa caaatatctg
    52261 gagggagaaa atggttcaat caatcaatac aaaagtagac ttggtaattg atgctacttc
    52321 gtttacgggt ctgacagatt acgggcaaat catgataggt gataatggtt ttgagtttta
    52381 ccatgcgcga gatagacgca aatatatcca aattccatgg gaagaagtgg attatgtact
    52441 agcatcagtc atgctaaagg gaaaatggat tcctcgatat gccattcaaa cgaaaaaaaa
    52501 tggtacatac acattttctt ccaaagaacc taaaaaagtg cttcgtgcga tcagagaata
    52561 tgtagatgaa gatagaatgg tacaatcatt gagtttcttt gatgtagtga aacgtggtat
    52621 tcgtagtatg tttaaacgca agtaaaaaat aaagaaaact tctaagagga ggttttcttt
    52681 atttttttac tttgcagaag aaaatatgaa atagcaaaac caattatttg tcccctttaa
    52741 atcccatatg ctaaaattga ttagcaaaga aggaggttat attatgagtt ggttatggac
    52801 attgattgtt ggagccgtga tcggagcaat tgcaggtgcg atcaccagta aaggaaattc
    52861 gatgggctgt gtaacgaata tcattgctgg actagtcggt tcaagtattg gacaagcgat
    52921 tttcggcgaa tggggaccaa aagctgcagg tatggcactt attccatcta ttttaggcgc
    52981 agtgattttg gtagcagttg tctcattttt ctttggaaaa cgatcataag tttttacaaa
    53041 atagtaaact aaaaggagtt gcagcgagac tgtgactcct ttttggcttt atttatttaa
    53101 aataaaaaga agttttccgg aaatttttat ttaactgtcg tgtacgaaga aaagtttgct
    53161 ataatggaaa aaagcgtgca aagaaagagg gagtttcatt atgatgctac gtgtagaaaa
    53221 attgcgcaaa aaaatgcaag aagaaaattt ggattcattt ttggttacca gtccgtacaa
    53281 tcttcgttac ttaacgaact ttacaggtac gacaggatta gctgttatta ctttggaaaa
    53341 agcatttttt attactgatt ttcgttatac cgagcaggcg gcagcgcagg ctcaagggtt
    53401 tgaaattatt aaaaatgtcg gacctatttt tgatgaggta gcaaacttag tacgcaaaga
    53461 agaactgcac tcattagctt ttgaggaaac aacagtctca tttttagaat attcggtttt
    53521 agaagaaatc atcgatgcgg aattagtacc tgtttcacag atgatcgaag aactcagaga
    53581 agtgaaagat gaagaagaaa tcgctattat cgaaaaagca tgtcatattg cggatatggc
    53641 atatgatcac atcctgaaaa tgatccaacc gggcatgact gagattgaag tcgcaaatca
    53701 actagacttt tatatgcgtt ctcttggcgc ttcaggtgtt tcttttgata cgatcgttgc
    53761 tagcggattg cgttcggcta tgccgcatgg tgtagcaagc aaaaaaatca tcgaacaagg
    53821 tgacttgatc acattggact ttggttgcta ttacgaaggg tacgtttccg atatgacacg
    53881 tacattcgct attggtgatc ctggggaaaa attaaaagaa atttatcaaa tagtcttaga
    53941 tgctcaatta gcagttattg atgctgcaaa accaggaatg actggtgtcc aattagatgc
    54001 agttgctaga gattatattt caaaacatgg ttacggggaa gcatttggac attctacagg
    54061 acatgggatc ggtttagaga tccacgaagg accaaacgtt tcttctcgtg cagaaaagca
    54121 atttgtacca ggaaatgtga tcactgatga accagggatc tacttaccag gaatcggtgg
    54181 agtacgtatt gaggatgact tgttgatcac agaagatgga aatcgtgtgt tgactcgttc
    54241 accaaaagaa ttgatcatct tatagtttca tcaatagaag aagtaagcgt aaaaatcagt
    54301 gttcacagac tttgttatag aaaatcactc gatttaatga tacactatag aagaactttt
    54361 aagctgtaag agataataaa gttgggtgtt ttctccaatt catagcagtt tgcagctgat
    54421 cggcggcagt tttcttacca cgtgatcact atgccgcatc atagagaatt cggatgtatc
    54481 tcgtgcttag gcaaagggag gaataaataa atggcagatg aaaaaaattt gattttaaac
    54541 gcaaaccaag atttaggaga gatcgtgatc gctcctgaag tcatcgaagt aattatcggg
    54601 attgcagctt ctaaagtaga aggcgtatac ggaatgcgcg gaacttttgc cagcaatgtc
    54661 actgaattat taggacgtgc agctcacgga aaaggtgttt acttagcaaa cgaggaagat
    54721 ggcttgaaag tagatcttta ctgttatcta gaatatggtg tttcagttcc taaagtagca
    54781 atggaaatgc aggaacgggt cagccagcaa gtccttttca tgacggatat cgatttatct
    54841 gaagtcaata tccatgtagt agctgttgtt cctgaaaaat tagaacaacc aacaatcgaa
    54901 gaactttttg aagacgaaga ggaagagaat gaataaagaa ttatcaagac acgagattcg
    54961 ggaaatggca ttgcaggctt tatttccatt agacttcaat gcagacctaa caaaagaaga
    55021 tgcgattttc aacgcaatcg aattagacca ccgcgacatg atcaacgaag atgaatcaga
    55081 gtttgttcct gtttatcttg atacgctagt tggcggtgtc tgtgcaaaaa aagatgaatt
    55141 ggataaagtg attgaaaaac atttaaaaaa caattggcac atcaatcgga tctcaaaaat
    55201 ggatttggtg atcttgcgta tcgcgatttt tgaaatgact tatgtgacag atgtaccagc
    55261 ggctgttgct ttaaatgaag caatcgagtt ggcaaaaaca tttagtgatg accgttcacg
    55321 taaattcgtc aacggtgttt tatccaatgt attgaaagaa ttagaagctg gggcgtaagt
    55381 cctagctttt ttctatgaat catcataaac ctgttataaa tcgggaaaat tctatggtag
    55441 aatgaaaaca caaaaaatat ctgggagtgg ttagatggca gaattgatta acggaaaaga
    55501 attagctgaa aaaatgcagg cagagattgc tgaaaaaatc caaaaattga aagataatgg
    55561 tatccatccc ggattagtcg ttttattggt aggggaaaat ccagccagcc aaatctatgt
    55621 aagaaataaa gaacgtgtag caaaagaaat cggaatccat tcattggtag agcgttatcc
    55681 tgagacgatt tctgaagacg aactacttgc agaaattgaa aaatacaatc aagatcctag
    55741 ttttcatggt atattggtcc aattaccatt gccaaagcat atagatgaag aaaagatcct
    55801 gttagctatc cgccctgaaa aagacgtaga cggttttcat ccgatgaatt taggcagact
    55861 ccttgcgggt aaaccggaca agattccttg tactccatac ggcatcatga aaatgtttga
    55921 agcttattct atcgatccgg cgggtaaacg agcagtagtt atcggacgaa gcaatatcgt
    55981 cggtaaaccg atggctcagc tactcttgat ggcagatgca actgttactg ttgctcattc
    56041 taaaaccgaa aatctggctg aactggcaca agaagcagat attttagtcg tagcaatagg
    56101 acgtggacat tttgtcacaa aagaattcgt aaaaccaggt gctgtagtga tagatgtagg
    56161 gatgaatcgt gatgctaacg gtaagctgat cggtgatgtg aaatttgatg aagtggagcc
    56221 tattgcaggc tggatcactc ctgtgccaaa gggtgtaggg ccaatgacta tcacgatgct
    56281 gatgtatcaa accgtaaaat ctgccgaagc ttttggagca ggtgaataga tggcacaaga
    56341 atatttaact gtcactacat taacgaagta tttgaaaaga aaatttgatg ccgatcctta
    56401 tttagaacgc gtatatttaa caggcgaaat atcgaatttc cgtttacgtg ccaatgccca
    56461 tcaatatttc agcttaaaag atgaccatgc aaaaatatct gctattatgt tcaaaggagc
    56521 attccaaaaa ttacgattcc agccaaaaga aggaatgaaa gtccttgtcg ttgggcgtat
    56581 ttcattatat gaagcgggag gttcttatca aatctatgta gagcacatgg agcctgatgg
    56641 aataggtgct ttatatcaag aattggaaga acgaaaagaa aagctgatga aggaaggcct
    56701 ttttcaaggg cctaaaaaaa tgctgccacg tttcccaaag cgaatcgcgg tccttaccag
    56761 tccaagcgga gcggttatcc gcgatatcat cacgacggtg aaaagaagat atccaattgt
    56821 ccaattggtt ttgttcccaa cagttgtaca aggaaaccaa gcagcggaca atgttgtcag
    56881 gaatatccag agagtagaag agatgggcaa tttcgataca atgatcatcg gtcgtggggg
    56941 tggttcgatt gaggatttat ggccgtttaa tgaagagcgg gttgctcggg cgatttatca
    57001 agctaatacg ccggtgattt catctgtagg acatgaaaca gataccacga tcgctgattt
    57061 agtagcagat gttcgggctg ccactccaac agcagctgca gaattagctg ttcctgtttt
    57121 gtcagaagag ttgatgcgca ttcaagaacg gcaagctaga ttgcagcagg cgtttgtacg
    57181 ccagatccag cgcaaacaag aacggttcga gcgtgctcga cgttcctatg tatttcggca
    57241 gcctgaaaga ttgtatgaag gtcagaccat caaattagac cagttgaaac agcgattata
    57301 tcaagctaca cagcaaattt atcatgcgaa agaaaaacaa acgatcgcat taagccacca
    57361 attggaacaa gtggctccgc tttatcgagt taaagcagct cgccaagaaa ctgcttatct
    57421 agaaaaacgc ttagaagaga aaatccaaca atatatgaaa caacagcagc agcgttttgc
    57481 tcaagctgtt caatctcttg atttgttgag tccattgaaa atcatgggaa gaggctacag
    57541 ctatacgacg ttaaatgatc aagtagtaaa aagtgtcacc gagattcatc aaggggattt
    57601 gctgacgatc cattatcaag atggaatcgt taaaggacaa gtacaagaga tagacaaagg
    57661 agaataaaaa tatggaaaat ccaacttttg aagagtcact gcaagaatta gaaaaaattg
    57721 tcatgcagtt agaacaagga gacgttccat tagaatcagc tctagattcg tttaaacgag
    57781 gaatggaatt aagcaaacat tgccaagata cattagctaa agcagaagag accttgacga
    57841 aaatgatgac agaatcaaat gaagaagttg attttgacgg aaacgaggaa agctgagatg
    57901 agattaactg acttttcagc tattcatcta cctgctgtag aaaaagaaat cttgtctttt
    57961 ttagatgagc atacaacgga tagaggactc tatgatgcga tgagttattc agtgaaagca
    58021 ggcgggaaaa gaatacgtcc cttattactt ttaacggccg ttgcttcctt tgatgagcct
    58081 attgatgttc ccgtctatca agtagcagct gctttagaaa tggtgcatac gtattccttg
    58141 atccacgatg atttgcctgc gatggacaat gatgatcttc gtagaggaaa acctaccaat
    58201 cataaagtat tcggcgaagc attagctata ttggccggag atggtttgct tacaggagca
    58261 ttccagctaa tcagtatggc acacttaggt aattctccta agcttctgct gcttcagcaa
    58321 ttagctgttt gtgcgggatc acaaggtatg gttgctgggc aagctgcaga tatcgagggc
    58381 gaatcgaaaa agctttcttt agaagaatta gcatttattc atgaaagaaa gacagggcat
    58441 ttgattcgtt atgccttgct ggctggtggc atattagcga agcaacctga agaaatctta
    58501 ttgctacttc aacgattagc cgaacattta ggtttagctt ttcagataag agatgatcta
    58561 ctcgatgtga ttggtacaac gaaaacatta gggaaaacag ctggtaaaga tgaacgtatg
    58621 gaaaaaaata cttacccgcg tttattaggc ctagaaaaga cacgtgaggc gttggagatt
    58681 gagctgttat ccgccaacaa gatcatagac aaattagaag aggacgtttt ttcttttgat
    58741 ggcgggctga tgcgccagat gatcaagcaa tttgatgtgg agaaatgagg gaaagaatgg
    58801 aaaaagaacg cgtagatgta ttagcggtca aacaaggatt atttgaaaca agagaacaag
    58861 ccaaacgttc agtgatggct ggtttgattt acaacgaaaa aaacgagcgg tttgataaac
    58921 cgggagaaaa aattccagtg agtagtgaat taagagtcaa aggtaaaaaa cttccttatg
    58981 tttctcgagg gggattaaaa ttagaaaaag cactcaaagc atttgatcta tctgttgaag
    59041 gaaaaacatt gttagatatt ggtgcatcca ctggcggatt tactgatgca gctttgcaaa
    59101 atggcgcaaa aatgagttat gctttagacg ttggctacaa tcagctagct tggaaaataa
    59161 gacaagatcc tagagtcgtc gtaatggaaa gagtgaattt tcgttatgca aaacccgaag
    59221 actttacctt aggaattcca gaagttactg ttatcgatgt ttcttttatt tcactaaaac
    59281 tgatgctgcc tccattacat gctattttaa aagaagaggg agaagtgatt gctttaatca
    59341 aaccccaatt cgaagcaggc agagaagctg tagggaaaaa cggaattgtt cgtgaccctc
    59401 agacccatca aaaagtttta gaagacattt tgtcatttgc ggcacaaggt ggatatgatg
    59461 tgctggaatt aagttattct ccgatcacgg ggggagaagg aaatatcgag ttcttggctc
    59521 acttgaggaa agtacccgaa agcggaacaa tcaattcagc tattaatatg gcagaagtgg
    59581 tttcaaatgc acacgaacag tttgaccata aataaattgt aactgtgaaa atcaagtgag
    59641 aagtatgcgg attcttcttt attataccaa ggaaataagc tatcattgat taagaagaat
    59701 atgctaagga gcgaagacgt aatgagaaaa aaagatcggc atcgtttgat tactcgattg
    59761 ttgagtgagc aagatatccg aaagcaggaa gaatttgttg aaatcctgaa aagcaaagga
    59821 atatctgtta ctcaagctac gatttccaga gatataaagg aactgaaact gatcaaggta
    59881 ccggcttcag atggcggcta ccgttatagc ataccagctg aaacaaacga agatgtaaat
    59941 actaaattgg aaaaactatt aaaagacgct ttcgtggcag ttgaccaaat ggaaaaattt
    60001 gttattttga aaacattgcc gggaaatgct tcggcagcag caaatttgat tgataaacgt
    60061 tacaagaaag aattattttc gattatcaat gatgacgata atgttttgat gattacacga
    60121 actgaagacc aggcagtttt attgaagaaa gacttcctgc attaccttta agttgaggag
    60181 cgaatgtgat gctacaagaa atcagtatta ctaactttgc gattattccg gaattgcggc
    60241 tttcttttca cgaaggaatg accgcgctga ccggagagac tggtgcgggt aaatccatta
    60301 ttatcgatgc tttaggtctg ttagcaggag gaagaggttc aagcgattat atacgtcaag
    60361 gagcagaaaa atgtgtgctt gaagggttgt ttgaactacc aaaacaagaa ggattctctg
    60421 aactgatggt tgaattaggg atcgaaacag atgaggacaa tctgattgtt cgacgggata
    60481 tgtccttaac tggaaaaaat gtttgtcgag tgaatggtca tattatcaca ttagctaatc
    60541 tgagaagaat cggcagttat ttagtagata tccaaggaca aaacgaacat caggaactgc
    60601 tccagcctga atcacatctt gctttattgg atcgttttgg agatgtagct ttccaacaga
    60661 agaaaaagag ttatcagcaa gaatatatct cttatcgtga gctggaaaaa agggtacgaa
    60721 aagtgcagca aaatgaaaaa tcctatgttc agagaataga tatgctccat ttccagcaag
    60781 aagaaatagc tgctgctgat ttgcaagtcg gagaagaaga gaaattaaaa gaagaaagag
    60841 aaaaacttag caattatcaa aaaattgctg atggattagc tgcaggttac ggagcactga
    60901 cgaataatga acaaaacagt gtagatggtg ttggcttggc cgtttcagaa ctgcaaggga
    60961 tcgcccatct agatgtggag tatgaagcaa tttatgaaaa tatccaaagt gcttactatt
    61021 tgctgcaaga tgcaatcggc gatatgagtc gtcagattga tttattggag ttagatgaga
    61081 gtcgtttaga agaagttacg caacgtttag aattaatccg acagttgaaa cgtaaatacg
    61141 gcgaatccat tgagtcaata ttggcttact atgacgaaat caccgaagag ctagcttctt
    61201 ctgatttttc agaaggtcaa ttggacaaaa tgaaagagga actagagcaa aaagagcttc
    61261 tacttcagca acaagccgca gatcttcatg aagcgcgtaa aaaaatcgca aaagaattgg
    61321 aaaaatccat tctgcatgaa ttgaaaagtc tgtatatgga aaacactgag tttgaggtac
    61381 gtttcttaaa agaagaaaat agacaattga atcatgatgg atttgaccaa atcgaatttt
    61441 acattacgac caatccagga gagccactga agcctttggt gaaagtcgct tctggtggcg
    61501 aactgtctcg gatgttgctt gctttgaaaa ctattttttc ttctgagcaa ggtgtgacaa
    61561 gtattatttt tgatgaagtg gatacaggtg tgagcggaag agttgcacag gccatcgcag
    61621 ataaaatttc tcaaatatcg aaatactctc aagttttgtg catcactcat ctgcctcaag
    61681 ttgctgcagt cgccgactat caatattata ttgtgaaagc agtgattgat ggacgtacgc
    61741 aaacttctgt ttcagagttg aaaacaaaag aaagagaaga agaaattgca cgtatgctgg
    61801 ctggaagtga gattacaaaa ctcacactcg aacatgcaaa agaactattg aaactcgcaa
    61861 aaaggacctg agccacctcg cagtggttca ggtccttttc agcagctgat agctatattt
    61921 tatttttaca tgacactcat tacagcagtc aatacaacag atccaatcgt taaaatcagc
    61981 attgtccaaa tgacaaattt tgttacttta gcaaaagtac ttgtttgttt tttttcacgc
    62041 attgttttca acctcgtcat taattagttg attcaagtgt acaatctttt ttccatttcc
    62101 acaagagggc ttttttataa aaacttccct ttttttaaat aataggtagt tacgatacaa
    62161 ataaataatg ttaatagaac tagccatata aaggcatcat ccctttcagc aataggtaac
    62221 ttaatgttca ttccatagat actgccgacg attgtcggta tagttaaaat aatcgttaaa
    62281 gaagttaaaa ttttcataat attattcaga ttattcgata cgattgctga aaaagtctga
    62341 ttcatttgtt ctactagttt taattgaatg cgagaagtag tcattgcctg ctctgtttcc
    62401 accaatacat cacgtaaatg atttttcaaa gcatgatttt cttggaaaag tttattttgc
    62461 gctagttctt tcaatgcatc taaattagca gaagtcgctt ctctgaaata aacgaggctt
    62521 ttttggatat ccatgatttg ataaagttgt ttgttttcag tggatacttg aagtttggct
    62581 tccaaagtat cgcattgaga ttgaagcgta gctaaataac tgttgtaaga gagtgtgacc
    62641 tgccaaatga attgaaagaa gatattgaga ttaggcgaaa tatcactttt tggaaaggtc
    62701 tggctaaaga ctttctttaa aaacagtggt tcatgattcg taattgtgat aagcttcttt
    62761 ttgggcgtca aaataataga gagcgggtat gtatccactt gaaaataacc gctaggactt
    62821 gttttagcaa aaggatattg taacaataat aacgctggct ttgtcaactt tgattgattg
    62881 aattcttctg tacgggaatt ttctgcatcg tccaatatgg aagtgatgta atctgacgga
    62941 atttcaaatt gatgtgtcag ctgatgaatc tcttcttgat taggacgttc tacacaatac
    63001 cagatcgttt ggtcagtttc ctttccggta ttacgcagtt tctcattatc taatgtaaaa
    63061 tatttgatca tgattttcct cctgttgcct gtttctttta ttataacgga tagggaattg
    63121 gaatacatgg aatgtgtttg taagatatag aatataactg cataaattta aataaaatga
    63181 aacagttgtg taaagtatat acagtatact tgaagcaacg ataaaaaagg agtttacgtt
    63241 catgggcaca ttcacaccac ttatcttgtt ttggtatatt tacccggtaa tcgttttgtt
    63301 tggttgccaa tttcttgtaa aattattttc gttaaatcgt cgttttaaaa taaaagcccc
    63361 tgatttggcg attccttttt tgtggggcgg tatgcatgca ttgtctagaa atacagggac
    63421 aatttctatc ttaccgtttt tctttatttc tgttttgcta atgggaattt gtattgctgt
    63481 tttccaagca tattattatg aagaaattat ttatccgcgt tatttcaaga tgacttggcg
    63541 tttggttttt ctgttgacaa tcgtcttgta cgctgtcttg atcattgtga acatactttc
    63601 ttacctatga aaaaaataga aaagctgtaa aaagtctttt aaaaggcttt ttgcagcttg
    63661 atttttaaaa aaatgtttat gaataaaaaa agttgttccc ggatttccca gaaaaggtgg
    63721 tagaaagtgg gggattgtgg tagactaatt ttagttagtg gaggaatggg gggctttcaa
    63781 tgttgatggg tgaattccaa cataatattg atgcaaaagg acgtttaatc gtgccctcaa
    63841 aacttcgtga agaacttggc gaaaagtttg ttctgacacg cggattggat ggctgtcttt
    63901 tcggctatcc gatgagcgaa tgggaaaatc tggaagctaa actgaacgaa atgccgttgg
    63961 ctaaaaaaga cgcacgtact tttgtgcgat tcttctattc ggctgccact gaatgcgaac
    64021 ttgataaaca aggacgaatc aatataccca gcacgttaag aaattatgca gctttgacaa
    64081 aaggttgcgt agtcatcggt gtatctaacc gaattgaaat ttgggatgag acacgatggc
    64141 aagatttttc tgcagcagca gaagagaact ttgacgaaat tgctgaaagt atgattgatt
    64201 tcggactata agaataggaa gaggctgact aatgactgaa acatttcaac actatacagt
    64261 catgttgaaa gaaacggtag atggattgaa catcaaaccg gatggcgttt atgtagactg
    64321 tacactcggc ggtgccggac atagtgaata tttattaagc caactaagtt ctaaagggca
    64381 tctgtatgcg tttgaccaag atcaaaaagc aatcgatcac gccaagctgc gtttagcttc
    64441 ttatgtcgaa caaggtatgg tcacatttat caaagcgaac ttcagagaat tagaagaacg
    64501 cttgagtgag catgtagata aggtagacgg cattttgtat gatctagggg tttcctctcc
    64561 tcagctagat gaagcagaac gtggatttag ttatcatcaa gatgcaccgt tggatatgcg
    64621 catggatcag tcagctcctt tatccgctta tcacgtaatt aatgaatatt cctaccatga
    64681 attagtaaag attttcttcc gctatggcga ggagaaattt tccaaacaaa ttgctcgtga
    64741 aatcgaacga gtacgaaaaa caaaaccaat ccaaacaact ggtgagcttg tcgaaatcat
    64801 taaacaagtc atcccagctc ccgcaagaag aaaaggcggg catcctgcaa aaagaatttt
    64861 tcaagctgtg cggattgcag taaatgacga actcggtgcc gaagaggcct ctttagaaca
    64921 ggcaatccgg ttattgaaag tcaatggaag aatcagcgta atcacattcc attcattgga
    64981 agacagaatt gtcaaaagta tgtttaaaga atatagtacg gtacaagatc taccaccggg
    65041 acttcctgtc atacctgacg aattccaacc agaactgaaa gtcattactc gtaaaccaat
    65101 ccttccttca gaggaagagc taacagaaaa caatcgatca cgcagtgcaa agttacgtat
    65161 tgcagaaaaa ataagaatga aagaggagta gaatgatggc agaattaaag aaaatgcaag
    65221 attacgaata tgatttacct gaattggtgg atcagccgga acaacaaatg cctgattctt
    65281 cttcgaatca agaaatcatt cttccacaat caccggcaaa acgattaaag cagatttctg
    65341 ctttggaaaa aattgctgtg gcaagcgtgg cgattgctat tgttgcttta tgtgttttaa
    65401 cagttatgct gcgcacaaat atcagcggag ctgaaaaaga aatcacgtca atacaaacag
    65461 aaatcaatga taaaaagcaa gaaaaaacga gtttagaaca agaaaaaaac gaactttctc
    65521 gtactgaacg gattaaacaa atcgcagaag aaaaaggatt gtctattaat gacgacaatt
    65581 taaggaaagt gaagtaaatg agtcttaaaa ataaaattcg gcggtttatg gaaaagaaaa
    65641 atctaaatcc gatgaacaat cgcaaaaaag taggtatcat tttatttgct acgagtattg
    65701 gattgttctt tttatttgcc gtccgtttct cgtatatcgt tattggaggt catgttgctg
    65761 gtacctcatt agctgaaaaa acaaaacagt tgtaccaagg aagtgaagta gtaaaagcaa
    65821 aaagaggaac gatttatgat cgtaacggtg tggcgctcgc agaagatgcc tcctcttatt
    65881 caattaaagc gatactctca aaaacatata cctctgggga taaaaaactg tatgttgaag
    65941 aaaagaattt tgataaaata gcagaaatcc tgcataagaa tctttctata gacaaaaaag
    66001 atgcactgaa tattttagag gacggcgcaa aaaaagagct gtatcaagtt gaatttggta
    66061 gctatgggaa aaatatctcc caagaaacca agcaaaacat cgaagcggac atgaaaaaag
    66121 aaggtgtcgc tggtctttat tttgtcgacc atcaggctcg gatgtatcca aatggcgtct
    66181 tttcttctca ttttattgga tacgcagttc cagacaaaga tgagaatggc ttagttggta
    66241 aactaggttt ggagtctgct tacaatgata tcttgagcgg taaagatggt aagattattt
    66301 atcaaaaaga taattttcaa aatcctctgc caggtacagt ggcagaagaa gaaaaagctg
    66361 tcgacggaca agatatctac acgactttag acagcagact acaaagttat ttagaaacac
    66421 tgatggatca agtaaatgaa gaatatcagc cagaagaatt gacagcagtc ctgatgaaag
    66481 caaaaaccgg agaaatcttg gcaatgggac aacgacctac tttcaatcct gaaacaatgg
    66541 aaggattgac tggaaaagat gctatctggc gtaatttctt ggtacaagat agttatgaac
    66601 caggatcaac catgaaagtt ttcactactg cagctgctat cgaagaagga gaattcaacg
    66661 agaatgaaac cttccaatct ggaaaaatcc aagtagaaga tgctacgatc aatgaccatg
    66721 actttggtga aaaaggtgtg ctgaccatgc gtcaagctct ttcatggtca agtaacgtcg
    66781 ggatggtcat actggaacag cgattaggcg gacgatggta taactattta caaaaactgg
    66841 gatttggaca aagtactcat tctggattag atgatgaagt aaacggtgct ttacctacat
    66901 taaatattgt cgaccgagca atgagtgctt atggacaagc ggtaggtgtg acgaatttcc
    66961 aaatgatgaa agctttcact tctattgcga ataacggtac aatgattcaa cctcgatata
    67021 tcagcaaagt ggtggatccc caaactggag aagagcgaac aactcaaaca gaagttctag
    67081 ggcaaccttt ttcaaaagaa acaacagaaa aagtccgtga atatatgaga gatgttgtcg
    67141 aaagcgaaaa ctacggtatt gcttatggtg tatatagtgt acctggatac aatgtatcgg
    67201 caaaaaccgg aacagcccaa atcgcttctg atacaggggg atatcaaaca ggagatacag
    67261 cctacctgta ttcgattgtg gagatggttc cttctgaaga tccagactat gtcttgtatc
    67321 taacaatgaa acaccctaag acatatgatc gaatggcatt ggctaaaatc gcaaatccat
    67381 tgatgaaacg ggcaatggat tttaaagaaa ctgaagaaga ttcagataca gaaacaaaaa
    67441 cagaaaaagt atccgtagcc gattatcgta atcttgaagc ggacgttgca gcagctgatg
    67501 ctcaaaaaag tggactgcaa cctgtagtga tcggtaatgg taaaaaagta caaaaacaat
    67561 ctactgccaa cggtgatcag ttgatctctg gagaaaaact gatcctatat actggtggtg
    67621 ataagctgat gcctgacgta acaggatggt caaaagcaga tatcatgaag ctggggaaaa
    67681 tcctcggtat tgaagttagt tttgatggag atggttattg tgtcaaacaa gaacttgctc
    67741 catatgaaaa aatcactgaa gacaaactta gttttacttt agaagaataa gaagagaaat
    67801 aggagagaaa agagcatgga atggacacaa gcattgattc ccattgtcag cagttgtgca
    67861 atgacaattg ccgcaatgcc gctatttatt ggttattttc aaatgaaaaa gcaaggtcag
    67921 gcgattcgtg aggagggacc aaagtggcac aatagcaaag ccggaactcc tacaatgggc
    67981 ggcttagtgt ttctgatcgg ctctattttg acaggaattt gggttggagc ttggcaaaaa
    68041 cagctaactc ctactctttt catcttgctt tttgtattag cgttatacgg agtaatcggc
    68101 tttcttgatg attttataaa aatattcaag aaaagaaaca tgggactgaa ctcgaagcag
    68161 aaattgattg gacagattct agggggaatc atcttttatc ttgtttaccg ttctgaaggt
    68221 tatccaggtg tattgaattt cttcggacta gatctacctt taggaatcat ttatggtatt
    68281 ttcgctctct tctggcttgt tggattttca aatgcagtaa atctgacaga tggcatcgat
    68341 ggattagttg ctggcttagg aagtatctct tttgcagctt acggtctaat tgcttggcat
    68401 cagcatcagt atgatgtatt aatcatttgc ttaagtgttt taggaggttt actgggtttc
    68461 ttcgtctaca acagaaaacc tgccaagatt tttatgggag atgtcggttc attagcgttg
    68521 ggcggacttt tagcggcaat ttctataatg ctaaaccaag aatggacatt gcttttgatt
    68581 ggtttgatct atgttatgga aacagcaagt gtgatgcttc aagttacttc ctttaagctt
    68641 acaggaaaac gaatttttaa aatgtctcca attcatcatc actttgaaat gtgcggatgg
    68701 tcggagtgga agattgatac agttttttgg ttgatcagca ttgtgacttc gttgatcaca
    68761 ttatggatcg tttggtagga gatgacggga aatgaaaaaa atatcaacat atgaaaataa
    68821 gaaagtgctt gtcttaggac tcgcaaaaag cggagtaagt gcggccaaat tattacatga
    68881 attgggcgca cttgtcaccg ttaatgatgg aaaacctttt gacgaaaatc cggaagcaca
    68941 agagctgctt tctttaggga taaaagtaat aacaggtagt catccaatcg aattgttgga
    69001 tgaagaattt tcattgatgg tcaaaaatcc agggattccc tacagtcatc ctttagtagc
    69061 aaaagcccaa gaaatgggta ttccggtaat tacggaagtt gagctagctt acgaagtagc
    69121 ggaatgccca attattggga ttacaggaac gaacggaaaa acaacgacaa caacgatgac
    69181 aggactacta ctgaatgcag gagcagatca aggaattgca cgtttagcgg gtaatattgg
    69241 gtatccagca agtggtgtag cgcaagaagc aaaatcagaa gataaaattg tgatggaatt
    69301 gtctagcttc caactcatgg gaatcacaga tttccgccct catatagcgg tgattaccaa
    69361 tatctatgaa gcacatattg attatcatgg tacaagaaaa gaatatgtca aagctaaatg
    69421 gaaccttcaa aaaaacatga cagaaaaaga ttatctgatc cttaactgga atcagtcaga
    69481 actacaagaa ttagcgcaaa gaacaaaagc acgcgtactg cctttctcga caaaagaagt
    69541 gttggaagac ggtgtgtatg ctgacgatta ctcaatatac tataaaaaag aaaaaataat
    69601 ggaaatatct gaacttggcg taccaggtaa gcataatgta gaaaatgcac tagctgctat
    69661 ttctgtagca aaattgtatg gtatatcaaa tgaagctata cgagaaacgt tgcatttttt
    69721 ccatggcgta ccacatcgta cgcaatatgt aggagaaatc caaggcagaa aattttataa
    69781 tgattcaaaa gcaaccaata ttttagcgac taaaatggct ctaagtggat ttgaaacgtc
    69841 taaggtcgtg ttattggctg gcggattaga cagaggaaat acatttgatg aattaattcc
    69901 ttcattaaaa ggaatcaaag caatggtcgt atttggccaa acaaaagaaa agttgatgga
    69961 tgctggaaaa aaagcaggca tcgagacaat agtaacagcc gattctgtag aacaagcagt
    70021 tcctttagca ttagaaaaca gtacagatgg tgatgtagtt ttattatcac cagcgaatgc
    70081 cagctgggat caatacccaa attttgaaac tagaggaaac agattcatgg aagctgtgaa
    70141 ccgattaaaa tagaaaaagt agaagcgagc gataaaaaat gaaaattttg gttacaggcg
    70201 gaggaacagg gggacatatt tatccagctc ttgcctttgt caattatgta aagactcaag
    70261 aaccgaatgc tgaattcatg tatgtgggag caaaacgagg tctagaaaac aaaatcgtcc
    70321 ctgatacagg aatgcctttc cataccttgg agattcaagg atttaaacga aaaatttcca
    70381 tgcataacat caagacggtc cgattgtttc ttaagagtat ccgtcaagca aaaaaaatcc
    70441 tcagtgattt tcaaccagat atcgttatcg gtactggagg atatgtttcc ggagcggtag
    70501 tgtacgctgc agccaaaatg ggtattccaa cagttatcca tgaacaaaac agtgtaccag
    70561 gtgttaccaa taaattttta agccgatatg tggatcggat cgctctttca tttaaagatg
    70621 cggcttcctt ttttcctgaa aacaaagcag ttcttgtagg taatcctcga gcacaagaag
    70681 tagcagatac taaaaaatca gatattttga aaacatttga tttggatcca gaaaagaaaa
    70741 cagtcttgat ttttggcggt agtcaaggag cacttaaaat caatcaagca gtatcagttt
    70801 ttttaagtga atatattcct tcttcttacc aagttttgta tgcttcagga gatagatatt
    70861 atgaagagat cctaaataaa ataaatcctg aaatacaaaa tattagtgtc cagccttata
    70921 tcaaaaatat ggcagaggtc atggcttcca gtgatctgct ggtggggcgt gctggtgcaa
    70981 cttcgatcgc agaattcaca gctctggggt taccggcagt gttggttccc agcccatatg
    71041 ttacgaatga tcatcagact aaaaatgcaa tgagtcttgt tcacgcagga gcagcaaaaa
    71101 tgattgcaga taatgaacta acaggtgaat cactaagtca gacagtcaac gaaatcatgg
    71161 gtgatgaaga attgcaaaag caaatgtgcc gagcttctaa agaacaagga atccctgatg
    71221 cttcaaaacg tctttatgac ttagtaaaac aaataatcaa aaaataaagg cggtggtctt
    71281 agtgagtaag aaaaaagaac caaaaaaatt gtctcatccg tcttctgatg aaaacaattt
    71341 gactccttgg caaaaggcta accgaaaata tctggcagaa caagagatga aaaaccaaga
    71401 gccaaaaaaa gaagacataa cattagatac acccctttca gattctgaag aagaaaaaac
    71461 ggttcaagag gaacagcaag aagaaagcca gtccgagaaa aaaatcgaat tttttgaaga
    71521 gatcaagcaa aagaaaaacg gtggaccata taacggttct tttttgaacc ggctgcccaa
    71581 tttaaaaagt caacggcaca aagtactatt tcgtcggtta gctttgatca tcactgtatt
    71641 gggtataccg ctgatttttt tgatctatta tgtttctcct tatagcaaat tacaagcagt
    71701 tgcagtatca ggcaataaga cagtcaacag ccaagaaatc atctctgata caaaattgtc
    71761 attaggagaa aatgtttggg gacagtattt tcatcgatct acttatatcg atcgccttaa
    71821 aaaagcacag ccaagaatcg aaacagcaaa tatacatttc aaagggatga atgaattcga
    71881 tttggatgta acagaatata aagagattgc tttgatcgca aaaaacaatc aatactaccc
    71941 agtgattgaa aatggaacag tattagatga aaaagtagca aatcctacaa aaaatctccc
    72001 tatcttggaa gagttcaaag actctgcaaa aatcaaagaa ttaacaaagc aatacaatca
    72061 gttatcatca gaattacaaa aagcaatttc tgaaatcaag tacacgccaa gagcaagcaa
    72121 taaaaatctg atccaattga atatgaatga cggcaatcaa gttattgtaa atatcaataa
    72181 tcttgcgaac caaatgaaat attattcgca agtagccaaa gatatggatg aaaaaggtgt
    72241 gatcgacatg gaagttggta tcttctcgca tccttacggt agcactcaag aaacggaaga
    72301 atcgggccaa tcggaagaaa caactgaaag tgaagaaaat gcggatcaaa caaacgaatc
    72361 aagtgaagag gcagaaacgc aaaaagcaca aacacctgga tcgtctagca caaacggatc
    72421 atctgattca aatgattcaa gtgaaacaag tcaaatagaa gataatccaa gtacaactcc
    72481 gtcaagttta aatgaaaatt gataaaacaa ctttaaaaag taagaatgta ctttctaaaa
    72541 accagtaatt tatggtagaa ttggaagcag tgaatatatc tattaataag tatattttaa
    72601 aacggacgct agttgttcgc ttgtatatgg aatagtaagt aggagggaat cccattcatg
    72661 gcaaaaacag gaatgtatgt aggccttgat attggaacga catctgttaa agttgtcgtg
    72721 gctgaatata tcgacagcca aatgaatatt attggagtag gaaacgcaaa atcagaaggg
    72781 attaaccgag gcattatcgt tgatatcgat aaaacggtcc aagcgataca acgagcagta
    72841 cgacaagcag aagaaaaagc aggtatccag atcaaaggcg taagtgtcgg tttgccagca
    72901 aacatgcttg aagtagaaaa ttgccaggga atgattgcag ttaacggaga ttcaaaggaa
    72961 atcaccgatg aagatgtcag aaatgtggct tcagctgccc ttgttcgttc aatacctcct
    73021 gaacgtcaaa tcgtgtcaat attgccacaa gattttactg tcgatgggtt cgagggaatc
    73081 aaagatcctc gtggaatgat cggcgtaaga ttagaaatgt acggtctgtt gtttacagga
    73141 cctaaaacga tcatccataa catacgtaaa tgcgtggaaa atgccggatt aatcgtcaac
    73201 gaaatggtga ttactccttt agcgctgact gaatcaattc tttctgacgg agaaaaagat
    73261 tttggtacga tcgtcattga tatgggtggc ggccaaacaa caacggctgt tatgcatgat
    73321 aagcaattga agtttaccaa tcttgaccaa gaaggtggcg aatttgtcac taaagatatc
    73381 tctattgtat taaatacgtc atttaacaat gcagaagcgt tgaaaataaa ctacggggat
    73441 gcatacccag aacggacatc accagatgaa gaatttccag tagatgtgat tggtcagtca
    73501 gaaccagtga aagtcgatga acgctacttg tcagaaatta tttcagctcg aatggaacag
    73561 attttcaaca aagcaaaaga tgcattggac caaatcgaag cattagagtt gccaggtggc
    73621 gtcgtattga caggcggagc tgctagtctt cctggtgttg tggacttggc acaagaaatc
    73681 ttcggcgtaa atgtaaaatt gtatgttcca aatcacatgg ggctgagaaa cccggtattt
    73741 acaaatgtaa taagtatcgt ggattattca gcaaacttga gtgaagtgta tcaattggca
    73801 aaaattgctg ttacgggtga aacctcagca gctcgtcaaa tggtagttga acaagaaaca
    73861 acaaacacat atgagagcta tgaagcacct gaagaaacaa tctacgatga gccggaacca
    73921 aaagagtccg gagaaaatgt aaaaaataaa atcaagggtt tctttacaaa tatttttgat
    73981 taattcatcc tgggaggaat aagatatgga attctcaatt gataataata tcaatgacgg
    74041 cgcagtaatc aaagtcatcg gagtcggtgg tggcggtgga aatgctgtaa accgaatgat
    74101 tgaagaaaac gttaaaggtg ttgaattcat tacagccaac acagacgtgc aagcattaaa
    74161 aaattcaaaa gctgaaacag ttatccaatt aggccccaaa tatactcgtg gtttaggtgc
    74221 tggttctcag ccagaagttg gacaaaaagc ggcagaagaa agtgaacaat ccttacgcga
    74281 agctttagac ggtgcagata tgattttcat cactgcagga atgggtggag gaaccggtac
    74341 aggtgctgca ccaatcgttg caggtatcgc gaaagaattg ggcgcattga ctgttggtgt
    74401 cgtgacacgt ccattcactt ttgaaggacc gaaacgtggc cgttttgctg cagaaggtat
    74461 cgctcgtttg aaagaaaatg tggatacatt attaattatc tcaaataacc gtttattaga
    74521 agttgtagat aaaaagacac cgatgcttga agctttccgt gaagcagata atgttttacg
    74581 acaaggtgta caaggtatct ctgatttgat cacagcgcca ggttacgtta accttgactt
    74641 tgctgacgtg aaaacagtga tggaaaacca aggtacagca ttgatgggga tcggtgtggc
    74701 tagtggagaa gatcgcgtag tagaagcaac gaaaaaagca atctcctctc cattgcttga
    74761 aacatctatt gatggagctg aacaagtact tcttaacatc acaggcggtt tggatatgac
    74821 attgttcgaa gcacaagatg cttcagatat cgtagcaaat gcagcaactg gcgatgtaaa
    74881 tatcattcta ggtacatcta tcaatgaaga aatgggcgat gaaatccgtg tgacggtcat
    74941 cgcaacaggt atcgatgaat caaaaaagga acgcaagtct agccgaccag ctagacaagc
    75001 acaaatgcaa tcacctgctc aaaagactgt attagatatg gatcaagcta aaccaacttc
    75061 ttcagaagaa gaaaacagtt ttggcgattg ggatatcaga cgtgaacaaa atgttcgtcc
    75121 tagagttgat gattccaatt ttgacaatat cgaaaaaaaa gaatttgata cattcaaccg
    75181 cgaagaaaca aaatctcatg gcgatgatga attaaatacg ccaccgtttt tccgtcgtaa
    75241 aaaataaagg agaggaagag cacatgattg ctgacaactt gcagaaaatc aagcaagaaa
    75301 ttcaggattc gtgtgctctt gttcatcgtg atccgaaaga agttacatta gtagctgtaa
    75361 caaaatctgt tgaatccgct caagctgaag aattggttag agctggcgtt atgaattgtg
    75421 cagaaaaccg agtagataaa ttattagaaa agaaacaaga tttatttgat tttcctgaaa
    75481 taaagtggca tttaattggt aatttacagc gcagaaaggt aaaattgatt gtaaatgaaa
    75541 ttgattactt tcatgcgttg gacagtttaa gattagcaga agaaatccag aagcggttag
    75601 agaaagaatt atcctgtttt attgaagtaa atgtttctgg tgaggaatca aaacatggaa
    75661 tttcaccaga tgagctttta ccgtttgtgg aatctttagc tgcctgcaca aaaatcaagg
    75721 ttgttgggtt gatgactatg gcgcctaaag aagcttctga tgagcaaatc cataaagtgt
    75781 ttggtacgct gaaagaattg cgtgatcttg ttcaagcaaa aggttatgcc catgcaccat
    75841 gtagtgaatt aagtatgggg atgagtcaag actttcaaat tgcgattgaa gaaggtgcaa
    75901 catttatccg tgtaggaaca gcgctattca aagacgaata aaggaggaac aaaaatgccg
    75961 cttttaaaca gaggagcaat tgctaatttt ttcggattag ctgatgagga agagtacgaa
    76021 taccaagatt atcctgaaac aacaaaaaag gctgtacagc caactaaaaa aaatacaaca
    76081 cagaatcaat caactcattc tgtatctgct gcgaatactc atgaaaaaca aaaaacggcg
    76141 acttcacgtc ctgtaacgca tgaaagtatt cagccggctg aaaagaaaaa agtaattgaa
    76201 ctacatcaat cacctacaaa aactgtagcg aaagaaagaa cagcttcaag aacctctaca
    76261 caacctaaag caaatcttgc tggaaaaatc actgtaatgg aaccaagagc ttattctgaa
    76321 gctatggcga ttgctaaacg aatcattgct ggagaagcaa ccttagtgaa ttttcattta
    76381 gtagaagaaa aacaagcgag aagaatcgtt gattttctaa caggaacagt ttatgcacta
    76441 gatggagata tcaaacgtgt tggagatgag atttttcttt gtacaccgac tgggatggag
    76501 attgacagtt caaccgctca atcttttgca gatgcgaatt tgtttgatct gtaagaggag
    76561 gaactacgat ttatactatt gcactattac ttcatttact tcaacgggca gcctatttct
    76621 atagcattat cttgatggta tatgcattgc tctcttggtt tccaggcggg tatcaatcag
    76681 ggctaggacg attattagct aagatctgcg aaccgtatat cagtttgttc gatcgtctgc
    76741 ctttgaggat tggacccttg gatttcacaa ttttaggggc aatcctgatc ttgaacttag
    76801 ccgtacaagg tttagcacag atcgttatat ggataactgt ccatttagtt tattgattga
    76861 agcaacaaaa tctttattct cagaatagat aggaggggaa aattttggat gcaaatgtat
    76921 accagcactt tcgggcagat gaacgtacat ttatcgattc ggtaggcgat tggattgaac
    76981 aggttcaagg acaatatgca ccctatctga ccgaatttct tgacccaaga caatcctata
    77041 ttttagaaac actgattcga caaagcagtg atttgcgttt catgttttat ggcggatatg
    77101 aacaggcaga aagaaaaaga tgtttgattt tccccgatta ttacgaacct gtagaggaag
    77161 attttgaaac agcattgtat gaaatccatt atcctagcaa atttgccagc ctaagtcatg
    77221 ggaaaatcct tggaacttta gtgggaacgg ggatcaaacg ctcttacttt ggcgatatca
    77281 tctcggacgg tgatcgctgg caagtattta ttgcaaatga ggtggatcat tttgttgctg
    77341 cacaagtaac aaagattgga aaggttgctg tacgcttgga accaatcaaa tacacagaaa
    77401 tgattatgcc gaaagatagc tggacacaag aaagaggaac agttagttcc atgcgactag
    77461 acagtgtgat ctctgagatt tataatattt ccagacagcg gtccaagcag ctgatcgaag
    77521 ctggtaaagt aaaagtgaac tggacagaaa atacaagacc tgattttgta cttgaactat
    77581 tagatattat ttcagtcaga ggttatggca gagtccagat ccaagaactt gaggggaaga
    77641 cgaaaaaaga aaagtacagg gtactgttcg gtgtattacg taaataaaat aaaaaggtgg
    77701 tttactcatg gctttaactc cattagatat ccaaaataag acattcccga caaaaatgcg
    77761 gggatataat caagacgaag tagatgattt cttagattta gttgttcgtg actatgagga
    77821 attgactcaa agaaatcgag aattagaaaa agcagtcaaa cattctgaag aaaaacttga
    77881 gtacttcaat gaattaaaag atgctttgaa ccaatcaatc atcgtagctc aagatacggc
    77941 tgataaagta aaaacaagtg caagcaagga atccgaagtg atcgttactt ctgcacaaaa
    78001 caaagcagat gagttagttg cgaacgctga aaaacgtgca catcaattaa caactgatgc
    78061 agaagaaaaa gcaagaaaaa tcttgacaga tgcaacagaa aaagcaagac agcttgcgac
    78121 agaaactgaa gatcttaaga aaaaaacacg agtattccat caacgtatca gcttgatgct
    78181 tgagtctcaa ttagaacaag tgaaaagtcc ggaatgggat gaaattttac aaccattctc
    78241 cagctacgtg actgacagcc atgaagtgat caaagaagtt ttagcaaaac agcttgacaa
    78301 tgaaaatgat actgatgtaa actcagacac aggagtcata gaagcaccta tgacggcatt
    78361 tgatacacag gctattgata tctcgatcgt gcctggtgaa aatgaaaacg agtagaacag
    78421 aaaagcactt tgttattctt aaagcgagcc gatgagagtg gaagttcggt aagacactgc
    78481 atggtgaaag atcctctact tgagacctgc ttttccgaaa ttagagtaag aagcagcggc
    78541 tgacctcgtt attggtcaca gagagtttgc actagataga tgcaactaaa tttgggtggt
    78601 accacggcat gttcgtccct tgcggctgaa catgcttttt tgtgtccgga aaacaaataa
    78661 aggagtgtat ggttgaatga aaatgaaaga aaccttgcaa ttaggaaaaa caaaattccc
    78721 tatgcgtggt aatttgccaa accgagaagg cgagtggcaa aaagaatggg aagaaaatcg
    78781 aatctaccaa aaaagacaag agttgaacga aggaaaacct agctttgttc ttcatgatgg
    78841 acctccatat gccaatggta atatccattt aggacattca ttgaataaaa tcagtaaaga
    78901 cattatcatt cgttcaaaat caatgtctgg ctatcgtgca ccatatgttc caggatggga
    78961 tacacatgga ttgccgattg aacaagtatt ggctaataaa ggcgtgaaac gtaaagaaat
    79021 gtccatggca gaatacttgg aaaaatgtcg tgaatatgca ctttcccaag tagataagca
    79081 acgagcagat ttcaaacgcc taggagttgc aggagattgg gaacatcctt atgttacatt
    79141 agatccttct tatgaagctg cacaagtacg cgtatttggt aaaatggctg aaaaaggcta
    79201 tatttacaaa ggattgaaac caatttactg gtctccgtca agtgagtctt ctttagcgga
    79261 agctgaaatt gaatataaag atgtaaaatc tccatctatt tttgtagctt tcaatgtcaa
    79321 agacggcaaa gatattcttg atgaagatac agcttttgtc atttggacga caacaccatg
    79381 gacattgcca gcaaaccaag gtattgctgt aaatccaaaa tttacgtatg tattggtgga
    79441 agccgatggc cgtaagtttg tcgtagcgaa agatttgcta gaaacagtcc aatcagaaat
    79501 cggttgggaa aatgtaacag ttctaaaaga atttgctgga caagaaatgg aatatatgac
    79561 tgcaagtcat ccattctatg aacgtgaatc acttgtgatt ttaggcgatc atgttacttt
    79621 agacgctggt actggattag tccatactgc tccaggacat ggggaagatg actatatcgc
    79681 tggtagcaaa tataaactat ctgtagtgtc acctgtagac tcaaaaggat tgtttacaga
    79741 agaagcacct ggatttgaag gtatctttta tgacaaagca aatcctatga tcactgatct
    79801 attaaaagaa aaaggagctt tgctgaagct agatttcttt actcatagtt atcctcacga
    79861 ttggcggacg aaaaagcctg tgatctatcg ggcaactcca caatggtttg catctatcga
    79921 taaattccgt cagaatattt tggatgaagt agaaaaagta gagtgggtta tcccatgggg
    79981 taaaacacgt ttgtataata tgatccgtga ccgcggcgat tgggtaattt cccgtcagcg
    80041 tgcatgggga gtaccacttc cgattttcta tgctgaaaat ggagaagcaa tcatcacacc
    80101 agaaacaatc gaacatgtgg caaaattatt tgctgaacat ggatcaatta tctggtttga
    80161 aaaagaagcg aaagaacttc ttcctgaagg atttacccac ccaggttctc ctaatggcga
    80221 atttacaaaa gaaaaagata tcatggatgt ctggtttgat tctggttctt ctcatgaagc
    80281 tgttttacgt cagcgaccag aattatcatt cccagcagat atgtatttag aaggatcaga
    80341 ccaatatcgt ggctggttca actcaagtat cacgactagt gtggctatca atggtgtagc
    80401 accatacaaa tcagttattt ctcaaggatt tgctttagat ggtgaaggcc gtaagatgag
    80461 taaatcttta ggaaacatca ttgcaccaga aaaagtgatc aaacaatttg gtgcagatat
    80521 ccttcgctta tgggtatcta gtgtagatta tgaagcagat gttcgtgttt ctatggatat
    80581 cttaagtcaa gtggcagaag tatatcgtaa aatcagaaat acgatgcgtt tcttattagc
    80641 gaatacagaa gatttcgatc ctaaaaaaga tactgtttcg tacaatgatt tacgttctgt
    80701 agacaaatat atgaccgttc gattgaacca agtaatcaaa gaaatccgag aagaagggta
    80761 cgacaaatat aacttcatgc atatttaccg tacagttatg aacttcttga cggttgatct
    80821 atcgtcattc tacctggatt ttgctaaaga tgtagtttat attgaagcag aagatgatta
    80881 tcaacgtcgt tgcatgcaaa ctgttttcta tcaaacagct gtagctttga caaaattatt
    80941 gactcctatc attccgcata cagcagaaga aatctggtca ttcctgaaag aagaagagga
    81001 gtacgttcag ttaagcgagt ttcctggtta tgaagagttt gcaaaccaag aagaattgat
    81061 ggatacctgg actgctttca tggacttccg tgataatgtc ttaaaagcat tggaagaagc
    81121 aagaaacagc aaattgattg gtaaatcttt ggaagcaaaa ctaactgttt atccaaaaca
    81181 acaagttcgt gaaatgttaa aagctttgga tgcagatatt gcacaattat tgatcgtttc
    81241 accagactac tttgaagtta tggcagcaga tgaacaagtg ccagataacg ctatggtatt
    81301 tgatgatgtt gctattacag tggaaaaagc agacggggaa acttgcgatc gctgtcgcca
    81361 agttcgtaaa gatgtaggag tagatgaaaa acttcctcat ctatgcggtc gttgtgcaaa
    81421 aatcgttgaa gacttctatc ctgaagctgt agctgaagga ttcgaagaaa agtaaaaggg
    81481 aaaagggggt gtgacatgtt ctttgtcaca cccccttttg ttatcaatcg tttaattttc
    81541 cacgttcacg ataccagtta tctggttgcc agatccattc gaatccgtct ttttcaagta
    81601 gttcgaaagc tgctttaggt cccattgatc cagctttgta gttgggaaaa tccggttgtg
    81661 tttggtccca agcttttcga atgacatcca cgatatgcca agattgagcg acttcttccc
    81721 aatgagagaa gttcgttcca tcaccattca acgcatctaa tagtaatttt tcgtaagctt
    81781 ctgggctatt ttcaaccatt tctgcactat ttctaaattc caatttgatt ggttccgttt
    81841 caaatccttg ccctacttct ttcccattca aggataaaga aaatccttca gttggctgaa
    81901 tatagatcgt tagaacatta ggtggaagtg tcgtatcgtc acatggttca tcgacagatg
    81961 ttttgaatac attaacagga acttgtttga atacgatgtt gatccgagtc cctttttcag
    82021 tcaaacgttt gcctgtacgt acatagaaag gaacacctga ccaacggaag ttatcgatag
    82081 tgaatttgcc tgcgacgaat gtttcagtct ctgattgagc atccactttg tcttcttcgc
    82141 gatagccctt gaattgtaca ccatccaatt caccttgagc atattgcccg cgaacgaagt
    82201 tttctaacac ttcttcttcg ttataaatgc ggatagcttt caatgctttg atcttttctg
    82261 tacggatttc tttttcggaa aatgctactg gcggttccat tgcaagtaat gctacaacct
    82321 gtaaaatatg attttgcacc atgtctttaa gtgcgccact atgatcgtag tagcccccgc
    82381 gatcttctac accgaggttt tcgccaaaag taatttggat attgtcgata tagcgattgt
    82441 tccattgagc ctcaaaaata ttattggcaa aacggatagc tgagatgttt tggatcattt
    82501 cttttcctaa ataatgatca atcctgaaaa tatcttgttc tgggaatact tctctgattt
    82561 gctggttcaa ttcaaaagca gactggtaat cagaaccgaa cggtttttct atgatcaaac
    82621 gattgaagcc attttttgtc ataatatttt gtgatttcaa atgagaaacg atcgttccaa
    82681 aaaattgagg tgccatagcc aaataataga cacggttacc gtttaattga tagtgtccat
    82741 ctaatcggtc agacaattct tttaatgtct gataatgcgt tgaatcattt acatcatggg
    82801 attgatagta aaaatggctt gcaaaggtag ttgcttcttc atctgaagga ttcaatgcac
    82861 ggattgtttc tttgacaact tcacggtagt gctcatcgct ccagggacgg cgagcggttc
    82921 cgattacagc aaaatgctcg cctaaatttc cttttctgta aaggcggaac aaagacgggt
    82981 acaatttacg ctgggctagg tcacctgtac cgccgaatat cgtaaacaat acattttttt
    83041 cattagacat gtggatacac tcctttatat tttatcgaca aaaatcgtgc tggccgcctt
    83101 aaagctgacg gggattttct ttctatcatt ttggatagtg atcggtcctt cataagctgc
    83161 gatgtcaacg atctcatatt cttcgttgat attcaggtca atagtgacta agtaatccaa
    83221 caattctttt tcatcaagca ctcgtgcgat acgcactttt gtaccgacag gataggactc
    83281 caatgtttgt cggcgttctt catggacaac ttcctctttt ttaggaatcg atcctccatg
    83341 aggacaatgt tcaggatgat tcaaatagtt ttctaaatga tctgcaagat gttccgaagt
    83401 cacatgttcc aatacttcag catcatcatg gacttcattc cagctatagt ctaaatgttc
    83461 aactaaaaaa acttcccata agcgatgttt gcgaatcaga ctgctagctt tttgcagtcc
    83521 gcttgcagtc aattgtacac cttgataagg ggaatgttct acaagctctt ctttcacaag
    83581 tttagaaatc atttcactga cagatgcagc tgagacatct agactagata cgatttgttt
    83641 attgttgact ttcgttgtat ctccacctag ttctaaaatg attttcaaat aatcttctcg
    83701 atttggtgtc atattcgatc atcctttcat ggtaaaaaac catcattagt aagtgtaaca
    83761 aaaaaaacgt taattgacta tttttctaaa taaaaaacaa aggattttta gacgttttta
    83821 caacaaaaaa cgaaagatga tagagaagac tcattctttc gtttataaag gatatatata
    83881 tacattggga gggatctatt tttcagataa caacttatat gaagtgtctg cagattcgtc
    83941 ataaagagtt tgttcgggat aagaaaagat aagataaaaa ccatactgat cacgtacgac
    84001 taaacgatat tcatctattt ctaccacaga tgtgccaaga gactgaccgt tgatcaaaaa
    84061 cgtgtaatca gatgtaatct gtaattgttg tttttgctgg ctatcactaa agaaccatgt
    84121 accttgatac tttgagagtc cttctgactt ttccgcttgt tttttctttt tcaagtaaat
    84181 aaaacttgag agaacggtaa tgagtgaacc aagaaaatag atcatttttt ttatcaccaa
    84241 atcactcctt tatgagaaaa taatcgcata gacatattct ttcttcttta tttcattgta
    84301 ccgaataaaa gctaaaattt ctctaagact ttcgactggt ttttttactg tttttctaca
    84361 aattatgata ggatacatag taggaagaaa ggtgacataa tttgaagtat cagcaagtgg
    84421 aaatagcttt ttttattgac cgcccgaatc ggtttatagc acattgtatg aaaaaagacg
    84481 gagaaataat tattgcgcat gtcaaaaata caggtagagg aaaagaggtc ctgataccag
    84541 gcgctgaagt ggctattgta tttgctcctg gacctaaacg gaaaaccgcc tatgatctga
    84601 ttgctgtaaa aaagaagggt gactggttta atatcgatag tcaattgcct aatcggctgg
    84661 caattgatgg tattttagac ggcacgatcc ttttaccagg attaactggt ccatttacgg
    84721 tatacaagcg tgaagtaact tatcttcact ccaaatttga tatttattta gagacggtgg
    84781 tcggacaaaa agcatttgtt gaagtcaaag gtatgacact tgaaaataaa gcgattggtg
    84841 cttttcctga tgcgcccaca ctcagaggat tgaaacatat aggagaatta acgtatgccg
    84901 cacaagatgg ttatgccgct tatgtcttgt ttattgctca gttcgaacat cttcatctgg
    84961 caacgatcca tgaagaaatg caaccagcac tagctgatat ggttcgacat gcgcagcaaa
    85021 gcggagttca aatcctcgcc tataattgtc aagtatcggc agatgaggta actgtcaagc
    85081 aggccattcc atttgatgta gatatccctt ttgaagatcc tatacaatag aaagaaggta
    85141 aaataatgat caacttaggt attatcggaa caaattggat tactcatcaa tttgtccaag
    85201 cagctttaag cacaaaaaaa tatgaattga cagcggtata ttctagacat ttggaaaaag
    85261 cacaggaatt tggttctcat tatgaagggg atatcgaatt cgcaacagat ttgaagactt
    85321 ttttcaatat tactcatatg gacaccattt atattgcttc tccgaatagt cttcacttta
    85381 gtcaagctaa gcaagcaatt ttggcaggaa aaaatgtgat agttgaaaag ccagcttttt
    85441 cgacgccaaa agaaatggat gaaatcatcc atttggcaaa tgaacacaat gtgtattttt
    85501 ttgaagcagc aagaaatatc catgaatcag gttttaaaaa gattgccgat tacttaccat
    85561 taaaagacga gataatcggt gcaaatttca gctatatgaa atattcttcg cgctatgacc
    85621 aagtattaga tggagaagaa ccgaatatct tctcgactca tttctcaggt ggtgcattga
    85681 tggatttagg tgtttacctt gtatatgcag ctgttgcttg gtttggaatg ccaaaagaag
    85741 tccattattt cccaagaaag atttctactg gtgtagatgg tcttggatgg gggatcttac
    85801 gttatgagaa ttttgatgta tcgatccagc caggtaaaat cggtgattct tatttaccgt
    85861 cagagattta ttttgactca ggaacgctag tgatgaatgg agtcaatgca attgaacaag
    85921 cacaatttca tgatcgcgcg cataaagaaa tcattgattt ggcggtaaca gctgcagaaa
    85981 atccaatggc agatgaagca gaggattttg ccaatgtcat ggctcatccg aaagatccag
    86041 cttggggatt gttgtatgaa gagtggatcg agctagctag aaatgtgaac caagtgattt
    86101 atgatttaag aaaaaatggc ggcatcaaat tcgatgcaga taatgaggaa gatttttaat
    86161 gaacgaattt gtacaagtat ttcccgaaaa ttggcagaaa aaatatgagg ataaagggtt
    86221 tatctcacct tctcttattc aacgagcagt ttttcagcca ctaagtaata aacaaagtat
    86281 agtagcggtt tctcctacag gttcaggtaa aacactggct tatctttggc ctctactact
    86341 aaacgtggaa ccaggtgaag caagtgcgtt ggtcattttt gcttcttctc aagaactagc
    86401 tattcaagta gcagatgttg cacgtgaatg gggaaaagac aaagagttga aagtccaatc
    86461 tttggtgggc ggagccaacg tcaaacgtca gattgagggt ttgaaggaaa aaccagaaat
    86521 cttgattggt acaccaggaa gaatattgga attgatgaaa gcaaaaaaaa taaaagcaca
    86581 tcaagtgaaa acaatggtat ttgatgaagc agaccagcta tttgacgctg ggaacagcca
    86641 aatcattgat caaattcttc atcaagctcc aacagagtat cagctagctt ttttttcagc
    86701 gacagcagat cgttcccttg aaagcattga aaaaatcact gggaaaacgt ttgagacaat
    86761 tgacgtgaca gcagaggacg attctcgaaa aggactgaga cattactttt tacgtgtacc
    86821 gatacgaaag aaagatgact acttgagacg tctcacgcat atagaagatt ttcatggtct
    86881 gattttcttt aatcaactga ctgaattagg cgtaatggaa gaaaaattgc tgtatagagg
    86941 tgtaccggta ggaagtctgg cctctgatca gaacaagcta ctccgaaaag cagcgctaga
    87001 acaattcaaa aagaaaatgg tcagagcact tttgaccaca gatgtggcgg ctagaggttt
    87061 agatattaca ggtcttcctt atgtagtgaa tgcagaagtt ccgttaagtg aagaagctta
    87121 tttgcatcgt tcgggaagaa ctggtcgaat gggtaatgaa ggaatagtaa ttacactcgt
    87181 acaagataat aatctaagag atttaaaacg gcttttacgt ccatcaaata taacacttga
    87241 agagattttt ttatacggag gtaagctgca aactgagcag ccaaccaaag aagatgcagc
    87301 tcctgcagta aataaaaagt atgcgaaaac tttttctgga aaggagcaga acccagaata
    87361 taacaaagaa aaaataagaa aaaaagttaa aaataaatca aaaaaagaga gaaataaagg
    87421 agcaaggcgc aaataagcgc ctttttatgc tatgattatg aaaacgggaa caaaattggt
    87481 tgccagagga ggggttatgt gaaagaacgt caagaagaga tcttgcagct attgacagaa
    87541 aaccaacaag gattgacagc aagtgatgta gctgagcgct taactatcga tcgaagcaat
    87601 gcaagccgat atttaagtga actatacaag gcccatcata ttgtaaaaac cgctggccga
    87661 ccagtcgttt actctttgcc aacggaaaag tcaaaatctg atgaagtgca tgtcgactct
    87721 tctacgcaag tgacttttga aacactcgtt ggagaaaatg attctttaaa agtcagcata
    87781 cagcaggcaa aagctgcgat tctttatcca ccgcgggggt tgcatacgat tatttttgga
    87841 gaaactggta cagggaagtc gatgtttgct gaatgtatgt atcattttgc aatcgattca
    87901 gagatgcttt ctgcagatgc gccatttgtt tctttcaatt gtgcggatta tgctcaaaat
    87961 ccgcaactgc tctttggaca catctttggg atcaaaaaag gggcttacac aggagcagct
    88021 caagatagtc ccggtctaat agccaaagca gacggcggta tattgttttt agatgagatc
    88081 caccgtttac cgccggaagg gcaggaaatg ctgtttactt tcattgataa aggtatttac
    88141 cgtccgcttg gagaaagtgc acaagtacat gaagcatctg ttcagatcat tggggcgacg
    88201 actgaatctt cagaaagttt cttatctacg ttcaatcgac ggattcctat ggcaatcacc
    88261 ttgccgaatc ttgcttcacg ttcactggat gagcgttatg aaatcatctc tctttttatc
    88321 aaacaagaag cgaatcgttt gaatcaacgt atcgatatcg aaaaagaagc gattcttgcc
    88381 ttcatgcttt atgatgcgga aggaaatatc ggtcaagtga aacgagactt gaaactagtc
    88441 tgtgcaaaat cttttttaca ttaccgtact catcatgaga aaaagctaat cattcgaaaa
    88501 gaagaacttt cccttcaagt acaaaaagga ttactgaaaa tcaaggaaat accggaacgt
    88561 ctcgaccgat tcatggacag caaaagtcag tatttgacat ttgaaccagg atttgctgat
    88621 gttgtctggt cacaagatcc agaacgaaac atgcaggtct ataacgatat tgaggaaaaa
    88681 gtcacttctc tttccgaaac cggtgtggag aacattgatc tagagaccct catttcaaaa
    88741 gatgtggatg cttatttcca gacatatgtc aaagaattga ctaaaagttc gattcccaaa
    88801 gatcttttgc cagatgaaat ctggcggtta accaatcaat tgtatgatgt ggctgaaaaa
    88861 cggttagacc gtatttataa tgaaaaagct cgttttgctt ttgctttgca tctgcaaagt
    88921 acattggatc gtgtgagaga aggtcatatg atcgtccacc cagatttgaa taacgtacgg
    88981 aaaaatttta agagggaatt ccaggtagca atcgatcttt caacgatcat tgaagaagaa
    89041 gaacaagttg agattccttt tgatgaaatc ggctttatta gtatgtttct ttctatcaat
    89101 ctaggagaaa gtgagcctgt taaagaaaac aaagtagatg ttctcatatt gatgcacggc
    89161 agacagactg cttcaagcat gttggagatg gcacaagaac tattaggaac aaaagtaggg
    89221 aaagctttta atatgccact ggttatggaa gttcaaacaa tgtatgaaga agtgttacaa
    89281 tatgtcaaaa actatcaaga gcatttgacg aatggcctac tcttgttaac agatatggga
    89341 tcattaaaca ccttcagtga tttgatttat gaagagactg gcattcggac gaaagctatc
    89401 acgatgacaa gtaccatgat tgtgatagaa gcgatacgga tggcaagtgt tggaagaagc
    89461 ttagaagata tttatcaaaa tatccagctt tcctttgaat cgatcgtacg tgatcagttc
    89521 aaagcggaaa agtctgaaac tttacagcgt aaaaaagccg taatcgtgac atgctttact
    89581 ggtgaaggag tagctgccaa attatatcag cgtattatgc cagtgattaa tcaaaataag
    89641 gtagaactga tccagatgca gtttttagaa cgtgaatcat tcaaaaaaca catcgatgcc
    89701 ttattggaag aatatgagat caaagcaatt gcgggaacag ttgatgttga ttatcaaaat
    89761 atcccatttt tttcagccta tgacgttttt gatgatgaaa aactaaatat tttaaagcgt
    89821 atagctgatg atgagatccc gacagctaaa attgtcgatt cacttgctgg atcattaagc
    89881 gatgtctttt ctattgatga actgatccgt tcattgcaaa agacagttca gcagatccag
    89941 accgatttgt cgattatcgt ggaacctgga gtagatactg gaatcgttat ccatttagcc
    90001 ttcatgttag acggattgat caaacaagaa agccatcggc aatttgagaa actgtctatt
    90061 ttctcaaaaa tttatcgttt ggaaatggat atcgttcggg caaacttgat ggcactagaa
    90121 cgaaaatatc aggtaaaaat tccagaagat gatatcgcat ttcttacaca aatgtttctt
    90181 gaaaataaaa taaaaaaatg aacacactaa tcatactgtt tacacactaa acatctgtgt
    90241 gcgcactata aaaaagagct aaaaagcatg aaaacgctat ttcagctctt ttttttattg
    90301 gcatgcttct tgcgttatat aaaagtgtaa aaaaataaaa ggagtgttaa aaatggcaaa
    90361 aaaaacaatc atgttagttt gttcagcagg gatgagtacg agtttattgg tcacaaaaat
    90421 gcaaaaagca gcagaagaaa aagggatgga agccgatatt tttgcggtct ctgcctcaga
    90481 tgcagataat aatttagaat ctaagaatgt cgatgtatta ttattaggtc ctcaagtacg
    90541 tttcatgaaa gctcaatttg aacaaaaact tgcgcctaaa ggtattccat tagatgtcat
    90601 caatatgcaa gactatggca tgatgaacgg agaaaaagtt cttgcacaag cagaaaatct
    90661 aatgaaataa atcaagtatg cagttggggg tataacaacg tggaagatca acaaaatcta
    90721 gaagccatca tggggttaat catgtttggc ggtaatgcaa agagcgatgc aatggaagcg
    90781 attgcggctg ctaaaatcgg tgattttgag ttagcggata ggaaaatcgc tgatgcagaa
    90841 gaatcactta tacaagcgca tcatgcacaa acagacatgt tgacacaaga agcacaagga
    90901 aatcatatgc aagtgacatt attgactgtt cacagtcaag atcacttaat gacatctatt
    90961 gcgtttactg atttagcaaa agaaatcatc gaactttatc gtcgcgtata cagcgaataa
    91021 atacaacttc ttttttgaac ggaagaagaa aaatttttga acggattttt tattttgtta
    91081 taaggagaac tctctttata taaaaaactt ataggaggaa gtaaaaaatg aacggactat
    91141 caagttggat ggagaaatac atcctgccgg ttgccgcaaa aatcggagcg caaaaacatt
    91201 tagttgcttt gcgtgatgct tttatcggca cactgcccgc aacaatggcg ggatcagtcg
    91261 ctgtaatgat caatgcaatt attcgtgatt taccgcaaca gtttaacagt acctatgctg
    91321 acagtttagc agcagacaaa ggaatctttg ccgtattgaa tgtcatcatc ggaatcaatg
    91381 gttttgtctg gaacggtaca ctagcaatcg ccggattgat ctttgccttt tcttgggggt
    91441 ataatcttgc ccgagcttat ggagtaaatg atctagctgg ggggatcgtt ggtttagcta
    91501 ccttgattca aggtatttcc tttggtccag cattatcagc agcattagat gtgaatgttc
    91561 cttcaaatgt cgcagatgca atcaatagtt ctgagattgg tgcaacgatt gcagatggca
    91621 cactgtcagt tggattatgg ggttggctaa aactagatca tttgaatgga aacgcttatt
    91681 ttacagttat gatcatggga gctatttcag tcattatttt ttgtaaattg atgcttgcca
    91741 acattacgat caaaatgcct gattcagtac caccagcagt atctaaagca tttgcagcca
    91801 ttttaccagc gacgatcgct ttatacgtca ttgctattat caattatatc gtaggtcgtg
    91861 tagctgatgg gcaactgatc attgatttgg tgcaaaaata tattgcagaa ccattcctag
    91921 gattatctca agggttggga gcagtattga tcgtcacagt atttgttcaa gtattctggt
    91981 tctttggtat tcatggacca aatgtattgg caccagtgct agagggaatc tggggacaag
    92041 cacaactaat caatattgat attttccaaa aaggttataa cggaaaaact ggtacaccag
    92101 ccgtgttaga tgcaatcgaa gatggaaaag cttatatgtg ggtccgcgga tcgttcgatg
    92161 cttttgcatg gtttggcgga tcaggcggaa cgatcgtctt actgatagct atcttgattt
    92221 tctctaaacg tgcagattat ctaacagtag ctaaattatc cattgggcct ggtatcttca
    92281 atatcaacga accagtgatg tttggtctgc caatcgtatt gaatgcaatc atgtttatcc
    92341 cattcttgat tgctccagta gtagcaacag caattggatg gacagctact tatcttggcc
    92401 tagtcgctcc ggtatcgcag caagtcacat gggtagtacc gccgttctta ttgtcattct
    92461 tagcaacagg agcggattgg cgggcaccga tcgtaacatt agtatgtatg gtcgtgactt
    92521 tcttgatttg ggcaccattt gtcatctctg caaacaaaat ggaccctgcc gcaggcgaac
    92581 aacaataaga tgaacgtgag gagcgggacg ctttaagttt cgttcctcat aatgaatttt
    92641 cgaggaggaa ctgaaatgat tacaattgcc agtgcaatgc aacaagatga aatcaaagaa
    92701 ttgttagaag gatacaatga agaaggaatg acttttacat ttaaagaaaa acaaggaatc
    92761 aagctgttct ttgaaacaag tgcagaagat ccggaagttg cggctaaaaa agcaaaggaa
    92821 ctaatcaaag cacagccttg gggaacagtc ctttattttc aatcaacagc tgtttagaaa
    92881 atggtttaaa aagataggat ggttgagatg ataaaaaacg gtttattttt atgtagtatt
    92941 ggttctttga tcgtgttgta tagtttgaat ccacattcgc aaaggtatga tttgtatagt
    93001 atggtcacag gtctttttct aacaggatta ggaatctatt tcttcatgaa ggggaaaaaa
    93061 agagaagaag caaaggagaa aaataactaa tggaaatcac gaaaaaatta aatattccag
    93121 catcgttttt ttacgataaa gttatggact ctgtcctttt cgatgtacgt aaagcgaccg
    93181 gcaaatcagt aactagaaaa cagctgaaaa atttggagta cgtcaaacaa ttctcgcaaa
    93241 ataaccgggc tcgcataaaa atcgaagaag tcattgaaaa ccagtcttat aagtttcgta
    93301 catcgacaac gaagaatgaa ttcgtcgttc attatcaaat caaaccattg gacgattcga
    93361 cctgtgaggt tcattacaca gaaaaaatgg agtcttatgg catgcttcaa aagttgaatg
    93421 atatgctttt aggaacaatc ttgatgtatt ttaaacggag acgtttcaaa aaaatgctag
    93481 atatgatcga agcaacgtat taaatcaatg aaacatggta ctatttagtt attgaaaaat
    93541 gaagtaagct agaaggaatt tttcatagga agatagatct ttcctgcgaa tcctcactag
    93601 cttttttgta ggaaggggca gcaaaatgac aaacaaagta agagagctag gtgtatcttc
    93661 gattgaggaa atgtttgatt tagccactta tgcatttaat ggggcagata cacctgaaag
    93721 gcgagaacgt tttcgtacac ttgcggagaa ttcttggaat tacggatttt ttgatgagga
    93781 ggatcggcta acaagtcaag tcatggcgac cccttttcca gtgaattttt acggacaaga
    93841 gtacctaatg gccggcattg gctatgttgc ttcttatcca gaagcaaggg gacaaggcgg
    93901 gatcaatcag atcatggaaa agatccttga agattgccgt gatcgtaaag taagcttatc
    93961 ttatctggcg ccattctcct atcccttcta tcggcgctat ggctatgaac aatcatttga
    94021 taaaatcagt tatcaactaa acagtcgtga tgtgccgttt atcaaaaaaa aatctggaaa
    94081 aataaagcgt atggattttg aagatgcaaa agctgcaatc agaagaattt atgaacagat
    94141 gccggaaaac caacgagctg gtctgaagcg cgaagactgg tggtatacgt ataaattcaa
    94201 gcaaaaaggc aattaccagt ttgctttgca ttttgatgat aatgaggaag caacgggata
    94261 tatcgtttat cagcttgcaa cgtcttcctt tattattgcg gagtggggat ttttggatca
    94321 tgatgctttt tgcagccttg ttcgcttcgt aagttctcac aatggtgctt ttgaaacatt
    94381 tgaatattca tgcggctacg gcggtaatga tcaaaattat ctattagaaa atccatttgc
    94441 ttctgtaatg atcacacctt atatgatggc gaggatcgta gatatttctt tgtttttgga
    94501 aaattatcca tttaaaaaga gacaagctgc atttgcccta caaatagaag aagatcatta
    94561 tgcgaaatgg aatgaaggaa tcgtggaagt aacaatcgaa aatggaaaaa atcatctctc
    94621 aaaagtagaa caaacaaaac tcccaatcgt tcgaggaagt atccaacata tcacgcagct
    94681 attattaggg tatcgtaaag tggaagagtt ggtattccaa gaaagaatac aggtgacaaa
    94741 agaatatgaa gaaacgttaa gctcaatctt gccacagcaa cagccaattc ttaatgacta
    94801 tttttgataa aaaacgggtg atgacaatat ttttgtcacc acccttttgt ttttcatttg
    94861 gcatttgaag gaaaatgtta aagtaaatcc tcttttttcg taaatttgaa ttttttgttt
    94921 tcttttgttt tagggttttc ttttttgtgg tcttggattg cttctttcgt aatcttttcc
    94981 cgattttttt tagatgaatc taagcgttct gcgtatactt tttcttttgg cttatcattc
    95041 attggaaagg acctccctac attatttcat tctacctcta gtttatcatc tgttaaggac
    95101 tagtggaaac gttttgccta acttataagc tgattttttt agcagataag cttgcaagta
    95161 aaaaacaaac aagctacaat tgatttattg aaattgttcc tgtagctcag taggatagag
    95221 caatcgcctc ctaagcgata ggtcgctggt tcaattccag tcaggaacgt acaaataacc
    95281 cctgtatcct ttgtgataca ggggtttgtt ttgtgtttgt gccaaaaatg tgccaaacta
    95341 gttatcattt ttatataaac tatcgaacac agcattgatt ttttctttat cctgatcttc
    95401 aagctctcga acaatatgaa gataagtaga cattgtagtt tctaaactgc tatgtcctaa
    95461 acgtttcgat acgctaagta tatttactcc ttgataaagt aaaatagatg catgtgtatg
    95521 ccttagtcca tgcaaagtaa attgcttttc aatccctaat tcttttaatt ttttgcgcaa
    95581 atatttgctg acggcgtttg atgaaactaa tccatttttt aagttgaaaa aaacaaaatt
    95641 atgagggttt ttaacttcaa aattctcgaa taattctttt tgattgattt taaacttttt
    95701 taagagatca atcgtatgtt tatcaatgga aattttccta tttgaagttt cgttttttgt
    95761 ttttccccat tcatttaatt tataattcca tgttttatta atagtgatga tttgatcttc
    95821 gaaatcgata tcttcccatg ttaatcctag aagttcagca aatcgcattc cagtagcacc
    95881 agcaactaac acgagcatag gagaagagta ctgcgcagaa aggttttctt ctacgagttt
    95941 cattaaagat ttaaattgat cataatctaa atatttatct tcttttggct tcaatgaatc
    96001 ttttcctttg attactgctt ttctagttgg atcaaacgga attaatcctt cttctacggc
    96061 atctttcaac gatgctctaa tatg
//
LOCUS       DAIGTA010000003        74204 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.003, whole genome shotgun sequence.
ACCESSION   DAIGTA010000003 DAIGTA010000000
VERSION     DAIGTA010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 74204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.003"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(606..962)
                     /locus_tag="NOB43_000191"
     CDS             complement(606..962)
                     /locus_tag="NOB43_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HCI0981100.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /gene="spx"
                     /locus_tag="NOB43_000192"
     CDS             complement(976..1386)
                     /gene="spx"
                     /locus_tag="NOB43_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI0981101.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            complement(1732..3918)
                     /locus_tag="NOB43_000193"
     CDS             complement(1732..3918)
                     /locus_tag="NOB43_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI0981102.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            4136..4819
                     /locus_tag="NOB43_000194"
     CDS             4136..4819
                     /locus_tag="NOB43_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HCI0981103.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(4900..5619)
                     /locus_tag="NOB43_000195"
     CDS             complement(4900..5619)
                     /locus_tag="NOB43_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0981104.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(5931..6137)
                     /locus_tag="NOB43_000196"
     CDS             complement(5931..6137)
                     /locus_tag="NOB43_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981105.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            6382..6984
                     /locus_tag="NOB43_000197"
     CDS             6382..6984
                     /locus_tag="NOB43_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI0981106.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            7125..8405
                     /locus_tag="NOB43_000198"
     CDS             7125..8405
                     /locus_tag="NOB43_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0981107.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            8418..9146
                     /locus_tag="NOB43_000199"
     CDS             8418..9146
                     /locus_tag="NOB43_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0981108.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(9215..10738)
                     /locus_tag="NOB43_000200"
     CDS             complement(9215..10738)
                     /locus_tag="NOB43_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCI0981109.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            10990..12171
                     /locus_tag="NOB43_000201"
     CDS             10990..12171
                     /locus_tag="NOB43_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0981110.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(12231..13859)
                     /gene="treC"
                     /locus_tag="NOB43_000202"
     CDS             complement(12231..13859)
                     /gene="treC"
                     /locus_tag="NOB43_000202"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCI0981111.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(14310..17021)
                     /locus_tag="NOB43_000203"
     CDS             complement(14310..17021)
                     /locus_tag="NOB43_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981112.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(17031..17732)
                     /locus_tag="NOB43_000204"
     CDS             complement(17031..17732)
                     /locus_tag="NOB43_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981113.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            17918..18517
                     /locus_tag="NOB43_000205"
     CDS             17918..18517
                     /locus_tag="NOB43_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0981114.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            18598..19611
                     /locus_tag="NOB43_000206"
     CDS             18598..19611
                     /locus_tag="NOB43_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0981115.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            19719..20636
                     /gene="rbsK"
                     /locus_tag="NOB43_000207"
     CDS             19719..20636
                     /gene="rbsK"
                     /locus_tag="NOB43_000207"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCI0981116.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDALDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            20664..21059
                     /gene="rbsD"
                     /locus_tag="NOB43_000208"
     CDS             20664..21059
                     /gene="rbsD"
                     /locus_tag="NOB43_000208"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCI0981117.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            21059..22432
                     /locus_tag="NOB43_000209"
     CDS             21059..22432
                     /locus_tag="NOB43_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0981118.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            22789..24933
                     /locus_tag="NOB43_000210"
     CDS             22789..24933
                     /locus_tag="NOB43_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0981119.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(24985..26025)
                     /locus_tag="NOB43_000211"
     CDS             complement(24985..26025)
                     /locus_tag="NOB43_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0981120.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26302..28104)
                     /locus_tag="NOB43_000212"
     CDS             complement(26302..28104)
                     /locus_tag="NOB43_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981121.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(28118..28870)
                     /locus_tag="NOB43_000213"
     CDS             complement(28118..28870)
                     /locus_tag="NOB43_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981122.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(28879..29241)
                     /locus_tag="NOB43_000214"
     CDS             complement(28879..29241)
                     /locus_tag="NOB43_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0981123.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(29417..30289)
                     /locus_tag="NOB43_000215"
     CDS             complement(29417..30289)
                     /locus_tag="NOB43_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI0981124.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(30340..30828)
                     /locus_tag="NOB43_000216"
     CDS             complement(30340..30828)
                     /locus_tag="NOB43_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HCI0981125.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(30966..31757)
                     /locus_tag="NOB43_000217"
     CDS             complement(30966..31757)
                     /locus_tag="NOB43_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HCI0981126.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(31812..32420)
                     /locus_tag="NOB43_000218"
     CDS             complement(31812..32420)
                     /locus_tag="NOB43_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HCI0981127.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(32413..32730)
                     /locus_tag="NOB43_000219"
     CDS             complement(32413..32730)
                     /locus_tag="NOB43_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0981128.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(32886..33614)
                     /locus_tag="NOB43_000220"
     CDS             complement(32886..33614)
                     /locus_tag="NOB43_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCI0981129.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            33773..34654
                     /locus_tag="NOB43_000221"
     CDS             33773..34654
                     /locus_tag="NOB43_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0981130.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(34891..35934)
                     /locus_tag="NOB43_000222"
     CDS             complement(34891..35934)
                     /locus_tag="NOB43_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0981131.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(35937..36605)
                     /locus_tag="NOB43_000223"
     CDS             complement(35937..36605)
                     /locus_tag="NOB43_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0981132.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            36747..39083
                     /locus_tag="NOB43_000224"
     CDS             36747..39083
                     /locus_tag="NOB43_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0981133.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(39198..39509)
                     /locus_tag="NOB43_000225"
     CDS             complement(39198..39509)
                     /locus_tag="NOB43_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981134.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            39690..41165
                     /locus_tag="NOB43_000226"
     CDS             39690..41165
                     /locus_tag="NOB43_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCI0981135.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            41212..41796
                     /locus_tag="NOB43_000227"
     CDS             41212..41796
                     /locus_tag="NOB43_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCI0981136.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            41798..42217
                     /locus_tag="NOB43_000228"
     CDS             41798..42217
                     /locus_tag="NOB43_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HCI0981137.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(42498..42782)
                     /locus_tag="NOB43_000229"
     CDS             complement(42498..42782)
                     /locus_tag="NOB43_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HCI0981138.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(43134..43844)
                     /locus_tag="NOB43_000230"
     CDS             complement(43134..43844)
                     /locus_tag="NOB43_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HCI0981139.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(43841..45313)
                     /locus_tag="NOB43_000231"
     CDS             complement(43841..45313)
                     /locus_tag="NOB43_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0981140.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            45451..45924
                     /locus_tag="NOB43_000232"
     CDS             45451..45924
                     /locus_tag="NOB43_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0981141.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(46077..46628)
                     /locus_tag="NOB43_000233"
     CDS             complement(46077..46628)
                     /locus_tag="NOB43_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0981142.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            46733..47263
                     /locus_tag="NOB43_000234"
     CDS             46733..47263
                     /locus_tag="NOB43_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HCI0981143.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(47746..48189)
                     /locus_tag="NOB43_000235"
     CDS             complement(47746..48189)
                     /locus_tag="NOB43_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0981144.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(48205..49365)
                     /locus_tag="NOB43_000236"
     CDS             complement(48205..49365)
                     /locus_tag="NOB43_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0981145.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            49872..51572
                     /locus_tag="NOB43_000237"
     CDS             49872..51572
                     /locus_tag="NOB43_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981146.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(51674..52507)
                     /locus_tag="NOB43_000238"
     CDS             complement(51674..52507)
                     /locus_tag="NOB43_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCI0981147.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(52811..54976)
                     /locus_tag="NOB43_000239"
     CDS             complement(52811..54976)
                     /locus_tag="NOB43_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0981148.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            55236..57530
                     /locus_tag="NOB43_000240"
     CDS             55236..57530
                     /locus_tag="NOB43_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI0981149.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTTHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            57523..58188
                     /gene="pgmB"
                     /locus_tag="NOB43_000241"
     CDS             57523..58188
                     /gene="pgmB"
                     /locus_tag="NOB43_000241"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI0981150.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            58181..59188
                     /locus_tag="NOB43_000242"
     CDS             58181..59188
                     /locus_tag="NOB43_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0981151.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            59210..60229
                     /locus_tag="NOB43_000243"
     CDS             59210..60229
                     /locus_tag="NOB43_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0981152.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(60510..61877)
                     /gene="nhaC"
                     /locus_tag="NOB43_000244"
     CDS             complement(60510..61877)
                     /gene="nhaC"
                     /locus_tag="NOB43_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCI0981153.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(61986..63407)
                     /locus_tag="NOB43_000245"
     CDS             complement(61986..63407)
                     /locus_tag="NOB43_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0981154.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(63650..65527)
                     /gene="tdc"
                     /locus_tag="NOB43_000246"
     CDS             complement(63650..65527)
                     /gene="tdc"
                     /locus_tag="NOB43_000246"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI0981155.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(65818..67074)
                     /locus_tag="NOB43_000247"
     CDS             complement(65818..67074)
                     /locus_tag="NOB43_000247"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCI0981156.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(67186..67391)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            67654..68955
                     /locus_tag="NOB43_000248"
     CDS             67654..68955
                     /locus_tag="NOB43_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI0981157.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(69024..69623)
                     /locus_tag="NOB43_000249"
     CDS             complement(69024..69623)
                     /locus_tag="NOB43_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0981158.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            69877..70758
                     /locus_tag="NOB43_000250"
     CDS             69877..70758
                     /locus_tag="NOB43_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981159.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            70771..72381
                     /locus_tag="NOB43_000251"
     CDS             70771..72381
                     /locus_tag="NOB43_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI0981160.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(72458..73117)
                     /locus_tag="NOB43_000252"
     CDS             complement(72458..73117)
                     /locus_tag="NOB43_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0981161.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(73400..74065)
                     /locus_tag="NOB43_000253"
     CDS             complement(73400..74065)
                     /locus_tag="NOB43_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HCI0981162.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT        22145 a        14963 c        13228 g        23868 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aagaactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttgaat
     1501 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1561 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1621 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1681 attccttctt ctttcttgaa actgaccact tctgtcacac cctctcttct atcactttcc
     1741 ttttttcaca cgactcccgg tttctttgat aaatctcgat actttcaatt ttcttgaatt
     1801 tttcatttga ggtacacata gatacagacg atttcttgct ctagtcatcg caacataaaa
     1861 tagtcttcgt tcttcttcta tcgtcgttac tggttctgct tttatttcat taaagtcgat
     1921 tactttcttt tctgtcgctc cgttataagg caaacttcct tcgttacaac caatcaaaaa
     1981 gacatttcgg taactaagac ctttactttt gtgaatgctc tggatacata gtgcatcaag
     2041 ttttccttgt ctgtaagcaa tcaagcgggt ttttaattct ttagctgtcg cttgggtttc
     2101 ttgcgataag gcttggagtc ttctgaaagt agcatgctgc tttacttctt ctcgtatcca
     2161 ttcttgatca ctctggtcga tttccttagc tatacgtggc agatgaagat agctttgaac
     2221 aagcgaatag atttcttgat gctggtctgt tttacgcaac gcttcctcaa actctcggat
     2281 ttctgcagat ttcgatttta aattggggct tatcgacaaa atataatctg caacggctat
     2341 attttgatat ttaggagaaa agtattgatc gcattcactt tttttcaggt agcagtctgc
     2401 catcagctgc cggagcaatt gctggtaggc ctgatttttc ttttgcagat tcagtgctgt
     2461 ttgccaatga acaatttttt gatagaaatg ttggaaagac ttgataccaa agataccttc
     2521 atatggacta tctgcttcca gtacaaaagg aatattcgtt ttcagcagag attggacaag
     2581 ctgctgcgtt tgtgaagctg atcggtataa tatgattgat tccttatatt tcccattttt
     2641 ttgaataaat gtctgaattt gtttgattag ccactgactt tctgctttag tatcagaaaa
     2701 caaataggct tccataacac ctgcttcttt ttgtgctgga atcatcgcct ttggtatccg
     2761 atcattttta ttatagctga tcaatctatt tgctccttgg acaatagctg cccgagaacg
     2821 ataattagtt aataagaaaa gagttttggt aggatattct ttttcaaagt tcttgatgta
     2881 tgctggctct gatcctctga atccatagat actctgatca tcatctccaa caacaatcaa
     2941 cttgatcctg ttttcctttg tcatccgttt cacgatttcc cattgaagtg gattagtatc
     3001 ttgaaattca tcaatgaata gataatcata tttttggccg atataatgct ggatctcctc
     3061 attctccaaa gcgcttttca gattttggag tacatcattg aactctagca attgctggct
     3121 tcttttttgt tcttggagtt ccgtgagcaa tccatacagt cgttctgata tcggctgtcg
     3181 tgcattctta tcaatggaat catatttttc tttaactaac tgaaccattt cttctactga
     3241 aaggttcata ttctgccaat agtctaaccg agaagcaatc gttttttctc catattgatc
     3301 aaatatataa agattatatt tacgtatcag ctgttgcaaa acagcattca ctttttgtgc
     3361 agtatccttt gaaaagtctc cttgtattcc ttgcattgct acttcaggaa attttcgaca
     3421 aatttcattg tatatcctaa aaaagatact atggaatgtt ccgatatgga cagcggtttt
     3481 tctctggctg aaattatcta ctcgtttttt tagttcattt gcagcgttcc ttgtaaaagt
     3541 gatcattagt atgcgttctt cgtctacttg tttttgcgtc atcagataaa cagcttttgc
     3601 acagattgtt tgcgttttgc cgctcccagc tcctgctatg attcgaagat gtttcttcat
     3661 atcatatgtg atagctgctt tttgttcttg attgaagcga ttataggaac gtttctccat
     3721 cattttaaag aaagagctgt ttccttcact ttcttttact tgtacttctt cctcaataag
     3781 tccgggtgct tcgccataag ccgcttcata ggtagcaatg atttcttctt gtagccgaaa
     3841 gacttgttga agctttttat acttgttctc ccagcgtttc aattcttttt gtaatcggag
     3901 aatttctttt tcattcaact gattgatttc cttcccatct ttcttctttg aatttgttta
     3961 tttcaagttg gttatttaaa gtttcgttgt ctattttttc tttatactaa cagacctttc
     4021 taaaaatgaa aatgggaagc gatatgattt tagttttctg aaaatttttc ctttttttca
     4081 atcgtttatg ctaagataag gaagacaaaa atattcataa aaggtgatga aaaaaatgca
     4141 gacttccttt cacgaggggc gtacaatagg acttttgctg acatttatcg gaggagccat
     4201 ggacagttat acttatatcc aatatggtgc ttttgcctct gctcaaactg gcaatatcat
     4261 tctatcgatc atccaagcat ttgacggaga atggctaagt gttggtaaaa aagtattgtc
     4321 tacccttttc tttttcttag ggattcttct aacaaagtat ctaattgatt attttagaaa
     4381 aaaagaaaaa catttctggc gcttgtttgt tctatattat gaagcagtga tttttttctt
     4441 tgttagtttg acacccgtcc atgagcatcc cgcattagta acgattttga ttgcttttac
     4501 tgcatcgatc cagtgggtag cttttgataa aatcaacggg cgtgcctaca ctaatttatt
     4561 tacaactgga aatttaaaag gggtagcaac gaacttatat gattattgta tttctaaaga
     4621 aaaagcagat tttgatcgat ttttccacta tctaagtgtc gttcttgcct ttatcgcagg
     4681 agctattgtc cttgttttct gtcatcatct gtttggcgcc cattcgattt tgatcgtttc
     4741 cattttattt ttgatcatgg ccctcactca gacatttcat ttatggcaat tttatcatac
     4801 gaatcggttc actatttgat ctcaatgaat caaaaaaact aagcaagatg ctgctcacag
     4861 agaaatatct gcgagtgagc aatttgctta gtttttatat tatttagttg taaagattcc
     4921 ctttgctttc gggttatttg tagtgtagcg gatcgactgg gcatctgcct cttctgtcat
     4981 tttctttgcc cgcatcttga tttcttgtac gatttgttct ccacatgccg gatcggctac
     5041 gaaatcatat ttgtccccat cgatcactat tttgggacat atatcaaact gttcatacca
     5101 ctcttcgtat cgtcgattga gttctttata gtaggaatag agttcaggat cttgttctag
     5161 ctgttcatat tcccggcctc tttttttgat tctcgctaac atagtttcaa aggatacacg
     5221 aatataaacc agtagatctg gtttcttttg tggcgaaatt tcttctaact ccttcagcat
     5281 cgtttctaaa agaccttcat actgctttac ttctacttca gaaacacgcc ctaaatctgc
     5341 attcaaatga aacagcatac tatcttcgta gatggagcgg tctagtacgt tgtcatcatg
     5401 gctgaaagca tctttgattg ccaaaaagcg tttgttcaaa aagaaaatct gtaataaaaa
     5461 agtatacttt tctggattag aataaaatag cggcaatact tcattatctt ccacgttctc
     5521 ataaaaaggt tttgtttcta aatcttgggc aagcatttca gttagtgtgc ttttccctgc
     5581 accgatcgtt cctgcaacaa tgatcacaat tatcggcatc cttcctgtaa taaaatctgt
     5641 tcttcatttt actacttcat ttatagaaat aaaagccttg actttatctg ctccttaaaa
     5701 gctacttctc taaaagtagc caaaagtaac tcctattcat gaaaataaag gctgtgacaa
     5761 aagtcttgtc gcagcccttt tttcaaataa acagtattct cctgccaaca cctcggtcac
     5821 aaggcaatat tcataaaaca tgaaaagctg ttttttaaca ttattccttg taactcagag
     5881 ctaaacggga gactcacaac ctctttatgc tctcaacatt ttatctgttt ttattcttct
     5941 attgtacttg atttgcgtac aactaactgc cagtgcagat tatgagcggt atcattgtct
     6001 tctactgcgc atttcatgac acgtatcatc acactatttt catagatttt ttctattttt
     6061 ccttttattg gtgattcaaa taaatcagat ttaaatgcat atgtttcgcc gacttcaaac
     6121 aattgttcat tttccataag aatccctcca tcacctttta taaggtcagt aattttttaa
     6181 cataaatcac tcgaaaaagc acaaacttgt cataaaaagt acttttcgta tcaaaactgt
     6241 cacttttttt ggtaaggttc ttggaaaacg aagatttttt taggagatca tgacggtttt
     6301 gatgtcaaaa ccacttttta tgaaacaaaa gacgtttttt atttttttta gcataaaatt
     6361 tgtggtggag gtacgtatga gatgaaagat aaagttgtga acaaattatt agaagcctta
     6421 ttcagcggag acaaatcgga agaagatatg gtgtatgtcc aagtaaaatt tgtcttagaa
     6481 gttttattga ataatcttgg aaaactagcg gtcgttctag tcttttctct ggtgacaggc
     6541 tcatgggcgg aaacaggaat cacctttctt tcttatatct gcatccgcag atatgcttat
     6601 ggattgcatt ccgactctga attcgtttgt ctgctgtgga cactacttta tttatggggc
     6661 gttcccttgg tgatgaaaca tctgcaattg actatctcct tcccaatgat ggtctttttg
     6721 ttaatcagct gctttttgtt actgcttcgc tatggatcaa gaggtacagc aatcaatccc
     6781 attgaacccg agaaacgtcc cccattatta aagaaggcga tcagcatgtt tctaattttt
     6841 tctctcatta cgttattttt ctcagcttct tacttttcta cctatttgct acttgggatt
     6901 gttttagaaa tagctacgtt gcttcctatt acaaactact tgatgaattt tggaggaatc
     6961 tttcatgaaa aaaacaatca ttaaacaatt aactaactta tctgactttt ttgtatctgg
     7021 ctgctgcttt ggtatgagtt ctgaattcaa aatccctgaa aaattaaaaa aataatacgc
     7081 caattgtgct ataatttggt aaaaatcaat gggagctgta ctttatgttt ttatggtcca
     7141 tagcgttgca atatttgatt tacacaattt gtatcttatt gattgaccat cacatccgat
     7201 acaaatatct gtttgcggga gtcattctga tttcttgtat tttgattgga tgggtctatt
     7261 cgattttagg gatttttact gctctaattg ctataggaat gctgatgctt acttttttct
     7321 tcttttcgac ttcgcgtcaa caattggttt acgcgcttcc ttttgggtta ttgacgtcgc
     7381 ttttaggaga tcacttaaca agcatcggcg atttttttgt tttgaaatct tcggttattg
     7441 aaccaggaga ttcattgcag tattttcaca ttgtcttatc cgctttttta tctgctttat
     7501 tagctttttg tttaaaaaaa tcgttagaga cttggtttca cactgtggac cgccgtatga
     7561 tcggtacgat cgggacattg atattattta catactatat cattattttt tatacccgtt
     7621 tttctggtga aacacctgat gtcttagctt tgaatacgag ttttttcatt ctatatctgt
     7681 gtgttggcct gatcatcttg gtttattatt ggaaaatctc taataagaaa ttagctgatc
     7741 agttattaga gcaacaagtc aggatgcaac aggattatat caaagatcta gaaaaaaact
     7801 atcaagactt gagagaattc aaacatgatt accaaaatct gcttttttct cttcacagct
     7861 atatttcaga aggcgactta gaaggattac ggtcttatta tgatcaaacg atattaccta
     7921 cacgccagat gatgaacctt tttccggcca atctaagtat gttggataat atgaaagttc
     7981 ctgagatccg tagtttactg tcattaaaac tcatgatggc acaggaaaaa gggttgatcg
     8041 tccagcttca ttttcctgag ccaatcgaac tggatacgaa acatacggta aaccttgtac
     8101 gtatgcttgg tattatcttg gacaatgcga ttgaaggagc tagtgctgca aagaagaaaa
     8161 aaatcgaatt gaccatactc aagaagaatc attccgtgat gattcgtgtg atcaatacaa
     8221 caacaaatac attaccgtta aaccagttga aacaaaaagg gttctcaaca aaaacaaatc
     8281 caaaaaacga aggccttggc ttgtttatct tggatgaatt gacaaagacc aatccttatc
     8341 ttttccttga aacatcaatt gaaaaccagc gtttttctca aacgatttat atacaaataa
     8401 aataaaggag taatgatatg attcccattt atatttgtga agacgatcca aaacaattag
     8461 aagttttatc aacggtgatc aaaaatagaa tcatgattga aaacttagac agttatgtcc
     8521 atatttctac ctctgatccg gaagaacttc tcaatgcagc caagatcaga acttcttctt
     8581 ttggtattta ctttttagat atcgaactag aagacagtga aatggatggt gtagcgatcg
     8641 gtaaattgat ccgtgaatta gatcctttag gaaaaataat ctatgtgact tcccatacgg
     8701 aaatgtcgat gaaaatctta aaaagcaaca tcgaaccgac tgattatatc gtcaaagaag
     8761 atctttatga tttaaaagaa aatgtcgagc atatcctgag caaaattttc gaagattttc
     8821 aaatgtccca aatccaaaaa gatatcttca aaatagagtt taatgatgag atcaaatttt
     8881 taccgatcaa agacatccaa tatttttcta cttcgctagg agcgccacat aaactggaag
     8941 tccatttgac tcatgcccaa ttacaattct atgagaagat caaagaaatc gagaaaatgc
     9001 atcggaattt tatccgttgt cataaatcct atgttatcaa tacacaaaat gtgcggtcga
     9061 ttaataaaaa aaccagagaa gtcacgttgg caaacggcga gaccatccca gcctctatcc
     9121 gtggattaaa gaaattgatt tcataaaaag aaccgaatag tttggaccga ctaaatgacc
     9181 agccgatcca aacccttcgg ttcttttttg cctatcagtg caaaagcatt tcctgtgcaa
     9241 tttcacgtcc atccattgta tctggataaa atgttggcca attctccatt tctttcagca
     9301 atacttcttg actttcattt cctgcatata aatgaaaatg ttcggagtca gccggtgcaa
     9361 tcgtgtgatc actgaattga atatatctaa aagcgccact ttccttatct tctgcttcga
     9421 atagatacct tacgccacgg tttcctgcct cgtaggtcaa gatttctttc cctacataac
     9481 gataatttga acgtttcgtt gttccattct taaacgtaaa tgccatctct ttctcactga
     9541 tcttgattga agcaatatct gtttgatagc ccttcgtata atattcttta tattcttgtg
     9601 ctgtcttatc ctgattcaat ttttctttat attcaaaaac aggatcaaaa gtcccatctt
     9661 ctacatacgt atctactgtt tgccaagttc ctgcccaatc tgaaagagag cgatcttgta
     9721 catcctcgtc ttcaaaataa ccgttgtaga cgctcttttc ttttttgggg gtcaaagtat
     9781 cttctagcgg gttttctgtc tctgtcgttt ttttcaacgc ttcgaggttt gcttccatga
     9841 tagaaagata gttttctcca ttttctattt gttcattcgt caatccttcc aaaggattca
     9901 atacttctaa agatacacct gcttcgtttg ctaacgttct ggcaatacta tctttggcgt
     9961 tttcttcaaa ataaatatag ttgattccat gttctttaac aaagtgtttc agttcagcaa
    10021 ttctcgccgc agacggttct tcactagaag aaagaccagc aatcgatact tgattcaatc
    10081 catattctaa cgctagatag ttgaatgcag catgttgcgt gacaaaagat ctttgttttg
    10141 cttgcttaaa ggtttcttga taaagctgat ggagtgcttg aagtttctcg gtataggctg
    10201 ctgcattttt tgtccatact tcctgttttt ctgggtaagc ttcaatcagc tgatcacgta
    10261 tgtttgctac ctgcttgatt gctaaacttg gagctagcca tacatgtggg tctagctcat
    10321 gtgtatggcc ttcttccccg tgttcatggt catgatcatg tccttcttca cttcccggaa
    10381 gtaaaagcat accttctgtc gcttttatcg tatggacatt gccttcttgt aatgtttttt
    10441 ggattgcggg gacccatgtt tccatgtttt catcattata aacaaagata tctgtatctt
    10501 ggatctttgc catgtcttta gcagaaggtt cataatcgtg ggaatcagtc cctgctggaa
    10561 tcaataactc tacttctcct tcatccccga cgattgcttt tgtaaaatca tacatgggat
    10621 aaaaggtcgt catcacgctc aatttttctt tactgtcctc ggctttccca cttgccccgc
    10681 aagcagttaa catacctgct aaaaccagca tggccaatat acctatcaat cgtttcattt
    10741 atgacactcc tcttctcatc ttctttcatt tgaatgttcc gattcgcttt tcgcaaaccg
    10801 taatagttac gttttagcaa caggatttaa tttatcatat ggttaaaaga actgtcaagc
    10861 gttttcttat tttaattgat gagaaagttt atatgaatga ttgacgatat ttttgcaatc
    10921 aacctctatc attttccttt tatacccgct tttgtctata atgaagttat agataaagga
    10981 ggaaaaagag tgaaaaaaga aacagataca acgaatcgtt tgatccgctt tttaggagga
    11041 aaaacctctt actatgtttt aggaatagtt atcttacttg cgctgatcat ttattttttc
    11101 catcagatct cgtttatatt caagcctgtc ggaatcatta tcgctactat cttgccccca
    11161 ttattgtttg cactgatctt gtattatctt ttggaaccag tcatcaaacg tttgagcaag
    11221 cacctttcga ggaacttgtc agtcattatc gtttatgtga ttattttatt tttattgggg
    11281 cttggaagca tatggcttat tccttttctt gaagaacagg caaagacatt gatcagtagt
    11341 ttgccagatt tgtttcaaga ttttcaagag agtctccgac aatttttgga gaaaacacct
    11401 tttgccgatt catttaatca atttttcgct tctattgacg acgtgacgtc tgatatagct
    11461 ggatttattg gaaattattg ggaaagtggc gcacaacgga tcagcaacat tttttcaact
    11521 gttacagcta tttttattac tttatttact ggtccaattg tcgctttttt ccttttgaga
    11581 gatcctcaaa aattttatca gtcagtttta gcgattgtcc caccagcatt tcgtacagat
    11641 tttaaaaatt tgacaaagat tgctaatcaa caattgggtt catttctaaa ggggcaaatc
    11701 attgcttcat ttatccttgg agcagtctac tgggtttgtt tcttactgat cggattagaa
    11761 tttgctagtg ttttagctat ttctgctggg ttgttatgta tcattccata tattgggccg
    11821 tttatcgcct tctttccagg tttgatcatt gcattccaag actctacttt tatggctgtc
    11881 aaatttgtca ttgtctggtt tgccgtacaa cttctccacg gtgacttggt gattcctcga
    11941 gtaatgggtg atcgtttaca gatccatccg attacgatct taatcgtttt acttgtcatg
    12001 ggtgatctaa tgggaattgt gggcgttatt tttggtattc ctatctatac gttagtcaaa
    12061 ttactcgtta cttttatttt ccgtaaattc aaacaacgct acaataaatt ttatggcgat
    12121 aaaggagagt atgaaaactc ttcattttct gaagaagatt attttaaata aaacacaaaa
    12181 cgtcgatctt acgagaatag ctcgtaggaa cgacgttttg tgtttttgtt ttaatttttc
    12241 agcaaagcaa ttgcctggta tggttttagc tccagacttt gatgaagaac agtatcggaa
    12301 taattatcga taagaatatt ggcttctgtg aatccttctg ggatggcgat ccttgtatct
    12361 ttatcataga aatttgttaa tacaagcagc tgctgtcctt caaattggcg aagaaagcca
    12421 taaacttccg gatgatttgc ttcataagca tgataatctc cttgtgcaac gattggatat
    12481 gtttttctca gccgaatcaa tttcttgtaa taggacaaaa tagaatcttc agaagatagt
    12541 tctttttcta cattaatctc ttctagcttg cctccaactt ttaaccaagg tttccctgta
    12601 gtaaatcctg cttgttctgt gtctgaccat tgcatgggtg ttcgagagtt atcgcgagat
    12661 tttgctttga tccgacgaaa cgcttctttt tctgtgaatc cttgttcaag gagtaactta
    12721 taagcattca aactttctac gtcaatatag tcggaaatcg atgaatagtc tgggtcgatc
    12781 atgccgattt cttctcccat ataaatatag ggcgtcccac ggttcaaatg gatcatggtt
    12841 gctagcatct ctgctccttg ttttcgatac tgatcgatag ctacaaatcg attgagcgca
    12901 cgtggctgat catgattatt aaaaaataga gcattccagc cgttaccctc actcatcttt
    12961 tctccccatg tatgaaatag tcgctttaat tctgcaaaat caaatggagg agtagaccat
    13021 ttattcccat tttcataatc gactttcaaa tgatggaaat taaagaccat tgataattct
    13081 tctctactag gttctgtata caagatacaa ttttcgatcg tcgtagagct catttcaccg
    13141 actgtgatga tagtggaatc cgtcccaaac gttgcttggt tcaattcttt tagatacgta
    13201 tgggtgattg gtttgtccgt atattcaggt ttgccatcat tttctttatt atttttcaat
    13261 tgttcgtctt taccgataac attgataaca tcgaaacgga atccttttac ccctttttcc
    13321 atccaaaaac gaacaacttt gaatagttcc tctcttactg cttggttccg ccagttcaag
    13381 tcagcttgtg tccgatcata taagtgcaaa taatatttcc ccgtatctcc aaatggcgac
    13441 caagcacttc caccaaattt tgatacccaa tccgttggct cttctcttaa aatgaagaag
    13501 tcctgataat gctggtcccc tgctagtgct tttttgaacc attcatgttc tgtcgaaacg
    13561 tgattcagca ccatatcgag catgatttct atccggtatt tctttgcttc ggctattagc
    13621 tgttcgaatt cctccatcgt accaaagata ggatcgatgg ctgtgtaatc agagatatca
    13681 taaccgttgt ctttttgagg gcttggataa atagggttta gccaaatcat gtcgatgcct
    13741 agatcattca gatacgggag tttttctttg attcctttta aatctccaat tccatcacca
    13801 ttactgtctt tgtaagattt gggatagatt tggtaaatga ctttgtcttt aaatgtcatg
    13861 gatatttacc tccattcaac tgatttatta cctaccacaa cttatatata caagttatca
    13921 tttattatta taactgaacc gaaagcgttt gtaaaattta tctttataca ttctaagagg
    13981 tctgttgccc aataaaaaac aagagatcag acatgtattt gtctatcctc ttgtttaaaa
    14041 tagcaaaata ttcttgtttc ttctataaat ggtgttcaaa agcttttatc tacggcaatc
    14101 agtcttctca aatgtaaaac atgaggagct aattttattt gagtattctt tttgctcgat
    14161 gcaggacggc ttttttacaa cctctgattc atggtgttca atcagctgtc cttcggtatt
    14221 agctcaaaaa acggcaaaat atgaaaaact attttgccgt ttgtttctct aatactcagg
    14281 tcaaaccgct gatttcacaa cctctgtttt tattcattcg atttcaacgc atcaatcata
    14341 tcgatatgct ttaatttgaa atgggtaaca atcatcacaa taaccgtaaa tacgatagtt
    14401 aatcctgctg ataagacata agcccaccat gtgatcacta atggaaagat gacattctcc
    14461 atagacgctt gttgcaagat gaagtcagtc aatatatatc ctacaccaaa tcctccgatg
    14521 attcctaaaa gagtaaagat gatattttct cgaacaatgt acatcgtgac ttctttatca
    14581 aaaaatccaa ggacttttat tgtagataat tcgcgtacac gctcggaaat attgatatta
    14641 gttagattat acaagacgat aaaagccagc agtcctgata atacgacaaa gattaagaca
    14701 accgagtcta agttcgccat tgattcttct tgcgtttcga tttgtttgga catgaaagac
    14761 gtatttgtca cagcgtctgt ggcaagcagt ttctcggaaa gcatttcttc ttcttttgtt
    14821 gtcatcttat ctgtacgcag caaaaatgca ttatccatca tcgattgatc agtaactgaa
    14881 gcataatatt caggggacat ataaataaag ctacctagat agtttttcac gatttctttt
    14941 acttcgactt tccattcttt ttgatcttca tcataaagcg aaatatgatc tcctgtagat
    15001 aagtcaaata gttctgctac tttttgcgta atagcgattc ctgttttagg caaggagcgt
    15061 gggttctctt caagatcagt taaatggata aaacgatcca aatcagctgt tttacttggt
    15121 acgatcactg tcagactttg cgaagcatgt cctttttttc tcaattctac ggtttgagta
    15181 tgaatagcta ggatctcatt tactttttct tgcttctgca gcatatccgc tgctttttga
    15241 cgactatctt ccgtggatga atccaatgta acgattgctt gatagtcaat gatcggtcca
    15301 aattgtttgg ctgaaacaga acttagagaa tctttcaatc ccacgcctgc aaccatcagc
    15361 ccggcacatc cagcaattcc gataatcgcc ataagcattc ttgacttata tcggaagaga
    15421 tttcggtaac tgattttttg attaaagcta aggcgtgacc acagcggagt gatgtattca
    15481 agaaaaatgc gtttccctgg cttcggtgct ttcggttgaa gcaatgcagc aggccgttct
    15541 cttaaatctt tgaataaaac gatcattgca gcgccaaatg cggcaatgaa gaatgcggca
    15601 gctgcttgta aaatcggcgg ccagtcataa aaaataagcg cactcccaat atcataccgc
    15661 tcgttagaca gctcaaaaat gatccttggc aaaagattcg ttcctaatat cgttcctaaa
    15721 acaataccta tccctgaggc tagacttgca tagattgcat atttttttgc gatttcaact
    15781 ttcgtataac ctaacgcctt taatgtcccg atttccctgc ggttttcttc taccatacgt
    15841 gtcattgtcg taaaggtgat caatgcggca ataaagaaaa agaaaacagg aaaaacattg
    15901 gcaatcgcag cgatacgatc agacagatca ccaaattctt gaaaaccgac attttctgaa
    15961 cgttcattgt ataggtatga tggtttagtt aaattttcaa ttttttctgc atttcgattc
    16021 aattcttcct ctgcagaggc cagttcacgt tctttctcaa ctaattgcct ttcttgttca
    16081 gcaagttgag cttcttgttg agataatgtt tgaacagcga ttgttcgttg cgcttcagga
    16141 agctgctgga tagttgctga ctgttgcgct aactgttttt tagcatcttc taaccgtgtt
    16201 cttgcttgcg ttgtttgtgc tttgccatcc gctatttttt gctgtgccgg ttctaattct
    16261 tcgttggccg attttttcag ctcttctaag cgttcttcgg gtcgatcttg taaatacttt
    16321 tctgcctttt cttgattttg ctccatttta tctttgtaag ctttgctgta cgtattcaaa
    16381 ttctttacgt ttgtaaaatc aagatataag acagaataaa tatctgtttt aaaaacggat
    16441 tcaggtaaat agacaaaata atcgacgcta ccatttccga cgttcgcgta tcctctctcc
    16501 aaattgttga tgaacaatgg agaacggaca aagcccgtga tggtatactc tttttctttc
    16561 aattcatctg aatcaatctg ataaatatca ccgattttat acccttcatc ttccgctttt
    16621 tcatccaata caagctggtt tggtttttcc gggagttttc catcagttaa ttgtagcttg
    16681 ttctgcttgt tatttttgtt ataagaaaat atttgaatca cttcgttttt gccagtattg
    16741 gaataataga tctgttttcc tgtttctact tttgcatctg ggatcttttc tgcttgagca
    16801 atatcttttt gtgtcaagcc accagtagaa acgatttgca aatcagaaag tcctgctgta
    16861 ccaacatagt gatccatcgt tttttgcatg acaggtccag cagttttgac acctacaaat
    16921 aaaagtgttc ctagcatgac aataaggatg attgcaatga atcgtccttt agattgccga
    16981 atttcgcgaa aacctgcttt aagatatgtt cttgttttca taaaatcccc ctaccataca
    17041 atctcatcaa tggatgaagg atgatcattt aattcaacag accttacttt agcatcatta
    17101 atgtgaatga ctctatcagc gatgggcgct aaagcagaat tatgtgtaat gatcaaaacg
    17161 gtattgccgt gttgtctgct agcgttttgc aataatttca atacttgctt gcccgtttca
    17221 aaatccagcg cgcctgtcgg ttcatcacat aaaagaagtt tgggattttt agctagtgca
    17281 cgagcaattg aaaccctctg ctgttcgcct cctgataatt gggacggaaa gttattcaat
    17341 cgatgagcta ggcccacttg cctcaatacc tctacaggat caagcgcatc aggagaaact
    17401 tccgttgcca attccacatt ttcttttgct gttagattag gaacgagatt gtagaattgg
    17461 aaaacgaacc ctacatctgt tcgtcggtaa gcagtaagct gtttatctga aaattgcgca
    17521 atatctgtgt catcaataat gatctgacct tcatcaggtg tatccatccc acctaaaata
    17581 ttaagaatcg ttgactttcc tgctccactt ggaccaagta taatcactaa ttcgcctttt
    17641 tcaattgaaa aagaaatatc gtcatttgct gtaatggtcg tttctcccat tttgtatcgt
    17701 ttgtattcat tttttacttc gacatacttc actctgattc ctccattttc acgatatttc
    17761 tcgctatatc tatgcatcga atgcgttttc tcacacttat ttattttacc actgaatttc
    17821 tctagactaa agaaaggaat cctttaattt agttgacaaa taaacgattt atgatttact
    17881 tacataaaaa acattgttat ttgaaagaag gaacatcatg aatgatttaa aggaaaatat
    17941 gatttttgat ttatcaaaaa ctgcttttgt cgcgatcgac atgcaaaaag agatcgtaaa
    18001 taacggtaca ctctctccac acactgcagc atctattctg acaaacaatg atttgttagt
    18061 aagaacattg aaacgtaccg ctgccttgaa agttttagtg aacgtagaca tctccacttt
    18121 cccttatttg agtcaacaaa ctgatatggg tggaatgact gcttctgtac ctccagaatt
    18181 cactgattta cttttgaagg attctttgaa agatacagat aatatgttga ctatcacaaa
    18241 atacaatcca agtgcttttt ttggtacttc tcttgatctt caacttcgcc ggcgtggaat
    18301 cgaaactatc attttaagcg gtgtagcgac aacaaacggt gtatatgcta ctgcattaga
    18361 tgcctttcaa cacgggtacc atatcgtgct tgctgaagat gcttgcagtg atcgtgacaa
    18421 agaatcccat caattgttca taaaaaagat atttccgaaa actgcacgag tacgctcaac
    18481 gaaacaaata atcgaagcta tccaacaaag caaataagta ctggcacacg tgattttcat
    18541 ttacttcttt ttgatttcat gggaaaataa ccacaggatt tagataggag tatgaacatg
    18601 gtgaaaaaaa agatcacaat caaagaagtc gctaaacttt ccggcgtttc aatcacaact
    18661 gtctccttga tattaaatgg aaatacggag aaattcagtc cgaaaactgt tcagaaagtt
    18721 ttagctgcca aagaagaatt aggctatcag cctgactatt ttgctagaca aatgattacc
    18781 aaggaaacga aaacaattgg tgtactcgtt cctgatatca cgaatccatt cttcagtaca
    18841 ctgatgcgag gaattgagga tatcttgtat aagcagaatt tcgtcacgat attatgtaat
    18901 gctgattctg atcatcaaaa agaaatcgaa tatctagccg agctcacacg tcgaggtgtg
    18961 gatggattca ttatcgcgac ttctgctgtc tctacagatg caatcaacga aaatttgaaa
    19021 aaacaaggcc ggcccttcat tgttttggat cagaaaaaat ctgaaggatt tagtgatgcc
    19081 gtacgaacag acgattttcg cggtggttac ctagcgggca tgcacttgct tagtctagga
    19141 catcaaacga tcgcccttgt ctatcctgaa aatccaccgg aaaatgtcca cgctcggatt
    19201 gaggggttta aatctgctct tgatgtttac caaatccctc acgaccaact gatcctctta
    19261 cctacacagt tctcaaaaca aggtggctac cagatcacag cagaacttct tgattctgct
    19321 gcaactggtg tgtttgcttt aaatgatgaa ttagcttttg gattatatcg cggattagag
    19381 gaagctggaa aaagcatccc tgaagactac agcattattg gctatgataa tatagatatg
    19441 tgcgagtata tcaagccgaa actgacaacg atcgcacaac caatcttcga attgggacaa
    19501 acatctgcca agttattgtt agatcggatc caattcccag aaaaagaatg ggaagaaaaa
    19561 agattacctg tacgattaga aaaaagattt tcaactgcac ccttgaaata gctttcaagg
    19621 tgtgctatat ttttatcgaa ctattaaaac gttttactaa aacgttttaa aaaataattt
    19681 tcccatcaaa ataaatgaga tagttggagg tttgtaaaat gaacacggtt acagtaattg
    19741 gaagtattaa tatggacact acccttcgtt taaccaacat gcccaagcca ggcgaaacga
    19801 tgcatgcgca tgagattttt cacgctggcg gaggtaaagg tgccaaccaa gcagtggcag
    19861 ccaaacgttc aggcgcacgg acatctttta ttggaggcgt tggggctgac agcgaaggac
    19921 aacagttatt agatctactg acaaaagaaa acatcgatac atctgggata gctgaaatcc
    19981 aaggcgccac aaccggacaa gcaatgatta tggtagacgc agcaggagaa aatagtatct
    20041 tgatccatgc aggggcaaat aatgctttcc atgaacaaga agtcctaaaa aacaagcaac
    20101 tgattacaaa cagtgacttt attattgctc agtttgaaag tagcttagat gcgacgatcc
    20161 tagctttttc tattgcaaaa gacgcaggaa aaacaacgat cctgaatcct gcaccagctc
    20221 gtgaaacgat tcctactgaa ctacttgaaa agacagatat cattatacca aatgaaacag
    20281 aaacagaaat cattacagga atcagagtga cagatcataa cagtttggtc gcagcagccg
    20341 aaaaactcca tgaattaggt attggaacag taatcattac actaggcagt gccggcgctt
    20401 tctatcatac agaaaaagaa cacggtatcg tccctgcttt taaagtggat gcccttgaca
    20461 caacagccgc aggtgataca tttattggcg cattaagcag cacacttcag ccagacctta
    20521 gtaacttgaa agaagcgatc ctttatggaa atctagcctc ttctgttgct gtgcagtctt
    20581 atggtgcgca accttctatc ccttaccgcg aagctttaga acaatcagca gtctaaaatt
    20641 aacaatgaga ggaagaaaca aacatgaaaa aaggaaaagt aatcaattca gatatttcac
    20701 gagtaatcgc acaaatgggg cactttgata aattaagtat cggggatgca ggcatgcctg
    20761 tcccctttgg tactgaaaaa atagatttgg ctgtctcaaa cggtcttcca agttttttat
    20821 ctgttttaga aaacgtttta gaagaacttg aggtacaatc gattgaattg gcggaagaaa
    20881 taaagacaat gaacccggaa atattggaaa aaatcaaatt attgttacca gatacaccga
    20941 ttagctttat cccacatgaa gaaatgaaaa aagagttgaa taactgtcat gcatttattc
    21001 gtacaggcga aatgacacct tacgccaata ttatattagt gagtggagtg gtcttctaat
    21061 ggaaacgaca atgaatcctg aacagatggt actgtccgag cagattcata tgctgattga
    21121 acagttggga ggaaaagaca atattgattc tgtccttcca tgtgcgactc ggcttcgtat
    21181 caaattgaaa aaacagccag tagccaatgc agaaaaatta aaacagcaaa tcccttccat
    21241 taagtatttc attttactcg atagatatgc agaaataatc atggatcagg gattggctcc
    21301 tgcttacaag gaattgacgc gtcaaatcga tcattcagct ccgaaagaaa agctaaatcc
    21361 gatcgaaaaa ctatttggtt tgatatcgga aatctttacg ccgatcattc cgctgtttgc
    21421 cggttctggt atattaaaag gtctggttgt tttagcgact acgattggct ggcttagtga
    21481 aacaagcgga acttatcata ttttgtctgc tgcgtcgaat gccgtctttt attttctgcc
    21541 aatctttctt gctttttctg ctgccaaaac gtttaaagtg aatggatata ttgcggctgt
    21601 cattgctgca gcactgattg aaccgaatct gacctcttta ctttcagaca gtggcaaagc
    21661 agctactgat tttctgggga ttcctgtagt actgatgcag tatacgtcta ctgtcatgcc
    21721 ggcgatttta ggtattttct tttattcttt tgttgaaaaa ttcctcaaaa aatatattcg
    21781 cgaaaatatg caattagtat ttgtaccttt actttcatta gttatcacgg ttcctttgac
    21841 gttaatggta ttcgggcctg cgggtgttta ccttggcgaa ggtttagctg ccgcaattac
    21901 ttggatgatg gatattaacg gaccgatcag tggcgcaatc atcgctggtg gttggaatat
    21961 tttggtaata tttggtatcc aatgggctgt aaaccctgtc atgatcagta atatctctgc
    22021 ttatgggttc gaccgaatcg ttccgttgac aggagcagcc aattttggaa tggctggtgc
    22081 agctttaggt gtatttctgc gaagtaaacg ttcaaaaacc cgttcgatct ccggttctgc
    22141 ttttgcttcg attttacttg cgggagtgac cgaaccaact gtttacggaa ttgcgatccc
    22201 attgaaaaaa ccatttgttg ctgcttgcat tggtgcagct gctggtggag ctgtaatggg
    22261 atttgcccaa gtgaaagcga tcgcttttgt atttggtagt ctgaccacat tgcctgcatt
    22321 catttccggt acttttttct ggtacttagc aggactggct gttagtctag tcgtagcaat
    22381 gatcactact ctcgttagcg ggtttgatga agacctaatg tcttatgaat agttaatgaa
    22441 aaagactgaa gtatgagatg tttatcacat atttcagtct ttttcttttt aggatcatta
    22501 tttttataaa tttttgtgat actttccaaa ctttggtata atttacatat gcataaccat
    22561 ttttatcccc acttgtttat ccccaaacaa aggtggtcta tgcaataaaa tgaacgtcaa
    22621 agaaaaacga atgaatgctc gttgcttatt tacaaattgt tttatttaga atacacagac
    22681 agatttatga aaagaaaaag cttttcgaca cgattatctg ttccaaaaaa tgtctaatga
    22741 atgctgaata agacagaaaa tcaatgaaag gaaaaggact agtttattat gaaaaataaa
    22801 aaaacgatac gtttgctagc tgctacttgg ctgattgctc cgtctgtttt gtcgaccaat
    22861 accgtatttg ccgtagataa tcaaatagct gatcaaacag tcacaacaga tacgactaca
    22921 tccagctcag ctactagtga aacaacggat tcttttacag aagacccaac tggaacaact
    22981 aactcaacaa caggatcgac cgagccaact gaaattgatc cggctgatcc atcagaaaat
    23041 gaaaagccag ccgagacata ttcccttaca attgctcctt ctttgattgg taagatccaa
    23101 ctgactgctt cgacagcgga ttcccctgaa cagcaacctt tggatattac ggaaagtgga
    23161 acggtagaag gtttattagc ggaaacgaag gtaacttaca ctattacgcc agctgaaggt
    23221 gaacaaattg cttcagtcgc tgttaatggt gccaaagaag taaattatga tgcaaagacc
    23281 tttacagtag gtacgaacaa tttatctatt actgcagaat ttaaagctgg accggatact
    23341 tcaacagaga aaccaactga tcctagtgaa gaagtcccta gtacaccaga tccggaaacg
    23401 ccaaacaaac cagatgtggg taataacaac aataataatg gttcaaataa ttcaaacaat
    23461 aataacaata attcgaacag cgggaattct tcgaatcaaa caaacccatc tggatcgaat
    23521 aacaatggaa atactcagag agaaccaaac catccaaaca atggttcatc gaatggcgga
    23581 acgaacaatg cttcatctcg tccaaataca gcaaatcaaa gcggtataga gaatccatct
    23641 tctgcttctt ctgattttgt tgtaaaatca ccaattgatg ctgtattgcc tacaaataca
    23701 acgaatgtcc aacaagcaat cgttcgagaa gcattcaagc atcttggaaa accatatgta
    23761 tggggagcaa aaggtccaaa tacttttgac tgttctggtt tgacttatta cgtatatatg
    23821 aaagcaaccg gtcattatat cggtggctgg acaggcgaac agcaatatgc aggtacgcag
    23881 attccagtaa gtcaggccca acctggcgac ctcgtcttct ggggaccttc ttccggtgtt
    23941 actcaccatg taggtatcta tattgggaac ggacaattta tccatgcgcc tcaaccagga
    24001 gataaagttc gagtaacttc tatttcagat ttcacgcctg attttgctgt ccgagtaaac
    24061 ttagcaggtt tacctgctgc ttcaggttcg ctgacaggcg gctcatctat tttagatgga
    24121 ttagatggct cgttccattt cagtcaaaac caaacaactg atcagttctt gaaaaagatt
    24181 gcagatgatg cacaggaaat cgggcaaaaa gaaggaatct acgcatcagt catgatggct
    24241 caagctatcc ttgaaagtgg atctggaaac agcttattat caagcgaacc aaatcataac
    24301 ctttttggta tcaaaggatc atataaagga agcagcgtga ccttcaatac acttgaacaa
    24361 gatagttccg gacaaagcta ccaaatccgc gcacaattcc gtaaatatcc ttcttacaag
    24421 gaaagtttgg aagactatgc cgacttgatc aaaaatggac tgactggcaa tcctgatttc
    24481 tacaaaccaa cttggaagtc ggaaacaaaa gactacaaag aagcaaccaa atatttggaa
    24541 ggacgttatg ctacagatcg ccaatattca caaaaattga acgcgatcat cgaagcgtac
    24601 gacctgacaa aatatgatga accgaaaaaa gaagcagcaa caactgaaga agcaaacgct
    24661 gaaatcctca atatgtctaa gcgattcgat gtgccaatca aatggacaac agatggcgtg
    24721 ccaatcacag gattagaatt ttcaacgata aaacgcgtca acaacgcttc ttccatcttc
    24781 cgtgtcgctt caatctggga tttgtggaac aattttacgg caagacagat accagaaaca
    24841 actactcgta cagttaaagc tgcaactgtt cctgtactaa ccttgttaag tttagacaaa
    24901 tcattctggc ttgatctgcc tttaaagaaa tagaataaat taaaaagggg atgtgacact
    24961 gtcacactcc ctttttaatt tattctattt ctttatattt attttgtatt ccgttacaaa
    25021 ctcgcgtact tggttaggtt ccagagtgac atctccaaaa ctttcaagtc gctccgctcc
    25081 tggcagttct tgagtctcaa atgtgatacc gccatgattt actaatttat tcccgcgcat
    25141 ttccggtcca tcttctccaa aatttgctgt aaaaatcacg attcctgaag catctgtttt
    25201 tacttggatc gatacttttt catctgggct tgtcaattcc gcagcattta gtaaaccaga
    25261 ttgttttttc aacaaaaatg gatgatcgat gccgcccact atcattgatt ggcgaaaatc
    25321 actggcaaag acctcaccta attttttagg acgttggaag tcaaatgctg tgccacttac
    25381 tgaaactact tctcctgtag gcgttgtatc tttattgagc gtagcaaata atcggctatt
    25441 caaccaaagt atatgttcgt cgattgactg tgctggatca ccggttaaat tgaaatagac
    25501 atgatttgta ggattgaata ctgttttgcg gtcactgatc ccttggaccg tcactcgcca
    25561 tgtatcatcg ttcgtcagcg tataccgtac ttctacatct aaagttccag gaaatccgtt
    25621 ttccatatct gggctagtct gatagaaaat gaccgatgct tcgttttcac cattgatgac
    25681 tgtataatgc cactgcttgg cttcaaagct aggtgcacca ccatgtaaac aatgaccagt
    25741 gtccgggtct gtttttactt cgaacgtttc atcatctaat ttgaatgtgc cattcgtaat
    25801 ccgtccagcc atacgtccga ttgaagcacc gatataaggg tctttttcta gatattcttt
    25861 tgcttcatca aaacctaaga tcaactctcg tttttcatta tcgattattg tttgaaaatg
    25921 aacaacccgt gccccaagat cactgacaga caaagatgtc ccattttgat tcgtgatcgt
    25981 aatcaagtga tagttttcgc caaaattttg ttcattgatt tccatgttcc ttgcaccctc
    26041 ttttctttca tttgcactga ttccagtata catggaaacc gttttcttaa cagcttattc
    26101 cgtgagtaac gagaaaaaat ttactatatt ctaataaaag accgtgaaaa aaaggttgtg
    26161 acaaaaatat tgtcacaacc tctttttccg aacaaacggt gttcaaaagc ttgcatctgc
    26221 ggtaataagc ccaaccaaac gaaaaatatg aggagctatt tttgcttggc tgttcttatt
    26281 acttgatgca ggacagcttt ttcacaatct ctttttcaat acgattccag tatataacca
    26341 tgtcgtcagt acatagtaga tgaaatacaa tacgaagaat atcgtaaacg gaacccaaat
    26401 atctttgtat ggattttgca tgaatagacc aaacatttgt aatccgaata agacatggac
    26461 tacacctaag attcctggtg ctaagaataa cacgcctact tctctacgga tcgattgttt
    26521 aagcaacccg cgtcgtgttc ctatcttttc aagcatttca taacgagcaa tgtcactctt
    26581 gcttcctgac aagatcttga acatcaaaca gctagcaagc atggtcaaga aagctaaacc
    26641 taggaagaat cccataaatt caaaaccaga gaatagacca ttatacactt catacatttc
    26701 atatttctgg ttgctgtact ctactttttg caaagatgga ttgttcattt tattttgagc
    26761 aacaagtgtt tcgattggtt tcaggtttgc ttggaagtct tttacctgaa ctagctgtaa
    26821 agtggattgt ggcaagttca gttgatcaaa ttctgattga ctgactacct tgatttcttt
    26881 ttcttgctgt tccggcaatt catagcttcg aagttcctct tgtacagtca gttcattcat
    26941 ttttttagca ggaacttttt ctttcgtgat cttcggcggt gttccatctt catgttttat
    27001 catgatcaat ggttgagccg caaattcact tgcattatag taaatcgttc ccgcatcttc
    27061 tttttgagta taagaagcag aaagtgttgg tgaaagttct ttgatttttt gctgatcttc
    27121 tgcccgagga ttattcatca ctagatcata tccagaattg ttttctgtca agtctgcaat
    27181 ttcattttta aaacctaatc ctaccgtcaa agcgcccagt gccaaggcaa acagcatagc
    27241 gaccattgag agcatttgtg tatattcacg aatacgaaag tttaactgtg acaatgtgaa
    27301 attgttcaat tttttcaatg aaatctgttc tgatttcttt agtaatgata aaaagaaaat
    27361 gatcacagaa tggaaaatga aataagttcc taatacgatc gtaactaagg ctacccctat
    27421 accaaagact tgataggtcc ccacgtgttt catcatatag taaccgcagc ctagaaaagc
    27481 aattcccagt actacttcaa ggaaaaacaa gaatttatgc tgcttgattc ttgttggtgt
    27541 ctgatccgca cgaatcaatg ctaaaatcgg ttttttgaca atcgaaaaag cattgacaac
    27601 agcagctaat aaaaacaaaa cagcaaaaaa caaaacagtg atcaacaacc cgtgaatact
    27661 aaaaggtgta aaatgcgaaa tattgagatc taactgatcc actaataatc ggtggacgat
    27721 acttgtcaat cctacaccga cagctgaacc cactaaagta gctgcgatcc ctactaagaa
    27781 tgtttcagaa aaaatcatct gtgcgatttt tctgcctttt gctcccagca tcataaacat
    27841 tgcatagtct ttttgccgca tcgtcatcaa aaaggaattt gcatataaaa tataaacgaa
    27901 tgtgatgatc cctagtaaaa cagaaccgaa tcggaaaatg ataactgtag ccgcaacgat
    27961 cgtattactt ttcaaaaaag cttcgttgct tgccattgat tcaaacatgt aaaaaatagc
    28021 agatgccata actaatcctg agaataacac caagtagtct cttaaacggc tcttgatccc
    28081 agtaagtgat aatttccaaa gcatagtcaa tctcccccta ctgttccaag tttccaagaa
    28141 tagatagtat ttctcgatag aaggaatcac ggctttgatc tccacgtttc acttcttgat
    28201 ggataccgcc atccttgatg aataaaatac gttggcaata acttgcagaa aacggatcat
    28261 gcgtcacaag aagaatcgat acatgatctt ttgtattcaa ttcgtccatc gtatctaaaa
    28321 gatcccgggc acttttggaa tccagcgcac ctgtaggctc atcccctaat agaatcgttg
    28381 gttgtgtgat caatgcacgt gcggcggcga cccgttgttt ttgtccaccg gaaatctcag
    28441 aaggatagct ttccaaaata tgagagatgg ataaacgttc tgcaattttt tggacacgtt
    28501 gcttgatttc ttttggtctg acgccttgta aagaaagagg aacagcgata ttttcttgtg
    28561 ctgtcaagct ttctaataaa ttgaaatctt ggaaaataaa gccaatctca ttcgcacgaa
    28621 aatctgctag ttgatttcct tttaatgtgg tcacatcttt ttgattgatt cggatatgcc
    28681 catctgttgg tttatctaat gtggataaaa tattcaaaag tgtcgactta ccagaaccag
    28741 aagcgcccat gatcccaata aattcgcctt tttctacatc gaagctgatg ccgcttaatg
    28801 cttgcgtctt tttctcattg ttttttccgt atacttttgt tacattctgt acttcgacta
    28861 ttttgttcat ttctttccct accctttaat tagtttttcc agtgctgttt tcggcacgtc
    28921 ttttttttcg acttcttcat acgaagtgac acctttattt ttgttccagg tgatttttaa
    28981 atatgctcct ttacgaagcg gtcgagtcaa ttgtcccttg aagtccagtt ctttttcctt
    29041 accctctttc gtatagccag gcaggatata tctatagttg actgtttctt gtccagagtc
    29101 tgattttgaa actgtttttg taccatctgt cgtaatttgt acatagtatt cttctccacc
    29161 cataactacg taatctgcga ttttcacccc tgcaagtacc acaacgatga aaacaagtag
    29221 accgatcaga agttttttca ctttttcccc ttctctctta ctttatatac tgattataga
    29281 aaaaagcgaa caattctgcc ttcgaatcaa ctatcattct tctttcaatt ttgtcatttt
    29341 ctttaaaaca actaaaaaaa gagttcaaga caataatccg tcctaaactc cttcttccta
    29401 tcttacaaaa agtatgtcac ttacggtctt tcatgtcgcc tgtattgata acaggttgcg
    29461 ttcctttgtc tgtaatgatt gagacaagta aattattgat caattggact ttccgatcat
    29521 cggtgaaatt gatttcttgt ccatcttcga tttgctctaa ggccatttga gtgattgtga
    29581 cagctccttc aacaatggtt tgtcgagcag acaaaatggc ttttgcttgt tgacgttgga
    29641 gcatggcact agcgatttct gttgcatagg ctaaatggtt caagcgtgtt tcgattactt
    29701 cgacacctgc tactgctaaa cgctcttgca gctctttttg caactcgtca gacactgccg
    29761 tcgtgtttcc tcgaagcgtc aaatcattct cattgaatgt atcatacggg tattggctag
    29821 cgatatgccg aatggctgtc tcactttgga tttctacaaa atcttgataa tacgctacat
    29881 cgaataatgc ctttgctgta tcaacgactt taaagactac tactgctgag atttcgatgg
    29941 ggtttccatc caaatcattg acttttaaaa cagaactatt gaaattccga actttcaacg
    30001 aaacagtcat tttttgtgcc aaaggtatcg taaggaaaaa gccattttct cgaatcgtac
    30061 ctaaatattg tccaaaaaac aaaattactt ttgcttgatt aggactgact acagttgccg
    30121 aacttaacaa caataacgtg atcaaccaaa gaaaaatact taaaaaaagt gcccaaactt
    30181 tcgcttgcca catacctaaa tagaagaaaa acaatccaac taaagctaat acgaccaatc
    30241 cgacaatccc tgcataacca ttgatataaa atgctctttt ttctctcatg ctacttcctg
    30301 cgctccttta tccttcaata aatatctaat gttacttttt taattttttt ttcgaatacg
    30361 cgccattaca ccttctagtt ctaactcttt gtcttcagtg atgtaccaac cgcttgcctg
    30421 tgtccctccg gctgcctgcg gtaaataatc caattttgtt cgaacccagt gcttttcttc
    30481 tgtaaaatag tcttctacca agacctctag atccatccct gctgaaagag gcaaatcttc
    30541 ccgaacagat ttaaagataa atcgttcctt cttcccatca tacttcaata ttcctgtatc
    30601 gataatcggt aaagaataat aatccagctc tttcttcacc gtcaataaat gtttgaaaac
    30661 ttcatggtac acttgctcta attggcgacc ttctgaattg ttcgggtaat taaccatcac
    30721 tttttctttg tctggatcat agaaggtttg gcttagttga gtgatataag tatgtaatct
    30781 ttccatttct gtttttaact tttctctttg accttcttct accttcatat actctttcac
    30841 cctgttttct ttttagatat tttctttctt attttactat agttatgtgc gttaagcgat
    30901 gaaaaacagc aaagattgga aggatctttg ctgttttttc ttaaaatatc cagttgagta
    30961 caggatcaat ctgtttcatt gtcctcttga tccgtcgtaa tattgatcga tgtgtcttta
    31021 gcagtgatct ttagcttttt ctgtccttgt tctaacaaag tatttgttat tggctggtag
    31081 tctttttcaa tataagattc accagacgtt tggatagtat agccactgtt ttccatctca
    31141 tgcaaagata aattgccacc gtttaggatg acttttcctt ctttgctgat caaactgtct
    31201 tctagatgga agttgctgtt ttcacctgtg acgatcaagt tatccacatt ggcctcatct
    31261 aatcgaagtg agcctaattc atctttcgca gttattgttc ctcctgtaaa ttcattgaac
    31321 gatacccagc catcatgtgt cttagtattc acttttttga ttgatacttc gttgatatca
    31381 attgcactat tattcccttc gattgtcaat tcagataatt catgatctgc agggacaaca
    31441 atagtgattt gtgcacttgt gtcttctaaa ctaatgattg cacctgttga ttttttgact
    31501 gcattcacag tcaacacgcc atttttctcc tttatttctg gcttttctgt cttatcataa
    31561 gtcgttttta tctcaaaatc caatccgcgt atgaccgaaa ctgtttgatt ttctgcatgg
    31621 atgacgattt tgtttgcatc cttgattttt tttgtctcag taaccatatc gatcaaccga
    31681 ggaccattat cccaagtcag actcttttga gcgcctaatg tataagttgc acctgctagg
    31741 aggccaccag taagcatcag accaataccg gtaatcaaaa aatgtttcaa tctcaattta
    31801 tgtgtcctcc ttcaaacgcc cgctgaatgc agatctcttt ttgtaataaa acgtcgtccc
    31861 atccatttaa caaagttcat catgacataa aaaagccctt ttgttccttt cagcaacagt
    31921 ggcgaaataa atactgcgct tcctgtggcg aacagaccga caccgataaa gaataatcca
    31981 ctcagaatcg attgtccaaa cacactgatt cctgagatga tcatgaatag gccaacacct
    32041 aagatactga tacataaaac atagatacta aaaatgagcg ctagtaaagc aaccaatagt
    32101 cccccaataa ccaatataaa ccccagtgct agtggaatga ggacaggaga agcaaataaa
    32161 ccgataatga ttaaccaaat caggcgaatt tgtctttttg gatttttcac taactcgttt
    32221 tctgcttgtt cttcttctga aaagtaactg atttttaatt ttaaggcaaa ctgctttggt
    32281 gtaccatatt catcaatgat ctgatctaat gtttttccag aatctaaaaa atattcctca
    32341 taatactgga tcaaatcaaa acgatcgtct tcaggaattt cttgaagatg atccacaact
    32401 tcattcaaat attcattcat ttgtgctctc ctccaataac cggtctaaag aatctcgaaa
    32461 aacaatccat tcatcaataa tttcttctaa atgacgactt cccattggtg tcaacgagta
    32521 atatcgacgg tttctgcctt caaaaggttc atcataggtc tcaagatatc cttctttttt
    32581 caatcttctc aaaaccggat atagtgtaga ttcactgaca gagagacttt cttgtacgat
    32641 ttttgttaag gcatacccat acatatcttc cttgcttaat gctgctagca cagtaccatc
    32701 aagaagaaca gttggaatct ggatgtgcat tacgtcacct tctattctca agtgtaatat
    32761 tttatttcaa tctatattat acaacatata atatagtttc aaaatcagtt tgtcaaatac
    32821 aaaaaaactg actaaaagat ttgatccttt ttagtcagca aaaaatggct tctctttgat
    32881 ttttattata acagtggcat aatccaattt gtccacatcc agctcagtgg catgataacg
    32941 atcattgcag gtatcatgtc agctactggg aacattttca cgttgatcat tctaaaaccg
    33001 gtagcgacca tcaagaatcc gccgcaagct ttaaaatcta agatcatgtc tggtgtagtc
    33061 aatggataaa taaattttgc caataagaac aaaatataaa aaataatgaa ttggggaatt
    33121 gctatcacag aaacgacata ccctaaatta cacgcaaaaa tagctgctgt gaaaaaatca
    33181 aggacagatt tagaaatcaa aatcgtactg tctcctgtca tcccagaatc taaacttcca
    33241 tagatccccg taccacttgc acaaaataga acaatgaccg tcactaatgt gctgataaat
    33301 tcatcgtggg tcataccaag cttttcacta gggaagattt tagaaatagg tacttgcatc
    33361 agcgcagccc ccttatttat cccattacct aaatgaacaa tcaaaccaat cgctgttcct
    33421 atcactaaag caaaaataac agccggcata tttttcatcg gcgcaatgga atagattccc
    33481 atccccatcg aacacacacc aaaaaccatc gtcagctgtg ctttaaaatg ttcacttaat
    33541 ttatttccta ctaatccgcc aattagtccg ccaaacaaaa cggaacctac attgatcaaa
    33601 actccagttg gcatcaaaaa actcctctct ttttctacga agcgaaaaaa atcagaaaaa
    33661 tttctgtaat tattgctttc gctgcaagaa agattgtaac agacagagaa gattacacca
    33721 attcattttt tgtgttaaag tattctttat tggaataagt aggaggaata tgatggatat
    33781 ccataaattc gaagtttttc ttgatttagc cgaaacaatg aatttcacca aaactgctga
    33841 tcgacaattc accacccaag gaaatatttc taaacagatt ctttcgttag aaacagaatt
    33901 agacgtcaaa ttattcgaac gcgcccatag aaaaatcgaa ttgaccgaag ctggaagctt
    33961 attgctccca tatgtaaaaa atgtcgtaga acaataccat gctatgcaag aagtgcttga
    34021 aacctatacg aaagacaaca atctttcatt aaatatctta acgataccga caatgatcaa
    34081 ttataaaggt ttttccaaaa tcaccgagtt tttgaaacgc catcctgaat ttacagtcca
    34141 gttgaaagaa gtggaaagtg tcgaattaac ttacaatgac gccaatgaac atagtgacac
    34201 gatccacttt gctagaagtt tccaggcccc accaagttcg attgagtggt tgcctactga
    34261 aacagacgat tttgtagcag ttctacctaa aaatcatcct ttagctagta aaaagaaatt
    34321 ggatctaagc gaactgaaaa aggagaactt tttgctcctt ggccccacta cgaacttgta
    34381 tcaacctgta ctagatctgt gtcgcgaagc tggatttgaa ccaaaaatct cttataaagg
    34441 agcaagaatc gacttgatca tcaatatgat tgcaaatgac atggggattg ctattgttat
    34501 ggaaaaaaca gtcaagaatc tattaaaaga aaatactgtg attctcccta tttctccaac
    34561 aacagagagt tatcttgcat ttactcgtaa agtcggtgag cattctttgg cttcagatac
    34621 attttgggag tatttaaatc aagaagaaaa ctaagcccta cattttctgt ccatctatcc
    34681 acccaaaaaa agagagcgac gcatgacttt cgctctcttt cttgcatcat gtccttgttt
    34741 caatgacacc tctaacattt ctcgtagttc aataagaaag cagcgatttt tatgccaaaa
    34801 gaaccgtaag aacatttccc taatcacaaa aaaacgacta aaaaccccta aaaaccttca
    34861 atagaatttt taggggtttt attctttttc ctattgttta cttaaccgta tcattgctgt
    34921 cgttcctact ccttcgatac tgctataatc aatacgtcca tcatgcagtt ctagaatttt
    34981 tttaaccagt gaaagtccta gcccattccc agaaatttga cgacttgtat ctccttgata
    35041 aaatttttca aacattcgat ctctggtctc ttcattcatt cctacacctg aatcggtcac
    35101 ttccagtaca atctctgtgg ctgtctcaaa tagtttgata tgaatctgtc cattgatttg
    35161 attgtacttt atggcgttat ccatgatatt cagccacact tggtacaaaa actcttcatt
    35221 gcctgtgtaa tttactgcag caagttcgat atccaattct agctgttctt tctcccattt
    35281 aggctgaaaa aaaacgatta cttctctgat ttgttcatct aatcgatact ctttcttttc
    35341 cagttggata cgctggtttt ccagtttgtt caattttaag atgttctctg ttaattgtga
    35401 aagctgcgtg atactttcga taatccgata taaaaatatt tggcgttctt cgtcagagag
    35461 atttggggct tgtaacaatt gaacatatcc ttggattgtt gctagtggtg ttttgaattc
    35521 atgggataca ctggacacaa agtcattcct cagtgtctcg atactattga gttcttggac
    35581 cataacgttg aaatctttat acagttgctg tacttctgct actttctgct gttcatccat
    35641 tcgaatcgaa aaatctcccg ttgctaccag actcatattt gtccctagcg cactgattgg
    35701 atgcaggata cgccgcccaa caaaaatcga tattcctgta cccacgacca tactgaaccc
    35761 cgcaaagacg aataacgggt ataacgttgg ttttccagcc gattcagcag gcgagataga
    35821 atgtcgagac aataagaaaa taaaaccgag aaaacacagc agtgtcacta agatcgaaat
    35881 gaagacaata ctagcaaaat agatccataa ttgtgaaaat agcttttttt tcatctttaa
    35941 ataaccgcct tatagcctag tccccgtact gtgatgattt gaaaatcttc cgtcttttca
    36001 aaacgggtcc ttaaacgttt gatatgtaca tcgatcgttc gttcttctgt attcgtatct
    36061 aatccccaaa tatcatccat caactgttgg cgagtgaaga tcttgttggg ataagacagt
    36121 aatttataca gaagcagaaa ttctttttga ggcagaatca acgaatgctg atcttgtaac
    36181 actgtataag catctagctc taattttgtt tgtccgatta tcaagctact gctgtaattg
    36241 atctttgaac gtcgaagcaa tgcttccaca cgtaggatca tctcattgac atcgatgggt
    36301 tttgtcatat aatcatctgc tcctaatttg aacccgcgtt tcttatcctc aaaatcggcc
    36361 tttgccgtaa tcattagaac aggtgtgtca aatctggtgc tacgtaatga gtctagcaag
    36421 tcatagccat ccattttcgg catcatgata tctgtaatga ttaattctat acgtgtcgct
    36481 tctagttttt tcagcgcatc ctctccattc aatgcggtga tgactgaaaa gcccgctcgt
    36541 tccaacacag aacggtaaag caactgtaat tgcggatcat cttctactac taaaatacga
    36601 ttcattgatc tccctctgtt ttttgaaaaa tttctagatt ttttcttgta gttcatcttc
    36661 agttaacatt tatttcgtat actacgatca ttgttctgat atacttatta gtataccgaa
    36721 tatttcaata cgggagaagg gtgattatgc ttcaattaaa agatataaaa aaatattata
    36781 aagtcggcga aaccaccacc aaagcattgg atggtgtgtc tgtcgctttc agacaaaaag
    36841 aattcgtagc gattttaggt cctagtggtt ctggtaaaac gactatgctg aatgtgattg
    36901 gtggactaga taattatgat tccggtgata tggtaatcaa cggaaagtct actaaagact
    36961 ttaaggacag tgactgggat gcctaccgaa acaactctat cggtttcatt tttcaaagtt
    37021 acaacttgat tggtcatcta ggcattattg aaaacgttga acttgggatg acattaagtg
    37081 gtgtttctaa agacgaaaaa cgaaaacggg cagaagatgc attgcaccga gtcggcttga
    37141 caaatcatat gcataaaaag ccaaatcagt tatctggtgg acaaatgcag cgagtggcca
    37201 tcgctcgagc actagccaat gacccagata tccttttgtg cgatgaacca accggagcgt
    37261 tagatacaga aacaagtatc cagatcatgg aattgatcca agagttatcg aaagaaaaat
    37321 tagtgatcat ggtcacacat aatcctgaac tggcccatca atacgcagat cgaatcattg
    37381 aattttctga tggtaagatc ttaacagatt cccatcctca catcgaacga ccaaaagatg
    37441 atcaatttaa cttacgcaga acaaagatga gtttttggac agcgttaaag ctttccttca
    37501 acaatatccg aacaaaaaaa ggacgtactt tcttgacctc ctttgcttcc agtattggga
    37561 tcatcggaat cgcgatcgtt ctgtcccttt cttctggatt ccaaaaacaa atcgataaca
    37621 cgcaagctga aacgatggcg aaatttccga ttactatttc taaggtaacg actaaccaga
    37681 ctcgtgacga tgccggattg ggtgcaagca aagcggatta tccagacagc aaaacgatta
    37741 ctgcaaaagt cagcgaagaa gataaagcac agcacacgaa taagattgat caaacatacg
    37801 tcgattacgt aacagacatc gatcctaact taagtaataa tatcggattt acccgtacta
    37861 caggaatcaa tcttttacgt gatgtaaatg gcaaagtaca gcctgtcagc ttctcgaatc
    37921 aaaatcctga tacggaatct ctttctttat ctagtacgat gtcagcaatg acaggtgtgg
    37981 gagtgtcaag tttccctaca cagcttgaca ctagcaaaga aaacttttta aaagacaatt
    38041 attctttact tgccggaagt tatccagcct cagcaacaga tgtcgtgctg atcgtagacg
    38101 gcaataataa tactaatatc aacgcattga agaatcttgg atttgatgtg aaagaagacg
    38161 aaaaacttga ttttgatgat atcgttggta caacattcaa attagtaaac aacaatactt
    38221 actatacaaa acttccaact gggaatttta tccctaatac agattatgat gcgatgtatc
    38281 agaatgcttc tgatgaattg aagatctcgg ggatcctacg cgtgaaatct tcttctacaa
    38341 tgaatctctt atctccagga atcgcttata gcgatcaatt aacgactcaa atcgtcaacg
    38401 aaaacaaaga atcagaaatc gtcaaagctc aaagagacag tggtgtaaat gtcttaacta
    38461 ctgaaaaagt tgacgaaaat gccaaacaaa cattgcttag ttatttaggt ggagacagct
    38521 tgccttcaag tatcatgatt tatccgaaca attttgaaga caaagaaaag atcttggatt
    38581 atctagatga ttacaataaa ggcaaatcag atgaagataa aatcatttat actgatttag
    38641 ctggaacgat gactgaactg actggcggat tgatggatgc tatcacttat gtccttattg
    38701 cttttgcagg gatctcttta gtaacaagta tgatcatgat cagtatcatt acttatacat
    38761 ctgtgattga acggacaaaa gaaatcggtg tactaaaagc tttaggtgca cgtaaaaaag
    38821 acatcactcg cgtatttgac gcagaaacgt gtattttagg tatttcttct gggatattag
    38881 gtgtgtttat tgcatggcta gctacgttcc ctatcaatag catcttatac aacatgacgg
    38941 atctaaaaaa tgttgctcaa ctaaatcctg tccatgcgat tattctagtg atcgtctcta
    39001 ctatattgac gatgcttggc ggtcatcttc ctgcacgaat ggcagcgaaa aaagacgccg
    39061 ctatcgcttt gcgtgcagaa taaggttgtg acaaccacat ttagatttga gtcataagag
    39121 cgctgaaata gtagaaaaca gcaagaaacg aggaagtaat atgttccttg tttcgcgctg
    39181 ttttttttaa ttatttttta taattctggt atacttttct ttcctttgta ccacaactct
    39241 tctggcgtat acctgtcttt tccatttatg aatactgttc catctgcttc aatcgttact
    39301 tcagtcccaa tccacatatt acgagaaagt gcgagaagat tttttctttt tcctcttcct
    39361 ttttttccaa attgcaaggc atcggttatc tcttctgtcc aatgagattt cacgtatttt
    39421 acttctccgt tttcaaatgt aactttcaaa atattcgcta tattttccac ttttactgct
    39481 ttaggaaatg actcctccat ttttttcact ttccttcctc caacactaag tatgcgcttt
    39541 cttttagtga taagtatatc atagtttatt ctattatcaa aaaaacgcat ccattccatt
    39601 gtagaatact ttaccgaaca agttgaattg ttttcctctt tttcaccttt tactatagat
    39661 aggtaaagac aactaaggag gaatctctca tgacagatca accgtatgat ttaagaaaag
    39721 tcatcgaaga actaaaaaca cttccaggtc aatatcacga aacagatatt gaaatcgatc
    39781 ctgaagcaga attatctggt gtttaccgtt atatcggtgc tggcggtaca gtaaaacgtc
    39841 cgactcaaga aggaccagct atgactttca acaatatcaa aggtttcccc ggcacacgtg
    39901 tgaacatcgg aacaatggct agtcgtaaac gtgtaggtga aattttgcac catgattatc
    39961 gaacacttgg tcgtttcttg aaagacgctg tagaaaatcc aatcaaacct gtgaaagtag
    40021 acaaagcaga cgctccagca caagaagtcg ttcatctagc taccgatgca gacttcgata
    40081 ttcgcaacat tttgcctgca cctacaaata ctcctgaaga tgctggtcca tacatcacaa
    40141 tgggtgtagt cttaggatca gatccagaaa aaacaatgag cgatgtaacg atccatcgta
    40201 tggttctaga agataaagat acgatcggta tgtacatcat gcctggcgga cgccacattg
    40261 gtcacttcca aaaacaattc gaagccttga ataaaccaat gcctatcact atcaatattg
    40321 gtttagatcc agcaattgcc attggcacga ctttcgaacc acctaccact ccacttggct
    40381 acaatgaact atggtgtgca ggagctttgc gtaacgaacc tattcaaatc gttgatggta
    40441 tagcagtcga tgaagtgggt attgctcgtg ctgaattcat cattgaagca gaaatcatgc
    40501 caaatgaaac aatgcaagaa gatatcaaca cgaactcagg aaaagcaatg ccagaatttc
    40561 ctggctatac tggggatgct aatccagctg tacaagtagt gaaagtcaaa gcagttactc
    40621 accgaaaaga caatccaatc atgcaaacaa cgattggtcc cagtgaagaa cacgtatcta
    40681 tggccggtat tcctacagaa gcaagtattc ttgccttggt cgataaagct attccaggaa
    40741 aagtagtaaa tgtctacaat cctcctgcag gtggtggtaa attgatgacc atcatgcaaa
    40801 tccgtaaaga aaacgaagcg gatgaaggta ttcagcgtca agcagctatt cttgctttat
    40861 cagccttcaa agaattgaag acagtcattt tagtcgatga agatgttgat attttcgaca
    40921 tgaacgatgt agtttggact ttcaacactc gtttccaagg agataaagat atcatcgtga
    40981 tcccaggaat gaggaaccat ccattggacc catcagaatt accagaatat aatcctggct
    41041 ctattcgttt ccgtgggata agtgcaaaaa ctatctttga cggtacagtt cctttcgata
    41101 tgaaagaaca ttttgtacgt gcaaaattcc aagaagtaga agattgggaa aaatatttga
    41161 aataatgaat gatctgcaac tgttttgaca tcataaaaag gagtgcggaa aatggaacaa
    41221 ttggcacaac ggaagaaaaa aatcgtgatt ggtgtaagtg gcgcttcagg caccatttat
    41281 gccatcaacc tagtgaagaa actaaaagaa tatccgatga tagaaacaca cggaatcatc
    41341 agtccatggg caaaacagaa cttaaagctg gaatccgact tatcactaac tgaattcgaa
    41401 agcctgtttg attaccatta ttcaaacaaa gatttaggtg ctgctgtcgc cagcggatca
    41461 tttttgaccg atggaatgat catcgtaccg gcaagtatga aaacagtcgc aggtatctct
    41521 gttggtttag gcgacaacct gattgcacgt gctgctgatg taacaatgaa ggagcaacga
    41581 aagttagtca ttgttcctcg tgaaacgcca ttaaatgcca ttcacttgga aaacttgact
    41641 aaattagcac gactaggtgt gcaaatcata ccaccaattc ctgcttttta taatcagcct
    41701 caaacgatcc aagatcttgt taatcaccat acaatgaaac ttttggatca atttgaaatt
    41761 gtaaatgagc attcaaaacg ttggcagggt gattaatatg gaaaaagaaa cgatagttga
    41821 agtaaccaaa ctaggtttca cgatccaagc tgctgttaaa gtaatcggta aagacttatt
    41881 gatcacttta acaggcggag atacaccaca tatcggaaca gtcactacat tttctcgtga
    41941 tacagagatg caaactgtac gtttccctag ccacgatggt cggttccata aagacgatgt
    42001 cttagccgaa aaaatagctg tgatcatcaa aactgccgtt ccgggaagtt gtacgatcac
    42061 ttccggtatc catgttgacc atatctccaa tgcacaaatc aacgcctctt ttccgatgtc
    42121 agaagagtta ggttacaaga ttttagattg gttggaaaaa atagatttcc atatcaaaga
    42181 accagtttat tataaagatg gtgaaaaacc attatgaaag aagaggttgt gaaatcagcg
    42241 ttatgacctg agtatgagag aaaaaaatgg aaaaatagct tctcatattt tgccgttttt
    42301 gagctaatac cgagggacag ctgattgaac gccgtttatc aagaggttgt gataaagccg
    42361 cttcgtttcg agtagtaaga aaaattttgt aaacatgggt ttccacattt ttgcataaat
    42421 ttgacttact accgagaaac tggcttttga acaccgttta tcaagaggtt gtgacacgtc
    42481 ttttgtcaca acctctttta tttttgcttc actgtaactg ctacaatatc accgatttct
    42541 tttccgatgt ttttacgaat atcttttcgt aatccaagga tgtagcagac tgaaccatct
    42601 ggatttttca cgcccatatt cacgatactg ccttcatacg gcacattgtc aaaagttgct
    42661 tggactttaa ctcttccagc accgaattct tttcttatat catacggaaa aataatatat
    42721 gccccgccct tgccgacttc ggaagcatag atttttgatt caaaagaata aatttccctc
    42781 attttatttc tcctattttt tacatctagt atagcatagc aaaaaaaaga aggaactgtg
    42841 acaaaagtct tgtcgcagtt ccttttttcg aataaacggt gttctcctgc caactcctcg
    42901 gtcacaagtc acaatagtca acaaacatga gaagctgttt tttgaaattg ctccttgtga
    42961 ctcagagtta aacggcaggc tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc
    43021 tacggcacta agcccaatca gatgaaaaat atggagtgct atttttatct gattgttctt
    43081 actgcttgat gcagagcagc tttttcacaa cctcctacat ggtgttcaaa atattattcg
    43141 ccttttgctt ctttcactaa ttttgcgaat gcttgttgtt ggaattcagc agctaaggct
    43201 ttcgtacgtt gttcttgctc tgctttgctc atttttggat tttcagtcat tgcttttacc
    43261 ataccgtctt gaacataagc ttttgcttca ctttccatcg tactttgctg tttcttcact
    43321 aattcagcta acttggctgc ttggtccgta cttaattcta cccatgtctc tgggattttg
    43381 aatgtattca ctcggctgtc atattcgtga ttgttatcag caatattgaa ccagaattta
    43441 tacatgtcgt ttttgtattc ccaataagta gttttcgtca ctttttcagc atcgccgtct
    43501 gtcttttcta ctttatttgt ttcgttatcc gtaccagttg cttttggttt ttcttgtttt
    43561 tcatttgttc ggtaaagata cactttttct tttccattcc ctaaagcttt atacaaaagc
    43621 atatctgctc cttgggaatc agcactggaa acaatttttt ctgtttttgt ttccgttact
    43681 ttttccattc caaagtgatt ggacaaatta gcgacgatca aacttagtga agcgacgaag
    43741 attagtccga aaatcaaaga taaaaaggtt tgccatgttt ttttagcgaa cacgttcgtt
    43801 aaagcaaaag caagcaagct gacaatcaaa actccaataa tcatgcatta tcccccgctt
    43861 tcattagaac aggttctttt ttcttcaata aaaaggcaat aataaagcca agaatcccaa
    43921 agatgatcgc tacgataaac gcggcatggt aacctgacag tgtggcattg attgcctgat
    43981 ctttataagc taatggcgta ttatccaata cagatttgct tgggatattt gcttttgtca
    44041 cattcgtcaa cacactgatc aaaatagctg taccaatcga gcttgcgatt tgacggaatg
    44101 tattatttac cgctgtccca tgactgatca agttatttgg caatgcattc ataccagaag
    44161 tcgttaccgg catcatgacc atggagatcc caaacatacg gatcgcataa aggatcacga
    44221 tatataaaac tggagtcgtt tttgtcaaga aagcaaatgg tgcagttgcc gctgtcaaaa
    44281 tgaacatccc tgtgatggct aaacgtttcg cgccgtattt atcgaaaatc gcacccgtca
    44341 caggcatcat agcccccatg atcaatgcac ccggcaacaa catcaagcca gaatggaatg
    44401 ctgattctcc acgaatattt tgaatataca atggtacgac catttctgcc cctaccatcg
    44461 ccatatttgt tacaccagct aaaacagctg caatcgtgaa tgtagatgat ttgaatacac
    44521 gaagttccaa gaatggatgt tccaaatgta attgacgcca tgagaacaag gcgatgaaaa
    44581 tcacaccaac aactaagaaa ccaattactt tcaagcttcc ccagccgtca tctcctacac
    44641 tagaaaatcc gtaaagtaaa ctaccgaatc caatcgttga taaaatagcg gataaaatat
    44701 caatgctagg atttgacaat ggaataacac ttttcattag gaagaatgct aaaaccaaga
    44761 caagaacaac gattggcagt accataccaa acaagtcacg ccaatggtag ttatcaatga
    44821 tataaccaga taatgtaggg cctaaagcag gagcaagtcc aataacgatc cctgacatcc
    44881 ccattgctga tcctcttttt tctggcggga aaatagatag catgatattt tgcaataatg
    44941 gcatcgatac tcccacaccg caagcttgga tcaaacgacc gattagtaat gtactaaaat
    45001 taggtgctgt aaagcaagta atcgttccga tcaaaaagat cgtcatggca gaaagatata
    45061 aatttcttga actgaattta ttgatcagcc atgctgttat tgggatcatg atcccgttga
    45121 ctagcaagaa accagtcgtt aaccattgca catcagacgc tgaaatatcg aaagctttca
    45181 tcaatgtagg aaaagctgtc gtcaataagg tctgattcaa aacggtacaa aatgtaccaa
    45241 ttaataagac aacaactaaa agtgtccgat tatatggttt tccgtaaata tctacgggtt
    45301 ggttgttact catatttctc cttctttctg aattttttct gaaactacta gaatacttta
    45361 gtcctaaatt cgctatttgt caacctactt gacacataag ttaatacgga tataattaag
    45421 ggaagcaaga ggacaaaagg agtgacaaaa atggttgggg cttcccttaa acgtttgttg
    45481 gaaaatgatc aattggttgt tggcatcagt gaattaagtg atatcgtagg tgtgtctcca
    45541 cgtcaattaa ggtattggga acaaaaggga ttcattcgtt cgatcgaagc tgatgcgaat
    45601 tgtcctagaa aatatcgttt acctacagtc ataaaagtag aactgatcaa aaaatattta
    45661 gatgacggat ttactttgtc aaaagctgca gaaaaggcag aaatccgcca aaagaaaatg
    45721 caccatgtcc gtaaagtttt ttcaaaagca atcaaagata tcgaattgat cgacgaacgc
    45781 tatacgattt tacaaatcgg taacttcaaa gaagagaatg ctaagatgta catcattcat
    45841 gacaacgaga cagacgaatt aacttacaag ctccttcctg tcgatgaaaa agctgactac
    45901 gaacagttgt taaaagaact ctaaacgcca ctaatctcct aagtaccaag ctttttaata
    45961 agtagatgct acataaatac ttgaaaaaag gcctgtttga acataagaat atccgaacgg
    46021 tgatctgcgt ttctttcata tagaaaggaa ttctccatca ctgttcggat atttttttat
    46081 ttttttcggt tactttcttc taatacatct gttagccaat ttgcatattc tgtttcccga
    46141 ttgatcgcat gcgctaaaat caggtagtgt ccgtaatttt catgtttttc tttttcagta
    46201 ggaaagatcg ttttttttcg ctctaataga tgaagtcgtt tttcttcatg aaggtcacgc
    46261 tgctgctgaa taatttctac taatgccgga tcattcacgt ctttgacgaa atacaatttc
    46321 agaacaaatt cgtctcgatt aaccggtagt tcattggtgg gtgtatgaat ccactctgcc
    46381 aattgttcct tcccttcttc tgttaattca taaactttct tttccaattt ttcacctgtg
    46441 atctctactt gatgctgaat gattccttgc tcttccattt ttgcaagttc aggataaatc
    46501 tgactatgtt ttgcttgcca aaattctcct atttcatttt tgaacgattg attcaattca
    46561 tatcctgtca tcttcttctt acttaataac cctaacaaaa tatatcgaag tgtatttttt
    46621 cttgccatca gttttccctc cttgacaaat ctttaaatcc attctatcat aaatgagtaa
    46681 tcgaaaacat gtagtttatt acatgtttta atttataagg agatgcttaa acatgaaaga
    46741 atttaaagaa ttggaagatt ttattggaac tcactttatc tatacgtatg acaatggttg
    46801 ggaatatgaa tggtatgcca aaaatgacca tactgttgat taccgtatcc atggcggaat
    46861 ggtcaaaggc cgttgggtaa aagaccaaga agctgatatc gttaaattga cggacggcgt
    46921 attcaaaatc acttggacag agccaacagg gacagacgtg gcattggact ttatgccaaa
    46981 tgaaaagaaa cttcacggaa tgatcttttt ccctaaatgg gttgaagaac atccagaaat
    47041 cactgttact ttccaaaacg aacatatcgc agaaatggaa gcagctcgtg aaaaatatga
    47101 aacttatcca aaattacttg ttcctgaatt tgctacgatc acttatatgg gtgatgcagg
    47161 tatagacaat gaagatgtta ttagcgaaga accatacgat ggaatgccag atgatatccg
    47221 tagcggaaaa tacttcgatg aaaattataa acgagtaaaa taaggttgtg aaagagaggt
    47281 tgtgaaatca gcgttctgac ctgagtatta gagaaagaaa cggaaaaata gttcctcatg
    47341 ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tatcaagagg
    47401 ttgtgaaatc agcgttatgc tttgagtaat aagaacgcta gttagaaaat agcttttcat
    47461 attttctagg ctagtgggct tattaccgag aagcagccgt ttgaacaccg tttatcaaga
    47521 ggttgtgaaa tcagcgtttt gacctgagta ttagagaaac aaatggaaaa atagttcctc
    47581 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttatcaaa
    47641 gattgtaaca actgcatatt cacacagtta aattagtgac ttcaaaatga aataatgctc
    47701 ccagcaaaaa attaggctgg gagcattatt tcgttattct gttcatcaaa aatcagcgtt
    47761 ttgattccat ttcatcacaa gttcctcctc atttactgct tcatcttttt gctgtgtttg
    47821 aattgtaaaa ccttgtgaaa gatagaaatg aatagctgat tgattttttt gatagactgt
    47881 caaagtcagt gttttattgg tttcttttat ttttttcatt agttgcgtac cgattctttg
    47941 ttgccggtat tcccttttca caaagattcc tgcgataaac tgatcaatca ccccagcaaa
    48001 accaataatt tcttgatcta tttctgctaa gtaaatcact gcatctggta aagctttcct
    48061 aacagattct acttgattct cccaataagt tgatggaatg aattcatgag aatccaagtt
    48121 agcatgcagc caaatcgata gaacagattc cagttctttg gcagacaatt ttgttgttgt
    48181 gcggatcatt ttttctctcc ttacttattc attgatttta aaataaaaac catttttttg
    48241 aagctctttt acaagttttc gcccctcaaa aaagtatatc ttctcttgtt ttacttttct
    48301 aataccaaaa gaaacagcaa ctttaggatc atcagctgaa acgattcgat aagttccacc
    48361 aggcaattga tccagcttga ctttcccatg atggtcgctt tgtactgaaa acggcacacc
    48421 atttctagta agtgtttttt tcttatgttt caaaatgaat gaactaccat ttaccggttt
    48481 ccctgacgaa tcactaataa taaatgaaaa atcaagcact tttttactta atctatactg
    48541 atagattagt cgtccgataa acactaacag tatgactaca gctattatcg ttcctgcaag
    48601 aataaaccat tgccgcatgg ttctttcctg atttcctttt ccttcttctt tttttaccga
    48661 ttcgttataa ggaatccgat gtcctgtcac tagcaaacga tgcgtgttga tcatatacgg
    48721 cgtacatgta agcaaggtaa ctaagtcttc tccttctgaa atcgttagaa cagacgtgtc
    48781 atctggcagt accacttgta tatttttaac ttgataagcc aatttctccc ccaaaacagt
    48841 caaaataaac gtgtctccgt tttctaaacg atctaattcg gtaaataacc gtcgattagg
    48901 taaaccgctg tgagcagaga tcactgaatg cgtcgaattt ccaccaagcg ggaaagaggt
    48961 tccttgcaag acgcctgctc cattttcaag gatcctacca ttgagccgat cataaagtga
    49021 aatatttaat tggatcttag gtatattgat acttccgatc agccattcct ctaattggct
    49081 ggatgttgta ctttcatttc tgttcttttc attgaaagga tcagtaccag gattgaatcc
    49141 ttggtcagtt aatcgttggt ttttctcctc cattttcttt cgctgcactt caatttcagc
    49201 tgcggtccgt ttttgtactt gttcgatacg tttttgatca ataaaactat ttaaagaatc
    49261 cacataaaat ggatataaag cgatcagtaa ccctacgacg atacatatta ataaaaacaa
    49321 acgaaacaaa agtcgacgag actgtttttg cttactctgc ttcacatgtg tcctcccttg
    49381 caagtttttt tgttctttct tttattatat gggttcagga aaaaaataga aaatgaaagc
    49441 cgatgaggtt gtgaaaaagc tgtcctgcat caagtaataa gtacagccca aaaaaatagc
    49501 tactcatatt ttttgttggg ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    49561 taaggaagag gttgtgaaaa ctgcgttatg ctttgagtaa taagagcgct agtcagaaaa
    49621 tagcttctca tattttctag gctagtgagc ttattaccga gaagcagctg attgaacacc
    49681 gtttaccgag aggtcatgaa aaagctactt tgtttcgagt attaagaaaa attctgtttc
    49741 aaaacaagga gatgcaacaa aacttatgtc gcatcctctc tccttagaac tttcacttat
    49801 gtttttcttg taaaattcat aaatattttc atgaattttc taatttcttg cctacctctc
    49861 gcataggata tatgatgaat ttatctaaag tttgcaaagg agttcgacaa ttgaaaaaat
    49921 atggcccatt tttagcaatt tttttcattg ctttggcatt tctcatgcct catttattca
    49981 cacataaact aattttgggt gctgatgccc cattccatta caatcggttc tatgatgccg
    50041 cgcaacaaat taaatatggg gatttccatt attttccttc cctttatgga ttccagcaaa
    50101 gtggcaggat cgtgaatgcc gtttacggcc catttttcgc ttatttacaa ggattgatcg
    50161 tgttgcttgc aggtagctgg tttcattatc agattctttc aaatttcatt ctttatctta
    50221 tttcaggatt ttctatgctg attttactga gatatgtcaa tgttcgaaat tgggtaagtg
    50281 taccagtagc cgttttattc atgagtacgt attctattca atactggtct atcaaccaag
    50341 gattcactag ctgggggact tgtttttatc ctttatgtat gatccctatt gctgatttcg
    50401 tccttcataa aaagttccct gttatcaaag tcgctgtctc agtgggactt atgacacaga
    50461 tccatttact gtcttcgatc atgttagctt tgatgtatat ccctttttat ctttattact
    50521 tttttaacca gactgaaaaa ggaaaagcac tgcttcaact gattaagtcg gtcttgcttt
    50581 attttgttct gacagcaaat atttgggcag gattagctat tgtttacagt gggaataaga
    50641 ttcttcctcc ctttgttaac agagaaatga gtcaaaaggc gatagatctg gatggcagtt
    50701 attggctcca ttaccctaag gcctttccta tattgatatt atcaggtttt ttgcttttta
    50761 ttttctttca acaaaagaac accttattcc aaaaaatcgt gttgtacaca agtcttgttt
    50821 tcttttttct ttctactagc ttgattccat ggacgacatt gatcgaaaaa aatgtgcctt
    50881 ttattagttt gatccagttt ccatttcgat ttttcgtgcc atttacgcta ttgcttctac
    50941 tttaccttgc cctttcactg aaccagtggt ctgaacaaaa gtggttccgt cttttaagta
    51001 tatttggcat tcttattttt tcagcacaga cgatccagaa cttataccag catctggaaa
    51061 agtgggaaaa tgaaacattt gtcagtcgac atacttatct attcgatacg ccggaagaag
    51121 caaggaaaac attcttcagc aaagatatgt ctaccagctt gttcgttttc caaaaaacca
    51181 cacctgacta tctgccaatc tataaggaga caaaagacaa taaatacgac cggtataacg
    51241 aagaaatact agaaaacgaa acaactttta taaaaacaca tccaggcggt cttttgacaa
    51301 tcaagtggaa aaacactggg gacaaaactg ttcatatccc tgttatcgtc tacgatcgga
    51361 ctgtgctaca gcaaaatgga aaaacattga ctgattatga agtaacagat atcgggaccc
    51421 caatcgtgaa gcagcaaaaa ggaatcaacg agctcacgct tcattatcaa acgccaatct
    51481 atttctattt cattctttct cttactttga ttggctggtt taccttgcta tgtttattta
    51541 tttatcatag atacaagctt ttacgtgctt aggcaaaagg gataaataca tccgatcaaa
    51601 aaactctcca aacggtataa tcgtttggag agttttattt taatcagttt ttttatgtta
    51661 tatgttatat tttttattcg ttcacatcta attcgatttc caccccgtag tgatcactga
    51721 tgattggact atcgatccca tcaaaaatcc gttgatattt tttaacctgc attccttcag
    51781 ggacgaaaat aaaatctata cgcaattttt ctgtattttg ttcccaacca tctattttct
    51841 tttccacagt agctgctttt cctttttcat tcgcgacaac atacgaatct tgaagaagaa
    51901 ggcaactttc tcttacagta taataacctt gagagtctac tggattattg aaatcaccta
    51961 ggaaaaaaag tggtacgcga gtttccaaaa agtagttttc caagtttttc cactcaaaat
    52021 aaaagccact ttttttatct gtccaccaag aaaagtggca gctcgagaca aaaatgtcct
    52081 gatcatctat ctttgttttc ccaatcaaga tcttgcgtgt ctgataatct tctttctttt
    52141 gaaattggga gacggtaagg acctgacttt ccaatgtttt tttcgtaagc agtgcatttc
    52201 cttcttcata tttatcataa ccgatgtggc tcatttccca actccaaaaa tactcttttc
    52261 cgtgttcctt taaaagctga actaaacggt aggcaaaatt atctttacgg ataggtactt
    52321 gattctttac cggacagaac ttcattagct tcgcaggttc tacttcttca gattccagta
    52381 attggttgat ttcttgtaaa gcaatcactt cataatcttc taacaggatc ttatctgcta
    52441 attcttgcaa ttttttctct ggttctggct caagccagct atgcgtgttg agtgtcatga
    52501 atttcattgg ttttctcctt gtcttcattt cgaaacaaaa gggttgtgac aaaatttttg
    52561 tcacaacctc tccagcaaat agtgttctcc tgctaactcc tcagtaataa gctcaatgga
    52621 ccaggagcta ttttttgttt ggctgttttt atcacttggt gcagggcagc tttttcacga
    52681 cctctccact aaacagtatt caaactgctg cttctcggta ataagcccaa ccaaacgaaa
    52741 aataggagga gctatttttg tttggctgtt cttatgactt gatgcaggac agctttttca
    52801 caacctctcc ttacatttta atggagccga tcactttacc agctgtcact gtacctaatt
    52861 gcttgatcac tacttcttct actttatcgt ttgtaaatac gatcatgatc gttggatctt
    52921 tttcttcgtt ttggatcaca tcaagatcca tctcagctaa tttcgttcct gttcctactt
    52981 cttggccttc tttgacagca atctcaaaag ctggctgatt catttggact gtatcgattc
    53041 ccatatggat caaaacttcg ataccatctt tcgtttccag cccaattgca tgtttgctag
    53101 ggaaaatact tgtcactttt ccagcgatcg gcgcaacaac ttctcttgat gttggaataa
    53161 cagcaaagcc gtcacccatc attttttgtg agaataccgg atcttttact tcagataaag
    53221 gaatcacttc tccagaagct gcggaaacta gttcttgttc tatacctaag tattgcttac
    53281 tacctgcttg tccatttcct gtagaaacca tttctggctc tggaatctct gctcctgatt
    53341 gcagcagatc ttcgatatct gatttcaaga catctgcttt tggtccataa actgcttgga
    53401 ctccattgtc tttgacgatc aatcccatcg cccctgctcg tttccaggct tcttcagtcc
    53461 ctactttttc tcgatcattt acacttacgc gtaaccgagt catacaagca tcgacatctt
    53521 tgatattttc ttttcctccc agcaaatgaa tgatctggac cacttgctga tctgctgttc
    53581 ctgttccgct gttagataca acggtttctt cactgtcatt gtcgtaattt ccgttacgtc
    53641 ccggtgtagc aaagttgaat tttttgatca agaaatttgc taagaaatac gtaacaacac
    53701 caaaagcgat cacacacaac acgaagttga taagatctcc acctagaccc gctttgatag
    53761 ctaacggtgt ccgagtcagc aattcgatat tcccaaatga atggacccgc aatggcaaga
    53821 tatctgccat cgcaaatgca gccccttgga tcactgaata aatgacatat aatggcacag
    53881 cagcaaacat aaacatgaac tccaatggtt ctgttacacc tgttagaaag acagccaacg
    53941 ctgctgaaaa atacattgat ttatatcttg ctttcttatc aggatcgaca ttacgataca
    54001 tcgcaaaagc cattcccatc aagatacctg aagaaccaat catttgtcct actttgaaac
    54061 gagccggcgt ccagttatgc aacacaaact catattgcga catatcccct gcacctttaa
    54121 gattcactaa atcagtggcc caagccaacc ataacggatc ttgcccaaat acttgtgtcc
    54181 ccgcctgtgc gcctgataaa atctcatacg atccgccaag ctgtgtatag ttgataggaa
    54241 tcgtcagcat atgatgcaat ccaaatggca atagtaaacg ttctaatgtt ccaaataaaa
    54301 acggtgctag aatcggtgcg ctttcttgtg attctgcaat ccataaacca aaattattga
    54361 ttccagcctg tacgtttggc cacaccacag caagaatcaa tgccacgatt gttgaccata
    54421 agataacaac aaacggaaca aagcgctttc cattgaaaaa tgacaaagca tccggcaatt
    54481 ttctataatt atagtactta ttataagcca ttgccccgac aaatccagcg atgatcccta
    54541 cgaatactcc catattcaaa gctggtgctt ccaatacact tgtaaaaaat cctttaacca
    54601 tgatcttcgt accgaacaga gtgtgggtaa atgcatcttc attcgcaagc atgtcacttg
    54661 tgacaccaaa gatagcccca gtgatccgat tgattaaaat aaatgagatc ccagctgcaa
    54721 atgctccgcc tgctctttct tttgcccaac ttcctcctat tgctaaagca aataaaatat
    54781 gaagattacc aataattgcc caaccaatat tttcaattac tccgcccgtt gtgacaagcg
    54841 gcgtccaatc aggattgatc aagggaattg atttccctat actgatcatc aacccagctg
    54901 ccggcataac tgctaccaca accattaaag cctttccaaa tttttgccaa aactcaaaac
    54961 taaatatctt tttcattccg tttagctcct ttacgcaatc ggtttcgtta aacgtattat
    55021 agcgtgcgtt ttcttttttg taaatgcttt attttttatt tttctgtcta taccattcta
    55081 taaaacctat aatacgtgtg ttcccttcta taattttctc ctaaaaattt atttttttaa
    55141 gcttttttct atgaaatatt ttcttttgtc tattgacttg tgcaatcggt tgcgtttatt
    55201 atgaacgtat aaaacagctc attaggagga gaaaaatgaa acagatcaaa cgactatttg
    55261 ctattgatcc atggaaaatc agcacgacac aattagataa aaaaaatctt cgactgcaag
    55321 aatctttaac aagtattgga aacggttata tggggatgcg cgggaacttt gaagaaactt
    55381 actcagggga ccaccatcaa ggtacttatt tggcgggtgt ctggtatccc gataagacac
    55441 gtgtcggctg gtggaaaaat ggttatccag aatactttgg aaaagtgatc aacgccttga
    55501 actttatcgc gatagatatt tcgatcaacg atcagctgat cgacttggct tctttggaac
    55561 cagaagactt ttactgggaa ttagatatga aaaatggtgt attatctcgt acattcacaa
    55621 tcactacttc tactaataaa gtacgcattt ccttcgaacg ttttctgagc attgtcaaaa
    55681 aagaatcagc ttatatctat ttaactatag aaatgcttga aggtagcgga acagtcaaac
    55741 tcgtatcaaa attggatgga aatgttcaaa acgaagacag caactatgat gaacattttt
    55801 ggaatgagat tgatcgtgga actatagaag aaatcggcta tttgacgact aaaactattc
    55861 caaacaactt tgggattgaa caatttactg ttactgcagc aatgcgccat ttcgttaatg
    55921 gaaaatcagt catccctgac tatcacgaag atactttagc attacatggt tgcttgtctg
    55981 cagaattatc tcaaggtgag acatggtcag tggaaaaaga aattatcgtt cttactagta
    56041 gagatattcc agaagcgcag caagcagaaa aagctgtctc agaattaacg aaccagacaa
    56101 acaattatat ccaagcaaaa gaagagcaaa cagcggcttg ggcagaacga tggaagcttg
    56161 ccgatgtggt catcgaagga gacgaagaag cacaacaagg tattcgattc aatttgttcc
    56221 aactattctc tacttactac ggcgaagatg aacgattgaa tatcggcccc aaaggattca
    56281 caggagaaaa atacggcgga gccacttact gggatacaga agcgtatgct gtccctcttt
    56341 atcttgcttt agccaaacct gaagtaacta agaatctgct gaaatatcgg cataatcaac
    56401 tgccgcaagc aatccacaac gctcagcaac aaggattaaa aggcgcgctt tatcctatgg
    56461 tcaccttcac tggtgtcgaa tgccataacg agtgggaaat cacattcgag gagattcacc
    56521 gaaatggcgc gattgcctat gcaatctaca attatacgaa ttacaccggc gatacggaat
    56581 atttgaaaaa tgaaggactg gaagttttag cagaaatcgc acgcttctgg gcagaccgtg
    56641 tccatttttc aaaacgagca aataaataca tgatccacgg tgtgaccggc ccaaacgaat
    56701 atgagaacaa tatcaataac aattggtata caaatacgat cgcagcttgg gtcttgcgtt
    56761 acacgcgaga aaattattta acttatcaaa aagaagctgc tatcactatc agcgaagaag
    56821 aactagccaa atggaaagat atcgcagaga acatgtactt cccagttgac gaagaattag
    56881 gaatctttgt ccagcatgac acattcttag ataaagatct catgcctgta tccgatattc
    56941 ccacaagcga tcttcctctg aatcagcatt ggtcttggga caaaatcctt agatcttgct
    57001 tcatcaagca ggcagatgta ctacagggga tttatttctt caatgatact tttacaaaag
    57061 aagaaaagca aaaaaacttt gatttctatg aaccaatgac tgtccatgag tcttcccttt
    57121 cgccaagtat ccattcgatt ttagcagcag aattaggaat ggaaagcaaa gctgtagaaa
    57181 tgtaccagcg aacagctcgc ttggatttgg ataattacaa taacgacaca gaagacggct
    57241 tgcacatcac ttccatgact ggtagctggt tgtcgattgt ccaaggattt gctcaaatga
    57301 aaactaccca tgatcagttg agattcgcac catttctgcc aaaaacttgg aaagcttatt
    57361 ctttccatat caattatcgc ggacgtttat tgttcatctc agtcacagat gaacaagtta
    57421 ctttcgagtt attagaaggt tctcctctag aaatttacgt ctatgaacag tcttattctt
    57481 tagcggatcg tctagaaata acgctaagaa aggaggaagc aaatgtttaa aggggtattg
    57541 tttgatttag acggtgtcat taccgatact gctgaattcc attatcgtgc ttggcgaaag
    57601 cttggtcagg aaatcggcat tacgatcgac cacacattca acgaacagct aaaaggcgtc
    57661 agccgagaag actcactctc tttgctttta gcttatggcg gaaaagaaca ctctttttca
    57721 aaggaagaat ttgcagaatt agcgaaaaga aaaaacgatt attatttaga gatgatccag
    57781 acgatcgaac caaaagatgt cttccccggg gtcgtgcctt tactggattc tttaaaagaa
    57841 gaaaaaatca agattgctct tgcttctgca agtaaaaacg ggccattcct acttgaaaaa
    57901 atgggtctta caccttactt tgatgctatt gccgacccgg cagaagcaac aaacggaaaa
    57961 cctgcgccag atatcttcct ccttgcagca aaagctgtcg gactaaaagc agaagaatgt
    58021 atcgggatcg aagacgcgca agccggtatc caagccatcc tctcaagtgg cgctcaacca
    58081 attggcgtgg gacgtgctga agaccttgga gaggagatcc cgcttgtccc tgatacgact
    58141 tttcttacga tcgattactt gaaagaaaag tggcatgacc atggataatc cagagatctc
    58201 cgtcgtacca gttccagaga ctgaaataaa gaaaatcaca ttgaagaacg actacttaga
    58261 agtcgttctt ctcaattacg gtgcccgcct gcaccaaatc ttcgcaccag acaaagaagg
    58321 aaaatcagaa aatgttttat tgtcttacga tcgtttcgaa gatgttctaa cagacaaaag
    58381 cttttttgga gcaactgtcg gacctgtagc cggaaggatc cgggatgctt cttggggtga
    58441 gcatagattg gagaaaaact gcggatcaca ccatatccac ggtggcacga aaggctggtc
    58501 tttccaattt tgggaagtag aagttttcaa aactccatca tcaataggtg tggtctttta
    58561 cttaaaagat gaattttcta cctatccagg accaatcact gctacgatca cttaccgttt
    58621 aacaaaaaac gaattagaga tgacaacctc tgctagtagc cttgttgaaa ccatctgcaa
    58681 tccgaccaac catgcctact tcaacctttc aggaaatgga acaagagaca tctatgaaca
    58741 tcagttaacg gtctttttag atggtgtgct tgaattagat caagaaaaac tgcctactgg
    58801 aaattggaca aaaaaagaaa aactgccaat cgactttaga aaatccccaa cactgcaaga
    58861 gatccttgca tgttatccag atggactaga tgatgtattt cttttgcatc atcctaggct
    58921 ttccaaaact tccttacaat tattcgagaa gcattctggt cgccaaatga ctatagcaac
    58981 ttctaataaa agtatggtat tattttctac gactggattc gaagctgatt tctctgtcaa
    59041 tggaaaacag atgcattcaa actacggatt agcaatcgaa ccgcaagaaa tccctgatat
    59101 cgttcatttc cccaaatttg gatcgatcaa cctccatcct ggtcaagaac ggatcagtca
    59161 gacgatttat cggttctctg cacaataaca agagaaaggt gtttttatca tggctattac
    59221 cgtaaaagat gtggcgaaaa aagccggtgt tgccacctcg accgtctctc gtgtcatcaa
    59281 cgatcatcct agtatttccg agacaacaaa gaagaaagtc cgaaaaatta tggatgaact
    59341 aggttatgtt cctaacatga ctgcccgcaa tctaggaaaa cgcatttcca gtgccatcgg
    59401 cgtaatctta ccccctcttg attcaaaaga gcggatcggt aacccatttt atcttgagat
    59461 catggaagca atcaacgaag aagcgcggaa ttatgatatg actacagcaa tcgctactgc
    59521 taaaaatttt gaattgctgt tagagaacgt ccagcgtatg catttacaaa aacaagtaga
    59581 tggttttatt ctagtgtatt cagatagtca agatactgtc attgattatt tataccaaaa
    59641 ccacatccct ttcactttga tcggacagcc ttatcatcat gagaacgaaa tcgtttatgt
    59701 agataatgat aaccagcttc taggtaaaca agcaacagaa tttttgatcc agaatggaca
    59761 taagaatatc ctgtttgtga caaacacgac tcatgaaagt ttgtatttcg aacgatattt
    59821 cggttatcaa aaagcaatga tgatggctgg tcttcctgcg ttatccagtg tagtactaga
    59881 gcatccggag gattatctgt cctttgagaa aacgttgaaa gaaaacgaag ccacagcatt
    59941 ggtggtcatt gacgatatct tcgcccttcg cacgatgcag ttggcgcaaa tgtatggcta
    60001 tgtcattcca gagacactct ccgtcattag cttcaacaac tcgatcttct caacattaac
    60061 acacccttac cttacaagta tcgatatcga tatctccgaa ttaggacgtg tcgctatgca
    60121 aaagctgcgc gaattgatcc atgaagaatt gagcagtggc gtacgtttgg tcatccctca
    60181 tcgcttgatc aaaagagaga cagtcgttcc tttagaaaac ccatactaaa tagctgactc
    60241 actaaatacg ctgaccattt atcctatggt cagcttttta tgtaaaagaa gatactactt
    60301 ctaacacatt gtttatctgt aaaaaagagc gtgggacaaa agtaaagaac acttttgtct
    60361 cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa
    60421 attcacaaaa atttaaaaag caattttctt gagtttcttc ttatttcttg gagttaaacg
    60481 cttctgtccc agcctctttt ttccttcctt caatttttta cacgtcgacg attcaataaa
    60541 aaaccgccta atattgtaaa gacaggtgca agaatcgaga aaaaggcgaa tggcaagtaa
    60601 tgcaacgcgc taactttcat cgttcccata atgaatgtgc cgctgactcc ccacggtacg
    60661 agagaattga cggtcgcacc tgaatccgct agtgttcgtg tcaaataggt ttttgataag
    60721 ccaacgtcat caaaagaacg cttgaatgtt tctcctggaa gaatgatgga cagatactgt
    60781 tctccaacga tcagattgat tccgatacag ctcaaggcag taaacccgac taaacgagaa
    60841 ggtcggtcca tcttttcttt taattcttga acgatggtat caacgatcag atatttgatc
    60901 agtaacccac ctaatgccaa tgcaagtaaa atcaaactag cagaacctaa catactcatg
    60961 atcccgcctc gagaaagcag ttcatctagc tttggatcag gtgtatttgc gacataacca
    61021 ttcatcaaga tgtctgctgc ttttccgacc gtcaaacttt tctcatggat aaaagaaaga
    61081 acgagagcag ctgtcgatcc cgctagtaat gtagggatag ccggaatttt tttgattgcc
    61141 cccccaaata aaataactag tggaatcaat gtccaaggag agatccaaaa gctcgctttc
    61201 atgttttgga tcatttcatt gatactagct agatcggctg aatgactgtt atgtcctaat
    61261 atcgtataaa aaatcaacga aaggacgaat gctgggaaat ccgtataacg cataccagcg
    61321 atatgttcga atagattaac tcctccaata cccgctgcca agttggtcgt atctgataaa
    61381 ggcgagcagt tattccctaa aaaggcaccg gaaacgactg cgcctgtagt cattgcatca
    61441 ttgaatccaa gtaaatgacc gatccccaaa aaagcaattc caatcgtcga aatcgttgta
    61501 aatgaactgc cgacagtcac tccgacaatt gcacaaacaa gaaatgctgt cggtaaaaag
    61561 aaacgcacag aaacaagttt aaatccataa accataatcg tagggatggt tccagataaa
    61621 atccatgaag caactaagac accaatcaaa agaaaaatca ggattggaat gatccctgga
    61681 gtgattcctt tgatgatccc gtcatggatc tcatcccatg tgaacttttt aaatctgcca
    61741 taaaacaaca aacacatgaa agctgcaagg atcgggatat gtggcgagag ctggaatccg
    61801 atgatcagta ctcctaggag tgccaacaac acgatcaata cagcgatact ttcttttaaa
    61861 gaaatatttt tattcatcgt cgatctccta tttcaaatga aaaggccctg ccatgaaaaa
    61921 actattcact tggcaggacc tcctactaaa tcagcgacaa aacgtcggct gaaagactta
    61981 tttttttatt tttcttctaa acttttttct acctcaatcc cccaagaatc tttcttgaag
    62041 tgattgatga tcaatggaat aacgaacatg accactgtga tagctgctac taataatgca
    62101 tcactcaatg tcgctgtacc taatgtagca aatacgacaa cgatgataga gaagatcagc
    62161 atgcagctga ctacccaagc taatccgttt ccgtttttac caattcggta aggacgttcg
    62221 aattctggat gtttcttacg cattttaagc aatgaaacag caatcaaaat gtacacgata
    62281 caataaataa cagttgtagc atttgtaagt gtcaagaata cagcacttac gtcatccatt
    62341 acaccataaa gcaaagcaaa taatgaaata acgattgatt gtgttagaac gacatttcta
    62401 gatacgccgt atttgttttc tttatggaat ccgaattttg gtggaaggaa tccttcacga
    62461 gctacttgga tgattgtttt tgatggtcca gtaacccaag ctgataattg taaaagcaca
    62521 ccaataaata ccatgaagct gaagatattt ccgatcactt ctggtaagcc taggatttga
    62581 cagtcaatca agataggctg cgtgatattt gctaattcca tttttccatc tggtacgaca
    62641 tttgctacaa gcatcgcatt gatgacattc aataaaacta atccgatcaa agcgataaat
    62701 acgccttttg tataattttt tgttgcgtct ttcaaacgag gcatgtaaac agaactcatt
    62761 tcgatcccaa caaaaataaa tgtgatacca gctaagtatt tcaatgaatc aatatgttcc
    62821 aagtcaggga aagcttttga ccatgaaaag tcacctagat agccgtttga gactagtccg
    62881 actttgaagg ctgccaaaac acctaaaacg aacatgatga ctactgggat atatacccct
    62941 agccatacac cgatgttccc gccgactttt gccatatcga atttcaagtt caagatcgtg
    63001 atgatccagt agataactaa aatacaacct aaaacgaacc agtgattatt gccaagttct
    63061 acattaccaa atgtgtttcc taacaatggt cctaaagtag aagcgaccat taccatacct
    63121 gggaacattt gcacccataa tagccatgca acgacaaatc cccatttgct gcccagtgct
    63181 gtttttaccc ataactgagg accgccttct tgaggaagca tcgtggaaag ctcaccggaa
    63241 accattgata tcggaccggc aaaaaacaaa actgcaaaaa ttgaataaaa aatcaatgtc
    63301 caaccgactg cggctaacgt aggaatactc cgaaccgttg cacacagtgc cattgtcaga
    63361 ccgataaagg tcccaagacc cattttactt acttcagatt tactcaccgt tgacactctc
    63421 cttgattttt tggataaaat aacggtgtct ttgaagtagt ttcagcaata aacgaaacaa
    63481 ttcagcgaat atttgagggg attctttgag tttattgctt gaagggtttc ttcaaagaca
    63541 acctcaaaac aaagggatcg aagagcttag gtctcccctt gctcttcaga tccaaacatg
    63601 cgtcagaaac agttagtatt caagctgttt tctaacatga ttaccttgct tattttgctt
    63661 cgcttgccaa taattggtct gcgtagattt tttccaattt ttcttgaaga gctgctttga
    63721 ttttttcagc atattcttca aagtgttctt ctttgttcat gtatggtgtc attacgctgg
    63781 cacgcaatac agttactttt ccggcacggt tccattcttc atctgagaat cctagttggt
    63841 tcacaaattg taatgggctg ttgccatagt ctgggatagc aaagtcagta tgtgaagtta
    63901 agaactcatt accgtaaatg cttcctttca cgtatgaaga ataatcatat acgtcatggt
    63961 tcaatttatt cattgcaact aagtcatcgt tgcctttttc tttgaataca tagtctacca
    64021 tattgaaatc tggataagtt aatggatgaa cttcgatttc tttgtctcct actttaaatg
    64081 acaagtcatt caagaagttg tagaaacgat gtgcaccttc gattgatgca cccattaatt
    64141 taccatatcc tgtgacattc aaaggtaaga catggtgtgc tgcccaaacg ctggctgctg
    64201 ttgcccctgc ttttgaacct tccaagatat aagccccaag taatgctggg atatctgcgc
    64261 ctttttcaaa tacatatgtc gcaaagtaag agataacgtc tctcatgcgg atatctttga
    64321 tgacgatacc accggcagaa tatggaacat agcccatttt atgtgggtca atcgttacag
    64381 attctgcttc ttcgattgct ttatatgcac tgtgtacttc ttctaagata taatctttgt
    64441 tttctgtaaa gacattgtat ttgtaatgaa catcttttaa atcttcaaat ggaatgaagt
    64501 tgttgtcttc gtctaagaaa atcgcacggc cgtatccgcc ataagcagca tctacgtgta
    64561 agtagaagta aataccgtct ttttctaata cgcgacgcaa tgcaacgatt ttatcgatac
    64621 cgtcgattgc tccttcttct gttgatccta caacaccgac tacacctagg attggtgttt
    64681 tttcagctgc tagaccacga acgatttttt caagttcgtt gatgtccatg cgatagttgt
    64741 ggtcaactgg cactggaatc acttggtcta aaccgatacc gatgatgtcg gcagctttta
    64801 gccatgaata gtgtttagtt tgtggaacca accattttcc taatttttct aaatgttttc
    64861 cgctacgtgc tgagtgagct ttgatttcgt cgattttttc tgggacgctg tctaacagat
    64921 tcatgatttc ttctgttgac aagttcatta attcccaatc gctttttcca gcaactagtt
    64981 caggtgtcac ttctttcatt gcaagcggca atgatttgat gttgcgggca taccaaagtc
    65041 cttctaagtt tgctaaagaa ccatcagcaa cgatgtggcc ccagccatct ttatagctca
    65101 ttaattttgc aaattccatt cctacttctt cttccatttg gcttgttgca ggagaagatt
    65161 cataggcaac gttattacca ttccatagca tagcaaaatt gtacgctagt aaagatggca
    65221 tcaatgtttc agagttcata tgaccccagt aacgtccggc attatgccaa ggaacggaat
    65281 gggtacgcat ccgcgctgaa atttctgata gaacatcctt tgttttattc acagtgtgtt
    65341 caaaactagc actgcttttt tcttctggcg taataatagg catgtcttga ggcatgtagt
    65401 tttgacgcca gcctaaatgt tcatccacca attcattcaa caaagcttta tagatttggc
    65461 cgttctcagc tttgtcccca atgaataggg catttaggtt tagatctttc gacaatgatt
    65521 cactcatagt gaaaccctcc taaaaaaata tttaaatttt gtcgagccct acattacacc
    65581 tgttcttcta ttctgtaaac taagttttgg cctgattttt aatcatattt taatatgtat
    65641 caattatccg aattgttcac acttttgaaa taattaaaaa aaacgaggga atttacaaat
    65701 gtaaactccc tcgcaaagat tgtattaacg acaaccagcg ttctatttta ggatgggttt
    65761 caaaattgga atgttgtaat agtatttccc ttttttaagg taaaaactta ctaaattcta
    65821 atcaattact ttggccaaaa agtaattttt cttacctttt cgaataacca caaacttacc
    65881 atcgaattca tcggatggat ttatgacaaa atttaaatcg gtaacgcggt caccgttaat
    65941 acttatagct ccgtttgaaa catcttcacg tgcttgacgt ttagatggtt caatttttgt
    66001 ggaaacaagc agttccacga tattttcagg tgtgcttgaa atttcaacgt tcggcatttt
    66061 accgaatcct tgcgcgattt cttccgcatt tagttcttta atatttccag agaacaatgc
    66121 ttgcgttatt ttttgcgctt ctttcaagtc ttcttcacta tgcacaaatc ttgtaacttc
    66181 ttctgccaaa cggcgttgtg cttcacgttt ctcaggttct gtctctactt ttttcgctaa
    66241 gtcttcgatt tcttcttgag acaagaaagt aaagaatttc aagtatttca ctacatcgcg
    66301 atcatcttga ttcaaccaga attggtagaa ctcaaatggt gaagttttct tcggatcaag
    66361 ccaaacggca ccgcctgcag tttttccgaa tttcgttccg tcagccttca gcatcaatgg
    66421 gatcgttaaa ccgaacgctt ctgcttctgg tccttctaat tttcggatta ggtctaatcc
    66481 agctgtgata tttccccatt ggtctgctcc accgatttgc aattgcacat cgtatgtttt
    66541 atgcagatgc aaaaagtcga tagattgcag gatttggtaa gtaaactctg taaatgagat
    66601 tcctacttcc aaacggctgg caacgatatc ttttgctaac atcgtgttga tgttgaagtt
    66661 tttaccgtag tctctcaaaa attcaagtaa agagattttt gacaaccagt cgtagttgtt
    66721 cacaaatgtg atatttgcat ctttaccaaa caattttctc atttgattgg aaagtgcgtc
    66781 cacgttatgt tgcacttgtt ccatcgtttg caacacacgt tctgttttgc ggccgcttgg
    66841 gtcgccgatc gttcctgttc cgccgccaat cagaatatat ggatgatggc ctgccaattg
    66901 gaatcttttc atcatcataa atggaatcaa atgtccgata tgcatcgaat caccagttgg
    66961 atcaacgccg caataaagtg aaatgctctt ttcttcaacg agctcgcgaa gtctttcttc
    67021 gtttgtttgc tgattaatgg cgtcgcgcca agttaattca tcaataatat tcattttact
    67081 gacctccgtg tagttttttt atgaaagcag gaacctgcta gcatatgtaa ttaattattt
    67141 cttcaggata ggataggaaa taaaaaaagt cccttggcat ataagccaag ggacgaaatc
    67201 tcgcggtacc acccaatttg tatgtctaga tatccaacat acctctcgaa catttaacgc
    67261 tgtcgcgtgg caatcactgc caaagactcc tgaaatgtaa ttcgctttaa agcatgtact
    67321 ggtttgcagc gaccaccagc tttctgaaac attggcttta acaactactt cgtttcgatc
    67381 ttcgtcttgt tattattaat atgtgtctat catagagcgc aactttttct ttgtcaacag
    67441 aaaaaggata ttttttttaa attcctcatt ttttcttttt tgaatccgct ctaattccga
    67501 acattttatt ttcaattatt gttaaaagaa ataacttttt ctgtattttt tctgcaattt
    67561 atcgagaagt cactttactt tgcctcttat tctttcttcg ttacaataag gaatgggaca
    67621 agtaaaaaaa tgaaaaagca agggacgagg tatatggaaa aaaagcaaaa aattatttta
    67681 ggagccactt ctgctttaac tatcgttatt ttaattctaa gtttgttttt tgtcatccga
    67741 tcatctacaa aaaaagaacc aatcattcct gaaaaaaaaa taacagaaaa agcaaaagaa
    67801 ccgacagatg ataagcaaca actagttact caagcaaaaa atctggctca aagctacgat
    67861 tatgaccaag cgattgcgtt attggaaaaa gatagtaaga acggatctac tgaaacacaa
    67921 cagcttcttc aaacactaaa aaaggagaaa gaacaactga tcgactggtc tgatcctact
    67981 cagatctctc atgtcttttt ccacagcttg atcgtggacc cgcaaaaagc cttccactct
    68041 caacaggcac aaggatacaa agattatatg gtgactgttg aagaattcaa ccgttcgatc
    68101 gaacaacttt atcaaaatga ttttgtttta gttaatttga atgatttgat ccaaaaagac
    68161 gaacaaggaa atctttcctt taacgggctt gcgctacctg aaggaaaaaa accattggtt
    68221 ctttcacaag atgatgtcag ctattatgaa tatatggata attccggttt tcctagccga
    68281 ttggtcgtat caaataacaa tgaaatcaaa aatgtctata aagagaaaga taaagaagaa
    68341 atcggtgact ttgacatggt tcctctgatc gatgcctttg tcaagaaaca tcctgatttt
    68401 tcttatcgag gcgcaaaagg taccttggcc ctgacaggtt acaacggagt tttaggttat
    68461 cgaacatcaa aatctcaata tggagacaat gaaaaaacaa aaaaagagat taaagaagct
    68521 aaaaaagtgg cggaacagtt gaagaaagac ggctggagct ttgcttccca tacatggggt
    68581 cacttgaata tgactcaagc ttcactagaa gatgtaaaaa aagacaatga attgtggcag
    68641 caagaagttg cacctatcct aggaaaaaca aatattctga tttatccatt tggtgcagac
    68701 atcagcgact ggcagcctta ttcagcagaa aatcaaaaat ttgcttactt gaagagtcaa
    68761 ggtttcgata ttttctgtaa tgtcgatgct tctacaccag cttggggaca attaggtacg
    68821 gatttctatc gaaatgctcg gatcaatatc gatggcattc gttttcaatc tgatttagac
    68881 ggaaaaaatc ctattcttga tccattcatc aatgtccatg atgtctatga caaagaagca
    68941 cgcgaatctg cttgatttta cgtcatttat gaaccaaaaa agccgaactg acattttatc
    69001 gtcagtttcg gcttttttat gctttatttc ttcttcggtg cgattccctt gatcaggact
    69061 tctgtccatt ctgctgtata tggaagcagt tttgcgtata tctccggctt agaaattcct
    69121 tctaccattg cttgaaaata gaggatcaag aactcatccg aatatttcaa atccactttt
    69181 ccttctttcc gccctcgatg gaaaagatca agcatgatac tgaaactttc ttgcgtatac
    69241 gcatccatcg cgtcagaaaa ttcttttttt tctttttttg tatagtatgt catcaaatcg
    69301 atataaaatt gtttgttcac tcgattgaga taacggattt tgttttcact catggcaatc
    69361 agtgtttctt caaatggaag attttccgca atcaacgctt tcgcttcttg ccctaaatca
    69421 ttcataaatg caaaaaatac ttcataaatc agcccttcct tgctgccaaa atatttaaaa
    69481 atcgtcgctt tacttacctg agcgttctca gctaccttat ccattgtcac tccagcggtt
    69541 cctatgtctg tgttcatcaa gtcaaaagct gcttgtaaaa tctctttctt tttctcttgt
    69601 gctctctttt caaaaccgtt catttgtaga gcctcccgta attttaaact tttataatat
    69661 gtatagttca aatttattct gaggtttatt ataactatct attgagaaag tatcaagcta
    69721 gcaattcctt gtttatgaat tcattgacag aaatttataa aaagaatatt atgtactaaa
    69781 ataataaaaa aagttttata aaaaggtata aaaccttttt attaaactat ttaatcttgt
    69841 ttagtatata tttttagaaa aaggagtggg gtttttatgg cagaaatcgt caaagtcaca
    69901 catttgaaaa agagctttgg tcgtttcgaa gctttaaaag atgtctcttt caccgtacat
    69961 tcaggtgaag tcgttggatt tatcggacca aatggttctg gaaaatccac gacgattcgg
    70021 acacttttag ggattataaa aaaagacggc ggaacggcaa cgatttttgg gcaagatgta
    70081 tgggaagata gtttatctat ccatgaacgt ctttcttatg ttccaggcga tatctctttg
    70141 tggggaaatt tgactggagg agcgatcatc gatctcttca tgaagcttca tggaaaaggg
    70201 agtgctcaaa aaaaagatga actgattcaa cgtttctctc ttgatcctaa gaaaaaagca
    70261 aaaaactatt caaaaggaaa tcgccaaaaa gtgggcttga ttgctgcttt ggctgttgat
    70321 tcggatctct atttatttga tgagcctact tctggtttag atcctttgat ggaaacgatt
    70381 ttccaagaag aagttgaaaa attgaaagaa cagggcaaat ccatcctact ttcttctcat
    70441 attctcagtg aagtcgagcg actagcggat aaagtcgtga tcatacgcga aggaacactc
    70501 gatgaagaag gaacactcga tgaattgcgt catttgactc gttcgaccat cactatagaa
    70561 acagaagcag agaatagtca cttagcacaa ttgaacggtg tccatgactt tgtgcaaaaa
    70621 ggtcacctcg ctcaatttgc tgctgataac gaagctttcg atgtgatttt agctgaagcg
    70681 tccaaattag gtgtgaaaaa atttgaatct attccaccga ctcttgagga tttattcatg
    70741 agacattatg aaggatgagg aggaagcgaa atgactgata aattttcacg ctggtccacc
    70801 cttttttctc aaaaccttag ccgtgactgg aaaaagatcc tgatatggct agtcggtgtc
    70861 actgcttttt ctggtggttt tgtccctgcg tttgaagaat tgacttccgg acaaggatta
    70921 gctggattat acgaaacctt gcaaaacccg gcaatgattg caatggtcgg accaactcca
    70981 gcttcgaatg ctgctgagta tactttagga gcgatgtatg caaatgaaat gttgcttttt
    71041 tgcagtttgt ttgctgctgt gatctctgtt ttacacgtgg tgagccaaac gagaaaaaaa
    71101 gaagaacttg gtctgattga acttattcgt tcctttcgag tcggacgtca agcaaactct
    71161 ttagctgtca tcgctgaaag tattctgatc aatttgcttt tagcaatatc gatcagctgt
    71221 acgatgattt ttttccaagc ggattcgatc actgcagaag gtgcttggct ttttgggcta
    71281 tctgtaggta gtatggggat tttggggagt gccgttgcac tgtttgctgc acaactgatg
    71341 ccaagttcag ccagttcgaa tggtctgtct ttagcgtttt taggtggact ttaccttcta
    71401 cgagcaataa cagatgtagc tgattcctcc ctttcgatgt ggaatccttt aggctggtct
    71461 tatttgacct atccatttac aactaacaac tggattcctt tgctttattt gtttttgttc
    71521 agtctaatct tgataatcag ttcatttgtt ttagaggaac atcgagattt gaacaccggc
    71581 tatatccccg aacgtgaagg aaaaccgtat gctaaacgtt ctcttttatc cttgcgtggt
    71641 ttattattct atctaaataa agggatgaca atcagttggc ttatcacttt tggtttgatg
    71701 ggggcggcat acggctctat ctacgggaat atgcaacagt ttttagaaag taacgactta
    71761 atgaaacaga tgtttatcca atctggcgtc tcaattgaaa aaaactttac aagcacgatc
    71821 atggtagtct tgatttgtct agctgctatt ttaccaattg ctagcatcaa tcgtttattt
    71881 acagaagaaa cccacggacg tatgaatcag ctgttcgcaa caaaaatttc taggaaccaa
    71941 ctttattgga ccaatatgtt actagctatt ctatttgcta tattggcaat cctgattagt
    72001 tctggtgcac tagggctttc tgctttggct tcgatgaagg atgcgaaaga catggatcta
    72061 ttgatgtttc ttaaagccgg gttcaatttc ctgcctgccg ttttagtgtt tatcggaatt
    72121 agtggctttc tattcggatg gcttcctcga atcggtaaac ttgcttatat ctacttagct
    72181 tactcctttg cactcaatta ctttggcgga attttggatt taccagaatg gttttccaaa
    72241 acagctgtcc ctagctgggt tccacggatg ccaaacgatt cttttgatct ttccgtgttc
    72301 cttacgttat catgtatcag ccttgcactg ttcgtccttg gttctattgg ttataggcga
    72361 agagacttac tagaaggata ataaaaaagc atgtacaatt tcatgctagc ctccaaatct
    72421 gggtcaaaaa tccaacattt ggaggtcatt tttttattta caagtcttct aactgctctt
    72481 tatcaatgat ccagacttct cgattctttc tttttacata accattctcc tctaataatt
    72541 taaattttct agataaagtt tcgggggtcg taccgataaa tgcagcaagt tctttcattt
    72601 tcattggcag gaaaaagtga tccttccctg tcgctttagc taagtcaagc agatagacag
    72661 cgactcgttc ttctactttt tccatcatca aaaaagttgt ctgctgctgt acttttgtta
    72721 atttctcaac gttgattgct aaaagtttca gactaagggc gggataatgc agtaagagtt
    72781 ccgagaaatc tttttgtctc aatatgcaaa tttccgtttt ttctagtgct tcgccaaata
    72841 aagactcatt tggaacgcct agcaactggc tctctccctc atatccgccc ggctctatta
    72901 ctcgtaaaag ctgttccttt ccgctagcag ataattgata cactttcata ctgccggagg
    72961 ccacgatcac taattgaggt tctccattcg gcgcaagaat ctgttctcct ttttccacat
    73021 agtgatgttt gacaagtgcg tgtacttttt cttgatcttg ctgtactaag tgattgaaca
    73081 aaggaacaaa tgaaacacat aaatgatcat gactcataat ctctcctcct tctaaacagc
    73141 tatttctaat aaagaaacat aacttccctt attccaactg ataattttct tttatcatag
    73201 cataaacgtc aagcgaacca gataccagca aatagagtgg atttcttttt gtcccttgct
    73261 ttattttcct tcttttgaga ccttaagtaa ttgattccta tcaatttttt aaatatttac
    73321 tttttgaata atcaaaaaca aaccttcact cgcaagccga gagtaaggtt tgtttttcgc
    73381 attgcttatt tcgtgttgtc tattgaaatt tttccgcacc tagcttttga tatagtggtg
    73441 ctagttcttg taaggtttca gcggttattt gctcaacgtg ttcgatttct tgcggataga
    73501 agaatagttt acccatttga aaggttcggt ctctcatcgc ttttttcaac tcttcttgtt
    73561 tctttgtatc ggacaaatag tcagacaaag ctaagtggtc gtcaagttca tgttctggtt
    73621 gcggccatat gtaataatcc ttgatatcga ctgttttgct ccactctttc agtatcgcaa
    73681 gcaactggtt atacgctgca atgctaccat atcgttcttc gcttttataa tgttggtaca
    73741 tcaaatagat ttggtattgt ttttgattca acaaaactgc tagacaggca ttctcgtctt
    73801 gacgagattc gcttcggtac gcgctccaaa aatgactgcg taaattccag ccattcgtcc
    73861 agctttcgat tttaggtttg ctcatgccgt acatatcagg caaaagtgca gctgtctgga
    73921 gctgaatctc tttccatttt tgccagtgtt ctttatattc tttcttgatt tgttcaatct
    73981 tatctgttgg atggctctct ttgagctgtt tgaatgcgta gattggtcga tcaaacaact
    74041 gataatctga ttttccaagt tccattgttt cgcctctttc cgttatcttt tgtattctac
    74101 ctgaattttg cgatatggac aaatagaggt tgtgaaaaag ctgttctgca tcaagtcata
    74161 agaacagcca aacaaaaaac tgcgatgagc atcaccgcag tttt
//
LOCUS       DAIGTA010000004        73756 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.004, whole genome shotgun sequence.
ACCESSION   DAIGTA010000004 DAIGTA010000000
VERSION     DAIGTA010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.004"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(225..941)
                     /locus_tag="NOB43_000254"
     CDS             complement(225..941)
                     /locus_tag="NOB43_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI0981163.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(942..2765)
                     /gene="glpO"
                     /locus_tag="NOB43_000255"
     CDS             complement(942..2765)
                     /gene="glpO"
                     /locus_tag="NOB43_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HCI0981164.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(2779..4275)
                     /gene="glpK"
                     /locus_tag="NOB43_000256"
     CDS             complement(2779..4275)
                     /gene="glpK"
                     /locus_tag="NOB43_000256"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCI0981165.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(4411..5871)
                     /locus_tag="NOB43_000257"
     CDS             complement(4411..5871)
                     /locus_tag="NOB43_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0981166.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(5861..7156)
                     /locus_tag="NOB43_000258"
     CDS             complement(5861..7156)
                     /locus_tag="NOB43_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0981167.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(7488..8165)
                     /locus_tag="NOB43_000259"
     CDS             complement(7488..8165)
                     /locus_tag="NOB43_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HCI0981168.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(8195..9286)
                     /locus_tag="NOB43_000260"
     CDS             complement(8195..9286)
                     /locus_tag="NOB43_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HCI0981169.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(9387..9821)
                     /locus_tag="NOB43_000261"
     CDS             complement(9387..9821)
                     /locus_tag="NOB43_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0981170.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(10405..11862)
                     /gene="ascB"
                     /locus_tag="NOB43_000262"
     CDS             complement(10405..11862)
                     /gene="ascB"
                     /locus_tag="NOB43_000262"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0981171.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(11859..13754)
                     /locus_tag="NOB43_000263"
     CDS             complement(11859..13754)
                     /locus_tag="NOB43_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0981172.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(13812..15587)
                     /locus_tag="NOB43_000264"
     CDS             complement(13812..15587)
                     /locus_tag="NOB43_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI0981173.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(15637..17133)
                     /locus_tag="NOB43_000265"
     CDS             complement(15637..17133)
                     /locus_tag="NOB43_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0981174.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(17327..18949)
                     /locus_tag="NOB43_000266"
     CDS             complement(17327..18949)
                     /locus_tag="NOB43_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI0981175.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(19277..20590)
                     /locus_tag="NOB43_000267"
     CDS             complement(19277..20590)
                     /locus_tag="NOB43_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI0981176.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(20871..21059)
                     /locus_tag="NOB43_000268"
     CDS             complement(20871..21059)
                     /locus_tag="NOB43_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981177.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKE"
     gene            complement(21079..21501)
                     /locus_tag="NOB43_000269"
     CDS             complement(21079..21501)
                     /locus_tag="NOB43_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HCI0981178.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(21646..22356)
                     /locus_tag="NOB43_000270"
     CDS             complement(21646..22356)
                     /locus_tag="NOB43_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981179.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(22374..22871)
                     /locus_tag="NOB43_000271"
     CDS             complement(22374..22871)
                     /locus_tag="NOB43_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0981180.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPKHLADYLTQAYAPEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(22908..23360)
                     /locus_tag="NOB43_000272"
     CDS             complement(22908..23360)
                     /locus_tag="NOB43_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0981181.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(23495..24100)
                     /locus_tag="NOB43_000273"
     CDS             complement(23495..24100)
                     /locus_tag="NOB43_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0981182.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(24655..25290)
                     /locus_tag="NOB43_000274"
     CDS             complement(24655..25290)
                     /locus_tag="NOB43_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCI0981183.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKKSMTISNKEMA"
     gene            complement(25292..26161)
                     /locus_tag="NOB43_000275"
     CDS             complement(25292..26161)
                     /locus_tag="NOB43_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HCI0981184.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYISMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(26184..26591)
                     /locus_tag="NOB43_000276"
     CDS             complement(26184..26591)
                     /locus_tag="NOB43_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI0981185.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELYENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRSD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(26610..27782)
                     /locus_tag="NOB43_000277"
     CDS             complement(26610..27782)
                     /locus_tag="NOB43_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI0981186.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAILWMATMTTVFGY
                     FAGLRGIVLILVGGFIGACFAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVA
                     KLFGEKGENKKSIEDIKLPTHFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGD
                     QNYIMFAFLQAIQFVVGVYVLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFP
                     YSPNAVILGFITTTIGTIIAMFTLPMFGLAMILSGMLTNFFAGGTAGIFGNAVGGRRG
                     AIIGGIAHGFFITLLPALLVTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(27809..28111)
                     /locus_tag="NOB43_000278"
     CDS             complement(27809..28111)
                     /locus_tag="NOB43_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0981187.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(28136..30222)
                     /locus_tag="NOB43_000279"
                     /pseudo
     CDS             complement(28136..30222)
                     /locus_tag="NOB43_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            complement(30711..31476)
                     /locus_tag="NOB43_000280"
                     /pseudo
     CDS             complement(30711..31476)
                     /locus_tag="NOB43_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
     gene            complement(31587..32456)
                     /gene="mdcB"
                     /locus_tag="NOB43_000281"
                     /pseudo
     CDS             complement(31587..32456)
                     /gene="mdcB"
                     /locus_tag="NOB43_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
     gene            complement(32481..33565)
                     /locus_tag="NOB43_000282"
                     /pseudo
     CDS             complement(32481..33565)
                     /locus_tag="NOB43_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
     gene            complement(33589..34182)
                     /locus_tag="NOB43_000283"
     CDS             complement(33589..34182)
                     /locus_tag="NOB43_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HCI0981188.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWATEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(34186..35862)
                     /gene="mdcD"
                     /locus_tag="NOB43_000284"
     CDS             complement(34186..35862)
                     /gene="mdcD"
                     /locus_tag="NOB43_000284"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HCI0981189.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDFIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEETIVISIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKFRQAGYPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(35852..36151)
                     /locus_tag="NOB43_000285"
     CDS             complement(35852..36151)
                     /locus_tag="NOB43_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HCI0981190.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(36253..37899)
                     /gene="mdcA"
                     /locus_tag="NOB43_000286"
     CDS             complement(36253..37899)
                     /gene="mdcA"
                     /locus_tag="NOB43_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HCI0981191.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVVADKADKDGNL
                     YTGFNTEETPTIVEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADEPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALVVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLREAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(37906..38817)
                     /locus_tag="NOB43_000287"
     CDS             complement(37906..38817)
                     /locus_tag="NOB43_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI0981192.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLTFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEMVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            38937..39227
                     /locus_tag="NOB43_000288"
     CDS             38937..39227
                     /locus_tag="NOB43_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0981193.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLYTLEEGINYCLRSMRRSLLPSYCI"
     gene            39179..39793
                     /locus_tag="NOB43_000289"
     CDS             39179..39793
                     /locus_tag="NOB43_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCI0981194.1"
                     /translation="MSSVNEKIVTSVILYLEVASVSIPNLVRIFMEKHPDIQLTIMQH
                     HLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPIL
                     MLSKSNAFRHTLDAALEAKSIELTISSTTDDPATLRSIVKQGLAVSFFPKVSWSYDKN
                     DPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAKTMREFYLGK"
     gene            complement(39980..40342)
                     /locus_tag="NOB43_000290"
     CDS             complement(39980..40342)
                     /locus_tag="NOB43_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCI0981195.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            40688..42125
                     /locus_tag="NOB43_000291"
                     /pseudo
     CDS             40688..42125
                     /locus_tag="NOB43_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(42132..44684)
                     /locus_tag="NOB43_000292"
                     /pseudo
     CDS             complement(42132..44684)
                     /locus_tag="NOB43_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(44798..46129)
                     /locus_tag="NOB43_000293"
     CDS             complement(44798..46129)
                     /locus_tag="NOB43_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0981196.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYSLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELAAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQMIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCTHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(46095..47573)
                     /locus_tag="NOB43_000294"
     CDS             complement(46095..47573)
                     /locus_tag="NOB43_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0981197.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPKKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(47878..49713)
                     /gene="tdc"
                     /locus_tag="NOB43_000295"
     CDS             complement(47878..49713)
                     /gene="tdc"
                     /locus_tag="NOB43_000295"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI0981198.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTTHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHMTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
     gene            50182..51609
                     /locus_tag="NOB43_000296"
     CDS             50182..51609
                     /locus_tag="NOB43_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0981199.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQVSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRLTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERTDRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(51701..52066)
                     /locus_tag="NOB43_000297"
     CDS             complement(51701..52066)
                     /locus_tag="NOB43_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI0981200.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQNDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(52063..52428)
                     /locus_tag="NOB43_000298"
     CDS             complement(52063..52428)
                     /locus_tag="NOB43_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI0981201.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(52620..52867)
                     /locus_tag="NOB43_000299"
                     /pseudo
     CDS             complement(52620..52867)
                     /locus_tag="NOB43_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            52866..52994
                     /locus_tag="NOB43_000300"
     CDS             52866..52994
                     /locus_tag="NOB43_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HCI0981202.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            53051..54745
                     /locus_tag="NOB43_000301"
     CDS             53051..54745
                     /locus_tag="NOB43_000301"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HCI0981203.1"
                     /translation="MRKSKSIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKSNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            54749..54868
                     /locus_tag="NOB43_000302"
                     /pseudo
     CDS             54749..54868
                     /locus_tag="NOB43_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            54872..54991
                     /locus_tag="NOB43_000303"
                     /pseudo
     CDS             54872..54991
                     /locus_tag="NOB43_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            55519..56652
                     /locus_tag="NOB43_000304"
     CDS             55519..56652
                     /locus_tag="NOB43_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HCI0981204.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNVLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            56683..56973
                     /locus_tag="NOB43_000305"
     CDS             56683..56973
                     /locus_tag="NOB43_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HCI0981205.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKQ"
     gene            complement(57033..57492)
                     /locus_tag="NOB43_000306"
                     /pseudo
     CDS             complement(57033..57492)
                     /locus_tag="NOB43_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(57622..58875)
                     /locus_tag="NOB43_000307"
     CDS             complement(57622..58875)
                     /locus_tag="NOB43_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0981206.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(58904..59221)
                     /locus_tag="NOB43_000308"
     CDS             complement(58904..59221)
                     /locus_tag="NOB43_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0981207.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(59247..59567)
                     /locus_tag="NOB43_000309"
     CDS             complement(59247..59567)
                     /locus_tag="NOB43_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0981208.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(60032..61447)
                     /locus_tag="NOB43_000310"
     CDS             complement(60032..61447)
                     /locus_tag="NOB43_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0981209.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREHEERYMDEKGIVQDDYRIEF
                     IGQHLRYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(61463..62779)
                     /locus_tag="NOB43_000311"
     CDS             complement(61463..62779)
                     /locus_tag="NOB43_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0981210.1"
                     /translation="MRGSGMSFMDKLAKVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISYLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(62929..63627)
                     /locus_tag="NOB43_000312"
     CDS             complement(62929..63627)
                     /locus_tag="NOB43_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCI0981211.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNIA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNVLAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(63916..64876)
                     /locus_tag="NOB43_000313"
                     /pseudo
     CDS             complement(63916..64876)
                     /locus_tag="NOB43_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            complement(64990..65823)
                     /gene="msrA"
                     /locus_tag="NOB43_000314"
     CDS             complement(64990..65823)
                     /gene="msrA"
                     /locus_tag="NOB43_000314"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0981212.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(66057..66800)
                     /gene="truA"
                     /locus_tag="NOB43_000315"
     CDS             complement(66057..66800)
                     /gene="truA"
                     /locus_tag="NOB43_000315"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI0981213.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            complement(66991..67626)
                     /locus_tag="NOB43_000316"
     CDS             complement(66991..67626)
                     /locus_tag="NOB43_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI0981214.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(67773..69014)
                     /gene="sstT"
                     /locus_tag="NOB43_000317"
     CDS             complement(67773..69014)
                     /gene="sstT"
                     /locus_tag="NOB43_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HCI0981215.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            complement(69335..70012)
                     /locus_tag="NOB43_000318"
     CDS             complement(69335..70012)
                     /locus_tag="NOB43_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCI0981216.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKNVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            complement(70263..70805)
                     /locus_tag="NOB43_000319"
     CDS             complement(70263..70805)
                     /locus_tag="NOB43_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI0981217.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(70810..71037)
                     /locus_tag="NOB43_000320"
     CDS             complement(70810..71037)
                     /locus_tag="NOB43_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0981218.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            complement(71116..72996)
                     /locus_tag="NOB43_000321"
     CDS             complement(71116..72996)
                     /locus_tag="NOB43_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI0981219.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            73282..73617
                     /locus_tag="NOB43_000322"
     CDS             73282..73617
                     /locus_tag="NOB43_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0981220.1"
                     /translation="MGIEAVDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLK
                     LLIHTACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECF
                     FIYDIIASK"
BASE COUNT        21789 a        15598 c        12353 g        24016 t
ORIGIN      
        1 aaaaagtcat gtcctatcct tattagaata caaagatatt gttttcctga caggtaccgt
       61 ttcataagca caccaaataa actttgttta ttggctattc gacttactga ttagatacca
      121 gctacactca caaaacatac cccattcttc taggtcttat ttattttcca cttaactata
      181 gcaagacaca ttttggttgt caaactttag tatgttttat agatttacac cattaatgaa
      241 tagacaccta ccgcgataat tgctccgatc attggacctg cgattggtac ccatgaatat
      301 gcccaatctg aagttccttt attagctatt ggcaataccg catgtgctaa tcgaggacca
      361 aagtcccgag cagggttgat tgcatatcct gttggccctc ctaatgaaag accgatggct
      421 aagatcaatc cacctacagc gaatacgttc gttccaggtg caaattcgtt ttgtccaaaa
      481 gctagcaacc caagaactaa tacaaatgta ccaattaatt ctgtgatcac atttgctgga
      541 taattccgta tagcaggacc tgttgcaaac gttcctaaaa tcgcgctttc atctttcgtt
      601 gcattccaat gtggcaaata agaaagccaa acaagaatgg cccctgcaaa agctcctaaa
      661 acttgcgcaa tgatgaaagg aacgacaaga ttccaactaa ttgcccctgt catcgccata
      721 gctagagaga ctgcaggatt caaatgagct gggcccatga atccagaaat atagacagcc
      781 attgttacag cgagtcccca accaaatgcg atgacaatcc agccagaagc ctgtgcttta
      841 cttttgttta aattcacagc cgcacacaca ccatctccaa gcaaaactag gatcagtgtc
      901 ccaataaact cccccatgat ttgagtcata tcactgttca tttatttctc cccctttagt
      961 tcccgcagat ctgattctgc aatcaatgct tctaaacgtt tagtctgttg cgccttctcc
     1021 tcttctgtcc attcaaaata tccagcaatt gcatcgatca caggttgctt gatctcatca
     1081 agctgatctc gttcaaacaa cagatgattt gtacgacgaa tgagataatc gcctggggcc
     1141 aaaaccattt cttcttctaa accataacgt aaccgagctg actcagcgag actcaaacca
     1201 ggataaggtg ccatttcttt tgctaattca aagatacgtc gggcattagt cccgtaaaaa
     1261 tcagcgatat aagtagcatc ttcttcctct aaaccggctg ctactccttc ttttgctaat
     1321 tctgtcactg tttcttctaa tttagttgga tcgaagtttc cacctgaaat ctgatatttt
     1381 ttagagtcga tttctttcgt ctctattccg tattcttctt ttaataattg gcgtatcaat
     1441 cgcaaagctc cttctgccat cttacggtaa tcggtgattt tcccaccaga taaagtcagc
     1501 aaaccatctg gttctctttc taaagaacta cctctggaaa tcgtagaagg tgctttttca
     1561 tcacggctgt tttccaaatg gttcaacacg tcttctactt cagcacgaga aactttgttt
     1621 tccttatatt cacttactgt atcgacaact ttattgaagc tcttgtctga aatcgatcca
     1681 ttatctccac cattgtaatc agaaccagaa ttaccaatca acagtggacg aagtcctgcc
     1741 cagcttgctt cgatatcatt caatgtgata tttgcttctg gatagcgatg attgatcaca
     1801 tccaatagat aatctacatc ttcttgtgtg actttcggat ccgtaaaatc tccttggtaa
     1861 tccgtatctg tcgtaccaaa gtaagtcttg ttttctcttg gaatagcaaa aaccatccgc
     1921 ccatcttgct ttcctgtatc gaagtatgtg ggttgcggta caggcagttt tttcgcatct
     1981 acaactaaat ggatcccttt agttggacgc attttaggag agactggacg cgtaaaattc
     2041 aagtttcgta ctttatctac ccaaggacca ctcgtattga tcactaattt tgctttgatt
     2101 tcgatcactt catctgtcag caggtcacga gctttgacgc caacgatttg atcgccatca
     2161 tataaaaagc caaccgcttt cattttactt actagataag ccccatcttc ggcagccttt
     2221 ttgatattat caatcactaa acgggcatca ttgttgcgga aatctagata gacacccgcg
     2281 ccttttagcc cttctttttt caaaaacggt tctctttcca atacttcttc tggtgtcagc
     2341 gtataattct catatttggt tcctgtcaca tttgccagtt tgtcataaag gtccattgct
     2401 actttgaccg agaacatatt gaaggttgtt gctccttcgc cctcatagat tggcaaaagc
     2461 attggatctg gttttgggat gtgtggggca atactttgta cgactgcacg ttcaccaact
     2521 gtgtcagcta ctacttccac atcaaatgtc ttcagataac gaataccgcc atgaacaagt
     2581 ttggtcgagc gagaggaagt cccttctgca aaatcctgca tttcgatcaa tcctgttttg
     2641 attcctgatg ctgctgactg gactgccaca ccggcaccag tgattccgcc accgatgatc
     2701 aacagatcca attcttcttg ctgcattttt tgaatgctat cttgtcttgt cttgtttgaa
     2761 aacatatgga tttcctcctt attcaaatgc ttgggtagct tttactgctt ttttccaacc
     2821 gttgtaaagt ttttctcggc gctcttcctc catttgaact tcaaatagct tgccagcttc
     2881 ataaaattcg cggatctcgt ctgtatcttt ccaataaccg acagctaatc ctgctaaaaa
     2941 tgctgcccct agcgccgttg tttccaagtt ttctgctcgt tggatcggta cattcaagat
     3001 atctgtttgg aattgcatca gatattcatt gtttgctgca ccgccatcta ctttcaatac
     3061 aggaatcttg attccagtgt catcttgcat cgtatcgatg atatctctca cttgataagc
     3121 aatcgactgt aaagtagctt taatgatatc ttcttttgtc gtaccacgtg tcaagccaaa
     3181 catagcccct cgtgctgcct gatcccaata aggagcacct agcccaacga atgcaggaac
     3241 aacataaacc tcatcttcgc ttgtagagcg tttcgctgcg tcttctgaat cgctagcttt
     3301 ttgcaacatt tgaagtccat ctctcagcca ttgaatcgaa gaaccagcca caaaaatact
     3361 tccttctaaa gcatagtaaa cctttccatt tatgccgtaa ccaattgtcg tcaataaatt
     3421 atttttggat aattgcggtt tttcaccggt attcatgaca ataaatgaac ctgtaccata
     3481 agtattcttg accatgcctg gttcgaatgc catttgtccg aataatgcgg cttgctggtc
     3541 tcctgccatc cctgaaattg gtgcttcgct tccataaaaa tgataacctt gcgtataacc
     3601 ataaacttct gagttagaag tgacttttgg taacatcact cgaggaatat ttagtaaatc
     3661 taaaatctcc tgatcccaat ctagctgatg gatattgaac aacatcgtcc gactggcatt
     3721 cgagtaatca gtaacatgtg cttgtccatc ggtcagtttc catactaacc aagaatcgat
     3781 cgttccaaac atcaattcgc ctttttcagc tcgttcttgc gcgccttcta catgatcaag
     3841 aatccagcgt atcttcgttg ctgagaaata ggcatcgatc actaaccctg ttttttcgtg
     3901 gaaaaattct tgatagcctt cattttttaa gttatctgca attccagctg actgtctgga
     3961 ttgccaaaca actgcatgat agattggacg tcctgtatct ttttcccata ttactgttgt
     4021 ttcacgctgg ttcgttatgc caatcccagc aatctgattt ggtttgatcc ctgattcgat
     4081 gaacgctccg gcaataactg actgtacaga attccagatt tcatttgcat catgttccac
     4141 ccaactttct tgcgggaaat attgcgtgaa ctctttttga gaactgccga tgtgtcttcc
     4201 tttcttgtca aagataattg ctcgtgagct agttgtacct tggtcaatcg ccatgatata
     4261 cgttgattct gtcattgtga ttccctccat tatatgcaaa cgctttcttt aactactctt
     4321 atcatactac tgttttaaaa aaagaaactg tcaaaatttt attctttttt tctttttttg
     4381 acagtttttt attatgaagc tattttttaa tcaattcttt tcttttttca gcgtctctat
     4441 tcttcttttc aatcgaataa tgtcgtaagg tgacgcaaat tctgacagat aatattcaca
     4501 ctgttttttg tttctctggc aaaatgtgat caccaaatca tattctttac cttcttcata
     4561 acttccaatc tcaataccgc cgattcccct cagttctctg atcagatatt gttgaaaagc
     4621 aatacgataa atcggcagac tttctaaatc gattccaatc actactggtt ttgcaatata
     4681 aaaatcgatc atcaaaagaa cattggcata ctggatcatc aggtaactaa gctcactatc
     4741 ttcagctctt ttcctcggca attgctgcac cgctgtttcc tgtaatttcg ccagtaactg
     4801 tgttaaggaa tgcccgagca ttttctgctg ctgttccaaa agccgatcac gctcatagac
     4861 ttcgatcttt ccaacaaaga aaaaccattc attgttgatc tgggaaattt ggtagcctac
     4921 tgccttttct tctttgattt tcaaacgacg aggacgataa tgccataaca tcgtttcccg
     4981 aatgtaagta tctaaaacag cggttggtaa ctttttgctc cgtgtcaaat catactgata
     5041 aaatatttct tcgtctacta tcgaaaaaga aacaaaaaag ctgtaaaaca tcattgtttc
     5101 gtatacattc agttctgctg ctgttcgact aagatgcatc acgatgattg gatcgattgc
     5161 ttgataaagc cggtccgact gatagagtaa tttcttttct ttcaaagttg cgtacgtact
     5221 tttttcattc aatagtcttt ttttcgtaat cccgagccag caagcaatct gtgcttctgc
     5281 tgatgccgta aacgttgttt ctaatacacg gtccaatcct agaatgaacg gtcttttttc
     5341 tggtgtattt tgcaaaaaaa gcggtcgctg atcttccggg atatattgga atagttcata
     5401 ataaaaatat cgtatctgta gctcttctcc gtataattga ccgtttttga tttgtaatcc
     5461 aaattcctct aagagctggt tcaattcttt gatctttcga aaaacagaag actcactgat
     5521 attaaacgct gtcgctaatc gaacgatgga tacttgctga tgttctaata aatagacgag
     5581 catcttaaac ttcaagcttt cctgcaataa aaacaataga attttttcca aacttacatc
     5641 ttcgtccaac acaagcagcg cctgatactc atttcgctgt acttctactt ttttttccat
     5701 cattcggcca atcaattcaa tatcttccaa atattgatca aacgaggctt ttgacagttg
     5761 gacatgctct ctcaaaccat tgatagaggc tgttccccct tgcagaacaa ggtttcgcaa
     5821 aatcaggatc tgtaactgct cttttctttc taataatgct tcaatcttca taggcagtat
     5881 tcgccacctt tgaccacacc atatctggca cacggtattc tggctggaaa aatagctcat
     5941 gttcttctaa ctgttcaaac gtccatcctt cttctactgc aattgtcagt tggtcaagaa
     6001 ggtggaacat ctcttttttg ctttggagct gtgctccaag aatctttttt tcagaatcaa
     6061 atagaaattt gagtttaact ttgctttgat ttattgctgt aagcttgtag tctacgtatc
     6121 ctgtttcaat tttttgggga taaaaaatgc tctcttcttc tgtcaaacct acgcttccta
     6181 agaaatagcc aaaccactga ttgccgactg gacgataggt tccctgatcc tttgtctgtg
     6241 agccactaat tgtcttgctg acatttcgtg ctgtacggac agcgttattt actagagaaa
     6301 catacatttt ttcatttgtt ggacgaaaag ttacttggat cgcatcgcca atcgcataaa
     6361 cgtctttttg agacgtttgc aagtagtcat ctacccagat cgttccatca tcattcaatg
     6421 ttaattgttc ttcccacatc tgattgtcgg gacgagaatg attagccagc aaaacaagat
     6481 catagttctc ctttcttttt tccgtctcta caatagcggt ttcattttcg gtcaaagaca
     6541 caacttgttc ttctaaaaaa agtgaaagcc cttgattttt catttccttt actaacggtt
     6601 ctgtcatttc aggatctaga taacgaaaaa gaattgactt tcggctttcg taaagatgga
     6661 tttgtttttt tcttgatgcc aacccttcag ctatttcgat tcctgcttgt cctgcaccaa
     6721 taattgcaat tttctttgca ttcatgatct tttgctgaag agccgttacg ttttgtatct
     6781 ttttaactgg gtgaataagc gttgattctg cagaaatatt tcgaaacttt tgatttgaac
     6841 cagtcgctag aatcaaacga tcaaaatcca atttttttcc tcctgctaaa acgacttttt
     6901 tttctttcaa tcctattact gtcttttctg tgtaaacatg gattcgatag cggtcagtca
     6961 gttcttcttt cgtgatccaa gaaagttgtt tttcactggt aacctttcct tttaatatca
     7021 aattgaaccc gctgggaatc catcctaact tcgattgctt ttcaatcaaa tatatttcac
     7081 ttgttggcat caattggcga agataaatag ccgcatgaat ccctgcaaac gacccgccga
     7141 caattacaat gttcatctgc attcctcttt cttataaggt gttctactgc taacttctca
     7201 atcagaaaac acagtattca taactcgctt tcaaccttat gatacatagc gatgcagcag
     7261 aatcaaccct ctccatcata ccgtgttcta ggtctgcttc tcaataatgt actagtggac
     7321 ctaattgaag agtatcattt ctgaagagat gtttcaaaaa atgtactctt ataaaagaaa
     7381 aaaactcgcc ttttacgtac ctctgtccaa ataggaaaca gaaaagaacg aaaagacgag
     7441 ttttagcgtg tgtaatgtaa tagttagaat agacacatca tttattttta attctttaat
     7501 gcttcaacaa ctgcttcgcc taattgatga gcagattgag gattttgccc tgtaagaagc
     7561 cgcccatcaa tttgaaccac ttctgaaaaa gctgctccag actgatagtt tgctcctttt
     7621 tctttcaaag catcttctgc taagaatggt acttcattcg ttgtaccatt tgcttcctct
     7681 tcttcattac tgaacccagt cactgtacgt ccagctaaaa tagattttcc agactcatct
     7741 gtaactggca acaatcctac aacaccgtga caaacagctg agaccagccc ttcatttcga
     7801 tagatttgtg aagcgacttt cccaagatct attgcttctg gaaaatccca cattgttccg
     7861 tggccaccag cataataaac cgctgcataa tcatttgcat ccacatcatc aggacgtaag
     7921 gtatttccca aggcccgatt tctgaaatct tcatcttcat aataggccca atcgatttca
     7981 tccatattca aaacactttg cggttctaaa ggtacatatc cgcctttagg actgacaaaa
     8041 tctgcatcga tcccattttt tactaataca tcataaaaat gagtcagttc acttaaccac
     8101 aaacctgtag gacgctcgat cttttcgtac ttttctacat ttgttaatac gatcaatact
     8161 ttcattttcc catcctcttt ctataaaaat tgcgttattg ataacgtgct ttcaagaaat
     8221 tatataatgg gcttggcaaa taaagctctt tatatgcttc ttcaaaaggt ttcgttacaa
     8281 attcatcctc acggttttcc aataatttct ctgcccagtc aggatcgacg atcatttgct
     8341 gtccaattgc tgcaagttct gcatatttca atacctgctc tacatcttcg cgattgcgga
     8401 tcccaccgac accaactaaa gggatctttc cttgaatcgt gttatggacc acttcaagaa
     8461 tcgatttatc gttgtattta tcagaacgag ctattcgatc atacatattt aatgaaacat
     8521 gcagataatc tagttttgac tcacgtaatc gttcaagaag ccagatcgtg tcttcaaaac
     8581 ggatacctgg tgtttcatat tcttctggtg agaaacgata ccctacgatg aatggttttt
     8641 tagcatattg ttcaaccgct gagaaaaccg ttgttaataa ttcttcaata aaacgataac
     8701 gattttccaa gctaccgccc cattgatcct ctcgtctatt cgaatgcgga gagaaaaatt
     8761 gttggatcaa atacgtattt gctccatgca actcgattcc atcaaatcct gattcaatcg
     8821 ctctacgtgt ggctttgcca aatgcttgga ttgtttcaac gatttcttct tcactcattg
     8881 ctcgtggtgt ttccgcatca ggacgttttg ctgcaactgc acttgcagat acaggctgtt
     8941 ctccagataa agttgctcga cttgtcattc gtccaccgtg gaaaatctga ataatcgctt
     9001 ttgcgccttc tccttggatt gctttcgcta gctcacttaa tcgaggaatc atttcatcat
     9061 gagcgatgct gagttcacct ggccagcctt ttccgatatc ttggacattt gcagcaccag
     9121 taataacagc accaagacct ttagaacgtt gtttataata agtgatctca tcttcggtga
     9181 tcactccatt gaaaaagctg agttgtgtcg tcataggcga cagcatcaat cggttcttca
     9241 attgaactcc tgaaggtaaa gtaattgatt gatcaaattg tgacattgtc attcctccca
     9301 taattcgctc tgattaacct atcgagaatc atctatcatt aaaccactcg attagttgta
     9361 catgcaacta atttgcttaa aaaattttat tttttttgta acttatctgt tgcatcattc
     9421 attgtctggg ctaattcttt acttgcttca tttcccaaaa ctgctttgta tgactgatga
     9481 agttcttccc agctaccatc gacttcctta gcaaattggc gtccttgttc tgtaagataa
     9541 actaatgaca agcgaccttc gctaactgtt ttgacgtatc ctttatattc taatttttca
     9601 acaaaacgag caatcgttga tggggcggaa tagagcattt gtgcaatatc tttttgtggt
     9661 attccatctt tttcttttaa tatcaataaa ataaaaccat aagttggtgc cagacctgtc
     9721 cttctaaacg cttcatcagc taatttattc aacatgcgat ctagcttttt cacgctaaag
     9781 aaaagacatt catctaacgc tttttcaatt ggcttttcca tttcatcccc tccattggcg
     9841 tacatatcat agtatgattt ttattttttg tcaaaaaaca cggaataatg tccgcctcct
     9901 ctgtctagat ttgaaaaaaa gaagtagcca tcttcaaaga atttcggctt gttttcgaca
     9961 aaactccttc tggaacaccg tgaatcagag gttgtgaaaa agtcgtttag ttttgagtat
    10021 gaagaaaaat tttgtgaaaa tggctttcca catttttgca taaatttggc ttaataccga
    10081 aaaactggct tttgaacacc gtttatatca gaggttgtga aaaagccgtc ctgcatcaag
    10141 taataagaac agccaaacaa aaatagttcc tcatattttg tcgttttttg agctaatgcc
    10201 gatggtcagc tgattgtaca ccgtttattg agaggtcgtg agcctgccgt tgaactccga
    10261 gtcacaagga gcaatttcaa aaaacagctt ctcatgtttt atgactatgg tgacttgtga
    10321 tcgaggagtt ggcaggagaa tactgtttat tcgtaaagaa ggggctgtga caagactttt
    10381 gtcacagtcc cttatttcct tttattatag gatttcgcca tttgattgga tgacttgtct
    10441 gtaccaatca aatgattttt tctttaaccg tttctttgtg ccattccctt cgtcatcttg
    10501 atcaacatag atatatccat aacgttttga catttgtgaa gtagaagcgc tgacgatatc
    10561 aatgcagccc cacgacgtat aaccaaataa atctactcca tctttgatag cttccttcat
    10621 ctgctcaata tgctgcttca aatagtcaat gcggtaatcg tcttgaacgg ttccatcttc
    10681 ttctactttg tctatagctc cgagtccgtt ttcagctatg aacagtggtt tttgatacct
    10741 atcatataat tgattcaaag caattctcaa acccttagga tcaatctgcc agccccattc
    10801 acttgatgga agatacggat ttttaattcc tccagttatt aagtttcctt ggaccccttc
    10861 ccaattttct ggatgagcac tgactgcact agacatgtag tagctaaaag aaacaaaatc
    10921 aacagggtag gctgctaaga tttcttcatc acctacttct atttttaagt tgacaccttt
    10981 ttcttcaaac attcgttgcg tatacgctgg ataatatcct cttgcttgaa catcactaaa
    11041 gaacaaagaa gttctttgct gctcaattgt tttttgaata tcatccggat cacaagaata
    11101 cggaacaaga agctgatagc tgatcataca accgacttgt gaacctttga taatttcatg
    11161 acaagctttt gtagctaaag cacttgctat aaactgatgg tgtgcacctt ggtatttcgc
    11221 ttgttccaaa tggggatggt tttcttcaat tactcctacg ctaacaaaag ggtgatgttt
    11281 tacacagttg atctcattga aagtcatcca atattttact ttatttttat agcgtttgaa
    11341 tactgtttca gcgaaacgaa cgtaaaactg aataagcttt cgattaggcc atccaccata
    11401 ttctgtaacc aaatataacg gcatttcata atgggaaaga gaaacgactg gctcaatccc
    11461 atattttaga cattcgtcaa acacttgatc ataaaaaaat aatcccgctt cattgggtgt
    11521 ttcttcatca ccatgaggaa aaattcttgt ccatgcgata gacatccgat agcatttaaa
    11581 acccatttca gcaaataaac ggatgtcttc tttaaagtga tgatagaaat catttccgtg
    11641 tcttttagga taataatact tgctgttggg atcctgcgcc gcttttactt gctgatgcgt
    11701 catcatatgc cattgatctg tccatttttc tttaggtaaa tcgctgtcga atgtatacac
    11761 atcagacaca gataatcctt tttcatctac atcccatgca ccttcacatt gattggccgc
    11821 tgtcgctccg ccccataaaa atccttctgg aaattttttc atatcgatcc ccctaaactt
    11881 gctagttttc ttgtttgatt atttttctta tgactagtaa tgatattttt gaatctacta
    11941 ctatttgtaa caataaccat tgtggtcgga tcatatccct ctttgattaa ttcttgcaaa
    12001 tctacttcca tcaataaatc gcctttacgt actttttttc catcagatac tgcactttga
    12061 aagtatttgc catttaaatt cactgtatca ataccgatat ggatcagtat ctctgctcct
    12121 tcttcactga ctaccccaat tgcatgtttc gttggaaaaa ctgttgaaac ttccccgttt
    12181 acagaactgt agatttttcc gtccgttgga atgatcgcaa acccttctcc taaagatcca
    12241 ctagcaaatg ttggatcgtt tacttcagat aaatcaatta tttcacctgc tgcaggagta
    12301 cttaacacta tatcctttga ggattcttct tcgatttcat ccttgtagcc gaaaagaaaa
    12361 gttagcatac aggaactgat catcgctaag aaataactag caactagcca aacaaatcct
    12421 tcaccaatat aaatcgggaa agacaaaata cttcttgtag caactgccaa agcaccggct
    12481 cctgcggcac cagctactcc accaaatata gctccacata tacaagcaat gtaaaatggt
    12541 cgtttatatt taagagtcac accataaaca gcaggttcag tgattccaaa taatgctgtg
    12601 ataaatgcag ataaagataa actttttact ttcttatttt tcgttttcaa aaatacccca
    12661 agtactgctc ctgcttgcgc agctacggca gtcatacatg ctggacctag cgtatcacga
    12721 ccgtagaaag aaagattgtt ggtcattact ggtacaagtc cccaatgtaa cccaaaaatc
    12781 actaacactt gccaaaatcc gccgataaca gcaccagata aaacagggct aaagttataa
    12841 acagctaaat atccagctgc aatcagctga cttgcataat ctgcaattgg acctacaact
    12901 aataaaataa ttgggaccat cacgatgata caaatgaatg gtgtcaataa atttcgaata
    12961 ctttcgtgca agcttttgcg aatcttaggc tcaatataag aaagaaccca tacagctaaa
    13021 attgctggaa taaccgtact tgtatacctt gctagaatca cgggcatccc tagaaatcgc
    13081 aaggttatgc tatcactata tgcactgaca atcgtaggat aaacgagagc tgctgcaata
    13141 accatagcga tgaaacgatc tgtattgaac ttttttgcag cagtatatgc caaaaatata
    13201 ggcaagaaat agaaaaatgc atcagctgct gcattcaaaa tgatataagt tcctgattca
    13261 gtagttaata aattcaaact cgtacataag gcgagtactc ctttgatcaa accacttcct
    13321 gccaagacgc ctaaagtcgg ggcaaaaaca gcggcgatca tgtctataaa agagtttaaa
    13381 atgccttttt tctcagttcc tctctttcca ctagatgcat catcttctag tttcatttgt
    13441 ttggataata cgtcatacac ttcatttact gcatttccta ctacgacttg aaacattcct
    13501 ccagcttcga ctacagtgat cacaccttct agttgctcta ccttctcctt atctgccttc
    13561 ttattatctt ttagggtaaa gcgtaacctt gttgcacaat ggtaaacatt gctgacattt
    13621 tcttcgcctc cgacaaatcg gacaatatct ttcgctaatt gtgaatagtc catttttact
    13681 tcccccttgt taattaatgc cgtagcaatc cttcttacaa gataagtata gttcttagaa
    13741 aacggtttct ccattcaatt agtacccctt ctaatagcga acgaaactgt acaatagtgt
    13801 gtatggttta cttagccgag caaatcactc actgcttgaa agaaaacaag tatatcgttt
    13861 ctcttatagt caaaggagac aaaaaaaaca cgcttgatct tcctttgctg atgtataagt
    13921 ggtatctcaa gctgatactc tgtgattttt gtttctactt ggcttttgat aagacagcac
    13981 aacaaagtct cggcatttaa cggaagcata actaggtcag aactaggaga gattagttgc
    14041 tgaatggaat ctatcttttt atggattttt atttgatttt cttctttgta gtaatgatca
    14101 agcagttttg ttttcttttt ttcttcaact atggtcagct tttcacgcaa aatctgataa
    14161 atctcccaag attcaaactc atctagaaca ctaggtagat aaatcaaatc atcccactca
    14221 aaaataagct cttgctcagt agtcaaaatt gcatcatatt ccgttatttt gtttgattga
    14281 tttttgaaaa gatacactgg ttctatccgg cattctttga tccacatgtt catactttgt
    14341 tgaatctgtt tttttagtgt attcaaaata ctaattggct ggttactaac aatcagtatc
    14401 tccccttgtt ttcgaaaagg attcaacgct tcggcaagat acaaaacaaa ataagcgctt
    14461 tcagctaaat tgggacgtaa ttgaaaatgt attgggaaga aacgccgaat taaataaatt
    14521 tctaaaggat aacgggagat gatcttttgt acaaaatgat tcatggtatt atgtccggca
    14581 tccatcctcg ttttcatttg tttgatatgg gttagcaaaa attctgtttc atggaacaat
    14641 aacgaaacag gaagatctaa aaaacgaata atcgtttgct caaatgctct tagattcttc
    14701 tctatttctt tgtttttttc atcattaatc atcaaataat ttaactctaa tagtcgattt
    14761 tcaattgctt gtttttcttg attggaaaaa gaatagggta gttctgatga taactttttt
    14821 gtgagggtct ctaccatcgg aataaataat gtatacctgt ttgttttttc taaaagttct
    14881 tctcttcgaa gaatggtcaa aacgagatac cgagaaaatc gtatgaagtc ctctcctgaa
    14941 acaatataat tatatgatat aagaacctct tttaatgtct tttggacagt cggcatgata
    15001 ttggaaaaaa ttgtactgat ttgttgagga aaccttgcgt gttggatcac cgtttctgtt
    15061 ccaacaagag ataagaaaat tctttttgaa ttttcttcag caatgatttt tagtcctttt
    15121 gtcgacgaaa cttccagttc taatttagga ttgcgctcga tccaacgcaa aatcgttttt
    15181 atttgtaatg atacggctgt ttttgaaaga aagaaaatgt ctgctatctt ttgcatactg
    15241 acataccctt tttgaaacaa taagtacgtc acaatagttg aagctcggaa atccatgctg
    15301 gaatagattt tatgtttcgt cacctcttgt atgatttgct gtttagtttc agattcaatt
    15361 gattctaaaa aataacctga acgtttattt gactggataa tgattttctt ctcgtagata
    15421 gcaagcatat ttttgatttc agtttggatc gttttcttgt tggtacctaa agcttcagct
    15481 aattcttcgc ttgttatcca atgattctta tttcttaata ctacaagaat ttggagttgt
    15541 cgtttattta agtccatttg cttacacctc ctctttgtta taaacataca ggaaaaacct
    15601 ctcaaatgac aatagtcact tgcagaggtt taaaaatcat ttgaagaaag atctatattc
    15661 aaggttttta ccattagact ggataatttg tttataatat tcaaaactat cttttttcaa
    15721 tctcctaaag cttccgctcc catcattttg tctatccaca taaataaagc catatcgctt
    15781 cctcatttcc cctgttcctg ccgatacgat atcgattggt ccccaccata agtaaccaat
    15841 gatttggcaa ccatctttta ttgcctcagc aatttcctga agatgtattt ttagatactc
    15901 acaacgtttt ggatcgtgga ttcgattcaa ttcatctggt gcttcatcta gtccaatgcc
    15961 attttcaact atgaataatg gtaattcata acggtctgtc aattcattca tgacataacg
    16021 aaaccctaga ggatcaattg gccaactcca aggttcggga gatttttcct tcaaaaaggg
    16081 attatcgaaa ccatttgctc cgccagtatc tacgcgcatt tctgcttctt ttttatagac
    16141 agcgctacga taataactaa atgcaatata atctgccgtg ttagcttgca agcactgttc
    16201 gtctccatct aacattactg gtgcacagtc ttcttccttc catgtcctgt aaatataagc
    16261 tggataatgc cctcggcaca tgacatcgga gaaaaaccat gaattgcgtt taaattgcag
    16321 tgaaccaaat acattctctg gatcacagtc atatgcataa gtcgctaatg cagaaaagct
    16381 acacataata cccatcttag catttggatc gattttcttt aataattgag tagcacgggc
    16441 gttcgctaga aacatatgat gacaggcttg ataaatcact ttttttgtta gtgtagcaat
    16501 gggttcaagt ttatctctag cagggaatgt aaccaatcca gcagctgcat aaggcatacg
    16561 aaaagcatta ttgatctcat taaaggtcat ccaatatttc actttccctt ggtagcgttc
    16621 aaagacggtc tgcgcataaa attcaaaaaa gtcgattaat tttcgatttt gccacccccc
    16681 atactctcct accaatgcta agggggtttc ataatgacta agagtaatta ctggctcgat
    16741 atcatatcga tttaatgtat tgattagtct gtcataaaat acgagaccag cctcatttgg
    16801 cttctgttcg tctcctcttg gaaatattcg tgcccatgag atgcttgttc gaaaagcttt
    16861 taaacctaac tccttcagta aacgaatatc ctcttcaaat cgatgataaa aatcaatcgc
    16921 ttcatgagaa agataatgga gtgattcgtc taaagcaatc tcccaaatct ttttttcttc
    16981 attccactga atactaggat gctggttcat gatcccgata agcgtatctg tcacattagg
    17041 taatttgccg tcttccaacc atgcaccttc acattgatta gcagctactg ctccgcccca
    17101 taaaaaattt tctggaaata tttcctgatc cataactatc tctcctcgct atcaacaatt
    17161 tcttacttga agtatagctc gattcatcaa aacaagatat tctaactatt tcggcagaag
    17221 agaagaaaaa aattgaatgc tactcttcat ttttaatatt tatatataac aaatacataa
    17281 gacgatcccc gaaagaaaac actcgttaac catctaagca aacgatttat tttacttcca
    17341 acacaaatgc ttcataaggt cgtaaatcaa ctttgccgtc tggtaactgt ttcagaggat
    17401 aatttgacac aataaccctt aaagcttcac gtggaatagt gaacgtctgc ttttcactgg
    17461 acatattaca aataacgagc cattgctggt cttcatatat gcgagaatag gcaaagacat
    17521 gctcaggcgt cttttccact aattcatagt ctccccagac gatgatgtca tgttttctac
    17581 gcaaatcgat caatttcttg tacatataaa aaacagaatc ttgatctgct aacgcttctt
    17641 ctgcattgat ttctttataa tttggattga ctcgaagcca tggaattcca gtagtaaacc
    17701 cagcatgttc acgggcgttc cattgcatag gcgtcctagc attgtctctt cctttcgcct
    17761 tgattgattc caagatttcc tcttttgtaa atccagaaga aatcctttcg ttatacatat
    17821 tgattgtctc aatatctttt gcttccgcga tatcatcgat tgggcaattc gtcatgccta
    17881 actcttctcc ttgatagata taaggggtgc ctttcatcat atggagcaag atagcaaaca
    17941 tcttggcact ttcttttcga tacacatcgt catttcccca acgagaaaca attcgcggaa
    18001 gatcgtgatt attccaaaat aaactattcc atccttcatc acctaaagat gtttgccatt
    18061 tggataatac ttttttcagt tcagagatac tcaagggttt caaatcccat ttgtctttgc
    18121 cttcttgctg atctaatcct atgtgttcga attggaagac catggataat tcatttcttt
    18181 taggattgga ataaagttta gcgatttcgg tagttgctcc ccatgtttcg ccaacagtca
    18241 tcagattttt gtcaccaaaa gttgcttgat tcatttcctg aagatactca tgcagtttag
    18301 gtccattact tgtgatttct ttatccggtt ctttgccaat catatcgatc acgtccatac
    18361 gaaagccccc aataccttta tcgatccaga aattcatcat ttgataaatc tcttggcgaa
    18421 cctgtttatt tttccaattc aaatcaggtt gacgcttgct atacaagtgc agaaaatatt
    18481 gccccgtttt ttcatccaac tgccaagcag aaccactgaa tattgagcgc aatctattag
    18541 gctcttttcc attgaccgga tcacgccaaa tataatagtc ccgataagga ttttctttat
    18601 ttttacgggc ctcaatgaac cacggatgtt catcagaagt atgattcacc accagatcca
    18661 tgatgatacg gatatttctt ttctttgctt cttcaatcag ttcttccatt tcttccatcg
    18721 taccgaattc tgccatgatt gcttgataat tactgatatc atacccattg tcatcattcg
    18781 gagactcgta tactggagaa agccaaattg catcaatacc taaatacgcc agataatcca
    18841 acctggaaat aatcccccgc aaatctccaa taccatcttg atttgaatct tgaaaacttc
    18901 ttggatagat ttgataaaca actgaatggt gccaccattt ttgttccatg attttcctcc
    18961 tataaatgga tgtttctatt ttttgcttaa tcatttattt tagtctctct cactaaaaat
    19021 tgtaacgctt tcaaatagct attgcacctt gttatcggta acagaataaa acaaaaaaac
    19081 agctgaggaa attccctcaa ctgttttttg aaaggattga tttatgcagg gaagaatgct
    19141 gatttcacaa cttctttata aacggtgttc actcagctgt cccttggtat tagctcaaaa
    19201 aacggcaaaa tataagaaac tattttttcg tttttttctc taatactcag gccagaacgc
    19261 tgatttcaca acctctttat ttcacattca atatccacat gaatcccaca aatacaaaga
    19321 acagaccata catgattgga gatacttctt ttcctctttt agctgctaac atggtaattg
    19381 gatagaagat aaaacctaat gcaatcccat ctgaaatact ataagtcaaa ggcatgccga
    19441 tcaagatcaa gaatgaaggg atcgcaatct ctaagtttcc ccattcgatt tgtcgcaaag
    19501 attgtgccat caatactcct accataatca atgctggtgc agttacttgt gaagtaacaa
    19561 ctgatagtaa tggagaaaag aacaagccta acaagaagaa aatccctgta gtaatagctg
    19621 tgatacctga acgtcctcca acggcgatac cagctgatga ttctacaaat gcaccaacag
    19681 gagaagtacc aaataaggaa cccgcaagca tagctgttga atcagaagct aaagctttcc
    19741 ctacacgagg catcttgttg tctttcatga aacctgcttg gtttgctaat ccaactaaag
    19801 ttcctgctgt atcaaagaaa gtcacaagca agaatgtcag cactacgacc cacatttgaa
    19861 gagaattgat gtcccctaca tgttttaatg caactaaaaa tgttggtttc aaacttggtg
    19921 ctgcggcaac aatttcagaa ggcattggaa tcaaacctgt gaccagacct aaaatcgttg
    19981 tagctgccat cccgatgaag atgccacctg gtacacgccg aacaagcaag atagcagtta
    20041 cgactaatcc aaaaatcgtc aaccaagtag aaccaacgtt gagtgatcct aatcctacta
    20101 atgtagattc attcgaaacg atgatcccac cttcgctcag accaaggaaa gcgataaata
    20161 gaccgatacc gccagaaatc gcatatttca aatctgctgg gatcgcatca atgatcattt
    20221 cccgcagctt gaagattgtg atcaaaataa aaatcaaaga agcaacgaat acgccggcta
    20281 atgctgtttc ccatggaatc cccattccta aacaaacaga ataagcaaaa aaagcattga
    20341 tcccaagagc aggtgccgtt ccaattggat aacgggctaa tacccccatt aaaatacagc
    20401 cgatcgcact ggctaatgca gtcgcagtaa acactgctcc ttcatccatt ccagaagcac
    20461 ctaatacagt tggatttaca aataagatat aagccattga gataaatgtt gtaaatcctg
    20521 ccagtacctc acgttttacc gtggtgttca atttttctat ttcgaagtag gaaagtattt
    20581 tttccttcat cttccatccc cctaaatccg aacattataa ataaagtccg ttaaaatttc
    20641 gatttattaa taaaacaacg tgttttatca tatactaaaa caaaatataa gtaaacaaaa
    20701 aattcggatt ttaagcaaaa tccgaacgtt tcatctgatt aaatcccttt atctcaaagt
    20761 tcatgaacat tcactttgga ttacaagaat ttctttattg tgttaataaa gtttcttcat
    20821 tctagtctca aaaatcaata gtgtgatttg attttaccat ttcgtttctg ttattctttg
    20881 atgaattctt ttgtatcgac aggattcaga ttatttagtc cgccaaaacc tgtgtcgacc
    20941 atttttcccc agccttttgt cttctttttt cctgatttga gattctttgc tcgaagcttc
    21001 tcactatgtt ttgctcgccg atacttcaaa taaccttcta atcttcccat tagatccact
    21061 gtttttcctc ctttttattc aatcagacga ctcagctttt cctataacaa aataattgcc
    21121 ttcagggtcc gaaaaattga aagtcaagac gccattgttg tctgtgattt ctcctggttc
    21181 ttccatgttc tcgtagatag tctcaaattc gtccgtaaaa aacactaaag aaggcggtgg
    21241 tcctaatact tctggtgaaa atttctgcac aaatactttt gggaatacgc ctaattctaa
    21301 ttcttttgag atgctgagta caatactctt aaattcttct ggcaattcga ttgtttcaga
    21361 aatttctgca ccaatttttt ctacaaagaa tcggcaaatc atctctacgt cattgacata
    21421 aagcatcaca cgtgtttttt gtatcatcgt ttgacccttc tttctatttg attttctttc
    21481 ctgtctataa actgattcca ttatatcacg aaagcgcaaa caccttgtgt ttgatactat
    21541 tcaagaaaaa taaagcaata gtttctagga ttgctttcct ccacaaactt tttttacaaa
    21601 aaaaaaaaaa cggcaatgaa tgccgctctt cttttttcga ttcttttata attctgcttc
    21661 tgattcatct ttggttagtg tgtgtctaac actagttacg ccaaatgttt gatcgatttt
    21721 ttccttcaac gcttcgattg cctgtgcgcc acgtgccgct tgttcagcat tgatggattc
    21781 aatgaccagc accgctgctt gtgtttcttc cgtcagcatc gttctttggg cttcacgcca
    21841 gttgagacag cgacagatcg ctccttgttc atcatagtag atgatttctt ccggaagtgc
    21901 cggagcatcg gaatctgcac ctaaaggcag gaatgattcg ccaccttggg cttttcctaa
    21961 atgcagattt cctgcgatct tttcgatatc ttctccgccg caaggtacgc caaaagacaa
    22021 ggaaatacta ttatagatat ctacaagcgg attgattggg aaaaattccc gttcttgatt
    22081 tgcacgtttc agtaaagctt caatagaaga acgtgcacct tttttagtct tgaatgtggt
    22141 aaatgcctga cgccactgag caatgacttc gttttggctg aatgtttctt ctgtaaggta
    22201 atttcttgct tcttttgctg cctcattcaa taattgatga tacgtttctt cactttcttt
    22261 tgttacgtgg ttatcgatac catttacgga taagatttcg atggttgctt caggaaatac
    22321 ttcccagaaa ttggtatcca ctattacttt tttcatatgt tcacacctct tgattagaat
    22381 aattgcttga tgaatagata gtctgtttgg ggatcatctc ccatataaaa aacatgttcg
    22441 ctgtatttga taaatccttt tttacgataa aaagcgagcg caacatcgtt gtgttcccaa
    22501 acaccgagcc aaatggctgt tttttgcttt tcttttgctt tttcaatagc tgtatctagt
    22561 aaaaatgtac cgataccttg atgtttaaat ttttttcgta catagattcg ctcgatttct
    22621 aaaaaatgat cagccatttc ctcagattga ctcgttcctg tatttagttt caggtaaccc
    22681 gcaggctctt gatcgatact cactaggaaa aaatcggttt ctttatcttt tagctcttct
    22741 gtaagttttt ctggcgcata agcttgtgtc aagtaatcag ctaaatgctt cggtgaatta
    22801 tcttttccaa atgtatctgt aaatgtttcg atactgattt gttgtagtaa gtctacatct
    22861 gaaggcgtca tttttcgaat ttcgtattta ttcacggctt cttcctttca atagatcctt
    22921 ttattgcctt ttttgacaaa attccaatct tcgctaacat tcttgcatac tttatttaaa
    22981 agatattcca attgttttgc ttcttcgtca gaaagaccat ttaatgcgac tgcattggag
    23041 tagttgtttt ctcgaatgat gaaaggatag atttctgctc cttttttagt cggatagagt
    23101 ttcttgattt ttttattttc tttatcttcc aaacgttcga tcatcccatt ggattctaat
    23161 ttcttgattg ctcgggcagt cgttgtacga tctactttga tcatttctgc tagtttttct
    23221 tggatgattc caggattttc gcaaatacgt actaaataaa gatactgtcc tcttgttaaa
    23281 tcgacttctt tgaattcgat attgctgata gaatctagcg ctcgggcaat cattccgatg
    23341 tctcgaagga tttcagccat ttcatcccac ctttattttg tttgtaagac tagtttacct
    23401 ctttttgttg caaatgcaac tattttcaat aaaaaaatca agttcttttt taataactag
    23461 taaagtatat tcttttcttc ttttacgaaa aagctcaatc acaatagatc tggtttttgt
    23521 tttctaaaat aagtaactgt ttcttcgttg ttcgcttttc tgatagcttt ggcaactctt
    23581 ctatactaaa aaatcccatg ttggaagttt cattattctc aataaacttg gcctcttcac
    23641 cgtggatcgc acaagcaaaa acaagtttat aatactgaaa aagctgtgga atatcttttt
    23701 gtttattcgt atcaaaaact gctcgcaact gagtagtttc tactgttaat cctgtttctt
    23761 catagacttc tttacgcaca ttttcttcag gagacaatcc tatttcagca aatccaccag
    23821 gaagtgacca ttctttcgtc cgtttatctt cgattagtag gaccttgcca tcttttttga
    23881 tataggcacg aacatctact tttggtgttg gatgtccttc tccaatcgtt gtgagcgctt
    23941 ttatttcttc gaaagtttct tttcctattt cactgatcag ttccaatgaa atcgtccgga
    24001 tctcctcaaa acgctcttta tcaaatacat cttttccata atatagacca gcttgagaaa
    24061 gtgcgagtag tcttttgtat tgagccaact tcttgttcat tctcttccct tcttttttag
    24121 caaatgtatg actatgtaat caagtataga agactagttt aattacggca aataaatata
    24181 atgaaatctg caataaataa aagaatgtta aaaaactcga gaacaaaaga cattcgactt
    24241 ctctggggct gtgaataaat ggcgttcaaa agcttgcatc tgcggtaata agccccacca
    24301 aacgaaaaat atgacgagct attcttgtct ggctgttctt attaattgag gcaggacagc
    24361 tttttcacaa cctccccact aaacggtgtt caatcagctg atgctcggta ttcactaaaa
    24421 aaacggcaaa atatgaggag ctattttgcc gtttttttct ataatactca tattaaaaca
    24481 ctgacttcac aacctcttcc ttaaacggtg ttctcctacc aactcctcag tcacaagtca
    24541 caatattcat caaacatgag aagctgtttc ttgaaattgc tccttgtgac tcggtgctga
    24601 acggtaggct cacgacctct cggtaaacgg cgttcaaaag ccaatttttc gatattaagc
    24661 catttctttg ttacttattg tcattgattt tttttctaat ttatccaata gtggagtgta
    24721 atccacttga gtatagtctg ttacatcaaa ttcatatagt gttcctaact ggaatttgtc
    24781 atattttcgg tcggcgatga tctttttgaa tgcttctttc gtaatatgat tggtcccttt
    24841 cgttcgatct tccaatacgt caccatagtg ataatgatcc atgatatagc tcaaatgacg
    24901 atctgattca cgatcacgtt tgtaccgacg ttgccataac acttcaaagt ctgctgttag
    24961 gcgaatcgtg atcacctgat atccgtatct atctgctaat tcttggagtc gtgctttttg
    25021 cttatcacta aaaggatact cggacacaat cactttcttt cctgcttcca tatacaaatc
    25081 aagtgctttg taatagaaag gataaacttt cgtcctttct tgttccgccc gttcttccaa
    25141 attgttaaac ccgatggatt ctgcatagta ttccttgatt tcatcgagcg tgatggcata
    25201 catatctgga aatcgttccc gtagtttatt cataagatat gtttttcctg taccaggact
    25261 accagccaga agaatgaaat actttttcat ctcatttatt tcctaagtta attggacttt
    25321 ccaagttcat aaacagtcca atcttatgct tgacaatttc ttttactgct tcatttgctg
    25381 gaatcacatt atggcgaaga gacttgttga tttctgtttc actaaaggtt tctttagcta
    25441 ctttcgtcca gttgactaaa agctccgttc caacattgaa tttgcggatc ccgttattga
    25501 tcaattcagg ataatcttct tctttcacac ctgttcctcc atggataact agggggacat
    25561 caactactgc atcgatttct ttcagcaagg gaatgtttac ttctgttttt gatttgaatt
    25621 gtccatgatt cgtaccgata gcaatagcta atgcatccac gcctgtagct tctacaaatt
    25681 tcactgcgtc ttccggtctt gtatatacct tgtcattttc agcgacatgg attccttctt
    25741 ctgtaccgcc gattgttcca agttctcctt ctacggaaac accgtgcgca tgggcatatt
    25801 ctactactgc ttttgtcttc aggatatttt ctttgaaagg cagatgggac ccatcataca
    25861 tgacagaagt atatccgctg tcgattgctt ctttgatatc atcaaagtct cgggcgtggt
    25921 ctaagtgcaa gactgcatca accatttctt cttctgcaat agctgtcatt acattgacta
    25981 acacatgcat gctgatatat ttagcagtat cgacacttgt ttgaataatg attggcgaac
    26041 ccatttcttt tgctgcgcct agcatggcag gaagcatttc taggttatgc gtattaaaag
    26101 ctccaactgt aaaattcaac tcttctgctg tttttgttac ttctttcaat gttgtataca
    26161 tcttttattg ccaccttatc tttttatttg tttcctttga tcgttacttg ttttgcaatt
    26221 tgtcgcatct catccatttt gcccatgtag taatcgatcc cttgatcatc accagcacga
    26281 gcagcatctg aacgcttctg gttatagagg ctcatcagtt ttttataccc atctccgatc
    26341 gtctgtttat tttccaagct cttttctaaa tattggatgg cttgatcgtt ctcatacaat
    26401 tcagaaaatt taagtccaac ttgttcataa agttccgcta atttatgcct atcttgggta
    26461 gtggaaatct cttgtttcaa ttgtgtaatc tctgattgaa tcttttcggt cgcttctggc
    26521 gatagggctt tttcttcttt tgccagaact tttttcggtt ctttttcttt tttcttaaaa
    26581 aatccaaaca tcattttccc tactttcaat taaaatgctt tcaaaactgg gcttaagatc
    26641 caggcatata agagtgctgc ggctactgta tctacatcgg ttgctgtagc attgatgaat
    26701 cccatcgaat taaagatcgt tactagcaaa gcgggcaata atgtaataaa gaaaccatga
    26761 gcaataccgc caatgatcgc tcctcggcgt ccgccaactg cgttgccaaa tatccctgct
    26821 gtccctccgg caaagaaatt ggttagcata ccagataaaa tcatcgctaa gccgaacatg
    26881 ggcaaagtaa acatggcaat aatcgtacca atcgttgtcg taatgaaacc taaaatgaca
    26941 gcatttgggc tataaggaaa gaaaactgga caatctaagg cagggatcgc atcaggaact
    27001 aatttcatag ctatccctcg aaatgccggc acgatttcac ctaacagtag acgtacacca
    27061 gctagcaata catacacacc cactacgaat tggatggctt gtaaaaaggc aaacatgata
    27121 tagttttgat ctcctgataa ttcagaagcg aatggttcgc ctgcaaataa aacagtgatg
    27181 atatatagcg ggaccatcac gaccatgaca gacaaataag tatcttgcag aaattcgaaa
    27241 tgtgtcggca acttgatatc ttcgatcgac tttttatttt cgcctttctc accaaaaagc
    27301 ttagcgacac cggcttcaaa taagtacccg atcgtacaaa aatgacctaa agcaatatca
    27361 tttgatccag tgattttacg aatgatcggt tgcgctactg ccggcatagc aatggcgaaa
    27421 caagctccga taaaaccacc gaccaagatc aatacgatcc ctcgcagacc ggcaaaatag
    27481 ccaaagactg tcgtcatcgt tgccatccat aaaattgctt gaccattgat agattcaata
    27541 gaagggatga tcccttgcat atgaaatcct tcagtaaaga ttttcccgaa ataagttaaa
    27601 cttccaacga tgatgctcga accggcactc aacacttgaa atcctaggag tgtctttaac
    27661 gtgccagaga tgacttgtcc tgctgatttc ttctgcagta gtagacccaa catagcaatc
    27721 aatgcaatgg tgatcgatgc ctgagtcaaa atattttcga tgataaaatt gataacgctc
    27781 atgtttttac cctcttttct ttttgtattt agataactcc cttatcttgc agaactgggg
    27841 tgattttttc ttcaatttca ttttttgaaa caatattttt caaatagatc atcgccgttt
    27901 taggatcaac tgcgaacttt tcgaactgcg aacgaaaatt ttctgctgtg atgatcacat
    27961 ctggtttcat ggaaactgcg gaagaaatat cacaatggtc cagtttggct tctactccta
    28021 atttgttcaa aacatcctca gcagacatct gtgctgcaaa actacttcct aaacctgcgc
    28081 cgcatacgaa taaaatgttc aatttgttca tctttgttct cccccgtatc atttattatt
    28141 tctcaactac tgaaaaaagc agttgtttga aatcttcgat atttgtgcat tcaatcaatc
    28201 gatccaactt ctcttcgttg ttgatcaatt caattagttc tttcatgatg ttcagatgcg
    28261 agtaggagtc tactgctgcc aaacaaaaaa taatctttac tggatccatt tcaggattac
    28321 cgaaatcgat tggttgctca atcgtagcta cgctgactcc taatttattg accccatctt
    28381 ctggtcgggc atgggctagt gccatgtgtt tgccaatcac gatatacggt ccgtaatcat
    28441 tcactgcacg aatcatcgct tcgacatagc gctcttcgac aatgttttct ttaaccaatg
    28501 gtctagcagc tagttcaatc gattcctccc aagtagtggc tttttctttg atcatgatat
    28561 tgctgtccgt caaaatatct tttaacatag gctggatctc ccttttgttg atttctaaat
    28621 tgtttgtttc gaataatttt tctaacttgc catagatgat tcgatctact cggccaccac
    28681 tttctttcat gacatctatt atttgagtga ataactccgt cgattcatga ctgttaggct
    28741 ctaaccgctg tagttcttca tttcttttca aaaagtcttc tataaccaag atattcgtct
    28801 cagttaaaat cggatcgaca actaaaagcg gcttatttcg ataattcaat tgaaaggtgc
    28861 tgaaaaccag attgacatcc aatttatcta ctaattcgat ttcttttgaa cttaaaactg
    28921 cagtaatctc gatctgagga aacttttctt tcagattctc tgctaacaga tttccagtag
    28981 ccatcccatg gttacagaca acgactgatt tataaacata attcaagtct cgcttgatta
    29041 cactggcgat cgtcaaaaag tggatgacaa gaaaagctat ctcgtcctcc agtatcttgc
    29101 caccaattac ttcttcgatc gtaggaacaa aatgagtgac tgcgcggtag attgggaaat
    29161 aatttgttcg gatgttttct ttcaatggat tcatgacttg gatatgattc ttacaatcag
    29221 tgcagccatg tgcttataga gattttcgaa taaagcttct tcctttagat ggaaaggtac
    29281 gtgtgtctcg ttctctacaa attggatcaa ttggatcgtt agtaattgag cttgtaccca
    29341 ctcgattgaa ttggagatat ctctagcatt gaacgtctca atagtgaaac gaagataatt
    29401 tctttctact tgcgggacat tgtccaattg aaattcctcg atcatgtggt caataaatgc
    29461 agaaaagcta ctgtctttta tttctgtatt tttccaatta atggcagaga taaattcatg
    29521 tttcctgatt cgctggatcc agatcaatgt aaaaagcagg atttgttttt tataaatatc
    29581 atcttcttgt ttcaacaact tattggaata gatctcctgt atttttttga tttccaccaa
    29641 aggaaaataa tggagaaaga ttttttgagc cggtgttaat tgtgcatctt gattcataaa
    29701 gaagtcggtc attcccagat tctgattgat aaaatcatag atcatcgtac ggatagatcg
    29761 ttctgaacct ttataaacca gtccttgctt tccataactg acgatctcta tcccataact
    29821 gaccagtgtt gctcgtaacc gtctcatatc ttcatctaat gtacttttag agatttgaaa
    29881 ttcttcttct tttttgttta gatggatcgg gattcggctg taagcaacgg ctaaaactag
    29941 atcaaaaata cgttcgcgcc gattcaaaaa gccgtctttc acatctttta tttcagtttc
    30001 taatcgagct tgcttttcct tttccagctt caacaaaaaa cctttgttgc gaattgtacg
    30061 gatctccgga agctttttac tgctcaacca gatattcgct tcaagaactt cctgacggat
    30121 cgtccgctga ctgacattga actcacttgc tagatgtttt gcttttactg gatattgggc
    30181 tgtcatgatt ctgtgaagta tttcaattgt tcttgttttc atagaaatga tctccttctg
    30241 atttcaagta tatggttccg cttacataat aaaaagtaga tatttctgcc acttgaagtg
    30301 gaaagaaagt aagcaaagca aacaaaaaat aagccatatg ctttttcatc tcctcaacga
    30361 aaaagacata cgcctattat tacaaaaatt ttgcccatcc atacaaaaaa gaggttgtga
    30421 aaaagctgtc ctgcatcaag taataagaac aactaaacta aaatagtgct tcctattttt
    30481 tgtttggttg ttcttattat cgcagatgca agcttttgaa caccatttag tggagaagtt
    30541 gtgacagaga tgttcagcct tgagcgataa gaagcgattt tgaaaaatag cttcccatat
    30601 tttacaaaat cgtgccttat tgccgatagg ctatctctgg cacaccgttt attcagaaaa
    30661 aggagttgcg acaaggcttt tgtcacaact ccgttcataa atatttcctg tcaatccagc
    30721 ataatcggct gaataaaatc ggcttgccat cttttttctt tctcagaaaa atcaaaatac
    30781 catatctgag aaaaatactg tcgttgtgtc ttacttcctg agatcaatcg cccatctttt
    30841 cgatcgactg aataatcaca gcatctgaaa tcaattcgga tggcaaaact attttcgtgg
    30901 atctgtcgat aatttcctac ttcctgaata gttatttttt taggtatgat ttcttacacc
    30961 gtctgctttg tttttttgca gaactttctg attttcggca aacagcttgt ctgtataaca
    31021 gcttctggct ttttcaggag tttcttcttc ccaagcggat tggatcttca tgaatatctt
    31081 ttggatttcc agaaactgtg ctttcttttc tttagccgtt cctgacatgc gggacaatat
    31141 ctccgctttc agccttttct tttgtctttt attcttgacg atagaaaaag cagaaacccc
    31201 tcctactgac aaaacagcta atgcaagaaa tcccgtttgc tcataactag aaggacctgt
    31261 acttggacca taatacccat aagaatctct gccgtaagaa cgactgccaa aataactgcc
    31321 cccatatgaa cgaccgccaa atgaacctct gcccgaactt cgaccgctag atgtacctcc
    31381 accatgacca cccgcgacag cgaatccttg ggtcggcaga gcaaacaaac ataggcccac
    31441 taacaaaatg attgctaaat aattgatttt tttcattgtc ttcctcgtta tcttttatta
    31501 caaaaaacta tttttatcat agccttgcta aaaggaagag tcaataacca gatgcataaa
    31561 ctgttttttt agcaattttg tcttatttag tcattgagta acatcgaaca gatgtatgtg
    31621 tcggcagtcc ataattcctc tatcttcagc atgaacaagc ttgcagacaa gagatctgcg
    31681 cttcctccag gagagatttg gttttcctga caaaagtgca acagtgctgt aaatgaacga
    31741 tttggtaaag cactttgact agcagcatga gcaagttttt gcatttccac taacgttttc
    31801 taatcactgc gatgcaatac gcatgtgtca tctagcgaac tcatcaaaac taacaacata
    31861 tgcatttgtt tctgtacata tgaatcatta tctagctcct tagctgcttg gattgcaagc
    31921 ctgatatgcg gataccctaa tattgcttct tcatatgcac catttacgcc atatttttgc
    31981 ttcaccctat gaccatgagt gtttttttta tgacgatatt ttgtatcagg aaaagcagca
    32041 agcttgctga catcatcaag tattttcgat aaagaaaaag gctgttccat actgattttt
    32101 tgtgcaatga cactgatcaa tagccccatt gcccaaatcg ctcctttatg ggtattgatg
    32161 ccatttgtag caatcagcat tgccttttcc gcttttcgcc caatctcagc aattctttct
    32221 cttaactcct gatcaatagc atgatgccat gctatttgag ccatttcttc aaaaaaagga
    32281 gttagcgtct tagcagactt aagaaataaa gcatagtcca tatcggaatg tgcacccgca
    32341 tccagtgcat ccactaatcc aggttttgga cttaatgtta cttctgcgat caatgcttcc
    32401 tctaccaacg cagcgagttg ctgagtcact gctttttttc gttcgtcatt tatcatgaca
    32461 ctcactcctt cttcctacta ttacttgctg aaaccttttt tgatagctac ccaaatgata
    32521 tgaagtaacc agcttaaagc aaatgcacaa cttgccgtca ttagataagc tacaagaatc
    32581 atgactcctg aaggtaactg cagccaacta tctttaaaca ataataacag tacttggaaa
    32641 acaaatacat tggctaaata cgtacgataa gcataaacag acaaccattt gaacaatggc
    32701 aattttggcg aatcgtttac aatcattttg gaagcgccta tgaagacagc aaagatgatg
    32761 actaaactgt ataaactttg gatcgtattc aagtaaggcg cattcgcaaa gctcaagtct
    32821 cctggatgtg cgagcaatga acggacagaa aagaacgcga taactaaggc aacaggtaag
    32881 aaaagataac gtactctgtc caaatattga taaacttttt catgataaac aaatgcggct
    32941 accccataaa tcccgtaaat catgaaacta gcaacaaacc gatctaacaa gtaccagctg
    33001 tcatgataag gcccagtcaa tacttgtgtt tgatagaaca gataccatgc gacatataaa
    33061 atcgttgaac caatcaatac tggccataca tattttttat tagcaaatac tttgtaaccg
    33121 agccaaacaa aaaacggcat gaacaattgg atctgcagca tcataacggt ataccataaa
    33181 tgaggcgctc catcacctgt gacatatttc agtaaaaagc ttgcagtatc gtatacggag
    33241 tttgttgttg gactgctgga aatagccaaa gataagccgt cgtccataga agatacggaa
    33301 cgactagttc aaaaaacttt tctttcaaaa attcccaata agacaaatgc tggcttgttt
    33361 ttaccatatt ataaacaatt gcaaaaataa acattggtgc tgtgtattta acgatgacgt
    33421 aaaaggtacc aataaaagct gtatttgttg cgctgtggct gtttgccaaa gcaaagctca
    33481 atatcgtttg catcataaca gcctttacag ctgatacttt ctggaagtca cttacgttga
    33541 ttttgatttt tttgttttca aacatctctt tctctctctt tttctttatt accaaagttc
    33601 tttagttaat ttaggtcctt cgactgtttt caatagaatt tttttctctg gctctctcaa
    33661 atactctttt agtgaaaaac cgccttgccg agtcactact tgggtatcga attgctcaaa
    33721 aaaagcagga tgcgattgaa ttacctgaat tggcaattca atcggtgaat ttgcgtacag
    33781 tagcaaatca aaatcactgg tttcttttac tgccggaatc ccagtcgata attcaaatcc
    33841 taagctgccg ccgattcccc atttacatcc tgataatatg tttctagcag catgaaattg
    33901 ctgataaaca ggataatcca tgattttctc ttgtctatac gattcttgtt cgatgatgtc
    33961 ccacggatga atgacttgtt tgacggcatg ttttgagatt tctgttgccc atctctgatt
    34021 gcgggcaggt ccacgtaaac caatcggtag tatttctgcg tgatccgtcg acgcacgacg
    34081 aactgttccg aacatctttt cagttagaac gacccattca ggcaaggtga acccttctat
    34141 ttcatgttta tcaaaaagga caatatcatg tgcttgaatc attttttatg catcccattc
    34201 ttcgtccatt ttggcacgga ctttatttgt ttcgacacgt ccgaatgttt tggctgtttc
    34261 gtttgtgtat cgatttgtca gcatcgtgtc atttgtattg cggacatctt gaatggcttc
    34321 attgattgct tcgatgactt tgctgacatt ttgttctgaa gcagcttggt cggtgatatc
    34381 ttctaggaaa tgatagatcg ctcctagttt tgtataatta ttgatatcgt aagcgatagc
    34441 tggaactttt tcagcagctg cttcgatttc agcaaccgaa cgttttgtca cacgtgcagc
    34501 actttcttta gacatcgctt ggacggtaat ttctttattg tttaaagcaa tcaagcggct
    34561 tgattgtaat ccatgtgcta aaaatgcacc tgaaatagca tttcctgcaa tcaatccaat
    34621 aactggatat ccagcttgac ggaattttgc ataagcagca gcactattag ccaaagccac
    34681 atggataccg attaattctt cgttatagcc gtatgcttgg cttggtacat cgatcacaac
    34741 gatgattggc cgtttcactt ttttatcttt atcttcttcg taaacgtgat ccaaaatttg
    34801 tcccatgcgg aaaccttcaa ctaaaccaac ttcaccgttt cgtacacggt acatcgggtt
    34861 tttaggatca ggtacgattg atatcacgat ggtttcttct atgaatttac ttgatttacc
    34921 ataatacaca gtactaatag aagaagttgg atttttcatg ccagttagtg ccgcaaacca
    34981 atcgtaacca acacttgctg cagctggttc atttccttct gctacttctg gtaagtcaat
    35041 tgattttgct tgatggttag caattgcttc attgtaatcg tcaatggcca ttggttttga
    35101 aagatctaaa gaatcaagta atgataaata aaatgctgag ctttcactgc gatgcgtgtc
    35161 ttttcgttcg tccattgctg cgatgacagc agctttgatt gcttctacac tatcagtcac
    35221 taattcatca atgatttttg actctacccg ttgacgagat cctaatgtat tccaaataaa
    35281 gtctttgtca ctagaatcaa attctcgaac gcctgcttct tgttcaataa cttctggtcc
    35341 attcaaaccg actctcgctt tttttgttgc gattaaataa ctcattaatg ctgaagtaat
    35401 cgacataccg ccaaatgatc ctacacgtcc tggaatcaaa ccgatgactg gtacatattg
    35461 ttttagagca atgattacat ttccgatttc tgaaatagat aacagtccgt agtttgcttc
    35521 ttgcaaacga acaccacctg tatctagtac aatgactgga aagatctcat ttcctttttt
    35581 attttcttct aacacatgtt caagtgcagc aacgattttt gcaccggaaa cttcaccgat
    35641 accgccacct tggaattttc cttccatagc gattactact gcttgtttgc cattgatcgt
    35701 gccacggctg acaacgatcc cgtcatcact ttcagggacg attccttgtg ctggcaaact
    35761 tggcgcgatg atttgatcga atggatcaat caattcacgt ccattgtcaa gtagagcgtt
    35821 cactcgttct ctggcgttta attctacaaa actatttttc atctgaaagt tcctccattg
    35881 cttgcgtcaa tcgtaggtac acaactcctg gtgtagcacc gaagtcattg atcacgatat
    35941 ctgctgaaat tggataacga tcaaaaaatc tcgttaatac attgttccat acttcgccga
    36001 agccatcgct tcctgtacaa atttttacag tagattctgt tttttctgtt ggaaacatca
    36061 agatttccaa atctcctgaa ccgaccactc ctacatggat tttcttattg atcggctgtt
    36121 tcgttggata tttataagct aattgttcca tggatctctc ccctttttgt aaaacagagc
    36181 atacacgttc tgcttattcg tctttcttct tccatctggg taaatggcga caaaaggttt
    36241 ttctcgccaa ttttatgacc aagttctgaa tttcattggt ggttcataca ggccatctga
    36301 ccattcgatc aaatcatcga ttgtttgtgc agctaataat gaacgtttcg cttcactgcg
    36361 tttgatacct agatcttctg gtaatttcac gatgccggct tcacgcaagc tatctagtga
    36421 ttctttcgtg ctagtcattc caagaggtgt aacaccgcca attgctgcaa ttgctgcttg
    36481 acgttcttct tttgtttttg ctttgtacaa ataagcaatt ccttcttctg tcacgatatg
    36541 ggtagtatct tcgctataga tcatcactgg tgcattggct aagcctgcct gtttttgaac
    36601 aactaatgca tctaattctt cgacaaagac tggtttttta tttgaaccat atgtttcaac
    36661 catttgaaca actaattttt gtcctttacc taatggatca tcattgtcgc gaagtgattg
    36721 ccatgctggt gtagaatgac gacgaccgcc aggattatgt cccatgttag gcgctccacc
    36781 aaaaccagat aaacgtcctt ttgttacggt agaagaattt ccttcgtaat ctaattgcaa
    36841 ggttgaaccg ataaacatat cgattgcata ttgtccagct gcttgtgata atgttcggtt
    36901 actgcgcatc gtgccgtctt taccgacgaa aaagacatct gggcgagcag caatatattt
    36961 ttccataccg acttcaccac cgaaactatg gatactttca acccaacctg attcgattgc
    37021 tggaatcatc gttggatgtg ggttcaatac ccagttcttc gcgattttcc cttttaaccc
    37081 tagtgattca ccataagttg gcagtaataa ttcgatagct gctgtattga atccaatacc
    37141 gtgattcaaa gattgtacgc cgtgctctgc gtagattcct ttgattgcca tcattgccat
    37201 taggatttgc aattctgtga tgttttgagg atctcgtgtg aataaagctt ctaattgata
    37261 aggttcatct gcttttacga caacgtctac ccagtcacca gggatatcta cacgtggtaa
    37321 agaatcgaca acttcattga cttgaacgat cacgatgcca tctttgaaag ctgcagcttc
    37381 gacgattgtt ggtgtttctt ccgtattgaa acctgtatac aagttgccgt ctttatctgc
    37441 tttatctgca actactaaga caacgtttgg tatcaaatcg atgaataagc gtccataaag
    37501 ttccaaataa gtatggatat cacctaattt cattgtgccg tcttcaatca tttgggcgac
    37561 acgcaagctt tgtgcacctg cataagagaa atcgatcttg cttgcgattc ctttttcaaa
    37621 aatattcaaa tgttctggtc gtgagatact agacatgatc aaatgcagat cattcacttt
    37681 ttctgcatct actttttcaa gactttctga aagaaaactt gcttgttttt gattgtcgcc
    37741 ttctaataca actttgtcgc cgggagcaat cagtttttcc attacttcta cgattttttc
    37801 agtttctaca tacttgccat tgagcaagtt gctgattttt tccaatcgct gcgctttttt
    37861 ttcgcgttta gaagcccagt tgcggtttgg tttttccata attagtcatc tccatttttg
    37921 atatagaaac gtggcgtcat caataccatg ttggtctaga ttgatcgtac ggatcccttt
    37981 atctacacca aattttgtat gaatcagctt tgtcaaagta ttgccggggg gaaattcaat
    38041 cgtcagatcc attcctaatt cttttgccaa gtccatcatt tggttccact gcacagggaa
    38101 agctagattt tccaacaaat ctttacgaat ctcttctgcg tcctgagtgg ctcttccatc
    38161 cgtatttttt atatacaaac atctggcatc agatagatgg acagactgca tatacggctt
    38221 gaatttcttg accgtatcat tcatcaagag acagtgagat ggcacaggga ctttcagcag
    38281 cttcgctgtt tgcgcttggt gccgtttggc ttctgccaac gtaacggata aaccttcgat
    38341 actcccagat aacgtatgtt gcatcggaca attttcattt gacagataaa ctggatggtc
    38401 aggatcaaat gttttggcta ccatttcctc tgcttcgctt ctcgtcacac ctactactac
    38461 gcccattgca taaccgcttg gatatgcttc tttcatcaag actgcgcggt gatagactag
    38521 ttccgctgca ttctcaaatg tcaaagatcg acaagcaaca gctgcacaaa aagcaccgat
    38581 cgaatgtcct gctgcaatat caggctgaat accatttttt tccatttcat ctaaataaaa
    38641 tactgctttt gtcagtaatg ctagctggat aaaaaccgta tcttgatagt tttcttcttt
    38701 atcgactaac cgataccccg tcacattttc taaacgttcc atgtacattt cagggatatc
    38761 cgctaacatc cctaacttct gactgccttg tccaggaaat aagaaacctg tactcatgag
    38821 cctcgcctcc tcagcactta ctttttccac tgctatctta gtcaatttct gctataataa
    38881 aaaatgccaa aaaaagaaaa aaccataaca aaaaggtatg gatgggatgg ataattatga
    38941 aattgcttca tctgcagtat tttaaaaaag tattcgaaac aaaaaatgtt acccaagcag
    39001 ccaaagaatt atttatttct caacctgcct tgagccgtgc gatcaaacat ttggaaaacg
    39061 aattaggtgt ccctttgttt taccatagcg gcagaaacat tgagacgacc gtttatgcag
    39121 aagaatttta tccatatgca gtcaagacat tatacacatt agaagaagga atcaattatt
    39181 gtcttcggtc aatgagaaga tcgttacttc cgtcatattg tatttagagg tagcttctgt
    39241 ttctattccg aacttagtcc gaatttttat ggaaaagcat cctgatatcc aattaacgat
    39301 catgcaacat catttaccag atgatattac cgatcctgta ctgtacatca cttcggagat
    39361 gaagcctggc atgaccaata ttcctatcat gaaagaacct gtttatgtcg ccattcctaa
    39421 gaaacatcct cttgcgaaaa aagaacatct gcaattagaa gatatccagc gcacccccat
    39481 cttgatgctg tcaaagagca acgccttccg tcatacactg gatgcagcac ttgaagcgaa
    39541 aagtatcgaa ttgacgatca gttcgacgac agatgatcct gcgacattac gttctattgt
    39601 caagcaagga ttagctgtta gctttttccc aaaagtttct tggtcttacg ataaaaatga
    39661 tcctttcgtc ttgcgggaaa tcaaagattt gcccttgaca cgaacaattt atttatcttc
    39721 tagcttcaca gaagatcatc ctttgatcaa aatgattgca aaaacgatgc gggaatttta
    39781 tttaggaaaa taaaaaaaaa agagctggga caaaattctt gtcgcagctc ttttttcgaa
    39841 caaacggtgt tccagaagta atttcttaga aaataagccg aaatttccca aaaatttgag
    39901 aagcaatttt cgtaaattcc ttcttatttc ttgaagctaa acatttctgt cacaacctct
    39961 tctctattgt cctagacatt cattgcgttg atttaaaact tccatcaatc aaatctgcta
    40021 gttcatctag cttttctatt ttacgtagat caatagagat ccaatgttct ttattcatgt
    40081 gataggctgg aaaatacccc tcttttcctc gcaaaattcc gccaagttca ggatcgacct
    40141 tcaaatcaag aatattgatg atcctatggt cacttgcatc atcatagatt ttttcttctg
    40201 gaacagacat caggacccca aaccattttt tgcttttttg atgtctgaat acgcaataat
    40261 caggaaattt tttaaaaata tattctggag acaaattgta tgtttcattg atgtgatcga
    40321 ttagttcttt tttcgttagc atctgcttcc atctctttct tattgattcg ctttattcaa
    40381 agataccacg taagaataga aaaatgaata caagtagctg ctaatcaaat acttcgatat
    40441 ttttcttttt tatcaactct taaatgttca atccgcctgt gttggtcttg ctatcatcta
    40501 ctattaaaat gttgattatt gtttgcccac ctattttttg attttagtgg tatcattttt
    40561 caagttcatg atgaaattct tatcatcagt aaatgctcca gaaaaataaa caatgattga
    40621 aaaatcagtt gaaacttgac caccgtttat tttctccgta ttcttagaat agaagggagt
    40681 ctgattgatg tattcactaa tgaaaaaaat cattaccgaa aaagatattc gacgtcatgt
    40741 ttctttagta gaacaattgc tgaatcatac aaagataacc gtaaatgaat tagctgaaat
    40801 catagggaca accgaacgaa cgatttattc tgaccttcaa tctattcgct ctcaactgcc
    40861 tgaaggctgg gacatcatta gcgatcaagc agggattagt ttgcaaaacc agcaaaattt
    40921 attagcaaat gacctttggg agattttttt caaacaatca gtcagtgtcg aactattgaa
    40981 aagtctgctt tttacaaaaa aagttgctgt ccctgatttt ctagccgacc atgggctttc
    41041 ttatgggaca ttgaaaagac atgtgactaa aatcaatcag cgtttagcaa gttacgactt
    41101 gcagatcgat ttgacgaaat ataccgcttc tattcttggg aaagagcgtg cgattcgcac
    41161 tttctatcat cgactgctga ttccttttac tcataacaac tattttttcg aagattattc
    41221 gattcatgaa tcccattatt ttcaattttt aaaaacaata aatcgaacgg agctagcggt
    41281 tgaaacagaa gagatttttg gaacatgttg gttctttatc aatacgatcc gtataaaagc
    41341 gaattgccga ttagattctt ctatccatat caacagtaca ctctcctccc tgtatgactc
    41401 tgcattgaaa aaattgtatt taacggaagg tatttatctc aaagacactg agctttcttt
    41461 tgcttctttc tgctttctgg aaagttggaa ttacaacaat aactatggac aagaaaccgc
    41521 ttgctgcctg catcattctc catttttcga acgcctcgaa acgtttgtag aggaactagc
    41581 ttcagagctg tctcttgatc aactaaaaaa acatctctaa ctgataactt ggctcttctc
    41641 gtattaaaat atcatgaatc gccgatattg attgaagcat tggaccgtca ataccatttt
    41701 ttttagaaac atatgatcag caatatgcac atttgtctca acagaaagag aatttactga
    41761 acgatctaaa aaaagaaatg gaaatcaatg aaccgaattt cttccttcaa ctcttatctt
    41821 tactgatcca acaaacgatt ttttctatca aaccgaattt gttcaatgtc tattttattt
    41881 tccaaggaga accttcatgg aaggcattct ttcagcagga attaaaagat tacctgggaa
    41941 aacgtgtctg cttcttacct atcgaactaa ccgatctttc cactatttct ttcgaaaaaa
    42001 cagatatctt gatttccaat ttcccgctgg attctctaga tatccctatc gtatacattt
    42061 cttctattcc tacgaaaaat gagctcaatc gtttgactga actcactttc aaaacttttt
    42121 tatagtaacg gctagcgact gtattctcta gctgtttttt cttttttgcg aaacagttta
    42181 ttcatgatcc ctttttctat ttctacaact aagaatagaa gaatcacatt tgctccaatc
    42241 aataactgtt gtgtcatcgt taaacttact gtaccgatca gctgctggcc gactggtaga
    42301 aaaataacca tcccttgcaa taaagcaagg atacctaatg aaagaaaaag cgctttgttt
    42361 tgcaaaagac cctggttcaa tgacggcttg gacaactctc tgcaattgat catgtaaaca
    42421 gcttgagcta agacgatatt ttgtagaaga atggtttgct gtaagctttg cccttcaaac
    42481 tgcatagcca ataaataggc aggaaccatg atcagtaggg agacatagat gatccgaaac
    42541 aaatgataac cagataggat tccttgcttt ggatctcttg gtgggcgctt catgatttct
    42601 ggatctggcg actcgaaccc tagtgcataa gataaagtga ttgtcgttac catattgacc
    42661 cataaaatct gtactgggaa caaaggtagc gggcgattca gcataagcgc ccaaatcaag
    42721 atcaatcctt gagctaatgc agttggcaag aagaaattga tggttttttg caaattatcc
    42781 aaaatccgcc ggccctcttt tacggctttt gcaatcgtat ggaaattatc atctcctaaa
    42841 accatatcag ctgcctgttt gcttacttca ctacctttga ttctcatagc aattcctaca
    42901 tcggatcttt tcaaagcagg tgcatcattt acgccgtctc cggtcattcc aacgatttat
    42961 ccatttttct gcaaagcttt aacaattcgc agtttatgtt ctggcgtcgt tcgagcaaag
    43021 acatcgacta ttggcacttg ctgaatcaac tcttcatcag acataagatc caaatcgatc
    43081 tcttctaaaa ctttggcagt atgttttaag ccaatttgtt ccgcaatcgc ttttgctgtg
    43141 tctttgtgat cccctgtaat cattttcact gagatccctg cttgttgaca ttcctttaca
    43201 gctttgactg cactttcttt tggcggatcg atcaatccgg cgatccctgc aaaagttaat
    43261 tgggttaaag tctcatgcgt gagttcctgt ttcgaatcta cttttttata agcaaatcct
    43321 aaaacacgct gaccttttct cgcaaattct gcagctgtct gactccatgc ttcttgttct
    43381 gcagaagaaa gagttgattt agcaaataat acttctgatg cacctttgac gtaaatcacc
    43441 gctccttttt cctccgcatg catcgttgcc atatatttgt attcagaact gaacggaatc
    43501 tttgcttcta tttttttcaa aggcagattg gctgtttctg tgtgtcgaat cagcgcaact
    43561 tctgtcggat taccacttaa attttctgtt ttctgttctt cttttgtttt taattcctga
    43621 cagtttttca taatggacaa cacgcaggct tcttcttttg cagctacatc cacaactgtc
    43681 atttcatttt ttgtcaatgt tcctgtctta tctgaacaga tcactgtcat agaacctaat
    43741 gtttctaccg aaggaagtcc tttgatgatc gccttttctt ttgccatttc atgtactcca
    43801 acggatagga tcatggtcaa aacagctggc aatccttcgg gtaccattga caccaccaaa
    43861 gcaatcatag ccgaaagaag gatatgccaa tccataccat atcgaaatgt cgtaaaaata
    43921 actaagaata ggctcaaaca aagaatgcct tgaaaaattt gtttgtttaa tcggttgatt
    43981 ttcttaatca gaggcgtcgt ttgttgttcg acctattgca atgcttgatt gattttaccg
    44041 atttctgtcg tgtttcctgt ttctacaacg acaccgactg cagaaccaga ttgtacaagc
    44101 gttcctgaaa aagccatatt tttctggtcg ccgatcgatt cttcttctgt caaaacggca
    44161 tgactttttt cagatgcttc tgattctccc gtcaaaatcg attcttccac taataaatca
    44221 tgtgcttcga ttaatcggat atctgctgga acgacatctc cggcacgtaa gacaatgaca
    44281 tctcctttta ccagttcttt cgcagggatt ttttcttgca tcccgtttga tagtactatc
    44341 gcttcttgtc ccatcagctg cttcaaacca ttcaatgatt cttccgcttt tctttcttgc
    44401 cagtaactaa cgagtccatt gacgatcact acgaataaaa taatacttcc ttcaatatat
    44461 tcactagaag caaatttcaa aaaagaggca atgatcaaca cgatcattag cagatcagta
    44521 aagtgctttg ctattttttt ccatcgtttt gtctgctgcc ttgcttttat ttcattatat
    44581 ccttgatcag tcaggcgttt ctgtcgttct tcttgcgaca agccttctgt tgatgtttga
    44641 tagtttttca atacatcttc taccgtcaat ctgtaccagt tcatcctatc ccctcctgtt
    44701 taattgatac tgttattata cgcagggaag ttttttcagg cgtatcgatt atttcagggg
    44761 ggtctgaaat aattcgtttt gcagaatgta tctgggccta actgatattt ctattgctta
    44821 ttcttttata tacaaaattt aagaatacaa accagataac caataaaaaa ggaataaagc
    44881 gtgtcgtgct ttcgaataac aagctgaaag caattgaagt aaaaaacacc aacaaagcaa
    44941 gatctttata tctttgtgta gtgttccgtt tcttttcttt aataaattga acatgtgtac
    45001 acaagatcga agaccacaca aatagaaaac aactcgttgt catgcctgcc aaaagctgaa
    45061 aaaacaatcg actatcagct acaaaaaaat gtagacaaag accggcaaaa aataacattc
    45121 ctgtaattaa aataccgtgt aaaggtacgc ctttcttaga aagcgcacaa aaccaatggg
    45181 gcaaactttt ctcttttgct gtttgatata aaatcctgct agtactgtag actgcactat
    45241 ttgctgagga caaagaagca accaaaatca ttagattgac aattgctgct ccgccttggc
    45301 aatggatcat ttgcagcata gtcactaaag gactttcttt taaatctaaa caatgccatg
    45361 gaacaacaaa taaaatcgac aaaatcgttc ctatatagaa aaagagaata cgccaaggca
    45421 gacagttgat tgcttttttc aaattctttt gcggatcact tgtctcgcca acggttaacc
    45481 cgatcatttc aattccagca aaactgaata aaaccatagg aaatgagact accattccag
    45541 caaagccaaa cggtagtaat tcatcgatct gtccaaaatt ttctttgatt ccgatagact
    45601 gggtatgaaa atctgagaca ctcaatccta tacccaataa gataaaaagg aaaatcccta
    45661 ggatcttgat gattgagaaa aaagattcca attcaccaaa ccacttgact gcaacaaggt
    45721 tgactgccat taagatcatt agtgcgctac ctccgcttat caaagctggt acatgtacaa
    45781 accagaaatg gatatacaat cctattgctg ctaattccgc aagtccagct ccaagccagc
    45841 aaagccaata agtccaattg acaaaaaatg cccacttttt gcctaaataa tagtcaacga
    45901 aatcactgat agagttaaat gtactatttg ctaaaaataa atcacccatg gcccgcatca
    45961 aactataaat agccaaaccg catatcaaat aaacgagaat aacagctggc cctgctgatg
    46021 caattgcctt tgctgaacct aaaaataatc ctgttccaat tgcgccacct aatgcgatta
    46081 actggatatt tcgattagtt agagtccgtt tcattgccgg tttttccatc aagttcacct
    46141 ttttcttttt caagcagcat ggcgacttcc tgttcccaag aaggtttctt tattttttca
    46201 atacagagtg gtactacaaa caaaatgaca ctgatggctg tgactgcaat tagattgatc
    46261 catgttccag ctttcatcgt cagtccgaca gaaaatccga ttgccgcaaa taaaacaata
    46321 acgacagtcc aaactccaag attgctcttt ttctcttttt ttccaattct aaatggtcga
    46381 ttcaactttg catgtgtata acgcaatctc aaaactgcga tccccatgat gacatagacg
    46441 atacagtaga taacagtagt tgaatttacg agcatcaaaa atgcttgatt gacgccagga
    46501 atcagcaaat aaaaaagtgc aaagattgag ataatgacag actgagtcaa aataacggat
    46561 ttggatacgt caaattgatt cgtcttccaa aaattgaatt ttggtggata cgcacctttt
    46621 ctagcacttt ctgtcactgt ctttgctggt cctgaggccc aagcagataa ttggactgct
    46681 acaccaatga agacaagtaa actaaacaga ttcacaataa gatgtggcaa accaagaatt
    46741 tggcaataaa tcgaaataga ttgcgcgata ttattcaatt ccatttgtcc ttttggtacg
    46801 acatttgcta caactaaagc attcaaaata ttgacgaaaa atataaaaat taacgcggca
    46861 aatactccgc gaatatacgt tttaactgga tttttcaatc gagtgatata cacagaggac
    46921 atttcgatac cagtaaaaat aaacatgatc ggcgcaaaat aaacaaatga ggatgcagtc
    46981 gtagtatctg gtattaattt gtcccatgaa aaactgccta atgttccggt tggtacgatc
    47041 ccaactttga tccacgcagc aaaccctaat aagagcatca tcgtcaaagg cacgtacaat
    47101 cctaaccaaa caccgacttt tccgccgatt tttgccatat caaatttcaa attcaaaaaa
    47161 gtgatgatcc aataaacgac taaaataaca actaatgtaa atttgctgtt caaaccaagc
    47221 ggcacattat cgataatatt accaaacaac ggagcaagtg ctgaagcgac catcaccatc
    47281 ccaggaaaca tttggaccca taacagccat gagacaacga acccccattt ttttcctaga
    47341 gcattcgata cccaaagttc tggaccacct tttttgggaa acattccggc aaattcacca
    47401 gagatcaatg agattggaaa agcgtacaat aatactgcaa ccagcatgta aaaaatcatc
    47461 gtccagctcg ttgctgctac atctggaata tttcgtacac ttgctacaag ggcgcaggtc
    47521 attccgataa aggtcatggt cgtgatttgc tttgatgaac cagtatcttt catctttatt
    47581 ccttctttca atagcgacat atgtttttgt tttcttttat ttttgttcaa gaacagaaat
    47641 gacaaggttt catcgattca gtacaaaacc cagtatcacc gaaacatcca ttgaacgatc
    47701 ttagtgaact gggtttgata catgaaacga acgatccaac ttatagaacg ttttataaaa
    47761 aagaatatct tggcgaggaa tatatgaaaa acagggggaa atacaattgt tttgatgaag
    47821 caaataattg tctgttctcc atatgtctct tgctattctt tcacacaaaa atcagttcta
    47881 ttggatgatt tcgtttagtt tcttttccat tgctttggcg atttcttttg tataaaaatt
    47941 gaaaattcga tcatcattca aataaggagt catgatagcc gcacgtagca gagtgatttt
    48001 ctgttctttt ttccattctt ctttcgttag acccattctt tcaacaaaac gaatcggaga
    48061 atcaccgtaa tcttcttgtg taaatgtagt atgagaagta ataaaccgtt caccataaac
    48121 atcgccatcc atataagaag accgatcgaa cattttttca tttaattcat tgatagcgtt
    48181 caaatctgta cagccttgtt ctttgaatac ccaattgacc atattaaaat caggatgatt
    48241 caatggatag acttcgattg tttttccttt aacagtaaaa gtcatatgat cgagaaattc
    48301 tctgaatctt tgagctgcct cgattgaagc cccaatcaat tgaccgtatc cggtcacatt
    48361 caatggcaat acacgatgtg ttgtccagac tgcggcggcg gttgctccag cttttgatcc
    48421 ttccaaaata taagctccta acatatctgg agcctttact gatttttcaa acacatatgg
    48481 cgcgaaataa gaaatgatat ttctcatatt tttatgtttg attacgattc ctccagcagc
    48541 ataagggaca tagcccatct tatgaggatc tatcgtgaca gaatccgctt ctgaaatagc
    48601 tctgaaccct tcatatacct ctttgtcaat cgttacgcag tggtggaaaa catgatgttc
    48661 ttcaaagaat tcagctaagg aagcatacgg cacaaattct cctgcttcgt ttagaaacag
    48721 tgaacgcgca tagccgccat atgcggcatc aacatgtaaa tagaaataga taccttcatc
    48781 ttttaacctt tctcttaatt ggacgatttt atctacactg tctacttgac cttcttctgt
    48841 cgttcctacg acagcaacca cacctagaat tgggattttt tgttcagcta attcacgaat
    48901 tgttttttcc aaagcattaa tatccattcg ataatcctct tgaactggga tagcaaccat
    48961 ctgatctaag ccgactccgc aaatatctaa cgccttcatc caagaatagt gttttgtttg
    49021 agggaccagc catttcccta atctttggat attttttccg ctacgggaag aagctgcttt
    49081 gacctcatcc atttcttcgt ccgtaaagct ttcggtcatt tccaaaattt cttcaacaga
    49141 taaattcaaa agttcccact cagacatttt tttcactttt tcaggcagca cttccttgac
    49201 agctaaagga atcgatttga tgcagcgggc gtaccataat ccttcaagat tagcaataga
    49261 accatctgct gcaatgtgtc cccatccgtc tgtcatattg aataatgaag caaaatcctg
    49321 tcctacttct gcttccattt gcgaagttgc catagaagat tccaatgcaa cattatttgg
    49381 gttccacagc atcgcatagt tgtaagctaa taaagcaggc atcaatgttt cagcattcat
    49441 ttgtccccag taacggcctg ctgaatgcca tgggatcgat cctgcgcgta atcgctgact
    49501 gacttcatcc aagacctcta tcatatggtc gcgggtggct agataatctg gagtgagctt
    49561 atctccttcg ctaattgcag gcatatctga aggaatataa ttttctctcc atccaagatg
    49621 ttcatctacc atcttgttca acaacatttt ataaactggt ccattttcag ctttgtcgcc
    49681 tataaagacg gccttgatat ccatatcttt catttttctt ccctccatat tttgttggtc
    49741 aatgtctcgc agatacatgt gtttatctgt aacacctctt cactatagcg ccaaaaatga
    49801 gaaatttttt ttataacatc aaatccacgt agatttttac aaacaaaaat aaataaagtc
    49861 ggatttttct gataattaaa cgcaaaaaaa cgaacatttt ttcaataaat cagtgttcta
    49921 aaatagataa cctaaaaaaa gcgaacaaac aaataaaatg actgtccttc attcactaaa
    49981 catattttta tttttttata ttgttaaaaa ttcacaattt attttttaat agaattatct
    50041 gttttccaaa ttttataaca taaaaaacct tttttaacgg catttatatg ctttttcaga
    50101 aattaactga tgatttcaaa aagaaaacat gtcataatat ttcccatatt gtgcaaaaaa
    50161 atacaaggcg gaggctctac tatgattgaa gaatatattg agaaaaatat tttaagacag
    50221 ctgtttttat gtgggcaatt ctatgtaaat aaagaagtca atctagaaaa gctctccaat
    50281 ctcctgcatg tttgcaaaac cactttgctc aatgatatca ataacataaa aaaagaattt
    50341 gaagaacaga tcgcttatac acatcgggaa aaggaccgtt acactttata tttttcagaa
    50401 catatacctc gatgcaagat catgcagcaa gtgtctcaaa attcgttgtt tttaaaaact
    50461 tgtctgcttt atttggaaga agatgaacct gattatcttc aattaactga atgtgaattc
    50521 atctctgtca gcaaagctta ttcattaaaa aaacaagtat tagcttattt taatgactgc
    50581 gggatcgaaa tcgaccgcta ctcccctcga ctcactgaaa tggaaagacg tctgctgctt
    50641 cttaatgtgt cgtatcgttt aggcggtttt aattcttggg agctacctga atcgtttttt
    50701 gaacgtaccg atcgtttcat tgaatccgta acggaaaata gtggcagatt ttatgataaa
    50761 gaaaataaag aaatcttatc gattggtttt gctatcagtt tcctacgcca gcaagtgtgt
    50821 gctgtgacaa tagattcaaa atttatcgaa gaaatcaaaa aacgtcctat ttacaattat
    50881 gtcgaatcag catgggaaaa cactgatttc caaacctatt ataaaaaaga agaattcgcc
    50941 tttattttga cactattcaa tctttgtaat tatggtttcc attcttatca gttgattgcg
    51001 gaagactttc aacagctaca ccaagtgttt attgacaata ctcccgaaat aaaagaacta
    51061 gttgctacct ttgaatctca cttcaatcaa gaattattcg gaaaccaacc gttcgaacgt
    51121 gcgctgattc atctgatgcg ttcggcttgg gataactatc aattattcat gccagaaaaa
    51181 ttttatcttt taaatgagga acagacaaat ttatataaag aagtccagac aattttttcc
    51241 agctggtcca gccagttacc ttatgatcta cggttgaatc ctaattgcat gcgggctttt
    51301 gtgatcgaat tgagcggaat tctccgtctg acaaaagaac atctgactat ctatatcgtc
    51361 acaaattcgg atgttcatta tctgatttat cgggaagcct tggaagctgt aactactttc
    51421 gattttcaag ttgcaccaac aatttattca agtatatctg atataaagaa gtatgcgcag
    51481 cagtcctcaa accgggtatt atgtgaacgt acattatata caccagatgc ggtccaatat
    51541 gaaaatatta ttcctatttc gatcaatacg atcgatcgag ctatcatttc agctgtgcaa
    51601 aacaaataag gggctgtgac aaaaatcatg tcacagcctc ttatttgttg aagatgccca
    51661 tttctgtaac aatctcttga tacacgtcag gctcacaacc tcacttattt tggacatcta
    51721 cgggtccgat ctctttattt aaaaaataag aaatgatggt tcggataact accaacgccg
    51781 ctagttggaa aatatcctgc aaggtaggtt tgataatcga ttcgatgatc ccagctgaaa
    51841 caagaatttc caaacttaga agtatatagc ctcccaacat ctttttaata gcattgttct
    51901 cgctgactcg gtcgttttgc acttttgtat ggacaaataa atatttcaaa aaatccttga
    51961 ttgatagaca aacaccccaa accaataaac agatagcaaa gatatcaagt cccagtacaa
    52021 gtttttcaaa atatggaaga agaaactgca tcaactctgt cgtcatccta cctctcctct
    52081 tctttgtttt tctttgtctt ctatttcctg attcaagaaa taagaaatga ctgttcgaat
    52141 gataataata agtgcaagct tcaaaatatc tgtccaagtc ggcttgataa ctgactcgat
    52201 gatatcagca acgactagta cttccaagct taacaaaata taacttgcta gcagttttct
    52261 tgtatctgca ttacgagtat tacgttctgc atagtttttc ttgacatgag accaatcaaa
    52321 aagtttgaat agaacaagaa cgatcccgac aattaagata ccgatagaac aaatatttaa
    52381 aatagcaatg atccattcta gaaattcaat taaatttgag cgaaacatat acgctaccta
    52441 ctttctttta atttgttcct attcttttat tgtaaaagaa agttaccttg ttcgtctatt
    52501 taaaagttgt tctaatgata acggttcgct taaatttttc tttttcactc tcccattttt
    52561 ctcccctcat ccataaatcg tggaagtatc caaaacaacg tagcaagtta aaataaggct
    52621 tagtccgtca tcagcttttc aaagaagcac tgtctcggtg cttttttgta cccaaacttc
    52681 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    52741 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    52801 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    52861 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    52921 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    52981 tcgaatcaat ctagcatcct atttcgttga atcactacgg acatacttga aagacattgg
    53041 aggaatcaca atgagaaaaa gtaaatcaat aatgattggt gccggtattg ccaatatggc
    53101 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    53161 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    53221 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    53281 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    53341 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    53401 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    53461 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    53521 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    53581 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    53641 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    53701 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    53761 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    53821 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatg accaatacac tgactcaaga
    53881 agaagaacac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    53941 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    54001 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    54061 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    54121 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    54181 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctatcgt
    54241 cgtgcatcat caaccgcatt ttacgtctca gaaatcaaat gaaacagtta tttggggtta
    54301 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    54361 aaaagaaatg ctagaagaac tgatcggaca actttcaaaa gtagatcctg gaccagtgaa
    54421 tattcgtgaa aaagaaacag aaattttcga cagcgtgata aataatatcc ctgtctatat
    54481 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcggccaa aagtcattcc
    54541 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    54601 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    54661 ccctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    54721 tgccgcaaaa aaaatgtttg aataaccaag aggttgtgaa aaagctgacc tgcatcaagt
    54781 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    54841 gcagatgcaa gcttttgaac accgtttacc aagaggttgt gaaaaagctg acctgcatca
    54901 agtaataaga acacccaagc taaaacagct tcttatgttt ttgacttggt tggacttatt
    54961 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag ctgacctgca
    55021 tcaagtaata agaacaccca agctaaaaca gcttcttatg tttttgactt ggttagactt
    55081 attaccgcag atgcaagctt ttgaacaccg tttaccaaga agttatgaaa aaggcgttta
    55141 gtttcgagta tgaagaaaaa ttttgtgaaa atggttcctc acgtttttgc ataaatttga
    55201 cttaataccg agaaactgat cccttctgtc ataacctctt tttatttatg tctgtttctt
    55261 tttgaaaaca accatttttt caacgtttac tctcttgcca atccaacatc atctaacgga
    55321 tacaactatt tcaatgatta ccattacact aaaaaatcgg aaacacacct ctccgaacac
    55381 aaatacataa gactatagaa tgtttcattt aagaaaaaaa gcgtttcatt atcaaaaagg
    55441 taagatctcc tttaaaatga aattatctgt agtactaata atgcagacaa ttttatgaat
    55501 ttgaaaggag catctccaat gaaagcagtc acttggcaag gaaaacagaa aatggaaatc
    55561 agaaacgtag atgatccaaa aatattagaa ccaacagatg caatcatccg tatcacagca
    55621 acagccattt gcggctccga tctgcatctt taccatcatg gtgaagcagt tttggaaaaa
    55681 gggtatgttg taggacacga accaatggga atcgttgaag aagtgggatc tcaagttcaa
    55741 acattgaaaa aagggcaacg tgtggttatc ccttttaata ttagttgtgg tcattgtcat
    55801 ttctgcctga atcacatgga aagccaatgc gatgaatcaa atccagatca gttatatggc
    55861 gggcttttcg gatttggcaa gttgaacggt aatcattggg gtggtcaagc ggaatatcta
    55921 agagttcctt atgcagactc tacttcattt gttgtaccag ataatgttct tcctgatgaa
    55981 aaagttttat ttctatcaga tattttgccc acagcttatt ggagcgttga aaacgcagga
    56041 gtaaaaaaag gcgatacagt tgtgattcta ggttctggtc cagtcggtct attcgctcaa
    56101 aaattcgctg ttatggctgg agcagagcgc gtgatcgcag tagatccagt acagcaccgt
    56161 ctagataaag cggctaatta caatggggtt gaaacttatt tcttagaaga cacggcacaa
    56221 gctggaacag aattgtatga actggctaaa ggtggcgcag atgtcattat cgattgtgta
    56281 ggaatggacg gattagagcc tgtcaaagaa aaagcgaaaa atttagtaag cttacaaagc
    56341 ggcacaatct ctccattaca gatggcatcg caagctgtca aaaaatttgg aacagtccaa
    56401 gtaactggtg tttatatgac tccagcttct tcttacccgc tgcaagaatt ttttatgcgg
    56461 gatatcgctg tcaagcatgg acaggcacca attatccatc taatgccaaa aatttacgaa
    56521 atgatcgcag aaggactatt cgatcccaca caaatcatta ctcattcgct gccactatca
    56581 gaagcagcac aagcatatga aatctttgac aaaaaagaag ataaaaatat aaaagttgtt
    56641 ttgaaacctt gaattcagta aaaaatacag gtgattttct ttatgcccaa aatcaaacga
    56701 aatacccatg agatcgaaat aggaaaagaa gaagatatcg aaatacgagg acgtcgcttc
    56761 cgcttctatt tccaaaatcg ttacacattg atctcactgg ctgtcgattt attaaccggg
    56821 attttctata tttttggaag ccttgcttcc ttaactaaaa tccccgatcg atatggcacc
    56881 tatttttatt tggctggtgc tattttcttg acaattcgtc ctattctcag aatcgtaagg
    56941 aacattttta tttacgacga aaaaaaacaa tgaagagaac aagcaaaaaa aagaggcatg
    57001 agatttgaaa aaatctcatg cctctttttt aaccctatcg tatcactttg atacagacga
    57061 gcggtcgtcc cactttcttc cttgaccatt gtcaaaaatg tccactcgta tcgttcataa
    57121 aacgtggtat gatctgtaat taaataaagt ttttcatacc caagttgatg cattttttct
    57181 aatttccgct aatatccgct tggctatccc ctgcttacgc ttttccggtt caacaaacag
    57241 ggcacaaaga tttggtgtca gatcgggacg gttatggaag tcgttttcaa tgacgcccgc
    57301 tcctccgacg atggtttctt tttcatctaa gaccacatac cattgaggaa tactttcctt
    57361 attagcgatt ccagtacgaa tactttcctc atacacaaca gcaggaactc cccattttga
    57421 tgaaaaccac ttcgcacttt gttttactaa ttctgggtgt tctcttaatt tgatccagtt
    57481 atatgtaacc aatgtttaaa cctctgacta aaataaaacg tttacaaaaa ttatacaagt
    57541 ctttatgaaa attagcaatg acaacaatag tgatgtaaaa aaaaacggaa aacaatcact
    57601 tgttctccgt tttttgatta atcaagcatc taaagcttct tttcttcttt cttggatcgt
    57661 agctaccttg acgaacggta gatagatcaa aatagaaaga accaaattga cagcggctag
    57721 tacaccacct gcaatacttt ttgttgccaa tacaccgcca ataattggtg gagttaccca
    57781 tggaggcata acggtagctg ctggcactaa acctgtagaa gtcgcaaagt aagcaacact
    57841 aactaagacc attggtgtca aaataaatgg aatgaacatg atcgggttca acacgatagg
    57901 taacccaaac atcgttggtt cattaatatt gaagacacct ggcgcaatcg acaagtttgt
    57961 tacaaccata tatggtttgt ttttacgtcc tactaaataa atagctaaca gtaaacctaa
    58021 agttgcacct gttcctccta agttgacaaa gctgtcaaag aaaggtttgt tcacgataaa
    58081 cggtgcgcta tgtccagctg cgattgcatt aacgtttgct tcaatggctg gcgcattgat
    58141 tgtttgcatc aaaggatcga ccatattcgc tccgtgtaaa ccaaagaacc ataagaatgg
    58201 tgtgataaat gcaagcagta aggcagatgg ataagagttt gcaagtccca taaatggttc
    58261 ttggaccact gtatagaaag aacctacgat atcatcaaca ccgaatgcag caaaaattgc
    58321 agcaactaaa gcaaacgcag agatagtgat cattgctggt agtaatgaag caaatgcttt
    58381 tgcaactgcc ggtggcacac catcaggcat tttgatgatc aatttttcat ttccgcttaa
    58441 acgtacaaag atttctgttg aaataatccc aacaataata gcaataaaca aaccgtttga
    58501 gctcatacct aatgctccgc ctaaagcgaa gaaagagcct aaagaaatca cacctgcgga
    58561 aacaccgtct tttcggtagc cgttagctaa atgataagca agcaagaaag caatcaagac
    58621 agaaagaatg gcaaatgtac cgttccaagc agcagccccg aatcctttcc atgattcacc
    58681 accaaaaatt gagttcatca attcttggaa cccgggaatc ggtaagttat tgatcattac
    58741 tgctaatgct cctaagatca ttaacggcat actcaccata aatgagtccc gaatcgcaac
    58801 taaatgccgt tgtgcaccaa tttttgatgc tacaggtata aaatgtttct ccataaatgc
    58861 aacaaattta tccataaatc ttccctcttt tctttactgt agattacgcg ttcaatcgac
    58921 gatacagatc aatgatctct tttgctaaat ctgtaaaagc tatggatgtc atcagatgat
    58981 cttgactgtg gactgtcaaa agcgtgactt caacgtgatt tccttgtgct tcttgtgtca
    59041 gcatctctgt ttgagagtga tgtgcttgga ctaaagattc ctctgcatct ttgatttttt
    59101 catctgctaa agtgaaatca ccttttttcg cagcagcaat cgcttccatt gcatcgcttt
    59161 ttgcatttcc gccaaacatg atcagaccca tgatggcttc tagatttttt tgatcttcca
    59221 tttattgtat cctccgataa tttttattat ttgtttatta gtttttctgc ttggtcgagt
    59281 actttttcac cattcatcat gccatagtca gccatattga ttatatctaa aggaatgcct
    59341 ttaggtgcta gcttttcagc aaattgattt tgcataaagc gtacttgcgg tcctaaaagt
    59401 aaaacgtcta catttttaga ttctagttga ttatccgcat ctgaagcaga tacagcaaag
    59461 atgtctgctt ccattccttt tgcttctgct gccttttgca tttttgtgac taggagactt
    59521 gtactcattc cagctgaaca tacaagcatg attgttttct tttccatttt aaacacgttc
    59581 ctttctatac ttacacttgt atataagcaa gtagcgtgcc aactttaaaa gcgctttaaa
    59641 aagttgatat catcacattt aaggtctata ccaagttgca tacacactaa aaaagaaagt
    59701 gcacactaaa cacacaaatt aatttttatt accttttttc ttttaacgtg cacaaaaaaa
    59761 gttgtgacac aaaacttgtc acaacttttt ttcgaataaa cggtattcaa aagcttgcat
    59821 ctgcggtaat aagtccaacc aagttaaaaa cataagatgt tgtttttact ttgctattct
    59881 tattacttga tgcaggacag ctttttcaca acctctcaat aaacggtgtt caatcagctg
    59941 accctggatt ttagctcaaa acgctggatt cacaacctct tttatttcaa ataaccagta
    60001 aatacaatga acatctacaa aaaacttcta tttatttata gatttcgtca ggcaaatcca
    60061 attctctctt atcaatcaaa gtctgatacc acgaagcaga ttttttcaat gttctgcttc
    60121 gttcatcgtt caattcgatt cgaactaatc catatcgatt cttaaatgca ttcattggtg
    60181 acacacagtc agtgaatgcc cataacatat agccttcgca atttgcgcct tcttctgttg
    60241 ctttgatcaa ataacgcaaa tgctgtccga taaattcgat acggtaatca tcttgcacga
    60301 ttcctttctc atccatatac cgttcttcat gttctcttcc cataccgttt tctgttatca
    60361 gccaagggat attatgataa ttttctttta gatacatggc tatatcatac atgattttcg
    60421 gatagatttc ccatcccctg gaattattca ttttcttccc aggtaaatca aagacttcat
    60481 aatatcgttc tggatggaaa ggtgtctctt cattccattg ataacgagga gcgcgaacgc
    60541 gtttaggata atattgattg attccaagga aatctactgt atgatgctga atcgtttcta
    60601 aatcctctgt tgcaggatcg aaataaatcg attgtttttg acacaactcc aggaactctt
    60661 ctgtgtagta cccttttacc atcggatcaa aaaatactcg attataaaac aaatcataca
    60721 tataagcagc tttttggtct tctggagaat tagatcgagc atagaccatt tcaggattta
    60781 aaatacagcc aatccttcca ccataatttc cgctgcggta aatctctact gctttagccg
    60841 ttgctaaaac tttatgataa ttccacatca tccacttttt tgtgttttgt tcatgcggcc
    60901 agcgaacagc atccaaatag caacgcgttt ggggaacgat tggttcgttg aatgtaaacc
    60961 agttttttac cctatcaccg taacgatcaa aggcaatttg agcatactta gcataaaaat
    61021 caactacttt tcttgaagac cagccatcat atttttccaa aagaaaagct gggacttcat
    61081 aatgttccaa acaaatcatc ggttctacgt ctgcttcgat caaagagtcg atcatttcac
    61141 ttatatgctg agcatattct tcatctacta tacagttctc ataatcagta aaaaaacgag
    61201 cccaattgat agaagtccga taatgtgtca gatggatgga tttcatcaga tccacatcct
    61261 gctggtattg ttccataaaa ttagttgcta cggctgggcc atacccatta tgccaaacaa
    61321 aatgttcatt tttataccag ctatctataa acgaatcctg tccttctttt tttcctttcc
    61381 aaccttccgt ttgccaagca gaagatgcag caccaagaat aaaatttttt ggaatagtaa
    61441 ttttcatgat ttcctcctgt ttttagatcc catcattttc cacacgattt gctactttta
    61501 caaatggcag atagatcaaa atagaaacaa taatacaaac aagttgcgta ataactgcac
    61561 cgatatttcc tgctgttgcc agataagcat tgacgatcgg cggcattggc caagggacca
    61621 ttacaactgc tttcgccgca aaccctaaag cggttgcaaa ataaccaatc gttcctgtga
    61681 taagaggcgt taagataaac ggaatagcta aaattggatt cagcatgatc ggcataccaa
    61741 aaataactgg ttcattaatg ttgaagatcc caggagcaag ggataacttg gtgatttgtt
    61801 tcatatcctc ccgttttcca actaacaata ctgcaatcag taaaccgatc gtgactccag
    61861 acccacccat actcatatac atatcccaaa atggcatagt aataatgttc ggtacttctt
    61921 ttccagcttc aaaagcttcc gtatttacag caattgccgc taaaagcaac ggttcccgta
    61981 tcggcttcac catttgattt ccatggatac caatcaccca aaagacttgc gcaataaaca
    62041 tcaatagcaa aatacccggt aacccttgaa cgacaccttc taatgggcgt tgtacgacat
    62101 tgtaaatgat atcataaagg tacattcctg taagttcttt gatgataaat cccgcagccg
    62161 cgatacccga tacagtcaga atcgtcggga ataaagcaga aaaactagca gaaacattcg
    62221 ttggcacggt atcaggcatt ctcagctgta gtttcttctg tttcctcaac cagcaataaa
    62281 gttcaataga aaggatggag accaacattc ccaaaaataa ccctttcgtg tctgtatatt
    62341 gtttagccaa tacgttttct actataacag tctgattttc attcactaat tcataaacag
    62401 ttggattaac agataaataa gacatcactg cgatgatacc agggaataca ccatccactt
    62461 tattcagctt ggctaattcg atccctatta gaaaaacagc atagatggtc aagaaactta
    62521 gtgtgacata gctgatggca gatgcgatag gctttaattc ttctaaaaaa cgcaagtaac
    62581 ttatctgtgc taagccattt tccgagtcaa agaccattgc tgaaaacaat gtgccaaaag
    62641 cacccgtaat aattaccgga atcaatgcag caaatgcgtt ttttatcacc atgatatacc
    62701 ttaaattatt gattctcgtt gccacgttcc ctaaaacttt ggctaattta tccataaaac
    62761 tcattccaga tcccctcatt cctgcttctt ctccttgacg tcatctcttt ttgtctatta
    62821 gtcagcgctt acattttggt gaacagaaac tatttactcc tcttttttac caaatataaa
    62881 acaaaaaatc atctgatgta tttatcataa aatacatcag atgaactgtc aattagtttc
    62941 tttttctcct attattttct gtaattctct ccgatttatt gccatatgga cagtcattgc
    63001 gtcaaacgca gcaagtacgt tccgcctttc gatggcctga acgatctctg tatgaatatc
    63061 gatcgtctcg attttcagat gctggatatc ataattttta ttaaacaaag caatcgattc
    63121 attaatgatt gggataatat gcagcaaggc tatgtttccg ctagcttctg caatcatcgt
    63181 atgaaaatcg atgtctaatt gaacatgttc ttgtgtgcct tctcgaaaag aagtttcaat
    63241 cttttgcgtt aattttttca tttggacgat ttgattcttc gttgcatatt ccgctgccaa
    63301 acctgccatc ttaggctcca ataaatatct cagttcaaat aagtctcgta tcatccgatc
    63361 ctgatcttca atcaaagaaa aaccgagtgg gtcattggca atccctcgct tatcactgac
    63421 aaatgtcccc gctccttgcc gaacttcaag gatattcctg gaagctagag cccgcacagc
    63481 ttctcgcacc gtgcttcgcc ccacctctaa ataatcggac aattcatatt cattcggcag
    63541 tttatctcct acttgcaact gcatttcctt taaatatcta aggatcttgt cagtagttac
    63601 ttctactagg gttttatttt cttccaaacc acatacctcc ttttcatctg atgtattttt
    63661 tcgtaattat tataacacgt ttgaatcatc tgatgatttt ttgtataaaa aatcgattaa
    63721 tccgttcata gacatacaaa cgaagaagat atttaccata aaaaagacta ggataaaatt
    63781 cactcctagc cttcgatcat ttttattttg atcgacaaaa aatatgatgt tcaataacag
    63841 acgatcttca ttcgattctt gatgtcatct tttgtttttt ttaatatatg gataaaaagt
    63901 ttgattacat cgtttctatt ctagaatttg gtcgattctc aattcttctt ctggtgagaa
    63961 atctaaatta tccatcattc gaacactttc ttgtaactga cttaaccgac ttgctccgat
    64021 cagtacactt gtaacagatt tttgtcgtaa attccatgca agggctattt gcgctaatga
    64081 ttgtcctcgt gatacggcga ttgtttgcag tgctttgatt ttttccagag ttgatccaac
    64141 ttgttcttct gaaaggaatg gtatttcctt acgatgtgct ctagaatctt caggaatacc
    64201 atgtagataa cgatttgtca gcaacccttg agcaagcgga ctgaacgtga ttgcccctag
    64261 cccttcttct tctaatactg gagatagatc gtcttctagt agtgcacgag aaaacatatt
    64321 gtagcgcatc tgatgaataa tgaacggtgc ttcctttctt tttaaaattt cagtcatttt
    64381 tttgtatctt ctccattata gttggatata ccaatatata atgcttttcc ttgtcttaca
    64441 agttgcatca acgcttctgc tgtttcttcc aaaggtgtat cagggtctgg gcgatgatga
    64501 tagaagatgt caacataatc tagccccatt ctttggaaac tttggtcaca acttgatatg
    64561 atggatttac gagagcccca ttccccatat ggcccttccc acatatgata acctgctttg
    64621 ctagaaataa tcagttcatc acggtaggct tgaaaatctt ctctaaaaat acgcccaaag
    64681 tttttctctg cagctccagc agggcctcca taattattcg caaggtcgaa atgggtaatt
    64741 cccatgtcga atgcgcctct taaaatctct ctttgattat ggataggatc ataatcacca
    64801 aaattttgcc ataatccgag aggagagata aaatcggtaa tttcaaacct gaatgaccgg
    64861 atttacgata ttccattttt tcataacgtg cactatctgc aatatacaat ttttctcctc
    64921 ctcatcaaat ctttttaaaa cgctttcttg ttttctattt ttagtttact acattttaaa
    64981 gaaaaggagt taatcaaaat gattttttcg tatatttttt tgccatttgt tttttactcg
    65041 ttgatagatc agaaattgat tacgtgcttg ctggattttt ttatagcgtt tcggttgttt
    65101 tttgtaaaat tgctgatgat agttttctgc tggccaaaac gtaccggctg gttcgatttt
    65161 tgtgacgatt ggttggtgga aagttcctga actgtctagt ttctgttttg attgttccgc
    65221 taattctttt tgtcgttcgt cttgataaaa aatcactgga cgatattgct tccctctatc
    65281 ttgaaattgt ccaaatgtat ctgtgggatc agtaatttgc caatagattg tcagcaactc
    65341 gctataactt atttctcttg tgtcataaat gatctccaca gcttccacat gacctgtgta
    65401 accaccactt acttgatcat aattcggttt ttcaacatgt ccgcccgtgt atcctgacaa
    65461 aacagatagg atcccttttt tcgattcaaa cggctcgacc atacaccaga aacatccccc
    65521 tgcaaatact gcacgttctt gatagtcagc atcttgcatg gcatgcttgg aaaagtcata
    65581 tttttgctcc ttatcaaatc cttccgtaat caataaataa aagtccatta catcaggcgt
    65641 cagattcatt cggatagcta atggacgtag tgttacttct agttttgata actgttcttt
    65701 aacggatata ttttctcttg tgtcattctt tgtctgaatc aatacttttc gttcccaatc
    65761 tcgtgtattc ggattcaaaa tcagattata aagtgtttga atgaatattt gttcctcatc
    65821 catagattct cctcctttcc gaagaagaca agctagtgac tttagctgta atttatcata
    65881 aagtgaggaa ataatcgatt gaatcgtatt tattcaaaga agataagcag cttcagatga
    65941 tataagatga tctttatctt aaaaagcata ctctatggtt tggtttaact aaaaaacgac
    66001 ctctgaaaaa agggatgttc tccaattctc agaagtcgag taaagatgat tcttttttat
    66061 gagcgataat aaacttcatc caaaaacaga ccttgtgcag ggacggtttc tcctgcatgt
    66121 tgccgcactt tgctttcaaa tatttcatcg attgtttcta tcggcatggc acctgtgccg
    66181 atttctagta atgtccccat gataatccgc accattttat ataagaatcc gtctccgaca
    66241 aaagtaaaat gaagcatttc tccctttcgt tcgatagata attcatcaat cgtacgcact
    66301 gtggattttt ttgatttttt caatgcagaa aaaccaatga aatcatgtgt acccactaat
    66361 ttttcgcaag ctgcattcag cttgtccata tccaactctt gagggaaata aaagctgtgg
    66421 tttcgctcaa atgctgaagg aatcacgttg ttccaaacat aatagctgta ttttttgccc
    66481 accgcattat atcttgaatg gaagcgctca ggcatttctt cgattctttt gatgacaata
    66541 tcccgcggaa ggtaacgatt cataaagtcg atcatttctg ccagtccaat ttctgtgttt
    66601 gttttaaaat ttgctacttg tcctcgcgca tgggtgccag catctgttct tcctgatcca
    66661 ataatttcta tctcttcatt tgtcatctga tgcaatactt tttcgatttt tccttgaatg
    66721 gttttatcgt catctccaag tctttgccat cctgaatatc tttttccgtc atattcgatt
    66781 gtcaacttga tgtttctcat attttagtgg ctcctctgtc ttccatttgg tcttctctct
    66841 acctttttaa gattgtagca caaaatatag ctccttgctt ctctaagaca gaagctatac
    66901 aagaaaactg tggaaatata tatttcagaa aaacaaaaaa cagccaccgg atgaagtatc
    66961 cgctgactgt tcaatttgac ggctcaagtt ttactgtttg agatgcaaga tactcaacca
    67021 ggcaatgggc acataattaa agaaaaaact gattctttgg caaaaaccta ttttattcag
    67081 taatggccaa gaatttatag aaggaattct tgccagtcca taaatcgccg caaaaagcaa
    67141 actgatcaca gacagtccaa ggtataagtg gcttacgtcc atttgcccat tttttcgata
    67201 gatcaagaaa agaagaactg gaaacaataa aaaaccactg taacctaaac ctgatccgat
    67261 attatggacc catgtcgaga cattccacga agattcatgg gtattgatac tgaacaaacc
    67321 tgtaaagata caatcaccta taccatagaa cgcgatggct gctgtaacta gggtagctaa
    67381 cacacgagat gtacttacaa atgcagcata caatgcaggc aatgacagga tgaaaaagat
    67441 ccctgaaacc acagaccaaa taagaaacgc ttttcttaca ggactggaaa cctctccaaa
    67501 tacactgatc acgctcttca tttgatctaa ttcaggataa tacaatccta atacgtacgg
    67561 agtcaaaaaa tcactcagca cgcctaataa taaaaagaaa aaaccaaatt tacgtaaaaa
    67621 atccatgata cgcctccaat aacaattacc tatgctttta attgttatta taaacgactt
    67681 tatcttgatt taacagaaac ctctatttac acgaacatct atataactca ttaaaaactc
    67741 gaatcatttt aaaaatacta aatatctaac gttcaacgtt cacttaatcc atctaaacaa
    67801 tctttcaatt tgattttttc cccacttctt ttacgcgcgc ctagctctcc tattgcagta
    67861 aacaacagat cacttgacga atttaaggca gtttccattg aatcctggat aacaccgata
    67921 ataaatccaa taccaacgat ttgcatcgcg acatcattag agataccaaa caaactacat
    67981 gctaatggaa tcaataacag tgaaccgccc gcaacacctg aagctccaca agcagctaaa
    68041 gcagacaaaa tacataaaag gactttcaaa acaaatggtg cttcaatccc taaagaatgt
    68101 acagcagtca acgtcatcaa ggaaatggta atcgcggcac cgcccatatt gatcgtagca
    68161 cctaacggga tcgatatgga ataagactct tttgtcaatt tcaatctttc agccaacatc
    68221 atgtttatcg ggatatttgc ggcagaactt cgggtaaaga aagcgggaag tgcgctttct
    68281 ttcaaacaaa agaaaatcaa tggataggga ttttctttaa taaacaaaaa cgtgaggaat
    68341 gggtacacaa ctaatgcgac aaacagcatc gtaccgatca aaacaagtaa aagctgcaga
    68401 tactctgcca atccagcgat tccagtcgta gcaattgatt gataaaccaa tcctaaaatc
    68461 cctatcggag caaatgcaat aatcacttgt acgacttgtg acaacgctat agatatctga
    68521 tccaccaact cttttgtcga ttctgaacgt gctcgaaaag ctagtcccaa caatacagcc
    68581 cagaataaaa cgccaaggta attcgcatca ataagagatt gaacaggatt ttgtgtgaca
    68641 ttcgtcaaca tagtagataa aacactttcc aaactttgcg gtgctttttc agatactgtt
    68701 tcttgtaaag taataggaac agtaaaaatt gaacttacaa tgactgctac aagtgcagaa
    68761 agcaatgttc ccactaaata taagatcaaa ataggcttca cgaatgtctt attcccaatt
    68821 ttatgcttgg caattgacgc catcgtcaag aaaaaaacca gaataggtgc gattgccttc
    68881 aagcaactga caaacaacgt ccccaatatt gaaataaatg tccacgtggg gaaaaagata
    68941 ccaaacaata ttccgactaa aataccaaca acaatacgtt gaactaacga catatccaaa
    69001 aacttctcta acaaatgacc accctttcac aattttaaca atcattgtat cattttatct
    69061 aaagaaacta aaggtgcaat tttctaaaaa ttctaataat acaattggca attcatgctc
    69121 ttgcaacatt caattttagt attggagggt ttattcaatc tctaaagaag tcgagagaaa
    69181 actatttatc gttattatta tagttatcca agtaaaacgt aactaagatg aaggacgaaa
    69241 ctagaaattt catccttcat cttaattctt agacatagca atcaattaat attttccact
    69301 gagtctcttc tttctctcac tctcactggt ttacttaccc ataaacgatt tgattaaagc
    69361 catttttcaa ttcattattc gctgtctcgt taaagtaaag ataattatcg ggattcccct
    69421 gattttgttg tgtcaccaat acttttggct gattttgctg aaacccgaat agatagacgt
    69481 tctttttcag atatggttct gtctctgcat cggaatagac ggctgtgatt tgatagtctg
    69541 cttgacctgt cccactttct gaccattctg cagaaacagg cactccacca atagccatct
    69601 tccactcccc gttcaaaata acttgaggga ctttaagacc atataagtcc acactcattt
    69661 gattcgtata gcttttgtat tgttgtccca ttgtttggcc ccatgtagcc ataaatgcct
    69721 ctaattgtgc ggatttgtct gcattccaca gtgtttgttc gacttgttcg ctgctttctg
    69781 aagatgaagc ctctacagaa gaacttgaag tagatgtttg agttgtttca gtcgttttgg
    69841 aagactctga cgaagtagag gtatctgctg tttccgtact tgctgcagtt ggcttgctct
    69901 ctgtgctagt tgttgtagta gttgcaattg ttgctttcgc tgtttctttt gttgattctt
    69961 ttttcgattc attcccgttg gtacaaccag ctaacaaaaa agctagacca attgttacta
    70021 aaatcctttt tttaaattaa aaaactcctt tcgattactc ccacttcttt attctatcaa
    70081 ataagcaatg tgattttatt gattttttgt attttctcat ccatctttta aaccttttaa
    70141 aaactaagaa gcacccgctg atgttgtctg taatacatca gcgggtgctt cttttatttt
    70201 aatcttcgtg attttccaat ttacctcacg ctttatattt gtatttgaag aaacatagac
    70261 ttttagtcat catcgtcttc ctcatccaaa tcttgtcgga cagtttttcc ttggagtctt
    70321 tgtacttggt agatgatttc tttattgaaa cttaaaagtt caacaagcaa ttgtttcaag
    70381 ccatattttt cttctttttc agctaatttg attgcccgtg tgataaagac attttggaaa
    70441 tcaaaatctt ttgcaaagtt ttccaacatt gttgaggctg gtaaatattt gttttgacca
    70501 tgttcgtaaa tttttccata acgcatgact tcttctaaag tagacggaac gatttcattt
    70561 tcaatcacta actcatgaga gattttattg aaccatctcg cttcttgatc agcatattct
    70621 gaaaaaaggg tacttaattc ttgcgaagat gtacccaaaa catacaattg tgcttggatc
    70681 aatttcattt cttctaattt aaaatttgcc aatacatgcc ccaccatggc gccagcagtt
    70741 ggtttatgat gatcgatatc tgcttgtttt gtttcttgag caaatttttc ttccactata
    70801 ttcactgatt tacgcctctt ttacttttgt tgattggact tcataaccta atttttccac
    70861 aactgcagct aattgttcag ggtggacttc atctggatca aagtttgctt tgattttgct
    70921 cgcattaaac aaaactttcg tattgcttac cccaggctgt tgagaaaccg catgttctat
    70981 tttttgcata cagcttggac aagctagtgt atctaattgc ataatcattt ttttcatcgt
    71041 agttcttcct tcctttttct tgatagtctt attctagatt acagcttcca taaaaaaatt
    71101 gattcttatc aagttttacg atttttcttc tttgctttcg tgtccaaaat acaataaacg
    71161 catcgcgtta aagataacga tcaagatact agcttcgtga acgaacatcc cactagccat
    71221 gtaaataaac ccggcaaata agccgatgag taaaaataag acgacaccaa tggcaatcac
    71281 tacattttca cgggtattca aaacagtttt cttagccaaa cggtaagcat gaaccaacga
    71341 tccaaaacta gattgcatca agacaacgtc actcgtttcg atagcgacat ccgttcctga
    71401 tcccatagca atcccgatat cagccgcagc caaagaggga gaatcattga ttccatctcc
    71461 aatgaaagca acgtgcaatc cttgttcttg gtattttttc acaaattgaa ccttttcatc
    71521 tggcaataat tcagcatgga cttcatcaat gcctaacata tcagctacat aatcagcagt
    71581 catctgatta tcacctgtca gcatcactaa atgttttgct cctgcttgtt tcaacatagc
    71641 taattgttca gcgacttctg gtcgaatcac atctgacaca ccaatgattt gagtgatttt
    71701 tttgtcgatt gctacaataa tgactgagct gcctctttgt tgtaattgat gtaaatcttg
    71761 tacttgcttt ggtgtgagag aaagtttgtg agcggcaatc aatttggtgt tgcccgcaca
    71821 aactgtatga ccatcaatct cagctgtgat tccttgtccc ttgatcgtct gattatcttt
    71881 gactgctaat tgttgaaaat caatgtcttt ctcctgagca taatggatca cggcgcgccc
    71941 cagaggatga tcggataacg tttctaatcg agccactaaa gctaagctgt ccccttcatc
    72001 ctctgtatag ttcttgatag tggatacagc agtagttcct ttggtcaatg taccggtttt
    72061 atcaaagaca aaagtatcga ttttggaaaa agtatccatt gcttcaccgc ctttgactaa
    72121 gatgccccgt ttcgctccat taccgattcc tgctacattc gaaacaggcg caccaatgac
    72181 taaagcgcca ggacaaccaa gaaccaaaac agtgatggct aaacgaaaat cacgactgat
    72241 cagaccaaca agcaacgcaa taagtaaaac ggttggagta taatactgag aaaattgatc
    72301 aatgaatttt tccgcatgtg atttggtatc ttgtgcttct tcgactaatt ctataatttt
    72361 ggcaaaggtc gtatcatctc cgaccttagt tgcttcgatc gtcacgtagc catctgctaa
    72421 aatcgttcca gaaaatacgt tatctccact gattttgacg acttgtcgtg attcacccgt
    72481 cactgcggct tcatccgcat accctttccc gtcaatgact cgtccgtcca caggaatagc
    72541 tccaccagtt tttactaaga cgatatcgcc ttcttccacg tcatcgattt ccacttcttc
    72601 ggtcgttcca tcttcttgga caacgctggc agtcgatggg gccatctcgg tcaaagcctt
    72661 gattgattcc cgcgttttgg tcaatgtttt ttgttccaga taactaccaa acaaaaacaa
    72721 gaatgtaacg atagctgact ccttgtattc tccgatcata aaggcaccaa gcacagcaat
    72781 agtaacgagt aaatcaattg agataacttt gacttttact gcctgatacg catggattat
    72841 aataggtatg accgcaataa tagaagctat ggctagagca atgttataga acaagacaaa
    72901 tccagtaaat ttcccgataa aaccaaaaat aatcaacaca gctgataagg cggtgatatg
    72961 atttcgatgc tcttggatcc acttttgtaa tttcatcttt ctccctcttt tccttttcat
    73021 tcttacgaga ctaagtatag atacttatcc atcataaaaa attgaccact atcaagttta
    73081 ttcaaaaagg cggttttctt ttggtatact gaattcctac agtcattaaa cgatcatata
    73141 gaaaaaggaa gcgccgaaac gcttccttag gtagttctat ttttttattc aaagataaga
    73201 tgctttgtca tcttacgact gaagaacaac aatcaaaaaa gggcagcagc cactcattca
    73261 caagaaatat cgttttttga tatgggaatt gaagcagtgg acaaatatct ctacttatta
    73321 gctgggaata agatccaaaa aagcttaatg gattttatcc aagaattgga atgtactttc
    73381 cacaaaaaat tcactcattc cattctttta aaacttttga ttcatacagc gtgtctaatt
    73441 gagcgtacat tgataaacgg tcatgaactt aaaattatat cagaagatga cacaagacct
    73501 tctcatgaaa caatttttca tgtaaaaaag gccttcaaaa atattgaaac agaatttggg
    73561 atcactgttt cttatgatga atgtttcttt atctatgata ttatcgcatc taaataatct
    73621 ttttttatgt aaacgagtat ttttttaact tattgtttaa gagtgatacg cgaattgtaa
    73681 aattaagtta gaaaaataaa aaggcattta tggtacactc aaattgtatt tccgacgaaa
    73741 gaaaacaaag gagtgt
//
LOCUS       DAIGTA010000005        72433 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.005, whole genome shotgun sequence.
ACCESSION   DAIGTA010000005 DAIGTA010000000
VERSION     DAIGTA010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.005"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(159..443)
                     /locus_tag="NOB43_000323"
     CDS             complement(159..443)
                     /locus_tag="NOB43_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981221.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(461..1351)
                     /locus_tag="NOB43_000324"
     CDS             complement(461..1351)
                     /locus_tag="NOB43_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCI0981222.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1371..1589)
                     /locus_tag="NOB43_000325"
     CDS             complement(1371..1589)
                     /locus_tag="NOB43_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HCI0981223.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1559..3259)
                     /locus_tag="NOB43_000326"
     CDS             complement(1559..3259)
                     /locus_tag="NOB43_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCI0981224.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3526..4299
                     /locus_tag="NOB43_000327"
     CDS             3526..4299
                     /locus_tag="NOB43_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981225.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="NOB43_000328"
     CDS             complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="NOB43_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HCI0981226.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5015..5117)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5123..6094)
                     /locus_tag="NOB43_000329"
     CDS             complement(5123..6094)
                     /locus_tag="NOB43_000329"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI0981227.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="NOB43_000330"
     CDS             complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="NOB43_000330"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCI0981228.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8064..8882)
                     /gene="purR"
                     /locus_tag="NOB43_000331"
     CDS             complement(8064..8882)
                     /gene="purR"
                     /locus_tag="NOB43_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HCI0981229.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9049..9873)
                     /locus_tag="NOB43_000332"
     CDS             complement(9049..9873)
                     /locus_tag="NOB43_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0981230.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9846..10526)
                     /locus_tag="NOB43_000333"
     CDS             complement(9846..10526)
                     /locus_tag="NOB43_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0981231.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10549..11487)
                     /locus_tag="NOB43_000334"
     CDS             complement(10549..11487)
                     /locus_tag="NOB43_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HCI0981232.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11732..12595)
                     /locus_tag="NOB43_000335"
     CDS             complement(11732..12595)
                     /locus_tag="NOB43_000335"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCI0981233.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="NOB43_000336"
     CDS             complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="NOB43_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI0981234.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFLSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15451..16257
                     /gene="proC"
                     /locus_tag="NOB43_000337"
     CDS             15451..16257
                     /gene="proC"
                     /locus_tag="NOB43_000337"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCI0981235.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16336..17892)
                     /gene="rny"
                     /locus_tag="NOB43_000338"
     CDS             complement(16336..17892)
                     /gene="rny"
                     /locus_tag="NOB43_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HCI0981236.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18303..19352)
                     /gene="recA"
                     /locus_tag="NOB43_000339"
     CDS             complement(18303..19352)
                     /gene="recA"
                     /locus_tag="NOB43_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCI0981237.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19461..20702)
                     /locus_tag="NOB43_000340"
     CDS             complement(19461..20702)
                     /locus_tag="NOB43_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HCI0981238.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="NOB43_000341"
     CDS             complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="NOB43_000341"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCI0981239.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21729..22652)
                     /locus_tag="NOB43_000342"
     CDS             complement(21729..22652)
                     /locus_tag="NOB43_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0981240.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23391..24677)
                     /locus_tag="NOB43_000343"
     CDS             complement(23391..24677)
                     /locus_tag="NOB43_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI0981241.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24670..25938)
                     /locus_tag="NOB43_000344"
     CDS             complement(24670..25938)
                     /locus_tag="NOB43_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI0981242.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26190..26651
                     /gene="mscL"
                     /locus_tag="NOB43_000345"
     CDS             26190..26651
                     /gene="mscL"
                     /locus_tag="NOB43_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCI0981243.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26710..27156)
                     /locus_tag="NOB43_000346"
     CDS             complement(26710..27156)
                     /locus_tag="NOB43_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0981244.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(27249..27494)
                     /locus_tag="NOB43_000347"
     CDS             complement(27249..27494)
                     /locus_tag="NOB43_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HCI0981245.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(27609..28187)
                     /locus_tag="NOB43_000348"
     CDS             complement(27609..28187)
                     /locus_tag="NOB43_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0981246.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(28264..28794)
                     /locus_tag="NOB43_000349"
     CDS             complement(28264..28794)
                     /locus_tag="NOB43_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HCI0981247.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(28798..29658)
                     /gene="rlmB"
                     /locus_tag="NOB43_000350"
     CDS             complement(28798..29658)
                     /gene="rlmB"
                     /locus_tag="NOB43_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCI0981248.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(29651..30046)
                     /locus_tag="NOB43_000351"
     CDS             complement(29651..30046)
                     /locus_tag="NOB43_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HCI0981249.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(30043..31455)
                     /locus_tag="NOB43_000352"
     CDS             complement(30043..31455)
                     /locus_tag="NOB43_000352"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCI0981250.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(31452..31988)
                     /gene="cysE"
                     /locus_tag="NOB43_000353"
     CDS             complement(31452..31988)
                     /gene="cysE"
                     /locus_tag="NOB43_000353"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCI0981251.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(32074..32313)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32310..33770)
                     /locus_tag="NOB43_000354"
     CDS             complement(32310..33770)
                     /locus_tag="NOB43_000354"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCI0981252.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(33940..35097)
                     /locus_tag="NOB43_000355"
     CDS             complement(33940..35097)
                     /locus_tag="NOB43_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HCI0981253.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(35131..36501)
                     /gene="radA"
                     /locus_tag="NOB43_000356"
     CDS             complement(35131..36501)
                     /gene="radA"
                     /locus_tag="NOB43_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCI0981254.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(36564..37091)
                     /locus_tag="NOB43_000357"
     CDS             complement(36564..37091)
                     /locus_tag="NOB43_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCI0981255.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            37321..38127
                     /gene="proB"
                     /locus_tag="NOB43_000358"
     CDS             37321..38127
                     /gene="proB"
                     /locus_tag="NOB43_000358"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCI0981256.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            38124..39371
                     /locus_tag="NOB43_000359"
     CDS             38124..39371
                     /locus_tag="NOB43_000359"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCI0981257.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            39447..39791
                     /locus_tag="NOB43_000360"
     CDS             39447..39791
                     /locus_tag="NOB43_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981258.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(39908..40234)
                     /locus_tag="NOB43_000361"
     CDS             complement(39908..40234)
                     /locus_tag="NOB43_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981259.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(40607..41808)
                     /locus_tag="NOB43_000362"
                     /pseudo
     CDS             complement(40607..41808)
                     /locus_tag="NOB43_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            41925..42440
                     /locus_tag="NOB43_000363"
     CDS             41925..42440
                     /locus_tag="NOB43_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0981260.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(42639..43085)
                     /locus_tag="NOB43_000364"
     CDS             complement(42639..43085)
                     /locus_tag="NOB43_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI0981261.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(43132..44610)
                     /gene="msr(C)"
                     /locus_tag="NOB43_000365"
     CDS             complement(43132..44610)
                     /gene="msr(C)"
                     /locus_tag="NOB43_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI0981262.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(44964..45593)
                     /locus_tag="NOB43_000366"
     CDS             complement(44964..45593)
                     /locus_tag="NOB43_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0981263.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(45577..46041)
                     /locus_tag="NOB43_000367"
     CDS             complement(45577..46041)
                     /locus_tag="NOB43_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0981264.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(46528..47796)
                     /locus_tag="NOB43_000368"
     CDS             complement(46528..47796)
                     /locus_tag="NOB43_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0981265.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(48027..48764)
                     /locus_tag="NOB43_000369"
     CDS             complement(48027..48764)
                     /locus_tag="NOB43_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0981266.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(48831..49400)
                     /locus_tag="NOB43_000370"
     CDS             complement(48831..49400)
                     /locus_tag="NOB43_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI0981267.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            49528..50400
                     /locus_tag="NOB43_000371"
     CDS             49528..50400
                     /locus_tag="NOB43_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0981268.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            50742..51614
                     /locus_tag="NOB43_000372"
     CDS             50742..51614
                     /locus_tag="NOB43_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0981269.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            51611..53569
                     /locus_tag="NOB43_000373"
     CDS             51611..53569
                     /locus_tag="NOB43_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0981270.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(53820..54671)
                     /locus_tag="NOB43_000374"
     CDS             complement(53820..54671)
                     /locus_tag="NOB43_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0981271.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            54794..55261
                     /locus_tag="NOB43_000375"
     CDS             54794..55261
                     /locus_tag="NOB43_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCI0981272.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(55524..56006)
                     /locus_tag="NOB43_000376"
     CDS             complement(55524..56006)
                     /locus_tag="NOB43_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCI0981273.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(56106..56969)
                     /locus_tag="NOB43_000377"
     CDS             complement(56106..56969)
                     /locus_tag="NOB43_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0981274.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            57567..58415
                     /locus_tag="NOB43_000378"
     CDS             57567..58415
                     /locus_tag="NOB43_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981275.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(58586..58927)
                     /locus_tag="NOB43_000379"
     CDS             complement(58586..58927)
                     /locus_tag="NOB43_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCI0981276.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            59013..59720
                     /locus_tag="NOB43_000380"
     CDS             59013..59720
                     /locus_tag="NOB43_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI0981277.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            59707..60030
                     /locus_tag="NOB43_000381"
     CDS             59707..60030
                     /locus_tag="NOB43_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI0981278.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(60119..61156)
                     /locus_tag="NOB43_000382"
     CDS             complement(60119..61156)
                     /locus_tag="NOB43_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0981279.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(61603..62586)
                     /locus_tag="NOB43_000383"
     CDS             complement(61603..62586)
                     /locus_tag="NOB43_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HCI0981280.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(63002..63772)
                     /locus_tag="NOB43_000384"
     CDS             complement(63002..63772)
                     /locus_tag="NOB43_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981281.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(63765..64700)
                     /locus_tag="NOB43_000385"
     CDS             complement(63765..64700)
                     /locus_tag="NOB43_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981282.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(65294..66943)
                     /locus_tag="NOB43_000386"
     CDS             complement(65294..66943)
                     /locus_tag="NOB43_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI0981283.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(67138..68034)
                     /locus_tag="NOB43_000387"
     CDS             complement(67138..68034)
                     /locus_tag="NOB43_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0981284.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(68027..68707)
                     /locus_tag="NOB43_000388"
     CDS             complement(68027..68707)
                     /locus_tag="NOB43_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0981285.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(68708..69490)
                     /locus_tag="NOB43_000389"
     CDS             complement(68708..69490)
                     /locus_tag="NOB43_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981286.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(69483..70400)
                     /locus_tag="NOB43_000390"
     CDS             complement(69483..70400)
                     /locus_tag="NOB43_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0981287.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(70403..70687)
                     /locus_tag="NOB43_000391"
     CDS             complement(70403..70687)
                     /locus_tag="NOB43_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981288.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(71388..72008)
                     /locus_tag="NOB43_000392"
     CDS             complement(71388..72008)
                     /locus_tag="NOB43_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981289.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(72089..>72433)
                     /locus_tag="NOB43_000393"
     CDS             complement(72089..>72433)
                     /locus_tag="NOB43_000393"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981290.1"
                     /translation="SNIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQD
                     KKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQK
                     KRDNNDQYLPKK"
BASE COUNT        20831 a        15442 c        12751 g        23409 t
ORIGIN      
        1 ataccgagaa aatggttttt gaacatcact tattcaaaat aaaaaaagat tgtgacacga
       61 attttgtcac aacctttaaa tgtattccta gagcaaagaa gctaagcgaa gaaatccaat
      121 tctgattatt tattgtattt ctttgttcag catccttgct aaaagcccat attggacaaa
      181 gtattcacta cacccatgat ctcatctttt cgagaacgtg ctttttctgt cggatcttct
      241 acctcttctg tgtcaattcg aacaataaat ttccgattca tcgtcacgta agcaccgtcg
      301 ttgatcaaaa taaacagttc gttctcatta tagtctgcac aggcatcttt ccatacgtca
      361 aagccgtttt tttcagaagg gatatcccgt ttaaccacag tttttccact taattcgtgg
      421 aacgttacgt cataatattt cattatctct acctctttcg tcattcaata ttttgtactt
      481 gttctctgat tttttctaag atcgtcttag actggacgac ttgattttta atttcgattg
      541 catttgattt ggaaccgatc gtgttgattt cccgattcat ttcttggatc aggaaatcta
      601 attcccgacc tacaggacat tgtgcttcga taagttcatc tagtttttgt acatggatcg
      661 ccagacgatc cagttcctcg tgaatatctc cgcgttccaa caagatggct agctccgtca
      721 acaaccgttg ctcatcgact ttcgctccaa gaaattcctc cagctttttt tgatacctta
      781 tttgaaattc cttttcatag atttctacaa aactatcgag tttttttagt acttctttga
      841 attcttcagt attctttttc aacactaaag ctaaagcttg accttctttt tctcgactcg
      901 cctcaataga atcaagtgcg cttttcaatg tatctagagc taactgtgcc aattcttcca
      961 tgctctcttc cggtttttct tctaccgtta cgaagttttc gtccagcgcg aagcgttccg
     1021 ccatccgact aattgacact tgattttgac taccgtatcg ttgttgaatt ccgtctgtca
     1081 attgagtgat aagtgaatca atcaattccc agttgatgac gatctgtttt tcgtttttgc
     1141 caatataagc tagattcaca aatacttcga ttcgaccgcg gcttaactgc tgtttaataa
     1201 gctgacgaaa atcgttttca acaaagttca ggattttagg acttcgtatt tgaacatcta
     1261 gaaaacgctg gttgacactt tttatttcaa tatctaactg atacgctttt gtttcgcgga
     1321 tggctttgcc aaaaccagtc atacttttca ttcgacaggg tccttcctca ttacatattt
     1381 tctattgctt tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc tttccccatt
     1441 ttttcatggt ctggcgccca atctcgaaga tcgaattttg gcgggcgacc attccagctg
     1501 actaggttca gttctttacg ccaccccttg ttgttttctg acaatatagc gatttcttct
     1561 acgatttcat atgaaaattc ttgtgccatg gttgttcctc cttgagataa tataaatata
     1621 ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga tccttgcgtt
     1681 ttccttgtag cagataatca aaataaacag ttttcgtgcg ctcattttgt attttttgct
     1741 ggtattttcg ataccttcgc cattcttcag tacttaattg accaatttgt gccaataaat
     1801 catccggcat actttttata tcttgttggc agatcatttg aatcatcatg tctacttgat
     1861 agatttcatt gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc gccaatccgc
     1921 atgtctctgg tacgaccctg ttcttatata aattacgcag tttttgccaa aattttatgc
     1981 ttttgaaaaa agataattct aactgaattt cttttgttaa gtaagacaaa aatcctcgcc
     2041 agtatgttct tgcaggttta acagaatgaa atgtatacca gttcccatag taatagccta
     2101 atcgtttttt catttccaga tagcctaatt gtaaatttaa ttggttcctt tggctatcaa
     2161 aaagcagaaa gctgcctagt gtccacaatg tttgacattt ccaatggata aaaatgtctg
     2221 gcatacgaat ttttttcgct gggcctggcc cttgcacatc tacgacaaat gcctctgttg
     2281 ctcctttgtt aatcgcaata tcaataggta ttttgttgcg atacccaccg tctgcatatt
     2341 tattttttcc gatctttcga taagccatag cgggataaaa tgaagcagag gcgagtatcc
     2401 aatctggtat ttcttctgtt tttgtctgtt ggatatcagt cactacttcc gctagttctg
     2461 gcagtttagt agacaccgta tataaacgta ttttgggatt atgtttgagt aaggacaaat
     2521 ccaaattgtc tttgaccatc ttttccaatg gagcagaaga aaccccgcct tcaattagtg
     2581 ctgttttcgt catttggcgt ctttctcgat agaagcgttc acgaaggtct tcaactgcag
     2641 ccatttctgg taacgcaagc acttgtcttg tcgacagctt tttccataaa ttcacagctt
     2701 ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag gtacctgtga
     2761 taatctcaaa gttgatatca tgttccttca gcgcctgcca cacaccaatc tgataagcac
     2821 cgtgcgctcc tcctccacct aaaacaagtg ctgtatgata gaccagcttt ttatttaatt
     2881 gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa ccattcttct gatagaggag
     2941 attgaaataa aaaacaacag ttttctttaa taaaaaaacg agcgcaagct tccatatacc
     3001 gaaaaaattt tttccattca aaagtttcac cttcaatcaa cagattatta aaaataacat
     3061 ctcctctact tttagcaata gtaaaataga cggtatattt tttcgatact gctttaaaag
     3121 cacattgctt ttttgcagaa cgccaaaaag cgtctctact ttcttgatga ctttgaaaaa
     3181 atggaagggg ttgttttgct tgctggatag gcgaatacag cgacattttc tgtgaaaagt
     3241 aaactttttt tatctccatc gcgctctcct ttttcttcaa gtataccagt acgtcataaa
     3301 aaggtcatga gtctcgtatt cgactttgta gattccataa gaaaacaatt cataaaacct
     3361 cctttaaata aaaaaataca aaaatcacaa aaattaattg aaaatgagag tgttttcaat
     3421 gaaaacgtga ttttgtaatg gaattttaaa ataaaagaaa caagcttttt taatgcaaat
     3481 gttgtaaaat aaaagagatt aagaggaaat aagaggagga acatgatgac tgagtcagtt
     3541 tatgtacata ttgataccac aagtaatgct gttttaacaa aagggctgac tgctactgac
     3601 tttgcaaaca gtatcgtgca ttttcctcaa aacttgctct tgcttgatcc atctgcttct
     3661 gctggagaat atgaatccca tacagggctg aaagtaatcc gtggtacaga aaatattcag
     3721 cgtttctttt cctcttctcg taacaggcgt ggattcgatg aattgaagtg gatcgacttt
     3781 actgatttaa cgatgctgaa agaattgaca cctttagaaa tttcagaatt attatatttt
     3841 ggtcatatga aaacacatct tcattcgccg tttttttata aactacagaa taattttgta
     3901 tacttcgatc ttaatgatca gctgaatcgg atttattatc gctatttaga tgaattttat
     3961 aggatttttg ctagtaaatt aagttcgatc ttgtcagata agatcaatgt aaaaaaatct
     4021 tttttcaaaa aagaaacacc tgttgaaaaa atcagtgtgg aattattgaa agaaatgcgt
     4081 aatttgatgc aggaagggat cattttttct tttgatcaag ttggtttgat cgatggtaaa
     4141 tatcgtatcc caatctatgt gattgaagat tatatttgga aattaaaagg cacccggtat
     4201 cgagaagagg aaatcatcgc tactttaatc tactctgtca ccgatcgaca ctggcaattg
     4261 gtagaagatg ccgatctttc ttatctgcca ttgaagtaga tctatttctt atcaaaaaat
     4321 aaaaaggaaa caagaaacta ggacatgatt ctgtctcaag tttcttgctt cttttttatt
     4381 tacagctcct gtcgtttatc tggcacaaaa atcgaaggag tcgtttgttg gatccctaat
     4441 aaaacgatga tcgttacaat agctgtactc aacccgctgg caccattcat tacgaaagaa
     4501 aagagccaag gattcatccc ccatagtgca tacgctcccc agaaaaccac tcctgcaata
     4561 aaatgccaaa aatatctgga aagtgcgcca atcaatgcac caaacacgat gctttttcta
     4621 atttgtttcg tattatcgtc tacatagcct ttttggacat ttgaagccat gagccctgct
     4681 gcgcctgcaa aagtataggc aatcgggtac tcaatcaaca cttgaacgac acttaaataa
     4741 taaacttgtc ccaacggaaa atgtaggatg ccccaaatga aacctgccag catccctgcc
     4801 tttgtccctc ttcttaacgc aaaaagagtc aatggaatct gccctaatga aatagaaaaa
     4861 ctgctgccga tctggatcgg aatcaacgac aacaccatcg ctaacgctgc aacaatcgtt
     4921 ccttctaccc aaactctatt ttttcccata aaaaaacttc ctcctttgaa taaaaaagtc
     4981 acaaaggagg aagcagcttt cgaaaatagt caaacagctg tttattcaca attcctacgc
     5041 tcgcataacc gatacaggta cgaagggttt agaaatagat tcaatctcag cccaattgga
     5101 ctcccctttg tgagtttatt tattatttat tttttgtttc aaacaatgga ctaactggtt
     5161 tgttttcatg gatacgtttg attgcatctc ccattagtcc gccaacactt acttcatcga
     5221 ttttgtcgat tttacgatct tctggaagat agatcgagtc tgtaacaact agacgctcga
     5281 tagctgaatc ttctattctt tgtaaagcag ggccggataa tactggatgt gtacatgaag
     5341 catacacact agttgcacca gcttctttca aagcattggc agccaatgtg atcgtacctg
     5401 ctgtatcgat catatcatcg atcagtacac aagttttgcc tttgacttgt ccaatgatat
     5461 tcattacttc tgcaacattt gcttttggac ggcgtttgtc tatgatcgca atcggagatt
     5521 tcaaaaattc cgctaattta cgtgcccgtg tgacaccacc atggtctggt gaaacaacga
     5581 caacatcatc gcctttgatt cctttttcta agaaataatt ggcaataagt ggcgcaccca
     5641 tcaaatgatc gactggaata tcaaagaaac cttggatttg aactgcatga aggtccaaag
     5701 tcagcattct tgttgcacca gctttttgaa tcatgtttgc tactaatttc gctgtgattg
     5761 gttcccgtgc acgtgcttta cggtcttgac gcgcatagcc ataataaggc atgactacgt
     5821 tgattgtttt tgcacttgct cgtttcagtg cgtcaatcat gatcagcaac tccatcaagt
     5881 tatcattgac tgggctgctc gttgattgaa taacatagac atgcgatcca cgaatacttt
     5941 cttcaatgtt tacttgaatt tctccatcac taaattgagt aacagatgat tttcctaact
     6001 cgacgccgac tgctgctgca attttctctg ctaatgggcg attggaattt aacgcaaaaa
     6061 tttttaatct tgggtcaaag taatgttttg acatggggac ctccactttc tttttcacaa
     6121 ctctagaatt ctacctaata aatagtagtc ataattttta aataaatcaa gtgattttgc
     6181 aaaagtctta gtttagataa gggagttttt ttgcatatcc ttctttattg acttgtcttg
     6241 ctctcgcaat tgccagcgca tattctggaa tattgtctgt aattgttgac ccggcagcaa
     6301 tcgaactgtt tttagctacc tcgacaggtc cgatgatatt cgtgctagaa ccaataaagc
     6361 tgtggtcgcc gacagtcgta tgatgtttgt tctttccatc atagttgacg aagacaacac
     6421 cacatccgac attgatttct tctcccagcg tagcatcacc aacataagtc aagtgaccga
     6481 ctttagttcc tttgccgatt tgagcatttt tcacttccac aaagtttccg atatggacgt
     6541 tttcgccaat ttcagctttt ggtcgtaaat gtgcataagg tcccacatct gcatgtttct
     6601 tgacatggct gctttcaatg actgagtttt caatgacgac gtgatcctca atcctactgt
     6661 ctacgatttt tgaatgtgac ccgatgacac aatcagaacc aatgactgta tttccttgga
     6721 tttgtacacc tgcttcgatc aatgtgtctg gaccgatttc tacgcctgca tcgatgtatg
     6781 tcgttgctga atcgacaaag cttacgccat tgaccatatg catctggtta attcgctttc
     6841 tcatgatctc atttgcttta gctaacgcga tccgatcatt gactcccatt gattcttcaa
     6901 aatcatccgt ttgataagca gcaactgtat ggccttcttc ttttaagatt tcgatgatat
     6961 ctgttagata gtattcacct tgagcattgt ttgttccaac tttgcttaac gcatcgaaca
     7021 aagcttcgtt gtcaaaacag taagttcctg tattgatttc ttgtacaaga gcttcttctg
     7081 gtgttgcatc tttttgttcc acgatttttt ctacgatccc aatatggtca cggatgattc
     7141 gtccatatcc tgttgggttt tctgcttgtg ccgtcaagat cgttgcactt gcattttttc
     7201 cttggtgata ttcaaaaaga ttgttcagcg tttcagtagt caataatggt gtatcgccac
     7261 tgataactaa cgttgttcct ttttttcctt ccaagaaaga agcagcttgc aaaacagcat
     7321 gtcctgttcc caattgttct gcttgtaacg catatttact gcgttctcct agttgtgctt
     7381 taacttgttc tgctccgtgt ccaacgatcg taatcacttc atctggtttc gtttcactga
     7441 cccgattaat gatatgttct accataggtt taccagaaac gggatgtaaa actttatata
     7501 attttgactt catgcgggta cctttccctg ccgccaaaat aattgcataa cgtgcgtcca
     7561 actgcgtcac tcctaaatat agtttgctga tttcagttta tcccagtata cccatttttt
     7621 caacaaaaca agtgattttc ttttatccca gcgttttctg gataaaaaaa tagatagacc
     7681 ataacgggcc tatctatttg gtaaccggtg ctctcctgcc aactcctcgg tcacaagtca
     7741 cactactcat aaaacatgaa aagctgtttt ttgaaatcgt ttcttgtgac ttagagttaa
     7801 acggtaggct tacaacctct tcattaaacg tttttcaatc agctgacctt cggtattagc
     7861 tcaataaacg gcaaaatatg aggagcaatt tttccgttta ttgagctaat actcaggaca
     7921 ggacgctgat ttcacaacct ctagataaac ggtgttcaaa agccagtttc tcggtattaa
     7981 gccaaattta tgaaaaaatg tggaaagcca ttttcacaaa atttttctta ctactcgaaa
     8041 ctaagcagct ttttcacaac ctcttattct gaaaaataat ttcctggcac aaccgtaata
     8101 tttttcgttt gagtatctac atctttgaca taaagcagtg acgtataatc atcgatggcg
     8161 cgatgaccgt tgaattttga ttcggcaaat acagtgatgc caacaagttc tgattcgaat
     8221 tcttcaatca agctcttcat tccgttgact gttccgccgc ctttcatgaa atcatccact
     8281 acaaggacac gtgaaccacg tttcaaactt ctcttagaca gttccatctt ttcaattctt
     8341 tcagaagatc cagacacata gttgacactt actgttgatc cttctgttat ttttgagtcc
     8401 cggcgtacaa taacgaatgg cgcattcaga taataggaca cagcttgggc aataggtacg
     8461 ccttttgtgg ctacagtcat tacagcatcg attttttcac caaggtattt agaagcaatg
     8521 attcttccaa cttgacgcag cagttcaggt tctcctaaca aatcagagag ataaacatat
     8581 cctcctggaa gcagacggtc ttgttctgat agacgttctg ctagagattc aatatatttt
     8641 ttcgcctctt catatgaaat ttcagggatg aacaatacac cacctgcagc acccgggatt
     8701 gtttccaagg ttccataccc tcgttcttta aatgttttct tgatgattcc caaatcttca
     8761 ctgatagaag atttagcaga ttcataacgt tcggcaaagc ttgttaagga aatcaattca
     8821 tgcgggtgat tcaataaata ctgtgtcatg tcaactagac gttcactgcg acgtactttc
     8881 acctattcca actcctttta agaaatttta tcgttttaca ttatataagt ttttcttcaa
     8941 aaattcgagc attttatgaa aaaataagaa aatagttcgg tatttattaa aataaaaaga
     9001 agcctataaa aaatttttcg tttttataag gcttcttttc tttataattt agttattttt
     9061 tcttctgaag gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa
     9121 gactaatgtg attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga
     9181 cagcatccct agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc
     9241 taatcgcata ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc
     9301 aatcgggatc atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa
     9361 atgaacgggt agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg
     9421 ccgtttgaat aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac
     9481 ttgctcccat gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga
     9541 attccctccg ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat
     9601 ggcaatggag atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc
     9661 tgctaataca acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa
     9721 cgctacccct gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat
     9781 cactaaaaac acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc
     9841 tcttctcatg aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg
     9901 atctgtctgt ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat
     9961 ttcccatgga catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca
    10021 tccatacctg ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc
    10081 gctaaactga ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata
    10141 tcccacatcc ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga
    10201 cgcttgaacc agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta
    10261 ggaaaacctg cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt
    10321 ccttcttgat ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac
    10381 gatgctttca ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca
    10441 cccgcatcta catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc
    10501 aaatcagata tttcgatata acgcacctta caacctccat tctaaaactt aattgatact
    10561 ttcttttaaa gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat
    10621 ttgttcatta gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt
    10681 cgacaatgtc tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt
    10741 gtttttcttc acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg
    10801 tgaaacgccc gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc
    10861 agcatgctga gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg
    10921 atccagtgct tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt
    10981 atctggatat ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac
    11041 cggatcgagc caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc
    11101 ttcatgttcg tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat
    11161 caaggtctgt ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga
    11221 actattatac acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc
    11281 gaaatcatgc ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac
    11341 gatctctttt gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt
    11401 tttgtctgct tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac
    11461 cgtagctgtc aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt
    11521 ttacgattta ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc
    11581 atcaatttct gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg
    11641 ctcatatcta gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca
    11701 gtttttcatc acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt
    11761 cctcacaaaa accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca
    11821 aggcaaaaac ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca
    11881 tacgctcttt gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt
    11941 ttcccatttt tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt
    12001 ggatgtcttg atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga
    12061 cactcattct tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga
    12121 tttcttcccc tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg
    12181 taccgacttc caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt
    12241 ggttgatccc tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta
    12301 ctggaatatt cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta
    12361 gcaataaagc agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg
    12421 tttctacaat gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta
    12481 cgctcgacat caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca
    12541 gtcctaaatt tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa
    12601 aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct
    12661 agtggttgat tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa
    12721 caagttctag tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc
    12781 ctttttcttt tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt
    12841 tcctataagc aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag
    12901 cagacaggaa ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt
    12961 gaaagaaaga aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt
    13021 ccgagtagcc cattttctcg tatacaataa acagattggc taacagatag tcagctaatt
    13081 cctcagattc tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg
    13141 gctgagcggt gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag
    13201 ataatacata tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa
    13261 gccatttttg tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc
    13321 aagtaaaatg gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag
    13381 acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac
    13441 ccaattcatg aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc
    13501 ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc
    13561 caactggatc tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt
    13621 gatcttggtc gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc
    13681 ttgtagctgt gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac
    13741 tgccaagctt cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg
    13801 agatgcccaa accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat
    13861 gatttcctgt tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa
    13921 cgataaacaa aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga
    13981 attttgttcg ataaaattct tttctggata accacacagc taacagaatc aagacatata
    14041 ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta
    14101 aagcaatcgt aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga
    14161 gtaataaaaa gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca
    14221 ataatacttg aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca
    14281 tcatgatccc cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa
    14341 acagtcgcgg aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca
    14401 atagaagtcc cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa
    14461 ctactgctac atcttgccga acaggcaatt gactcattcc taagatcatc aaaacgtcaa
    14521 aagtccccat tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca
    14581 taggatagat cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata
    14641 ccgcaagggc tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg
    14701 gataaaactc gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg
    14761 ctaaaaaact accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa
    14821 taaaaaagac atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata
    14881 gtgcgacttt tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac
    14941 tagcccgcag acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg
    15001 ttacccacgc agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta
    15061 agactctgat cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca
    15121 gaatcatgag caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc
    15181 aactcatgcc attagcaata tttgcgactt gatttgccac aaagactaac acggagccga
    15241 aaaaaatcag ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt
    15301 tatttttcac attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc
    15361 ttatttattt taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa
    15421 agatatccta atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat
    15481 atggcacaag ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg
    15541 ttcgtttcca gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat
    15601 gcatgcaaaa gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa
    15661 ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc
    15721 atttctattg cttcaggaaa atcattaaca gatttagaaa cagcgcttga agatcctcag
    15781 gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg
    15841 atttgcaaaa atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa
    15901 gcaatcggca gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct
    15961 ggcagctcac ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg
    16021 aatggtttgt ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt
    16081 caaaaattcc tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct
    16141 ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc
    16201 atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga
    16261 tagcaatgtt ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt
    16321 cttttgtatt ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac
    16381 tttgatgtgt ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa
    16441 acgaacagcg tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc
    16501 agcttgaact gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact
    16561 tcttaaacga cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga
    16621 gagcgcatct gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg
    16681 atgagaagcg atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc
    16741 accgatctca acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag
    16801 caacccggca cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc
    16861 taattttgca acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg
    16921 cagacgtccg atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc
    16981 tgcctcttcc ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat
    17041 ttcttcgata cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg
    17101 tgcgatttct cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc
    17161 gatgattaaa tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc
    17221 aatgatacga cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga
    17281 aacttgatct gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc
    17341 tgcttcttct ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag
    17401 ctcttcttca gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat
    17461 tttttctagt tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc
    17521 aattaattgc tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt
    17581 ttctaacgag tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg
    17641 agattttaat tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg
    17701 attttcttcc ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc
    17761 actatcgatg attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga
    17821 ctttgcgacc ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat
    17881 gttgaatacc ataaaatcca cctccatact atctttttca tttttatcat ctatacagct
    17941 tctatgataa attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa
    18001 catgcacaac tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa
    18061 acggctttct acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat
    18121 aggtaaacct ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata
    18181 tttttatttt atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa
    18241 aaaacggcag gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat
    18301 ttttattctt ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact
    18361 tcttcaccaa taccataagc tgctctaact agagcagaaa cttctgccat catttcagga
    18421 tgattagcca tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa
    18481 gaataccaag caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct
    18541 ccttcttgtg agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt
    18601 gctactttgt tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt
    18661 ttcaattgtt ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt
    18721 cctccaggag tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg
    18781 atgaaaatag cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga
    18841 gacatcaaac gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct
    18901 cgtggaacta aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact
    18961 aaagcatcag cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca
    19021 tcgatattca cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg
    19081 aaagcggccg ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt
    19141 ttacctgaac tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca
    19201 cctaaagcga catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt
    19261 ttttcgccca atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca
    19321 gcatctaagg ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat
    19381 cagagcaaca tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac
    19441 cgaacaaata ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct
    19501 tgcataaccg cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa
    19561 accacgccgt ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac
    19621 gtgtccggtc cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt
    19681 gcttgaatgg ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc
    19741 tccggatcaa tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct
    19801 ggaaatactt cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc
    19861 aaactttccg ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt
    19921 gctagcgaat tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt
    19981 tcttctaatg ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt
    20041 cgtaatgtca cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca
    20101 atcagatctt ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact
    20161 ttagaaatta gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc
    20221 acaaacattg gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct
    20281 gtttgataaa aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg
    20341 ataatctggg actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat
    20401 gccaataatt ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca
    20461 gttgcttctt ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt
    20521 tcacttcttg tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca
    20581 actgtttgat aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca
    20641 ttcgtattca cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc
    20701 attacttccc gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag
    20761 agggcaagga gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc
    20821 tcctgccaaa acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg
    20881 aaattatccc ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata
    20941 cttacattga tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga
    21001 tagtaaagat cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga
    21061 atgggatatt attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt
    21121 ttcccggcca agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg
    21181 tgacggctaa ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt
    21241 caaccaacat gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact
    21301 tgccaaaatt agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga
    21361 tactagctaa agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc
    21421 ctacgttaaa ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca
    21481 tacaaattct aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc
    21541 ctattctacg tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt
    21601 tattcaaagg agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga
    21661 cacagatttg tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat
    21721 ttatacgatc attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt
    21781 tcccctggat taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca
    21841 ccaatcgtga tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt
    21901 gctgccagtg tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga
    21961 ttgacagcag taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg
    22021 gcactgccag aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt
    22081 gttgattcta ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc
    22141 tcgactgatc cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga
    22201 cgatcttgcc aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat
    22261 aaaatgacag gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct
    22321 tttctagaag tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg
    22381 cttttcccat caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat
    22441 tgccgaataa atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg
    22501 attgcttcca aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt
    22561 tttttattca ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca
    22621 tcttctccag tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt
    22681 tgggtgctgt gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct
    22741 gccaactcct cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact
    22801 tgttccttgt gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca
    22861 atcagctgtt cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt
    22921 atgtttctct aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt
    22981 caaaagcttg catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt
    23041 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg
    23101 tgttccagaa gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat
    23161 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta
    23221 cttcgtttga ttttatttta atataagttg attaaaagag agcatgattt gttttatttt
    23281 ctcactaatt tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc
    23341 tactacaagt ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt
    23401 ctcatgtaaa actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg
    23461 tctttcattt ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat
    23521 aaactttgcg taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt
    23581 ccaagcattt tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg
    23641 aatccaagaa tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg
    23701 ctgaagtccg caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg
    23761 ataattcctt gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg
    23821 aacaacagat tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg
    23881 tctaatcctt taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt
    23941 tgtttgatga tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg
    24001 aaattttttg cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta
    24061 ccaactacaa ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag
    24121 tcttgagctg tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg
    24181 tgtgtaggat acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca
    24241 tacatttgga tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag
    24301 taaggtgctt gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta
    24361 gaaaacagat agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc
    24421 ccaaataatt gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg
    24481 gcaattccat ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg
    24541 atcgaaccat aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac
    24601 aaatacacgg tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca
    24661 tattctgttt tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat
    24721 ttgctcagct acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc
    24781 ttcatcagat aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc
    24841 ttgcggagag tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag
    24901 ttccaactct gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag
    24961 tacttgattt cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt
    25021 atccacgcta ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag
    25081 tttagagtga ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg
    25141 ttcatcgtaa tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc
    25201 acgtacttgt cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata
    25261 aactgtttcc cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc
    25321 aacatcgccg acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga
    25381 cgctagcgaa ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt
    25441 ttgttccggg ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt
    25501 atcttccttc aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa
    25561 ctgatcaaac tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac
    25621 cgcttgagaa aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc
    25681 gtttagccaa tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag
    25741 ctctgcaagt tgcgcactta actttgtctg atccggataa ttcaaactat ttgtttccaa
    25801 catgctgctg agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg
    25861 gataaaaatc cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc
    25921 tgccaattga tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt
    25981 ttaatgggtc aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca
    26041 attcgccgtt ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca
    26101 aaagaaacag acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta
    26161 aagacaaata aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc
    26221 gtggagatgt cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg
    26281 taaaccaagt ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca
    26341 caggtacttc tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg
    26401 tcacatttgc gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg
    26461 tcttattctt agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc
    26521 aagtggaagt ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc
    26581 ttgccaaaca agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata
    26641 cttctaaata ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt
    26701 tttagattct taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc
    26761 caaatacaca tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc
    26821 ttgtgcgccg atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc
    26881 ttgaacaatc tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc
    26941 aaaatggata ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt
    27001 atcttgaaaa aacgtatgcc aagcttgtcc atcaatgtca tcaacttctt gataaggaca
    27061 ctgttgttcc acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt
    27121 tgacaattct tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt
    27181 attcttagca taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg
    27241 tttgcttttt aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct
    27301 gaatagctgt aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat
    27361 actgaaggat aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc
    27421 tgagcaacca acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct
    27481 aaagttgttg gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt
    27541 caagtttacc ataaaaaaaa aagaaatgca ataaaaataa ataagaagct cattaagatt
    27601 tttctaaatt attcctcatt ataaaatttc aagtgttttt ttattttgag ttttactctc
    27661 ccgtaagcgc tcattacttg cttgtgatcc attgctaaac attcagccat gtctacaaaa
    27721 tcaacgcctt gcatataata atgaaaaatt ttagcttcta tttttgaaaa ctggatttcg
    27781 caattttcga ttgcttcttt taataaaaga tgctgaatcg ctaaaggttc ttgcaatgtg
    27841 atctctgcta aaaagtctgg tccttctgtc tctatttttt ggtcgattga gacttcatct
    27901 ttttgatcac gacgcttcag cgcgttctgc ttcctcaaca gagaatagat ttgattgctt
    27961 ataatgcttt tataataact tccaaagcta acacctttgc ttttttcgta agttctcaat
    28021 gcctgatata aagcgatcct tgcttcttgt tcccaatcct cagaaacata atttcttaaa
    28081 taataggtgt ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag ggcagcaaat
    28141 gcttcttcgt caccattacg tgcagcgcgc aataactcct cagacataaa ataattcctc
    28201 cataaattcg tttatggagg aatcttatca tcaatgattc atcgaactga ttagaacgat
    28261 atgttattta ttttttctca ttaaatcgtc caatttttgg gacaattttt ttaactgctc
    28321 ttcattccat ggagaattac gtcggaaatc aataaaatgc atatctttat tttcttgggc
    28381 tattgttttt tccgtttttt ttatcgtctt atataattca taagcagaag ttcgtaatgc
    28441 tccttgggaa aagatcatcc actgttctgc taaatcgctt gtcgccactg tcacttgtgt
    28501 caaacggtca ttcagctgac cagcgattct ctcgatataa ctgtcagccg tttcgtcttc
    28561 tttcgtaaaa acaacatcca actggtattt cttataattt tgttggatgc ccggaactag
    28621 ttgggcatcg aagacaacga tgacttccat tccttcatat ttcgcataat ttgataaacg
    28681 atgtaaaaga gcttctcttg catccgccat tttgtcctgc tttttaagct ggacaagttc
    28741 cggccacgaa ccaatcatgt tgtagccgtc tacaatcaac agctgttttt tcatggtcta
    28801 ctccccctga cgttgggaaa aagcctgata cataagcaaa ccagcagcaa cactggcatt
    28861 taagctctgg acgtgcccgg tcatcgggat cgtcagcaat tcatccattt cttttttcaa
    28921 tcctggactc attcctttgc cttcattacc aatgactaaa gcaattgatc ctttggcatt
    28981 ccatttttgg aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc ctgtttcttt
    29041 gagctgttgc acagcttgta ccaaattcgt cacgcgtgca acagggacat gttcgactgc
    29101 cccagtggaa gtctttgtta cgataggtgt gattccaact gctcggtgtt ttggtatgat
    29161 cacaccatcg acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat tgtgtggatc
    29221 ttcgatgcta tccaaaatca aaaagaaggg gtcttctttt ttctcttttg ttcgttcaat
    29281 cagttggtca agggataaat attcataagg tgtaatcgca agaacgactc cttgatgcac
    29341 gccgtgatcg ctcaaagttt ctaatttttg tttaggaacc catttgactg gcacagcttg
    29401 ttcacgtgcg atttctttca gttcttctac tttttctcct cgtgaatctt cttgaagaaa
    29461 gagtttattc cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc caaagacgaa
    29521 attatcttct aatgcttctt cattttgatc agaaactgac tgatttcgtc cagtttgctt
    29581 tttatttgaa tatctatttt gttttttgtc ttcaaatcca cgtttcgatt gatgtttgtt
    29641 tgttctttct ttacccattt ttttcaccaa ctttctgaat acaccagcgg atcaattctt
    29701 ccatccgctc ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg aaccctgttg
    29761 cgacccgata cgtcgtaaca tcagcatttt ttgcgctcgt atggctttta gcatttcttc
    29821 ctctgcgata ataaagttct tcttcttctg tcaaaagatg ttcttccagc atttgctgaa
    29881 tcaaaaaggc ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc agcttattgg
    29941 gttttgtttc tccttgatca atcaggtggt cacgaacata gatttcgtaa atcgcatctc
    30001 caacataagc caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt ctcttctcca
    30061 tcgggttcct tgcggtgtat cttctaataa gatccctttt tctttcaaca aatcacgaat
    30121 ttcgtcgctt cggacaaaat cacgattgct tcttgcttga tttcgttctt cgatcaattg
    30181 ttcaatctct tcatctaata actcttctgc tgtaaataaa ataccgaaga tcgaaagcca
    30241 ttgcgagaat aaagcttctc cttgtgccaa gacagcggca gaaactttcg gctggtctag
    30301 ataagtgttc agccacttag caagctcata gaccactgtg atcccatttg ctgcattaaa
    30361 atcatcgtcc atttcttcga tgaatcgctg ttctaaattt tctaacaaag cgattttatc
    30421 cgcatcatct gccaaattct ctgaggcagt ttcttggcgg aatttcaaat tgtcaaacgt
    30481 attcttcagt cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac tgtagcggat
    30541 cggacgacgg tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat caacgttttt
    30601 gatcatttca tgtacagtga tgaaattccc tagagattta ctcatttttt catcgtcttc
    30661 gccaatcgtt acatagccat tgtgcatcca gtaattagcg aattttttcc ctgttttcgc
    30721 ttcactttgt gcgatttcat tttcatgatg aggaaattct aaatcttgcc cgccaccatg
    30781 gatatcgatc gtttctccta aatgttttgt tgccataacg gaacattcaa tatgccaacc
    30841 gggacgtcct ttgccccatg gtgaatccca agaaatctcg ccaggttttg cttgtttcca
    30901 taaagcgaaa tctaatgggt cttctttttg ctgctgttct tcccctgtac gctgacttgc
    30961 tccgacttcc agttcatcga tggattggtc acttaatttc ccataatttt caaatttacg
    31021 ggtacggtaa tacacatcac ctgaagattc ataagcatag cctttttcaa ccaacacttg
    31081 aataaatgct aaaatatctg gcatatgatc catgactctt ggatgcagtg tagcaggctc
    31141 gacattcaac gctttcgtat cttcttcaaa tgctcggatg aaacgatcag caacttctgg
    31201 tgctgtaata cctaattcgt ttgctgtacg gatgatttta tcgtctacat ccgtgaaatt
    31261 cgatacgaaa tcgactttat agcctcgata ttcaaaatag cgtcgaattg tatcgaaagc
    31321 aatggtgcta cgagcatttc cgatatggat ataattatac acagtcggtc cgcagacata
    31381 cataccgaca tgtccctttt gtatagggat gaattcttct ttttttctgg tcaatgtatt
    31441 gtagattttt atcattctga tctcctcact ttttctcctt tgattcgaac gacttttgct
    31501 ggtactccta ccgctgtagc gtcgtctgga acatctttca acacaacggc acctgcaccg
    31561 attttggcgt tttttccgat cgttaccggt cctaatatct gcgcattcgc agagagcatg
    31621 gctccttgtt taacagttgg gtgtctttta cccgtttctt ttcctgtgcc gcctaatgtt
    31681 acgccatgga ataaaatcac atcgtcctcg atttctgcgg tttcgccaat gacgattccc
    31741 attccatggt cgatgaacac gccagttcca atcgttgctc ctggatggat ctcaacacca
    31801 gttaggaaac gccagaattg agcattgatc ttcgccaata aaaagagccg gtgctgatat
    31861 aaaaaatgag agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt caaaacgatc
    31921 tcagctgtcg aacgtgcagc cggatcgttt ctctttgctg catcaatcgc tcgggtaaac
    31981 caactcatga ctttccactc ctttcgtaag aattttatgt aggaaatcat cttcttataa
    32041 agaaaagaag cgccttttaa ataagtttcc ttatcaaaag acgctttccg cgtggttcca
    32101 cttttcttca taatcaatga ttatctctga cagctaacgc ctgttatacg ttcttggcta
    32161 ctttgtttcc tataaaacag tttttcctgt tttctgtgtt tcgccaagac cactcccaga
    32221 ggcatttcgg caaccattca ttgatacctt gcaccacccg gtatctctct tgtaatgatc
    32281 agctgcttac ttttttctgt tcatcgtgtt tagttcagta cttgatttaa atgtgctaat
    32341 gatttttcac gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg catttgtcct
    32401 gatacagcta cacggattgg catgaaaaga ttttttcctt ttacgccagt ttctttttga
    32461 acagctttga tggcagcttt gacagttgga gcatctacta cttccatttg ttctagctgt
    32521 gctttgaatg cgtggagaac agtaggaact gtttcaccag caagtacttc ttttgctgct
    32581 tcattcaata caggatgttc attgaaaaat agcgtagaca gatcaacgat ttctgcagca
    32641 tagctcattt gaggttgata caggctaacg atcttcttca cccattcgat tgtcttttca
    32701 tctgggtttt ctgctacacg tccatcagcg attagataag gcagacacat gtcagtaaat
    32761 gcatctagat ccattgcttt gatgtaatgg ttgtttaccc attgcagttt tttcgcatcg
    32821 aaagctgcgg gtgatttact taggcgtttt ggatcgaaca ttttgatcaa ttcttggtgt
    32881 tcgaagattt cgtcttcgcc cacaggtgac cagcccaata atgcaataaa gttgaacatt
    32941 gcatctggta gatagcctaa ttcgcgatat tgttcgataa attgcaagat tgattcgtca
    33001 cgtttgctta gttttttacc tgtttcactg ttgatgatca atgtcatatg tccgaaggtt
    33061 ggtggtgtcc agccaaatgc ttcatagatc atcagttgtt ttggtgtatt ggcaatatgg
    33121 tcatctccac gtaaaacgtg agtgattttc atcaaatgat catcgaccgc aacagcaaaa
    33181 ttataagttg gcataccatc gcgtttttgt atgacaaagt cgccaccgat attatcggat
    33241 tcgaacgaaa tagcgccttt caccatatct gtaaatgcgt attctgtatt gcgaggcaca
    33301 cggaaacgta caacagattc tagaccttgt gcttcttttt ctgcttgttc ttcaggtgtc
    33361 aagttcgcac atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg tgcttcccgt
    33421 tctgcttcta attcttcttc tgtgcaatag catttgtatg ctcgattgct agcaagcagc
    33481 tgatcaatca gcggttgata gatttcttta cgttcagatt gacggtaagg gccgtattct
    33541 ccaggatttt caggagattc atcccaattc attcccaacc aagcaaggtt ttccaactgg
    33601 cttttttcgc catcttcgat attacgtttt tggtcagtat cctcaatacg aataataaag
    33661 tctccatcat tgtggcgggc aaacaaataa ttgaataatg cagttcttgc atttccaata
    33721 tgcaggtgcc cagttggact tggtgcatag cgtacgcgta ctttcgtcat tttcttcctc
    33781 ttctttcaaa ctagactttg actaacagca aaaattccgt cagttacggc ttctcaaata
    33841 tcatttattt aaagccactc agcacaaatt ttaccttttc taaggtaaat agtaaagcca
    33901 actggttgaa tttccttacc agttggctga atttcttttt tattttgatt gtttagtctt
    33961 tttctctgtc tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt tagcaaagat
    34021 catgcgtcca gcagctgttt gaagggcact tgttacaacg acttcgatac gttcattcat
    34081 gtaatgctgt ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg ctactccttg
    34141 ttggcgttct gtcccggctt ttactactag aacattcatc gtttcaccag ggatgacgac
    34201 tggttttacg gcatttgcca acgcattgat attaagaaca ggtacatttt ggaattcaga
    34261 gactttattc aagttatagt cattggttac aatgacacca tctaaaagct tagccaattt
    34321 gatcaatttg ctgtctactt cactgatatc ttcaaagtct ccatcgtaca tttcgacaga
    34381 tataccctct tctttttgca aggcatttag gatatctaat ccgcgacgac cacgcacacg
    34441 tttcaaacta tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa aattagggat
    34501 catcaaggtt ccttctaaga atccagtctt tgtaatatca taaatccgac cgtcaatgat
    34561 cacgcttgta tccaagattt tatatttatg gaaattttct cctgattttc gttctaacag
    34621 ttgactctca acttgactag ctgtttcttg ctcgattttt ttgcttcgtg aaccaaaaac
    34681 tttcttccat tcttcgattc gtgtcgttcc cattctcaat cccagatagc ctaagatgat
    34741 catcagtaaa atcggcaata cactattgac gaatggaatt tccatattgt aaagaggggt
    34801 cgagatcaca acacctaaag tcaatccgat gatcgcaccg atcgcaccga agagaagata
    34861 agtcaagctg acctcactta gtttttgttc tacttgtttg ataatagctg agatatgttt
    34921 ggccaacagc aaagataata aaaagaaaat aagtgcgcct aacaggctgt tggtaaatgt
    34981 attattcagc catccgtttg actgttgacc gattgcctgc caagctgagg gtaaaaatga
    35041 aatacccaag cttgcgccga caatgatcat cagcaaagta atgacacgtt tttgcatcgt
    35101 ttttcctccg tttcgacaat catttattag ttagcggaac acacgcttca acgtttcagc
    35161 caaagttgct actccaacta tctcgattcc ttttggcgct tcccagttac ctaagttgtt
    35221 tttaggtagg tatacttttg tgaagccgag tttttggact tctttgactc gttgttcaat
    35281 atgactgaca cgtctgattt ctccagtcag tccaatttca ccgatgaaac attccgttgg
    35341 ctgtgttcct ttttctttat agcttgaagc aatactgaca gcgatagcta aatcaatcgc
    35401 tggttcattt aattttaccc cacctgcagc ttttaagtaa gcatcttgat tctgaagaag
    35461 caacccagct cttttttcca gcactgccat gatcagagat acccgattga aatcaagacc
    35521 tgttgttgtt cgtttggcat ttccgaacat agtaggtgtg actaatgctt ggatctctac
    35581 caaaattgga cgtgtccctt ccattgccac aacgatagca gagccagttg caccgtctag
    35641 gcgttcttct aagaaaatct gtgaaggatt agcgacttct tccaatccat gctcatgcat
    35701 ttcaaaaatc ccaatctcat tcgttgagcc aaatcggttt tttactgctc gcaaaatccg
    35761 aaaactatga tgttgttcac cttcaaaata taacaccgta tccaccatat gttctaacat
    35821 tcttgggccg gcgatcgagc cttctttggt aacatgaccg acgataaaaa tggctatccc
    35881 atttgtttta gcgattttga gtagttctgc agtggtttct cttacttggc tgacacttcc
    35941 tgccacactt gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga taacataatc
    36001 aggggagata tgttcgatgg cacgactgat ttcgttcata tctgtttcag cgtatagata
    36061 aaattctgtg ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct ctgcgctttc
    36121 ttcgccggat acatataaga cttttccgcc tatggctgct aattgctgag aaacttgtaa
    36181 cagcaaagtg gatttcccga tacctggatc gccaccaatc aagaccatag accctggcac
    36241 cacacctccg cctaacacac ggttcagttc ttctaatttt gttttgatcc gaggttcttt
    36301 tttagggacg acgtctgcga tttttgttgg ttttgctttt tctcctgtca aacttgtccg
    36361 agttctgcgg tccgttgtat cttgttcgat ttcttcgacc atcgtattcc attttccgca
    36421 atttgggcag cgtcccaaga acttaggcga cacatacccg caattttggc aaacaaattg
    36481 tacttttgat ttttttgcca ttgtaccgcc tccttttatc ctaatcatga gacattaaat
    36541 caagcttaag tatctttaac gttttattta ctggaagaac caaatccgcc ttgacgttga
    36601 gcagtcgttt gatcttgatc tgcttttaaa aacggcaaaa agatcccttg gccgatacgc
    36661 tcgccttttt tgatcactac atccttgaaa ccaaagttgg tgaattggaa catgatatgg
    36721 ccttcatttg cctcattatt gtaataatca ctgtcaatca cacctactcc gtttgtcaac
    36781 actaaaaacc gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa ttcatcttct
    36841 cccatgtaag ctttgattcc agtaggcacg agggttggtt tcaattgttt ttcattttct
    36901 gatacatctt ttttcaatcc atctgcgact gtttccaacc cctttttcca gcctgctttc
    36961 cagatacttg gaatcacgac ctcttctgct gcttcaaaat catagccagc agcatgatgt
    37021 gtagcgcgct gcggtagatt gatattttga tctttatatt tagaaataac ttcaaatcct
    37081 ctttttctca ccggttttcc tccctaaata aactactcct attctaacat atccgaggct
    37141 gtaaaagact ttctttacaa attcttcaag aaattctgct atcttaaagt aaaccattaa
    37201 ttcgttcttt ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta catgacttta
    37261 ctcgtcaaaa caagtagaat agaacgaaat taatgagtgg atatttgatt gaggtgtcac
    37321 atgcgtaaag aaattaaaaa tgcaaaacga attattgtca aagtaggaac aagtacattg
    37381 atttatccca atggaaatat caatcttgcg gcaatcgatc agttagcttt tgtcctttct
    37441 gatcttagaa atcggggaaa ggaagtgatc ttagtctcat caggagctgt aggcgttggt
    37501 atgcataaat tacatttgtc agaacgtccg actttgattc ctgaacagca agctgcggcg
    37561 gctgttggtc aagccgaact gatgaatatc tataatcaaa gattcagtgt atataatcaa
    37621 cagacggcac agatcctcgt gacaagagac gtggtagatt atcctgaaag tcgtaaaaat
    37681 gtgaggaata cattggaaca gcttttgatt atggacacga tccctatcgt gaacgaaaac
    37741 gatactgtag cagtggatga attagatcat ctgacaaaat ttggcgataa tgatcagctg
    37801 tcagccatca tggcaaaact tgtcgcggca gaccttttga tcgtcctttc tgatatcgac
    37861 gggttttatt cagataatcc gactacaaat cccgaggctc agatgtatcg ctatatcgat
    37921 aaaatcgatg aaaagattct ggcacaagca ggtggtgctg gtagcacatt tggaacaggc
    37981 ggtatgcaga gtaaattaaa agccgcttct aggatatttg aagcaaacag cgcaatgatt
    38041 ttagcaaatg gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa agaagtaggt
    38101 actttattta aggaggactt gaaatgactg acttgatgca attaggacaa caggcaaaag
    38161 atagcgcgca acaactagca cttatgccta caaaccgcaa aaatgagcta cttgttcaaa
    38221 tggcacaaac catcaaaaag aatcaacaag cgatcattga agcaaatcat aaagacttag
    38281 aaaaagcagt cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag ctgacacctg
    38341 agcgaatcaa tgccatggct acagagatcg aaaaaattgc ttcgttagac gatcctattg
    38401 gaaaagtaga tgagatgtgg acgaacaccg acggattgag aatcggcaaa aagcgcgtgc
    38461 cactaggcgt gaccggcatc atttacgaat ctcgtccaaa tgtcacgaca gatgcagcta
    38521 gtctagcatt caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa gcattcttct
    38581 cgaatcaatt attagtccaa ttattgcagc aagtactggt cagtgctggc gaatctcctt
    38641 atgccatcca gtttgtcgat gatacttctc atgaaactgc aggacagttg atgcgattga
    38701 cagaatactt agatgtgctg attcctcgag gcggagcaaa attaatccaa cgagtcaaag
    38761 aacaggcaac ggtacctatc attgaaacag gtacaggaaa taatcacgta tatatcgata
    38821 aagaagcaca gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct tcccgtccat
    38881 ctgtctgtaa cgcggcagaa acattgctga tccattctga gatcgcacct tttttcttgc
    38941 cagctattga aaaagaactg gtagaacacg gggtctcttt acgtgcggat gctcgtgcgt
    39001 tagaatatct agagacggct gctttagcag aagacacaga ttgggatact gaatatctag
    39061 attatatcct tgctgtcaaa gtggtcgatt ctttggatga agcaattgca catatcaatc
    39121 ggcataatac taaacattca gaaacgatcg tgacagatag ttatgcggct agtcaacgtt
    39181 tcttaaatga agtggacgcg gcggctgtct atgtcaatgc ctccactcgt tttacagacg
    39241 gatcggtatt tggttttggt gcagagattg gtatctctac tcaaaagttg catgcccgtg
    39301 gtccaatggg gttaaatgaa ttaacttcca caaaatatat catttatggc gatggacaaa
    39361 tccgcgaata atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt tctgtaaagg
    39421 ttctatccaa ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt tttatttacc
    39481 ttatttctct gaatatcgct gcttttctgg gagtcggtat tttatccctt ttctttcaat
    39541 tcaaaaaacg aagcataggg agtcaacggg aaaaatggtc gcagtatttt gacaaaatcg
    39601 ggcaaaaagg gctggttaca cgcttgcaca ttagttacat ggttgcatta tgcttattag
    39661 cgacaatcaa ttactattct tttttcgatc attcaatcgc ttatacgatt acgctactga
    39721 ttgctgggat ttttcactta tcttataaat atcagctgaa taaaaaccac ttgaatcgga
    39781 ctttccgcta aaaaatatcc gtacgataag tagagtgcct tgaagatcgg caaaaaactg
    39841 ccggactttt tagaggctgt gacaaagatt ttgtcacagc ctctttttcc atataaacgg
    39901 cgttcgccta ccagctgcct ggtaaatctg tttcctcttc gttaagaagc gaaaatccgt
    39961 caaatgtttc gccatcataa taacgaagca gctcatccat ggacaagttc atcgtttttt
    40021 ctttttcttc ttccgctgat tcagccagta gctgttcccg atacacctga tacataccag
    40081 ctattttttg ctgcatcgct tttctagttt caccttccgc attgattatt ggcaattctt
    40141 tgatatagcc acgataaatc aaccgatcat ctgaaaattc aatgggtaat tcaacgagtg
    40201 tcaacccgac ttcctgaaaa tattcttcca gcatctatta tccccccatt ctttttctta
    40261 aatgaatttt agcttaccta ctgaaaattt tccagtttca ttattttgag aaaaaaaggg
    40321 aatgtgacaa aaatcgtgtc acatcccctt tttccgaata aatggtgttc ttctgccaac
    40381 tcctcaatca taagtcacaa tattcaacaa acatgagaaa ctgttttttg aaattgttcc
    40441 ttgtgattca gagttaaacg acagtctcac aacctcttgg taaacggcgt tcaaaagctt
    40501 gcatctgcgg taataagccc aaccaaacga aaaatatgag aagctatttt tgtttggctg
    40561 ttcttatgac ttgatgcagg acagcttttt cacaacctct gatttcttat tcttcttcat
    40621 ttgtagcaaa ataattacgg tgataaatga tacaacatac actgataaga acaatggcac
    40681 ctgcaaaata aaacgcatag ctttcaccaa tatgttcacc aatcacacct gcaataaatg
    40741 gtgctaaagc tccaccgaaa aagcggacaa aactatagct ggacgaagca acgtttcgtt
    40801 gcagacctgg tatttccata gcaatcgtcg tcaacagtgt attgataatt ccttggaaaa
    40861 atcctgctaa cacaatgctg atcggtacaa ggactggcat agaagttcca gctcctaata
    40921 acagcaaaca aataatgaat aagacaaatg ctgctaaaat tgtccgataa gtcgtaaact
    40981 tccgctcaag agccggtgca acgaaaatcg aagcaatagc cagaagcaca ccccagccaa
    41041 aaaatacaaa accgacttct aattcagaat agccaatcaa taaaaatggc gcatacgcaa
    41101 gtaaagtaaa gaatccgaaa ttatataaca atgcgattag tccaactgaa cgaagtttat
    41161 gattgcttaa cgctttgaca ccttcccaaa ggcctacttt tctctttggt ttctcagttt
    41221 caggtaaaag taccgctagg gctataaaac cgcaaaacat caaaaatgct accccaaaaa
    41281 atggataacg ccatgaacca ctgcccaaga ccccaccgac tagagggcca acagccattc
    41341 cgcagccaag tgctgcttca tacatcatga ttgctttttc tgtgttacca actaaaatac
    41401 tgacgatcgt tgctaaagca gtagagacaa ataaagcatt cccgacaccc cagccggcac
    41461 gtaacccaat cagcattccg atattcccag ataatccgcc aagaccagcg aatacaacga
    41521 tgataaacaa tcctgtcatc aatgtttttt caaaccgatc cgactagata agaaacctgt
    41581 aaatagcatc accacaccag tgactaacat gtaactagta aataacaggg tcgtttcagc
    41641 tggcgtagcg tttaactgtg cagcaatcgt ttttaagatt gggtctacta gacccactcc
    41701 cataaaagcg atcatacagg tagctgctac aactagcgct gaacttttcc cctttgtttc
    41761 ttcatttgtt tgttcttgta tatctatttg attctccaat atttccatcc ctttctctct
    41821 attagcatca tacatgattt attttacatg taaatatgca catgtaaaac gtggaaactt
    41881 tactgtgata taataaagaa aataagacga gaggtaggat ttttatgaat actttagcct
    41941 atatattatt atgcgtgctt ttatccaaac cacgttctgg gtatgaattg aagcagctga
    42001 tcacaatttt ttgggaagcc catcacagtc agatctatac aacgcttgcc aagttagacc
    42061 agcagggtta tgtgaccgtt ttggacaaag acgagcactc tcaaaaaaag atctaccact
    42121 tgactgatga aggacgtgct cttgtagagg aatggatcaa agaggaaact cccgctccta
    42181 cgcaaaaaga tgaatttcta gcaaaaatct atgctttttc gacgctcgat aaaacaacag
    42241 ctactggact gctattcact agagaacaac agctgaacaa aatcatgcaa aaaaatcaaa
    42301 aaaaattgaa tgacctctcg ctagacaaga aacaagaatt tggacgttat gttgtgatcc
    42361 agcgcagaat tatgctttgt cagcaggaac tccaatggtg tcagcaagta agagaacaaa
    42421 tgcagcagtt ttttgagtaa gggataaaca gaacctttct agaaatatct attgaagagc
    42481 aaattatctt caataaaaga gcaatacagt tggaaaagaa aaagcgatcc gaacgacagg
    42541 ccaaaaccta tcgttcggat cactattttt ctagaactgc attcaagaga ctatgacaaa
    42601 aagcatgcca aggccttttt tcaaataaca gtgttccatc attcattact ttgaattgct
    42661 tttagcacac ttcttgaaag cgggccaacg atgatcaact gcaacggtaa agcggcaatc
    42721 acattcattt tccaagcatt catataagca gagaataatt gatcaggtat tccttgttcc
    42781 atgatcacac cgaataaaga catacatgtc accattccta aaaccatcaa gcatgaaata
    42841 gttaagatca tttggacctt gctttctgga tttactggta gtttaaaggc aatttttttc
    42901 gccagcacac cgatgatgaa gacatccaaa atgaaagcca ccacgaatcc aggcactaga
    42961 ccaatcaaca aacttgataa atgaagatct tgatgcagcc ataaattata cgcgctcatc
    43021 cccaagacca tcaaaaaaca catcattgtt gtaaaaatta ttccttcttt tttatttgta
    43081 ggcaatctgt accactcctt taaatttgtc acgaaaatca tcgtagcaca tttaaaaatt
    43141 tctcgtaagt acttttttta ttttctgccc ttttatttca taaacttcat cagccgtacg
    43201 ctcgacaaag taagaatcat gagaagtaaa caaaatcgtt cccggatata tttgcattag
    43261 cttctctaaa gcttcgatcg ttgccatatc aataaaatta gtcggttcat ctaacagcaa
    43321 cacattactt ggcttagtaa aaagcaaagc aatcgtcaga cgggtcgctt ctcccccact
    43381 taatgtacat aacggtttcg tcaaagtttc ctgagcaaac cctaagtgat tcagcaaact
    43441 acggacaagc gattctgaaa actctgtttg tctcatgaca aaacgaatga tggattcttc
    43501 agatgtcatt tgataaccct tttgctgata tacttgaaag cttactttcg gagagagaag
    43561 gattccttct ccttgtttgc ggatatgttc taataaggtt gtcttacctg aaccattttc
    43621 accgacaatc gcgatttttt tacctaaaga aaactgaaaa tcaccattta ccagtaatgt
    43681 tctcccactt ctttccaatt ggacattttg tcccatgatg ggatagcggc tgtggagttc
    43741 aagagatttt ggtactggaa aacggatttg tttcatctgc tgcggcttgg ttgtttctcc
    43801 tattttttgg agtcttctct ctaatgtttt cgcattcttt tggatggctt tttgtacact
    43861 gtctttttgt ttagaggaag acaaccgatc cggtctgatt tgttgctttt tctttttact
    43921 ggacactttt tccaactttt ccgcttgttt tttcttttct tggatcgatt tttccaatcg
    43981 ttttttctct ttcatgatcg actctgcttc tcgtagctga gtctttttct ccaattcctt
    44041 ttgagtgaga taggcactat aattccccga aaactctcgg atttctccgt cttttacttc
    44101 ccagattttc gatgctagct catctagaaa atagcgatca tgactaacaa aaaccagcgt
    44161 accataataa taacgaagct cttcaatcag tcgatcaata ctttttctat ctagatgggt
    44221 tgttggctcg tctagaagca tcccttgttc ataagaagaa agaagacgta tcaactcgat
    44281 ctttcgttct tcccctccgc tccatttccg ctctgaagtt tcttccagtc ttaactggaa
    44341 atgactggct aattccaaat ttaggtcctt tgcttcagcg agataggtta attgaggcag
    44401 gtagttgaag gtgatctctg tttggatttt cccatgatcg ggaaaaagtt caccggctat
    44461 tagtttgagc aaagtcgatt taccgacacc attttctcct atgatcccta tacgatcttg
    44521 ctgatagaca cgaagagaat caatagatag ttctagctgg ttgccaaagc tgacttgtag
    44581 atttgttata tttactgcta aattttccat atgttttaca ctcctatttc atgtaaaaca
    44641 acaattatcg atactaaaaa agagcagaaa aatctgtttg caaaaaaact gcatcacatc
    44701 ttttcctact ctgaacgaaa taactatgac taaatcacca aatctgtcat agctttcacc
    44761 tattctactg tcgttcgaaa aaatggacat actccatcca tgaaattgtt gtttatacat
    44821 gtcttttgaa tttatttagt tgttattcaa aagttcgaaa cgtaatttca tcgatgcagt
    44881 catttttccg acctcctttt ttattaggtt accacacacg attcaaaaaa agcaatagct
    44941 actgaatagt aactgaaaac cttttattcg aacgtagtga tcttttctgg tgctaaacga
    45001 acagactcgt aaccttcttc taccgctttt cctattgata aaataataac tggaacataa
    45061 cggtctttat ccaaaccaaa tgcctctgcc aactgatctg cttcgaatcc accaattgga
    45121 tttgtttcat agccatgatc acgcgcaact aacatgaatt gcatagccgc taagctagaa
    45181 tcgactttga ctacatcgtt catttcttct cttgaaaaac tcttgtaata aggaatgatc
    45241 gcagctaatt gttgatctct gacttctttt ggcatcttcc ctgattcgta agcttggtta
    45301 tagatttctt cgccatattc gtaacattgc atatcgccaa aaatcatgac cattgcagaa
    45361 gaagtatcat tttgtctcgt attgaaacgg atcaaaggac gcaagatttc ttttgcttcc
    45421 tcgctttcag cgaccacaaa gcgccatggt tgcatattga cagaagaagg tgcagtcgtc
    45481 gcttctttga tcatttccag catttcttcg tgtgggattt tgtatgtttc atcatatacg
    45541 cgaacggatc ttctaccagt cataattgtt gaaaaatcat ttttttgttc cattattatt
    45601 aacctctttc gtttctgttg ttatattgca aagttgggta ttcaatttat ctaaaagtgt
    45661 tagaaattgt ttcatttcta catcgctgaa agccggggat agcacggaac ctgtatcttt
    45721 atggtccatt tcacaatgct cgattttctt ctgggctttt tctgttagcg ctacatacac
    45781 ttcccggttg ttctgaggat ttctctgacg cgaaacatag ccatttgctt ccaatacctt
    45841 cagatgacga gtaactgctc cttgatcaat ctgcaacttt tcttgcaaac tgctttgtag
    45901 caatggattt tcttctttca gtctcatcat gatctcgtat ctagtaagac ttataccgat
    45961 attttcttca aagatctgga cgattttttg atcggctaat ttgatttgat ataaaaggtg
    46021 actaatctct tctaaagaca taatttcctc ctttctaata attgactcgt caacgattga
    46081 cttgtcaata atagaataaa aaaagaaaaa agtcaaagaa tcagctgtgt aataaaaaaa
    46141 acgctctcaa tagaaaagta tagagaaaag aaattttttg tagaatgaac ggaaaaaatg
    46201 ataaagaaag cacaacgcta aaaccaagat tattgattct tatcaaacta tagaagatag
    46261 ctcttctgca gtagaaaatt ttacaccgcc aaaaatttcc gaaatcgcct tttgcaagaa
    46321 tcccgtcgaa tattagaaat tggatcagta tgcttaaaca gtaataaaaa agttatgaca
    46381 agatgttgtc acaacctttt ttgagtaaac ggtgttcaaa aacttgcatc tgcggtaata
    46441 agttcaacca aacaaaaaac atgaaaatct gtttttgttt ggctgttctt actacttgat
    46501 gcagggcagc tttttcacta cctcttttta ataaccataa aatcctattc cttcatatct
    46561 ccagcccatc ggtgttagcc aatctctttc cttagcactc aaggtatagt gatgggtacc
    46621 agttttttca tttggattaa atagtcgata aattggcttg gaaccaccag aataaaaact
    46681 tagaccttca taacgccaac cgatttttgt taaagagttg atctcagatt gtgccattgt
    46741 gtaatgatgg tctccactgt aaggattgta taaacggtag acaggttgtc cgctgtttgg
    46801 tgcttgccaa gcaatccctt catattccca gcctacagtt ggcagataat ttttttctcc
    46861 ggcattcaat gtatataaat gttctcctgt atgacggtta tacagacgat acatcggaga
    46921 agttgaagtt ggtgctgtat catactgtgt cagattatag gtttcgatta cattgttcaa
    46981 tgtagaacca taattaggcg cagtggcata acgacctgtt agccaagccg tagcatcttt
    47041 gtaagagttc gtattgcttt tccatgcacc ggaatagtag taaacgcctg gctgaaaaga
    47101 agtcgtcttc aataccgtta cgttatcttg caatgattct ttgtacgaag gatattttct
    47161 aaaagcggca ttcaccgtaa tccattgccc attcacatat tccgaagtag gcatcgtaac
    47221 agattggcca ttatagcttc ctttaatccc aaatagattg taattagggg cagaagccaa
    47281 agtactgttc ccccagccac tttcaacgat ggcttgagca atcatgactg atgcatataa
    47341 gtcattggca cttgccaaac tttgtgcagt tgaggcaata ctatcaatga acgcttgttg
    47401 agaattagca gatgagcgag cataaaaagc atagccagta tagttttcga attcagacaa
    47461 atctgcttga tgggtatgtg tcaatgtttg cccatctgtc aattggttcg tgatttcttc
    47521 tgcattctct ggattgttct gagcttctgc tgatgtactg tcttcggttt gtgtttgttc
    47581 tgttgtttca gttgttggtt cttcggttga aattgtattt tctgagacag tagctgactg
    47641 caaagtactc tctgtatcgt tttcaattcc tgtttctgaa gaactcgatg tctgagttgc
    47701 gacagtttct gtcgattctt cagctagcac tgttgtgttg gcaactgcta gatttcctaa
    47761 aagaataacg ctaaataata aattctttgc tttcatcttt tttctccttt gaattatgaa
    47821 acttttccta aataacagtg taactaaaaa agtaaaagca agtcaatgtc catatttaaa
    47881 taacatttgt ttctttttga taaatttgct ttttctacat aaaaagacgt aaatgaagaa
    47941 tattcttctc cattcacgcc ttaaattgat ggtcgtttga ataactattt aacaagtaat
    48001 tctctttgga tattatccgt tatggattat acttcctgtg tcgtcggacg gataatcatg
    48061 ttactgacag acatccggtc tggcgtttct atcgcaaatg ctacagcaga agctatatct
    48121 tcggaggtca atccccattc tttttgcgct tcatgaagtt caagagcagc ctttttgtcg
    48181 ctgatggttt gatataattc agtttgaaca gctcctggag agatgatcgt agatttgatg
    48241 ttattttgcc gttgctcttg acgtaatcct tccatgattg cacggacagc aaattttgtt
    48301 ccgcaataaa cggcggaatc aggataaaca acatgtcccg ccacagaatc agttgaaatg
    48361 atatgcccag atttttgttt ttccatgatt ggaagtacgg cggaaattcc atttaacaca
    48421 cccatgatgt tgatatcaag catattttgc cattcatcac ggtgaccttc aactaatgga
    48481 gcggttggca tgattcctgc attattgtac aatacatcga ttcgaccgaa cttttccatc
    48541 gctaaatcga taactgcttg gacttgtgca aaatctctta catctgctgt ttgaatatat
    48601 agctcagctt ctggtaaaga ttcttttatt gcttttaggc gatcttctcg gcgtgcagct
    48661 ataactagtt tagccccttt ttctgctaat agcttcgttg ttgcttcacc gattccgctt
    48721 gaagcgccca tgatgacaat cactttttct gataaatcat tcattctatt ctcctcctgt
    48781 tttgaaaaat ctcttgctta tactcactat ctcttatttc atcttactgt tcaaataatc
    48841 cgttcgacag gtttgacgat tttggcaggg attcctgcaa cgatggtatt gtctgggaca
    48901 tctttcgtaa cagttgcatt cgctgcaaca atggcattct cgccaatcgt tacgcctggc
    48961 agaatagttg ctcctgctcc gatccaagca tttttcttga tgtggattgg ctttactgac
    49021 aagcctcttc gttcttttgg atcggttaga tggttcaccg tgatgaggtt gacacgagga
    49081 ccaatcaata ctgaatcttc taaacagatg ccacctaagt caacgaacat cacttgacga
    49141 ttgataaaga catttttccc tatactaata tgtttgccga aatctgtata aaaaggcagc
    49201 agaacagtca ccgtatcatc tactttgtca ctaatgatat tttctagccg tttgcggata
    49261 tctgctggtt catggtaccc agtattcagc gctgctaaag gctcttcgtt ttcagcttgg
    49321 atctgatgga tcacttcaaa gagcggatcc gttactcgaa tctctttatt gacgatttgt
    49381 ttttcgatga ggcttgtcat tttgctccct ccttttatcc ttactttata acggacggct
    49441 tatcatgtct aatacttata aaacatactt aactattcct tttaactata cttagtggta
    49501 tgctttttta aaaacaggag ggaaaaaatg gatattcgta tactgacgta ttttttagca
    49561 gtagctagag aaaaaaatat cagccgagca gcaaaatctc tgcatatcac gcaacctact
    49621 ctctcaaaac aactgaaaga tttagaagaa gaacttggtg tgacactttt cactcggggc
    49681 tcccgagaga tacagttgac ggattctggt cgatatcttt attcaaaagg aaaagaaatc
    49741 ttgtcgttgg tagaaaaaac ggcgaacaat ttaacaaatg acgcaatcat ctctggagaa
    49801 atctacattg gcggaggcga aactaaagca atctctttca tttctgatag ccttcattcg
    49861 ttgatcaagg cgcatcctga tatccagttt catttatata gcgggaatgc agatgatatc
    49921 atagacaaac tggatagcgg attacttgat tttggactcg taatcgaacc gacaaacaaa
    49981 caaaaatacc agtcatttcg actgccagcc caagatcgtt ggggactttt gatacatcga
    50041 aatcatcctt tagcaaagca aaccgtcatc catccgcagg aactgaaaac tgttcctttg
    50101 atcatttccc ggcaaacgtc agtggacagt caactagctg aatggctagg tttcagcata
    50161 gatcagttat cgatcgtcgg aacatataac ttattgtaca atgcttcttt gatggtcgat
    50221 aacgggactt ttggtgcatt agctctagat gggatcatca atacttatgg gacggaaaaa
    50281 atattcatcc cactcgatcc gccattacaa gcttcactga atctcatttg gaaaaaagac
    50341 cagcctcttt ctcctgctgc tcgtaaattt ttagatgtcc taacggagaa atacagttaa
    50401 gtagagtttt tttccttcgc tttcagcttt ttaacaacga ataagataag caaaagatcc
    50461 aacgattaaa taacataagt ttcttaattt atttcttcct tttatttctg ataattccag
    50521 taaattacta taattataaa aaaagaattg acaaaacata actgtctata taaaattgat
    50581 tacgttaaca ataattcgtt tcatgtgact agatcatact aggcatgaaa aatctctgag
    50641 gaacatggtt tccctaggag gtttttcgtg tctatttttg tttggccgca atcaactggt
    50701 ctagcaaacg tgaaaaccaa atcttcaaaa agggtgcgcg catgaaaatc aaaaagatct
    50761 ttaatcaaaa tgcagtattg gtagatgacg gtggacagga aaaagtagct attggaaaag
    50821 ggattggatt tgacagaaaa agaaatgatt tgatttttga tcgtgatgtc gaacggatat
    50881 ttgtcatgga accagaaggt caaatcaagt tgcaaaattt acttaatcag attgatgaac
    50941 gctttttatt tgcagcagaa acgatcattg atcatgcgga aactgttttg atggaaaagt
    51001 tgaatgaaca tgtattgatc gctttgaccg accacattgc tttttctgcg gagaacatta
    51061 ataacggtat cgtcatccgc aacaaacttt taagagaaat cgaagtgctt tacagtgatg
    51121 aattcagtat tgctcaatgg gcagtagagt atctgacaaa agagcttggg attccatata
    51181 cttatgacga agcaggatat atcgcaatcc atattcacag cggacgaagc ggtcggaaca
    51241 ataaccatcg cagtatccgt gaagtgacga ttgtatctga catcatccat ttagtggaat
    51301 cagaattgga aacagatatc cattcagaac cattttcact gaattattca agactggtga
    51361 atcatttacg actgcttcta caacgaaccc atgcgcaaca atatgctgtt ttagacacgg
    51421 aaatcgtaga aatggtcaaa cgaaaatacc cagaaagcta taagatttct aaaaaaatcc
    51481 gtgtgttgct gaccaaagaa taccagctcg cgatcacgaa agaagaactg ggttacttgg
    51541 ccatccatat cgagcgttta agaagcgcaa tcgtacaaac aaatgttaac aatcatgagg
    51601 aggaaaaaaa ttgaaagcat atctacaacg aatgggacgt tcccttcaac ttccagttgc
    51661 ggtcttacct gctgctgctt tactagtagg gatcggaaac tggtgggcat cttatagtaa
    51721 cgacattgtc gctcattttt tacaagctgg cggtaacgca gttttaggtc aattaccttt
    51781 gctgtttgcc gttgggttag cactagggat gtcagtggac aaatcaggtg ctgctgcctt
    51841 ggcaggtttg gtcgcatttg aagttccagt aaatgtttta aaaactgatt cagtagctac
    51901 tttattgaat atcaaaccag aatcagttga tccatctttt gctcagatca gtaacgtatt
    51961 tattggtatt attgccggat tgattgcggc agctctttat aatcgtttcc acgaagcaaa
    52021 attaccgatg gctttatctt tctttagcgg caagcgtcta gtgccaatct tggctgcctt
    52081 tgtcatgttg ctgatcagtg cagtgctact gctcgtatgg cctccggttt actctgcttt
    52141 agtttctttt gctaaattca ttttgagttt aggctggggt ggtgcaggtc tttatggctt
    52201 cttcaaccgt ttactgatcc ctacaggatt gcatcaagca atgaactccg tgttctggtt
    52261 tgacgtagca ggaatcaatg atattggtaa atttttggct tctgaaggaa caaaaggcgt
    52321 aacaggaatg tatcaagctg gatttttccc aatcatgatg ttcgggcttc cagcaggagc
    52381 atatgctatt tacagaaatg cacgtccaga aaacaaagca aaaacagctt ccttgatgct
    52441 agcagcagct tttgcttcat tctttactgg tgtgacagaa ccacttgaat tttcatttat
    52501 gttcgttgct tggccattat atgtcttgca tgcaattttc actgggattt ctttagcagt
    52561 gagtgcattc ttccattgga cagcaggatt tgcctttagt gccggatttg tcgattactt
    52621 cctatctttg aaaaatccga ttgcgaatca gccattgatg ttgatcgtcc aaggattagt
    52681 aacagcagtg atttactact ttggctttaa ctttgctatc aaaaaattcc atctgatgac
    52741 tcctggccgc gaggaagcag atctttcaga tgacgatact gcaacgacta attcagacaa
    52801 taaatatgcg gcacaagcaa gcaaaatcta cgctgcatta ggcggagccg acaatgtaac
    52861 ttcgatcgat aactgtacta cacgccttcg tttgcaagtc aaagatacag gcctgatcga
    52921 tcaaaataaa atcaaagcca ctggcgtacc tggtatgaag atcatcgacg gaaaaaatgc
    52981 gcaagtcatc gtaggtacag aagtacaatt cgttgcagat gagatggcaa aactacatgg
    53041 tggtgctgca gcacgacctg cacaaacaaa caccgtggtt aaaacagaaa catttgccgg
    53101 tgaaacgatc gaacaagata tttacgctat cgcaaatggg aaactgattc caatcactga
    53161 agtttcagat gatgtattcg cggaaaaaat gatgggtgac ggctatgctg tattaccaga
    53221 aaatggagaa atcttctctc caatcgctgg tacgatcaca aacattttcc caacgaaaca
    53281 tgctgtcgga atccaaacag atgctggtat cgaagtcttg cttcatatgg gcatcaacac
    53341 tgttgactta aaaggcgaac cattcacttt atatgtagaa gaaggtcaaa aagtcgcaag
    53401 aggtcaattg attgctttag ttgatcttgc cgctattcaa tctgcaggca aaaacacgga
    53461 tatggtcgtt gtattcacaa atggcgacaa agtccaaagc ttagaaatcg aacccgcacg
    53521 tgatgtaaaa gcaaatgata aaatcggctc tgtttccaac aaagcctgag ccatcgtctt
    53581 ccccagactt ttttatcgat aaacaaacag gagctgagac aaaaatcttg tctcagctcc
    53641 tttttccgaa taaaaacggc gttctcctgc caactccgcg gtaataagtc cagctaaacg
    53701 aaacatatga agagctattt tttatttgac tcttcttatt acttgatgca gaacagcttt
    53761 ttcacaaaat ttttcttcat actcaaaact aatcggcttt ttcacaacct ctttatacat
    53821 tattcctgat ccaatatttc ttttaatgct gcttcaagag aagttaatgg ttttcccaat
    53881 actttttcta aatcatcaga ggaaatagct aactgatcct ttttaatatc atgttggatc
    53941 gctaaaaaca tgtcagctgc ttcttgaggg aatccggctt cttttagatt ttcgacaaac
    54001 gctgcatcac ttgcttcaat aatttctaac tctttacctg tcgcacgctc taatgccttg
    54061 gctaattctt catagtcagt tagattgccg gataattcta agatttctgg agagtcactt
    54121 tctactagta cttttgctgc agcttctgca tattcacgtt tcaatgccca acctgttttt
    54181 ccatttcctg cagcataaac gaattgacca gtttttaaag cctgcccaat gataggtaat
    54241 tcattctcta cataccaatt attccgtaaa aatgtatggg aaatacctga atccttaatc
    54301 attttttcag tgaattggtg atctggcgct aatacactga tcgagtgatc ggcatctgca
    54361 aaacttgtat aagcgatata agatacccca gctgcttgtg ctgccttcac tacattctta
    54421 tgttcggctt gacgatttcc tggaacgcca gagacaaaaa gcaatcgatc tattcctttc
    54481 aacgcttctt tcattgagtc taaatcatca taatcaccaa tacgtatatt aaatccagct
    54541 tctttcagtg cttctccttt ttcttcacta cgtactagta catagatttc attttgtgga
    54601 accatctttt ttaagaattc cagcgcataa ccaccaaaac ctccagttgc tcctgttact
    54661 aaataatgca tatttgccac tccctattct ttttatttgt taagatttac agctgtacat
    54721 ttataaatta cacctttatc ataaagagtg tggtaagata agtcaagcaa aaaaaatgaa
    54781 aggatgacaa ctgatgaagt attctctgca atttagtgat gcaatccatg tacttgccta
    54841 tattgaaatg tttcaagata cccgatcact ttctagtgag atgattgcca gtagtatcga
    54901 aacaaatgca gcaaatgtac gtaaaatcat gagtcagctc aaaaaatccg gtttgatctt
    54961 tacaaaaacc ggaaaaccgc agccttccct tgccaaaagt ccagatcaga tttctttact
    55021 agatgtctat cgcagcatcg aaggtaatac acagcttatc caagtcgatc caaaaacaaa
    55081 tccaaattgc gtcgttggtg cgaatatcca agaagcttta gaagaaagct acgctcggct
    55141 gcagaaaaag gcagaagaag aaatggctaa gatcacactt gatagtctga tacataaaat
    55201 agccgttttg gaaaaagaaa aaagaccaga aaacacaggc ctcgtagaga gatttttata
    55261 attctctcta ctgtgcctgc atttttctga tcggaatcgt ctacataaat tcttttattc
    55321 tccgggggac aaaagccttg tcatgcccct ttttcctctc taatgctcag gtcaaagcgc
    55381 tgaagtcatg acgtcttgat aaacggtgtt caagtagctg accctcggca ttagttctga
    55441 aaaatgcaaa atatggaaag ctatttccca tttttcctct ctaatgctca ggtcaaagcg
    55501 ctactttcac gacctctata ttatcatggt ttattgacta ccggtatcca gatttctccc
    55561 atatatttcc cgttggtaac tcccatttcg actacagcat ttggaccccc aacataggcg
    55621 taatcttcta cttctcttaa aacatgccca aaggccgtat tcgtcaaatc atttcttaat
    55681 tcttcaggcg attctgctaa agcgcttaca acaagatacg ttccttttgg gaatgggatg
    55741 attcgcgtag tgtttggaac atcctgactc gtttgaacac cgacatagta catcattttc
    55801 ccgttatagg gttcgttgac tgtaaagaaa taatgatttt cagcagcttg tttcaatgca
    55861 tctattgttc cattaccgat aactttttgc tcaaatgctt gtttctctgc agccaaaccg
    55921 acaaaatccg tattgctact cttcaattcc acaccaatac ccgtcaccgt aaaatctggt
    55981 ttttcttcga tcctatactt tgccatttct cccacccttt ctattatatt aagttcatct
    56041 tacataaaat taaagggaaa tgacacgatt acgctctttt ttctagggat atttttattt
    56101 tttaactatt tttttgcttt cactgcaatc caaatctcac tgtaaacatt actgaaatcc
    56161 tctccccatt ttgtaaaaga gatctcggga gcttcgacta acccataatc tgaagaagga
    56221 agccattctg catagatttt cccccaagta tcttgtaaag tttggggaaa tggcccttta
    56281 ttaggaaaaa tggcccaagt gtgttcttct atagcaagca tttctaaatc agcgtacgga
    56341 ttttcttttg tcgtagcaaa gccaatcatg tgcatcaaac tgcccttttc ttccaagcgg
    56401 tctccatcaa atccataaga aacgttgatt acttgatttg gatataaatc tcctaactta
    56461 tgcatctctt ccctttgagt ctccgtgatc gtctgcgcta acttttgtat ttcttgattg
    56521 actccttcaa atttgacagg aacttttttc gccacacctg ccacataaaa ctgttctttc
    56581 ttttcgatac gaaattccat cgattttcct cctctgacat caataaaaaa tgtcaagcgt
    56641 ggaaaagatt tttgtatgcc gtatctactg atttctgaag gcagatatcc tgaccaatca
    56701 cgaaaagctc ttgaaaaacc ttcgactgtt tcatatccat atctaaacgc cgtttctgtc
    56761 actcttgatc catctagaag atcgcgatta gccaaagcca atctacggtt tttgatatag
    56821 tccattagcg acatccctgc aataaacgta aagatgcgtt ttaattgata ttcagagatt
    56881 cctgtatttt cggctattat tttataggaa agtccttctg tcaaatgttc ttcgatgtaa
    56941 tcgatcaatt ggttcagatc tttaagcata tttatcttcc tccttgattg cctttttatc
    57001 atattatcaa agaaagtcaa ttacttgatg aatcaggaac caatttagtc agatgtagaa
    57061 aatgttgtat ggatctaaag aaaattctca agcagcgttt cgtaacggat aattggtatt
    57121 atctgcctat ctatgtttta cctttagaaa aataaatttt ggggaagaca gattctaagt
    57181 aaacaaagcg gtaaaaatat cttttattcc cttagttaat ccgcttacta cctactgtac
    57241 aaagcaaatt gttgttcaaa ctgctgatca gaacgctgct tggatttttc tttgcgatac
    57301 atcatacctc ttttatcaat tggaacaatt atttatttct aacaaaatca cttcattttt
    57361 gtcagataaa taaaaaacaa aaaaagttcc atctttaaaa cacgctattc ttttactttt
    57421 tctcacattc tctaagaaaa gaaaaggaga atgaattttt gacaattcga gcaaaagtga
    57481 ttatcaaata tgtaaaatca gctacttttt tcttaaacgt ttctttatac taaatataaa
    57541 taagtgtttc atgaaaggag aactagatga ataattggct tgagtatttt cctgaaaacg
    57601 ttttggaacg cggttacagc tatcatctgc acggttttgt ccgtcatttg aactatacaa
    57661 gcaagtactt gtccgcaaca gtttctggca cggaagatta taaggtagtg atcacttggg
    57721 atgaaaagac caacatgact tgtgattgtc tatatgccat agaaggaaaa aaatgcaaac
    57781 acatggctgc tgtcttattc gcttacgaag aacgtccaat aaaaaaatcc aactactcac
    57841 tttccgaact ctcgtccctt gtttcctccg ctagttcctc tcttgtacgg gagcttttaa
    57901 cagagattct tatagaacat ccgcacttta tcgaacgctt caaagttaag atgccatttc
    57961 atgcaataaa ttattcagat aaattaacaa ctatcatcca taaatacgat catattatca
    58021 agaaaaacaa aaacaggaaa acagcgaagt tcatcatgga gatgcgaaag ttcatccaag
    58081 aagcagttga atcgcttatt cagcaaaatg cctatcttcc cgcattcgaa ttgatcaatg
    58141 aagtgattgc tactctcgaa acattctatt gggagcctga ggatgaacga acccttcttc
    58201 tgatagagga ctgttattat ttatggaaag aattattagc agaagcacct catgcagaaa
    58261 aaaggcaaat gttctcttgg ttcgtctgcc aagtcgatca tactgacgcc tcttattcaa
    58321 aacgctactc tataaaaatc ctgaaagaag actttcggga aaaagaattt tctaaccaaa
    58381 agaaaaaaat agataaaaaa ctaaagaaac ggtaaagaaa gacgatttca atgaaaaata
    58441 gcaagtaaac gataacaacc atcctaaatc cacaagaaat acagcagacc ttgctttaaa
    58501 aacacgaatc atgcaaagga tgaagtaaag aagacttaac gcgtacccaa tattagtcat
    58561 ttgactatta ggtacgcgtt ttgttttata agtcatgaca aatttccttc gttgctggat
    58621 agattttccg gcattgttga tagattttat gatacttttc tacattttgt aagagaggtt
    58681 ccgctgcatc tgtatattgg ataaaattct gacaacaact ttcaggtgtg tcgaaccacc
    58741 ctaaccctag tgcagcaatc attgttgcgc ctaatgcagg tccttcctcc atacttaaac
    58801 aatagaccgt tgcatcgaaa atatcagctt ggatttgtag ccatgcaaga tttttcgcgc
    58861 ctcctcccac cgaaacaata cgtgtaaatc tgcgacccgc tagttcttta cgtttcaatc
    58921 ccaccattga caaatgctca ttaaaaattt agaatattca caagtttaac gacaattatg
    58981 aaaatttatg tcgtgctaaa ggagttttgt tattggatga aaagttagat ataaaaactg
    59041 cgatcaaaga cacgttacct accgttttcg gttatatcgg tattggactt gcatttggta
    59101 tcgttgggaa agctgccgga tttcatccac tagtcgtcac gttgatgtcc ctgctggtct
    59161 atgctggttc tgcccaattt atcacagtca gcatgcttgc tagtcacagc ccattgcttt
    59221 ccatcgtttt ctcgaccttt ctagtcaatt cccgaatgat tctgatgagt atgacgattg
    59281 ctccttattt caagaaaaat cggctgcttc aaaatctgct gattggcaca ttgctgacag
    59341 atgaaagttt cgcactggga atgaataaat tgaactatac tggacaaaag ttaaactttc
    59401 gttggatgaa tacagctaat tggatttctt atttgacgtg ggtgggttct tctcttgttg
    59461 gcgcactttt agggaatttt attactgatc cgaaaaagtt tggtttggat ttcgccatcg
    59521 tcgctatgtt tatcgggtta ctttatcttc aagtcatttc tgatagaaac acctctaaac
    59581 gattacagtt gatcctgatt ggtctcactt tgattctggt atatgtcgga ctgattttta
    59641 tcccaagcaa cttagtgatt gtagttgtaa cactgattgg gtgcggattg ggggtgtgga
    59701 tcaaacatgc cttcttttga gtttacattg ctgactattt taggttgtac tttagcaact
    59761 tggctttcta gggtcctacc atttgtctta ctgaaaaaat tcgatttacc gcaaccgttg
    59821 cttgagtatt taagttttgt cccgatcgtc attatgtctg ctttatggtt cagcagtcta
    59881 tttacccaaa atatcggaca tctgccgcag atcaatctcg aaaatgcttt ggcttcagtt
    59941 cctacacttt tagctgctat tctttcaaaa agcttattgg tgatcgtctt ggcaggaatt
    60001 ctttcccttt cgttgattcg cttattataa ataaaaaaac aagagcttat ggcaaattac
    60061 tgtcatgcgc tcttgttttt atcaaagtca aataagaaaa aaatcggcgt attcttgctt
    60121 atccgttgaa cggaccacta acaacgactt ttcctaacat atgtcctgtt tctacgtctt
    60181 tggttgcttg tttcaagttc ttcgcattca tcccatctga atagaccttg ctcaatgtac
    60241 tgcggataat cccttcattt gctaaagcag caatgtgcgc taaagcttct ccttgcgttt
    60301 cgatttcata gttatagtct gttttagcga acatatactc ccagtcgaag ctgatagatt
    60361 ggtttttcca aacacctata tctaacggct ctttgatccc tacgatcgtt cccacatgtc
    60421 caaatggtcg gacaaggtgc ttgatttgat caaagtagcg ggtaatatcg aataatacag
    60481 cgacatactc tacttgatcg attcctaatt cacgaaaact tttacttaag tcgtgatgat
    60541 aatcgattgg atagtctaca cctgtttttt tcagccattc aaaattcttc ggacttgcag
    60601 tcgcgtagac ttctaggcca gcccaatgcg ctagttgatt caaaatcgaa ccgacgcccc
    60661 cggatccgtt gatcactaag atttttttcc cgcgattggc attttcttct ggagttagac
    60721 caaatttttc aaataacaat tcataagcgg tcaatgaggt caacggcaag gctgcagctt
    60781 cttcatctga aagatttttt ggtgcaagag cgacaatacg ttcgtcaact agttggtatt
    60841 cttgattgct tcctgctctt gttgttgtac ctgcgtaaaa aacgcgatcg ccgacagaaa
    60901 atttttgcac ttcgtcacct acagcaacaa ctttcccgac tccatcaaaa cctaagatac
    60961 gtaaagcatt tcttatcccg ttatcttggc gaagtttcgt atcgacagga ttaacagata
    61021 ctgcgttgac ttttaccaga agatcccgtg aactgggtac aggtatctgt tctttttcat
    61081 caataaagct ttttggatca tcgatcggca acccttcata aaaaccgact accttcatta
    61141 attccttttc tgacatacga attcctcctt agcttcatca agttggagca tccatacagt
    61201 gttcatttca atatatatag tatgctattt gttccacctt ttttattcat cataattatt
    61261 ctcttactta aagtaaacta tttgcacttt tttggttaaa aaagaggttg cgacaagact
    61321 tttgtcacaa cctcttataa acggtgttct cctaccaact cttcggtcac aagtcaaaat
    61381 attcatcaaa catgagaagc tgttttttga aattgctcct tgtgactcag agttaaacgg
    61441 caggctcaca acctctgata taaacggtgt tcaatcaact gaccctcggt attagctcaa
    61501 aaaacgacaa aatatgaaga gctatttttg tttggctgtt cttattactt gatacaggac
    61561 agctttttca cgacctctaa ttcacggtgt tcaagcaaga aatcattgtt cactgaaaag
    61621 cgttggatgt tctttttcaa aggtctctaa gatctctcgt acttcatcag tagatttcgt
    61681 attcatcaac tgaactcgca agtcatttgc tcctggaaat cctttgatat agattttaaa
    61741 gaaacgatgt agtcctgtga tggaacgcgg gatgatttct gaataatgat cttgcagatc
    61801 tagttgcaga cgaagtagtc cgatcagttc tttttctgta tgttccctcg ggtctttttc
    61861 aaatgcataa ggattcttga aaatccctcg gccaatcatg atgccatcaa cgccatattt
    61921 ctcggccaat tcttctcctg tctggcgatc ggggatatct ccattgatcg tgattagtgt
    61981 ttgtggagcg atttggtcac gtaaagcaat gattttagga atgacttccc aatgtgcatc
    62041 tactttactc atctctttac gcgtacgcaa atggacagaa agattggcta tatcttgatg
    62101 aagtaggtga ctgatccatt cttccatctc agacatttcc gtatagccga tacgcgtctt
    62161 gacgctgaca ggcaaaccgc cagctttagc tgcttcaatc aattgtgccg ctacttctgg
    62221 acgaaggatc aagccactgc cttttccacg ttctgctaca ttagggactg ggcagcccat
    62281 gttgatatcg attccttgga agcccatttc tgccatagca atgctcattt ctctaaaaaa
    62341 ttctggcttg tctccccaaa tatgggcaac catcggctgt tcatcttctg taaatgttaa
    62401 tcttcctcgt acactgtctt ttccatctgg atgacagaaa ctgtctgagt ttgtaaactc
    62461 agtaaagaag acatccggtg ctgctgcatg ctttacgaca tggcgaaata caacatctgt
    62521 tacatcttcc attggtgcta aaacaaaaaa aggctttggc agctctttcc aaaaattagt
    62581 agtcatttat ttgttactct ccattctatc aagcagtgaa gtcgcaatct ttctcaaaaa
    62641 cattgtcatt atactaggaa acaaaaaaag aagcaaagtg aacagcttaa aagatgtttc
    62701 tgattgagca aaaaaaagac tgtgacaaaa atcttatcac agtccatttt ccggaataaa
    62761 tggtgttcaa aagcttgcat ttgcggtaat aagtccaacc aaacgaaaaa taggaggagc
    62821 tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca acctctccac
    62881 taaacggtgt tcaatcagct gaccctcggt attcgctcaa aaaacaacaa aatatgagga
    62941 actattttcc cgtttgtttc tctaatactc aggtcaaaac gctgatttca caacctcttt
    63001 tctaacttct caatcctctt cctttattga tcaaatacca agtaacggcg tacaaaacaa
    63061 cgatgaataa cacaagtacg atcatcgatg ttgctactgg cacatcgatc gttccaagga
    63121 atccgtaacg gaaaccggag atcatataaa cgatcggatt gacttttgaa acagcttgcc
    63181 aaaagggcgg taacatagag atggcataga aaacgccacc tagataagtt aacggctgca
    63241 agacaaatgt aggcacgatc gatacatcat cataagactg agcaaaaatc ccgttgagca
    63301 gtcctgctaa tgaaaacaag attgccgtca tcaataatgt aatgatgacc atgaaccatg
    63361 aatacacatg aagtggtaca aagaacaagg aaatgatcgt tacgagagag ccgacgagaa
    63421 tactgcgacc cacaccacca atcacaaagc cccaaataat cacatgcgta ggaacaggtg
    63481 ctaccaagat ttcttcgata tttttctgaa atttttgaga gaagaaggac gaagaaacat
    63541 tggcatacga actagtgata gcagacatca taatcaaacc aggaacgatg aattccatat
    63601 atgaaaaacc acccatgtca ccgatccgcc caccgatcat ttttccgaaa ataacaaaat
    63661 acaaggatgt cgtgatcact ggcggaacca gtgtttggac ccatatacgc aaatagcggt
    63721 tcgtttcctt gatagctaaa ctttttaatg cagtaaaata aagattaaac atttttctcc
    63781 tccgtatgat tattttcttc tgtgattttc aagaacagtt cttctaaacg attcgactta
    63841 ttcctcatag aaagaacttt gattccttgt cttgtaagct gatcgaagat tccgttcacc
    63901 ccttgatttc gttcaacttc gacagcgatt gtctgctcat cttcaaatgt acaagcatat
    63961 ccttcaatca caggtttggt atcatatggc gctaaatcaa agataaatgt ttcaaattgc
    64021 agttttgaca gaagctcttt catacttgta ttctcgatca gttcacccga ttggatgatt
    64081 ccgatgttgc gacaaagcat ttcagcttct tctagataat gcgtcgtcaa aatgatcgtt
    64141 gtaccatttt cgttcaattc tcgtagaaac tcccacatct cgcgtctcaa ctcgatgtca
    64201 actcctgctg ttggttcatc caagatcagc aaacgtggtt catgcatcaa tgccctagca
    64261 atcatcagtc ttcgcttcat tcccccggaa agcatacgtg cacggacatt tctcttttcc
    64321 caaagattgg actgcttcaa atatttttcg ctgcgtttca tcgcttcttt gcgagagaca
    64381 ccgtagtagc ctgcttgatt cacgacgatt tgctggaccg tttcaaaagg gttaaaattg
    64441 aactcttgtg gaaccaatcc aatctgttgc tttgctcgaa ctagatcctt gtccagatca
    64501 taaccgaaga cattcacttt tccagatgtt ttattgacta aagaagtaat aatcccgatc
    64561 gttgtagact tcccagctcc atttggccct aatagcgcat agaaatctcc ttctttcacc
    64621 gaaagatcga ttccccgcaa tgcttcgacc ccacttccat agatcttttt caaattattt
    64681 atttcaagcg catttgccat ttatttccta tctccttata gacatgattc ttaattgtat
    64741 catggaatac agcagatgaa aaaacaactt ggcttccaca caaaaacaca cctgctaaca
    64801 aagaggagat gtgttttcta gttcatgatc atcttcgata gaataactat ctaaacaact
    64861 ctggaacttt taaaatcata aaagtaccga cagcaactac tacgatgaca tatagaagat
    64921 ccttataact gaggttcttg tcttttttat tcatgttaag ctttcctccg tccttttatc
    64981 gaaagctttt ttcttttatt ttaaccgaaa taaataaaat ggaaatagtt attttcaatt
    65041 tctgttttcg ctgtttgttt tacggagaac tttgccatgg aacgtgcgtc tcgtcgctga
    65101 tgctaagttt tttcgataaa agctgctaga aggaagacag cgtggtttat tttgtatcgt
    65161 cttttgctaa atcttccaag atcatctgga cagcagactc gttcccattg aattctgcca
    65221 cttttttggc atcaatgtac ttcttttgat aatcgtcttt ttggacccac gcatcatgct
    65281 tcgtttgata aagttaatca aacggatacc actgacgctg ttcatcgaac aacaaacttt
    65341 ctttttgggc ctgttcaact atggatttag gataattcaa aactttcagc aaggcaatcg
    65401 catttcgggt ccttgaaggt ccttctttta atttgaaatc aaaactgatt ccttttcctt
    65461 ctgttacttg ttcttcaaag tggacattct cacaataatt ctttaaaatc tctgtcaatt
    65521 cgatatcatg tgtggcgaca aatgctaaag atggatactc cgcaagccac cgaacgactg
    65581 aagcggaaga agcaatccgt tcgatcgtat ttgttccttt taaaatctca tctacgaagc
    65641 agtagcagcg ttctttggaa gccacttggt ccagcaaacg tttgatcgat ttgatttctg
    65701 aaacaaaata actgtcgcct tcaaataaat catcttcgat tgccatggaa gtcaacacat
    65761 gtccaggttg cagggtaaac tgttctgcaa tcgctgtttg gatcgtctgt gctagaatac
    65821 agctgatggc tatacttttg acatacgtag attttcctga tgcattggaa cccgtgacta
    65881 atgtattctt ctgccagttg actggattaa ctaccgcttc ttttaacaat ggatgataga
    65941 tatctttcgc tgtcacaccg ccctcagtaa actctggtcg gcaagtgatc ggcatatagg
    66001 tgcgataatt caaaacggct gctgcaactt ccaattctcc cagcaattcc cacagcttga
    66061 tggcttcagt tgaatgcttt tctaatttag tgagaacgaa atgataggag ataaatggca
    66121 gcatgaacat gatgttgaca tattcaaaaa tcaattctgc ttcactcccg ctcttcattc
    66181 gaaatgaaaa acctaattta gggatgtctc ttaatggttt agtttgctgt ttcagctctt
    66241 tttgaagtgg tgtcgtcatt tttgctaact gattggcggc tgaaatcgtt gaaaccaaat
    66301 aactcatgct attcagctct gtttctagtg tttgtttctt cactagataa tagaccgtat
    66361 tgaatactaa gccaccgatt gctagataga ttcctagtac ttgccctaaa agaagcaaac
    66421 ctacacccac cagcggaagc aagccaagaa aaataaataa acctacgcgt ccaatctttt
    66481 tactttttcc atccgctaga tattgttttg caaaattatg atcttttttt cctaaacgag
    66541 cgaattgata ttggattctt tctctcagtt gaggattttc ctgataaaaa gcaattagtt
    66601 tttctaactg ataatcttct ccaaaatcaa agctacgtaa acgctgatac aacgcttctg
    66661 aacctacact agaataggta ctgttgatcc cttcaaatac ttcgaacata tccaagtcat
    66721 accaagtaag atcgtcgatt tcactatccc atgaacggaa ttttttctcc gtgagccacg
    66781 catccttcaa actttcttct ttatcaaatc tcggttgata aggaattttt ccccaattac
    66841 tacgaactgt ttcctttact ttcaaacgtg aaaaaatgtc taaaacaact aataaaataa
    66901 caactgcaat aataattaaa acgataaatt ctctttggcc catatccctc tccgttcctt
    66961 gatttgttag ttttagtata gcactgttgc gctatttgaa aagggggtac aaaaataact
    67021 gtcttcgtta cctaattcgt atcaatcaca ccaaaataaa aacaccttcc aaaaaagaag
    67081 atgtctttaa aacgagatac aattttttgt cattcacttc aggtaaatta gagccaatta
    67141 aaccctccgc aacttgacgg agatggagaa gatgcccccg tctaatctag cggtcatctc
    67201 tcctcccatt ccttccacca atttttttga caggtaaagc ccgattccgc tagattccgt
    67261 atttgtgcgg ctggtatttt cggtataaaa acgctggaag actttttcaa cagaggtttg
    67321 cgctcctggt ttgataggat tggccactgt taatcgaatg aatgaatcct cttttgaaaa
    67381 tgtcaccttt gcttgtccat ctgcataacg caataaattc tgtatgatat tttgcagcac
    67441 tcgcagcaac atgagcggat ctgctaatac agttgtattt atcgagtgtt cagcgaacgc
    67501 tacctcgata tttttctcag aaaattgttc ataaaaagag aaaaatactt cttccacctc
    67561 tttagaaaaa gaaagcgtat ggagatccat ttctttttgc ttcgtctcta ttcgagcaag
    67621 atcataaaac tgatccgtca tactgagtaa tcttgcaaca gattgtttga tgatcgttaa
    67681 atacttctcc cgtttctccg tatcctctac ctgttccagt aattgtacat aaccgttaat
    67741 agcagtcaaa ggagttctga gatcatgaga aaggccgacg atcgatagtc tgatgttttc
    67801 ttccatttct tgaaatgctt gtcctttttg ttcattttca tccacccatg tattcagtgc
    67861 atctactagg tccattagat tcttttctcg aaattcgact gaaagacgac caccatattc
    67921 ttgtcgttca gaaagagtgg cgattttctt agttaatctc ttgatttccc tttgcaggaa
    67981 gaaaataaaa cttcccataa agataacaac gagaagcaac agccacttaa tcaaatctaa
    68041 accccactcc ccacaccgta tgaatataca cagcatgtgc ctttgctagt ttccctcgaa
    68101 gattggaaat atgcatattc actgttttct cactatcaaa atatggttct tgccaaactg
    68161 tttcataaag atttgctcgc gaaaatactt ttttcggatg ttctaaaaaa agcttcagca
    68221 gatcgaattc tcttcctgtc aaatggacag ccacaccatt cacatttaca tccctcgact
    68281 ctttgtccag taagatttcc ttgtaataga tgcgttgcga cagatctttt acttggacag
    68341 aagtctgatg acgaagttgg atgccgattc gtaacaacag ttcttcgata tcaaatggtt
    68401 tcgtcacata gtcatccgct cctgctgcca acaaggaaac tttatctctt tgatcgcttt
    68461 ttgctgaaag aacgatgatc ggaacattcg atgtctgtcg gatttctgct aacaatgctt
    68521 cacctgaaag ccctggaagc atgagatcta gaaggatcaa atcgacagga tatgtgctta
    68581 acaataattt tccttccgta cctgaataag catcaagaag tttgtatctc tgttcaagaa
    68641 cctcctccag taaagaatga acagcttcat cgtcttcgat aatcaaaata gtttccagca
    68701 ggaacaccta cttaatgtca gatttttgga aaataaacat tcctagagct gatgatacca
    68761 cgattgttac tagactgacc agaatcattt tcggtgcttg cgaataagtt gcttgttgcg
    68821 caaagtccgt atacatgagc cacgtttccg taaaccactc cgttagaaat tccaagcctt
    68881 tgatttttgc gaaaacaccg ggaacgaagg ccgttcccat gatataaaga aaagaaagaa
    68941 gcaaactgac actggtactt ctagtgatga atgtcaaagc cactggaaca gataatgtcg
    69001 ctaatatcag cagaagcaat acaggaaata cttttagaac ataatttcca tagtttttga
    69061 ttccctcaac ttcaccaaat ccgaaagcaa gtgtgtaagc aatcatggct agccccgtaa
    69121 tcaaaaccac gccaagtgtt gtgatcaaaa gcgtaacgag aagtttcgac acataataag
    69181 tcattcgatt ccgtcctaaa gataacgtat tgcgaatcgt accgttttga aattcttccc
    69241 caatataaaa gcacgcaaat gctgcgaaag ccagaagaat ccatgcagcc attttttcca
    69301 ccattaaaat ccctgttgca ccgttgatga ctgtatccgt tgcttggttt aattcattgc
    69361 cgtattttgt atgcatatac cattcgttcc aagaataaaa aagcggaagt acgaccatca
    69421 gtcctagtga gacccacatt ttacggctct tccatacttt tattttttca gcagttaata
    69481 gattaaacat gtggattgcc tccagttaat tgtaagaaat aatcttccag tttttgccca
    69541 actaggtgga taccatccac aggaactttt gcctctacca atgcttgatt gatggctgct
    69601 acttggtcaa ttccttcaaa aagctggata acacggctag attggacaaa ataatcccta
    69661 taaccaagag agtcgagaac cgttactgct tgttccgtcg ccgaagtgtc aatttttata
    69721 aattgacgag attcttgtgc caattcttct ttcgataatt ctttgatcaa gtgtccttca
    69781 tgcaaaatac cgtagtgagt ggcgatctgt gacaattcat ctagcaagtg gctagaaagc
    69841 aagacggtga tgccccgttc ttttaccaaa cgttggatga tttctcgcat ttctgccatc
    69901 cctgctggat ccatcccatt cgtcggttca tccaaaatca aaaattctgg attcgtgatc
    69961 agtgcatttg caatagctaa acgctggcgc atacctaaag agaaattctt tgctttcttt
    70021 ttccctgtat tttccaatcg catcattttc agcaggtctt cgatttctct atccgacaca
    70081 ccgccgttcg ctgcttggat acgtaggtta tctcttgcag ttaattctgg ataaagagca
    70141 ggggtttcaa tcgattgacc catacgtcgt cttgctgcct gcaaatccgt cgttccaaat
    70201 aattcgatcg aaccttcatc aatcgagatc aaacccataa tagttctcat aaaggtagac
    70261 ttacccgctc cattctcccc aatcaaacca tagatcattc cacgtttgat ttcgatcgat
    70321 actttatcta atgctttggc agcaccgtat tttttggtta taccagttgc tttcaagacc
    70381 gtttcatttc caaaatccat acttatcctt ctttcttatt gataagtgaa gtatagttga
    70441 cgggtataaa gaaagcagcc agaaatgtat aaagaaagtg taaattttcc aattgaattt
    70501 caagaaaaat cagactgtct cgcagacgtg gttgagttgt ctgccaatca aagagcgcac
    70561 caaacagtgc taatccaagt ggactggcca ccatggtaat cgttgttatc gttgacatca
    70621 gacgtccttg tatatgcgtt ggaacttctc gctgaagcca gaccatataa aaagcaaaag
    70681 aaaacattaa tccttaaaaa cggacttatg aaaaataata catgccgttt gggatttaca
    70741 attagctacc aaataagagg ttatgacaaa agacttttca caatcccttc ttccgaataa
    70801 acggtgttct cctgccaact cctcggtcac aagtcacaat atttatcaaa catgagaagc
    70861 aatttttgta aattccttct tatttcttga agctgaccac ttctgtcaca acctcagaag
    70921 cggataaata atattgtttg atgatacttt atctttttcc cgtttgttta tagatcgaat
    70981 gatattatag accaagaatc ctacctatta acatagctaa aaacacaaaa aaggcacttt
    71041 ccaaattgtg gaaagtgcca gaaaagttag gattaaggta actgcgctca gcattgcttc
    71101 gcccagtacg attctcgtaa ctcgtgaact cgaacgataa tcgcaattaa cgttttgaga
    71161 actgtgaagc tttacgggct ttcttaagac ctggttaaac aaaactctat tttattgcat
    71221 tttacaggaa tgtatttcat gcgaaattaa taagtctttg tttatagagt tttactaggg
    71281 tataaaaagt tgtatgttat cattacctca aaacattacc tcagcttggc gagttggttg
    71341 attgaagaat aaatcattta tctagatatc tcaataaaaa atgatttcta agaaacttgt
    71401 attttcgtgt tattattttt ttgccctatc aaaatttcta attcttctag cgtaatatga
    71461 ttatgacaca taatcgattc aattacttca atacctattt ttttcgagaa agatcccttt
    71521 tgttcactca caaaaatact ttcagaagac atatataagg aacgaagttt tggaattagt
    71581 atatcgtaca aatagaccac cataaaatcg tccttgcaac cattctcaaa aagaattaaa
    71641 tttgctgatt gtgttacata tatcactgaa ttacattcat ggtcaattcc aaaaacaatg
    71701 tctacttcat tttcttttct aattcgcgca gttacatttt tcaaactttc accattactt
    71761 ataaatgctt tagttactgt aagctctgat gtttgttcag atattccttt tataatattt
    71821 tgttcatcag ccacattccc cataaatccg ccgattcctt ttaagtaata attctcacct
    71881 aagagtcgct tgcattcact gaattgataa aaaaaccagt taaaaaaatc ttctggaaaa
    71941 ataaattctg atcgaacttt atttatattt ttagctccta ttaattttat aactcgatta
    72001 atgttcactt gctgcgatga acatataact gaataaattg agttgtttaa ttcaaaaaaa
    72061 caactttaac atatgcatca ttaattcgtt attttttagg tagatattga tcattgttat
    72121 ctctcttttt ttgcttccca tactccaact tagaaattgc cgttataaaa tttattttaa
    72181 aggtgacttt ttcccctgaa gtatcggtag taggaatact taatacctca gcttctgagg
    72241 aggtatccca attatagtta tactttgcat catcaccata aagaacaatt ccattttttt
    72301 tatcttgtgc cgttagcttt actggttcgc ttacttttct tgttaatatc ttggacttta
    72361 catcatcgat attgcttatt ttatcaagct taaataattt acaaattaat ttcgtactag
    72421 tttttatatt tga
//
LOCUS       DAIGTA010000006        68492 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.006, whole genome shotgun sequence.
ACCESSION   DAIGTA010000006 DAIGTA010000000
VERSION     DAIGTA010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.006"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            5..304
                     /locus_tag="NOB43_000394"
     CDS             5..304
                     /locus_tag="NOB43_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0981291.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            377..1738
                     /locus_tag="NOB43_000395"
     CDS             377..1738
                     /locus_tag="NOB43_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI0981292.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1760..2020
                     /locus_tag="NOB43_000396"
     CDS             1760..2020
                     /locus_tag="NOB43_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981293.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2034..2786
                     /locus_tag="NOB43_000397"
     CDS             2034..2786
                     /locus_tag="NOB43_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCI0981294.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2880..3485)
                     /locus_tag="NOB43_000398"
     CDS             complement(2880..3485)
                     /locus_tag="NOB43_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0981295.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3538..4512)
                     /locus_tag="NOB43_000399"
     CDS             complement(3538..4512)
                     /locus_tag="NOB43_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HCI0981296.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4890..5609)
                     /locus_tag="NOB43_000400"
     CDS             complement(4890..5609)
                     /locus_tag="NOB43_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0981297.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5736..7007)
                     /gene="celB"
                     /locus_tag="NOB43_000401"
     CDS             complement(5736..7007)
                     /gene="celB"
                     /locus_tag="NOB43_000401"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI0981298.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7160..8557
                     /locus_tag="NOB43_000402"
     CDS             7160..8557
                     /locus_tag="NOB43_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0981299.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8638..9078
                     /locus_tag="NOB43_000403"
     CDS             8638..9078
                     /locus_tag="NOB43_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0981300.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9226..9552
                     /locus_tag="NOB43_000404"
     CDS             9226..9552
                     /locus_tag="NOB43_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0981301.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9553..10302
                     /locus_tag="NOB43_000405"
     CDS             9553..10302
                     /locus_tag="NOB43_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981302.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10382..10837)
                     /locus_tag="NOB43_000406"
     CDS             complement(10382..10837)
                     /locus_tag="NOB43_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI0981303.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11264..11539)
                     /locus_tag="NOB43_000407"
     CDS             complement(11264..11539)
                     /locus_tag="NOB43_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981304.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11833..12648
                     /gene="thiD"
                     /locus_tag="NOB43_000408"
     CDS             11833..12648
                     /gene="thiD"
                     /locus_tag="NOB43_000408"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCI0981305.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12977..14428)
                     /gene="cls"
                     /locus_tag="NOB43_000409"
     CDS             complement(12977..14428)
                     /gene="cls"
                     /locus_tag="NOB43_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI0981306.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14769..17435
                     /locus_tag="NOB43_000410"
     CDS             14769..17435
                     /locus_tag="NOB43_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0981307.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17799..18551
                     /locus_tag="NOB43_000411"
     CDS             17799..18551
                     /locus_tag="NOB43_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0981308.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18573..19727)
                     /locus_tag="NOB43_000412"
     CDS             complement(18573..19727)
                     /locus_tag="NOB43_000412"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HCI0981309.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19912..22353
                     /locus_tag="NOB43_000413"
     CDS             19912..22353
                     /locus_tag="NOB43_000413"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HCI0981310.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22683..23387)
                     /locus_tag="NOB43_000414"
     CDS             complement(22683..23387)
                     /locus_tag="NOB43_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981311.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23574..23819)
                     /locus_tag="NOB43_000415"
     CDS             complement(23574..23819)
                     /locus_tag="NOB43_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981312.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23836..24687)
                     /locus_tag="NOB43_000416"
     CDS             complement(23836..24687)
                     /locus_tag="NOB43_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0981313.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24853..25857
                     /locus_tag="NOB43_000417"
     CDS             24853..25857
                     /locus_tag="NOB43_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCI0981314.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26098..26454)
                     /locus_tag="NOB43_000418"
     CDS             complement(26098..26454)
                     /locus_tag="NOB43_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0981315.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26822..28009
                     /gene="tuf"
                     /locus_tag="NOB43_000419"
     CDS             26822..28009
                     /gene="tuf"
                     /locus_tag="NOB43_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI0981316.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28197..30788)
                     /gene="mprF"
                     /locus_tag="NOB43_000420"
     CDS             complement(28197..30788)
                     /gene="mprF"
                     /locus_tag="NOB43_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI0981317.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30814..31575)
                     /locus_tag="NOB43_000421"
     CDS             complement(30814..31575)
                     /locus_tag="NOB43_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0981318.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31742..32374
                     /locus_tag="NOB43_000422"
     CDS             31742..32374
                     /locus_tag="NOB43_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HCI0981319.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            32433..33293
                     /locus_tag="NOB43_000423"
     CDS             32433..33293
                     /locus_tag="NOB43_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HCI0981320.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33478..35793
                     /locus_tag="NOB43_000424"
     CDS             33478..35793
                     /locus_tag="NOB43_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0981321.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35975..37816
                     /locus_tag="NOB43_000425"
     CDS             35975..37816
                     /locus_tag="NOB43_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCI0981322.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37840..38949
                     /gene="rpoD"
                     /locus_tag="NOB43_000426"
     CDS             37840..38949
                     /gene="rpoD"
                     /locus_tag="NOB43_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCI0981323.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39169..41268
                     /locus_tag="NOB43_000427"
     CDS             39169..41268
                     /locus_tag="NOB43_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI0981324.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            41464..42327
                     /locus_tag="NOB43_000428"
     CDS             41464..42327
                     /locus_tag="NOB43_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI0981325.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            42432..42905
                     /locus_tag="NOB43_000429"
     CDS             42432..42905
                     /locus_tag="NOB43_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0981326.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            43001..43888
                     /gene="xerD"
                     /locus_tag="NOB43_000430"
     CDS             43001..43888
                     /gene="xerD"
                     /locus_tag="NOB43_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCI0981327.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            43907..44278
                     /locus_tag="NOB43_000431"
     CDS             43907..44278
                     /locus_tag="NOB43_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI0981328.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            44248..45045
                     /locus_tag="NOB43_000432"
     CDS             44248..45045
                     /locus_tag="NOB43_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HCI0981329.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            45029..45598
                     /gene="scpB"
                     /locus_tag="NOB43_000433"
     CDS             45029..45598
                     /gene="scpB"
                     /locus_tag="NOB43_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HCI0981330.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            45604..46320
                     /locus_tag="NOB43_000434"
     CDS             45604..46320
                     /locus_tag="NOB43_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI0981331.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      46402..46527
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            46650..47261
                     /locus_tag="NOB43_000435"
     CDS             46650..47261
                     /locus_tag="NOB43_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0981332.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            47639..49162
                     /locus_tag="NOB43_000436"
     CDS             47639..49162
                     /locus_tag="NOB43_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCI0981333.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            49399..50739
                     /locus_tag="NOB43_000437"
     CDS             49399..50739
                     /locus_tag="NOB43_000437"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HCI0981334.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            50892..51629
                     /locus_tag="NOB43_000438"
     CDS             50892..51629
                     /locus_tag="NOB43_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HCI0981335.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51794..52015)
                     /locus_tag="NOB43_000439"
     CDS             complement(51794..52015)
                     /locus_tag="NOB43_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCI0981336.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            52046..53077
                     /locus_tag="NOB43_000440"
     CDS             52046..53077
                     /locus_tag="NOB43_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0981337.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            53064..54467
                     /locus_tag="NOB43_000441"
     CDS             53064..54467
                     /locus_tag="NOB43_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCI0981338.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            54533..55168
                     /locus_tag="NOB43_000442"
     CDS             54533..55168
                     /locus_tag="NOB43_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0981339.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            55217..55897
                     /locus_tag="NOB43_000443"
     CDS             55217..55897
                     /locus_tag="NOB43_000443"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCI0981340.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            56032..57261
                     /gene="rpsA"
                     /locus_tag="NOB43_000444"
     CDS             56032..57261
                     /gene="rpsA"
                     /locus_tag="NOB43_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCI0981341.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            57443..58753
                     /gene="der"
                     /locus_tag="NOB43_000445"
     CDS             57443..58753
                     /gene="der"
                     /locus_tag="NOB43_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCI0981342.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            58996..59271
                     /locus_tag="NOB43_000446"
     CDS             58996..59271
                     /locus_tag="NOB43_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HCI0981343.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            59506..60552
                     /locus_tag="NOB43_000447"
     CDS             59506..60552
                     /locus_tag="NOB43_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981344.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            60554..61813
                     /locus_tag="NOB43_000448"
     CDS             60554..61813
                     /locus_tag="NOB43_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI0981345.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            61819..62400
                     /locus_tag="NOB43_000449"
     CDS             61819..62400
                     /locus_tag="NOB43_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HCI0981346.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(62482..63357)
                     /locus_tag="NOB43_000450"
     CDS             complement(62482..63357)
                     /locus_tag="NOB43_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0981347.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            63505..63837
                     /locus_tag="NOB43_000451"
     CDS             63505..63837
                     /locus_tag="NOB43_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI0981348.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            63949..65157
                     /locus_tag="NOB43_000452"
     CDS             63949..65157
                     /locus_tag="NOB43_000452"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HCI0981349.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            65311..65766
                     /locus_tag="NOB43_000453"
     CDS             65311..65766
                     /locus_tag="NOB43_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981350.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            66128..66403
                     /locus_tag="NOB43_000454"
     CDS             66128..66403
                     /locus_tag="NOB43_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981351.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            66416..>68492
                     /locus_tag="NOB43_000455"
     CDS             66416..>68492
                     /locus_tag="NOB43_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCI0981352.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
BASE COUNT        22618 a        11818 c        14352 g        19704 t
ORIGIN      
        1 aaaaatgaaa aatcggttaa ttgtcgcatg tggaagtgga gtagcaacga gtcagacaat
       61 cgctagtaag atccaaagta tgttagaaga tgacggcatc gcatttcctg tagaagcagt
      121 tgattacaaa tcgattcaaa atgagcttct aactgctgga atctatgtgt atgtcgcaca
      181 acctgatgag gaagtacttg aacaagcaaa agatttgggt attgaagtat ttccaggaat
      241 tccattttta actggaatgg gtgtagaacc tatttatgac agtatcaaag agttagtaca
      301 gtaaaggagg attgttggat aaaaaagttg gttcatagtt ttatttacta tatttagaaa
      361 gaaagaaggt ttatttatgg aagttttcca aaccattatc aattatgttt tgaacttagg
      421 atcagccatt tttgttcccc tgattatttt gatacttgga ttgttggcag ggatgaaatt
      481 aaaaaaagca ttcatgtctg ctttgacttt agggattgct tttagcggaa tgtctatggt
      541 cattggctat atgtctaacg cagtaagtcc agcatcagaa gcattggcta aaaatacggg
      601 aatcagtttg cctgcacttg atcttgggtg gacaggtgca gcaagcatca catggtcgtg
      661 gagttatgct tttatatttt ttgcagtaac gattggggtc aattttgtac tgttactttt
      721 taattggacg aagacgttaa atgttgatat gtggaatgtt tgggggaaag ctttaactgc
      781 ttatttagtt tattatgttt ccggtagttt ggctgcaggc tttcttactg caatggtcca
      841 agttatattg gaattaaagc ttggtgatat gtttcaaaaa catatacaag atctcacagg
      901 gattccatta gtaacagtga ctcattttat gacatctgcc gctgtcttgt tgctgccttt
      961 caatatgatc atggataaaa ttcctgcttt aaataaacga gcggatacga atgcattgaa
     1021 gaagaaaatt gggatcttct ctgaaaactc tgtaatggga ttcattattg gattggggct
     1081 tggctttgct gctgcgtatg gcgtttcagg ttctcttaat ctagcgatcc aaacagctac
     1141 agcattaagt ttgtttccta tgatctctaa aatgttcatg caatctttgt ctcctctagc
     1201 agacgctatg tcagaattta tgaaaaagcg gtttaaggat cgtgaagtat atatcggatt
     1261 ggactggccg atattagctg gtcgttcaga aatttgggtt actgctattt tacttgttcc
     1321 tgtgtttatt ggttatgcca ttattttgcc aggaaaccaa gtattgccat tagcagggat
     1381 tatcaactat tcgattgcgg tcggcggatt acttttaaca ggaggaaact tggctcgtat
     1441 gctgatcttg ggaatcatca ctatgcctat ttatttgtac ggggccactt accttgcgcc
     1501 aatactcagt gatttagcag aaaaaagcgg agcagtcgag ggaatcaaga aaggacagtt
     1561 gatcacatgg tcatccatag aagggccgga gttcagggtt ttatttgcgg aggcatttaa
     1621 taggaatatt ctcgctattg taggatgcgt gatttttcta ggactgtttg ttctacttta
     1681 taaatatatg ataaaagcga aagtaccgag tgaacgttat gctgaactac aaaaatagca
     1741 ttgaaatggt gggaaagtaa tgaaaagaga agagacagat aaaataaaat ggacagtcgc
     1801 tctttgtggt acacttctgc tatttctata tggactcttt actcagaata tcatcatcaa
     1861 tctattggtc atttttttcg cactagtgat ctataaatat ggaaatcacg ttttattcag
     1921 agagtacgat gaaaaaagaa aacggaaaat agaagaatca atgaaaataa aagaagctac
     1981 caaagaaata ttgagagaaa aaagttttat aaaaagataa tggaggggtc attatgtcag
     2041 atggacgtat gttatttgag agagaacgac aggacatggc acgtatcgta agagtgattt
     2101 tcgaaaggaa aaacacaaat gtcgcaggag ggaatttttc ctttaaaacc actgatgatc
     2161 aagggaaaga ctacatcatc atgacgccga ccatgatgtc agaagcctat ctaggagaga
     2221 tttctcctgc acaggttcta gtagtagaac caagaacgcg tagaatcgtt gacggagtcg
     2281 gtcatttaac tcgtgaaatc aatatgcatg aagcgatgta tgagactaat ccagctatca
     2341 aagctgtcct acatgctcat gcgcctaatg caatgttctg ggcgactact gggttgccta
     2401 tgcctaattt gacagaagcc acagctaaag taaaagagat tcctgtcatg gactttgagc
     2461 ctaattgctc tgaagaactt gctgaattga caagcgacta tgtaaaaaaa cagcatctcg
     2521 aattaccgca tatgttgctg ctcaactctc atggcgtatt gatcaacaca ggtggagaat
     2581 caggaatcga agctatccat aaagcactgc aaatccttga tacagttgaa tggaatgcag
     2641 aaattgccta caagcagacg atttttcaag cattagggat tactgacggt ttttattcaa
     2701 aaggtgagaa aatcggggga ttggaagagt tgaaacataa aacggctatt tataataaat
     2761 ctgttattgc agctggtgga gactaaccta tctgacacaa aaaactacga ctttcacaaa
     2821 atctgatcca gatcgatatc tgcttcaggt tgtattatgt aagtcgtagt tcttttcttt
     2881 tatttagtta agaggtggtc tgtccattcc ctcgcttgct tgatttcgtc catcgtcaac
     2941 tgatgacctg ttacagttag ctgaatagtc acatttgctt ggcgtgtttc gaattgatcg
     3001 gccaattctt taaaggaagc aggggaaacg attggatcgt tatcaccata agaaatccag
     3061 acggttttat cctctaatgt ggaacggctt tgatgaacac ctagagacat cggatggaaa
     3121 aacaaccctt tatttagctc ggtctcacgc tccaataata aatgagcagc gatgtttgcg
     3181 ccatttgaat agccgacaag cagccagtca cttaacggta tcagttcttt ttcgctgatt
     3241 tctttgattt tttcatggag tttatctgtt tctttttcca aactgtccag gtcgaattga
     3301 ttcaatccat tacgcttgaa aaaacgattc atcccatctt cttggaccgt gccacgaaaa
     3361 gaaagcaatg tactgtttgg tgcaagaaag tgagcgatat ccagtaaaga atgttcatcg
     3421 ccacctgtgc catgaagtaa gatcaaatgc ttgccacttg ttcctttttc aaaaatgtag
     3481 gtcattttgt tccctctttt ctgtttctat agatgcaaat gaagtagcat gaagagatta
     3541 ttcacgtttt ttatttgcat cacttgtatc gaaaggacgg acataagctt caatggcttc
     3601 acgacgttct tctaagaatg gaggaagaga tagtttttct cctgctgatt ctgctggttc
     3661 atcttcaagg aatccaggac catcagttgc taattcaaac agtacgtgat gagcggctag
     3721 gaagtactca gattggaaat agaaacgatc gacgaaacca gaatttggca attcaatctt
     3781 attgattact tgaatccagt attccaatgc ttctttgtct gctacacgca atgctaagtg
     3841 atggatattt ccaaatcctt cgattgcttt tggcaagtct gtccgatgtt caataatgat
     3901 gcttgcacca tttccccctt caccgatttc aaataagtag aaatctcctg aatggtctgt
     3961 ttctttgaat cctaagattt tttcaagaat caagcggata tgctctaatt gactgacacg
     4021 gacaaagaca ggtccaagtc ctgtgatcgc aaactctgtc ggtacattgc tgtttttcca
     4081 aggaatgcca gctgctacac cttgattgtt ttcgtcagag atcaattgat aatactgatt
     4141 atcgaaatct tcaaattcga tatatttttt gccgaaacgt tcattgattg ctgaatgagt
     4201 aacgtcatat ttttcaaaac gttccaacca aaagtctaat gctgcgtcac ttggcacacg
     4261 gaaagaagca cgagagatcg tatctgttcc tttttttcct tttggctgat ttggaaaatc
     4321 aaagaaagtc atatctgttc ctggcgcacc agtatcgtct gtaaagtaaa gatggtaagt
     4381 ttcgatgtca tcttggttaa ctgttttttt gattaagcgc attcctaaaa tatctgtaaa
     4441 aaagcggtag atttttgtag cgctagatgt cattgctgtg acgtggtgaa ttcctctgat
     4501 ttgtgtatcc atgataaatt tcctcctgtt aacttacaaa aagtaagtag ttgatttaga
     4561 catagtatag agggtgcatc tctattttgc aattaatttg tcttctaaag tatcaggaag
     4621 gaatcaagaa tggaaaagag gagggacgga tcaataaaat aaaaagactt acgactagct
     4681 gtatcgattt caaaaaaact agctttaaaa agctaacttt agaatcatta cgggtggtca
     4741 taagtctttt tatgctgagt tattttttca tttttgagct aatgcttagg atagaataga
     4801 atgttgattt cacgatctct tcttgttact tgaaactgct taccactgtc acgatctctt
     4861 ggtaaacggc tttttcacaa cctctttggt taagttgaac gcacatccag cacagaatag
     4921 ttccgaacat caaatcggtt tcggctggaa gaatattcaa tcggctgtcc atctttgaga
     4981 tagacgactt gctgaacttc cagtacagga tcgttttctg cacagttcaa atattgctga
     5041 tcatattcat cacttttatc tgcagaaata gcacgataag cccctgcaaa atggacattc
     5101 aattcttgat gaagatgatc atagatagag gctaacaaat gttctttttt taaacccggc
     5161 acaagatgga ctggcataaa ggtatgctct aaaacatatg gctcgccatc taagatcctt
     5221 aaccggtgaa tattgtagac aggttgctcg gcatcgatca tcaatcgttc ttggatatat
     5281 tgattaggga attcaacatc aaaatgaatg atttgactct tcaaagaacg atgtctgcgt
     5341 ttcatttgga gactcaaacc ttcatactcg ttagcgggcg atgtgtcttt ttgcataaat
     5401 ggatgattca agattttcgt tcctgatcct cgctgcgaat agacaagtcc ttccattgct
     5461 aagatattga tggctttttt gattgtcatc cggctcgcac caaattcttt taccaagtcg
     5521 acttgattag gcaaaaaact atcgagagga tactcttttg aacggatacg ttctcttaaa
     5581 atatttgcga tttcttcgta ttttggcacg ttattcacct cttctagagt ataacgaaag
     5641 attatgcttc cgacaactcg aagtagcatc tggaacattg tttattcgaa aaaagaggtc
     5701 atgacaagtt tttgtcacaa ccccttaatg atctattaag caatatctaa atctggttgt
     5761 ttatctagta ctttcaggaa tgggtaccag ataaaggcaa cgatgacaaa gtcgatgact
     5821 tgcagcatac caccaagcca tgaatttgtt gctaagacac cgcttgcaat gattggcaca
     5881 gtccatggaa cagagacgcc agttggtgca gggacaagtc cagcagccat taccaaataa
     5941 ttgaacgtcg ttacgattag aggtgccaca acccaaggaa taaggattgt tgcattcaat
     6001 acgatcggta gaccgaagat cgctggttca tttacattga aaataccagg tgctaaagct
     6061 aatcgtccaa catcacgata ctgtttcttt ttaagaacaa aggccatcaa taaaacgaca
     6121 gctaaagtca ttccagagcc accaatacca acagtgaagg tttccatgaa tggttttgtg
     6181 atgatgtgtg gtaattcttt tccatgttga taagcttcta agttatcaag catcagtgta
     6241 ttccaaatcg ggtccattac agagttgacg atgatttgtc cgtgaagtcc gaagaaccat
     6301 aagaattgga caaagaacaa agcaatcaat gttgcaggta aactacttcc caaaccagtt
     6361 aatggttttt ggatcacttc ataaacgacg tcatgtaagt tagcattgaa aataccagtc
     6421 atcacagcat tgattactaa gaaaatagtt agtgtcacta cagcagggat caaagcggca
     6481 aatgattttg ttactgcagg cggaactcca tcaggcattt tgatctgcca gccgcgtttc
     6541 gtgattctgc agtagatttc tccagccaag aaagcagcga tcattccaat gaacattcct
     6601 tttgcgccaa gacgatcaag tgaaagcaca ccagtcacat cttcaccgcc agcggttttc
     6661 attgcaaaag gcgtaagaat caagaagctg gcaaaagaca cggcaccacc gaaaatacct
     6721 tcaacgtcat aagattttga taaataatag ccgataccaa aagtaacaaa aaccgacatg
     6781 atgctcattg ttgcattttg cccattaccg aataaattcg ataaagttcc ctttgttgcg
     6841 tcactgaaaa aaggcaagtt attgataacg acaacgatcg aaccgaacat cgttaaaggg
     6901 aaggaaagca tgaaagcatc ccgcagcact gtaaggtaac gattttgccc taataaatta
     6961 gctaagggca tgattttctc agaaagcttg tccataaaac cgttcatttt tattcacctc
     7021 aaatttattt gcaatcgatt acatacaaag tataacgcca aaaattttaa atgtctagtc
     7081 attttcataa aaagtattga tttatttttt agggttcgtt atgattacgg tatcaagaaa
     7141 aaagagagga agtaaaaaaa tgaaaaccta cacattccca gaaaattttt ggtggggttc
     7201 tgctgctagc ggaccgcaaa cagaaggaag agtaagtgat gatggtaaag gagaaaatat
     7261 ttgggatcat tggtatgaat tagagcctga aaaattcttc gatcaagtag gacctgaaaa
     7321 aacttcgcaa gtttacacaa aatacaaaga agatgttcag ttaatgaaag aaactggcca
     7381 taacacattt cgtacatcta tccaatggag tcatttgatt ccagaaggga caggtgaaat
     7441 caatcaaaaa gctgtttctt tttatcgaga ttattttact gaattgctgg ataatggtat
     7501 tgaacctttt gtgaaccttt accatttcga tatgccacta ccactgcaag aaaaaggcgg
     7561 atggttatca agagaaacgg tcgacgctta tgtttcttat gcagcagcgt gctttgaact
     7621 gtttggagat ctggtcaaaa aatggtttac tcataatgaa ccaatcgtac ctgtagaagg
     7681 aggctacttg tatcaattcc actatccaaa tcatatcaat atgaaagaag cggtccaagt
     7741 aggctatcat gagaatctag caagcgcaaa ggtaatcaaa gcctaccatg aaggcggaca
     7801 tgatggtgag atcggaatca tcttgaatct gacaccaagc tatccgagag atgaaacgaa
     7861 cccagaagat gtaaaagcgg cgaagatcgc tgacgcattc ttcaaccgat cattccttga
     7921 ccctgcagtg aaaggagagt ttccacaaga gttgatcgaa attgtcaaag aattggctat
     7981 aatgccagag atccatgaag gagacctaga actcatccgt gaaaacacga ttgacctgct
     8041 aggaatcaat tactatcagc ctcgtcgaat caaagcaaaa gaaactccaa tcaatcacga
     8101 acatagcccc atgccagatg attattttga taattacgac atgcccaata aaaaaatgaa
     8161 tccatatcgt ggatgggaaa tttacgaaaa aggaatctat gatattttaa cgaatacaag
     8221 agaaaactat ggtaatatca aatgctatat ttctgaaaat gggatggggg tcgaaggaga
     8281 agaacgattt gttaacagcg aaggaattat tgaagatgat taccggatcg agtttgttac
     8341 ggatcatttg aaatacgtcc atcaagcaat ccaagaagga accaattgtg tgggttacca
     8401 catgtggaca tgtatggaca actggtcttg gacaaatgct tataagaatc gctatggctt
     8461 tatcgctgtt gatttggcac aagacggtaa acggacgatc aaaaaatcag gtcgctggtt
     8521 taaaacggtc tctgaaaaaa acggatttga tgcctgatat tttttgataa aacgttcaca
     8581 aaatgtttgt tctaacactg taatcgtgct acactaacag tgaaggaggc gtttacaatg
     8641 gtagatactt atcgtaatat tttagtagca attgatggtt ctgaaaaggc agaaaaagca
     8701 tttcttgagg caatcacgat tgccaaacga aatcaggcaa cgttgcacat cctgtatgtc
     8761 aatgaagtaa caggcaatta ctttggtgat tttgcatttg ttacaacaag ccttcaggaa
     8821 gaattggatg aggttgcgga aaaccagatg aaagaacatc gaaacttggc aattgaaaaa
     8881 ggcctgacag atatcgagac atatgttctt tacggttatc caaagacact gattgctaat
     8941 ttccatgaat cgaaagaacc aatcgatctg attgtcatgg gggcgacagg tctgaatgcg
     9001 gtagaacgtg cactagtagg ttccactact tcctatgtag tcaaccacgc atcatgtaac
     9061 gtcatggttg taaaataaat aaattaaggg aacagaaagc aaaaaagcat aacgcttctt
     9121 ttgctttctg ttccttttat ttttttgtaa aaaattactt tacctgatga agtaatcatg
     9181 ctattctaat tacaacgaca gatggagtaa tatggaggaa agaaaatgat ttcaagtgat
     9241 ggaatacgcg gatacaatga tgcgattatt ttatcgatcc ttaacaaaaa cgattcttat
     9301 ggatatgaaa tttctaaaac gattcgtgag aggacaaatg attcctatgt gatcaaagag
     9361 acaacacttt actccgtttt tgcccgttta gaaaagaatc aactgattgt ttcgtatcct
     9421 ggagaagtga ctcatggaaa aaagcggaca tattataaaa tcactgaaat agggcgtaat
     9481 cttttagaag aaaaaaagca agagtggctg acgacgaaag acgtagtcga tcaatttttg
     9541 gagggaaatt aaatggatac aatccgtaat tatttagaca gtctttttat cggagtacct
     9601 caaagtaccg agatagataa gctgaaaact gatttgttgg caaatatgga agaccattat
     9661 catgaattga tgggagaagg aaaaaatgaa caggaggcca tcggtacagt aatttcgaca
     9721 tttggttcaa tcgatgaatt attagaagaa ctagatgtcg aaaaaaaaca tcaagctgac
     9781 gagacggaaa caaacacagc ttctatttat ttaagcgaag cagaaaacta ctggaaagaa
     9841 tacagagcgg caagtctcca agtggcatca ggtgttctat tcattagctt atcttttgca
     9901 agttttcttt tcttttgttc agcaggatat gtgttcatgg gtatttcttg tctgattttc
     9961 ggtatagcat tagctgtcgg tttttttatt gcttctggta tgaaaatcac acgtttaaat
    10021 cactttttgc accatcggaa aatacctgaa aaagtattag cagaagcaaa agaaaaagaa
    10081 gaagagtatc agcgaagttt tggcttctca ctgattgcag gaattggatt atgtattttt
    10141 tcacttttcc cacttttggc ttctttaatg tggtatatgg atggtagtat cggtgcctct
    10201 atattttttg ttacggtagg aacgggtgtc ttcttgatca tttatggcag tctagtccgt
    10261 cattcttatc gtcaattcac tcaaagcgct tattactggt gaatgtattc agatttgtaa
    10321 aaatattcta tttatccggc gtagaaaaaa agactgtgac acgcttttgt cacagtcttt
    10381 tttatatata ataatttaaa aattcatcat ctaaatccgt agaattttct agattgctta
    10441 cccatgtaaa atcgttatag acagatttca gttgacttct gcgccattgt acagggataa
    10501 aaagacgcat gctatcttca ttgaatccga ctaataattt ctttccgtca gtaatgatgg
    10561 gacgttgtaa caaagtaaaa tgcgagacga tcagatcgac aagctctgag gtcgtacatt
    10621 ggtcgatttg gtctttcaaa tttttataat caatcgagcg tttagctaat agatcgtcaa
    10681 atccgttttc tgttaatgac aataaataaa atatctcttt ccttgttaaa ggctgtttag
    10741 gtgtgaaaat tcgttctctg taaggcattt gatggtcttt cagccagttt gccatcagat
    10801 ggtaactatg tgtgcgagaa gaatagatcg taagcataaa aaaactcctt aaatagtcca
    10861 ttaatttgtt agatctgttg agataaataa taggtaagga gctgtgcata agcattgatc
    10921 aaaacaaccc aaacatcatt agaaataact ttctaaagtc ttaaacttgc gacgagaaac
    10981 aactagacta atagaaaaaa tgtcttagcc atttggcttc ctgtttgttt ttttgcttat
    11041 gctgcagctc ctcgggaaag ggttctaaca atttgaagaa ggttgatgat tgatctagtt
    11101 taaattgtgt gaaatttgaa atctggtgtt tttactagat gaatcaccta acaactatga
    11161 ttataactta tagaacttct gttttgcatt cggttttgtt atagttgtta taaagtttta
    11221 ttttattaca gaacattttt aattaataaa gaacagttag aagttaaaat tgctgattca
    11281 catagagttt atgacttctt ggaaattctt tttcaatcag ttttttcatc tgtttatgaa
    11341 attctttttt ttcagtaaac ataaaggttt gggtatcgta accttcttca tgtaggaaat
    11401 agattattcc tttttctgtg ttttgcgtat aagcttttat actcctgtct tttttgaaag
    11461 aacagatcgt atagccatct atttggtctg gtagtcgttt gattttcttc aaaatgactt
    11521 ttttatcctc aagtttcatt tttttcacct gactttattt ttttcatatg gaaatcatag
    11581 cgcctttggt tatatgaaaa caagaaggat actgaaatat atataaatca aatagtggtt
    11641 atttattatt agaatagcga atacaaataa acgaccacta ttttctgatt tattgcaaat
    11701 gttttttcaa ataaatttga ttaccaagaa aaggtagtgg tatatttact gagggatact
    11761 ttgaaaaaca tatgatagaa acagtaacag tattatgaaa aatcttttta taaaaatgga
    11821 ggaatcgatt tgatggaaga tcagtatgta caagcaatga cgatcgcagg atcagatagc
    11881 gatggaagcg cagggatgca agcagatatg catacattct ttacaagaaa tgtttacggt
    11941 gtttctgtca tgaccgcatg tgttgcaggt aattcttacg gaatcggagc aagtgtgaca
    12001 ttgccaacag attttatcga caaagaattt gaactgattg cgaaggactt tcaaatacgt
    12061 gcagctaaaa caggtatgct agcagattca aagttgattg agacagttgt aaaaaattac
    12121 caaaaatatg attttggacc attagtcgtg gatcccgtaa tcgtaacgaa acatggaaat
    12181 cttttactag aagaatctgc tttgcaaagc ttgaaagaaa agcttgtccc tttggccgaa
    12241 gtactgacac ctaattttta tgaagcagaa aagctgactg gacggacatt agcagctgaa
    12301 gaagattttg tgcaagcagc aaaagaactg caagatatgg gtgcaaaaaa cgttatgatc
    12361 aaaggacatc atgctaaaaa tgcgcagcaa gaaacagtca atgactacgt attgttcgaa
    12421 tcaggaaaat cattttggtt aaatgcacca ttttatccta ccgaccggat caacggaact
    12481 ggcgattcgc tatctgcatg tattgcagct gagttagcga aaggaaaaac agttgaacaa
    12541 gcgatccgat tggcaaaaga ctatgtaaac cgtgcaattc gtgaagaaat aaatgtaggg
    12601 cacaaatatg gccccatcaa tcattgggca gctggtgaat tagagtaaaa gaaagaagtt
    12661 gtgaaaaagt tgccctgcat caagtaataa gaacagccaa gtaaaaacag cttcttatgt
    12721 ttttaacttg gttggactta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    12781 ggtcgtgagc ctgccgtcca gctccgagtc acaaggaaca agttcaaaaa acagcttctc
    12841 atgtttgttg aatattgtga cttgtgaccg aggagttggc aggagaacac cgtttgttcg
    12901 gaagaaggga ctgtgacaag atttttgtca cagtcccttt aatcttagta tatttttctc
    12961 tacttgaata aaaaaattat aggattggag aaaataatcg agaaatttgt tgcttgaata
    13021 atagccagtt agacatttcc ttgactgttt cagttgtcat ggatgaacaa tgtgtctcat
    13081 cttctttgaa ctgagtagca agttcttcta aaaactcagg atcgtaaatg acagcacttg
    13141 tttcaaaatt caatcggtag ctacgaatat cttgatttgc tgaacctacc atgcagattt
    13201 catcatccat tatcaatgtt tttgcatgga ggaagccgtt ctcatagaca aggatttgta
    13261 cattttcctt gatcagctgc cgagcataat attgtgttgc tcgataaata aaaggatgat
    13321 ccggtttgtt gggaatcatg attttcacat ctacaccaga ggcagttgcg atttttaaag
    13381 cagcaatgac actttcatca ggaacaaggt aaggtgtctg tatccaaaca cgttttttag
    13441 cagaagtaat caatttgata aatgaaagct tgatttgttc cctttcgtta ttcggtccgc
    13501 ttgaaacaag ctggatggat gtatcagcaa gcttagattc atctcgatct gcttttttaa
    13561 agaaataatt caaatgatag ccgacctttt tttcttcagg taccgagacg ttccagtctg
    13621 ttaagaagcg aagctggagc aaagaagaag cggcaccgaa aatccgtata tgcgtatcgc
    13681 gccaatagcc gaattttttt gttgtattta catattgatt ggcaatattg aaaccaccgg
    13741 tataactaat ctttccatcg atcacaacga tttttcggtg atcatggtaa ttcaatcgga
    13801 aacgaagtaa tgccctttgt gaggtaacaa atgtatggac atgtccacca tttttgatta
    13861 gacgattgaa atcttttgct tttgtgccat gagagccaaa tgcatcatat aatattcgaa
    13921 cttccacgcc ttctgcggct ttttcttcta aaacatgtaa gacttgctgg ccgatattat
    13981 ctgtcacaaa tgcgtaatat tcgatatgga tcgaatgttt ggcttttttt agatcttgaa
    14041 gcagtgaatc caatttctct tgtccgtctg tgagaagagt gacagaattc attcttgtca
    14101 gcggcatacg atttaatgaa gagaagaagt caacaaattg ctgtttgtct ttatcgccca
    14161 tgtcaggatc gtaatgttca atggtatctc ctctaaaaga ctgaaagttt tctaattctt
    14221 tcaagtcact ttgtcggaga tagaattttt tcttatccgt taatccacgt ccgaaaaata
    14281 aatataatac aaagcccacc ccaggaaggg caaacaatac taagagccat gcccaaatgg
    14341 ctgctacatc tcggggtttg atcaaaatag ccaccaaagc aataagtgca tttaatagat
    14401 aaagggcggt tataatacta gataccacaa aaatgttcct ccttacatac aataacatta
    14461 gtatagcatg atagaagaaa gaagcctacc aaggtgaata tacttttcac tcctttcatg
    14521 aaaatgtagg taaatcgggc taaagtagtt gctttttgta ggttaataag gtaggatatt
    14581 agtacagttg aatatctcct taggggagta accggcaacg tttgttgcga taatatcaac
    14641 agtaagttaa ccaaatggtt ttctggtatt gtatgaaatg gtgagaccta agacaaatgc
    14701 gtatttgtct taggtctctt ttttttcaga caggactagg gccaagatca aaaaatgggg
    14761 gatgaaattt ggaaaacaag gaacaagcac aacaagcggt ctataaagaa acgatcgact
    14821 cgttgatgca gcaaacgcag agctcaaccg atggattgag caccacgcaa gcgaaggaaa
    14881 aattagaaag agatggcttg aaccagctaa aagaaaagcc gaagaagcca acttggaaat
    14941 tgttcttaga aactttcaaa gatgcaatgg ttatcgtatt gctgattgtc gcactgattc
    15001 agatggtcat gggtgactac atcgaattct tagttatttt tgcagtattg atgttgaatt
    15061 ctataatcag tgttgtccaa acaaaaaaag cagaaggttc tttagaagcg ttgaaaaacc
    15121 tttcagcgcc cgatgctcga gtgattcgtg atggtaagga aaaaacgatt ccggcaaacg
    15181 aacttgtggt aggagatatc gtgttgttag acgcaggcga ttatgtacct gctgatggac
    15241 gtttactaga tgcgggatca ttaaaagtag atgaaggtat gctgacagga gagtcgactt
    15301 ctgcagaaaa agaagtaacg gatatcacaa gtacggtacc aatcggagat cgtacaaata
    15361 tggtattcag tggaacgatc gtaacttacg gacgcggtaa attcttagtg acttcaactg
    15421 ggaataatac ggagatcgga caagttgctg gccttttgga atcaacaact gagcaagtca
    15481 ctccgttaca acgaggtctg gataaattca gtaaaaaact aagtttggct attttggcat
    15541 tgtctttatt gattttaggt atccaactgt ttcgtattta tcttggagaa ggtacaggag
    15601 atatgactgc agatatcgtc agcgcagtga tgtttgccgt agccgtagcc gtagctgcta
    15661 ttccagaagc attacagtct atcgtaacaa tcgtgttatc tttgggaacg aataaaatgg
    15721 caaaacgtca tgccattatt cggaagcttc cagcagttga aacacttggt tcgacaagta
    15781 tcatctgtac agataagact ggtacattga cacaaaacaa aatgacagtt gttgactact
    15841 ttttaggtaa tggcgatact ggggatttca caaatgaccc ttcaaaatgg acagctgacg
    15901 aacgtcgctt gatcgaaatc agtgttttag cgaatgatgc atcgatcagt gaagacggta
    15961 ctaaattggg cgaccctacg gaagtagcgt ttatcgactt tagtgaaaaa ttaaaccagc
    16021 cttatcagga aatccgaaac aactacccaa gacaagcaga acttcctttt gactcagatc
    16081 gaaaattaat gtctactgga cacacaattg ataacaaaaa ttacttgttt gttaaaggcg
    16141 gaccagatat cgtcttccaa cgcagtaaaa aagtattgct aaatggtgaa gtcgttccga
    16201 tgacggatga attgatgaaa aaattccaag agcaaaatga agctttttca acacgcgcat
    16261 tacgtgtact agcttttgct taccgtccac ttgataattt tgatttatca tttgaagatg
    16321 aagacgattt gatccttgtt ggtttgcttg ctatgatcga tcctccacgt gctgaagtga
    16381 ctcaggcggt aacagaagca agaagtgcag gaatcaaaac aatcatgatt actggtgacc
    16441 acaaaacaac agctgttgct atcgcaaaac aaatcgggat ttttgaagaa ggaaacctgg
    16501 ctttgaccgg gacggaacta gatgaattga cagaagatca actaaacgaa gttttagaaa
    16561 aagtcactgt ttatgcacgt gtttcacctg agaataaaat tcgtatcgtt cgtgcttggc
    16621 aaaataaagg tcatatctca gctatgacag gtgatggtgt aaatgacgca ccagcattga
    16681 aacaagcaga catcggaatt gctatgggaa cgggtacaga tgtggcaaaa gatgcagcag
    16741 cgatggtatt gacggatgat aactttgctt ctattgtcag cgcagtagaa gtaggacgta
    16801 atgtgtttga taatatcaag aaagctattt cttatctatt tgcaggaaat ttaggtgcga
    16861 tcattgcgat catctttgcc ttagttgctg actggtccaa tccatttaca gcattacaac
    16921 tgttgttcat caatttagtc aatgattcac tgccagcaat tgcattaggt acagaaaaag
    16981 ctgaacctgc tacgatgaac cgcccgccaa gagatccaaa ttcaggaatc tttacggaca
    17041 aaacattgat ttctgtaacg tatcgtggtg tgctgattgg gattgctgtt atctttgctc
    17101 aatggcttgg catgcagcat tcacctgaat tcggtgtagc catgtcattt tcaacattga
    17161 tttggtgtcg gacattgcaa acattcccag cacgttcaaa cacacaaaca gctatccaag
    17221 cagggttctt ctctaacaga agtgtcttac tagctgtagt tgtatgtagc gcgctttact
    17281 gcttaacaat gatcccagga ctgaaagaag tcttctctat cccatcagca tttggattga
    17341 cagaagtctt tacatgtatg ggaatcgcac ttgtgacaat tgttttgatg gaaatcacta
    17401 aattgatcat tgtacgagta caaggaaata aataaaacga atcaacgagg ttgtgagcct
    17461 gccgtttaat tctgagtcac aaggtgcaat ttcaacaaac agcttctcat gtttgttgaa
    17521 tattgtgact tgtgaccgaa gagttggcag gagaacaccg tttaaggaag aagttgtaaa
    17581 atcagcattt tgagctaata ctgagggtca tctgattgga cactgtttat tcggaaagag
    17641 ggactttgac acgactttgg tcacagtccc tttttttatt tatgatagac ggaaagccaa
    17701 tcattttatt attcatcaaa agagatagaa tagataaaag aggagaatga tttattccga
    17761 aaagtgaaaa catataacaa aaaattagag gaaatcaaat gaatgaaaaa gaatgggatg
    17821 aatttgctga agaatattat gaaatccagc aagaatcgca agtaactatt gctgaagatg
    17881 taaaaaatta tctgaaaacg gagaaagtcc tgcctgctga aacagcagca gacgttgctg
    17941 gaggatctgg cagatttctt tccttagcaa aagaaattaa tcgctatgat ttgatcgatt
    18001 tttcttcagg aatgctagaa aatgcaaaaa aagaagcaga aaaaaatgag ttgccaaatg
    18061 tttcctttat caaacagtcg ttagaagaat ttatccaatc aaatgagaca tatgaaatgg
    18121 tttttacagc agcaaatcca gcattggtac atcttattca attagaaaaa ttgatgaaaa
    18181 agtcaagcaa atggtgcgtg ataatcagag tagtggaatc aatcgatgat gttttttatc
    18241 ctatcgaaaa gcaactagga atgatagaag aagatcctaa tacatcgcca gttgtaatgg
    18301 atcaatttga aacatactta attgatgaag gattcaaagt gaagaaaaaa gattttactt
    18361 attttacaca ggaatcaatt actgaagaat tgatgaagct atactatgac gcgtacgcaa
    18421 aagatcctgt tgtgaccagg tacattcgca aactattcag tgaaaaacga gaaatcctta
    18481 gtacgactaa gctgacctat agactgctcc tttggtccgc agataaaaaa agaacctttc
    18541 acgactcgtg aagggttctt tttatgattt tattatattt tgtagtaacg aatatcattt
    18601 tcgatctttg taatcgaaaa aggtacatct gaagtatatt ctgcacattc tccgtgttca
    18661 ggaagcgtct cactgaaaat cgtttcatat tcgtcaacag tgatccgtgt tcgagaatct
    18721 agcatctctt gatgagattg tgcgaagaga tattcttgat agttttcttc cagataacct
    18781 gtaaaaaatt cacttactgc accagaaccg tagctgaata gaccgatgcg atctcctggc
    18841 tgtagtgatt tcgaattttc cagtagagaa gttagcccca ggtataatga accagtgtaa
    18901 agattaccga ttcgtcggct gtaacggatg ctttcttcat agcgagccat aagacgttcc
    18961 tgattttctt cgtctgtttg gtctaatacg ctttgcaatg ccttttttcc catcttagta
    19021 tacggaatat ggaaagcaat cgcctgataa tcttcgagtc ctcgacccga caattcttta
    19081 tgtcgattcc aaactttttg gaatgattcg atatacgtag aattagataa aggaccatca
    19141 acaacaggaa attcgctata atctggacgc cagaaatcat agatatcttc tgtcagaaat
    19201 acgctgtcgt cttcaatcga taaaatacgc gggttttgag tgatcatcat cgcaacagca
    19261 ccgacacctt gcgtcacttc accaccgctt gccaagccgt aacgagcaat atcacttgct
    19321 atgactagta cttttcgttc tggatgattt ttgacatatt ctttcgccat gtgcaaagct
    19381 gcggtgccac cgtagcaagc ctcttttact tcaaaagaac gagcaaaaga ttggattttc
    19441 agtaaatggt ggataattac cgcactcgct tttgaatgat caatcccgga ttctgttccg
    19501 acgatgacca tgtcgattag ctcacggtct ttttctgtta cgattttgct ggcagcattt
    19561 gctcctagtg taatgatgtc ttcatttgca cgattgactg ccatttggtc ttgaccaatc
    19621 cctatatggt attttgcagg atcatcccca cggctttctg ccaactctgt catatctaaa
    19681 tataaattag gaataaaaaa ggaaagacga tcaatcccta ttttcatttc aacacctctt
    19741 tacttatgat aaaaaactta ctttactaag gtatcataaa aagattaaaa gaaatataaa
    19801 aaagagaata tttaaggatt gttaaaattt aatcttagaa aaaaataact ggaacaagag
    19861 ctatttgttt ttacagcaaa gaatggtata tttttgtagg aggtggctta cttgaaagaa
    19921 gtcgttatga tagatgctgc aagaacgccg ataggaaagt atcgcggaag tttaagtcca
    19981 tttactgcag ttgaattagg cacacttgtg actaaaggat tattagataa aacaaaactg
    20041 aaaaaagata aaatcgatca agtaatattt ggaaatgtcc tgcaagctgg taatggtcaa
    20101 aatgttgcca gacagattgc tttgaacagc ggtctccctg tagatgtccc agcaatgacg
    20161 atcaatgaag tttgcggatc tggtatgaaa gcagtgatct tagcacgcca gctgatccaa
    20221 ttaggtgaag cagaacttgt gatagccggc ggaacagaga gtatgtctca agcacctatg
    20281 ctgaaacagt atcagtcaga aacaaatgaa tatggtgaac caatttccag tatggtcaac
    20341 gacggattga ctgacgcatt ttcaaatgca catatgggat taaccgcaga gaatgttgca
    20401 acacaatttt ctgtgagcag agaagagcag gatcgctatg ccttgtcgtc ccagttgaaa
    20461 gcagcacatg ctgtcgaagc cggtgtattt tctgaggaga tcatcccagt caagatttct
    20521 gatgaagacg tgttatctga ggatgaagca gttcgtggaa atagtacatt ggaaaaactg
    20581 ggcacgttac gtacagtatt ctcagaagaa ggaactgtaa cagcaggaaa tgcttccccg
    20641 ttgaatgacg gtgcctctgt ggtgatcctt gcatccaaag aatacgcaga aaataataat
    20701 ctgccttatt tagcaaccat caaagaagta gcggaggtcg gtattgaccc aagtatcatg
    20761 ggaatcgctc caatcaaagc cattcaaaaa ttgacagata gatcaggaat gaatttatca
    20821 acaatcgatc tttttgagat caatgaagca tttgcagctt cttctatcgt agttagccaa
    20881 gaactgcagt tagatgaaga aaaggtcaat atatatggag gagcaatcgc attaggccat
    20941 ccaattggtg caagcggtgc acgtatcttg actacattag cttacggatt gcttcgtgaa
    21001 cagaagagat acggtattgc ttcattatgt attggtggag gtttaggctt ggcagtcttg
    21061 ttagaagcga atatggagca aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt
    21121 acgccatctg aacggcgcag tcaattaata gaaaaaaatg tattgacaca agaaactgcg
    21181 ttgatttttc aggaacaaac actttctgaa gagctctccg atcacatgat cgaaaaccaa
    21241 gtgagtgaag tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa tggcaagaaa
    21301 aaatggattc cgatggcaac agaggaacca tctgtcattg cagctgcaag taatggtgca
    21361 aaaatctgtg gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt
    21421 ctatcaggaa aatcggagta tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag
    21481 ctgattcttt gtgcaaatga aagttatcct tcaatcgtga aacgcggggg cggtgttcaa
    21541 gatatctcta ctcgggaatt catggggagt ttccatgcat acttatctat tgatttttta
    21601 gtggatgtaa aagatgcaat gggcgctaac atgatcaact cgattcttga gagtgtggca
    21661 aacaagttac gggagtggtt ccctgaagaa gagattctat tcagtatttt aagtaatttt
    21721 gctacagaat cattggcttc tgcctgttgt gaaatcccat tcgaacgctt agggagaaac
    21781 aaagaaatcg gtgaacaaat tgccaaaaaa atccaacagg caggggaata tgcgaagctt
    21841 gacccttacc gtgcagcaac gcacaacaaa gggatcatga atggtataga agctgtagtg
    21901 gcagctacag gaaatgatac acgtgcggtt agcgcttcga tccacgccta cgcggcaaga
    21961 aatggattat accaaggatt aacagactgg cagatcaaag gggataaact agttggaaaa
    22021 ctaacggtgc ctttggctgt tgccacagta ggcggagctt ccaatatcct gccaaaagca
    22081 aaagcatctt tagctatgtt agatattgat tcagccaagg aactagcaca agtaattgct
    22141 gcagtagggt tagctcaaaa cctggctgct ttgcgtgcat tagttacaga aggaatccaa
    22201 aaaggccaca tgggacttca agctcgttca ttagcgatct caattggggc tattggtgag
    22261 gaaatcgagc aagttgcgaa aaaattacgt gaagcagaaa agatgaacca gcagacagct
    22321 atacaaatat tggaaaaaat ccgggaaaaa taaaaaagca atatctttag aagaataaag
    22381 caagatttac agttatttta tttactgcag atcttgcttt tttctctatc agaaaatatg
    22441 tttattatta gaatttttta tagttaaggt taggcatctt aagaaatcag gcaactccaa
    22501 gatatcttca ggtagaagag aagtcgccta acattgtagg atcataggtg atttgttgga
    22561 caggtcaagc tgatatttga gcctgatgtt agaaggaatt tctttttact tgctgtagaa
    22621 attattatat gactaaaaag gctgggattt taaatcccag ccttttatga caaatagaat
    22681 ttttatcgat cagtaatcgc tgtcgctgca aattgttcga tcaaaggaat caaagtcaat
    22741 ttgactttgt atttccgttc gagtgctttt tcgataacga actcattttc agtagtcata
    22801 gaaatagttg ctaatttacg aggttcatca gcattttttt cattaataac tacttcatgt
    22861 tcattttgtt ctgtgtaaaa tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa
    22921 cttaaagcgg cattcgtatc agttgagcgt gtattttcag ttgtgtccgc ttttggtttt
    22981 tccgtttttt cttctggcac actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc
    23041 gcagttggtt catcgttttt caatcgttga tcattccagt aagacacgat ttcaataaga
    23101 agattgtcac ggaatcgttc gaaaatcccg ttttctcctg aacgaattct ctttaataca
    23161 gtattgaagt tgtcatcgat tggcacgttg atccgtgtat cttcatttgt tttcccagct
    23221 aatccgatcg ttaagatttg acggtttttg ggatcaagca tgacttgtaa cggcaaacca
    23281 taacgtcgca agctctcttc ttctagagaa cggaataatt gtcctcttac accatccaat
    23341 gaaggacgga attgatttaa taatttttgt ttctgttttt tcttcatatg ttctctcctt
    23401 cgctcatacc ctttcgatta taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa
    23461 aacttgcgta tacgcaaatt acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga
    23521 aaaataaaaa atggaacgga ttatgtatat atacataatc cgttccattc tttctatttt
    23581 ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg ttcgtgccag
    23641 ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt
    23701 gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg
    23761 gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat tggatccata
    23821 aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc cgactacacc
    23881 atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa ataattcagt
    23941 attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag
    24001 cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat
    24061 ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga ggatcatatc
    24121 atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa ggaaaacttg
    24181 attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt ggggtaagaa
    24241 attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa atgctcgcca
    24301 tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg gccagtggat
    24361 caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa aagaagacat
    24421 cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata tctcttctct
    24481 aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt atccttgggc
    24541 agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa cagcgacatc
    24601 cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac catttgatag
    24661 acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg ttcaactata
    24721 agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga aatttttgtt
    24781 taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac taagacagaa
    24841 gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat tgacagagaa
    24901 actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata tattcgtgat
    24961 tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg acaactagca
    25021 gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt ggaagcaagt
    25081 gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc acctagtgca
    25141 gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt attgaaagtc
    25201 aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat cgacaaccgc
    25261 ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga agcattcgct
    25321 gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa
    25381 aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa
    25441 aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga gacagaagaa
    25501 tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga aaaaggtcgg
    25561 ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct
    25621 tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt aaaagaagta
    25681 caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa cgggatcgaa
    25741 ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt gaataatccg
    25801 gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg tttataaaaa
    25861 tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt gtcaagagaa
    25921 ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa gaacactttt
    25981 gtctcacgct ctaaacacgt ataaacggcg gaagcagaag caactccttc ttatttcttg
    26041 gagttaaacg cttctgtccc agcctctttt tatctaataa aattttaaga ccatttacta
    26101 attatcgatt ttttctgccg catttttagg cacttcagaa gcctttattt cttcccagct
    26161 taatacacct ttacgaggat tgactttgag tttaagatac gcattcatct ttaatggatg
    26221 ttctctttct tcgcgaagcg tcacctgttt tttttcacca tctttattat aagccgcttg
    26281 cttgtaggta taagtcgtga atttctctcc gttatctgct tgggtagctg acatttcgcc
    26341 attcgtcgtg atttttgtat aataagcttc gccgccgtaa aaataatgat aagctgcaaa
    26401 acttccgccg agaaatatgc ctaaaacgac aagtacgcca attaattttt tcatgtactt
    26461 cacctctttc cttattatta acgaaataga agatttcgtc tattgaaagt tgttggcaac
    26521 agctgaattt taaacttttc ctcattttgt tcttattgct tcaaaagaaa gttaaggact
    26581 atcttgaagt ttttctcaaa aaacacattt ttttatttat aaaaggtact tttttcgcgt
    26641 ataagacaga cgagtgctct tagttgactt tgaccaatat tgacgtataa taagcttagt
    26701 tcgaatctta caaaaagtaa gtcggacgta ttctttttga tttagtcaaa aaaagactat
    26761 aataaaaagg tgagagctga aatttttcag tgatctatat tatttaggag gtttgtaaat
    26821 tatggcaaaa gaacattatg acagaagtaa accacacgtt aacattggta cgattggaca
    26881 cgttgaccat gggaaaacta ctttaactgc tgcgatcact acagtattag gcaaaaaagg
    26941 cctagcaaat cctcaagact atgctagtat tgatgcagct ccagaagaac gtgaacgtgg
    27001 gattacgatc aataccgcac acgtagaata tgaaacagaa aaacgccact acgcgcatat
    27061 tgatgcacca ggacacgcgg actatgtgaa aaacatgatt acaggggcag cacaaatgga
    27121 tggtgcaatc ttagttgttt ctgcaactga cggtccgatg cctcaaacac gtgaacacat
    27181 tttattgtca cgccaagttg gtgtaaaata cctgattgtt ttcttgaaca aagttgattt
    27241 agtcgatgat gaagaattga tcgatttggt agaaatggaa gttcgcgagt tattgagcga
    27301 atatggtttc ccaggcgatg acactcctgt gatcaaaggt tccgcattaa aagcattgca
    27361 aggcgatcca gatgctgaag ctgctattat ggaattgatg gatacagtag atgaatatat
    27421 cccaacacca gaacgtgata cagataaacc attactattg ccagtggaag acgtcttctc
    27481 aattacaggt cgaggaactg ttgcctcagg tcgtattgat cgtggtgctg ttcgtgtcgg
    27541 tgatgaggta gagatcgtag ggatcaaacc tgaaacacaa aaagcagttg taacaggtgt
    27601 agaaatgttc cgtaaaacgt tagattacgg ggaagctggg gataacgtag gcgtgttgtt
    27661 acgggggatc caacgtgacg atatcgaacg tggacaagta cttgctaaac caggttccat
    27721 tactccacat acaaaattca aagcagaagt gtacgtgttg acaaaagaag aaggtggacg
    27781 tcatactcca ttcttcaaca actatcgtcc acagttctac ttccgcacaa ctgatgttac
    27841 aggaacaatc acattgccag aagatacaga aatggtcatg cctggtgaca acgtgacgat
    27901 tgatgttgac ttgatccatc caatcgctgt tgaaaacgga acgacattct caattcgtga
    27961 aggcggacgg acagtaggtt caggtatcgt tacagagatc gaagcataag aaacgcgact
    28021 cgaatatttt ggtaatgaaa aatgtttaaa ataaaagagc ggtccaaaca ggatttctgt
    28081 ttggaccgct ctttgttctt caattgtata agaagagatt gtagaagcat gaactttcgt
    28141 tttacttcag tctcttttat tcatcatgag agtgttcatc tatcggtatg cagtttttaa
    28201 tactttcttc gtatccattt tttcaaacca cttattctac cttgtgtctg ctcaactggc
    28261 gcattatcaa taatcagcaa agcaatcata acatatgcaa tccaactatc tctagaatat
    28321 agagtataac gtgagaccca gtttgtagcg tacttgcttt tatattctct taatccatgg
    28381 aaagaataaa aatgagaacc aaactcgtaa accaagtatg caatcctttc ctgtaaaaaa
    28441 ctctttctgg aagttccgac atttgaaaga ggggccatcc ctaaattgaa ccattggata
    28501 tgttcttctt tcatataggc aaacaaatgc aagaacaaga aatccatact gccagaaggt
    28561 gcttttttag aatcatatcg catcagatca atcgttccta ctttattgtt cgtgtaagta
    28621 ggcatgatcg ttgcaaaagc gacaatttct tcttgggtat ttttgacaac tgcaataggc
    28681 gctctttgta gataatcttc agagaaaaag cctaaagaaa accctttttc ctttcgtgaa
    28741 cccaaccaat tatcagagat atttttgaaa gtactcattt gctcagtaga aaatggtggt
    28801 tgtaagacat caaatgtaaa tccttctcgt tcgatccgat tcaagacagc acgagtgccc
    28861 ttcatttttt tccctgaagt tgtaaaacta ttcaggtcta cataagcttc ttcccccatc
    28921 ttaatgaaat cgtagccgaa ttcatgcaaa atcataacaa tctcttcgct tgtttcgtag
    28981 aaaactggta aatagcatag tcgatctgtt tcttcgataa aagcttcgat tgcttctgga
    29041 aaatcttctt tcttaccaga aggatcaccc attacaatac atttattatt gaagcaagcg
    29101 aattggagaa gaacagttgg ttcaccgtct ttttcatagg caaacatccg cttatctttt
    29161 aagaagatca attgactatc ggagtttcct ccataagttg taaggatctt cagggccttt
    29221 tcttcattaa aggcttcgcc aatctgtttc ttttctcctt gaaggaaatg aacaaataga
    29281 acgatcatga aactaacagc gatgatggcc aacaatcccg aaaaccaaat cttttcagaa
    29341 ggaaataaga aaaaggaaat aaaatggtga cgccgatgag ggaaatctgg cagattgtat
    29401 accccaataa cgatgtaaag caaggacagt gcaccaataa tgattccatc gatcgtacgc
    29461 cactcccatg aatagatcaa ttgttcccga aataattcgt ttttagaagc aagaatgatc
    29521 agaagcagaa tagacaagaa aaccaccggt gtgaaactaa aatcacttaa taaaacataa
    29581 agtaaagcta gaacaatcaa gaagattgta ggcaaatatg ctcgtttcac acgtgctgcg
    29641 atccctctgc ccataatgat taaaagaaat cccaatagta tactaggaaa ttggataata
    29701 aaatgaaatt tcaatgggtt caaactatga agccagcgaa actctgtaaa agcttgcggg
    29761 atagtggcag aaagtactag catgattcca gaaaagtata ataagacaac cacgatttta
    29821 tgcgcaattt ctgttgctaa ttgtttaggg ataccagaat aacgctgatc aaaagtggaa
    29881 ccgatatttt tgaagaaaaa gacgattcca atcaaaaacg gaatgatgta gtagaacagg
    29941 cgatagagca agatccacac aacgactatt tctcttggca caccaatagc ggacaacccg
    30001 ataatcatca ttacatcgaa actcccaatt tctcctggaa tcatagacac gattcctatc
    30061 actgaagcag caatgaataa tggaattgtt tgccacagat caatccggat ttccattaaa
    30121 taaccaacag aaaggaaact aaacaggaca ccggtccatt ccaacaatga aactagcaat
    30181 agctgtcctt gagttttaag tgaggtacca ccaaggaatc ctttcttttt gaaagtagta
    30241 aataaaaaga cgacaggaaa atatagaccg ccgccgatca accatatcca atattgcttc
    30301 aaaaaaggag caactggcgt gaagactaca agtaaaaaag aaagcagact gtaaatagaa
    30361 agtccagcca tcaaaaacaa gaaaactttc gataatgctt ggatcacgtt tctgctctct
    30421 ttcttttgtc catatagttc agagcgaagc cccacactaa caaacccgcc gaaaccggca
    30481 atattgttga tcgtattgat cagccagctt gtctcaaaca ggtaacgagg attctgcttt
    30541 tgttcaagca tccgattcaa aataatatca taaccaacca taggtaacac agagataaga
    30601 ccaatcaata gcattagtcc gcttttccat acaggtatag tggcaaacgt ttctcctaat
    30661 tgctggatag atagagtttt accgatggac atcaattcac cgacaataat gacaatgaca
    30721 gaaatcaaaa agattgtttt gaacagtcct aggtggtttt tcagccattg tatggtattt
    30781 tttaacaaat aaatcacctt ctattcctaa tagttatgtt tcagaaagaa attgaagaac
    30841 ttctcgattg aagcgttcag gatcttttct agctaattca tgtccttgtt ctttcacaag
    30901 cacaaaggaa gcttttggta tagttttagc tatatacaaa gaatgtttta gcttgattac
    30961 atcttttttt cccacgatga tcaaagtggg ggagttgatt ttttttaaat cattttctgt
    31021 aagcccgatg tcatgcagca aaagtttgat aactaaaaga tttttgcgaa gacttgggcg
    31081 aaataaagag agtaaccata cccatgcata atgaatatta ctgatgactc tggcagaaaa
    31141 acgaacgcct ttaacaagcg tgtttccaga atttaaaatc aatcgatgaa cttttttagg
    31201 gaagctgctg gcaaatacca gtgctagatt tgctccatca ctaaatccaa gaaaatctgc
    31261 ctgatcgatt ttttccagca acatgatcgt attcagatcc tcggccatta actgaaaatt
    31321 caacatagat gcttcgtttg tcgaacgacc atgtcctcgg ctatctacta gatacacggt
    31381 atagtagcgt tcgagtacag ggacctgttc tgaaaaaaag cggccgctgc cgtcattgcc
    31441 atgcagtaaa aagagaggga agccttgacc gctcttttca tagtaaattt cgctcccatc
    31501 tggcattttt gcatatttct tttctttttt cacataatca cctactgtgt aaagtataac
    31561 gattatatca gtcattgggc aattgttttt actgaaaaac aacgatcatt ttcgtaagat
    31621 gtcaaaaaat acaggaaaat tcattttttc ttaaggcgta cacagaaatc aaggaagaaa
    31681 tagccaagaa gataaagaaa tagtaagata aaaaaagatg tcaaaataac taggtgatga
    31741 aatgaagcga aaacgattat ctattatccg tattcttttt tacatgatca ttctgacggt
    31801 tattggtgcg gtgttgtttt taggaggaag aacttatcgt tcggtaaaac gagtggaaag
    31861 ctatcaaata gaaataacaa cagctgcaaa aaattatcat atggaaaact acgagaattt
    31921 gatcaaggcg ataatattga ccgaatcaaa aggaaaaggg acagatctca tgcagagctc
    31981 ggaaagtctg catggagaag ctgagatcat tgataatcca gctgacagta ttgatcaagg
    32041 tgtcaaatat ttggcggaaa tgatagtaga agcaaagaaa caaggatgcg atttatggac
    32101 agctgtccaa gcatataatt ttgggaaaga ttatattgcc tatgtaaaaa atcatggcgg
    32161 agaaaacaca gtagaattag cagaagcgta ttctaaagat gtgctgagcc cacttttagg
    32221 aaatgaggaa gggaaacaat accgatattg gcggatccag tccttgcttt acaatggcgg
    32281 ctatctctat cataatggag gtaacatgtt ttatcctgat attgtcaaaa tgaatgaaaa
    32341 aataatagag acctatgaaa aagtctttaa gtaaaatagc aggaaatgtt caatcatgaa
    32401 taaaattaaa tgaaagaagg agtgcgcaaa tagtggaaaa aaggcaaaaa atggaaaatc
    32461 aagaagtggg gtacacaacc aaagactgga tgttacggtt tgtgaaggga atgtttatcg
    32521 gttcaggatt tatcttgcca ggagtcagcg gtggtgcatt agcagctgtc tttggcatgt
    32581 atgagcggct gatttctttt ttagcccacc ttacaaaaaa tttcaaagaa aatgttttgt
    32641 tttttctgcc tgttggtcta ggcggagtga caggcatctt tctactttct tttttagtca
    32701 gttttttatt aggtgcgtat gaaacaacga tattatggtt ttttgtcgga tgtatcgctg
    32761 gaactgttcc tgcgttatgg aaagaagcag ggaaaaaagg aagagatact tctgatgtga
    32821 tcatcatggt tgttactttt gttctggctt atttgttttt attatacggc gctcaattat
    32881 ttgacgggca agtcgatcag aattttggaa catggctgat tgccggcgga ttgattggtt
    32941 tgggtatgat cgtcccagga ttgagccctt ctaatttttt ggtgtatatg ggattgtata
    33001 aagcgatggc tgacggattt aaagaagtac gacttgaagt gattgtgccg atcggaattg
    33061 gtgggattct ttgtgttctt ggattgtcaa aaatcatgga ttacattttc tcaaaggcat
    33121 atagcaagct attccatttc attttaggtg tagtttttgc ttcaacgatt atgatcattc
    33181 ctaccgatta cgcgggattg ggagttgctg gggtactagc ttgtcctgtt ctttttatag
    33241 ccggtacagc actaggttgg tggatgagcc gtttggagga acaatataag taaagataga
    33301 ttgataataa aaacagcaca cgggtgattc aaacaaaaag gttggcatct tttttgtaaa
    33361 atcattcgtg tgtttttcta taaattttat aaaaacaagt tgtttttaat cttggaacac
    33421 gctagactta aacacgtgat tatttttgaa agttggcgga aaatggagaa aaagaaaatg
    33481 aatggactta cacagcaaga ggtagttcag aaaatggctt ctggccagca aaatgactac
    33541 caggaagatg catcaaaaag tacaaaacaa atattcagcg ataatatatt gacgttattc
    33601 aattttctga actttggtat tgggatttgt ctgttatttg taggtgcgta ttccaacatg
    33661 gcgtatttag caattattgt cgtcaatatc gttattggaa tttatcaaga aatacatgca
    33721 agaaatcttg tacggaaatt atcgattgtt tcccaatcag aagtactagt gatccgggac
    33781 ggtaaagaac aatcgatttc tactaaagag ctggtattag gagatttggt aaaaatcgga
    33841 gcaggagaac agataccagc cgatttacag gttatatctg gacgggcaga agcaaatgaa
    33901 gctcttttga caggcgaatc tgatttgatt gtcaaagaaa ctggagctga attgctttct
    33961 ggaagctttt tgacaagcgg ttctgtcatg gctgaagtta tccgagtagg tgcagataat
    34021 tatgctgtcc gcttgactag cgaggcaaag actcacaaag ctattcgttc tgaacttgta
    34081 gattcgattc gcaaagtatc caaattcact agtttcgtga ttattccttt ggggatcata
    34141 ctatttttgg aagcactgtt catccgcgat gcttctatca aaatttctgt tattgcatct
    34201 gcagcagctt tgttaggcat gcttccaaag ggtttggtat tgctaataag tattgcatta
    34261 acgacagggg taaccaaact ggcaaaaaaa cgaatccttg ttcaagacat gtattcaatt
    34321 gaaacgctgg cccatgtcga tacattatgc ttggataaaa cagggaccat tactgaaggg
    34381 aaaatgagta tccagcgggt agaagcacta catccgctgt acgagaaagc catcccagaa
    34441 attatgggga cgtatctggc agaaagcagt gataacaaca tcactatgcg ggctatgaga
    34501 gattattttg agctttctaa tcggtatgat gtgacaaaca aagtcgcatt ttcttctgat
    34561 cgcaaatggg gcgcgatgga atttccagaa ctgggagtcg tgtacgtagg agcgcctgaa
    34621 cgtttggtgg aagaagatcg gcttccggac agtctaaaaa cagcccaagc gaatggctat
    34681 cgcgtactta tgttggggat cgctccaaat cagcaattga acgaagaaaa accagcattt
    34741 gttgagccgg ttgctctgtt tgaaatcgat gatccaatcc gaaaaaacgc tcaagaaaca
    34801 ctagcttatc ttcatgagga aggtgtggat ctgaaagtga tttctggaga caatcctttt
    34861 actgtctcca atatcgctag acgtgcagga ttaccgaatt atgatgcgta tgtcgatctt
    34921 tctcaaatta ctgaagaaat ggaagtgcga gaagctgctc atcgctatac ggtttttgga
    34981 cgagtgagtc cgcagcaaaa gaaattgctg gtaaatgaat tgaaagaaag cggcagaacg
    35041 gttgcaatga caggcgacgg tgtgaatgat gttttggcgt taagagaagc agattgcagc
    35101 attgctatgg cagaaggtga tggagcaaca cgtcagattg cgaatctggt attgttggac
    35161 tctgatttta ctacattgcc agaagtcctg tttgaaggac gccgagtggt caacaatgtg
    35221 acgaaagtct caggcatctt ttttatcaaa acgatttatt catttatttt atcgattata
    35281 tgtgccgtta cagcaattgg atttccgttt atccctatcc aaatcacgct gattgattta
    35341 gcgattgaag ggtatccttc cttcttttta tcttttgaac aagataaaag aaaaatcact
    35401 taccgttatt tgcctacagc acttattaat gctttaccaa atgccttgct tgtagtagtg
    35461 aatatcattg cggtgtatct acttggaaaa acattcgcat ggggaaatgc tgaaactact
    35521 actttgatgt attacttgct gattgggatc agttgcatgg cagttgtaaa agcttgttat
    35581 cccttcaacc cattgcgcat cttcctagca gtaacgacga tcgtagggat atatgtagct
    35641 gcaatgctgt tccatggaat tttggaagta aacttagggt tgggagagag cgtaggatac
    35701 ttctttgtat tcatgctcgt aaatattgtt cttcgagtat tgtactggaa ggctgatatt
    35761 caaaatcagt tactgaaaag agtagcaaat tgatgcttaa tgagatagaa atgtgttata
    35821 cttgaaaaag caatgaaata tgatacaatc aaacatgtat aattgtgtcc tttaaaatcg
    35881 cactgatttc agttagtgcg attttttacc ggttattctc ctgaaatatc ttctgttaaa
    35941 cccaaaagat atcaatagag cagggggtga aaaaatggct caacggattc ctcaagaggt
    36001 tatcgaaaca gtacgcagtc aaacgaatat cgttgaggtg attggacaat atgtccagtt
    36061 gaaaaagtct ggtaaaaatt acttggggct gtgtcctttt catgaagaac gtacaccgtc
    36121 tttttctgtt gcagaagaca agcagatttt tcattgcttt ggttgtggta aaggcggaaa
    36181 cgtgtttact tttcttcaag aactagaagg tctaagtttt ccagaagcag tggtaaaagt
    36241 ggcagacttc gaacagatac cgttagaaga tcaatggcgt cagcgtacta tagctgtcca
    36301 aaatcctgaa tctgctacgg ggaaactgat tgctgctcat gaaaaagcag cggaaatcta
    36361 tcatcacatg ctattgcata caaaagctgg acagccagct ttagaatatt tgcaaagtcg
    36421 tgggttgtct ttagaattaa ttgaagaatt caacataggt tttgcaccta atgagcgttc
    36481 ttttcttcag caagtattca agaatgaatc aatttcaaat gaattgttag aacgctctgg
    36541 attgtttgtc acgcatgatg atggccgtat gtctgatcgt ttttatcaaa gagtgatgtt
    36601 tccacttcgt aattctcaag gccagacgat cggtttttca ggacgctggc ttgcacctga
    36661 aaaagggcag gaaaaagatc agcccaaata cttgaatagt ccagaaacag aactgttcaa
    36721 taaaagacaa gttttattta atcttgataa agcaagaagc gatatccgga aaaacggaga
    36781 aattttgttg ttcgaagggt ttatggatgt gattgctgca tggcaggctg gtatcaaaac
    36841 tggattagct tctatgggga caagtctaac agctcaacag atccaacaaa tggaaaagct
    36901 gacgaaagaa ttggtctttt gctatgacgg agacaacgca ggttttgaag caaccaatcg
    36961 agggattgaa ttgcttcggc aaaacagtcg attagcactt tctgtcgtag tcgttccaga
    37021 aaagcttgat cctgatgaat atctccgtaa gtatggagaa gcatctttcc aagaattagt
    37081 ggctcatggg cgcgaaacag tctttacttt taaatcacgt tatttaaaac aagggaaaaa
    37141 tttagataat gaaaaagaca agatcgaata cctcgaagaa ttactagttg aacttagccg
    37201 agttgtttca ccaatcgaac aagatatgta tctatctcaa ctgtcaacag agtttcagat
    37261 cggcagagag acgatacaaa aacaactgcg cgatcttcga aggacaaatc agcaaaatcg
    37321 tcaagaacct caggaaagtc aacacactca ggttacgaga caagaaactg cacggaaaaa
    37381 gagacctttg acgcaagtag aaaaggcaga gcagattcta ttatatcgtg catttaaaga
    37441 agtttctgtc cgtaatattt taaaagaacg agaatttcag tttattcatg atgcatatgc
    37501 agaagtttat tttttattcg atgcatatgt ctcacaacat tatgaattca accttgcaga
    37561 gtttttagac tttttgcaag atgaaaattt aaggcggttg gtggtggaaa tcgaatattt
    37621 accggtggca gaagaaagtt cgccacgaga aatccaagac ttgctagatg tgatcagcaa
    37681 atctggctta gctgatgaaa taacattaaa aaaacaaatg cagcaagaag ccagacgaac
    37741 tggaaacaaa cagcttgagc ttgaattgac gattgaaatc atcaatttaa cgaaacagtt
    37801 aaaacaagcc aaatagctac tcaagggggg ccttctttta tggcaaatgg aacagataaa
    37861 aaaacgtatg aagcagcagt agcagctttc atcaaagaaa acaaacccaa acgacaagtt
    37921 gtatatgatg atttatccaa tcagcttgct acaccattca ctttgaatgc agatgaaatg
    37981 gacaaattga tccaaaagat tgaagacgca ggtatcagtg tggtggatga aaatggtgat
    38041 ccatcaattc acagcttgaa gagtgctgag aaaaaagctg aacaagcaaa aacagaagat
    38101 ctttctgcgc caaccggtgt aaaaatcaat gacccggttc gtatgtatct gaaagaaatt
    38161 ggccgtgtct cccttttaac tgcggaagaa gaagtagcgt tagcattgaa aatcgaagaa
    38221 ggcgaccaag aagcgaaaca gcgtctggca gaagcaaacc ttcgtttagt agtaagtatc
    38281 gctaaacgtt atgtaggacg aggcatgcag ttccttgact tgatccaaga aggaaacatg
    38341 ggactgatga aggcagttga aaaatttgac taccgcaaag gatttaagtt ttcaacctat
    38401 gctacatggt ggattcgtca agccatcact cgagcaatcg ctgaccaagc acgtacgatc
    38461 cgtattccag ttcatatggt tgaaacaatt aataaattga tacgtatcca acgtcaattg
    38521 ctgcaagacc ttggaagaga acctacgcca gaagaaatcg gtgcggaaat ggatcttcca
    38581 acagaaaaag tccgagaaat cttgaaaatc gcgcaagaac ctgtttccct tgaaacgcca
    38641 atcggtgaag aagatgactc tcacttaggt gatttcatag aagaccagga agcaacaagt
    38701 ccagcagaac acgcagctta tgagttacta aaagaacaat tggaagatgt actagataca
    38761 ttgactgatc gggaagagaa tgtccttcgc ttacgttttg gtttagatga tggccggacg
    38821 agaacattgg aagaagtagg gaaagtgttt ggtgttactc gggaacgtat tcgtcagatc
    38881 gaggctaaag cattaagaaa attgcgccat ccttctcgtt caaaacaatt aaaagatttc
    38941 ttagaataag cgtggactat tgaccagaag agaaatcagt aaaactgttt ggtttatttt
    39001 aaaagaaaaa aagcttgaga ctacgcagtc tcaagctttt ttttctatag gaaggaaatt
    39061 cattcattat ttttaagtaa atcctaaaaa taagctattg gcgtgacgta tagaatatga
    39121 tagattaaat ggtagcgtaa acctagtaaa ggagccgatc gctaagtgat gaaaaaatgt
    39181 ccaaattgcg gatcgaaaaa aatggagcag aatactatct gtccagactg cggtcatcaa
    39241 ataactgcag aagatcagca aataaaagaa tcaattgaag aaacaaatac agatgcagct
    39301 atgcaggata aatcaactga agatgcagtc tttcctgata cagaattaaa cgatccaatc
    39361 gaatggtcgg aattgaaaga tttacctcta gaatctgtaa tggaattatt cgaaaaagca
    39421 gaaccagaag acgaagaacc acctgctcac gatcaagtaa ctaatataga gaaaaatgaa
    39481 cagaagaaag caactgttca tgagacttcg gaagaatcag gaaagaatca agaagaaacg
    39541 cttgaatcaa aacaaaaaag aagagtagct gaactgaaag aaatcgtcga taatgaggaa
    39601 gaaaattcga tactatccgc ttatatcaaa gcacatcgtg aagatacaaa agaagagcac
    39661 gcgaaagagc tgctcaaaat gatcagtgaa aaaattgcac aggaaaacaa agtagagcca
    39721 gaaaaggaac aagaaactga aaaagactct gatagagaaa acgccacagg taaagaaaca
    39781 gtaaaaataa aagacgtaaa aacggatatc acagaaaaaa ctgaagtatt tactgaaaaa
    39841 caattagaaa aggaaaaaac gaataaactg ccggaagcag agaaaaaaga aatactcgaa
    39901 aacacagaca aaaagtcaac agagcccgat gaaataaata gtgaatccga tgctgaaaat
    39961 caatctgtaa gcaaagaggg tactgatctt gaagcaaaaa tagaaaaaga agagaaccag
    40021 cctaagctgt ttgaagcaga agcgaaatca ataacaatcg tgccagatac tgaaaaaaca
    40081 catcaagaat caaacttaga aaaaacagat ccagataaag cgcaaaagaa aaaatcaaaa
    40141 aaagtacctt atctcgtttt agcagcagta cttctactcg gtggaggaag ctgggcttat
    40201 tatgaccatc atcaaaaagt agaagccgaa gtagcagcag aagcaaaaag acagcaacaa
    40261 atggaagaac ttcatgagaa acttgctgcc ttttatacag atgatcacca tcaatttatt
    40321 cgtgcagata tgattcatca agatttatca aaactaaaaa atgatttatc cagtcttaag
    40381 aatgaaaaag gatattcaga gttagaaaca acttaccaag atatccaatc taagatccga
    40441 gatatccaaa aagtgaatga gtggttcata gcacctgcca tcgtcgatga tcatctagca
    40501 gatgacatca agttgaaagc agataaagag atccaagcaa tcgaaacgga taacacagat
    40561 tttggaaaat tgattcaaca agcacaaaca gaagctaaaa atcaatatgc tgaattgcaa
    40621 acagctaaag aaaaaacagc tatagtcttt aaagacggaa aagtagtgga ttcagcaaca
    40681 cgcgaccaat acaagacggc aaaagaagca gtagaaaaag tgaaaaatac agatctatct
    40741 gctcagttga atgaacaatt gaaacaagta gataagatgc tcactgataa agagaaaaaa
    40801 gaagaagagg aaaagaaaaa agcagaagaa gcgaaaaaag cagctgaaga acaagcaaaa
    40861 caagccgctc aagcagcagc tgcagctcaa gccgctcaac aagctgcggt cgcacaagca
    40921 gcacagcaag aagcggcatc ctcgacccct tcctcttcaa actcagcgaa tcagccaatc
    40981 aaatctgcca gagcaagtga tattgccgat gcatctaatc cagcatggac gtgggcacca
    41041 ggtgtccaaa gcaaagtgat tgctacatgt atccaacgtg gatatatcgt tgaaggaggt
    41101 tacagattag aaaaagccag aatcgaaaat ggggaaggct attataatct atatgccact
    41161 tcaacaaaat ctgcattgat gaaaggcatt ggagaaagtg ctttgccatt ttacatcgta
    41221 accatcaact gtaaaactgg atggttcgga ggaaatggga gcaattaatt ttaggcaaat
    41281 gaaagaggct gtgagcctgc cgtttaacac cgtttattcg aaaaagggga gtatgacaca
    41341 actgttgtca tactcctttt ttcacctttc caaaccaagg ctcagctatt caagtagata
    41401 acattatgtt atgatagcaa agaaatgtat taagaaaacc tttcactata gagggagaaa
    41461 aaaatgaacg atttattagc aactatattt acaggtatta ttattgatga aaatgaaaaa
    41521 aactactttg tccaaaaaaa cggacaaacc tttggcttaa gcaaatcaga aggtgaacac
    41581 aaaatcggtg aagcagttga aggattcggt taccaaaatc aaaaacatga aaatcggatc
    41641 actacacaaa ttcctaaaag ccgtatcggt cattacggtt ttggaatcgt tactgctaca
    41701 cgaaaagatt taggtgcgtt tgtcgatatc ggtcttccag ataaagactt tgtcgtatct
    41761 cttgatgaat tgccgacaat gacagagcta tggcctaaaa aaggggatcg cttgatgatt
    41821 tcccttagag ttgatgcaaa agaccgtatt tggggcagtt tagcagatga aaaaatattc
    41881 aaatctttaa gcaaatatgg aacagaagaa atgaaaaaca aagatgtgat aggaacagca
    41941 taccgcttga aattaacagg tacgtacgtt ttaacggaag atttctatct tgggtttatc
    42001 catccttctg aacgatataa tgaacctcgt ctaggcgagc agataaaagg tcgagtgatt
    42061 ggtgtccgac cagacggtgt actgaatctt tcattgaagc caagagcata tgaagctata
    42121 tcagatgatg cacaaatgat tttaaccatt ttagaacgtt ctgcagatca gcaaatcaac
    42181 tttacagata aatcggatcc agaagaaatc atgaaagctt ttggtatcag caaaggagca
    42241 tttaagcgcg cattaggtaa tcttttgaaa caaggattga ttacacaaga aaacggtgtg
    42301 acaaaactag tcaaaaaatc taattgagaa tcccttgcat gtttttctta actagcttat
    42361 aataatttta attaacatag tgttatatct ttttttattt gtaattatta taaattgttg
    42421 gggttgagta aatggtcatg aatgctattt cggcgatgaa aaaaacaaaa cagcagctac
    42481 atgaagcggg gtttaagctg acaccgcaaa gagaagctac tctgcttgtg cttttggaaa
    42541 atgagaaaga gcatttatct gcagaagaaa tcttcttttt agtgaaaaaa aagagtccgg
    42601 aaattggact tgctactgtt tatcgaaccc ttgaaatctt gacagaattg aaaattgtcg
    42661 ataaagtaag ttttaatgat ggattagccc gttatgattt gagaaaagaa ggcgccaaac
    42721 atttccatca tcatttacta tgcttgaact gcggcacgat cgaggaagta gaagaggatc
    42781 ttttacttga agtggagcaa gtagtagaag aacgttatca ttttttagta aaagatcatc
    42841 ggctaacgtt ccatggaatc tgtcaggaat gctatgaaaa agaaaaaaga aaccagtccg
    42901 tctgagtgtc tagacggctt tttctttgct cagattatgg aaaaagacta tcagaatgaa
    42961 gcggtatctg atatgataga gaggcatgag ggggattatt atgaaagagc aaatcaacga
    43021 ttatctccac tacttgaata ttgaacgggg attgtccgcc aatacacgac aaagctatga
    43081 acgtgatttg gaacagtact tgcattttct acaggagcag aaaattgctt catggcagga
    43141 tgtcgatcgc tttttagtca tccgttttct ggagaagttg catgaagaaa aaaaagcgac
    43201 agcaactgtt actcggatga tctcaagtct cagaagattc catcagtttt tacggcaaga
    43261 gcgtatcact gatcatgatc cgatgcaaca tatcgatacg ccgaagaaag cacagaaatt
    43321 accaagtaca ttgactctga cagaagtaga aaagctgatt gaagcacctg atacgacaaa
    43381 aacgttaggg ataagagatc gtgcaatctt ggaagtcatg tatgctactg ggatgcgcgt
    43441 cagtgaattg attggattga aattgggaga tcttcatctt tctcttggac tggtacagac
    43501 agttggaaaa ggagataaag agcggatcat tcctttaggt gattatgcga tccaatggct
    43561 ggaacgctac ttagacgaag cacgtccatt acttgtaaag gacgcatctg aaatgcatgt
    43621 atttgtcaat aatcatggga aaggtctttc tcggcaagga atctggaaaa atctgaagca
    43681 gttagtacga gaggctggga tttacaaaga agtaacacca catacgctgc ggcatagctt
    43741 tgccacacat ctgctagaaa atggagctga tttgcggaca gtacaggaat tgttaggtca
    43801 cgcggatatc tctacgactc agatttatac acatatcacg aagaaaagaa tgacggatgt
    43861 ttataagcag cattttccaa gggcttagtc ataggaaggt gagaagatgt taacacatta
    43921 ccggaaagaa aaccgtaaaa ttgctatggg actattgagt ttccataaga aactgacagg
    43981 taaaacttct ttgttgaagg agattgatac gtacgaatct gaagacgatt atgaactttt
    44041 tttctttacg ccagaaggtt caaccaacat tcaagggatt attggtattt actgggcaac
    44101 gaacgatcag ctgatcatcc atgacatttc tttgaatccg tcttatcgcg gtgagaatat
    44161 gggctttcaa atgttagatg aattacagga aaagtacccg gatgtctcca tccgtgcaac
    44221 tgaaatcaca gagccttaca ttggaaaatg gctagcaaag aaaaagaaga aagagtgaat
    44281 gagttgacgg agatcaatat taaattagat gtattcgagg gtcctctcga tctgctgctt
    44341 catctgattc agcaaatgga aatcgatata tatgatatac cgatcgctac gatcacggag
    44401 caatatatga attatatcca tacaatgaaa acactcgagc tagctgttgc aggagaatac
    44461 ttagtgatgg ctgctacatt gatggcaatc aaaagcaaga cattgcttcc tgtccaagaa
    44521 ttcgtcacag acgatgaaga attatgggaa gaagatcctc gagaagaatt ggtcactcag
    44581 cttttagaat accgtaaata taaatatgca gctgaaagac tgacagaaaa agcagaggaa
    44641 cgaagtcttt attacacaaa agaacctatg aacatcgatg ggttagcgga tgctgaaaag
    44701 ccgttgaagc gaggacaagt caaaaaaatc gatttgatcc gtgccatgca gaaaatctta
    44761 gaacgtaaga aattttctca aaaagtggaa aaaacgatca cgcccgatga cacaacgatc
    44821 gaagaacgaa tggtatttat cgaagagcgt ataaaaagaa atgcgcatgg ctgtactttc
    44881 gattcttttt ttgagtcacc ttctaaaagt gaagttgtca ctacttttat ggctttgcta
    44941 gaattgatga aaaaagggca gatcattgcg caacaaaaag aaaactatga atcaattatg
    45001 ctttatccag cagtaggaga taccgaacat gacgaaatta agtgaacttg aagcccttct
    45061 ttttattgtt ggcgaggaag ggatcagtaa tgaagaatta agcggactgt taaatctcag
    45121 cgaagcagaa gtcacaagtt tagtgaaaga attaaaagaa tcttacactc aaaactcgca
    45181 ctcagctttg catatttttg aaacggaaag ccattatgta ttaacgacta aaaaagagct
    45241 ggctccctta cttaagcgat atgcgcaagg gacatcaaac acattatctc aagccgccgt
    45301 cgaaacctta gcaatcatcg cttataaaca gccaatcaca agagctgaaa tcgagcagat
    45361 tcgaggagtt caggtttcag gagcggtaca gcgtctagct gcccataaac tgattgaaga
    45421 aaaaggtaga gtagaaggac caggtcggcc gatattatat ggaacaactg gctacttctt
    45481 agattatttt ggtttgaaat cattagaaga actgcctgat acacaagaaa tggaaatttc
    45541 acttgaagaa gacgtgtcac cagatctatt ctttgatgga atgaataaag gagaataatt
    45601 gtaatggaga gattgcagaa agtaattgcc cacgctggca tcacttctcg tcgaaaagca
    45661 gaagaattca tccttgcagg acgtgtaaaa gtaaacggac aagttgtaag ggaattaggg
    45721 ataaaagttg ggaaacatga cactgtggaa gtggatgaag tcccaattta tcaagaagaa
    45781 tacggttact atttattgta caaacctaaa ggagttattt ctgctgttgc agatgacaaa
    45841 ggaagaaaag ttgttacgga tcttttgccg atggtaaaag aacgtatcta tcctgtaggt
    45901 cgactggatt acgatacttc ggggatcttg ctactgacaa atgatggaga ttttgctcag
    45961 cgcctgacac atccaaaaca tgaagtggat aaagtttacg ttgcaaaggt aaaagggatc
    46021 gctacaaaat cgatgcttgc acctttgaca aaaggaataa agatcgaagg acgaaaaaca
    46081 tctccagcta aattccaaat tttatcagtg gatcctaaga caaaccacag tatcgtggaa
    46141 ttgacgatcc acgaaggacg taatcatcaa gtgaaaaata tgcttcaagc agttggtctt
    46201 cctgtgcaaa aactaaaacg tgaaaaatac ggagatctga ctttacaagg cctacgtcct
    46261 ggggattacc gtgaactgaa caaaaaagaa gtcagcagtt tgctgaacca ctcaaaatga
    46321 acacttactt tttataagtg ttagatgttg cgttttttga atagatatgt ataatgaata
    46381 tgtaaacaaa aattatataa ggttcgtctt caggggcagg gtgaaattcc cgaccggtgg
    46441 ttatagtcca cgacctattt tgcaaaaaaa tagctgaatc ggtgaaattc cgataccgac
    46501 agtatagtct ggataaagaa gatagagctt atttgacgac gcttgatcaa ataactctaa
    46561 ctctattttc cctggaaaat agagtttttt catttggaga gaaacgtcaa aaagttcgct
    46621 gaagaggagt cctaacagga ggatttcaaa tgaagaacac ccgtgtacag aaaatggttg
    46681 cagtagcgat gtttgctgcg atcgcattag ttttacagta ttttgctttt ccgatcatgc
    46741 cggcttttag ttttttgaag atcgatttta gtgatatctc ggtattgatc agcatgttct
    46801 tattcggtcc agcggccgga gttgcaacag cgttcttgcg ttcagtatta catctgctga
    46861 ctacaggttt ttctccggat aatttggtag gagacactgc tagtttctta tcaacaacga
    46921 tctttacatt cccgatttat tatttcttta gtgtaaagaa acagcataaa ggaagaaaca
    46981 aatttttagg tgtcattaca ggaaccatcg ctctaactat ttttatgagt atcgcaaatt
    47041 atttcgttat tacgcctctt tacttaatgt ttttagggct gaacgcaaca cagatgctgg
    47101 gcatgtcttt agcaaactat gtactgattg ggatcgttcc tttcaacttg atcaaaggat
    47161 tcatcgtgag tgctgtcttt ttagtgctgc atgcgcaact tcttccatgg ttaagtcgaa
    47221 aacaacatca gttcgaacaa cgtcatacag cagtcaaata aatatcaaaa agatcaagaa
    47281 atttcttggt cttttttttt ggaaaaaaat acaagacatg caataatgta aacgttttat
    47341 ttgtttgttt tgagtatttt tttgatttat gcataaaaat caatcaattc tttgcaaatg
    47401 tgaaattctt ctccttttaa aagacgaaaa tgtttgttta taaaaaaaag gaaacgctac
    47461 aatgaaaaag aagaaagctt taaaaacctg aaaaaagagg agggaatagg gaaaaacgaa
    47521 ctttttgaac aaaagtttta caaaatgcgt gttattattt ttgttctgat actctttttg
    47581 ataaaataac attagagcca aaattgttgt ctctaacgga aaagaaagga agaagaagat
    47641 ggaacaaaca aaaaagaaaa aatttcaaat gccttcagcg tatacggtct tatttattat
    47701 tattgcagta atcgctgtac ttacttggtt tataccagct gggcactata gtgtagacga
    47761 tgcaggcaac atcgtcgctg gatcatatga acgagtacaa caaaatcctc aagggctgtg
    47821 ggatattttc atggcgccaa tcaatgggat gctaggtgta ccagcggggg agctaactaa
    47881 agaaacacct gctgcaatcc caatctcttt cttcattttg gttgttggtg gatttttagg
    47941 tattatcaac aaaacagggg cactagatgc cgggattgct tcagttgtga agaaattcaa
    48001 aggaaaagaa aaaatgctta ttccagtatt gatgctgtta tttgcattag gcggctctac
    48061 ttacggaatg gcagaagaaa cgattccatt ctatgcttta ctgatcccag tcatgatggc
    48121 tgtaggcttt gatacagtag tagctgtagc aatcgtatta gtagggtctc aagtaggctg
    48181 tctagcttca acggtaaatc cttttgcaac aggcgtagct tcacaagctg ttgggatttc
    48241 gatgggtgaa ggtattggtc ttcgattctt gatgttcgtt attttgttag ctatttctat
    48301 tgtatatgtg tatcgttatg catcaaagat cgaaaaagat ccaacaaaat cattagtata
    48361 caaccaacgt aaagaagata tgaagcattt cgatattgaa gcaatcggtc gtcaagaagt
    48421 aatcacgaaa aaacaaaaac atgttaatgt attgttcttt attacttttg gtatcatgat
    48481 catcagtttg attccttgga caaccttgaa tgcgaatttc acgatttttg aatcattgac
    48541 aaactggtta acaaaccttc cggtactagg tacggttcta ggtaaaagca tgcttccatt
    48601 aggtgactgg tacttcccag aaattactat gttattctta gtaatgtcca tcgtagtagc
    48661 aatcacttat ggcatgaaag agtctgaatt tgtctctgaa tttttagctg gtgcttctga
    48721 tttgatcggt gtagcaatcg tagtagctgt tgctcgtggt atccaagtgg ttatgaacaa
    48781 tggattaatc acagacacca tcttacattg gggcgaacaa ggattaagtt cattatcttc
    48841 aagtgtattc atcattatta catttatttt ctatatccct atgtcattct tgattccttc
    48901 aacttccggc ttagctgctg caacaatggg aatcatggga cctatgggtg aatttgccgg
    48961 cgtcggtaag gatttagtaa tcactgctta tcaatctgca tctggtttag taaacttaat
    49021 tacaccaaca tctgctatcg taatgggtgc tgtagcaatt gctcgtttcg atgtttcagt
    49081 gtggtggaaa tttaccggta aattaattgc gatattattt gtagccatct gtgtgatcct
    49141 aggtgtagca gcaatgttct aaacctagac aaatacaggt acaaggtcta tcataagaat
    49201 gaagaaaccg ataaacggct atcgataagc acgtggataa gtcaatagct ccattcagtg
    49261 agtgtttttt ctttcatcat ttgttaagaa cattctgctt gctgatggag caggcttaaa
    49321 acgtcattat ttgagaagaa gaggttgtgt cggaggaatt tgacatgacc ctttttaaca
    49381 tattaggagg ataatatcat gaaaaaattt gtgacagaac aacatcatga acaagcatta
    49441 gaatcattga gcgaattgat ccgaattcct tccgtactag atgaagcaga ttcaggacaa
    49501 ggacatccct tcggtaaaaa agtgattgaa gctttggata aagtattgga aatcagtgaa
    49561 aagctaggat ttagaacatt taaagatcca gaaggctatt acggttattc agagattggc
    49621 tctggagatg aattattcgg tatcttgtgt catatggacg ttgttccagc aggggacgaa
    49681 aataattggg aaacaaaacc attcgatcca actataaaag acggctggtt agttggtcgc
    49741 ggatcccaag atgacaaagg tccttctatt gcggcaatgt atgccgtcaa agctttgatt
    49801 gatgctggcg tggaattcaa gacacgtatt cgttttatct ttggtacaga tgaagaaaat
    49861 ttatggcgtt gtttagaaaa atataacgaa aaagaagaag gaattacgca aggatttgcg
    49921 ccagatgctg aatttccttt aatttatgca gaaaaaggct tattgcaagc ttacttgaca
    49981 ggaccaggaa cgaacgagtt ttctgtaaaa gctggaggag cgttgaatgt tgttcctgat
    50041 gcagctcctt actctggaga aaagctttct gaagtaaaag aagcattgaa aaaacacgaa
    50101 ttcgatttcg aagaacaagg tgaaggcatc gtcgttcttg gtaaaagtat ccacgcgaaa
    50161 gatgcagcac aaggagtgaa tgctatttct cgtctggcaa ttgctctttc agaagtattt
    50221 gattttggcc caatcaattt cttaggaaaa ttagttcaag aaaatgcaac tggtgaagct
    50281 gtcgtgggca aaacagaaga tgaacaatcc ggcgagctaa cgatgaactt tgcaagtttg
    50341 gaaatcacac cagaacaaac aaaaatcggt gtagatatga gaatccctgt tacattcaag
    50401 aaagatgatt tagtagctaa attaactaaa acagcagaaa aatatgggtt gacttatgaa
    50461 gaatttgact tccttgattc attatacgtg ccactagaca gtgagttagt gaaaaatcta
    50521 ttggggacat atcgcgatat tactggagac atgactgaac cgtttgtatc aggcggcgct
    50581 acttttgctc gtacgatgaa ccagtgtgtg gcattcggtg cgatgttccc tgatactcct
    50641 gactttatgc accaggcgaa tgaacgatgg gaattaagta gtatgtataa agcaatggaa
    50701 atttatgcag aagctgtgta tcgtttatgt gctaaataaa aataaacata caaaaagggc
    50761 ggatattcaa atggatattc cgtctttttt tatttgatgc tggaaagttt gcatttctct
    50821 cttatttttt taaggtataa tcatacttga ttaagaaaaa ggggtcactc agatagaaaa
    50881 ggtgggagaa agtgaaaata tttagacgaa tactaattgg cttagtcatc attttaggat
    50941 tactcggtgg agccggttat tactatatac agcaaaatac gtacgaacca tcgtcagaag
    51001 cgcaagtgtt ggtaaaagaa ggaaaaaaca aagaagatta cttatttttt gaaggagaga
    51061 aaaagaatca tggaaagtct ccattactta ttttttatcc tggtgctctc gtagagccag
    51121 aaagttatag tatttgggcg caagatttag caaaaaacgg cttttcagtc gctattgtca
    51181 aaatgccact tgatctagca gtgatgggcg gaaacaaagc ggataaggtc aaagaagatt
    51241 ttccaaattc cgattatgtg atcggtggcc attcattagg tggcgtaatg gcaagtcgtt
    51301 atgtcaataa gaatcattca gacaaacatt taaaaggggt attcttcatg gcaagttatc
    51361 ccgacaaaaa aggaacattg acagaatcag ctgttcctgt tttatcgatc acggcgacaa
    51421 aagataaagt attgaatcag gaagcttatc aagaagctaa gcagtattta ccggaaagaa
    51481 cagagtatgt atcaatcaat ggcggaaatc atggaggttt tggcagctat ggtgagcaaa
    51541 aaggagatgg agaggcagaa atttctaacg cagaccagca aactgtgatc gtcaatacat
    51601 tggaaaactg gctgaaaaag ttgaaataat ataaatgggt cctatagggt ccgtgaaaaa
    51661 actagtcaat taactataga tagcaaatga atctttcaaa ataagtcggg atttcacgga
    51721 acaagagaaa cagatcccgg cttattttca agtttagaga acttagtgta cgtttttaaa
    51781 gtttcgttta tatttatatt ttattttcta ataaaatcgc tcgaactgga catttttgat
    51841 acgctttttt tacatatgtt tcttcttccg gcatcacgaa ctgttgatga gcctctggtt
    51901 cttgggcaaa taaaacgatt ccttcttcat cataatcgaa aatatctggc gcttcgattt
    51961 gacaaagacc gcatgcaata cagcgttcag gtacaagttt acatagtagt gacatttcta
    52021 accatcctaa cttaaggaga ataatatgat tgtttttatt ttatcgctat tttcatcagg
    52081 acacaagctg cggattagtt ctctttacca actccttgtg ggaaaacgaa cgacttcagt
    52141 acttatttat ggatttaccc acgaactttt gtttatccat aacagttttc cagaattgaa
    52201 gcaggataag ttttatcaaa ttttgcaaaa aattgcgcag caaggttgga tcgaaataaa
    52261 tgaaaatgaa gcaaagctaa cgcctgcagg ggctgatatg ttgtccgaac atcaaataga
    52321 acatactggt ttgcgttttg accgctatgg cagaacaggg gaaactagtt ggcggctcat
    52381 taaatttgct gttcaagtaa tttctaatct ggcaacgggt attcaagact atcttccagc
    52441 agagacaagt cctttttata ctttccaact aaaaaaatgg cttagtgaaa gccaattgcc
    52501 acgtgaaatt ttgattgata ctgcgtatga gagtttggtg cagctgtttt cggagatacc
    52561 agaagaagca gcagattttt tagctaacca attatctgga aatgagcgaa cagggctgct
    52621 tccttatcag ctggcaaaaa acaatgatga gtcagcggtt tatctgcaac aaagcagatg
    52681 tatccacctt ttgttagcac aaatcgaaaa acggccagat tcgctttggc acgctttgat
    52741 cgattcatta ttacagcaaa atttcaatca aagcatgatg atcaccaagc agatgtttat
    52801 gaatggtcag acaattgacc agatcatggc aatccgtcat ttaaaaagag gaacagtaac
    52861 agatcatctt attgagtggg ccttgttttt tgatgatttt ccatacgagt ggattctctc
    52921 tgcagaaaca atcgaacgtt tggaaccaaa taaggattcc gtgcgagagt ggcgctttag
    52981 cgaatggaat gtagatggac aattagatta tggagaattt cgtttgtatc aaatctatct
    53041 attgagaaag gaagcgatac agaatgttaa taaatgaatt aaaaaaatat tttggatttg
    53101 attcatttcg tcccggccaa gaagaaatta ttcaggcgtt gcttgatgga gaagatactc
    53161 tcgctatttt gcctacagga acgggaaaaa gcctttgcta tcaattgacg gggtatttaa
    53221 tggaaggtct ggtcatcatc gtgtcaccgc tgctttctct aatggaagat caagtgacgc
    53281 aattacaaaa acgaggggag aaacgagtag ctgctttcaa tagtttactt tcgcaatctg
    53341 aaagaagata cgtcctccgt catctatcgc aatataaatt tttgtttttg agtcccgaaa
    53401 tgttgactaa tccttctctt ttagagcatc tgaaaaaaca aaatattgcg ttatatgtag
    53461 tagatgaggc tcattgcgtg tctcaatggg gagttgattt ccgtccagaa tatcaacagt
    53521 taggaaaaat ccgaaagctt ttaggaaacc cggtcacact ggcactaacg gcgacagcaa
    53581 cagatttagt agcaagagat atacgtcatg tactatttga tcgaccacca aaagagatca
    53641 gacaatcagt caatcggcaa aatatctcgc tttttgttcg gaaaacgcag caaaaagaac
    53701 aagaacttga acacttcatg gaaagagcac aaggagcggc aatcatttat tgtgcaacaa
    53761 aaaaagaagt cgaacgattg tatcatttat tcagggaacg ttttacagtt ggatactatc
    53821 acggtggtct tgatgcagct caaagaagac aacttcaaca gcagtttgta aaaaatcagc
    53881 tgcagtttct cattgctacg aatgcatttg gtatggggat cgataaatct gatatccgtt
    53941 atgtggtcca ttatgatttg ccagacagtc tagaaaacta tgtacaagaa atcggtcgag
    54001 caggcagaga tcaggaagaa agtgcagcaa ttctttttta tcaaagtggg gatgaacgta
    54061 tccattattt ctttaatcaa ctttctagag aacagcgaca aagttttgag ctttatttgg
    54121 aatatgccac agagcaagct ccctttgatg agctgcaaaa aaaatggatg gagctgatcc
    54181 agcagtctga aaaaccagaa aattgggtgg aacggctcaa acgtcaggaa aaagaaaaag
    54241 aattccgcct gcagcagatg cttcgctata ttaatgaaga aaactgccgc agaaaattca
    54301 tcttagctta ttttggcgaa aaactctccg aaaagccgca gaattgttgt gatattgatg
    54361 gagcaaaagc agaacttctg ccaaagagga agcttttttc taagactgaa caacttcatt
    54421 gggaaacgat tttactaaat ttatttaaaa aaaacatgga acattgattt tttaggacaa
    54481 gacacttttt cctatggtat aatacacacg atagagttta ggaggtaaaa cagtgagcag
    54541 aaaagataga catcaatcta cagaaaataa cgaaacacaa gaaccatggg aacaaccaat
    54601 ctacgataca gatgatgaag tttcatcaag aagttctcag agacaacaaa agaaaggaaa
    54661 tacattattt ctttcgctat ttttgatttt actggtctta tgtatcgcta ttccagcagg
    54721 tgcttatttc tggatcagaa atggatcaag caacaatgca acagcagcaa cttcttctga
    54781 aacttcgaca tcagtagtag aaagttctac aagtacaaca aaagaggagt caactgagac
    54841 ttcaacagta gaatctagta caatcgcgga agaatctact gtgtctcaag atacaggtgt
    54901 aacgtcagaa agcagtattg cagcagagac aacaccgact tcctcaagtg aggcaactta
    54961 tcaagcaggg gattcaagca gcaatgcagc agaaacaaca ccttcttcat cagctgcagc
    55021 cggttcaaca acgactgttc aagcaggcga aggtccaaaa caagtggctg agcgtgcagg
    55081 gatcaccact gatcaattgt ttgaattgaa tggcttagat ccaaacaact ttatgcttta
    55141 ccctggtcaa gaattaagaa ttaaataata atagccgcgc tttgcggctt tttttctgag
    55201 aaaaaggagt tatatcatga cacaaatcag tattgcaatc gacgggcctg cttcatctgg
    55261 gaaaagtacc gttgccaaga tattagcaaa agaattgaat tatatttata cagataccgg
    55321 tgccatgtat cgcgcagtaa cttatttagc tattacgaac aatgtatctt tttcagatga
    55381 agaagggcta gtttcgctga tcaaaaagta tcctatctct ttttcgcaac aagaagatgg
    55441 acagcatgta ttcatagcat caaaagatgt gactttagaa atccgtcaac cagatgtcac
    55501 aaaagctgtt tctgaagtct ctgcacatgg aaaagtcaga gaagaattag ttgctgtcca
    55561 acgaaaaata ggggaacgcg gtggcgttgt catggacgga agagacatcg ggacagctgt
    55621 attaccgaat gcagaagtga aaatcttttt agtagcaagc gtaagtgagc gtgcagaaag
    55681 acgtttcaaa gagaaccaag aaaaaggaat tccgactgat cttgaaacac tgacgaaaga
    55741 gatacaggaa agagaccatt atgattcaac aagggacgtc tctccgctga agcaagcaga
    55801 ggatgctgtt cgtatcgata cgactggcaa atcgattcca gaagtcgttg cagcaataaa
    55861 agctgttgtt ttgaaaaaag gttatcttct tttttaaatt aagaaaaaaa atgaaaaaca
    55921 attgtttttt caaggaaaac gaacgaaatc gctttatttt ttttgaataa tcaattaaac
    55981 taaaaacagt accgtactta cggcagaatg ttggttagga ggacaagtgt tatgacagaa
    56041 tttgatcaaa atcaagagaa caaccagtca atggaagacg caatgaaaag cgtacaagaa
    56101 gtaaaagttg gcgatgttgt taagggcgaa gttttagtca ttgaagacaa acaagtgatt
    56161 gtcggaatcg aaggggctgg agttgaagga gtcgttccgg caaaagaatt atcaactttg
    56221 ccggtagaag atatcagcga agtagtaaaa gtcggtgatg tattagattt agtcgttatc
    56281 agtacgatcg gcaaagataa agaaaacggc agctatctac tttcaaaacg ccgtttagat
    56341 gctaaaaaag tttgggaaga tatcgaaaga gatttccaag agggcaaggt catcgaagca
    56401 cctgttacaa atgttgtcaa aggcggttta gtcgttgacg tcggtgtacg tggttttgtc
    56461 cctgcatcaa tggtggaaga tcattttgtt gcagactttt cagactataa aggcaaaaca
    56521 ttgagcttta aaatcatcga aatcgaacca tcagaaaatc gtttgatctt atcgcataaa
    56581 gcggtagtgg aaaacgaaag agaagaaaag aaaaaagaaa ttctttcaac tatccatgag
    56641 ggagatgttc tcagtggacg tgttgcacgt cttactgatt ttggcgcatt tgtcgaccta
    56701 ggcggaattg acggtctagt ccatgtctca gagatttcac atagtcatgt agcaaaacca
    56761 agtgatgtat tggctgtcaa tgatgatgta aatgtcaaag tgttgtctat caatcctgaa
    56821 caagaacgtg tttccttgtc aatcaaagac acacagcctg gaccttggtc agaaatcgat
    56881 acaaaagctc cagttggcac agtattagac ggaacagtta aacgtttgac aagcttcggt
    56941 gcctttgttg aagtgttccc tggagtagaa gggctagtcc atatctctca aatttcacat
    57001 aaacatattg cgacaccaca tgaagtgctt catgaaggtg acgaagtgaa agtgaaagta
    57061 ttagagatcc atccagaaga acatcgtatt gcattgagta tcaaagcttt agaagaaaaa
    57121 ccagcttcag aagaagaacc aaaaaatgtt gagtcttatg aattaccaga agaaaatact
    57181 ggatttacta tgggagacat tttaggtgat gcgttgaaag aagaagtaga agaaaaagca
    57241 accgatgatt ctgaaaaata attgattttg tatctgtgac tgagatgaaa gcagctgctt
    57301 ttgtctcagt ttttcttttg aaaagcgatt agtatttcaa taaggaataa aaatacttcg
    57361 tttaattgac aatctatgct tgaaagttgg caatgcattc gttaaactaa gtgagattgg
    57421 aaacttgtga ggaggaaata atatggcaaa tccaacaatt gcaatcgttg gccgcccgaa
    57481 cgtcggtaag tctacgattt ttaaccgcat cgctggtgag cgtatctcga ttgtcgaaga
    57541 tactcctgga gtaactcgtg atcgtattta tgcaaaaggt gaatggttag gtcgagaatt
    57601 cagcgtgatc gacacaggcg gaattgatct tggcgatgaa ccttttatgg atcagatcaa
    57661 gcatcaagca gaaatcgcga ttgaagaagc agatgtaatc atttgtgtag tcagcggacg
    57721 cgaaggcgtg acagacgcag atgagatggt tgcgaaaatt ttatacagaa gtaataaacc
    57781 agtgatttta gcagtcaata aagtagataa tccagaaatg agaaacgata tctatgaatt
    57841 ttattcctta gggctaggcg atccttatcc tgtttcagga agccatggac tagggattgg
    57901 tgatatttta gatgaagcag tgaagtattt ctctgaagag actgaagaag aggacgacga
    57961 cacgattaag tttagtttga ttggtcgccc aaatgttggt aaatcctctt tgatcaatgc
    58021 gattttagga gaagaacgtg taattgtttc ggatattgaa ggaacgaccc gagacgcaat
    58081 cgacacccac ttcgtttctg aaagtggtca gaaattctta atgatagata cagctggtat
    58141 gcgtaaacgc ggaaaagtat acgaaaatac tgaaaaatac agcgtgatgc gtgcaatgcg
    58201 tgccattgac cgttctgata tcgttttgat ggtactgaat gctgaagaag ggattcggga
    58261 acaagacaag cgagtagcgg gttacgccca tgaagctggt cgtggaatta ttatcgtcgt
    58321 gaataaatgg gatcttgtaa agaaagaaac caatacaatg cgtgatttcg aacaagagat
    58381 tcgtgatgaa ttccggtatc ttgattacgc tccaatcgtt tttgtttctg cagtgactaa
    58441 acaacggttg gaacgtctgc ctgaaatgat cgaacaagta agtatgaacc agaatcttcg
    58501 tatctcttcg gctgtgttga atgatatcat tatggatgct gtagcaatca atccaacacc
    58561 aacagataaa ggaaaacgcc tgaagatttt ttatgctaca caagtcgctg tcaaaccacc
    58621 tacatttgtc gtttttgtca atgaagagga attgatgcat ttttcttatg aacgtttctt
    58681 agaaaatcaa atcagaaaag catttacttt tgaagggacg tccatccgaa ttatccctcg
    58741 taggagaaaa taggcatttt accatatcga cgtttttttt tcaaaagaaa aagacagttt
    58801 cgtttgttac gtttctatga ctaaaaaaag catgtgaaaa ttggtaaaaa ccttgctatt
    58861 aagcggttca tatgatatcg tgataacaga atattgaagt taatcaatat ttctttttaa
    58921 acttctggac cactcagaaa gttttaacta aatgatattt ctatcatatc tcttgtggag
    58981 gaggtgaatc tatccatggc aaacaaagca gaattaatcg aaaaagttgc ttcagctact
    59041 gatttaacta aaaaagatgc aactgcagca gtagatgctg tattttcaac tattcaagat
    59101 gctttagcta acggcgaaaa agttcaatta atcggttttg gtaactttga agttcgcgaa
    59161 cgcgcagctc gcaaaggtcg taacccacaa actggtgaag aaatcgaaat tccagctagc
    59221 aaagtacctg cattcaaacc aggtaaagca ttaaaagacg ctgttaaata agacagttga
    59281 aaaagcgctt gtggctctag ggctacaagt gcttttcttt ttatttccta gcagaaaagg
    59341 aataaataag agacagagat tccgaatccg tatgtcatac atagaaaaca catgtatttt
    59401 atttaatttt tatttatttg caagttatga ggtgagcttt gctcttatct tttctagaat
    59461 ttgcttacta atggtaaaat aaaaataaga agaggaggga tgcgtatgga acttgattat
    59521 caagtagaag atgcgttgac gaaagtgttt tacggagaaa cgctagtcag tcagctaaga
    59581 gaactttcca ttgatcagcc aatcttattt ttaacgaatc agcgctatta tgatttgttt
    59641 gcagataaga tcaacccgtt atttgcaaat caagcaaaca atgactggta tatttgtgcc
    59701 aacactcaat gcaatcattt aacagaatta aagaacctgc ttgatttcgt caaacgctat
    59761 cccgaaaatc aatccatgtt tatcatcgga tttggaaatg aagggatcat ggatctggca
    59821 ggtttttttc aaaaacatac aacccttgat tcatcactat ggatgatccc tgtatcgatc
    59881 cgttctctaa gccgagcatt aacaccgcag cggacgattt tgcagctacc aaatcgtgta
    59941 gtgctgcaaa ccatcaatct gccagaacgc atcgtttatg atcaaacaat cagcgagcgg
    60001 caggtggacg gaaagcagat tgactttttg acttttatct gttgcggaat gatttgtgat
    60061 catcgttttt tgcaaaatct gtataaaaac tatccaaata aaaagcaatt aacgactcgg
    60121 ccgtttgccg ggatgatcga agaaatgatc tatttttatc aattagaggc agaaaacctg
    60181 tcaaattatg gtaaactgtt tgaacaagct ttttatctga ccgaaaatgg ccatctactt
    60241 tctgctagta tgaaaaaatt tttaggaatg atgtttcatt tcgtgtggaa tctccaagca
    60301 tatccttttg atttccaact aaaaaacttt tttgtgtggc tggacttgct tggctatcca
    60361 atccactggc tggaacagat ttcaaagatg gagtatttgg aaaaagttct ttttttggca
    60421 gaaaaaagca aaaaaatact tgttttagaa aaaataggta taatagacgg ataccaacat
    60481 ccaaacgaaa aagaattatt gagaacaatg acggtatttc aacaaatcgt cagtgagata
    60541 agagggaatt gaaatgaata caaatagcga aaaaatgttg caagctttat cagatgaaga
    60601 cttgtcacaa gcacaaatct ttttagaaaa agcattaaaa gaagacccag cagatatatt
    60661 agctgaacta ggcgaagaat tgctggctat tggctttttg atcgaagcaa aacagatttt
    60721 tgaacaactg atcaaccaat acccagaaaa tgacggactg aacatcccgt tagcagaaat
    60781 tgcaatcgaa gataatgaga tcgacttagc ttttgaatac ctggaaaaag tggataagca
    60841 aagtgattac tatccgcaaa gcttattggc gatagctgat ttgtaccaag ttatcggaat
    60901 ccctgaagtg agtgaagcaa aattgaaaga agcagctggg ttgcttcctg atgaaccatt
    60961 gatccagttt gcgctagctg aattgtattt ttcagttgat cgtttcaaag aggcagcagt
    61021 ggtttatgaa acattgttgg caagcgggat aaatgaaatt tcaggaatct cgatgcagga
    61081 acgtttagga caatccttaa gtatgcaagg agaattcgaa gcagctatcg tacctttaga
    61141 agaagcactg aaagaagaaa ggacagatga tcgactgttc cagctagctt ttacgaatct
    61201 tcaattgaaa gaaaatcagc aggcaatcaa ctatctggaa gaacttcgag aagttaatcc
    61261 gcattatcaa tcgttatatc tatatctagg acaagctctt caagaagaag aaatgattga
    61321 agaagcacaa acagtgttag aagaaggaat caaagaaaat ccttaccaag tcgaacttta
    61381 tcacctggcc tcggaaaatg ctttccgtct gcatgataga cagcgagcag aagaactttt
    61441 actgaaagct ttagaagtag gagacaaaca agatgaaaca ttacttactt taagtaatct
    61501 ttacttggat gatgaaagat atgaagatgt gatacaagtg atcaatcaga tggaagaaac
    61561 tgctaatcct tatgcagaat ggaacctagc ccatgcttat aatgaattag aagactttac
    61621 cgttgcagct gtacactatg aacaggctta tcatgaacta tcacatgaac cagatttctt
    61681 gaaagagtat gcctttttct taagagaaga agggcagctg aaaagagcgc aagaattatt
    61741 gacttattat ttaacacttg aaccaggaga tatggaggca ctgtcattat tagatgacct
    61801 aacagagagg tgagaaaaat gctaattgat gtacgggaaa agaagaattt tttaacgtgg
    61861 atggtcaatc atgtatcttt tagccgaaga gaagtttttt ggatcttgaa ttatcttgcc
    61921 aatcatgaag cgattttaag caatgtccac tttgttgaag gggcgaattt tgcggatcga
    61981 ggactgcaga tcagtgatct atctgttgaa ggggaaccca tgaaattgtt tttgcaggga
    62041 aaagaattta cggacacaga ccagattttt catgaaatcc gtttgaattg gaaaaagcct
    62101 ttatatgtgg aatgtatatt cgaaaatgct tggcagacaa gagaatatct atctatctta
    62161 gaagacaatc cattttcttc ttgggattct tcagtcagtg aagaagatac tgaattaatt
    62221 gaacgatatt ttcaagaaaa agaagaagag gcaaaactaa aaatgcttta tgctcaaatc
    62281 gatcaagcac tagaagatgg agatagggat gcttttttga aattatctga tgaagttaac
    62341 cgaaagatcc ttttgcagac acaaaagaaa agtaaccggg taagtgaaca taacaattag
    62401 ttaaaaatag tatagtacta aaaaagacaa aggtcagctg gatgtggaat ctttcctcat
    62461 agcctatctt tgtctttttt cttatagttt tttcagtaat cttgtctgtg gctttaaata
    62521 agtaaagcct tgcccttcca cttcatgcac attgatgatt gaaaggaaag ctttttcgtc
    62581 aatctcgtgg acgatcctct tagcttcagt taattcacta gagctaacga ccatatagat
    62641 gatttttttt gaattaccag agaatgcgcc ttctccagaa aggaaagtca cacctctttg
    62701 cagaccggtc atcagtagtg gtgcaatctc ttcgcttttg ttggagacga caagtagacc
    62761 ttttgcagaa tatccgccat ctaagatcga atcaatcaca cgactgaaaa catacgaaac
    62821 aatcaacgta tacatcatac gtttcaagtc gatataggtt aatgaagcaa gtaagacgat
    62881 gatatcaaat gccaataggg aacgccccat agtgatgccg taattttgtt ctaaaatccg
    62941 agcgataata tcactgccgc ctgttgttcc acccatgcgg tagacgatcc cgcttcctac
    63001 acctgcaact aaacccgcaa gtagagaaac gatcagtaga tcatgctgta aattgatttc
    63061 tagtggaacc ctttgccaga tccataaaaa gaatgacaaa gaaagtgtac ctagaacagt
    63121 ataggccaag gaacgtttac cgaggatctt tcctcctagt aaaatcaatg ggatgttgat
    63181 taataaagtc gtataagctg gatcaatacc aaataaagct cttaagatca aggtgatccc
    63241 tgagactccc ccttctgcta aatgattagc gatgttcaag taaacaagac caaatgcata
    63301 aatacttgtt cctataatga taaaaagaac ttcttttact gtttttcgtt tgaccatatg
    63361 aattccagct ttcaattatg tattttcaca gaatttccat ttagaaattc cttcctaaat
    63421 gtagcatgga aattcgattt tctcaattgc tcttatctag gatttgcgtt aaagttttgg
    63481 taagatagtt ttggagggaa aaagatggat aaaaagcgtt ctttatacag tatgcagcag
    63541 gaagtggatg aatatatcca gcaattcaag gtggggtatt tctctccatt agctcagatg
    63601 gctcgattaa ctgaagaagt aggtgaattg gcaagagaag tcaaccacac ttatggagaa
    63661 aaaagcaaaa aggcttctga accagttaac tcggtagcag aagaacttgg tgatgtttta
    63721 ttcgttacga tgatcatggc taattcattg aatatcgact taactgaagt ttttgaaaaa
    63781 aacatggaaa aattcaatca aagagaccat aatcgctttg agcgtaagga cgagtaaaca
    63841 agatgaagtg gtcctggcct tgaagactct gaaacggact tgtcaaacag tcaccatgca
    63901 actgagtctt tatctcagga caagaaacac gcaggaaagg ttggaaaaat gaaattaaaa
    63961 caattacctc tggaatacca aaaggcaatt ccagttctga aaaaattaga gaatgcagga
    64021 tatgaagctt attttgtagg tggaagtgtt cgtgatatct tgctgaacca gccaatccat
    64081 gatgtggata tcgcaacaag cgcatttcca gaagaaatca aacagctttt tccaaaaacg
    64141 atagatattg ggatcgaaca tggaactgtg ttggtattag aaaatgatga acaatatgag
    64201 atcaccacat ttcggacgga atcaacttat caggactacc gtagaccaga tcatgtcgaa
    64261 ttcgttcgtt cgttggcaga agatttgaaa agaagagatt ttacgatcaa tgcgtttgct
    64321 ttgaaagaag atggagaaat catcgatttg ttcgatggtc tgcaagatct agaagaacag
    64381 atcttgcgag ctgtaggcaa tcctcatgag cggttccatg aagatgcctt acgaatgatg
    64441 cgcgggttgc gttttgtcag tcaactaggg ttcaaattag aggaagaaac cttctacgcc
    64501 atcaaagaaa accacgagct attaggtaaa atatctgtag aacgtataaa tgtggaattc
    64561 atcaagatgc tcttgggaaa tgaacgggcc gcgggaatcc atgcatttat tgaaacagag
    64621 tgctacattt gctgtcccgg tttgaaagaa gaaggcgaag cacttttacg ttttgctgaa
    64681 ttaccatccg tcccattgaa agaagagagc caagcatggg cattattgat cagccaactg
    64741 gatctaaaag aaaatgagat tcgttccttt ttgaaatcgt ggaagtgttc taaccaaatg
    64801 attaaagacg ttcaagcact tgtccaagga ctacgacaac gagaaactgg agctttggaa
    64861 ccattcgaat tgtacttctt aggcaaaaaa catgcactgc aagtagaaga attgatgatc
    64921 tattttgacg aaacacctca gatggatgcc gtaggagaat cctatgatcg tttacctatc
    64981 aagtcattaa gcgaattagc agtagatggt aaaatcttgc tagaagaaac tggaaaaaaa
    65041 cctggtaagt gggttagtga agctttgcaa ttagctgaaa aagccgtcgt agaacaaaga
    65101 ataaaaaatg ataaaaaaca ggttttggat tttttatcga aagaaaaatt gatttaaaaa
    65161 acactagact gtatctgctc agctttgttg gctacttaaa gtgggcagat acgtcattag
    65221 aagaaaaaac ataagatgtg accacttaca taaatttgtg ctaaactgag gtagtacaag
    65281 aataaattac atcataaagg agtcttttta atgagtaaag aaatgacagc gctaaaattt
    65341 tattttagaa atggagaaac ctggacgatc aaccgccgtc atatcggcga tctttggatc
    65401 aaacaaatca caacaagttt tggacgaatc aatggcagtg aatttgttga aatccatccg
    65461 tgtgctggat ttaaaatcga aatcttccat gaaggggacg cagttgcgac acatgatatc
    65521 aacctaggcg gactggaaat gggcatgttt aatcgcgcat tgaaatacga agatatcgag
    65581 cgaatggaaa tcctttaccg aaatggcaca cctgatcttg tgtacttccc atatctagat
    65641 aaaggaacag aaggattaga caatcaatat caatcaacaa aaatcagcga aaaaacaggt
    65701 aacttgtata tcgtgatcaa tccagatcaa cgtgtagaag atgtatacgg ggaatttttc
    65761 gaataaatcg atttttacgc aaaaatgagg ctgtgaaaga gatgtgtctt attactactg
    65821 ataggctgtc tcttccacac cgtttattca gaataaggga ctgtgacaag atttttgtcg
    65881 cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga aagtaaacat
    65941 ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata ctatttggaa
    66001 tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg atgaaacaat
    66061 gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg tataggagat
    66121 ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc gctatggcgc
    66181 cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa atatattgat
    66241 gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa aacgtgtaca
    66301 gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa ttttaaagaa
    66361 aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat ggacgatgga
    66421 atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca tagctagccg
    66481 cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg tattaggtct
    66541 gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta tgattattgc
    66601 accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca aaaatttcgg
    66661 gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg taggtgcgac
    66721 gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg gagcagcgtt
    66781 aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata tccctaaaaa
    66841 ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg ttactgcctt
    66901 ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg cggggatgag
    66961 tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct ggttcaaaca
    67021 aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt atctgctgat
    67081 cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg tatctggaat
    67141 cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa tctctgtgtt
    67201 tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt ttacactgaa
    67261 tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc cagtatgggg
    67321 agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct ctgtcatgct
    67381 ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg gcagtaaaaa
    67441 gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa agggaacagt
    67501 cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt tttaccagcg
    67561 gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca tagggatcat
    67621 tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga atgctttgat
    67681 gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg atcgtaatac
    67741 aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga tacgtgatct
    67801 gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac aagcactgat
    67861 tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc tttcttctaa
    67921 tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca caagccagat
    67981 tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa tcgttctcca
    68041 tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta gtgatgaaga
    68101 tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg aaagtttaga
    68161 taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc aacgcaaact
    68221 tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc agcaagatag
    68281 tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca ttgatgaata
    68341 cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga atatcaattt
    68401 gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat ttgcgtttcg
    68461 agcaaagtca aaaaaaacga gtccaataaa at
//
LOCUS       DAIGTA010000007        67363 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.007, whole genome shotgun sequence.
ACCESSION   DAIGTA010000007 DAIGTA010000000
VERSION     DAIGTA010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.007"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(7..1269)
                     /locus_tag="NOB43_000456"
     CDS             complement(7..1269)
                     /locus_tag="NOB43_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981353.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            complement(1262..2161)
                     /locus_tag="NOB43_000457"
     CDS             complement(1262..2161)
                     /locus_tag="NOB43_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981354.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            complement(2306..4084)
                     /gene="uvrC"
                     /locus_tag="NOB43_000458"
     CDS             complement(2306..4084)
                     /gene="uvrC"
                     /locus_tag="NOB43_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCI0981355.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            complement(4266..4580)
                     /gene="trxA"
                     /locus_tag="NOB43_000459"
     CDS             complement(4266..4580)
                     /gene="trxA"
                     /locus_tag="NOB43_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCI0981356.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            complement(4667..7027)
                     /locus_tag="NOB43_000460"
     CDS             complement(4667..7027)
                     /locus_tag="NOB43_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCI0981357.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            complement(7159..7689)
                     /locus_tag="NOB43_000461"
     CDS             complement(7159..7689)
                     /locus_tag="NOB43_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HCI0981358.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELW"
     gene            complement(7747..8184)
                     /gene="zapA"
                     /locus_tag="NOB43_000462"
     CDS             complement(7747..8184)
                     /gene="zapA"
                     /locus_tag="NOB43_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCI0981359.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            8386..9303
                     /locus_tag="NOB43_000463"
     CDS             8386..9303
                     /locus_tag="NOB43_000463"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HCI0981360.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            complement(9559..10470)
                     /locus_tag="NOB43_000464"
     CDS             complement(9559..10470)
                     /locus_tag="NOB43_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI0981361.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(10873..11451)
                     /locus_tag="NOB43_000465"
     CDS             complement(10873..11451)
                     /locus_tag="NOB43_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0981362.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            complement(11471..12139)
                     /locus_tag="NOB43_000466"
     CDS             complement(11471..12139)
                     /locus_tag="NOB43_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981363.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            complement(12154..13224)
                     /locus_tag="NOB43_000467"
     CDS             complement(12154..13224)
                     /locus_tag="NOB43_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981364.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            complement(13395..14759)
                     /locus_tag="NOB43_000468"
     CDS             complement(13395..14759)
                     /locus_tag="NOB43_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0981365.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLFEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(14756..16315)
                     /locus_tag="NOB43_000469"
     CDS             complement(14756..16315)
                     /locus_tag="NOB43_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0981366.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(16371..18851)
                     /locus_tag="NOB43_000470"
                     /pseudo
     CDS             complement(16371..18851)
                     /locus_tag="NOB43_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18835..19170)
                     /locus_tag="NOB43_000471"
     CDS             complement(18835..19170)
                     /locus_tag="NOB43_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981367.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(19184..20218)
                     /locus_tag="NOB43_000472"
     CDS             complement(19184..20218)
                     /locus_tag="NOB43_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI0981368.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(20308..20988)
                     /locus_tag="NOB43_000473"
     CDS             complement(20308..20988)
                     /locus_tag="NOB43_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0981369.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(21272..22375)
                     /locus_tag="NOB43_000474"
     CDS             complement(21272..22375)
                     /locus_tag="NOB43_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI0981370.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(23004..23474)
                     /locus_tag="NOB43_000475"
     CDS             complement(23004..23474)
                     /locus_tag="NOB43_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HCI0981371.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            23804..25444
                     /locus_tag="NOB43_000476"
     CDS             23804..25444
                     /locus_tag="NOB43_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCI0981372.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            25598..26920
                     /locus_tag="NOB43_000477"
     CDS             25598..26920
                     /locus_tag="NOB43_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HCI0981373.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(26988..27422)
                     /locus_tag="NOB43_000478"
     CDS             complement(26988..27422)
                     /locus_tag="NOB43_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0981374.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(27487..28323)
                     /locus_tag="NOB43_000479"
     CDS             complement(27487..28323)
                     /locus_tag="NOB43_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCI0981375.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(29065..29691)
                     /locus_tag="NOB43_000480"
     CDS             complement(29065..29691)
                     /locus_tag="NOB43_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981376.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(29986..30321)
                     /locus_tag="NOB43_000481"
     CDS             complement(29986..30321)
                     /locus_tag="NOB43_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCI0981377.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(30308..30592)
                     /locus_tag="NOB43_000482"
     CDS             complement(30308..30592)
                     /locus_tag="NOB43_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HCI0981378.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(30648..32171)
                     /locus_tag="NOB43_000483"
     CDS             complement(30648..32171)
                     /locus_tag="NOB43_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI0981379.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(32164..33339)
                     /locus_tag="NOB43_000484"
     CDS             complement(32164..33339)
                     /locus_tag="NOB43_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI0981380.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(33343..33528)
                     /locus_tag="NOB43_000485"
     CDS             complement(33343..33528)
                     /locus_tag="NOB43_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981381.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(33494..35188)
                     /locus_tag="NOB43_000486"
     CDS             complement(33494..35188)
                     /locus_tag="NOB43_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCI0981382.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(35185..35658)
                     /locus_tag="NOB43_000487"
     CDS             complement(35185..35658)
                     /locus_tag="NOB43_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HCI0981383.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(35727..35882)
                     /locus_tag="NOB43_000488"
     CDS             complement(35727..35882)
                     /locus_tag="NOB43_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HCI0981384.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(36016..36396)
                     /locus_tag="NOB43_000489"
     CDS             complement(36016..36396)
                     /locus_tag="NOB43_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCI0981385.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(36400..36615)
                     /locus_tag="NOB43_000490"
     CDS             complement(36400..36615)
                     /locus_tag="NOB43_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981386.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(36618..37025)
                     /locus_tag="NOB43_000491"
     CDS             complement(36618..37025)
                     /locus_tag="NOB43_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HCI0981387.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(37291..38766)
                     /locus_tag="NOB43_000492"
     CDS             complement(37291..38766)
                     /locus_tag="NOB43_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HCI0981388.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGESTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(38756..39604)
                     /locus_tag="NOB43_000493"
     CDS             complement(38756..39604)
                     /locus_tag="NOB43_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HCI0981389.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(39641..40003)
                     /locus_tag="NOB43_000494"
     CDS             complement(39641..40003)
                     /locus_tag="NOB43_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981390.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(40004..40162)
                     /locus_tag="NOB43_000495"
     CDS             complement(40004..40162)
                     /locus_tag="NOB43_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981391.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            complement(40303..40927)
                     /locus_tag="NOB43_000496"
                     /pseudo
     CDS             complement(40303..40927)
                     /locus_tag="NOB43_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(40924..41235)
                     /locus_tag="NOB43_000497"
     CDS             complement(40924..41235)
                     /locus_tag="NOB43_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981392.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(41279..41572)
                     /locus_tag="NOB43_000498"
     CDS             complement(41279..41572)
                     /locus_tag="NOB43_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981393.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            41766..42413
                     /locus_tag="NOB43_000499"
     CDS             41766..42413
                     /locus_tag="NOB43_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0981394.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            42474..43619
                     /locus_tag="NOB43_000500"
     CDS             42474..43619
                     /locus_tag="NOB43_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0981395.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(43700..44005)
                     /locus_tag="NOB43_000501"
     CDS             complement(43700..44005)
                     /locus_tag="NOB43_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HCI0981396.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(44030..44461)
                     /gene="ruvX"
                     /locus_tag="NOB43_000502"
     CDS             complement(44030..44461)
                     /gene="ruvX"
                     /locus_tag="NOB43_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCI0981397.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(44458..44724)
                     /locus_tag="NOB43_000503"
     CDS             complement(44458..44724)
                     /locus_tag="NOB43_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HCI0981398.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(44979..45704)
                     /locus_tag="NOB43_000504"
     CDS             complement(44979..45704)
                     /locus_tag="NOB43_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCI0981399.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(46065..46135)
                     /locus_tag="NOB43_000505"
     tRNA            complement(46065..46135)
                     /locus_tag="NOB43_000505"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46101..46103),aa:Gly,seq:ccc)
     gene            46252..47004
                     /locus_tag="NOB43_000506"
     CDS             46252..47004
                     /locus_tag="NOB43_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI0981400.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            47020..47499
                     /locus_tag="NOB43_000507"
     CDS             47020..47499
                     /locus_tag="NOB43_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI0981401.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(47750..49330)
                     /locus_tag="NOB43_000508"
     CDS             complement(47750..49330)
                     /locus_tag="NOB43_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HCI0981402.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(49323..50066)
                     /locus_tag="NOB43_000509"
     CDS             complement(49323..50066)
                     /locus_tag="NOB43_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981403.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(50242..51018)
                     /locus_tag="NOB43_000510"
     CDS             complement(50242..51018)
                     /locus_tag="NOB43_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0981404.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(51266..52102)
                     /locus_tag="NOB43_000511"
     CDS             complement(51266..52102)
                     /locus_tag="NOB43_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HCI0981405.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(52113..53042)
                     /locus_tag="NOB43_000512"
     CDS             complement(52113..53042)
                     /locus_tag="NOB43_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCI0981406.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            53234..53587
                     /locus_tag="NOB43_000513"
     CDS             53234..53587
                     /locus_tag="NOB43_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI0981407.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(53661..54317)
                     /locus_tag="NOB43_000514"
     CDS             complement(53661..54317)
                     /locus_tag="NOB43_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI0981408.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            54543..56477
                     /locus_tag="NOB43_000515"
     CDS             54543..56477
                     /locus_tag="NOB43_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0981409.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(56563..57786)
                     /locus_tag="NOB43_000516"
     CDS             complement(56563..57786)
                     /locus_tag="NOB43_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0981410.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(57780..59678)
                     /locus_tag="NOB43_000517"
     CDS             complement(57780..59678)
                     /locus_tag="NOB43_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HCI0981411.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(59672..60790)
                     /locus_tag="NOB43_000518"
     CDS             complement(59672..60790)
                     /locus_tag="NOB43_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0981412.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(60873..61706)
                     /locus_tag="NOB43_000519"
     CDS             complement(60873..61706)
                     /locus_tag="NOB43_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0981413.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(61699..62616)
                     /locus_tag="NOB43_000520"
     CDS             complement(61699..62616)
                     /locus_tag="NOB43_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0981414.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(62843..63967)
                     /locus_tag="NOB43_000521"
     CDS             complement(62843..63967)
                     /locus_tag="NOB43_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0981415.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            64150..65058
                     /locus_tag="NOB43_000522"
     CDS             64150..65058
                     /locus_tag="NOB43_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0981416.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            65199..66812
                     /locus_tag="NOB43_000523"
     CDS             65199..66812
                     /locus_tag="NOB43_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0981417.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKKPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        19981 a        13674 c        11306 g        22402 t
ORIGIN      
        1 tatattttat gctttttttc gttcatttct cataattgaa atcgattgtt tcaatgaact
       61 ccataatccg ccttcgctat acacgagtac attcgatttg tacatgtttg cagacaagat
      121 catcaataag aatgttacgg ctacaagtac caacaaggaa atcaatgctc cacccatacc
      181 gactgtctca tttgctaagc gaaccggcat aatatatgaa gataagaatg gaatatacga
      241 agtgatccga ataacgatat tgtttggatc tgaagctcct agtatcaatc caagcatata
      301 tccgcctaga gatagataag tcactggcaa aattgctttt gctgtatctt ctgctttgtt
      361 gaccaaagag ccacataaag ctgctaaaac agaaaaaatc aaaatgccaa agatcatgaa
      421 tagaagagaa taccacaaga atggtccaat caagttatcc aatgagatac cgtctaatat
      481 atttttgacc atttccatat ctttgaattg actgtatcct ataccaaaaa taataccgta
      541 taatgccatt tgcgttaatg caacaagtaa aacacctgtt agttttccgt aaaaatgctt
      601 ttgtgcagtc gtactggaca ggatcacttc catgatccgc gtgccttttt cagaagcgat
      661 ctcttgtgca atgatctgcg catacgtcaa aataataatg aacaagacaa tcgttgctac
      721 ataacttacg acatattgga ctgtcgagtt atcttctcca actgtcattt ttccttttga
      781 atcaaaattg actttttgtc gagtcaaact tgcttgttgg ctcaagctag ctacttcttc
      841 tggtgaaatg cctaattgac ttgctcgaag catcgattgc aagccagtca gttgttgttg
      901 tatcagtagt tgtgtacttt gtcctaatga attttcgcta taaagcatcc catttatctt
      961 atcattctca gttgagacta ctaaatacgc atcgattttt tcttccgaaa gctctttttg
     1021 tgctttttct tcagaatcaa ctgctttgaa ctcaaaatca tctgttttga cttggctcat
     1081 ttgctgactg atttgctcat tatcagccaa tacgccgatt ttattgacat cactattttg
     1141 ttgagcaaag tttcctgcta cataaatgat acccagcatg ataaaaggga ctaatatcat
     1201 gatcaagaaa gaaatcgact taacattttt taaatagaca tctttggtaa taatccaaaa
     1261 cttacgcatc gatttcacct gctttcaatt tgaaaatctc ttccaaagtt ggcggttgct
     1321 ggttaaacat aggaatgtag ccgaactgag tcgcacgagt aaagatttct ttcccagctt
     1381 caggatcttc taaggtaatc tctaacgtat tgtcttcatg aaggatcact tttttcacgc
     1441 cttcgatttc ttctacttcc tgttggctta aaccagattc caagaataac ttcgtacggc
     1501 caaatgattc acgaatctca tgtacttttc cattcaaaac catttttccg tttcgcaaca
     1561 tgatcaaatg atcgcagatt ttttctacat tatccatatt gtggctagaa aaaatgacac
     1621 atgaaccatg ttttttcaat tccaatattc catcttttag caattcagca tttaccggat
     1681 ctaacccgct gaatggctca tccaaaatga tcaatttagg ttcatggatt aacgtggcga
     1741 tcagctggac tttttgctga tttcctttag acaaagattt tactttatcc gtctttttcc
     1801 cttttacctg aaatttttcc atccaaaaat cgatttttgg ttcaatctct tttcttgatt
     1861 tccctctaag ttctgcaaaa taaagcagtt ggtcttgaat cgttactttc ggataaagtc
     1921 cccgttcctc cggaagataa ccgatgacat cataatcttt ctccccaaga tgatggccat
     1981 tccataacac ttctccttgg tcttgtgtca aaaaatccaa gatcaaacga aaagtcgttg
     2041 tcttcccagc cccgttttgg ccaattagcc ccatgatttt tccatcgggg atttggaaag
     2101 agacatgatc gacagctgtg tagttcccaa aagttttaac aagatccttg acttctaaca
     2161 tttcttcact ccttcttcaa gaaatcacat atatccttag acaccagacg taagcgattt
     2221 attatttacc aacaaaacgt aaacgctctt tttgttgtac ataaaatgat aggacacttt
     2281 actttctttg taaagtgccc tttcctcatt cctgatgtaa tttatcaaat acgttttgtg
     2341 cgacattttt cggcagtccg atttcttgta attcttctgt cgtggctgct gtgatatttt
     2401 tcaacgattt gaactcttta agcagcattt tttttcgttt tggtcctaac ccttcaattt
     2461 catctaatcg ggaagcaaaa ctgtttttac tgcgtagctg ccgatggaaa gtgattgcga
     2521 atcgatggac ttcatcttgg attcgctgga gtaagaaaaa ctctggtgaa tttcgctcaa
     2581 gcggtactac agccaaatct ataccgaata gcaactcatt tgttttatgt ttatcgtttt
     2641 ttgccatgcc agcaatagga atatcgattc ctaattgatt ttctaagaca tcttttgcca
     2701 catctacttg tccttttcct ccatcgatca agatcaaatc aggtaaaggc aacccttcgc
     2761 gaatcactcg tgaatatctg cgatagatga cttctctcat tgatgcataa tcatccggtc
     2821 cgttgactgt ttttatttta tatttccgat attcttttct tgccggtttt ccatcaatga
     2881 atacgaccat cgcagccaca ggattcgtcc ccatgatatt agagttatca aaagactcga
     2941 tacgtattgg ggtcgggata ttcatcgcgt ttcctaaacg ttcaactgct ccgatcgtcc
     3001 gttcctgttt tctggcaatc agatcaaacc gttcattcaa agcaactgag gcattcttat
     3061 tcgccaattc aactaatttt ttcttttctc ctcgttttgg ttgcagcact ttcgtagcta
     3121 acaaagcttc tacactgggc ttgtcgatcg tatcaggaat caagacttct ttaggaatga
     3181 aatgctcatt ttcctgataa aactgaccga ggtaagtcaa gaaatcttct tctgcttcgt
     3241 tatagaaagg aaacattgaa acatctcgtt caattagctt tccttgtctt acgaaaaaca
     3301 cttggacaca catccatcct ttgtcaatcg cataaccaaa tacatctcga tccagtaaat
     3361 cagtatttgt cattttttgg cgagtcatga ttgtctcaat ggcacggatc tggtctcggt
     3421 attctgcagc tttttcaaac tccatgtttt cagcagcttt ttccattttc tgatggatct
     3481 ctgactcgat tttttcgtgt cctccgttta aaaacttttt cacttcatca acgattttcg
     3541 tatagacttt cggatctacg tcgaaataat aaggacacag acattgtccc aaatgatagt
     3601 aaagacaagg ctccttcgtc tgactaggtt tgcattttct cagaggaaat aatcgatcga
     3661 ggatcttctt tgtctcattc gccgcaccga catcgggata tggtccaaaa tacagtgctt
     3721 tgtcttttag tactttacga gtaatcacca aacggggata tttttcattc gttatcttaa
     3781 ggaaaggata ggttttatca tcctttaaca taatgttgta tttaggatca tttttcttta
     3841 tcagattgat ctctaagagc aatgcttcga tattcgattc tgtaacgatg tattcaaagt
     3901 cttcgatttc actaacaagc cgttccgttt tcgtattatg gctgccagta aaatatgagc
     3961 ggacacgatt ttttaatatt ttggctttgc cgacataaat gatcgttcca tttttatctt
     4021 tcatcaagta acagccgggc tgatcaggaa gtaaagctaa tttgtttttg attcgttcgt
     4081 tcatctggta ctccccttca tattcaatta aagttattat agcatgtctg tcaaaaaaac
     4141 aatccagcct gacaacgtaa ttatactcaa aaaatattaa tttgaataac cttaactcaa
     4201 ccgcaaaaaa accgaggacg gaactggatt cagtcccacc ctcagcttat ttttgctgta
     4261 agtttttata aatattgatc gatcatttga cgtagttgtt cttttgaatg aacaccaaca
     4321 gctttttcta ctacttgacc atcttttttc aacattaatg ttggaatgct catgataccg
     4381 aattgttgag gagtttctgg attttcatcc acatccattt tagcaattct gaattcttct
     4441 tcatcatatt cttgttccaa ctgatccaaa atcggtgctt gcatacgaca tggaccacac
     4501 caagttgccc aaaaatcaat caatacaagt cctttatctg tttcttcatt aaatgtctta
     4561 tctgtaatta cttgtgacat atcaaagacc tccattttta aaatctatga ttagtatagc
     4621 atttctatac ttggatagcg aaccatctgc ttacctttag taagctttac ttaaatttaa
     4681 caattgtcgc accatttccg ccttggtttg ccggtgcaaa ctcaaagctt ttgacgctcc
     4741 gatggttttt aagataatca gtaattccct tgcgaagtgc gcctgttcct tttccgtgga
     4801 caatagtcac ttgaggataa ccagctagaa tggcagaatc caaatattga tctacctcac
     4861 ttagcgcttc ttcgtatcgt tttcctcgaa ggtccaattg attcggcacg tgactactag
     4921 attcagatcg tacagcatgg ataactcgtt gtgtcggctc tttttgagga gcaacaggcg
     4981 tcagctcgtc ttcggacaca ttcattttta atataccgat ttctacttgc cactgattcc
     5041 cgtttttacg taaaagcgtc cctctttggc cgtaagtcgt aaccaacact tcgtctcccg
     5101 gtttcaacgt tttttgttct ttcgccttct tcaatacttt atttttcttc aaagtttctt
     5161 cttgatgtag atttgctaat tgggtctttg catcgatcaa ctgatgctct ttcacatttc
     5221 cttgcccaat ctgctgttgc attttacgaa tatcagcaat gattttttct gctttttctt
     5281 ccgcctctga cacgacttcg tttgcttttt tctttgcttt ttccatttct ttttcacgtt
     5341 cttcaaagaa atagctgtaa gcttctttca aatcatcgtg aagttcttgt gcctcagaaa
     5401 caaaatgacg catttccaga tattcggtct ctgccatttt ccggcgattc tctaaatctg
     5461 tgatcatttc gtttaaatct tggctctcat cattcatcaa ctgcttcgct tcatcaataa
     5521 cttctgtatc aagacctaat cggctagaga tttcaaacgc attgcttcgt ccaggaacgc
     5581 caatcagcaa acgatacgtt ggacttagtg tatccacatc gaactccatg ctggcattaa
     5641 tcgtatttgc ccgattgtat ccataaactt tcaattcagg ataatgcgtt gttgccatca
     5701 cataagcaga ctttttacca agatcatcta agattgcgat tgctagagca gcaccttctt
     5761 gcggatctgt tcctgcaccg agctcgtcaa ataataccag acttttttca ttgacttttg
     5821 ataaaatatc tacagtgttc gtcatatgag aagaaaaggt cgatagactt tgctcaatcg
     5881 actgttcgtc tcctatatcc gcaaatactt cctcaaaaat accgatttga ctttcttcac
     5941 ctgcaggaat cggtaatcct gcttgcccca tcagttgtaa cagacctaaa gtcttcaacg
     6001 tgatcgtttt cccacctgtg ttaggtcctg taatgacgat ggcttgatag tcttttccga
     6061 ttgtgatgtc attagaaact actttttcct gatcgatcag tggatgtctt gcttgtttca
     6121 agacgacatg attgtcttca ctgattcccg gcacgatggc ttttacttct ttaccaaatc
     6181 gtgcttttgc attcatcaga tccattttac caatcacata agcattgtgg atgatttctt
     6241 gacgatgggg aacaagttca gcagaaagtt cacttaaaat acgttgaatc tcatttcgtt
     6301 cagcgatttg gtattgacgc aaacgattat tcaaatccac cacttgtttt ggttcaataa
     6361 ataaagtctg tcctgaagca ctttgatcgt ggactacacc gccaaataca ccgcggtatt
     6421 cttgtttgac tgggataacg tagcggtcat ttcgcatggt gatgatcgca tcacttaaat
     6481 actttgcatt tttcccacgg acgatcccat ctaactgttc acgaacagct tgttcacttc
     6541 gccgaatgtt ctgtcttatg ctctttaact caggagaagc gtcatcagtc acgcgtccgt
     6601 cttcatcgat tgcttccttt aaacggcggc tcaaaacagg gatcgtgact aactgatctg
     6661 cccacatata caaacgtgca aattcgattt cactgtcaga aagatcatca atgaaacgat
     6721 tcaattcgct tgtcgtagac aatactctgg aaacttgtgc aagctccact ccattcaagt
     6781 ctgctccgat ctcgatccgt ttcatatggg gacggatatt ttcaagttta ggtataggga
     6841 tcccgcctcg cagacgttgc actttcaatc catcctcagt ttcttgaagc cagtttgtga
     6901 tcgtttgttt ctcactcact ggtaccaatt ctgccagttc ttcttttcct tgtgcagtca
     6961 ctacaaattg tctgaccatc tgtttgactt tttcaaattc caatgtttca aggattcggt
     7021 tattcatttt atcaccttat ctttcactat gaaaaaagag ctgtgccgga catacgctac
     7081 gcagccttct taaataaact actctgtaca aaaaacgaaa tattttccag cactattttc
     7141 cttaattcaa aatattcgtt accaaagctc atacatcttg ttggtaagaa atggcgttct
     7201 ctcaacgata aaacgagcga aactatgctc gccgaattga ttttggacca catctaatgg
     7261 aacaaaggca agtaactgca aaatcaaaaa tatagtaacg taagccatga ttagtgacag
     7321 gatgcctcct gcaatccagt ctacctgtct caagatcggc acatacgtca atccatggac
     7381 aaaaaccccc acaaatcggg taagcagcca gccaattagc aaaataatca gaaaagcagt
     7441 tcctgcataa aaagcttcat ctaggtgaaa agcaaatacc tgatcaaaaa atgctaactt
     7501 tgatgttggg gtgacagctg ggtatggaat gtataattcc aaatgacttg ctaatggttt
     7561 gtaaaaatgc tgggcagcaa taaatgacaa tacatatcca atcgcgaata tgatttgcaa
     7621 agcaaacccg cgacgtgctc cagaaaaaaa cgcaattagc aataaaaata aaatcagcaa
     7681 actcagcatg ctacgttcct ttctcttcta acttttttaa atttttctta ttttgataaa
     7741 aggatcttaa ttagaagatt tttgtttaat ttgtcctttt cgtttctcgt ttaaaatctg
     7801 ttgtgcttcc acatgatttt taatggtatg atctgcttga ccattttctt tcaatacttc
     7861 ccgagcttcg ttctcgattg cttcaatgcg tttcacacga ttttcaagct ctgtaaattt
     7921 gatcattttt ttctttaatt ctgctgtttc ttcttccagc tccaagattc tttcttgttt
     7981 cttcaattga tccgaaagcg cattgacagc catcaagatt gctgcttgtt cattatccat
     8041 ttgtggtgat aattgtttca attctgctaa ctgttcattg atcagcttcg ttacgatatc
     8101 catatgatgc ttggtttccc gtccgataat agtatatgtt tggttggcaa tcactgcttt
     8161 gtagcgtgtt ttttcgtgcg ccatacgaat catttcctcc tatttgatga aagttttatt
     8221 tagtgtacca tgaagttggt tctttcaccg ttctccacaa atatttttca catacttaac
     8281 tattatatga taaactttaa aaaaatgcta tgtctcgcaa tctcttagaa aacgaaaagt
     8341 cgtgagttgc ggtatagttt tatgtataaa aacgaggaga attttatgag caacgtcatt
     8401 atcaaagcaa caaacgacca acttagtcaa atgaaagcat actatcgctc ttatttgtta
     8461 aataaacaga ttccttatac tagctttgct gcaaaaaaag acgggacgac cattaccgct
     8521 tatacatccg gaaaagtgat gtttcaaggt acgaatgcag caatagaagc tgataaatgg
     8581 ggggaggcac aggataaaca agccaagcca gcaaaaacag cctcttcttt gccaaaaaat
     8641 atcagtcaat tatccgtttt aggtagtgat gaggtcggaa atggcagcta ttttggtccg
     8701 ctaacagtat gtgctgctta tgtgaaacgt gatcagcttg cagaattacg taaacttggt
     8761 gttagagatt caaaagagtt aaaagatagc caaatcatcc agcttgctga catcttaaaa
     8821 aaaaccatcc cctataaact gcttgtctta tctccagaaa aatacaatga gatccaacca
     8881 aaatacaatg ccgttcggat gaaagtcgct ttgcacaatc aagcgatcca tttgctgcta
     8941 aaaaaaatcg agccagaaaa accagaagcg attttgatcg atcagtttac gccggaagca
     9001 aattttaaaa aatatgcgcg tttagaaaaa aatcaattac aagaaaaact gtacttcgtt
     9061 actaaaggag aacaatatca tttagctgtt gctgctgctt ctatcatcag tcgtgccagc
     9121 tttttggaag agttacacaa agcatcagct gaagctggaa tcacccttcc atcaggagct
     9181 ggaacgaaat ctgaccaagt agcggcaaaa ctattggaga aaggcggcat gcctatgctt
     9241 gaaaaatatg ccaaacttca ttttgccaat acagaaaaag ctttgaagct gctaaaaaaa
     9301 taatggaact gtgacaaaag tcatgtcaca gtcccttgtt ccgaataaac ggtgttctca
     9361 tgccaactcc tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa
     9421 ttgctccttg tgacgcggag ttaaacggca ggctcacaac ctcttcctta aacggtgttc
     9481 aaaagcttgc atctgcgata ataagcccgg ccaaacgaaa aatatgagga gctatttttg
     9541 tttggctggg cttatttatt actgaaaata agtggtcaat gcttgtgtca aacttgcagc
     9601 aatctgctgc tgataactgt ctgttactaa ttcctttaaa tcactatcat tattcatata
     9661 acccatctcg attaaaatag aaggttgaag attttctcga agaacttgat agttcccagt
     9721 ggagattcct cttgaatcca gaggcagatc agtgaaggag tcagcaattg tctgtgctaa
     9781 tgtttcctct tgtccatagt aataatatgt cgtgattcca gttgcttcat tcgcatattc
     9841 cgtagagtct gcgtgtaaac tgataaagac atctgccttt ttttcttcac tgtagtcgca
     9901 tatatctcca agctgtacta attcatctgt agtatgggtc aaataaaccg ttgctccagc
     9961 atcctctagc gcctttttta cttttatggc tgtacttaat gttatatctt tttcttctgt
    10021 ttgttcatca ttgcttaatg ccccagtatc atttccgcca tgcccaggat ctaatacaat
    10081 cactgcatca gatagctctt ccggttttgt ttgtatattc tttgtgactt tggttccatc
    10141 ttcgagggct aaatatccag tatagccatc atttgtcttg atctgataag cattttttgt
    10201 ttcagaaaga aactccgcca gctctccgcc gtttatagtt gcaagtgggg tagttagcga
    10261 gtcatctgta tatagtgtac ggtcattttt tccgattttg attaatgtct cttgttctgt
    10321 atcatcaaat gattcctttg tctttgtaac cgtactgttc gtactgctga ccgtttgtcc
    10381 aactatcttt ttttgaccaa aaacatctat ttgaaaacag ataataatga taatgattgc
    10441 aaatacaaaa gctccaatta tttttttcat tcttgactct cacctcgtag atccagacta
    10501 agggtcaaaa cttaaaatca gcttaagtac gcaaaaaagg ggctgtaaaa gatataaccg
    10561 tagaaaataa cattactgct aaaatgattt ttttcatttt tggcatatcc tgaaatctcc
    10621 ttttgactat tcgtggtgat tcatctaccc aataaatagt ttccttcatt ctacaaacaa
    10681 ttaatttctt cgttattaaa ttaaaacact tcctggaaca ccgacataat aaataaaaat
    10741 ataccctgat aatcatgaga gaataacaaa tttgtattta tgaaaaacta cctatataaa
    10801 aaaaacaaga tataacgatc ttcgtcatat cttgcttctt cacctaacta tttttctccc
    10861 tatataacag ctttacgctt ctcctaatac accattcaaa tataaatcga tcaattgcgc
    10921 cacatttagc ggttcttcca caggtctttt cgaccgagtg atgtaaggtg ctaacactaa
    10981 gaaaaaatgc cttgctgcga tttcttttga aatcccattt cttagcacag attggtttgc
    11041 tgaaaagatt tcttcaaaag gttcacgata atttttcttc catagaaaga aaagatgatc
    11101 tcttgtttcc tttgaaagat tgctttcaag atcgtgaagc atcagaaaca aatcgaccag
    11161 atgtgtctca atcaaaaact gcgccatttt tgtcaaggtt acttgaaatc ccgtttcgct
    11221 tgtttgaacg atttctctca aagcttttcc aacatctttt aagtggtttt ctaaaactgc
    11281 cgtatatagt ttttctttat caccgaaata atgatagaga ttgggttggg tgatcccaac
    11341 tttttgtgcg atctctcttg ttgaagtgcc gagatatccc ttggacataa acaagtcagt
    11401 cgcttctttc aaaatttttt gctgtgtatc tttgttgtat cgatggacca tttttccacc
    11461 tgctttttgg ttattctttt tctttcaata caccatcttc catcataaat attctatcgc
    11521 atttgtcaat cagccgtgta tcgtgagtaa ccatgatcgt tgctttattt ttgtcttttg
    11581 attcttttgc caagatatcg actacttctc gtgccttttc tgaatccaaa ctagcagttg
    11641 gttcatctgc tagaataatg gacggatcat tgtacaatgc acgagcgatt gcgacccttt
    11701 gccgttctcc accagatagt tcttctggat acttgttgat caacttatcc acgccaagct
    11761 gctcaaataa ttcttttgct tctttttgac gatgttcatg tttgatctta tctactaata
    11821 ataactgctt ttttactgtc agaaaaggaa ccagattgga agcttgcaaa ataaagccaa
    11881 tttctttaaa acgtagttta acgcgttcac tttctttttg attactgaat tcttgatcat
    11941 tgataaatac agagccactg ctaggcgtct gcaatccgcc tgccaaagtc aaaaaagtac
    12001 ttttacctga accagaagga ccgatgattg caacaaattc ccctttatcg atactcatgg
    12061 ttgtttcttt caatgcttta actacttggt cgccatcttg gaaacttttt tctacttctt
    12121 taaattctat tgctttcatg ctcttcctcc ttcttatcca attgccttca acggatcgat
    12181 ttttacgatt gtccgaacag aaaatagtgc gcctaacaca gctactacca gcatcaacaa
    12241 gctaatgacg ccaaaaaaca gccaattgct ttggaatgga accgcatcag gtagaacaag
    12301 ggatgttccc actgttccta atagaccaag aagaatacca acaaatgata aaatgaatgt
    12361 ttgtgccact acagaacgcg caataaatcc tcctgtgatc ccttgtgctt tcattacacc
    12421 aaagatatta atcttttgca tcgtcagtac ataaatgaaa atcccgatca caatagccgc
    12481 aataacgatc aaaaatccga tcataaatcc aaaagtcaat acttgcgcat tatatccagg
    12541 taattcattg atgaatttag aaattttgat ctgttctaaa tcttcaggta aattactgat
    12601 tttacctctg acaactattg cgttaatccg tgcattttca cttgtatctt ctttttcgaa
    12661 gcggatctct tggtaagcat tgatggttgt atagagaact ggtgagacat tgaatttggc
    12721 atgatccgta aagccagtta gtttaaacgt cttgtcacta ccagataact taactgtatc
    12781 tcctacggct agaccatatt cttctttcaa actaatatcg cctactgcct catcatcgtt
    12841 atcaaaagct tttccttcaa caagattggg catgatgaat tgatttttat cgataccgaa
    12901 gaagctaaca ttgatttttc cttcttctgt actgtcttta ctagtcacga ctccaggtgt
    12961 ctgggcaaga tacgccactt tcccaccttc gacttcttct gctatcttct tagtaatcat
    13021 ggacatccct agatttgaat ttgcatcttt cgaaagcaca atcgaatctg cctcccactt
    13081 gtcgactgct gttcgattat cttgagctaa gccataagct aacccagtca aaaaaaatac
    13141 caggtaggcg atcaaaaaca tcacccctgc aactaacgca taacgtaact ttgaatgcat
    13201 aatttcattt aatgctaaaa acatttaact cctcctcctg aaataatcat tttatacaac
    13261 aattttatca cttgataaat ttttggcgaa tattatgctc aaaaaattct tccgctattt
    13321 cattatatga attttttatt ctcgattgat taatatttat tatatcccca cacaataaaa
    13381 gaccgtgata tttctcacag tcttttatct actctattgc tatttgctct cttagctagt
    13441 actttaaaag ctaactcatt gaggtagtga aaacgagagg tgtgttcaaa cagaaatcca
    13501 aaatcctcaa ctgctagctg tggaatcgta gttttgtgtt tcacgatatc cgcaagcagg
    13561 ttcaaatctg ataataagaa ttcttggctt atcagctgtc cgccaattat ttctaatgta
    13621 tccggatggt agatcagctt tgcatttact gttttgtttt cttcatcgta ttgtggaaat
    13681 agatcaaatt ctcctgaaca cgaaccggta ttttgttcca agaatggcgc ttcatcttct
    13741 gtcagcccta cagttcctaa aaagtagtct ataatgactg ctgctgttat cttttgtctg
    13801 aggtcgtaag cggttggctg accactcaaa gttagcgcta ctgctcttgc catatgtaca
    13861 gctcgagtaa ctaaaggtaa aaagagatgc cgtttatttt tgtcaaaact gactgggacg
    13921 atatctccaa tcgcatagat gtccggatca cttgtctgca gatattcatt gactatcaca
    13981 gtctcatcct catacaaagc cactttttct tttaacaatg tcgtattagg acgagtttgg
    14041 gcagaaaaaa tgaccatatc tgcctttatt gcttgagata gaagttgtac ggatactact
    14101 ttctcttctg attttttcca atcgatcaag aattcatttg gataaaaatt gatttgctta
    14161 gtttgcagct gattttgaaa actgttgatc atatccttat cgaaatatct tgataaaaca
    14221 ttcggcatat aatcaactag atgaataatg tatcctttat ttctcaaagc atctgctaat
    14281 tccaatccaa tataaccagc accgaagatc actacttctt ttgcttcttt taaagcggca
    14341 agtacttgct tagattgcac tagattttta taggtgtaga cattttcagc ttcaatttgt
    14401 ttatacaagg tgacaggaga ggaacctgtt gctacgatta atttatcata ggttatggtc
    14461 tcgttttttc cttctttgga tgcgaggatg agctgatgtt tgtctggatc aagttcagtt
    14521 actctccatt cggtgatcag ttttgcccca ctttcttgaa gagtccgcat gttatgggca
    14581 acttcagcta aactacgtat ctttcctttt aaataaaggt tgattccatt tgaaacatag
    14641 cctagtccat ctttatgatc ttcatcgatc agtaaaactt ctgctttcgg ttgaagtttt
    14701 cttagattta gggcagctgt gatgcctgca tgggaagcac caatgatcac gattttcatg
    14761 ttttattcat ccttaaattc aatttttcta aataacattc ttttaaaaat tggttcaaat
    14821 aggggaaatc ataattatat tcgttgctag tgaatacaaa aactttagcg gacttctgtg
    14881 acgggtactc tttcaattgg ctagtcaaaa tgatatcata ctgcttttct ttctcgtatt
    14941 cgactaaatc atatttgatc gtattcagca attgttcctg gatgatttct ttcacgatat
    15001 ccgccattag cctttcataa ggaagatcat aagcaatttg cagacgtaat tctaactgct
    15061 tgatcagcgt ccgcaaaata gatgcatagc gagcaaataa ttcaaagcgg gcattttcct
    15121 cgtctacttc agtaaaatca acaatagcaa atgtttgtct gaccaatctt tcacataaaa
    15181 ccaggaattg tttatcttct acttcagtta accgctgttt taatccttct tggccaaaaa
    15241 tattcatcca tcctctaaaa taggcaaaat gagcgtgatt ttgcatcact gtcaacgcaa
    15301 tcttttgcga aatctcttct ggaaaaacat aaaaagagaa atattcttct atcgattgtt
    15361 taaacgttcg attcaattga gctactacgt cgtctttgta tttttcgctt atcaaaaact
    15421 cctggacatg cgagttatgt gtatctaatg taaagttact gatcatgaaa agataaaaaa
    15481 ccaacgtttc attttgattc caaggaaagg catattgaaa gaagtaacgg gtcaaaaatg
    15541 tatggaggtc caataaaaat tgtgtcgttt gaaacaatcc aacaggaaga ttgctataat
    15601 ctggtttgga ttttttcgta cagcgcattc gcttcttcat aatggaaagc catatttcaa
    15661 atttcaatcg tccttcttct gtaatagtaa aactaaactc tttttgcagc agatctaaaa
    15721 aagtgtttcc tgataaatca ctgtattctt ttttgttttc aagataagga cgtccaaacc
    15781 aaaataattg gaaataaaaa taacaaattt gactttctgg accggtcagc cgcccgcttt
    15841 ttattttcag atgaaactca tttaaagaat catttaattc cttcactctg cgagacaaag
    15901 tagccgaact gatattaagt tccatgacaa gtttctgccg atcaaatgag ccattttcca
    15961 acagataaag aagtatctga tattttgtag aatagcgcaa gtagcaatga taataaacat
    16021 cgactgctgc tatatttcca tgtctgatta ataaaatatt cccttcttgg ataacaattt
    16081 ccaattgttt gatattttcc aagttagctt gtaaataaaa cagatcttct ttcaaggtag
    16141 cccgatcaac tgataagcgg gtaagtacgt tattaacgga aatctctcct ttttcctcta
    16201 ataaaagttg gaaaagtttg atttgccgtt gttcattttt ttcaagcaaa ctgaaaagtt
    16261 ccaagtccac tcctccaagc atttctgatt ttaacagcag aagtttcctt ctcatccttg
    16321 aaaaagagga tctgtgacag ttatcacaga tccatacaaa ttctaatcac ttagctggtt
    16381 ggcccagctg tcagttccca tgtgaccatg ccttgatacg ttgcgccagg ttgagcattc
    16441 gtactgctat ttacctctaa gagtaaacca tcggtatcgg gaaagtcaac gagaacctct
    16501 cctttagctg ttccatcact ctcataaatc aacgtgtttt gaccttgctg aatcaattgt
    16561 tttgatccag aatgattgaa gtataatttt gttccgctta attcttgacc ttgatcattc
    16621 ttaaataaag aagtcaatgt ccctgtcagt tgccaaggag acgtgcttgg aagccgagta
    16681 tcccgcacat caaaagaaaa atcgcctttt gcttcataat aacttgtctt caacggtttg
    16741 gggagatcgt taccaaatgt aaaatcatct ggtacattaa ctaatgttaa ttcttgtttg
    16801 gggacaagaa ttgttttagc agatgtttgg acaactgggt taggaagctt agcaccatct
    16861 gctaatgtaa tattgctgga aagtacagct gcctttgtca gtatgctgac ggattgtaca
    16921 gaagtatcta cagtatttaa ttgatagttg taagtaagat gaatggtatc tcctattttg
    16981 ctcaatagat ctgctgggac agaaactcct tgttgaatgc cggtatctgc gatagttgta
    17041 ccatttaatt ttaaggaacc attgatataa gtagtatttt caggaagtga gatcgtgatt
    17101 tttttgtcgg ttatcgcatc cccagatttt gttaacgtga atgtcacatt ttcttgaatc
    17161 gtatctcctg atagagcaga caggggatct cctgtctcag gttgtctgct aaggtttttt
    17221 agctgactat ctgcactcac agatggaaaa ttagccactg ttatttgagg aagagtggtg
    17281 attccagctt gttcagactg ccatttgtac gcaaaagacg gatacatgtt agtaagtaca
    17341 tcgtccacca agcgataatc aaaataatat tgccctgaag ccaatgcagg tagtgtagaa
    17401 gtagctgtat ttacaccccc gttatttgat tggatcgttt ggaaaagttg atctgtccat
    17461 cctgtcgcta atttttaggt tcctttcgaa taaagcctgt aatggatcga accctttttt
    17521 agttcagttg ctgaccaatt ggccgtgact tggtacgatg cagaagaaag gagctttccc
    17581 cactgactat cggctgttaa gtttgttggt aaaaccgttc cgtctagctt gtactgctcc
    17641 aataccttta aagcaacagg agaaagcaat ccgccttgcg catctttccc actgtacacg
    17701 atattggctg tctgattcaa tccacttgtg cttgctggag tatgagtcag tattgctcct
    17761 tgtgtaacgt tttttcctgt aaaatagttg actacgcgat caaagcgact aaatggcaac
    17821 tgatcaaaac gtccttcagt cagccccatc gtcaatgtcc gactattggt agagcctgga
    17881 aggttctggt tatttccatc cacgtattct gtggtatcag caaatgtatt atattttcct
    17941 gttgaatcac ttgttgagat gtaactattc cacgtattta tctctgcact tgcagaaaat
    18001 gcatatgctc ctggattcaa gtttccgcca gttaatttag gataaaatct acctgcagct
    18061 ggagctaaaa tcgaattgaa catacgatct tggataatat tattcgaatc ataaaaatca
    18121 acagaaaaaa cggccttttt agacatagaa ggttgtaatt tacccttggt caaaattttg
    18181 tttggactcg tatcatattt atctccgttt tctgtcatct tcgcgacatt agctgtaaca
    18241 tcaaattgaa gcgggatatc gtccacgttg aattcgcctc gcgtaataat agcaataata
    18301 tctgccaata gagtatttgt atcccacgac cccatcccaa aacgcaaggt atggcttcct
    18361 gctgataata aactaccgct agtaaccttg atgggggcac cggcaatata caagtaggcg
    18421 ttgttccagt caattgcttt taatacatca ctgcttgata catgttccgg caaattgatg
    18481 atcgccacaa atgcaaatcc ttgtgcagtg atattcacca aatcaagtac atttgttagt
    18541 ttcacatggc tttcccaatg aaaacggacc gtgccacctt tccaaggatc atttgaacca
    18601 tcgttcaaat aagtagcagt caatttaggc aattggttag ccccagttag ttggacaagc
    18661 ttcccgccat tgactgcact acgtccacca tttggaggta cgatattttc atacgtgtat
    18721 ggatcataag aaatggcagg aggcgttgct ccaacagctt ctgccgaagg tgaaaagata
    18781 aatatactta aaacaaaaag cgaagtaaaa aagaaggagc gaaaaaatga aaatttattt
    18841 tgtagcaaca tgttcatcct ccttttcctt tcttctccat aacaacaacc acgcaagaag
    18901 ccataattct ataccaatga tcaaataaag aaaacggatc ttttcttcat tcgtctccgg
    18961 gaatacgcca tgttgattag attctttata aatcggtagc tgtgtctgct gttttgatgc
    19021 gccattgact gaaccacttg gatgcggaac tggacttaga tcataaaatg taatcgtacc
    19081 tgaacttttg gtatctgctt ggactggctc ttgccagctg aagaacagca aacttgcaat
    19141 aatccctccc aataagatcg atgttttcaa cgaaatcacc tcatcatgtt gtttctcctt
    19201 ttttcttttt cttgtggacc cacaaaaaca gcaaaatcaa ccataacact agaactgcag
    19261 caaccaatcc tgcataaagc catgggaaag attgttcttg tactgcaaaa acggaatttt
    19321 catttacttt ttgtgctttt tcttttttga tcgtaaagtt ttgtgtaaat cgccattcat
    19381 tactgtcgcc tgattttgct atgatttctg cgcggtaatc gccggctttt gctttatcac
    19441 cagctaaatc aagattcaag tgaaaattcg aatttggtgc aactaaaaat tcattagacg
    19501 tattttcaat ataaagctga ttttcataaa agatcttgct cgtaaatatc aaattgctga
    19561 taatcctagg ctgaggattt tggaaacgaa gctgaacagt tggctttgcg ttgacctcgt
    19621 ccaaatctcc tgataaaagt ttcagatccg gttctatcgt ctcttgactt tcttgtaaaa
    19681 cgactgcgag attataagca atacgatttt tgatttgtgc tccttctgta gcattttctg
    19741 tttcagcttc ttctttaggt gaaacatgaa tacccgctaa tacacgtccc ttaaagcttt
    19801 ttgctgggat tttcacttct ataggtatag ttgtttctgc atgtgctgat acattgattt
    19861 cctttttcgc aatgagcaaa acgtcacgga catcaaacgg caatgtctca tctaacgttg
    19921 ggtttttttg actataatcg atcgttccac catcactcgt taccgccgga ttgacagaga
    19981 cctcaaatgt tcgttcttca tctgaagaat tgctgataat tacttctagt gtctgatttt
    20041 gttccggtgc cactaataaa tcaaaataac cgattgcttt atctatttgg ttctctggaa
    20101 ataccggttt gattccaaag tctcctgctg aatcctttgc ttggctgatt gacggaaaaa
    20161 tgaaaaatag acttaaaata gaaaaaaacg aaacaaacag tcgtttactt tgattcattg
    20221 tccaccacat cctttcaaca acaactgcgg taaaaaatcc ttcacctata gtattttcac
    20281 cgcagtttgt tgaatttatt tcatactcta tgctactggg ccagccacga ggttccaagt
    20341 caaatcagcc gtgaatgttc cagctgctgc tttcggcact ttcagtgtga tatttgctgg
    20401 atcataaaca gaaagccatg ttcccagacc ttgatctttt gctgctgtaa atattggtgt
    20461 cgctgcactt gctttactca acccagttac agtttgacta gttggtccag tggattcgtt
    20521 atctgacgta cttttaacag tggatgttcc aaaatctaat tcagcgcctt gcaaaacttg
    20581 tgaaccgttt acaaaatctg aaaccgaaac tgtcacgttc cacccttgtg cttggccatc
    20641 tgcacctaca cctcgacgat ctgatacttg gagataaggt gtatcgtttt ttgaagcgtc
    20701 tacttgatac gtttttgttc cgctttcaat ctcgtgtgta ccaaatggca attcaggaac
    20761 tacatccaat gttaaagaac ctgtctggcc agttgctgga ttttccggat ctgctggctc
    20821 tactggtttt gaaggatcag tagggttaag aggctcaacg gtatttgttg gttcagtaaa
    20881 ggtaatatct ccttttgaag tcgcttgacc ctcagcaaaa gctggtgttg ccaagccgcc
    20941 tagaagaagt gttgaaagta ataatgtccc aatcatgttc tttttcataa taaatcactc
    21001 ctttttctta gtgacctaag tatagtagag acagtatgca aaaaatcctc atgaattcat
    21061 ccgcttactt gaaattatga ccctttttgt ataaaagaga aaaaaacaat aaaatcgttt
    21121 acatgaatat tcttcctttt ttattaagta tgaaaaaata tttcaatttt attttttcgt
    21181 ttcaaattat tctattagtg acatccttga actataaaaa taggagtacg gcatcatctg
    21241 ccgcactcct atttttttcg tcatttattt cttaaataaa acgattctca cgcaatttta
    21301 tttttttgat atcttctact gtttgtgttc cagctaattg catgaccatt tccaattctg
    21361 ttttaaagaa atcaaacact tgatggactc ctgtacttcc tcctaaagac aatccataaa
    21421 taacgggtct gccaatagca acaagatcgg cacctgatgc gattgctttg aaaacatgtt
    21481 gtccacgtcg tacaccgctg tcaaacacga ttggtacacg tttatctact gcttctgcca
    21541 catattgcaa cgaatcaaac gcagcaggcc ccccatctaa ttgacggcca ccatggttag
    21601 atacccaaat tccaccagca ccagattcta atgatcgata gacatcttct tctgattgaa
    21661 cacctttcac gtagactggc aaatcagaat gagcagcgat aaattctaca tcttttggac
    21721 taagtttttg tttggaagat ttatatacag catccatcgt ttggcctact cctgattgat
    21781 aagcctgaac gatcggcatt ggcagcggga aggtaaaccc gtttctgcgg tctgtttcac
    21841 ggtttccgcc aactgttgca tccgctgtca atacgattgc ttttgctcca ttacgcttgg
    21901 ccacttcaag aatatccaaa ttgattccat tatctttgct catataaaat tgaaaccatt
    21961 gcggtgcttt ctccccgcct gcttctctta tctcttctaa agtacaagaa gcgtaagaac
    22021 ttgctgtata gatcgtccca aaatctgcta caccttttgc agaagctttc tccgccttca
    22081 catgagctaa tccatgagca gcaactggtg ccatgatgat tggtgcagtc agcatttctt
    22141 cgtcaaaatg tgtagttgta tcgggtaatt ctacatctct taatacatga ggaataatca
    22201 aacgatgatt gaatgcccgt tcattttctt gataagtaaa taagtcgcca gcaccactgc
    22261 tgatgtaacc ataaccacca gctggaatca cttgtgaagc cgcgatttct aaatcttcca
    22321 tattgataaa atctactatt ccttcatttg tacctgcttg atatgttttt tccatctcaa
    22381 tgccttctct ctataaaatt tgaatgatga acaatatgat agcgtttaca ctttttatat
    22441 tactcttcga cattgataca ggcaaataat ctgtttacat ttcagccatt ccagatgtca
    22501 ctactctgga agaaatgatt gtaataaaaa tagataaaaa accgatggga ctttgacaaa
    22561 agtagtgtca aagtcccttt ttttgaataa acggtgttca aaagccattt tctcggtatt
    22621 aagtcaaatt tatgcaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
    22681 aactaagcga ctttttcaca acctctcgat aaaacggtgt tcaatcagct gaccctcggt
    22741 attagctcaa aaaatggcaa aatatgagga actattttgc catttgtctc tctaatactc
    22801 aggtcagaac gttgacttca cagtctcttc cttaaacggt gttcaaaaac ttgcatctgc
    22861 ggtaataagc ccaaccaaac gaaaaatagg aggagctatt tttgtttggc tgttcttatt
    22921 acttgatgca gggcaggttt ttcacgacct ctgattcacg gtgtttcttt ttcatcaaca
    22981 tttttacgaa atactgtgga agactattga aataagtgtg gattgtttct ttgtgtttca
    23041 atcgtttctt gccattcttc atttaatttt ggattaccgt tttcttcctt gaactcataa
    23101 ggtcctaatt caaaaatccc agacagtatt tgattcacga tttcatatag ttcagtgtga
    23161 tcagacacat gattcttgaa gatcatctca ttatcaccac gtttgaacct cacattcggg
    23221 ctctcatgat gaacctctat gcatttttct ccttttttta actgacggac ttctgaaaac
    23281 atctcataaa tatcttctcc agtaaaacct tcagcaagcg ccagactgtc cacaagaccg
    23341 cctactgtca gttcagagat tattgcttga ttggaatcta attttaatgt atagcttgtc
    23401 gcttctacta cgccacatgc attgcaaccg ccttctgata gttcgctttt tctaatcaat
    23461 tgaacttctt tcattttctc ttcctcctct taattttcta cttatgtatt tttatcacct
    23521 gacataggtg actcctatca acgctatcat gtgctttttt cctcagaaat cctatttatc
    23581 cattccatct atcccttatt cttctacttt tctttctcta gcatataaga gatacgcata
    23641 gtattcaagc aaggattgtc gatataaaaa gaacaaatac tgctattttg atttcttttg
    23701 gctatattac atataaataa aatttatcat acctgctctt tttgactata tcatcatctg
    23761 acttctatac ttcgtttgta ttaaaactta ggaggaatca ttcatgctta cagggttaaa
    23821 cttattaaat aatccttttc taaataaagg aacagctttt acaaaagaag aacgggcaaa
    23881 atatggaatc actggtatgc ttccaagtac tgtccaaaca ctggaacaac aatctgttca
    23941 agcttatggt caatacttaa gcaaacaaac agatttggaa aaacgtatct tcttaatgaa
    24001 tctattcaat acgaatcgga cattgtttta taaattgatg ggcgaacatt tagttgaatt
    24061 catgcctgtc gtttatgatc ctgtcgttgc ggattcaatc gaacaataca acgaaatttt
    24121 cttgaaaccg caagatgctg catttctttc aatcgacgaa ccagaaaaca tcaaagcaag
    24181 tttgaagaac gcggcagatg gacgagacat tcgtttgatt gttgtgactg atgcagaagg
    24241 aatcttaggt atgggcgact ggggtgtgaa cggtgttgac atcgctatcg gcaaattgat
    24301 ggtctatact gctgctgctg gtattaatcc agcacaagtt ttgcctgtat cgatcgacgc
    24361 tggtactaat aatgaagaat tattgaataa tcccttatac ttaggcaatc gtcatgctcg
    24421 tgtagaaggc gaaacttact atgaattcat cgatcaattc gttcaatcag ctaccgaatt
    24481 attcccagaa ttgttattgc attgggaaga ttttggacga ggaaatgctg cagcgatctt
    24541 agaaaaatac gaagatcaaa tcactacttt caacgacgat atccaaggta caggaattgt
    24601 tgtcctagca ggtgtattag gcggattgaa tatatccggt gaacaattga aagatcaaat
    24661 aattttgaca tttggtgctg gtactgctgg tgtgggtatc gcaaacatcc ttttagatga
    24721 gatgatccgt caaggtgtac ctgaagaaga agcacgccaa catttctatc aagtagataa
    24781 acaaggttta ttgtttgaag atacagaagg attgactcct ggtcaaatcc cattcgctcg
    24841 caaacgctca gatttcacta atgctgatga attgacaaac ttagaagcag ttgtaaaagc
    24901 gatccatccg acaatcatga ttggtacttc tacccaacct ggagcattca ctgaagaaat
    24961 cgtgaaagaa atggctgctc atacaccacg tccgatcatc atgcctttgt ctaatccaac
    25021 aaaattggca gaagcaaaag caaaagattt aatagaatgg acggacggaa aagcattagt
    25081 tggaacaggt atccctgctg ctgatgttga atataatggt gtaacttacc aaatcggtca
    25141 agcaaataat gctttgatgt acccaggttt aggacttggt ttgattgctt caacagctac
    25201 acgagtaaat gctgaaatca tttctcaagc tagtcgagca ttaggcggaa tcgttgatgt
    25261 aacaaaacca ggagcagcta tcttgcctcc agtagcaaaa atcactgaat tttctcaaac
    25321 gattgctgaa actgtcgcaa aatcagttgt cgcacaaaac ttgaatcgtg aagaaatcac
    25381 ggatatcaaa gaagcagttg aatctgctaa atgggttcct gaatataaat ctttagaaga
    25441 ttaagatcgt tatagtaaaa gaacatacag aaactttgta tgacgtctaa aaagaaaaaa
    25501 gcgactgcgg caaaacagcg gccagccaac tcctgctctt ttgtcgcttt tctttggctt
    25561 ttttcatatg atacagaata agaaaggatc tgtaaaaatg gcacaaaaaa caacaactgc
    25621 aactgcagtt gaggaaaaga aaaaagaagg tttttggtcc acaaaaatca ccggcgtaag
    25681 tttgccactt tatttgatca tggtccttgt cctgatcatt gcaatggctt tagggaaatt
    25741 accgacgaat atgattggac caatcgcagt tttggttatt ttcggtaatt tatttcattt
    25801 tatcgggaca aaaatcccta tcgtcaaaag ttatttgggt ggtggttccg tttttgcgat
    25861 cttcgcttct gctgcgattg ctacatttgg gatcttacct gaatatgtag tgaaatccac
    25921 agaaaacttt gtcagcaata tgggcttttt ggacttttat attgctgcct tgattactgg
    25981 tagcatcctt ggtatgaacc gtaatctatt gatgaaagct tctgttcgtt ttattcccgt
    26041 tgcacttatt tcaatggtcg tctccttttt tgccgtagga ctcgtgggca tgcttatcgg
    26101 aaatggtttt gcaaattccg ttttatacat ctcattacct gcgatggctg gtggtgttgg
    26161 agccggagcc gttcctttat caacgattta tgcaaatgtt ttaggtacgg atgcttcttc
    26221 tatcatttcc cgcctgattc ctgcgacagc aatgacaaat gtcttagcta tcatcggtgc
    26281 agcattagtt gctcgtgctg gacaatcaat gccaaaattc aacggcaatg gtaaattaat
    26341 ggaaaaaggc gatcttggcg atggaaaacc tcgaactgtg aaaccttcca ttccacagtt
    26401 aggtgttggt ttgatggtat cattgacttt cttcatctta ggacaaattg gtaactattt
    26461 tgttcctaaa gtccatgctt acgcatttat gattattatc gttgtcatct gtaaaatcgc
    26521 caacctatta ccagagtatt atgaagatgc agctatcatg ttcaataact tgattgtcaa
    26581 aaacttgaca gcagctgttc ttgccggtat cggtattgcg ttgctgaatc tgaatgtatt
    26641 agcttctgct ttgacatggc aatttgttgt cttatgtctg acaagtgtta tcgcgatttc
    26701 agttgtttca ggatttgtcg gtcgtttgtt tggtttatat ccaattgaat caactattac
    26761 tgctggctta tgcaacaact cgatgggcgg aacaggaaat gtagccgtct tatctgcagc
    26821 taatcggatg gaacttattg cttttgctca aatgggcaat cgacttggtg gtgccatcgt
    26881 tttgatcatc tctggtttct tgatgcaatt actttcttag tcaaaaaaac aaaaatacct
    26941 gatcatcaag tatcggcttg gtgatcgggt atttttttga taaagattta caggattttc
    27001 aaaaatcttt tttgcatttt atcggaatga taaccgatgt gttcataaaa ttggtgtgct
    27061 tctactctgt attctgcaga attaagcctt attgtcgtta ttcctcgttt tttcgcttct
    27121 tcttctacgc cagtcatcaa agcctttccg atgcctcttt tttcagcata tttagacaca
    27181 gcaagtgcca taatattgaa cattggatcg ctaaaaatcg attcatagga ctccgcttgt
    27241 acatagccag ctgctttttt agaagtagga tcttcataaa ccaagaaaaa atttttctct
    27301 ggctccttca gcagtttctt catttgtctc accgtaacgg ttaatggtat atcataccct
    27361 aattgatccg cattgatttc acgtagtgct tctgcatctt ctaaacgcat ttcccgtaac
    27421 atccaaatca ccagccaatt tctgattttt taaaatgaat ttttttatca tagtatactc
    27481 tttttttcat ttagaacaat atgtttcagt gattttgact tgcgttagtc tagattctcc
    27541 taatgtttgt aagatgacaa aggcattgta acaattgacc aaaagaacca cgaggacaat
    27601 tacttgaaaa ataaaggtca ctttttttgg agacaaaacc ctgctaaatc ttgctcccca
    27661 caaacctcca ataacagcag cggggataac ataaaacaac atagataaat caaagcgcat
    27721 aaagctactt gttaaagcaa tcgttaccaa ttttgccagt tgagaaaaga aaatcgtaga
    27781 tagagaatat agtgttgctt cttttattgg caatgcaaac atcagcatca acaaagaaac
    27841 attgactggt ccaccaccaa tacctaaaaa actagctaaa aagcccagaa cccccccaca
    27901 tataaggtac caagtccatg acgtcaaatg aaattttggc tgatgatgct tggtgtagaa
    27961 gaacgcaaaa accaaggtca ataccgtcaa aaaaatttgg atcagctgca catgcttctc
    28021 gttttcaaat aactgtaaaa aaacttcgaa tacaatgttg ccgactactc ctccaacaac
    28081 agctccacta gatacccaac cgacaatctg ccaattcagt gatttcccgc ttgatacttg
    28141 tcgcacagtc gaaacaatgg acatcgtgaa taccgcaact gttgagtaaa aagaaatccc
    28201 tgcaacagaa tgggcgccga taagatcaag aatcggtttg atcaacacgc ctccacccat
    28261 cccggaaata gcgccaactg tgttcgccag aacgatcacc acaaaataaa tcagaccaat
    28321 catcttgtat ttcctttctc ttgtttatat cttttagcga ttgttactct tttcttttat
    28381 tatacagtaa aagaaacaaa cgaggcttcg aaagcttttc tactttttaa ggaaatttag
    28441 tgctaaacga aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa
    28501 caaaaatagc tcctcataat tttcgtttgg ttgaacttat taccgcagat gcaagctttt
    28561 gaacaccgtt taagaaagag gtcgtgagcc tgccgttcag ctccgagtca caaggaacaa
    28621 tttcaaaaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca
    28681 ggagaacacc gtttaaggaa gagactgtga agtcaacgtt ttgacctgat tattagagaa
    28741 acaaatggca aaatagttct tcatatttcg ccgtttttcg agcgaatgcc gaggggcagc
    28801 tgattgaaca tcgtttattt ggaaaaaggg attgtgacaa gacgtttgtc acaatccctt
    28861 tttttatatc ttattaattc attcttttgt tctattcttc ttcttccgcc atgaatgaga
    28921 aacccatatc aaagaactat aaaggttatc aaaacagcgt ttatgactaa atgaattaga
    28981 gttatctatc actatttttc aagcgattta aaccaaatgg catacaatat ggcatacaaa
    29041 aacttcaata agccgtgggg gtttttaaat ttcttcttgt tctttaaaat caatgagtgg
    29101 agctacataa tttgaatcca ctttttcaaa cgtcactttt tgcatcgacg aatgttttct
    29161 ttcccaagat aacgtaaata gatttgactc tggacttata aagtctactt caccttctag
    29221 tattactttc ttatgcaaat attcctctaa taaatataga cttgctaaag catacaacac
    29281 attttccaaa tttgcttcct tataatttga agaacgacca tgttttactc tgttatatat
    29341 tttccaccaa tctggtgtat cttcaggcca cccatctcca aaaggtttta gtgaagtcaa
    29401 tgttaaagaa ttcataaccc taacaccatt atccaaacac attaattcgc tagatttaat
    29461 aacagcttta aaatcagtta tgcttttatt gctactgcta tcaaatccgc aaagttcttt
    29521 gaaaataatc tcacactccg aaccaatcgc tagtagtagt ttttgatatt caatagagaa
    29581 tgttttgaaa ttattctcat cgagcatcac aaaatctgtg gtattaataa actcattttc
    29641 taaatgtaga taatacttcc aataaaaatt tgtaaactct gctttgtcca ttaaatcacc
    29701 tcttttgaat tataacaaaa aaaacacgtc cacaacagac gtgttctttg atttctacac
    29761 aatcagcttg ccaaaaccat ccaatcagtc ctagcatgcc tgtattaaaa ttgaacgttc
    29821 atcatctatc atctttctta gtccagcatg tttgcaacca cacctacaat tttcagtcca
    29881 acaatagatt tcgactagct aagtcttgca aaattcaggc agctaaccct tcatttacta
    29941 ccttaattat actaaatacc cacaacgttt acaagtgtaa tcattctaag aaatctgttt
    30001 agctatgatc gttgtataat ctttaaacgc cgttccttca ttgattgaaa taattttata
    30061 actcttgttt ttccaagcta ctttcatatc gtttgttagt tcataatctt gatcgtatcg
    30121 aataataaac gtcaacgttc cttcaagaat ggtacctaca ctagcaagca cgtcttttag
    30181 catttgtgaa cgcacattag cccaacattc aaatacagtt tcttcactat ccaccatctg
    30241 cccatcttca tcttttaccc gttttgtctt tttaaacttg actctctcag tcaattcatt
    30301 tacattctta atgattggca taataagcac ctctcatttg ttgtactaat gcttgtaccg
    30361 ttactggtat ccgttcgctg ctggcttctt gacggttcaa ataccaatgt tgagtaagta
    30421 atgacaccgc caaatcaaat tgctgataat tatccatatc tttatccgtt gcgctactat
    30481 caatagcact ttttatatat tcgcctgctg tatcaatcaa ttgttgaata aagtcatcat
    30541 caatagtgtg atcgatccgc atactttttt ttatgctatc caaaattacc attttatctc
    30601 tcctaatgaa aaaaaggcag tgggataaac cgccgcccaa tatttttcta tacttttggt
    30661 gttacaactg gcgtaaactc aatatacact gaagcatttt gatcaatttt cttataatcg
    30721 ttgcgaacga tcactgcaag tccttgtgag tagtaatcga atttttccca ttgagtcgtt
    30781 acttgatttc tacgagcaac aaagatagat tgtgcaatat cccccataat catagggaat
    30841 gttccagctt taggattggc aaacaatgta tctgcaatca atactactgg cataccgaat
    30901 aatgatttac cactaggtgc tgtcacatcg ggttgtaaaa tgtaacgtcc atctgaatct
    30961 ttcaatgtat ctaggtggta atatccgctt tggtttagaa ttaccatttt atttaatgct
    31021 gggtctaatg ccacattgta tagttgtttc aaatcgtcca acgtagcagc cgttttctta
    31081 gtgaatgttt ttaataaatc catgatatgc ttattgtcag tgttttctac caatttcgct
    31141 aactgatctt tgacctcttg tacaatattc actgctgaat cttccacaac ctcatttgat
    31201 aaggcaatct taccagcacg agtttctact ttataatcaa ctgaagtaaa catttcagcg
    31261 tcaatatcac caatttcagc aagttcagct tttgttgcta acactgcttg ttggttagtt
    31321 gctactggat atttaccttg tccatttgat actgttttta ctgttgcata ttgagctaag
    31381 ttataatttg aacgtttcaa atcaaagact tcaccgatta cttcttcggg aacaactgcc
    31441 gctgcattta cagtagtgac tccatcacgc acttcgcctt gtgaacggat atattcttca
    31501 tacccacgca attctgtttt ttcgttatcg attaaagttt tttccatgtt attactctcc
    31561 ttttgtgctt tagaagtgga ttctaagcta ttgtttgttt gttttgcttg gttgttactc
    31621 ataaacgatt cgtaagaacg cttatttact tggacatttg atgaatcata agcgggaacg
    31681 gtcacgacac taatttcatt aagtgctttg attttatcta ttgatcgttc aattgtgcca
    31741 tcttcttttt tgtcgaatga atctaatcca agcacgaacc caaaggacat agaatcaaca
    31801 accccttttg agatattctc atacacatca tttgaatagg tcgtgtcggt tagctctgct
    31861 tcaaaatgta atcctgtatc atcgacattc aatttcaacg tacctgcttt gacactagct
    31921 agtggctttg aataatcgtg tccatataat aagaacacat ttgataaatc cacctctttt
    31981 aatgcttcgg gtgtaatcac ttctacaaag ccgcctaaat cttttgacgg ttgcccgaat
    32041 ttcaacgcat agcctgaaat agttttgccg tctgttggtt gtttttcatt ttctttctct
    32101 actttgggag aatcggctgt tagctcagct tcttctgtca gccgtttttc cttttcttct
    32161 tcattattca actggtgtaa ctccttcctg ttcttttaat tgatatttct ccaacgtatc
    32221 taaatacgta aagttcaaac ttgctagtaa acgatcgcca ccatccatgg ggggtagccc
    32281 cattttcgac cgcccctcat taatcgtgag aagtgaccct ttgacctgat ccaatacatt
    32341 ttttactttt gtttcaggat cagtctctag taactgatcg gaattaaagc ggatattggt
    32401 ttcaagtttc gtatctaatt cactcacaaa cacattaaag taatgaatca gcgtactttg
    32461 gatatactgg agattacttt gaacggtgct agaatgttca ttttcaacgc ctaaacgctc
    32521 aatcggtaca ccaaacgcct tggcaatttg ttttgtgttc caatcattgg aattgataag
    32581 cttcaaaaca tcggtgttta tttctaatgt tttgtagtcc attgtttcat caagaatgat
    32641 cgttctaaga gcattatctc cactacttga accgttggct tcttcaaact tttcacgaat
    32701 tgcgttcttt gctgatccgt ctaaatctga cttatgaacc ttcaaaatac ctgacccact
    32761 gacaccacga gtaaagaaat tgtgcaatgt gcggttgcca gcttgttgaa ttttcagttc
    32821 atcacgtaac gcataaagtg gtggtaatcc tgttaaacca tcttgggtga aatatttgaa
    32881 gtgcaaaata tcgctagact tcacacgtct ttttttatca ccaatctgat aagacaacgt
    32941 accattatct aattgagtaa ccgttacact tgagttaggt aataagtgaa tttcttctac
    33001 cttttcaccg ttgcgtttaa tctctgcaaa gctattaccg tttagcaaca tattgaccgc
    33061 caaagcaaac tttaaatgcc aaccatccat ttctgaatta ggtttctcgt ttagtaactt
    33121 caccagttca ttatcagctt gtggcatatt gtttttgacc aattgaatcg gacttgaagc
    33181 aatatcacta gcaataattc gaacggctgc aaacacatca ctatttctta atgcacgaac
    33241 gcttgtaaag ctggtggtgt aatcatccga ttggattgat accacatgtt gtaggaaagg
    33301 atctcccgtt gtattttgtc tcgctttaaa aaatgccatc ttttaacctc ccttctgttc
    33361 tgtatttagc atgaccgcta ccccaataag cactatgccc agcgctaaca agccatagta
    33421 gacatttgtt agtaaggtga tagcaaccaa cacacacacc aatccaagaa gtaaaagaac
    33481 ggtatgaatg taattagaaa gaaaattctt cacttgtata aaattcattg tctgctttcg
    33541 ctccttccgt tgtggtgaag taatccattg caaacacata ggcattgatt aatgcagcta
    33601 ttggatcaat tttgttactg ttctttgatt tattaatctg aatgccgttg ttatccgttt
    33661 ttaaaatagc gttgttcact gcatgggtga gaatcgtatt tttattgtga ataacgttgc
    33721 cttcataaac ttgttctcta aaagttcggg tcggaacgtt tagagtaatc gttccttgtc
    33781 ttacttctaa cattgggtag ttggcttttt cagctttact gataagcgaa ttagcgttat
    33841 acgggtcata acaaatcccc atacattcca aatcattttc ttgaatcaaa tcttgaataa
    33901 actgaaatac ttggtcatag tccacgattc cactttctaa ttgagtaatg gaacactcac
    33961 cagctttttc tagttctcga taaggcaaac cgtcgcgctt ttctttgtct tgaagcccat
    34021 atttggtggc tacaaagcta tgtgaatcac aataaagttc gccgttatct agcggtacga
    34081 tccatgaaac gctagttaaa tcatctgttt tagataaatc cactccgata taaacgggct
    34141 tgcctgtaat atcttgtggt tctacttcgg ttgcctgcca gtcttcagca atcatatagc
    34201 tgtcctcact cgcttgtctc cataaattga agtttttcac caatacagaa ttaaggttat
    34261 tttgtttcaa agcaaggttc acatcatctt gaatggttgg aatcattact tttttgattt
    34321 cttcactttc aaaaatcgga ttggctttga tccatttctc ttgatcgtga atttcttcgg
    34381 gatcgtccaa ttcccatatc gctataaagt acctgtcggc ttgttcttcg ccttttagca
    34441 cacgatctaa caataagtat tcctcgtaca taggaacgtt taaatcaagc ccagcggtac
    34501 taataacaca caataagccg ttcttttgtt gggtcattcc tgacttaatg acgttgtacg
    34561 ttttacgagt ttttgcttcg tgccactcgt caagaattgc ggttgttggt gcaaacccat
    34621 ctagcgtgct ggtttcacta gccagtgcca tagcgaacga attagagggc aagtgctgaa
    34681 tcttagagtt cataattttc agttgtggtc ttaaaaactt actagacttg accacgtttc
    34741 taagtgaatt agacagcata tcatagccca atttagcttg tttcaaagcg ttacttacaa
    34801 acaatacttg ccttgcttct gctggttctt gttccataat caacgcattg gcagccatgc
    34861 cacttgcgat atacgttttc ccattcttac ggctcatact ggtaaacgct cgattgaatc
    34921 gcctgtaatt cccttcttta gtacgccagc cataaagact gcctagaatg aatttttgaa
    34981 atcctaacat cttgattgct ttaccgtccg tagatggtag caactcaatg aatttaatcg
    35041 ctttggtggc ttgttcttca tcgaacacat aagggaagct atctgactta gaacgctcca
    35101 aatcgcttat atgacgctca cacgcttgga taattttctt gggtgcaatc agcttacctg
    35161 ataggacttt ctcaatgtaa tcattcatga attcatcaac tctttgaacg ggtcttcggg
    35221 ttcatcattt ttaaccttgt tcaaagctag ttttgatcgt gattctaagg tcatacctag
    35281 tgaggtggct tgttttttca aatcactcat agcttgtgat tgaacccgaa ccgctggatt
    35341 ggctttcttt actccgtttt cgcatgtgat aaacgtacct gattttctta tctcggcttc
    35401 ggctgttttc attcgagcaa aggctaaaca ataggctacc aatgaaccat aatctgcttc
    35461 actcaatgga taatcttttt ttaatgttgg tacgatacga ttccattcac ttctagcgct
    35521 cgctgccatc cagtcagggg gcgtgatatt tattaatggt tgctgcttga acaattcttc
    35581 tctagcgtcc acacggattg ctttttcttc acttgatata ttgccttttg tatcgtgtaa
    35641 tattttaggg tgtcccatgt tgtcctcctt tcagacaaaa gaaaaaggaa cgtaagcaat
    35701 taagctcaca ttccttcgtt tttcgatcag aatttttctt tatctaattt atctatataa
    35761 atgatttttc cgttctgcat ttgaatggtc acttgaccaa aatgaggtaa ctcaatggtg
    35821 cgctgtttcc ctgttttatc agtaataaca attgtatttt tcaataaatc tcctactttc
    35881 attatatact ttttcacttg tgattacaag tgtaatcgtt atttgtaatt acccttatgc
    35941 cttttcacaa cggttatttg taccaaaatg agtaggcatc gattgtcagt aagtttcaca
    36001 ctatgccccc ttaactcaaa gggtactctt ttctcgtctt tgtctttcat tggctgtctt
    36061 ggaattatgg tgtgcatggc ataaagaacg aaaattagtt tcatctaacc gtctattcca
    36121 atcatctttt agttcaattt tgtgatctac aacatcagct ttccttatca agccttcttc
    36181 taggcaatcc tcacatactg gatgatttaa ccgatacaag tatgaagcct ttcgccatgt
    36241 tctactttga tagaattgaa aatatttacc ttcgctttgc tttctttctt cacgcttaat
    36301 tgccgtttgc tttgctttat gcttcccaca atacttctgc ctataatcaa tcaatgtttt
    36361 acatccagca tgattacatt gttttttaac tgccatagat taccaaccaa agcgatctcg
    36421 ttcgtcagaa tcatcttgtt cccattttga tttgtattca atataaggcg aaactatctt
    36481 caagcacgtt ccgtctttaa aattaacttt agtgatttta tcttcctcaa aactaataaa
    36541 gtctacatct tcttgagtgt ttgaatactc aatgtgtttc tcaccatcga agtatctaat
    36601 actttccata tgcataatta ttctacctcc aataaattag ttatcaattc atcatctgtt
    36661 agtagcaaag ccaagaactt atcatggatg tttaaaaaca aattatcctc attcgatgta
    36721 agctctcgtt gtctcgctcg atcatatagg ttaagcagac aattaaattc atccattagc
    36781 tcacctgtat catcatagtt gccactatct accaatgatc ccactactag cgattgacac
    36841 cacgctactg actcctgcag ccaatcaggt tcttcttcca ttatctttaa tacttctgga
    36901 tcaaatgtgg aataatcttc tgttaccaat cccacactaa atgccagcgt gttcattaga
    36961 aaccgatcca tttcatctgt atattgaaag ttcggtgctt tgtttgttga aataatattg
    37021 agcatttact ttcctccttg attcgtaaca cgtggtaaca cctacgtaac aggtacccgt
    37081 taccactcaa tcccaacggg gacaagggtt ctagcgtttt ggtaacaggt aacgggtaaa
    37141 atccagtaac attattcccc agcatattag ctaactattt caaaagtttt aaggaaataa
    37201 ggtgttaccc cgttaccaaa ttgctgtatc ccttggggca gtaagggtaa actagtaacg
    37261 ggctaggtgt tactgacccg ttactacccg ttactttttg tactttccag ctcgattttt
    37321 attttcatag gcatttgact tattgtaaaa tcctcgtcgt ttatttcttt ttggcagttg
    37381 cttccgttcc caaccaggaa tactgctaat aatcaaggca atctttttag tttctgcatc
    37441 tgatcgacca ttcaataaat cctttgcttg tttatcaaaa acagcttcca aaatatcagc
    37501 ggtgagtacg ctatcaacta aataaaactc ttgttgcata gtagctccat tatagaaatg
    37561 ctgtaaattt ttctcattac atttactgtc aggatagttc tgataataag aacgtctcgc
    37621 ccacgctgga gcttcttccc atttatacgg gatttccatt tccaaatatt tagtgattgc
    37681 ttctttaatt ggattctcca tcttggcatc ctcttgatag tcttttgcaa tttctaagac
    37741 ttctttatct tcatcgggac taaaatagat tcgttgtcct ttatcaaaaa gcacctttgc
    37801 ttcagctaac acttgaagaa aatattcatc ctttgtttta aacggattca tctttggctt
    37861 attcttacaa ggcaaaggat aaaaacggcg gtttcctgta tcatctttca aatactgccc
    37921 atcattcgac gttccaataa atacacattg ccttgcccaa gctatgacat tccgaccata
    37981 aggaggtcta attttatcga tcttggcact gatgaagttt tttatctgtt caattttagt
    38041 tttgttcatt gaagataatt ctccaagttc aataattaca ttgccttgaa gctgcatata
    38101 atcatctttc ttttcaccta gcgaatctaa tgaatcggtg aaaaaatcat ccgtgtaaag
    38161 taatgctgga acggtactct caccaatccc ttgcggtcca tccaaaactg gaacgatctc
    38221 aaactttatt cctggtttat agatacgtgc gactgatccg actatccaac gttttgttac
    38281 ttctcgtgtg taaaggttgt cgtctacccc taaaaggtca ataaacagtg tttccagtct
    38341 aggctgttga tcccatttaa ctttttcgat acgttctttt actgggttga aaacattctt
    38401 tctagccaca tttactactg ctttgtgtat tttgttgtca tcaaaaacta cattgtagtt
    38461 ttcttcaata tatgccgtta aggcatcctc aaaactgtct tcccattctc cagcggtacg
    38521 attgatccaa ggagaatctt ttaataggtg aatgtatccg ctaaattcgt tataagcaat
    38581 tgttccagct aaattgctat cattggttaa aatcaattct gcattcacaa cactgttact
    38641 tttaatctga tcgtctttat tgcatcttaa tcgtgacatc caggttttca attcaatgat
    38701 attgtcttca cgctcgctgg cttcgggaaa gtctaaaata ctatctaatt tatgcttatg
    38761 agccatgagc tttccccctc aaatcttttt taatcatcga tcgaataatt tgattcactt
    38821 ctttatcttt tagcggtggt tcattgtacg catttgctgt ataaatcaat tctgctaaag
    38881 tttgattatc tacaccgtgc catagtaacc aaccgcataa cttagttaaa tgatcgtttc
    38941 tactaccttc gccagcgcct tgaacaatca tatctaattt ttttgctgtc cctgtttttg
    39001 ctacgggtcg gtattgagtc tttatttctt gcggtttttt tagcagtagg ttcactagcc
    39061 aatcgggagc tggtgcaata ttatttagag atacgttttc aataggttca tatgctctcc
    39121 caacacttct tgaaataatc atagttggcg ctattggaac tcctttagtg ataatatcaa
    39181 tcccgcttaa acttttacct ttatcatcac gcccgaagat atcagcaaat gcacctgttt
    39241 cttgttggat aattacacca tcaggaattt taaagaagaa atggattcct ttacctggtg
    39301 tgatttccgt ataagtagaa ggaaatggat catacattga agcaagtttt ttataattct
    39361 caacgccgtt tcgtgtttca gaatgttgat ctaggtcaac taccaccatt tgatgatctt
    39421 caagcattaa cccaatattt ctagttgcat cttccgtcca ccattcatta atttgattag
    39481 aatcgttagt tgcatcattc caaccactag agccttttat tggaatttta gttccaggag
    39541 ataagggata aattgaccat cccgactttt gtaattccgt tgctgcttga taattatttg
    39601 ccaataaacc tctcctcctt tttcaaaata ctggtataaa tcattcagac acctccatga
    39661 gcttcaactg ctcaagttcg tatttcaacc catcccgaac aaattcagca ccttttaatt
    39721 gattctgata ctttacccat gtattaaatg ttttcaccct tgcttcttgc atatcagtaa
    39781 tgtttaacca tgcggttaaa atctgatttt ttagctcgtt gatttctcga caaattattt
    39841 tgtgttctgc atgttttttg agtacataca aaactgttag tttttcattg aatgaatttc
    39901 caaagtaggt tttcccgata ttattttcta gttcagcgat cccttgatta atttcctcta
    39961 attcaaggct atcgagttgg tttaatagtt ttgttttgta catctactta tgccctccag
    40021 ttcttaattg atagtcgtac tcgtcataag cagtgaagag atataacgct aatcctgcaa
    40081 agatagctat ttttgcaatt aatggtaata agccgaaaat tccgccgatt aaaatgcttc
    40141 ctataattaa gtttcgtttc ataatggttc cctccgattt tttaatatgg tataatcgga
    40201 acaaagaata tcgggtttta tcccaattaa gttgccttta tcctgtccgc caagactgtt
    40261 atggataagg ctttttcttt gttctcgatc atgttaatgc tcctaagttg tctgcaattc
    40321 agcagaacga ttataaattt tctcactcac tgaaaactgc aacccatatt tttctttaac
    40381 agtcattaat tctactgtct catctaaaat aggttcacga tcaaccaaca tttcaggagt
    40441 catatctttc ttttttacca ttttggaatg accataaata gttgatacag ctttattggc
    40501 tatcacattc gctttaatgt agtctactgg ttttggttca gtaatagcgt ggcttaattt
    40561 agtcattgct tctttttggt gttctttgtc tagcatgcgg aatacttgaa agccttcaag
    40621 tcctgtggac tggcgtagtt ctttgatgat gtcgaaaatc cagtcttgaa atgcctcggc
    40681 ttctttttta cggcttttga atgccatgcg gtaaatattt tttttcgttg atgatgttta
    40741 catcttgtgt tctgcccaat gaatcgatga ccttactagt agtaacccca tctttaggca
    40801 aagagtgaat ggctctagta acctgtttaa gacctaacgc ttccgcaaca tctttcgcca
    40861 ctgcccacca ttcatcatta atatcgacaa atcttataat gtgtccgttc caaatttcag
    40921 ttttcattca acgtcctcca gttcaagccc tagcaagctc gctaacaact caacttgctg
    40981 atacaaaatt tcttgatact cttcaataga aagtcgttct ttaaactctg cttgtactaa
    41041 atcgttcaag ccacgcaata ctccgcttac cgttggttct tgtggtagca atttttgata
    41101 gtccatttgt tcgtacaaac attcaaacgt ttcttctagc gctttgcctt ccaagtttgc
    41161 taattctgcc gctgtgtctt ctgtaagaat tgttgataat actttttcga ttgctttatt
    41221 ttgtgtcgat tccattatta tttcctccta ttaatccctt tgcccccacg gcttgcgttt
    41281 atttttggta ttcttccata aagcgatcac attcatcttg tgaaattctt acgactccat
    41341 caactataat caactttaaa ccgttaggaa catatttctg catcatagta ttgtatgaaa
    41401 cgttcatata cttagcagct tgtgccttgt tcatatattt tggaaactgg tacttttttt
    41461 ctaataatga aagtaacgtt ccttgagttt gctctacttg ttgaacaact cgatcgtcaa
    41521 taattttaaa agctggatca tcaagcgtga gtttgtcaat ttttaattcc atatttatcc
    41581 cccctcgtta gcatacattt ctatacaaag attttaaaaa aatgcaagag gctcttgaat
    41641 acatttctat acctcttata aactcaatat accatcatac cttttcattt gcaagaattt
    41701 taacatactt ttttgaactt ttatgtttca cacatattta aatcgtgata tagtagagaa
    41761 aatatatgaa tggtggtgaa aatgtggcta gaaaaaaata ccccgaagca gtggagacag
    41821 gacaaagaat tagactggct agaattgaaa agggactctc aatggaacaa cttggaggta
    41881 aattatcccc accggccagt aaaggtgccg ttagtaattg ggaaaatggc tataatcttc
    41941 ccaataacac caggcttaaa caactttcaa aggtattaga tgtatccact acctatctat
    42001 taaacggatc ttatacatta agagatatgc atatgatgcc cgaaattaag cgaaatgtgc
    42061 ttgaaaagca attgaaaaaa actattgaaa aaaataactc tataattgat tctaatcttt
    42121 ctaatgctat caataacatc gaagaagata acctgactgt ctcacagaag atttatttaa
    42181 caaacgcaat aaaatatctt aaaacaggat ctcgaattga atttcctgac gggagtaccc
    42241 caattgctta tctcgcagct cttctaaata cgcttttacg atatgactca ttaattaatg
    42301 attcagaaaa aaatacagat gagaaaaaag agtatcaaga attttatgaa aatgatcttc
    42361 taaaagagtt cacagctctt gttactgagc taaataaaca ctattcaaaa taataataaa
    42421 ctgcctcctc caaccgcccc cacggcttgc tacactatgg agggaaaact attatggcaa
    42481 cattcaagca atatgaaact aaaaaaggta aattttggct ctatgaagcc tatcttggaa
    42541 tgaacaaaat gactggcaaa cctgataagg ttcgtagacg aggttacaaa acaaaaaaag
    42601 aagcccagct tgccttgtca cgcttgcaag tggactacga taaaaacggt attaaaaaag
    42661 cgaacaacga aacgtttaaa gaagtttatg acttgtggct agaaacatat aaaaccactg
    42721 tccgagaagc caccttcatg aaaactgaaa tcaagtttag aaagtggatt cttccaaaat
    42781 atggaaatct tcgtgtgaat gaagtcacgg taaaaaaagc ccaacaaatt gtaaatagct
    42841 gggctgaaac tactgaccaa tacaaggtac ttcattcaac ttctaagcgt atttttagct
    42901 acgctatcaa tcttgggatt attgagacta atccactaga caacgtatta atgcctaaaa
    42961 gaaccaccac taagcataaa gaaaaggtca aagtttacag taaagaacaa ctgatcacct
    43021 tgtttgatta cctaaacagc aaacctgaaa cttatcgaaa cgactttgat aaaacgttac
    43081 tacgctttct cttttatagc ggggttagga tcagtgaagc ccttgcattg aattggtcag
    43141 acattgattt tcaagaaaat acggtcacca tcaataaaac actaagccaa tccaaaaatg
    43201 gctataaaat cagtgatcct aaaactgatt gtagtgctgg ggttcttcca ctagatgaaa
    43261 gaacaatttc tatattaaaa aaatggcaga ttaatcagcg gaaatatatg ctgacacttg
    43321 gtgtaactga tccgactatg attttttgtg gtatctataa agaactaatc acacaccacg
    43381 ctatttatgc aagattgatt actatttgtg aaaaagctat ggttccattt ctcggtgtgc
    43441 atgtagcaag acacactcat gcttcaatgc tcttggacgc tggagctact atggtagaag
    43501 ttcaaactag attacggcat acaaaaatta gtcagacgat cgattgttac ggtcacttgg
    43561 caaaagaaac gaaagaaaag actgttgaaa aattagtaca acacttaaat attgactaga
    43621 tggcatacaa tatggcatac agtaaaaaat aaaaaaagga gaaaccctat catatcaagg
    43681 tttctcctag ctttatagtc tattcttctt cttccgccat gaatgtattg aatacttctt
    43741 caatcatgtc ccattctgcg tctgtttcga tttgttctaa ctcgccttct gttccatctt
    43801 cgttttcgat gtatgcataa gcttgtaatt ctacatcttc atcttctgaa acaccagcag
    43861 gatataaaag aacatagtta cgtccaaatt cttcttgtcc gtcaactgtt agtaggattt
    43921 catataatgt ttcatttcct tggtcatcca ccaatgtgat gtgttcgtgt ccttcatggt
    43981 cgtgggaatg gttatgttct gtcataagat tacctctttt cttttattat taaaataatt
    44041 gcttacctga gccgtctaaa taattttgta agatcatcac agctgctaat ttatcgatga
    44101 ctttttttcg tttggctctt gaagtatttg cctgctctac tagcatacgt tctgcctgaa
    44161 cagtggttaa tcgttcatct tgataatcaa ctggcaagga gaatagttct ttgatctttt
    44221 ctccgtatga catggaagct tctgcccttg gtccgatgga attgttcata tttttaggta
    44281 atccaactac aaaccggtct acttcatatt gtgctactaa ttccttcaac cgatcaaagc
    44341 caaactcttc ttctgcttca ttgatccgaa tgatctctac tccttgagct gtccagccaa
    44401 aggggtcact gatagcaaca cctactgtct tagaaccgac atccaagccc attactctca
    44461 taaattcact ccatgatttg agaggtagtc cttgacaatt acttccatga tctcatcgcg
    44521 ttcgtgacgg cgaatcaaat ttcgagcatc acgataacga ggaatgtagg ccgggtctcc
    44581 agaaagcaag tagccgacaa tctgattgat tggattgtag cctttttctt ccaaagcccg
    44641 ataaacaatc gctaatgttt cgctcacttc ttttttgcga ctatcgtcaa aaccaaaacg
    44701 tacggtttca tctgtaaaac ccatgattct acacctcttt cccgcaaggt aattccagct
    44761 taccttctac aaccttattt tactcgaaga aagggaaaac tacaaacaaa tattccaaac
    44821 ttccgaataa attaagaaac actatttgta tgtttttttc cttttttctg tagctttatc
    44881 aaaagtactc ttttcataaa gtatacgcta tatttctttg aatgtatgtt tttacacaat
    44941 tttttcataa tattcataaa aaattcgaat agctgctact aattttttgt ttttgttgct
    45001 tgtcctgtct cataattgat cgtgtagcca tcttgaacat tgtagataaa gacattgaat
    45061 tcaatttttt tgtcttcaat gctttctgct tccaattgca ctcccctggc taccagttca
    45121 ttcccctcaa aatgaggagt gacacggtag cgtacatgat gatttgtttc tttgatatat
    45181 gccgcaatat cattttcgtg agcaagcatg tatggagcat tcaacgaacg tgtccctgtc
    45241 atcaagtttt taatgttgtt attttgacca gtcagctgga aaccaattaa atggctgcga
    45301 ttatataacc attgcccgtc acttaatttc ttttgtttcc aacctgtcgg gtcaatatac
    45361 aaaggctctc tcttttcagt agggaacaaa tcttttccaa gcatagcatt ggcttgtcct
    45421 actctgttca atttatcaat atttgaatag ctttcccatg ttcctttgga aaggctaaga
    45481 tcctcttttg taaattccgg ctgattccca ttgatttcta tttcttgatg ttttccatca
    45541 tattctggca catccgctac ttgagaagct tgtggtgtgg aatcaaaaat agttgtaatc
    45601 tgctgaaaga tatctgaatc tttttgtgtg gtggaaacac cgaatgcccc tgcaatcaca
    45661 gcagcgacga tccccacgat cgccttggtt gtttttttgc tcatttcttt actcctttac
    45721 taacagctcc ctaaatctta acatatgttc ccctataaat aaatactaga aagaaataga
    45781 aacagcaaaa aataaaacct gttttaagat ggcttaaaaa tacaaaaaag agacggattc
    45841 ctcgtctcta atcagtcacc actctatctg taaggtattt attattattc aaaaattttc
    45901 ttcatactca agacaataca ctgatttcac aaccgcttgg taaacggtgc gcaaaagctt
    45961 gcatctgcgg taataagtcc atccaagtta aaaacataag aagttgtttt tgcttggctg
    46021 ttcttattac ttgttgcaga gcagcttttt cacaacctat tttaagcggg tgacgggaat
    46081 cgaacccgcg acatcagctt gggaagctgg gattttacca ctaaactaca cccgcaatac
    46141 aaaaacagta tacgcctctt ttattccttc ctcaagtttt tttattcttt acgcttctgg
    46201 tatgttttgt agtaaaataa aactaatcaa tcaattattg gagaagatgc tatgacggga
    46261 aaagaattag atctgttgct ggacacttgt ttactcgctg ggaaaatcat gatggaaagc
    46321 aatgcggaga tgtatcgggt agaagatacg atgagtcgaa ttgctttagc ttctggaaat
    46381 ttccgtttgg tcagctatgt cactcaaacc ggtctcttta ttggtcttga tcgtacctcg
    46441 accatccgaa tggaacaaat taccaaccgt tcgattaatt tagaaaaagt agtaaaagta
    46501 aatgatcttt cacgtaaata tgttgcttca gagctaacat tagaagaact ttactgcgaa
    46561 ctgcaagcaa tcgaccgaga ccgttctttc tttcctgtct ggttgcaaat cgttagcgcg
    46621 gcagtgatca gtggaacaat tatggtgtta tttggcggaa agatgaccga tttacctgtg
    46681 actttagtca ttggaggatt gggatacgca gcttatctat atagtttgaa attttttaga
    46741 atcaaatttt tatcggaatt tttatcttct ttattgattg gcatagccgc tatctacagc
    46801 gtacgttttg gcttaggaag caatcaggat ctaatcatta tcggatgtgt gatgccttta
    46861 gttcctggag ttcaaattac gaacgctatc cgtgatttgc tagctggaca ttatgtctca
    46921 ggagtttctc gcggaacaga agcgatgatg actgctacga tgatcggttt tgcgattgct
    46981 tttattttcc agctttttta ttaggaaagg aacacaagta tggggacgat atttattcag
    47041 ttttctttta gttttttagc gactgcggca tttgccgtta ttacaaatgt acctaggcgt
    47101 tcattgattt gttgtggtct ttctggtgct tttggctgga tgatctactg gatctgtgtt
    47161 caaataggcg gatctgctgc ttttggttca ttgcttggtt ctttaggagt agcattcatc
    47221 agcgatcttt tctctaaacg tttgaaaatg cccgtaacga ttttcaatat tcccgggatg
    47281 gttcctctag tccctggtgg tttagcttat caagcggttc gaaatctcgt tactgaatcc
    47341 tatcgagaag cggctcatta tgcggtccaa gcaattatga ttgctggagc aatcgcttta
    47401 ggtcttgtat tatcagaagt ctttaaccat aacatccgta atttcaaagt aaagcgtgac
    47461 gcaatcatga tgaaacgaaa aaaacggctt tttaaataaa cgaagtgtaa caaagaaaag
    47521 gttgtgaaag agacgttcag ccttgagcga tgacaaaata tctcacaaac attgcgacaa
    47581 gtaaccgcag gagcaataag aagtaattat gagtattaaa aaaagttttg taaaaatagc
    47641 ttctcacatt tttacataaa attgacttaa tactgagaaa ctgacttttg aacaccctct
    47701 atctgtaaaa aaggggctgc gacatgattt ttgtcacggc ccctcttctt tattcaaatt
    47761 ttttccaaaa cgttcgttga taataaacga tccatagagc ggaaagtatt agaactaaac
    47821 cgatcacagg aatattcact aaccaaaatg gataaaacaa agccaacatt ccgtataaga
    47881 cgataagaat aatactgatg atcaatgaac ccatcatagt tgcgactaaa cccaaacttc
    47941 ctgaacctct gttaaataat tggttaatat tggtccagtt cagcagcagc aaccgataat
    48001 ctctagcgaa ataacgtagt gacaataagt agcagccgaa taaagaacca aatagcaagc
    48061 tagggataaa aaacaaaggc agctgaaaag acagtccgct taataatgcg atcccaccag
    48121 ttaaaaaact ctgcaatatc catccgaatc tgaacttttc ttttaaatat tggttcatag
    48181 agattggcaa agaacggata aacagaaaat tttcttgatc caaagaaata agattgctga
    48241 taaaagaagt ctgattaact gttaagaaag ccaatgcgat ccctaccagg aaaacaacac
    48301 cgattaactt attatctaaa tcagttaatt ttatttcgcc tcctagggca aaagcaagaa
    48361 taaaaatgat tggagttaac aaggaagaag aaagaacttg cataatcaaa ttaggttctt
    48421 ttactaattg agcattgtaa ctaaataaaa gctgatgcac attttggttc tttttatggg
    48481 ttctttttat tttgaactca ctgtttgaat cagtcagttg ctctgtaagc tttggtacta
    48541 tcagctgttt tacagcaagg aaaaatccca gagccgtgat agctagtatt ccccaaccca
    48601 ataaaccttg ttgagaaagt ggctgactgg cagcatcata gaatggcaat aatatcgaaa
    48661 tcggatgccg atctgttaac tcattttcaa tagtccccgt ttgatgattc atccacatga
    48721 ttccagcaaa tgcgatcagc atcgagctgc caagcaagat actagaaact gtttttctat
    48781 gttttttaaa cactgctgtt cgagccaaac caaaaacaat caaactagcc agacaaaaaa
    48841 gaataatcaa aaatagagaa aacaaaagga ttgagataat gatagtaagc aaaatcccta
    48901 gatcagctcg ccatccggtt aaaataaaca tgactagaag cggaaaaaca aaaggaatga
    48961 tggtcaaagc aactaccaaa atctttgctg aaaaaacctg ttcttgtcca aaaggcagag
    49021 gcaaaaatac ttgcaggtca tttccttcaa aaaagatatt ataaatgact gatatacttt
    49081 gagttaaacc taacatacca aaaagtgcca cgtaataagt aaagaaacct ggcaatttaa
    49141 caaagttcat agcaaacata gcaaatccgt aaatcagtaa aaaaatcagc cctgaaaaaa
    49201 gattttgaga caaaagatag atagttaatc gctttccctt ttttcctttc tctcttgctt
    49261 tattcgtgag ctgtggatta acatataaaa gattaactcg aattaattct aataattgtc
    49321 gcttatacat acggtccatc tcctgtcgct tgccttccag ccattttcaa ataaatcttt
    49381 tctagcgttt catcaggtga gccattcaat aattcactaa ctgccccctg ataaatcaat
    49441 tcacctttct tcaaaatagc cagtttatcg cataactgtt gtgcggtatc caatacatgt
    49501 gtagaaaaaa tgactgtttt tccttttgcg gcatgagcct tcatcatttc tttcaaatca
    49561 aatgctgctt gaggatcaag tccttgcaaa ggttcatcca atacccaaat atctggatct
    49621 ggcagcaacg tgccgatcaa aatcgttttt tgacgcattc catgtgaaaa acttgcgatt
    49681 gtttcatttt gatgactata catatcaaaa agcgctgtca attctgctaa acgcttttct
    49741 tttttttgtg tgtctaattc ataggcagct gaaatcaagt cccaatattc tccagccgtc
    49801 aattgtaaaa aaatatctgg ggaatcaggc acataaccga ttttttgttt gatactcaat
    49861 cgattttccg tcaatttcat tccatctact aaaatcgttc ccgatgatgg ttcaataata
    49921 ctaactaaac ttttaatcgt agttgatttt ccggcaccat tatgtcctaa aaatccaaaa
    49981 atttcccctt gtcttatcga gagagacaag tcttttaatg cttgtttttt cccgtaactt
    50041 ttacttacat tgatgaattc aatcatttct gtactccttt tgtttgttat tactttttat
    50101 tgtacccttc gttattggtg gagtaaatgt caaaaagagt gcataacaaa aaaggataga
    50161 aacgactagg ctgctacttg ggttgttctc ttctacagga aaacactctt ctaacaggta
    50221 agatatgagt ctttgttttc tttaaaatga ttcattttct atcttttctt gcataaaatt
    50281 ctttagttta tcaatacttc tctttcccat ctctagttgt tctccatttg caaatgttac
    50341 tatttcgttt actctgctaa tagatgtaat gttttcagta ttaatgatat aagcttttaa
    50401 atctttacat aaatactcat attcgagtga ttttttatat tttttaattg tgccgtttac
    50461 gagaatctct tcatctttca atactaggcc tattttattt ttataacctg gcatgctcat
    50521 tagataaagg atttcatcgt aatggatata gtgatcgcta ttaccataac ggacagttgt
    50581 ccaccttttt ttcgtagcat gttgaacagg atagttttct ttttctttca ataagtaact
    50641 ttggatgctt tttttatttt tttcataagt gaattctttt atcaaataac cactaggcgt
    50701 aatctttcga ttaataacag ttattgcttt attcggatga gacgttagat aaacaatttt
    50761 acacttttca ttcttttctc taagcatttc gcctagttcg ataccgctat aataggcgtt
    50821 caaatcgatg tctaggaaaa aaatatctga ggaatagatt tcattatttt taatgaattc
    50881 aacaaattgt ataacgttca atccctgaac gatctcaaat ttccaaggac ttaataaaat
    50941 tctggattct tccaaaattt ctactagcat tttttcaaaa accaaactat catccaaaat
    51001 aaatatacgc gttaccataa aaagtacctc cactcgatat tttactatca aaatcatttc
    51061 atacaacttt tcaacataca tgttaggaat aaattgtaat tctcttcaca atcttttcca
    51121 acacctttga aaccgatatc aaatactttc aggatgctgc ttctaaaata aatatcaaac
    51181 aaatgaatac atcatgcaaa aaaagccaga caaccgacgt ccttgcgtgt cagctgtctg
    51241 agctatgttt atttattttg ttcttttaaa aagaacgata cacatactga tttttcggag
    51301 cagagacttt ctcagcgttt gtaacaacta cagatgggat ttcacgcttg aatggttgat
    51361 aatagtctga ttggatggtt ccttctattt tataccattc atcattttta accgttactc
    51421 cttccggcat atgcgtcaac aaaccaaaga ctcctgaatc tgccacacaa tggataatgc
    51481 cgaatcggaa caagaagata tctgtattgc tatcgttcgg tgtttggtaa acaaatcctt
    51541 catagctgat ttttttgcca atgaattcgc tagggtaatt ataaattagc tccataactt
    51601 ctaaatagtt ttcatctgtg atcttgatag tttgcttatc cccatacttt tctttcaact
    51661 cattcatttg gtctaagtag tctgatttgt tgaaataaat actggtatcc ggctttaagt
    51721 attgtgtctg catctccgga tcccctactg attctttact tactgggaaa ttaaatcctt
    51781 tggcttctac gatcgtagtg tcgagactaa ctgttggaaa caacgtcccc acgattactg
    51841 gcaaagctag cagtacataa gcgattccac gttgataagg ttttgacaac ccatggtcat
    51901 gatcgtgctc gtgtgccttt tcttctgctt ttccgttttt gacccacaaa tacagctgaa
    51961 ctaaagccaa aagagcagat aaaatcattg aaagaatagc taagtagcga taatggacat
    52021 tgatatattg atcgagtttg ccagaaactt gcaagtacat catcaattcg aaatacccag
    52081 ataaaatcaa aaaccgcagc atattttccc tcctaaataa ataatgtgaa tccaataacg
    52141 ctaagggcaa tcagtccgat cagcgataaa ataaagcgtc ctgtaaaata tcgtttcatc
    52201 atcagtagat ttttgatatc gaccattggg ccaaagacca aaaaggcagc tacaggtgct
    52261 gtgccgaaca gacttaacaa agaagatcct ataaacgcat ctgcttctga gcaaagagac
    52321 atcgtaaagg ccaataacag catgatgata atggctaaaa tctttgttga gccgagcgtt
    52381 agcataattc tagttggtaa ataagtctgc atcgcagctg cgattaatcc gccaatgatc
    52441 aaataacgac ctgtatcaaa aaattcgtcg attgaatgtg tcaacacatg cccagtttga
    52501 tggatcagct gattttttgg ttcattcttc tcactttgtt cttcttcatg gacatgatga
    52561 tggtgatttt ctgctacttt agacgtgatt ttttctttca atacagcgtc tttttgaaaa
    52621 taggcaagcc agacaccaat cacaagggca acaaaaaagc tgcctatcac ccgccagctt
    52681 gccatctgcc aagaattgcc aaatgcgata aaagtggaaa aaatcacgat tggattgatg
    52741 atcggagcag tcagcataaa agcaaacgct gtgtgaactg gtacgccttt tttaacaaat
    52801 tgatgaacga tcggtacgat gccgcattca catgaaggaa agaaaaatcc taagatcgaa
    52861 ccagtaaaaa tagagaagat acgattttca ggaagccatc tcttcacacg ttctggggtc
    52921 aaaaatactt gtaaggcgcc tgagataaga cagcctaata atacgaaagg taatgcttca
    52981 ataacgatcg ataagaaaat cgtactcatc tgcaaaaccg aatttggaat aaaagaaaac
    53041 atgagtttcc tcctttttat ttctagttca ttcgctttgc aaatatacgc ttttattcaa
    53101 aaaaaacaag ttgctctgta aatttttaca caactcttat tttttaccaa agcacttcaa
    53161 ttgacttttt ctgttattcc cattaaatta aggtctcata catatcactt ctatcataaa
    53221 agggagaata aaaatgaaac aaaccactaa cttgactgaa gttcaagaca tactgcaaca
    53281 gtcatccgtt gccgtcattt atctttcgat gcctaattgc agtgtttgtc acgctgttcg
    53341 tccacgacta gaggaacttc tcacacatta tgatattccg gcacttcatt tggatgcatt
    53401 tgaaacacca gaagtagcta gtaaatttga agtgctgact gcgccagttg tcctgatttt
    53461 tcatcaagga aaagaagtct ttcggcaagc acggttcatc gactttaaaa aaatccgtta
    53521 tctactagat gaactgacag cagaagatga ttccctttct tatgaagaaa tcttccgaac
    53581 aaaataatcg ttgtccaaac agaaaaaagc gattgaacaa gtgaaagttt tgccttcatt
    53641 tgttcaatcg ctttttattt ttattctgct gtattttcgg aatgcgcatt tgcgtcagaa
    53701 tgcaagaaat agatcaaggt ttgcaattca ttcgtcaaat caacattttg gatcaataca
    53761 tctgacggag cattcaatcg agcagcggta aagttcaaga ttcctttgat tcctgcttcc
    53821 gttaactgat tgactacttc ttgtgctctt tcagcgggta tcgttaaaat tgctacttcg
    53881 atttgttgga tcttgatttg ttctgacata tcttccattg gataaacggg gataccgtct
    53941 acgatgcgcc caacgatttc ctcattcaca tcaaaagcac aactgatacg tatgctatta
    54001 ctttgatgga atttgtattt tagtaaagca cttcccaagt tccctacacc gatcagcgca
    54061 acatttgtca attgatcgtc gtttaatgtc tttgcaaaaa agtgcataag atcttctaca
    54121 tcataaccat acccacgttt tcctaattcg ccaaaataag aaaaatctcg acggatcgtt
    54181 gcactatcta cttgaacggc ttcacttaat tcagttgaag acactttttt ctttccagca
    54241 ttatttaaaa tccttaaata gcgataatac aaaggcagtc ttttagctgt cgcctttgga
    54301 ataatatgat ctttcacgaa atgacctcca cgtattgtct aattacatct ttgatttctc
    54361 catcatagca gtatttatag gaaaaaatca attccattgc tcagatattg tgaaatttta
    54421 ttctttattc atttatttat catttctgca aatctcgcag tataatggaa tttatggtag
    54481 actactaatt gaaaaatagt tttttatttg aggagaattc acaaagtaga aaagaggatt
    54541 ccatgatatt attacaagcc aatcagattg ctcgccattt tggtgcagaa gtcttatttg
    54601 aaaacataca tttagaaatc agtacaggcg ctcgtgtcgc tttagttggc agaaatggcg
    54661 ctggaaaatc gactttatta aagatcattg ctggaattga agcacctgat gaaggaaaga
    54721 tcgctaaaaa taaaacagcg actctcggat acctcgctca ggacacagga cttgattcca
    54781 atgaaacagt ttggaacgag atgctgaaag cttttgaaca agttagacaa atggaagagc
    54841 ggatgcgcga gctagagatt ttcattagcg aaggtacgcc agacacacct gcttatagtt
    54901 cttatttaaa agaatacgac cggctgcaac acgatttttc agatcgaaac ggctatggtt
    54961 atgaaaatga aattcgttcc gtattgcatg ggtttaaatt cgattcttca ttttatgatc
    55021 agaaaatcga tactttatca ggcggacagc gcacacgttt agctttagct cgcatgcttt
    55081 tgcaacaccc tgacattttg attctagatg aaccaacgaa ccatttagat atcgagacac
    55141 tttcctggct tgagaattat ctgcaaagct atactggtgc attattgatt gtttcccatg
    55201 accgttattt tttagataaa gtagtcaatg aagtctatga attaagcaga agaaaaatgc
    55261 gccattacaa aggtaactat tcgaaatatc tagatttgaa agcagaacag ttagcaagtg
    55321 aatggaaggc ttatgaaaag cagcaaacag aaatccataa attagaagac ttcgttgctc
    55381 ggaaccttgt tcgcgcctct accacaaaac gagcgcaaag ccgcagaaag acattagaaa
    55441 aaatggaccg gctggatcgt cctcaagggg atgaaaaaca agcaaacttt ctattcagta
    55501 tagaaaagcc ttctggaaat gtagtcttgc aaatcgaaga tgccgctatc ggatatgata
    55561 atgtcacctt atctgaacca atcaatctag atatccgtcg tcaagaagcg attgctctag
    55621 taggtccgaa tggtatcggg aaatcgacgt tgctgaaatc aatcattcac cagatccctt
    55681 ttatccgtgg aaaagaaacg ctagggacaa atgtcaccat cggctattac gatcaaggtc
    55741 aagctgatct gcatacaaac aagacgatcc tagcagaatt gtgggatgag catcctacca
    55801 ctccagaaaa agagatccga agtgctttag gtgctttctt attttctggc gaagatgtag
    55861 aaaaaccaat ccctctgcta agtggcggtg aaaaagcacg ggttgcttta gccaagttag
    55921 cgatgaacaa agaaaatttt ttgattttgg atgaaccaac aaaccattta gatattgaca
    55981 acaaagaagt attagaaaat gcattgatcg attatgacgg cacactgctt tttgtttccc
    56041 atgaccgata tttcatcaat cggatcgcga caaaagtcgt cgaactctct gaaaatggca
    56101 gcaaagtcta tctaggagac tatgattatt atttagagaa aaagcaggaa gaagaagaaa
    56161 tcgccgaatt gttggcacaa gatgagccag aatctgctcc tgctcccacg aacaaatctg
    56221 attattacca aagcaaagaa cagcaaaagc ttatccgtag ccttcaacga aaaattactc
    56281 aggttgaaga agaaatggcg cggatcgatg aatggatcga tcagttggaa caagaaatgg
    56341 tcgcgccaga aaacctggaa gatcacgtaa aactcaatga gctgaaccaa gatttagaag
    56401 ctgctagaca agatcaagaa acaaaattga cggaatggga agaactaagc ttggaattag
    56461 aagaatatga aaattaacga aaaaaccaaa acagaaacca ttcatgctgt tttggttttt
    56521 ctttttttat tttatcaaac aaaaattcca tatttacctt tttcaccaat aagaagacca
    56581 attactagtc attctcacta aagcttctaa ataatagtaa tcaccccaaa tacaaggtgt
    56641 atttacccca ttatttttgg gcttattata aacagactgt gttaaaaagc catcttcttc
    56701 ttccgttgta gcatatcttt ctttcaattg tcgcataatt ttccaaacag cagactggta
    56761 taagttcttt tctgttttgt ctaatagacc tgattctatt aattctaata atccacaaac
    56821 catgatcacc atactagatg tatctttttc ttctctgcta gaatcatcaa agatcaaatc
    56881 ccaataacaa atggtatctt ctggcaaccg attcataaaa taattggcta atattttgct
    56941 taaatcaaaa tatttttgtt ctttcaaata acgataactt aatgcaaaac cgtaaatccc
    57001 ccatgcttgg cctctagccc aacaggaatt atcactataa ccttgatgcg tacttccata
    57061 tcttggtttt ccatctttga catccatata aaatgtatga taagttgaac catcttctct
    57121 tactaaataa tctgctgcat tttgaatatg agcctgagca gcttttttat atttttgatt
    57181 tccagtttct tcactcgccc aatacaataa tggaagattc atgcaacaat ccatgatcat
    57241 tctaccttgt tgtgaaggat cactaggatc tccccaagct tgtataactc ctgccttctc
    57301 ccaaaaacgc tgaagtaatg tttctgcagc atcaattgaa gcttccttca tttttcgatt
    57361 tcccgttatt ttataatctg ctacggttga taaagaatac aaaaaaccaa gatcgtgatg
    57421 attagtgata atttgacagt caatcctgtg gataaaatct atatctgctt tttcagctgt
    57481 ttgttgaaat aaaggatcac ccgtcttctc aaataacaac caattaattc ctgtccaaaa
    57541 tccttctgtc caaccaatat tgtctcttaa tggataacgt ccttttatag gacactcgct
    57601 tgggaattga tactgactgt tactgatacg tttgattaac ctctccgtgt gtctgcgaca
    57661 acgctcgatc tcattattcc attctttttc cattaattct ttataacatt catttatcca
    57721 tttttctgga tgtattatct cttcaaacat cactttatca agcatttccc caccagcctt
    57781 tagcataatt ttagtctttt tttattgttt ttattttgga tagttagccc ggttgtccca
    57841 tcaaaatcaa ttttgggacg attgttccat acttctaaac tataatcccg atcttgatga
    57901 gcaaccactc ctgttccgag ccaatgggtt ccttttccaa atgtaccctc taatccagga
    57961 ataaaagtgt tttcccatgt catcaagttt gtattgggca aacccataat agctgtggat
    58021 tttcgtttaa tagtatcgtc acttaaacag ataatacctg aaaagccagc ttcactcacc
    58081 ctatagtttt ccttgtcttc ttctatgatt attccttctt tctcaggaga acattcaata
    58141 gcaaaccctg tctcatatag aacatattct gtatctaatt ctactttgtg tacgcgaatc
    58201 tgccagcctt caaaaggaat aagccaagtt ctgatttttg cctgtaaagt aggttcccat
    58261 gtagaggcaa gtacctcttt cttacataca atgtctcgta cattatttcg aacgatgaac
    58321 tgtccatagg ttttgatgct ctcattctta aaactggtcg tgatatatgt gtccgctcgc
    58381 tgaatcccta gcattgaatc cattgccatt tctgctttca attgattcgc tcgcggtatc
    58441 gaaaaaccaa attgactaga ataagcaaat tttaaatatt tttcattggt caatgtatgg
    58501 aaatttggcc ctaattgtcc cgcattcaaa aaaaatgtat gtccattatc atgttgtatg
    58561 agcaaattgg cttctgaaag aagtttagtt ccttcacgaa taggcatagg catttcttta
    58621 gccgtccaat actcatggtc ttcaggtagc gccaacaata aaaaaatctt attcagccat
    58681 aatggagata acgtactatt atagggttca gtcaatgtca attgagggta ggtataacca
    58741 atattcagga tacctttttc atcaaatatt tctttttgca tccaccatct tatattccga
    58801 ttgactaacc ccttgatttc acctaattta aaaggcaaaa gatcggccca caacatagct
    58861 gaccaaaagc ttgaaactgc aaaacgataa atcatgcttc gaccaaaagg cacatttgca
    58921 ccatcttccg caaaaaaatg aatatagtct ctagaaaaat caatagctcg gttcttatat
    58981 atctggctaa tgggcttttc tggttctagt acgctataaa tcaaaccata ataatgaaat
    59041 gcaaaaggat tataataatc ttggcgacct cttgaactgt ctcgatacca gccattttga
    59101 agataacaat tttctatatt atcaaatgct tctttcagtg ctgattcttt aactggataa
    59161 ccaaattttt ggataattgt tccgacaatt atcttaaaaa attgccaatt accatctgca
    59221 cattcatatt caaaaatttg cgagaaccaa tgaataatct ggcttttttc tcctgtatct
    59281 aattttttcc ataataattg ttcatgatga tataacgcta ataacattgc gggcatttct
    59341 accatacgct ggtctctttc atgtatttct ccccaataat cgggatggga aggatctgtt
    59401 ccagctttta ttcctgatag aattaatttc aaccatcgtt catctaattg gtcaattgcg
    59461 ggccccgctc cccataaaac ccgagagaat ccttccattc ctgcaatttt atttccatat
    59521 cctacccctt gatgtatata atcaatttgt gcgccacttg ctcgataaaa cggctggagt
    59581 ggttgattta tctttttaaa taagtcaaag taatcctgtc tggtccttaa tagtggtact
    59641 ggatgtttca ttgtattttc tcctcttttt actaccaaat agctaattcc gactgttcta
    59701 atcgaagtaa gccttcaata aaaaaataat cagaatagat cagtggcaca ttataagtca
    59761 gttctctatg gtatgcttct gctccgcctc caatgatccc atcttcatcc atattccaat
    59821 ttgcatagtg cttttctgtc ttttggagta tattgatagc agcttcatga tacatttttg
    59881 atcgtacaga ggaaacatat cctgctaatt ccagaagacc gcatgcagcg catactccag
    59941 cactggtatc aatattcgaa tcttttacag caaaatcaat gagaggaata taaccagttt
    60001 tttcgatttt ctgaataaaa tttactgcta tcttttctgc tatagctaga tagtacggat
    60061 tttttgtgta acgataactt aacgcgaatc catataaagc ccatgcattt cctctgctcc
    60121 aacaagaatt ctcattgtat ccttgcccgc caagtaaccg aatatatttc cctgattctg
    60181 catcaaattc tgcgatatgc ccggttgatc catctttcct cactagatac ttagctgttg
    60241 tatctgcatg ctgccgagca attttagaga acctcggatc accagtttcc ctcgaagccc
    60301 aatacagtaa tggtaaattc atcatactat caataatcat ccaaccaggt ttatggtcat
    60361 tccatgctac taaatagttc cctgaaatat tatagcgtcc agcaagtacc gtagctgcat
    60421 gtaaccctag ttgtcgacta tgtttgtttt gagactgttg ataatgtgca atagccgatg
    60481 gtaagaataa aaaacctaca tcatgatgaa cgtctgaaaa atggtacagg gcagattcta
    60541 ataattgttc ttgttgtatt gctgcctctt tgaacttttc tcgttttgtc ttgtgaaaga
    60601 gctgccataa aataccactc caaaaaccat tggtccacca gtcgattcct ctgtccttta
    60661 ttacgtctgt atattttccg ttgtaagaaa tatatggaat tttattcccc attctgtcta
    60721 attccgcatc tatcttttca gaagctacat tcaaaatttt tcttgaccat tccttcgtct
    60781 gttcattcat ggatatcccg ccattctttt aatttttatg aatgtggagt tgctcctaga
    60841 acgaactaga tggttaacat tcgttatttt ttttacttat ttgcagctcc aatgtcattc
    60901 tccttaaatt tagactgcgc ccacacataa atcaagacca ttgggatcac tgaagttgct
    60961 aaaattagca taattgcgcc ataattaatt ggctcacctg tactagaaac cgtcatattt
    61021 ttgataatta agggaaccgt atatttatct ttatctgaaa gcatgactaa tggaaataga
    61081 tattgattcc aacttcccat aaagataagt aaaccactag taataatcgt aggtgataaa
    61141 atcggtacag cgattttcgt aaaaatcacc cactcattgg caccatcgat tctggcagcc
    61201 tccatcagtg ctgtaggaaa ttgactgcta tattgtcgca tcataaacac tgaagttgta
    61261 ctggcaatcg aagggatgat cacacctgca taagtattcg ataatcctaa acgactcata
    61321 atgtaaaata aaggaatcaa tgtggtaaaa aaaggcacca tcctagatag cataactgta
    61381 ttgaacaaca gtttattccc cataaaacga tactttgcta atgcataacc cgccattgta
    61441 gaactggctg tagctaaaac tgtactgatt acagcaataa caatcgaatt ccaaataatc
    61501 aagggataat tatatctcgc catgatggct tgccagtttt ttaatagcat atccccaaac
    61561 ttgaaattga ttccgccact taaaatttct tgattacttt gcgttgaagc tacaatcata
    61621 tataaatatg gcatcaaaaa tattaaggca ccaaacacaa taatgacgta cgtaaaaatt
    61681 ctgctttgta tcttttgttt agtcattttt atcacctccg aatttaaatt gaatagccga
    61741 taatataaca gatacaaaca ccatcgtcca ggcaatagca gaggcttttc caaaatcaac
    61801 catttcaaaa cttgttttat ataaattgac tcctacgacc aaagctgaat tttctggtcc
    61861 attggaagtc ccaaagaata tatttgggat attgaaatta cccaagccat tgatagtggc
    61921 taaaactgtg gccattaaaa tgattggctt tagcatgggg atcgttaata aaaagaattg
    61981 ccgaaatttc gatgctccat ctatttcagc actttcgtat atctctttag aaatcccttg
    62041 aagaccagct aaaaataaaa tagtgttata tcctacacta agccaaatca tcgtgatgat
    62101 cattgatatt cgtatccaaa aaggatttgt taaccactgt acaccgttaa ttcctagcgc
    62161 attcaaaaat ccattgaata acccagtcgg attgaaaaaa gtcatgaata cggaagctac
    62221 agccaccgtt gatgtaatgg ttggaatata atagacagtt ctaaaaaatc cttttccttt
    62281 taactgtgct gaattcaata aaacagcaaa gtaaatagct aatagcatcg ttattggaat
    62341 tgatcctgcc atgataatca aaacattcgt gtaagattta ataaacaatg gatctcggaa
    62401 gatagctaga taattgtcaa atccaacaaa ttcaaatgag tagccaattt tcataaaact
    62461 aaaagcaaac gagataatga tgggaatcaa aatcgtcaca ataaagaaaa taacaaaagg
    62521 tgtgaccaat ccataagcac tttttttatg agacgtatct gttgcttttt tcttgctgtt
    62581 ctttattgtc ttgcttggta acgaagattg catcatcgtt aagtcctcct aatatttttt
    62641 aatcaccagt taattttacg ccgtacttat gagcaaaatt ttctgcttct tttagatatg
    62701 aattttcaaa atcacctgtt tgccaatagt tatatgcagc ggtagtcaaa taagacgtag
    62761 catctgaata agtggctggt aaaacagtat ttgatgtatt ttcattgatt ttattcaata
    62821 gttcatagta tttttgtcct ccttagtagt caaacttttt ctcagctgct tctgtttgat
    62881 aggccaatga gttagatgta gccacgccca gctccagtgc gttggctaag cattcttcat
    62941 ctgtcagcat aaatgtaaga aattgttgtg ccacttgtgg atttttggca tctttaggga
    63001 cataaaaact tgatcctcct gatactgcac cttttcctgg attttctttt gaaaaaggaa
    63061 tcagtggagc catgcgccat ttgtcagatg catcaggaaa attcaaagac atattcgtag
    63121 cataccagcc gccagcaaca aacattgcag attcttgaaa tgctttctca gcatcttgtg
    63181 caccgtagaa atgtacaata tctgagtcga tcatttcttt gattaacttt gcagcatgtt
    63241 tcgcttcttt agtattcaga cggatatttc cttcttcatc aagcaaagat tgattctgct
    63301 gggctagcat gttgataaac aattcttggt ccccagattc tggcaaggca attccaaaac
    63361 taccagtttt ttcttttaat gcttttgcca cctggatata ttcttcccaa gaactgattt
    63421 cttcaaaatc tacacctatt tcagcaaatt tttttggttg ataataacaa agtgctgggg
    63481 taaaatcact agcccaagga ataatcgttt cattactcgt ttgttgacgc aaaatattca
    63541 atttttgatc ataaaactga tcgccatatt tgtcataaaa tccatattca tcagcactat
    63601 aaaaagcatc ttgaaatttt tccagcacac ctgctgctga agtgtctgcc atggagataa
    63661 tatccggcat atcttcgtgt gttaccaatt ttggggtgat catttgtact gttgctgttc
    63721 ccgaagctac attcacaatt tttaagtcaa tatttgctcc agttttgcgg ttatagattt
    63781 ttgcagcatt ttcaacatag tttgtcagtt tgccgtttgc gacatatact tctaatgtag
    63841 tggctttttt tatcattgga tctgcgatgt ttgctgttac ttcttcgtta gtttttccac
    63901 atgcacttaa gctgaataat agggtaatgt ttagcaaagc tatcaccaat ttgtatcttt
    63961 ttttcatgtc tatcccttct ttcttttcaa gttcttatat aaaacgcttt cacttatgta
    64021 tattaacgga attagtaaca caaatattta tataaaaaaa tattttactt gtcgttttgg
    64081 cttttcattt ttgttataat agtcattaat tataaataga aagcttttta tataaaaaga
    64141 gaaaggaaag tggttctttt gttaacaaac aaccaatcct ccaatcttgt caaaaaaaca
    64201 ctaacctatt ccatagatac ccatcttcat ttatctgctg ctccctattt tcgactacta
    64261 ataaatgaaa gcgctaattt atatgctgaa tttgcacata aatctataga actagataat
    64321 ccttcccttt tattcattga taaacagcaa gaagtccaaa tcttttctac tcaaaaggaa
    64381 acacaaactt ttatcattat ccagttttat tttgatgagc aattattagc acatattacg
    64441 ggacaatctt tttctataga tcaagaaata acatctatca ttacttttct gaaaaatgaa
    64501 cagttcaaaa ttgattatct aaaacatagt aagccagcta tttcctatga tcaggaaatc
    64561 aattcttttt tcatactatg ccaacagatg agcattcatt tgctttcctt attagttact
    64621 tattgtctgc aaaaaattca attgtcttcc ttaccaaggc attatcaaca ggaacttgct
    64681 ttattgacaa taccttcaaa tgagaaagtc attcctaaaa aaaagcatat tctttattca
    64741 gatgaattag ttgatccaat catacgatat ttagaagaac atctttcaga aaattttttg
    64801 cttgaacaat tagcccaaat tttttttatc agtccagcca gcttaaaaaa acattttaga
    64861 aaagtgaatg gaaaaagtgt tattagctat tttaaagaac taaaaatgga aaaagcaaaa
    64921 cgtctcgtgc tagaaaatga attaacctat acagaaattg cagatatatt aggatttcat
    64981 tcgatccatc atttttcttc agcttttaaa aaatatacag ggttatcccc ttcaaagtat
    65041 tatctatcct taaaatagaa aaaaattttt aggttttatc cacaaattat ttctctatat
    65101 tttctgtcta ttcaaaataa acaataattt tccggcacaa ttatttgctg ttttttacca
    65161 taacatagta cgatcaacgt agaaaaggag atgtttttat gaaagttgtt gtcattggcg
    65221 gtgtagctgg cggtccttca tttgccactc gtttccgtcg attgaatgaa gcgcacgaaa
    65281 tcattatcta tgaacgcgga gaaaatattt cttatgcaag ttgtgctttg ccttattatt
    65341 taggaggtgt gatcactgac cgtgactcgc tgatcgaacg tacaccagaa atattgaaaa
    65401 caaaaaacaa catcgatgtc tttactaaac acgaagtaac agcaatcgat ccttctacta
    65461 agcgattaac agttaaagac ctatccacaa atgaagaaat aaaaacagat tacgataagt
    65521 tgatcatctc ttctggtgct agaccagatt atccggatat tcccggagtt tttgaagcag
    65581 aaaacggctt tgtcctccgt agtgtgacgg atgcggatcg aatcaaatcg ttccttgaag
    65641 aaaaaaaacc acaacatgtc gtcattcttg gtgcaggtgt tatgggtctg gaattagctg
    65701 agaatttcaa gcatcgcggc ttagacgtga ctttaatcga tcaattgcca caagtcgctt
    65761 tcccttatga tccagaaatt gctaatttag tttatgacaa attgctgaaa gaaggattag
    65821 ccgttcattt agaaacaaga gttactgaga tccgtgataa aggtcgagaa atagtattat
    65881 cagatggctc cgtcctttct gctgatatgc taatttttgc tgttggtgtt tctccgaaga
    65941 atgaagtggt gaaagcaacc ggcatacaat tatcagatac aggtcagatc attgttgatg
    66001 accagttaca aaccaatctg ccggacatct atgcgattgg cgatattatc gaaacgacta
    66061 gtgtagtgac tggtcagccg atccaaagta tgctttccag tgcggccaat cgtcaaggac
    66121 atatgctggc agatatttta aatggtacgc ctatgcgcta tcgcggatat attggtgcag
    66181 gtgtcgcaaa aatctttgat catacagcaa gttatgcggg aatgacagaa catgaattaa
    66241 aagcatcagg cataacaaat tataaaactg tttttatcac tccctttgac catgcctatt
    66301 tctatccaga agctacaaga ttaaatctaa agctgatttt tgatgcagat agcggtcgta
    66361 ttttaggtgg acaagcattt ggagaaaaag gtgtcgataa acggatggga gaactttctg
    66421 tagcaatcac cggaaacttg acagtctttg atttgcctga tttggagttg ccttactctc
    66481 caccgtattc tactacccgt gacccgttga atatagctgg ttatgtcgca atcaatcaaa
    66541 tgacgaatat cgtagaaacg atcaaagcaa gtgatatacc cgaaaacgat ttgaaagaag
    66601 cgttcttttt agatatacgt gaacctaata aagcaccttc tggcagtatc tcggcaacaa
    66661 aaaatattcc aatgaatgag ttacgagatc gaatcaatga aatcccaaaa gataaaaaag
    66721 tttacattac tttcagaaga ggattgaata cttatacttc tgcccgaatc ttggcaggtt
    66781 tgggtatcaa agcgattttg attgaagaat aaaaaaacga ccgcggtggg tagccgcggt
    66841 ctaggagtta tttttacttg aggagtaaaa atgaaaaagt atatagggtt gttggttggt
    66901 atgtatatag aatagaagat aaatgtgaag aaattgtgca ttatttcttc acatttatta
    66961 ggttatagtt taagaaagtt taaacattgc gcaatttaat tattttagct gtttcttttc
    67021 ataaaaaaac atgttgtgac tctgagacaa atcatagtcc atagtgatgt ctctagagta
    67081 actacgccta atattacgag gcatcatatt aatctatcag cactagtacc taaactagca
    67141 tccctttcga atattttttc ttatataata aagtttgctt tcactcctct aatctcacca
    67201 aatcgactgg cttgcgttgt gtgatactag gaactgattg gtttagaacg acttttctat
    67261 tgtaatcata tttttcgcca tcctcgttgt cttctaatcc ttcaatgaat gatccctaat
    67321 gtgtgtatta aataatttaa tttttttgtt cctatttatt taa
//
LOCUS       DAIGTA010000008        62158 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.008, whole genome shotgun sequence.
ACCESSION   DAIGTA010000008 DAIGTA010000000
VERSION     DAIGTA010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.008"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(85..2238)
                     /locus_tag="NOB43_000524"
     CDS             complement(85..2238)
                     /locus_tag="NOB43_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCI0981418.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2633..3481)
                     /locus_tag="NOB43_000525"
     CDS             complement(2633..3481)
                     /locus_tag="NOB43_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0981419.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3705..5645)
                     /gene="thrS"
                     /locus_tag="NOB43_000526"
     CDS             complement(3705..5645)
                     /gene="thrS"
                     /locus_tag="NOB43_000526"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCI0981420.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5982..6161)
                     /locus_tag="NOB43_000527"
     CDS             complement(5982..6161)
                     /locus_tag="NOB43_000527"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HCI0981421.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6208..8031)
                     /gene="cadA"
                     /locus_tag="NOB43_000528"
     CDS             complement(6208..8031)
                     /gene="cadA"
                     /locus_tag="NOB43_000528"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI0981422.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8309..10588
                     /locus_tag="NOB43_000529"
     CDS             8309..10588
                     /locus_tag="NOB43_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0981423.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10681..11328)
                     /locus_tag="NOB43_000530"
     CDS             complement(10681..11328)
                     /locus_tag="NOB43_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981424.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11507..12226)
                     /locus_tag="NOB43_000531"
     CDS             complement(11507..12226)
                     /locus_tag="NOB43_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0981425.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12357..13508)
                     /locus_tag="NOB43_000532"
     CDS             complement(12357..13508)
                     /locus_tag="NOB43_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HCI0981426.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13725..14465)
                     /locus_tag="NOB43_000533"
     CDS             complement(13725..14465)
                     /locus_tag="NOB43_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0981427.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14469..14792)
                     /gene="rsfS"
                     /locus_tag="NOB43_000534"
     CDS             complement(14469..14792)
                     /gene="rsfS"
                     /locus_tag="NOB43_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCI0981428.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14849..15442)
                     /gene="yqeK"
                     /locus_tag="NOB43_000535"
     CDS             complement(14849..15442)
                     /gene="yqeK"
                     /locus_tag="NOB43_000535"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HCI0981429.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15426..16076)
                     /locus_tag="NOB43_000536"
     CDS             complement(15426..16076)
                     /locus_tag="NOB43_000536"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCI0981430.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16086..16397)
                     /gene="yhbY"
                     /locus_tag="NOB43_000537"
     CDS             complement(16086..16397)
                     /gene="yhbY"
                     /locus_tag="NOB43_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCI0981431.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16413..17522)
                     /gene="yqeH"
                     /locus_tag="NOB43_000538"
     CDS             complement(16413..17522)
                     /gene="yqeH"
                     /locus_tag="NOB43_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HCI0981432.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17519..18046)
                     /locus_tag="NOB43_000539"
     CDS             complement(17519..18046)
                     /locus_tag="NOB43_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HCI0981433.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18226..19011)
                     /locus_tag="NOB43_000540"
     CDS             complement(18226..19011)
                     /locus_tag="NOB43_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCI0981434.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(19004..19873)
                     /locus_tag="NOB43_000541"
     CDS             complement(19004..19873)
                     /locus_tag="NOB43_000541"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HCI0981435.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19874..21253)
                     /locus_tag="NOB43_000542"
     CDS             complement(19874..21253)
                     /locus_tag="NOB43_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCI0981436.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21261..21680)
                     /gene="fabZ"
                     /locus_tag="NOB43_000543"
     CDS             complement(21261..21680)
                     /gene="fabZ"
                     /locus_tag="NOB43_000543"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI0981437.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVAPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21705..22181)
                     /gene="accB"
                     /locus_tag="NOB43_000544"
     CDS             complement(21705..22181)
                     /gene="accB"
                     /locus_tag="NOB43_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCI0981438.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22184..23419)
                     /gene="fabF"
                     /locus_tag="NOB43_000545"
     CDS             complement(22184..23419)
                     /gene="fabF"
                     /locus_tag="NOB43_000545"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCI0981439.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23438..24175)
                     /gene="fabG"
                     /locus_tag="NOB43_000546"
     CDS             complement(23438..24175)
                     /gene="fabG"
                     /locus_tag="NOB43_000546"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HCI0981440.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24187..25104)
                     /gene="fabD"
                     /locus_tag="NOB43_000547"
     CDS             complement(24187..25104)
                     /gene="fabD"
                     /locus_tag="NOB43_000547"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI0981441.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25211..25435)
                     /locus_tag="NOB43_000548"
     CDS             complement(25211..25435)
                     /locus_tag="NOB43_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI0981442.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25488..26450)
                     /locus_tag="NOB43_000549"
     CDS             complement(25488..26450)
                     /locus_tag="NOB43_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HCI0981443.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26460..26900)
                     /locus_tag="NOB43_000550"
     CDS             complement(26460..26900)
                     /locus_tag="NOB43_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0981444.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27206..28171
                     /locus_tag="NOB43_000551"
     CDS             27206..28171
                     /locus_tag="NOB43_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI0981445.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRAQLPDLQ
                     EMTFEQKKKELQGLFQGQNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKHFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28228..28458)
                     /locus_tag="NOB43_000552"
     CDS             complement(28228..28458)
                     /locus_tag="NOB43_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HCI0981446.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28544..29431)
                     /locus_tag="NOB43_000553"
     CDS             complement(28544..29431)
                     /locus_tag="NOB43_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCI0981447.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29520..30743)
                     /locus_tag="NOB43_000554"
     CDS             complement(29520..30743)
                     /locus_tag="NOB43_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI0981448.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30760..31806)
                     /locus_tag="NOB43_000555"
     CDS             complement(30760..31806)
                     /locus_tag="NOB43_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI0981449.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYSIRVPIQAISNGIDLEKYRPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31970..33697)
                     /gene="ptsP"
                     /locus_tag="NOB43_000556"
     CDS             complement(31970..33697)
                     /gene="ptsP"
                     /locus_tag="NOB43_000556"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCI0981450.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(33697..33963)
                     /locus_tag="NOB43_000557"
     CDS             complement(33697..33963)
                     /locus_tag="NOB43_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HCI0981451.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34442..36676
                     /locus_tag="NOB43_000558"
     CDS             34442..36676
                     /locus_tag="NOB43_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0981452.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36824..37144
                     /locus_tag="NOB43_000559"
     CDS             36824..37144
                     /locus_tag="NOB43_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI0981453.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37349..37573)
                     /locus_tag="NOB43_000560"
     CDS             complement(37349..37573)
                     /locus_tag="NOB43_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HCI0981454.1"
                     /translation="METEWQIRERKKQKKEEMLRLCRLLDLKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37771..39351)
                     /locus_tag="NOB43_000561"
     CDS             complement(37771..39351)
                     /locus_tag="NOB43_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCI0981455.1"
                     /translation="MNNPELKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39752..41128)
                     /locus_tag="NOB43_000562"
     CDS             complement(39752..41128)
                     /locus_tag="NOB43_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI0981456.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41256..42374)
                     /locus_tag="NOB43_000563"
     CDS             complement(41256..42374)
                     /locus_tag="NOB43_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0981457.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42516..42796
                     /locus_tag="NOB43_000564"
                     /pseudo
     CDS             42516..42796
                     /locus_tag="NOB43_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(42874..43407)
                     /locus_tag="NOB43_000565"
     CDS             complement(42874..43407)
                     /locus_tag="NOB43_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HCI0981458.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43501..44679)
                     /gene="mutY"
                     /locus_tag="NOB43_000566"
     CDS             complement(43501..44679)
                     /gene="mutY"
                     /locus_tag="NOB43_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCI0981459.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44672..45469)
                     /gene="recX"
                     /locus_tag="NOB43_000567"
     CDS             complement(44672..45469)
                     /gene="recX"
                     /locus_tag="NOB43_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCI0981460.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNRGKSQKELLRKIQQTLMTKGFSQEVIQQAMADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45576..46958
                     /gene="rlmD"
                     /locus_tag="NOB43_000568"
     CDS             45576..46958
                     /gene="rlmD"
                     /locus_tag="NOB43_000568"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI0981461.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMICEINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47132..47710)
                     /locus_tag="NOB43_000569"
     CDS             complement(47132..47710)
                     /locus_tag="NOB43_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HCI0981462.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48032..48502
                     /locus_tag="NOB43_000570"
     CDS             48032..48502
                     /locus_tag="NOB43_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCI0981463.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48610..49836)
                     /locus_tag="NOB43_000571"
     CDS             complement(48610..49836)
                     /locus_tag="NOB43_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0981464.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50590..50790)
                     /locus_tag="NOB43_000572"
     CDS             complement(50590..50790)
                     /locus_tag="NOB43_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0981465.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(50924..51532)
                     /locus_tag="NOB43_000573"
     CDS             complement(50924..51532)
                     /locus_tag="NOB43_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HCI0981466.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51617..52087)
                     /locus_tag="NOB43_000574"
     CDS             complement(51617..52087)
                     /locus_tag="NOB43_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCI0981467.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52135..53049)
                     /locus_tag="NOB43_000575"
     CDS             complement(52135..53049)
                     /locus_tag="NOB43_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0981468.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53195..53998
                     /locus_tag="NOB43_000576"
     CDS             53195..53998
                     /locus_tag="NOB43_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HCI0981469.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            54176..55123
                     /locus_tag="NOB43_000577"
     CDS             54176..55123
                     /locus_tag="NOB43_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCI0981470.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(55191..55484)
                     /locus_tag="NOB43_000578"
     CDS             complement(55191..55484)
                     /locus_tag="NOB43_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HCI0981471.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(55512..56177)
                     /locus_tag="NOB43_000579"
     CDS             complement(55512..56177)
                     /locus_tag="NOB43_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HCI0981472.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(56317..56949)
                     /locus_tag="NOB43_000580"
     CDS             complement(56317..56949)
                     /locus_tag="NOB43_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0981473.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(56956..58023)
                     /locus_tag="NOB43_000581"
     CDS             complement(56956..58023)
                     /locus_tag="NOB43_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0981474.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(58020..58751)
                     /locus_tag="NOB43_000582"
     CDS             complement(58020..58751)
                     /locus_tag="NOB43_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HCI0981475.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(58919..59398)
                     /gene="greA"
                     /locus_tag="NOB43_000583"
     CDS             complement(58919..59398)
                     /gene="greA"
                     /locus_tag="NOB43_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCI0981476.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(59534..60709)
                     /gene="mltG"
                     /locus_tag="NOB43_000584"
     CDS             complement(59534..60709)
                     /gene="mltG"
                     /locus_tag="NOB43_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HCI0981477.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            60874..62034
                     /locus_tag="NOB43_000585"
     CDS             60874..62034
                     /locus_tag="NOB43_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI0981478.1"
                     /translation="MSKGKHRKKQKISISFLVILLLSVSFFSTGIIIGGQLTKIPHSQ
                     TYKAEPTQLTSNLTPDEQRLASKIDQLLQKSDYIGSIYVRKNNRVLLEKGYGYANLRV
                     KESNSPSIYYQIGSIQKAMTALLILKQIQAGKLTFDTKLAEFYPQIPGSQQITIKNML
                     YMRSGLHRTASPDKPMSDSEIIQFALHHLKLTDYDTYHYEPLNYTLLTGILIKLTNQP
                     YETLLKKEIIRPLHLEHTDFYDNVKNSPQHAVSYQMSATDDYSKALIEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGGIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVVAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVHLSN"
BASE COUNT        17928 a        13125 c        10479 g        20626 t
ORIGIN      
        1 aaatttaagc aaaaatgtga gaagctattt tcacaaaatt tttcttcata ctcgaaacta
       61 agcggctttt tcacgacctc ttttttattt tgccatgaac atatcataat acgcgtccat
      121 tatttcttta gcaatcgtca agtttatgtg gtcttgttcg tctaataagt tcggcaagac
      181 aacactgatg gcaatttccg gattgtctgt tggtccgtat gccacgatat tactattgac
      241 tgtcgcaata tctggatgac cttccgcaac cgtttctgca gtccctgttt ttgcggaaag
      301 gtccattttc gcactggcta atggtttggc tgttgtgtaa ggatcggtac catggacaac
      361 ttggtggaat ccttcacgga ggatcgccat attttctgca gaaatattga ccgtattttc
      421 tactgttgtg ccaatttctt tcttcacttc acccaagttt ccattttcgt cattgccata
      481 gatcgctttg actaggtgcg gctgtactcg tttcccgcca ttagcgactg ttgaagcata
      541 ttgagctaat tggattggtg tatatgtgtc aaactgtcca aatgccaaat cggtaaagtt
      601 acctggagca taccattctt tgccattatc cgcattgaac ttcttcatat aatcaacaga
      661 acgtgagatc ccaggagatt cattcggcaa atcgatccca gtcgttgtac caagaccaaa
      721 ctctttgaaa gagtctctca attgctgata agctttagct tcttcatcta aactaggtag
      781 tcccattcca ggtgtatagt ctagtcctaa catctttaac gccactttga tcatatacgt
      841 attagaagac aattccgatg ctttgactgc atcaagagca acttgtccgc ttcgattaaa
      901 gacagagctt ttttctgaag caccttgcag acgaatcggc tcatcaatca aaacttgatt
      961 tccgctgatc gcgttacttg cccagcctgc tgtcaaagta ccagccttga ctacagaccc
     1021 tggatcaaag gcgctagtaa tcgtgcctaa agcattctcg gtgatttctt tggaaccttg
     1081 ttcatgactg aaaccagtca ttgctagcac ttctcctgtc tgaggattca tagccactgc
     1141 ataagcacca ggcgaatact gtgctttgcc gttgttgatc aatgtttgat aattcctttt
     1201 caaaatttct tctacttttg attggaattc tgcattcata gataacatta aattagaacc
     1261 tttttcccca gagaagattt ctttttgatt cgaaacattt ccttcattat caagggaaac
     1321 ttcatattgg gttttggttc cttgcaggac atcttcatat tgtttttcca aataactttg
     1381 tcctacacgg tcattccgag aataaccttt tgctaggtat ttctctgctt catctgctgg
     1441 aagtccttgc ttttcagtcg tcacactgcc aagaatactt ttcagtgaac ttgctgcatt
     1501 atattctcgt gtccagtctg tgccagtcga aactcctgga agttcagaag cgcgttctgc
     1561 cacaacagct aactcttgat cagtaacacc agagtttttg atatagacag tgtttaattc
     1621 atatgcacta ttcatccgtt taaagatggt agcaattttt aattgctcct cgtttaaatt
     1681 aatctcatca gctgtgactt tattgaccat cgcactatat tgttcgctgt tccctaattg
     1741 cttttctttt gccgaaagtc tttttgtggc ttctttcaaa tgtttgggat cagccagcca
     1801 aaaatctttt ttatctctat ctgtcagatt ttcatctacc ggaacatcga tcagcgagtt
     1861 cagcttcgtt gcgatttcaa gcaaatcttt agccgtaact tgtgttcctc tcgtatatgt
     1921 gatggcctga ttcgctttat tcgtaactaa agcttttcct gtggagtcgt agatcattcc
     1981 gcgaggagta ctttcttgga ccgtaatcgt agaagtagac ttcactcgcg cctccatctc
     2041 ttcgccgttc acgatctgca aataacccaa tctagcaatc aacgcaacaa ataacgtaaa
     2101 tataatgaaa aaaagaaaat ttaagcgaaa aggaacatgg gaccggcgaa acgttttgtt
     2161 cttaggttct tgtgcacctt ttcttatttt ttctaaccaa gaagtattta atattttttt
     2221 cataaaatct ttcatcattt cctatccttc cgcctattta cattcatgct tcattgtacc
     2281 caaaaacttc ttaataaaca agaagtattt aatatttttt tcataaaatc tttcatcatt
     2341 tcctatcctt ccgcctattt acattcatgc ttcattgtac ccaaaaactt cttaataaaa
     2401 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
     2461 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
     2521 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
     2581 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
     2641 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
     2701 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
     2761 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
     2821 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
     2881 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
     2941 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
     3001 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
     3061 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
     3121 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
     3181 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
     3241 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
     3301 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
     3361 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     3421 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     3481 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     3541 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     3601 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     3661 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     3721 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     3781 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     3841 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     3901 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     3961 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     4021 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     4081 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     4141 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     4201 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     4261 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     4321 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     4381 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     4441 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     4501 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     4561 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     4621 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     4681 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     4741 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     4801 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     4861 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     4921 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     4981 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     5041 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     5101 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     5161 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     5221 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     5281 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     5341 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     5401 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     5461 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     5521 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     5581 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     5641 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     5701 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     5761 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     5821 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     5881 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     5941 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     6001 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     6061 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     6121 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     6181 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     6241 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     6301 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     6361 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     6421 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     6481 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     6541 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     6601 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     6661 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     6721 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     6781 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     6841 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     6901 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     6961 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     7021 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     7081 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     7141 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     7201 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     7261 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     7321 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     7381 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     7441 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     7501 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     7561 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     7621 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     7681 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     7741 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     7801 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     7861 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     7921 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     7981 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     8041 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     8101 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     8161 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     8221 ttcgattcat cagttaaaga gtaccttttt tcgaaaaact atgctatact tttaattcgt
     8281 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     8341 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     8401 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     8461 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     8521 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     8581 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     8641 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     8701 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     8761 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     8821 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     8881 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     8941 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     9001 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     9061 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     9121 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     9181 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     9241 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     9301 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     9361 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     9421 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     9481 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     9541 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     9601 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     9661 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     9721 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     9781 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     9841 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     9901 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     9961 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
    10021 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
    10081 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
    10141 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
    10201 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
    10261 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
    10321 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
    10381 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
    10441 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
    10501 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
    10561 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
    10621 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
    10681 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
    10741 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
    10801 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
    10861 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
    10921 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
    10981 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
    11041 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
    11101 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
    11161 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
    11221 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
    11281 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
    11341 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
    11401 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
    11461 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
    11521 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
    11581 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
    11641 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
    11701 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
    11761 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
    11821 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
    11881 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
    11941 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
    12001 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
    12061 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
    12121 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
    12181 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
    12241 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
    12301 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
    12361 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    12421 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    12481 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    12541 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    12601 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    12661 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    12721 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    12781 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    12841 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    12901 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    12961 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    13021 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    13081 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    13141 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    13201 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    13261 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    13321 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    13381 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    13441 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    13501 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    13561 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    13621 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    13681 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    13741 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    13801 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    13861 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    13921 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    13981 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    14041 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    14101 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    14161 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    14221 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    14281 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    14341 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    14401 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    14461 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    14521 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    14581 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    14641 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    14701 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    14761 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    14821 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    14881 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    14941 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    15001 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    15061 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    15121 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    15181 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    15241 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    15301 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    15361 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    15421 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    15481 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    15541 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    15601 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    15661 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    15721 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    15781 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    15841 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    15901 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    15961 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    16021 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    16081 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    16141 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    16201 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    16261 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    16321 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    16381 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    16441 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    16501 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    16561 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    16621 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    16681 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    16741 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    16801 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    16861 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    16921 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    16981 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    17041 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    17101 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    17161 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    17221 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    17281 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    17341 tcatccgtca atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga
    17401 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    17461 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    17521 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    17581 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    17641 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    17701 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    17761 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    17821 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    17881 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    17941 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    18001 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    18061 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    18121 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    18181 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    18241 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    18301 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    18361 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    18421 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    18481 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    18541 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    18601 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    18661 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    18721 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    18781 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    18841 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    18901 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    18961 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    19021 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    19081 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    19141 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    19201 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    19261 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    19321 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    19381 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    19441 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    19501 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    19561 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    19621 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    19681 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    19741 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    19801 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    19861 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    19921 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    19981 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    20041 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    20101 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    20161 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    20221 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    20281 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    20341 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    20401 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    20461 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    20521 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    20581 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    20641 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    20701 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    20761 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    20821 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    20881 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    20941 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    21001 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    21061 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    21121 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    21181 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    21241 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    21301 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    21361 tcaacttcaa ggtataaggt atctcccggt gcaactttct tacggaattt tgctttgtcc
    21421 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    21481 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    21541 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    21601 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    21661 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    21721 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    21781 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    21841 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    21901 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    21961 tctttttctt tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc
    22021 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    22081 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    22141 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    22201 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    22261 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    22321 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    22381 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    22441 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    22501 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    22561 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    22621 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    22681 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    22741 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    22801 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    22861 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    22921 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    22981 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    23041 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    23101 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    23161 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    23221 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    23281 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    23341 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    23401 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    23461 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    23521 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    23581 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    23641 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    23701 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    23761 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    23821 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    23881 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    23941 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    24001 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    24061 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    24121 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    24181 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    24241 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    24301 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    24361 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    24421 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    24481 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    24541 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    24601 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    24661 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    24721 cattttcccg cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa
    24781 cgcaactgct tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa
    24841 actcagtcct aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc
    24901 gatgctgact gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc
    24961 tgtaaagcaa agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg
    25021 ctttacaacg gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc
    25081 actaaataag aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt
    25141 cttcctattc aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta
    25201 attttaatga ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga
    25261 ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga
    25321 ataaatccaa gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt
    25381 cagtttcttt tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa
    25441 tatattcctc cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg
    25501 agaatacttc cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt
    25561 cctaaggtga tctttccact agaaactgct tcatccaata agatagggat gcttgcagca
    25621 gatgtattcc catatttatc catattggtc aggaactttt cttgcggcat ctttactttt
    25681 cgggcaattt tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt
    25741 ttgtctttca tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata
    25801 tctctgccag tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt
    25861 ttattttgct ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt
    25921 tctttcagca attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca
    25981 aacaacacag cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca
    26041 atcaccagtc ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa
    26101 acaaatcctg agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc
    26161 ccttgtactt gtgctgctac agatggcgtc gtgtaatcgg gcgacattgt tgctactaaa
    26221 ataaaatcca aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa
    26281 atgcataaat cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt
    26341 gacgaaatcc attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc
    26401 ttttcaggaa ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct
    26461 cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt
    26521 tcctccgtag ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg
    26581 acccgaaata gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct
    26641 tcactgcgga tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag
    26701 gtcccaacag taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc
    26761 ccgattgcct cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc
    26821 agctcagact cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact
    26881 gtttttaaat ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt
    26941 gatgttcaaa ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac
    27001 tatatgagct ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa
    27061 tttcttttat tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg
    27121 aacagaacta tagaattcct taaaacttgt ccattatttc aaaatttgtt atagtctttt
    27181 tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct
    27241 gccgggtgtc tatcttatga aagaccgtga tggtaaggtc atctatgttg gtaaagcaaa
    27301 acggctcaaa aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt
    27361 attacgtatg attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga
    27421 tgctttattg ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat
    27481 gaattatttc agtaattata attatgtaca tattaccaat aagggatttg tattaacaga
    27541 tactcctacg gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt
    27601 gcgtataatg gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt
    27661 gcgagcccag cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca
    27721 agggctgttt caaggccaaa ataaaaagct actaacttac ttgaaaaaaa gacaacaaca
    27781 tttcatctat cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt
    27841 tacttatttt attagacgga tccaggaaca aaagcatttt ttaagaacac catcgctcac
    27901 cttcagcatg ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg
    27961 tcaacttgca gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa
    28021 gaaagaagct catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca
    28081 aatcttgatc agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa
    28141 caaaaaagaa gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc
    28201 aacttcaaat gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac
    28261 gatatcgata ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt
    28321 atcggtcgct ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg
    28381 aacttgcagt tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac
    28441 taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa
    28501 gcatagccta cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg
    28561 gtatttttcc ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac
    28621 ctttatctgc caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat
    28681 ccattttttc tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa
    28741 aaccaggtgt gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag
    28801 ctgcacttcc acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg
    28861 catagacaag catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca
    28921 tttttgtatg ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt
    28981 tgaataaagg cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg
    29041 taccattctt tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt
    29101 tttcttttgc tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa
    29161 ctaaaatatg tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt
    29221 ctacatcttt ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt
    29281 ttggtgtatc tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc
    29341 gattatagac agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca
    29401 tgacgcctgt tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc
    29461 ttgcttctat gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt
    29521 tatcttttaa atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt
    29581 cttcgcatct cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg
    29641 ccgaaatgtg tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga
    29701 acttcactgg aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt
    29761 ttccctaatg aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa
    29821 ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca
    29881 ctgacaaaat aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct
    29941 gtgaactgca caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca
    30001 taaggtcctt ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga
    30061 aacccattaa tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc
    30121 atcaaatggt tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg
    30181 atatcagaac gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct
    30241 attacaccat agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc
    30301 gtatgatttg caaataatct agacaagtat tttacatggg attgcctgat cacttttcct
    30361 ttaccgatat aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt
    30421 ttcaacttct tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga
    30481 ataagatcta gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca
    30541 actcttcgat ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc
    30601 aacttatccg cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct
    30661 aattcttgtt ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta
    30721 tcggtaaaaa agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac
    30781 tttttttaat ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc
    30841 ttcaccgatt ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact
    30901 cggtagttct tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc
    30961 catatagcag ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag
    31021 tacgttttgt ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga
    31081 agggaaaaag aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta
    31141 accaggaaac aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg
    31201 aatcgagtac atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc
    31261 aatttctacg aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac
    31321 tttttgatcc ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg
    31381 gcgatatttc tctaagtcga tcccattgga aatagcttga atcggcacac ggatactata
    31441 gctttccaac aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta
    31501 caatcctacc agatattttt ttacgatagg agaaagctgg ttcgatccga taaaggaatt
    31561 tcggaaatct tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc
    31621 tttattgacc atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc
    31681 ttctttttca tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc
    31741 aagcgcacgc ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac
    31801 cttcacctta cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa
    31861 acttaagccc tatttttatc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa
    31921 aaaactggcg tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat
    31981 attcatgaac aagttcaacg acttcttcca tcgtatcgca ttctttcaat gcacgatcag
    32041 caagttcagc cattttcgct gtgtccaagc gtttcattaa actacgcgtt ttaagaatag
    32101 atgtcgcact cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt
    32161 gatctccagc catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa
    32221 ttacattttt gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc
    32281 gttcgttcat acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga
    32341 agaaatctac ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca
    32401 tgatgccgac ttggatcgta tcagatactt ccttgccttc actgatcaat ttttgttttt
    32461 cttcttcaaa gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca
    32521 tgatacgtaa gttaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca
    32581 tttcgtcgcc ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca
    32641 tttcatgagg taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa
    32701 caactacagg ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat
    32761 cttctgttgg gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg
    32821 cttctccacc attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta
    32881 attcaaaatg cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg
    32941 ctttttgtgc tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag
    33001 gatcgatgat tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt
    33061 tagcagtaat ttcttttgta ccaacgattg ctggaatttc taaagaacgt gccatgatag
    33121 cagaatgtga agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta
    33181 attgtgctgt atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca
    33241 ttgatggatt tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacatcac
    33301 gaatatctgc agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga
    33361 tatacatatc cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat
    33421 tttgcttgat ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata
    33481 cttgcgcttc tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt
    33541 cagtagattt agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg
    33601 ttgccttact gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac
    33661 cgtcactagc ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt
    33721 cattgtttca acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt
    33781 aacatcagaa ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac
    33841 tgatttacct ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa
    33901 tagtgtagct ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc
    33961 catattaatc ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt
    34021 aattcagaga atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg
    34081 ttagatacaa cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt
    34141 tttcatcctt ttcttcacat tttataacaa acgtgtttat tttctttttc ttgtcgcttt
    34201 ctcttctcct gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa
    34261 ttacttgctt ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata
    34321 gagatttcac cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct
    34381 catgaaaaac gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt
    34441 catgctttgt caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa
    34501 tggtcagcgg acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca
    34561 aaatggaggt ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga
    34621 tcttttccgt tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc
    34681 aacacaattt ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga
    34741 aggtttattg ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga
    34801 tcctgtgatc ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac
    34861 caagaacaat cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg
    34921 tttagcacaa aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat
    34981 tcgtttagat gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg
    35041 tatgcaaaaa ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga
    35101 agttcacgaa atcgtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat
    35161 tttaaaacca gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga
    35221 gtaccgcatc atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga
    35281 tgaaccaact gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga
    35341 ctatcatcat gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg
    35401 ttacgtccaa gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc
    35461 taagaaaaac ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga
    35521 agcagaagaa caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta
    35581 tcgcgatcag atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac
    35641 acctgtgatt accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt
    35701 gggtgaatta aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc
    35761 tcatgtcatc ggacaagata acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg
    35821 tgttggatta aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg
    35881 tgtaggtaaa acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc
    35941 aatgattcgt ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg
    36001 ttctcctcca ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag
    36061 aaatccttac agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca
    36121 tatgttcttg caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag
    36181 ctttaaagat acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa
    36241 cgttggtttt ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa
    36301 ctactttaca ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc
    36361 aaaagaaaac ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc
    36421 agcacagcaa cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg
    36481 ctatgatcca tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga
    36541 tggtatcgct gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga
    36601 taaagatgga aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga
    36661 agaaacggct gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg
    36721 tctcattctt ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat
    36781 aagagaaaca agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt
    36841 aacaaacagc cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt
    36901 caaggtctac acagccggaa ataccactat tgtctacact gaagcccctg aacataatga
    36961 aattctgctg atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa
    37021 ttatttctta gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga
    37081 attggcaggc cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt
    37141 gtaaacaaat tttgaacata ataattaaag agcgtgggac aaaagtaaag aacacttttg
    37201 tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg gaaataagct
    37261 aaaattcacg aaaattgctt ttcaaatttt tgtgaattcc agcttatttc ttggagttaa
    37321 acgcttctgt ctcagcctct ttttctttct agctttttga tttttctctt ttcttttgta
    37381 cttttctctt ttcattttca gttctacgcg tgtctttatt tttaactttt tcctctttat
    37441 ggatgattga tcgtactttt tgtgcaattt gctcgttttt gtcccagtct tttaaatcta
    37501 ataatcgaca taatcgtaac atctcttctt ttttctgttt ttttctttca cgtatttgcc
    37561 attctgtttc catgtgtcac actctccttt ctttaatcat atgtacgcaa aataattttt
    37621 atattttttt gattagacat ttctatgatt ttaatatagt aaaaagagcc gtcacggaaa
    37681 atccgtcacg gctctaaaca aaatatgaga gactgttttt gtttggctat tcttattact
    37741 tgatgcaggg cagcttgtgt caagacttct ttacatcaaa ctttttaatt ttacattagg
    37801 atatttatcc gcaaaccagc gttctgcaaa ttggttctcg aataagaaca atggttggtc
    37861 gaaacggtca cgagccaaga tattgcgact tgaactcatc ttctcatcca aatcttctgg
    37921 atcgatccag cgagcgattt tgtgtcccat tggagacatg attacttcgg cgttatactc
    37981 atttaacata cgatattgga atacttcgaa ttgtagctga ccaacagctc caatgatata
    38041 ttcttccgtt agatatgttt tataaagctg aatcgctcct tcttgaacta attgatagat
    38101 tcctttgtgg aaggattttt gtttcatgac attttttgca gtcactttca taaacagctc
    38161 tggagtaaat gaagggagtt cttcataagc aacttttagt tttccttcga acaatgtatc
    38221 cccaatctga taattgcctg tatcatatac accgatgata tcgcctgcta ctgctttttc
    38281 gacgttttct ctcgaatctg ccataaattg tgtgacattg cttaatttca gttttttatt
    38341 tgtacgttcc aaccagacat ccattcctcg ttcgaatgtt ccagaacaga ttcggacaaa
    38401 agcgattcgg tcacgatggg ctggattcat atttgcttgg atcttgaata cgaaacctga
    38461 aaattcttcc tcataaggac ttaccatctg atcatcttgt gttttgtgtc cataaggagc
    38521 tggtgccaat tcaacgaaag tctctaaaaa agtctgtaca ccgaagttag tcaatgcaga
    38581 accaaaaaat actggtgtct gatcgccacg agcaattttt tcttgattaa atgcatctcc
    38641 agcctctttg attagttcta cttcttctaa gacttgttca tataaggaat tttcagttag
    38701 aggatgattt tcgggaagca gtccatcttc atccaattct actaatcgtt catcctgata
    38761 attttccgga cgataaaact ctacacgatt atggtagata tcataaagac cttctagccc
    38821 tttacccata ccgattggcc aattcatcgg ataagattcg atatctaata gctcttctaa
    38881 ttcttctaac aattccaatg gttcacgacc atcacgatct agtttgttga taaaagtaaa
    38941 tatcgggatg ccacgttttt ttacaacttg gaataatttc tttgtctgtg cttcgatccc
    39001 ttttgcacta tcgattacca tgaccgcact atccacggcc atcaaagtac gataagtatc
    39061 ttcagaaaaa tcttcatgtc ctggtgtatc caagatattt actcgtttcc cttgataatc
    39121 aaactgcata acagaactag taacagaaat cccacgttgt ttctcgattt ccatccagtc
    39181 tgatttggca aaattacctg tttttttgcc ttttacggtc ccggcttgac ggatagcccc
    39241 accaaacaat agtaattgtt ctgtaatcgt tgttttccca gcatccggat gggaaatgat
    39301 cgcaaaagtt ctgcgattgt ccacttgttg ctttaattct ggattattca taacctaact
    39361 ccatttcttc cattcaatta tttatatttt ctctaggcac agattgtccg atctcttaaa
    39421 gaaagacaat ttcatatagg gctgtgacaa aagccgtgta gcagtctctt tttccgagta
    39481 aacggcgttc tagagacagc ctatcagcaa taagcccacc caagccaaaa atacgaaaag
    39541 ctgtttttgc ttggctgctc ttattactta atgcaggata gctttttcac aacctttgtc
    39601 aactactaca actgaatcag tatagcatgg attcatcgaa tgaaaaagcc accaaaccat
    39661 aagagtcaaa tatttttttg tcagctgact aaaagaaaag acgtgttgct tgtttattca
    39721 agcaacacgt ctttcataac caagtttcca attatcttct tggctcgtca tcttcgaatt
    39781 cttttctgaa gtatcttcgt tcttcttcag gttccgcttc tgtttcttcc ggatcatgaa
    39841 aaatgacacg gattttaagg attcgagaac cttccatttc ttcagaaacc agcgtaatat
    39901 tatcgacatc aaacgataac ttttcgcctt catccggaat catgcctaat gctgtaatca
    39961 aataaccagc catcgtatct acatcactca tatgcagatc actgtcaaaa gcttcattga
    40021 actcatcaat cagcatacgt ccttggatga tatattcgtg ttcatcgatt ttttcataaa
    40081 gattctcaac ttcatctgat tcatcatcga tttctccgac gatttcttct aaaaggtctt
    40141 ctagtgttgc taacccaacg acgccgccat attcatctaa taaaatagcc atctgattct
    40201 gcgtcttttt catttcatat aacagatcat caataaagac cgtttcagga acgaataaag
    40261 gctcctgcat gattttcttg atatctaaat tatcaaaacc gaatttatgg gcagctttta
    40321 gtaaattctt tgtatgaagg attccgacta ctttatcttt gtcttcgtta taaacaggga
    40381 ttcttgaata gttttcggat aaaacttcat tcacattttc ttccacagtg tcgttgatat
    40441 caatcataaa tgcatccgtt cgtgggacca tgacttctcg ggcaactttc gtatcaagag
    40501 aaaaaacccc ttggagcatt tctaattctt cattattcaa tacgccttcg ttttcaagca
    40561 tataacgcat ttcatctctg gtcatttttg aatcttcatc atcaaaagtc atcggcgtga
    40621 tacgcgccaa taaacttgtg gaagcagaaa gcagccagac gaagggctta gctactacac
    40681 caatcaagcg tatcagccct gaagtgaact ttgcgacttc ttctgattta tttaaagcaa
    40741 tacgtttagg gtacaattct ccaaaaacaa tcgatacata ggtcaaaata gccagcacaa
    40801 tgatatttgc aatatttttt gccgctgtgc cgccacctaa taccggagct aaccgttccg
    40861 ataaagtatt agctagtgaa gcaccagaca aaatgttgac caaagtgatt cctacttgga
    40921 ttgtcgatag gaaattattt ggattctgca atatttttaa aagcttttga gatttcacat
    40981 ctccttcatc agctttttgc tcgattcgat tcttattgat cgaaacaaca gcaatttcgg
    41041 aagctgctaa aaaagcattg atcaatgtca aaacgatcaa taataaaatc tgcgctaaca
    41101 gcgactgact ctcagggtca gcattcataa tcgcattctc tccttataaa attaattttt
    41161 agtttacgat agaaaaaaac gtggcactat agccacgtta aaatggtatc acaaagcaat
    41221 tttctttgca ataaaaacaa gtgtactaaa actacctacg aggtcgtagc aattttcttc
    41281 ttgttttcat tttgcttgtc ttctttgacg attttgatta tataggaaat gatcgtcttg
    41341 cagattgcgt aaaaaggaac acctaagaag ataccaagca atccggcaat atttccagct
    41401 actagaagaa cgataatgat cgttaatgga tggattttca gtgatttccc aattacatta
    41461 ggataaatga tattcccatc caactgttgg acgattagca caaccacaca acaaagtaat
    41521 gcttttaccg gatcattgaa gactgttact agaaatgcag gtgctagtcc tagataaggt
    41581 cctaaatatg gaattaggtt tgtcaatccc gcaatgaccc caaataagaa agcataatcc
    41641 acaccaatta ccatatatcc taaaaatgtg aaggtaccaa cgaataaaca ttcgattgct
    41701 tgtccgctaa tgtaattagc caatgtttta ttcagttgcc ccaataactc cacaatttgg
    41761 tttcttcttt tttctgggaa aaactgttgg atgtttggca ctagtttttc tccgtctttc
    41821 aacatataga acaagatgaa tggtgctgta atgattacta cggttgccga agcgatcgtt
    41881 ccaacgatcg aacctaaact attggatact ccactaagga attgctgaat gattgtcccg
    41941 taagaaatgt ctaattgctc aaaatattta ttgatatcta cttccttgaa caaaggcaat
    42001 tcggctacct cttttaacca gctttctacc tgtttgatga aatcaggcat attagatgcc
    42061 aatgaggaaa tttgctgtac tagacttggg atgacactaa gtaaaatcca aataattgct
    42121 gcaactaaaa ggagcagcac aattgcgaca gcccatattc ttttgatttt tgctttcatc
    42181 aacagcttga caataggatt caataaatag taaagaaagc ctgcaatcag tacaggtgca
    42241 aataacgtgg aaaaaaatgt cccgatcggt tcgaaaataa agtttatttc tgatgaaatc
    42301 atgatcaatg cagctatgat caataattca agcgaccaaa acattagttt agactgtcta
    42361 agtttttcaa acaatagatt tcctcctttc tttcttacta gtatatatta tattcgttaa
    42421 aaattctttt attctttttt tatttttgaa aacttgccat actttttatt tgttttattt
    42481 tccagtatac tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata
    42541 caatgagcaa tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac
    42601 agggtatgcc tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc
    42661 tgtactcaga taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa
    42721 aaatgaaatt acagcggatg gcgatccttt tgaagatgct ggcatgcctc atatttatat
    42781 gaaaaagact ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa
    42841 aatctctcac tggcttactg ttcttttttg tgtttactta cgcgacaatt gcttgtaacg
    42901 gttataccaa atatcaatat agccttccga gaacgggcca tctccattat tgatccagtc
    42961 aaccagaatc ttcacatttt cttttaggat gaagtcaata tcgttcggat aattcatcat
    43021 tttgctgtgc atctcatatt catcgacatc caatagtcgt ttctcgccgt caggaaatac
    43081 cttgatatcc aagtcatagt cgatatattt caaggcctca tcgtccagca aaaaaggtga
    43141 agctagatta caataatagg aaaccccctt ttctctgatc attgctatta cattgaacca
    43201 gtatttttta tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga
    43261 ttcagtgact aatgtgtgat cattcacgcc gatcatagag tgttcgcttg tttttaatac
    43321 catggtatct cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac
    43381 aaactctcct tcttttggaa ctcccatagc aacccttcct taagcagcat tttgtgcttt
    43441 gtgtttgggt gttcattaca ccgacatcat aattattata tcaataaaaa tgagctttgc
    43501 ctagaaagga ttcctattgt ttcgattttt ctctaactga tctaccagtt tcatttggac
    43561 cttaggaaaa acgaccgaat caaatgcatc aggcttcaac cacttcgaag ttttgttctc
    43621 ggtaaattct tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa catgccattt
    43681 cagatgacta aaaatatgag taacttctcc taaatgtcgt gtctgccaaa caaagagttc
    43741 ctgcttttca aatgggagat tttgctcttc ttctgctact aggtcatcaa acagatcgat
    43801 ttctggcttt gtttcccatt cttttttcaa tcgctcatac tcctcttgtg tcacttccat
    43861 cattggaaat gtccacatat tcgccagcaa tttttggcta tctctttctt caaaataata
    43921 cgctccagaa tgattttgaa gagccgcact gatataataa acgtcttttg gctttgcttt
    43981 ttttgttttt acaggaaaac tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg
    44041 gatcggacaa gtctcacact ttggagaagt tggtgtacag atagctgaac ctagatccat
    44101 cattgcttgg ttgaattcac ctggatgctt ttcatcaatg attttccgca tcgcttcatc
    44161 aaagattttc ctgctagaag cttttgcgat gtctgcttca atgcaaaaca atctgctgac
    44221 tactcgcatc acgttgccgt caaccgcggg ttctggaagt ccaaatgcga tacttgcaat
    44281 cgcgcctgtc gtatatggtc ctattccctt caatgagcta atttcttcag gcgtttgcgg
    44341 catttcccca tcaaattctg acatgatctg tttagcagca gcttggatgt tccgggctct
    44401 tgagtaataa ccaaggccct cccatgcttt taaaagcttt tcttctggag catttgctag
    44461 ctcttcaatt gtaggaaacc attccatgaa acgataaaaa taatcgatca ctgtgtctac
    44521 tctggtttgc tgaagcatga tctcagagat ccagatacga taaggatcac gattatagcg
    44581 ccaaggcagg tttctttttt cttgttcata ccattgaatg aactgatctt gaaattcttt
    44641 tgtttcttta tctgtccatt tttcccattc tttattcact ttcctcttcc ttttccgtaa
    44701 tgaatcgctg gatcatatcc aaatcaaatc ctttttgata taagctttgc tttactttta
    44761 gatttctttt tttaggttca aaccttaaat ttcttcgcca tagtttatct ccttgtttga
    44821 ctaaataatc atattctatt tcttgatctg cttcttgcgg aagatcagcc atcgcttgtt
    44881 ggatcacttc ttgagaaaaa cctttcgtca tcaatgtttg ttggattttt ctcaataatt
    44941 ctttttggct ttttccgcga ttttttccaa acgctttttc ggctgtctga tgtgcatttt
    45001 gaacttggtc ttcaaatgta tattggctga gcgcttgttc aatgatttca ggtttcaaac
    45061 ctttttgctg catctgctgc gctaatttct ttggtccttt gtcacttaag cgcatattcg
    45121 tgcgcacata actttcccca tagaccaaat catcgacaag gtccaattct tttaagcggg
    45181 ctacgatttt atttcgatct tcttgaagga tttccttttc ttttaagtat gttcggattt
    45241 ctttttccga tcgcaactga taacttaagt aattcattgc taggtgaaaa ccgaaatcag
    45301 ctccgctact cttcttgatc tcttggatag tttcttcgtc taattcccgt ccttttaata
    45361 atcgatagcg tactaataca tcttcagata cttgtaaagc ttctccttca gataaatcta
    45421 cgcgatagaa agggcctttg cctttactga ttctcgtaac ggttaacata aacatcctcc
    45481 tcgaacatat attctctatc ataccacaga aaatccccgt aatcaggtat tatatgttag
    45541 aataaaccac agaaaaaaga aaaagggaga tacttatggc agaaacaatt gtcaaaactg
    45601 gacaaacggt tcctttgaaa atcaagcgtt taggcataaa tggtgaagga atcggttatt
    45661 tcaaacggtt gatcatattt gttccatatg cactaccaaa agaagaagta ctagtgaaaa
    45721 tcacgaaagc aactcctcgc tatgcagaag gagaattaat aaaagtcaaa aaaacaagca
    45781 aagatcgcgt agtggcacca tgtcctgttt actatgaatg cggtggctgt caattacaac
    45841 acttagctta tcaagctcaa ttggatttta aaaaggatct gcttttgcaa gcattggaaa
    45901 aattcaaacc agcaggcttt cgatcttatc aacttttgcc gacgatcggg atggatgagc
    45961 cttggcatta tagaaacaaa gcacaatttc agttacgaaa aaataagcag actcaaaaaa
    46021 ttgaagctgg tttatacgaa gcaaactctc atcagttagt ccctataaca gactgcttgg
    46081 ttcaagaacc tcgaacacaa aaagtaatga atactgttgt tcaactattg aataaatttg
    46141 atgcacccat ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc atggttagaa
    46201 tcggtgttaa aactggggag ttacaagttg tttttattac tcgcagtaaa aaattcccgc
    46261 aaaaaaacgc aatgatctgt gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc
    46321 aaaatgtcca ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc cacttatggg
    46381 gaaaagaagc cattgaagaa caaatcaatg aagtgacttt cgatctttct cctcgtgcct
    46441 tctttcaact caatcctcag cagaccgaat tgctttatgg cgaaggaatc aaagcattag
    46501 atgtccagcc taatgaaacg atcgtggatg cttattgcgg agttgggacg atcggcttaa
    46561 gtgtagcaaa acaagccaaa gaagtacggg gaatggatac cgttcctcaa gcaatcgctg
    46621 atgcaaaaaa aaatgcggaa agattaggat atcacaacac tcgatatgaa gtcgggacag
    46681 cagagcaagt tctgcctaaa tggttgaatg aaggttttca gcctgatggt atcatcgtag
    46741 atccaccacg tacgggtttg gataacgcat tgatccaatc attattgaaa taccctccaa
    46801 aaaaacttgt ttatatctcc tgtaatgttt ctacacttgc cagagatctg gttaatttaa
    46861 gtaaaaagtt caagattgaa tatttacagt ctgtcgacat gtttcctcag actgcacgtt
    46921 gtgaagttgt cgtgaagatg acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt
    46981 ctgccctgta tcaagtaata agaacagcca aacaaaaata gctcttcatg ttttatgaat
    47041 accgtacttg tgaccgaaga gttaacagga ggacactatt tatttaaaaa aagggttgtg
    47101 acatagtttt tgtcacagcc ctttttgatt attattggat attcacgtct atcacttgat
    47161 aaaatgcatt tgtcgtatcg ctgatattcc atactgctaa aatcacatta tatccttttc
    47221 gatcctgcgg aagtgtgatc gtttggttga ctgtttttgg tggaacagtt gctttgtcgt
    47281 ctatttttgt gatcaattca aaatcactaa atttcaaagg ttgattagga ttccaagttg
    47341 gtttggtaat gtagtaatcc caagtacttg tccgatgttg tgctgttaaa ttccaagtaa
    47401 tatttaatgt tcctggatta accatgtttt tatgccatct gttagatgtc tgttcatcta
    47461 aaggctcaaa gccgctgact cctgcactag caatttttcc atcaatgaat gtatttttgg
    47521 tagcttcgat actttgcggt tcccattgtg ctcttccgac attttgattt aagtttcctg
    47581 ctgctgatgt tcctaggtat gcacggcttc ctggagaagt aatataacca tgcgcaaaac
    47641 ctggaatgct aaaaccgaac aaccctaaac taactaaccc aataaacaat aacgtactaa
    47701 tctttttcat gtagaaacct ccttcatttg ataaccacat tgtaaacgct ttattgtatt
    47761 aacacaaaca ttatgctttt ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga
    47821 tgcagattat aacagaagta gacgagaaaa gtacaaatag aaaacatgag aaccaaatca
    47881 tatgatcttt ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt aataacaaca
    47941 atcatcaatt tttttcttac ttcacaaact aaatacaggt cttgctgtga gccttcatgg
    48001 taaactacta ttatagaaag gagttagtaa aatgaagatg ataaaagata ttcgtttttg
    48061 ggtttgtgtt ataggaattg tcatattagg ctttttatca gggttgctta gcggaaatcc
    48121 cggagaatat tactattctt tgcaacttcc accatttgca ccacctagct ggatatttgg
    48181 gccgatgtgg accttactgt atatattgat gggtatttct ctttatttgt tacttaatca
    48241 caacaacaaa aaacagcgaa acaatcttgt cggtcttttt gtgattcagt tcatttttaa
    48301 ttttatatgg tctgctctat tttttaattt aagaaatatt ttcattgcag caatcgatat
    48361 tacactttta gttattttct tgtcagtgct tatgtatcag ttgtggctac atcatcgcct
    48421 ggcaatgtgg ctcatgattc cttattattt atgggtacta ttcgcaactc tattgaatta
    48481 ttcaatttat tttttaaact aagcgctaaa aagagacgtc ctgtaattta acacatagaa
    48541 aaagtgccac ctaagttaga ttttttgtct aatttaggtg gcactcttta ttaaccaaac
    48601 tatttttttc tagtacccac ttgttgttcc atactcatta ttctggtcat aaccataacc
    48661 attttgttcc tgtccagcgt aaggatcata actttgagta tcttgacttg gtgtatagta
    48721 ctgacttgta tcttctgttt gctgataata ggtattcgga tcttggtact gatcatatgt
    48781 gttttctgaa taggaagaat aatcggtgta cccttcacta ttcgatccat caccgtttgt
    48841 cgaatcgcca tcttccgaat catcaaagaa catcattgaa gcattctcat ttttcaaatt
    48901 aggtaatgta tcgcttgttt ttatatttaa ttgtttcttc agttcatttt ggatcgaaag
    48961 aagatcattt tttcctaaaa tttgatagta gatatcattg atcatttgtc cttcgccttg
    49021 caactggtct tgtttgattg tttcaaacgc aggggtgtag ttcgtcgcta catcaagcat
    49081 gtcatcccaa tctaagtccg tcgtcacatt gttctcaact gcttttaaaa tttttctata
    49141 attgcttacg ccatctaaac ttaaaacttt attgacgatt ttcgtcacta cttcccgctg
    49201 acgacgttgt cgaccgatat cgccttctgg atcttcgtgt cgcattcgag aataggctaa
    49261 acctttttct ccattcaatg tttgttcacc tactggtaca tggacaccat ccaaagtaaa
    49321 gtcaatttta ttattcactt tgatgccacc gaccgcattg atcaaatctt ccatgccatc
    49381 caaattgatc gttacataat gatcaatagg aatatcgagc agttgctcaa ttgaatccat
    49441 ggccatttcg acaccaccaa atgcataggc atgatttaat ttatctaccg ttccataacc
    49501 tacgatattc gtataaatat ctcggtccaa actgatgatc gttgattttt tttgtttcgg
    49561 attaactgtt actaccatca tcgtatcaga acgtccttgt tccgttcttc ctaatccacc
    49621 ggtatctaaa cctaatagca aaaccgaaaa aggttctttg tcatcaatgc ttactctctc
    49681 agaacgtttg gaggatattc gattagagtt tttagaaatt ttgtttactg tttggctcgc
    49741 ttctcccata aatctgattc cgtatgctga taatccggca atcagcaaaa caaatacccc
    49801 taacaaggtt aatagaactt tttgccatcg cttcataata cacctctgtt tcacattttc
    49861 taaaatattg tctcatataa ctgttcaatc agcaaattca ctttttaatc ataagaaaac
    49921 tttaaaaaac atttttgtgt aacgattact attttttaaa atttctcaaa attcttaact
    49981 atcataccat accgtgaaaa agatcgaaag accgaataca cgcagttcgc aatcgtttta
    50041 tcttttttta cgtatttttt ccagaaaaag cgaacaacaa ggtattttcc aaataatcgt
    50101 gcagtaaaat gatcgcacat acctttccca tctttttaac agtctttgcc taccgttcag
    50161 attatcattc gatttcacga aaatttcttc ctatgactgg tccttttgtt aaacccatct
    50221 tctattcgtt ttatttccag ctcactgcat ggctcttaaa atgactcgaa ctagtgattt
    50281 cattaccatc atcttttaat ggatagatat gctcctcttc aaagtaaaac gattttcttt
    50341 taaagtaata gaattgacat ggtaatgagt atgtatacta gtggtttcac aaatggtctt
    50401 ttattcaaca tccaaaaact gaaatttctt taaaatccat tactaacgaa gaaaatgttc
    50461 cttgcttgat aattagttag gacatgtcaa gtgaacaaat gcatttactt agccaaaaaa
    50521 tctaaaaact tcataaatag acaaaaagac acgactctct aagaagtcgt gtctttattc
    50581 aacaaattat tataatttag tcacttcagc agcttgaggt ccgcgtgcac cttcaacaat
    50641 cgtgaattct acttcttgac cttcttctag gctcttgaag ccgtctcctt gaattgctga
    50701 gaaatgaaca aatacgtcat ctccgccgtc tactgtaata aacccaaatc ctttttcatt
    50761 gttgaaccat ttaaccgttc cgtgttccat aaatgtatag cctccaaaaa agttcttgca
    50821 agtaaccttg caagaacatt atacccaatt tagaaaacgc tagcaagctt tcgctctttt
    50881 attttccaaa ttatttttaa gactgatatg acggaggaaa tggttatttt gctgcttcga
    50941 aacgtttgtt tacttcatcc caattaataa cattccagaa tgctgcaata taatctggtc
    51001 ggacattttt atatttcaaa taataagcat gttcccaaac gtccaaacct agaattggtg
    51061 tctttccttc catcaatgga gaatcttgat ttgcagtaga ggtaatagct aattttccat
    51121 tttccattac aagccaagcc catccagaac caaatcgtcc agcggctgct tttttgaatt
    51181 cttctttaaa agaagaaaaa tcaccaaaag cttcattaat cgcttctttt atttctcctg
    51241 taggttcgcc accagcattt ggtgccatga tttcccagaa aaatgaatgg ttagcatgtc
    51301 cgccaccatt gttacgtaca gctgtcttga tatctgttgg aatagcgtcc atatcagata
    51361 ataattcttc tattgttttt tcgcctaatt ctgggtattt ctcaattgct gcatttaaat
    51421 tcgtcacata agtattgtga tgcttatcat gatgcagatg catcgtttct tcgtcaatat
    51481 aaggttccaa tgcgtcatat gcataaggta gatctggtaa tgtgtaagtc ataaaaaaat
    51541 tcctcctcaa tgttttcttt ataatgtcta cattacaaag agtaacaaag agaaggaaat
    51601 tcttcaattg ttatgcctag tcgtcttttt cactttgacc tacttcttct tcaaaaacct
    51661 cagtttcttt aaaaataaac aacttgctga aaatatagtt cgctaggata acaataattt
    51721 gagtgatgat tttcgccaca tactcattgc tgttcataac attgatcaac aataccattg
    51781 cccccatgtc caatccgtaa gaaaggatac ggtagaagaa gaacttaccg cattcaataa
    51841 gtgcatgtgt aaaattcggt gattttgaat ggaataccca aagtttgttc gttacaaaag
    51901 caaacaatac agaacaaaac cacgaaatag aattggataa ggccatactt aaatcaaaat
    51961 attggcgtgc gagagcaaaa ctaacaaaat ttacaatcgt agccaaacca ccaaaaaaga
    52021 gatagactag tatctcccaa tatccttttg cttctaaata tccttttaac tgtcgatact
    52081 gcttcatgag ccaacctacc ttattaaaaa ttcttattta tcatactcta tatttcaata
    52141 actttcatct ttatttaaaa aaattaattt tttttgatcc tttgcctttg tctctgcttg
    52201 gatcgtcaca tgtgtaatac catattttaa ttttaataaa gaaattatac gaggatatat
    52261 cttttcaatc tcgcttagta gctgatcttc aaaatcaata tgtccgtcga aaataattat
    52321 cttttcgcta tactgccaaa tatggacatg atgaacattc tttaccccat cgattgcttc
    52381 aatttcttgt tccatttttt catagtcaat agcaggtgca ctttgtatca aaatagcggc
    52441 agcttttttg atcaccatta tcgcttctat caatatatat atcgaaatga tcagtgtaat
    52501 aactggatcg atccagtaga tatcgaaaaa acggatcaaa attgctccga taatcacact
    52561 taccgaagac agtgtatcac ttaacaaatg caaataacta gattttatat tcaaactttc
    52621 atctgcttct tgtcgtaata ataatactga gaacaaattc gctagcaatc caataactgc
    52681 tactgttagc atcaaatgac tatttatctt ttctggtgaa gtgaaccgct tgaatgcttc
    52741 aacggttaaa aacaaggata atatgatcaa tatgaatgag ttgatgaaag cactcaatat
    52801 ttctaaacgc tggtagccat acgtacgttt tttatttgct tcttttcggg ccattttttg
    52861 tgccccgtaa gaaaaaataa ttgccaatgt atcactaagg ttatggaaag catctgaaac
    52921 aagagacaaa ctccctgaca taatccctcc aataaattct gataaagtga tcaccgcatt
    52981 caaaaccact actccaaata gtttttttga tgatctctgt ggctgtgtag gcactattcc
    53041 ttcctccatt ttatttatat tggatagtct ttagacaaga ataacatttt tttgatattt
    53101 caccaatcat tcagatgttt ccctaaagca cttgtatttc acttgatact tcgctagaat
    53161 tgcaagtgat gacactacta gatgaggagt acttatgaca acaaaacaat taattatcag
    53221 ttcctttata cgattcaaag acctaaagga ggcgagaaat gtcccatttt ggaaagccat
    53281 tgtctatctt ttagttttga gtataattat ggctttgcca atctcttttc aagtttttca
    53341 agtcttaaat aacattcaat tggatgggca aaagattgct actcgcattc ctgattttac
    53401 aatccaaaac gggcagcttc aaaccgaaga aaaagaagga ttcatttacc aaacaaactc
    53461 cattatcttc acatttgatc cagagggaaa acgaacagaa caggacatct ctactgattt
    53521 gatggggaat tttgttagtg tcgggatgtt aaaaaacaaa cttatcatag ctcttcctaa
    53581 tacaggcacg acttctgctt tgttgaacaa taaccaatta gaacttccct acaccaatga
    53641 atctttaaaa aacttaacag gtaagcagct ccgttctttt ttaagtgaag catctatacc
    53701 actttggata aaagtcctga catttatatt ttctatttat cctagttttc tgaatctgct
    53761 gatcactttg ctatttacca acattgctgc ttttctctat gcacgctttc gactaacaaa
    53821 agctactttt cttgattgtt taaaaacatt gatctattca atttcattgc ctactataat
    53881 tgcaacaatc ttgatggtct ttcttccttc ttttgacact agcgccttca ttgcttttgc
    53941 aggaatcttt atttttgctc aagctgtcaa aggatgggca aaaatatcga tcaattaaga
    54001 aataaagaca actcgttatt tctacttaaa tagacccttt tagaggttgt gacatttttt
    54061 tgtcacagcc ccttttttat ttgaaaaata tttctttctc aaaaaacaag caaggcgctt
    54121 caaagttctt cttgtatgcg ctacacttag agtaaagaaa ggcgggaaat taactatgtc
    54181 agaaagaatc atttatgcag atcgtccatt tcgtgatgaa tttatcgaag aaatccatac
    54241 tatagcgcct ggttatatct ttaaaacaga attacaacca gaggatctac aaaatgtaga
    54301 gatcagtttg ggctggaact cagactacca agaaaaacta ttagcctctt ctaccttgaa
    54361 atgggtccaa tctatctcag ctggtgttga tcagctaccc cttgagactt tttcaaagaa
    54421 acatatttta ctttcaaatg gtagtggcat ccacagtgaa tcgattacgg agcatgtctt
    54481 aggaatcatc cttgggtatt ctcgtggtct ttttcaagca caaaaggcac agagtgacat
    54541 gaaatggtta ggttcatcgg tccattacca atctatccaa gggaaaaaaa tactaatcat
    54601 tggaactggc catattggaa aaatgattgc aaaaaaatgc aaagcattag acatgaactg
    54661 ctatggaatc aatacatccg gtcatccagc agaaggaatg gaaaagactt tttctttaaa
    54721 tcaactaaag gaagttcttc ctgaagtaga tttcgtagtc aatatcttac ctctaacgga
    54781 ggaaacaact gggctctttg atcagcatat gtttgaacac tttgatccaa aatctgtatt
    54841 catcaatgtt ggccgtggtg cttctgttaa gacacaagat ctggtgcagg ctttaaataa
    54901 ccagcaactt tcctttgcag cattagacgt ttttgaggaa gagcctcttc cacaagatca
    54961 tcctctttgg aaaatggaca atgtactgat tacttcccac attgcaggtt tgacacctga
    55021 ttttcaaaag aaattaatgg ctattttttt aaccaatctg aaaagctact ttgccaccca
    55081 tgagcttcaa accaatcaag taaaattgtc tgcaggatat taatagctga aaacaatatt
    55141 ttcaaaagaa aaaagagaag gtgacaaaaa ttgtgtcacc ctctcttttt ttattgtttt
    55201 ttaaagtgat aggttggctc ctccaggttg ggatcataat caacaagtaa atcatatcct
    55261 ttaaagaacc attcatctgc ttcctcgata aaaaaaagtg tcccatccat ttccactttc
    55321 tttacaggat gttctggctg ttcaactgac attccaatcg aaaaaccatc atgaacctct
    55381 gttttgccgt agacttttcc aaaaaaacgt attccgtaag tttctggcag atcaatttct
    55441 gagtcaaacc atttttgtgc ttttggcgtt accgttaatt tcatcccaac aacctacttt
    55501 ctcttttctt tctattgatt catcttatcg tctagaatat ccacatcgcc tgtctctcca
    55561 ataaccagta gattatcatt ttcacgaaca tattcatctg ctgcaggaga agcgataacc
    55621 gtttgatcta ctcttcgtat ggcgactact gttaagtcaa aacgttgcct gaaatttaat
    55681 tcagctaatg ttttgttgaa aaatttagga ttggagactc ggatttctgc taaagaatat
    55741 ttatctgaca gctctaagta gtctagaata ttctttgata ctaagttatg tgcaatccgt
    55801 atccccatgt ctcgctcagg gtgtacgaca cgatctgctc cgatcttctc tagtacacgg
    55861 gcatggtact cattttgggc ttttgctaaa atattcggta cgcccatttc ctttaccatc
    55921 agagtaacta agatgctggc ttggatatct tctccaatag cgacaattac atgatcgaaa
    55981 tttcttatac ctaatgaacg aagtgtcatc tcatcctgtg catttgccac aacagcatgg
    56041 gtggctatat tcatatattc attgactcga tcttcattac tgtcaatagc cagtacttct
    56101 tgtccagctt cgatcagtgt acggcagatg cttccgccaa atcgtccaag gcctacaatt
    56161 gcaaaatttt gtttcaccat tttcctcctt tagtatcttc ttttctcagt ataacaaagc
    56221 ctttccaaaa acaaaagcaa gcatcattat tgtaaaaaag ccaagaaaaa taatagttat
    56281 tttctcagct tttgattatc ctctttatca tcgtttttat ttcaccaaac catgtttaaa
    56341 cgcatagata gctgcttgag ttcggtcttc tacctctaac ttagctaata tattcgacac
    56401 atgcgttttg actgttttca gtgtgataaa caattcatcc gcgatttcct gattactttt
    56461 cccttcagaa atcagcatca aaatttcatt ttctcgattc gttaattctt catgcaatac
    56521 tggatcattt cgccgactca ttttttccat catttttgtt gtcacttcag gttctagtac
    56581 tcgctcgccg cgttgcgtag cccttatagc atcagctatt tcatgtgctg tagacgtctt
    56641 caacaaatat cctgctgctc ctgcttcaat tgcaggataa actttttcat catcaataaa
    56701 acttgtgacg ataatgattt tggcttttgg ccaatctttt aagattgctt ttgttgattc
    56761 gatgccatcc atttcttcca tgactagatc cattaaaatg acatccggtc gaagtgccat
    56821 cgccttttca tagccttgac gtccattttc agcttctcca atcacttcaa tgtcttcttg
    56881 gatagataaa taagaagaga cgcctaagcg taccatttca tggtcatcta ctaataaaac
    56941 ttttatcatc tttatctatg cctccttcat caaagggacc ttggtctcca cgctcgtacc
    57001 ttgcccttta aaactaatga tttttactgt tccaccaata ccagctactc gttctttgat
    57061 attgttcaat ccataacttc ccgttttggt ttcattcata ttaaatcctg tcccgtcgtc
    57121 aatgatacgt aataaaagat tgttatctat tttatgcaaa tagacttcta attcattagc
    57181 cttagcatgt cttaatgtgt ttgataacaa ttcttgaacg attcggaaca agtgatcctc
    57241 aatggaacta gttaatttta catcttctac ctcccatttt agcgaaatct ggattttatt
    57301 ctgcaattcc ttcaataact gctcaatgcc ttgttttaaa cttttttctt ctaaattgac
    57361 tggacgcaga tgaagaagca gcgcacgcat ctcagactgg gaagcgttga tgatctctgc
    57421 caccattttc aactgcttac ggaacatttc tggtgtctca cttttttctg cttgctccgt
    57481 caatgccgac atcatcatca tcgctgcaaa taattgctgt gaaactgaat catgaagctc
    57541 acgagctaat cgatgccttt ctaattttaa aatctcttct ttggtttgtc catctacata
    57601 ttgaggacgg ctagtcataa tctgtaattc actggatact tcgatcattt tttcttttat
    57661 tttagtaatt tccatatcaa tatctttgat gtacagatca tccgacgcgc ttgggatcgg
    57721 ctgatgcaaa agtttggatt cataattgcc agaagaaagt gcacgaagct tttcttcgat
    57781 tttcccgtat tttgcctttt gaataagtga taacaataga aatacgatca atcctacacc
    57841 taatgaaatt gccatcaaat ggaagataag cggaacgtat aataaacgcg cacgcagcaa
    57901 ttctccccac caatgacttt ggttactggc ataaaaataa gtgaaaagtg aaaatagaat
    57961 aataaggaaa gccgcaatcc ccgaataaac agctagcatt gctttggata ttcttcccat
    58021 catattcgta tcacctcgac atctccaacc aaagtattgg taatgatctt caatctgcga
    58081 ggattttcat cataatcact gctgcagatt ttgatctgtt cgttttttaa ggaaaactgc
    58141 tcttcttcaa acaagacatt tcctactaat gtcgcatgct ctaaacgaat agccactccc
    58201 aggggtacta agatccgtgt tctgcctatc ccttttctta caatcacaat attatcatct
    58261 tttggcaaaa gtgtattgcc caaatcgatg atagtatcac cagaaatgat ggcaatgttg
    58321 atatcatccc attcatagac gtcgtttcca atacgttggt taccaaataa ttgctgtctt
    58381 ttacgctcat tattatgtgt ttttaattgc tctgtttgga ccatcatgat ctgttttttt
    58441 cgccaaaaag cattttttgt caaatctatt cctgaaatct ctacaccttt cagcccgata
    58501 aataaaacgg ccaatacaac catcatccat aaagcaggac tgttgactaa gctaaaaaaa
    58561 atgaccaagc tccctaagat caattgaaaa ttttgaaatt tagtacgagg atatttgcgc
    58621 atagctagat atatattgaa aataccgaat attactaaaa gcaaaagtcc agtattgttt
    58681 acgatttgcc aaacagcaaa taacagcagc agtgcttcga ctaccacaaa aaaacgccaa
    58741 gaactattca tcgctttttc tccctcctga cacattctca tttcatcata cctatttttt
    58801 tgactgttgg ctataggact ttagatgtaa gatcgttcag tgaaacctgc aatactcaaa
    58861 gagaaaagat ctagagtgcg tcatcagtaa gatgaactct ctagatcttt cagtcagact
    58921 acgcttgttc tactttgacg attttaacta acatatcgcc acctggtgta gcaatggtta
    58981 cttcatcatt tttacgtttg ccaatcaatg cttgcgcgat aggagaatca ttggaaatct
    59041 ttccagaaaa cgggtctgct tcagcacttc cgacaatcgt gtactcttct tcatctccat
    59101 caggcaactc gatgaacgta actgttttac cgatcgatac ctcatctgca tctacgccgt
    59161 cattatcgat gatttgtgca aaacggatca tattttcaat tgttgtgatt cttccttcaa
    59221 caaatgcttg ttcatcttta gctgattcgt attcggagtt ttcggaaaga tctccgaaac
    59281 cgcgagcgat tttgattcgt tcaatgattt ctccgcgttt aactgttttt agttcttcta
    59341 attctttttc taatttttct ttaccttcta gagtcattgg ataaactttc tctaccatgt
    59401 gtaacgtctc cttttttcga taaaataccg caaaaggtaa tcttttgagg aatatagtcc
    59461 aaaaaagatt accacgcttt tcttaaaatg taaatgtttt tctaaaaatg atcaatgact
    59521 agcccctgtt tttctaagaa ttatttacat atttttgcac tagttccata tgttcttcat
    59581 acgttttagc gaaataaaca tttccagtgc tcgtatctgc tacgaaataa taatagtcat
    59641 tttctgctgg ttctaatact gccttgattg cctcttcgct tggattgtca aaaggaccag
    59701 gcccatagcc ggtattggta tacaaattgt atggtgaatc tacagctgta tcttcatacg
    59761 tcaccaattc tttatgttct cctaatgcat ataaaacaga gatatctgac tgaagtggca
    59821 tatttgcctt gattcggtta aagaagactt gtgcaatatt tttacgatca ttttctttta
    59881 cgccttcttt ttcaactaga gaagccaaag ttaaaacttc ttgtacagtc aaatttttct
    59941 gtttgatagc tgaataatag ttttgcatga ccgtatttgt tttgttcacc atctcaatca
    60001 caagatcctt aagcgaagta ctcgtgtagt aatcataagt agctgggaat aagtagcctt
    60061 ccaaacggta ttttgtgttc tcagctttag aggcactttc caacaattct gggaattttt
    60121 gatacaactc gttaaagaaa gtctcatcat ttactaaatc taaaaattct ttcttgtctt
    60181 taccagttac cttcgctacc cgctcagcaa tctgatcgat gtcgtagcct tctggaatgg
    60241 caattttccc atctgcaact tttgttggct cagaagtgcc gccttcttgc agctgtttgc
    60301 caatctcgtc aagagtcata ttaggcgcta actgataata gccagcttga aagccagtta
    60361 aatttttaaa ttttgtataa taattgaaaa caatcccgct tttaataata ttgtccttct
    60421 ccaaaatctc accaatctgc ttgttagaag agccactcgg gatctccact tggactaatt
    60481 ggtcatctga tttatctaaa ggcttcaacc cgctatctac ataacgatac acggtaaatc
    60541 caagaaatcc gccaataatt aataatgtaa gagcaatcac taaaatgatc ttcctcacaa
    60601 tcttatcttc ttttttacgc agatttctcc gcttgtcgat tatatctgct gtagctgcct
    60661 tactggcttc ttttttatct ttacttgggt gttgtttgtt tcctgacaaa acaactcctc
    60721 cttactatca tcttcgtaac tctgtttatt atacatgaaa tttctactgc cgtgaattat
    60781 tttaccaaat attatgtcaa aattgtaagt ggcaaatact ctttttgagg attacaatga
    60841 aaaatagtta aaaatggata gaaaggaatt aacatgtcaa aaggaaaaca tcgaaaaaaa
    60901 caaaaaattt ctatttcttt tcttgtaatt ttattattgt ctgtcagctt cttttcaaca
    60961 ggcatcatta taggaggtca attaacaaaa atacctcatt cccaaactta taaagcggag
    61021 ccaacacaac ttacttccaa tttaacgccc gatgagcaga ggcttgctag caaaattgat
    61081 caattactac aaaaatcaga ttatatcggt tcgatttatg ttcgcaaaaa taatcgcgta
    61141 ctattagaaa aaggatatgg atatgcaaat ctgcgcgtaa aagaatcgaa ttcaccttct
    61201 atttactatc aaatcggttc gattcaaaaa gcaatgactg ctttactgat actaaaacaa
    61261 atccaagctg gtaagttaac ttttgacaca aagttagcag aattttatcc tcagattcct
    61321 ggaagtcagc aaatcacaat caaaaatatg ctttatatgc gctctggtct tcatcgaact
    61381 gcttctcccg acaaacctat gtcggatagt gaaatcattc agttcgccct tcatcatttg
    61441 aaacttactg attatgatac gtatcattat gaaccattga attatacatt gcttacaggg
    61501 atattgatca aactaacgaa tcagccttat gaaactcttc taaaaaaaga aatcattcgt
    61561 ccactccatc tagaacatac agatttttat gacaatgtaa aaaattcgcc tcaacatgct
    61621 gtatcttacc agatgtctgc aactgacgat tattcaaaag cattgatcga gcctgaaacc
    61681 gacatccgaa atgaattagg tacaggaaac ataagtatgt ctgtttatga cttgaacaaa
    61741 ttctttacca gtgttctttc tggcggtatc ataccaaaag aactactttt ctcattgtgg
    61801 caaaataatg gtgataaaca tccttacagc ggcggtgttt acagtggaaa cgattatatc
    61861 cttgctcagg ggaatatcaa tcgattccat gcagtagtgg cgatgaaaaa agacactaaa
    61921 gatgcaatcg tcatggaaag taatatccaa tcggataaga acatcaaatt gccggccact
    61981 gatttaagaa atcagattta tgaactgatg gaaggtgttc acttatcaaa ttaaattttg
    62041 acataatatt agttgtcatc tctgtatagt caatttagtt agtactctat ctgaaaagta
    62101 gaaataaatt aacaaatatt atctgtcctt attatttgtt aatttatttc ttatttta
//
LOCUS       DAIGTA010000009        61729 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.009, whole genome shotgun sequence.
ACCESSION   DAIGTA010000009 DAIGTA010000000
VERSION     DAIGTA010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.009"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(59..187)
                     /locus_tag="NOB43_000586"
     CDS             complement(59..187)
                     /locus_tag="NOB43_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI0981479.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="NOB43_000587"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="NOB43_000587"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI0981480.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="NOB43_000588"
     CDS             complement(1674..2729)
                     /locus_tag="NOB43_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI0981481.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="NOB43_000589"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="NOB43_000589"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HCI0981482.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="NOB43_000590"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="NOB43_000590"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HCI0981483.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="NOB43_000591"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="NOB43_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HCI0981484.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="NOB43_000592"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="NOB43_000592"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCI0981485.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="NOB43_000593"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="NOB43_000593"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HCI0981486.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="NOB43_000594"
     CDS             10491..12050
                     /locus_tag="NOB43_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HCI0981487.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="NOB43_000595"
     CDS             complement(12161..14092)
                     /locus_tag="NOB43_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0981488.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="NOB43_000596"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="NOB43_000596"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCI0981489.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="NOB43_000597"
     CDS             complement(15021..15773)
                     /locus_tag="NOB43_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0981490.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="NOB43_000598"
     CDS             complement(15932..16141)
                     /locus_tag="NOB43_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981491.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="NOB43_000599"
     CDS             complement(16152..17480)
                     /locus_tag="NOB43_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981492.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="NOB43_000600"
     CDS             17616..17771
                     /locus_tag="NOB43_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981493.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="NOB43_000601"
     CDS             complement(17845..18432)
                     /locus_tag="NOB43_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCI0981494.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="NOB43_000602"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="NOB43_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HCI0981495.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="NOB43_000603"
     CDS             complement(20012..21301)
                     /locus_tag="NOB43_000603"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCI0981496.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="NOB43_000604"
     CDS             complement(21455..22387)
                     /locus_tag="NOB43_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981497.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="NOB43_000605"
     CDS             complement(22544..23203)
                     /locus_tag="NOB43_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI0981498.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="NOB43_000606"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="NOB43_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCI0981499.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="NOB43_000607"
     CDS             complement(24244..24534)
                     /locus_tag="NOB43_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981500.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="NOB43_000608"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="NOB43_000608"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCI0981501.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="NOB43_000609"
     CDS             complement(26821..28176)
                     /locus_tag="NOB43_000609"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCI0981502.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="NOB43_000610"
     CDS             complement(28200..29369)
                     /locus_tag="NOB43_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981503.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="NOB43_000611"
     CDS             complement(29366..30253)
                     /locus_tag="NOB43_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HCI0981504.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="NOB43_000612"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="NOB43_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCI0981505.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMTIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="NOB43_000613"
     CDS             34320..34841
                     /locus_tag="NOB43_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI0981506.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="NOB43_000614"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="NOB43_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="NOB43_000615"
     CDS             complement(36284..36940)
                     /locus_tag="NOB43_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981507.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="NOB43_000616"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="NOB43_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HCI0981508.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="NOB43_000617"
     CDS             complement(38477..39475)
                     /locus_tag="NOB43_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HCI0981509.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="NOB43_000618"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="NOB43_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCI0981510.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="NOB43_000619"
     CDS             complement(40491..41222)
                     /locus_tag="NOB43_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HCI0981511.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="NOB43_000620"
     CDS             complement(41226..42491)
                     /locus_tag="NOB43_000620"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HCI0981512.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="NOB43_000621"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="NOB43_000621"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCI0981513.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="NOB43_000622"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="NOB43_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HCI0981514.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="NOB43_000623"
     CDS             47833..49335
                     /locus_tag="NOB43_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HCI0981515.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="NOB43_000624"
     CDS             49337..50074
                     /locus_tag="NOB43_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0981516.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="NOB43_000625"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="NOB43_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCI0981517.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="NOB43_000626"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="NOB43_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCI0981518.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="NOB43_000627"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="NOB43_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCI0981519.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="NOB43_000628"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="NOB43_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HCI0981520.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="NOB43_000629"
     CDS             complement(55574..56740)
                     /locus_tag="NOB43_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCI0981521.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="NOB43_000630"
     CDS             complement(56756..56983)
                     /locus_tag="NOB43_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCI0981522.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="NOB43_000631"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="NOB43_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58992)
                     /locus_tag="NOB43_000632"
                     /pseudo
     CDS             complement(57969..58992)
                     /locus_tag="NOB43_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(59476..59637)
                     /locus_tag="NOB43_000633"
     CDS             complement(59476..59637)
                     /locus_tag="NOB43_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981523.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="NOB43_000634"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="NOB43_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61417
                     /locus_tag="NOB43_000635"
     CDS             60827..61417
                     /locus_tag="NOB43_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HCI0981524.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT        17127 a        13256 c        10688 g        20658 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atatcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagtcat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacatgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt catagatgga atggcaacag tttttttgac
    61561 aaattttata aggtgcagaa cttctttccg tatgctattc cgattgtcct tgacaatgag
    61621 cctcctcgga tgtgacgatc ttcggcagga gctaacagtt aaagttagac tgcctcgcta
    61681 gcgttagcac atccgagctc attatcaagg attcgctgcg ccaatctct
//
LOCUS       DAIGTA010000010        61706 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.010, whole genome shotgun sequence.
ACCESSION   DAIGTA010000010 DAIGTA010000000
VERSION     DAIGTA010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.010"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            591..1280
                     /locus_tag="NOB43_000636"
     CDS             591..1280
                     /locus_tag="NOB43_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0981525.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="NOB43_000637"
     CDS             1267..2475
                     /locus_tag="NOB43_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0981526.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="NOB43_000638"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="NOB43_000638"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCI0981527.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="NOB43_000639"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="NOB43_000639"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCI0981528.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="NOB43_000640"
     CDS             complement(6578..7273)
                     /locus_tag="NOB43_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HCI0981529.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="NOB43_000641"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="NOB43_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCI0981530.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="NOB43_000642"
     CDS             complement(8472..8663)
                     /locus_tag="NOB43_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HCI0981531.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="NOB43_000643"
     CDS             complement(8684..9574)
                     /locus_tag="NOB43_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HCI0981532.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="NOB43_000644"
     CDS             complement(9561..10328)
                     /locus_tag="NOB43_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0981533.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="NOB43_000645"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="NOB43_000645"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCI0981534.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="NOB43_000646"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="NOB43_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCI0981535.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="NOB43_000647"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="NOB43_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCI0981536.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="NOB43_000648"
     CDS             14899..15282
                     /locus_tag="NOB43_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981537.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="NOB43_000649"
     CDS             complement(15450..16208)
                     /locus_tag="NOB43_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HCI0981538.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="NOB43_000650"
     CDS             complement(16226..17044)
                     /locus_tag="NOB43_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI0981539.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="NOB43_000651"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="NOB43_000651"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCI0981540.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="NOB43_000652"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="NOB43_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCI0981541.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="NOB43_000653"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="NOB43_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCI0981542.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="NOB43_000654"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="NOB43_000654"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCI0981543.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="NOB43_000655"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="NOB43_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HCI0981544.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="NOB43_000656"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="NOB43_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCI0981545.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="NOB43_000657"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="NOB43_000657"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCI0981546.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="NOB43_000658"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="NOB43_000658"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HCI0981547.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="NOB43_000659"
     CDS             27086..27385
                     /locus_tag="NOB43_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCI0981548.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="NOB43_000660"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="NOB43_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI0981549.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="NOB43_000661"
     CDS             27973..28209
                     /locus_tag="NOB43_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCI0981550.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="NOB43_000662"
     CDS             28352..30325
                     /locus_tag="NOB43_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HCI0981551.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="NOB43_000663"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="NOB43_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCI0981552.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="NOB43_000664"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="NOB43_000664"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCI0981553.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="NOB43_000665"
     CDS             33204..34496
                     /locus_tag="NOB43_000665"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCI0981554.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35232..36095
                     /locus_tag="NOB43_000666"
     CDS             35232..36095
                     /locus_tag="NOB43_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0981555.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36224..37846)
                     /locus_tag="NOB43_000667"
     CDS             complement(36224..37846)
                     /locus_tag="NOB43_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0981556.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38095..38616
                     /locus_tag="NOB43_000668"
     CDS             38095..38616
                     /locus_tag="NOB43_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI0981557.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38802..40531)
                     /gene="spxB"
                     /locus_tag="NOB43_000669"
                     /pseudo
     CDS             complement(38802..40531)
                     /gene="spxB"
                     /locus_tag="NOB43_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
     gene            40696..41514
                     /locus_tag="NOB43_000670"
     CDS             40696..41514
                     /locus_tag="NOB43_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HCI0981558.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41617..41814)
                     /locus_tag="NOB43_000671"
     CDS             complement(41617..41814)
                     /locus_tag="NOB43_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981559.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41983..42561
                     /locus_tag="NOB43_000672"
     CDS             41983..42561
                     /locus_tag="NOB43_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI0981560.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42656..42793
                     /locus_tag="NOB43_000673"
     CDS             42656..42793
                     /locus_tag="NOB43_000673"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981561.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43606..44109)
                     /locus_tag="NOB43_000674"
     CDS             complement(43606..44109)
                     /locus_tag="NOB43_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI0981562.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44468..45493
                     /locus_tag="NOB43_000675"
     CDS             44468..45493
                     /locus_tag="NOB43_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0981563.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45840..46718
                     /locus_tag="NOB43_000676"
     CDS             45840..46718
                     /locus_tag="NOB43_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HCI0981564.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47194..47310
                     /locus_tag="NOB43_000677"
     CDS             47194..47310
                     /locus_tag="NOB43_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCI0981565.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48238..48576
                     /locus_tag="NOB43_000678"
     CDS             48238..48576
                     /locus_tag="NOB43_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981566.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48670..48900
                     /locus_tag="NOB43_000679"
     CDS             48670..48900
                     /locus_tag="NOB43_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981567.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49300..49671
                     /locus_tag="NOB43_000680"
     CDS             49300..49671
                     /locus_tag="NOB43_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HCI0981568.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49945..50637)
                     /locus_tag="NOB43_000681"
     CDS             complement(49945..50637)
                     /locus_tag="NOB43_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0981569.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50640..51425)
                     /locus_tag="NOB43_000682"
     CDS             complement(50640..51425)
                     /locus_tag="NOB43_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0981570.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51662..53062
                     /gene="lacG"
                     /locus_tag="NOB43_000683"
     CDS             51662..53062
                     /gene="lacG"
                     /locus_tag="NOB43_000683"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI0981571.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53087..53404
                     /locus_tag="NOB43_000684"
     CDS             53087..53404
                     /locus_tag="NOB43_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0981572.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53417..55090
                     /locus_tag="NOB43_000685"
     CDS             53417..55090
                     /locus_tag="NOB43_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HCI0981573.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55104..56735
                     /locus_tag="NOB43_000686"
     CDS             55104..56735
                     /locus_tag="NOB43_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HCI0981574.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57596..58786
                     /locus_tag="NOB43_000687"
     CDS             57596..58786
                     /locus_tag="NOB43_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HCI0981575.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58920..61109
                     /locus_tag="NOB43_000688"
     CDS             58920..61109
                     /locus_tag="NOB43_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0981576.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61106..>61706
                     /locus_tag="NOB43_000689"
     CDS             61106..>61706
                     /locus_tag="NOB43_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI0981577.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNI"
BASE COUNT        19195 a        11235 c        12197 g        19079 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tatattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagac caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgttaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggattaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggcggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccgtc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagactat gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atgggaaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatct
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaattct tgaaaactat
    25441 atcgaacatc agcgcgaagt catcacaaga cggacagtct ttgaaaaaga aaaagcagaa
    25501 gcaagggcac acattttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaagcaaaag cgacgatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgcacagc caaaggaata ccaattatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggttagagg aatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aagatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaatag ccatcaagac taattgtgta agctagcaag
    26881 aatgaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataatcag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattggatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaac gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atatcgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaacact gtttattcag aataagggac tgtgacaaaa accgtgtcac
    34621 agtccctttt tccgaacaaa cggtgttcaa aagcttgcat ctacggcact aagcccaatc
    34681 agatgaaaaa tatggagtgc tatttttatc tgattgttct tactgcttga tgcagagcag
    34741 ctttttcaca acctctccac taaacggtgt tctcctgcca actcctcggt cacaagtcac
    34801 aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact cggagctaaa
    34861 cggcaggctc acaacctctt ggtaaacggt gttcaatcag ctgaccctcg gtattagctc
    34921 aaaaaacggc aaaatatgag gaactatttt ttccgttttt ttctctaata ctcaggtcaa
    34981 aacgctgatt tcacaacctc tgattcacgg tgttccagaa gtagcttcta cggaaataag
    35041 ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc
    35101 tgaccacttc tgtcacaacc tattattttg attagaactt gcgaaaataa accggttaaa
    35161 gtgtgtctag cgcaagagat ttgctataat agacgataag ggtaaaatgt aacgagaagg
    35221 ggttgaaaaa tgtgtatcaa attgtaacag attcttgttg tgatctgcca taccatgtat
    35281 tagcaaaaga aaaagttgat tttttatcaa tgaatctcca attgaatgat caagagttag
    35341 tagatgacct cggaaagaca ttcaattatg accgctacat gaatcagctg aaaaatggtg
    35401 cgatgcctac gacatcacaa atcaatgttg gccgatattt agaatttttc cgttcttatg
    35461 cggaaaaaca gattcctgtt ttatatgtgg ctttttccag tggattaagc ggctcttaca
    35521 gtagtgcgct tcaagcggtt gaattgctga aggaagaata tgaagaccct gagatctatg
    35581 tttttgatac aaaagctgca agtattgggg aagggctttt agtattggaa gctgtaagat
    35641 tgaaaaaaga aggtaaaagc atcgaagaaa ccctagagtg gctggaaagt aattatttga
    35701 aagtccattc atgggtaaca gtagacgatc tgaaatatct agaacgaggc ggtaggattt
    35761 ccaaagcaag tgctactctt ggcagtctat tgagtgtaaa gcctattatt acggtggata
    35821 aagaaggaag gctgacgaat gttgacaaag ttcgaggaag aaacaagtcg atccagacaa
    35881 tcgtcaatga gacggtaaaa acaatcgttg caccacttga tcaaatcgtt tatgtggctt
    35941 acgctgggga tctagagagc gcggagaagg caaaacggct tttggaagag cagataaaga
    36001 tgaaagatgt gaagctttat cccttaggac caacgatcgc cagtcacaca ggctatggct
    36061 gtatcgcgat tttttcgatg ggaatcagtc gataaaagca gtaactcatt ctgtaaaaaa
    36121 gcccagaaat tgattgtaac aaaaacagcg actcttaaaa gatagatgag catcctatct
    36181 cttagaggtc gctgtttttt tattttttaa gctaaatagg ccattatgcc cataactcgt
    36241 tcaattgttt ttgaatatct gcattttcca aaaattcatc atatgtcgta tcagctcgat
    36301 cgatcacacc tttatccgaa acggcaatga tgcggtttgc caatgtttgg ataaattgat
    36361 ggtcatgtga cgcaaataag attgagccag taaatgccat caagccgtca ttcaatgctg
    36421 tgattgattc taagtctaaa tggttcgttg gatcatctaa tacaagtacg ttagctttcg
    36481 aaagcatcat ttttgaaagc atgcaacgga ctttctctcc accagataaa acattcactg
    36541 gtttcaatac ttcttcacca gaaaacaaca ttcttcctaa gaagcttctt aagaaggtgt
    36601 tatcatcttc ttctttactt gcatattgac gcaaccagtc taaaatcgtt agatcagtat
    36661 cgaattcttt cgttgtatcc tttggtaaat aagaattact tgttgtcaca ccccaacgta
    36721 ctgttccagt atctggcgta atttcaccca tgataacttt gaatagcgtt gttgttgtta
    36781 tatcattttc tgcgacgaaa gcgaccttgt cttctttgct caaattaaaa gatatatcat
    36841 ctaaaatttt ctttccatca atcgttacac ttacattttc tacctgcaat aagtcgtttc
    36901 caatctcacg ttcaggtttg aatccaacga atggataacg tctagaagaa ggttggatat
    36961 cgtctaaagt aattttttca agcatttttt tacgtgaagt tgcttgtttt gattttgatg
    37021 cattcgcact aaagcgggca ataaattctt ggagttcttt gatttgttct tcttttttgg
    37081 catttgcgtt tgcttgaagt ttagccgcta gttgactaga ttccaaccaa aaatcataat
    37141 ttcctacata aagtttgatt ttaccaaaat ctagatccgc catatgtgta catactttgt
    37201 tcaaaaagtg acggtcatgg gatacaacga tcacagtatt ttcaaaattg atcaaaaatt
    37261 cttccagcca attgatcgat tggatatcca gaccgtttgt tggttcgtct agcaaaagaa
    37321 catcaggttt accaaatagt gtttgtgcta ataacacttt taccttttgt ccaccagtta
    37381 attcactcat ttgctgatgg tgcaattctt cagggatgtt cagaccttgc agtaaaacag
    37441 ctgcttctgg ttcagcttcc catccattaa gctcagcaaa ttctccttct aattcagctg
    37501 ctcgaatacc atcttcgtca gtgaaatcct ctttcatgta aatcgcatct ttttctttca
    37561 gcacttcata cagacgcttg tgtcccatga tgactgtttc aagtacagta tagtcttcat
    37621 agtcgtaatg gttctgtttc aatacggcca tccgttcatc tggtcccata gtaacggaac
    37681 ctgtggaagg ctgcagatcc cctgataaca ctttaaggaa cgttgattta cctgcaccat
    37741 ttgcaccaat caagccatag cagtttccgg gggtaaattt aatattcaca tcatcaaata
    37801 gtttgcggtc tgaaaagtgc aaactcacat catttacagt aatcaatttt tttcctcact
    37861 tttatcatta ttagttttga caagtcttat agaattatat aggggaaagg taaaagattc
    37921 aaggcaatcg aacattcttt gtgtttcacg tgaaacagaa tgaaaaaaat aaaaataaaa
    37981 gcggagcgaa aatagctact ataggattta ttagtttgca acagcataat ttttgacgtt
    38041 atttataaga gggagtacta taaaactgta aaagaaatga aagaaggatt gaaaatggat
    38101 gaaaaaagaa ccatcgactg gggctcattg attttgggaa ttttatttgt acttgtctca
    38161 ttgttatcat ttcaagaccc tgtcggaaat ttagttgcaa ttgtagtagt ctttgcgatt
    38221 tttgccttta ttaaagggat atttgaactg tttgtacgga acagattaaa agagctaaca
    38281 ggatataaag gaaagatgcc cttaataatc gggatcatcg atattctagt tggcgtcttt
    38341 ttcttattca atattggtgc aggagtcgca gcattgcctt ttgtttttgc agtatggttt
    38401 attgctgatt cagttttagc gttatttact gctgacttgg caagaggagt aagtgaagga
    38461 tattattggt ttacgatcat cgtcaatatt ttaggaattt tattaggaat tttcttattg
    38521 tttaatccaa tttcttctgc gttgacatta agctttttag ttggattcta ttttatgtta
    38581 tttggtatca cacatatcgt ctatgcattt agataagtaa aatcaaacaa ataaaaaagc
    38641 cggcttccga ttacagtttt actgttgtaa ttggaagccg gcttttttat catggacaaa
    38701 tatgcacgag gtgattttta ggtgtcgaga caaatttatg caaaaatgtg agaagctata
    38761 tacacaaatt ttatcttaat actcgaagca tagcgcagtt gtcacaacct cttttcatat
    38821 aattcattca atactggcaa atcatggact tcatattttt ctttgaatgc ttggatttct
    38881 tcttcagaat attttcttgg atctaaatgc agatcttcta ctggcaatgg gtgcttgtta
    38941 ttgatcttca catcgattac tacaggacga tctgattttg cagctgcatc aaaggcaaat
    39001 cgaagttgcg agtattctgt gactgtaaag ctatttgccc cgagcgcttc tccaacttta
    39061 ccgaaatctg catcttctaa aaatacacca aatttctttt gttccgtatc ttcttgttct
    39121 gcttcgatga aaccaaaaga atcattcgaa aagacaacat taataattgg aagctgatat
    39181 ttgacttgtg taatgatatc ttgcatgacc atagcaaacc cgccatcacc acttaaggta
    39241 aatacttgtt tttctgggta gcttagttgt gcggcaattc ctcctggcac accattaccc
    39301 atagttgcga accatccaga tgtcgtatgt ttttgtttac cgttcatatt caataaacga
    39361 atagaatgga tagtcgtgtt accgacatct gtgacgaaaa tcgcatcgtc ttcagcaata
    39421 cgattgattt ctttatagac agcctctgga cgaatcggtt cttcctctcg atcttcaaaa
    39481 gatttcaacc aatttaccca tttttcttta ttttcttgat ttgctaggta ccagctatca
    39541 gcagggcgag catcccctaa ctcgacaagt ctttgcaaag ctgtgtttgc atcaccgagg
    39601 atcgacaaag atgtttcatg gcgtcgtcca aattttgacg catcgatatc gatttggata
    39661 aattcagcag ttggattaaa aaatgcacgt ccaaatggga agtcgctacc gacaaataag
    39721 atcagatcgg cttctgccaa tgcttcattt ccgggtttag tagcgacacg tccagcaaaa
    39781 ccaagaaagt tttcataatc atcaggaata attccttttg ctagaacgga agcgacaaca
    39841 ggaactgaaa aatgttctga gaattctttg atttgcggaa atccgtttcg cgttccttga
    39901 ccaacataaa gaactggttt ttttgctttt tcaagataag gcaaagcagc tagcaaatct
    39961 ttttcttctg gtaatatcac acttgttttg tgagtgtgag cggtggagaa aggttgttcg
    40021 tcaatttctt caaaaccaag atcaacaggg atagtcacga tagccacgcc tttatgctca
    40081 taggcggctt taatggcttc atctactaca tgcggaagac tttgtggtgt catgactgta
    40141 cgattgtata cgctaacatc tgcgaaaata ggattttcat tagttcctgg aaagagttat
    40201 agttcatgga tgtagaagca acttgtccta agaacgctac tagaggcaca tggtccatct
    40261 gtgcatcata caaaccattg atcaaatgtg tcgcaccagg tcctgcagag ccgaagacag
    40321 cgccgacttt ccccgttaat tttgcatctg cagcggctgc gagtgcgccg acttcttcat
    40381 gacgaacttg aatgtagttg atttcggttt tttcttgata tagcgcatcc ataattgaat
    40441 tgaaagatcc tccgggaatg ccgtaaatat ggtcgatacc ccagctttca agaactttta
    40501 ccattgcgat tcctgcattg atttttgaca tggtgtttca ctcctttagc aatgatgata
    40561 cataaatttt ttgtatctag agtatagaac tttttatcga aaatcccaac taattcgtct
    40621 tttcacaaaa atgtagtcat gtttttggga atatgctaga gtagtacata gatagattca
    40681 agagagggga atggcatggt tgaatggcta ttgagacttg aaccttggca gcaagcactt
    40741 gctgggacag cttttactta ttttatgaca gctcttggtg ccgggttggt ttttttcttt
    40801 aaagaaatca aaaaagaagt gctaaacttg atgttaggat ttgcttctgg tgtcatgatt
    40861 gctgcaagtt tttggtcttt gttagatccg gctattacaa aagcagaaga aaatggagat
    40921 attgcttggc tagttgtaag tattgggttt ggtttaggcg gtgtgttttt atatatggca
    40981 gataaaacac tgccccatat gcattttgga ccacaacatg aagcagaagg attgcctacc
    41041 catttaaaac ggacgatctt gcttgttttt tctattacat tgcataacat tcctgaaggt
    41101 ttagccgtgg gggtagcatt cggtgcagca gcaactgcgg ataatccgac agccgctata
    41161 ttagccgctg tttcggtggc gctaggtatt ggtatccaaa acttcccaga aggagcagct
    41221 gtatcaatcc cgttgcgaca agaaggtctg agtcgtaaaa aggcctttgt ttacggacaa
    41281 gcttctggaa tcgttgaacc aattgctgga gtgattggag cgctactagt aacgaaagtg
    41341 gagctgctgc ttccttatgc acttgctttt gccgcaggag caatgattta tgtcgtggtg
    41401 gaagaattga tccctgaagc acagcagaca ttgtccagca aacgtcattt tgcagttttt
    41461 ggcgtcatga gtggatttat cattatgatg attttggatg tggcattagg ataaataaaa
    41521 aaaatatata tgatatatca aatagggccg cgaacttata tcgcgaccct atttttttag
    41581 taagttatat cataatgaag tgaatggtat catacattaa taatagtttt ttctatgtgt
    41641 atttcctttg atccagcgaa caagccagat gataagtgcg attgggatta gaactttgac
    41701 cgcaaaccat aaaagcccgc ttaggacact gacaaaaaga ctgatgacga agctagctgc
    41761 aattagcact aaaagaacca tgaagatatt taagaacata tttttttgac gcatacaaaa
    41821 ccctcctctt gttcattctt tactatagaa aaagtataac agggattgtt taaaaacacc
    41881 tccaactgaa gactgatttt tacttcatct acttaaatga tcaaacaatt gctttttctc
    41941 tggtttatca tctaaaatag agcggaaaag gaggagaata tcatgcctaa aaatcgtctt
    42001 gaagcattta cagatgctgt aatcgcgatt atcatgacta ttttagtttt agaacttcat
    42061 gaacctaacg gagacacgtg ggaggcgctc gctgcattag gttaccgatt ttttatctat
    42121 attgtcagtt ttatcatttt agcgatttat tggaacaatc atcatcattt atttcaagtt
    42181 gtacataaga taaatggacg ggtcttatgg gcgaacagtt tctttgtttt tgcgctttcg
    42241 ctttttccgt ttgcaacttc atggatcagt gagtacatca atagcctggc tccagaaatg
    42301 acttatggtt ttgttacctt gaccgctaat attgcgtatt atatcttggc aaaagaactt
    42361 gtcaaagcaa ataaaggcca cgagaaagca ttgaaggcga tgttgaataa ttacaagaaa
    42421 tcgtatctat cgattggttt gaatgtgtta ggaattgtct tagggtattt agtagcgcca
    42481 gtagccgtgc tgatcgcaaa catcgtgatt ctagctgctt ggatcatccc aagtcgtacc
    42541 atcgaatcac aatatcggta aaatgatccg tgtttaaaat ttaagagaaa aatatagaaa
    42601 aaataaataa acgatcaaat atccgagtga tactagtatt caaagaggga tgcagatgga
    42661 tcaaaaaaga attcatgtag gactgattac tagttttgtc acgatgctta tttatttgga
    42721 tcaaggtcat ttgacttgga cagtagttgg tgtcgtagga tttttgacat tattcacagc
    42781 aataaaaaaa taaacatctt tatgtaatct gatgttctat ctatttaaga aaagcatgtt
    42841 tacagcagta tgattctgtt gtaaacgtgt ttttatttgt ggaaaattta atttttagaa
    42901 aagtgtatcg aaaaatagat agttagtttt tccacagtgg ataacttcgt aagagataaa
    42961 aataaaaaat tagtcaaaga agggcgtata gatttctttt gataggagat atacaacaga
    43021 aatgaataaa tattaacgtg ttttcaaaca gtataaaacg gtgtggtttt tggaataaaa
    43081 aaataacata tctcatttta cgcttttgtt attttatact taaaaaataa cgacacagaa
    43141 aataccgtgt ctcagatttc tctactactt ctaaaaacta ctgttttttt cctttgaaat
    43201 gccttcaaaa agtaggatca ggcagaatat actggcagaa tcaaggagaa gggagcctaa
    43261 ataaggagaa aaaccataga aaatataaag taattactta taaaacaagc tttttataga
    43321 aaaataatat acctgagtag ggtataaatt aagacggaat tcctttctag attgagatat
    43381 tgactaggaa gaatgttaag attttaagcc tttaagctaa aaaaaaaccc tttttgttaa
    43441 ataaggggaa tatagcctgt cagtttcaaa ctgcaagtcg tcctgctgca ataatatagt
    43501 agattagaga tgaaaataga tttttttaaa ccaatgactg aataaaaaga ccgtcataga
    43561 tacacattgg aatgtgtcta ttacggtctt tttttacgaa cgattttatt gaagacggac
    43621 agttcgggtc aaaaataaaa aagctacgat cagaaataag aataaaatgt atcccaaaat
    43681 aatggctaga cggtctaact tatttgtcga tagatgtttg tttagaagtt gataggccca
    43741 taaacctatc agtcctcctg ttgtattagt tatcaaatca gtgatgtccg ctacgccaat
    43801 accgaatagg aattgaatca attctgccaa gaagcttaca aggaaaataa tccctaattt
    43861 tttagaaaaa gaaagtctct tgaaattgac attcaaaagc accccaaaag gaaaaaagac
    43921 aatcaagtta taagtggtct cacgtaatac cgtcgtattt tcaaaagaaa aagtagaaaa
    43981 agggacgaga ttgacattgc tgtaagaata agtgagaaat tgtggaagat taaatgatag
    44041 cttgaataaa atcaaccata atagaaagaa taaataaatc cctaataaaa attttgatac
    44101 ataccgcata gacatctcct ccatttaaaa agtataccat cgaaaaccgc tgaaaaatca
    44161 taaaaaagta tgaagtttaa ggaccaacgt agttatcgta cgaaaattag aagctttttt
    44221 ttgttgggaa tccggtttct ttaacaaagc taagatagcg agttgcttgg aaaagttgct
    44281 atcttttttc tgtcaaaacg actcggaatg ttcgtttttt gttctaattt ctccaagttg
    44341 tttacttttt gatactaagt ttatgaaaaa tcaagaaata gttgttatac taggtaatgc
    44401 tgacaaacgg gattggcatt tcatcttggt tcagcttttt ttccaattac taggaaggag
    44461 ggatagattg ttcaagactt attttcgttt caataaaata caagataatc cttttcgtat
    44521 catgaatctg atgctactta tctttattgt attatggtta ggttacataa atcatgattt
    44581 tttgatttca agtttttcat cattagggat ctttactttt ttctattatc aaaacatacc
    44641 gatgaaatat ttgctgaaac gtatgtttct gatcggttgc ggactgttgg ttgctttcgt
    44701 tttggggatc ttatcgactt atgttttatg gcttgaacca tttgccgtag ctttggttgc
    44761 tttttccagc agattcgtgt tgcgattatt ccatatttct aaaccaggtg gcttgttttt
    44821 tgcgatgctt tctgccatgg gaacgagcat gcagctgcca atcgctcaat taccgatcgt
    44881 ctcactttat ttttttatgg gtgtcgtttt tgccctgatt gcggcagtga ttacaaaatt
    44941 actggattca cggcctgagc agacaattga aaaagcaact ttaaaagaaa gatttcacga
    45001 agagccttta gtgatcattg attctgtttt ctacagcgct gccttatttc tttccgttta
    45061 tgtcagtcac ggcttgaatc tgcataatcc ttattggttg accttgtcat gtgcatcgat
    45121 tttgctagca gaaaacttgg atgcgatgaa gcatcgacaa gtccaatatc tgattggatc
    45181 gatgggtggg ttatgtgtgt cggcattctt gtcatttgtg ccgtttacgc agttgcagac
    45241 catttttctg atcacttttc tatatggaat cgcacaattt ctagttgcta gaaattatgc
    45301 agttgctaat atttttctta atccgatggc gttgatgcta tctacactta ttcgtggagc
    45361 atacttgatt tctttgatcg aatatcgttt tttagggatc gtcataggaa gtttcatcgg
    45421 tttaggtgtt gcgtgggtaa tgacggttgg tttgcaacat tatttaacgg ttgttcgtca
    45481 aaaattagaa tagaaggaca aatatatgtg ccaaaagagg ttatgacaag atttttgtca
    45541 caacctctaa ttcaaggtgt tcaaaagcca gattctcagc attaagtcaa attcacacaa
    45601 aaatgtggaa aggaactttc aaaaaaattt tatatttatt ctatcaaaaa attttatatt
    45661 tattctatca aaaaattttg tttatgatgg taactgaata aactttcctg agatggtcaa
    45721 tgctttcctt gaaagtctta cagatattct ttcttcatag aaagtttaag ttttatagtt
    45781 agtgtacaat aaaagtatgt ttataccata tggtgtccgg ataatcagtc atttaaacaa
    45841 tgaggttcaa agatatgaaa aggggaaatt tgatgaagaa aataagcaat gaaatccaaa
    45901 ttctggcaga aactttaact cttcccaaag tcgttataga gcaaatgatt gtacaagcaa
    45961 aaaacatcct tgatgaggtg tttgagcaat atagtcatga actaatggat cctaataaag
    46021 caaaggcgac tgcaaagaaa atagacaaag tctatgaaga ggaacctttt gcagcattag
    46081 ctatttatct atatgcagct tctcaaagtt ggaaaaaaat ttatcaacca ttgaagattc
    46141 caagaactat ctatttggca acaatgaatg cttttactag atttattcat gaacatttcc
    46201 aagtaacagg aagctatcgc tttgaccgtg gtttttggat ttggcattac actagtggct
    46261 tgatctttcg gattggtgaa ttggagtacg aaatgacata ttttccgaaa gggtacacgg
    46321 atctaagatt agaaggaaag cagtgccttt ctcttcatat tccttccgat gcagatttat
    46381 ctcagaataa gataagagat agttacgaaa gtgccattcg tttttttgaa ctttattttc
    46441 ctgattacca ttaccaagtg atgtacacag atacttggtt actatcaccc aatcttacta
    46501 aatggttgaa aaaagagtca aaaatctgtc tttttgcagc cgattatcga ttattatcag
    46561 ttgatgaaca ggacgatagt ggagtccctt ggatctttgg acgagtagat gcccaaatac
    46621 atgattatcc agaaagtacg agtttacagc gacaagcaaa agagcaattg cttgcaggcg
    46681 agcacattgg ctctggctta ggtattctta cttcataagt ttagtacttc gaaatagttt
    46741 aaaagagcgt gagacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac
    46801 ggcggaagca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat ttgaaaagca
    46861 attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag cctctttttt
    46921 agtgttctat cgaacacaca gtacgttcaa taggtaaact agctataaca atagatatta
    46981 aagttaacgg acaagagggc cttttttagg tagctaaaac gtaataatga aaatttattt
    47041 ccagagatag gagtcaatca gctagtctga tcgactgttt taacaagttg actttcattt
    47101 taacttttga taccatttaa aacacaaatc gtaattgttt cgatttgtgt tttttagcat
    47161 gactacaatc aaagaagaaa gtgggtcgtc catatggaaa aaacagatat ctcaagtgca
    47221 taccgccgct tgaaaagccc aaatatcaaa acacgaaaac gtgcgctgaa gatcatcaaa
    47281 gatgtgaaac ggaatagtgg gaaaaggtaa gaagaaggaa acttaattaa aaaaatagcc
    47341 gaaaaacgtt tttcggctat tttcaataat cggtttttgt gtaaggtttc cgaaagaact
    47401 gctgttgatt ttccattttt aacatatgat aaattggtag aatctttctt ttcaaattga
    47461 taccattccc taattccagt tatatagtta actacagaac cacaaagcac gtacgtttat
    47521 aaaagtatta tctgtagtta tttttcaatt ccctttcaac ctcttatttt gaccagtagt
    47581 attgatcact ttacctttta acacctttgt tcgtttttga aacattttta gtcaagaatg
    47641 gaaacgtaac tacataatca aaggttttgc gaaatatttc atgaaatatt tcatgtagaa
    47701 gcgagcaata cggttgcaaa taaccattat cgtttaataa gcagttacga aagctcccaa
    47761 tatctctaac gttcagctca ctccatttct tttcttcaaa aaaatcagtg attcgtatct
    47821 ctttctattt gtcgaaaaag ttaactttaa aaagtaacgc cgaaaaaata tgcaaaaaaa
    47881 taaaaaagca gttactattg ctagaataac atcaaggaat aataagtttt ggttttcaga
    47941 taatagtcga taagttgtgt attggaattt tagatacagt aataaagtat ttttcatgaa
    48001 attttgtgag aatcactatt acaagtatct ttaataaaat taatggttaa ggaggaactt
    48061 aaagtagaat gtaaatgaat agttgtagtc agtcgattgt gatactagac tcaaagttgc
    48121 aggaataagt ttttcaattt gtgattggaa gataaaaaat gaaaaagaag ggcttttttt
    48181 tatactttgt tgattgtagt gtttattttc cctctgttta gccaagtaac attttctatg
    48241 actcaaccag tttcaagtga ggaacatgat aacctttttc gtgctacaga agagtttaag
    48301 aaatatcagg aaaatattgt tccggagact ccattagcta gtgagccaat tactgatatt
    48361 gatggaaacc aaataggatg gtatatacag tacgaagtta tggtggtaaa taatgactca
    48421 atagtaaaaa atacagtagg cttagagcta acaccgattg aaaaggtgag ttcattgtta
    48481 acgtatattt atactgatga aagtgacgag actgagatca ttttaacgga ttactcaaaa
    48541 attgctactg ataaaaagta tatattgtgg atgtagacac tagtgaaata ctttatgata
    48601 tagaaattga tgaaaattta ctagatgtag cacaagaaat cgatcatcaa aagcaggaag
    48661 ctattcgata tgctggtaga aaagggaaaa gaaaatattt attacgtgaa tgtagcaaaa
    48721 gttagagaag atgaaaatga gtggaaagaa ttcaagagtc gctactcaat taactcgact
    48781 ccgacattta cagtttacag agaaggatcg atagaaaaaa ctgttttttg gactaaagaa
    48841 agtggaatgt ctttagctga agtagaagag tttttggatt atgttagtat gcaacagtaa
    48901 gggagttctt attatgaaaa attttgacac atattatgtt attgtttttt cgatatcttt
    48961 gctgttaata ttactaactt taatgcagta taaagagtat ccagagtatt ttattttaac
    49021 ttttgtatat ttagtaagta gctacacact tctatataaa ttcagaagtt cttctagagt
    49081 ttctaaagtt tgtttcttaa ttagcttatt gattctataa tatttttgat ttatatagga
    49141 aattaaaaat attatagaat caacactcag agaacgggtt ggtttttaat agatttaata
    49201 agtactgata atgaaatttc tcctggttgg gaaaacgaag ttggttaccc tgtagaagaa
    49261 ttttttcaag attactttgc ggagtatgcc gataggataa tgagagatta cgtaacagat
    49321 aaaactcaag aagtcatcaa tcaatcccag tcattaaatg aattatctga taaggcgaaa
    49381 gaagaagcag ttgccattat ttcttcaggg attagtgact atattgatat gagtggtgaa
    49441 atcaattatg gcgataaaga caaaattgta cgcatgataa aagcttttat caaaactttt
    49501 gatgtgaagg cagatcttaa gtttaatgat acttacctag taggaaaatt aattaatatc
    49561 cttgggacag agaaagatac ggaaacgttt atttcctctt tgtctatgtt gtttacagat
    49621 aagcattttt caactcagct tggtggagag gaactagtgg aaatctttta accattacgc
    49681 ccagcattaa taaaagtata tcaaaaaagt actcctgatg atttttaaga ttggtttgag
    49741 aaataatgtg aaaacactat ttttaatgtt aattatagat agagatgaac gcgtcatatg
    49801 gttaaaagaa tgaaaaagtc aaagatacac tgctatattt cactaaggat atagcagtgt
    49861 atctttcatg tcgtttcact ggcagttttt tataaaagga ggtgtgcatt tcagttgctt
    49921 ttctttggta gttagttgaa tcgtttaaga attaacggat gtggcagaca ggtgctctgt
    49981 ccaaaaacca gtaaaatctt tgatggttcc atctttattt agctgtgcct gttcaaatac
    50041 tgttttgttt ttaccgaatg gatcaattgc aataattgtt ccgatccccg cacgtttggc
    50101 agcaagtaat cctgagtaag catcttcgat aacaagacaa tcagccggag ctaagctcag
    50161 tttgtctgcc gctttaagaa aaatatccgg ttgcggtttc ccagggaaag agccgtcgtc
    50221 atagacaatc ttgtcccagt caaaccagcg ggctaaatcg aaaatatcaa aataaaaagc
    50281 aacattctct ttgacagtag ccgtggcaat cgttaatgga atctgttggt cagtcagctg
    50341 gtcaagagtc gcttcaagcc cttttgtcaa ctgaagctcg ttttcatttt gcaagcaaag
    50401 catacgataa tagctttctt tttcttctga caatacggcg atctcagagg cggtcaaatg
    50461 ctctgaaatg aaatgtttca aaatctccgt attcgtccga ccatgaatat tttttaaaat
    50521 atcctcgtct gataaaccat cttttgtatg atcatgtatc atatgcagcc aagcagcttc
    50581 atgcagatga gagtccaaaa acattgttcc gttgaaatca aatataatcc ctttcatagt
    50641 tacgctccta tagtggtatt ttcggttgaa tcagcaattt gcagatcgac atattgtgca
    50701 tagtgctctt gaacctcccg cgagatctgg cgatccgtaa tgagcagatc gaaatcatgc
    50761 aaattataaa acacataaaa atcatctcga ttgaattttt tattatcaac gagtagatat
    50821 ttcttacggg aattatttag agcgatctgc tgtgcttctc cttcttcggt actgtaagta
    50881 gagatcgctt cgttgtgaac gccatttgaa ctgataaatg cttttgtaaa ctttagtctt
    50941 cttaaattgt cgttggtgat cggtccgaca aatgcgccgg tatttttccg gaaatcaccg
    51001 ccaatcagta gaatttctgg tccatctgct tgagcaagaa tatcaaaaac tggataatta
    51061 tttgtaatga tccgaatttt cttgttcagt aaatgcgtcg ccaatagttc gattgttgta
    51121 cctggtccta agaaaatcgt ttctccctcg tgaatcaagg aggctgctgt ggcagcaatt
    51181 tctttttttt cttgaatctg cagagtggct ttttcagtgt gagaaagttc ttgatctaaa
    51241 gtgtaggaaa gactttgagc ccctccatgg acacgcagca gcttgcccga tttttctaat
    51301 tcatctaaat ctctgcgaac ggtcatatca gaaacatcta attgattgat gatttcatta
    51361 acggtaagga ttcctttttt attgaccatt tctacgatag taagcaatct ttcttttttc
    51421 aacattgtct tcacctctaa tttaaggata atctatcata taaacggaca acagtcaatc
    51481 taattcgaac aaaagtaaac atttagggtg gtttttatgt ttgttacaat agattttatt
    51541 gctgttttct ggtttttatg attatttgtg tttgtttttg ttgacaaatg ttttggatgc
    51601 gtttacaatg caatcagtta gaaagagcga aaactgatta tagatttgag gagagatgta
    51661 catgcttaaa ttaccagaag attttatttt tggcggagcc acagcagcct atcaggttga
    51721 aggagccact aaggaaggtg gcaaaggcgc tgttgcttgg gatgactttt tagaggaaca
    51781 agggcgattc agtcccgatc cggcaagtga tttttatcat caatatgcaa aggacattga
    51841 attgtgtgaa cgttttggtg taaatggtct aagattatcc attgcttgga gccgcatttt
    51901 tcctgatgga gctgggaaac caaatccaga aggaatcgct ttttatcatc gtgtgttcga
    51961 agaatgtaag aaaagaaacg taacgccgtt tgtgacgttg catcattttg atacccctaa
    52021 acgtttgttt gaccatggag attttttgaa tcgagaaaca atagaagcat ttgtttccta
    52081 tgccattttt tgttttcatg aattcaaaga agtcaaggtg tggagtacct ttaatgaaat
    52141 ctatccagtt gcaaccaatc aatatttgtt aggtgttttc ccaccaggaa tcaaatatga
    52201 ttttacaaag atcgtcgcct gtcttcataa tatgatggtt gctcatgccc gtgtagtgaa
    52261 ctatttcaaa gaaaacgaac ttccgggtga aattggtgta gttcactcat tagagacgaa
    52321 atatgcggca acagacgcgc cggaagataa gcatgctgcc tttttagacg atgcattgtc
    52381 gatccgtttc ttattagatg ctacctattt aggctattat tcaactgaaa ccttgactgc
    52441 tcttgatgag atatgtgaag caaatcaggc cagctatcat tttcctgaag aagatttcgt
    52501 tgaattgaaa aaagcatcca cgcgtaatga ctacttaggg atcaatcact accaatgcca
    52561 ttttgtcaaa gcttacgatg gagaaaatgc aatccatcat aacggtacgg gtgaaaaagg
    52621 gacctctgtt tataaagtga agggaatcgg agaacgtatt tataaagaag gaattcctcg
    52681 aactgattgg gactggctga tttatccaga aggtctatat gacttgttgc tgcgaattaa
    52741 aagcgattac ccacattaca acaaaatcta tatcactgag aacgggatgg ggtataaaga
    52801 tcagtttgaa gatggcatta ttatggatca gccgagaatc gactatttga gagtctattt
    52861 ggaatcctta agcaaggcga taacagccgg ggtaaatgtg aaggggtatt ttttgtggtc
    52921 gcttatggat cttttctcat ggacaaatgg gtataacaaa aggtatggct tgttttatgt
    52981 tgattttgaa acccagaagc gttacccaaa agaatcagct tactggtaca agttggtcag
    53041 tgaaaccaaa acgattattt aataagtgat aatggaggaa gaaaagatga ataaagagga
    53101 attacaaatg cttggttttg agatcgttgc atattcaggc gacgctcgca gtacattatt
    53161 gaaattattg aaagaagtaa gacaaggaaa ctttgaacat gttgattcgg cgttgaaaga
    53221 agccgacgaa aatttaaccc ttgcacataa ttcgcaaaca aaaattttag cggaagaagc
    53281 atctgggaaa gagatggaga tgggattcat ttttatccat gggcaggatc atttaatgac
    53341 cactttattg ctgagagatc tgattcaaga ctttattgta ctgtacagac agaatcaagg
    53401 ataggagaag aacgctatgg atggaatcat taaacaaatc gaaaaaggga aaccattttt
    53461 tgaaaaaatc tcacgtaata gttatttagg agccgttcgt gacggatttt taacagcgat
    53521 gccagctatt ttattttcaa gcattttcat tttgattgct gcggttcctg agatttttgg
    53581 ttaccaatgg cctgaatctg tctccacatg gctatggaaa gtctataatt attcgatggg
    53641 tgttgtaggg ttactcgttt cagcaaccac tgctcgctgc ttggctgatt cgatgaatcg
    53701 tcgcttaccg aaaaacaaag taatcaacac cacctctgtg atgctggcct ctgtggtaag
    53761 tttcctgttg ttaagcgtct ctccgattga aggtggattt tcaacggaat atatggggac
    53821 aaagggacta ctggcttcct ttgtcgctgc atttttaaca gttaatttat ataagttttg
    53881 tgtgctgaaa gatattacca ttaaaatgcc taaagaagtt cctggaacga tttcgcaaac
    53941 cttccgagat atttttcctt tctctttttc agtatttgcg gccgttttaa ttgatttagg
    54001 cattcgacaa atcttccaaa tctcatttgc agaagcaatc attacggtgc tgcagccgct
    54061 atttacagca gctgacgggt acttaggaat cgctattatc tggggagcga tggcgctgtt
    54121 ttggtttgtc ggtgttcatg gaccgtcgat cgtggagccg gcaattgcgg caattatcta
    54181 tgccaatgtg gaaaccaatc tgcaattgtt caattccggt gaacaagctt ctaaagtact
    54241 gacggtgggt ttagggaatt ttgtaggaac tatgggagga actggggcaa cattggttgt
    54301 tccttttatc ttcctactct ttgctaagtc taagcagttg aaggcagttg ggaaagcttc
    54361 ctttattcca gtaagtttcg ctgtcaacga accattgcta tttgcggcac ccatgatttt
    54421 gaacccttat ttttttattc catttttgtt aacacctgtt gtaaacgttt gcctgttcaa
    54481 gttttttgtc gatgtattgg gcatgaacag ctttatgtac gttttgcctt gggcaactcc
    54541 agcaccgatc ggtttggttc taggaacggg catgggtatc ttagcttttg ttctagcagc
    54601 ggttctaatc gtcgttgact tcctgatcta tctaccattt tgcaaagcat acgatgctgt
    54661 cttagtagag aaagaagcac aaaaagcaga ggtgatcgca accgaggaag gtgcttctgc
    54721 cgatgtacgt gaggaagtac ctgtggcagc gagtcaagtt atcagcgatg caaataaaga
    54781 aatcaatgtg ttggtacttt gtgctggcgc agggacaagt gcgatgttag ctaatgcttt
    54841 aaaaaaaggt gcatctgaat cgaaagcacc gatcagtgca atggcgggtg cttatggttc
    54901 tcattacgaa atgctgcagg attttgatat ggtggtctta gcaccgcaag tcaattctta
    54961 ctatgatgat atcaaagaag acaccgatcg cttaggaatc aagctggttg cgacaaaagg
    55021 agcagaatat atcggattaa cgagagatcc tgaaaaagct gttcagttta ttctgaacca
    55081 atttcaataa aggaggagcc ataatgaaaa tgggaatttg gttgcgtaaa gctgttttat
    55141 ttgcagctgt gttaggggct ttgggggctg tttcaaaaac tgttgaagca tctgccagcg
    55201 aatttattcg cggagcagat atttcgatcc tgtcagatat ggaaaaatct ggtgcaaaat
    55261 attatgaaga cgatatttca aaagatgcct tagagatttt aaaaaataat ggtgtcaact
    55321 atgttcgact gcgtttgtgg caggatcctt ataatagtaa tggagaaagt tatggagcag
    55381 ggacaaatga tctggaaacg acgattgacc ttgcaaaacg agcaaaaaat ctgggactta
    55441 aggtgctgct ggattttcac tacagtgatt tttgggttga tcctgggaaa cagaatcttc
    55501 ctaaagcatg gcaaggtctg acctttgaag aaatgaatac ggcattgtac gactatacaa
    55561 agaacgttct gtcggaaatg aagcagctgg acgtttatcc tgatatggtt cagatcggca
    55621 atgaactgaa tagcggaatg ctctggcctt atggcaagtc ttggggagaa ggcgggggag
    55681 aatttgatcg attggctgct tttttgaagt ctggtatcca agctgttcga gacactcaac
    55741 ctaaaacaac tccagtaatg ctccacttag ctgatggtgg cgatacagga gcatttactt
    55801 ggtggtttga tgaaatcacg agtcgaggtg tgtcatttga tttaattgga gtgtcgtatt
    55861 atccgtattg gcacggttca atgaatgaac ttcaaaccaa tatgaatgcg atcagccaac
    55921 ggtatggtaa agaagtgatc gtagttgaaa cagcttatgg gcatacaaca gcgaatgccg
    55981 atactatgcc aaatgctttt ggtgaagccg aagcagctgc ggggggatat gaaccaacac
    56041 cgacaggaca agcagagtat ttgctggatc ttgccgatcg gattcaggca gtaccgaata
    56101 atcgcggggc gggcttcttc tattgggaac ctctttggta caacggaaat gtgagttggg
    56161 caacacaagc aggtatgaat tatctcagtg ttcaatccac tatgggaaac gaatgggaca
    56221 accaagcgat gtttgatttt gctggaaacg ccttgccaag cttgcgtgcg tttaaacaag
    56281 caggggcgca aataaatcta gttaaaaatg caagtttcga aagcgatgga ccaacgacca
    56341 gtccttccaa ttggcaaacc tggtttcaac aaggaaccgc taagggtacg atcaaaacgg
    56401 aagcgggcac tttttttggg gactacaaac taactttttg gcaggatcaa gcatacgagg
    56461 catcagctta tcaaaatgtt agtggcataa gcaaaggaac ttacacattg agtgcctatg
    56521 taatgtctgg gggagagttt gatactaatc agttatatat caaaaattat ggtggagcgg
    56581 aactaaatac tgcggttgtt aaaacaagtg aatggacaaa aattacaatc aaagacattc
    56641 caattacaac aggtgtttgt gaaattgggg tttatagcaa ggcttcagga aatgcttgga
    56701 cgaacgttga ttttgtttca ttggtgaaac aatagactgc ggatcgtttc gattcaagat
    56761 cggaggttcc cttcagccac atcgttagcg tagaaggcag gaatcgaacc tgcacctcgc
    56821 ctttgccaaa aataaccaga aacgatttcc agtcattttt accaaaacga gtaaagcacc
    56881 agacttcatc tacactttgt attatgctaa agagagttca acgatttcgt aagaagcaat
    56941 gaaaaaattg caaaaagttg tgcagataac ataaagtttg tttaagaaag ggtaacctta
    57001 gaattccgtc gtgaatatga tttgagcact tagatggata gaaaaaagtt ctcggaaaac
    57061 agttcgtttt tcgagaactt ctttttatga taagaatgaa acaaattaac ttatattata
    57121 gtctcttttg gtagggaacc atcttatttt taatgaaaat caagcatttt agctattgaa
    57181 gaatgttgat ttatagggat tccccctcca tattatgttg gctctttatt cccactctgt
    57241 tttcaacgta aagtgtataa aacagaatgc gatactatca agggagttaa aacaatatac
    57301 agaacagtaa aacactataa ataaaaataa aagtgcaatt tttgcaccta atcatactct
    57361 gtttatatat gaaaactaga ttctgaatcc aatatttggt taacgagagg cgttcgaatt
    57421 tgaacgtctt ttatatatta ctttcaaata aatatgaggt agaatactat ctattttctt
    57481 tttaacccaa ttgttataat ggagagtgta aaatattttg tgtaaataga aaaaaggaag
    57541 tcccttctgt agaatagagt taccacaaca cattcacaga agagaggact tccctatgaa
    57601 cgattttact acagaaattc taaagactct agcgaacaaa ggcgatttga atgaattatt
    57661 ccgtgtccat ttggagaaag cagtcaatac gcttctcaaa acggagttaa cggctttcct
    57721 agattacgaa aagtatgatc gcattggttt taacacgggt aattctcgta acggctccta
    57781 tgaccgtacg gtcaagaccg agtatgggga acttcatctc cagattccgc gcgaccgcaa
    57841 tggtgagttc aagcaacaga ctgttcctgc ttatagacgg acgaatgaca cgttagagga
    57901 gaccgtcatt cacctcttcc gaaaaggtat taccatgtcg gaaatcgcag acttgattga
    57961 gaaaatgtat gggcattact acacgcccca aaccatgtcc aatataacaa aatcatttac
    58021 agaagaggta acggcgttta atgggcggga gcttcatgac cgttatgctg ctatttatat
    58081 ggacgcaacg tatattccgt taaagcggaa aaccgtcgcc aaggaagcta ttcatatcgc
    58141 agttggcatt cgcccggacg gatcaaagga agtattgagc tatgcgattg caccgactga
    58201 atccatcacg atttgggagg aaattttatt ggaccttcaa gagcgcggtt tgaaaaatgt
    58261 cctcctgttc atcacggatg gcttaaaggg gatggtagga gcgattagtc ggttctatcc
    58321 caaagctcgt tttcaacatt gttgtgtaca cgtttcccgt aatatcagtc ataaagtgcg
    58381 tgtcgatgat cgtaaggaag tctgtgatga ttttaaaatg gtgtatcaag cctcatctaa
    58441 agaggtggcg ttggaagcac gtggtacttt tgcggaaaaa tggaaaacca gctatccaaa
    58501 agtggttgaa tcgattcttt cgaacgatca cttgctcact ttctatgatt tccccttggc
    58561 catacgcaag agtatttatt ctacgaactt gattgaatcc tttaataaac aaatcaagaa
    58621 atacagccac cgcaaggaac agttccaaaa tgaagagtcg atggaacgtt tcttagtctc
    58681 gtcttttgat acttacaacc aaaaattcct aggtcgcagt cataaaggtt tccaacaggc
    58741 cgaaggcgag ctcgaacaaa tgctaagcca actgattgag aattagaaac aatctgcagt
    58801 agggaagaat catttacaca aaattattga cgctccctta taatgagaac ttttactaac
    58861 ataatttatg ataaacttac tatataatca tattaattaa atagttagga gatctgctta
    58921 tgtttatatc tactcttcaa attcgaaatt ttagaaatta tgaatccgaa atctttcgat
    58981 tcgataatga gacaaatact attataggtg agaatgattc agggaaaacc aatgctctta
    59041 ctgcattgag aatcttatta gatgatagtt attactatag tagtaaaaca ctaaaagaat
    59101 cagatttttt tcatggaatt caaaatgggt ggcaagggca ttggattatt atctctgcga
    59161 catttgaagg aatcagcgaa gaagaatttg acaatgagat ttgtgcttcc atttctttaa
    59221 attctgaaag tcaaacaatc ttagaagaat tgatttcaaa tgcagataaa ggtgtaggta
    59281 gtatttctct atttattaga cctaacaaag ctattagaaa gcaattattt gatatttcca
    59341 ctgaattaga ctctcatcaa tttaacgaat ttagaaattc tattcgtcta tccgactatg
    59401 aattttacta cacatctaaa tcaaatctaa atttctgtat caatgaaaat tatgataaat
    59461 tggtaggaag actcaatgac aatatagcta gtaatcctga agaagacgat gaagctctgt
    59521 tgggctcaag aattgacatg tcagatattt tcaagcatat ttcggttgtt tatgttgacg
    59581 ctcttcgaga tgttcttaga gaaatgaaaa acaatcgaaa cccagtcaaa agaatcatgg
    59641 aaacaattga atcaaaaata tcatcagata atgttgagtc attaaaaaca attatacagc
    59701 aattaaatga gactattacc agtgttcctg aaattaggaa aattggcgaa aatattaatc
    59761 ggcaactaaa tagcataatt ggttcagtgt attctcctaa tcttcttctt tcctcaacta
    59821 tgtcagatga tatgggttct ttagcaaaat ttctttcaat gaagccagaa caaaatatcg
    59881 acttagactt actagggtta ggacatctaa atatgattta tttagctttg aaaatagtcg
    59941 aatttgaagc gtgtcgttca agagaactac ttaatattat gttgattgaa gaaccagaag
    60001 ctcatattca tcatcatatt caaaaaactc tgttcgaagg attaaatctt caaaaaaact
    60061 atactcagat tctcatgacc acacattctg tacatttagc tgaagtgtct gaaatatctc
    60121 ggatgaatgt attaaaatcg tttaatggca aatctatcgt tatgaatcca gcaaataatc
    60181 tgaactcatt tgctaaagaa aagttaaaaa agaacaatct aaatctaata aacgcagtag
    60241 agagatattt agatgttaaa agaaatggat tgcttttttc taaaggtgtt atcttagttg
    60301 aaggagatgc tgaagaaata cttattcctc aaatagtaaa aaaattattt ggtataaact
    60361 tagacgaact tggaataggt ttgattaatg ttggtagtac ttcgtttgaa tatatcgcta
    60421 gcttgtttga cgatgataga atacagagaa agtgtgctat tgtaactgat ttagatgaac
    60481 aggcaatccc atcagaacat cgattgtata aaagcactgc acaagagaaa ggtcaagcaa
    60541 gaaaagaaaa attatcctcc ctttttaatg aaaacaattg ggttaattgt ttttatgcta
    60601 atacaacatt tgaaattgag tttttagatg tgaataaaga aaatattcta acttatgtca
    60661 gtccaattat agatgacgca ttcaaagata aaaaaacaat aactgcttat aaagaagaaa
    60721 tacaaagtga acaatattta gaaagaaatt tagcgatgtt aaaactagcc aatcatgttg
    60781 gtaaggggtg gtttgcaatt gagttaggtg aaaaaattga ctttttaatc aaaattccta
    60841 agtatattct taatgctatt gcttttgcat gtcaggaaat agtagatctc tcaatttata
    60901 aaaaaattct actccataca atcgacttgt acgaggaaac tacagaattg tcagctttat
    60961 cagctagttt aaaaacaagt gatacagctg atttgaatat agcaataatt tctttattag
    61021 agtactttgg taaagatgag gatgttgtgt atctaatcaa tcagatagaa aattacacaa
    61081 aaatacttta tgctgaggtt tcaaaatgac aaatatcttc gaaaaaatcg taaatgattt
    61141 aaatttagaa caaaaagatg ttgtggaaag tgaagataac ctttatgtaa atgcatgtcc
    61201 tgggagtggg aaaacaaggg tacttacaag gaaaattgct taccaagcaa ttaaacacga
    61261 tggatcacta aaaagaataa ttgctatcac atacactaat agagctgctg aagaaattaa
    61321 ggaacgccta agtttactta gtatagatga tgatattaat atttgggtgg ggacaataca
    61381 tcagttttgt cttgaattta ttatttatcc ttttaaaatg aatctctcaa gagtatcaaa
    61441 aggatttaca attattgatg attatactca aagagcttac gtcagccaaa ttaataatat
    61501 gctgaattta aatctcaaaa cgtatgaact gaacaaaatt gatttgtcac tttctcatga
    61561 ttttaaaatt aatgaagttc agtatactca agtttctgaa atgtatcaca ctatgttgga
    61621 aaaaaataaa gaaattgatt ttgatatgat tttactagta gcgtataaaa ttttaactgt
    61681 aaacagtaac gttgcacgta atattg
//
LOCUS       DAIGTA010000011        59829 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.011, whole genome shotgun sequence.
ACCESSION   DAIGTA010000011 DAIGTA010000000
VERSION     DAIGTA010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.011"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(450..1760)
                     /locus_tag="NOB43_000690"
     CDS             complement(450..1760)
                     /locus_tag="NOB43_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCI0981578.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1772..3190)
                     /locus_tag="NOB43_000691"
     CDS             complement(1772..3190)
                     /locus_tag="NOB43_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0981579.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3430..4998)
                     /locus_tag="NOB43_000692"
     CDS             complement(3430..4998)
                     /locus_tag="NOB43_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI0981580.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5002..5412)
                     /locus_tag="NOB43_000693"
     CDS             complement(5002..5412)
                     /locus_tag="NOB43_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HCI0981581.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5409..6332)
                     /locus_tag="NOB43_000694"
     CDS             complement(5409..6332)
                     /locus_tag="NOB43_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HCI0981582.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6329..7207)
                     /locus_tag="NOB43_000695"
     CDS             complement(6329..7207)
                     /locus_tag="NOB43_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HCI0981583.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7194..8530)
                     /locus_tag="NOB43_000696"
                     /pseudo
     CDS             complement(7194..8530)
                     /locus_tag="NOB43_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
     gene            complement(8533..9636)
                     /locus_tag="NOB43_000697"
     CDS             complement(8533..9636)
                     /locus_tag="NOB43_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0981584.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9710..11218)
                     /locus_tag="NOB43_000698"
     CDS             complement(9710..11218)
                     /locus_tag="NOB43_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0981585.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11184..11876)
                     /locus_tag="NOB43_000699"
     CDS             complement(11184..11876)
                     /locus_tag="NOB43_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI0981586.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11898..12872)
                     /locus_tag="NOB43_000700"
     CDS             complement(11898..12872)
                     /locus_tag="NOB43_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0981587.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13172..14044
                     /locus_tag="NOB43_000701"
     CDS             13172..14044
                     /locus_tag="NOB43_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0981588.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14502..16700)
                     /locus_tag="NOB43_000702"
     CDS             complement(14502..16700)
                     /locus_tag="NOB43_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0981589.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16932..17924
                     /locus_tag="NOB43_000703"
     CDS             16932..17924
                     /locus_tag="NOB43_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0981590.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17984..19405
                     /locus_tag="NOB43_000704"
     CDS             17984..19405
                     /locus_tag="NOB43_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HCI0981591.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19398..20897
                     /locus_tag="NOB43_000705"
     CDS             19398..20897
                     /locus_tag="NOB43_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HCI0981592.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20936..22330
                     /gene="uxaC"
                     /locus_tag="NOB43_000706"
     CDS             20936..22330
                     /gene="uxaC"
                     /locus_tag="NOB43_000706"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCI0981593.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22489..23172
                     /locus_tag="NOB43_000707"
     CDS             22489..23172
                     /locus_tag="NOB43_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HCI0981594.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23174..24010
                     /locus_tag="NOB43_000708"
     CDS             23174..24010
                     /locus_tag="NOB43_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI0981595.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24021..25775
                     /locus_tag="NOB43_000709"
     CDS             24021..25775
                     /locus_tag="NOB43_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981596.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26051..26392)
                     /locus_tag="NOB43_000710"
     CDS             complement(26051..26392)
                     /locus_tag="NOB43_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0981597.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26460..28631)
                     /locus_tag="NOB43_000711"
     CDS             complement(26460..28631)
                     /locus_tag="NOB43_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI0981598.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28800..29699
                     /locus_tag="NOB43_000712"
     CDS             28800..29699
                     /locus_tag="NOB43_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0981599.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29770..30627)
                     /locus_tag="NOB43_000713"
     CDS             complement(29770..30627)
                     /locus_tag="NOB43_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0981600.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30612..33314)
                     /locus_tag="NOB43_000714"
     CDS             complement(30612..33314)
                     /locus_tag="NOB43_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HCI0981601.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33327..34616)
                     /locus_tag="NOB43_000715"
     CDS             complement(33327..34616)
                     /locus_tag="NOB43_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HCI0981602.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34766..35812
                     /locus_tag="NOB43_000716"
     CDS             34766..35812
                     /locus_tag="NOB43_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0981603.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35814..37967
                     /locus_tag="NOB43_000717"
     CDS             35814..37967
                     /locus_tag="NOB43_000717"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HCI0981604.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38440..39891)
                     /locus_tag="NOB43_000718"
     CDS             complement(38440..39891)
                     /locus_tag="NOB43_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0981605.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39888..41612)
                     /locus_tag="NOB43_000719"
     CDS             complement(39888..41612)
                     /locus_tag="NOB43_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0981606.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41605..42219)
                     /locus_tag="NOB43_000720"
     CDS             complement(41605..42219)
                     /locus_tag="NOB43_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI0981607.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42564..44021)
                     /locus_tag="NOB43_000721"
     CDS             complement(42564..44021)
                     /locus_tag="NOB43_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0981608.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44062..44982)
                     /locus_tag="NOB43_000722"
     CDS             complement(44062..44982)
                     /locus_tag="NOB43_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0981609.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44994..45941)
                     /locus_tag="NOB43_000723"
     CDS             complement(44994..45941)
                     /locus_tag="NOB43_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0981610.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46420..47139)
                     /locus_tag="NOB43_000724"
     CDS             complement(46420..47139)
                     /locus_tag="NOB43_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI0981611.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47188..48834)
                     /locus_tag="NOB43_000725"
     CDS             complement(47188..48834)
                     /locus_tag="NOB43_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0981612.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49013..49603
                     /locus_tag="NOB43_000726"
     CDS             49013..49603
                     /locus_tag="NOB43_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0981613.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49695..51200
                     /locus_tag="NOB43_000727"
     CDS             49695..51200
                     /locus_tag="NOB43_000727"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HCI0981614.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51284..52636)
                     /gene="celB"
                     /locus_tag="NOB43_000728"
     CDS             complement(51284..52636)
                     /gene="celB"
                     /locus_tag="NOB43_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI0981615.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52636..53154)
                     /locus_tag="NOB43_000729"
     CDS             complement(52636..53154)
                     /locus_tag="NOB43_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981616.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53170..53496)
                     /locus_tag="NOB43_000730"
     CDS             complement(53170..53496)
                     /locus_tag="NOB43_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HCI0981617.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53509..55488)
                     /locus_tag="NOB43_000731"
     CDS             complement(53509..55488)
                     /locus_tag="NOB43_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0981618.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55509..55823)
                     /locus_tag="NOB43_000732"
     CDS             complement(55509..55823)
                     /locus_tag="NOB43_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HCI0981619.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55991..56284
                     /locus_tag="NOB43_000733"
     CDS             55991..56284
                     /locus_tag="NOB43_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCI0981620.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56362..57474)
                     /locus_tag="NOB43_000734"
     CDS             complement(56362..57474)
                     /locus_tag="NOB43_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0981621.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57861..58040
                     /locus_tag="NOB43_000735"
     CDS             57861..58040
                     /locus_tag="NOB43_000735"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981622.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58234..58404
                     /locus_tag="NOB43_000736"
     CDS             58234..58404
                     /locus_tag="NOB43_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0981623.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58828..59775)
                     /locus_tag="NOB43_000737"
     CDS             complement(58828..59775)
                     /locus_tag="NOB43_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen binding domain-containing protein"
                     /protein_id="HCI0981624.1"
                     /translation="MQGAVFELQNREGETLQTGLTTGEDGKLAIDGLAPGAYQLVETQ
                     APTGYELDATPIEFEIERSQTAVVELTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQ
                     DANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAV
                     VELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDG
                     LAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTS
                     SGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17859 a        12243 c        10468 g        19259 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt tcgatttcgt
      181 ttttcgaaat ctttcagcaa ctcatttatc ataacttatc gtttgttatt tgtcaagaac
      241 ttttttgaag tttttttcga tagaatcaag cttcgcaagt ggttcttttt aacgacttag
      301 ttatcttatc acgtctaaaa acatgtgtca actctttttt ggaattttca taaaatgttt
      361 caatgaagcg cgacaacgtt gtttaatata tcattaaaaa aaataaaggt caagctaaaa
      421 tattatttaa gcttgacctt attataattt caacgattgt caaaagtatt gtttgcagct
      481 gtgttgccag tttctataga taaatcacag cttttgaaac ataagttttg tactgcttcg
      541 attcgcccga attcttttgc agttatttgg caatgagaaa agcagacatc ttctataggc
      601 ttttcaggaa atgctactaa atcaaaagct cgggaaggaa gtgagtaacc tggagaaagg
      661 catgcctgta cgtttttgat gtgtatgtct ttgactttcg tcatttgctt tgattcaggt
      721 atttcttcag ccactgcttg ccaactttct ggcatttgag caaggtcatt gctatttttt
      781 ctattgtatt cattatgcca gtccattatc caagaaaaag gaaattgtac atcaatcata
      841 ttcagatttt ctaccctgat attttcgatc actccccctc tttcttttga agatttcatt
      901 cgaataccac agtctgactg aaaaaaatcg atatcgtgaa tatatacgtc actaactcca
      961 gcactaactt cgctaccaat agttacaccg tatcctgaac ggattttaca tctagcaacc
     1021 tcgattcttg atgattttcg attgactctt gcaccattgc catctctgcc agacttaata
     1081 gcaatacaat catcaccaca ggccaaatca cattcataga cacgcacatt tgttgaagaa
     1141 tcaatatcaa tcccatctgt acttggtcca tcattgttgc ggatgattac tttttctact
     1201 aatacatcgt tagaataagt gatttgcaag ttccaaaaac ctgatttctg aaaaatcaaa
     1261 tcacgaacaa caacatgttc tgcatgatac agtaaacaag cgcgtggacg tttaatagca
     1321 taatccgcaa tccaacgaag tcccttttga tcgtattcag ctcttgtccc gcttttttga
     1381 tcttttcccc aatacagctc ccaccaatgg tctccttgac cgtcgattat tccttttcct
     1441 tctataagaa tatctttcgc cgagagaaca ttcaaaatcg ctgctggcca tttcatttct
     1501 acgccggcta ctcgtgtatc gatttctgga aatgcttcga tatctgttct ccccttgagg
     1561 actgcacctt cttcaaagat aagatgactc ttatctttta aaaaaagggc tccgactaaa
     1621 taaatgcctt ttggaataaa tacaggtaag tgttctttcg caccttgatc gattgctttt
     1681 tgcagtatta ttgtatcatc ttgttgagtg tcgtttgttt taaagttcaa agcattgata
     1741 atcccttttt ttgtccgcaa tacgtttctc cctatctttc attgattttt ttcaattctt
     1801 caccaataaa tacagttttt gaacgattca gtgggtaacc tactagcaaa atgattgcgg
     1861 atacaaataa gcagaatgct ggtaacaagt ttgccatcgt ataaatcctt tcttgtacta
     1921 aaactgattg gatggctcca cctgttgtag acgattggta accaatgagt gccagcataa
     1981 atccgcctac cgctcctgca catgcttgtc ctacttttct cgcaaaagaa tttactccat
     2041 atactgttcc atcttctctt aagcctgtct tatattgatg ataatcaatc acgtcagtaa
     2101 tgaatgccca gaccatcaaa ttgaataaac cagatcctaa agtagcgata aataaaagaa
     2161 tcagatatac ccatgcattt gttatatgaa ggaaatacat cagcaagtac atacatgaag
     2221 aagcaagtaa cgcaaatacg cttgcttcct ttttaccaaa taattttgtc agctttgtag
     2281 caaatggtgc taaaactact actgttccgt aagtaaataa aagagcaaca gacattgctt
     2341 gtttattatg gaagtaatca ttgaataaat aagtcatatt cgtcccagct aaaatctgat
     2401 tgatcacaat gaaaatgtca acaatgacta aaataatcag tgctcgatta gctaacaaac
     2461 cttttaccaa ctgagaagca gatacttttt cgtttttgac aactcttact ctttcagtag
     2521 tcaatttaca agttaacata tatgcgacaa atgctattgc agcacatccg attgaaatcc
     2581 aaaagaaatg attccctgaa acgacttgtt gtccactctt gttatgggta tacattaaaa
     2641 tcggaatgaa gaatcctgta gttgatccgc caatcgcaga accaatgctt cggaacgtgg
     2701 acaacgaggt gcggtcatta ggatttgagc taattgctgc tgccattgct ccatacggga
     2761 tattgattgt tgagagaaaa atcccataaa caatgtatga aacaaaaata taagcaatct
     2821 tcaccgtcat tggaagatgt tggacgaatg gcaaaaacaa aatgacagtc actaagcaaa
     2881 atggatactt catttttctg atccaaggaa taaatcggcc agtttctgtt aactctgaga
     2941 catcacataa tcttccaacc atcacatcag caaacgcatc caaaattctc gaaatcaaga
     3001 ataacgtacc tacgattgcc cctgaaacgc caagaacatt cgtataataa atcatcaaga
     3061 aactattgac taaacctaaa ataaaacagt tacctagatc accgaacatg tagcctatct
     3121 tatcggaaat cccaaattcc tttttttctt tttttattgt atttgctgta acagcatttt
     3181 gtgaaagcat ttgaattcct cctacctctt ctagtaaacg ttttcaaaat tataactctt
     3241 tttttcttgt ttttatattc acaatgttgg ctttttattg cattatcttg acagataaaa
     3301 aacaaaaaat aatctaaaaa cattgatgca taagattgat aacttttttt acataacaat
     3361 atatacaaac aaaaaaattc actaactagt gaaaataagt tagtgaacct catttattaa
     3421 agaattaaat tacagatgat cttttccatc atacttgaaa aactcaaaat cagcataact
     3481 tcctcttttt ttatttagat catgcactgc tatcccgata aaatttccag taaaccctcc
     3541 tgagagtata cacatgtttt tttgcggacc tactttcttc cattcttcag ttgatacgtc
     3601 tttcaaatga aactgtgctg tctctttctt tacagtgact ttcaaaaaag tcttcttttc
     3661 tgtgagtgga atcgtccaat cttctatttg tgctactccg ttttctgatt ctatcatacg
     3721 taggcatttt cccttgtcct cattccaagt aacataacaa taaatataat tggattcatt
     3781 taagtacagt accagtccag ccatctgatt aaaattatta ggcatgtatt caaatgctgt
     3841 ctccgcatca aaagtaaaat ccgtttgccg aatagctaac aaatgatgtt cgaaggtaga
     3901 ttgaagagat tcaccggaaa tcagacgtaa aaaacctggt ctacattttg tatcacacca
     3961 atcagcattt ggcaaaatgc gtctggcatt ccagttcttc tttagctctc cttcaaatgt
     4021 atccataaac tgatgatctt tttcttgttg tacctcttca tttgtctcaa tcattatttc
     4081 ttccatcgga gttgtctggc tatctttaag tcttaaccaa tcgtcggacg tccaatacac
     4141 ttcttgaata gcggtttctc ttcccaaaat agccgcaccg tttaatggtc tggtacaaag
     4201 atatgtcatg taccatcttc ctgacggggt ttgtactaag ctcccatgtc ctgtacattg
     4261 caatgtagaa gcaggtttgt cactagctgt cagcatagga aaaccaggat caagctcgta
     4321 aggaccagta atattctttg ctcggcaaac tgtaactgaa tgtcctcttc ctgtaccgcc
     4381 ttctgccgtc atcaaataat aatacccgtt acgaaaatac aaatgtggtg cctccgtttt
     4441 cgctaattct gtacctgcaa atattttata gatgggacca tcaagcttct tcttctctgc
     4501 atcatattct tgtaatacga taccgctgga tttattcggt gtgtccagac gataatccca
     4561 tagttcattg acaagccatt tttttcccgt ttcaagatca tggaacaaag aaggatcaaa
     4621 gccgttacta tttaaataaa ttggttcgga ccaaggacct gtgatctcag atgcagtgat
     4681 caaataattg tggacatctt taaacggacg gcctgcactt ttgacatctg tgtaaacaag
     4741 ataaaacaat ccatcagcat aactgatctg tggcgcccat atacttccat ttgtaggatt
     4801 tccttgcaaa gatacttgag tggtcaaaat atccgttgta tgtgaccagt tgactaaatt
     4861 tttcgactca tatactcgga ttcctggaag ccattcaaaa gaggagacaa taatgtaata
     4921 ccgctctttc actcttaata tattaggatc tggattgaat cctcttaaaa taggattttt
     4981 cactttgata gtctgcatga ttcaggctcc ttttctcatt cttactcgat ataaactgaa
     5041 tgccccagct gcgaaataaa aaaatgcaaa aggaaacgca ataaactgag tgccaatcaa
     5101 caatatgaat cctgttataa aatacaaacc agtggcagtt gttaagtatt ttcctttagc
     5161 agtcaaaaac aatgctactg ctaaaaaagc aagtgaaata aacaacacaa cggcaaacag
     5221 accagtcatg tcctgtaata atccaaatgt attttctaaa gacaaagttg aatgatctac
     5281 agcaagcgac tgataacttt ttttaaactc tgacgcagac atattactta aagtaactgc
     5341 taacccgcca aagaaaatca aagatagact gccaccgacc attcctagca atagttccca
     5401 ttttcttttc atttctgaac cccctgcttt tctaaatgta tccattcagg tcttttgatc
     5461 gatgtttcat aattgttatt acgttcagag aatttgacag tctgttcatt tttcttgtca
     5521 tcccaattat cccaaccagt tgggtgaaca tgcccaccta tcttacacgc ttcaaataag
     5581 acatttgcat acggacgcca cggtcttcct aaatagacgt ttctagtatc aggttctgca
     5641 gtcaaggtac agctttcaaa acgataccct gttttttgat ttttcggcgt agatgctgct
     5701 gtgatgtatc caggattttt actggctaag ctatggatat gacactgatg aaaaacggca
     5761 tctgccccac caaatatgaa atccaccgtt ccttcaatcc agcaatattc ataggtctga
     5821 cgacaatact caggattggc agaagccggt gtacaaaaag gagtaccatc tttttgcaaa
     5881 tcaggcaacg gacccgtgca taaggtatcc tgataaccag atagtcgaca gttttttaaa
     5941 gatacgcgat ctcctgaatt gaataaagca acagcctgtc ctaccttttc tcctggacct
     6001 gctgtatttt cgatgtgaag attttctaat acgacattcg atccttctaa gaaaaaagta
     6061 gcacttcgga aagtccctaa ctggctaccg tcaagatact cctgttttgc aaaacgatta
     6121 ccggagataa ctactgttcc tgctcccaca agtttaaaat tggataatct gctttctata
     6181 tattcatcat atcttccttc ttttactatc aagacctttg gatggctatc cggcaggcct
     6241 gccaaataat cgattccttc ttggatagtt tcaaaatccg tcggggtatc tatagcattc
     6301 tttccaatta tcagtttgtc tttcatcctc ataaatgctc ccttatgaat tgtttccaaa
     6361 tatttctcat ttcttgtgtt tccatatgac cgcctgttaa agaaaaagaa gaaaagtttt
     6421 ctggactacc cattgattga tactttttgt ccagcccttt tctcagcttc agtacgcctt
     6481 cgtccaagca catcgtatcg ttttttccaa ctaagctaag acgagggcgc ggagcgattt
     6541 tttcttggat tgctaacgtt gtataagctg tcaatagatt tggcacatag taataaaacc
     6601 catgatgatc taggcggcga tgtagcaaaa gtatttcgat gtccacctgt gccgctagat
     6661 caatacaaac tttgacacga gaatccaatg ctgtcaccca ccagcttaat aagcctccca
     6721 tagaaagacc aatcgttgcg agccgttgag tatctgtgtc ttcccttgtc tccaaataat
     6781 cgatcaagct gatcacatca taaatacgca ttccccataa cgtttttcct gttaataaaa
     6841 attgtttgaa caactcgctt tcagaaatac ctccgcgttc ttcaaatccc caagcatcaa
     6901 tcgaccaaac agcatatccc attcctgtca gtacttctgc aaaagatgga gaagctaagt
     6961 aaggagcacc atggatcaat tcacttttcc cgactgaaaa atctccgccg tgagaatgca
     7021 ggtaaaggac cggcggaaac ggtccttctt tttctggata agcatagagg gctggtactg
     7081 tttccaattc atttaagtac aattgatagt attcaagcat aaaaccgttt tgtttttctc
     7141 ggtataatcg ttttccacta ggggtatgtc tgctagatgg agcacctaaa aaatcattca
     7201 actgcataag caaagttttt acgaacaacc agttcatcca tattttctga ttgatttgat
     7261 tggaatttct caatactgat ttctttagta ttttctaata gaaatgctgg tccctcgtga
     7321 ttttcaatcg acatctggtt aaaggaaacc ttacccgcaa agccaatata aaatccttgt
     7381 ctgctcattt cctctattcc tgtcatcata gcaggaacac cgggaactgc atcttgggcc
     7441 atcgagacat cgatattgtc aaatgtgatt tcttgtatga attgttccgc taatccataa
     7501 ataaaacctg cagaagcatg gacattcctt gccgtgatat tcgaaaaatg gatccttctg
     7561 aatgctggtg tccgttcatc tatcggataa gccttttttc ccatacatac ggttctttcc
     7621 ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca ttatccatga
     7681 ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta gatttcaatc
     7741 gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta cgaatactac
     7801 cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg caatttgtga
     7861 tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc ttgattgcaa
     7921 tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg catgattctg
     7981 gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag ttatcaaacg
     8041 ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc aatttaatat
     8101 ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga ggataagcga
     8161 gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca tctaatgtac
     8221 cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa gcataaactt
     8281 ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga tcgtcagaga
     8341 atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa aataaagctc
     8401 ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt gctgcagcat
     8461 caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca aatgtcaaaa
     8521 tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg caccaacgcc
     8581 tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac catctcgctg
     8641 atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc agccttcttt
     8701 tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt gtggaagcca
     8761 ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa caaacatact
     8821 actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta cttgatacca
     8881 tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt ctagaatttc
     8941 tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg ctgcagccat
     9001 caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt ttggatcagc
     9061 ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt ttggatcgaa
     9121 tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt tttcttcact
     9181 aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat ccaaccaaat
     9241 ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg gatggtttgc
     9301 caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg tttctttgta
     9361 caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt caacgctgta
     9421 gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta tgaaatcaaa
     9481 ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta cgacgccata
     9541 gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg ttctttccat
     9601 gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt taaaaattaa
     9661 aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat tactgtgccg
     9721 ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt gctttccagt
     9781 cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat tgcaccgtag
     9841 catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt gaatccaatg
     9901 gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga ttagagaatt
     9961 ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga gagcttgata
    10021 acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa ccatcatcat
    10081 tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca tcttcttcta
    10141 aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt acttgagatt
    10201 tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga taaccgccgc
    10261 cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga ataccttgac
    10321 ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt cttccttgtg
    10381 caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc aaatagccat
    10441 tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta tcaaattctg
    10501 gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa taagaagtga
    10561 aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa ccaactgtgt
    10621 cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact tcataaagct
    10681 catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt cgaatgacta
    10741 agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg tcgatactcg
    10801 cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt aaatattctg
    10861 atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt ttcaacatcg
    10921 caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt gttaatcttt
    10981 cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt ttttcttcga
    11041 tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt aaccaagtga
    11101 ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg ccgcatgcgg
    11161 caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct tttttcataa
    11221 attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc tgtatatgag
    11281 ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc ggaaaagaag
    11341 agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat cagataaatc
    11401 cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc gaataaaaat
    11461 gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat tgggaaaata
    11521 tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct aagataccaa
    11581 ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata tatccagctc
    11641 atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt cgtcaaagga
    11701 aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata cgatgcagga
    11761 ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa attcaaataa
    11821 accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg cagcatatct
    11881 ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc aatcttatta
    11941 gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc tgtactgaaa
    12001 cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat ttctgcaacg
    12061 cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc taatgtctga
    12121 ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa tgtaacatgc
    12181 catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa ctgtgtatcg
    12241 actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt ccagatcact
    12301 tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat tttttcaaat
    12361 cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa tacataagta
    12421 atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt ttgaatcccg
    12481 tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat tggcatcgga
    12541 aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa tgtaaagaat
    12601 gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact tcccattatt
    12661 cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg aagataccta
    12721 aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt attcgttttg
    12781 attcctgcaa ttattttttt tcgtcttctg agcttttctt cttttttcga tagcgtcagt
    12841 tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt gtgaatgttt
    12901 gctgcttatg acttcatgat agataactat ctgaattacg tatataatca tttttaccgt
    12961 aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa agtgtatttt
    13021 ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca cttagcatag
    13081 gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga aacagaaaca
    13141 tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta taggagaaag
    13201 aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct gtatcgttcc
    13261 ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg cgaaaaagtt
    13321 tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt ctacgccgac
    13381 catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga tcgtcagtat
    13441 gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg gtcgaggttt
    13501 cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc caacgttctt
    13561 agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc ctgtggctgt
    13621 taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg atagtttgga
    13681 agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa ttatgctgcc
    13741 attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt actggaacac
    13801 ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac agattctttt
    13861 acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg ttgatgtgat
    13921 tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc ctatgctgat
    13981 tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt ctgtcaaagg
    14041 gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct tcaagaaata
    14101 agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt atttttcgaa
    14161 gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca gccttgagcg
    14221 atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata agaagcgatt
    14281 ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag cctgtctctt
    14341 gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt tctttttgcg
    14401 tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt ctaacttctt
    14461 ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata tttttttcga
    14521 tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt ttgcggattt
    14581 cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt caaccatttt
    14641 tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc tgtttccttt
    14701 ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat cacatctaaa
    14761 gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga caaattttta
    14821 aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa ttgttctaaa
    14881 acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata aatttgtttc
    14941 atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac gagttcattg
    15001 atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc aaacaatgca
    15061 tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat ggcttcaaac
    15121 aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc agcaggaacg
    15181 atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata cagggcttct
    15241 tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt actgatgcct
    15301 atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg gcaatactcc
    15361 atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt ggcttgcatt
    15421 tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc cgtgatcatg
    15481 ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc taacagatcg
    15541 atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa ttgctgcaac
    15601 cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac aaatagcgtt
    15661 tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc tcctatgatc
    15721 cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt tgatttaaga
    15781 ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa taagtaggaa
    15841 agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat tctcagattg
    15901 cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca attattataa
    15961 tctgatttca gtactatata cgttttatct ttttctctta tcactttcag ctgattgtaa
    16021 tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt ctgagtagta
    16081 aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc accaacaact
    16141 tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc tttttcaaac
    16201 attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa taaattattt
    16261 ttgttattta tgtacttctg ttgatacttt tcaatttcct cttcggtcag ttgactcaac
    16321 gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt attatcatcc
    16381 ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt ggagtaatct
    16441 gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc atacgtagaa
    16501 aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg cctgagcaaa
    16561 ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg gtaaatgaat
    16621 aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa tattttataa
    16681 aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag gctttcattt
    16741 ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa gaatagcata
    16801 attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat caaagatcta
    16861 ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga aaaagtaagg
    16921 aaaatgatgg aatggtaacg atcaaagatg tcgctaaagc agctggcgtt tctcatacga
    16981 cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa caaaaaatac
    17041 gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt ttagtgaatc
    17101 aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact tcatcaaatt
    17161 tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac agtttatctg
    17221 ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac gatggactga
    17281 tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa gaaaaagaat
    17341 ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac gtcactgccg
    17401 atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga catacgaaga
    17461 tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa aaaggggtat
    17521 tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta acaggagatt
    17581 acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct gacctgccta
    17641 ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct gtacatttag
    17701 ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct ccagtcgtct
    17761 cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg tgtcaagaag
    17821 gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct aaaattgagc
    17881 tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca agtaatttta
    17941 tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa aactgacaaa
    18001 agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg aaggcaattt
    18061 tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat tgtttaaagg
    18121 taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga accagcaaga
    18181 taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg atacttccga
    18241 gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg cttatctatc
    18301 tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg caggaatcca
    18361 attcgtggag actgataatt taacagatac tcccccacag agcctcccgg gcaaactgac
    18421 agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca ttccttgcga
    18481 actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg cagaaaaatg
    18541 ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct gttgtagttt
    18601 agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca atcaacggca
    18661 taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg tgatcgaagg
    18721 gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg tcatcatcac
    18781 agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac cgcatacagc
    18841 gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa tgaaagatcc
    18901 tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta tgctttcttt
    18961 acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct tgaatccttt
    19021 tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca gcacccgtct
    19081 gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt taatcactgt
    19141 ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac atgatgatga
    19201 aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta ttcctcgatt
    19261 attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg tgacagatac
    19321 agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat tacaagaaat
    19381 gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta aatcgacgag
    19441 acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg attgatcagc
    19501 aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg ggtgatttga
    19561 aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg acagacgtaa
    19621 ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt gaattggatt
    19681 atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga acatttcaag
    19741 gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta gtacctaccg
    19801 ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa aaacatccag
    19861 atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt tcgcagcttg
    19921 gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat cccaatgccg
    19981 gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa ttcaaaaaaa
    20041 ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat gtttacgatg
    20101 agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa aatgaccagc
    20161 gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt tctgatggtc
    20221 tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg attgctcaag
    20281 gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa gtattgatgg
    20341 cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat gacttcaaac
    20401 agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt aataaagcag
    20461 gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca ggaagctctc
    20521 ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt agtttattgc
    20581 aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat tgccagttgg
    20641 tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg gtcaaggtat
    20701 ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat gcaggcgtct
    20761 tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc atcgctgtag
    20821 ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc atttttaaaa
    20881 acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa gatttatgtt
    20941 tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc attcctacgc
    21001 aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa tttacgaaaa
    21061 caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca aatggcgctt
    21121 gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg attttgaaaa
    21181 atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt acagttggtc
    21241 acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag aaaatgcaga
    21301 gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc gtcgggaaat
    21361 cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag acgacttgca
    21421 ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt cattccgtcc
    21481 agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac tactggaaga
    21541 agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag ggcagcggat
    21601 agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca tcttacgcta
    21661 taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag ctaacaaact
    21721 attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt tgacccactt
    21781 ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta actgtaatac
    21841 acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg atctttcttt
    21901 gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt tgccaaagac
    21961 gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga tgggctgttt
    22021 ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca acgatactcg
    22081 agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg ggaattttgt
    22141 cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat atttccgtcg
    22201 tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg aagatgaaca
    22261 acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt actttggctt
    22321 ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt gaaataacgg
    22381 aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt cttcttctct
    22441 tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat gcctactatc
    22501 catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc cgagacaggt
    22561 tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa ccaagcaaag
    22621 aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct agcttcacag
    22681 tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa aatccaagaa
    22741 gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt ttttgaatgc
    22801 gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg agattactta
    22861 gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat gcgtgcattt
    22921 gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga attgttccag
    22981 accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga tacttgtaaa
    23041 aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc tgataaagtt
    23101 gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa ttatttacaa
    23161 aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt tagatgttcg
    23221 aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata tccaatttgc
    23281 accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg ggagtgctgc
    23341 ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag gatgctatat
    23401 caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt tcaaacagca
    23461 aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg gtagtgtctc
    23521 tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca gaaattctat
    23581 cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg aagcagggat
    23641 caatcatcca atctataact atcagttagc taaacgttta atcgatgaag tagcttcacc
    23701 aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc atgctgatca
    23761 ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag cgcttcatct
    23821 caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca agggctgttt
    23881 agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt acgccactct
    23941 tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt ttatttacca
    24001 agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa aaatatcatg
    24061 caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt tttgccatgt
    24121 caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc gctattgcca
    24181 atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt tatttcaacg
    24241 cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt catgtaaaat
    24301 accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt atcaagaaaa
    24361 tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc cagtcaaaga
    24421 tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc agcggattaa
    24481 atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt cctgttgttt
    24541 tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt ttccgtaaaa
    24601 ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct gcaaaagtga
    24661 tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa cacgaaacaa
    24721 ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta gatatcctgc
    24781 aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg atttgtttga
    24841 ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc gtgatgtatc
    24901 agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg attcctacga
    24961 tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct ggcgatgtag
    25021 aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt tttgaggatg
    25081 tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct ctagaggtga
    25141 aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct acactcctta
    25201 acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat gatcagcctt
    25261 tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct caaaccactt
    25321 tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac gtatcaaaag
    25381 aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac cagcttcctg
    25441 atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc caaaagcaac
    25501 gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta gatgaagcaa
    25561 cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat tacctgacag
    25621 aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag gcagataaaa
    25681 tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa ctgttagctc
    25741 aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct atgacaagac
    25801 ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc tcggtcacaa
    25861 gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg taactcagag
    25921 ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc tatcggcaat
    25981 aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc tgttgtttca
    26041 taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata cggttcaagt
    26101 cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt acttcttctg
    26161 attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg aactcttgtc
    26221 cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg aacagtttgt
    26281 gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg aattctggta
    26341 attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac atgttatgcc
    26401 ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt tcaaaggggc
    26461 tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc ctgaacgcct
    26521 tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc atattgattc
    26581 aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc aacttgatct
    26641 gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc tgtttttgaa
    26701 gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac atttccactt
    26761 gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt cgaaatcact
    26821 acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc gaaattagtt
    26881 tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc agccgctgtt
    26941 ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc ctttgatatg
    27001 acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga atcaacgatt
    27061 ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact gtaagcaccc
    27121 gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc ataatactta
    27181 tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt ttgtaaaccg
    27241 atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc ttgatacatc
    27301 ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact ttgcggttcg
    27361 tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata tacgcttaat
    27421 ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa tcctctaaag
    27481 acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg atctaaagct
    27541 actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa tgcactgttt
    27601 tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata gattttatag
    27661 cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc atcgatcact
    27721 gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt gtcattaaga
    27781 tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat ttttccgttt
    27841 tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg gtgatcgatc
    27901 ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc agacagcgta
    27961 acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc ccataccccg
    28021 ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct gtacttcttt
    28081 tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg gtctaatgtc
    28141 agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc tgatgttccg
    28201 ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa cccgtgatgc
    28261 tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg agaaatcgcg
    28321 tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc gtttttctta
    28381 tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt tgcttgtttt
    28441 gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat cagcaaaatc
    28501 aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa ttgtccgaga
    28561 tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc taaaatgctt
    28621 tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt ttaccatagt
    28681 gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac gttagtgcaa
    28741 gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat gttttaaaaa
    28801 tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc acgatcactt
    28861 tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa tggttagttc
    28921 ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat caacaacctg
    28981 ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc gaagaaacag
    29041 attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt ttatatgaag
    29101 atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca aatgaaccga
    29161 cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa cagcaacgac
    29221 cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt gcaaaaaatc
    29281 catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat cggagatatc
    29341 aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa attggacgag
    29401 atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc gccttgacac
    29461 atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt ttggaaaccg
    29521 gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc gttggagacc
    29581 ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa ctgcacatga
    29641 tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta tgggaataga
    29701 aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct ttttgtgtaa
    29761 tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga taatcccact
    29821 ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt ccatataacc
    29881 acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct gattcattac
    29941 cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga tcagtgcttg
    30001 agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat cttgcccttt
    30061 gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac aatctttatg
    30121 ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa tatgtcccat
    30181 ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg caccgattcc
    30241 tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt gcttcaattc
    30301 cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt agcgttcctt
    30361 gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca aaacgtatcc
    30421 gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc cgattccctt
    30481 caattcataa cgatcaaaaa attcaaatac ctgatccaat gtttcttctg gtgttgtggt
    30541 agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca caaattttgt
    30601 tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat tgtccgaatc
    30661 tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag cagattcaat
    30721 atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact agacatattg
    30781 aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt aattgcaaac
    30841 gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc atgatgtttg
    30901 atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt agagaatttt
    30961 tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag acactgtgct
    31021 tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag tagcgtcact
    31081 gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc gactgttaca
    31141 ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt cgtggggttt
    31201 tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact atctgcttcg
    31261 tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc tttcatctga
    31321 ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt catgattgtt
    31381 tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg aaattccaca
    31441 accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc catttcctgt
    31501 agaatactta tttttgctat ttccggtgta tctactaata cttttacttc agagttttct
    31561 ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata ctcatttcct
    31621 atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt tttgcgatct
    31681 tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt ttcgatgatt
    31741 cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc ttctacaagc
    31801 gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac tttgatcatt
    31861 cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa ttggacagtt
    31921 tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg atacttacgt
    31981 ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc gaatcttttt
    32041 ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc agtatttaca
    32101 atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc ggtcagctgt
    32161 tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa acgaggtatc
    32221 atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg atgattttgc
    32281 attaatgtct tccaagcata atctaattga tcatggggat agtttccact aacttcataa
    32341 gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt ggtattccat
    32401 tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc atccgtttct
    32461 tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt ttgaactgct
    32521 tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag ttcatttgcg
    32581 agatggattg cttttgatat atctttttgt accggttgat gatcaacacc attcatcatc
    32641 aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt ccaaaaggca
    32701 agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt ggcaaatagc
    32761 agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta ttgggaagaa
    32821 tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc acggccaaac
    32881 gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat atttccaaat
    32941 gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc ttccatgcca
    33001 atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg caagatataa
    33061 aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg tcttttttct
    33121 ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg aaaactgttg
    33181 aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat cagtcgcatg
    33241 tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga aatgatatat
    33301 actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa gtaatccatg
    33361 actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata attttcagga
    33421 ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc tacaagtaaa
    33481 ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat agctaatgca
    33541 atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc gtactttcct
    33601 tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag ataatcttcc
    33661 tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac attactgtca
    33721 tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt ttgccctttt
    33781 tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt caatttctgt
    33841 gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc cacataacct
    33901 aacacgacca ccgcaaacat attggatggt accagatatc cataacggca agtatcatcg
    33961 ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc tcgcccgtca
    34021 ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg agagtgttca
    34081 tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat aaaagattga
    34141 ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg tattgggtag
    34201 cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt tgtatgatct
    34261 gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg atcgatattg
    34321 atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc ctcatcttct
    34381 tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca catcgctgga
    34441 atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt tgtcaacaga
    34501 gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc cccacatttt
    34561 tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata agccactaat
    34621 aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc caattatgtc
    34681 tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat tatttgaata
    34741 tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa tatttaatga
    34801 tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac caactgaaaa
    34861 agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat tgactgaatt
    34921 agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta aatccgcttc
    34981 tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc ttcttccata
    35041 tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga tgcaagataa
    35101 acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag caaaagagct
    35161 aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac atcttgactt
    35221 actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa aaatctatga
    35281 gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg ctgcctctta
    35341 tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga ctcatccaca
    35401 atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg gtttgacttt
    35461 ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt atatcactaa
    35521 gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga ccatgaatct
    35581 cttgagacag catggttatc atatccctga agatttttca attatcggat ttgatgatat
    35641 ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt ttgaacagtt
    35701 aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc gaccatccga
    35761 tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat aaaatgaata
    35821 tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct aatgggaact
    35881 gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa actacggatc
    35941 aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac cgtcttaccc
    36001 atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg atcaatggaa
    36061 aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa gaaagtatat
    36121 tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct acattgatac
    36181 ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc ggtttacttt
    36241 tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg gaaggaaaaa
    36301 tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata ttgagatttg
    36361 aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac tcgatcccgt
    36421 tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt atcagctcgg
    36481 aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact taccttgctc
    36541 acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac catgatcaac
    36601 aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca caaacatttt
    36661 atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga tctataaaac
    36721 ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt tatcctcttt
    36781 attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg aacagctata
    36841 gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt atgcctggga
    36901 cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga gacttgatgc
    36961 ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat ccaaattatg
    37021 gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac taccacgaat
    37081 cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa gttgccaagg
    37141 tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac tatcaaaata
    37201 tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag ttcagagaac
    37261 cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg caaagcagct
    37321 ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt gagagatata
    37381 aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga ggatatggtt
    37441 ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta gctatttcaa
    37501 accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct gaaatggcac
    37561 agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg ggttaccctg
    37621 gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg ggattttatc
    37681 ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac aaggctgttt
    37741 tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg ccgcagcaac
    37801 aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat tttacccatc
    37861 aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct caccctaaga
    37921 aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa gaggttgtga
    37981 aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagatcc tcatattttt
    38041 cgtttggttg gtcttattac cgcagatgca agcttttgaa caccgtttat tgagaggttg
    38101 tgaaatcagc gttctgacct gagtattaga gagacaaatg gcaaaatagt tcctcatatt
    38161 ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta gtggagaggt
    38221 cgtgaaaaag ctgtttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
    38281 tttttgcata aatttggctt aataccgaga aactggcttt tgaactccgt ttatcgagag
    38341 gtcatgaaaa agctgccttg cctcaagtaa taagaacagc ccaaaattag atttctagac
    38401 aattttttat aagttatttc attacattgg ctttttcttt tatgattctc cactgttttc
    38461 tcggtactct ttaggggatc tgccgacgat tttcttgaat aatttagaga aatacgtggt
    38521 gttgttgtag ccaatctcac ttgctatctc attgatgttt tgattactgt gcaaaagcag
    38581 ttgtttcgct ttttccatac gtaaatggtt caaataagct gaaaaacttt ttttcgtttc
    38641 ttttttgaac agctgtccta gatacatgac atttaaatgc aggttttctg acacttcttt
    38701 gagtgtaagt ggttcttgat aatgctggtg caggattacg attacttttt ccacattgtc
    38761 actgtacttt ttctgtctct gatgcttttt gatgaatgac agaagtagct gctgaagttc
    38821 ttgcaccgtt tttgcctgat ggattttttc gattccttgt aaatattcct catcttccag
    38881 atcaatcaat tcccgttgaa tctccataaa cagtaaaaaa ctggaatatc gtatatcttc
    38941 cggcatcatg gctgctaact gaaactgttc aaaaaaatca gtgatcattt tttgagcgac
    39001 ttccaattgt ttattttgca gcacgcgtct gaaacttgaa aaatcgatgg tttgatcttt
    39061 tgtttctgct tgtactgcgt aaaaaacatg ctcgtcttta tctccataaa attgatgcaa
    39121 ctgtagattg tctttcgctt gttggaatgt ttcagggatt ttgtccaaag aatctgtctc
    39181 ttccccgata ctgatcagcc attcctgatc aggaaagttt tcttgaacaa aacaacagaa
    39241 gccatcaact tcatctgcct ccaacaacaa cgtgatcaat acacggtctc cgtaatttcg
    39301 ttgatagtaa aagatttgtt gccgttcttg caaccatcta ttgataagag tatcatgagt
    39361 tcttgccagt tgaatcaata ctatcctatg ctgcttctca cttatttgtc ctattatttc
    39421 ttcttcactt atttcatcca attcttcatt caaccattga ctgaataaca gttcttgata
    39481 gatttcttgt tgattttttt gttcattttg ctgatctaac cgtgttttga ttttcttgag
    39541 gctttcaacc aattcgaact tattcacggg tttcatcaaa taattcacgg cgcctaattg
    39601 catacctcct ttcaaataat cgaattcttg gtatcctgat aaaatcataa attcaaaatt
    39661 atgacgttct ttttgagccg cttcaataaa ttccagtcca tttatttctg gcattgtcac
    39721 atccgttact actaaatcaa tctgtcgctg ttcaagtaca gctagtcctt ctttggcatt
    39781 ctctgctgtt gctactattt gaaagcctaa actttgccaa tcaattatct tttttaaccc
    39841 attcaaaatc atgtattcat catctaccaa taacacttga tacacgctca tccctccttg
    39901 aatgtaatag aaacggtcag tccacctgtc tcattattct caagcgacat ataataactg
    39961 ctgccgaagc tggcacgtaa acgttcattc acgttttgca gaccgataga accgtgaagt
    40021 tccactttag gatgagacag tttttcttca atctgtttta gccgtttttc agtcatccct
    40081 tttccattat ctttgatgat gatccttacc cgtttgcctt cctgcaagac tttgacactt
    40141 agcgcattat cgaatcgagt aaaatcaata ccgtgtttaa aataattttc aactaatggc
    40201 tggatcacaa atttaggtac ttcgatcttt tccaaatcag gatcgatcat aaaatgatag
    40261 gctactcgat taggataacg catttgatac aaatagacat atttttcgca aaagtccagt
    40321 tcttctttta aagtgatcgt tttctcttga ttcgtattgt ttcgaagcaa agcggaaaac
    40381 gcatacacaa catctgctaa ttcttcactt ccttcgctga ttgcatacat tcggatatat
    40441 tctaatgtat tatataaaaa gtgtggattg atctgtgctt gaagcgcccg catatgtgcg
    40501 tcttgctgtt tgatttctaa tttgtagatg tcttctacaa actgattgat gctatccaac
    40561 atttcgttga taccgattga aagttccttc agttcatatt ccgtgtttgt tatgtcgatc
    40621 cgcgtctcta aattccctgc tgctgtttga tccatggcct gcatgacgat agatacttgc
    40681 tgtgaatatc gtttgaatgt tttataaaga aagataagca gtatattgtc taaaataatg
    40741 ataccaatga tcagcggggc aagatttttt cccgtttcga tttttacact ttttttatct
    40801 agtacagcta atatacgata atcatcagac agttcttggt gttgaacaaa attgtttttt
    40861 tccagatcgt caatcggcaa ttgtgaattt ttcttcagac tctctgtgat gatcatttct
    40921 tgtctttcaa acgtttcttt agctatttta ttatcatgga atgtgtatag tcgatttgtc
    40981 gttccagaaa tcatgtataa agagagtcca ttgaatgacg ttagattttc taaaatcata
    41041 tctagttctt tcttttgaaa accaataaaa atacttcctg actcagctcc tccttgtgtg
    41101 ataggcaact tgatataaaa ggcgtctagt aattttggtg tccccttttt tatttcccca
    41161 cctttgtttt ctctagaaga ttcataatac tccggtagtt gattcaacac gatatatatc
    41221 gcacttagtt cttcataatt tgcgtagaga tctttgattt gatttgggaa agaaactaat
    41281 tcatcggtac tgttttgctg ttcgtataca tacatcagat actgatctat gggttttgtt
    41341 aagtaggtcg tcacattttc gatcttttcg gaattcccta caagctggtt tttgatgatc
    41401 ctactcaagg ttgttttatc attcagcatt ctgcttgtgc tttgaacggc atcacttgtc
    41461 atgttttctg cctgtttttg attttgttcc caagtatgga tactaaaaat aacggtagca
    41521 gtcatcgtta caccgatcat gataaccgcg tatttccgca acagacgatt tagtaaggtt
    41581 ccttttgaaa atagaatccg aaacttattc ataactttcc aactgtttat ctaattcttc
    41641 acgccaatgt gttgtcatcg taccattcca aaccgtcaaa agaccaatga caccaaacag
    41701 gatcaatcct ttgaattgcc aagtcacgcc taaaattata ccgctaccaa taattatttt
    41761 tagaaaagac gaaaagctgg aaaaaaccga aataaaactt agctttagca gattaggaac
    41821 agagatcgta tattcactat ctaaaatcat actgtattga taagtagcaa ataggcagag
    41881 caaggcaaaa agtaaaataa aatcaatagc taaaaaaatg agccctttga tttgaacaga
    41941 taaatataaa ttgtaactca ataaagcagt accagataaa aataaactaa atagcagatt
    42001 gcctcttaaa aaatttcttt tatatatatt ccagcctctt tttattgtga tttctttata
    42061 ctcgaatccg tacaaataaa atagttcatt gactgttttc catgccgcac ctaatccaaa
    42121 gatgatcccg ccggcaaatg tatatatcca gaaatacaag gttagtttta taatgaccca
    42181 gatccggata aataactctt ccaaaacctt ccctaacata tcttctcctc caaacattaa
    42241 gtttatactt tctcattata caaaaaaagg ttgggcaatc agcaccttga cctgattatt
    42301 agagaaacaa acggaaaaat agttcctcat attttgtcgt tttgtgagcg aataccgagg
    42361 gttagctgat tgaacaccgt ttaccaagag tttgtgaaat agccgcttag tttcgagtag
    42421 taagaaaaat tttgtgaata tggctttcca catttttaca tatatttagc ttaataccga
    42481 gaaactggct tttgaacacc gtttattcgg aacaagaggt tgtgacacgt cttttgtcac
    42541 aacccctttg tctttattca ttattattct tgtcggaact catcatattg tttttgcatt
    42601 tctttcaata ccttatcata gccagccttg tccaaagcgt ctttcaattt cggtaatgtt
    42661 tcatctggat caacagtccc tgtattcaat ccatctaaat attgattcat gacattagaa
    42721 atattactta attctgtttt gacactgtca gtgttgaagc tgaatcctaa aatcggtgaa
    42781 gtttctgcat cagcaatcga ttgatcacgt ttggcaatca tgtcatccgt aatagactct
    42841 tgtgtatata gaatcttgtt gtttcctgta ttccaagcag acatatgtgt atttggctga
    42901 taaccatcta gcaatttgat tttatcatct gaaccatcga ctttttccca tgcttctccc
    42961 tcgatccccc aaacaagccc attcaataat tctggatcac tgttaagcag ccctagaagt
    43021 tctactgatt tttctttatt ttttgaagta tttgatacga caaaatttgc catttgtgct
    43081 tgagctgtag attttagtgg aacagtaatt gcttttgaga caagttcttg ttttgctgca
    43141 tttgtcaaaa ttgtatcgcc ataatcatac ggtccttgtg tttctccacg cattagccaa
    43201 gtatttcctt ctagtggata atccttattg ctcgttgcag cgtcacttgg aatgagtcct
    43261 tgtttgtacc agctatgcat tgtacgtaac agtccgatat acgtttcatt atcgtattgg
    43321 ttgatgattt tcgaatcatc tccatccaga tcaatagcaa atggtaacgt attccctaaa
    43381 ggataatcaa agttcccttg gactttgaag ccttgtccaa tggcaaaagc tgccgtgttt
    43441 ggttcttttt catggaattc cttcaagact ttttctgcat cagcgtaaga ttggattcca
    43501 tcaattgaaa gatcgtattt atctagtaaa gctttgttaa aagtaagtac ttgttgagca
    43561 aagacatttc cattgactgg gaaagcatat aattttccat tgaccagatt tcctttaata
    43621 tatgcttcat ctaaatcatt ataagctttt tcagcgtact taggcgctaa ttcagtcaaa
    43681 tcagcaaagg ctcctttttg ggcattggaa acatagttgt tcgcaaaggc gatatcataa
    43741 ttttccccgg aagaaatgat gacgttcatt ttcttttcgt aatcgcccca gccaatgtaa
    43801 ttgatattga cttttacacc gatctctttt tcgattcgtt tgtttgctac ttccatcaat
    43861 tgatcgaaat tatctggttt atctccgatt tgatacatct gcaaagtgtc cgaattgcta
    43921 gcttctgcct ggtctttaga accagaacct ccgcatgctg ctaatgttcc caacaacaac
    43981 gctgaaacac ctgtaaaggc tagtttcttc cataacttca tttttcttcc tcctaatttt
    44041 atgatttata tttttgtttc tttattcttt tactccgccg attgttagac ctttgacaaa
    44101 atgcttctgg aaaaatggat agctgatcgc aataggcaac gtcgagatga ctacgatcgc
    44161 cattctggca gattctcctg gaactgaggc taatccgcct gtcaattggc ttcctgctcc
    44221 tgaattttgt gtcagatatt gaatattact ttggattttc atcaaaagat actgtagtgg
    44281 aactagctta tcatcttgga tgtatagtaa agcattgaac cagtcattcc agtaacccaa
    44341 tgcggcaaat aaactgattg tcgcaatacc tggaacagct aacggtaaaa cgatctgaac
    44401 aaatattcgc agttcgctag ctccatcgat ccgtgccgat tcaataatcg aatcagagac
    44461 cgaacgttta aagaatgtgc gcatcacaat aatattgaag ggactgacag ccattggcaa
    44521 gatcaatgcc caaatcgtat cttttaactg aagaagattt gtcataacaa gataattggc
    44581 caccatccct ggtgagaaca acatcgtaat caaacaaaaa acggtaaaaa aacgacggaa
    44641 tggaaagttt gaccgtgaaa tcgcataagc atataaagaa gtagccgtgc tattgatcag
    44701 tgtacctaaa acagtaacaa gtacagtgac gaaaagcgct tggaaaattt tatcctgcat
    44761 ctggtcgaac aagtacgtat aaccaaatat actgaacttt tctggccaaa aactgtaccc
    44821 gtgagtcgac aatatggact catcggtaaa agagatggcg ataacaaata taaatggcaa
    44881 aatacaggaa atagcaaaga gtgcaatcat tatattagag aaaaaattag ccgtcttatt
    44941 gaaagagcgg acttggactc tctccacttt cttttttttc atttttttcc tccttagaat
    45001 aatgcagaat cgctatcaaa acgtcgggcg atcgtatttg tgatcatcaa caagacaaag
    45061 ccgacaactg attggtaaag tcctgcagca gccgtcatac caaaatctcc tgtggatgtc
    45121 aggccattgt agatatacgt atccaaaact tgagtcacat catataatgc accggaattc
    45181 ctaggaatgt tataaaacag gccaaaatca gctcggaaaa tgtttcctac ggctaaaatc
    45241 gttaaaatcg tcattagtgg aataagttgt ggtatcgtca catgtttgat ctgctgccat
    45301 ttgctagctc catcaaccat agcagcttca taataagtcg gatcgattcc cataacagat
    45361 gcaaagtaaa taatgctgtt ataaccaatc cctttccatg taccaatgaa caccaagata
    45421 aacggccaat atttcggttc attataccaa ttgacagctt ctcctccatg tccagtgatc
    45481 cactgattga atattccttt gtcaggactt aaaaaagcgt aaacaaagta actgataatg
    45541 acccaagata gaaaataagg tagtaaggac atcgtttgat aaactttaac gagtcgttta
    45601 tttctcaact cgctcataat gattgcaaat acgactgaga tcagcagatt caaaaggata
    45661 aatgctacat tatataaaat tgtattttta gtgatgagaa atgcttgatc cgaagaaaat
    45721 aaaaatttga aattttccca acccacccaa ggactttccc tcaagctagc caagaaccca
    45781 tctgctgaaa tatgaaaatt tttgaatgct acgacattcg ccattacagg tatgtaaaag
    45841 aaaaaaatca tccaaagcat acccggtaca gccatcagga caagtgcttt ataacgccat
    45901 agattcataa aaaaatgatt gaaccccttt cgttttttca tctaaaaacc cctttcgatt
    45961 cattcgcaac gtaattatag cgctttcaat aatgagaata aataaacaaa gtatagggaa
    46021 aatgaaacaa agtataggag aggttgtgaa atcagcgttt tggcctgagt attagagaaa
    46081 aaaacgggaa aatagttcct catattttgc cgttttttga gctaataccg agggtcagct
    46141 gattgaacac cgtttatcag aggttgtgaa ttcagcgttt tggcctgagt attagggaga
    46201 tcgtgtcctt actatctaac tctgagtcac aaggaacaat ggggactgta acaaaagtct
    46261 tgtcacagtc ccttattccg aacaaacggt gttccagaag tagcttctac ggaaataagc
    46321 cgaaatttca caaaaaagcc atccgaaagt cagacggaca agtctgcttt tcagatggcg
    46381 ctacaactac tctgcttatt cttttagcta tccattcaat tatttttctc tcacttgttc
    46441 tagctcttct ttggtcatgg gtcgatattg ccctttattc aaatctttag gcagccaaaa
    46501 ttttcccata cggattcttt ttaaatataa gacttctttt cctactgctt tgaccattcg
    46561 cttaacttgg tgaaactttc cttcatgcaa aatcagacgg ataattgaag tttctgtctc
    46621 ttgatctact tgatcaattt ggagttttgc cggcaatgtc tgctcatcgc catcaataat
    46681 cagtccttct gcaaataaac ggatatcttc ttctgtcatt ataccgctaa cctcagctag
    46741 atattctttc tccacatgtt ttttaggtga tagtaactga tgggcaaaca ccccgtcatt
    46801 cgttaaaatc aagaggccct ctgtgtcttt atctaatcgg ccgactggaa aaagatcttc
    46861 ccgataatcc tggtcttcca ataaatcgat tacggtttga tcatgattat cctgagtagc
    46921 agaaatgact cctgcaggtt tatgcaaaat gtagtaaaaa tctttttgat acgtaatgat
    46981 ttctcctaaa taagtaaccg catcttcgaa ttcatttact tgcgctttat cgcttttcac
    47041 cacttgtcca ttgacttcga tcgttccttt tttgattaat cctttgactt ctttgcggct
    47101 gccaagtccc atatctgcta aaaacttatc taaacgcatg cgtttccccc atttcaaaag
    47161 agcatcaatc tagctcttct gattcactta ttttattttt aatttatgtc gtaaacgcgc
    47221 tattcctggt cctagtagtc tttctgccaa gcggattttc aaagctaaat aaccatacac
    47281 taaagcccct atacctgcta ctacaagaat caacaataga gactggaatt tgctatcttc
    47341 gtttaaaaaa gcaccaaaaa tcatctttgt gatccacgaa gccaaaagca taatcaaggt
    47401 aagaataaag atcagcaatg tcctgcgcca gacaaaactt ggtttaaagc gggctacttc
    47461 atggattctc tttaagatca aggtacaaga cacagcaaat ccgatcattg tcgccaataa
    47521 agggccgtat acttcaaata aacgaatggc tgggtattga agaaggagtt tcactagaaa
    47581 cccaataacc aaataattaa ttgccgcctt gttttcaaac attccttgca gcatgttgga
    47641 aactagcata tatagtccta ggaagagtcc tacaaaactt gcttggatca gtacattact
    47701 tcctagagaa tccggtgtat aaaataatgt atttagcgga taggcaagta acataacacc
    47761 aaatgtcgcc ggaaacataa aaaatgaaaa caactgtaaa tttccgcttg tcaattttgc
    47821 cagacctact cgatctttca acgtaacagc ttctgtaatc aacggtaacc cagtagacgc
    47881 gatcgatgtt gccaatgcaa taactaccat cgtcaactta tctggattgg cactaaaaat
    47941 cgaaaaaaga tccagtaact gtgcattgga atactcggtg gatgcagaca tgatcttcat
    48001 aaaagtgaac tgatcgacta atttgaagat cgttacccct gaacccacaa taataaacgg
    48061 aatcgcttct ttaacggtat ctaacaacaa ttccttcgtt gcaatattta ttttgttttc
    48121 gctgtagtga ataaacgccg atgtatacgc ttgatgtttc ttcaaaaaat acaaaaggac
    48181 aagaatactt gctagcatac cgataaatgc cgcgaaagtt gattgcgtga ccgccgtcac
    48241 atagtcacca tccatgactt tcatgatgat gaatgtagcc aatagcatat aaaaaatacg
    48301 tgccacctgt tctacaatct gcgacagcgc ataaggcatc atttcttgat tgccttgcaa
    48361 ataccctcgt atcacactca tacaaggaaa aaccaataca gcgatactca aagaacgcat
    48421 cgttggaatc agttcttctc cgccaccaga agcatgagct agccaaggag aggcgatgta
    48481 catgaacaaa gcaaacaaca ggcctaaccc gcccatcatc tgtaatgcac ggataaataa
    48541 tcgtcgtgaa gtgccatatt cattcaatga attatagcgt gcagtttgtt ttgcaatcgc
    48601 agcaggtatt cctgctgtag agatcagtag aaacaatgca tatatattgt atcccatatt
    48661 gaataatcca ttggcagcct tagcattttc gcccatccaa gcataccagg gaatgatata
    48721 gacagcgcct agcaatcttg aaatgatatt actggcggtc atccaagcag agcctcgtgc
    48781 cattttttct tgcggtgtta attgatctaa tgctggtttt ctttgattat ccatcggtca
    48841 gattccaact ttctacaaaa cattactatc attttaattg gtaaaacaga aactggcaat
    48901 cgattttata taacttttat aagaacaatt gtttttttga attcggtttc gtttttttgg
    48961 taaagtaaag aaatatacag ccttttatgg ctaacattta taggagatat caatgacaca
    49021 agaaataaaa aaactacccg ttatattttt aggtcttttc tttatcacag ttggattgaa
    49081 ttggttcttg ctccctcacg atatagcttc cgccggagtg ggcgccatcg gacatttagt
    49141 tgaaacggcc ttttctatcc aacgctcagt tactgtttgg agcatcaatc ttatgatgct
    49201 gcttctagcc gctgtcctat taggaaaatc agtatttttt aagactgtag cgggaagtct
    49261 gctttttcct gttgttttag agattgttcc aaaagtggaa atgatctcct cacatttctt
    49321 ttcactgatt tcaggaagtc ttttgttcag tcttggggtt tacacattgt acacagtcgg
    49381 ggcctcaaat ggcggtataa cgataccgcc gattattttc cacaaatttt ttcggcttcc
    49441 aatgccgcaa ggacttttac ttaccaatag tcttatcgtc tttttgaatt attatgtttt
    49501 tggattgttg gagacactat tcgttctcct atctattaca gtcagttcat tgtttatgaa
    49561 aatactcatc cgcttgtccc ctgtgtcaag aaaatttgaa taaagctgga ttttgtcata
    49621 gcggaaacaa acgatatatt aaaaagagtg tgctataata aaccaagaaa ttgaataaag
    49681 cgagggatca atcaatgagc ttctctttag aagacatccg tcatttacta ttaaaagaaa
    49741 atctattaaa agaatttgtt tcaacaagag gctggcatct tgatgtacca gaaaaagctg
    49801 aatttcttca gttaagttat gattcaagaa aagctgatgc ttctactttg tttttctgta
    49861 aaggaatgaa tttcaaagaa gaatatttgg attcagcaat cgaacagggt attcaatatt
    49921 atgtatcaga acaaccatac gaaaattcag cagtaggaat catcgtaacg gatatccgta
    49981 aagcaatggc gcttcttgct atggcttttt acgactatcc gcaaaataaa ttgaaagtga
    50041 tcggattcac tggaacaaaa ggtaaaacaa ctgctgcgta ctttacaaaa gcaatcttgg
    50101 atcacacaac aaataaaaaa acagcattgc tttctactat gaatacaacg ttagatggca
    50161 aaacatattt caaatcccat ttgacaacgc ctgagtcatt agatttatat cgtatgatgt
    50221 cagaagcagt tgaaaatggt atgactcatc tagtgatgga agtttcttca caagcttaca
    50281 aaacacaacg cgtatacggc ttgactttag atgtcggaat cttcttgaat atctcgcctg
    50341 accatatcag tccgatcgaa catccgacat ttgatgacta tttctattgc aagcgacaat
    50401 tgatcttgaa ttcaaaaaca gttgttttaa atcatgaaag tgactatttt gatttactta
    50461 gggaaacagc cgatctattc cagattccaa cgatcactta tggtcgttcg gaagaaagca
    50521 attatcaagt gatccgttca gataaaggta ctcacggttt tactttatct tctcatgaag
    50581 atcgcttagc tatctgcgat actgcttatg atattttgct ggctggagga ttcaaccaag
    50641 aaaatgcagc cagtgcgatc attgccgcag cactaacagg tgcctccagt caagatgcac
    50701 aagacggatt aaaagaagct cgtgtaccag gccgaatgga tcaattgatc caatccaatg
    50761 gagcgcatgt ctatgtggac tatgcacata attatctaag cttgaaaaca ttgctgaaat
    50821 ttgccaaaaa tgaacatcca gatggccgtg taattgttgt attaggcagc ccaggaaaca
    50881 aagcaatctc ccgtcgacat gattttggaa aagtgctatc agaaacagct gacatcgcct
    50941 ttttgacggc agatgaccca gcatttgaag atccgaaaaa aatcgcggaa gaaatcaatg
    51001 aagcaattac taatccagat ttgatcgttc attatgaaat ggatcgtcct gaagcgattc
    51061 gacgcgcttt agcagaaagc gctccgcaag attcagtcgt tattgcggga aaaggcgtgg
    51121 atccctatca aaaaatcaat ggtgtagatg aaccttatga aggggattat gcaatcgtga
    51181 agcggttgat tgaagaataa tggtatttat atactagtgg tttcccattt ctaagaaaaa
    51241 aagggactgt gattttttgt cacagttcct tttttcttag aaatcatttt aacttttcac
    51301 tagctaattc tgctgccttt tctctttctt catttaataa tttattatca tagaatttga
    51361 taaatgggaa ccagataatg aatgcgatga ttgcacaaat gactgctaac acagcagctt
    51421 tccaatcacc accactacca acaaatgctc cgatcccgac tggtgaaggc cacggcatct
    51481 gtgcaagcat cggtttgacg atttccagcc gaatggcaaa ataagcgagt gtagcagaag
    51541 ccatcggagc taagaaaaac ggaaccgcta aatagggatt gtagacgatt ggcatcccga
    51601 aaatgattgg ttcattgata ttgaataatc ctggtacaag tgaggctttt cctaacactt
    51661 tcagctgatc agatttcgcg aggaatgcaa taaagatgat caatcctaaa gtcgcacctg
    51721 atccaccaac ggttacataa gaattgttga attctcctgc caacggataa tttgcgcctt
    51781 gtgcgttagc tgccatatta gctaatacga tcggggtcaa gaaagaagtg atgatattcg
    51841 ctccatggat ccctacgatc cacaatgcat ggatcaagaa ataaatcacc atgacaccaa
    51901 gccatgtatt cgtcaactgc gtaacaaacc caaatgggat agcaatcatt ttgaagatat
    51961 ccgttcctag tgcaactaat aatccattga tgatcatcac cacaaacgca atgacaaatg
    52021 ttgggatcag agcagtgaaa gaacgagaaa ctcctggcgg aacaacatct ggcattttta
    52081 tgacccaatt tctcttgaca cacatacaat acaattcgac cgcaataatc gacataataa
    52141 tagctgtaaa gattcctgaa gttcctaaac gttcgacaaa agagcccatc ctaataccat
    52201 ttactacagt ttctgtctca ttgatagaag caatcaagct gattttacca tcagtcatga
    52261 tcaattcagg gatacacata aagaatgcaa aaacagatag taatgccccc gtgagcggat
    52321 taacatttaa tttttgttca tctcgttcaa ttgacgttaa ttcataagca aacacaatgg
    52381 caaagtaaat agataaaatc cccatcgtca ttgtattgac gatcatgtac aagtcactaa
    52441 ctttgaaaaa agttgcatta aaaaatcctt ctaaaaatgg gaacggtaat ggcaaaatat
    52501 ttaaaaccaa aaacatcgag cctacaatcg tgaaaggaat agaagccatc cccgctgcca
    52561 tgacagcccg aacgatttta agttgcgcaa ttttccccat aggtcccatc aggtatttct
    52621 gcaaaaaatc aaacattagt tattctcctt tcctaaatat aacgcttttt catattgttt
    52681 aatacggata tactgttggt cttggttgag tgaaattttc tttaaacgat actgtataaa
    52741 tgcactggca aaaataccgc ttacaacaag aatgaaaaca aataactgtc ctccattgtt
    52801 atttgccata aaaggataca agaatgtaaa tcctgaggta aacaacactg gaatcactaa
    52861 taaattaaag acactctgga acaaaaaata ccactttgtc catggaacgt tcgtttggtg
    52921 ttttcgataa agctttactt gttctcctac tgcaggcaaa atagctaaaa tcagaatcat
    52981 cggtaaacta cttcctaaac ttttagctga tagaagcaga atcatccatt gcatgttcat
    53041 gaaaaagaaa aaggcagtca ggtaacgtac gattagataa cgattgaaat acatgttttt
    53101 caaactaagt tgcttttttt ctaattcgat tttccttttt actgtatcct gcacaatgat
    53161 ccttcctttc tatttatttt tttgatacaa ataattcatt tcctgtgcaa cttccaataa
    53221 tgtcatcgtc gtcatcagat gatcttgtgc atggaccatg ataatttcca tttctatttt
    53281 tgtcccgctg gcatattctt tcagaagttg agtttgtgac tgatgcgcat gaagaatctc
    53341 ttcatttgct tgtcgcaact tctcttctac ttcttcaaac atctctttac gcatcgagcg
    53401 aaatgcttca tgtatcagtg tccgtgcatt tccgctatgg aaaatgatat caaaagaagt
    53461 cacttgtagt gtttcactgt ttattttttc agccatctgt tttcctcctt attcgatcag
    53521 tttgataaat ttactgctga aattctcaaa aataggttca gctaagattt cctgctgtac
    53581 ttttagctgg tcaactaacc taacgattgc tttagtcacg accgtaattc cttcattttc
    53641 gacataagaa ggcgaaacta aaaaaacaaa atgaatttct tgatattgat cccactgcat
    53701 cccagaagga atcaatgcaa cggctacctt tgtttcgatt ccaactggaa cagcgggatg
    53761 tgggactgcc actgtatcac tgaatatgat ttgtcccata ttttcacgtt gctggatctg
    53821 ctttcgcatt tctcttatat atccttcttc ttcatttatg ctcagctttt gcagcaaatc
    53881 atgaagaatt tcttcctttt tcggttcgta cgtataagtc ttgaaaaatt tttcagacaa
    53941 ctgttcggtg taaatctgct ttttttgctg tagagaaaat gctggtatcg gtctatctga
    54001 ggaatgatag ggtatagatt ctccaactac ctttcgtatt ttacgaacat catcttcatt
    54061 caaaaaaata ctgacatgta aaactggaat tttgaaaaac attgtcgaaa gatcaataga
    54121 agaaataatc aggtcgattc cttttaaagt tgtttcattg atctcataat agccttttac
    54181 acttaccact gtaatatttt taccgaattc actgactacg cgattcttta atagttgggc
    54241 actgccgtaa cccgttgcac agataatcaa tgcatgtagt ttatgcgcag ctctttcttt
    54301 ttccaatgcc gccatgagat gcaaagccaa ataggcccat tcatcttcat tgatggtata
    54361 gtttttcaaa gccggcatgt tgctgaaatg cctttttact gcgtcaaaga ctttgggatt
    54421 ttctttcttt atctcctcag tcaatgggtt ctcaatgcga atacctcggc tcaatcgaat
    54481 catcatcggt gacaaatgat cgagtagtcc attgaaaagc tggagatcct ctactaatga
    54541 aaaatgaaat tcctgagaca atcttttcag aactttcgct aattcctttg atagttcctg
    54601 atcattttga ttttctttgt gattcgactt agccatgaga tgtaatgtca aataagcaat
    54661 ttcttcttcg ggaaacgata cacctgcgat tacctcaata cgttgaacga tccgctgcgc
    54721 cacttgatac tctactcgct tagaaacttc ttgttcgatg cctaattcct tgatttcaaa
    54781 cccttctcgg agccgtttga tccccaaagc caagtgtaaa gtcagattct gtatgataaa
    54841 atccgaaact tttaacttag cttctcttgt ttcatcgaga atgataatga ctagctcttc
    54901 aaaactgatg tctgggaaaa aacggctttg ccctaaatat tctttcaatg aatttccata
    54961 atggtttcca aaaaaagtat ccatgataaa atgccgtcga tttctttctt ccccttcgat
    55021 ccatgtccct tgaccatgct tagaaacgat ttttagtgaa tatggaatca atcgctcctt
    55081 gatttcttgc atgtcctttg tcaaactgga acgactgata taaagctctt ctgccaaatc
    55141 atccataaaa agaatggcat cttccaaaag caattggttc aatatatact tttgtcgatc
    55201 ttcggactca taaaatcctt gcggttctct agcatatcca ggtactattt cttgccgact
    55261 caaaaacaag tcaaatgtca gtctttgtaa aatatgcagt tggtagccat aacctggttt
    55321 agcaatgatc ttacctccgt ttttttctac taactctttg atccgctgca agtaattacg
    55381 gattgtccga tcagataata acaattcaga agctaaacgt tgactggtga catactcctt
    55441 cttgtgatca atcaaatatc tcaacagcaa tttttccttc tgtttcatta tcatccactc
    55501 ctattccatc atatgttctc ttcgatcacc tctgctaact tctggatgcc tgtagggatt
    55561 gggacatacg cttggaaagg gatactaaca acaggctttc caacagattc tcctaatttt
    55621 ttgaatttat ccaaaaacat cgtcgtttgc gggctgatca gaaataaatc aaaatcacta
    55681 ttcttaatca tattatcgcc ttctgtagct gaaactgcat ctacgagtac ctcttctctt
    55741 ttttgcttaa agaaatccgt tgtctttgag gccatcatcg aggatgacat tcctgccgca
    55801 caaataatca atgctttttt cataaatcaa tcactccttt tatttttata aaccaagcat
    55861 atcttgtaag cgttttctat tcaaaatata tatttccgta gcattgcgga aaaaatgtgt
    55921 atcatatctt gaataataat ttctggcacc gtgatatact agtgatagaa ttttttcagg
    55981 aggggattta gtgagtatca cagtgaatat tttgtataca agtacaaatg gacaagccag
    56041 aaaatttgca gaagaaatgg tcgaaagaaa cattgtcaaa gcgattcgtg cagaagaagg
    56101 aaacgagaaa tatgactatt actttccact agaagatcca gaatctcttt tactgatcga
    56161 ccgttggaaa gatgaagaag caatcgaaaa gcatcacaaa tccgaaatga tggctcaaat
    56221 aaacgaactc cgtaaaaagt ataaattaaa aatgaaagtc gaacgtttca ctgatttacc
    56281 gtaaaaagat acacatggaa tgatagcaat ttatcatcca tgtgtatctt cactttttcc
    56341 ttatttttta ttcgatctca tctaatgatt caaaccgtgt ttttctctta tttttcggat
    56401 aagtatttca gtcaccccaa tatacatgat tcctaaacat accccaagga tattctcaaa
    56461 aatgcggatc gttactgctc ctggaacccc gaataaactg gcagtgattg ccaaagcacc
    56521 aaaagaatta aaaactgttt tatatctata ggtagaacaa acacctaaag ctagaccacc
    56581 taatataccg acccagttaa aaggaataaa ttggctgata ccaataaata aaacacatcc
    56641 aatcaatgag ccaatgattc ggtctactgc tcgttctttg aaaccaatcg acatcaatcc
    56701 atagctagat acaatagaag aaaatgcaaa ccctgcccac atcaatcgct gaaaagggac
    56761 atactctcct gcaacgatca aaagactaat gccaaatgca tagatgagca tccaaatttt
    56821 ttcctgcgaa tacatgcctt tcaaaaaaat ctctttaaac aagcttttgt ctttgttctt
    56881 ttctcgatgt tttctgtaaa ggagaactga aaaccaacaa aaaaacaaaa ataataagct
    56941 acttgtttgt gtaaagaaat tcttgttcaa cgaatcttta ggtaacgaat aaacaataaa
    57001 gagatatgaa aagccgtaca aagaagcatt ccccattttg ggatcactag cggttgccat
    57061 taatatgctg cttagtaaaa taaaatgaat caacatgccc ataactgacc atttgatcag
    57121 ctggacatac ggtgctacta atagtgagaa catgacgatt gctaaaccta tgatcgaatg
    57181 ggaaatctta taaccaaagt caacaaaacg aatactcatc aacatacaga ataaaaccac
    57241 agcgtatggt ttatgcttcg attcaaataa tgttgtaatt ataatgataa aacaaatggc
    57301 aaacaatacg atgaataatg atcgtaaaaa caatgaacaa atatacatgc acttttcttt
    57361 tttagaagct gcttctcgta ttttttgttt taaaataaac ggatctagtt gtagagactg
    57421 ataaaaatcc acctgttgtc gtcctttctt tttactttta ttttttacag tcatctatga
    57481 caggttgtaa atactatgga acatcatatg gcgttgtcat tttcttgtca actatttttc
    57541 ctattcatgt ttttataaaa aaacatatcg ttttcttgta tgattaaatc accacaaaat
    57601 aaacaactga gagaacgata tgctttatga atggttctat caaaaaaatt ctgagatcaa
    57661 tagacaaaaa tttgatgatt acagaggtct cttacgaaac cttacagaag aaaaaaacat
    57721 tgatcgttgc tgcagttctc ttccctgctc catgtgtctg tagaaattgt ggttctgctg
    57781 tggtagatgg aaataggaaa ttaatggtgg tgaaaaacaa gaagaaggaa accattgtcc
    57841 actttgaata atataatcat atgccaatgg ttatacgcct aaaaaagcag cgctatacct
    57901 gtaaaaactg tcgaagccat tggaacgctc aaagttattt tatccgtcca aggcactcga
    57961 tttcaaatca tgtcagacat aaaatcactt ctttactgac tgaaaaagtg tcgttatttt
    58021 ttatttcgaa aagttgttag gtatctttga caaccgttat tcgcacattg aaagagttga
    58081 gaagctattt accaaagtct tccaaaagaa ttctgtcttg agtgttgagg gttgtgaatt
    58141 tcgttctcac gtttccgttg aggataaact gagttttatt tccgcggatg gcgagacaga
    58201 aaaattaatc gagaaaattt acctacacaa aaaattcctc gattaacaaa ctatttcctt
    58261 agctgcacta atcctaaaga aatagaattc ttagttacag acatgaacgc cacctacttt
    58321 cagctcacca aacatgttct accaaatgcg aaattggtga ttgatcgatt acttggtttt
    58381 tccacgcctt tcaaggaggc gtaaccttta ttcacgagtt ggttgaagct ttccgagaca
    58441 aaagacccga cttgtttttc tccttattga caaagagcca ttaaaactag agaaaaaatt
    58501 acaactgatc gctgattatt tgtagaaaga aaatcaaagt attacccaat aaacttgagt
    58561 cattaggcaa aaagcactgc gaaactcaag aatgattttc gcagtgtttt tgtatatttt
    58621 ttattaacta gtattactac aaaggtttat ttttcacttc tcaacgcagc acaaaattgt
    58681 ctttacttat ttactggttg ggttcaacct tctctactcc gatactaata tttgtttgta
    58741 taccccttct aaaatcggta gtttccattc aattgatggg tactagttga ttttaaaaac
    58801 tatgcttatt caatttttta ttttagctca tatatttcgt ttctttctaa attttatact
    58861 gatgaaaaca agtagcacac ccaatattga caatataaac tggctaatga tggtttctcc
    58921 agtttttgga agatgcttat ttccactgct tgttggattg tttcctctta tatctgagct
    58981 atcagcaact tttctattct cttttgttaa aaagatcgcc acttcttgtt ctttttcgat
    59041 cttgaaagtt actggtgtcg catccaattc ataccccgtt ggcgcttgag tttctaccag
    59101 ctgatatgct cctggtgcta agccatctat cgccagtttt ccatctgctc ctgtggttag
    59161 acctgactgc agaacggttc cattggcatc ttgtaactca aaaacagctc cttgcaggac
    59221 ttctccgctt tggtcatcga tctttgtcaa cacgacaccg cctggtgtaa gtcgattttc
    59281 tttcgtcaat tctaccaccg ctgtctgact tctttcgatc tcaaactcga ttggtgtcgc
    59341 atccaattca taccccgttg gcgcttgggt ttctaccagc tgatacactc ctggtgctaa
    59401 gccgtcaatc gccagttttc catctgctcc tgtggttaga cctgactgca gaacggttcc
    59461 attggcatct tgtaactcaa aaacagctcc ttgcaggact tccccgcttt ggtcatcgat
    59521 ctttgtcaac acgacaccgc ctggtgtaag tcggtttgct ttcgtcaatt ctaccaccgc
    59581 tgtctgactt ctttcgatct caaactcgat cggtgtcgca tctaattcat accccgttgg
    59641 cgcttgagtt tctaccagct gatatgctcc tggtgctaaa ccgtcaattg ccagttttcc
    59701 atcttctcct gtagttagac cggtttgtag cgtttctcct tctcggttct gtaactcaaa
    59761 aacagctcct tgcaggattt ccccgctttg gtcatcgatc tttgtcaaca cgacaccgcc
    59821 tggtgtaag
//
LOCUS       DAIGTA010000012        57914 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.012, whole genome shotgun sequence.
ACCESSION   DAIGTA010000012 DAIGTA010000000
VERSION     DAIGTA010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.012"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            271..837
                     /gene="amaP"
                     /locus_tag="NOB43_000738"
     CDS             271..837
                     /gene="amaP"
                     /locus_tag="NOB43_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI0981625.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            850..1038
                     /locus_tag="NOB43_000739"
     CDS             850..1038
                     /locus_tag="NOB43_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI0981626.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1051..1608
                     /locus_tag="NOB43_000740"
     CDS             1051..1608
                     /locus_tag="NOB43_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0981627.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1640..1882
                     /locus_tag="NOB43_000741"
     CDS             1640..1882
                     /locus_tag="NOB43_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0981628.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            2223..3437
                     /locus_tag="NOB43_000742"
     CDS             2223..3437
                     /locus_tag="NOB43_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HCI0981629.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            3468..4895
                     /locus_tag="NOB43_000743"
     CDS             3468..4895
                     /locus_tag="NOB43_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0981630.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            4918..5844
                     /gene="glsA"
                     /locus_tag="NOB43_000744"
     CDS             4918..5844
                     /gene="glsA"
                     /locus_tag="NOB43_000744"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HCI0981631.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6052..7512
                     /locus_tag="NOB43_000745"
     CDS             6052..7512
                     /locus_tag="NOB43_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981632.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIVLSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            7733..9496
                     /locus_tag="NOB43_000746"
     CDS             7733..9496
                     /locus_tag="NOB43_000746"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCI0981633.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            9580..10038
                     /locus_tag="NOB43_000747"
     CDS             9580..10038
                     /locus_tag="NOB43_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCI0981634.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10147..10830
                     /locus_tag="NOB43_000748"
     CDS             10147..10830
                     /locus_tag="NOB43_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCI0981635.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            10977..11591
                     /locus_tag="NOB43_000749"
     CDS             10977..11591
                     /locus_tag="NOB43_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HCI0981636.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            11607..11813
                     /locus_tag="NOB43_000750"
     CDS             11607..11813
                     /locus_tag="NOB43_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981637.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            12352..12909
                     /locus_tag="NOB43_000751"
                     /pseudo
     CDS             12352..12909
                     /locus_tag="NOB43_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            12967..15006
                     /locus_tag="NOB43_000752"
     CDS             12967..15006
                     /locus_tag="NOB43_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HCI0981638.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(15115..16266)
                     /locus_tag="NOB43_000753"
     CDS             complement(15115..16266)
                     /locus_tag="NOB43_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCI0981639.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(16420..16950)
                     /locus_tag="NOB43_000754"
     CDS             complement(16420..16950)
                     /locus_tag="NOB43_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI0981640.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(17049..17399)
                     /locus_tag="NOB43_000755"
     CDS             complement(17049..17399)
                     /locus_tag="NOB43_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HCI0981641.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(17556..19085)
                     /gene="ahpF"
                     /locus_tag="NOB43_000756"
     CDS             complement(17556..19085)
                     /gene="ahpF"
                     /locus_tag="NOB43_000756"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCI0981642.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(19095..19658)
                     /gene="ahpC"
                     /locus_tag="NOB43_000757"
     CDS             complement(19095..19658)
                     /gene="ahpC"
                     /locus_tag="NOB43_000757"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCI0981643.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(19802..20464)
                     /locus_tag="NOB43_000758"
     CDS             complement(19802..20464)
                     /locus_tag="NOB43_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0981644.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            20648..22294
                     /locus_tag="NOB43_000759"
     CDS             20648..22294
                     /locus_tag="NOB43_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCI0981645.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            22285..23367
                     /gene="uxuA"
                     /locus_tag="NOB43_000760"
     CDS             22285..23367
                     /gene="uxuA"
                     /locus_tag="NOB43_000760"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI0981646.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDIGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(23475..25028)
                     /locus_tag="NOB43_000761"
                     /pseudo
     CDS             complement(23475..25028)
                     /locus_tag="NOB43_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25176..26317
                     /locus_tag="NOB43_000762"
                     /pseudo
     CDS             25176..26317
                     /locus_tag="NOB43_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(26443..27522)
                     /locus_tag="NOB43_000763"
     CDS             complement(26443..27522)
                     /locus_tag="NOB43_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0981647.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(27625..28065)
                     /locus_tag="NOB43_000764"
     CDS             complement(27625..28065)
                     /locus_tag="NOB43_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0981648.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(28122..28532)
                     /locus_tag="NOB43_000765"
     CDS             complement(28122..28532)
                     /locus_tag="NOB43_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI0981649.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(28712..29146)
                     /locus_tag="NOB43_000766"
     CDS             complement(28712..29146)
                     /locus_tag="NOB43_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0981650.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(29246..30094)
                     /locus_tag="NOB43_000767"
     CDS             complement(29246..30094)
                     /locus_tag="NOB43_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0981651.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            30483..32249
                     /locus_tag="NOB43_000768"
     CDS             30483..32249
                     /locus_tag="NOB43_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HCI0981652.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            32351..33610
                     /locus_tag="NOB43_000769"
     CDS             32351..33610
                     /locus_tag="NOB43_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0981653.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            33757..35058
                     /locus_tag="NOB43_000770"
     CDS             33757..35058
                     /locus_tag="NOB43_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0981654.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            35061..35912
                     /locus_tag="NOB43_000771"
     CDS             35061..35912
                     /locus_tag="NOB43_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0981655.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            35925..36740
                     /locus_tag="NOB43_000772"
     CDS             35925..36740
                     /locus_tag="NOB43_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HCI0981656.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            36891..38057
                     /locus_tag="NOB43_000773"
     CDS             36891..38057
                     /locus_tag="NOB43_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0981657.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            38287..38934
                     /locus_tag="NOB43_000774"
     CDS             38287..38934
                     /locus_tag="NOB43_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI0981658.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            39018..39962
                     /locus_tag="NOB43_000775"
     CDS             39018..39962
                     /locus_tag="NOB43_000775"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HCI0981659.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            40097..41548
                     /locus_tag="NOB43_000776"
     CDS             40097..41548
                     /locus_tag="NOB43_000776"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HCI0981660.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            41569..42405
                     /locus_tag="NOB43_000777"
     CDS             41569..42405
                     /locus_tag="NOB43_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI0981661.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            42405..43064
                     /locus_tag="NOB43_000778"
     CDS             42405..43064
                     /locus_tag="NOB43_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0981662.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            43190..43879
                     /locus_tag="NOB43_000779"
     CDS             43190..43879
                     /locus_tag="NOB43_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981663.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            43885..44841
                     /locus_tag="NOB43_000780"
     CDS             43885..44841
                     /locus_tag="NOB43_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HCI0981664.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            44885..45397
                     /locus_tag="NOB43_000781"
     CDS             44885..45397
                     /locus_tag="NOB43_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0981665.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(45653..46201)
                     /locus_tag="NOB43_000782"
     CDS             complement(45653..46201)
                     /locus_tag="NOB43_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0981666.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(46290..47471)
                     /locus_tag="NOB43_000783"
     CDS             complement(46290..47471)
                     /locus_tag="NOB43_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HCI0981667.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(47707..49215)
                     /locus_tag="NOB43_000784"
     CDS             complement(47707..49215)
                     /locus_tag="NOB43_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HCI0981668.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            49374..49565
                     /locus_tag="NOB43_000785"
     CDS             49374..49565
                     /locus_tag="NOB43_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981669.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            49768..50685
                     /locus_tag="NOB43_000786"
     CDS             49768..50685
                     /locus_tag="NOB43_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HCI0981670.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            50678..51751
                     /locus_tag="NOB43_000787"
     CDS             50678..51751
                     /locus_tag="NOB43_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981671.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            51899..52417
                     /locus_tag="NOB43_000788"
     CDS             51899..52417
                     /locus_tag="NOB43_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981672.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            52398..52790
                     /locus_tag="NOB43_000789"
     CDS             52398..52790
                     /locus_tag="NOB43_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HCI0981673.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            52866..53801
                     /locus_tag="NOB43_000790"
     CDS             52866..53801
                     /locus_tag="NOB43_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HCI0981674.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            53934..54713
                     /locus_tag="NOB43_000791"
     CDS             53934..54713
                     /locus_tag="NOB43_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI0981675.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            54706..55023
                     /locus_tag="NOB43_000792"
     CDS             54706..55023
                     /locus_tag="NOB43_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI0981676.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            55267..56877
                     /locus_tag="NOB43_000793"
     CDS             55267..56877
                     /locus_tag="NOB43_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0981677.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            57034..57882
                     /locus_tag="NOB43_000794"
     CDS             57034..57882
                     /locus_tag="NOB43_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0981678.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        19266 a        10228 c        11305 g        17115 t
ORIGIN      
        1 taaatagaat cttgtaataa taactgagca taatctttgc aatttttaat cttgaataat
       61 atcctttaag tatagccagc aatcaaaagt aaatagagaa taagtaagca attgttattt
      121 cagtatcaga ctggcaataa aacgccgtta tgatccagca atgtttggta gcgctttatt
      181 tactgatgct atgctaactg ttcgctatct atactgtgat tgtcggtaga gttatttaca
      241 gggtaaaaat aagtttatag gaggtggaaa atgaataagg ggttaaaaat aatcggtgtt
      301 atcatgagtt tactgctact ttcagtattt ctagcgattg cgttgatcaa tgcgccgtat
      361 attatgcctg aacaattgga acgatttcgc ttctttactt taacgaatta ctacatgcaa
      421 caatatattt tctgggcagc tgtagtattt gccgttcttg ctattatcat cttgctagtc
      481 gttcttttct atccaaagtc aagaggaact ttcgttatga aacgggaaga tggcaaacta
      541 acaatcgaca aaaaagcgat cgaagggttg gtacgttccc atttacacga agaagagttc
      601 attcattcac ctaaagtacg gatacgttca acgaaaaatc gaatccatat ccatgtcaac
      661 ggagacttga aacgaacttc ttcattagta gggaaaacag gtgtattgat gcaagatatc
      721 gaagaagaag taactaaagt actcggaaca aaagaaacgg tcaaagtggc agtcacatac
      781 agcggttatg aagaacaaga agatacaaga gactacaagc actctcgagt ggaataggag
      841 ggccaaataa tgaaagaact attttcagca tacaagctcc ctattatctt tgggggtctt
      901 ggactactgc tagctgtttt atggttaacg attggatttt tcaagacatt gttgatcata
      961 atcatgacag caattggcgc aggaatcggt ttttatttga aacagtcagg aatagttgat
     1021 caatttttta aatcatagga ggaaacaaag atggaaaaca aaaacatgaa tacaacaaat
     1081 ggatcagttt tggcaaatga aaaaggagaa aaccgcatga tgaatggtga attgacttat
     1141 gaagacaaag tcatccaaaa aatcatcggt tatgcattga aagatgtaga tggtctattg
     1201 acattagatg gcggattttt ctcaaatatg gctgaaaaat tagtcaacac agataacgta
     1261 acagcaggta tcaatacaga agtaggtaag aaacaagtag ctgtggatct agatgtgatc
     1321 gtagaatacg gtaaagacat cgaagatatt tacaaccaaa tcaaagaatt gatcagtact
     1381 gaagtaaaca atatgacaca tttagatgtt atcgaagtga atgtgaatgt tgcagacatc
     1441 aaaacacaag aagaatacca aaaagatcaa gaaacagtac aagacaaagt aacagaagca
     1501 gcaaaatcca caggacaatt tgcttcacgc caaacagata aagcaaaatc tgctgtaggc
     1561 aaaggtgcac aaaaagtcaa agaaaataac gaaccacgtg tacaataaga agtaagaagt
     1621 cagttaggag gaatttaaaa tgggatttat ttgggcatta atcgtcggcg gtatcattgg
     1681 agcaattgca ggagcaatca cgaataaagg atcatcaatg gggatcatcg caaacatcat
     1741 tgctggttta gtaggttcag caattggaca agctttacta ggaacttggg gaccaacaat
     1801 tgcaggaatg gctatcattc catcattgat cggtgcaatc attttagtat tagtcgtttc
     1861 attctttgca cgtaaattat aagcaaattg aagaaaaact tatgttgaaa tgaagaacaa
     1921 atttgagaac cgtagcgaca ctcgctgcgg ttctttttta tatattttat atgaagtatt
     1981 ctttattcct tatgaaaaaa tatctttaaa aataaaaaaa gacgaaaata aacggttttc
     2041 tataaaaaga agaccgttta ttttttgtct ttatttgtgt gaaaaacgaa aaagagcaca
     2101 acacatcaag cttttattaa ttgtctgtct tttataaatg caagtattaa ttcaaaaaaa
     2161 cagaagaaaa aaacaactac accttctttt atactcgtaa tcgtagaaag gaggcgaaaa
     2221 aaatgaatac attacctatc aatacaggag atacagcatt catgatttta tgtacagcaa
     2281 tggtttgcct gatgactcct ggtctagctt ttttttacgg cggattagca cggaagaata
     2341 atatactaac gatcatgtct caatcttttc tctccgttgg gataacaacg attatgtggg
     2401 tatttggtgg attcggattg gcctttggac gggatatcgg cggtgttatt ggaaacccgg
     2461 cagatttctt tttgatgaga catgttacaa gcttccccaa catgtttcat ggtgcaacga
     2521 ttccattttt aatgttcttt ctttaccaac tgatgtttat cgtgattacc gttcctttga
     2581 tgacaggagc ttttgcaggg agattgaatt taaaaggcta tattatactt gttatttttt
     2641 ggaatctgct gatttatttc cctgtttgcc actggatatg gggtggcgga tttttggatc
     2701 agatgggatt tagagatttc gctggtggag cagtcatcca cacgacagct ggattcggct
     2761 ctttagcatg tatcctcaca cttggtcaaa gaaagattcc tttaggagaa agaagtcagc
     2821 atagcagtct tatggcagct gctatcggta caggactgct ttggtttggc tggttcggtt
     2881 ttaattccgg tggtgcactt cgagcagatg aacaagcagt caatgcattt ggttcaacat
     2941 tcatcgctct tgcatttgcg atgattactt ggctgatcat tgcaaaagta aaaggaaatg
     3001 gctttgattt tgtcgacgta ctaacaggat ccgttgctgg attggcagcc attacgcctt
     3061 gtgccggtta tgtagaagca aaaagtgcca tgctgattgg gatcattgcg ggtatcgtct
     3121 gtcatgctgc tgttgatttt cgtaaaaaga aacaatggga tgatgcactt gatgtgtggg
     3181 gtgttcatgg catgggcgga ttcacaggta cgattctgat agggatcttt gcatctaaca
     3241 gccatttact aacgaatcca agcagctggt acttcttagg gattcaagtg attggtgtca
     3301 tcattactgc cgtgtatgcc tatgtgctga caacagtgat tttaaaatcg gcgatgcact
     3361 ttacaacgat cactactaca aaagaagaac aagaagaagg attggacttt ttcttctttg
     3421 gcaacaaact caattgaaac aaattcaaat agaaaagagg aagattcatg caacaaagca
     3481 aaacgaaaat tcctgcaaaa aaattaacgt tctttggctt tttggctatg accatctcaa
     3541 tggtcgtttc attatatgaa tatcccacat tcgcgacctc aggcttcagc ttagtatttt
     3601 tcttgttatt aggcggtttg ctatggttta tccctgtggc attgtgcgca gcagagatgg
     3661 caacggtgaa aggatgggaa aaaggcggtg tctatacttg ggtcagtcgc acattgggaa
     3721 aacgattcgg ttttgccgca atctttttcc aatggtttga gataacagtt ggctacttga
     3781 ccatgctgta tttcttaact ggtgcattat cctatgcaac gggtattggt gctatacaaa
     3841 acaataaata tctgaaattg gcaatcctat tgattatttt ctgggctatt ttactctcac
     3901 agttaaaagg aaccaaatac acttcattga ttgctcggat cggttttgta gctggtatct
     3961 tgttgccagc attagtcttg tttggcttag ggatccatta tgtcgcttca ggcgctccac
     4021 tacaaacgat actgtctatg aaaacattga ttcctgattt ttcgaaattg cctacgctgg
     4081 ttgtttttgt ttcctttatt ttagcatata tgggcgtaga aacatctgcc agtcatgcaa
     4141 atgaaatgga aaaccctaaa aaggattatc cattagcaat gtttgtattg gttattctgg
     4201 caatcatttt agatactttt ggcggattga ccgtcgctac tacagtacct caacatggtt
     4261 tgtctcttaa tacaggggtg attcaatcgt tagaattcct attaagacac attgatccaa
     4321 atcttgcatg gattgcgaaa attcttgcga ttcttgtttg tttaggtgtc atcggagaaa
     4381 ttgcttcttg ggtaacctct ccttcaaaag cacttcacgt agcagcagaa gaaggattac
     4441 ttcctgaata ttttgcaaaa gaaaacacac acggtgttcc tgctcatttg atgatcgcaa
     4501 atgggatcgt tgcaacaatc tgggcagccg tctttacatt aagcggcggg gggaataatc
     4561 tttcatttct tgcagcgatg tcattgactg ttgtaatcta cctgatgttg tactttatgt
     4621 ttttcgcggg ctatttgaag ctggttttta aagatgacag tcttgaaaga gcctatcagg
     4681 ttccaggcgg aaaagttgta aaagtaatcg ttgcttgttt aggtcttttg acttcacttt
     4741 ttgctttttg tatctcattt gttccacctg ctagtatcgc agctggacag catgggattt
     4801 atgaaacgat tctgattgtt tcttatctta tcgtcttagt tattccattt acgatctacg
     4861 catgccgtca taaattccag catgcagaaa aataaaaaat gaaagctggt tattcaaatg
     4921 gaagtaaaag aattagaaca attgattgga aaaaatttcc actattatca aacaggacaa
     4981 gtggcggatt acattccagc attagctgaa gtggatccca aacaattagg tatggcgatt
     5041 tatgatttgg atacaaaaca actgattgag ggaggagacg ccgatgtgcg ctttgccatc
     5101 gaaagcatgt caaaagttcc cgtattgtta ttagcaatca aagacaacgg aatagaaaaa
     5161 gtctttcaaa caatcaacac ggaaccaacc ggttttgcct tcaattctat catgaatatg
     5221 gaaatcaatc atcgcaaaca tccaatgaat ccttttgtta atgcaggagc gattgcaaca
     5281 acctcgttga ttgccggtaa agatgcagat gaaaaatttg agcgaatctt gtcatttatg
     5341 aaagagatct gtgatgatcc taatatcaca ttgaatgaag aaatctatca ttctgaatca
     5401 agaacaggtg atatcaatcg ctctcttgct tactatatga aaggtaatca aatgatcgaa
     5461 ggagacgtac cggagatact cgatgcttat ttcagacaat gctccctcaa tgtcaccgct
     5521 acaggcatag caaaattagc tgctgtgctg gcaaataaag gaattgctcc ttggaatggc
     5581 aaacaaatca ttactgaaga aagtgctaca atcgtcaaat caattatgac aactgctggt
     5641 ttgtatgatg aatcaggaga gttttccgtc catgttggtg tacctgcaaa aagcggtgta
     5701 ggcggcgggt tgatggcagc tgtgccaaat cgttacggca taggtgtctt cagcccggca
     5761 ctagatccat ttggtaacag cgcagctggt atccaattgt tgaaagatgt agtcaaagaa
     5821 ctagacgctg acatctttga ataaccattc ttgaaagagg ctggggtaaa agtccaaacg
     5881 gctcaaagct acctacaatg aggctgaaat tgtgagcttg tttgactttt gtcccagttt
     5941 ctttttttat tggtttttga aagggctttt ctaaataaaa aggaaacaaa aatacgattt
     6001 acagatatga ttaaataaaa tcataagaaa aactggaggc gtgtatcagg aatgctggaa
     6061 aattacatcg agcgaaatat atttagaaaa gtgtatctgt gtgaacaatt atttgaattc
     6121 caagaaatag acatcgaaca aacagctatt tctctaaggg tgactacacc aacgatcctt
     6181 cacgatctag aaagtctagc cgagtgtcta gaatattgta taaaagaaca agtaagagag
     6241 aagcataagt ataaactcgt attcaaacat ggtattgttc tttctgagct cacacagttt
     6301 ctgtacggtc aatcttattt tttaaagttt ttaagttatt attttaatgg tatattcacg
     6361 agtacagaac tggctgatct tgaatttatt tctttgagca aagtatatac aatcaaaaaa
     6421 atcgtattgg atttttttaa agaaaatgat tatttgaaaa ataaagaaat cattatccca
     6481 gaatttgact cgcggaacat cttgctagct ttagtacgtt atgtcaattg ggaaggctat
     6541 gaaaataaaa atccgtatgt agaagaagct tgtaacgagt tgattgatta tgtagagact
     6601 cattttttta aaagaagata ttcggaagat gaaaagtcct ttatcatacg aggaatagag
     6661 atcgcaatcg gaagaaaggc atttcccctt ggactgaaag aagaagataa gaaaagcgca
     6721 gaaacgaagc cgttatttca attagtctgt caaggattgg aagagcaaaa aggaattcta
     6781 gacttacaag aagaagatgt ctattatatt ttttctttgt tcaacagtag aaattatacc
     6841 aatgagaaca tggagctgtt aagaaaagat ttcgaagttg tttataaaaa ttttgttctc
     6901 aatgacctat cactgaatga attgatttta cagattatta gtatcgctga aatcgacgat
     6961 gcagaaaatt ttattttcaa gcaatccttt ttacaatttg tccgtacgtt gtgggcagat
     7021 ggacaagtat ttttaccgga aaggatctat cttctatcag aaaaagaaca acttctgtac
     7081 ggaaaaattg tagaaatatt ggaagagtgg aaaaagaaaa atcaaatcca actaagatgg
     7141 aatgaaaatt tcattcgaaa attcgtcaaa agtctttctt tgatcaacag tgaacaagcg
     7201 gggagacagg aaatagaaat ttttgttgtt tcagaaagtt cagtcaaaca atttttttat
     7261 cgaacccaat ttcatttgta tgcggaagaa ggcatcgctg aaataaatcc tattttattt
     7321 cgttcattag aagaattgcc tgatgaatgt ctatgtgcga aaaaaagagt ggttttgtgc
     7381 gatgctgcta gctatcaaaa tggattagaa actgaaaaga caaagatcta tccaatctca
     7441 ttaaaaggtg caaacatcca tttgtatcat attgctcagg aacttcacct attaaaaaaa
     7501 catatttctt gatgagacct taattaggag accttctaca aagcttttta attgtctgta
     7561 gaaggttttt atttgagtcc tgattcgtgc gaagatctac ttatataaca agctttctct
     7621 gaaatttttt taaaatgcta ttgacttaga gtcaactcta agtagtagaa tagataaagt
     7681 gtaacaaatc tattttcatt aaaagaagat agtacggagg agagaatgta ttatgagtac
     7741 agtattacat gtattggatg caatcaatag ccccgcagat gtcaaaaaat tatctgttga
     7801 ggaaatgaaa cagttggcag aagagatgcg ccaaaaaatc ttgcaaaagg acagcgatgt
     7861 aggtgggcac gttggtccga atctaggtgt agtagaatta acgattgcgt ttcattatgt
     7921 atttgattca ccaaaggata aaatcgtttg ggatgtttcc catcagtctt atggtcataa
     7981 gcttttaact ggtcgaaaaa atggttttga aaaaggacat taccgtgaag tgagcggata
     8041 ttccaaccaa catgaaagta aacatgacta ttttacagtg gggcacacat ctacatctat
     8101 cagcttagca acaggtttag ctaaagcgag agatctgaag aaagaatcag gaaatgtggt
     8161 agcatttatc ggtgacggct ccctaagtgg tggcttagct tttgaaggat tgaacaatgg
     8221 tggtgtttta caatccaatc taatcgtatt agtaaacgat aatgagatgt ctattgatga
     8281 gaatcatggc agtttatata aaaacttagc tgagcttcgt caaaccaacg gtaaaagcag
     8341 caataaccta tttaaagcaa tgggatttga ttatcgttac gtggataatg gaaacgatct
     8401 ggaaacggtg atccgtttat ttgaagaagt aaaagatatt gatcatccga ttgtacttca
     8461 cgtccatacg gaaaaaggtc gcggttatca gccggcaatc gataataaaa tgaaatatca
     8521 ttggcatgta ccatttgatc tgtccaccgg ggaggcaaag caagtaactt ctggagaaac
     8581 atttaatatg atcatcatgg attatttgga taagaaaatg caaacaagta cagctcctat
     8641 tgccgcagtc aatgcagcga taccaggcgc ctttggactg aaaacattcc aagaaaaaca
     8701 tccagatcat tattttgacg tggggatcgc tgaacagcac tctatcactt tcgcttctgc
     8761 tttggcttct cagggagtac gtccagtcgt cttccaatca agtactttct tgcaacgggc
     8821 atatgatcaa ttatcacatg atttagcgat caacgagaat ccagtgatta ttttagtcgg
     8881 tggcggaacg atctcagcta gtgaccgaac acaccaagga acatttgaca ttccttactt
     8941 atcaagtatc ccgaacatca aatatcttgc tccagcaaca aaagaggata tgatctctat
     9001 gctagattgg gcgttcgaac aaacagcgca gcctgtagca atccgaattc ctacacatgg
     9061 tgtagaacat ggtacagcta tcgcaaatga ttatagtatt ccagcctatc aaacagtaaa
     9121 taatggagga aaagtagcaa ttttagcttt aggcggtttt cttgaattag gaaaagaaac
     9181 agtaaaagct tttagaaaaa aaggaatcga agcaacgttg atcaatccag gaacgatcac
     9241 agaaaatgac gtagaaacat tagataaatt aaaagaaaca cacgaattag tcatcacatt
     9301 agaagatggt agtttgtcag gaggatttgg cgaaaatatc agtcgttatt atggtgattc
     9361 ttcaatgaac gtattaaatt ttggtgcaga gaaagaattc acggatagcg ttcctgtagg
     9421 gcagctttat gaacgttatc atttaacacc aaaacaaatc gttgaagata gtctgcgtgt
     9481 cttgaatatt caataattca ttatgctcac catccagata attgtttata ctagtatctg
     9541 gatggttttt tcattataaa aagcaaaggg gtggatgtta tgtatcagca agtagaagaa
     9601 tatgtcaaaa agttccaaga aaaatatcct agttatcaat cagaaaaatt aggtttcttt
     9661 tcatttgggg atacagaaaa aatggcagac gagttgagcg aactagttgt aaaaaagata
     9721 aagactggta catcaagtgg ttacgatctg tataaacaag agaatgagcc tttaccaaaa
     9781 gttggtcaat tagacgtggt cctgaatgga aaaaatgaac cagtttgtat catcaaaaat
     9841 ataaatgtga ccatcttgcc ttttagtgaa gtcacgaaag agcatgcttg gaaagaagga
     9901 gaaggggatc ggacattagc ttattggcgg aaagtccatg ctgagttttt taaacatgct
     9961 tataaagaag cgttgaacat agaatttaca gaagagaagc tggtcgtata cgaagaattt
    10021 gaagtaattt tcttttagta agaaaggtct gctgaaagaa atagctcatt attgtctcct
    10081 gaatagaaaa gggttacatt tttatatgaa gctgtatttt tatataacat tactggagga
    10141 gatattgtgg atacactgga acaaatcaaa ggcggagtcg tcgtttcttg tcaagctttg
    10201 gaaaacgagc cgctacacag ttcttttatt atggggagaa tggctttggc tgcaaaagaa
    10261 ggcggagcag ttggtattcg agcaaatacg acagaagata tcaatgaaat caagcgaatc
    10321 gttgatttac cggtaatagg gattatcaaa agagattacg atgggtcaga agtgtttatt
    10381 actgcgacag aaaaagaagt ggaagaactt ttggagacgc aagcagaaat cattgcactg
    10441 gatgcaactt ctcgtaaacg tccgacagaa aaaacaactg ctgaacttgt ccaaatgatt
    10501 cacgaacacg gtcggttagc tatggcagat atttcgactt ttgaggaagc gcttcaagcg
    10561 caagaagatg gttttgatct tttgtctacg actttagcag gctatacaga atattcacga
    10621 aagacgcaga cacctgattt tgatttattg aatcaaatca tagaacaagt cgatatccca
    10681 gtaattatgg aaggacatac tgactctcct gaacaagtag agaaagcata tgaattaggt
    10741 gctttttcag tcgtagttgg atctattatc acccgtccgc aattgatcac taaaagatat
    10801 gtcgaagccg caagtaaagc aaataactaa aaaacacgca cggcacagat tcttgacaaa
    10861 aaagaaaaat tgatagatag tttaaagcag attctaagaa gatgaaaaaa gcattacttt
    10921 tcattttgtc ttcaagatct gctttttaac gaattttata gaaagaaggc gaaaccatgt
    10981 ttgaacggag tccttcagaa ttgacagaac gtgaaaatta caagttgctg attggttcag
    11041 tcatccctag accagtagca gtagtaacga ctaaatcagc aaaagatata gtgaatatcg
    11101 cacccttcag ttacttcaat atcgtcagtt cgaatcgacc catcttatcc ttggcgatcc
    11161 agagaaaaca agatgcagta aaagacacag caaagaatat tcttgagaca agagaagctg
    11221 ttatccatat ccttgatgag gacaacgtag aagaagtaaa taaaacagca gccaatctgc
    11281 ctaatgagga aagcgaactg tacctgactg acttgacttt aactgattca gtaatcattt
    11341 cagtaccagc attgacagaa gcaaaagttc gttttgaaac atccttatat gaacatgtcg
    11401 agatacggaa taaaaataaa gtaacagctg atttattttt gctagaagta cagaaatatc
    11461 atttaaatga aacagtctat gatgataaga caggaaggat cgatccaaga aaattgaatg
    11521 ctgtaagccg tttggcagga aatgattatg cagcaatagg agaaattttc acgattgcac
    11581 gtcccgaata aaaaggagca ctagttatgt taaaaataag ctataaacca tcgacagatt
    11641 caaaagaaat gaaaaaagaa tatgaaacag tgaatgattt tctgcaaggg cagtacttag
    11701 aagttccgcc attgcaagac cattttgtcg ttactactgt tactttagat ggtaaggaaa
    11761 tagaaatgcc agatcaaacg attagcggat tgtttaatta ctttaacaaa taaatattta
    11821 ttccgaaaag tgaaaaaaca tataaaaaaa cacataaaac taaaaaatta tcaaagaatc
    11881 ctggtgcaac tgaaagaatt tgcaacggga ttctttcaac ttatttgtta tttttttcta
    11941 aaaaatatta aagattgtta aatttcacta tttcatttca aattccattg cctaatcatt
    12001 aggaaaagtc tatcatgaac tcgtaaatag aatatagtaa taaccttgtt aggtgaggct
    12061 cctatacaaa cataggctgt tgcccagaaa cgtcgaaagt cgccaatggg taaaacagaa
    12121 actgttggat taaggctttt tccaatagct aagaatgttt tctttacgtt gtatagtgct
    12181 aaaactcgga cgatgagatg atgctaggtc agaattcttg ttcgaaaagg tttctgacct
    12241 tttctttata tttttgtgac tgacttattt gatgagacaa actcgctcct cacctgacaa
    12301 gtggattgct gtgtgaggag gagatgcggt gaaaaaagat cgattggtgg aggtcgctcg
    12361 gattcacttc tggttgcaca atacaaccag aaaacacaac aagcaaaact gatctctatc
    12421 atgagagatt catatgtcga tattccaggt tacggaatga ataagataaa tgcagcttac
    12481 tcttatgggg gagttgattt attaaatcaa acattaaagg aaaatttcaa atttgaagct
    12541 ccctattatg caagtatcac atttcaagat tttatcgatt gcgttaatga actgtttcct
    12601 ggtggagtca agatcgatgc agaaaaatct ctagatttag atggcgtata tataaacaaa
    12661 ggagagcaag tgatggatgg taatacttta ctccagtatg ctcgatttcg ggaagacaaa
    12721 gaaggagact tcgggaggat cagaaggcag cagcaagtga tcaaagctat ctctcagcag
    12781 ctgaaagacg taacttcaat attcaagcta cccaaagcgg ttgggaaatt acttggtagt
    12841 atccaaacga accttccaga aagtgtgctt ctggattgtg gtatggattt cctcaaagac
    12901 atatgttaga ataaacaggt ataaatagtg aaataaagga atgacaagca agagaaggag
    12961 gaaaaaatga aaagaagtga caagcacggc aaaaatcgaa caggcgctta tattgccggc
    13021 gcagtgatct taatagcagc tgcgggtggc ggttattttt actaccagca ctatcaagaa
    13081 acccaagcag tagaagctgg agaaaagaca gttgagcaat ttgtccaagc tttgaacaag
    13141 ggagattata acaaagctgc agaaatgaca tcaaaaaagg cggcaaataa aagtgcatta
    13201 tctgaaaaag agatcttaga taaataccag aatatatacg gtgctgctga tgtcaaagga
    13261 cttcagatat cgaatctaaa agtagataaa aaagacgatt ctacttacag tttttcatat
    13321 aaagcaaaga tgaatacctc attaggtgaa ttgaaagatc tttcttataa aggaacatta
    13381 gacagaaatg atggtcaaac cacgatcaac tggcaaccca acttggtttt tccagaaatg
    13441 gaaggaaatg acaaagtaag cctgaccaca caagaagcag caagagggaa tattatagat
    13501 cgaaatggtg aaccattagc aacaacaggc aaactaaaac aattaggagt cgttccaagt
    13561 aaacttggag atggaggcga aaaaacagcc aatatcaaag cgattgcttc ctccttcgac
    13621 ttaacagaag atgctatcaa tcaggcgatt tcacaaagct gggtacaacc cgattacttt
    13681 gtcccattga aaatcattga tggagcaacg ccagaacttc cagctggagc taccattcaa
    13741 gaagtagacg gcagatatta tcctttgggt gaagcagctg ctcagctgat tggttacgtg
    13801 ggagatatca cagcagaaga tattgataag aatccagaat taagcagtaa tggaaaaatc
    13861 ggtcgctcag gtttggagat ggcttttgat aaggatcttc gtgggacaac aggtgggaaa
    13921 ttaagcatta cagatgcaga cggtgtagag aaaaaagttc tgatcgaaca tgaagttcaa
    13981 aatggcaaag atatcaaatt gacaatcgat gcgaaggcac aaaaaatagc ttttgacagt
    14041 ctaggaggaa aagctgcatc aactgttgcg acaacgccaa aaaccggtga tcttcttgcg
    14101 cttgctagct ctccaagcta tgatccaaac aaaatgacaa acgggatctc acaagaagat
    14161 tacaaagctt atgaagaaaa tcctgaacat ccattcatca gccgatttgc gacaggttat
    14221 gctcctggat ctacgtttaa aatgattaca gcagcaatcg gtctcgacaa cggcactatc
    14281 gatccaaatg aagtgttgac gatcaacggg cttaaatggc aaaaagacag ttcttgggga
    14341 tcttttaaaa caacgcgtgt cagtagtgat gtatcacaag tagacttaaa aactgctttg
    14401 atctattccg ataatatata tgcggcacaa gaaacgttga aaatgggtga gaaaaaattt
    14461 cgtacaggct tagataaatt catttttggt gaagaccttg atttgccaat tagtatgaat
    14521 ccagcacaaa tttctaatga agatagcttt aactcagata tcttgctagc tgatactgga
    14581 tatggacagg gcgaacttct aattactcct atccagcaag cagcaatgta ttctgttttt
    14641 accaacaatg gcacacttgt ctatcctaaa ttgattgcag ataaagagac aaaagataag
    14701 aagaatgtca tcagcgaaac agcagtacaa acgatcgtgc cagatctgag agaagttgtg
    14761 caagatgtaa atggtacagc acattctctt tctgctttag ggattccgtt ggcagcgaaa
    14821 actggtacag cggaaatcaa agaaaaacag gatgtaaagg ggcaagagaa cagtttcttg
    14881 tttgctttca atcttgataa ccaaggttat atgatggtca gcatgttgga aaataaagaa
    14941 gatgatgatt cagcaaccaa acgagcatcg gaactattgc aatacctcaa ccaaaattat
    15001 caataaaaaa ttgcttttta agtacagtaa aaggactgtg gcgttatcgt cacagtcctt
    15061 ttttcaaata aacggttttc acgatgtctc tttcacaact tctttttgat ttactcacac
    15121 ttcataaact ttttttgtaa aatatttgag aacaagtgga gaaataagtg tacttaataa
    15181 aatcacgata actaaaggtg aatagtactg tggttcgatc aattgacttt gctgtccaat
    15241 ttgtaaaatg atcaaagcca tttctccacg cgaaatcata ccagcaccga ccatcaatga
    15301 actatgttga gaaaaaccgg caatctgagc accaaaataa cctccaagca atttggtcaa
    15361 aatcgctaca agcgtcaata tagaaataaa gagtagttgt tcactaaagt cagaaaaatc
    15421 aacttctaat cctacactga caaaaaatac tggtataaat actgcatatc ctaaagcctc
    15481 tacattgtgg tatacttctt ctttaacctt tgtctgactg acagctatcc cagcaaaaaa
    15541 agcaccaatg acagagctaa gcccaacaag atccgctacg taagacattc ctaaacaaat
    15601 aactagcgat acgatgataa tagaagaatt tgcgtacact ttttctgcaa atgaaagtag
    15661 gaaaggcgca atccatttga ctaataagaa aataaaaaca aaataaatta gctgttcaat
    15721 caaaacaagc ggtaaagaag cattgctaga agcttccccc gttagaaaag ataggctgaa
    15781 acttagaact aaaacgacta aaatgtcatc taccacagaa gcacccaaaa ttgttgatcc
    15841 ttcttttgta ttcactacgt ttagttcttt taatacttct actgaaatac tgacagaagt
    15901 tgccgcaaga ataatcccaa agaaaatcgc ttcatttccc gaaacttgga atgctttgcc
    15961 tgtcaaccag ccaaaaacaa ccgggaagat gatcccaagc aaagcaacga acataccagg
    16021 tcggaaatat tttttcaaaa gagataaatc actttccaga ccagctaaaa acattaataa
    16081 gatcacacca atctccgaaa agtcatggac tagaatatca ggtttgaccc aattcaatcc
    16141 agcttggcct agcaaaacac caacaagtaa ttgtccaatc actgctggga tacctaatct
    16201 ccgcgagata tgtgagccaa tcgttgttga aatcaatatc aggcataaaa taccaataaa
    16261 ttccattctc atcattcctt tgtataaaat atagcccgaa cttagcataa catacattat
    16321 tgaaaaaata ggaaaatata ctcacaaaaa aaccaacaat ccaaaagatt tttttggatt
    16381 gttggttttt atacggtcta ttttaataac taaaaatgat taacgtatag tcatttttct
    16441 tattctgatg aaattgataa tctcctggat gcccatgaaa atcaaaataa agccgaatat
    16501 ttggaataga agcatcaaac ttttgaatgg attgaacaat aagacgaatc cgccaatcaa
    16561 caacagaata ctactataaa cactccaact tttagctttt gtattcatgc tgaagaacaa
    16621 ctggaacaag ctgttgatga taacagctaa tccaagaaga atcggcagga tagaaacgat
    16681 tgcaggtgca aaagcataga cgatcagagc taagatcagg aaaaaaagac cactgaacag
    16741 accgatactc caagaacctg ttttcctttt aaaacggtaa gcctcaaaaa gattcaacaa
    16801 cccaagcaaa acaagatagg cggtgatcag ataaccgata aaatgaaaaa cagcagaagg
    16861 gtttagcaca atcgcaatcc cagaaataat ataaacagca gctcttaata aggcgtattt
    16921 ttgaatattt tgtttaatcg tctcaaacat ataagaaaac ctcctttgac ttattttaac
    16981 gtgaactagt cattttacca aattaaatgt tacaaaatga gcgaaggaga agaatatctc
    17041 tggaaaaatc aacttctgag gatcttttcc atttttttgc cttttgctag ctcatcgatc
    17101 attttatcta aataacgaat ttctttcatc aagttatcct cgatgtcttc tactcgtaca
    17161 ccacaaacaa cacctgtaat caaggaacgt gaaggattgg ggacaggggc ttccgcaaaa
    17221 aattgttcga aagtcacttg tttttgtagt tgatattcta gttctgtttg ggaataaccc
    17281 gtcagccaac aaatgatttc atctacttcc tcttttatac gatcttttct ctccgctttt
    17341 gctacataca taggataaac gcttgcaaaa cttgtcgtaa aaatacgatt ttgcgccata
    17401 atcagtcacc tttctttttt tcaaattatt tactacttat agtatataag aaaaagagaa
    17461 gaaaaagcga ttattcaaaa aaacaaaaag gattgtgaca aaattcttgt caccatcctt
    17521 ttttccgctc tctgactttt tacaatcttc atagctcaag tgcgcatcag ataatcgaat
    17581 gctcctaaag ctgcagtagc tcctgaaccc attgaaacaa tgatttgttt gtatggacta
    17641 tctgtacaat caccagctgc gaaaacgccg gggatattcg ttgcgccatt tttctcggtc
    17701 actatttcat ttcttggatt catttcgatc gttctatcta gccaatccgt attagggagt
    17761 aagccgacta gaatgaatac tcctgaaaca gctagtgtat gcatctccat cgtacggcga
    17821 tcgatatagg agagagattc tacctgattc gtaccgctga tttctttcgt cgctgcatgt
    17881 ttgataacag tgacattcgc aagagagact agtttatcct gtaagatttg atctgctttt
    17941 aattctggta agaattctag aacatataca tgttttgcta acccagccaa atcgattgct
    18001 gcttcaacac cagaattacc accaccgata acagcaatct cttttccttt aaataaaggg
    18061 ccgtcacagt gtgggcaata agcaattcct ttatttttaa actctttttc gcctggtaca
    18121 ttgatagaac gccagtgcgc acctgtcgcg atgatggcgg tttttgcttt aagtgatata
    18181 ccgttagcta agccaatatt aataaaatgt tgctctttat ttaaggaaac ggcctgttga
    18241 ttcatcataa tgtcgatagg gtaactacgc acatgacttt ctacttgctg catcaatttt
    18301 ggaccttctg tgtaagaggt accaatcata ttttcaatcc ctagtgtttc aacgacttgt
    18361 ccgccgaaag aatcagcgac aagtcctgta cggattcctt tacgtgctgc atagatagct
    18421 gcactactag ctgctggtcc accgccaatc actaatacat cataaggttc tttttcaaac
    18481 aactcttctt caatcaaagg gccagtgatt ttttcaacaa tttgttcgat cgtcatgcgt
    18541 ccgctactaa attcttctcc atttaaaaac acagttggca ctgccatgat ttttttatca
    18601 tcgatttctt tttggaacat cccaccttca atcatcgtat gagtaatatt tggatttaat
    18661 acagctaata tattcaatgc ctgtacaacg tcggggcaat tatgacaagt caagctaaca
    18721 taactgtcaa aatgcaatgt ttgtgttatt tttttgattt taagactcaa agattcactg
    18781 attttcggtg cccgtccact aatttgtaac atagccagta aaaaagagga aaattcatga
    18841 ccgaggggga taccagcaaa aacgattcca ctttctttgc caactggatt gatagaaaaa
    18901 ctaggtgtgc gcatcgaatc tcttttttcc caagagattt taggagacat ttctgctatt
    18961 tccttcgtaa attcagctag tttttgacta ttttcactat tatccaaact aacagaaaaa
    19021 acaataggag attcaatcag tgctaaatat tgttcgagat tttgtttagt ttctttgtct
    19081 aacatatcca ccacctaaat ctttccaaca agatcaaaac ttggtttcaa tgtttcgcca
    19141 ctttctttcc attttgccgg acaaacttca cctgggtggg tacgtacata ttgagcagcg
    19201 cgaatcttat caatcagtgc actagcgtca cgaccgattc catctgcatt gatttccata
    19261 gcttgaacga ttccgtctgg atcaataata aatgttcctc gctgagctaa tccttgctct
    19321 tcatccaaaa catcaaaaat acgagaaatc tgatgagacg gatcaccgat catcacgtat
    19381 tcgattttac cgatagcatc tgatgtatca tgccatgctt tgtgagtaaa gtgggtatcg
    19441 gtagagcaag aaaagacttc aacacctaaa gatttcaatg tactgtattg ttcttgtaag
    19501 tcttctaatt cagtaggaca aacaaaagta aaatcagctg gatagaagca aagaatactc
    19561 cagttcccca taagatcttt ttcactgact tctaaaaatt ctccttgatg ataagcatgt
    19621 gcattaaatt cttcgatttt tttcccaatc aatgacatag taaaacctcc aataataatt
    19681 atttatttat aattattgta atttagttgg agttgcaaag tcaatggata ttttgttatt
    19741 taataaagat tactcaaaaa cgaaggttaa ttataaaaat agaagaggtc gcaagaaaat
    19801 gctactgctg gaaatactcg ggataacgtt gagtaacagt ttcctgttct ttcagcatca
    19861 tgtgtaagtg caatcccgtt tgaaatcgag cttcttctgg ttttttatca actaaagcct
    19921 tgagtaaatc ataatgttgt tccatgatcg tttcccatgg aagcccctga atggtcactc
    19981 gtaaccagcg gaaacgttct aaatgggtat tatggtcatc taaccagttc caaacttctt
    20041 ttcttcctgc aatttcgaaa caagcttcat gaaataaatt atctgcacgg aaaaaagcgc
    20101 gttcgtcatt tattttgact gctttttctt gttcttctaa aatcgtttct agcactattc
    20161 gtgtttgtgt gtccaatttg gaacaacatt caatcatgat ttgctcttcc aactgttctc
    20221 ggacaaagcg agcattttct gcagaaacaa gattaatttt ggaaacatac gtaccacttt
    20281 gaggtatcgt atacacgagt tcttgctgac gtagttgaat caatgcttcg cgaatgggag
    20341 tccggccgat agcaagatgt tcctccagtg ccttttcaga tattttcctt ccaggttcta
    20401 agtcagcata gataatttgt ttacgaatcg cttgataagc ttgtgattgc aagctgcttt
    20461 tcatctttat tcctccaaaa tcatttctat gaacgtagta taacagaaga ggtctgaaaa
    20521 acaatctggt atgtcacatt aactagtaaa tttgtataaa tagtaaaatt ttggttgaca
    20581 tagcgatttt tattgcataa aattcacttg aatacaaaaa ctaatatgtt agtttaggag
    20641 gggaaaaatg attgatttaa acaactggag gaactttatc cctgaattat ctcaaaaaga
    20701 agtagaaata cctcattttg accgtgcatc attaagagaa aatggacaaa aaaatcctgt
    20761 ctggatccat ttcggtggcg gaaatcttta tcgaggattt catgcagaaa tcgctcaacg
    20821 tttagcggat ctaggcgaat tgtccactgg tgtcattgtt tgtgaaacat tcgatgaaga
    20881 aataattgaa agggcttacc aagattttga tgatttgatt cttgaagtgg tcatgccaag
    20941 cagtggagag ttcgtcaaac gtatattagc tgcgacagct gacagtctgt attgtcatcc
    21001 agattgttct gaacactttg ataagatgat tcgacacttt gaaaatccta gtttacaatt
    21061 agttactttt gctattactg aaaaaggtta tcgattgaaa gatacaaata ataaatatat
    21121 aggaccgatt gcagtcgata taaaaaatgg tccaaagaag ccatcacata caatgagtat
    21181 tcttgctgtg ctactttata aacgtttttt atctggagct tggccgattg cacttgtctc
    21241 tacagataat ttttcacaaa acggtagtca attacgtact tctttgctaa cgatcgcaaa
    21301 agaatggcaa aaggaaggtt atgtacaaaa tacatttatc caatacttat cgaatgaaga
    21361 aattgttgcg tttccatgga cgatgattga tcgtatcacc ccgaatcctt ccttgtcagt
    21421 tagcaaaatg ttggcaaaag agggcttttc aaatatgtcg attttccaaa ccgcaaaagg
    21481 aaataatatt gctccatttg tcaatacaga ggacatccat tatttaatca tggaagatca
    21541 ttttcccaat ggacgtccga aattcgaaaa agctggggta ttcttgactg atcgtgcaac
    21601 ggtagataaa gcagatacga tgaaggtgac gacttgcctt aatcctttgc atacgtcttt
    21661 agctattatg ggttgtttac tggggtatag gagcatagct gaggagatga aagatccaga
    21721 tttatcgctg ctagtttctg aaatcgggta caatgaaggc ctcccagttg tggagtctcc
    21781 aggtatcatt gatccaaaga tctttctgga agaagtaatt actgtgcgct tttctaatcc
    21841 aaatattcct aatatgcctc agcgaatcgc cacggatacc tctcaaaagg tggcgattcg
    21901 ttatggtgag acgattaaaa aatatatgga aatagaagtt aaagacccgc agacacttgt
    21961 attcatacca ttgactctcg ctgcttggct tcgatacctt attggcattg atgatcaagg
    22021 aaaaccattc atcccgagtc cagacccact attgacagac cttcagcata agctttccga
    22081 tattcaactg ggtacgcaag atacatcaca tattcatgag aaaatggctc ctattttgtc
    22141 aaataaagaa atttttggtg tagatcttta ccaagcagag cttggcagaa aaatagaaga
    22201 aatgttcatc aagatggtag caggaccaaa tgccgtacga aaaacattac aggattactt
    22261 acaagaacat ggaggaaatt tatcatggaa atgactttta gatggtacgg atcacaggaa
    22321 gaaaagatta ccttagatga aatcagacag attcctgcgg tcaaagggat tgtaggcaca
    22381 ttgatggata taccagtagg agaggtatgg cctagggaga ggatcaaaga actaaaagaa
    22441 gaaattgagt ctcgtgggtt aacactaaaa gtaattgaaa gcgtcaatgt gcatgatgcc
    22501 attaaaattg gattaccttc ccgtgagcag tatatcgaaa actataagca gacaatccga
    22561 aacttggcag aatatggaat agaagtcatc tgctataatt ttatgcctgt atttgactgg
    22621 gtgaaatctg accttgacta ccgcttagaa gacggctcat ccacgttagc ttttatatct
    22681 gatgatattc cagatgatcc aagagaaatc gtcgcgcgca tcgaacattc cagcaatgaa
    22741 tttggattgc cgggatggga acctgagcgc ttagctccta tcaaatcctt gcttgaagcc
    22801 tatgcatcag tagacgaaga aaaacttcga gaaaattttg cctattttct ccaatcaatc
    22861 atcccaacat gtgaagaggt aggggtcaaa atggctgtac atccagatga tccgccatac
    22921 tcgatttttg gattagctcg aatcgtaaag aatcgagaag atttagattg gttgtgtcgc
    22981 atagtagaca gcccttataa cggaatcact ctttgtacag ggagtattgc agaagatcca
    23041 gaaaatgatg tatatgggat tttagcagaa ttttgccaaa gagatcgaat cccatttgca
    23101 catgttcgaa atattaaatt tttagctaat cgagatttct atgaggcacc acataaatcc
    23161 gaatacggtt cattagacat gtaccgcata ctaaaaacaa tgtatgacat cggatttaac
    23221 ggatacatcc gtcctgatca tggaagaatg atctggaatg agacaggaag accaggatac
    23281 ggcttatatg atcgagcatt aggtgctgtt tatctaaatg gattatggga agcaatcgaa
    23341 aaaggaaaca aaagtaaaga taattagtga aaaaaactgt aattttatta tgtaaataag
    23401 aaggatgttc aaattcttga tacataaatc cggaggttgt taataagcat tcggatttat
    23461 gtatcttatt tggtctagga agtaacttga ttttcttttt tcgattgatc catgagtgct
    23521 tcttctttta attcaaagat atattctgag atcctcataa tcactttttt ccagtcttct
    23581 ggtgtgatga ttccttttaa aatatagatt tttttgatat gagaaggcaa ttgtttcaaa
    23641 gggcagtcgc tgataacgat gttgcagttc tccataaaat cattttgtat tttgatcgat
    23701 tcatttgaaa aaatttgttc tatcttaacg atcagatctt tactgatata aaaatcacgc
    23761 gtatagttca caccaatcac aattcgcggc tgttttttgt agcgatcata caaatgtact
    23821 aggtcttcaa ccatccattg cacattttcc ttttctaaaa taactggtaa caagtgttga
    23881 ttttgttctc tgaaatccat ataaaattgt tcaatggcgg tttggacttc tttcaatacg
    23941 ctatgttctt gataaagcat gaaagtagga aggggcgtat ttggttgatt gaagttaaga
    24001 aatccattat aaagtttatt tcgtgcgaat gccaatgagt aaagaatctt ttctttttca
    24061 ggtataaaca aatcaaatac agtacaaagg gactccacca tttctcttga ataaagaaca
    24121 tgaggaacgt ttgctttttt taaaagtttg tattgctcca agcttgtttc ttccgattcg
    24181 attttcgtga tagaaagtcg agctaaaata ttcactaaga tgcgttgttc gcgacaaatt
    24241 ggcagattag gtcgcaaaat atctacagag agatcaataa aaaagtcaat atattcatac
    24301 tctgtgaatt ctttttgtac gtctttcaca gaagttgcag gaaaattctc tttacatatt
    24361 tttaatagaa aatataattt atctatcata ccgctattta gtcggtcaag tacttctttt
    24421 ttaaaaaaag tattcatcat aaaagccact acttgcggat cttcatcata aaattctgta
    24481 gcagtacttg aaaagatgtt ccaataaata tctaatgctg catattgaat ttgtacctct
    24541 tttccagaaa aagactttct gccattatta gaaaaggaga tagacaaacc gtactatgct
    24601 aaaaatgcat taatcttttt cattttcgta tacaaataag aggcactata gtttgtttgc
    24661 tgactgaaac tgataatcga atttgtctga cagctgaaca aagaagtcaa gatctgataa
    24721 ctgactgatt cgttgcagta tcttccaaat agacgataat agcagtaagc cggatcaatt
    24781 ccttcaaaat tcaactttaa aaaaggtttt tgcttatcaa tatgcagttc tgttagattg
    24841 agacgctcaa agtcttgttc taattctttg atgtatagta aaaaatttga ttcagacata
    24901 tggaaatgat ctgctaaata ttgtgtagta ataaagaaac gatgttcaga taggaaaaga
    24961 aaaatatcta attttgtatt gctttttttc ttcaagataa acgttttaat cgcttcttga
    25021 gtttgcatga aagaggctcc tttttactta aattgttaaa acttgaaaat attactgttt
    25081 ttttcataaa tttagacaaa aaaacagtaa acatataggt agaatctcta ctatcttatt
    25141 tcttgcatac aaaaaaatca aggagtgaga gagttatgag atattcaacc atcttaatat
    25201 caacatttgc agccttaagc ttatcgctta ctataaatca gacagtccac acagaggaga
    25261 cagaaacagc caaatggaca gaaaccaagt gggccaacgt caatcgaatt acctttcagg
    25321 atgaattttc atccttcaat tcaggagtcg caaaattaag aaaaggacaa acagcgacca
    25381 tcaaagcaaa aattgactat tcgggagact tagcacctat actacaatca gctgttacat
    25441 ttgagaatgt tgatcccact ttgtcgattg gctatgacga gaacactttg actatccaac
    25501 acaagcaagc gatatttacc ttcaccgtta cattaaatca ggacttgtta aaaccagcgc
    25561 tttttactgt caaggtatca gatggactac cgaacgatca tcatttaacg ccgtatagtc
    25621 agcggcagac aattgagcaa gattcagcca tcgactcagg aggagatctt gttgaagaac
    25681 caacagataa accagaaaat gaaaataagc cagaagtacc gcctacagaa aatccagacg
    25741 gagaacagaa accggaaata gaacctggag aagaacccga tacagaaact caaccagagc
    25801 cagacaataa atcaaaacct gaaataaccc ctggagaaaa accagatgta actccagaac
    25861 cagatacgga ttctggaaac caaacagtac cggaaacaaa tccagacaca gataatgaaa
    25921 ctgaaaatcc agaaaaacca gaggtagatc cagaagaaaa accagatgtg actccagaac
    25981 cagatacgga cgcaagagac caaggaatac cagaaaaaat aaacaaaaaa acaattcaag
    26041 aggatggaaa aaaagagagt aaaaaatcaa atctagcaat tctaaaaata aatgaagagc
    26101 agctgaataa aaaatcacga atatttgata gcgcccaatc agctgaaacc ttaaaaagta
    26161 gcaaggatac aacctttgct gtcctgaaac gaaaaataaa cagctaccaa aatccggaga
    26221 gtcacaaaac aaagttatac tgtggagcgg aatcattcta ttaagtatag caacaatgct
    26281 ttctgcaaaa agatttaaac aaaacagatc tctctaacat ttgaataatg tctgtgaacg
    26341 catttttcaa ataaaaagaa atatccagaa aatgacccca aaataccaga ttgaaatctg
    26401 atatttgggg tcgttcatac tttatctttc ttcatattta ttttaaggga tatctgtttc
    26461 ttttggaaga tggttcggga tctttttcac tttcaataca tctaaaaaga aggtaaagat
    26521 cggaatgccg acaatcaagc cccaaacgcc aaagaaccgt tcgctaacaa gtaagaccac
    26581 aaatgtataa aaaatcggca gttctgtttt gctggacatc aacttcggat tcagcacata
    26641 agactcaatt agatggacaa tcaaaatcgt aatcaggata taaacaacat ctcggatgcc
    26701 tccttgggaa taagctatga aagatagagg aatacaagaa atgataacac ctgctactgg
    26761 gatcagactt aaaatgaaaa tcatgatcgc taaactcagc agctgatgaa agccaaatac
    26821 agccaaggcg attgtagtga gcaacgtatt taaaagagcg acaacaaatt gagcttctaa
    26881 taccaaacca aatgtattga caaacttatc ggcaaaatag taaatatctt gaaagaacca
    26941 agaaaattca ctttttaaaa acaatcttga gaatacaatt gtttttttct tttcaatcat
    27001 aaaaaagaaa cttaagatga atgacatagc aaacgccact gccatttttc ctatatcctg
    27061 taaatagcca agcgcaatcg aagcgccatt ttgaagctgt tcaaaaaaat cgtttcgctc
    27121 aatataagta tggatatatt gtaaaacagg atctgcatct tttggctgat gctcgtaaaa
    27181 attaataacg gactggatca tgtcaaatgt ttgatgaata agcatcggga tatactttgt
    27241 gaatgccaga tagataaggt aaacgatcag tgtataaatc atgatagcta aaacacctgt
    27301 agggattcgg acaaatcgct gaatgatttg aacaagatga atcatcaaat aagtaaagat
    27361 aaatgtgagc aaaatggttg taatcatact tctaactaag aaaagaacaa aaacgacaaa
    27421 taataaaaca gtgagacggc gtattttttc attcgccaaa aaacgctgat aaacggtcaa
    27481 atcgacaacc tccaaataac aaaaaataaa cacgttattc attatatgat ggaatatgaa
    27541 aataagaaag agcaaaaaga aaaaccgcta aatgacgtta tcttatgagt tggttttcct
    27601 cataaaatcg ttcatctagc agtttcagcc ctttttctgg tcttgatgaa aattatctag
    27661 catttttcgg gtcagatgtt gcagtgtatc caattcttcc tgttcaagtg gaagataaga
    27721 cttgatcttt tgtggaatac cttctgcttg tttttgcaac gcagcacctt gagcagtcag
    27781 cgtaacattt acgattcttt catcacccgt ttcacgctga cgattaatat aatttttttc
    27841 tgctaacttt tttagtaagg gagtcagcgt accagaatcc agacacaaat catttcctag
    27901 ctctttcact gaagtctttt tcttttccca taaaactaac atcacaagat actgggtata
    27961 ggtaagattc agcggcttga ggaggggagt gtagtgtcta atgatttctt tagaggcggc
    28021 atataaagga aaacatactt gattaactaa atatagatct tccatttttc cacctccgct
    28081 gttttactat agtgtatcat agcggattta cacaaaaaag tctattcact aactgctttc
    28141 agagtaactt ctatatttcc agctgtagct tttgaatacg gacacacttt atgcgctgcc
    28201 tctaataatt cttgcgtttc ttccagagaa agaccttcga tagatccttc aatctctaca
    28261 cctaagacaa agctcgtttc actttctgaa taaagggaaa cttgtgcact gacagtagaa
    28321 gccccagaga tatttttttg ctgtttgatc aattctaatg cactgttaaa acatgcactg
    28381 aaaccagctg caaacaattg ttcagggttg gttgcatttt cgacgcgttt accaggagct
    28441 gcaatattca attcgaatgt acgatcggga ttatgcactt ctccagagcg tccgcctgtg
    28501 ttgatcattt tcgtagaata catttttttc ataaagttac cacctttaat tatattttat
    28561 acaattgaat tttacacaat ataattgtgg aaagcaaaga aatggattgg cataagataa
    28621 ataagagaaa gcacatgaaa cagacgcgct ttctcgaata gcaaacatat acaaaaaata
    28681 tcagagacaa aaaataatct catcataaac attacatata tttctcaaaa agttgttttc
    28741 tttcttcaaa aattacttca cgatggacct gatgaagcat ccataaataa ccaaaaggat
    28801 ctctgaacat tgagttagtc acaccaaagt ccatcatttc tgtcatttct tgaatctcta
    28861 cacagccatt tcgtaatgct ttattatgtg tgtcctcgat atcagagacg atgatattga
    28921 accagatcgt atttggatgt tcagcagtag gagcagtcaa accaagagac gtgttttcat
    28981 ccagcatatg gaatctcgta ccatacaagg taaaaatgac ttcattattg cctctagggt
    29041 aatctgttgc ctcaatcagt tgtatttcat caaagattgt ttgatacagt tctagtgctt
    29101 tcaaactatc atttaataca aaatcgattt ccgttccttt atgcataaag atctcctctc
    29161 cttttcagtc gaacagttac tagattcttt tattatacca gctaaagaaa acgcattcaa
    29221 aaaaatagcg gatttactta ccaactcatt cgattggatg ataagtaaat ccgcgtccca
    29281 ttacttctgc tacgctgctg acaatgacaa aggcacttgg atcgatttct tctatcaatg
    29341 gtttcattcg ggaaaattca tgatcagtca caacgatcaa taaaacctct tttgactttc
    29401 gattataccc gccttttgcc tctagcaggg taaggccacg tccaatctca gcacttaagc
    29461 gaaggcggat gtcttccaaa taatgttcac tcatgaccat aacagatttc tttcgattga
    29521 tacctgtttc gatataagtc atgacaattg aagtgattgc aatagataaa atagcataaa
    29581 gaaactcttc tattccaaaa ataaacagat taagagaaac aacgaatgcg tctgtaaaaa
    29641 ataagccaat cgaagtattc aagtggaaat attttttaaa aatgagggga gggatcgtcg
    29701 taccgccgct agaagagttg tttttatata aaatcgcaac tcctaaagca aaaatcgcac
    29761 ttccaaaaat gacagacaac aaccgatctg aagtaatcat tgtttctgga actattgcaa
    29821 tgattaaagg aaaaaccaag cttccgaaaa gtactttaaa aaagggtttt ttacctaaaa
    29881 atagaagagc tagtaccaac ataacgatat tcaacactaa aataactata gctcggtcaa
    29941 agcctaaagc agcttccagt aatattccta gaccgctgac acctccagca gcaatatgat
    30001 gaggccctaa aaacatattg atagcgactc ctaatatgaa gagggcaaaa ataatcttaa
    30061 tgtatgtcca tataaattgt ctcgtttctt tcatttattc acttccttaa ttcattaata
    30121 atactcttat cttattataa cttacttttc accttaagtt aactttaatt aataaaaaaa
    30181 ttaggctagt ctaaattatt atgtttcatt cttctagaat atacttctac gccaaaaact
    30241 gttaaaaaac ttttacttta gaaaattgga gaaattgatc gcttaagata aattcaggac
    30301 actaaatagt acaggaagta gactaaaact tttaaaagtt ttaagtctat ctatttggca
    30361 agtttaaaaa ataaaaattc ggtatcaaaa aactgttacc gataacattt ttgaaagcgt
    30421 tgtcttttgc ttctctatca cttatagtga tgacgtcata ttaaaacaca aggaggaaat
    30481 caatggatac agctgcaatt tatcatcgac cggaaagtga atatgcattt ctatatacga
    30541 atacaagatt tcgtattcgg cttcgtacta ggaaaaatga tatcaaaaaa gtatatgtgc
    30601 tatgtggaga tccatatacc ataacaactg aaaaatggta tcaaaaacaa cgaccaatga
    30661 aaaaatgtct aagtaccaat gttcatgatt attgggaaat tgaagtgacg agcgaaacaa
    30721 gtcgcttaca gtatgcgttc catgttgttg gggaagataa cacggactgt ttttacggtg
    30781 atcaaggaat ttttccttat cgagaaaatg tgattactga accaaatttt tattttcgaa
    30841 taccttattt tcatcaaatc gatcgattca ctattccaga atgggtaaaa gaaacagtat
    30901 ggtatcaaat ttttcccgaa agatttgcaa acggggacaa agcaaatgac cccgaacaca
    30961 ctttaccttg gggaagtaaa gatccagacc gagaagactt tttcggggga gatttgcaag
    31021 gtgtgatgga tcatttggat tacttgacgg accttggcat caatggcatc tatttttgtc
    31081 ccatatttaa agccacatcc aatcataaat acgatacgat tgattattat gaggtggatc
    31141 ccgcttttgg cgataaaaaa cttttaaaaa acttgattga tgaagcacat aaaagaggga
    31201 tacgtatcat gttcgatgct gtattcaatc atatgggtgt ccattcacca cagtggcaag
    31261 acgttctcaa aaacggagaa aaatcgatct ataaagactg gttccacatc cgttttttcc
    31321 cagtagattc ttatcagatg actgacttac cagaaactgc tgaaaatatc ccatatgata
    31381 cttttgcttt tactccattc atgccgaaac taaatacagc aaatccagaa gtgcaaaaat
    31441 atttgctgga tatcgcaact tattggataa aagaattcga tattgatgga tggcgtcttg
    31501 atgttgctaa tgaagtcgat catcattttt ggaaaaaatt cagagaagca gttacagaaa
    31561 tcaaaccaga catctatatc cttggagaga tttggcattc ctctcaagct tggctgcaag
    31621 gggatgaatt ccatgcagtg atgaattatg catttacaga ttcgattaaa gattattttg
    31681 caaaaaagaa aatcacagct tcacaaatgg tcagtggaat gaatcatcag caaatgcttt
    31741 acagagatca ggtgaacgaa ggaacattca acttattaga ttctcatgat actgccagga
    31801 tcttgaccct ttgccaaggt aacaaagaat tgatgaagtc tgtgatggcc tttatgtttc
    31861 ttcaaaaagg gtctccttgt atctattacg ggacagaaat agggatgact ggtgaagatg
    31921 acccggattg ccgcaaatgt atgatatggg agaaggagga acaagatcta gagctattcg
    31981 gttttataaa agaacttgtt tctctaagga aacagttgtc taagattatt tctgaaggtt
    32041 ctactcagtg gctaatagta aatgatcgtg aagataagct ctatttcaca cggaaactag
    32101 agggacagat catctatgtt tactttaatc agtcaaaaga accttgggta gtagaacagg
    32161 aaaatgaggt gattcttagt caaaattgtc agttgttaga agacgggaaa gcagagatac
    32221 gacaatacgg atttttgatc atgtgttgaa aactgttacc ggtaacaaca agaaagcgtt
    32281 tgcaaatgaa gatttgtgcc cattataata agggtgtaac agcacgttga atacaaagga
    32341 ggaaatgaag atgaaaaaaa gaagtgtgaa acagttgggt ttagggttaa tctctttagg
    32401 aatcttaggc ggattagcgg cttgtggcaa tggtaactct tcagcagaag gggaagccga
    32461 tgaaggaaaa acgttaacag tttccgttga ttctggatat aaagattata taaacgaaat
    32521 aaaaaacact ttcgaaaaag aaaacgatgt gaaaatcaag ctagtagaaa aggacatgtt
    32581 cgatcagttg gaatcattag cgttagatgg gcctgctgga aagggacctg acgttatgat
    32641 ggcagcatat gaccggatcg gtgcgttagg acagcaagga catctggcgg aagtaaaact
    32701 gggaaatgaa gcagcttacg atgaaacaga caaagcccaa gtgacttatg atggaaaaat
    32761 ctacggagaa cctgcagtaa tcgagaccct tgttttgtac tataacaaag atttagtcga
    32821 tacagcacca tcaacgttta aagatttgga gaatctatcc aaagacagtc gttttgcttt
    32881 tgagtcagaa gcaggaaaaa atacaggatt tttagctaaa tggactgact tttattattc
    32941 ctatggttta attgcaggtt acggtggcta tgtatttggt gatgatggca caaatccttc
    33001 agatatcggt ttgaataatg caggtgctgt agaaggaatc tcttatgcaa cagattggtt
    33061 caaaaatgtt tggccaaagg gaatgcaaga cataaaaagt gcaggagact tcgccagcca
    33121 gcaattcatg tccaataaaa ctgcagcaat cattgacggt ccatggcaag cgcaaacata
    33181 caaagaaaac aatatcaatt atggtgtagc caaaattcct actctaaata atggacagcc
    33241 ttatcaaccg tttggcggag gaaaaggatg ggtagtcagc aattatgcta aaaacaaaga
    33301 cctctctcaa aaatggcttg attatgtaac gaatcaggaa aatcaagaaa aattctttga
    33361 aatggtaaat gaaatccctg caaaccaaca agctagggaa acagcaaagg ctaaaaacga
    33421 tgaattaaca acagctgtga ttgaacaata tgaaacagct caagcgatgc caaacatccc
    33481 agaaatgggc gaagtttgga caggtgcaga aaacttgatg ttcgatgcag catcaggttc
    33541 aaaaacacca aaagaatccg cagatgaagc agtaaaaaca atcagtgaag ccatagaaca
    33601 aaaatactga ttaaaatgat aaccgtccat ttttataaaa aatggaacag gtgcttcaga
    33661 taaaagtggc aagagcgaga tggaaaatta tcttgctctt gttgccatta tcttaaaagc
    33721 agtttgcggt ttagcaagtt tagagggggc attcagatgc agcaagataa aacaagcaat
    33781 atcaacgaaa aaaaaatcac gctttgttca cttattccag ggatggggca gtttgtaaat
    33841 ggccaagctt ttaaaggtat cgtttttttc gccatattcg tcctattcat tggtcagatg
    33901 cttctgggcg gatttcatgc attggtagga ttggttactt tgggaagtat accaatggaa
    33961 gatcattcat tatttatttt gattgaaggc actttgcaat tcatcattac aatcattttc
    34021 ttgatttttt acggtttgaa tcttttagac gcttatcgag tagcgaagat gcgtcaagag
    34081 ggcaaaaaaa tcaatcggac gatgaaggaa gtcatacata atataggtga tgaaggtttt
    34141 ccttatctat tgacacttcc cgcttatctt ctcatgattt ttacgatcat tttcccagtc
    34201 ctagttacat tgttcactgc atttactaat tatgacttca atcatattcc accagccagt
    34261 ttaattgatt gggtaggggc taaaaacttt tttagtatct tctttttaag ctcatatcgt
    34321 aatacttttt ttgcagtctt ttcgtggacc gtgatttgga ctttatgtgc aacaactttg
    34381 caaatcaccc ttggtattct cacagcggtt gttgctcacc agaaatttat taaattcaaa
    34441 cgtattttcg gtatcatttt cttattacca tgggcggtcc cagcttttat tactatcatg
    34501 agtttttcga atatattcaa cgatagcgta ggtgccatca atactcaagt gattcctttc
    34561 ataaaccagc ttccttttgt agatatcagt gcaatctctt ggaaaacgga cccgaactgg
    34621 acgaaagtag caattatctt agtgcagggc tggttaggat ttccctatat ctatgtgatg
    34681 gttacaggaa tcttacaatc gatttcagaa gacttatatg aagcagcaaa aatcgacgga
    34741 gcaaatgcat ggcagcgctt ttcaaacatc acgcttcctg ctgtcttcct agtggcagcg
    34801 ccaacattta ttacacagta tacggggaat ttcaataatt tctccatgat ctatctgttt
    34861 aacaatggcg gtcccggaag cgtaggcgga ggagctggtt ctactgatat tcttatttcc
    34921 tggatctata aacttacgac tggaacttct ccgcagtatt ctatggcttc agcaatcacg
    34981 ttgattatct ccgtcatcgt tatctgtgtg tcattgctgg tatttaaaaa gacaaatgcg
    35041 ttcaatatgg gggattaaca atgaaaaaat ttcattcgag tgctcgattc caaaaacgac
    35101 tttctcactt ttttacttac ttttttcttt taatactgtc agtcattatc atctatccgc
    35161 ttttgatcac agcaagtact gccttcaagt caggaaatat tgcagctttt agtttagatc
    35221 tttcaagtga ctggacttta ggaaacttta ctcggctatt cagtgaaaca ctttacggga
    35281 cttggtataa aaatacattg atcatttctg tcctaacaat gatcgtacaa gtgactgtag
    35341 taactttggc gggctatact tatagtcgct atcgttttat cggccgcaaa tcaagtttga
    35401 tgttcttttt agtgattcag atggtaccga ctatggcagc attgactgcc ttttatgtca
    35461 tggctttctt attagaagcg ctcgataagt actggttctt gacaatgatc tatataggcg
    35521 gtggaattcc aatgaatact tggctgatga aaggatactt tgacactgta ccaatagatt
    35581 tagatgaatc tgctaaactt gatggggcag ggcatttcag gatttttttc cagattgtat
    35641 taccgcttgt caaaccgatg ctcgccgttc aagcattatg ggcttttatg ggaccttttg
    35701 gggatttcat gttagctaag ttcctgcttc gaacacctga aaatcagact gttgctgtcg
    35761 gcttacaaac atttatttct gatgtgacaa accaaagagt ctctcttttt gctgctgggg
    35821 caattttgat tgcactaccg atttgtctat tattcttctt tttacaaaag aactttgtta
    35881 ccggcctgac atctggcgga acaaaaggat aggagcagag tatcatgcaa acatttccgt
    35941 taaactattt ttccgcatta cgtacgccaa ctcaagtgtt tgcgggacgc aaactattat
    36001 catggcctaa atttttcttg atatttgtat ttttagtttc cttgatggtc atgcctgtga
    36061 ctctttttta tgccaatcag atccaagcga ttccattaga acaatttcta tccgttcatt
    36121 cgctgatcga tgaacaagga acccaaaaat tttctgaact tgaattatct gaaactgggt
    36181 tacaagcatc gcaacaaacg atagctgtga cccctgaaat tttggtaggt gtgtctttat
    36241 ctgagaaaca acaatccgat catggaactt ttattgattt tgagaaggaa caatgggtga
    36301 tccaacaaaa ggataaatct ggtatacgcc gctatacgat gaattatagc ccatctttcc
    36361 aaccagattc tgtacgtacg cccgaagatt tccaacgatt tttagaaaga gaattttatg
    36421 ccagtaatcg tccaacaatc attttatctt atagtttaag tcttggtctt gtcctatttg
    36481 tcatgacgag tctcatttta ttcggggctt cctttttctt gtggatgaca agaaaaagcc
    36541 aactttcatc cattcataca ttcaaagaga gtgcaaattt gatgctgaat gttatgggaa
    36601 taggttccat ggcagcagca gttgtagggt ttatccactt tgactttatc ttgatgctaa
    36661 gtgtccaaac aacgataact gtcttgctgc ttttatgggt ttttgtcaaa acaagattca
    36721 aagataagcg tgtcgaatga caagtttaag cgatttatgc gacaatgaat gtgaaaaaaa
    36781 tgaaaaataa agtagttttt gaaaaatttc tgaaaaaatt aaacttctta gttgattctt
    36841 ttctttttta gtattaacgt aatagggtag tttttttaag gaggaaaatc atgttagaga
    36901 aaactttata caatcaatta ttttcacgtt ctttctcgct ccctgtcgaa gtaaattatt
    36961 gggacggtac aacgaaacaa tacggagata cggacactcc tccccaaatc aaaatcaata
    37021 tccatgaaga aatcccaatg aaagagatta caagtaacgc ttctttggca ctaggagaag
    37081 cctatatgga tcatcgaatc gagatcgagg gaagtatcca agcattgatc aacgatgctt
    37141 atcagcaagc aaacagcttt ttacgaggaa aagattatct aaaatggctg ccaaagaaag
    37201 aaaaacatac gaaacaaaaa aacaaagaag atatccatgc gcattatgac ttaggtaacg
    37261 acttttataa actttggcta gatccaactt tgacttattc ttgtgcttat ttcaatacac
    37321 ctgaagatac gttggaacaa gcacaaatca ataaagtcca tcatatctta gacaaactct
    37381 ttatcaaaga aggcgaaacg ttgcttgata tcggttgtgg ctggggaaca ttgatgttca
    37441 ctgctaccaa agagtataat gtcaaggcaa ctgggatcac actaagtgaa gaacaatacg
    37501 atttgattac caaaagaata aaagaagaac atttagaaga taaatgccgt gtattattaa
    37561 tggattaccg cgaactaaaa ggcgaaacgt ttgatcatat cacaagtgta ggtatgttcg
    37621 aacatgtagg ttctgaaaat cttgaaggtt atttcaaagt ggtaaaagat ttattgaaac
    37681 caaaaggaac agctttgatc catggaatca gccgacaaca aggcggtgcg acaaatgctt
    37741 ggatcaataa atatattttc cctggcggtt atgtccctgg tgttactgaa ttagttgata
    37801 atattacaaa aaacgatttg caactgattg atttggaaag cttacgtcgt gactaccaat
    37861 tgacattaga acattggaca aagaattttc atcaagtcca agatcaagtc acgaaagaaa
    37921 tgggtgattc cttctatcga atgtgggatc tatatttaca agcttgtgca gcttcatttg
    37981 aatcaagtaa tatcgatgtg attcaatatt tgcttgttca acctggaaac aatgacatcc
    38041 caatgcatcg tgcataattg aggcaaaagt actgtttaaa gactatttaa aaagaagcta
    38101 agttttatga tgctccagaa gtgaactttt ttgtctaact tctaggattg tctctaaagc
    38161 ttagtttctt tttctttata ttttcataat aaaagtttgg ttctttaatt tttaaacatg
    38221 acagaaaatt ttttcttcgt tatacttgta atagaatact attttataac aaaggggatc
    38281 gaatcaatga aaaaaactgt tatttatact agtttatttg cagctttgtt tttagctgct
    38341 tgtcaatcaa ataccaatca aggcacatct gggaatacgt cttccagtag cgaacagcgc
    38401 tcttcacagg tatcggactc ctcaacaaaa gcaagcacat cttcgtctag ccagacaaaa
    38461 agttctagtg aagcaagtac tcagtcagat atcaaagtgt ctgcagctcg tgcgatcgaa
    38521 ttgttccaag ataaataccc agatactgca attactagtt tggaattaga tagtgattgg
    38581 ggatcttact tctacaagat agaaggtgtc gatgatcaaa aagaatacga agcaagaatt
    38641 gatgctcaaa atgaaaaaat ggagacagag aatccagaaa ctctagatcg agatgaacaa
    38701 aatggtcaaa agaaaaaaga agatggtctg gatgttgata aattgatcac gattgaggaa
    38761 gcagcaaaaa tcgccgtcga caaagtagga agcggtacgg caacagattg ggatttggat
    38821 aaagatttag gtactactta ttgggaagtc aaagtaaaag acggcaatca aagtacatca
    38881 gtcaagatca atagccaaac aggcgaagta ctgtcaactg aacaagatga ttaagaattt
    38941 cttcggaaaa caagagttga tttttctttt agtcatgata cactagacaa aataacttgt
    39001 ttgaaggagc gatttacttg agtttagaaa cgacctttgc caatcatatc tttgccaatc
    39061 ctttgatgaa tgcatctggt gtccactgca tgactaccca ggaattagat gaactggctc
    39121 attcagaagc aggagcattt atcactaaga gctgtacgat caatgaacga aaaggaaatc
    39181 ccgaaccacg ctattttgat gttcctttag ggagtatcaa ttctatggga cttccaaact
    39241 taggtttttc ttattatcta gagtatgctc ttgcgtatga aaaagtgcag gaaaaccaaa
    39301 atcaaccgtt atttttttcc attgccggga tgagtgtcca ggaaaacttg gaaatgcttg
    39361 agaaaataga aaaaagtggg tttaatggga tcactgaatt aaatttatct tgtcccaatg
    39421 tgcctggaaa accacaacta gcttacgatt ttgaggccac ttatgaaaca ctgaaagaag
    39481 tattcagcat cttttctaag ccgctaggaa tcaaattgcc tccttatttt gattttgctc
    39541 attttgatca gatggctgat atcttgaatc agtttccatt gacctatgtc aatgctatca
    39601 acagtgtggg caatggtttg tatatcgata cagaacaaga agcagtagtc atcaaaccaa
    39661 aagaagggtt cggcggcatt ggcggagagt atatcaagcc gactgctttg gcgaatgttc
    39721 gcgcttttta tacacgtttg aaaccagaaa tccaaatcat tggtacaggt gggattcgga
    39781 caggacaaga tgcatttgaa catctgctat gtggcgcaag catgttacag attggtaccg
    39841 agcttcataa agaagggccg gaaatttttt ctagaatcat aaaagaatta acgcagatta
    39901 tgtcagaaaa aggatatacg tcaattgacg aatttaaagg caaattacgc accatttcat
    39961 agcaaagaga cgaaggtcat gattgatctt cgtctttttt tataaaaaac actcgtctgt
    40021 tcattcctgt gcaagcgtac tcattgtatg ttagacgaac ttgtgggaaa ataacagagg
    40081 caaaaaggag gataatatga atgatgcaac agaattagca aaagagctta aagaaaaaga
    40141 atttagtttt caagaactag ttacggatat acagaaaaaa ataaagaagc aaaatcatga
    40201 attgaatgcg tttgtcgcgc ttgaaccatt cgagagtaat tcccacgagc tattgattcc
    40261 ccagtcagaa aaagggccat tggctggtat cccatttcct ttaaaaatgc tcggtcaaga
    40321 aaaaaaggga tggctagcta cttcaggatc tcgtttattt gaaacacacc gagcttctca
    40381 tacatctaat tatgtgcggc aagcagaagc gataggtcta gttccttttg gacaaaccaa
    40441 tgcgccagag tttggtttca aaaatattac agacccagtc atctatggcc cagcaagaaa
    40501 cccttggaac cttgaatgta caccgggcgg atcaagtgga ggagctgctg ctgcagtttc
    40561 atcaggaatc gttcctttag ctggtgctag tgatggcggt ggttctatta gaatacccgc
    40621 ttcgttttgc ggattgattg ggctgaaacc ttcgcgaggg acgatgccag ttggtccata
    40681 tgcttggaga ggatggcaag gagctgctat tgatttcggc ttgacagttt ctatgagaga
    40741 cacggaggct ttattttatg ggatgagaag tatccattcc ggtgcgccat atcaagtatc
    40801 gccagttgag tggcaaacac atccaagaaa aaaacggttg aagatagctt tttgtgttga
    40861 ttcaccgatc cactcacaga ttagtgaaga ggcagtactt gctgtaaaaa aagctgtaga
    40921 tttccttgga aaagaagggc atgatttgac agagattcct tacccactag atggtcgtaa
    40981 actgatcacg tcttattatc agatgaatgg cgcagaaaca gcagcaatga tccgctcgat
    41041 tgaaacaggc atccagcgag ctgtcagaaa agaagaactt gaacccattt cttggacttt
    41101 gttccaatat ggtcagaagc tctctgccgc tacttacatc gattctctgc atgtatggga
    41161 tgaagcagca attgtcatgg aaaacctaca tcaagaatac gatctattcc tttcaccaac
    41221 gactgcattt accgccccta aaatcagcga agatttgcaa agtgatgcga taagagcaca
    41281 gatggaacac atcagtgatt gttctgaagt agaaggttta gacgttgttt cttccatgtt
    41341 tgaggagagc ttgaagatca caccttatac acagttggct aatctgactg gacaaccagc
    41401 aatcagcttg cctactcatt tgacaaaaga aaacatgcct ctaggaatcc aatttatggc
    41461 tgccagagga agagaagatt tgctatttca aatcggctat ctatttgaag caaatcatca
    41521 gttccattta ccaaatccat ggaaatagca gaaacaagga gaagaagaat gaagaaaaaa
    41581 agattgtttg ctctaataac tagtgccttt tttattttaa gcgcttgcgg tacagctgcc
    41641 gctaatcagg aagataacag ctggagtaat gtagaaaaaa agaaagaatt agtagtagcg
    41701 acttctggca cactgtttcc cgcatcttat tataatgatc aaaatgaatt agttggttat
    41761 gatgtagatt tggcaaaaga ggtggctaaa cggttaaatg tcaaaatctc ctttaaagaa
    41821 tacaacgtgg atggacaaat cacttctgtt tcaaaaagag aatcagattt tgctgcgaac
    41881 gattttggta tcacaaaaga aagagaaaaa aaattctccc tttcagagac tttcaaatat
    41941 tcatttgaca gtatgatcgt acgaaaaaaa gatgattcag gaatccactc acttgaagat
    42001 cttaaaggga aaaaagcagc tggcgaaccc aatactagct atatgcgttt agcggaaaaa
    42061 cacggagcta aattagtcac atatgacaat gccacgaatg atcagtattt aagcgatgta
    42121 gcaaatggtc gaacagatgt tattctaaat gattattatc tgcagaaaat ggccgtatct
    42181 gctttaccag atatccctgt aaaaatactg gagaacgttt atttcaatga aaacgaaagt
    42241 ggttttttat tgaaagaagg aaatgatgct ctgaaaaaga aaatcgatgg cgtattaaaa
    42301 gagatgaaag aagatgggac gacaaagaaa atatctgaaa aatattttca aactgatgtt
    42361 tcagtcaaac cgaaagaaac gatggctgag tcggtgagtg agtgatgtac tttcctctaa
    42421 ttgatttttc cctcatgtgg acttcacttc ctttcgtact gcaaggcttg gtatacacat
    42481 tagggattgg cttcgtgtcg tttcttttag gaaatctggt agggttgctt ttgacagttt
    42541 taggtctttt ggattggctg cctctgaatg tatttattcg tttttattta tcgttcttta
    42601 gaggcattcc cgcactagtc ctgctgtttc tgttatattt tgggttacct tatcaattaa
    42661 gtgccttaac ggcttcagtc atctgcttta cgattaccag cagtgcattt attggtgaaa
    42721 tctatcgagg atcactagca ggcgtttctt caggtcagtg ggacgctggt ttagcttctg
    42781 gtttttcttt ctttggggta ttgaaatata tcgttttgcc gcaagctttt cgaatctcag
    42841 taccggcact cagtaacgta gctatggatc tagtgaaagg tacttcgtta gcagcaacaa
    42901 tcacagtgcc agaaatattt caaaaagcaa agatcatagg cggtcggaca ttcgattatt
    42961 tttctctcta tattttagtt gcactgattt attgggtcat ttgtatcggg atcgaaaaag
    43021 tgcaacagta tttagaaaaa cgttctatgc atcagtcaat ctgaaaaata gaaatggtgc
    43081 tagcgtggct ggcaccattt ctattttttg tttcttgtat attctgccta gtattttaaa
    43141 accatttcat gtaaaatgta aatcgaaaat atgttcggag gtagaaaaca tgaagacccc
    43201 gctaaccatc gaaatagaat cctcgttata ccaatattgc atcgagcaag gcggcttggt
    43261 tgtagaagaa gtcacgatgc ctgatgacca aggaattgta gatacgctta gctgcttgac
    43321 aaaatttgat ggaagccgag aatggcgatg ctatgagctg aaagtgacaa aagcagattt
    43381 tcgctctaca gccaaactgt catttgttgg acattataat tattttgttt taccaagtaa
    43441 actatatgaa gaagtaaaaa ctgaaatccc tacaggaata ggtgttttag tgtatcgtcc
    43501 gtacacggtt gaagaggaga tgcctgcctc tggtacattt ctgattgcga aaaaagcagc
    43561 aaagaaagag cttgctgtac cggaagaagc tttgacaaac cgcttcatgg cttctttatt
    43621 cagggaagta agaaaagcaa agcaaatgga gcgaggcgta aaatattttc caacagatca
    43681 attgtacaaa gaattgaaaa gacgttcaga aaatcaagat ccattttcta acgaacgata
    43741 ttatgaacgg tttttagagg aaatagctag tcaggcaatc aatgagttgc aagaagaagt
    43801 tatcgcgctt cagcatgatt atgaatattt gaggcaacaa cagcagatcc gtcggttgcc
    43861 tacagagcca ttggagtgaa aaatatgtac tatccttatt taagaggaaa acaatttgac
    43921 ctattagcat taaaagaagc actgtcgcga ggattgctct ccaataaaat ccaaccagtg
    43981 atcgaaccag tacgtgattc cgctacgctt aaaaatgtga tcgaattatt tcaaaaaaag
    44041 caccatccaa tcgctgtgat ccaaaatccc caagtaggac aattcaaatt attcgatcag
    44101 catgtgcaca gttggacagt caaagaaaat agctctgtcg tccctgcaca gatcttaacg
    44161 ccagaaaatc tcagtgaagt actggattca cctccagcgt ttcttgtttt cgatggacag
    44221 cactacccaa aagatacaga ggtgtggaaa cagttggcag gagttgattc gaaatttttg
    44281 ataccagata ctagtcgctt tcgcatctgg ctgcccgaaa acaaaattgt gatccgtgac
    44341 tcttttcaaa cgagaaagca tgttgaaagt tatgcagata aaacagatga cttttttagt
    44401 gatgactatc tttttttcca cgcagacgga tatattggat tttctgattt cacgatcgaa
    44461 ggtagccgtt atttcgataa agggttccct agccgagcgc ttgctatcca tctaacgtat
    44521 attgatgctt acggcaatat acgcgtgaaa cattttgtct ctgacagtaa cgactctgct
    44581 aaagaccaag cattgaagtt tcttgaagca ggagataaaa tgaaaaaatg gatcatgcgt
    44641 caccatcatc aactcttgat tacttcagga atgattgaat tattggctct ttaccagcaa
    44701 caaaaattcc ctggactggg agtgttgaaa aagtggtcac ttatgcatca tttggaactt
    44761 attagtcacc tgctagatca tccaaaagat tggcttaaat attattcaaa agttcaggaa
    44821 ctatatgaag tgatccaatg attagataat gtaaatgaaa aaggaataga aaagaggaaa
    44881 ctggatgtat attcggcaaa caaggaaaga agaagtagaa gaagtggtag aaatcattaa
    44941 tgccgcagcg gatttcattg cttcgcaagg ctctcctcaa tggcaaaacg ggcagaaacc
    45001 aacaaaagaa acgattttga acgatattga aagaaaagaa agctatgtat taatagtgga
    45061 agatcaaatt gctggaacag ctgcattagt ctcaagcgtg gatcccgttt acacaaaaat
    45121 agatggtagt tggaaagaat caactggtcc ttatttatcg attcatcgtg tcgctttagc
    45181 agaaagtact cgaggaaaaa aactagcaaa accgttctta gaacatttgt tgacgattgc
    45241 agccagcaaa aatatccaag atatccgtat cgatacttat ccagctaatg aaccgatgga
    45301 aaagaccatc tattctgctg gattcactta tcaagggatg attgaatttc cttttgaaca
    45361 cggcgaaaga aaagcatatc aaataatcat caattgacta taaaatcatc tgagcaaaga
    45421 taaagacatt aacactactg aaaaaaacaa tcatatgata gccaagaggt tgtaacagaa
    45481 gtggccagct tcaaaaaaca agaaagaatt tccgaaaatg cttctcaaat ttttgtggaa
    45541 ttttagcgta ttttacgaaa tagctgcttt ctgaaactcc cttcatcgag aggtcgtgac
    45601 atagcttttg tcacgacctc tcggcttatc ctacgagtat tattcgatac atttatatca
    45661 ataatccttt ttttatttta tctgcagctt cttggaacgc tccatcgttt gacacgacta
    45721 aaagtgaggg gatagctttc aaacgtttca actgtgctaa atcttctaca taaaccgcca
    45781 gtctggctga aatctgttca gatgaatctc cacgtttttt caggcgcgat tgcaatgttt
    45841 ctttagagat cgtaataaag ataggacgga ctaccgtccc gaaatactca tataaatgcc
    45901 aaaaaccatt tgctgtcaaa acggcgtaac aatttcctac tgtcagtttc tttttaattt
    45961 ctgctttact ggaaccatat ttatgttgag catattggtc ccactctgca aactcatttc
    46021 ccttgatcat ctgattgaat gtattgtcag aaacaaaata ataatcctct tgatcttttt
    46081 ccccaggtct tggtgatcga ttcgtgtaag taatgatctt ttgttccggc tgaaaaatag
    46141 cttctgcgag tgaagttttt ccagaaccag aaggaccgat aaatacatag caataattca
    46201 ttgtcatttc tcctttgatg attgaacaag tgaaaaagct ttggaaaata tttccaaagc
    46261 ttttaaaagt aactttgctt ttttgtatat tataccagca agccagtcac aatagcactt
    46321 aaaaagctga ctaaagtcgc tgttagcaaa attttcaatc cgtgttttgc gacaagattt
    46381 cctttttctt catttaatcc cttcatcgca ccagaaatga tcccgataga agagaagttg
    46441 gcaaatgaaa cgaggaagac agatataatt gctgttgtac gctcagtaaa atggaaatta
    46501 ccatttgcta attctgtcat agcaacaaat tcatttgtaa ccagtttagt cgccatgata
    46561 ctaccggcat ccactgcttc tttccatggg attccgctga tgaaggcaag aggggcaaag
    46621 atgtaaccta ggatctcttg gaaagtgatg ccgaatatcc cgtggaagat agcattgatc
    46681 atggcaatca aagcaacaaa accgataagc atagcagcaa ccgtgatcgc cacatggaaa
    46741 ccatcaagaa tgtattctcc caacatttgg aaaaatgtct gttctttgtt ttcttcaatg
    46801 atcagctcat cttctttttc ttctaataca tagggattta caattgaagc cagaatataa
    46861 ccgccaaata agttcaaaac aagggcagtg atcacatatt tagaatcgat cagtgccata
    46921 taagatccga cgatcgacat agaaactgta gacatagccg atacactcat ggtgaacaaa
    46981 cgtttctcag ataggaaggg taattccttt tttatggaaa taaaaacttc cgattgtcct
    47041 aaaatagcag aagctactcc attataagat tccaatttgc ccatcccgtt gattttactt
    47101 aatcctagac caacagcttt cataaataat ggaagaatct tgatatagcg tagaataccg
    47161 ataatagcag aaataaatac aattggcatc aatacggaaa gaaagaaagg tgcacttcct
    47221 ttatttgcta caccggcaaa aacaaagtca acaccttgcc cagcaaaagc aagaagatga
    47281 tcaaacattt ttgccaatac agaaacaacc gctgtaccaa aagttgtacg taataatacg
    47341 aaaccaagaa caagctgtaa aacgaacatc acaattagtg gtttcaattt gattgctttt
    47401 ttgttactgc tgatcaaaaa agcaagccct aatgtgacaa ataaaccaat aatacctaat
    47461 aaataactca aataatcact cctattccaa attccgtttt attttacctg ttttgcaaat
    47521 aaaatactaa tctttagtga aattttcatt acttttttag agtgaaacgc attcattttc
    47581 cattagaaaa taaagcgaac aaaataaaag gtttaaaaag tgtaacgtct tagtaaagtc
    47641 tataaaaaaa cgaaactatc gattaagcta atagtttcgt tttcaacatt tataagtaaa
    47701 ctttttctat tggtaatata gattttcgga agggtagaca ggtgcgcagg taatatcgat
    47761 tcctagtttt ttcaatgttt gttcatcatt tttattgacc atcacagtag agtgggcttg
    47821 tgctccctca agttcagcta gtttatcata agcaacttga gcgattggat tcgttactgc
    47881 actgattgat aaagcgatca agacttcatt gatgcttagt gcatccaaag aggaatgaag
    47941 tgtctttgat ttcaatcctt gtattgtttc aagaactaat ggtgacaata aaggaatgtc
    48001 atctgcgata tgggctaaat gttttactgc atttaagata actgccgctg acgcatccat
    48061 caatgaactt gtacgcccgg taatgatgac ttcatctggt aattcgattg caatcacagc
    48121 agaaggatct tttgtaggac tttgcgcttg aatcttatct gcatagtcat gggcagggac
    48181 taccacgttt cggtcttcag gacgtaaacc gacttcttcc ataatcagtt tgattcgatt
    48241 aactgcttct tcgtcgatca atcctttttt gaagtcgcat tctgtttgga aataacgacg
    48301 gatgatttct tgtttagagg cttcttggac aacggtatca tccacgatcc caaatcctac
    48361 acgattcaca cccatgtcag taggagattg ataaacagat tctttaccag taattttttc
    48421 aataatacgt ttgattacag gaaatgtctc aacatcccga ttatagttca cagctacttt
    48481 attgtaggca tcaaagtgga aggaatcgat catattgaca tcttttagat cgactgtggc
    48541 tgcttcataa gcaatgttca gcggatgttt caacggaaca ttccatactg ggaaagtttc
    48601 gaacttggag taaccagctg catgtccttt ttggctttca tgatacagtt ggttcaagga
    48661 agtagcgagc tttccacttc ctgggccagg agctgtcact acaacgattg gtttagttgt
    48721 ttcaatatac tcattttttc caaaaccatc ttctgagacg attttttcta cgttgactgg
    48781 atagtcttcg atttctgagt gtttatagac cttgatgttt cgtctttcta gtttattgat
    48841 aaagactttc gtggcaggct gtccactata gcgagtgata acgacactgt tgattaataa
    48901 gccataacca cgtaattcat cgattaaccg caagatatcc atatcataag taatcccata
    48961 atcaccacgg atcttattac gttcaatatc tccagcatag acgcaaatca gtatttcagc
    49021 ttgatctttc aatttttgca gcaatttgat tttcgcatct tcttcaaatc ctggaagtac
    49081 acgtttcgca tgcttgtcgt caactagctt cccaccaaat tctaaatata atttgtcata
    49141 gtggttcact cgttccaaaa tatacgctga ctgctcttca atatattttt ctgaatcaaa
    49201 accaattttt ttcactaggt tccctcctta agtactaaag cattttttca tttttttgag
    49261 gattcgtcaa ctggaagagc gaaattcctc aaaaaaacaa agaaaatggt ttaaaccaac
    49321 ttgtctagat agttattcat tggtatgata gtttttgata aggaaggtgc tacatgaaaa
    49381 aaagacagaa aaagaaaaac gcatataaac actatatccg ttcgattttt accggttatg
    49441 aaagaatgct tgaagatccc gaattggaac aattgacgtt tacttatcta aacgaagaaa
    49501 cgcagctaac tcgtgatgag catcagcgca ttcatttcac aacaagagat ctgcctagta
    49561 aataaaaaat aagataaagg tcatcggatt cgattctgtc ctatcagatg gaaagactag
    49621 ttgatcgaaa aaaaggctgt accaaatttt ggtgcagcct gttttatgga gcattgcccg
    49681 ctctttttta taacaatttt ttacagaaaa tggtactatt gaagtattaa taagtgaaaa
    49741 acagatgagt aagaggaggc aagtagtatg aaagagccag atacaaatgc aaattatgag
    49801 ccagacgaac tagaggagac gaatgcggat caggatacag gacaagaatc gtcttctttt
    49861 tacgatatca aagaaaaagc aagcatgaat ctttcccaat tattagaaga cttacaggct
    49921 tttgaaaaag ctgtccgcga agaagatatc cctgagatct accgtttata caatggccga
    49981 ttgaatgaag aattaaaaag aagctcaaat gaaaatcacg agatcgatca attgctgatg
    50041 cgtaagatcc atgatcgttt tttacaggaa tttcctttta tggaacaagt agaaaacatc
    50101 tcgccaacga tgagctatta caaaatcggc acttattacc atgatcggcc cacggtcggt
    50161 attgatgcaa gtctgccaga aatttttgtt ttgcctaaga tcgatgaaga gtgggagaaa
    50221 tattcccaac cggagtcaac ggactatgac aaaaaaatca atgagctaga cgcaaaggtg
    50281 atcactgctc agacagaaat tgaacgttta gatgaacaaa taaaagaaat caatcgacaa
    50341 atgactgatt tgaacgacaa taaaggattc ttgaatcgta aaaaaatcga ggaagaaatt
    50401 caagaattag agaagaagaa gcaagtacta tctaatgaaa aattaggctg gcttccttat
    50461 attgagacgc ctgaaacaat ccagcagcaa aaagaagcat tgaagcaaga agcaagagca
    50521 gaccagcttc gtgcagccat cgtagaaaaa gaacaaaggc aaatcagacg ctatttcggt
    50581 agcaaagagg gattcggtca agcaatccat gaattcttga tgaattatct tggcaatgag
    50641 aatcctaata atcaatctaa tgaaggaggt tccgagtatg aatgaacacg atgaagcaga
    50701 atggacaaaa aatgaagaac aaacagaaga tcatgaagaa acgaacactt cattggaaga
    50761 acaaacaagt aatcctctgg atgacacaga agaaatccct atgctagagg aaacaaaaat
    50821 acacgaaaaa gaaaaagtaa ctccgacgaa tacgaatact gcagaaaaca cccatgctta
    50881 cgaaataact gaaaatcccg ggtatttaga aggaaaagag caagatcatc aagatatcgt
    50941 cagtttgatt gaaacagcgg aagcagaatt agcggattta cgtatgagaa aagatttgat
    51001 cgaatcagat tttccacaat tattagaatc atatgatcgt tttatattga atgaagaacc
    51061 aatctccacg atcggaaaga caagcctgat cgaatacttc acgtatgaat tactgaaacc
    51121 gttgaatgat attggtctgg aacggtcaaa ttcagcttat gacacatgga aaacaagaca
    51181 tttttcgatc aattatacgt tgaatggaca aaacgaatta gtcttttcct ttgtattacc
    51241 gaccatcgat caacgatacc aagtggaatc gatgagtctc ctaaacgtat caccagagac
    51301 aatggaaatc aatgtccaag atgaccgggt gctttctttg atccgacact ggtcagtgga
    51361 tcgagtattc tctgcagggc agatcacgat attcaatcac aaattgaatc aattattagc
    51421 ccatgcaaga acacttggtt ttaccgttaa tcagacatta ctagacaata cgaagccact
    51481 tcgtttgaat cttcagagcg aatttgaatt gacgaatgaa gtattggatg atatttttat
    51541 cgtggcaatg aaaaatccat cctacgatat ggaaaagatc aacgaaacta cttatcaagt
    51601 acgattagat aaaggacagt ctttaacgat aacaacaaac gaaaaagatc aaacagtctt
    51661 gtcgatctca tctggagact acccacgatc tgtcattgat ttctttatca attacgaatt
    51721 cttggtccca ttaatggtga gaaagtcctg attggataag ttggattacc agatgtcatt
    51781 cagataattc tgttccaaag gacttgcggc agttatccag aataattgtc acaagtcttt
    51841 tctgtatgta ctaaatggac gtgaataact tgctgatgaa ggagggattt cattaggaat
    51901 gtccacaaat aaaatagcac agcttagctt attgtctgct gcttgtgtag caggtaggat
    51961 cgcttttcaa tttattccga atttccagcc aatgactgct atttttttat ttatagtact
    52021 ttacttaagc ttaaaagatg cgttaattgt catgagtctt tctattgcga tcagcagttt
    52081 ttattttggt gttggaccat gggtcatcgg ccaatggatc agctatactg ttgttctgag
    52141 tttgttttca atcgtctgct tgagaaaaac agtgcaaagg aatctatggt taaagggagt
    52201 ctgttttttt ctggcgggca tggtttacgg aataggtatg accgtttttg atacgctgtt
    52261 atatcgtttg cctcaacctt ggatctatta ccttcaaggg gtgtcgtttg atttgatgca
    52321 cagtataggc aatgttgtgt tctttcttgt ttttctgcca gtcgtcaaac gtttttacaa
    52381 tcattcagga ggaaaaaatg aaaaaaataa tttatagttt gcttgcaatg agtgtcagta
    52441 tactcatttt gacaagttgc agtacaacct atacacaatc ggcttccaac caaaaggagg
    52501 aagtaaaaac atcgcaaaaa gcaacaatca cgttacaaga aaatggtcaa aacttttcgg
    52561 aaaaagaagt gttcttcaaa aaaggcgatg atttactgag tattttgaaa cgaaattttg
    52621 aagtcaaaga agataacggc ttcatcactt cgcttgaagg gcactcacag gatgagaaaa
    52681 atcaactcta ttggatgttt actgtggacg ggaaaagtgc tactactggt gccaaagaga
    52741 tcaaattgaa tgatggacaa tcggtcattt tcaatttgtc taaactataa gtttcataaa
    52801 aaactgttaa agggcgaata ttgccataat tcagtgagtt cagttgatga aagaaggaaa
    52861 ataacatgga aaattttaaa aaaagcggaa tgttttccgt aattgctgct ctaggggcta
    52921 atattctagt tgctatcagc aaatttgtcg gctatgcaat cagtggcagt gccgccatgc
    52981 taaacgaaag catccacagt atcgttgatt gcagcaatca gattttgctg ttattcggtg
    53041 ataaacaagc caataaagga cagagcgagt tgcatcaatt tggtgaagga cgagcaaaat
    53101 actttttcag tacaatcgtc gcaatgatgc ttttcttcgg cggtggggca cttggggtga
    53161 tggaagcttt tgaaaagttg acgcatccat cccatgaagt gggtaatccg atcattgtta
    53221 tagcaatact gttatttggt ttggtaatcg aaggaagttc gttacgcgtg gcaatgaaag
    53281 aaatcaaaga attgaatact gaaaaacttt ccacgatgcg ctttttgcgc gaaagtcgac
    53341 acagtgaaat actgattatt tttacggaag acttgtgtgc tgtaatcggt ttggtcttgg
    53401 ctttagcagg aacaatattg acttatgcaa ccgggattgc tgcatttgat gcgatcagcg
    53461 gattgctgat cggtttcttg ctgatgggag ccgccatttt cctagcaaaa gaattttata
    53521 gtctgatcat cggtgaaagc gtgacagcaa gcgatttatc aaaaatcaag ttagcttttg
    53581 aacgtcctga gatcagtcgg ctgatcgata taaaaacagt tcatttaagt ccaacggaga
    53641 ttttagttgc agcaaaagca gatatcgttg gtaacaaaga gaatgaagct tactcggtca
    53701 tcaatgatat tgaaaaaaat atgcgtcagt ctcttcctga caagaagatg tatatataca
    53761 ttgaaacaga taaatatgac ccaaattatt ctcgtaaata aaacgtttat tcatgaattg
    53821 aagcaaaaat gagaaaaata taatcttgtt tttaaataaa acggctacaa tttagcgaat
    53881 ttatgttaca atgagtccgc tgtttatttg ttgtaattaa aggagatatt ttaatgaaca
    53941 aaaagaaaag tgcgccatgg cttcaagctt tgcatgcagt gatgccactt tgtataagct
    54001 atataccagt aggattagct tgcggagtat tgttgcaaaa agttggattt gatcctctct
    54061 tatcaggact gttatcgatt ctggtctttt ccggtggcgc gcagttttta gttgcatcta
    54121 tgcttacgac gcaagcatca tttgcaacga cattattgat ggttttcttt ttagaattac
    54181 gctatacatt attaggagca agtcttgccg gttttatgaa aaaagaaaag cggacgtttt
    54241 tggctgtctt ttctcaatca ctgaatgatg aaaactatgc ggtgaactac ttaaagtttt
    54301 caactgaccc ttcctggaat aaaagaaagg ctttatatgt caattggttc tcaatgactg
    54361 catgggccgg tagcaatatg atcggtaatt ttttcggctc ggtgattcga gtagatgctg
    54421 accttgtcca ttttgctttg acggccatgt tcattttcat gtttatcatg cagatgaaaa
    54481 gcgcactact gatctttaca ggtttattct caggcgtatt aggggtcgta ttcatggtat
    54541 tattccaaaa tactttcgga ttgattgcag caacagtcat tgcttcattt gccggattta
    54601 tgctggagaa ggcattcaaa aaagaaaaag ctaagaaact aagagaccgc ggtaaagatg
    54661 tcaatgagcc gctcttcaac ttcccggaac aggaggccaa tcaccatgac taaactatat
    54721 ttgctacttt tagttgcttg tctgttcatc gtggcatata tcccgcgctt gttcccgatg
    54781 ctttatttta ctcatcgaaa agtgccatcc tggttcagtg actggatgaa atatgtaccg
    54841 gtggcattat ttgcggcgtt agcttttaaa gatgttttca ttactcatga acatctggat
    54901 attgcttgga atatcaaaat agctgcaatg attctagtag caggcgtggc ttacaaaaca
    54961 cgttcgatgg cgttgtcagt tttgacagga cttgcgtctg tctttttgct gtctatgctt
    55021 taaactgttt tattttatta aaaacagaga ttgcgacata agttgttcaa actgatctat
    55081 ccgaactgca tttgcaacag tcaattctgg atgcaagttt attcgtaggg ataaaaaaga
    55141 ttagtgttgg cttatgatgc aagctctttt ttattttagg aattagagag ggatttgtcc
    55201 ttctatgatt ttttgctata atagggaaga tgtttatttt atgaaagaat agttgaggga
    55261 atttaaatga ataaaaaatt gatgcaagga acattttggc taacctttgc taatcttcta
    55321 tgtaaagttt taggggtagt ctatttgatt ccctggctaa gtatgatggg gaacaatcaa
    55381 gatggtatgc ttgctacgac attgtataat gttggctatc ttccttatgg attgttcctg
    55441 atgcttggta cagtcggatt tccaaatgcg attgcaaaaa aagtagctgt agccacaaaa
    55501 gaaggagata acgctgcttg tcggctgatt tttagaagta cgatcaatat catgtttgtc
    55561 atcggtatcg cctctgctgc actgatgtat ttatttgctc ctttactagc cggaatcagt
    55621 ccgattgcta acgttaataa tgggatacta gctatcagaa gtttatgccc atctttgatt
    55681 gctatcccaa ttcttagtgc aatgagagga tatttccaag gaaaaaatga tctgcggcct
    55741 tatggaactt ctttgattat cgaacaggct gtgcgagtga tcgttatctt ggctggtact
    55801 tattacttgc gcgtattgac tgacggaacc atattagaag ctgtattgat cagtacagtc
    55861 gcttctttct tcggtgggtt agctgcgatt atccatatgt atatcgtcgg acgcagaaaa
    55921 gacttcttcg aacttaaaga ttttttgatt tccagccgtt atttcgaaag agaaaaccga
    55981 tctgcctctg tctctatcat tcgggaaaca ctaccgttta tttttgtcgg ctcagtcatt
    56041 actatcgttc aaatgatcga ccaagtaacg atgaaaccac tgcttcactt tttccgtcca
    56101 gagatcgcag atcagcaact ggaattctta ttcagccgtg cttctgtcaa tccaaataaa
    56161 ttgacattga tcctgatctc catggtagga acagtagcta taagcagctt gccaatatta
    56221 agcacgatga agaaaaaaga tcggatacaa atcgaaaaaa cagtaggaga tagtttttcg
    56281 attgcgttat tgattcttct tccttcattg actggaatgt ctttattagc tggaccacta
    56341 tacacattgt tttttggcta tgatcctgaa agtgtcggat atttccaaat ggctttgcta
    56401 gcttctttgt ttttctcttt attcacgatc ctatctacga tgcttcaatc tttgaatcac
    56461 catcgttttg cgatccgatt aactgtagaa gcaattatcc tgaaagtcat cttccaagta
    56521 atcggattag gattagttgg cggatacggg atgagcttat caaatggctt agcattcggt
    56581 attgtctttg ttcgcggcta tcactttatg tgcaaagaat accgaatagc acctttagca
    56641 aagatcagca attttttctt aaaaactttc cgctccaccc tgattatgct tgcagtatgt
    56701 tttgccgttt tctttttgct gaatcagcga ttgtcaatgg aatcaaaaag ctatgcaatg
    56761 atttattgtg tggctgtagg aagtattggc ggcttagtat ttttattttc tcaattcgga
    56821 aaaaatgggt ttcgaatgtt gaaaaatgtt aaacatcata gcagaagcaa agaataggtt
    56881 aactaatcgt tttttgctgt cacttgaaaa acggcaactc gtatgattac gcttgtcgtt
    56941 tttctatttt ccaattttag tttcatatct aatcttactt atgatatagt tataaggtct
    57001 ggaaaaattc tttgaaacga ggaaattaaa cacatgaaac ttgcagtagt tacagatagt
    57061 tcggcatatc tgccggaacg tatcaagaac catcccgact tattcgttat tccaatccct
    57121 ttgattatgg atgggaaaat ttataacgaa ggaatcgata tcgaagcgga tgaatattat
    57181 ggacttttaa aaaacagtaa agattttcct actacttcac aacctgtcgt aggggaagtt
    57241 ttgggtttat atgaggaatt gaaagagaaa gggtatgaca cgattttaag tatccatctt
    57301 tcttcaggga tttctggctt tgtcaacaca ttatttgcga tgaaagatga catcagcgga
    57361 gtaacggtca ttccttatga ctctaagatc actagtatgc cgatgggaca catggtagaa
    57421 gctgccttag acttaaatga tgaaggtcag tcccttgatg aaatacttgc acatatcgat
    57481 cgaatccgag ataataccta tgcttatctg attgtagatg atttgaacaa tttagtacga
    57541 ggaggacgtt tgacaaatgg tgcagcgctg attggcagct tattaaaaat caaaccgatc
    57601 ctgacatttt ctgaagggaa aattgtttta ttcgaaaaaa tccgttcaag taaaaaagca
    57661 tttgctcgag ctgaagaaat tattggtaga agaaataacg aaatacaacc gccagtcaaa
    57721 ctttacgtga tacatgcaaa taatttagaa gtagcgattg cggagaaaga gaaattgcag
    57781 aaaaaatatc caaatgcaga aatcgaaatt ggtcatttcg gaccagtcat tggtacacat
    57841 ttaggtgaaa aagccatcgg cattgccatt tcagcgcaat aattcctttt attcaaaaaa
    57901 cataccaaaa atat
//
LOCUS       DAIGTA010000013        57846 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.013, whole genome shotgun sequence.
ACCESSION   DAIGTA010000013 DAIGTA010000000
VERSION     DAIGTA010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.013"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            330..1175
                     /locus_tag="NOB43_000795"
     CDS             330..1175
                     /locus_tag="NOB43_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0981679.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="NOB43_000796"
     CDS             1456..2676
                     /locus_tag="NOB43_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HCI0981680.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="NOB43_000797"
     CDS             2673..5393
                     /locus_tag="NOB43_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0981681.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="NOB43_000798"
     CDS             5377..6321
                     /locus_tag="NOB43_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0981682.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="NOB43_000799"
     CDS             complement(6390..7400)
                     /locus_tag="NOB43_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0981683.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="NOB43_000800"
     CDS             complement(7580..7924)
                     /locus_tag="NOB43_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI0981684.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="NOB43_000801"
     CDS             complement(7917..8351)
                     /locus_tag="NOB43_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCI0981685.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="NOB43_000802"
     CDS             8489..9226
                     /locus_tag="NOB43_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981686.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="NOB43_000803"
     CDS             9219..10430
                     /locus_tag="NOB43_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981687.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="NOB43_000804"
     CDS             10634..11416
                     /locus_tag="NOB43_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HCI0981688.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="NOB43_000805"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="NOB43_000805"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCI0981689.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="NOB43_000806"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="NOB43_000806"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HCI0981690.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="NOB43_000807"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="NOB43_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCI0981691.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="NOB43_000808"
     CDS             15018..16067
                     /locus_tag="NOB43_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HCI0981692.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="NOB43_000809"
     CDS             16064..16342
                     /locus_tag="NOB43_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCI0981693.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="NOB43_000810"
     CDS             16317..16787
                     /locus_tag="NOB43_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HCI0981694.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="NOB43_000811"
     CDS             16804..17106
                     /locus_tag="NOB43_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981695.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="NOB43_000812"
     CDS             17123..17494
                     /locus_tag="NOB43_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HCI0981696.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="NOB43_000813"
     CDS             17466..17825
                     /locus_tag="NOB43_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981697.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="NOB43_000814"
     CDS             17997..19004
                     /locus_tag="NOB43_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0981698.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="NOB43_000815"
     CDS             19029..20213
                     /locus_tag="NOB43_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCI0981699.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="NOB43_000816"
     CDS             complement(20650..22233)
                     /locus_tag="NOB43_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0981700.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="NOB43_000817"
     CDS             complement(22811..22954)
                     /locus_tag="NOB43_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HCI0981701.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="NOB43_000818"
     CDS             complement(23177..23656)
                     /locus_tag="NOB43_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0981702.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="NOB43_000819"
     CDS             complement(23729..24013)
                     /locus_tag="NOB43_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981703.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="NOB43_000820"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="NOB43_000820"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="NOB43_000821"
     CDS             complement(24357..25643)
                     /locus_tag="NOB43_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HCI0981704.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="NOB43_000822"
     CDS             25781..26452
                     /locus_tag="NOB43_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HCI0981705.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="NOB43_000823"
     CDS             26418..26906
                     /locus_tag="NOB43_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HCI0981706.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="NOB43_000824"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="NOB43_000824"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCI0981707.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="NOB43_000825"
     CDS             27867..28631
                     /locus_tag="NOB43_000825"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCI0981708.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="NOB43_000826"
     CDS             28864..31077
                     /locus_tag="NOB43_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HCI0981709.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="NOB43_000827"
     CDS             31088..31534
                     /locus_tag="NOB43_000827"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCI0981710.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="NOB43_000828"
     CDS             31705..32964
                     /locus_tag="NOB43_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HCI0981711.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="NOB43_000829"
     CDS             complement(33053..34000)
                     /locus_tag="NOB43_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0981712.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="NOB43_000830"
     CDS             34394..35686
                     /locus_tag="NOB43_000830"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCI0981713.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="NOB43_000831"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="NOB43_000831"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCI0981714.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="NOB43_000832"
     CDS             37579..38454
                     /locus_tag="NOB43_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0981715.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="NOB43_000833"
     CDS             38720..40603
                     /locus_tag="NOB43_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCI0981716.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="NOB43_000834"
     CDS             complement(40678..40962)
                     /locus_tag="NOB43_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI0981717.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="NOB43_000835"
     CDS             complement(40952..41686)
                     /locus_tag="NOB43_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HCI0981718.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="NOB43_000836"
     CDS             41815..42438
                     /locus_tag="NOB43_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCI0981719.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="NOB43_000837"
     CDS             42630..43751
                     /locus_tag="NOB43_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HCI0981720.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="NOB43_000838"
     CDS             43758..46886
                     /locus_tag="NOB43_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HCI0981721.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="NOB43_000839"
     CDS             46905..50099
                     /locus_tag="NOB43_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HCI0981722.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="NOB43_000840"
     CDS             complement(50245..50952)
                     /locus_tag="NOB43_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0981723.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="NOB43_000841"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="NOB43_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI0981724.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="NOB43_000842"
     CDS             52447..53100
                     /locus_tag="NOB43_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HCI0981725.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="NOB43_000843"
     CDS             53326..54324
                     /locus_tag="NOB43_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HCI0981726.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="NOB43_000844"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="NOB43_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCI0981727.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            56513..57808
                     /locus_tag="NOB43_000845"
     CDS             56513..57808
                     /locus_tag="NOB43_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0981728.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT        19012 a        10015 c        11959 g        16860 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat catgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttttttaa ggctctatac
    56401 tttttgatgt tggtgaactt caccaacatc ttttttgtat aaaaaaatat agaaaagaca
    56461 ccctgaaatc ctttagaatt aatttggcta ccaattcata ggaggattca agatgtctca
    56521 tactcagctt atcaaagata ccctaaatat tctagaccta aatatctatt tcgaggaaaa
    56581 ttgtttaact aaagaaaaat acaaagggca aatttgcttg atttacaaag gaactcttct
    56641 gtacaagcca gaagagtgtt cccattgtct ttgtgtcgtc ccctctagga tcattcgttg
    56701 ggggacgaca accgttcggt tgttactgaa tgatgtgtct gagtatcgca cttatctgga
    56761 gctgaagaaa caacgattta aatgtaagtc ttgccaaaga acattcgtag cggatacctc
    56821 tgttgctgaa aaacactgtt tcattagtca aaaagttcgt tggtctgtca ttgctcgctt
    56881 aaaagagaat acttccatga cggaaatcgc tcgtcagaaa aatatttcca cttcttcggt
    56941 ctatcgtgtc atgaagcgat tctaccgccc attgaatcct ttcaaacaga ctttgccaaa
    57001 ggtcttatgc tttgatgaat tcaaatcggt tcgaagtgtt gccagtgcaa tgagttttat
    57061 catgatggac ggacaaagcc atgcattatt ggatattgtc gaaaatcgac gcttgcctta
    57121 tttagaacgc tatttttctc ggttttcatt agcgactcgt gaagccgttc aattgattgt
    57181 tattgatatg tatgcgcctt atgtttcgtt ggtgaaaaag cttttcccga atgctcagtt
    57241 gatcatcgat cgtttccaca tcgtccaaca tattggcaga actttcttga atcatcgagt
    57301 gaaagaaacc acggtacgac ttaaaggaaa ttcccactct caacgagggt tagggaaaaa
    57361 attgaagcgc tattggaaac tcctacaaaa agaagaagca aagttaaact atgaaaaacg
    57421 ggtttggcgt gccagtttta aagattattt gactgaaagt gagattgccg atcgactgtt
    57481 agctgcttgt cccaacttac gccaaggcta tcagttatac caagacattc tttatgcggt
    57541 aaagaaaaga gatcagtcac tatttgagga ttgtttaact agagacatta gcggtctgcc
    57601 agaaacctat acaaccactt tacgaacgtt taaaaagttt ctgccacaga tccaaaatgc
    57661 gcttcactac agctattcaa acggaccatt ggaatgctta aacaaccaca tcaaagtatt
    57721 aaaacgcaat gcgtacggct ttcgcaactt ttacaatttc aaactacgaa ttatgattcg
    57781 tcatggcaaa acatttttaa ccaaataaac agaacagaaa gaggttttct tctttctgtt
    57841 ctgtcc
//
LOCUS       DAIGTA010000014        57505 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.014, whole genome shotgun sequence.
ACCESSION   DAIGTA010000014 DAIGTA010000000
VERSION     DAIGTA010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.014"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(61..2424)
                     /locus_tag="NOB43_000846"
     CDS             complement(61..2424)
                     /locus_tag="NOB43_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HCI0981729.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2872..3093
                     /locus_tag="NOB43_000847"
     CDS             2872..3093
                     /locus_tag="NOB43_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0981730.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="NOB43_000848"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="NOB43_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCI0981731.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="NOB43_000849"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="NOB43_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCI0981732.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="NOB43_000850"
     CDS             complement(5894..6205)
                     /locus_tag="NOB43_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HCI0981733.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="NOB43_000851"
     CDS             complement(6202..6495)
                     /locus_tag="NOB43_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HCI0981734.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="NOB43_000852"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="NOB43_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCI0981735.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="NOB43_000853"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="NOB43_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCI0981736.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="NOB43_000854"
     CDS             complement(8333..12685)
                     /locus_tag="NOB43_000854"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HCI0981737.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="NOB43_000855"
     CDS             complement(12897..14606)
                     /locus_tag="NOB43_000855"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCI0981738.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="NOB43_000856"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="NOB43_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HCI0981739.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="NOB43_000857"
     CDS             complement(16103..16903)
                     /locus_tag="NOB43_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCI0981740.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="NOB43_000858"
     CDS             complement(16900..17712)
                     /locus_tag="NOB43_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HCI0981741.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="NOB43_000859"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="NOB43_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCI0981742.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /locus_tag="NOB43_000860"
     CDS             complement(18467..19189)
                     /locus_tag="NOB43_000860"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCI0981743.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /locus_tag="NOB43_000861"
     CDS             complement(19325..20206)
                     /locus_tag="NOB43_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCI0981744.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="NOB43_000862"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="NOB43_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCI0981745.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="NOB43_000863"
     CDS             21446..21925
                     /locus_tag="NOB43_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HCI0981746.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="NOB43_000864"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="NOB43_000864"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCI0981747.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /locus_tag="NOB43_000865"
     CDS             23226..24011
                     /locus_tag="NOB43_000865"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCI0981748.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /locus_tag="NOB43_000866"
     CDS             complement(24357..26048)
                     /locus_tag="NOB43_000866"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCI0981749.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="NOB43_000867"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="NOB43_000867"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCI0981750.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="NOB43_000868"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="NOB43_000868"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCI0981751.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="NOB43_000869"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="NOB43_000869"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCI0981752.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="NOB43_000870"
     CDS             30332..31033
                     /locus_tag="NOB43_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0981753.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="NOB43_000871"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="NOB43_000871"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCI0981754.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="NOB43_000872"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="NOB43_000872"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI0981755.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="NOB43_000873"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="NOB43_000873"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI0981756.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="NOB43_000874"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="NOB43_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCI0981757.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="NOB43_000875"
     CDS             complement(34528..35508)
                     /locus_tag="NOB43_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0981758.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="NOB43_000876"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="NOB43_000876"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HCI0981759.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="NOB43_000877"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="NOB43_000877"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCI0981760.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38265..38432
                     /locus_tag="NOB43_000878"
     CDS             38265..38432
                     /locus_tag="NOB43_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HCI0981761.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38494..40305)
                     /locus_tag="NOB43_000879"
     CDS             complement(38494..40305)
                     /locus_tag="NOB43_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HCI0981762.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40302..40667)
                     /locus_tag="NOB43_000880"
     CDS             complement(40302..40667)
                     /locus_tag="NOB43_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HCI0981763.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40830..41225)
                     /locus_tag="NOB43_000881"
     CDS             complement(40830..41225)
                     /locus_tag="NOB43_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0981764.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41243..42205)
                     /locus_tag="NOB43_000882"
     CDS             complement(41243..42205)
                     /locus_tag="NOB43_000882"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HCI0981765.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42205..42417)
                     /locus_tag="NOB43_000883"
     CDS             complement(42205..42417)
                     /locus_tag="NOB43_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HCI0981766.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42438..43136)
                     /locus_tag="NOB43_000884"
     CDS             complement(42438..43136)
                     /locus_tag="NOB43_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCI0981767.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43156..43698)
                     /locus_tag="NOB43_000885"
     CDS             complement(43156..43698)
                     /locus_tag="NOB43_000885"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCI0981768.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43830..44834)
                     /locus_tag="NOB43_000886"
     CDS             complement(43830..44834)
                     /locus_tag="NOB43_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI0981769.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44831..45820)
                     /locus_tag="NOB43_000887"
     CDS             complement(44831..45820)
                     /locus_tag="NOB43_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI0981770.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45817..46623)
                     /locus_tag="NOB43_000888"
     CDS             complement(45817..46623)
                     /locus_tag="NOB43_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981771.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46789..47745
                     /locus_tag="NOB43_000889"
     CDS             46789..47745
                     /locus_tag="NOB43_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0981772.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47822..48340)
                     /locus_tag="NOB43_000890"
     CDS             complement(47822..48340)
                     /locus_tag="NOB43_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0981773.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48428..48577)
                     /gene="rpmG"
                     /locus_tag="NOB43_000891"
     CDS             complement(48428..48577)
                     /gene="rpmG"
                     /locus_tag="NOB43_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0981774.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48805..49251
                     /locus_tag="NOB43_000892"
     CDS             48805..49251
                     /locus_tag="NOB43_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCI0981775.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49446..51341)
                     /gene="asnB"
                     /locus_tag="NOB43_000893"
     CDS             complement(49446..51341)
                     /gene="asnB"
                     /locus_tag="NOB43_000893"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCI0981776.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51666..52640)
                     /gene="bsh"
                     /locus_tag="NOB43_000894"
     CDS             complement(51666..52640)
                     /gene="bsh"
                     /locus_tag="NOB43_000894"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCI0981777.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(52974..53061)
                     /locus_tag="NOB43_000895"
     tRNA            complement(52974..53061)
                     /locus_tag="NOB43_000895"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53027..53029),aa:Ser,seq:cga)
     gene            complement(53206..53772)
                     /locus_tag="NOB43_000896"
     CDS             complement(53206..53772)
                     /locus_tag="NOB43_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0981778.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54028..55359
                     /locus_tag="NOB43_000897"
     CDS             54028..55359
                     /locus_tag="NOB43_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HCI0981779.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55325..55675
                     /locus_tag="NOB43_000898"
     CDS             55325..55675
                     /locus_tag="NOB43_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981780.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55767..56186)
                     /locus_tag="NOB43_000899"
                     /pseudo
     CDS             complement(55767..56186)
                     /locus_tag="NOB43_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(56187..56531)
                     /locus_tag="NOB43_000900"
     CDS             complement(56187..56531)
                     /locus_tag="NOB43_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCI0981781.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            56797..>57505
                     /locus_tag="NOB43_000901"
     CDS             56797..>57505
                     /locus_tag="NOB43_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0981782.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT        16221 a        12140 c        10050 g        19094 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 tccattttcc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagcg agggcgttac
    34681 atatttcgct acactgacat cattgaagcc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aagtgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgccggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct aggcgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat cgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccatttt tccaatactg agttagctgc ttcaataagc
    36061 aagtttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatcttc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaattggt
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg ggaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taatcgcttt gatatctgtg tattcaggtt tccagcccag aatctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaaggctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tctttcggct ctccataagt tgctgcagta gaagagaata
    37681 cgattttatt cacgttgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattct atataattta aaaaacgaag tttactttta tggtgaaaac
    38101 aaacaaagta aaatttcgta aattcatatg gtaaatttat aataaaacat ttagtaaaca
    38161 ttttcaagga ttttttgcaa aggtttacaa acaaacgtaa aactagcctt tttttctctt
    38221 ttgttccata atagatataa caaataataa atgaggtgga ttcaatgaaa aaatttgtat
    38281 ctggaatatt agtaggaagt ctggcaacag ccgctgccgt tgctggtttg gttgcttctg
    38341 tgaaaaaaac agtgatcgat ccaattgacg aaaaagaagc aatgatcgaa gaaaaccgta
    38401 aaaaagcaat gcgtaaacgc gtttctcgtt aataattatt taaaaatacg catgaagact
    38461 ttctaaaaaa cagataagtc atcatgcgta tttttatttg tcagtcaata taagttgtgc
    38521 tattttatct gcctgtctca gattccatgg atctgtataa ggtctagcta ctgctgcagt
    38581 tagccaatcc acaccttcaa caggtattcc atagcaataa aagtcagact ggatttcccc
    38641 tgaagcatca atcacgcgat tcgtacctcg ctcaacatct atagcttctg aatgataact
    38701 tcctgtatta tctgaaaatg aaaaagggcg aacaagtttg ttttccttca aattttttat
    38761 gacaggatta cttgaacgag aaaagcttgt ttgtggcaat cgagcttcaa tcaaatagcg
    38821 actgctgatt tctttatctt gtagagaaat aacatagcgg ttgtgctttt gctgaatatc
    38881 aaatggcggt tcgatcaaat gaaaaatacc cgcatctatc agtgctgcta attctttcgt
    38941 ccgaatgatt ggcggaccga tcgttaaaaa gctatttaga tgagtaaacc atccccatag
    39001 tatttctttg tattccttag cagaaaaaac gtgccattca atagcctgcc ggattggatc
    39061 acgccagtct tttaatgcat caaatgttga agcaaatgct cctgtgcaat tgcctttttc
    39121 cgcttctttt atctgccctt caataaatat tcggctagct tctgaaaagg gctcattctg
    39181 ataggcaaga ggagtttcta aatacgacca atcccatcta taagggatta gtgctggatg
    39241 ctttccgaga cactcctctg aagagaggga gagaaaatca tgctcaaaat ttttctttgg
    39301 aatcggcaag tgatattctt cgatgatttt cttgtaataa aacaactcaa cgtctttttt
    39361 cagatagtca aaaaatgttt cgccagtcaa aaatcccgac tgatgccatt gctccaggtt
    39421 ttcttttgtt agtaaccgtg gccatgccat tgctccgcct tgcttttgat ttcttcctcg
    39481 agggtaataa gggagccccc ttcttgatcc actgtataca atcggttcct tgcctgatgg
    39541 atgatagacc agttttccct tttcgttctc gaagcgccct cctcttgata ctgtaaacaa
    39601 tccgacataa tcaaaaaaac ttaagcctag acctcttaaa aagacatttt ctttaggcgg
    39661 tatcttcgaa agatctacat ctgcaggatt agaaggaagc tgatacagta aaacattttt
    39721 ctttgcgtag tctacccaca ctctttcttc ttctgtctca tcattttccc agtgaccgct
    39781 tgctaaaaca agctgatcga tagaatagct ttgctgatct gtctgtaaaa gataaccatc
    39841 ttttcttttg cttacttttt ttactaaaga ataaacaaac tgaatagaag ctggaaattc
    39901 ttcttgcaac tttgagaaaa accagcgttg atagagtccg tataaacatc gagtagattg
    39961 ctgatctttt tccagacgat tgatttcttc tataattagt tgcttatttt tggttaccgt
    40021 ctgttcgata taatctgtag caggtccttt actccattga aacaagttgg gtccctgtgt
    40081 taccaatcct ccactggaca atgtttcatc tgtaaaaagc gtcacttgtt gagaaacaga
    40141 attcattaat aactccggtg gctgattcaa ccgccaaact cgacctccag gaccattggg
    40201 atcgaaaaga aaaagttcaa gagaatgtct gtcctgatta ttatggagaa tcctttctgc
    40261 tacacttaat cctctaggtc cggcaccaat gatccctatt ttcatttgca tgcctccatt
    40321 tcgataaatt ttttcaataa aacagcatgg ttctgatgtt cattttttgc accataaaca
    40381 aaagtaatga ctggatgttc tttcataagt tgactgagtt taaaaatagc ttgcttcttt
    40441 tcttcttcga aaatcaattc ttgctggtat ttctttgcaa atgaagcaaa tcgttctggt
    40501 acatggtcaa aagttttgcg tgcttcatta ctaggtgcaa tttctttcaa ccacagatct
    40561 aactgcgctt tttcttttga aattcctcgt ggccagaatc tatccacgag tattctatag
    40621 ccatcctctt tttcagcatc aaggtaaaca cgttttaatt tgatcatagt tgtttccttc
    40681 tttctacctt ttcgcttagc ttatatatgt agataatagc acaaaataaa aaaaatgaac
    40741 ggcacaacta tccattgcgc cgttcatgtg atcttggtca aaatctaatg attgattcgg
    40801 tttttaaagc tgtcatacaa tcatctgttt tatacttttt tacttttgat ttttccagac
    40861 catccgtcat atccaccctt aagtaaataa atctcttgat aacctgcttt acgtaattta
    40921 tttgctgtac ggatgctcaa acttttcttt tgatcgtaaa tatagacagg ctggtctttt
    40981 cgaatagatc ctaatgaatc tttcaaaaca gtgtaaggga tgtttcttgc acctaaaata
    41041 tgcccagcat caaacacatc tttttcgcga acatcgatta cttgtgcttt tctcattcct
    41101 tctcgaaatt cttcttctgt caaagtcgtt gctgaacgtt tggccattac tcgtagatag
    41161 acttcccaaa ggatgattgc aagcacaatc aatagcaaaa tgatattaat tacccataaa
    41221 accatgtaat gcctccgttt ttttaagcaa atttcaaggc taatgaggca gcaccaatga
    41281 caccagcttc attaccaagc tctgctaatt tgatttttgt tgattctctt acttgcggga
    41341 aagtaaattc tttaaaatat ttctctacac ggctacgtaa aaattctcct gctgccgata
    41401 ctcctccacc taacacgata cttgacggat ttaatgtatt ccccaagttt ccgcaagcta
    41461 aacctaagta gaagcatacg cgatcaacaa ccatcaatgc aaacggatcg tcttcttgag
    41521 ccatttcaaa gatatcttta cttgttactt cttctccgtt gtctagcatt gctttcagtt
    41581 ttgaatcccc tgcgtattct tctgccaaga aacgacctag gcgtaccaca cctgtagcgc
    41641 tagatacagt ttctaaacat ccgcgtttac cgcaagtaca ttcgaaccct tcaggatcca
    41701 cagtgatatg tccgatttct cctccagctc cgctcacgcc gtgaatcaaa tttccgccag
    41761 caacgatacc tccgccaaca cctgttccta gagtaacgaa tacaacgtct ggatcgtttt
    41821 ctccagcacc tttccatcgt tcacctaaag cagcaacatt cgcgtcatta tcgatagcga
    41881 atttgattcc tgttcctgcc tcgatcagtt ttttcacaaa ttgaacttct gtccagttta
    41941 agttatacgc accaataacc gttccagctt cgctgtccac gcttcctggg gtacccatgc
    42001 cgattccgat aaagtcttcg gctttcatat tatataaatt caaacgatga ttgattgatt
    42061 caatgatttc aggaacgata tgcttaccat catccaaaat attggtatcg atgctccatt
    42121 tttgctgaat ctctccttct ggtgttaaaa ttgcaaattt tgctgttgtt ccacctaaat
    42181 caatcccaat aatcttcttg tccattacaa atttcctttc tttcggcttt cttcaattcg
    42241 gtgctctctt tttaatatgc gccacgctgt catgtatgta tcatgatcaa tcaaacggct
    42301 atcatacaga ttacgcaatt cgatagtcat taattcaatg tcatagatgc gtgcacccac
    42361 atagataaag atgccaaatt ttttgaacag ctgctgtaca tcatataagc tctccatctt
    42421 taagcacttc cttcatatta tacaagtaaa ccatattttt ttaaacccag taaaatacat
    42481 attacaaaaa gaaatacaaa aactagtgta gaaagaatcc tttggtgtat cgaatagctt
    42541 gtctgttgtt tcggtagacc caaaacattc cctaacacta atccgccaat tagcccaccg
    42601 acatgtcccc aaacatctac agaggtatcc agaagaccaa aaacaaatgt caacacaata
    42661 aataaaagaa aatgtctgac tagctgctgg atcgctgggt tatgtttaaa atgaaaccct
    42721 aagataaaca acgcaccgaa caaaccgaat atcgaagtac ttgcaccacc agacagaaca
    42781 ttcgcttcgt taaaagcaaa gcttgctgta tttcccatta tcccgctgaa catataaatc
    42841 aagaaaaaac gccaatggcc atagattgcc tcgatttgct gccccataaa atacagtatc
    42901 agtgagttca ttacgaaatg catcagtcca aaatggatga agattggtgt cactaaacgc
    42961 caccattcat tgaagtgaac aagataagga ccatacattc cggcataata agggatctca
    43021 agtcgcggaa ataattccat catgaggaag accgctgtct gtatccctaa aaaagcatag
    43081 gtccataacg gtcgtcttaa ccatgcacgc aattttattt gctgttgata attcatgaaa
    43141 acctcccatt tcattttagt caataaacaa ttgttggatc ttctgatcaa agctctccgg
    43201 ttgccattgt tcattcaatt gttcacgaaa aacaaggcta catgtttttt tatgaaaatt
    43261 atttaaatac cggtcgtaat aaccaccgcc aaaaccgatt cgataaccgg ctctattgta
    43321 gataatacct ggtacaatga ggagatcgat catctccggc aaatagagct tctctgattg
    43381 tggctcaaga acaccaaaac tcgaacgtac aagaacggac tgttcatcca tttcataaaa
    43441 cgccatctga cgtttcggca aagttttagg tacaactatt ttcttttgtt ctttttctgc
    43501 tcgttggata accggctgtg tatccagttc aaattcattc gataaagtcg tccctatcac
    43561 ttttgctgac ttccagtact cgctggcgaa tagctgttta tagattcgct gttctttttc
    43621 ctttttcttg ccacttttgg ccagattttt cagcttttcg attcctttcc ggcgtaatct
    43681 tactttcaat tggtccaaaa actcaccctt ccttctctca taaaatggta taggaaaaaa
    43741 agaaaaatag caatcgaact ttcaaataaa tgcataaata gaataaaaag aagacctaga
    43801 aatgattggc cttccttttt taatgaattt caactgttca gcgcgtgttt ttgtctgata
    43861 aaaagtgcat acagaaaata tggcgcacca aaaagggcaa tcaaaattcc tgtaggtact
    43921 tccccactta gtagaatcac tctagcaacc atatctgcac taagcagaaa aatggaaccg
    43981 aacaaaccgc tcagaacaaa ggtccagtta ttttctttac gtacgactag cttcgcagca
    44041 tgaggagcta gtagtcctac aaaagataaa ctacctgtca ccgctacact accgcttgcc
    44101 aaagcaacag ctaacaacaa aaggattttt tgacttttag ccacgttaag gcctaatcct
    44161 tgcgcgcgtt cttgaccaaa tgatagcaat acaatcctct gtgcataaag tcctcctagc
    44221 ggaattaaga taaccgccca tggaagcaat gcccaaacat aaggccagct cgcaccccag
    44281 attgatcccg ctaaccatgc attcacaaat ccataatttt ccttagataa ttggatcgtg
    44341 catagcaatg ttaatgcaga aaggccggca ttaacggcaa taccggacaa taagattcga
    44401 ttcataccca aaaagccatt tcgatcatag gccgcaagat agacacagca agcagctaaa
    44461 acaccaccta gaaaggctac aactagcaat agaaacggca gcgaatagtg cgaaaagaaa
    44521 cctaaataaa gcatcactaa aaatcctgct ccggcattaa tgcccaatat actagaatct
    44581 gccaattcat ttcttgttac tccttgcaag atataaccag aaacgccaag acaagctcca
    44641 gctaataaac tgatcagtaa tcgaggaact cgaaattctc taacaatcag cgccaaagaa
    44701 gatgattctt tccctatgaa cgtggcaaaa agctgatcca ggtaaataaa aggcgtacca
    44761 atcattaaac tacctataga caggatgaca agtacaaaaa gcaagaaata gaacgtccaa
    44821 tatatttttt tcaccgttgt tccctcctta cttgtatcag taaaaacgga acgccaatca
    44881 atgcaatgac taatccaaaa ggtgtttcaa aagggggatt gatcatcctc gctgtaaaat
    44941 ccgccaacat aaccaatcca ccgccaacta aaaaagagac aggtagaaca taacgatagt
    45001 ccgttccaac cattccgcga acaactggcg gaaccaacag cccaataaat gaaacaggtc
    45061 cgactaacga aacggcaatg gctgctaaca ctgcaactag acagaaaaca atcaaccgcg
    45121 ttcgtttagg atgacttcca agagctaatg catgtgtttc actcaaatga atcaaagata
    45181 ttgcttttcc taatgaaaaa gaaaccaaaa cagcaagtat atataaagga aacaatactg
    45241 ctaattgttt ccatgtgata ttggcagctc cgcctacaaa ccaaaaagca agatcctgct
    45301 gcagattaaa gaattgggta agtgcttggc tgatagcagt aaaaaaagaa ctaatagcta
    45361 cgccagctaa aatcagctgt aaaggattca tgcccatttt cgaaaactgc aaaaaaccaa
    45421 atacgagcaa agttacagca aaagaacctg ccaatgacat tagaaacaca gaaaaatcag
    45481 aagctttagg ccaaaaagca aaactaaggg ccattgccaa cgaagcaccc gcgttgattc
    45541 ctagtaagcc tgaatctgct aaaggatttc ttgtcactcc ttgcatcaat gcaccgctca
    45601 atgcaaaaca actccctaca agaaatgctc ccgccacacg aggcaaacga atatttcgta
    45661 tgatttggtg actttgtttt gatctatcaa aatcaaacaa cgcctgccaa aaatctgctt
    45721 ttcccacagt cgctgcgcca tttgaaagag caacaaaaaa aataatcaaa agaacaaaac
    45781 agaccaaaag caggagtcta tttttcttca tagtcctcat aattgatcct cctgctcttt
    45841 tggcaacaaa tcataggtta gaaaaactgg tttatttgtt cttggaagcg tgacaatcgt
    45901 tgcatcaatc tcaaatattt ttttcataca ctcttttgtg atcacttctt caggtgtacc
    45961 ttctgtgatc aacttaccgt ttttcattgc taataaataa tctgaaaaac gtgaagcatg
    46021 attaatgtca tgaatcgaca tcaagatcgt tgtttgtttc atttgattga tttcagtcaa
    46081 taactgtagg atctctaatt ggtgtgccgg atctaaaaat gttgtcggtt catccaagat
    46141 caagatatct gtttcctgag caagcgccat agcgatccag acacgctggg tttgtccacc
    46201 agacagcgtt gcgatatccc gcatacgaaa tccagctaga cctgtagcat ccaacgccca
    46261 ctcaattgct tcatgatctt gcgtgtccat gccactgaac agtttttgat aagggtatcg
    46321 tccgtaagat actacttctt ctactgtcat acctgtaggg tgttcactag tttgtgctaa
    46381 taatgcaatt ttttttgcaa gttcttttga actgtatgta gagatatcag agttattgac
    46441 aatgatcttt cctgatttca caggtagtat acgggtaaaa cttttcaata aagtagattt
    46501 tccacttcca tttggcccaa tcaaactagt gattttccct tcaggaatcg taacagacat
    46561 gttttcaatg atttttttgt tttcgtagcc ggctgcaatg tcagctgctc ttaatctcgt
    46621 catttcaccc atcctttcgc tgaaaatcat tctcaattat gacgctgttt caacatttcg
    46681 tcaagcgcta ctttcatatc tatagccaaa tgaagcggtt gacagcgttc gaaatatcag
    46741 gaataataac caatgagaaa gattctcaat tatgttagga ggaaagaaat gaaattaaaa
    46801 acaaaagtat tcacattatc tagcatattg ctgctggctg gagtactgag cgcttgctcc
    46861 ccctcttcag ataaagaaac agctacaact gccaattcga cgacttcatc caatagtact
    46921 catacagtca cagatacact tggacataaa gtagagattc caaacgcgcc caaacggatc
    46981 atcggcagtt acttagaaga ctatctgatt gcactagggg aaaaacctat cgcccagtgg
    47041 actgttggca gtggttccat tcaagattat ctgcaagatg atttaaagga tgtcccaacg
    47101 atttcttatg accttcctta tgagaaagtg ttaagctttg agcctgattt gctgttgatt
    47161 tcttcttccg ctactgtcga aggcgggaaa tacgaacaat atagcaaaat cgcgccaact
    47221 tatgttgtaa aaaacggaac agatgtcaca tgggaagaac aactaaaaga tgtcggcaaa
    47281 gctttggcaa aagaaaaaga ggcagaaaaa atcatttccg attatcaaaa atccatcaag
    47341 aaaactcgag aagaactagc agataaaatc gagaacaaga cagctgcagt gttgtgggtg
    47401 accaacaact cagcctttat ggtcagcaaa aatcggtcaa gtggaagaat cgtatacgac
    47461 gatctggaat ttggtgttcc tgatctagtg gaagaggtct ccaaaaaagc cacttctgac
    47521 tggtctgctg tttcctctga aaagctagct gaattagatg ctgactacat catccttgtg
    47581 aacagtgaca aagatgctgc catgttcaat gaaccaagct ggaagaatct aaaagcagtg
    47641 acagacaatc atgtactgca attcggacct gaatctagtt ggctatataa cggacctatt
    47701 gccagtcagg aaatggtcaa tgatatcaaa gaaaaactaa attgatttta actaaaaaaa
    47761 gcatcttcac gattagtcgt gagatgcttt ttttcttatt aacaaactag acgcatagat
    47821 tttattcttc ttttgaagca accctatttt ttactctttc ccatttttga aaacgatggg
    47881 catatagatt ttcttgatcc gttatcccct catactcctc tataagggcg aagtctgaaa
    47941 aatcaatatt cccaatatac gtatcgcctt caaacgtgct atcgatcaat gttcgccaga
    48001 tccgaccagt gtaaggaaga agttcttgaa aaatccgact accacccgaa acatagatat
    48061 cttctgagat cgtttgacta tacgacaaaa gttcatcgat cgaatgcatt acttccgcat
    48121 tttctttcgt gcgaaaattt ggttgcgttg tcaacacgat gatatggcga taaggaagtg
    48181 aaagatcccc cattccttca taggtctttc ttcccatcac taaaattcga tccattgtgt
    48241 gttcgcgaaa gaaacgcata tcatttggca atcgccatgg taacaaacca tttttgccga
    48301 tcagaccatt tttatcttgt gcccacatgg aaataaacat attatccgct ccttatgatt
    48361 ttagatgttt tgagataaaa aaagtctcaa ttctttgacc agcaaggaat tgagaacttt
    48421 aaaaacatta ttttgtttca cggtgcaaag taactttgcg ttcgcgtggg caatattttt
    48481 gtttttccaa acgatcagga ttgttacgtt tgtttttgct tgttagatag ttacgttctt
    48541 tacaagaagt acactctaaa gtgatgttta cgcgcatgtt tttccctccc atttttacaa
    48601 gaatcctcta agatgactct cagacttgat tatcttacca tgattttttc tagattgcta
    48661 gtgtttttca cgattttgtt aagtaaaact acttgacgat aaatacaacg gttttacttc
    48721 tcaaacaaaa tctttttctt tttgtataaa tacccttaca cttgtttata tagattatgt
    48781 tttttaataa agggggatac taatatgcca tggaacatga aggactttcc tgcatcaatg
    48841 aaaaacttag ataaattgac aagaaaaaaa gcaatcgaca tcgcaaatgc attattagat
    48901 gaagggtacc ctgataaccg tgcgatccca attgccattg atcaagcaaa aaaatggtat
    48961 gaagatgcta gtgaatcaga aaaacgaact ttcgaaaaag aaaaaaatcc aagcaagacg
    49021 gatgaacacg atacgaatcc tcgtgctgga aaactgcttg attcagatgt gatcgtagaa
    49081 tatgaggaag aacaatggat cgtgaaatct aaaggggcaa aaaaggcaag caaccatttt
    49141 gatacaaaaa aagaagcaat cgaaaaagga aagcaagtag cacaaaacaa agaatcaact
    49201 ttgttcattt ataaaaaaga tgggacaaaa gaaaaagaaa tcgattattg aacatatgta
    49261 aaggggttgt gacgaaaatc gtgtcacaac ccccttatgt tcgaaacaat ggtgttcctc
    49321 tgccaactcc gaaccataag tcataatatc tataaaacgg gaagagctgt tttttgaaat
    49381 tgtttcttat cactcagtgt taaacggtag gagaaaacct cttttttatt gatatttgat
    49441 tttcatcaaa cagtcacata gtcgattgct tctgcttgcg gaatcgtttc atctacaaag
    49501 tagactttat accatgtcaa gaaactgaag attgtccaga tttttctttg ctcttcttta
    49561 cgtccttcgt gatggtcatc tagcaacttc atgatttttt cttgatcaaa aaattctttt
    49621 gcaaaatctg cttcgaataa tgctttgact tgttcgtagc cgtgttcttc tttcaaccaa
    49681 gctttgattg gcacagggaa tcctaatttc acacgattcg accattcttc cggaagatgt
    49741 ttgttcgcag cttgtctgaa aatatctttt gtgttgtttt gattcaataa aaacttactt
    49801 ggtatttgtt gagccaattt catgacttcg atatccaata aaggtactcg gacttccaaa
    49861 gaacttgcca tagaaagttt atctgccttt aacaagatat cttttggcat ccattgatga
    49921 agatcgacat attgcatctt attgacttca tctttgattc cttctgtttt ctcgtaatga
    49981 acagtcatga tttcatccac agatggtgct gtttgatatt ttggtgttaa cacttctgat
    50041 gcttctgatt cttcgaacac tcgagcatga ccgataaaat attcttttgc aggagcaagt
    50101 gattcatata aatggatccg tccatggaaa tttttcattt ttccgatttt acgtcctaaa
    50161 ttatagcgtg ttccttttgg taattttttc aatccttgag caatcacacg gatgaatttt
    50221 gaattcgtat ggaatccata cgtttggtat cccgcaaaca gttcatccgc cccttctcca
    50281 gattggacta cccgcacact ttgtgaagca agatttgcta aaaagtacaa aggtacgcaa
    50341 gaaggatttg aatcaggttc atctaagtga tactggatca aagggaatgc tttgaacgac
    50401 atgtctccgt cgatcactgc tgctgtatta tctaagtcca atagttcggt tagttttctg
    50461 gcttcaatcg cttcattata ggttttatca tcaaacccga ttgagaaaga atgatctggt
    50521 ttcaatacag aggttacata actggaatca accccgctgg ataagaaaga accaacttct
    50581 acatcactga ccgtatgtgc ttcaatagaa gcttgaacgg tttcgtcgat tttttcgatc
    50641 cattcttgtc gggaatgcgt ttcttttgtt tcaaaatctg catcccaata ttgctgaatg
    50701 tctatttttc catctttata cgtataataa tggccttcag gcaaacgata gacatctttg
    50761 aagaatgttt cgccgtttaa tggagaatat tggaaagtca tataaggttt caacgcttct
    50821 ttgttcaatt ctttgttaaa atcaggatga ggcagaaaac ttttgatttc tgaaccaaac
    50881 ataaatgttc cgttcatttc tgcataataa tatggtttga tcccaaagtg gtctcttgca
    50941 ccgaataact cattcttttc attatcccaa atagcaaaag caaacattcc gcggatcttt
    51001 tgcaataatt ctgttcccca ttcttcgtaa ccatgcaaaa ggacttctgt atctgcatgt
    51061 gtttgaaaaa cgtggccagc tgcaatcaat tcttctctca aaggctggta attatagatt
    51121 tcgccattaa aaataatgat ctttgtccga tcttcattgt aaataggctg agtaccgccc
    51181 tctaagtcaa taatacttaa tcttctgaat cctaaagcaa catgtttatc gatatattct
    51241 cctgaactat taggtccacg gtgaacgatt cgatccatca ttgtattaat aattgttttt
    51301 ttgttgtcct tgtcgttaac aaaacctaca ataccgcaca tttaactttc acatcctaat
    51361 ataaaattac tgtttatttc attcatatgc atcttatcat agaataaata gcggacgaat
    51421 attttctctc ttacaatttc gtcacgtgaa aacaaaagat gaaagtttct gtttttacag
    51481 aaaataaagt cccaatatct aatttaccat gttttctttt ttgaggctac cttattctct
    51541 tcgtgttaaa aaaatattag tggatgctat ttccaaaaaa accagcaaaa aaagacacga
    51601 cctaaagatc gtgtctaatt atgactgtat cagaaaatat gataccaaac ggatctattc
    51661 attaattaat tgacatagtt tatctgttgc tcttttatga ctggataact gaccaattca
    51721 tgacgatcca agtcttcttt attcatattt acagcagtaa tttgactgtc ttcatacgta
    51781 cgataataat aaatcccttt atcaacgtta cagcaagaag aataaatcgt atattcgtat
    51841 tttctttctc cagtatcgca tactcctttt tgttgctcga ctgagcctag tatatgaaaa
    51901 aattgactga tactttcaga ttctgaatca cctgatgcag cattcatttt agtaaatgtg
    51961 gcttttacaa atcgagaaac agaagagaga tctccaggta agcccaatcc tcccatccca
    52021 cgactataaa cattcaagct gatctggttt gaaaaatgat tttctggtgt tccatttgat
    52081 agcgagcgat aattgttcag attaaataat tgataatcaa atggcggatt atttgtcaac
    52141 acaccgacag gattatcata taaatgaagt ccatctttca tactttcaat tactatcgat
    52201 ttttctttat cagctaataa ccagtgtaaa ggtgacaagg gtagtttttc actaaaatcg
    52261 atattgacta gattgatagt agccaataat tctttagctt cgtctatggt tgagcattgc
    52321 cctagtatcc atggaataaa ctcaaatggt gcaacgttat cttttccttc ttgtaattct
    52381 ttataatcag cattgccagg aaaattcagt cctgccatac tcaacccttt ttcatttgta
    52441 gcctcataat agagtggata gttggatacc ccagctgcta ttcctatcat tgcataatgt
    52501 ttatctaaat tttttacctt tctaaaatcg aaacgataat ttcttggagt aatagtgacc
    52561 acttcattat aagacatctc ataatcaaaa ttccttccaa aataatggtc tttcgttgca
    52621 taagtgattg cggtacacat cgtttcccgt cctaaaacaa atcgttttta cacttttatc
    52681 ttacatctag tatttttttt atcaaaaaaa ggccaaagaa gattgattta ctagcattta
    52741 taaaaaatag tactcagggg gaatcaaaaa atattgtagg ttaaaagtac aacaataagg
    52801 ggctgtgaca aaagtcttgt cacagcccct tattccgaac aaacggtgtt caaaagcttg
    52861 catctgcggt aataagccca atcaaacgaa aaaataggaa aagctatttt tgtttggccg
    52921 ttcttattac ttgatgcagg acagcttctt cacaacctct aatcgttgat ataaggaagg
    52981 tacaggattt gaacctgcgc gccggtatta gccggttcgc cggatttcga gtccggtgca
    53041 ttaccactct gccaaccttc cgtaagtact atttttaaac ttttttcacg aaatgtcaag
    53101 cctatttcta atagataaat aacagaaatc gcttttttta gcaaaaaagt ccattgacag
    53161 tttgcagcca acggacttac cgatcaaatt catactgata gaacactatc tgattatttc
    53221 aggattatct aatgctaaaa tcgagtcaat tgtccgtttg atcagtgcaa tgatttgttc
    53281 ttctgttgga tgcatgatgt ttgatgacat caatgacgct aagccagtca ctgctaccca
    53341 tgtaccagta tgcagagcat cgacatattc atccgataat tgattgtatc tttcatcttc
    53401 tttaactatt tcacggaaat aattgtatga aaaatcatgc attttctttc cgtccccatg
    53461 ttcatcaatg tacaatgcca tgtaaagact atgatgcttt tttgcaaagt agatatagtt
    53521 caaaccgaga tcaatgattt tatcaccagt acgttcaata gggaaaacat cttcttttag
    53581 ttgttcaaag atagaatcca gcaacgtatt ttttaaatct tccatgtttt tgaattccag
    53641 ataaatcggc tgtgtcgaaa tccccatctt tttagcaata tttctcgcag taaatccttt
    53701 aaacccttcc tttgcaacaa catcataagc agcttttaga atttgatcct tggtatagac
    53761 ttttcttctc attaaaactc ccccacttct ttactgcagt atatgttgtt ttattgtacc
    53821 ctatttttag cattttttgc aaacatttta ctcaaaacgt tatattttaa attttttttc
    53881 agtcttcttt aacttttttt tgcaaaatta aaaaaatttg gttaaattca atgggttccc
    53941 ttacattttt agttttgacc taaataatag ttgtccaaat ctttcatttc aagttatagt
    54001 taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa ctgacgttat ttatattcat
    54061 cctcaaaaac gaatcgtttc acagaaaaga aagtattttt atcttggttt tacaggtgtt
    54121 ttttttcttt ttattggctt gctttctaat actcctactg ataattggag tggattgcta
    54181 actattctta cctcgccaag caatcttttg acagattatt ttgctttagg cggtttcgga
    54241 agcgcattca taaatgtagg gattttgacc ttactttctg tgcttttagc ttatcggcac
    54301 aaggtgattt taaacggtcc cttatttgct tcgattctaa cagttaccgg tttctctttt
    54361 tttggcaaaa acctttataa ttctatctca atcattttag gtgtgtatct atacgctgta
    54421 tttgtcaata aacctttttc tcagtacatc atgatcggac tgtttggtag cgcattatca
    54481 ccggtcgtta gttatatcac ttttggtatg cgttttcctt tactgatagg tattttattg
    54541 gggaatttag ctggcatagc aattggtcta cttcttccgc ccttagctgc tcaaacttta
    54601 gttttccatc gtggattcac actttataat attggattca cctctgggtt gattgcgatg
    54661 acttttactg ctgttttgag gttattcagc tattcaatcg tcgaaaatac attggttttc
    54721 aatgaatatc actttcctct catttggatt atttttggct ttttttcgct gacagtcgga
    54781 attggtttct attataattc ctttcggctt ttggggattc gagaaatttt cgattcatct
    54841 ggaaaattga caactgattt cattgctaat tctggtattg gtgctacttt gatcaacata
    54901 ggcttagttg gtctgatgct gtcttcttat gttttgctgg ttggcggtca gttaaatgga
    54961 cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg cttttggttg tcatttaaaa
    55021 aacagttttc cgatactagt cggaatattt attgcttctt tgtttggaac ttttcatgag
    55081 atcaccagta ctggcatgct tgttgcagct gtgtttggga caggtctcgc gcccataagc
    55141 ggtttttacg gcagttttta cggtgtaata gctggtgtac tacatattgc tcttgtccat
    55201 aacgtcagca ctttgcacgg aggactaaat ctatataaca gtggtttttc aactggtttc
    55261 gttgcaggta tccttgtacc gatactagat aactttaccg ctgtcagaaa ggaaaaaaag
    55321 acacttggaa aaagaattat caaaaagaat catcgatgag cttcttactt atttatattc
    55381 ccatgaaata actgaaatac gtattggagt agaatttgct gaggaagggc ttttcataga
    55441 gatacagggt acggcagaaa ctcagccaga agatttagat gtacttgctg atttgctgaa
    55501 caatcctcgg gaccctagta tggaaatcta ttatcaagaa ctattaggta atccccgaca
    55561 tgatcgggaa gattatcatc tgttaggtag tttgattgat gacgtggaaa tcatgtatgc
    55621 ccagccgatt atcaatatta agatctttcg acgtgcttct cattcctatt attaacccta
    55681 ttttctattt ataaaagact gaatcaaaaa agcagctcct gaaagttcga ttaaaatcta
    55741 ctttcaggag ctgttcaagc ttgacattat tgattttcca atccttcata cacttcatct
    55801 gttacaggtt ctaaaaactc tgaattacca gcagtgatcg ccaaatgttc aaaccaactg
    55861 tcttttgtcg caccatgcca atgtttaatc cctttgtgcg ttacgacgac atctccagcc
    55921 attaatcgtc ttgctggctt tccttcttcc tgataccagc cttctcctcc ggtcacaagt
    55981 aagatttgat agccgtcttt atggacatgc cagtgattgc gacaacctgg ttcaaaagtt
    56041 acattaccta caccaacaga aacttcggga tcattcacta acatattcag atagctttac
    56101 ccggtaaata cttgagcgta agcttcgttt ttttcacctg ctggaaaaat cacgccattg
    56161 tgtatttctt cgtgttttgt cgtcatttac gcctctttct tatcttcgct attttcttct
    56221 aaatagattt cttttgctaa actaaaagct gaccaagctt ttggccatcc tacataaaaa
    56281 gctaaatggg taatgatttc tgctatttct tcactagtaa tgccattttg cttgccaatc
    56341 ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa ttaatgcaga tatggtgatg
    56401 atactacgct gatgagcaga taattcttct ctggaccata cttgtccaaa taaaacatca
    56461 tcattcaatt ctgcaaattt tggtgcaaaa tctcctaatt gatctcgtcc tgcggtttgt
    56521 ttttctgcca tttctcttat tctcccttca cgactgttag gtgattcaac tatggttcta
    56581 aggcaacttt attttctatt gtttcttcgc atttcatttt aaatgtagtc tttcagcctg
    56641 tccaatgctt agtttattca gtcgatatgc tttttaagca tagttgctaa cgcttttttt
    56701 attcgccgat tgtaaaatta agctagacaa ctaaaaaagt catttgtgct acactcaaaa
    56761 tagttccgtc caaagaatta taaggagtga gtacaaatga cctataccca tcttacaacg
    56821 gatgaacttg taatgataga gtcttatttc aaaataaatc aatctgttgc gaaaactgcg
    56881 catttcttga atcgttcaag acaaacgatc cataaagtat acctgttctt caagcaagga
    56941 aaatcagcct tagagtacta tcaacagtat aagaaaaaca aatcaaactg tggtagacgc
    57001 ccgcttgttt tacctgagga acaatcagaa tatattcaaa gaaaggttgt tcaaggatgg
    57061 acacccgatg tgattgttgg tcgtgcagcg tttcctattc gttgttctgc tcgtaccatt
    57121 tatcgtatgt tcaaaaaggg gctatttaat ccttctgact taccgatgaa aggcaagcgt
    57181 aaaccaaatg gacatcaaga aagacgtgga aaacaagctt tccgtcgctc tattcatgaa
    57241 cgtgaaaaag attatagcca attctcaaat gagtttggtc accttgaagg tgacactatc
    57301 gtaggtttga aacataaaag tgctgtaatt accttagttg agcgattatc aaaagttatc
    57361 atcacattga aaccgtgtgg tagacaagcg attgatattg aaaacaaatt aaatcattgg
    57421 tttgaatctg taccgaaaaa tctattcaaa tccatcactt ttgattgtgg aaaggaattt
    57481 tcaaattgga aacagatcag taatg
//
LOCUS       DAIGTA010000015        54513 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.015, whole genome shotgun sequence.
ACCESSION   DAIGTA010000015 DAIGTA010000000
VERSION     DAIGTA010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.015"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            262..570
                     /gene="rpsJ"
                     /locus_tag="NOB43_000902"
     CDS             262..570
                     /gene="rpsJ"
                     /locus_tag="NOB43_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCI0981783.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            601..1230
                     /gene="rplC"
                     /locus_tag="NOB43_000903"
     CDS             601..1230
                     /gene="rplC"
                     /locus_tag="NOB43_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCI0981784.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            1258..1881
                     /gene="rplD"
                     /locus_tag="NOB43_000904"
     CDS             1258..1881
                     /gene="rplD"
                     /locus_tag="NOB43_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCI0981785.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            1881..2171
                     /gene="rplW"
                     /locus_tag="NOB43_000905"
     CDS             1881..2171
                     /gene="rplW"
                     /locus_tag="NOB43_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCI0981786.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            2210..3043
                     /gene="rplB"
                     /locus_tag="NOB43_000906"
     CDS             2210..3043
                     /gene="rplB"
                     /locus_tag="NOB43_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCI0981787.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            3086..3364
                     /gene="rpsS"
                     /locus_tag="NOB43_000907"
     CDS             3086..3364
                     /gene="rpsS"
                     /locus_tag="NOB43_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCI0981788.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            3387..3734
                     /gene="rplV"
                     /locus_tag="NOB43_000908"
     CDS             3387..3734
                     /gene="rplV"
                     /locus_tag="NOB43_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCI0981789.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            3748..4404
                     /gene="rpsC"
                     /locus_tag="NOB43_000909"
     CDS             3748..4404
                     /gene="rpsC"
                     /locus_tag="NOB43_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCI0981790.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            4407..4841
                     /gene="rplP"
                     /locus_tag="NOB43_000910"
     CDS             4407..4841
                     /gene="rplP"
                     /locus_tag="NOB43_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCI0981791.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            4831..5019
                     /gene="rpmC"
                     /locus_tag="NOB43_000911"
     CDS             4831..5019
                     /gene="rpmC"
                     /locus_tag="NOB43_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCI0981792.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            5044..5310
                     /gene="rpsQ"
                     /locus_tag="NOB43_000912"
     CDS             5044..5310
                     /gene="rpsQ"
                     /locus_tag="NOB43_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCI0981793.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            5368..5736
                     /gene="rplN"
                     /locus_tag="NOB43_000913"
     CDS             5368..5736
                     /gene="rplN"
                     /locus_tag="NOB43_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCI0981794.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            5773..6081
                     /gene="rplX"
                     /locus_tag="NOB43_000914"
     CDS             5773..6081
                     /gene="rplX"
                     /locus_tag="NOB43_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCI0981795.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            6109..6648
                     /gene="rplE"
                     /locus_tag="NOB43_000915"
     CDS             6109..6648
                     /gene="rplE"
                     /locus_tag="NOB43_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCI0981796.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            6667..6852
                     /locus_tag="NOB43_000916"
     CDS             6667..6852
                     /locus_tag="NOB43_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HCI0981797.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            6888..7286
                     /gene="rpsH"
                     /locus_tag="NOB43_000917"
     CDS             6888..7286
                     /gene="rpsH"
                     /locus_tag="NOB43_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCI0981798.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            7318..7854
                     /gene="rplF"
                     /locus_tag="NOB43_000918"
     CDS             7318..7854
                     /gene="rplF"
                     /locus_tag="NOB43_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCI0981799.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            8015..8371
                     /gene="rplR"
                     /locus_tag="NOB43_000919"
     CDS             8015..8371
                     /gene="rplR"
                     /locus_tag="NOB43_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCI0981800.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            8392..8892
                     /gene="rpsE"
                     /locus_tag="NOB43_000920"
     CDS             8392..8892
                     /gene="rpsE"
                     /locus_tag="NOB43_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCI0981801.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            8907..9086
                     /gene="rpmD"
                     /locus_tag="NOB43_000921"
     CDS             8907..9086
                     /gene="rpmD"
                     /locus_tag="NOB43_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCI0981802.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            9130..9570
                     /gene="rplO"
                     /locus_tag="NOB43_000922"
     CDS             9130..9570
                     /gene="rplO"
                     /locus_tag="NOB43_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCI0981803.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            9570..10865
                     /gene="secY"
                     /locus_tag="NOB43_000923"
     CDS             9570..10865
                     /gene="secY"
                     /locus_tag="NOB43_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCI0981804.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            10927..11574
                     /locus_tag="NOB43_000924"
     CDS             10927..11574
                     /locus_tag="NOB43_000924"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCI0981805.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            11765..11983
                     /gene="infA"
                     /locus_tag="NOB43_000925"
     CDS             11765..11983
                     /gene="infA"
                     /locus_tag="NOB43_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCI0981806.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            12016..12132
                     /gene="rpmJ"
                     /locus_tag="NOB43_000926"
     CDS             12016..12132
                     /gene="rpmJ"
                     /locus_tag="NOB43_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCI0981807.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            12150..12515
                     /gene="rpsM"
                     /locus_tag="NOB43_000927"
     CDS             12150..12515
                     /gene="rpsM"
                     /locus_tag="NOB43_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCI0981808.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            12543..12932
                     /gene="rpsK"
                     /locus_tag="NOB43_000928"
     CDS             12543..12932
                     /gene="rpsK"
                     /locus_tag="NOB43_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCI0981809.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            13012..13950
                     /locus_tag="NOB43_000929"
     CDS             13012..13950
                     /locus_tag="NOB43_000929"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCI0981810.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            13978..14358
                     /gene="rplQ"
                     /locus_tag="NOB43_000930"
     CDS             13978..14358
                     /gene="rplQ"
                     /locus_tag="NOB43_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCI0981811.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            14630..15469
                     /locus_tag="NOB43_000931"
     CDS             14630..15469
                     /locus_tag="NOB43_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0981812.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            15445..16314
                     /locus_tag="NOB43_000932"
     CDS             15445..16314
                     /locus_tag="NOB43_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0981813.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            16304..17101
                     /locus_tag="NOB43_000933"
     CDS             16304..17101
                     /locus_tag="NOB43_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCI0981814.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            17304..18050
                     /gene="truA"
                     /locus_tag="NOB43_000934"
     CDS             17304..18050
                     /gene="truA"
                     /locus_tag="NOB43_000934"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI0981815.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(18383..21052)
                     /locus_tag="NOB43_000935"
     CDS             complement(18383..21052)
                     /locus_tag="NOB43_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HCI0981816.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(21290..21478)
                     /locus_tag="NOB43_000936"
     CDS             complement(21290..21478)
                     /locus_tag="NOB43_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCI0981817.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            21748..22110
                     /locus_tag="NOB43_000937"
     CDS             21748..22110
                     /locus_tag="NOB43_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0981818.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            22162..23844
                     /locus_tag="NOB43_000938"
     CDS             22162..23844
                     /locus_tag="NOB43_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HCI0981819.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            23961..25997
                     /gene="recG"
                     /locus_tag="NOB43_000939"
     CDS             23961..25997
                     /gene="recG"
                     /locus_tag="NOB43_000939"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCI0981820.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            26046..27047
                     /gene="plsX"
                     /locus_tag="NOB43_000940"
     CDS             26046..27047
                     /gene="plsX"
                     /locus_tag="NOB43_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCI0981821.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            27169..27411
                     /gene="acpP"
                     /locus_tag="NOB43_000941"
     CDS             27169..27411
                     /gene="acpP"
                     /locus_tag="NOB43_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI0981822.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            27679..28683
                     /locus_tag="NOB43_000942"
     CDS             27679..28683
                     /locus_tag="NOB43_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981823.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            28684..29628
                     /locus_tag="NOB43_000943"
     CDS             28684..29628
                     /locus_tag="NOB43_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0981824.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            29628..30590
                     /locus_tag="NOB43_000944"
     CDS             29628..30590
                     /locus_tag="NOB43_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981825.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            30617..31531
                     /locus_tag="NOB43_000945"
     CDS             30617..31531
                     /locus_tag="NOB43_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981826.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            31557..33338
                     /locus_tag="NOB43_000946"
     CDS             31557..33338
                     /locus_tag="NOB43_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0981827.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            33686..34372
                     /locus_tag="NOB43_000947"
     CDS             33686..34372
                     /locus_tag="NOB43_000947"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCI0981828.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            34392..37973
                     /gene="smc"
                     /locus_tag="NOB43_000948"
     CDS             34392..37973
                     /gene="smc"
                     /locus_tag="NOB43_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HCI0981829.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            37982..38791
                     /locus_tag="NOB43_000949"
     CDS             37982..38791
                     /locus_tag="NOB43_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0981830.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            38802..39800
                     /gene="ftsY"
                     /locus_tag="NOB43_000950"
     CDS             38802..39800
                     /gene="ftsY"
                     /locus_tag="NOB43_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCI0981831.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            39987..42254
                     /gene="gshAB"
                     /locus_tag="NOB43_000951"
     CDS             39987..42254
                     /gene="gshAB"
                     /locus_tag="NOB43_000951"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HCI0981832.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(42343..42795)
                     /locus_tag="NOB43_000952"
     CDS             complement(42343..42795)
                     /locus_tag="NOB43_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HCI0981833.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            42945..43895
                     /locus_tag="NOB43_000953"
     CDS             42945..43895
                     /locus_tag="NOB43_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI0981834.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            43888..44847
                     /locus_tag="NOB43_000954"
     CDS             43888..44847
                     /locus_tag="NOB43_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI0981835.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            44844..45599
                     /locus_tag="NOB43_000955"
     CDS             44844..45599
                     /locus_tag="NOB43_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0981836.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            45622..46575
                     /locus_tag="NOB43_000956"
     CDS             45622..46575
                     /locus_tag="NOB43_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0981837.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(47219..47515)
                     /locus_tag="NOB43_000957"
     CDS             complement(47219..47515)
                     /locus_tag="NOB43_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HCI0981838.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            47870..48226
                     /locus_tag="NOB43_000958"
     CDS             47870..48226
                     /locus_tag="NOB43_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0981839.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            48236..49135
                     /locus_tag="NOB43_000959"
     CDS             48236..49135
                     /locus_tag="NOB43_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCI0981840.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            49652..50383
                     /locus_tag="NOB43_000960"
     CDS             49652..50383
                     /locus_tag="NOB43_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0981841.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            50528..52555
                     /locus_tag="NOB43_000961"
     CDS             50528..52555
                     /locus_tag="NOB43_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCI0981842.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            52663..53760
                     /locus_tag="NOB43_000962"
     CDS             52663..53760
                     /locus_tag="NOB43_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI0981843.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            54067..>54513
                     /locus_tag="NOB43_000963"
     CDS             54067..>54513
                     /locus_tag="NOB43_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0981844.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        18213 a         9637 c        11691 g        14972 t
ORIGIN      
        1 aaaagagtca gtattttcta aatgaaactt tatgaaaaca aaatgttttt tacaagaaaa
       61 agccttgctt tgtgagttta tatatattat aatgacaaag gtgcgtttac tttagtgaat
      121 tgcacagacg taatcagaat gatttcgtcg gctaagaaac gagaggttgc gacacgcccg
      181 gacgctttgc cacgaacgag cgtgacggaa attttcgtgg agctatgtct acttttcaaa
      241 ataggcgaag gagggaacaa gatggcaaaa caaaaaattc gtatccgttt aaaagcgtat
      301 gaacaccgta ttttagatca atcagcggat aaaatcgtgg aaactgcaaa aagaactgga
      361 gctagcgtgt ctggtccaat tccattacca actgaacgca gtctttacac aatcatccgt
      421 gcgactcata aatacaaaga ttcacgcgaa caattcgaaa tgcgtacaca caaacgtctt
      481 atcgacattg tgaacccaac accaaaaact gttgatgctt tgatgaagct agacttacca
      541 tctggtgtaa acatcgaaat caaattataa aactaaaaca aaaataatgg aggtgtactc
      601 atgaccaaag gaatcttagg gaaaaaagtg ggaatgacac aaatcttcac tgaatctggt
      661 gaattaattc cagtaactgt tgtagaagct actccaaacg tagtactaca agtgaaaaca
      721 atggaaacgg atggctacga agctattcaa gttggttacc aagatatgcg tgaagtttta
      781 tcaaacaaac ctgcgaaagg tcatgttgca aaagcaaaca cggctcctaa gcgcttcatt
      841 cgtgaattca aaaatgttga gctaggagaa tatgaagtag gaaaagaaat tacagtagat
      901 gttttccaag caggagacat tattgatgta acaggtacta cgaaaggtaa aggattccaa
      961 ggggttatca aacgccacgg acaaagccgc ggaccaatgg ctcacggttc tcgttaccat
     1021 cgtcgtcctg ggtcaatggg tccagttgca cctaaccgtg tatttaaaaa caaacgtctt
     1081 gctggccgta tgggtggcaa ccgcgtaact atccaaaact tggaagttgt acgtgtcgat
     1141 gcagaaagaa atgttatctt gatcaaaggt aatgttcctg gagctaaaaa atctttaatt
     1201 actatcaaat cagctgtgaa agctaaataa ttgtaggaag aaaggaggaa ctaaggaatg
     1261 ccgaatgtag cattattcaa acaagatgga agccaaaacg gtgaaatcac acttaacgaa
     1321 gaaatcttcg gaattgaacc taatgaaagt gttgtttacg atgcaatcgt aatgcaacgt
     1381 gcgtcattaa gacaaggaac acacgcggtt aaaaaccgta gcgctgttcg cggcggcgga
     1441 cgtaaaccat ggcgtcaaaa aggaacaggt cgtgcacgtc aaggatctat ccgctcacca
     1501 caatggcgtg gaggtggcgt agtctttgga ccaacaccac gttcttacag ctacaaactt
     1561 cctaaaaaag ttcgtcgttt agcaatgaaa tctgtattgt cagaaaaagt tgctgaaaac
     1621 aacttggtag caatcgaagg cttgaacttc gacgcaccaa aaacaaaaga attcaaacaa
     1681 gttcttgcta acttatctat cgactctaaa gtattggttg ttctagaaaa aggtaacgac
     1741 tttgctgctt tatcagcacg taacttacca aacgtttctg tagtaacttc tgataatgtg
     1801 agtgtgctag acgttgtatc aaatacaaaa gtgttagcaa cacaaactgc tcttactcaa
     1861 attgaggagg tgcttgcata atgaacttac tagacgtaat caaacgccca gtgatcactg
     1921 aaaaatcaat gcttgccatg gatgacaaga aatacacttt tgaagtggac actcgcgcaa
     1981 acaaaacttt agtaaaacaa gcggtagaag ctgcttttga cgttaaagtc aaaaacgtga
     2041 acatcgtgaa cgtacgtgcg aaattcaaac gtatgggcaa atatgcagga tatacaaaaa
     2101 aacgtcgcaa agcgatcgtt acattgactg aagattcaaa agaaatccaa ttattcgaag
     2161 ctgctgaata agcactaata gataactcat taaattagga gggaaaaacg tggcgattaa
     2221 aaagtacaaa cctacctcaa atggtcgtcg taacatgaca ggttctgatt ttgctgaaat
     2281 cacaacatca acacctgaaa aatcattgtt acaaccattg aaaaaccatg ctggacgtaa
     2341 caacaacggc cgcatcactg tacgtcatca aggtggcgga cacaaacgcc aatatcgcgt
     2401 gatcgacttc aaacgtaaca aagataacgt tgttgcaact gttcaaacga tcgaatatga
     2461 tccaaaccgt tcagctaaca tcgcgttagt acactatgaa gatggagtga aagcttacat
     2521 cttagcacct aaaggactag aagtgggtat gaaacttgtt tcaggtccag aagcagatat
     2581 caaagtcgga aatgctcttc cattagaaaa cattccagtt ggtactgtta tccacaacat
     2641 tgaaatgaaa cctggtaaag gtggacaatt gatccgttct gctggtacaa gtgctcaagt
     2701 acttggtaaa gaaggcaaat acgtattgat ccgcttgaac tctggtgaag ttcgtatgat
     2761 cttagctgca tgccgtgcta caatcggttc tgtaggtaac gaacaacacg aattaatcaa
     2821 catcggtaaa gctggacgct ctcgttggat gcgtaaacgc ccaactgtac gtggtagcgt
     2881 aatgaaccct aatgatcacc cacacggtgg tggtgaaggt aaagctccta tcggacgtaa
     2941 agcaccagtt tctccttggg gtcaaccagc tcttggttac aaaactcgta acaaaaaagc
     3001 taaatcagac aaacttattg ttcgtcgtcg caaaaataaa taattacttt gaccatgtgt
     3061 cgcacatttt gagaggaggt tcaccatggg tcgtagttta aagaaaggac cttttgtcga
     3121 tgagcattta atgaaaaaag ttgaagctca agcaggggtt gaaaagaaaa aagttatcaa
     3181 aacttggtca cgccgttcaa cagttttccc aagttttgtt ggatatacca tcgcagttta
     3241 tgatggacgt aaacatgtac cagtttacat ccaagaagac atggtaggac acaaattagg
     3301 tgaatttgca cctacaagaa cttatcgtgg acatgctgct gacgataaga aaacgaaacg
     3361 ctaatttgag gggaggataa atccaaatgg cagaacaaat cacatcagct aaagcaactg
     3421 caaaaacagt tcgcacttca cctcgaaaag cccgtttagt aattgacctt atcagaggta
     3481 aaagtgtcgc agatgcaatt tcaatcttga aattcacacc aaacaaatct gctggaatca
     3541 ttgaaaaagt attgatgtca gcagttgcga atgcagaaaa taactttgac ttagatgttg
     3601 aaaacttggt agtaagcgaa gcttttgtta acgaaggacc tacaatgaaa cgtttccgtc
     3661 ctcgtgcaaa aggatcagct tctccaatca acaaacgtac aagtcatatc acggtagtcg
     3721 tatcagaaaa ataaggaggg ataatcagtg ggtcaaaaag tacatccaat tggaatgcgt
     3781 gtaggcatca tccgcgactg ggatgctaaa tggtatgctg aaaaagagta tgctgagttc
     3841 ttacacgaag atttaagaat ccgtaaattt atttcaacta aacttgctga tgctgctgta
     3901 tcaacagttg aaatcgaacg cgcaacaggt cgcgtaaaca tttcaattca cacagctaaa
     3961 ccaggtatgg ttattggtaa aggcggttct gaagtcgaaa gcctaagaaa agaattaaac
     4021 aaattaactg gtaaaagaat ccatatcaat atcgtggaaa tcaaaaaacc agatctagat
     4081 gcaaaattag taggtgaagg aatcgcacgt caattagaaa accgtgttgc tttccgtcgc
     4141 gctcaaaaac aagccatcca acgctcaatg cgtgctggcg ctcaagggat caaaactcaa
     4201 gtatctggtc gtctaaacgg agcagatatc gctcgttcag aaggatactc agaaggaact
     4261 gttcctcttc atactttacg tgcggacatt gattacgcat gggaagaagc agatacaaca
     4321 tacggaaaac taggagttaa agtgtggatc tatcgtggag aaattcttcc aactaaaaaa
     4381 aacactgaga aaggagggaa ataatcatgt tagtacctaa acgtgtaaaa caccgtcgtg
     4441 aattccgcgg aaaaatgcgc ggggaagcta aaggcggaaa agaagtagca ttcggtgaat
     4501 acggtttgca agctgttgat tcacattgga tcacaaaccg ccaaatcgaa gctgctcgta
     4561 tcgcaatgac tcgttacatg aaacgtggtg ggaaagtatg gattaaaatt ttccctcaca
     4621 aatcttatac tgccaaagca attggggtac gtatgggttc tggtaaaggg gcacctgaag
     4681 gatgggttgc accagtaaaa cgtggtaaaa tcatgtttga aatcgcaggc gttcctgaag
     4741 aagtagctcg tgaagcgtta cgtctagctt ctcacaaatt accaatgaaa actaagatcg
     4801 taaaacgtga ggaaatgggt ggtgaatcga atgaaggtta aagaaatcag agaattaacc
     4861 actgccgaaa tgcttgatca agaaaaacaa ttaaaagaag aattgtttaa tcttagattc
     4921 caattagcaa caggtcaatt agaaaacact gcacgtatta aagaagtacg taaatcgatt
     4981 gcacgcatca aaactgtgtt gcgtgaacaa gctaagtaat tatggaagga ggccattaag
     5041 cgtatgactg aaggaagaaa tcaacgcaaa gtttatcaag gtcgcgtggt ttcagacaaa
     5101 atggataaaa caattaccgt tgctgtcgaa acaaagaaaa accaccctat ctatggcaaa
     5161 cgcatgaact attctaagaa atacaaagtg catgatgaaa acaacacagc aaaagttggc
     5221 gacatcgtga gaattatgga aactcgtcca ttatcagcta caaaacgttt ccgtttgttg
     5281 gaagtagtcg aagaagcagt tattatctaa taacacgaga ttttcctata tagattgaat
     5341 gcaaaatctg aaaggaggat acacaacgtg atccaagcag aaagtcgttt aaaagtcgct
     5401 gataactcag gcgcacgtga aattttgacg atcaaagtcc ttggtggatc tggtcgtaaa
     5461 actgctaaca tcggtgatgt gatcgttgct acggttaaac aagcaacgcc aggtggggtt
     5521 gtcaaaaaag gtgacgtcgt taaagccgtt atcgttcgaa caaaatcagg agctcgtcgt
     5581 acagacggtt catatattaa atttgatgaa aatgctgcag tgattattcg tgatgataaa
     5641 agccctcgtg gaacacgtat ctttgggcca gttgcacgtg aactacgtga aaacaacttc
     5701 atgaagatcg tttcactagc accagaagtt ttataatctt gagacactta tcaaaggagg
     5761 tgcgaaacag ttatgtttgt taaaaaaggc gataaagtta aagttatcac tggaaaagac
     5821 aaaaacaaag aaggcgttgt actagcagcg ttcccgaaaa aagataaagt tattgtcgaa
     5881 ggtgtaaatg tcgttaaaaa acaccaaaaa ccttctcaag ctgctcctca aggtggaatt
     5941 gttgagatgg aagcgccaat tcatgtttct aacgtgatgg tggttgactc tactggtgta
     6001 gctggccgag ttggctacaa agaagtagac ggcaaaaaag tccgtgtttc taaaaaaacc
     6061 ggtgaagttt tagataaata aaagtttaag gaaggagggt cttactgaat gaaccgccta
     6121 aaagaaaaat atcttaaaga agtaactcca tcattgatgg aaaaatttaa ctatagctct
     6181 gttatgcaaa cacctaaagt tgaaaaaatc gtcatcaaca tgggtgttgg tgatgcggta
     6241 tcaaacgcta aaaacttaga taaagcagtt gaagaattaa ctttgatcac tggtcaaaaa
     6301 ccaatgatta caaaagctaa aaaatcaatc gctggattcc gtttacgtga aggaatgcca
     6361 attggtgcaa aagttacatt gcgcggagaa agaatgtacg aattcttaga caaattggtt
     6421 tctgtttcac taccacgtgt acgtgacttc catggtgtaa gtaaaaaagc ctttgacggt
     6481 cgtggaaact atactttagg tattaaagaa caattgatct tcccagaagt agattatgat
     6541 ttagtagata aagtacgtgg tatggacatc gttattgtaa caacagcaaa ctctgatgaa
     6601 gaatctcgtg agttgttgac acaattaggc atgccattcc aaaaataatt aaaggaggcg
     6661 aactacgtgg ctaaaaaatc aatgattgct aaaaacaaac gtcctgcaaa attttcaaca
     6721 caagcttata ctcgttgcga acgttgcgga cgtccacatt cagtttatcg taagttccat
     6781 ctttgccgta tttgcttccg cgaacttgcc tataaaggtc aaattcccgg cgtgaagaaa
     6841 gctagctggt aaaaagtaaa ttcgcataag aaggaggtaa aagatcaatg gtcatgacag
     6901 atccaattgc agattttcta actcgtatcc gtaacgcaaa catggttaaa catgagtctt
     6961 tagaagtacc tgcatcaaaa attaaacgtg acatcgctga aatcttgaaa cgtgaaggtt
     7021 tcgttcgtga tgttgaatac atcgaagatg acaaacaagg cgtgatccgt gttttcctaa
     7081 aatttggtaa aaacggcgaa cgtgttatca caaacttaaa acgtatctct aaaccaggtt
     7141 tgcgtgctta tgtcaaagct gacgaagtac caaaagtatt gaacggttta ggtatcgcaa
     7201 tcatttcgac ttctgaaggt gttgtcactg ataaagaagc tcgtgaaaaa aatatcggcg
     7261 gcgaagttat cgcttacgta tggtaatcaa gtagaatcta caaggaggtg tctttaagtg
     7321 agccgtatcg gaaataaagt cgttgttatc cctgaaggag taacagttac tcaagacgga
     7381 aacaacgtta cagttaaagg accaaaaggt gaattgactc gtactttttc agcagatatc
     7441 aaaatgaata tcgaaggaaa cgaagtaact ttcactcgtc caaacgacag taaagaaatg
     7501 aaaacaattc atggaacaac tcgtgcgaac ttcaacaaca tggttgtagg tgtcagcgaa
     7561 ggtttccaaa aagcgttaga actaatcggg gttgggtacc gtgcacaatt acaaggatca
     7621 aaacttgtat tgaacgttgg ttactcacat ccagtagaaa tcacaccacc agctggagta
     7681 actgttgaag taccagctaa cacacaagta attgttaaag gtgcgaacaa agaagaagtt
     7741 ggcgaattag ctgcaaacat tcgtggaact cgtcctccag aaccttataa aggtaaaggt
     7801 attcgttatg ttggcgaata tgtacgccgt aaagaaggta aaactggtaa ataatcgttt
     7861 agaaaaattg catagaagcc agcagcagga aaaaggcatt tggctgaagt ttaccttcaa
     7921 aaaaatacat ttttacttgt gccgcagctt ctatttttcg aaacgtattt actgcttgaa
     7981 atagtagtac aataaaaata aagaggtgac aattgtgatt acaaaaccag ataagaacaa
     8041 aacacgtcaa aagagacatc gtcgtgtacg taacaatatc tctggtactg ctgagcgccc
     8101 acgcttgaac gtttttcgtt ctaacaaaaa catctacgct caaattattg atgacgtagc
     8161 gggtgtaacg ctagcaagtg cctctacctt ggataaagaa atttcaggtg gaacaaaaac
     8221 agaagcagca caagctgtcg gtaaactagt tgctgaacgt gcagctgaaa aaggcattaa
     8281 agtagtagtc tttgaccgtg gtggatacct ttaccatggc cgtgtgcaag ctttagctga
     8341 agctgctcgc gaaaatggac tagaatttta gaagaaggag gaataccatt catggtttat
     8401 atcgatccaa aacatttgga attagaagac cgcgttgttg caattaaccg tgtaacaaaa
     8461 gttgttaaag gtggacgtcg tctacgtttt gctgctttag ttgttgtcgg tgacaaaaac
     8521 ggacacgtag ggtttggtac aggtaaagct caagaagttc ctgaagcaat ccgtaaagca
     8581 attgaagatg cgaagaaaaa cttagttgaa gtacctatgg ttggttcaac aatcccacac
     8641 gaagtaatcg gtgcttttag tggtggtaga atcctaatga aacctgctgt agaaggttct
     8701 ggggttgctg ctggtggacc agttcgtgcc gtattagaat tagctggggt agcagatatc
     8761 acttctaaat ctttaggctc aaatacacca atcaacgttg ttcgcgcaac agttgaaggt
     8821 ttgaaacaat tgaaacgtgc agaagaagtt gcagaacttc gcggcaaatc agttgaagaa
     8881 ttaatcggat aaggaggaca acaataatgg ctgaattaaa agttacttta aaacgcagta
     8941 ttatcggacg tcctcaaaac caacgcgata cagttaaagc gttaggtctt acaaagatta
     9001 acagttcagt ggttaagcct tctaatgaag caattaaagg catgatcaat actgtttctc
     9061 acctagtgga cgttgaagaa atttaattta gaaaaatcat aactagaaca ttaaggaggt
     9121 gccaaaccta tgaaacttca tgaattaaaa cctgctgaag gttcacgcca agtacgtaac
     9181 cgtgttggtc gtggtacttc atctggtaac ggaaaaactg ccggacgcgg acaaaaagga
     9241 caaaaagctc gttcaggcgg cggtgtgcgt ttaggatttg aagggggaca aacaccattg
     9301 ttccgtcgtt taccaaaacg aggattcaca aacgtgaacc gtaaagacta tgcagtcatt
     9361 aatcttgatg tattgaaccg ctttgaagac ggagctgaag taactcctgt tgctttagtt
     9421 gaagctggaa tcgtgaaaaa cgaaaaagct ggaatcaaag tattagctaa tggggaacta
     9481 aacaagaaat taactgtgaa agcagcaaaa ttctctaaag cagctcaaga agcaattgaa
     9541 gcggctggtg gatcaatcga ggtgatctaa tgtttagact attaaaagat gcttttaaag
     9601 taaaagacat tagatcgaaa atcctattta ctgtatttgt gttgtttgta tttcgcctag
     9661 gtgcacatat tactgtacca ggcgtaaatg ctgcttcatt gcaaaacctt tcttctttgc
     9721 catttttcaa catgttgaac ttggtaagtg gtagtgcgat gcaaaacttt tccattttct
     9781 caatgggggt ttcaccatac attactgctt ctatcgtcat tcagcttctt caaatggaca
     9841 tcgtgcctcg atttgttgaa tggtcgaaac aaggggaagt tggtcgtaaa aaactgaatc
     9901 aagcgactcg atatctgaca ttagtattgg catttatcca atctgtcggt atcactgctg
     9961 gattcaatca atacgctcaa ttaggtttcg tgaataatcc taacgtagca acttacgtaa
    10021 cgatcggttt gattctaaca gccggtacga tgtttgttac ttggctagga gaacagatca
    10081 cagaaaaagg tatcggaaat ggcgtatcaa tgatcatttt tgcaggtatc atttctagat
    10141 tgcctgaaag tatcagagaa atttatgaag attactttat aaatattgat ccttcagaca
    10201 tatggaaatc tgctattttt gtggccattt tactagtagc ggtcttgttg atcgtgacat
    10261 tcgtaacatt tttccaacaa gctgaacgca agatcccgat ccaatatacg aaacgcgtag
    10321 ctggcgcgcc tacaagcagc tatctgccgt tgaaagtaaa tgcagctgga gttattccag
    10381 ttatctttgc tagttcgttt attgctacgc caaatgctgt tttacaagca ttgagcggta
    10441 gattcggttc tgaaaactgg tacaaagtga tgatggagat ctttaactat aatacagcac
    10501 ctggtgctac gatttatacg attctgatcg ttgccttcac tttcttctac gcctttgttc
    10561 aagtaaaccc tgagaaatta gcggaaaact tgcaaaagca aggaagttat ataccaagcg
    10621 tacgccctgg taaggggact gaagagtatg tctcaagatt actgatgcgt ttaagtacag
    10681 ttggtgcagt cttccttggt ttagtggcat tgcttccaat cattgctcaa atggtttggg
    10741 atcttccaca atcaatcgga ttaggcggta caagcttact gatcgttatc ggtgtagctt
    10801 tagaaactgc gaaacagtta gaaggcttaa tgctgaaacg taaatatgtt ggattcattg
    10861 agtaagaaag cgtgttgagg tttcccctca acacacgttc tcacacattt attaggaggg
    10921 aaaacaatga acctcatttt aatggggctg ccaggcgcag gtaaaggaac acaagctgaa
    10981 aaaatcattg atgcttatgg tattccgcac atctcaacag gagatatgtt ccgcgcagcg
    11041 atgcaaaacg aaacagctct tggcctggaa gcaaagtctt atatggataa aggtgcatta
    11101 gttcctgatg aagtaacaaa tggaatcgtg aaagagcgac tagctgaacc agatacagag
    11161 aaaggcttct tattagatgg ctttccacgt acgctagatc aagcaaaagc tctggacgca
    11221 atgctaaaag atttgaataa aaaaattgat gctgtcatcg atatccatgt tggtgaagaa
    11281 atcttggtcg aacgtctagc cggccgattt atctgcagca attgtggagc aacttaccat
    11341 aaaattttca accctacaaa agttgaagac acatgtgatc gttgcggtgg gcatgaattc
    11401 tatcaaagag aagatgataa acctgagacg gttaaaaatc gtctggctat caacatcaaa
    11461 aatagtgaac caatcttggc ttattataaa gaacaaggtt tgctaaacac tattgatggt
    11521 gctcgtgaaa tcgatgctgt atttgcagat gtacaaaaaa tcattgaaaa atagcacgat
    11581 tgcccgtagc cgacttgcat tatgcagtta ctcttgtcaa gttcaataaa ttatgataga
    11641 atatgtcagt ccgacttcta gagaatcctc tagatgatcc attttgagaa ttttgaggtg
    11701 ggaactgcag tttccgccat tttatcgtgt gaaaatgcga aacaagtaca aggaggtact
    11761 gtgcgtggca aaagaagata tgattgaagt cgaaggtaca gtcgtcgaaa ctttgccgaa
    11821 tgcaatgttt aaagttgaac tagaaaacgg acaccaagtt cttgctactg tttcaggtaa
    11881 aattcgtatg cattacatcc gtatcttacc tggtgacaaa gtaacggttg aattgtctcc
    11941 atacgatctt aaccgtggcc gtattactta tcgctttaaa taattgtact ccgtaaaact
    12001 acaggaggta ttatcatgaa agtaagacca tcagtaaaac caatgtgcga acattgtaaa
    12061 gtaattcgtc gtaaaggacg cgttatggtg atttgcccag caaatccaaa acataaacaa
    12121 cgtcaaggat aattggaggt gctataaata tggctcgtat tgcaggagta gatattcctc
    12181 gtgataaacg tgtagtagtt tcacttactt atatctatgg tattggtaac actactgcta
    12241 aaaagatctt agctgatgct ggtgtatctg aagatgttcg cgttcgtgaa ttaacgaatg
    12301 aacaaacaga tgctatccgt gcagaagtag ataaattaaa agttgaaggg gatcttcgtc
    12361 gtgaagtgaa cttgaacatc aaacgtttga tggaaatcgg ttcttaccgt ggaatccgtc
    12421 atcgccgtgg attgcctgtt cgtggacaaa acacgaaaaa caatgcacgt actcgtaaag
    12481 gcccagctcg cgctatcgct ggcaagaaaa aataattctt aagtgaagga ggttaaaact
    12541 tcatggcagc aaaaaaagtg aatcgtaaac gccgtgtgaa gaagaatata gaagcaggta
    12601 ttgcacatat ccattctaca ttcaataaca ctatcatcat gatcactgat actcacggaa
    12661 atgcattagc gtggtcatca gctggttcat taggtttcaa aggaagcaaa aaatcaactc
    12721 cttttgccgc tcaaatggca gcagaaactg ctacaaaagc agcaatggaa cacggattaa
    12781 agactgttga agtaacagtt aaaggacctg gttctggacg tgaagcagca attcgttcat
    12841 tacaagctac aggtttagaa gtgactgcaa ttcgtgacgt gactccagtt cctcataatg
    12901 gtgcccgccc tccaaaacgc cgtcgtgttt aatgagtgcc gctcattttg agttttatca
    12961 gtaacgtcat tgaacaagac acttttcgtt ttgaaagggg taaagataag aatgattgag
    13021 ttcgaaaaac caagaatcgc aaaaattgat gaagaaaaag attatggcaa gttcatcgtt
    13081 gaacctcttg aaagagggta tgggactact ttagggaatt ccctacgtcg tattttatta
    13141 tcttctttgc caggtgctgc catcactaat attcaaatcg atggtgtact gcatgaattc
    13201 tctaccatca aaggtgttag agaagacgtc actcaaatca tcttgaacat taaaggctta
    13261 gcgctgaaaa tgtatggcca agaagaaaaa acccttgaaa tcgatattac cggacctgct
    13321 acagtaactg ctggcgatat tatcgttgat agtgatgtag aaattcttaa caaagatatg
    13381 tacatctgta gtgtctctga aggagctacg ttccatgctc gcttaacagt gaaacctgga
    13441 cgtggttatg ttcaagcaga tgaaaataaa aaagaagata tgccaattgg cgttcttcca
    13501 gtcgattcaa tctacacacc tgttcgtcgt gtgaactatc aagttgagaa cacacgtgtt
    13561 ggacaccgtg aagattttga taaattgacg atggagattt ggacagatgg ttcaattgaa
    13621 ccgttggaag caatgagttt gtctgcgaaa atcatgactg aacatttgga tatttttgtg
    13681 aacttaactg atgaagcaaa aaatgctgaa atcatggtcg aaaaagaaga aacacaaaaa
    13741 gaaaaaatgt tggaaatgac gatcgaagag ttagacttgt ctgttcgctc ttacaattgt
    13801 ttgaaacgtg caggaatcaa tactgtacaa gaacttacaa ataaatctga gcctgaaatg
    13861 atcaaagtcc gtaacttagg acgtaaatca ttagaagaag ttaaagcaaa attgcacgac
    13921 ttaggtttag gtttacgtaa agaagattaa aaccttttac gaaggaggga aaccaacgtg
    13981 agttatcgta aactaggacg cacatctagc caacgtaaag cgatgttgcg tgatttaaca
    14041 actgatttat taatcaacga acgtattgtg actactgaag ctcgtgcgaa agaagttcgc
    14101 tcaactgcag aaaaaatgat cactttaggt aaacgcggag atttgcatgc acgtcgtcaa
    14161 gctgcggctt tcgtacgtaa tgaagttgcc agcgtgcgtg aagaaaatga ggacatcgtc
    14221 attgaatcag ctttacaaaa actgttcaac gatattgcac ctcgttacgc agaacgtcaa
    14281 ggcggataca cacgcatttt gaagacagaa ccaagacgcg gtgatggtgc accaatggtt
    14341 gtcttagaac ttgtctaaaa tcacactaat aacatcactt tatagatgat tcttttagag
    14401 tgttatgatg ttggaagata tttttccgag tctagctcag cgctgctcct caagcgaata
    14461 tcgcttgggg agtaagcact catcataaag tgttttttta taccttcaat tacctgtcat
    14521 gacagatatg tttgaaggca taaaaaaaca ttttaagcga gaaataattg aaaattttgt
    14581 ctttttttga tagtgttagt aggaacttta ggatgaagaa ggagtaatca tggagccaat
    14641 tattgaatta gaaaagataa attataaata ccagccagat gatcttcgcc ccgcattgaa
    14701 agatgtctcc tttacaattg ataaaggtga gtggatcgct attattggac acaatggttc
    14761 aggaaaatcg acacttgcca aaacgatcaa tggattgctt ctgccagaat cagggatcgt
    14821 gaaagtggga aatcaaatat tggatgaaga aaatatttgg acgatccgac agatggttgg
    14881 aatgattttt caaaatccag acaatcagtt tgttggttcg acagtagaag atgacgttgc
    14941 ttttggtctt gaaaatcaag ggattcccag agaagaaatg ctagtgcgtg tgaaagatgc
    15001 acttgagaaa gttagaatgg ctgagtttgc ttcacgcgag cctgctcgtt tatcaggagg
    15061 gcaaaaacaa cgtgttgcca ttgccggcgt ggttgcctta cgacctgata tcattatttt
    15121 agatgaagca accagtatgc tagatccaga aggtcgtgaa gaagtgatct ctacgatcaa
    15181 gaagatcaaa gaagaaagtc aattgaccgt tatatctatc actcatgata ttgatgaagc
    15241 agctaatgcc aatcggatac tagtgatgag acaaggcgaa cttgtccgtg aaggtacacc
    15301 aaaagaaatt ttttctgctg gtcctgaact gatcgactta ggtctagatc taccatttcc
    15361 tgaaaaactg aagagcgcac tgaaagaacg tggggttgat gtgcccagtg aatatatgac
    15421 agaagaaagg atggtggatt ggttatggac atccgttttg aacaagtaga cttcacttat
    15481 cagccgaata caccatttga acaaagagcc ttatttgaca tcaatatgac gatcaaagaa
    15541 aacagttata ctgcattagt agggcatacc ggaagcggga aatcaacctt acttcagcat
    15601 ttgaatgcgc ttgttaagcc aacaagcggt acagtccata ttggagaacg agatattcag
    15661 ccggatacgg ataataagaa tttaaagccc atccgaaaaa aagttggcat cgtctttcag
    15721 tttccagaag cacagctatt cgaagaaacg gtagcaaaag acattgcttt cggtcctaaa
    15781 aactttggtg tcagcgaaga agaagcacta gtcctagcaa aagaaacatt agaacaagtt
    15841 gggctggatg aaagctattt ggaacgttcg ccatttgaac tttcaggagg gcaaatgcgt
    15901 agagtagcaa tcgctggtgt gcttgccatg aggccggaag tacttgtatt ggatgaacca
    15961 acggcaggac ttgatcccca gggcagaaaa gaaatgatgg agatgttttg gcgtcttcat
    16021 aaggaacagc agatcactat tgtattagtt acgcatttaa tggatgatgt agccaatttt
    16081 gcagattatg tctatgtgtt ggaaaaggga cgaatcgtta atagcgggga gccgcaagag
    16141 gtctttcaaa acattgaatg gctaaaagaa aaacaactag gcgtacctac tgccaccgag
    16201 tttgcagaag aattaatggc taaagggatg aactttgcta ccttgccttt gacagctgaa
    16261 gaattagcag acgctatcgt ccattatgct ggaggaaatg cccatgatga ataaattgat
    16321 atttggtcgt tatatgcctg gagattcctt gatccatcga ttggatcccc gagctaaatt
    16381 attagccagt ttttatttta tcggaatcat ttttttagca aataattggg aaacgtacct
    16441 tttgttggca tttttcacat tactttctgt cttcttgtca aaagtagatt tgaaattttt
    16501 tatccgaggc attcgcccat tgatctggct aatcctcttc actgtagctt tgcaggtctt
    16561 gtttacaagt ggcggagaaa cttattggag ttggggtgtt ttccatatca ctgaatttgg
    16621 tgtgatgaac ggcctcttta ttttctgtcg attcgtgttg atcattttta tgtcgactct
    16681 actcacgctt actacaccgc ctttggaatt atcggatgcg attgagtact tgcttcgtcc
    16741 attgaaagcc gtacggttcc cagtccacga aatttcattg atgctgtcga ttgctcttcg
    16801 ttttgtgcct acattgatgg acgaaacaga aaagatcatg aacgctcagc gcgctcgcgg
    16861 tgttgatttt ggtgaaggaa acctagttca gaaaatgaaa gcagtcattc ctttgctgat
    16921 tcctttattt gtcagcagct tcaaccgtgc ggaagatctt gcgactgcta tggaagcaag
    16981 aggctacaaa ggtggggaag gaagaacgaa atatcgtgta ttgcattggc ataatagaga
    17041 cacgatggtt atcattgctt ttgtattatt aactgtgcta ctgatctttt taagaggata
    17101 aacgttcagt gggccgctat ctattctttt cttgctgatc tgtttgcaag aaaggatgca
    17161 agcagtgtat gacaagaaat attagggtct gtggcagact aaggtcacag gcctctttct
    17221 tttatctgaa aagaaagaac gaaaaaattt tatagaaaaa tcattattcc agataacctt
    17281 ttaggaacaa aggagagaaa aacatggtac gttacaaagc aatcattgcg tacgacggaa
    17341 caaattttaa tggattccaa aaacagccaa atgggcgtac tgttcaagaa gaagtagaaa
    17401 aaacattaca aaaaatggca aatggaaaag aaatcacggt ctttggttcg ggaaggacag
    17461 atgccggagt acatgcgatc gggcaagtaa tccattttga ttatccagag gagcgtccgt
    17521 tagaacgaat gcgtttcgcg ctagataccc agtcaccaga ggatattgct gtaagacaag
    17581 tagaaattgt ttcagaagac ttccacgcaa gatatttggt caaagaaaag acgtatcaat
    17641 ttcgagtgga tatagggaaa ccacgcagtc cttttcgacg ccattatgca agttattttc
    17701 cttacccact tgatttggaa aaaattcagc gggcgcttcc tgatttatta gggactcacg
    17761 atttcacctc tttttgtgca tcaggaagct cgatagagga taaaatacgt acgatctacg
    17821 aggctaagat ggaggtaaat gaaacaaaag acgaattgtt gtttacattt aggggaaatg
    17881 gcttcttgta taagatgata cggatcttag taggaacgct tttgaaaatt ggcaatggcc
    17941 gattgcctga agatagtatc ccagatatta ttgcgaaaaa agatcgtaat gcagcaggac
    18001 ctacagcaca ccctgaagga ctttatttgt atgaagtgaa atatgaataa gaggttatga
    18061 tagaagtggt cagcttcaag aaataagaag gtatttacga aaattacttc tcaaaatttt
    18121 gcaaaatttc ggcttatttt cgaagaagct acttctggaa caccgtttaa gaaagaggtc
    18181 gtgagcctgt catttaactc tgagtcacaa agagcaattt caaaaaacag cttctcatct
    18241 ttgatgaata tcgtgacttg tggacgaggc gttgataagt gaatcatctt tttgttacct
    18301 attttttctg taaccaaaaa acgatggaac gttgttttga ttgcccttgg tgcggacagt
    18361 ctgaacaggt tccatcgttt ctttattttc tacgtcttct tctgtgtgtg tttcgtggtt
    18421 gttcttctat tgctggatca atcgtgccat aaaaggggcg attgcggtca aggtaccaga
    18481 cataaagaat aaacaatgca atacatagga caaaaaggat tgcacctatc gtaaatcctt
    18541 caggcaagta actgaaagtg acagtatgtt tacctgctgg aacttttatc atcaagaatg
    18601 cgtctttgaa attgctgacc ttgactggtt tcccatcaat tttagctttc catcctttgt
    18661 cataaggaat agttgtcacc aacatggaat cttcagcggt atttacagtc ccagaagctt
    18721 ttctgccagt ggcttccatt tcgacacctt tttctttgat ctgattcatt gcggcttgat
    18781 aggctacaac atctagacca acgactttag gctccatgaa acttatttct ttcgtcccat
    18841 aaaaacttgc agtaaatgtc actgttgtct cttgaggata atagccaaga tcatagtatt
    18901 gaccagaaat gttgatttgc gtttttcgcg atgtaccatt gacagtgatc gtcgcactag
    18961 aactttctaa ttgcgcaaaa ttggttggga acaaacttaa gtaagcttgt gtatttgcag
    19021 gcacatggac ttcccaagtg agctcttttg gctggttatc tgctgtttct gagtaagtga
    19081 cgccagtcgt tgtctttgtg atcgtcgtat tcaactgatt cttcaaagta ggtgtataga
    19141 atgtaaaata ctgttcattt agaccagaca atgtattgat caagtttgtc tgactggtca
    19201 aattatctgt cactggctgc tcaacatcat taacggacaa cggtgcagta aatgctagtg
    19261 gcaatgcatt gacattctga tacagtgtat agtcgccgct ttgaccagct tggcggaagc
    19321 catatttact gaacgtgctt tcgtttttag aaatgttata tttgattcct gtaaacccat
    19381 ccatcagcaa agtattattg ttataacgga tattcaaatt tgtccctctt gaacggaaac
    19441 ctaatttatc caggtaagag gaagaattac gatttcttat agaagaaaac aaactgatac
    19501 cactgtaacc atagttgatc gaatcgtttg cagatactgg atccagattt tccaagcggt
    19561 aaaacgagtc ggaatctttt tttgtttcat ttacaagagc tttcaagtca ggataaggat
    19621 cagtatataa actgcgggaa gcataattcc aatcatcaag aatgccatgg atcatactgt
    19681 tcgtattgac cagtgcttca gcagacatga tcaataataa caatatactc agatgattga
    19741 atgaaagttt tttatgctga taaaatccca cagcaaaagc ataaatccct aagaaaacca
    19801 ctgtcaatac aaaggaagtc atcgtcacat aggtgtagct tccttcaggt ttgatgcccc
    19861 atgccaccgc aaagagagca gctacgacca aaatgattcc taacaacagc ccaccatcgt
    19921 cttgttctat cttttcccat ccttttcctg caagcaggag cactaagaaa gagaacagat
    19981 aggcataacg gaataaaaac atattcggtg catgcatacc atgccagaac aaattcaatg
    20041 gaacaagata aaaacttgcg ataagtatgg cgaaaagact gccgtacaaa aatttatttt
    20101 tcaacggtac tttccgactg gcaaaataaa acagacagag gactaatggt agcagacctg
    20161 cgtaaacgaa cggaatcgat ccgtattttg tcgtgtcata aacaccaatc atatttttca
    20221 tgattagatc cagataagaa gtcgcttctg ttttcaacgt agtgatctga ctcagtgcct
    20281 cgccatttga ccgaagatcc agcactgctg gcaatacaat gatcattgaa gcgccgcctg
    20341 ccagtaaaga agtgatacca taaggaacaa tcgttttttt atattctgac cagtttgtca
    20401 atagacgggc gataaaatat aagaaagaaa atacgccaat cataaaaccc atataaaaac
    20461 tggataaaaa caagagtaaa taactgataa ataaaagttt cggccgttta agatccataa
    20521 cacgatgaat ccccaaaatc actaatggaa gataaacaaa tgcatccagc cacatgatga
    20581 tctccgaatg tgcagtgata aatgagatca atgcgtaact gacgctaagt gcaacatgcc
    20641 cccagcgagg aatcttgaac gtacgtgcaa gaaaccaaaa agccaatccg gcacagccga
    20701 ccttaagcaa agtcagaaca tacagtgcat ctggcatcat ctggtttgga aaaaagaaca
    20761 ccagtggcgt gaagatcccg cctagatagt aagaaattaa agataaataa ttcaatccta
    20821 gagaagcatt ccatgtataa aaaatacttt gctttccaag aagaacattt cggaagctgg
    20881 catgaaaatt agaaaactgt gaaaaggcat cacttgccaa aatacttctg ctgcttccag
    20941 gatagattcc gatacttaga taaacaagtg ctaaaatcaa aaacggaatc aggaaactag
    21001 ctgctgcgta gcgtccgttt tctctaaaga atgactttaa attttttttc atatttattt
    21061 tccaccaaat ttctatgaag ttgtattcag tttatcatat ccttgttttt ctctgcttaa
    21121 aaagagtcta gttttcacaa aaaaataaaa tttagaataa ataacttcat aatttgttcg
    21181 tataacaaaa ataaacgcaa aaaaagggta ggaatcaaaa gtcccaccct taaaaatttt
    21241 tattaaataa aaaaccgttc actatctgaa cggtccaagt atcattcaat taaacgcgtt
    21301 caacttttcc tgatttcaaa gcacgagttg acacccaaac ttttttaggt tttccgtcga
    21361 ccataacgcg aactttttgt aagttaggtt taacagtacg ttttgttgag ttcatagcgt
    21421 gtgaacggtt gtttccactt tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg
    21481 taatttcctc ctttgccttg atttggagca atagaataat tcagctcata ccagactaac
    21541 atatcatata gaatgggaat ttgcaagtac attttcatag atacaattga caattgagaa
    21601 gaataattgt aaattaaaca aggttatacc tgaaattttg caaggttttt gagtactttg
    21661 ggtaactgcc ttttatttca agttgcgcta tgataaaata tgatagaaga aaaatgggag
    21721 ttttttaccc gttaaggagg ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc
    21781 attgaaatta ccaatgatgt aattgcaaca gttgttggtg gcgccgcgac agatgtgttc
    21841 ggtgttgtag gaatggccag caaaaatcaa attaaagata atattactga gattttgcgt
    21901 aaagaaaatt actcaagagg agtagttgtc cgccaagaag ataatggtat tgctgtagat
    21961 gtttatacga ttatcagcta tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa
    22021 aaagtgaaat acaatctaga ggcattatta ggcgtaactg ccaattcagt taatgtcttt
    22081 gtacaaggtg ttcgtgtact gccagactag gcaggagact ggctggtaac tcagcagtcg
    22141 atctgaagga ggattatcta ggtgagtgta acagaaataa gtgcaagcca gttccaggaa
    22201 atggtccagg caggtgcgaa tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat
    22261 gtattccctg tgccagatgg cgatacggga acaaatatga atctatctat gactagtgga
    22321 gctaaggcag tagtagattc aacctcagaa aaagtaggag aattagcagc aatgctttca
    22381 aaaggattgc tgatgggtgc gcgcggaaat tccggcgtta ttttgtctca attgtttcgt
    22441 ggattttcta agcaaattcc agatgttgtc tcattaaatg cttctgatct tgctgcagcc
    22501 ttcactcatg gagttgaaac tgcgtataaa gcagtaatga aaccagtaga aggaacgatt
    22561 ttgacagtag ctagagaagc agcgaaagct ggagaaaaga aagcaaaaag tactgatgat
    22621 gtcgttgaag taatgacagc tgttgtaaaa ggagcaaagc gtgctttagc taaaactcca
    22681 gacttgcttc cagtcctaaa agaagtcggt gtcgtagaca gtggagggca aggactgctg
    22741 tttgtttatg agggcttttt aagtgcattg aatggagaat tccaagcgga tgaaacatat
    22801 gaaccttctc cagcagaaat ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa
    22861 ggtcaaatgg cgacagaaga tatccatttt ggttactgta cagaaatcat ggtaaaaatc
    22921 ggagaaggac ctacagtcga tagtacattc gattacgaag aattccgtaa ctatttagat
    22981 ggtataggag attctttact tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat
    23041 acagaaaacc caggagaagt cttgaattat ggacaaaaat tcggttcatt agtcaaaatc
    23101 aaagtcgaca acatgcgctt gcagcatgag acgattttgg aacacgatga agaagtgaac
    23161 gagtttgcga aaaaagaaat accacgtatc ccgtatggta tcgtagcgat cgctgctggt
    23221 aaaggcgtcc aagagctgtt tgaaagttta ggcgctaatt atgttatcag tggtggacaa
    23281 acaatgaatc caagtacgga agacattgtt aaagcgattc aagaagtaaa cgcagataaa
    23341 gtgattgtct tgccaaacaa taagaacatc ttcatggcag ctgatcaagc agcagaagta
    23401 gcagatatcc cagtagcagt tgttccttca agaacgattt cccaaggatt gacagctatg
    23461 ctttcattca atgatcaagc ttctttagaa gaaaacaaag aaacgatgac agaaatgttg
    23521 tctagcgttg tgagcggtca agtcactcac gcgatcagag atacctcaat tgacggtgta
    23581 gagatcaaag aaggagactt tttgggcatg atcgatggaa aaatcctgat ctctaaccca
    23641 gatatcacag caacagcgtt aagtacacta gaacaaatga tcaatgagga cacagagatc
    23701 gtaacgatct tggcaggtga tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa
    23761 ctaacagaaa aacatcctga tttggaaatc gagatccacc aaggagatca gcctgtctat
    23821 ccttatctat tttctgctga ataatttctg tgtcagaata tctttctaac acagtattca
    23881 ttcataaaag gccttcggtt agtgatcagg tatgatcgct gaccaagtcc tttttttgtt
    23941 aaaggaggga ggaaaaattt atgcgttctt tagatgatcc aatcactatg ctggcaggag
    24001 tcggagaaaa aagagcagct agtcttgcca gcttgggcat ccaaacgatt gaagacttac
    24061 tgacttatta tccttttcgc tacgaagata ttcaggaaag aaatctaaac gagatccagg
    24121 atcaagaaaa ggttactttg aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg
    24181 gttataaaaa aagccgattg caatttcgta tgatgcaaga acatgatgtg ttcaacgttt
    24241 ctttttttaa tcaaccttat ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat
    24301 acggtaaatg ggatgcaaag cgtaaagcct tgaacgggat gaagatttta ggttctcaaa
    24361 caatggatga cttttcgccg atatatcacg tcaacaaatc aattcgtcaa acgacattag
    24421 ttgatctaat caaaaaaggg tttcaagaat acggcacatt gattgaagaa aatctgccaa
    24481 acaaccttgt ggagaaatat cgactgcttg accgagcttc tgctgtaaga agtatgcatt
    24541 ttccaaaaga ccacgaagaa aaccatcaag ccaaacgacg tgtcgttttt gaagagttct
    24601 ttttatttca aatgcgtctt caaggattga aaaaagcaga aaaagcagaa acgaatggtt
    24661 tggagatcct ttatgatgtc caaaaattga aacaatttac tcaaaagcta ccttttgaac
    24721 tgacaaatgc acaaaaacgt gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc
    24781 atatgcagcg acttttgcag ggagatgtag gtagcggaaa aacagtggtt gccgcgattg
    24841 cgttatacgc taccgttaca gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct
    24901 tggcacaaca acatatggaa agcttgcaac agctgtttga tcccaatgaa gtaaccatcg
    24961 cattgattac ggggtcaacg aaagcaaaag aacgacgtga gctccttgaa aaactagagc
    25021 aaggggaaat taacgtcgtg atcggcacac atgcattgat ccaagatgga gtcgaatttc
    25081 agaatttagg tctagttatt acggatgagc agcaccgttt tggcgtgaac cagcggaaag
    25141 tacttcgtga aaaaggctgg cgaccagatg tcttatttat gacagcgact ccgattccta
    25201 gaacattagc tattacagca tatggtgaga tggatgtatc tatcattgat gaacttccag
    25261 ctggacgtat cccgatcgaa acacgctggg taagaacacc tcaattggac agtgtactgg
    25321 attggacgaa aaaagaactg gcaagaggac atcaaatgta tgtcatctgt ccgctgattg
    25381 aagaatcaga agcattagat gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac
    25441 tatttgcacc aaaatatgaa gttggcttgt tacatggtaa aatgaagaat caggaaaaag
    25501 aagtaatcat ggaagccttc aaagacaacc agatgcagat attagtttcg actactgtaa
    25561 ttgaagtagg ggtaaacgtg ccgaacgcga ccgtcatgct gatcatggat gcggatcgat
    25621 ttggattggc acagctgcac caacttcgtg gacgtgttgg acgcggaagt gatgcttcct
    25681 actgtatctt agttgctaat cctaaaaatg aactaggtgt ggaacggatg aaaatcatga
    25741 cagagaccac caatggtttt gtactaagcg aaaaagatct ggaattacgt ggtcctggtg
    25801 aagtatttgg cttccgtcaa tctggtctgc ctcaatttgc gattgctgac ttggtgacgg
    25861 atggaaatgt tttggaggta gccagagaag aggctgcagc cctttggcaa ataaaggatt
    25921 ggcagatgct tcctgagtat cagcctttag cgcaaagcct ccaaatagaa aatcaggata
    25981 atcgttattt cgattagcag actgtgctat actttatact gatgacggaa aaaggagtgg
    26041 aaacaatgaa aattgccgta gatgcaatgg gcggagatca cgcacctcaa gcaattgtag
    26101 aaggcgtggc tttagcgcag caagattttc cagaagtaga attcttactt tacggaaaag
    26161 aagcagaaat caagaaatac ttaacaaatg aaaaaaacat cacgattatc catacagacg
    26221 aaaaaatcaa tagtgatgat gagccagtaa aagcaattcg acgaaaaaag actgcatcaa
    26281 tggtccttgc tgcacaagca gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga
    26341 atacaggcgc gctactagca gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac
    26401 gccctggctt gatgtctacc ttgccagtag tagggaaaga aggtgccggt ttcgatatgc
    26461 tggatcttgg cgctaacgca gaaaacaaac cagaacattt gttgcaatac ggtattttag
    26521 gttcttttta tgcacgtaaa gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca
    26581 acggaacaga agcaacaaaa ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga
    26641 atgaaacaag cttgaatttt attggaaacg tagaagctcg tgagctactc aatggtgtgg
    26701 ctgatgtagt ggtcacagat ggatttacag gcaacgctgt tttgaaatct attgaaggaa
    26761 cagcaatgaa tatgatgaat ctattaaaat ctgctattct aaatgaaggg atcaaaggaa
    26821 aaatgggcgc tatgctttta aaagacggct tacgttcttt gaaagcagaa atggattatt
    26881 ccaaacatgg cggtgccgtt ttgtttggct tgaaagcacc agtcattaaa actcatggag
    26941 caacaggccc cgatgctgtt cgctatacga tccgccaaat ccacacaatg cttgagacag
    27001 atgtagttgg acaattagtc gaacaatttg aaaaaagcga agaatagtat ttggatatct
    27061 gaagcgatcc gttccattga aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag
    27121 ccatggtgta ggtaattgac aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa
    27181 gaagtattta acaaagtagc gaaaattatt tcaaatcatt ttgagataga taccgataaa
    27241 gtgacggatg aattgaacat caaagatgat ttaaaagctg attcaattag tattatggaa
    27301 ttcgttttag agcttgaaga tgaattcggt acggaaattt cagatgaaga cgctgaacaa
    27361 attgaaacag tcggtggcgc agtagattat atcagcagcc atcttaaata atttcaaata
    27421 aaagcaaaga aggataaaaa gctgcatgca gctttttatc cttctttttt taatcttttt
    27481 gacacgtaaa agtcattttt ctgataattc tggcgataaa cagaaattat gttgcaaagt
    27541 aaagcggttt tctatataat tattaataat tcattacaca aagataagaa taacctttgt
    27601 tataaaacga tttattctgt gtaatgtcct tttttattaa gaaaaacttc catttaggaa
    27661 gcagagaggg gtattcgatt gtccgataac caattattag aagttcagaa cctacataca
    27721 ggattccgac tcaaagatga ctattacgat gcagtagatg acgtttcatt tactttagac
    27781 aaaaacgaga ttttagcaat cgttggggaa tctgggtgcg ggaaaagtac cttggctact
    27841 acgattatgg gattacttga tcctaataac acaaaaatta caggtgagat tttatataac
    27901 gatctgaatt taatcgacct gaacgaaacg ctctataata aaatccgcgg aaatgatatc
    27961 ggaatgattt tccaagatcc gttgtctgca ttaaatcctc tcatgagaat cgaagaccag
    28021 atcaaagaag gactttccta tcacacaaag atgaatgcag aacagcgtca agctcgtgca
    28081 ctagaattgc tagaacaagt agggattcct aatcctgcga gagttggacg ccaatatccc
    28141 catgaactat caggcggtat gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa
    28201 cctccaatcg tcattgcaga tgaaccgacg acagccctag atgtaaccat ccaagcacag
    28261 attcttgatt tactgaaaga ccttcaggaa gaaacaaaaa cagggatcat cttgatcact
    28321 catgacttag gagtcgtagc agaaatggct gatcgagtgg cagtgatgta tggcggacag
    28381 ttcgttgaag tagcaggtgt aaaagaactg tttgatcatc ctaagcatcc ttatacacgc
    28441 tctttactga actctatacc acaagaagga aatcatgatg cagaactcca tgtgatcgaa
    28501 ggtgtcgttc cttctctgaa aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt
    28561 ccatggatac cagcaagcga tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac
    28621 cacttggtac gttgctcctg ctataagcat ttccacttta gagacgaaaa aggagaggtg
    28681 tagatgacag aattaatcac aatcaaagac ctgaaagttc attaccctat tcgcagtgga
    28741 ttcttcaatc gagtaacgga tcatgtatat gctgtagatg gtgtggattt tattatcgaa
    28801 aaaggaaaga catatggttt agtgggagag tctggctctg gaaaatctac tacgggaaaa
    28861 gccgttgtgg gattagaaaa ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta
    28921 acgaagcgaa gcaaccgcaa aaaaatgggt tataacaagg atgtgcagat gatcttccaa
    28981 gattcaatgt ccagtttgaa tcctaaaaag cgagtgttgg atatcattgc tgaacccatc
    29041 cgaaattttg aacggttaag cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat
    29101 atcgttggga tgccggaaga tgcgctatat aaatatcctc atgaattttc aggcggacaa
    29161 cgtcaacgtc taggagtagc ccgtgctgtt gctaccaatc caaaactgat cgtagccgat
    29221 gaacctgtat ctgctctgga tctatctgtt caagcgcaag tattgaattt catgaaacga
    29281 atccagcaag aatacggcct cagctattta ttcatttcac atgatttagg tgtagtaaaa
    29341 cacatgtgcg acaatatcgc aattatgtac aaaggtcgat ttgtagaaat cggtacaaga
    29401 gaagacattt ataatgaccc gcgacatatc tatacgaaac gtctgctttc agctattccg
    29461 caaatcgatg tagaaaatag ggaaagccac aaagaaaatc gacgaagagt agaacaagag
    29521 tatatccaaa accaaaaaga atactatgat gcgactggtc gagtctacga tttgcgtacg
    29581 atcacaacta cacacaaagt ggcgttgaaa gatggaggtg caagctaatg tggaaaacga
    29641 ttctgcgacg tgttttattg atgatcccgc aagttattat tttaagtgtt ctgatcttct
    29701 tattagccca agcgatgccg ggggatccat ttaccggttt gatcaatcca aatcaggatc
    29761 cggcagtgat cgaacagatg cgacaagcag ctggcttgaa tgacccatgg tatgtccagt
    29821 acttccgttg gatcggaaat gctttgcaag gcgattttgg tcaaagtttc ttatacaaac
    29881 gctctgttgc tgacttgatc ggcgaacgga tcatcaacac tttatatcta tcgatcttga
    29941 cagttgtcct tacttatttg attgctgtgc ctctggggat gcttgctggc cggtatcaaa
    30001 attcaatctt ggataagatt gtcgtaatct acaacttctt tagttttgct gttcctttat
    30061 ttatcttcgg cttgatcatg ctatttgttt ttggttatcg tttaggctgg ttcccaacaa
    30121 gtggatcaca aacactaggt ttgcaaggtg gatttatcac tcaatggata gaccgtttga
    30181 aatatattct gttaccatca attacccaag catttttggc gactgccgtc acaatccaat
    30241 atctgcgaag tgaagtaatc gattcgaaat cgctcgattt tgtcagaaca gcccgttcca
    30301 aaggggtacc gacgaataaa gtattcagtc gacatatttt ccgaaatgca gcgttgccga
    30361 tggcttctca aatggggtat gaaatcactt cgttgattgc tggttctgta gttatcgaaa
    30421 agatttttgg ttatccggga gtcggaaaac tatttattga ttccatcggc caacgggact
    30481 ataccgtgat cacatcctta gtattgattt taggaatcgc gacgctagtg gggacattac
    30541 tttcagatat catcatgagt atcgttgacc cgcgtattcg gattcaataa aaccaatcag
    30601 aaaggagaat ggatcgatga gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc
    30661 tatggggata cgaatgattg ctcgagaatt taaaaaagat aaaattgcta ttttttcatt
    30721 aggtttgcta gtggttttat tattagtgat ctttatcggt gcgatgctga ccgatcaaga
    30781 caaagtgatg tatgttagta tcttcgacaa atacgctgca ccaggaacag tttcgacaca
    30841 aggacaaaag ttcattctgg gagcagatga aggcggacgt gatgtattag gacaattgat
    30901 cataggtgct agaaactctg ttacgatcgg atttgcgatc acgatcctta cttcgatcat
    30961 cggggttgga ttagggatca tctctggcta ctacggaggg atcattgaca acatcttgat
    31021 gcggatcgtt gattttatca tgattctacc gatcatgctg atcattatcg tcttcgtatc
    31081 gattatttcc agatacaatg tctggtcctt tatattcatc atgagtgcat tttattgggt
    31141 agctaaagcc cgattattcc gaagcaagac attatctgaa gcaagaagag attatgtcag
    31201 tgcctcaaaa acaatgggaa ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa
    31261 tctaagttca ttaatcatta ctaatttgac gatgaacttt gcggcaaaca tcggtatcga
    31321 gacaactttg actttcttag gtttcggctt gccggcaaat gtacctagtt taggtacatt
    31381 gatcggttat gcaagtaacg gagaagtctt agtgaatcgg caatggatct ggttacccgc
    31441 atcaatcctt attttagttt tgatgttgag tatcaattat gttggacaag cattcaagcg
    31501 ttctgcagat gcgcgccaac ggttaggcta gtatagaagc gaagggggaa ataggaatga
    31561 agaaaacgat ttttggattt gcagcgctga tgtctgctgt cgttcttgca gcatgcgggg
    31621 gcggaggtac agatacctct ggaaacaact ctggaggcaa cggcaataac aaagaggaat
    31681 taacttttcc aattgcaaca aaaaataatg atgatgcaat cgaagacggc gaattagaag
    31741 ctgcggtcgc aacggacagt cagtttaaag gattgttcca gtgggagttt taccaagatt
    31801 catatgatgc agcttttatg gctccttctc atgaaccgct atttgcaaac gatgacgatt
    31861 tcagaatcac agacgacgga gctgcaacgc ttgatctaga tgaagatacg aaaaaagcga
    31921 caatcaaagt aaaagacaac gtcaaatggt cagatggtga agatgtaacg gcggacgatg
    31981 tgattttccc ttacgaaatc attgggaata aagattacac tggtatccgt tatgacgaca
    32041 ctttccgtaa catcgtaggt atggaagaat atcatgatgg aagtgccgac acaatctccg
    32101 gaatcaaaaa aatagacgac aaaacagttg aaatcgaata taaagaagta aacccaagca
    32161 tgcttcaatc gggtggtggt atctggtcat atgcagcacc aaaacatacg ttagaaggtg
    32221 tagcaatcaa agatatggaa tcaagcgatc aagtacgtaa aaatccagtg acttttggcc
    32281 cttattacat gagtaatatc gttgcaggag aatcagtaga atacttgcca aacgagcact
    32341 actggaatgg tacgcctaaa ttgaaaaaga tcacgatgaa atctgtaccg atggcaagtg
    32401 caactgaagc attgaactct aaattatatg atatgatttt ccaaatgcca acagatactt
    32461 acgataccta taaagaaatt gctggctata caaacttagg ccgtgaacaa acttcttata
    32521 cttatctagg attcaagtta ggtaaatgga atgcagatac aaagagtgtg gaatacaatc
    32581 cagattcaaa aatggctgat aaatcattac gtcaagcaat gggctatgca ttagataata
    32641 atgcagtagg tgaacgtttc tatgcaggtt tgagaagcaa tgcgacttca ttgattcctc
    32701 cagtattcca gtcataccat gatgatgaga tgaaaggatt cacacaagat ctagacaaag
    32761 cgaaaaaact attagatgat gctggctaca aagatgtgga tgacgatggt ttaagagaag
    32821 acaaagatgg aaataaacta acaatcaact ttgcttcgat gtccggtggg gaaacagcgc
    32881 aaccattggc agattactat atccaacaat ggaaagaaat tggtttggat gtccaataca
    32941 caacaggtcg tctgatcgaa ttcaattctt tctatgataa attagaaaac gatgatcctg
    33001 aaattgatgt ttaccaagct gcttggaata caggaactga tccaaatcca agtggactat
    33061 ggggaccaaa tgctgcgttc aactacactc gttatgaatc agaagaaaat acaaaattga
    33121 tcaacgatat cagttcaagc aaagcatttg atgaagagta ccaaaaagaa gcatatcaaa
    33181 aatggcaaca atatgcattt gaagaagcat ttgcgattcc aacgttgttc cgtaatgaag
    33241 tattgccagt caacgaccgt gtcaaagact gggattggtc ttatgatgta ccaaacccat
    33301 gggcaaatgt ttctgttaca gcagattcac gttcataatc actaaaaatg accgaaaaag
    33361 ggcgatgtcc tttttcggtt ttttgatatt tttctgttta tttctctaat attcaggtca
    33421 aggcgctgat ttcatgactt ctccaataaa cggtgttcaa agtccagttt ctcggtatta
    33481 agtcaaattt atgcaaaaat atggaaagcc attttcacaa aattttttct tcatactcga
    33541 aactaaacga atttttcaca acttctcgtc aatcactagg attattaaag ctttacttac
    33601 cttttgaccg aaccatttca aatttgacaa aaaaccagta taataaggaa gtatcgaaaa
    33661 aatatccata aaaggaatgt ggaaaatgga caaccagctg acaaaagaac taaaagaaaa
    33721 ctataacatc gtttttcacg atctaaattt gcttgaacaa gcttttaccc attcatccta
    33781 tgtgaatgag catcgcaatc tgcaattatc ggataatgag cgacttgaat ttttaggaga
    33841 tgccgtttta gaactgatgg tttctcagta tttattccgt ttatatcctc atttgccaga
    33901 aggaaaattg acaaaaacac gagctgcgat cgttcgcgaa gacagcttgt cgaaatttgc
    33961 caaagaatgt cactttgatc aatatgtttt gttgggcaag ggagaagaga attcaggagg
    34021 acgtacgcga ccagcattgc tttgcgacct attcgaagct tttttaggcg cgttatatct
    34081 tgaccaggga ttcgacacga cccatgcatt catcgaaaaa gtgatttttc ctaaagtcaa
    34141 agcaggtgct ttttcacatg agatggatca taaaacaaaa ctacaagaag tcttgcaaaa
    34201 atcaggtgat gtatcaatcg aataccgatt gatcaatgaa gaaggtccag ctcatgaacg
    34261 agtattttgg atcgaagttt atgtagatga tcaattgatt ggcactggac aagggaaatc
    34321 gaaaaaatta gcagaacaag ctgcggcgga aaatgcattg gcagcactgt aaaagtaagt
    34381 gagggaaagc tttgtatttg aaacgaattg aaatagccgg ttttaaatca tttgcagaca
    34441 agacagtcat tgattttgaa aatagcgtca cagcagtggt tggaccaaat ggcagcggaa
    34501 aaagcaatat tacagaggct atccgctggg tattaggaga acaatctgct aaaagtctgc
    34561 gaggcggaaa aatgccggat atcatctttg ccggttccga tacccgtaag cagctgaata
    34621 ttgcagaagt cacagtgatt ttagacaata gtgatcatta tctgccattg gagtacaatg
    34681 agatcagtgt aacccgccgt tatcgacgga ctggggaaag cgagtttttc atcaataaac
    34741 aaagctgcag attaaaagat atccaagaat tgttcttaga ttctggatta ggaaaagaat
    34801 cgttctcaat catttctcaa ggaaaagtag aagcgatttt cagtagtaaa ccggaagacc
    34861 gtcgtgggat ctttgaagaa gcagctggtg tcttgaaata caagcagcgg aaaaagaaag
    34921 cagaacagaa gctttttgaa acagaagaca acctcagccg cgtccaagac atcatccacg
    34981 aattggaaga acagttaact cctttggccg cccagagtga ggcagcaaag gagtttttac
    35041 ggctaaaaga aacactgact caaaccgatg tctctttgat ggttgctgaa atcaagacag
    35101 caaaaaaaga ttgggacaac aaacaagcac agcttgcgaa attcaatcta gaattaggca
    35161 aactatctga gtcgatccaa gaacaagaat ccattttggc gaagcagcgt aaagaaaatg
    35221 cgcaagccga tcgtctgatc gaaaaaaatc agcaagtatt attagatctt tcggaaaaac
    35281 tgaagcagac agaaggacaa aaagatgttt tgcaggagcg gacaaagcat acacaaaaaa
    35341 gctcgcaaga atatcaaact tcattagcag aagcacaaaa aaaggttaaa cattttgaaa
    35401 agcttcaaga aagcttgatg aaagcagcag cagaaaaaga aacagagatc caaaaagctg
    35461 aagcaaatct cataaaaaca cagcaagaat tagaaaaata ccaaaaatca acgaaagaat
    35521 tattggcaga attaagagat caatatgttg atttgatgca agaacaagca gctgtaggaa
    35581 acgaactgaa gtatctagaa cgtcaatata tacaagaaac agcaaaaagc aagcagacgt
    35641 tagccaagca atcggaagta gaagcatcag tagaccgatt gatcttacaa aaagaagaat
    35701 tgacacaaaa gcaggcgcag ctaaaatcat ctttaactga aacaaaagag aagttagaaa
    35761 tgatccaaca aaacgggaaa aagttccaag aagcattagc aaaagaacag cctaaaatgt
    35821 atcaattaat gaatcaagtc cagcagctac gtgctcgtaa gaaaagcctt caagaaatcc
    35881 aagaaaacta ttttggtttt taccaagggg ttcgattggt cttgcagcat aaacagcagc
    35941 tttcgggtat tgtcggagca gtggctgaac tgatcgatgt tcctgcagat ttcacgttag
    36001 ctatcgaaac agctttaggt ggggcagccc agcatgtcat cgttgaaaat gaaaaagatg
    36061 ctcggcaagc catcacgtat ttgaaacagc aaagaggagg aagagcaaca ttccttccac
    36121 tgacgacaat caaaccaaga caattaccgg ctcatatatt gacacaagca gcagctgtag
    36181 aagggtttat agggattgcc agtgaacaag tcagttatcc cgatcaaatc caaactgtgg
    36241 ttcaaaacct gctaggaacg atccttttag ccaaagactt aactagtgcc aatgcaatcg
    36301 cgcaaacgat ccgctatcaa tatcgagtgg tttccttaga aggtgatgtg atgaatgccg
    36361 gaggatccat gacaggtgga gcgaataaac gaggaaacca aggcagtttg tttgtacaaa
    36421 atcaagaatt gaaacagttg actagtgaat ttgaagaagc agataaacaa ctccaagcac
    36481 aagaaaaaaa agttcaggag ctgcaacaag aaacagctcg tttagccgaa gaacaagaag
    36541 ttttgcgtac acgaggcgaa caattacgtt ttgaagaaca agaagcgaca aatcagctac
    36601 aaaacatcat aaatgaactt gaacgttttg aaaaagaaaa gcaaatctca acttttgaga
    36661 cacgtgaact gcagcagttt atcgaagatt acgaaaagca aacgaacgaa ttgaaagaca
    36721 aacaaacaga tcttgaatcg caacgacaaa aaatcgacga agaaatcaaa tcgttaagtc
    36781 aagaaagcga ccagatggaa gccagaagag cacaagtaca aagtcaaaaa gcacaagaac
    36841 aagcagatct tgctgtcttg aaagagcagt ttaatcatct gcagatccag ctccgcggtg
    36901 cccgagtcca aaaagcagag gcaaccgaac gtcaagaagc gatagaaaag cagttggcga
    36961 cattgacagc agacttttct gatcatgaag tcacagaaga aagtttggaa aaacaaatta
    37021 acgaattatc tgctcagcga gaaacattaa aagccgagtt ggcaaaagcc aaagagcagc
    37081 gagatagaag gcaaaaggag atcgataagc ttgaagcagt cttggcagag cgtaatcgtg
    37141 agcaaaaagc acgactgtcg gaacaatcca aattagaagt ccaaaaagac cgagctgaaa
    37201 tgattttaga taatcatttg acctatctgc agtcagaata tcagctgaca tttgagaaag
    37261 cttcccaaga ctatcaagaa acaaccgata tcgaagacag tagaacaaag gtttcatcct
    37321 taaaagaaca gattgaaaaa ctgggaccag taaacttaaa ttcaatcgaa caatacgaac
    37381 aagtcagtga aagacataca ttcttagcaa cacagcgaga tgatctgtta gcagcgaaaa
    37441 accaattgtt tgaaacgatg gatgagatgg atgatgaagt gcggacaaga ttcaaagaag
    37501 tatttgaagc tatccgtcaa gaattcaaaa ttgtctttcc aaatatgttt ggcggcggta
    37561 aagctgaatt agtactgacg gaaccaactg atttgctgaa aacaggtatt gagattgaag
    37621 tacaacctcc tggcaaaaaa ctgcaaagtc taagtttgct ttctggagga gaacgagcac
    37681 ttacagccat cgcgttgctc ttttccatta tccgtgtctg tcctgttccg ttttgtatct
    37741 tagatgaggt agaagcagcg ttagatgaag ccaacgtgaa acgttttggt cgttacttga
    37801 gcgatttcca agatgacaca caatttatcg tagtcacaca ccgcaaagga acgatggtcg
    37861 cagcagatgt actgtacgga gtgacgatgc aggaatccgg tgtatcaaaa atcgtttctg
    37921 tacggatgga agatatcaat gaagaggcga aaatcaacga aacgaaagtg taggaacgaa
    37981 aatgatcaaa ttagtagcaa tcgatttgga cggtacatta ttaaatgaac aaaagctgat
    38041 ttcagatgag aataaacaag cattagcaca agcaaaacag caaggggtca agatcgttct
    38101 atgtacagga cgccccttag ctgcgatggc gcattatctg caagaattag gactggtaga
    38161 tgaaggtgac tacagcatca ctttcaacgg cggtttggta caaaaaaatg atactggtga
    38221 aatcatggaa aagaaagtga tggaagtatc agatatccaa cgcttataca aactggctca
    38281 gcaattggat ctgccactag atgttttgtc tgacaatgtg gttttacagc tgcctagtgc
    38341 cccaaggaag caatccttgt acaatgtgtt gaataagctg ctgcaattcc aaccagcgga
    38401 tataagcgat attacagatg aatttgtgct taataaggca gtaatcgctt atgaccaaga
    38461 agaattagat cctaaaatca aagaaatacc agcagaattc catgaaatgt atgagatcat
    38521 caaaacaaga agtatgcttt tggaatttat gccaaaaggt gttacaaaag cttatggtat
    38581 ttctttattg gcaaaagatc ttggtttgaa acaagaagaa atcatggcga tcggtgatga
    38641 ggaaaatgat ttaccgatga tccaatatgc tggactaggc gtagcgatgg agaatgctgt
    38701 gcctttcgtc aaagaagcag cagatttcgt gacagccagc aatgaagaaa atggcgtagc
    38761 caaagtgatc caaaaatttg tattagagta gggggagtca aatgggattt tttgataaaa
    38821 tcaagcgtgc ttttactggc gaagagaaaa cagaagaagt tgaagtacag gagaagtacg
    38881 acaagggttt agaaaagacg cgtaaaacat ttggtgaacg gatgaatgag ttgtttgcca
    38941 attttcgaac agtcgatgaa gacttttttg aagaattaga agaaacactt atcggtgcag
    39001 atgtaggttt tgaaacagcg atacgaatta ccgaagcatt acgtcaagaa gtgaaactca
    39061 gaaatgcgaa aaaatcggca gaagtccaaa atgcgatcat cgagaaactt gtggatctct
    39121 atgaagcgga aggaatcaat gaagtaaatg aactaaatat ccaagaagac ggactaacag
    39181 ttattttgtt tgtcggtgtt aatggtgtag ggaaaacaac aagtattggt aaacttgccc
    39241 atcagttcaa aaacgaaggt aaaaaagtat tgatggcagc agcagatacc ttccgcgctg
    39301 gagcaatcga ccagttagtt gtctggggcg aacgcgctgg tgttgaagtt gttcgtggca
    39361 atgcaggagg cgatccagca gctgtcgtat tcgatgcttt ggaaagagca aagacagagc
    39421 aggcagatgt tttactagtt gatactgcag gccgactgca aaataaagtg aacttgatga
    39481 acgaattaga aaaaataaaa cgagtaatcc agcgggaatt accagaagca ccccaagaaa
    39541 cacttcttgt attagatgca accactggtc aaaacgcgat ggttcaagca aaacaattca
    39601 aagaaacaac agatgtgacc ggtcttgttt tgacaaaatt agatggtaca gcaaagggcg
    39661 gtatcgtact tgctatccgt aatgaattgc atttaccagt gaaattggtc ggtcttggtg
    39721 aaggaatcga tgacttggag ccgtttgatc caaatgattt tgtcgttgga ttgttcaaag
    39781 gattactaaa agaagaataa cccatgtcta aaaagcagga gctgtgacaa aagttgcagc
    39841 tccttgtttg aatgattgtt tttaacatag ctgtgttttt gatgccttca tttttatact
    39901 tatttgtaag cggttctcaa acaatttcgt tctttttctt agactttttg attataatta
    39961 gattcatatg aattggaggt cacttaatga tgaattttaa gcaattatta ttgcatgtca
    40021 atgcgcgccc ttttatcgac caagctcgat ttggtataga acgggaagga cagcgggttg
    40081 atcttgcagg aaatctagca aaaaccgatc atccagcaat ctttggcgat cgatcctatc
    40141 acccctatat ccaaacagat tttagcgaaa cacaaacaga gatgatcacc cctgttaccg
    40201 attctattcc cgaattattt cagtatctcg ctgctgttta tgatgtgact gctcgttcta
    40261 taccgaaaga agagatgatc tggccattaa gtatgccacc tgccttaccg gaaaaagacg
    40321 aagagatcat tattgcaaaa ttaaaaaatt tcgaagatgt cttgtatcga cgttatttag
    40381 caaaagaata cgggaagcga aaacagatgg taagcggtat tcatttcaat tttgaatttg
    40441 gcgatgagtt gctaagaaca ttgttcagcc atcaggaaga atttcaagat ttttccgaat
    40501 tcaaaacaga actttatttg aaaacagcga gaaactttat gcgctatcgc tggatgatca
    40561 cttatttatt cggtgcttca ccaatgagtg agaagaacta ctttttagat gaatcacatc
    40621 cgcaagaacc tgttcgcagt attcgcaaca gtgcgctggg ctatacgaat catccaaatg
    40681 tgaaagtttc ctatgcttct atgaaacagt atttagcaga tatcgagcga atgatcgaag
    40741 aagggaaact ttcggaggag aaagaatttt atacaccgct tcgtttccga ggcggaaaga
    40801 aagtcgcaga tttagcaaca acaggtgttc gttatattga attgcggaat atcgatttga
    40861 atccttatgc aagattgggt atcaatccag agcaagttcg gttcttacaa ttattcctga
    40921 tgtacatgtt atggacagaa gaaaaagaag actgtgacca atgggtagca gaaggtacga
    40981 ctcgaaataa caaagtagca ctagaacaac catcagatca aacagaattt catcaagaag
    41041 gtagagaaat tcttgaagga atgaagcaaa tgctggttga attggattgg ttggattctc
    41101 tttatttagt agaggaagca ttgactcaaa tggatcatcc tgaacaaacg ttagcagcga
    41161 aactctatca agaagcacag ctatcgagtc agcaagaagt tgctgtggca ttgggacatc
    41221 aatattataa agaaagccat gaacgtccct atcagttggc cggttttcgc gaaatggaac
    41281 tttctactca gatatttatg ttcgatgcca tccaaaaagg tgtccaagtc aaagtattag
    41341 atgagtcgga tcaatttttg cgtctgcaat tccaagacca tgtagaatat gtgaaaaatg
    41401 caaacatgac aagtaaggac agctatatcg tcccacttat catggaaaac aaaacagtaa
    41461 cgaaaaaagt cttaaaagaa gctgggttcc gggtaccagg aggcgcagaa ttttcatcca
    41521 tggaagaagc ggtaaaagct tatccgagat ttgccgagca ggcatttgtg atcaaaccta
    41581 aatcaaccaa ttacgggtta ggtatcacga ttttcaagga aggagctagt ctggaagatt
    41641 atcaagcagg tttagccatt gcttttcgtg aagacagttc ggttttagta gaagaattta
    41701 tgccgggaac ggaatatcgt ttctttgtga tcgacggaga agtccaagcc atcatgttgc
    41761 gagtccctgc taatgttatt ggtgacagta tccgaacagt gaaagaactt gttgaagaaa
    41821 aaaatagtga ccctttgcgt ggaacgaatc atcgtgcacc tttagaattg atccaattag
    41881 gtgaattaga acaattgatg ttgaaagaac aagggttgac gatcgaatca gttccccaag
    41941 ccaatcaaat tgtttatcta agggagaact caaatatcag tacaggtggt gattcgatcg
    42001 atatgactga tgaattttct gaagcttaca aaaaaatcgc cgtttctgcg gtagaagcac
    42061 taggagctaa gattagtggt atcgatttga ttataccaga taaagaaatc gatcctacaa
    42121 ctgataaaaa agcatatggg atcatcgaag caaatttcaa tccagccatg catatgcatg
    42181 tttatccttt tgcaggaaaa ggcagaagat tgacgatgaa tgtattgaaa ttgttatatc
    42241 ctgaagtatt ttaaaagaaa aagcttttga cagattgtcc tatttgatgt caatctgatc
    42301 aaaagctttt tttgcatgta aaaatttatg tgttttttcg ttttaaaata aacgatccca
    42361 gaagcttttt ttcttttttg gtttttcttt ttcagctggc gaagagtttt cttctgggta
    42421 ttttttttcg atatcaatca caggttcatt tactgcttct tttgctgtta agagcaatcc
    42481 gaattcctca ggatttgcag tgacgtaatc gttgactaca gtgaaacggc tattgttttt
    42541 cgttgctagc tggatatatt ggttttggac agaaaggggt agagccccat tcaagagtat
    42601 ggaagcatct ggatgttttt tgagttcttt taaaaagttt tctttgtttt ttggttggat
    42661 catttcagca acagtcatac taagatagca gcgttccctg aatgtcccta aatatttatg
    42721 ctgttcttca gggttcacta aaggtgtacc ataaagtccc ttatccaaat ggctttttac
    42781 atcatcttgt gccataaaaa ataccctcct tcttctcttt gtctttctta cgattatagc
    42841 atattcccaa taatacctaa aacatatgaa aaagcggttg cttttgttca acgattcact
    42901 taaaataaga atgaaaatca ttctcaatta gaaaggtgga ttggatgcgc tacggacgac
    42961 tagtagcatt attagttatt ttaagtagta tttcattgtt catcggagta tcgaatgtac
    43021 aattgtcaga actgctccag ttagatgggc aaagcttaca aatcttgcta gtgactcgtt
    43081 tgccacgaac gatttgtttg atccttgtgg gagcgaccag tagtatttgt gggttgatca
    43141 tgcaacattt gacccaaaat aaatttgttt caccaacgac tgcgggcacg atggatagtg
    43201 cgcgtttagg tattttagtg gctatgattt tcctacctgg tgcatccttg attgtccgat
    43261 ccttgacagc attttgcttt gcttttgcag gaacattgct ttttttatcc cttacgcgat
    43321 tgttcctcca gaaaaatcaa ttgatgcttc cgttgattgg agtcatgtta gggaatatca
    43381 ttggttcagt tgctactttt tttgcttatc aattccagtt ggtacaaaat atgacttcat
    43441 ggcttcaagg gaattttgcg actgtgatac gaggaaatta tgagttattg tatgctgttg
    43501 ttccattgtt gctcttggtt tggctatttg cttaccgatt tacgatcatt ggtctgggcg
    43561 aatcgtttgc agtaaatctg ggaatagatt accagaagat gcagttttta ggcattggct
    43621 tagtatcatt ggctagtgca gtcatgttga tcatggtagg aagcattcct tttatcggag
    43681 tgatcattcc gaatcttgtc tctagaatat atggagatca agtgcacaaa acaattggcg
    43741 taactgcttt agcaggtagt ttgttcttag tattttgcga tcttgtcgct cgcgtgttga
    43801 tttttcctta tgaaatacca gtcagtgtga tcgttggaat catcggtggg gctatcttcc
    43861 tttatcttct gataagggga cgacgatatg cttaaaaaaa agccatctat ttttattggt
    43921 atgcttgttc ttgttttatt tgttacagga atgtacttga cgatccatac atatggaaac
    43981 tggcattttg catgtgcatt gaggagtaag aaaatttttg catttatcct tgtctcgcta
    44041 gctgtcagca gtgccacaat cagctttcag acaattacgc ataaccagtt tttgactcct
    44101 tcagtattgg gacttgagtc gttatatgtc cttgtccaaa cggtcctttt cttctttatc
    44161 ggaggagtga cgatgcttca gcagacaggt acagtttttt tcttattgaa cgttgggctg
    44221 atggtcgggc tgagtctatt gttatttttc tttcttttga aaaaaatgag agcgaatctt
    44281 tttttattac tgatgtcagg gatgatttta ggtacgcttt ttggtagtgt cagtaccttt
    44341 ttacaagtca tcatggatcc gaatgaatat gatttgcttc aaggcagatt atttgcaagc
    44401 tttggcaata tccagagtca gtatcttttg cctgcttctt tgatcattat cggctgctgg
    44461 tacctgttat ttcgatatcg acatgtgcta gacgttttcc atctcggaaa tgaacaagca
    44521 gtaaacctcg ggatagacac agatcgtttt gaatttttga ttttatgttg tgtcagtctt
    44581 ttgacaggga catcaacggc tcttgtgggt ccagttactt ttttagggtt tattgtcgca
    44641 aatatcagtt atcgtgtctt ttctacttat cgtcatggtc agctatttat cggaagcttt
    44701 ctggtagcta tgctgtttct gacaggagga cagctcgcag tagagcagat tttcggctgg
    44761 aatacaacag tgagtgtcgt cgttgaattt gtcggaggaa tttattttgt cacaaaattg
    44821 attcgcgaaa ggaagagtat cctatgattg atttacaaaa ggtcaataaa ctgtaccatg
    44881 gaaaatcagt ggttaaagat gtacagttaa cgattcctga aaagaaattg actgctttta
    44941 tcggtccaaa tggtgctgga aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa
    45001 aagatacagg tgaaatctat ttagaccata acgaagtaaa ggcttggaaa tccaatgaat
    45061 tagccaaaaa attatcgatc ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga
    45121 aagaattagt agaatttgga cgatttcctt atacgaaagg aaaattgacg acaaaagacg
    45181 aggaaatcgt tcaggaatca ctggaacacc ttgggttaga agaaatagcg gatcaatcga
    45241 ttgacactct ttcaggcggt caactccaac gtgcgtatat tgcaatggtg ctagcgcaag
    45301 acacggatta tattttactg gatgaacctt tgaacaatct agatatgaat tttgcggttc
    45361 aaatcatgca gattttaaaa aatttagtac aagaaatcgg gaaaacaatt gttattgttc
    45421 ttcatgatat caactttgct gcaagttatg cagacgaaat tgttgcaatg aaagatggac
    45481 agttatttac gcaaggaacg acccaagaaa tgataaaaaa agatgtattg gatgaattat
    45541 acgaaatgga catacggatt tgtgagattg aaggccgcag attctgtctt tatttctaaa
    45601 actaacatta ggagagaaga gatgaaaaaa ttagtagtag gtatcttgat tctagcatca
    45661 tttggtttag cagcatgtgg aaatagcaac aacaccagtc aggcagacac aaaaaaaagc
    45721 agcacacaaa ctgaaactac attgacgata acagatagta atggagacca aatcgaggtg
    45781 ccaaataatc cagaaaaagt cgtcgtattc gacaatggtt ctttagatac gatggatgct
    45841 cttggtgttg gagataaggt agttggagca gctacaagca gccttcctga gtatctttca
    45901 tcctataaaa aagtagaatc agcaggtgga ataaaagaac cagacttaga aaaaattaat
    45961 cagcttcagc cagatctaat catcatttct ggccgacaaa gagattttca aaaagatcta
    46021 agtcaaattg ctccgaccat tttcctttct ttagatgcga aaaatccatg ggaatctttc
    46081 cagcaaaatg tcactgcttt aggggagatc tttggtaagc aagaagaagc taaaactcaa
    46141 ttagaggaat tatctagtgc aatcgatcag acgaaaaaga aagcagaagc tactgacaaa
    46201 aaagcactag tcacacttgt gaatgaaggg caattatcag cctacggatc tggttctaga
    46261 ttcggtttca tccatgattt atttggcttt gaacaagcag atgatcaaat cgaagcatcc
    46321 actcacggtc aaagtgtttc ttatgaatat gtgctggaaa aaaatccgga tatcttattt
    46381 gtagtagaca gaacaaaagc tattggtgga gacgacagca aagatgatat ttctgccaat
    46441 gaactggtag cacaaacgaa tgctggtaaa aatcagcaga tcatctccct tgaaccagat
    46501 gtctggtatt taagcggggg cggtttagaa tcaatgaaac tgatgatcga agatgtgaat
    46561 caagcattta aatagcataa ataacagagg attaaactct catactatgt aacaataatg
    46621 tttcttacat tcttaaatag caagagccta tcctcaaaga agttatcaaa aaccatccgt
    46681 aaaatcgtat tgatgatttt acggatggtt tttatttatt tgagaaatct tttttcaacg
    46741 tgaattcatt atctacatca tacgggttga ttctagaatg gggagtggca aaaaatagtg
    46801 tgatccattt tttcagcatc aagatcgcct cctttgattt gaatcaaagg tacaaagcga
    46861 aacttagata aaacttaaat ttagatattt ttattttgta ccgatctctt ctttaaacga
    46921 tgttccatct gctgcttctc ggcaataagt ccactagact agaaaatatg agaagctatt
    46981 ttctgtccag cgttcttatt actcaaagca aatcgcagtt gtcacaatct cttctaaacg
    47041 atgttccatc tgctgcttct cggcaataag cccactagac tagaaaatat gagaagctat
    47101 tttctgtcca gcgttcttat tactcaaagc aaatcgcagt tgtcacaatc tcttctaaac
    47161 aatgttcaat cagctgacct tcggtattag ctcaaagcac tgatttcaca acctctattt
    47221 aggcatgtgt ctcagcaagc ggttgatagt tgatgatctg catttttcga taaaaatcgg
    47281 cgggaagctt actccaccgt tttaataatt gatagaaata actctcttct gctttgattt
    47341 tatactcgct taatatcaat ccaaaactat tcgttttttt tgaagctaat tttttataaa
    47401 tatccaatgc tttggtttta tcttcattga caaagagtgt ttttacttca atataagaac
    47461 cctcgatatt ttgtgtttct tcgataaaat agatgttttt tatatattcc ttcatagtga
    47521 ttcctccaaa gaagtctttt atttgataag tttactctac cgaagagttg ttaataatcc
    47581 gtgaacaaaa agtaattctt tttccaatag ttgttaaagg ttttttattt tttatagtat
    47641 tttttgttat ttaagaaagg aataaggtta aacaaataac aggttgcttt ttgggtcttt
    47701 ttccgttcaa gaaactgaac gaagaaaagg gaaagttgtc tcttttgtga taagagaaat
    47761 cataataaac gaatgactta ctttccaata aattgagaac agtcagaacc agacaaatta
    47821 gttgcatctg atgaataaag tgattattct atgacatgag gtgatacaga tgaaattaga
    47881 agtgacaaaa gaagcacaag aagtattgaa gaataaatta gaagcagacg atcaactttt
    47941 attagatatc gaaaacggtg acggtccatt tgcagaaagc caagtcagtt gccaattgga
    48001 tacggcattt cgattgatca ttgtcaaaaa agatacacaa acagatctaa gtctttattc
    48061 tgtagtggct gatacaccag ttggaccaat caaaatcaaa gacagtgcaa tactttacat
    48121 ggatgatcca tccacacttg ctttagaacc aacttataat agtttacaat taaaaggacc
    48181 aagcggcttg agaaaaggca acttgcaagt tgttcgaaaa gactagaggg ataaaatggg
    48241 aaaattggcg atcatcagcg acctacatgt ggacatcaat aaattcggcg aatcagagct
    48301 gatgcagctt tggcaagttt tgcaaaagca caagatcact cggcttcatc tagccggaga
    48361 tacggctaat aaagtagacc gttgcctagc tgttgtcgaa tttttcgtca ataaaggatt
    48421 atctacgaca tttcatttcg gcaatcacga gttggcagat gtgcccaatg aacagatgat
    48481 ggaccatttt ccagacccac attttttaaa tgaacggtat attgctttaa atgagcagac
    48541 cgttctttta gggatgaatg gctggtacga ctatcagttt tccgaattga aagattacga
    48601 ggcaatcgta cgaatgaagc gtttgtattg gtatgatcgg ttcatccagc gtgggaaaac
    48661 agatctcgag gtcaatgcag aaatgcttgc agctgcaaaa aatttgctag accagctgga
    48721 agcaaaaaaa cttgaggtga ttttatccac tcatttcgtt cctaaacggg catttatcat
    48781 gtatcaatct gctccttatg agcgttggaa caaattaaat gcatttttag gatcagaatc
    48841 attcggagaa ttacttgacc gttattcaaa tatcaaacaa gtagtttttg gccatacgca
    48901 tcgtcgcttt gaagataaat ccatcggtca cacgatttac agctgcagac cttttggtta
    48961 ttattatgaa tggcagctga cccgagattt tgtcttgaaa gaacagttgc tagacagcta
    49021 tgatcctatg aaattacgtg tcctcttgcg tgcccatcac ccagcttttc aggcctatca
    49081 aacacaacat ttgcaagagg aatttgaaca agcgatgaca atcgttccgt attgagacag
    49141 cattagtaat gtgtaaaaga aaataccttg taaaacataa ggataagtaa gagcagtaga
    49201 tccatttatc gtggatatgc tgcttttttt gcggaaaata atcagcgaat gtttatttga
    49261 tcggatgatt tgtaactcgc agagtactag atgcaagcgt gtattctttt tttgaacgat
    49321 aatcacaaaa aaaaatataa tatacatttt ttatttaatt ataattaata ttgattgaag
    49381 tctaggcagt caagtcacat tttgatagat aggaggggga cttacgaatt attttaaagg
    49441 ctatgacagc tgtatttcta gattgtgttt gcatcaagtt gcaataaaaa ctagaaatca
    49501 aatcgggctg ataatcattt ataactaatc gatacatagg accaaatata ggtctatgtt
    49561 cttttatttc ataagtatcg taaaacagaa ttttgctatg gattaatcca atcgactgat
    49621 atgtttagta aataaagaaa gaggaatgtc aatgatgaaa aaagaaatcg tattaacagc
    49681 agcaatgatg ttattcagca tggtagcaag tacgactttt gtttctgcaa ctgaagtata
    49741 cccaaaggaa tataacacag aaggaacgat tacatttgaa gcaggagatg agggtgtaac
    49801 tcctcctgtt gatccagaga atcctgatcc caataaacct gtcgatccat cagatcctcc
    49861 aagccctgga acaggagggg cattatcgat tgattatgga tcaaaattca aatttgggac
    49921 tcaaaaaatt tctactgcgg ataaaacgta ttatgcagct gctgatgtga tgaacgatgg
    49981 gtctagaaaa ccgacatatg tccaagtgac agataggaga agtaccttat ctgggtggaa
    50041 attaagtgtc tctcaaccag aacagtttaa aactgccagt ggggatgaac tagttggagc
    50101 acagctgaaa tttacgaaag ggcaggctgt ttctttggtt gatccaacat atacgccgca
    50161 aacggtgaat tctgaattaa cgttgacacc gggaggaaac aatacgttag caattaatgc
    50221 taaatcagga acaggtgtgg ggacttgggt ctatcgattt ggtgcaaatg aaaatgaaaa
    50281 tcaagatgcg gtacagcttt cggtacccgg taaatctgtc aagttagcgc aacaatattc
    50341 cactaaatta gtttggacat tagaagatac acctaacaac tagtttactg aaaagaactg
    50401 ttaaaaataa atacgtagtc atattgtctt gcgaggtaat cgagcaaaaa ttgtcaaagg
    50461 ctaggctaaa tttgtttgga tacgaatagt tcatctagga atttaacgat caggaggaaa
    50521 agatatattg aaaaagagga ggatcgtgct cattttaagc agtctcttag tgactaatat
    50581 ctttccgatc atagggtact ctttggaatt gaatcagttg gagcatggaa atagaagaga
    50641 cgaagaaagc aaactcactt cgacattcga cagtttaata gaatccaacc agacacaaga
    50701 aagcagtgag gatttaagta tttcgagtag tggagagacc actgacaacg tagaagctga
    50761 gggttcggac aaacaaggac tagaagatgc accaatttct gcggttgagc tgcctgacga
    50821 tcccaatatt atttctatcg ataaaatttt tcaaacacct atcggtacta gcacgtccat
    50881 attggaaaat gggaagttac tgcagttgaa cccagcagaa aggtctcaaa gaggagctat
    50941 ttggtcaaat aagaagatta gtttactctc ggattttaca tttaaatctt atttatactt
    51001 aggaaatcaa cgagatagag cgggagatgg catgaccttt acattgactg gcgatcctag
    51061 aatggctagt aatcccagtc aagttattgg atcgccaggt atgggaattg gctcatattc
    51121 tactcgttct ggccaacctt acattgcgaa tgcgctctcg attgagtttg atacgtataa
    51181 aaatagtggt tcttctgatc gaatggatcg agagataact gctgataata gagggcatgg
    51241 acatgtcgct tttgtcacgc ctaaaccaaa taataataat tattctggag agcatactgg
    51301 cgtgacggta gctcctacat ttctttctaa tggcacatgg cgcttgttaa taattaaatg
    51361 ggacgcggag caaagaagtc ttacttatga tttggaaggt gtcggtcact cttctcggat
    51421 tatacctgat ctcattaggc agtttggttc tacagaagta aattgggggt ttacttcttc
    51481 aacaggtact ttttttcaag aaaatgctgt cgctgtcacg cgacttccat cgaatgtcac
    51541 atcaacagct gatgtaaaag tcaacgatag tgattatggg gccatcgctg aagctggagg
    51601 aaacgataag ataactatca gaaatacatt gaaggtcgag ggggattttc ttgaatataa
    51661 gaaaatgcag actagtatcg acctcccaca agaattaact attcccgagc atatcttgat
    51721 caatggaaat caaattgatg ccaaagatat cttgataacc ggaaatcgag tcacgctaaa
    51781 tctgacagat tattttattg ctggagatac gttaataatc gaattggaga caactttgca
    51841 ggaagtaatt cctgaaaaag tactcactat gcattttgaa taccttgaaa acgggaattt
    51901 gattgagcaa tcgaatgaaa taaacctaaa gatcgcaaag ctgaaggaga tagatatcca
    51961 tgtttattat aaagataaag acagtcagat tgatattgct gaaatgaaaa caatcactgg
    52021 gaaaatagga gagaagtata aagaaactcc tattgatatt gaagggtatg tttttgactc
    52081 ggattcagcg aatacagaag gcatcttctc cgaaaataca gaggatatct atttttatta
    52141 cagaaaaggc aaactttatc tctcaactgc tcctcaatat gtcaattttg gaaaacataa
    52201 aatatccagt agaccattaa gtgaattcgg acagttttca ggtgggttga aaattataga
    52261 tgaacgggct tttggaagtt ggaaattaca attgaaacaa gagaaagttc ttacaaatgg
    52321 agattttgag cttccagaag ctctttcctt tgttacctct gaaaatacaa cggttatagg
    52381 gacatccgct gttacgattt tcgaaagtga tcaaaagggt gaaagcgatt tgtcctctct
    52441 tttagattct acagctcatc gtggaatcag aatagatatt cctgtagaaa accaaagaat
    52501 cggaaccttt gaggggaaac tatcttggat acttgcagat gtcccaggaa attaacagga
    52561 agagaagaat ataacaaaat tattgagttt caagaagggc acaggtacca taggctcttg
    52621 tgtcccacag agacaagatt ttgttatagt cttctcttac atatgattaa aggagcgatt
    52681 ttcttgagac caaaacaaca attatttata acactcctag ttattttagg ggcacttttt
    52741 aacaatatat cagtgtcagc tagtgcattt aatttttcag tgacgccgat aacttcagag
    52801 aatcaaatcg acaagagaaa aacttacttc gatcttcaac ttgatccgga tcaggaagta
    52861 gaagtaaaag cggaattgag aaatgataca gaaaaagaag tgaaaatcga tatttctgtg
    52921 aatagcgcaa ccaccaattc aaatgtgatg gttgaatacg gaaaaaacga gattgaaaaa
    52981 gacatgagcc tgatctttga tctggtagat tatgtgagct atccacagat agtgacgcta
    53041 aaacctaaaa gtgtccaaac cgttgctttt catgtcagga tgccgaatga gcgatttgat
    53101 ggtgtattgg ctggtgggat cacattccaa gaaatccaga cggaaaagga ccaaacagaa
    53161 actaaggatc aaagcttatc gattgagaat gaatacacct atattattgc tttgttgatg
    53221 caacagacac tgaacgaagt tgctccgaac cttactcttc atgaagttaa accagatcaa
    53281 atcaatgcaa gaaatgtcat cttagcaaac gttcaaaatg atcaaaaaac ctatatcaat
    53341 caagtagtta ttgaaacaaa aattacaaaa aaaggacatt ctgaagtttt atatcaagag
    53401 gaaaaagaag gattgcagat tgcgccgaat acaaattttt cttttccaac tgctttaaat
    53461 ggtcaaccgc taaccccagg tgaatatcac cttacaatga ctgttttagg aaatgaaaat
    53521 gaaaatggaa aattttcgag aaaaaaagga aatactacga tcaactatac caatcaatgg
    53581 gtatttgaaa aagattttac aatagacgga aaagtagcca aggaattgaa cacgacggat
    53641 gttacgatta aaaaagacaa taattggatt tatatcttag tagcttcact tttcttattg
    53701 tttattttat tatgcatact tttgtttgtt ttgagaaaaa aagaagagaa agaaaagtaa
    53761 ggttaagata acaaatagta aatttttatt attgtaggat ggttgggctc tttttataac
    53821 aatataaaat ataccatttt attaataaaa atgcatacta gtaaatgata taattctaat
    53881 aacaggtttg atcgcgagaa aggccaaata aaacgctctc caaaatgtta aaaaaaagac
    53941 aggacgatgt atattataca aacaagaatc gctgacaaca gtgactcgga tccaggaaat
    54001 cagttttatc cccagctagt tggtgaatgc atggaaagta atatacgtag aaagagctga
    54061 tgactaatga attatgagtt ttttttaagc aaagaagatc acagaagtta ttcattactt
    54121 aaatatttag aagcaagctc aaatttatca gagtcaatat cgaatgttca agaagagttg
    54181 tcgctatcga catttctctt gaaaaaaacg atcgataagc tgaaacatga tttacaaaag
    54241 ttcgatctag agaaaaattt gcgagtaacc gtcagtgaat tggatatatg tctggaaatt
    54301 aatggaaaat gttctagcaa agctctgtta tctcgttata taacggattc tttatctatg
    54361 aaaatggtat tggctttctt tcaggaaaaa tatatctcag tagaaaattt tgctaaacag
    54421 catcacgtga gttattctgt ggcttataaa gtattacaaa gactaaaaag aaatctaaaa
    54481 aaatatcaaa ttttttttga aaagagaaag ttg
//
LOCUS       DAIGTA010000016        48534 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.016, whole genome shotgun sequence.
ACCESSION   DAIGTA010000016 DAIGTA010000000
VERSION     DAIGTA010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.016"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(297..764)
                     /locus_tag="NOB43_000964"
     CDS             complement(297..764)
                     /locus_tag="NOB43_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCI0981845.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(884..2422)
                     /locus_tag="NOB43_000965"
     CDS             complement(884..2422)
                     /locus_tag="NOB43_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCI0981846.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            2502..3188
                     /locus_tag="NOB43_000966"
     CDS             2502..3188
                     /locus_tag="NOB43_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCI0981847.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(3389..3916)
                     /gene="msrA"
                     /locus_tag="NOB43_000967"
     CDS             complement(3389..3916)
                     /gene="msrA"
                     /locus_tag="NOB43_000967"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0981848.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(4000..4677)
                     /gene="pgmB"
                     /locus_tag="NOB43_000968"
     CDS             complement(4000..4677)
                     /gene="pgmB"
                     /locus_tag="NOB43_000968"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI0981849.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(4674..5804)
                     /locus_tag="NOB43_000969"
     CDS             complement(4674..5804)
                     /locus_tag="NOB43_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0981850.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(5804..7987)
                     /locus_tag="NOB43_000970"
     CDS             complement(5804..7987)
                     /locus_tag="NOB43_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI0981851.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(7984..9009)
                     /locus_tag="NOB43_000971"
     CDS             complement(7984..9009)
                     /locus_tag="NOB43_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0981852.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(9054..9881)
                     /locus_tag="NOB43_000972"
     CDS             complement(9054..9881)
                     /locus_tag="NOB43_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI0981853.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(9878..10945)
                     /locus_tag="NOB43_000973"
     CDS             complement(9878..10945)
                     /locus_tag="NOB43_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HCI0981854.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(10971..11807)
                     /locus_tag="NOB43_000974"
     CDS             complement(10971..11807)
                     /locus_tag="NOB43_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0981855.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(11804..12673)
                     /locus_tag="NOB43_000975"
     CDS             complement(11804..12673)
                     /locus_tag="NOB43_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0981856.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(12743..14026)
                     /locus_tag="NOB43_000976"
     CDS             complement(12743..14026)
                     /locus_tag="NOB43_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI0981857.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(14040..15725)
                     /locus_tag="NOB43_000977"
     CDS             complement(14040..15725)
                     /locus_tag="NOB43_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HCI0981858.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            16000..17025
                     /locus_tag="NOB43_000978"
     CDS             16000..17025
                     /locus_tag="NOB43_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0981859.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(17620..21294)
                     /gene="rpoC"
                     /locus_tag="NOB43_000979"
     CDS             complement(17620..21294)
                     /gene="rpoC"
                     /locus_tag="NOB43_000979"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCI0981860.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(21352..24969)
                     /gene="rpoB"
                     /locus_tag="NOB43_000980"
     CDS             complement(21352..24969)
                     /gene="rpoB"
                     /locus_tag="NOB43_000980"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI0981861.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            25697..26665
                     /locus_tag="NOB43_000981"
     CDS             25697..26665
                     /locus_tag="NOB43_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0981862.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            26683..27588
                     /locus_tag="NOB43_000982"
     CDS             26683..27588
                     /locus_tag="NOB43_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981863.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            27585..28391
                     /locus_tag="NOB43_000983"
     CDS             27585..28391
                     /locus_tag="NOB43_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0981864.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            28527..29516
                     /locus_tag="NOB43_000984"
     CDS             28527..29516
                     /locus_tag="NOB43_000984"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HCI0981865.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(29833..30357)
                     /locus_tag="NOB43_000985"
     CDS             complement(29833..30357)
                     /locus_tag="NOB43_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HCI0981866.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            30644..32444
                     /gene="scm"
                     /locus_tag="NOB43_000986"
                     /pseudo
     CDS             30644..32444
                     /gene="scm"
                     /locus_tag="NOB43_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
     gene            complement(32599..33585)
                     /locus_tag="NOB43_000987"
     CDS             complement(32599..33585)
                     /locus_tag="NOB43_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI0981867.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(33608..34174)
                     /locus_tag="NOB43_000988"
     CDS             complement(33608..34174)
                     /locus_tag="NOB43_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HCI0981868.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(34188..34604)
                     /locus_tag="NOB43_000989"
     CDS             complement(34188..34604)
                     /locus_tag="NOB43_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCI0981869.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(35061..36995)
                     /locus_tag="NOB43_000990"
     CDS             complement(35061..36995)
                     /locus_tag="NOB43_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0981870.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            37276..38232
                     /locus_tag="NOB43_000991"
     CDS             37276..38232
                     /locus_tag="NOB43_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HCI0981871.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            38322..39425
                     /locus_tag="NOB43_000992"
     CDS             38322..39425
                     /locus_tag="NOB43_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCI0981872.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            39438..40391
                     /gene="menA"
                     /locus_tag="NOB43_000993"
     CDS             39438..40391
                     /gene="menA"
                     /locus_tag="NOB43_000993"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCI0981873.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(41326..42672)
                     /gene="gor"
                     /locus_tag="NOB43_000994"
     CDS             complement(41326..42672)
                     /gene="gor"
                     /locus_tag="NOB43_000994"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCI0981874.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(42806..44059)
                     /locus_tag="NOB43_000995"
     CDS             complement(42806..44059)
                     /locus_tag="NOB43_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI0981875.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(44065..44988)
                     /locus_tag="NOB43_000996"
     CDS             complement(44065..44988)
                     /locus_tag="NOB43_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI0981876.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(45209..47701)
                     /locus_tag="NOB43_000997"
     CDS             complement(45209..47701)
                     /locus_tag="NOB43_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCI0981877.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(47708..48175)
                     /locus_tag="NOB43_000998"
     CDS             complement(47708..48175)
                     /locus_tag="NOB43_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HCI0981878.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(48311..48384)
                     /locus_tag="NOB43_000999"
     tRNA            complement(48311..48384)
                     /locus_tag="NOB43_000999"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48348..48350),aa:Arg,seq:acg)
     gene            complement(48442..48515)
                     /locus_tag="NOB43_001000"
     tRNA            complement(48442..48515)
                     /locus_tag="NOB43_001000"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48479..48481),aa:Pro,seq:tgg)
BASE COUNT        13882 a        10387 c         8963 g        15302 t
ORIGIN      
        1 aaaagtcttg tcacaacccc ttattttgaa taaacggtgt tctcctgcca actcctcggt
       61 cacaagtcac aatatccata aaacataaga agctgttttt taaaattgtt tcttgtgact
      121 cggagctgaa cggcaggctt acaacctctt ggtaaacggt gttcaatcag ctgaccctcg
      181 gtattagctc aaaaaacggc aaaatatgag gaactatttt gacgtttgtt tctctaatac
      241 tcaggtcaaa acgctgattt cacaacctct ttttcggtca agttcaacaa cagtttttac
      301 gcgtcgatct ctggcgcttt gcccaaatga gcttggatca tccagatacg tttttctgtg
      361 gctgttttga attcgataaa gatatcttgt gttggatcgt cgccttcttc tccagaaact
      421 tcgattcctt tttggtaaag atctgctaga taacgatagc ctgcaacaag tgtttccaaa
      481 cgttctggaa tagtacgatc ccagcggcca atttcatcag ggatttttgt gttatctgca
      541 aattcacgca atgtagaata aggtgaaccg tctaatgtga tcaagcgttc ggatacttca
      601 tctaactgag cgttcaaatc atccatgaac tcatccatca ttgggtgcaa tgtaaggaaa
      661 cctggtcctc tcatgtacca atgtgtttgg tgaacaacaa cagacatttg gcttagatct
      721 gcaactaatt gatttaatac ttctttggtt tgttggaatt tcatctttct tgcctcctaa
      781 cattttctta cacttaaaat aatagtagac tttcaatgaa aagtacaaca aaatcattta
      841 cctgagaacg attttcagtt cgctttttta tccgtaaagc caatcatttt tcagaatcag
      901 ctaattcttc tcgcagttga gcaaattgct gataagtctg tgctaaatgc ttttgtgtcg
      961 aaacaaataa tggatagatt ttctgatatt ttttatgatc agtttcttgt actccaactt
     1021 gctctttcaa ttctatcaat tcctgtgctt cactgatact ttggatcttt ccgatgcttc
     1081 tccagcctaa aatcacagct cctaatgcgg atgcttctgt gacagtaggg aaaacaagcg
     1141 ggtaacccag tacatcagcc atcatctgac gaaaaatcgg agattgagca aacccgcctg
     1201 tagcacggat ctctgtgagc tgattttcct ggcaaactcc ttttaaaatc cgataaaggt
     1261 tgagacagat cccttctaga atcgccttca tcatttcttt ttctgtatgt tgccgctgta
     1321 aaccgataaa actgccaaac gcatctgcgt cccaaagcgg tgctcgctca ccaagtaaat
     1381 agggatgaaa aatcagacca ttggcacccg ctggcacaaa agcgatagcc gaaagcagtg
     1441 catcatatgg attttctcct ttttctttag cagattgaac gacttcctgt aaaaatgtat
     1501 gccctgccca atcaaagatg ccagcaccat tgctagtcgc tcctcccact acccaatgtt
     1561 tctgatccag aacataacaa aacgtctcca tttctggatg gaactgaggc tgagtagtaa
     1621 taaaacgaag tgctccgctc gttcctacgg tcaaagcggc gatcgtatca ccaaaagcac
     1681 ctaaccctag attagaaagc ggcccgtctg cccctcccaa aacaaatgat atatcatttg
     1741 gcaaacctag ttctgctgct gtttttgatg gtagacctgt tacttgatag gtggaaggaa
     1801 agacttgcgg caattgctct attcgaatgt tcaagtagtc aagcacttct tctgcccatt
     1861 ggaattcatg gatatcaaaa tatccagttc ctgaagctgt tccgtagtcg ctgatcagtt
     1921 cgccaaacaa tctataaaag atatagtctt tgataccgac aaaataagca gtttttttga
     1981 ataattcagg ttggctgttt tgcagccact tgattttgtt caatggtgtc attggatgaa
     2041 tcggcgtccc agtctgccga taaaattctt tgccaagcac ggtatatttc agtttttctg
     2101 cttcgtccgc tgctcggtta tctgcccaag tgatcattcg agataacggt gttttctctt
     2161 catccaacaa tatcaggcca tgcatcgcag aggagaagga gacaaattga atgattgtgt
     2221 ctgaaggcaa ctgtttaatt acttctttta taacggtgca gacaccttga aagatcaatt
     2281 cctgatcttg ttctgccatc ccttgtgttt cttggatcaa agggtagcga aaataagcgg
     2341 atgctgcttc ttgggcttca tctgtgaaag caactgcttt ggtttgtgtg gttccgatat
     2401 ctaatccgat tgaaacgttc attttttcac ctcaaatttt atgtatgtac aaaaatttag
     2461 tttaagcttg cgtatcttgg ttttgaaaag ggggagatgg cgtgttactt tattttatca
     2521 ttggttgctg tatcggatca tttttatgtt taaccgccca gcggattccg ttaggtcact
     2581 ctattattta tcctagatct cattgtgtca aatgctgtcg ttcgctttct tggtatgaat
     2641 tgattccgat tctctcgatc atcgtccaac gatttcgctg ccgctattgc aggtgtcggt
     2701 tgcccttcta ctatttgttg gcagaagcct tatgtggtgg tctttttgcc tggttcttta
     2761 ctttttcttc cgcaagaaat ttttcgacgt tcatatggat gctttcggct ttgctatttt
     2821 cgttgatgga tttattttac ttcatggtcc attctcacac gctattctgt tcttgggcaa
     2881 ttttatggat tttttggttg caggccggcg tcttccaatg gcaaagtgtg ctgttaacgt
     2941 ttatcgtagg cggtgtgtgc cttcgctatg gtcaatccta tctcggagct ggcgatactc
     3001 tgttgatgct ttcttggagt ggtggcttgt ctctagaaga gttgcttcag atcttgtttc
     3061 ttgctagtct gtttggaata tccgtttttt ctgtttactt tatctgtcat aaaaaaaagt
     3121 tggaaaagct gcctttcatt ccttttttga gcagtgcgtt gctgattgtc cttcatctta
     3181 ggtattgaaa aaaggttgtg acaaacgact tgtcacaacc tctgatatat agtgttctct
     3241 taccaaatcc ttgtgacttg gagctaggcg acaggttcac aacctctcca ctaaatggtg
     3301 ttcaatcagc tgaccctcag tattagctca aaatgctggt tttacaacct ctgatatacg
     3361 gtgttccata agtagctttt tcggcttctt atttcttgac gccccaatgt cgacgaagga
     3421 aacctgcacg tccagaacct tctcgataaa gattgtaatg gagcttgttt ttcttgtaat
     3481 aatcctgatg gtaatcttct gcaggataaa attcgcttct tggttcgatt tttgtcacga
     3541 ttggcttatc gaatcgcccg ctgtcttgca atgcttgttt tgaacgctct gcaatatttc
     3601 gttcttcttc atcattatag tagatcactg gacgataaga atcaccgcga tcagcgaact
     3661 gtcctaatgc gtcagtcgga tcggtttgct gccaatagat ttccaccaac tgatcataag
     3721 aaataacttc tggatcatat tcgatctcta ctgcttctgt atgccctgtt gtgcctgttg
     3781 ttacttgttc ataagttgga tttggtacat gcccgccagt ataaccggat gtcacagaaa
     3841 tgatccctgg ctgctcttca aatggtttga ccatacacca aaagcatccg cctgcgaaaa
     3901 ctgctttttt tgtcatataa aatccccctt ttttctcatc ataccttgat ttccaaaagg
     3961 aggataacgt tttgcttgtg acagaaaaaa cggaaactat tatatacgtg atacggcttc
     4021 tgataaatgc caaaacgaac gtacttgatc aaaaacggtt aaatcaggaa tcacatattc
     4081 agcagaagga agatttatgt tttcacctat tcccaataca tgcatgttac cagccaaagc
     4141 tgcttgacaa ccagcttctg aatcttcaat gaccaagcat gcatttggcg gtacattcaa
     4201 ttgctgtgct cctttgagaa aaacttctgg atcaggtttt gcttttgata cttgcgtgcc
     4261 gtcaataagg acatcaaaat aacttgtcaa attcgttttt tctaaaatga ggcgtgcatt
     4321 tttgcttgct gatcccaatc cgatcttgat gtttgttttt ttcaagtact caagaacagc
     4381 tattgcacca ggcaaaacgg atgtttcatc cattttttga atcgcttgaa gatatagatt
     4441 gtttttttgc tcagcaaagg ctgatttctc tttttctgag aatttctgtt ccatttttcc
     4501 aaatgacagc aatcgctcta gtgactcggt tctggatatt cctttcagtt gctcgttttc
     4561 tttctcagtg aatggaatgg acagctggtt agctaaaacc agccacgctt cgtaatgata
     4621 acgagctgtg tctacaagaa cgccatctaa atcgaatagt gctgctttga ttttcatcga
     4681 ttacctcctt gaaaatgaac gacttgaagt aaagatgcga tgtttttagc tgtgcgatga
     4741 agattatcag tggcttgctg taaagcttct tgtaaaggca cagctgcagg aaggatcgga
     4801 aaaacggccg aaatgccaac atctgctgct ttttcgcttc ctttaccaac acttccgcaa
     4861 atagctatca caggaacgcc ctctggtact cttctagcaa tcccaactgg cgcttttcct
     4921 tttagacttt gtccatctag acgtccttcg cctacgatta cgaggtctgc ttgctgtacc
     4981 cgtttatcga actccagtaa atccaatacg tagtcgatgc cagagactat tttccctgaa
     5041 gcaaatgcta acagtcctgc acccattcca ccaccagcac tactgcccga tgcctcgatt
     5101 acttgagggg caaatctcat ataaaaatca tgcatggctt ggtcagccac tgctaattca
     5161 ttttctttca agcctttttg tggtccgaaa acaaaagaag cgccttcttt tccgcataaa
     5221 agattagtaa catcagtaat gacagtgatt ttggctttaa tcagctcaat aggcacgttc
     5281 gttttatcaa ctgtagcaat tttacctaga ttttctccca gtgcttctac tttttgatta
     5341 tcttgatcgt aaaaagcata acctagacct tctgccatgc cgatgccgcc atcgttggta
     5401 ctacttccgc caacgccgat gatgatgtgt cgaacacctt gttgcaacaa ttgtcgtatc
     5461 agttctccta ctcctcgcgt ggataaccta agtggctgtt gttggtttag tgggacatct
     5521 ttcaatccga cgatttctgc catttcaaaa atcgcagttt gaccgtctga agcgtactgg
     5581 atttctttgt ttttgccaaa tgcattagta acgactgctg tttgccgctt caaccttaaa
     5641 ctgtctgcta atgatgaaac cgttccttct cctccatcgc ctataggtag cagatcatat
     5701 tcagcctgaa caaaaacttc ttgaaaacct gattgaatgg cttgtgctgc ctctaaggct
     5761 gtcagacttt ctttgaaaga atctggcgca atcagaatac gcattatttt cccctccgtt
     5821 ccaagatcag ttctttttcc agctggtatt ggtctccatt gacaaaaata ggtaatgttt
     5881 ctttcgtctc tttttttatt actatttgtt tttttgtcaa aacaaatagc aacctgtgat
     5941 ttttccaaat aaaaggaaaa gaaatttttt cccatgctga aggaagtctt ggagaaatag
     6001 aaagagttcc attcgttact gtaatacctg aaaaaccaaa tataactgct agccatagtg
     6061 ctcctaatga agcagcatga attccgtcat ctgatgaatg cggatctggt cctaaatcaa
     6121 tcaggcacgc ttcttggaat aaatgatacg cccattccat ttcttggata cggcaagcct
     6181 ctatggcgtg aatcgcttta ctcaacgatg agtcgtggat tgttttgttt tcatagtaat
     6241 gcaaattctt agaaacgatt ggttgagaaa aatactcagg taataagtat aacagcatga
     6301 caagatctgc ttgcttgctg acttggagtt catttacttc gctacgggca taatcaagta
     6361 aaatagactg gctgccagga cgttctttgt aagtggtcaa atcaataact ggcttactga
     6421 gatacgtgtc atcttgcgga atcagctgtt ctttgttagg cactggcaaa tataacttat
     6481 ctaaaaaatt ttgacattct ttcaaaaaaa gcggatcgcc agcttgatat ttaacagcta
     6541 aggccacatt ataatgcgcc agatagttcg tatatgcatt attgtcgata tattctgtgt
     6601 attcatctgg accaatgact ctgtgtatct ctaaatgatc atcgactttt acagctctgc
     6661 tcagccaaaa agctgctgtt tcatgaatga gcgtttttcc ctttgtttct aaaaacgatt
     6721 gatcctctgt tgcttggaca tactcttgaa cggcataagc aaggtctgca ctgatatgat
     6781 gttctgcggc agctgaagca acttcttgtc ttgttccggt tttgatattc aatgcagcaa
     6841 atttgggtgt ctcttcctga ccagtgtgtg cgctttccca tgggaaaagt gcaccttgat
     6901 agtgataatc tcttgctttt tgccgtgcgc cttctaatcg atcataacgg tacagcagca
     6961 aattctttgc tacttcagga aactgatata aaaagaaagg caggataaaa atttccgtat
     7021 cccagaaaac atgcccttta taaccttcgc cagttagtcc cttcgcccct acactaacac
     7081 ttggatcatt gcggggagtc ataatctgta aatggtaagc agcgaagtcc atcgctaact
     7141 gatcgaaaga agaatcgcct tggatcgtta tccgatgctg atgccaaaaa tctgtccaat
     7201 aagacatcga ctgctctaaa atttctgtat aactaacgct tttctgggct tgggcaatac
     7261 ttttcttaaa cgggtctgtt tgctgaagag aggtagagag cacgatgatc ttctccagcg
     7321 taaaggacgt attttttctg atcttttctg aaaaggaagc ggtgatccgg cgattttttg
     7381 cttggaatac acctgcttta ttgaatttag ctgcaatccc aatatcaatt ttactttctg
     7441 ttgtctggta ggatgcactg atcaaatcgt caccaaatac tcgcagttct ttttcaacca
     7501 actgctgtgt accaaaattg gtttgctgtc catcgatacc cgttttcaca tctacttggc
     7561 agtcttcggt caacggcttg atgaccactt tcagggctgc ctgatggaga ttattttgat
     7621 cagcaacacg acaagtaatg acttccactt tttttccttg agcagtttca atgagcgcat
     7681 agcgtttaag ctctcccatt tctaaatcta gtgcccgctc gtatgcaaga actttcatcg
     7741 tctcaagaga aaaatgttca ccgtcgattt ttatttccca tctgatgaca tctgggagat
     7801 tcactaactc ggctgattct gctcctaaag gtcggttata tacaccagct gcaaacattc
     7861 cccttacttg attccgatag tcttcctcct ggcttcctct gataccaaaa aatccatttc
     7921 caatggtcat ctgactcgca tacttattga tatactctaa atcaaactgt ttttcttcta
     7981 ctttcataag gtaataactt ctcctgtttc tgccgaacga tataaatttt ccaccagatt
     8041 ctggatgaca tatccttgcc agccatctgc aatcatctga gtctggtcac cgagcgcccg
     8101 attcacaaaa tgagccatac ttagttcatg tgggtcatta actggcgtgg tcttttgtaa
     8161 ggaaaccagc tttccatcta catcttcgaa tagttcgcct ggatacagat tagcacctgc
     8221 ctgatcgcca caaaaagcca cattcagttt gtcttctctg atattcaaag caaacgaagt
     8281 attcagttgg atgatcttgc cgttttctaa ttccagtgtg ccaaaaattg catcttctac
     8341 tgtgaatttg cttggatccc atttcccgaa tttccctgaa ttttttttcg taccaatttt
     8401 ttggaagctg tacgcccgaa cgctttttac tttaggaaat ccagtaatat acatcgctgt
     8461 atcaagcatg tgaatgccat aatcgatcaa aggcccgcct ccttgaagtt ctttgtcgat
     8521 aaacgttccc cagcctggaa caccagaccg acgaagcgca ttcgcttcta cgtaataaat
     8581 atccccgaga acatcaagat gattcttgat cattgttgct tcgtcagaaa aacgatgctg
     8641 gaatccataa gccaaaatct gcccgttttt atcggctgtc tctgccatct ttcttgcttg
     8701 atcagctgtc atagctggtg gtttctcgca catcactgaa gcattagctt cgagggcagc
     8761 caatacatgt tcgaagtgaa agcgattggg tgtacagaca ctcacgatat cgggagaaat
     8821 ctcattcagc atttgtgtaa ctgatgtata cgcatgagaa aatcctgtac gtcggcaaaa
     8881 gtcttctgct cgctggctga ctggatcaac cacagcggcc aattctaaga catctgatct
     8941 tttttgataa taagcagcat gtactttttc tgctacttgt ccagcgccta tgattgctac
     9001 tttcttcatt tatttctctc tcctttgctt atttacttat tgttattctt tctctattct
     9061 ttctctaaat catttaaatg acgcgctgtt tccagacagt ttttcaagta ttgcaatgat
     9121 tcctgataaa ttttcacttc attttctcct cgcaaacgac attcatatac catataacct
     9181 tcatactcat tttgaagtag cgtttgaaaa tggcgagtaa aatcaattgc gccagatcct
     9241 ggttggtagc gatgattatc tgctaaatgg atatgaccca catactcttt ttgcgtagtc
     9301 aatgcttttg aaatatcatc ttcttcaata ttcatatgat aaaaatcagc gatgatctgc
     9361 acatgtttca attgattaga gtcaatgtaa tgacgcgcat ccgctaacaa attgatcata
     9421 tggtcttggt atcggttcaa aggctccaaa taaataaccg tacctgtttc ttcggctact
     9481 ttatctaaat aacgaagtga ttcgctgact gctttatagt ctccttcttt gcttcggggt
     9541 gaaaccatcg gcggtaatcg ataagtgaac attccccaag ctgctgggat aacgattcct
     9601 ttgcctccaa cctcgcttag tgcacgcaaa atctcagcaa tttgacgtac accattaaga
     9661 cgccgttctt cgataaagtc accgatccac ccatcgtagc cgttacaagc tgtcactact
     9721 gggatccctg tttctttgat tgcctgtttg actgtgtcga tattttctat taacaactta
     9781 ccgtcgattt cgtattcttc aaatccacag tctttgataa atctaaattt ttctaaaatg
     9841 tctcttggga aaaatgcttg atcttgcgta ccgaatttca ttgttctcct cctcggactt
     9901 gaacgcccat tttgatactt tcttctgggt gctggtctac ataacgcatg taagcttctg
     9961 cgctttctgc aaatggcaca actggatcaa tgatttcttc acaatccaag taaccgttca
    10021 tcaataattc ccaacatgtg tcctcgattc gtttacggtt ccatcttggg taatctgggt
    10081 ttggttcact agatgctcga gcaaagacga tttttgcatt attgaaatgt gcttcgcgac
    10141 caagattaaa cccagctgga aaaggtttag caaaggcaac ataagaaatg atcccgccat
    10201 agccgatccc tattaaagaa gcttgtaatg cggcagcact gccactcgtt tcaataactg
    10261 aatctactcc acgtttatct gtcaattcct ttagacgaaa accgacatct gctttcatag
    10321 gatctagcgt gtaatcggca ccgtgttttt ctgctaattc tctacgctgc gctatgggat
    10381 cgatcccaac gatggtagta gcacctgctt ttttagctaa ttgaatcgca atttgcccga
    10441 tagcgcctaa accgaagatt gctacagcat cacctgctcg aacatgtgct tcccggatac
    10501 cacctaaagc gaattgagca ggatcgtaac atactgcatt tttccattga tccaaccgat
    10561 caagtttacg tagtttataa ttatcaacac cgtttgtaat cagcgtttca cgaatgggtc
    10621 cataagtgca gactaactct cctttttgat actctgtcac caaactgccc gtttcttcga
    10681 tcgtaccgac aatcatattt cctaattgaa attcgccaaa taccacaccg cgttggcttc
    10741 cttcttctct tggcaagaat aggcgccatt cttctgaaaa ttcttcatcg ataaatggac
    10801 ttaatcctct aaagtcgaca atttctgttc ctggttttgg agtagcgaaa attactcgga
    10861 tacgtacttc gttcttttcg atctcacggt cttcgtaatc tttgaatccg gctattcttg
    10921 gttctaatgc aactaatttt ttcatctttt ctttcctctt tcttttcttt ttatcctttt
    10981 acgccgcctt cgactaaatc acctttaata aatcgttcag ataacgcata cataatgatg
    11041 actggtaaag cggtcaccaa tgaagcggcc atcattcgtc cccaaatgta gtctggtgta
    11101 ctgaataatg tgttcaaacc gattggtaaa gtaaattttt cggaggtcga caggaaaatc
    11161 gaagcaaata aataatcatt ccacgaaacc ataaagcaat aaacgaagac agaaatgatt
    11221 ccagaaatag ccaatggtat aatgatccga ataatgatct ggatccggct aagaccatcg
    11281 atcattgctg cttcttcaat atcagtcgga atcgtgtcaa aataactttt tagcatgaat
    11341 atcgcagtag gaagtgtttg aacgaccatc gtgataatca gtgctgtatt ggtatcatac
    11401 aaacctagac cggaaatgat tttaaataat ggaacaacga tcaaaatacc ggaaaacata
    11461 taaacggtgt aaaagctagc attgattttc gagcgagctt tgaagcgtag ttttgacaaa
    11521 gcgtatgccc cgctgatccc aatcactact gcagttacgg aggctatcaa ggagatcact
    11581 aaactatttt tgaaatacat gatgaatgga aaaatctcag cattgaaaat atcctgataa
    11641 tgttcaaaag tccattcttt cggaaaaata gtttgtgtcg ttgcaattgc ttcttgtgaa
    11701 tccttgaatg atgtcatcag catgatcaaa aatggaaaca aattgacagc taatagcaac
    11761 aaaatcgtcg cgtaaaataa gattttcctg ctctttttat ttttcatttc aagtccacct
    11821 tctttcgtga gagcaagacg accgctgcaa taatgatgaa caatagaatc gatatagctg
    11881 ctgcttttcc aagatcattg aacgcaaagg ctgtctgata caaataaacg cctaagatat
    11941 tgactttatt cgtcagtaga tagacatctg taaacatata gaacatccag atagatcgta
    12001 aaacaatcac agttgctagt actggtttga ttgccggcag tgtcacgatc ttgaacttct
    12061 gccaagcatt tgcaccgtcc atttcagctg cttcataaag cgttttgtcg actgtttgca
    12121 aaatagccaa aaatgaaata aacgcatacg gatagtatct ccagatagca aacaaaacga
    12181 ccataaagaa gctagcaact ggctggtcga accacagcgg tgcttcgttg aaaagctgca
    12241 acctatctac taacagatca ttgacgattc cataactatt attgaacata tatttccaag
    12301 caaaaatcaa agaaatagat ggcgtaacat aacttaataa aatcagtgaa cgcaccgttt
    12361 tcctaaatct gaacttgcgg ttaagcaaaa tagctacggc taatcctaaa gctgtactgc
    12421 ctgctacaac taagaatgtg taagcaactg ttaaacctaa agaacgataa aattcactat
    12481 cacttaaaat ttcaagataa ttgcttaatc cgataaaaac ggcgtctgag ttaggattca
    12541 gcggcatatc gaaaaaactg atctgaatat tggaaagcat tggaatcagc actaaaacag
    12601 ctaataaaag catgcttggt gctaaaagtc ccatggctaa ttttaagtca gaatgtttcc
    12661 ttggacgatt cattgaaacc tccccctgat aatctgccaa tagctatcta cttttttcga
    12721 acaccattgg cagaacttct tgttatttcg tatttttttg tgcgtcagct aaagcttgat
    12781 cgacatcttc gtttccgaca gttacttggt tcactgcttt tccgatcaca cctgagcttg
    12841 tgatatctcc cattttcgtg aaattctttt ccccgactag tccaaagact tgtacttcat
    12901 caaaagcact agcaatctca gatggcagct cgccaaaaga cttgatgact tcattttctt
    12961 tgtaaccatc cagttcgact acttgtttat tcactggttg agcaccacca ggagacatca
    13021 agacccactt ttccatgttt ttcggttgag ataagaaagc tgtgaatgct tcagcagcct
    13081 ctttttgttt ctcgtctaga ccagaagaaa tcgtcaatcc agatactgtg ccatagacag
    13141 cttgatcttt ttgtgttggg atagcaaaac cgatattttc tgagttcccc gcttcataaa
    13201 cagaaggcaa aatgtaagtt gaatagattg ccattggtgc tgttccattc atgaaagcat
    13261 ctttgatttc tgtcacatca ttagagcctg gcatcgtgta ttgggataag ttttgataaa
    13321 acgacaatgc ttctctcatc ttttccgtat cgatcgttac ctcgccttca tcatccaaaa
    13381 catttgctcc atttgacaaa gcaaattgag agaacgcttg ctcactcatt gttccttcag
    13441 cagtaggcat agcaattcca tattgtttat tctctttatc tgtgaaatgt tgagcaattt
    13501 ttaaaatatc atcccaattt tctggttctg aaaaaccagc ttctgataat ttttctttgt
    13561 cataccaaat accttgaacc cagccgctaa ttggtgcagc aatatagctt tttccatctt
    13621 ctgaacgaac aaggtttttg gctccgtcat aataattatc ttctccagct tcctcgataa
    13681 cgttttggac tgccgtctga tcaatcagtt catctttatc catcacttta gcaaaatcct
    13741 gactgacttc cattacttct ggtaatttac cggaacgagc taacgtaacg atttttgtat
    13801 tgaacgctga ttcttctacc ggcacttgct tgattttgat gtctggattt tctttttcaa
    13861 aatcagcaac cagttcattg atcacactta atcgttcctg ttcgacagaa gagtgcatga
    13921 attgaatcgt tgtctgttgt gattcgttag agctttgact ttcaccacaa gcagtaagaa
    13981 gaaatccagt agctagcaga caggtagtaa caataatttt tttcattttt ttccacctct
    14041 tattttatta ttttcagcca catatattca tacggctgga atatcaactt tcgttcttga
    14101 ctgcaatgga taatttgtcc agaaaacagg tctaggtaat ctccttttgg taaaagataa
    14161 cctgctgatt gattggaaaa attatggata actaagactt tctcttcctt cgcttcgcga
    14221 ataaaactga taaaagaatc tgctgagtcc agtaagtaaa tcaaactatt cggatggaag
    14281 gctttttctt tttttcgaat agatagcatc tgggtcaatt caccatatac tgctgttctt
    14341 aatggatctg tctgcaactc tttctcaata tctgctaaca aaaatttttg ccgattgatt
    14401 tttcgattct ctcctgtttt ttctacgcct ttgtaatcat ttcgacttcc cagcacactt
    14461 tgaatataaa ttgccggcac gcctggtaac gttaccaaaa atgaatgagc agctaaaaag
    14521 cgtttgcttc tccattccgt cgtatctgtt ggagaactta acgcatctag atacgtagcg
    14581 tttatctcat atggactggt cgttccatct gggtttttct tgtagtttac tcgggcaccc
    14641 tctttcttca gctgttccac taattcaagg atcgtttttt ccggcagaat acctcgtacc
    14701 ggattcaatc cgataccgtc atgggaggct aaaaaattaa aaaaagttgt ttttttcgat
    14761 gcgaaatcga tggtttttaa ccattctttc aacttacttg tattacccga acgaatcgct
    14821 tgaagggtca aaggtggtag cgaaaactga tagaccatct gtgcttcatt ctcgccattc
    14881 ccaaaataac tgatattatc tttgtgtggc acatttgtct cagtgatcaa taccgttcct
    14941 ggagctgctt catcagcgat tgcacggaat aattggatga ttttatgcgt ttctggcagg
    15001 tgtatacaag aagttcctag ttctttccat aaaaatccca cagcgtccaa gcgaataaat
    15061 gaagcgcctt tttctaagta aaacaaaaga atatcgatca ttttcaataa aacttctgga
    15121 tttttaaaat tcaagtctac ttgatcttcg ctaaaagtcg tccatacgtg tttttctttc
    15181 ccgtttttgt caatgaacgt tgtaagtaac gggctggtcc ttggtctagt cacgctgctt
    15241 gtatctgtat ccagtggcaa atcaataaaa aaatctttgt acgtatcatt caagtttaaa
    15301 tattcctgaa accaagtact ttcggcagac atatgattgc agacaaagtc gaacattaac
    15361 cgtgtttcgc ttctcatttc ttctatatct tcccatgtgc ccaaacggtc gttgattgcc
    15421 tgataattta caacggagaa accatcatca gatgtatatg ggaaaaatgg caagaaatgt
    15481 acaactctaa atgtatctgc caaatacttt tgataaaatt tcttaaatgt acgcaaagtt
    15541 ggttgctgct cttcaaaaaa ttgatcccca taagtaatca agaaaatatc ttcttcgtcc
    15601 caatgcagtt tgcctgcctg gcctttcttc tgctgataaa cactgacttt ttgttcaatc
    15661 atagaggcgg ttttctcaga caaatctgag tcgcgataaa tcgcttgtaa aagttttgta
    15721 tacatcggat tcccctttct tttttgggag cgttcccaac gatttgatca tattatggaa
    15781 aacgcttact gtcaatagca tttttttaaa taattttgat atacacaaaa atacaaataa
    15841 gaaagcttat gtatcaataa ttaatagctt cttaaaaaaa tatggtctct catgatcatg
    15901 caagctattc ctaaattttc aaaatcatag acaaaaaaga atgtctattg tactatggaa
    15961 ttattctaaa acgctcccaa aaaggaggtg catataaaat tgaaacctac tatttatgac
    16021 attgcgaaaa aagctaatgt ctcaaaatca actgtctcca gagtattaaa taaccagcca
    16081 aatatctctg ataaagcaaa agcaagtgta cttcaagcaa tcaaagaatt gaattatgaa
    16141 ccgagcaaaa ttgcaagagg actgtcagga aatggttttg acgcgattct agcattatct
    16201 catcgtactt ctcatacgac ctatggcaat cctttttttt cagatgttat tcaatccatt
    16261 tctgccgttt ctgaacaaaa taacttcgac ttgattctac aaacggcaaa aacaccagaa
    16321 gaagagctag aaaaatgcgc gaaaaagatc caagaaaaaa tgatccgagg aattattatt
    16381 ttaagctcta cgatggatga aacacttctt tttgaattgg atcaatacaa tattcctatt
    16441 gtggtaatcg gaaaagtcgg aaacgactac acgaacatct actcagtgga cacggataat
    16501 ttccaggata gttacgattt ggtggaaaca ctgatcaaga atggacaccg tcatatcggc
    16561 tgtctccatg ctccgacaga agtttatgta tccaatgatc gtctcaatgg ttaccgtcaa
    16621 tgcttatttg atcaccacct agatatccgt aatgaatgga ttatagacgg cggctttcgc
    16681 ttagaagata gcatggcagc aatgaatgat ttaatgaagc tacgagaaag accaactgcg
    16741 attttttcta ccgatgcatt aaaatcattg agtatttaca aagtggcaga acaatctgga
    16801 aagcagatac ctgatgatct ttcgatcgca ggattcagtg atcccttatt gtcctcccta
    16861 ttttcgccac agttgactcg gatagacatt ccgacaaatc agttaggaat caaagccaca
    16921 gaacttttat tccaactaat ccaccaccaa taccctgaag aaaaaagaat cattctttca
    16981 accgagatta ctctcacaga ttcgatccaa caacaagaaa tgtagaacag aattataaaa
    17041 gaacagaaac actgaggata agtcagttac tctgttcttt tttcaatcac tcatccctcg
    17101 ttaccccctc ccggtatttt agcgaatttt tcttattttc catctgtttt agatagctgt
    17161 ggataactat aatgtttgtg ttaaactatt ttttccacag ggaagaaaaa actattttta
    17221 accacgttgt gtataagttt ttatagttcg tttttttaaa cacatttacc cttatttcaa
    17281 tccatgttat ttggggatac ttatctctaa aacataaata gaataacaga catgtctact
    17341 ggttttgttt tattcgagga attattcaat aatagctagc aaaatattaa aaataaccgc
    17401 tctatcttcc catcaattta ttttgcattc aaaaaatgat ctatctttac ttttgttgat
    17461 tgacttctct tggaagatga tcgttccgat accttaattg gatacgaacc gatgttgtta
    17521 agatcctttc ccacttttct tctagttaga caaattattt tagacaaacc aaaaaagagg
    17581 ttgtgacaat aatttgtcac aacctctttt ttaaaatatc tattttgttt gattgttcat
    17641 tgcgtcttct gcagccattt gcgcttcaat atctgaaata ctgtagacat tttcgcttgc
    17701 tacaccgact tcttttggtt ccatgtcacg ataacgttgc ataccagtac cagctgggat
    17761 gatcttacct ataataacat tttctttcaa accaagaaga ggatctttct taccgcggat
    17821 cgcagcatcc gtcaagacac gagttgtttc ttggaatgat gcagcagata agaaactatt
    17881 tgtttctaat gatgcttttg tgatacctag taagacaggt cgagaagttg caggaacgcc
    17941 tcctgagact agcgtattgt agttttgatc tttaaagtct gcgatgtcta ataatgtacc
    18001 tggtaagata tctgtatcac ctggatccat tacacgaact ttacgcagca tttgacgaac
    18061 cattacttcg atatgcttgt cgccgatttc taccccttgc atacggtaaa cacgttgtac
    18121 ttcacgaagc aagtagtttt caacagataa tacatcgcga acttgcaaca attgttttgg
    18181 atcgattgat ccttctgtca atggtgcacc acggtggatc atatcgcctt ctgctacttt
    18241 catacgtgct gtataaggaa cagtatacgt acgtgtatct gtttttcctt tgattgttac
    18301 ttctttggta cgtgttgcag gatcttctga gatatcgatg acatcccctg ttacttctgt
    18361 gatcactgct tgccctttcg gattacgtgc ttcaaagatt tcttggacac gaggaagacc
    18421 ttgagtgata tcgtctccgg caaccccacc tgtatggaat gtacgcatcg tcaactgagt
    18481 accaggttca ccgattgatt gagcggcgat cgtaccaact gcttctccga cttcaacgtc
    18541 agagccagtt gcaaggttgc gtccgtaaca atgtttgcag acaccatgtt ttgtattaca
    18601 tgtgaagaca gaacggattg tcactgtttc gacacctgca tcaacgattt gttttgcgat
    18661 gtcttcggaa atcaattggt ttcctgcaat gatcaattca tttgtttcag gatgacgtac
    18721 ttctttacgg gtgtaacgtc ccactaaacg atcttctaat gattcgatga tttcatttcc
    18781 ctcgcggatg gcttggattt caagacctcg gtcagtaccg caatcttctt cacggatgat
    18841 tacatcttgg gccacgtcaa ccagacgacg agtcaagtaa cctgaatcgg cagtcttcaa
    18901 ggctgtatcg gtcatccctt tacgagcccc gtgagttgag ataaacattt ccaagacgga
    18961 tagtccttca cggaagttcg aaatgattgg caattccatg attcgaccat taggagcggc
    19021 catcaaacca cgcattccgg caagctgtgt aaagttggaa atgttaccac gagctccaga
    19081 atcagacatc atgaagattg gatttttcgc ttccaaacct tccatcagtt tttgttggat
    19141 gctgtctttt gcagcattcc aaacagcaat gacacgttca taacgttcgt catctgtgat
    19201 cagaccacga cggaattgtt ttgtaatagt ttcaacttgt ttatgggcat tttcaatgat
    19261 ttcttgtttt tcattcagta cactgatgtc agcgatccct actgtgatac cggcatgtgt
    19321 cgaatgtttg taccctaagt ctttcatacg gtcaagcatc ttagaagttt ctgttacttt
    19381 gaatcgtttg aagacttctg cgatgatgtt tcctaagttt ttcttcttga acggtaatac
    19441 taattcttgc tctttgatat gtgcaggaat atcagtacca gcttcaacaa agtatttgtc
    19501 cggtgtttgg acggtcaagt tgaagtctgt tggttcattc agataaggga attcaggagg
    19561 catgatctcg ttgaagatga tcttaccaac tgttgtgatc atcgtacgtt ctttttgcca
    19621 ttcagtaaat ggtttttcac ctaatgagtt agggttcaca ccgatacgtg aatgtaaatg
    19681 aacatatccg ttgcgccatg cgataacggc ttcgttttga tctctgaaga ccattccttc
    19741 gccttcgcgt ccttcttctt ccattgtcaa gtagtagtta cctagaacca tatcttgaga
    19801 aggagtaaca actggtttac catctttagg gttcaagatg ttttgagcag ctaacatcaa
    19861 catacgtgct tctgcttgtg cttcttcatt caatggaacg tggacagcca tttggtctcc
    19921 atcgaaatcg gcattataag cttcacatac aagtggatgc aaacggattg cgcgtccttg
    19981 tactaaaact ggttcgaatg cttggatacc aagtcggtga agcgtaggtg cccggttcag
    20041 caatactggg tgttccttga ttacgtcttc taaaacatcc catacttcgt cttcttgacg
    20101 ttcgatttta cgtttcgcat ttttgatgtt tgaagctagt tcgcgttgaa caagctcacg
    20161 catcacgaat ggtttgaata attcaatggc catttctttt ggaagtccac attggtacat
    20221 cttcaagaaa ggtccaacaa cgataacgga acgacctgag tagtcgacac gtttacctag
    20281 caagttttga cggaaacgac cttgtttccc tttcaacata tgagaaagag atttcaatgg
    20341 gcggttacct ggtccagtaa ctggacgtcc gcgacgaccg ttatcgatca atgcatctac
    20401 tgcttcttgc agcatacgtt tttcattttg aacgatgatt ccaggtgcat tcaagtctaa
    20461 caaacgtttc aaacggttat tacggttgat tacacgacgg taaagatcat tcaagtcact
    20521 tgttgcaaaa cgtccacctt ctaattgaac cattgggcgt aaatctggtg gaataacagg
    20581 gataacgtcc ataaccatcc agcttggttg atttcctgaa gcgcggaatg cttctaaaat
    20641 atccaaacgg cggattgcac gtgtacgttt ttgtccttgt gcagatttca attcttcttt
    20701 caattcggct gcttctgcat ctagatcaac attatcaagt aattgtttaa tcgcttctgc
    20761 acccatagca gcttggaatt cttgtccata ttgttcacgt ttttcgcgat attcgcgttc
    20821 tgtcaacaat tgttttttct ctaaattcgt atttcctggt tcgatgacta catatgaagc
    20881 aaaataaatg atttcttcca aagcgcgtgg gctcatgtct aatacaagac ccatacgtga
    20941 aggaatccct ttaaagtacc agatatgtga aacaggagct gctaattcaa tatgtcccat
    21001 gcgttcacgg cgaactttcg aacgagtaac ttccactccg catcgatcac aaacgattcc
    21061 tttataacgg atacgtttgt attttccgca ggcacattcc cagtcttttg taggaccaaa
    21121 aatccgctca cagaacaacc cttcgcgttc aggttttaag gtacgatagt taatcgtctc
    21181 aggttttttt acttcaccgt aagaccagct tctgattttt tcgggagaag ccaaacctat
    21241 ttgcatactt tcgaatttat ttacatcgat caaaaggggt tccctccatt tcatttaatg
    21301 gcaaaccgca agacggctga tcttcgaccg ccttgcagct catagaccgg attagtctaa
    21361 attatcttct gcggtttcaa agttttggat gacatcgtct ttttcatctt ccacttgttc
    21421 agcagctttc ttttctaatt ctttggcagt ttgctgttcg gcaaattttg tcaaagcatc
    21481 aacagtgatc aaatcgtcgt cttcatcgtc catgtcgcga agttcgatct ctgtttcttc
    21541 gatatccaag acacgcatgt ccagacctag tgattgcaat tctttcacca atacgcggaa
    21601 tgattccggt acacctggtt ttggaattgg ttcacccttg acgattgctt cgtatgtttt
    21661 cacacgtccg actacgtcat ctgatttgta tgtcaagatt tcttgtaaag tataagccgc
    21721 accgtaagct tccagtgccc atacttccat ttcaccaaaa cgttgtccac caaattgagc
    21781 tttacctccc aatggttgtt gtgtaaccaa tgagtaaggt ccgattgaac gtgcatgcaa
    21841 tttgtcatcg accatgtgag caagtttgat catgtacatc acaccgacag acacacgtcc
    21901 atcaaatggt tcacctgtac gtccgtcgta cagaacagtt ttcgcatcgc tggccatacc
    21961 ggcttcacga actgtttccc atacgtcttc atcacttgca ccatcaaata ctggcgttgc
    22021 tacgtggata cctaactgac gtgcagccat acccaagtgt aattccaata cttgcccgat
    22081 gttcatacgt gaaggcaccc ctaaaggatt cagcatgata tcgattggtg ttccatcagg
    22141 taggaatggc atatcttctt ccggcataat acgggataca acccctttat ttccgtgacg
    22201 accggccatt ttatcccctt catggatttt acgtttttga acgatataaa cacgaactaa
    22261 catgtttacg cctggtgaca attcatctcc agcttcacga gtaaagattt tcacatcgtg
    22321 aacgataccg ccgccgccat gtggtacacg taatgatgta tcgcggactt cacgagcttt
    22381 ttcgccaaag atcgcatgca atagacgttc ttctgcagat aattctgtta ccccttttgg
    22441 cgtgactttc cctacaagca aatcgccatc ttggacttct gcaccaatac ggatgatacc
    22501 catttcgtct aaatctttta atgcgtcttc cccgacatta gggatttcgc gtgtgatttc
    22561 ttcaggtcct aattttgtat cgcgggcttc tgattcatat tcttcaatat ggatagaagt
    22621 gtatacgtca tcttttacca aacgacggct catgatgatc gcatcttcat agttgtaccc
    22681 ttcccaagtc atgaaaccaa ctaaaacgtt ttggcctaga gccatttcgc cttgttccat
    22741 agatggtccg tctgccagag tatccccttt ttcgactttc tcacccaaat gaacgattgg
    22801 acgttggttg tagcttgttc cggagtttga acgacggaat tttgttacat cgtatttatc
    22861 taatgcaccg ttgtcgcggc gtacgcggat ttcagaagca tcaacgtatt caacgacacc
    22921 gtcatgttta cataacaaag cagctcctga gtcatgcgct gatttgtatt ccataccagt
    22981 accaacccat ggtgcttgag gattgatcaa cggcactgct tgacgctgca tgttggcacc
    23041 catcaaggca cggttggagt catcgttttc caagaaagga atacatgctg tcgcaacggc
    23101 aactacttgt ttaggtgata cgtccatgta gtctacttta tcaatagata cttctaagtt
    23161 ttcactttga gcacgagcca taacaacgtc ttgagcaaat gttccatctt cattcaatgg
    23221 gctgtttgct tgggctacga tgtaatggtc ttcgatatca gctgtcaagt agtcgatttg
    23281 gtcagtaaca cgacctgttt cacggtctac acgacgataa ggtgtttcga taaatccgaa
    23341 tttatttact ttcgcataac tggacaaact attgatcaac ccgatgtttg ggccttcagg
    23401 agtttcgatc ggacacatac ggccatagtg ggagtagtga acgtcacgaa cttcataacc
    23461 ggcgcggtca cgagtcaatc cgccaggtcc taaggctgaa agacgacgtt tgtgtgtcaa
    23521 ttcgccaaga gggtttgttt gatccatgaa ctgtgacaac tgagaagaac caaagaattc
    23581 tttgatactt gccacaactg gacggatatt gatcaattgt tgaggtgtca atgtttcagt
    23641 atcttggatc gacattcttt cacgaaccac acgttccata cgtgctagcc cgatacggaa
    23701 ttggttttgt aaaagttcac cgactgaacg gatacgacga tttcctaagt ggtcgatatc
    23761 atcgacattg ccgatacctt ccatcaagtt caagaaatag ctcattgaag caatgatgtc
    23821 ggctggacga accgttttta cagctgcttc tggatagccg tttccgatca cgtttacttc
    23881 acgttcaggg tctcttggtg aaaatacttt gatgacttgg acagtcattg gatctgtgac
    23941 cacaccgtct tctgatggat agtaagtcac tgaatttagg ccattatcaa tgaaaggagc
    24001 tagtgtttcc atgacttggt gagtcagaac tgttcctttt tcaacgatga tctcgcctgt
    24061 ttctggatca actaatgttt cagctaatgt cagattcaat agacgtgttt tcaaatctaa
    24121 ttttttgttt actttgtaac gaccaacgtt tgctaagtcg taacgttttg gatcgaagaa
    24181 acgagcattc agcaagttac gtgagctgtc tgctgttttt ggttcgcctg gacgcaaacg
    24241 ttcgtaaacg tctttcaaac cttcttctgt tcttgagtcg cttgcgtttt tatgcaagtc
    24301 tttttcgact gtattgcgta atgtttcgct gtcgccgaag atttcaaaga tcgtatcatc
    24361 ggaaccaaat cctaacgcac gaactaatac ggttaaagga atcttacgtg tacggtcgat
    24421 acgtacataa gagatgtctt ttgcatcagt ttccatttct agccaagctc cacggttagg
    24481 gataacagta gaaccgaatc cttcttttcc gtttttgtcg acttttccat ggaaatagac
    24541 acctggtgaa cggactaact gagaaacgat tactcgctct gccccgttga tgatgaatgt
    24601 tccttgttct gtcattaatg ggaaatcacc gaagaatact tcttgtgctt tgatttcgcc
    24661 agtctcgcgg tttgtcaaac gcaatgttac atgtaatggt gcagagtagt ttgcatcatg
    24721 cgcacgagct tctgctactg tatactttgg ttctttcaat tcataatcta caaattccaa
    24781 agatagattg ccattgaagt catcgattgg caaaatgtct tcaaacattt ctctaagtcc
    24841 ctcatctaag aaccattggt aagagtctgt ttgaatttcg atcaaatttg gtaattccaa
    24901 cacttcactg attcttgcga aacttctacg ttcgcgatgt tttccgtatt ttactacgtg
    24961 tccagccaag ctcttcaccc ctctaaaatg tcattcaaaa agactacccg atcaattgtt
    25021 acaataatat ttcaaatatt atttttaggt aacaacagac attttttgcg gcttttaggc
    25081 aaaaaaaaac caaaaataga acattctctt gaaaccttac ttcgtgagct tctacttttg
    25141 tttccttata ttaaagccga aacggacaat atttcgtttc tgccttttct tcatcagata
    25201 gtttttgcaa cttcatatac tacacttatt ttctataaaa gtcaacactt cctggcgttt
    25261 cttctgcttt ttcgcaacat tttcttaatg ttttcaattt tatgttttca attatctgac
    25321 aattcttaat tgacagacct ttttatctcg gttatacttt agaaaattca ttttgtggag
    25381 gaacttctat gcgaaccaac atcaaccaaa tcgcaccaac acaactgaat aacttttact
    25441 ttagctactt tagataggtt tgtattcatc atgatggata caaacgttaa acgacagttt
    25501 gtatctatga tggctaaaga actttgtatt gcagcaaaaa gccacgtaga caaaatgcta
    25561 agtggctgag cagtgaaaat acaaagtaaa agtatcaagc attctacttt ttcaatttat
    25621 tttccgactt ttcaatccat ttggacattt tgtctgaatg gattttttgt ttcccaaaat
    25681 taaggaggaa aaagaaatga aaaaaaatat aatcatcgga ttaggcgctg ccctgctact
    25741 agctttagga ggttgcgcac aaaaagacaa ttccgcagag gcatcagatg gacaaaaaac
    25801 aattggcgta ttgcaacttg tacaacataa ctcgttagat gctgcctata aaggattcaa
    25861 agaaggatta gcagaagaag ggtataaaga aggcgataat ctaacaatcg attatcaaaa
    25921 tgcccaaaac aatcaagaca acctgaaaag tatgagtgag aaactcgtca aagaagatcc
    25981 tgatttgcta cttggaatcg ccactccagc agcacaatct ttattaaatg aaacaaccac
    26041 tatcccgatg actgtcacag cggtcacaga cttggaacaa gcccatttag tcacatccaa
    26101 tgaaaaacct ggcggcaatg tgactggcac gacagatatg gtgccaatcg aaaaacaaat
    26161 cggcttactg ttaaatatcg tgccagacgc caaaacaatc ggcatcatgt ataacaacgg
    26221 tgaagcaaac tctaagatcc aagctgattt ggcagaaaaa gaattgaaaa aagcgggcgt
    26281 caaagtcaaa gtactgacag caaattccac aaatgatgtc caacaagtga cgaaaagtct
    26341 agctaaagat gtagatggaa tctatattcc tactgataac acgttcgcaa gtgcggcaag
    26401 tgttgtcggt gaagtcgcaa aagaaacaaa aacacctgtc gttgctggcg cagttgatca
    26461 agtcaaagac ggcggtctag caacagtagg aatcgactac gaaagcttgg gcaaacaaac
    26521 agggatcatg gcagcaaaaa tcttagacgg caagaatcca agtgaacttc ctgtcgaaac
    26581 agcgaatgat ttggaactgt atgtcaataa agacatggcc aaagcattag gcatcaatcc
    26641 agacagcatc aaagaagctg aataaaacac aggaggattc tcatgacaaa tttgctctct
    26701 cttttcttat catctgcatc gcaaggggtc ttatgggccc tacttgcgat tggtgtatac
    26761 gtcactttcc gtatcttgga cattgccgac ttgactgctg aaggaagctt tcctttaggt
    26821 gcagggatcg cggcagtaag tattacaaat ggctatcatc cattgacagc ttgtcttcta
    26881 ggctttttag ggggtgcggc agcagggctt gtttccggac tgcttcacac aaaattgaaa
    26941 attcccgccc ttcttgcagg gatcatcacc atgactggtt tatattctgt cacatcccgt
    27001 gtgatgggtg cgccgaacat ctctttattg ggtcagccaa cgatctttca ttgggtcgag
    27061 tcattcggca taacaaaaga caacgctgta ctgatcgtcg gtctgctttt tgctttgatc
    27121 gttgtatgtt tacttgtttt gttcttacgt acagaaacag gacttgctat tcgtgcaact
    27181 ggcgataatc tggcaatgag cgaagcaaac gggatcaaca cagataatat gaagatcatc
    27241 ggttatatga tttctaatgg atgcattgct ctttctggct ccttacttgc gcaaaacaac
    27301 ggctttgctg atttaaattc tggtattgga acgatcgtaa ttggacttgc ttctattatc
    27361 atcgcagaag ttttgttacg taaccagcca ctatttctcc gtctcttgac tgtcgtttta
    27421 ggtgcggtca tttatcgttt tattttagcg ttagtcttcg aactgaatgt tgaaccaagt
    27481 gattcgaaac ttgcttctgc tttcgtgcta gtgatctgtc tttctttccc gcagatccag
    27541 caaaaattcc atttacctca aaaaaagaaa ggcggtagtg tcaaatgaat gacgtcttaa
    27601 cattggaaaa tctccatcat acctttgaaa aaggaacgat caacgaaaat catgtcctga
    27661 aaggcattaa tctttcctta gatcccggcg acttcgtgac gatcatcggt ggaaatgggg
    27721 ctggtaaatc tactttgctg aacagcatcg ccggtacatt ttctgtcgat cagggtcaaa
    27781 ttttattgaa tggaaaaaat atcacgaaaa aatctgttgt cgaacgttcg aaatccatca
    27841 gtcgcgtatt ccaagatcct aaactaggga cagccgttcg tttaacggta gaagaaaatc
    27901 ttgctcttgc tatgaaacga ggaaaaaaac gcggcttctt ccgtggtgtc aaaccacaag
    27961 accgaacatt tttcaaagac cagctggttc ggctaaattt ggggttggaa aatcgtttat
    28021 cctcagaaat cggtttgctg tctggaggac aacgtcaagc tattacgtta ttgatggcca
    28081 cattacagcg tccagaactg atcttattag atgaacacac tgcagcgctt gaccctgcta
    28141 cttccaaaac ggtgatggaa ttgacagaaa agctgatcac tgagcagaat ctcactgctt
    28201 ttatggtcac tcatgacatg gaagacgcga tccgctatgg gagtcgactg atcatgctgc
    28261 atcaaggaag gatcgtcgta gatatccagc aagaggaaaa acagcagctc acagtgcccc
    28321 aattattagc gttgttcaaa caaaacagcg gcacggcatt aaaagacgat caagtacttt
    28381 tatcttcata atcagaaaga ggatgggaca aaaaatgaac gcccaccctc ttcttttttc
    28441 tctttccttc tttcgttttt gctttatgta tcaaccgttg tttcttcgaa aactattttg
    28501 ttctctcctt cttcctgata gaatggatgg gaaaggagct tgatgccatg acaacgaaag
    28561 acaaggtact tcaattattg aaaaagacac cagattttct ttccggagaa aagttggcac
    28621 agcaactgga agtttcccgg acaagtattt ggaaagccat caaagaattg gaaaaggcag
    28681 gctatcgttt tgagcacggg cctacagggt atcgttacct gccctctgac gtactagatg
    28741 caaaagaaat ccagcaagag ctacggtcgt ttattcctga tttgaaagta caaacgatgt
    28801 tgacttctga atctacgatg aaagatgcca aactggcagc agctcaagga gattctgttt
    28861 cgaagttatt tgttgctgat acacaagaac aagctcgtgg acgttttgga cggccttttt
    28921 tcgctgaacc tggacgagga atctacatga gtctcttgct ccatccagac aaacggtttg
    28981 atgaattgcc tcaatatacg atcatcgcag ccagtgcctg tgtgaaagcc attgaatctg
    29041 taaccggtcg ttctgcttcg atcaaatggg tcaatgatat ctacatggat ggaaaaaaag
    29101 tctgtgggat tttatctgaa gcagtcagtg atatggaaag cggcaggatc agtcatatca
    29161 tcattgggat cgggcttaat ttttctgttc ctcaaaatca ttttccagct gatctccaag
    29221 aaaaagccat ctctgtcttt cccgacggac aagctagtgt cacaaggaat cagctaatca
    29281 gcaaaatctg gcaagaattg ttcacttatc tttctcaccc agaaaaagcg ttggacttct
    29341 ataaagaaaa atcattcgta ttgggaaaaa ccgtgtcgtt caatcaaaaa ggaacgactt
    29401 atgtcggtct tgcaaaagaa atcggtgatc atggcgaact gatcgtccaa acaaatgaac
    29461 agaagatgag tttgtcttct ggcgaaatca gtctcacatc tatccgtacg caataattat
    29521 cagatttcac aaaaggacac ctgatctcat acagtgtcct tttttctgaa ttctcttcaa
    29581 aagactctcc ttattctatc agctgacagt ttctctatcc tctagaaaaa ggtattctaa
    29641 aaatatctat aaagcatggt acactttctt taaatgaatc aatgcaaaaa acaagagagt
    29701 catcagttta cacgatcaaa agagatagca ggccgcttcc tttttcaatc ttatagatag
    29761 accatgggta acgataaaaa caaaaaagaa cttgcgactt attttgccgt aagttctttt
    29821 ttagctagtg ccttaatctc ttaatcccaa caaacgtctc gcatagatca cctgaccaga
    29881 gtgcatagca gcatcatcaa taatagaaac gagacgcatt cctcgtgtga ctggtggtgt
    29941 ccagttctcg tcaattactt catctagctc ggaaggttcc agccttctta agtaagaaat
    30001 agcaaaatca gcagctcctc gcaagtatcc tagcagatct tctatttgat tagcttggat
    30061 ctgctttgct tgttccagac tatgcttcca atcttgttcg ttatctgcta tcgtcatcgg
    30121 aaaccggctt tcccagtctt gactatgcca aattggagaa gttcctgcta aatcagcaat
    30181 ctggaaatct aattctcgag cggtatgcca agccagccaa gtcattgatt tgatctgcgg
    30241 ggctctatct tccactggaa aacgattggc ctcctcaata gagacgcctt caaacaaacg
    30301 ttcaaaccga tcgtatgccc gatccacact ctcgcatagc atatctaaat aatccattta
    30361 ttttcctcct ttttatttat cctacttact ttttcctaat tctaggatac ctacttatat
    30421 gttactacac acccttattt tttacacttt aacagtcacc atcatcaata gtttggagat
    30481 tgaaagaaaa agatagtgtc gaactatcaa ttgaacaaga agcaacaata tgaacgtttc
    30541 attaatattc tttaaataaa caatgatttt tcaaacgaac agtttaagac taggagaaaa
    30601 agagtataat aggaaaatgt ttgaaaggaa aggaagggga aaaatgaaaa aaagggcaag
    30661 tttactagtc ctagttgctt tgttgttcaa tatcttttcg tatggtgtgg ccgtttcagc
    30721 ggaaacatac attcctaaag accctgggaa tatttataat gatctaactg gtaactatgg
    30781 cttgttagga attgctagtc aattccacgt atttgctaaa aataagacaa ctgtgaatgc
    30841 acatacagac ggaaatatag caacacatga acttgatgca aaaaataatt ttggtacaga
    30901 gcttcatgaa ggtttattga accaagaaat aaattatata caaaaaactg attctttcgc
    30961 taattcttca ggcataccta caggtagcac aagaatgaat aaatttgtcg ttggcagtaa
    31021 cgtggatgta gcacttcaag atggtcatcc tacagtcaat ggatccaggc ttgatcactt
    31081 aactccagat gatttttata aagatcgtgc tgggcatgaa tatattgatt tcgagcagga
    31141 atttgctaaa ttgaatgtag cagcaaatga tcttgcaacg atcactccag ctaaaacata
    31201 tactgctgca gattttccag acatgaacaa tcggacaatc gatttaactg atttatcaga
    31261 taccgggttt ttattggtaa atatcgatgc agaagtgtta acgatgaata cgccacttca
    31321 aatcattaat ccaaatgatc aagtagttgt atttaatgtc atcaacagtt cttctgcatt
    31381 gaacgtacag tcaccaatca aatacaatga tcgttcaaat catgaaacag aagatttttc
    31441 ggatgcgaat atctcttgga attttggaaa tgagatgact gatttgacaa tcagtgctcc
    31501 ttttcaagga acaatccttg cgcctaatgc tactatccgc attactcaaa accaagacgg
    31561 aacgattata ggaacaaatg tgattttaga tgcagctacc aatcgttggg atcctaacga
    31621 aatatttatc agcgacaatg gtacagatac gacagacaca agcgacagta cagatacatc
    31681 taccacaagt gatagctcag attcatcaac ttcaagcgac agtacagata ctacctctac
    31741 cacaggatac atcagcttca agcgacagta cagatactac ctctaccaca agtgatagca
    31801 cggacacatc agcttcaagt gacagtacag atactacctc taccacaagt gacagcacgg
    31861 acacgtcagc ttcaagcgac agtacagata ctacctctac cacaagtgat agcacggaca
    31921 catcagcttc aagtgacagt acagatacta cctctaccac aagtgatagc acggacacgt
    31981 cagcttcaag cgacagtacg gatacatcta ccacaacaag tgatagcacg gacacgtcag
    32041 cttcaagtga cagtacagat actacctcta ccacaagtga tagctcagat tcatctacca
    32101 ctacaagtga tagcacggac acgtcagctt caagtgacag tacagataca tcctctacca
    32161 caagtgatag ctcagattca tcaacttcaa gcgatagtac agacacgtcg tctaccacaa
    32221 gcgatacacg tcatgcaagt gtctccttct caaaaacaag ttcggataac aggacgaact
    32281 ttaacttaac taataaaaca agcaatgaca atggaaacaa atcaaaaaga gcacttccta
    32341 aaactggaag tcaatcgaat aattggataa cactcgcagg cgttatatta cttgtaatcg
    32401 gtttaagaat cacttttatg agttataaga aatcgaaaag gtaaaaaaat attcaagata
    32461 aaaaagagca acgtcgctaa cggacgttgc tctttatttt tgctttttat cataaataca
    32521 agaactacaa ttcaatttgt caaaaaacac gtagatttcc ttctgagaaa tttatttacg
    32581 tatcgaacct ttccctattc agtctttgcg atccaaaatc agttgggtaa gggaaaagag
    32641 attctctttt gttcgaagag aggtggcagg taatttcttt atttccttca aagccttttc
    32701 tgtgtaagag gccgctaact tcctagcttc ttccacgcct cctgtatgtt caacgatttt
    32761 gcgtacggcg tcgacatctt cttctgtcat tgccgctttc ttctctaaat aaggtagtag
    32821 ctttggtttg tttttttgca aagagtagat caacggtaaa gaatagaccc cttgacgcat
    32881 gtcttctagt acaggtttgc cgatttcctg gctctctttt gtataatcta aaatatcatc
    32941 gataatctga aaggccatcc cgatagaaag tccgatatct cctgcttttt ttgcgaagcg
    33001 ctcgcttgtt ccactttcaa aagcgccaac agaacaactt aattggaaca gttcagctgt
    33061 cttacctgaa atattttcca aatattcttt tacagaaagt tcataattat agcgatcatc
    33121 catctgccct aattcgccat tcaatacttt ttccatactg cgagaattca attggagact
    33181 tttcaaggaa gtggagtaat cagacaatag tttaaaacag cagacaaata aatagtctcc
    33241 tgcatagaca gaaacgacat taccaaactg actacggata ttaggctgac cacgtcgcag
    33301 atccgcttca tcaacgatat catcatggat cagtgtggcc gtatggagca tttcgataga
    33361 agctgccaaa gcgatggctt tgtctcgatc ttgctctggt ccaaattgtg agaacaatag
    33421 ctgataggca ggacgcaaca gctttccgcc ggcatggatc gtttctttga ttgcttgttc
    33481 gacaggtttg tttttcaggc ggacagtttc ttccatccgt tttagtgttt ctgtcaattc
    33541 tttacttaaa gcaggatagt tttcccacat tggatgtagc ttcataaaaa aactccttgt
    33601 gtgacgatta ttttttggta aacattgggc tccatttttg tttggttccc tgctcataat
    33661 ctttttggaa tcgttgaagt gtctgcacat gtcgtaaaag ataattcgct gcgatcccga
    33721 ttgcaatccc tgataaaatc cctaaaactg aaaggactgg caagtacaac atgactgtcc
    33781 atgattgtgc aatgaaagaa gccatcaaaa gctgtccgac attatgcatg aaaccgccgg
    33841 ccgcactaat tccgatgata ctgacacgtt ttggtcctaa ttgcttgacc aataacattc
    33901 caaaataact aagcaaagca ccactcatac tataaaggaa tgtggaaatc gttccgccta
    33961 gcaaagtagt caggaatagt cgtagccaaa gtagtaagaa gctgtctcgt tttttcatgg
    34021 taaaaatggc aacgatcgtg attagattgg ctaagcctag ttttgcacca ggcgcaaaag
    34081 aaaaaggata agggatcata ttttccaata aaccaatgat cactccttgt gcaacaagta
    34141 gcgaaatata aatcattttt tgtaatttac tcatggtgtg tgaaggtcta ataaatcaga
    34201 ctgtcttcgt cacctccatc tgttgaacgg acttcgatca ctaatttatg tggcaaacag
    34261 acgatggttt cgccattttt cgttgcccag cctcgacgta cgcagatctg gtcatcgcaa
    34321 tctgcttctt ttatccgtac tcgatcgcca tctatctcga tcaagttata atctccgtgt
    34381 tcatctttgt aagtatatgt gttgctctct tctccagcca tcaaagggaa tgttttgatt
    34441 tctgtgccat ccacacgcag taccgcttct ttttctgctg ttgcggtgtt ttgctgaaga
    34501 ccaaaaatca tgactggtaa aaaagaaaga acagtcaaaa gcaaaataat aaaaacatcc
    34561 caaggtttga gcagactttt ttcagcaaat tctttaaggc tcatttttgt tctccttttt
    34621 ccagattaac tcacccaatt ttagcataaa aacaagaggt tgtgacacct gtgtcttgct
    34681 ttgagtaata agaacgaaga atagaaaaca gctttccatg ttttctaatt ctttgggctt
    34741 attaccgaga agcagcaggt ggaacaccgt ttataacaag aggttgtgac agaagtgggc
    34801 aacttcaaga aataagaagg aatttacgaa aattactttt caagtttttg tgaaatttcg
    34861 gcttattttt cgaagaagct acttctggaa caccgtttat aacaagaggt tgtaacagag
    34921 gttgtgacac ctgtgtcttg ctcatggagg cttatctcgg gcatcttatt cctttaattt
    34981 tacataaaaa ggaggctgtg acggtttgtc tcagcccctt tctattgaaa tcttgcattc
    35041 aaataacgtt ctttatctat ttatttcttg ccgtactggg aacttggtct accgtaccac
    35101 caattaccta gtgtacgttg tagccatgga attacccagc gatccaaccc aatcgcacgt
    35161 ccggaaccgt tcatcaatgc gaaagcaaca aaaatgaacc aaatgtttac ccagtaaaac
    35221 atgcctgata agcagaacgt gatcaccaat acaatcgttg tcgcactgca tagccatgtg
    35281 aataatccag caatcaatgc taatgccaag gcaatttcaa agaataccat gaatttttgg
    35341 aagaacattg ctacatcatt gtttggcatg atcacttgca tgatctttgt gaaccagtct
    35401 ggtgacttct caatcacagc cattggttct tcaccgtatg cataactcaa accaaaatgt
    35461 gcagcttgag tcgctgcttc tccggcactt gcccctgctc cgctggcagc tgtggttgca
    35521 tcaccagcag cagaagcacc actggcaaca tctgttacat tgtattccca tgtccaaggg
    35581 aacacactgt ttccagtgaa ccatgatcct tcaccaaacc aagtacttgg tttgaacact
    35641 tcaccattcc caatgatttt tttggaagct tcaacgaacc aaactaaacc atagaaaata
    35701 cgaagtggca cactccataa gacattgccg taacgagaag aatgtcctcg agtcacgttg
    35761 cgatcatctt tgatatggaa aaactcatgc attaaatatt ggaacatata ataaccagaa
    35821 cgaatatcaa agaagtattt caaattcacg atatgtttca ttacgatagc taaaaatccg
    35881 cttaaatgga tcttatcaaa taggttagct accccccatt tggcaccaat agaaaccata
    35941 aatccttgat agtttccttt aaatttatgc ttttctccgc ctttgatcga agccacgata
    36001 ttcgctgcgg ctgtgtgtcc tgtttgttca gcagcttgaa cgatctgcgg tgtcggtgtt
    36061 cctgggaatt cttcataaaa gactaaatca ccaatgatat agatgttttt atcttcgtag
    36121 ccttttgcct gcatatattc attggcgatc aaccgctgtc cgcgtgctga ttctaatcca
    36181 aagtcagcag cgtcagaagt tcctttgaca ccagctgtcc aaatcagtgt gtgagtcgga
    36241 atgttgcgtc cgtctttcaa tttgatatga tcagcagcca cttctacgat tggtgcattc
    36301 aataataatt ccacgttgtg cttacgcaaa tagcgttcag cttttgcagc atcatttcga
    36361 tccaacatat tcaagatcgt cggcattgcc tctacgacca tcagtgtgat ttcgtttgga
    36421 tctaatttat aatctttggc taggcgattt ttccagtcga tcagttcccc aatcatttca
    36481 ataccggtaa atccagaacc acagacaacg aaagtcagca tggctttacg cagttcatca
    36541 tctggttcca atgcagcttt tgctactgtc ttctcaatat gttcccgaat ccttacagaa
    36601 tcttcaaatg accaaagggt gaatccgtgt gctttgacac caggtgtacc aaagtcattc
    36661 ggctctccgc ccattccaag gatcagctga tcaaaaggat aggaacctaa tttggtcttg
    36721 acgatttttc gttctttatc gataccgatt acagtgtctg tgacaagttg tacattcttt
    36781 tgacgagcaa acaaatgctg cagatcgtat tggattgctt ctggttctac acgtccgcca
    36841 gctacttcat gcaactcggt catcatagta tggtacgaat gacgatcgat cagagtaatt
    36901 gctacatctt cttttttcag tttctttgcc aagtattttg tagctgaaac accggcatat
    36961 cctgctccta caacgacaat attttgcttt gccattgatc atccgctcct tatagactat
    37021 ctatataatg aatatatgat aattctttta gtttgatact tattacacaa tctccatata
    37081 ttatatagat gttctgttct tttgtctaac tccttttgga tttttttcaa attttaaaat
    37141 aaagcgtttt ttcacgaaat ttgctgaaag aaaacgtttg aaatattaca tgggttattt
    37201 atcaaaaata gttgacttat aggctaaaaa gattagaatg tataatgaat cacaaagaaa
    37261 aattgtggac tagaaatgga atggtggggt attaaaatga agaaaaaacg ttttgtaact
    37321 ggatttgccg tattagcatt ttcagctcta gtgttaggcg cttgcggcgc agatgacaac
    37381 ggaagctcaa actcttcttc tgaatcatct acagcacaat cttcgactgc aaaaagcaca
    37441 acagaatcat ctgcaaaagt tgtagctggc ggagatttgc aagacggcac atataaatta
    37501 gaagaaaaaa attattcaaa tggttaccgt gcagtctttg aaatggttgt aaaagacggc
    37561 aaaatcactg aatcaaaata tgataacgtc aatgaaaacg gcgaatcaaa aacaaaagat
    37621 gcagaataca acaaaaacat ggaagcaaaa tctggcacaa acccagaaaa atacattcct
    37681 gagttgaatg accaattctt aaaagcacaa agcgcaagcg gtgtggaagt cgtaactgga
    37741 gctactcact catctgaaag cttccaaaac tacgcacaac aattgatcca agctgctcaa
    37801 gctggtaaca cagatacaat cgaaatcgac aatggtgctg atttgaaaga cggcacttac
    37861 aagcttgaag aaaagaacta ctctaacggc taccgtgtgc aattcgaaat gacagttgct
    37921 ggcggcaaag taactgaatc aaactttgat tatatcgaca aagacggtaa atcaaaacaa
    37981 gatgatacag aatataatga aaatatgaaa gcaaaaagcg gtacagaacc aaaaacttac
    38041 atccctactc tgaacgacga attcgtcaaa gcaatgggcg aagaagatgg ctcacctgct
    38101 aatgtagaag ttgttacagg tgctacacac agctcacatt cattcatcat gtacgcacaa
    38161 caattagtga atgcagctga aaaaggcgac actcaaacaa tcgaagtaga taatatcgta
    38221 acagaaaaat aatcacataa tcatactaat aaaagttgga gggtgggacg atagccagat
    38281 taggcagtcg tctcaccttt caaaatgaag agaggaaaaa gatgcggaaa aaactactat
    38341 tttccttaat cacactgggc atctctttta tggtgctaac tggctgcagc aactcagcaa
    38401 ataaaacaac cactgaaagt tcagcagcta ccaagatatt gaaagatcca tattctgatg
    38461 aacagttctt gttagggact tacgttcgta tccgtgtgta tgatgaaggc aaagaatcag
    38521 cattgaaacc tgccttcgat cgagtaaaag aacttggtga taaaatcacg atcaatcaaa
    38581 aaggttctga gatcgatgaa gtgaatgagc aagctgggat caaaccagta aaagtttctg
    38641 atgacgtcta cacgttagtc aagcgggcct acgaatatag ccaagattct caaggcggat
    38701 tcgatatggc gattggtgca atcacacaat tatggcgaat cggttttgat gacgccagaa
    38761 aaccttccca agaagaaatc gatcaggcat tgaaattagt ggattatcat aagatcgaac
    38821 taaatgacaa agaaaaaact gtttatctaa aagaaaaagg aatgatcatc gatttaggtg
    38881 caatcgccaa aggttacatt acggacgaag tagtgaaagt cttgaaaaaa caaggagtga
    38941 ccactgccat cgttgacttg ggcggtaatg tctatgtctt aggccacagc ccaagaggcg
    39001 aaaaccaaga ctggacagtc ggcatccaag atccgaacat ggctcgcgga tctgttttag
    39061 gttctattaa agaacggaac aaaacattag ttacctctgg aatttacgag cgttatttag
    39121 aagtagatgg caaaaaatac catcatttgt ttgatccaaa aacgggttat ccgttcgaca
    39181 atgatatcgc aagtgtcacg atcataacag ataaatcaat tgatggtgac gggttgtcta
    39241 cagcagtctt ttcaatgggt gtgaaaaaag gactggaata cgtcgaaagc gaattgaata
    39301 acgggacgga agcgatcttc gtgacaaaag acgataaagt atatgtgacc gatccaatca
    39361 aagacacctt caaattatcg gaggactccc attacacgat gggtgaccgt tctgaactaa
    39421 aataaggagt acgaaccatg acactaaaaa tctttttaga agtagttgaa atacgaacaa
    39481 aggtggctag tgtatttcct tttgcggtag gggtattatt ctctatcgct ttttttcatg
    39541 agatacattg gctaaacact tttttatttt ttattggaat gctagttttt gatttagcga
    39601 ctaccgctat caataattac atggattatg aaaaggctca ttctgaagta tataagtatg
    39661 aagaaaatgt cattggccgc agaaatctat ctcctgtatt gattcgaaac atgattttag
    39721 ctatgattgc atttgttttt gttatcggcg ttattctaac gatcaatacg ggttggcttt
    39781 tacttttgat gggatttatc tgttgtttta ttggagtatt ctatacattc ggaccgattc
    39841 ctttatctcg aatgccttta ggggaaattt tcagtggggt gactatgggc cttggaattt
    39901 ttgccatggt cgtttatgtc aatacattcg gttcagatgt ctatgatctg acagtcaact
    39961 tttcatctgg acaatttgat ttggtaggaa atctttgggc tatagcagca atcgtattag
    40021 cttccttacc cttggtgttt acgattgcca atatcatgtt ggctaataat ttgcgggatc
    40081 ttgaccgtga tattgaaaat catcgctata cactagtttt ttatatcgga cgtcctgcgg
    40141 gaacagtctt attccagcta ttgatgtatg cttgctattt cgtgatttta atggggttgt
    40201 tgagcggtat ctatgaatgg ccgatcttgg tcaccttctt gaccttgcca attgtgaaga
    40261 agcatttgga tcaattcaag caaacgttac cccagcctat cagtttcagc tattccatca
    40321 aaaatatggt cttattcaat gccagttatg tattggggct attactaaca atcattatgc
    40381 aagccattta acagcatgaa gaggttgtga aaaaactgcc ctgcatcaag taataagaac
    40441 agccaaataa aaatagctcc ttatattttt cgtttggttg ggcttattac cgcagatgca
    40501 agcttttgaa caccgtttat caggaggttg tgaaaaagtc gcttagtttc gagtattaag
    40561 aaaaattttg tgaaaatggc tttccacatt tttgcataaa tttggcttaa taccgagaaa
    40621 ctggcttttg aacaccgttt atcagaggtt gtgaaaaagt cgcttagttt cgagtattaa
    40681 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
    40741 actggctttt gaacaccgtt tatcagaggt tgtaaaatca gtgttttgtc ctgagtatta
    40801 gagaaacaaa tggaaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaagg
    40861 acagctgatt gaacactatt tgttcggaaa aagtgactaa ctatgacaca atttttttca
    40921 cagtcccttt tttcacttga tttgattcgt accagcgaac ttgacgagaa ctttcttggt
    40981 ttggtaacta tatggtattc ttttaacatc ctcgtttgct tcttctaatt tatttataca
    41041 aagtcacact tttttaaaca tctgttcttc gatacatttc tatttctttt aaacatcgat
    41101 accaatattt tgaacttaag agtgcatacc aaatggattc atttactctt cgtcagttac
    41161 gaagataatc aaaatctcca acttccctac ttatttcgtt ttgagaatta tcgaagcaat
    41221 cttacataaa taactaaaaa acaaaaaacc agaaaatcag tatactgatt ttctggtttt
    41281 acatggtttg ttcaataaaa agctgttgga actgttaata ttaaattatc gcatcgttac
    41341 gaattcttcc gctcctgttg gatggatggc tactgtattg tcaaagtctt ctttagttgc
    41401 acccatcttg atagccacgg caaaaccttg cagcatctca tcgacaccaa caccaatagc
    41461 atgtaagccg acgattcttt cttcttttcc gacacagatc aatttcattt cgcatttttg
    41521 gcgataatca tttaatgcaa agtacattgg ggtaaagcgt gaacgataaa ctttcaattc
    41581 attttcgcca tatttttcca atgcttcttc ttctgtcaaa ccaattgttg caattggtgg
    41641 atgcgtaaag acgactgtcg gaacaagttt atagtcaaga taagaatctt tctttccatt
    41701 aaataaacgt tctgataaac gtctaccagc tgcgattgca acaggagtca gatctaattt
    41761 accgatcaca tcaccaacag caaaaatatg ttcatccgtt gtattttggt atttatctac
    41821 tttgataaac ccttttttgt ccaattccac atttgtattt tccagaccta atttttcggt
    41881 attcggtaca cgtccaccgg caaaaagtac acaatcacca gttaaggttt caccattttc
    41941 aaatagcacc gtatattcgt cattgttttt agtaatttct ttagcaatat gatgtgcgta
    42001 agtttttatt ccagcttctt ggtacatttg gatcaaattg tccgaaagca ttttatcaaa
    42061 cgttctaagt ggtcgttctt ttcgatatgc ccacatgact tcactaccta aaccacgaaa
    42121 tacacctgaa agttcagccg caatgtatcc agcacctaaa acgattgctc tcttaggtaa
    42181 ctctgttaat tcaaaaaatc catttgaatc aattgcgtat tctccaccag gaatggtcat
    42241 tttacttgca cggcctccag tagcgatcaa gattttagga gcacgatagg tttcaccgtt
    42301 tacttcgatc gtttgactat cgataaaagt agcgtaacct tttatagcct cgacatgatt
    42361 gctatctaat cctctttgat aagcaccgtg tagaaaatca atatattttt ctcgtctttc
    42421 tactagaccg gcgaaatcaa cattttttaa atctgcttgg ataccgtaac ttgaggcatc
    42481 tcgttcaatt gtttccaaaa tcgtacttgc ttgccacata acttttttag gtacacaacc
    42541 gacgttgaca catgttccgc ccaattcatt cgcttcaatc agcaaaactt ttgcgccatg
    42601 catccctgct ctgtttgctg aagcaatacc gccagagccg ccaccaatta cgatgtaatc
    42661 atatatttgc attttgttcc tccttattga agagatcaat caaaaccttt atttaacgat
    42721 cctttttcta cagaaaacaa gtgtaacact tttcttgaat tttgtatgcg aagatgctta
    42781 aaacagggat atatcagctt tttccttatt tacgttttcg gatcatatct ccaggtttca
    42841 ccggctgtgc gactggcata gttaaaatca tcattggatt tggtgctcgg tcaatggatt
    42901 cgccttcttc attatgcata acttcaacgg tttgactgaa atgactgaat cctggaccat
    42961 aaaattcgat ttcatctcct acagaaaaca agtttctctg acgtatcgta gcaatctgtg
    43021 ttgcctcatc ataagataat acttcaccga caaatttata tactgggatt ttacgacgtt
    43081 caccgaataa ttgttcgttt tcagttggtg tattgtagta aaaacctgta gctaattctc
    43141 gttgtgctac tttccataac tcgtcgatcc attcttgctt gcagacatag ttttcaggat
    43201 cttccatata actgtctaca gccgctttat agacatttga caccgtagat acataatgga
    43261 tcgatttcat tcttccttcg atcttgaagc tgtctacgcc gttttcaatc aattctggaa
    43321 tatgttcgat cattgacata tccactgcac tcatcgagaa ttcttcttcc acttcgcctg
    43381 tatcagttaa actgtttcgt tcttgaccaa aaggcatatc gaacaatcca tacttccagc
    43441 gacaagattg agaacatccg ccacggtttg catcccgcat cgacatatgg ttggacaatg
    43501 tgcatcgacc agaataagag atacacatgg caccatggat aaatgcttcg atttcggtat
    43561 ccgtattttt acgaatctct gccacttcct ccattgaaac ttcacgagct aaaacgacac
    43621 gttccaaccc ttcttctttc cagaattcca atgtctcaaa attagttgct gaagcttgag
    43681 tggataaatg gatcggcaga cctggggctt ctgtcgcaca aatttcgatc aaagctggat
    43741 cagaaacaat cactgcagaa ataccgacat cacgcaaact gcggaaaaat tcccctgctc
    43801 catcttcatt tccttcatgg gtgaccatat tagcagcaac gtataccttc gcatcatgtt
    43861 cttttgcaaa agcaactcct tcagccattt cttcataagt aaaattacct gcacggcttc
    43921 ttaaaccata tgcattcccg ccaatatata ctgcatctgc tccataatgg atcgcggttt
    43981 ttaacttttc cagtgttcct gctggcgcta ggatttctgg tcgtttcaat tttcttttta
    44041 ctgtcatttc tttcatcata ctccttattt gatagcagaa ggatcaatat aaaagaatcc
    44101 tgtatctaat tcacggtttt caggatgcaa tttactgatt tcgctagtca ttttttccgc
    44161 tttttcttga tcccagctac cttctaaaat ttgttttttt gcttcggcga atagtcgagt
    44221 gatgtttacg aatttttcgc ctggagtaaa taatccgtcc aatttccatg tacagtaatg
    44281 atgctgataa agttcattca attcattcga gagattcaga tcattgctgg caaaaatatg
    44341 tgtgccatga ctatcttcat aaatagaata atgtgtctct tcttttttag gttccgagat
    44401 aaaaagacct ctttcacgat ctttttgttc gtcttgtttc gtatagttat agtaattctg
    44461 tagcagtgga cgtttggatt gatggatgca tgtagcacca tacacaaggg tttctacagg
    44521 aatatcgagt ttttcttcca tcgccttcat ctcttcaaaa ggaacttcac gagcaagtac
    44581 tgctccaact gcgccttttt tcgcccagaa attgatttga cgtgcgctcg ttactaatgt
    44641 ttcagcatca taaatatacg gtatacgcaa ttcaggattt tttttcatcg tataaataat
    44701 acctgtatca ccaactgtga tcacatctac gtttatttct tttaaaaaag ccaaatattc
    44761 aggtacattt ttcatttttt caggatgaat gatcccattt acagcaatat tcgctttttt
    44821 accatacttg tgtgctaatt ctaccaattg tcgctgttct tctcgtgtaa atgaagcagg
    44881 cagacgcaat ccaaattgct cttcaccgaa atatagtgta tctgcacctg cagcaagcaa
    44941 ctgttctgct tgttcaatag tttctactgt ggttatgagt tcgatcataa ttttctcctc
    45001 ctacaacttc ataatagtag catagctcta aaaactttcc aatacttctt ctatttaaag
    45061 tcggattttt gaaaattatt tcacaaaaaa tcaaaataaa gttcgatata ttctgtccaa
    45121 atataaaaag agattgtgac aaaaatcttg tcacaacctc ttaatcaagt cttactatta
    45181 taaaaattca gctacacagg ccaagtaact atagggaacc tactgtttcc tttttaggtc
    45241 cgcgaacatt caatgtgatc ttaccttttg aagcacctac tgttacgtgg tcacctaaac
    45301 gaatttctcc gccaagcaaa gcctcgctca atcgatcttc aatttctttt tgaagtgcgc
    45361 gacggattgg acgtgcacca tattcaggat caaatccagc tttcccgatc acatcgattg
    45421 cagatggtgt gattttcact tgaatatctt gttctttcaa tcgtttgata atcgctttgc
    45481 tcatgatttg gacgattgta tggatttcat ctttactcaa tgaatggaag acgacagtct
    45541 catcgattcg attcaagaat tcaggtcgga aagctttctt taactcttct aagatacgtt
    45601 tttgcatggc tttgtgatct ttagtaacat cttggacatt gaatccgaca tttttttctt
    45661 ctcgaatttg tgtcgctccg atatttgaag tcataatcat gattgtattt ctaaagtcca
    45721 cttttctacc tttagaatct gttaaatgac catcatccaa tacttgcaga agtaaattga
    45781 aaacgtctgg atgtgctttc tccacttcat ctaagagaat cactgaatat ggtttttgac
    45841 gaattttttc tgtcaactgt ccaccttcat cataccctac gtatcctgga ggagacccga
    45901 ttaatcggct tgtactgtat ttttccataa attctgacat atcaacacgg atcagggcat
    45961 cttcacttcc aaacatgact tctgaaagtg ctttggccaa ttctgttttt ccgacaccag
    46021 ttggtccaag gaacatgaat gaaccaattg gacgatcagg atctttcaat ccgcttcgtg
    46081 cacggcggat cgcacgtgaa actgctttga cagcctcatc ttgaccaacg acacgttcat
    46141 gcagaagtcc ttccagttct aacaagcgtt cgctttcttt tttctccaac tgctgtagag
    46201 ggacaccagt ccactccgat acaactgtag caacatcttc ttctgttaca cgatcagaat
    46261 aaccttgctc ctgttttgct tcaattgcag aaactttttg cagcttttta cgtagtgctt
    46321 tttcttgtct gcgtaattga gcagcatttt caaagtcttg tttttggatc gctgcttcct
    46381 tttcttgtac tagttcatcg atttctagtt tgatcacagt tgattttgtt aagtgatcgg
    46441 tttgatccaa acggactttc gctgctgatt catcgatcaa atcaattgct ttatcgggta
    46501 gttgacgaga agtgatataa cgaacagaaa gattgactgc tgctcgtaca gcttcatctg
    46561 tgatctccac tccatggtgc tcttcatatc ttgtacgtaa tccttgaaga atcacttctg
    46621 cttcttcagg agttggctca tctacttgaa tgcgagcaaa acgtcgctct aatgcagaat
    46681 ctttttcgat atatttttga tattcatcta gggtcgttgc tccgatcgtt tgtaattctc
    46741 ctcgagctaa cgccggtttc aagatattcg aagcatcaat tgctccttct gctccacctg
    46801 caccaattaa ggtatgcaat tcatcaatga ataagattac ttgaccatca ttatagattt
    46861 cgtcgatgac ctttttcatt cgatcttcaa attcaccgcg atatttcgta ccagcaacca
    46921 aagatcccat atcaagcatc atcaggcgct tttcttgcat gtcttctggc acttcaccta
    46981 aaatgatttt ttgagctaac ccttcagcaa tggctgtttt gcctacacca ggttcaccca
    47041 ccagtacagg gttattcttt gtccgtcggc taagaatctg gataagccgt ttcacttctc
    47101 tcgaacgacc aacaactggg tccagcttgt tttcttttgc taatttcgtc aaatcacgtg
    47161 ctaatgaatc tagcgtaggt gttccttgcg gtgtttgccg tttatcttgt acatttacat
    47221 ttctacgacg attcattcct tttccagcag aatcaccagc tagccccatt ttttgtttca
    47281 gaacttgacg ggcttttgaa aggctgatac ctaagttgat catgattcga gtagccatga
    47341 tactttcatc ttttaataag ctcatcaaaa tatgttctgt tccaactttt tgagaaccag
    47401 ttttcttcac ttcgctgcta gctaaagcaa aaacttgttt cattcttggt gaatatggaa
    47461 gaaagactcc tttagggtaa gaacggatac caccataacc aatcagatgt tcaatttctt
    47521 cataaatttc cgtttcattc aaatccattt cacgtaatac ttttccagca attccatttt
    47581 gctcgaccac taaggctagt aaaacatgtt ctgaactaac tgattgatgt ttcaaccgtt
    47641 ttgcttcttc ttgtgcaatt tctaatactg cttgggctct ttcagtaaaa agttcttcca
    47701 tctaatctca cttcccatct tcataactta aacgttccag aaatgctcgg agaatccgag
    47761 cacgtgtatg atcttcatat tcattgaaat tcaatgtgtt ttttgcaatt gcactcaaca
    47821 tcaagtttcc ttcttttttt gtaattattt ggtcttcata aagtttttga ataatagcaa
    47881 aagcattttt ctcactgatt gtatcatcaa ataactgatt tatctgctca agtaattgtt
    47941 ttttatctga aatccttact tttgcaattc gtatataacc accaccacca cgtttgcttt
    48001 ctactagata accacgttgg atggtaaaac gggtattaat cacatagttg atttgtgaag
    48061 gaacacagtt aaagaggtct gccatttcaa tccttcgaat ctcgatcatt tcactatttt
    48121 ccagaatttt ctttatatat gattcaatta aatccgaggt attctgatgt gccatcttat
    48181 tcattccctt tgactaatat tgaccttaat tataacgaat ttgataatag aaagaaagaa
    48241 gaacgctttt tgttaaataa atcctttaga atcaacaaaa aaaaatacgg aatatactat
    48301 tccgtatcga cgcgcccaag aggagtcgaa cccctaacct tttgatccgt agtcaaacac
    48361 tctatccagt tgagctatgg gcgcatattc aatttaaaaa aattataaat catttgaaaa
    48421 caaaaagcaa gataaaaaaa atcgggaaga caggattcga acctgcgacc ccttggtccc
    48481 aaaccaagtg ctctaccaag ctgagctact tcccgtttaa aaaataaaaa agac
//
LOCUS       DAIGTA010000017        44498 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.017, whole genome shotgun sequence.
ACCESSION   DAIGTA010000017 DAIGTA010000000
VERSION     DAIGTA010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.017"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..415)
                     /locus_tag="NOB43_001001"
     CDS             complement(<1..415)
                     /locus_tag="NOB43_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI0981879.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETYKRLRIDPKDLE"
     gene            complement(400..1011)
                     /gene="mobC"
                     /locus_tag="NOB43_001002"
     CDS             complement(400..1011)
                     /gene="mobC"
                     /locus_tag="NOB43_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HCI0981880.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVALTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(1015..1212)
                     /locus_tag="NOB43_001003"
     CDS             complement(1015..1212)
                     /locus_tag="NOB43_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981881.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(1227..3911)
                     /locus_tag="NOB43_001004"
     CDS             complement(1227..3911)
                     /locus_tag="NOB43_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981882.1"
                     /translation="MKIIGKKIANRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TKSQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAVVDGIQNMIPEVLDLF
                     SFVESAGLNKVYQSVLSTIVVGLMILSLVIVGYKMIIGKGTVDLKSVGMNVVMSISLI
                     LLMPTLIHSGIEFSKTFYNDSTTITDSDEGVAWSLIEQGVTDLAYINKTDQYSMIDKT
                     NDRNNLTKENFWKTDLTQVLTDNVLDKMEKENPIADNLRYELVENSDNEFVATKFSDN
                     FLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRVLGVLV
                     FATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFVNYLNAGEGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRSKGGKN
                     SGGNDQAEGEERKPERNFGQSLSQKANKTGKTLGYARERGLSGLASDGATMASERATK
                     PFKSMRDIANDTKNKFKEGLDDGTVSAINKNSKPIVAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNTNHASAIQQKVKQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEIMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQDRRSVDVRENLQNTTSSQSGNRIVDVRENVQSSASNQSRTVDV
                     RENLQNTTSSQSGNRTVNVRENVLSSGTSQPRTVDVRENLQNTTSSQSGNRTVDVREN
                     VQSSTSSQGFKTVDVRENVQKDSGEMKEKAQKINIVEDRKSAKKFDSNHETVIIDSEI
                     RENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLKK"
     gene            complement(4136..5005)
                     /locus_tag="NOB43_001005"
     CDS             complement(4136..5005)
                     /locus_tag="NOB43_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HCI0981883.1"
                     /translation="MAEKRMLSKTFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYVKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKLDVILKSGQVEPLRVDLMEKWYPVGIPSINHLEVQSSQDQISSDK
                     SSLVKNSIDKINQVDTIINEEIINEKGIQLIHKLGDRFTKSQREKFVQLIVDMKNSTE
                     REFKIRIDGPHYYEQTNKMIIRLFNTINEKLNLGKELNEMKYVNTVSRNHWKEIALEE
                     QDNRMYIIDALSK"
     gene            complement(5159..5461)
                     /locus_tag="NOB43_001006"
     CDS             complement(5159..5461)
                     /locus_tag="NOB43_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0981884.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGESFERK"
     gene            5663..6460
                     /locus_tag="NOB43_001007"
     CDS             5663..6460
                     /locus_tag="NOB43_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0981885.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            6511..7653
                     /locus_tag="NOB43_001008"
     CDS             6511..7653
                     /locus_tag="NOB43_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0981886.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENYSVKMYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(7751..9142)
                     /gene="sufB"
                     /locus_tag="NOB43_001009"
     CDS             complement(7751..9142)
                     /gene="sufB"
                     /locus_tag="NOB43_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCI0981887.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(9147..9617)
                     /locus_tag="NOB43_001010"
     CDS             complement(9147..9617)
                     /locus_tag="NOB43_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HCI0981888.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(9604..10839)
                     /locus_tag="NOB43_001011"
     CDS             complement(9604..10839)
                     /locus_tag="NOB43_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0981889.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(10836..12122)
                     /gene="sufD"
                     /locus_tag="NOB43_001012"
     CDS             complement(10836..12122)
                     /gene="sufD"
                     /locus_tag="NOB43_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCI0981890.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(12135..12908)
                     /gene="sufC"
                     /locus_tag="NOB43_001013"
     CDS             complement(12135..12908)
                     /gene="sufC"
                     /locus_tag="NOB43_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCI0981891.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(13105..13953)
                     /locus_tag="NOB43_001014"
     CDS             complement(13105..13953)
                     /locus_tag="NOB43_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI0981892.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(13977..14663)
                     /locus_tag="NOB43_001015"
     CDS             complement(13977..14663)
                     /locus_tag="NOB43_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0981893.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(14656..15690)
                     /locus_tag="NOB43_001016"
     CDS             complement(14656..15690)
                     /locus_tag="NOB43_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0981894.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(15753..16009)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16085..16423)
                     /locus_tag="NOB43_001017"
     CDS             complement(16085..16423)
                     /locus_tag="NOB43_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HCI0981895.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(16425..16781)
                     /locus_tag="NOB43_001018"
     CDS             complement(16425..16781)
                     /locus_tag="NOB43_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HCI0981896.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(16787..17974)
                     /locus_tag="NOB43_001019"
     CDS             complement(16787..17974)
                     /locus_tag="NOB43_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI0981897.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(18165..19010)
                     /locus_tag="NOB43_001020"
     CDS             complement(18165..19010)
                     /locus_tag="NOB43_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0981898.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            19244..20209
                     /locus_tag="NOB43_001021"
     CDS             19244..20209
                     /locus_tag="NOB43_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HCI0981899.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            20586..21629
                     /locus_tag="NOB43_001022"
     CDS             20586..21629
                     /locus_tag="NOB43_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HCI0981900.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(21691..22155)
                     /locus_tag="NOB43_001023"
     CDS             complement(21691..22155)
                     /locus_tag="NOB43_001023"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCI0981901.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            22401..23348
                     /locus_tag="NOB43_001024"
     CDS             22401..23348
                     /locus_tag="NOB43_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0981902.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(23559..25631)
                     /locus_tag="NOB43_001025"
     CDS             complement(23559..25631)
                     /locus_tag="NOB43_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI0981903.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(25564..25941)
                     /locus_tag="NOB43_001026"
     CDS             complement(25564..25941)
                     /locus_tag="NOB43_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HCI0981904.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(26070..26648)
                     /locus_tag="NOB43_001027"
     CDS             complement(26070..26648)
                     /locus_tag="NOB43_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0981905.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            26780..28072
                     /locus_tag="NOB43_001028"
     CDS             26780..28072
                     /locus_tag="NOB43_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0981906.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(28132..29250)
                     /locus_tag="NOB43_001029"
     CDS             complement(28132..29250)
                     /locus_tag="NOB43_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HCI0981907.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(29264..30685)
                     /gene="arcD"
                     /locus_tag="NOB43_001030"
     CDS             complement(29264..30685)
                     /gene="arcD"
                     /locus_tag="NOB43_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HCI0981908.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(30931..32052)
                     /gene="mnmA"
                     /locus_tag="NOB43_001031"
     CDS             complement(30931..32052)
                     /gene="mnmA"
                     /locus_tag="NOB43_001031"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCI0981909.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            32456..33055
                     /locus_tag="NOB43_001032"
     CDS             32456..33055
                     /locus_tag="NOB43_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HCI0981910.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(33193..34479)
                     /gene="efmA"
                     /locus_tag="NOB43_001033"
     CDS             complement(33193..34479)
                     /gene="efmA"
                     /locus_tag="NOB43_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HCI0981911.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(34750..35094)
                     /locus_tag="NOB43_001034"
     CDS             complement(34750..35094)
                     /locus_tag="NOB43_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HCI0981912.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(35231..36376)
                     /locus_tag="NOB43_001035"
     CDS             complement(35231..36376)
                     /locus_tag="NOB43_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0981913.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(36556..37530)
                     /locus_tag="NOB43_001036"
     CDS             complement(36556..37530)
                     /locus_tag="NOB43_001036"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI0981914.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(37610..38485)
                     /locus_tag="NOB43_001037"
     CDS             complement(37610..38485)
                     /locus_tag="NOB43_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HCI0981915.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            38615..40522
                     /locus_tag="NOB43_001038"
     CDS             38615..40522
                     /locus_tag="NOB43_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HCI0981916.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(41063..44341)
                     /locus_tag="NOB43_001039"
     CDS             complement(41063..44341)
                     /locus_tag="NOB43_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HCI0981917.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT        12557 a         9316 c         7863 g        14762 t
ORIGIN      
        1 gttctaaatc tttagggtca atacgcaacc ttttatatgt ttccatgtta atattattaa
       61 tgacaagatg actatgaaaa tgatctttat cattgtgact tgcaacaatg atttgcgaat
      121 ttggaaaagc tttctctgca aattcgacag ctatttcgtg cattttatca atacttaact
      181 ctttagaagt actcttatca aatgaatgaa taacatgaaa cgcttgtgct atatctttag
      241 atttattcat cttggtacgt actaaattca tttcttgcag tgcttcctca ctatcatcac
      301 tacaatttat tcctgagact gcaacacatt tttctttttt tgaaggatta gctgcatatt
      361 gtaatagcga ggataaattt ttcttgcgtc ctttcgatgt tatagtagct cccaaagttg
      421 tttcacctca tcttttaaac ttgcaataat ctgaattgag tgaattaaat tccgatcaac
      481 tttttgggaa tactcttctt tcgtacccgg tctagtttgc ttttctatcc aatattcgaa
      541 atattctttt tctacttctg ataatttaaa aaaagaggga gcactccgat tggactccaa
      601 aaaaatgtca tctggataac taatcatcaa cttttttgct atgctattcg caagttcatc
      661 tttaaaaatg ttgtaacggc tagcatcaaa actaaaatgt aggctctttt cttttttatc
      721 ttcagattct tctctaaaat atttagcaat gatatttaat gcctttaccg cttgattcaa
      781 attgttacca atttgattta actgtttggt taaagctacc ctatcatctt cagctaacaa
      841 cggcggttca tatttgagtc cctttaaccg ctcacggcaa acgtctgctc tagaaattcc
      901 cctttgtttt gcaatcaatg tcagttcaag ataagtcttt ttatcgacac gaaaatttaa
      961 ggcctcacta tgtttgcgat ttttttcgta cattttttgt ttatcatcca ttgattatcc
     1021 cctcacattt ttttccagag agcaacattt gaaattgctc tctatttcat ttttcatctt
     1081 taattcttct tgaatcatca gttcaatata attagtgacc gtgatttttt catttgttgc
     1141 gttctttact gattcacata attcgtcaag ttctaagaaa tcatgcgtac taatctttag
     1201 aattaattgc atgacaatcc ccccttttat ttttttaata gattatcgaa aagtggatta
     1261 ggatcattaa gtgtatctct gaataactca ttgtcttcat aagtgaatct tcgtcttgat
     1321 tttgatccct tatcattttc acggatttca ctatcaataa tcactgtttc atgatttgaa
     1381 tcaaattttt tcgctgactt tctgtcttca acaatattga ttttttgtgc tttttctttc
     1441 atttctccac tatctttttg aacgttctcc cgaacatcta ctgttttgaa tccttgacta
     1501 cttgtagaac tttgtacatt ttctcgtacg tctactgttc gatttccact ttgactactt
     1561 gtagtatttt gcaagttttc tcgaacatct actgttctcg gttgacttgt cccactactt
     1621 agtacatttt ctcgtacatt tactgttcgg tttccacttt gactacttgt agtattctgc
     1681 aagttttctc gaacatctac cgttctcgat tgatttgacg cactactttg tacattttct
     1741 cgtacatcta ctattcgatt tccactttga ctacttgtag tattctgtaa gttttctcga
     1801 acatctactg agcgtctatc ttgactactt gtagaatttt gtagattttc tttgaccaat
     1861 ttttctaatc cggtatttga atttttagct tcttgaattc tttctttggt caacgcttct
     1921 ttttcgtcca tattagcccc tgtacgccct tctacacgtt tcctcaacat ttcctcacga
     1981 ttcattattt caggcgtgta ttttgcttcc tgtcgcttct gattaattaa ttcttcagca
     2041 gacttagctt gaccgtgcat agcattttta cgttcttcaa tatcttgttt aactttttgc
     2101 tgaattgcac ttgcatgatt agtatttgat tcagcattat ttttcattgc ttcacgcata
     2161 cgttcagaac tagacataat tctatcagcg ttttcaactt tagcgccatc ttttctatcc
     2221 gaaagacgcg ttggcataga atcagcatat tttccagttt catcttcttt atttttagct
     2281 actataggtt tgctattttt attaatagcg gacacggtac catcatctaa accttcttta
     2341 aatttattct tggtatcatt agctatatca cgcatactct taaatggttt tgttgctctt
     2401 tcactagcca ttgtagctcc atccgaagct aagcctgata atccacgttc acgagcatac
     2461 ccaagcgttt tccccgtttt attagctttt tgagaaagtg attgaccaaa gttgcgttca
     2521 ggttttcgtt cttccccttc cgcttgatcg tttccaccac tatttttccc acctttagat
     2581 cggttcatac cacctgttcc tttacgaaac agcatagctc ccataccaaa tgctgaagca
     2641 agctggccat agccttcttt taaaccaata tccacgccaa agtaacgcat gactgttcca
     2701 ctacccttta ttagaacgaa cacggcacag atataagcaa ttgtttttat aaaaatattc
     2761 gttgagatac cttcaccagc gtttagataa ttaacaaaca ttgcaaacat agacaatccg
     2821 aatccctgaa aaccgacagt caaataacac tgtagaatat ctgacaaaac ttgttttgat
     2881 cgttgtcctg tttctaagtc agtagcaaat accaaaactc caagtacgcg tttaaatgct
     2941 aactcgagta ttgctgtaat tataatgaaa gcactaaaaa catacgctac tgctaaagca
     3001 atcaatccaa atgaaattcc ccacaagttc gcttgatagc gataatatcc tgatttgata
     3061 ccatcaacaa aggttgacaa aaaattatct gaaaatttag tagcaacaaa ttcattatca
     3121 gaattttcaa ctaattcata acgcagatta tcagctattg ggttctcttt ttccattttg
     3181 tcgagtacat tatctgtcaa tacttgcgta agatccgttt tccaaaaatt ttcttttgtt
     3241 agattgttcc ggtcattcgt tttatcgatc atggaatatt gatccgtttt attgatataa
     3301 gctaaatcag taaccccttg ttcaatcagc gaccacgcca cgccttcgtc tgaatctgta
     3361 atcgtagttg aatcattata aaaggtttta gaaaactcta ttccgctgtg aatcaaagtt
     3421 ggcattaaaa gaatcaatga aattgacatt acaacattca ttccaacaga ttttagatca
     3481 accgttcctt tacctataat cattttataa ccaacaatca ctagtgaaag tatcattaag
     3541 ccaacaacaa tggtacttaa aactgattga tagactttgt tcaatccagc actttccaca
     3601 aagctaaaca aatctaaaac ctcgggaatc atattttgaa tgccatcgac aacagcgaac
     3661 attgatttta taacagacca gcctatccac ataccgaact gactgtaaaa atttccgtta
     3721 tattttttaa gataattctg ataaagtgga ttagttaaaa actcagtttg gctttttgta
     3781 tcatcaaacc agttgaaaat actgccttct gcaacgttac tcgtaaaaat aatcatagct
     3841 atgagaataa gaaaactaat caacaaccaa tttatttttc tattggcaat cttttttcca
     3901 ataattttca ttgttacctc cctcagccca gtttctgagg ctctcagaga gcttttgagc
     3961 aattttttgg tcaatgatga tatgagttac ataactatca ttcactgctc ttaaatcgag
     4021 aacaatagtg ttgaagcaga tacactcgat taattcaagt gtatctgcgt tttggtcaag
     4081 acagcagatt tgatctatta gacgatttcc aatcatatta agagtccttt cttgtttatt
     4141 tacttagagc atctatgata tacattctgt tatcttgttc ttctaaagca atttctttcc
     4201 agtgatttcg agataccgtg tttacatact tcatttcatt caattcttta cccaagttta
     4261 atttctcgtt aatcgtatta aataatctga ttatcatctt atttgtttgt tcatagtaat
     4321 gtggcccatc gattcgaatt ttgaactctc tttctgttga atttttcata tctactatta
     4381 attgaacgaa tttttctctt tgacttttag taaatctgtc acctagttta tgaatcagct
     4441 gtattccttt ctcgttaatt atctcttcat tgataatagt atcaacttga ttaatcttat
     4501 ctatactatt cttaactaaa ctagatttat ctgaactaat ctgatcttga cttgactgaa
     4561 cctccaaatg gttgatgcta ggtataccaa ctggatacca tttttccatt aaatcgactc
     4621 ttagcggttc tacttggcca gatttcaaaa tcacatcaag ttttattggc tttaattttg
     4681 agaaaaattc tggttttaag ttcaataact tgaagcgata aatagatggt ttatacctat
     4741 ctattcgtat attttggttt tgtaaccaat gcggtaggaa tgctaacaaa tcttcattta
     4801 aaaaaaatac aaaacctttt gtaaaaagta tctttacatc atcgtcagga gtcccgagca
     4861 ttttcacgta tggatatgct tcaacaattc cgtcatcgtc tgcatttgtg ttcagatata
     4921 catataataa ttttgctgaa tctgacatct tcataaaact tgcattattt aaaaatgttt
     4981 tggacagcat tcgtttttct gccatggatt tcacacttct ttctatttga atggtaaaat
     5041 aaattcaaat aaagttttat cagaacttta ttgttgggtg tttcccttcg tctacaaact
     5101 atcgggagca ctcttttata tatttttttc aattcttttc aagtctaaat ttgttatttc
     5161 attttctctc aaaactttca cctcttttca ttcgagcaaa cataaactca ttaactgcct
     5221 ttttcgaata aaattttctt gcccctaatt caacaacggg caatccctca tttctcaccg
     5281 cattttttaa aaagttttcg ctcacattta agtattctgc catttctttt tgatttagat
     5341 attctctagt catacccgca ttttcttgag ccttctcaat cgcttttgta gcaatttgat
     5401 aaaactgctt tagaaacatt tcctcctgtt cttctgaaat cattaatttt attgcttcca
     5461 caaaaacctc tcctttttaa ttaattattc tataactcct ctacctttat aagtacaaat
     5521 aaatacaaat tgcgtaaaaa aatgtattta tttgtattta taagaataaa gtatcatact
     5581 ccagataaaa agtaaatact tttaaatact tttgttttat aaatatgata tactatcttt
     5641 aaaaataaaa aggagaaaaa agatgaagcc aaatccttca gaagcaggaa aacgaatcaa
     5701 acaattacgc ctttcatgtg gttttactat ggaagaactt ggaaggaaaa tagataattc
     5761 accacgtgcg accatatcca actgggaacg tgggaccaat ttaccaaatc cacaaaagct
     5821 gaaattatta tcaactatca ctaattcaac aattgactgg attaaatggg gaactttaga
     5881 agaatatata acttcatacc ttatcgatat agggtatgag ctatatatta aggactttcc
     5941 agaaatacct cacaaagtct ttaaagacat tcaagaaaga tatagtgata cgttttcgct
     6001 agataaagac tatgagttat tgaatcctat aataaaaaat atatttacaa aatattactc
     6061 aaaagatttt gaaatttatc taaatgagat acttgctaat aatatcaatc ctctgattga
     6121 agagtacgct aaccaaagac actctatctc taaagagcta tttttcaaaa gagccaacag
     6181 taaacttcaa gacaagataa gaaatggtga tttcaaatac ggtgaaaaag aaagaatgat
     6241 tgattcttta aaacagctat tagacgaaat ggacttagcc tataaagata tttcaaagta
     6301 ttcatctgtc gaggatttct tttataaaat tactaaaaac caatttgaaa cagaaaaatt
     6361 tatttcagat cttagtaaaa aatacaattt cccatatgag aaaaatagta taatcgcaaa
     6421 atttttaact gataatcacg ataaatttaa aaataattga ttcttcaaat aacttctcta
     6481 cctgcaataa tgaagtaagg agagaatcaa atggcaacat tttttagtta taaattacaa
     6541 aatggcgaaa aatattgggg atttgaaact tatttaggga aagatcccaa gactggaaaa
     6601 gatatacgta caaagcgtag aagattcaaa tcaaaagctg aggcgcaaac agcacttaat
     6661 agactacttg tagactttaa agaaaaacaa gagtttaaaa tcaatgttac aacttttcaa
     6721 gagttgtatg aattatggat tgataactac agaacaagag taaaaccgtc ttctgttgcc
     6781 gttgctcaac gtttttgcaa aaaccatata ttacctgctt ttggggaatt acgattggat
     6841 aaaataagtg ttagctattg ccaaaaacag gtgaatgaat ggcacaaaac attaaaacaa
     6901 tatggtttct tgagaaaaac aactgctcaa atttttaaat ttggagtagc aatggaagtc
     6961 tgtaaggata atcctatgtc taaaacattg cttccaagaa aaattgaaga agaacaaccc
     7021 ttgaagtttt acacgaaaga tcaattacaa ctgtttttac agaatactaa agaaaattat
     7081 tcagttaaaa tgtacacttt tttccgttta ttagcttata caggaatgcg taaaagcgag
     7141 gcattggcgc ttcaatggga agatatagac tatttcaaca aaacaataac aattggtaaa
     7201 actatcgctc aagacgagtt taatcaagta gttttacaag tacctaaaac taaaaattca
     7261 tcaagaacga ttcagcttga tgattttaca cttaaacaac tgcgtatttg gcaacaagaa
     7321 caaatgaaaa taatgatctt atatggctat aacacgaatt caccaaaaca gtttcttttc
     7381 actacaaaca caaacaagtt gtactacccc caagtagtaa acgattggtt agactggatt
     7441 tacaaaaaga caccgatgga gcctcaaatt actccacatg gatttaggca tacccactgt
     7501 agcttattgt ttgaaagtgg tgcgtcgata aaagaagtac aggaacgatt aggtcataaa
     7561 gatattaaaa ctaccatgaa tatctatgct catgtcacac cacaatctgt taagaaaact
     7621 ggtgaccgat ttgcaaaatt tatgggcgaa taattccaaa cgtagccaaa aacgtagcca
     7681 accattaaaa tacaaataaa aaaacgctcg aaacgcttta atatcaacgt ttcgagcaat
     7741 gaaatagttg ttaacccaca gacccttcca tctcataact gatcaatcga ttgagttcga
     7801 ctgcatattc cattggaagt tctttggtga atggttcaac aaagcccatg acgatcattt
     7861 cagttgcttc agattcggtc aggcctcggc tcatcagata gtagagttgt tcttctgaga
     7921 tttttgagac tttggcttcg tgttctaaag agacttggct gttgtggatc tcattgaatg
     7981 ggatcgtatc ggatttcgac cattcgtcca tgatgatcgt gtcacattcg atatgagaga
     8041 tcgaacccgc actgtttttg gcaaaggtta cttgtcctcg atagtttact tctccgccgt
     8101 cttttgaaat tgatttagag acgatagagc tagatgtatt tggtgcattg tggatcattt
     8161 ttgcacccgt atcttggatt tggtttgctc ctgcaaaggc gatggagagc atggtgcctc
     8221 gtgcaccttt tccatctaag taaacacttg ggtatttcat cgttgttttt gcacctaggt
     8281 ttccgtcgat ccattcaacg gttgcgcctt cgtatgcttt tgctcgtttg gttactaagt
     8341 tgtacacatt gtctgaccag ttttggatcg ttgtgtaacg gcaatacgca tcttttcttg
     8401 taaagatttc tacgatggcg gcatgcaggc tgttacttga ataagtaggt gccgtacaac
     8461 cttcgacata gtggatgctt gctccttcgt caacaatgat cagcgtacgt tcgaattgcc
     8521 ccgtgttttc cgcattgatc cggaagtacg tttgtaatgg aacatcgact ttgacgcctt
     8581 ttggcacgta aataaaggtc ccacctgacc atacggctga attcagcgct gctaatttgt
     8641 tgtcggttgg cggtacaagt tttgaaaagt actctttgaa taattcaggg tattctttca
     8701 aagcagagtc agtgtcagta aagacgattc ctaacttttc gaattcatct ttcatattat
     8761 ggtacacgac ttctgattca tattgtgcgg aagcaccggc tagataagct cgttcagctt
     8821 ctggtatacc aatcttttca aatgtatctt tgattttttc tggtacgtct tcccagtcac
     8881 gagcgggttt gtcacttggt ttttggtaat atttgatggc atcgaaatcg atgtctgaaa
     8941 ggtcggggcc ccatgtttgc attggcattt tgttaaatgt ttctagagat ttcagacgga
     9001 attcaagcat ccattctggt tcgcctttga ttcttgacat ctcacggatc acttcttctg
     9061 tcaagccttc tcctgtactg aaaaccggtt cgacatcatc gtgaaacccg aatttatatt
     9121 cttctaattc tggtacgccc atgttctcac tcctcttcct tgtggtaatg atggaaagct
     9181 gcggtaccat cgttttccat tgcttttcct agtgctttcc aggcaagtgt cgcacatttg
     9241 atccgagcgg gaaatttagc tacaccacca agcatagcag catcgcctaa ttggtcggga
     9301 tctttgactt cttttccttg gacaagctgt agaaagtcta cagttaaatg ttctgcttct
     9361 tctattgatt ttccgatgac ggcgtctgtc atcatcgagg cacttgccgt actgatggag
     9421 cagccactgc cgtcaaaggc gatatttttg atgattccgt cttttacatc gacttgcaat
     9481 tcgatcacat ctccacatgt ggggttgttc aattcgatct tgcttgtcga gtcagtcaag
     9541 cttccacgat gatgcggatg ggaagaatga tccaagatca cttgacggta taaattgtct
     9601 aatttagata gtcccatgtt ggaaaaactc ctttgttgcc atgattgctt caactaaacg
     9661 gtcggcgtct tgcgttgtgt tgtagaaata aaagctcgcg cgagcagtcg ctgatacttc
     9721 aaggtacttc aatagcggtt gcgcacaatg atgacctgct ctgacggcta ccccttccat
     9781 gtctaaagct gtcgcgacat catggggatg taacccatcc aaattgaatg caacgactcc
     9841 tgtccgaaaa ttcgggtctt gtggaccata aacagtcaat ccatcaattg cttgtaattt
     9901 tggcaacaca taagcggcta gttcttcttc atatcgatgg atattgtcca taccgagttt
     9961 ttgcaaataa tcgattgcat ggcctaatgc gatagcgccg gcgatatttg gtgtccctgc
    10021 ttcgaatttc caaggtagtt ctttccatgt actgtcgtat aattcgacaa aatcgatcat
    10081 ttcgccacca aattcaacag gttccatttc ttctaaccat tttcgtttac catataaaac
    10141 accaatacct gttggtccgc acattttgtg tccgctgaaa gcaaagaaat cacagtctag
    10201 tgcttggaca tcaatggcca tgtgcggggc agattgagca ccatctacta cgatgacccc
    10261 gccgttttca tggacaagtt cagctaattc ttgaacagga ttgaagacac ctaagacatt
    10321 ggatacatga gcaatggaga cgattttggt tttgtccgta atctttttcg ctgcatcctc
    10381 catatccagg aagccttctt ctgttagttc gatatatttc aagacagcac ctgttcgttt
    10441 tgccaactgc tgccacggga taacattaga atgatgttcc atgtaagaga gcactatctc
    10501 gtctcctgct ttgatatagc ggtcgccgaa ggttctggct acccaattca agcttgtcgt
    10561 cgtaccacga gtaaacagca cttctgctgt ttcttttgca tggatgaacg cccgtacttt
    10621 ttctcttgct tgttcataat catgggtcgc gcgttctgct aacgtatgga caccgcgatg
    10681 aacattggcg ttatcgtgtt cgtaatagta cgctaatgcc tggagtactt gttttggctt
    10741 ttgggtcgtc gctgcattat ccagataaac taaaggttca tcattgacgt cttgaaataa
    10801 gataggaaaa tcattgcgta gctttttagc atcgatcatc cattcaactt cccttcgatt
    10861 acttcgacta attctttccg aacttgttct acagggattg ctgttaagac agaaccgagg
    10921 aatcctcgaa tcactaagcg ctctgcttct tctttatgca atcctctact catcagatag
    10981 tacatttctt ctggatcaac tcgtcctaca ctggcagcat gtccagcagt tacttcgttt
    11041 tcatcgatca aaagaatagg attcgcatca ccacgtgctt tatcagaaag catcaagaca
    11101 cgactttctt gttgggcatc tgcacctttt gcccctttca agatgtggcc gataccatta
    11161 aaggtcaatg ttcctttttc tcggatcact ccgtgttgca aaatatgccc gatcgtatga
    11221 ggggctttat tggttactcg tgtatcgatt ccttggattt gtctgcccga gctgattgcc
    11281 acgattttga cttctgcgtg tgcaccttct cctgctaaat ctgagtcaaa gtcagcgatc
    11341 acatgaccgt cattcatgac accaattgcc cagtcgacag aagcatctcg taaaatgtgc
    11401 ccacggcgat tcatataaga agtaatattt tctcctaatt gatctacggc tgaatatttg
    11461 atttttgaac cagctttagc gatgacttcc acgatgatat tacctgatga ttttgctact
    11521 tgttctttgg ttgtctggaa acgttccaga taagaaaatt cactatgttc atctgccacg
    11581 atcaacacat gcttgaagaa gtgctcatcg gatgcgccat cttgaatgaa taaggactcg
    11641 agtggttcat cgatcacgac atttttaggc acatacagga aaataccgct gttcataaaa
    11701 gctacatgga gtgcagtcaa ttggtcttcg ttcatgttta ctgctttttt catataatat
    11761 tcttggacta gttctggata ttcgatcatt gcagtgaaca agtcggtaaa aatgactcct
    11821 ttttctgcta attccacagg cagttgttca aaaatcgtcc atgaaccttg ttggacaagc
    11881 acaggattgt ctttcattgc atcaaatgcc ggaatcgtgc ctgtttcact gatggtttgt
    11941 gtttctttca catcaaataa cgaccagcga tggaatttca cccgatcgat atgcggcaat
    12001 ggcagttcat ctgctttcgc tagtgcgtct tgacggaagg ttctcatcca atcaggttcg
    12061 cctttactta aagaaaaatc atttaccgcg tcaagataat cgagccagtt tttttctttc
    12121 attcttgctc ccccttacgc ttcttcttct ttatagtcga ttcctaattc tttactgata
    12181 ccagcgtagc cttctgcttc cagacgttta gctaggtcag cattccctgt catgactact
    12241 cggccttcca tcatgatgtg aacgacatca ggtgtgatat agttcaataa tcgttgatag
    12301 tgggtgatga tcaatgcacc gaaattgtct ccgcgcattt catttactcc tttagcaacg
    12361 actttcaaag catcgatatc cagacctgaa tcgatttcgt ctaaaattgc aaatgtaggt
    12421 tctaacatca acaattgcag gatctcattc cgtttctttt ctccgccaga aaaaccttcg
    12481 ttcagataac gttcagccat ttcttctggc atatttagta aagccatttt ttcatctaac
    12541 tttttcaaaa atgccataac agaaattttg tcgttttcat cacgtttcgc attgatcgct
    12601 gcacgcatga attccgcatt cgtgatacct ggtatctcac ttggatattg catagctaaa
    12661 aataagccaa gtcgcgcacg ttcatctact tccaagtcta aaacattttt cccgtcaaac
    12721 aaaatttcgc cttctgttac ttcatagttt ggattgccca tgatagcggc agataaggta
    12781 gattttcctg tgccgttagg tcccatgatg gcatggattt ctccggtttt cattgttagg
    12841 tttacgcctt taaggatttc tttttcctcg atcgacacat gtagattttt tatttctaag
    12901 acagacatgc attatacccc caaattctct ttcgttctca ctcattttag actaattgag
    12961 aatgaagcgc aatgaccttc cttactaaaa tcaaatatct tttatttatt attaaacaat
    13021 tttgatttct aaattagaat aggtataaaa aagatgagaa ataagccatt acagacttat
    13081 ttctcatctt ttttgttcca taccttattt tgcatcagcc tttactggtt taacagagcc
    13141 gccccatttg tctgtgatcc attcttggac ttctttgcgg tgaagcactt caatcagttt
    13201 tttgattttg tcactgtctt catcaccttt acgagtcgca ataatattca cgtaaggaga
    13261 gttgtccttt tcaagcaata cggcatcttc taatggattc aaccctgcgc cgtaagcgaa
    13321 gtttgcgttg attgcaacta ggtcaccttc atcattttgg tacgtagaag ctaaaagtga
    13381 tgggtcgatc gtatggttga acttcaagtt cttagggttt tcttcaatat catcgaatgt
    13441 tgctgtttcc agatctactc catctttgac tttgactaag ccagcatctt gtagaattgt
    13501 gatgatgcgt ccccagtctg attcagaatt tgaagtaatg attgttgcac catcttttaa
    13561 ttcggaaaca tctttgactt ttttagagta caagcccatt ggttcgatgt ggacagcacc
    13621 ggcattgaca aagtcatatc ctttttcttt gatttctttg ttcaaataag gaatatgctg
    13681 gaagtaattg gcatcaatgt cgccttcttc caaagattgg ttcggtaata catagtcatc
    13741 gaatttgacg atttcaagat cgattccttc atctttcaat aatggtttca catgttccaa
    13801 aatctctgcg tgcggtgtcg gtgaagcgcc gactttcaat gtcgtgtcgt ctgctttatt
    13861 tgctgaatct ttgctgtcgc tgttgttacc gcatgctgct aatcctacag tcagcaaaag
    13921 cgctgctgca aatccaaaaa ttttcttttt catatcctac atccccctat atcctattat
    13981 cttttgtctg ttttcttagt taagaaatca ccgattcctt gaacgataaa tacgattagt
    14041 aaaataatta aagtcgcaac gaatgtcact gttagattac cacgctggta gccttcctgc
    14101 caagcaagac ctccaagtcc acctgcgccg atcgcgccgg ccatcgcagt aaatccgatc
    14161 atcgagatcg ttgtaactgt taatccagaa atcaatgcgg gaatactttc aggtatcaag
    14221 accttccaga tgatttccca gtaacttgct cccattgcat ctgctgcttc cagtacacca
    14281 gggctgactt cacgaaaagc aatctctact agacgggcat aaaatggtgc tgcggataaa
    14341 acaagagctg gaatggctgc ttgcgcacct agcatagtgc ctacgattgc tttagtaaat
    14401 ggaatgatca aaaccatcag gatcataaat ggcgttgacc ggaaaatatt actgatgatc
    14461 gatacgattc cataaatgat tcgagcatac ggtttgtttt tgcgtccaat agagtaaagg
    14521 atcaatccca aaactaatcc gatgatcgtc actaagacca ttgagattaa tgtcatatat
    14581 agtgtatcaa ggatagcctg attcatcgtt tccgggttga tttgtttaaa atctagatat
    14641 gtttctgaaa agcttttatc cacgatggat cacctcaatt cctactcctt gttctttgat
    14701 gaacacttct gcttgatcta attctttggt ttcaccagtc atcaagacag tcaatgaacc
    14761 aaaggaacct tctttcactt gtttgatctt tccatacaca acgttgacat cgatgttata
    14821 gcgtcgaatc gcttgggaaa tgactggctc gttggcattt ctttcgctaa aggtcaaagt
    14881 tgccaaacgg ccgcttggat tttctttgat gagttcagct aatagttctg tcgaatcagc
    14941 ttctggttcg atgtcttgtt gtacaaagcg tttggttact tcttttttcg gttgtctgaa
    15001 gacagtcaat acgtctcctt cttctacgac tttccccaac tccatcacag cgactttgtt
    15061 gcagattttg cggatcacat tcatttcatg tgtgatcaag acgatggtca aattcaattt
    15121 cttattgatc gctaacaata agtctaatac ttcttctgtt gtttgcgggt ccaatgcgct
    15181 agtagcctca tcacaaagca ggatctcagg atcatttgcc aatgctcgtg cgataccgac
    15241 gcgttgtttc tgtccgccgg aaagttgtga aggatatgct tgtccgcgtc cttctaaccc
    15301 gactaaacgc aacagttctt ctgcccgttc tttacgtttg ctctttggta cgccagctaa
    15361 ttccagcggc agctggatat tttcaagtac agttcttgac cataacaggt tgaaatgctg
    15421 gaagatcata ccgattttct ttcggaatgt acgtaattct ttgtttttta attttgtaat
    15481 atcttgatcg tttacgatca cttcgccgct cgtgggaagc tcaagtccat tcaggagacg
    15541 gactaatgta ctttttcctg cgccagaata gccgacgatt ccataaatat cccctttttc
    15601 aacgtttagt gaaacgtcat tgacggcttg gatgtttccg tttttcccat tgaatgtctt
    15661 tttgacattc gttagttgga ttaatgacat gccattcaca tctttctctt ataatttttc
    15721 aaacaaaaaa gccttcgccc tcttgcctta agcaaaagga cgaaagcttg aacttccgtg
    15781 ttaccacctt gatttaccgt tacttcgcaa taacagcctc ttccagtact tggacttagc
    15841 ttctttccgt atactgtcgc gctgtaacgg gcactcccgt agtaagtttg cttacgctcg
    15901 cttactctgc tctaagacca tcttccatct cattttcgtt acccattttc agcaaacagg
    15961 gctctcttca aacgtccgtg acatgtactc ttcttttcaa agctttctcg tttcatatag
    16021 gattgcttat gattatagca actggaagaa tcagtgtcaa cttttttcaa gtgattttct
    16081 gattttataa ttcgtcaaat tcttttggat caacatcttt gaaacttaag atccacgcat
    16141 tcatttcatc tgaatcattc aagatattga tatcttcacc gattttatca ttaacagaag
    16201 aaactgtacc cgttagcggg ctggcaaatt cattgaccgc tttttccgct tcaacttcga
    16261 tcagaggttc atcttttttt agcgattgtc ctgcttttgg cagattggca aacgtgatgt
    16321 ctccaagttc ttcttgcgct tcatttgtca aaccaacaca gtattctttt ccattaaata
    16381 agatccaaag gttgtccttt ttcttcaaat gcttgcctgc cattttatat cagttctcct
    16441 tcataaattt tttcattgaa tccaattgca acaagctggt cctctcgtaa gatcagtggt
    16501 cgcttgatca gcataccatc tgtcgataag acttggctcg cttttgaagc cgtaaactcg
    16561 cctacttgat ctttcagtcc aagttcccga tatttcatcc cgcttgtgtt gaacaggcga
    16621 cggattggta cttgactcgt ttctagccaa gtctcaatcg ttgaggcctt cggtacttct
    16681 ttgatcatat caacggtttg ataactaacg ccatgctggt ctaaccacgc tttggctttt
    16741 ttgcatgttg aacatttcgg gtaccagtaa aaggtgtaca attttcttac ctccttgaag
    16801 atcttgcagg tgcttcattt tggtatctca tcgataatat caacccgata ccgatcatgt
    16861 tccctaaaat cgaggatcct ccctgactaa tgaaaggcaa tgggatccct gttaaaggaa
    16921 gtaatccgat atttgctcca atattctcaa agacatggaa cagcagcatc atgatcaaac
    16981 cgcttgcgat ataggcgtaa aattcattat tcgtatcgaa acacacccga atcatacgat
    17041 agattaaaat aaaatacaag aaaatgacga atgcaccacc gataaagccg aagttttcac
    17101 cgataacggt aaaaatcata tcggactcac gaacaggcac atagatattg cttacgttga
    17161 atcctttacc aaacaagcca ccggtaccaa ttgccaaaag tccttgggcc ggctgataac
    17221 tcattcctga cgtatcatgg aaagggtcca gccatgaatc aatacgtgca aactgataag
    17281 atttgaatcc aactttataa agcaagtctc ttccgccttc agtcgtaacc aagaagatcg
    17341 ttcctgctcc aacgactact gccaagatta ctacaggtgc gatgatgcgc caagagattc
    17401 cagacatcag gaaaatcccg ccaaagatcg caagaaagac aagcatcgtt ccaaagtcat
    17461 cttgggccat gatcaatgct aaaaccggta ttgtcacgat caagagcttc ccaatcagcc
    17521 aaaagtccga tttcatcgtc cgttctttta cttgcgtatt atgtttagtt acgatcagtg
    17581 ccatcatcaa gatgtacgca atcttcatca actctgctgg ctggaaagta aacgcaccga
    17641 atcgaaacca gtttttagac cctgttgaag cagctaaatt ctgatcatag aatttgagca
    17701 agagtcccat taccactaac cccaaaccat aaaggtaagg agtcagtttc cagatccatt
    17761 tggaattcaa atgcatgatg acaacgattg ctgccgctcc aactaaatac cagacaactt
    17821 gcatccctac gcctttcaag actgctggat tgttcggatc atggctaagt gctacatata
    17881 atgagagcag accaatcaaa cataacagaa agactggtaa aatcacgcca taatcaatac
    17941 gattatcgtt cgaagctttt aatttttttt ccatgtttca tcccttttct taaaaaccat
    18001 actgctgatt attatagcgg tccagttaga taatggaaag tctttccata gacatttggg
    18061 aaaaattaac tttccgtttg tgcagttgct tgagcaaatg cagtacaaaa gcctactgct
    18121 tatctttagt gtatcataga actttttttg atacatgcaa ttatctacca gctgagattc
    18181 tcctcgctgt gagaagtttc tgtgctttca ttgtatcgaa ggatctcttc ggcaatctct
    18241 agcagctgat cagaaaccag attggttcgt tggatgaaat aaaaatatcg atggaaattc
    18301 aacggagtca ttggcacatt ttctggaaca gagcgcttag acaaaatcga gcgaccgatt
    18361 ccttccttca gcaacgcaac aattacatcg ttacttttca cgatcatctt cttatcttgg
    18421 atattcatct cttcaaaata acgctgcgtg taatgaaaaa caccagagtt tgcttctctt
    18481 acaagccaca atttgctttt tgggtcccca gcgatgacta gctggtcttc catcaaagag
    18541 tatctttgta cgccggaagt ctctaatggc ttttcgataa aaccaaaatc ggattcatgt
    18601 ttcgctactt gttctaatga ttcatgagaa ttcgtgattt cgatctcaaa atgcacttta
    18661 ggaaaccttt tgatcagatg tttcatcaac tgaggcaaaa gatagacagc aaaggtgtgg
    18721 gaagcaacga tccgacatac ttcttcttca ttttgttcat tgagcaattt ttgctgagtt
    18781 tcttcccatt cttctaacaa aaccagtgtc cgttcatata ataagtcggc ttgcttagtt
    18841 ggaagcatct cttttcttcc gttacgttga aaaagatcga tattcaattc ccgctccaac
    18901 tgtttgattt gattcgagac tgctggttga gataaaaaca gtacttctgc tgctctggaa
    18961 aaatttcttg tttcatatac tgctcgaaaa gtcgttaata acttaaacat ggcaccactt
    19021 ccataacttt ttatgataat tactataaaa actatttgat ttaaatatac aaaaaaccat
    19081 ctataataga aatgtacaac aaaacagttg ctgatccaac tagtaactta gatgaagaca
    19141 atcagctgtc tgcttgctcg taatcataca ttcctattca ttttacaatg tattcgttca
    19201 tcttggtact aaaatctatt aaataaaaag gagaatatta tatatgaaga actttttgaa
    19261 aattattccg atcccgatct gcgggttgat ccttgggtta gcttcccttg gaaatctgtt
    19321 taaagactat caccatgttg ctttaggcaa tctaactggc ggtatctcta tgattcttat
    19381 gatattcatt tttgttaaat tgtttatctt attcgaacac acgaaacaaa cgttgcatga
    19441 tccaatcatc gcctccgttt caccaacttt tacgatgtca ctcatggtta tttgtactta
    19501 ttttgtttca tatgaaagta ttgcaccaat tgtcaaattc atttggctgt gcgctgttat
    19561 cttccaagtg atccttgtct tttatttcaa ttatcaccat gttatcaaag ctgatctttc
    19621 aattgaagca atttatccaa gctggtttat catttacgtt ggatttgggg tcatcactgt
    19681 aactgccggg aacttcttcc cacttattgg aaaaattttc ttttggattt cattgatctg
    19741 ctatgcgttc ttattgccga tcatcatcaa acgtgtcttt ttcgtaagaa atatggctca
    19801 tccgacacgt ccgctgatta cgatcgttgc agcacctggt tctctttgcc taacaggtta
    19861 tcttaaaaac tttgctgaac ctaattttta tcttgtcgta gcattgttcg ctttatctca
    19921 agtattgtat ttcgttgtgc tgtctatgct tccacgtttg ttcaagcttc gtttttatcc
    19981 aagctatgca gcctttacat tcccgcttgt tatctctgca acagctatat ttactactgt
    20041 tcattacttc aacagtttag gtatctatag tagcgtattg gatttcttaa aagttgcgga
    20101 atgtctgttt gcaagtgtag ttgtcttcta cgttcttgct cattacgtac gtttcttaat
    20161 taaagaacat agcaaacatg gaaaatttgt ttctaaaaaa atcgcttaat aatcgattca
    20221 ataggttgtg aaaaagctgt tctgcatcaa gtaataagaa cggccaaaca aaaacagctg
    20281 ttcatgtttt tgtactggtt gggcttatta ccgcagatgc aagcttttga acaccgttta
    20341 ccaagaggtc gtaaaagaag tggtcagctt caagaaataa gaaggaattt acgaaaattg
    20401 cttctcaaat ttttgtgaaa tttcggctta tttccgtaga agctacttct ggaacaccgt
    20461 ttattcgaaa caagaggtcg tacaagactt ttgtcacgac ctcttgttct tttgtcaaaa
    20521 tactggttta gtgctactat gttcgagtat gcttttagta tttattgacg aaaggaaccg
    20581 atcaaatgaa atcattgtca catccaataa aatctgtaaa ggattcagcg gtccgcgaaa
    20641 tcttacccgg tttactgctt tcttttgcca tcgctgcctt cagcaggctt cttgctattt
    20701 atctgccaca gttaggtgga gcgactattg ctattttatt gggtatttta ttaggaaata
    20761 ctttttttaa acagcctgtt ctagcaatcg gcacaaaatt tgctgaaagc aaactattag
    20821 aattctctgt ttttttacta ggtgcaactg tcacagctca aacgattgct caaattggtg
    20881 taaaaggaat tgtttttgtg ttactgcaaa tgtcagtcac tatcatcggt gcttacttga
    20941 ttggtaaaaa actgcaattc agcgatactt cttctttgat gatggctgga ggaaacgctg
    21001 tttgtggttc ttctgctatt gcttcaatcg ccccttccat ccatgcgaaa gaggaagaaa
    21061 aaggacagat catcacacta gtcaatctac tgggtactgt gatgatgttg actctccctt
    21121 ttcttggatt acagttgttt ggtggaaatc tcattgaaaa aagtgcactt ttgggtggta
    21181 cactccaatc tgttggtcaa gtagtcgctg gggcaagctt acttgacaat tctgttgtcg
    21241 aattcgccat gctatttaag attctacgta ttatgatgct cgttgttgtt gtctatctgt
    21301 ttgaaaaatt catgcacaag aaacaaccag ctctgtttga aacgccaact gatacgcaga
    21361 aaaaacgaaa attaccgctt ccttggtatg tattagggtt tgtgatcttt tgtttggtca
    21421 acagcttgtt ttctttacct gtagttattg accaatcggc acattttatc agcagctggt
    21481 ttgagatcac tgctttagcg gcaattggtc tgcgtttaga ctttgcaaaa ttcatgaaag
    21541 aaggtacacg cttcttatct tatggattag ctgtcgggct tctccaaaca gtgatggctt
    21601 tactatttat ttggctgatc aaagtttaga atgaacatga aaaaacagtt gtgattctcg
    21661 catggaacaa tgtccgaatc acaactgttt ttaattttgc agatatcctt ctaacaacaa
    21721 caattggcgt ttgatttcaa ccccatctat tgcgtttccc atatatcctg tcagttttcc
    21781 attttgcccg atcactcgat gacaaggaat aacgattggc aatggattgg ttcgatttgc
    21841 ctgcccaatc gctcgcacag ctttcggact atcaacagca acggctactt ctttatacgt
    21901 tcggatttct ccataaggaa tggtcgacaa agctttccag acattttgct gaaaaggcgt
    21961 acctctcttt atagataaag gaacatcaaa ttcttttctt tttcccgcaa aatattcttc
    22021 aaactgttct tgtgtgcgcg ttaaaattcg ctgattcgct gattcgcttt ctgaaattgg
    22081 ctgaaaagat acagcagtca atccggattc atctgcatct aaccataaaa agccgatagg
    22141 tgtgtgtatt ttcattttgt ttgctcctag tcaatagact ggaacttcct cctttttctc
    22201 tatccaaaac tacttgccaa ctaataaaaa ttgttcttaa aagtttgata aaccgaggaa
    22261 acatggtaaa ctaaatacgt tagtttacaa aaagaatacc tgttctttta cgtaaaatca
    22321 aattttaaag gtgttattta aggtttatta aattttgaat gtaaaccata tataaacata
    22381 cgattgaaag gatagaaacg atgaaagtat caattgttgt cccatgtttt aatgaagaaa
    22441 aaactgttcc tctttttttt gatgaggttg aaaaattcaa aggtgcccat gagttcgaat
    22501 atttgtttat tgacgacgga tcaaaagacg gtacgttagc agcaatcaag aagctagcct
    22561 cagcttatcc ttatgtccgc tttgtctcat tttccagaaa ttttgggaaa gaagcggctc
    22621 tgtacgctgg attgcaagct tctacaggag atttagtgac cgtgatggat gttgatctgc
    22681 aagatccgcc cgaactgctt cctgagatga tcaaccggat cactacttct gatatcgatt
    22741 gtgtcggcac ccggcgttcg actcgtgaag gcgagcctgc gatacgcagt ttctttgcga
    22801 aaaaattcta ccagttgatc aataaaatca gcgatacaga aatggtcgat ggcgctcgtg
    22861 atttccgctt gatgactcgt caaatggtgg atgccgtcct agaattaaca gaatacaacc
    22921 gattttcaaa aggattattt agctgggtcg gatttaaaac agaatatatt tcttatgaaa
    22981 accgcgaacg tgtggctggc gaaacatctt ggtccttctg gaaattattc aactactcga
    23041 ttgatggtat cgtgaacttc tcggatgcac cgttaacgat tgcttcattt atcggcgctt
    23101 tgtcttgtgt cggttctggt attgcaattt tgttcattat tttgcgggca ttgttgtttg
    23161 gtgatcctac atcaggatgg ccttccatgg tctcgatctt cctgttcatt ggtggaatcc
    23221 aattgttatg tcttggaatc atcgggaaat atattgggaa aatcttctta gaaacgaaac
    23281 agcgtcctgt ttatatcata agagaaacag aaaaagtgaa gccaaatgaa ttgaagcctc
    23341 accaataata tacgtcaaat gaagtaaaca tttttttaaa tgaaaaagga ctgtgacaaa
    23401 agtcttgtca cagtcctttt ttccgaataa atggtgttcc agaagtagct tcttcggaaa
    23461 taagccgaaa tttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    23521 aagctgacca cttctatcac aacctctttc atatcttatt acttcttcat tgctgctttt
    23581 agtgctgctg ctaatgggct ttcttctggt tcttctgctt gtgcatattt tttcagcaag
    23641 cgtcgttctt catgtttggt cattttcttc ttctgctctt ttttatcaag caatttttct
    23701 gtcgttccat cgtatttaca acggaaataa gcaccgtttt taccttcgat gatttccatt
    23761 ttccggtgac attgcgggca tcgatgatta gagacttttg gatcttttct tctgcggtag
    23821 ttgcaatctg aattggtgca gacatagatt ttgccgtcac gtgtgttttt ctcgcgcaga
    23881 ttggccccac attctgggca tttcttttgg gtaatcgaga aatcttgata ttcttgtttg
    23941 cttgatttga tctcattcac caagcgtttt gtttcttttt cgattccatt caagaaggtt
    24001 cctgcttgtt tctttcctgc agcaatagct tcaaggtctt tttcccagct ttctgtcaaa
    24061 tctggtgtta ctaaagaggg atttaccaat actaataatt gcttaccttt aggagatact
    24121 tgcagtcctt gaggggtacg ttccatcagt tcagatttga ttagtttctc gataatctct
    24181 gcacgcgtag ctggggttcc cagactgtat ttttccattt gaccaagcaa gcttgcttct
    24241 gacaatggtt taggcggtgc agatagttct tttttgatgg cgaaatcggg attgattctc
    24301 attccttttt cccatttgac tgtttccgtc tcagtttcag tttcgccttt ccatcctgct
    24361 tggacgacac gattttgccg aaaaatgaat cgttctttac caaattcaac cgtaactttt
    24421 gtttggctga ctttatgggg ttgagcaaac agtcctaaaa aacgagagac aatcatttga
    24481 tagatttttc gctcttcatt acttaatttt tcataacgtg ctctgttttc agttggcaaa
    24541 agtgcatggt gatcggtcac tttactgtct tggaatactt ttgtctgttg gacgatggct
    24601 ccgtttttca aatactgctt gacctcagga gcaaagtcgc tgactgcttg caatcgttct
    24661 ttcatcgtac ttttcatgtc atttgtcaga tatttgctgt ctgtacgcgg ataagtaacg
    24721 atcttatggg tctcatacaa actttgtaca agacttaatg ttttctttgc agaatagcca
    24781 tagcgttgat tggcttctct ttggatctct gttaaatcat aaggcaatgg cgcagattcc
    24841 gtttttaatt tttcttggac ttctgtgaca gttcctttgc ttgtactgat caattgaaca
    24901 agtttttgtg cttcttcttg tgtttttaaa gcaaattgat ttttttgaag cattttggct
    24961 tgttcttttc cagcttgcaa cgtgatcgtg aaatacgttt gtggacggaa ctgctcgatt
    25021 ttcttttctt ggtctctcac taatgctagt gtcggtgtct gcacacggcc tgctgataaa
    25081 ttatccgcgt acttcacagt taaggctctg gtcacattca atcctaccag ccagtccgct
    25141 tttgcccggg caagagcaga ttcatacaat gcatcatatt ctttcgcagg tcttagttgc
    25201 ttgaatccag ttttgattgc tttatctgtt tgagaagaga tccataaccg cttcactggt
    25261 ttattgaaat gcacatactc taagatccag cgagcaacaa gttccccttc tcttccggca
    25321 tctgtcgcaa tgactgcttc tgagacatct tttcgctgag ccagctgctt gattgctttt
    25381 aattgatgtc ctgttttagg aagtggtttg attcctagtt ttttagggat cattggcaac
    25441 gtgtccattt gccagctctg ccattcctta ttcagatctt ccggcatttt caatcctaat
    25501 aaatgaccaa gggcccaagt aacgatcacc ttgggtcctt cataataatt tttgtgcttt
    25561 tgattagcac caagcacctt gcttaggtct ttcgcaacgc ttggtttttc cgctagaatt
    25621 agttgtttca taaaattcct ttctgctttc tactgtgatg ggctgatgat ttttcaacaa
    25681 cgcaagtccc ttgtattgct gtaaatcatc gtcacactct tcacaccagc gctcatctcc
    25741 gtcattccaa aaggcgctga gaaagttact ttttgcattg atatattcat aattttgatg
    25801 gatttcgttc cattgttttt cgtacgcttg tcgtgcttct tcgaaagact cgaatgtttc
    25861 ttcttcttca atatcttctt cccagtcttc aaaaaaccac caaggctcat tgtccccgaa
    25921 catggtaatt acttgataca tactcgtgct ccttctttca gcttttctag actcatctta
    25981 gtcacttttc aagaaagttg caagaatttt ctcttataaa agggtcattt aatgaacatc
    26041 ttaaaattgt tacaaatgaa tctgattgtt taaggcaaag tagcgataaa gttattgatc
    26101 atccaaaaat agctgtcttc tggatcgatt gttggttctt ttgtaaagta tcctaaaaaa
    26161 cgtaaggaaa gataaccgtg gatcatacta cgaagttccc tgcttcgatg aactttttct
    26221 tctttcgtta attgaaaagc ctcaaatatc tgcaaaatga tctgattcgt ttcatggatt
    26281 ccatctaata aaacagcttc attggtatgc ggtacactga tcagtaactc atacactgct
    26341 tgatttgaaa aagcaaagga tcgataagtt tctgcataga tctgcagtgc ttcctgacca
    26401 ctttttccca caagagcccg tcgcagctgg tcattaagtt cctgcagaag tttcgctgtt
    26461 agcgctgttt tgacatcacg aatatttttg aaatggttat acagcgaggg agccttgata
    26521 tccaagcgtt tggctaaatg ctgaaaggtt atttgctgaa catccatctc ttctgctagt
    26581 tctcgaaagc agtcgatgat tttctcttga gacagatttc tttttttcat ttccatgttt
    26641 cctctcataa aataaatcct tcactctttc agtttaccac gaaaaagaaa gagaaaaaag
    26701 agactttcat tgataaacta catattgtag tttataataa agagctgtag atgaaaattt
    26761 tcagaaagaa ggagtctaat tggctgcaag aataaaggaa aaattattta ggaaaagaga
    26821 aacttgggaa caaaacttgt ttgtcttatg gtttggaaca tttatggctg gtatcggatt
    26881 tagtttagtc atgcctttta tgtcacttta catagatacg ttaggtaatt atagtacgtc
    26941 acaattgaac ttttggagcg gattgacttt ttcatctact ttcttggtga ctacgcttat
    27001 ctctccttgg tggggaaaat tagccgacca aaaaggaaga aaattgatgc tgttgcgtgc
    27061 ttcattagga atggcaatcg tcatttcttt gatgggttgc gtgactagtg tgtatcaatt
    27121 agtcgcattg cgtctgcttc aagggatttt ttctggttat atcagtaatg ccactgccct
    27181 tgtcgcaact gggacgccaa aagaaaaaag tggtcaagtt cttggaacct tagcaactgg
    27241 ttctgttaca ggaacattac ttggaccgct tcttggcggg atctctgctt cagcgtttgg
    27301 ctatcgccct acctttttca ttacagggat catcttattt ttcgtcttct tgttgagtct
    27361 gtttttcgtc catgaaaaat ttgtcccagt gaaaaaagaa aacatggttt ctgccaaaca
    27421 gattttcaaa gacttgaaat atccacacgt cgtcatcggt atgttcgtca caacgatgat
    27481 catccaagca tccaacaatt ccattagtcc aatcatcagt ctgtacattc gccaattgct
    27541 gcatggacat gggaatgtta cgttgatcag cggaatcatt gcttcgatac ctgggattgc
    27601 cactttgata gccgctccaa gatttggtcg cttaggtgac aagattggga gtgaaagaat
    27661 acttgcgatt ggtttgggtt ttgcgattct ggtttatatc ccaatggcat tcgtcacgaa
    27721 tgtttggcaa ttagctgcct tacgtttttt gattggtatc tctgatgctt gtctgctccc
    27781 tgctgtccaa gcattgatca caaaatattc gcctcatcaa gctgctggac ggatcttcag
    27841 ttataaccaa tctttccaag caactggtaa cgtagtaggg cctatgatcg gctccagtgt
    27901 ttccagtgca tttggttatc gcggcgtctt tctttcgact tctcttcttg ttttggtcaa
    27961 cttcttgctt gtacgacaca atacacaaga gatccatcag caagaaactg cagaagaaaa
    28021 agcttcagga gtctccatag cttcagggca ctctccttct catagacaat aagcgtaaat
    28081 gaaaaacact gcttgaacag ttgtcacaga ctgtccttgc agtgtttttg tttaggcctg
    28141 ttttttcaag aactcagata agaggaataa tcccttttcc aaggtttctt ttttacaaca
    28201 gtaacctagt cgggcatgct tcggtaaatc aaaggcactt cctggtacta atagtactcc
    28261 tgtttcttct aataaattga tacaaaatgt ctggtcatct tcttcgatgg ctaatttaat
    28321 gaaagaagta gagacgtaat tgggagcgac aagttcaact ttcggttcat tggctaccca
    28381 ttgttttaaa atcacaaggt tctctgtaat gatctttttg tttcgcgcca atattttttc
    28441 tttattcttc aatgcatgta cagcaagatc atctgacagg actccgccgc aaatcatcgt
    28501 gtagtctcga tactttcgaa aaacttctgc caactcaggt ccagtagctg tccagccaat
    28561 acgaatacct ggaatggagt aggttttgga tagggaattg gttgctatac ctttttcata
    28621 gacatctacg atcgacaaga attcaccttt atccgttaaa ggcgcatata cttcatctat
    28681 caatacatat gcatctactg tacgagcaat ttctgcgatt ttttctaaag ttttccgatc
    28741 tagcaatgtg cctgtaggat tgtttgcact attcaaacag atgatttttg tttcaggttt
    28801 gactaaggct tctagctgtt ctaaatcaaa ctgccaatct tcttcttcct tcaaatgaac
    28861 aaagtcaaca gcggcaccta aagatttggg gatgtcatat aattgctgat aagtaggaag
    28921 catcgaaaca acatggtctc ctgcttccac taacgcgtat agagctaaaa gattagcacc
    28981 agtcgctcca ttcgtttgta agatgttttc cggatcgacg gtttgataaa gagaagcgac
    29041 ttcttgtttg aaaacatctg atccttcgat ccagccatag tccaatggtt cgtttttgcg
    29101 tttttcgaaa aatttactta cgctagtccc atctaagcca acgagttcgt ctaatgtcaa
    29161 tgcttcgatc gagctttgtg caatatcata taccgctttc ttttcccatt tatttagcca
    29221 ttcttctaca ccgaaatttg cgattttcat gtttctttcc cccttatatc ttgatccagc
    29281 ctacagcaag caacccgatt gaaagcagtg cggccacaca aatcagccca atcattactt
    29341 tttcttttcc cgtaatttga tgtttggttt cacgacaagc gatccagtag aagcaaaaac
    29401 caggaagata ggcaatacta cataaaagga cataagaaaa tcctgctaaa atgatgccca
    29461 tcaattcaaa aactacagca atcccaccga tcactacttg ttttttgatt ccttctttta
    29521 aagaaaactg gacttgatag atcccgacaa gtagataaca aatcaaaatt gccgctgtac
    29581 ataaagaata ggcaaattga taggcataat cagtaactaa gaaagtcaat aagaatagat
    29641 tagtcaagat tgcagtaaca actaacgaat aagttggggc atttttttta ttcgtttttc
    29701 cccaaccttt cggcaacaga ccgtctcgag ccatcaacat cgttgtttct gctgggagca
    29761 tcgtccaaga caaccaagaa ccaatgatcg aaataatcaa gccgatattg atcagcgctg
    29821 ctccccaatt tcccacgatt ccttttaaaa tatttgccat agcaggttgt gaaatagttg
    29881 ctaactcttc ttgagataag acgccgtatg gcaagatcga agcaaggata tagataaaca
    29941 ataaacaaag cagaccaatg atcgatgctt gctgggcttc tgaacgtttc ttcgcgcggt
    30001 tggctaaaac acttgcgcct tcgatcccta caaagaccca catcataacc atcaaacaac
    30061 ctttaatctg caaccagatc gttccttgct gccctgttcc attcactaga ttatcagata
    30121 cgttacccca aaaatcagca gtgaatatat tcactttaaa tgcgataaat acaaatatta
    30181 aaaataggaa taatggcact aatttacaga tcgtcacgat tgtattgatg acgctcgctc
    30241 cttcaactcc attgtttact aataaagtca gaccccaaat aaaaatactt gcaaataaaa
    30301 tagaaggaac attttgtcca cctttgaata tcgggaaaaa ttctcccatg gcgctcatca
    30361 gcatcgttgc aaaagcaaca tttcccagcc acgcagacaa ccagtaaccc caaccactga
    30421 tgaagccacc taatttacca aatgaagctt ccgcgtaacc gaaaatacca ccatctagat
    30481 ctggacgctt ttctcctaaa tgattcagcg ataataccaa agctaaaata ccaatcccaa
    30541 cgattatcca tgaaaggatc gctggccctg gagctgcaga actagccaga tcacttgtga
    30601 tcccaaacac accgcttccg attgacgaac tgacaaccag agcaaccagt ccccatttgc
    30661 taatacccgt cgatttcttt tccatttcca tcaccctcac ttataaaatt gaacaaatca
    30721 cttgcaaaag attcccttct attttgcaac tgctcttgct taacaaaaag caactttatt
    30781 catattattg gatattatga actttttaca caagtatttc aagtataaaa tgaataaaaa
    30841 ttaattttat tgcaaaaaaa cagctatgct atccaaaaga aaaggtgttt cttttgttag
    30901 ccatagctgt tttgattcat ttaatatcgc ttaaacgtat tgtaaaactt ttgtttcttg
    30961 atatgcgtgg tcgatcaaac caccacccag acattccatt ccatcataaa atacaactgc
    31021 ttgtccagga gtgattgcac gtacaggttc gtcgaatacg acttctgcac gattatcatc
    31081 caataagcga actgtcacag gaacgtcttg ctgacgataa cggaatttcg ctgtacactt
    31141 gaattctttt ggcattggtt cattcgtcgt aaagtggatt tcacttgcat ccaagcttgt
    31201 ggcatacaat gcaggatgat ggaacccttg ccccacatat aatgtgtttg tcgctagatc
    31261 ttttcctaca acaaaccagg gttcttgcga atctcctccg ccaccgatcc ctagtccttg
    31321 acgttgacca atcgtataat acatcaagcc agcatgttgt cctttgactt caccatcaag
    31381 agtgaccata tttccttttt ttgctggcag atagttgctc aaaaattgtt tgaagttctt
    31441 ttcaccaata aagcagattc ccgttgaatc ttttttctta gcagtcgcaa ggcctgcgcg
    31501 ttcagcaatt gcccgtactt ctgatttttc catgccgcct agagggaaca tcgtttttga
    31561 aagctgttct tgtgataatt ggctaaggaa gtaagtttga tctttattat tgtctactcc
    31621 acgaagcatg tggaccacgc cgttttcatc gcgagtgact tgcgcataat gtccagtagc
    31681 tacataatcg gcgccaagat ccattgcata atccaagaat gctttgaatt tgatttcttt
    31741 gttgcacatc acgtctgggt taggtgtacg tcctgcgcgg tattcggcta ggaaatattc
    31801 aaatacacga tcccaatatt ctttttcaaa attcacagag taataaggaa tcccgatttg
    31861 agcagctact ttcgctacat ccttataatc ttccgtggcc gtgcatacac cgttttcgtc
    31921 cgtgtcatcc caatttttca tgaatattcc gatcacgtcg tatccttgtt cctttaacaa
    31981 aagtgctgtt acagatgagt cgacaccgcc gctcatccct acgacaacgc gtgttttgct
    32041 gttgtctgtc atgatatcac catcatttca attagattct gaaacatcta cgagttgaag
    32101 gtcgcaactt ttcagtattt tacattatac gtcatatttc tgaaaatttc atcccttaat
    32161 tatcaagtcg taaaaatact gttctactgg acctattcag tacacaaaca tgatagtcaa
    32221 ccaaaaaatc actcatcttt tgagcattcg atataaaaaa ttggcatact cataaaaagg
    32281 gccagccttt cggcaataag gaataatttt ataaattgtg aaaaactatt tttcaaaatt
    32341 gcttcttatc gcttaaagct gcacgtctca tttacaacct tttcttttta gatgttatga
    32401 gttgctcaga taagtgattt tgtttactct aagaaaaaag ggaggcaaaa gatacatgaa
    32461 ttactttatc agtgatatgc actttttcca tgaacgctta ttaggaaaaa acgactttgc
    32521 tccgcggctc tttgcaaatg tggatgaaat gaaccaacag ttgatcacta gctggaatgc
    32581 agtaataaaa gaaaccgacc atgtttatca tctaggcgac cttgctatgc atccgcaata
    32641 tgaaaaagca aatgcagaaa ttttggaact ggtcactcaa ctgcaaggaa caatccactt
    32701 gatcaaaggg aaccatgaca gtcgcgcttt tttccgttat ttagaaaaaa atgatcctag
    32761 gcttactgac ggaagtccca aattttattt ttatgatgta ggtgccatcg ttaaattcga
    32821 ccatcaacaa tattacttga ctcattatcc gatgttgctc gggcctaacg acactatccg
    32881 caatcttcat ggacatatcc atcattacag cgtacctatc gagaacgatg tcaatgtagg
    32941 cgtagacgca ccggaaagag aactcttaaa ggaaaaacta ccatttggca ctccgttatc
    33001 tgagcaacaa atcaaagaaa tctatgaagc aaagaggaag tacgataggt cgtgaaaaaa
    33061 ctgccctata tcaagtatta aacaaataaa gataattact catatttttc atttgagtag
    33121 gcttattgcc acaggaacat taggatcaga aatggagttg taacaagact tctgtcacaa
    33181 ctccattcca tactattcgt ctttttgctc atggtgttct tttaccagtt ttttctgtaa
    33241 ttctttatca taatttcggg cagctgacgt taaaaataaa acgattccgc ataataaaat
    33301 cccgattccg gaaaacaaga acattttttc tacccctaaa cgatcagcta atggtcctgc
    33361 aaataataat ccaattggac ctgccaggtt catcaaagag ttgaagttcc ctaagacacg
    33421 acctaaaaca ttcgattcat aactctgctg gatcattgcc atcagcagtg tattgaaata
    33481 tggcgttgca caacctgctc ctgcattcaa gataagaaag tacaagaacc cttgactatc
    33541 gtttggaacc aatccgcttg caccgatcgt caggcccata atgatgtagg ctataataat
    33601 aggtttcatt cggtctttcc atgttcctat aaaactgatc agtgcaccgc ctaagagcat
    33661 tccgactgcg tagactactt ccactgctcc cgcctgtcca acggaaccac caaagtaatc
    33721 tagcgtcatc aatggataca gactgattgc tggcatgaac aacagcatca caaatgcacc
    33781 attgatcgtt atgtaccata accctttatt atccatcaat tgctgcagcc caaattttgc
    33841 atctttaaaa atagtaagcg gaacttccaa tatttcagga gaaacttttg ggatcttcac
    33901 aaaaatcaat aagccgacac caaaaactgc ccccaataca tctaataaaa taaggtaatt
    33961 gacaggaacg actgaaaaca aagccgcacc tagagctggc gcaatgatga aattcgctga
    34021 ttggaccatt cctaactgtc cattcgtcct tgttatgtga gaagatggaa cgattgtcgg
    34081 cataatcgac tggatcgttg gcatttggaa tgtttgtgcg accgaacgca taaacaaaga
    34141 cacaaaaact agccaaatcg ggaaggattc tgaaatcgtt ccgactactg ctaaaataag
    34201 cgcgaaaatc gctacaataa tatccgtgac aatcaaaaga gcttttttat cccagcgatc
    34261 cactagcggt cctacaaatg ggcttagtaa aaccatggga atcattccta gtaaagtagc
    34321 aaaactcaaa attgtcgccg aaccggtttc tcttgtcaaa taccagatga tcgcatattg
    34381 gacgaccata ctagtgattc ctgacaaaaa ctgtcccgat aaaaagaaca aataatttct
    34441 cttccaattc gttaaaacga ccgactgttc attttccata aacatccctc ttttcttttt
    34501 cattttgtat agcgtttgca caacaatcat tatacgggat tcttttttca aaaaatacct
    34561 ttttccctaa ataacaatcg tttcaattta aatttcttta cttagaaaca ataaatcagc
    34621 aaaatattaa aaataacaac atgtgttaaa tttaaaaata aaaaagacaa ctaatttgcg
    34681 tcgtccttac aaagttagtc atctaacaat aggccgtttc aaaactagtt gtctttttat
    34741 atccacagat cattcgactt tttcgaataa cccacggcta atcatcccat ccatcagaaa
    34801 ataaaattta tcttggctca ttttctgttt tggatctttg aaaatattga ctgctttcaa
    34861 tccatttgct gtagtgatcg acattttcaa tgtttgaata tcttttgata cagtgatttt
    34921 taatttgaat ccttctttgc tttgcggcgt ggcatctaat ggtcggatca attgataatt
    34981 gcctccgttt gtttctgtaa atccattatc gcgcaatgta tatctttttg catcaggatg
    35041 caaacgatag ctaattggtg cgcccagtac cgttgctgtt gtttcaaatg ccatgatttt
    35101 cacctcgata aaattagttt ctctttatta taaaagttta tcctgatttt tactaggttt
    35161 ttcagttaag ttccctaaaa aatgaaggcg ttctctcaga catctgttca tataagaatg
    35221 acttcactag ttattttttg acagcacgaa ctaattgatc aaggaaatac tggatgtcgt
    35281 cttcggtatt tcccaaacca aagctgatac ggatggattc ttttagtatc ggtgtatctt
    35341 ctccatacat tgcttctaat acgtgtgaag gctcgatatt tcctgctgta caagctgaac
    35401 cagtagaaat agcgacccca ttaagatcaa gcttcatcag tagcaaatca tttgcttcgc
    35461 caattaagcg aagattcaac acatgaggga gtttattcgt taaatcacca tttacttgat
    35521 aagggatttc gtttgcttct aatgtatcaa gaatcaattg ctggaatcct ttatatttgt
    35581 tgttacgtgc ttcacgttct tcaggtgaca gcagttcaac tgcttttgcc ataccccaga
    35641 tccctgctaa attttctgta cctgcacgcc gcttttcttc ctgctccccg cctaaaagca
    35701 atgcagggat atttactccg tctcgtttat ataagaaacc gacgcctttt ggcccattga
    35761 ttttatgagc agagatactt aataaatcga ttcctaattc ttctggatgg atcgtttggt
    35821 ttccgtacgc ttgtaccgca tctgtatgga aataagctgg atgatccgct aaaagttcac
    35881 cgatttcttt gattggcatc aaatttccga tttcattgtt cccgtacatc acagagacca
    35941 agatcgtatc ttctcgtaac gcttttttga cctcttcgat cgacagattc cctttttcat
    36001 ctacaggcag atatgtaacg tcaaacccct ttgtctctaa atatttcatg gtattaagaa
    36061 cagcaggatg ttcgatagct gtagtgatta gatgtctgcc ttctttttga cgcgagaacg
    36121 ctgtttctaa gatagctgta ttatcccctt ctgttccccc actgttaaag atgatctcgt
    36181 gaggttttgc ttgcagactg tctgcaatga tttgtcttgc tgtttccaat ttttcatgcg
    36241 cgtggcgacc aaatccatgt atgcttgaag gatttccaaa cgtgtcttgc atgattgccg
    36301 tcatcgcttc aattacttgt ggatgcatgg gggtagttgc cgcatgatcc agataaatag
    36361 ttttcacttc attcatccct tccaaattat tgctaggcac attctagcat aaaatagcga
    36421 acaaaccaaa gaagagctca tttttgtcta gaggacgttt catgggcata gaaaaaagga
    36481 gctgtgacaa aagtcttgtc gcagctcctt gaagctgctc acttctgtca caacttcttt
    36541 ccctcttttt tttgtttatt cgaattcttt ttcttccaga cggaataacg gactcatcgg
    36601 tgtattttca tggatgcgtt tgaccgcttc acccattaat tctgaacatg taacgattgt
    36661 taagttttct ggatgacgat tttcttctgt gaaaacagaa tcagtgatac aaatatcttt
    36721 gattggtgca ttgtctaaaa tacttttcgc atgatcggac aataatccat gtgacgcaca
    36781 ggcatatact tcttttgcgc cgttttcttt taatacattt gctgctcgtg caagcgttgc
    36841 tcctgtgttc aagatatcat ctaccatgat acatgtcttt ccttgaacat caccgatcac
    36901 ataaccaccc tcagttgaag catcatctgc atgatctacg atggctaatg tgctgttcaa
    36961 atattctgaa agactacgtg cacgctgaac accgctgttt tttggcgaaa caactacgat
    37021 gtcatctccc gtcagaccta attgacggta ataatgagca aacaacggca tcgtaaataa
    37081 attatctaca ggaatatcaa agaatccttg tacttgaacc gtgtgcagat ctaaagtcag
    37141 tactcgagtt gcccctgctt cttcgatcaa gttagcgatc aatttcgcag tgatcggttc
    37201 atgaggtttc gccgtgcggt cttgcctagc atacccatag taaggcaata cgacattgat
    37261 cgttttcgca cttgctcgct tcattgcatc gatcatgatc agtagttcca tatagtaatc
    37321 attgacaggt gcattcgttg attgaacgat atacacatga tcccctcgaa tactttcttc
    37381 gatattgatg gaaatctcgc catcactaaa ttgcttcacg acgcttttac ctaattctgt
    37441 tccgaacact ttcgcgattt tttcagctaa tggacggttg ccattcaaac taaaaatctt
    37501 caacgtgtca tcctgatact tattactcat gtagtcctcc ccaaaacttc tctattcttc
    37561 gatagtttaa catatttttc caagattttc tgttaatttc agcaaattct taaggaagtg
    37621 aaactgttcc gttactccaa ctggcaggaa tgactttatg ataatcgccc cagttgtcgt
    37681 gtactttgta ataacgttct cctgtttcag tttcaaaata agcgtacgct gtcacccaat
    37741 gattgccata tgtactgcca agtactttca aaataccaat catcacaggt ttgccttcac
    37801 gtatacgttt tgtagctcgc tgccatgaac ctagaagagt tgctcgtgca cgctcatgat
    37861 tgccattctt ctttaaaaaa ctagaaatcc ctgtactaac ctgaaaagga atcgtaggaa
    37921 gtcctagtgg ttggatctgg ctacgcaatg ccttcgtcaa aaccaacgaa tcagccgtat
    37981 ttttcttgcg aatctcattt ggaagcatcc accccttacg atagtcttga taataggcaa
    38041 ggagaactgc tgccgcgtaa gtaccacaaa gatagcctga gggggtagcc catttcttat
    38101 acctcaaaaa acgttcttct ggcaatccca cccagcaatt tgcgagttcc tttcctgacc
    38161 ttttttcttc gatcaaaacg ggaatatctt cttttctgtt gatccatcta gataactcga
    38221 ttggctcttc attgatcagc ttccattttt tacaagaaag accctcttga taagtatatt
    38281 ttgctggaga atattctacc ggatgtcctg attgatcgat aatcacataa ctttgatctt
    38341 caaaaaccag agctaaaaaa agcaatttac tttttcttga ctgcagctgc tgagtgctgg
    38401 ctaatttttt aattttttta tctactttga aatataaagg tttatccact acttgattca
    38461 gttgggatcg cctccttttt ttcattataa gtgaaggatt gaaaaaaaca aatcagtttg
    38521 attgttcgaa ttttcaattt tttatgttct atttgttaat tccttcattt tgtaagataa
    38581 tgggcacacg aaacaaaaaa ggagcgatcg atgaatgaac aaagaacgat tgaaacaaga
    38641 tttctatgaa gcagtcaatg aagaatggca aaaaacagca aaaatccctg cagataaacc
    38701 agctacaggc ggtttccaag atttagttga cgggatcgac caacttttga tgggagaaac
    38761 agacgatctg cttgcccatc cagaaaaagt gtcttcagaa aaaatgaaac atttccttgc
    38821 atattatcaa ctggcaaacg attatgaccg aagaaatgag ttgcatgctc aaccgcttca
    38881 acctataatc gaaaaagttg aatcattgca gtctttcgac gaattgaata agcaatttcc
    38941 agaatggctg ttggatacat taccattgcc atttaatctg gatgtagatg cagatatgaa
    39001 gaatgcgcaa acgaacgcct tctttgctta tccgccttct ttattccttc cagataagac
    39061 gtattatgca tcagaccatc ccaacggtgc acaactaata ggcgttttct ttgatatggc
    39121 tgttcagtta ttagagcttg ccggcaaaga aaaaagtcag gcagaagcaa tcacggaaca
    39181 agcagtgcaa tttgataaat tgattgctcc tcatgtaaaa agtgcagaag aaaacgcaga
    39241 ttacagcaaa atgtataatc cgcaatcttt tgatacattt attaaataca cagataaact
    39301 ggacttgaaa aaacttgtca cgggtttgat tgggacaact ccagataaag tgatcgtaac
    39361 tgatccagtg tacttcgatc atttgaatga catcctgaca gaagctcatt ttccgttatt
    39421 caaaagctgg atgatcatta aaacagtacg ttctcttagt ggttatctat cagaagaatt
    39481 ccgccaagtc agcggaatct attctcgcgt attgtctgga acagacgaag caatgcctca
    39541 gaaaaaagca gcgtattacc ttgcctctgg acaattcgat caagtagttg gcgattacta
    39601 cggaaaaaaa tattttggcg aagctgctaa aaaagacgta gaacaaatgg tgaaaaaaat
    39661 gatcgccgtt tataaaaaac gtctagaaga aaatgactgg cttggggatg caacaaaaga
    39721 aaaagccgtc ataaaattaa ataacttagg tatccaagta ggctaccccg ataagatccc
    39781 agcattattc gaccagttca aaacagtacc tgcagatcag ggtggtactt tgctttcaaa
    39841 tactcttgtt ttcagcaaac tcacattaaa agatcgtttc agcaaatgga acaaaccagt
    39901 ggatcgttca gaatgggaaa tgagtgctga cacggtcaat gcttattatc atccatttcg
    39961 gaatgtgatc gtctttccgg cagcgatcct tcaagcacca ttttacagtc tagaacaatc
    40021 aagctctgct aattatggtg gaatcggagc tgttatcgct catgagattt cccatgcatt
    40081 tgataataac ggcgctttat ttgacgaata tggcaacttg aacaactggt ggacagaaga
    40141 agatcttaca caatttcaaa acaaagcaca agcaatgatc gaagaattcg atggtctgcc
    40201 ttttgctgac ggaaaagtaa acggaaaatt aaccgtttcg gaaaatattg ctgatgcagg
    40261 cggtctaagc tgtgcattgg aagcagcaaa aacggaatca gatctttcta tcgaggaatt
    40321 ctttgtcaat tgggcaacga tttggcgtac aaaagcaaaa aaagaatacc aacaactttt
    40381 actgcaaatc gatgtccatg cccctgctaa actccgagca aacgtgcaac caaaaaacct
    40441 tgacgaattc tatgaaacat ttggtatcac ggaacaagac gctatgtatc tagcgccaga
    40501 aaaaagagtg cgaatctggt aagaggttgt gccagaagtg gtcagcttca agaaataaga
    40561 aggaatttgg gaaaatcgct tctcaaattt ttgtgacatt tcggcttatt tttcgaagaa
    40621 gttacttctg gaataccatg tattagaggt tgtgaaaaag ctgcttagtt tcaagtagta
    40681 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttgactt actaccgaga
    40741 aactggcttt tgaacaccgt ttatcgagag gttgtgaaat cagcgtcctg acctgagtat
    40801 tagagaaaaa aacggaaaaa tagttcctca tattttgccg tttgttgagc taataccgag
    40861 ggtcagctga ttgaacaccg tttagtggag agattgtgaa aaagctgtcc tgcatcaagt
    40921 aataagaaca gccaatcaaa agcagcaagg agaacctcat ctataaaaag atagaaggaa
    40981 gtgagacatc tattggtctc atttccttct atttttactt tcctcagtca attgttttac
    41041 atcataaaag gagaaattcc acttattttt ttcgctgttt catgacataa acaactacac
    41101 cgattaacaa aattcctcca gctaatgcta gcaacgggtt attaaattct cccgtttttg
    41161 ggagtccttg agtgccattt ttttcacttt cttttgctgt cctatccgga tgagaaggtt
    41221 ttccatttgg ttttccattt ggtgattcat ttcctggatt ttctctttct ggtttgtcat
    41281 ttcccggggg cacatcggca gtttctcgca cagtgatcgc tttttgctgg gtaacagatt
    41341 ctgtatgagc agaccatttt tccccatcaa atatttccga acgataagtg acttctagcg
    41401 tatattctcc ttttgaaggt gctgaaaaaa tagcggtatg attagaaaat tgagcacttg
    41461 actgtgtttc aacgatttgg atcttttctg ggaaataacg catatcttca aagacaggcg
    41521 ttccttgatt tggtgtgaaa gttgacacaa aaactgtaaa aggcttcagt tcaatgatat
    41581 ttccttctgc attctccgcc acaccatttg cttcttgtat aataatcgga ttattttgtt
    41641 catttggttt tgtctgattt ggttcttgta cgattgcata ctctggatat tccgaagacg
    41701 gtgaggtttc tccgtcaaaa atagcaccta cagataatgg aagaccatcc actctttcct
    41761 tttctgtttg acgattcccc ggtttaatct gcatcagtcc atgaacatgg atacttccat
    41821 tttcatagcg cgtaacaggc tgctgacctt ctttcgaaca tgtatttaga gactcgatcc
    41881 aatcttttga tatggtatgt ccaagagtat tttctgattg tttctctcgt tcattccaat
    41941 agtagttcaa cgagtggtag atttgatctt cgttttgatt caatgggcgg atctgctctc
    42001 tcatctcaag attctctgtt cggaaagata agataccaga agcatggtag tctgtgtttc
    42061 ctgctgaaga ggtataaaga gccacattat atgaaccgtt attaaaactt gtactgctat
    42121 tgacgataat atctgttccg ctattggaat cgattccttt cgcaagattt tcgaaagaca
    42181 aactattgat caattcatga gggcccgtta aagaagaacc gcccattttg aatccattac
    42241 cgttaccttc tccctcaatt cctggtaccc agccgtttcg ataagcaact gagtttttga
    42301 tgattacttt tccgatcgaa cctgtttcat ttttagcaaa aaggtcccaa ccgtcatctg
    42361 cattatgata cgcgatacaa ccgtcaaata catttccttc tcctattgtc agtttggccg
    42421 caaatccatc ggcatcttca aatcctggat cggcattttc aaaagatgta cagttcttga
    42481 ctaagttatg cgcgggccat gcttcgaaag gatcatttga gctaccgctg atttggattc
    42541 ctgtatttcc attccgataa gcatgaatct cttcgatcaa attatgattt ccagaaatct
    42601 gtaatccttt ttgcatagct gcactatttg taatgtcaaa ccctcgtaaa ccccagtagt
    42661 gactgaacag tgtcatccca tttccagttc ctttaaaatc aagtacagga cgcttgtttt
    42721 ctggattttt ctctgcaatc aactgaatcg ggttttctct tgtcccgtta acgccttttg
    42781 gaatcgtcaa tcctctttcg aaggaataag ttccaggcgc catgacgatt gtctgcccag
    42841 catatgcgta tctcaatgct tgtgtcagag ataatggatt ttgtctgctt ccgtttcctg
    42901 catctgaccc ttctggtgtt acataaactg tcgaatattt aggtttacgg tagtccactg
    42961 tatgaagaat ctcttttgtt tcataactag tcatctctac gtattcttct ggcggatagt
    43021 ttttatctgg cgtaaaactg aaagtaaatt cgttcgttcc ttccatcagt tttgtctgat
    43081 aatcaaattc ccgattcgca gtgatagcca agttttttgc gttcttaagc acctctcctg
    43141 ttgctttatt tttaattgtc aataatccgt cagcatttgc tctaaaggac atagtatgat
    43201 cttggtttcc tgaatgatta ctagaggtca cagtgtaaat cggatcaatc aagcgagtag
    43261 gtctttcttg cccaggagga tctgtcgcag gatctgagta agcaacttcg attccttcta
    43321 ccttgatcgt catattcctt gctgcagcaa atcctgcata aataaccgat tcatctgaag
    43381 cgtataattt ttcccagtca tacatgatgt cagaagccat ttcttctcct gtttcaggat
    43441 cgtaataata tgcctctaaa ccagtattcg tttttttcat ctctacgtcc agtttagtaa
    43501 tcgagttcgt ggccggaaac agattcccat gaccgtttcc gaatatatta taagaacctg
    43561 tttctttttc caagaaccct gctgaagtct ctaaaggtgt tgtttccact gagacactcc
    43621 caggagctgg cgcagcttgc ggatcttcag atgatattcc tgtgattgcc cgtgtcccca
    43681 atccaagtcg catcgtatat ttgctgccgc tcgtgttgac cacttcttgt ctatccgagt
    43741 cccagacata ttcgatccga ctgcctagta tggcaaatga atttgaataa aatgcctgcc
    43801 caaacaaatg attttttggt actgcgtctc ttaccattaa agcaaatcct tcttgggcat
    43861 tcgtataggt ccaagattct atttcgatcg tcgcccgcat cctaaagttg atgtctttgg
    43921 ggattgcttg ataataatag gtcattccat ctgatccgct tgactggaat tttccgccgt
    43981 tattcgtgga agagagccgc acgccgtctt ctaatggttc aatggcatac ctactagcac
    44041 ttgtgctttc tccgaaaaca acccctttcc actcttcatt tgcttcttca gattgctttt
    44101 ttgtcttttc attttctgat tctttcatca taggatcatt tccttcttcc gtatccatat
    44161 cttcactagt tcttggtatt tcctccattg ttgacatccc ttcaatgttc acgtgtgcat
    44221 tttcttcgtt cacagactgt tgttcgttag cagcaacttc aacgacagaa attaaaaccg
    44281 gggtactgag cataaggaga ttcatcatta gcgcactgta ttttatacgt ttttttaaca
    44341 agtgtattcc tcccgtaaca aattagaaag cgtttactta aagtattacc taatttattt
    44401 ttactgtcaa taaaaaacaa aattataata agtgtatttt ataaaaagaa aaaatataac
    44461 ttaagttgtt gataataaag agatttatta acggaaaa
//
LOCUS       DAIGTA010000018        42516 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.018, whole genome shotgun sequence.
ACCESSION   DAIGTA010000018 DAIGTA010000000
VERSION     DAIGTA010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.018"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..595)
                     /locus_tag="NOB43_001040"
     CDS             complement(<1..595)
                     /locus_tag="NOB43_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0981918.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDE"
     gene            788..1819
                     /gene="queA"
                     /locus_tag="NOB43_001041"
     CDS             788..1819
                     /gene="queA"
                     /locus_tag="NOB43_001041"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCI0981919.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            2438..5077
                     /locus_tag="NOB43_001042"
     CDS             2438..5077
                     /locus_tag="NOB43_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0981920.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(5245..5943)
                     /locus_tag="NOB43_001043"
     CDS             complement(5245..5943)
                     /locus_tag="NOB43_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI0981921.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            6161..7306
                     /gene="tgt"
                     /locus_tag="NOB43_001044"
     CDS             6161..7306
                     /gene="tgt"
                     /locus_tag="NOB43_001044"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCI0981922.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            7403..7783
                     /gene="yajC"
                     /locus_tag="NOB43_001045"
     CDS             7403..7783
                     /gene="yajC"
                     /locus_tag="NOB43_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCI0981923.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            8088..10685
                     /gene="adhE"
                     /locus_tag="NOB43_001046"
                     /gene_synonym="adhC"
     CDS             8088..10685
                     /gene="adhE"
                     /locus_tag="NOB43_001046"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCI0981924.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            10914..12020
                     /locus_tag="NOB43_001047"
     CDS             10914..12020
                     /locus_tag="NOB43_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI0981925.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            12037..13061
                     /locus_tag="NOB43_001048"
                     /pseudo
     CDS             12037..13061
                     /locus_tag="NOB43_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            13067..13546
                     /locus_tag="NOB43_001049"
     CDS             13067..13546
                     /locus_tag="NOB43_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCI0981926.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            13562..14341
                     /locus_tag="NOB43_001050"
     CDS             13562..14341
                     /locus_tag="NOB43_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HCI0981927.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYKWVIRF"
     gene            14305..14628
                     /gene="kduI"
                     /locus_tag="NOB43_001051"
                     /pseudo
     CDS             14305..14628
                     /gene="kduI"
                     /locus_tag="NOB43_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            14648..15451
                     /locus_tag="NOB43_001052"
     CDS             14648..15451
                     /locus_tag="NOB43_001052"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HCI0981928.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(15700..16764)
                     /locus_tag="NOB43_001053"
     CDS             complement(15700..16764)
                     /locus_tag="NOB43_001053"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCI0981929.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(16761..17846)
                     /locus_tag="NOB43_001054"
     CDS             complement(16761..17846)
                     /locus_tag="NOB43_001054"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HCI0981930.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(17859..18836)
                     /gene="mvaD"
                     /locus_tag="NOB43_001055"
     CDS             complement(17859..18836)
                     /gene="mvaD"
                     /locus_tag="NOB43_001055"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HCI0981931.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(18829..19773)
                     /gene="mvk"
                     /locus_tag="NOB43_001056"
     CDS             complement(18829..19773)
                     /gene="mvk"
                     /locus_tag="NOB43_001056"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HCI0981932.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            20088..20747
                     /locus_tag="NOB43_001057"
     CDS             20088..20747
                     /locus_tag="NOB43_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0981933.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            20832..21737
                     /locus_tag="NOB43_001058"
     CDS             20832..21737
                     /locus_tag="NOB43_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0981934.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(21739..22371)
                     /locus_tag="NOB43_001059"
     CDS             complement(21739..22371)
                     /locus_tag="NOB43_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI0981935.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    22522..22647
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            22691..23215
                     /gene="infC"
                     /locus_tag="NOB43_001060"
     CDS             22691..23215
                     /gene="infC"
                     /locus_tag="NOB43_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCI0981936.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            23287..23487
                     /gene="rpmI"
                     /locus_tag="NOB43_001061"
     CDS             23287..23487
                     /gene="rpmI"
                     /locus_tag="NOB43_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCI0981937.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            23540..23899
                     /gene="rplT"
                     /locus_tag="NOB43_001062"
     CDS             23540..23899
                     /gene="rplT"
                     /locus_tag="NOB43_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCI0981938.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            24251..25489
                     /locus_tag="NOB43_001063"
     CDS             24251..25489
                     /locus_tag="NOB43_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HCI0981939.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLGISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAES
                     YTYNDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLL
                     PVLGVVLLDLPIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGF
                     LMTLAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFHGPMNLVGSGSA
                     ILAVVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIP
                     TGWIIGAILCLITFLLYGNA"
     gene            25537..27666
                     /locus_tag="NOB43_001064"
     CDS             25537..27666
                     /locus_tag="NOB43_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HCI0981940.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            27641..28330
                     /locus_tag="NOB43_001065"
     CDS             27641..28330
                     /locus_tag="NOB43_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981941.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFVTYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(28738..29424)
                     /locus_tag="NOB43_001066"
     CDS             complement(28738..29424)
                     /locus_tag="NOB43_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0981942.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(29560..29754)
                     /locus_tag="NOB43_001067"
     CDS             complement(29560..29754)
                     /locus_tag="NOB43_001067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981943.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(29804..30244)
                     /locus_tag="NOB43_001068"
     CDS             complement(29804..30244)
                     /locus_tag="NOB43_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HCI0981944.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(30248..31093)
                     /locus_tag="NOB43_001069"
     CDS             complement(30248..31093)
                     /locus_tag="NOB43_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HCI0981945.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLEKQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            31242..32660
                     /gene="pepV"
                     /locus_tag="NOB43_001070"
     CDS             31242..32660
                     /gene="pepV"
                     /locus_tag="NOB43_001070"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HCI0981946.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(32736..33938)
                     /locus_tag="NOB43_001071"
     CDS             complement(32736..33938)
                     /locus_tag="NOB43_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981947.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
     gene            complement(33925..35712)
                     /locus_tag="NOB43_001072"
     CDS             complement(33925..35712)
                     /locus_tag="NOB43_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981948.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            complement(35725..36678)
                     /locus_tag="NOB43_001073"
     CDS             complement(35725..36678)
                     /locus_tag="NOB43_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0981949.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            complement(36863..37213)
                     /locus_tag="NOB43_001074"
     CDS             complement(36863..37213)
                     /locus_tag="NOB43_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI0981950.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            37413..38492
                     /gene="pepA"
                     /locus_tag="NOB43_001075"
     CDS             37413..38492
                     /gene="pepA"
                     /locus_tag="NOB43_001075"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HCI0981951.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            38635..38955
                     /locus_tag="NOB43_001076"
     CDS             38635..38955
                     /locus_tag="NOB43_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI0981952.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTASWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            38977..39441
                     /locus_tag="NOB43_001077"
     CDS             38977..39441
                     /locus_tag="NOB43_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0981953.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            39648..40253
                     /locus_tag="NOB43_001078"
     CDS             39648..40253
                     /locus_tag="NOB43_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HCI0981954.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(40292..41581)
                     /locus_tag="NOB43_001079"
     CDS             complement(40292..41581)
                     /locus_tag="NOB43_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCI0981955.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            42010..42489
                     /gene="rlmH"
                     /locus_tag="NOB43_001080"
     CDS             42010..42489
                     /gene="rlmH"
                     /locus_tag="NOB43_001080"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCI0981956.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
BASE COUNT        13468 a         7880 c         8879 g        12289 t
ORIGIN      
        1 cttcatccat gtcatgggtt acaaatacga tcgtttttcc caaacgctct tgtaaatctt
       61 tgacaaggtc ttgcaaggaa tcacgagtga ttggatcaag cgcaccgaat ggctcgtcca
      121 tcaagatgat atcttgattc gctgcaaggg cacgaacgac tccaatacgc tgctgctgac
      181 caccagataa ttcatgtggg tagcgatcta acatctcacg gggcaattcc acaagatcaa
      241 tcattttttc agctgtttta ttccgttctt cttgactgac tttcaacaat ttttggacaa
      301 gagtgatatt ttcacggatc gtcatgtgag gcatcaatcc aatactttgg ataacatagc
      361 cgatctgacg tcgcaattcc actggatcaa tttcttggat ggattttcca tcaatcaaaa
      421 ttttcccttg tgttggatca gtcattcggt tgatcatccg catcgtcgtc gtttttccgc
      481 ttccgctcgt accgataaaa caaatgaact cacccttttc aaatgaaaga ttgacgtcct
      541 ctacagcgac ttttccacct ttataaattt ttgacacatt ttgaaattca atcatggtgc
      601 cacctctttt tctattttca atgaagaact atctattact agtatgccta aaacaatgaa
      661 aaaatacaaa tagggtagtt tttttattta ggaaaacaaa aaatagaagt gaaaaagtgc
      721 tgattttgcc aacagaacga aaaacatgat agaatgatga agcacatgat agaaagtgag
      781 tgacgatatg ttaacaacag aagattttga ttttgacttg ccggaagaat taatcgcaca
      841 aacaccatta aaagaccgcg atcattctcg tttacttgtt ttggatcgga aaactggaga
      901 gatggaagat aaacatttcc atgaaatcat tgaagagtta cagcctggtg atgcgctagt
      961 tatgaataat acacgagttc tgcctgctcg tttatatgga gaaaaaccag atactggtgc
     1021 gcatttagaa gtccttcttc taacgaatac acaaggagat acgtgggaga cattgatcaa
     1081 acctgcgaaa cgtgccaaag ttgggacaag aatctctttt ggtgatggca gattgcaagc
     1141 agtagtgaaa gaagaattgg aacacggcgg acggatcatt gactttgagt atgaaggaat
     1201 ttttctagag attcttgaat cattgggaga aatgccattg cctccatata tcaaagaacg
     1261 tctggaagac ccagatcgct atcaaactgt ctatgcgaaa gaaaatggtt ctgctgcagc
     1321 gccaacagct ggattgcatt ttacgaaaga attacttgat gagatcgaag caaagggtgt
     1381 tgaattagtc tatctgacac tacatgtagg gttaggtaca ttccgacctg tcagcgtaga
     1441 taaaattgaa gaacaccata tgcatagtga attctaccgt ttgacggaag aagcggctga
     1501 gcgattgaac caagtacgta aaaatggcgg gaaaatcgtg gctgtcggaa caacttcaat
     1561 tcgaacatta gaaacgattg gaacgaaatt taatggagaa atcaaagcag acagcggatg
     1621 gactgatatt ttcattacgc ctggctatga attcaaagtg gtagaagctt tctcaactaa
     1681 tttccatttg ccaaaatcga ctttagtcat gttagttagt gcctttgcag gaagagaatt
     1741 gactttatct gcttaccagc atgcgattga agagcgctat cgtttcttta gttttggaga
     1801 tgcgatgttc gtgaaataag gttatgaaaa gccgctagtt ttgaataaca aaaaagcttt
     1861 acaaagattt tatgacaaag aaaaagccga gctctcgata agctcggctt tcttgtacct
     1921 cggaaggatt caaataaaca gaaatgattg taactttcca tcatacatgc aaagcacggt
     1981 gttgaatttc ttcatgttaa acaaaaattt tgttttcgtt acatcttcaa catttgaaac
     2041 atctcttgtt cctattcaat tttcagacgt ttacgttatt caattgttac gtatcgcatt
     2101 acttcttgtt tcggatactt cgtgatccaa acatccatac gcattcacta tttataggtt
     2161 tgtactctac acgcatgtct gggtgaaacc tgtacttcta acaactttgt ttgcttacac
     2221 tgttctatcg agaaattctt ctgtctattt gatggtatcc tccttcctta catctatata
     2281 atagcatcct ttggtagcgt ttgcaaatat aagcacttta aattttacgc tttcttaaca
     2341 aataatcgat aagcccttta tttgaagtaa ataaaaaaag gatgttatag taaaataagt
     2401 accttttttt gtacgaagat tttaaaggag gaataggatg gaagaataca agcagacaat
     2461 agaagaagta aagaaggtaa cagaagcaga tccagatact gggttgtctt cacaagaagt
     2521 ggatgaacgg cgaaaaaagc agggattgaa taaattcgat gaggcgccga aagaatcgat
     2581 gatcaaaaaa ttctttcgaa gcttgtccga ttttacaacg atcatccttc ttgtagcagc
     2641 ggtgatttcc ttttataccg catttgctac agaacatggg gatttatttg aaggactgct
     2701 gatcatcgct atcgttgtga tcaactcggt attggcgatt gtccaagaag gaaacgcaga
     2761 aaaagcactg gaatccttgc aagatatgaa taaacaaacg gcaactgtca tacgagacgg
     2821 caaagtgacc actgttgagt cagagcaact ggtagtgggt gatattcttg ttttagagtc
     2881 cggtgatgct atttctgccg atgcccgttt gatcgaagca tcacaattac gtgtagaaga
     2941 atcggcgttg actggagaaa gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga
     3001 agatgagtca ttaggtgacc aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg
     3061 tcgtgggaaa gcgatcgtca ctgccattgg catggctaca gaaatgggta agatcgcgga
     3121 tcttttgaac gaaaatacta tgcaaaaaac acctttacag gtccgattga atcagctagg
     3181 caaacgaatc agtatgatcg ctttagcggc tgcggcttta gtatttgtga ttggtgaact
     3241 gcaaggagaa ccactccttg agatgttcat gacttcgatt tccttggctg ttgcagctgt
     3301 accggaaacc ttgactgtta ttgttacgtt gacacttgca tacggtgtgc agaagatggc
     3361 gaggaaacat gcgatcatcc gacagttgcc agcagttgaa acgctaggaa ccgctaatgt
     3421 tatctgctca gacaaaacag gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg
     3481 gagcaaagaa gatgaagtaa cgaatatcga agattcaatg acgaacagcg cgatggaaat
     3541 attgaaaatg gctgcactat gtacagatgt gacggtcgag caagaagatg acgaccttgt
     3601 tatcaaaggt aatccaacag aagtagccat cgtaagggct gttgaagaga attatcatac
     3661 aaaggcagaa ttagaagaaa aatatccacg agtaaacgag cttccttttg attctgaacg
     3721 aaaaatgatg acaacagttc accaaatggg cgaaaaatac atctcaatca ccaaaggagc
     3781 attcgatgtt cttgctccgc gctttagttc aggcgatgta gaacaagcgg cgatcgttaa
     3841 tgatcgcttt ggtaaacggg cactgagagt gattgctgtt ggttatgcta cttatgacga
     3901 agaaccgcaa gatatttctt ctgaagcact ggaaaaagac ttacgtttga ttggtctgat
     3961 cggaatgatc gatccaccac gtccagaaag taaaggagca atcaagcgag cgaaaaaggc
     4021 tggcatcaaa acagtcatga tcactggaga tcatgtggtg actgccagtg ccatagcgaa
     4081 agaattaggt atcttgaatg atccgtcaga agcactttca ggatcagaac tgcatcaatt
     4141 atcagacgaa gaattagatg cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc
     4201 agaagacaag atccggatcg tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac
     4261 tggggatggt gtgaatgatg caccagcgtt gaaagcaagt aacgttgggt gtgccatggg
     4321 gatcacagga acagatgtgg cgcaaagtgc cgcagatatg attttgacgg atgacaactt
     4381 tgcgacgatc gtagacgctg tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc
     4441 tatcaacttt ttgctaagct gtaatatttc ggagatcttt attgttttga ttgcgatgct
     4501 gttaggatgg ggagcaccat ttacagctgt gcaactactg tttgtcaatg tagttgctga
     4561 tggacttcca ggatttgctt taggaagaga gccagcggaa cacggcatca tggatcagcc
     4621 acccattccg aaaaatgaag ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa
     4681 tgcaggggtc ttcaccatcg taaccttgtt tggttattat ttaggtagtt atgtcgatac
     4741 tatcagccca tgggtagacg caagtcagca tgtcggtcaa actgttgcat tcttgatctt
     4801 agcttattca tcgattctgc atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt
     4861 caatttagcg accaataaag ctttggtaga aatggcgtta ctggcattag ctattacaac
     4921 ggctgttgct ttgctgccat ttacgcaaga actattcggc ctagtacaca tcagtttgaa
     4981 tcactggttc ttggtaggga ttttatctat cgtaccaatc gcggtgaatg aactgatcaa
     5041 gttccatcga ttaccggaag cagaagaaga ggaatgatta actgtttcta agttgatttt
     5101 ctttttactg gaactataca aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt
     5161 gctaatgggc tgaatgtttc ttttactgcc tctcgataaa cggtgttctc ctgccacccc
     5221 ctcggtcaca agtcacactc tcttttaaat atcttttggc aattgttcat aaaatgctgc
     5281 ttttgttgca gaaatgtatg ggctgagcca tagataacca ataccagcag ttgctaatgc
     5341 taagatatgc cagccgataa atgaaagatc taaccagaaa agttgtcctt tataaccatc
     5401 catcaatttt cgacttgcag tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg
     5461 gacgatatcg tagtaaataa aatagctttg agaataagaa tagcttttaa tgattccagg
     5521 aataactaat agcaaacccc ataatgttgt aaagatcgag atcagcacag ctaagctgat
     5581 cactccgccg ataaacaaac ctttgaatcc acgaaatgca tctttgaatg gttcgatctg
     5641 atctttttgt ccacgtaaaa tatcaagata agtccaagaa ataccgctca tgaacaaagc
     5701 gctaatgatg ctggaaataa ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt
     5761 cgcttctgag acgctcgctg atccatcata tatggtggtg gcaaacaaga taataggaat
     5821 cataataaga agaatagtag caataccaat caatgtaggg attagattta gtaaaacagc
     5881 ttgtccccaa cgtcctttta gactctcttt tgcttggcgt tttaattctg cagaagattg
     5941 catgattttt ccctcctttt ctttaataac accaatatac catgtatcaa aaaatatttc
     6001 tgtcataatg tttttctttt ttttgttatt cataaaaaaa ggataaaaaa aagaatatta
     6061 aataaagtag aaggaagccg agggaacttg caaaaagcac ttgaaacgat tatgatggtg
     6121 ggagttgtca agatatttta tatagaaagt agggaaatga atgacgcaac ctgccattcg
     6181 ctatcgttta atcaagaaag aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc
     6241 acacggaact ttccccacac caatgttcat gccagtagga acattagcta cagtaaaaac
     6301 aatgtcccca gaagagttga aagaaatggg tgctggcgtt attttaagta atacatatca
     6361 tttatggcta cgccctggtg aagacttagt agaagaagct ggcggactgc ataaatttat
     6421 gaactgggat caaccgattt taacagattc aggcggcttt caagtttttt cattaagtga
     6481 tatgcggaat atcgaagaag aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat
     6541 gtttttatca ccagaaaaag caatcaacat ccaaaataaa ttgggctctg atatcatgat
     6601 gagttttgac gaatgtccac cattcgatga aagttacgac tacgtgaaaa aatcagtaga
     6661 acgtacgtct cgatgggcag aacgaggatt gaaagctcat gctaatccag accgtcaagg
     6721 attatttgga atcatccaag gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga
     6781 tctagtcggg atggatttcc ctggttactc aatcggcggg ttatctgtcg gggaacctaa
     6841 atcagaaatg aatcgtgtat tagaattcac tacaccgttg atccccgaaa acaaaccacg
     6901 ttacttgatg ggtgtcggtg ctgctgattc attgatcgat ggtgttatcc gtggagtaga
     6961 catgtttgac tgtgtcttgc ctactcgaat cgctcgaaat ggcacatgta tgacttctca
     7021 aggccgtcta gtagtgaaaa atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa
     7081 atgtgattgt tatacatgta aaaactatac acgtgcctat atccgccatt tgatcaaatg
     7141 tgatgaaaca tttgggattc gtttgacttc ttaccacaat ttatacttct tgttgaatct
     7201 aatgaaacaa gtacgtcaag caatcatgga tgataatttg cttgaattta gagaagcctt
     7261 ttttgaagaa tacgggttca ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta
     7321 aaaattaagt aaaaaactag tgttatcagc atttttctgc taaagtgttt tttgtagata
     7381 cagaattagt gaggtgaaaa aaatgggaac attaccaatg cttgtgatgt ttatcgcgct
     7441 attagcaatg tggtttttta tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa
     7501 cttgttagat agcatgaaac caggtgattc agtcgtaacg atcggcggat tacatggagt
     7561 tgtttcagaa atcgacaatg acaaacggac agttgtttta gactgcgaag ggatcttcct
     7621 tgagtacgat cgtgcagcaa tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc
     7681 aacgactact gttgaaacaa cagaagaacc agctgagaca gttgaagtaa aaactgaaac
     7741 aacagaaacg ctggaagaga cagaagagaa ggaagaaaaa taagtatcaa agcttattta
     7801 aagacgaggt agggcagaaa gatgtcctac ctcatttttt attcaaaaaa gaaagagata
     7861 agagcatggg atatattgct caatattgaa taatcgggtg tgtcatataa ataataataa
     7921 ataactttat atatttttct atacaaacac ctgtaaataa agcaatttta tatttaaaaa
     7981 taactgtgaa aaaaatcaca aaaaagtgtt tacatagaaa aataaatatt gtatgatata
     8041 catgtgaatt atttaacaaa taaccatgac ccattaggag gataatgatg gctaaagtaa
     8101 tagaaaaaga aaaaacgaag acaattgacg tacaagcaat gattgatgat ttggcagaaa
     8161 aagcaaatgc agcattgaaa gaaatggaaa gctttgatca agaaaaagta gaccatatcg
     8221 tgcatgaaat ggcaatggca gctttggatc aacatatgcc attagcgaag atggctgtag
     8281 aggaaacagg ccgcggtgtt tacgaagata aagcaatcaa aaatatgtat gcgtccgaat
     8341 atatttggca taatatcaaa catgataaaa cagttggtgt gatcaatgaa gatgtccaaa
     8401 aagggttgat tgaaattgct gaaccagtcg gtgtggtttg cggagtaact ccaacaacga
     8461 atccgacttc cacaacgatt ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg
     8521 tttttgcttt ccatccaagt gcccaaaaat cttctgcaga agcagcacga gtggtacgtg
     8581 atgctgctat cgctgccgga gctcctgaaa attgtatcca atggatcgaa catccttcga
     8641 tcgaagcgac ttctatgcta atgaaccatc caggtatcgc gatcgtctta gcgacaggtg
     8701 gagctggaat ggtcaagtct gcttactcta caggaaaacc agctttaggt gtaggtccag
     8761 gtaacgtacc agcttatatt gaaaaaacag caaaaattaa acgtgcagtg aacgatttga
     8821 tcgtttcgaa aacatttgat aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg
     8881 ataaagaaat ctatgcagca gtaaaagcag aattccaagc acaccaagtt tatatcgtaa
     8941 aaccagatga attgcaaaaa ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca
     9001 atccatcaat cgttggacat tctgcgatgg aaatcgcaaa attggcagga atcagtgtac
     9061 caaaaggaac gaaaatgctg attgctgaat tggaaggcgt aggcccagat tatccgctat
     9121 caagagaaaa actttctcca gttcttgcca tgatcaaagc taacaacacg gaccatgcgt
     9181 ttgatttgtg tgaaggtatg ttgaatcttg gaggattagg acatacagca gttatccatt
     9241 cagaaaacga agagttgcat gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag
     9301 tgaatacacc atctgcagaa ggcggcatcg gtgatatcta taacgaaatg attccgtcat
     9361 tgactttggg atgcggttct tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa
     9421 acttaatcaa tgtcaaaact gtagcgaaac ggagaaataa catgcaatgg ttcaaattac
     9481 cgccaaaaat cttctttgaa aagaactctc tattgtactt agagaaaatg gaaaacgttg
     9541 aacgtgtcat gatcgtttgt gaccctggta tggtccaatt cggttactgc gatacagttc
     9601 gtgaagtatt ggcacgacgt aaaaatgatg tgaagatcga agtcttctca gatgttgaac
     9661 cgaacccatc gacaaatacc gtatacgcag gaacgaaact gatggcagac ttcaagccag
     9721 atacagtaat cgctcttgga ggcggttctg caatggacgc agctaaggga atgtggatgt
     9781 tctatgaaca cccagacaca tctttctttg gtgcaaaaca aaaattcttg gatatccgta
     9841 aacggacata taagatcgac aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat
     9901 cagggactgg ttctgaagta acgccatttg cggtcatcac tgacagtgaa acacatgtga
     9961 aatatccgtt agcagattat gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg
    10021 tcatgtcagt tccagcatct gtcacagcag ataccgggat ggatgtgtta acacatgcaa
    10081 tcgaatccta tgtttcagtc atggcttcag attatacacg tggattgagc ctacaagcaa
    10141 tcaagttagt ctttgactat ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg
    10201 aaaaaatgca caacgcttct acaatggctg gtatggcgtt tgctaacgca ttcctaggta
    10261 tttgtcactc agtcgcacat aaaatcggcg gggaatacgg gatccctcat ggacggacaa
    10321 atgcgattct tttaccgcat attatccgct ataatgcaaa agatccacaa aaacatgcga
    10381 tgttccctaa atatgactat ttccgtgcag atacagatta cgcagatatc gcaaaattct
    10441 taggtctgaa aggcgaaaca acagaggaat tagtcgaagc tttagcaacg gctgtttatg
    10501 aattaggaaa atctgtcggc atcaacatga gtctaaaagc tcaaggagtc acacaagaaa
    10561 cactagatac aaccgtagac cgtatggctg aattagctta cgaagaccaa tgtacgacag
    10621 ctaatccgaa agaaccattg atctctgaat tgaaacagat catcattgat gcttacaacg
    10681 gataagcaaa agaaagcgta gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa
    10741 cgttgtttct ccaagttctt tttttaattt ccaagtaact gaaagttact tttgttattt
    10801 aacatttagg tcaattttag acagtttttg ttcaaaaagc gatatttata gtggacggta
    10861 ttactgctat attaaggata taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta
    10921 ttaaagaaga gatttttgta cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg
    10981 aaaacctgac aacgatcaaa gacgataatg gtgaattttt gttggacttt gatggactga
    11041 aagtagatga caaaagctgg acagtgtgga attggccaca aggtgtcggt ctatatggta
    11101 tttataaaaa ttaccagatg acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt
    11161 ttgaggatcg tatggaagaa ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat
    11221 tgactatggc ttacttgtat gaagacacga aagattcacg ctatttgcct tatttagaac
    11281 aatgggcaga atgggtcatg aatgacatgc ctcggacaaa tgaagacggg ttacagcatg
    11341 ccacatatgg accggaaaat aagaatcagt tgtgggacga tacattgatg atgacagtgc
    11401 ttcctttggc aaaaatcggg aaactgttga atcgcccaga atatttagaa gaagctcgtt
    11461 accagtttat gatccatatc aaatacttga tggataaacg aacaggattg tggtatcacg
    11521 gctggacgtt tgaaggaaat cataactatg ccgaagcatt ttgggctcgt ggaaactgct
    11581 ggttgacgat tgctattcca gagatcattg aaatcttaga attatcgaaa gaagatgcat
    11641 tgcgcaaatt attgatcgaa acacttgaag cacaagtgcg tgcattaaaa acttatcagt
    11701 ctgaaagcgg tttatggcat acgttgttgg atgatccttc ttcttacgta gaatcttctg
    11761 caactgcagg atttgcttac ggtattttga aagcggtcca taaacgttat ttaccacaag
    11821 aatataaaga agtcgcttat cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag
    11881 gagaagttca aaacgtttca atcgggacag gaatggggga cagtttagat ttttatcgga
    11941 atatcggaat cacagcaatg ccttatggac agtcgttaac ggtgctttgt ttgacagaat
    12001 tgctcgtctc ttattgttaa aagaaaggaa acccatatga aaaaaacatc actgctgttt
    12061 gcagcaagtt cgcttagcct aggtctgcta ggtctaagcg gctgcggaaa taattctagt
    12121 gtggcaactg tcgcagatgc agacgtaaat gagatagtta ccttgcgctt tgcttatgca
    12181 agcaacagcc agtaattgat gcaatgaatg aatttgggcg tttagtaaaa gaaaaaacag
    12241 atggttccgt acagatccag tatttcccag atggacaact gggtggagac cgtgaactga
    12301 tcgaattgac acagtcagga gcagtagatt tcacaaaagt aagtgcctca gcgttggaaa
    12361 gtttctctaa agattattcg attttttccg ttccttatct attcaatgat gaagaacatt
    12421 tctttaaggt gatggataat gaagaaataa tggagccaat ctaccaatcg accaaaaatt
    12481 taggatttac cggattgacc tattatgatt ctggtcagcg cagcttttat atggtagacg
    12541 gtccgatcca tacgccggaa gatttgaagg gaaagaagat ccgtgtgatg caaagcgaaa
    12601 ccgctatcaa aatggtagag cttttaggcg gttcgcccgt acctatggga agtgatgaag
    12661 tgtacacgtc tcttcaatcc aatttgatca acggatcaga aaacaatgaa tttgtcttgt
    12721 atacagctgg acatggcggg gtagctaaat actattccta tgatgagcat acacgtgtgc
    12781 cagatatcat catcatgaat gatgccatca aagaacagct aactgatgaa caggaaaaag
    12841 ccattgaaga agcagcgaaa gaatcaacgg tttttgaaat tgaagctttt gcaaaagcaa
    12901 ttgaagaaga aaaagcttta gcacaagaag aacatggagt ccaattcaat gatgtagata
    12961 atacaccgtt tcgagaggca gttgacccac ttcatgatat attcaaaaac gatcctacct
    13021 acaaagacct ttatcaaaag atccaagagc aaggagcgta gctgtaatga aaatgatttt
    13081 aaacaaggta ttagagatcc tgggagctgt tttgcttgtt gggatggtcg ctgttgtttt
    13141 atggcaagta ttttccagaa cggttttagg aaatccaaat acggtcacgg aagagcttgt
    13201 tcgattcggt cttgtctggt ttgccatgtt gtcttccgcg tatgttgtgg gacaaaaagc
    13261 acatttagcc gtaacggttt taagtgaaaa attaactggc aaaaaaagta aaattttaga
    13321 agttgttgtt caaagtttat ttctggtatt tgctgcgatg atcatggtgt atggcggatg
    13381 gaatgctgtc acattgacaa tggggcagat ctcgccttct ttaagtattc ctatgggata
    13441 tgtttatctg tcagtacctg tatcgggggt actcatcatt atctatagcc tgatcaatct
    13501 aatcgataca ttaagcaaca agccagcaat tcaagaaaaa atataaaaat ggaggaataa
    13561 aatggcaata gaagccggat tagtgttatt ttttgtattt gttgtgttgc ttgtattagg
    13621 gatgccgatt gctataagta ttgcattctc atcgatgatg actttattgt tagttatacc
    13681 gtttgatgtt tctgctttta gttcagctca aaaaatggtg ggaagtatca atagtttttc
    13741 gctgatcgct attccgtttt tcgttctctc gggcattatc atgaataatg gagggatagc
    13801 taagaaacta gtggattttg cgatgttgtt cgtcgggcgc gtgccggggg ctttggctca
    13861 tacgaatgtg ttagggaatg ctttatttgg ttccatctct agctcggcca ttgccgcttc
    13921 taccgcgatt ggtggagtgt tgatccctca gcaagtggaa gaaggatatg accggaagtt
    13981 tgcgacagcg gtcaatatcg cgtcagctcc gacaggtatg gtcattcctc caagtactgc
    14041 ttttatcatg tattcacttg ttgctggtgg tgcttcgatc tctgctttgt ttatgggagg
    14101 ttatctcgta ggcgctttgt gggcgctagg aatcatgcta gtagcattca tcgttgctaa
    14161 aaagaataaa taccctgttg tcgaaaaagg acagatggct catgctggaa aaataataaa
    14221 agaggcgatt cctagccttc tattgattgt catcattatc ggtggtatct tgacggggat
    14281 atttacagca gtagaagctt cagcgatagc tgtcatttac aaatgggtta tacgatttta
    14341 gaaccaggaa gtgcttggaa tacgatgcct tgtcatacac atgaacgtcg tatggaagct
    14401 tatgtctatt ttgattatgc caatgaagat acacgtgtgt tccatatgat gggcaaacca
    14461 gatgaaacaa aacatttagt cgtagacaat gaacaagcca ttatttcgcc aagctggtcg
    14521 atccattcag gtgtaggtac aagcaattac tcattcatct gggcaatgtg cggagaaaat
    14581 atcacctata cagacatgga tatggtgcaa atggatcaat taaaataagc ataagggaga
    14641 gaaaatgatg gaatttagta tggatatgtt tcgtttagat ggaaaagtag cattagtcac
    14701 cggtgctgtc tatggtattg gatttgagat tgcacgctct ttagctacag caggagcaaa
    14761 aatcgtattt aataacttga atcaagaatc agttgatgaa ggtatagcgc attataaaga
    14821 agcaggcatc gatgcaaaag gttatgtctg cgatgtgacc gatgaagaag cggttcaagc
    14881 gatggttcaa cagatcaaag aagatgtagg ttcagttgat attctagtca acaatgcagg
    14941 gatcatcaaa cggacaccga tgatcgaaat ggatgcggca gacttccgcc aagtaatcga
    15001 cgtggattta aatgccccat tcatcgtttc aaaagcagtt attccggata tgatcgaaaa
    15061 aggcggcggt aaaatcatca atatctgctc catgatgagt gaattaggac gcgaaacggt
    15121 cagtgcttat gctgcggcaa aaggcggatt aaaaatgctg acgaaaaaca tcgcttctga
    15181 atacggtcaa tacaatatcc aatgtaatgg aattggacca ggttatattg ctacaccgca
    15241 aactgctcca ttacgcgaaa cacaagaaaa cggtgaacgt catccattcg atcaatttat
    15301 cgttggacgt acgccagcag cacgctgggg cgagccaatc gatttggctg gaccatctgt
    15361 cttcttggct tctagcgcat ctgatttcgt taacggccat gtcttgtatg tggacggagg
    15421 catacttgcc tatatcggaa aacaacctta aaagagcttt agtacaccgt ttagtggaga
    15481 ggttgtgaaa tcagcggctt gaacgaatac cgaaggacag ctgattaaac atcatttatt
    15541 cgaaaaaaga ggctgggaca gaagcgttta actccaagaa ataagaagga attcacgaaa
    15601 attgcttttc aaatttttgt gaatttcagc ttatttccga aggagttgct tttgcttccg
    15661 ccgtttatac gtgtttagag cgtgggataa aagtgttctt tacttttgtc ccacgctctt
    15721 ttctgtgcgt cttccatact tcactaagtc gatccctctt gcttcgcacc aatccttcac
    15781 tggtccggaa aagatcagtg attgttggtg tagggccgcg gtattcgttg cgccgaccat
    15841 agtataaagc agacgaagct cttcttgcca ttgcttcatc agtataatag tttcttctac
    15901 gccgtgattc atcagatgcg tcagtacggt tcctgaagta cccactgcat ttgcgccgag
    15961 acaaagggct ttaaatatgt cataggcatt gcggatacct ccggaggcta ggatttccat
    16021 agaagtgtct gcttcatttg cttcaagcaa tgaagagact gtcgattgcc cccagtcagc
    16081 taaataactc agttcccgct tggagcgacg ggcgttttcg atctgggtga agcttgttcc
    16141 gcttcgaccg ctgatatcaa ctgtatgaac tcctaaagca gctagatcat tgagcgtttc
    16201 tcttgtcatg ccaaaaccga cttcttttac gatgaggggg acgtcaatgg ctgtttgagt
    16261 ctcttgaata agtactttcc aattggtaaa atcacggtct ccctcaggca taaccaactc
    16321 ttgaggtgca ttcaaatgaa tctgtaaggc atctgcgtga aacaatcgga tagcttcttg
    16381 ggctctttcg acagaagtcc ctgcaccgat gttggcaatg attttcccgt gaggatattc
    16441 ttgtcgcata atcgtataag tatcggctaa agaagggtct ttcaaggcag cgctgactga
    16501 accagtggca atcatcaaat ctgcttctct tgcgacgatt gcaagatctt ggttgatttt
    16561 ttttgttttt tcgcttccgc cagtcatcgc attgatataa aatgggctgc ttagtgtaaa
    16621 cccaactgcc tgtgtactta gatcgacatc agaaactgct atttgcggca aagggttatg
    16681 gatgatccgt acgaagtcaa attcgttttt ttgtttatca tgaaaggctt tagctagtga
    16741 aacatgttcg tcttttcgat tcatcggttt tcctttcttt gatcgctata gacatgtaac
    16801 ggcagtggag tgatttctgc tttttcccat gcactcatta aaggaaggat gccagatttc
    16861 tggtcaacaa ttacgattcc gcaatcgcca ccacctgcac cagaagattt tgcggctcct
    16921 tcatactgtt cagctaaatt acacaatttg ttcaaagcag gcgtttcgat gacgacccca
    16981 gtgattgcag ataaatcatg cagtaattgt cggttttttc gaatcatctg ttggatcaac
    17041 gttacattat tttctttaaa ccctttgatc atttcgttga cacattctgt actgtttttt
    17101 aagaaaagct gataagccac cattttgtct tctctcgaac ggtgaacttg atcgaccaaa
    17161 tcagaagtag aggcagggct acccgtccaa ccaatcaata aacgtaaatc ttcaggagca
    17221 atcaatggct caatggatag acctggccaa tccagggcaa gtaactcact gatagaatgc
    17281 tgagtttctt gttcttggag ccaaggatgg tcgaaggttg agaaagcgat ccagccacca
    17341 taacagctag cagcgatgtc gccgcaggaa ccattatctt gaactgctaa attggctagt
    17401 gctgcaatct tgaaaatctc caactgagat aaattcaacg cgtaaaaaac attcaaggct
    17461 ttgaccgttg caacggtcac ggcaccgcta gaacccaatc catatttccg gccatttgaa
    17521 ctgtctaact cacttgttac tttcagatca taaaaggata aaagaatgtt tttttcttgt
    17581 gcatactttt cagtcaaacg aatagcagca aggatataat gaaaaggatt ttcccgaata
    17641 tctaaaacta attctccgtt gcgtcttgtc caacgtacag gcatcccact atattgtgca
    17701 gattggatac ttccgacttt tcgtgcggat tctacagtga ctgttacgaa ttgatcgact
    17761 gcagcgataa ctgctggatg tcctgtttca acaactgcat attctccggc aatatagagt
    17821 ttgcctggtg cagatacttc aatcataaaa atctcccttt attcaataat cgcaattcct
    17881 ggaccagcat gggcagtaat tacttgttct ttgctaaata atttggtaaa tgtttcttgt
    17941 acctcagata aatggctgtt ttccactaaa actttgacat tagggccagc atccatcgta
    18001 aagtagcatg gaatgccttt ttttctcaat tgccgcaccg catccatcgc ttttaagctg
    18061 tcaggagacc agtaagtgaa tggaggctgg gcagctaaag tcgttccatg catttttagt
    18121 ccgtttcttt ccatcgtttc tccgagaagt tggaaatctt ttgttttgat tgcttgtttc
    18181 aattgatata gatccccttc aacggaatct aaccagcctt gataaaaact ggatgtttcg
    18241 actgtccgac gcatcccatt tctgctggac acttcttttt tctggtcgtt gatcaaaacg
    18301 aaaaccattg ctaaatcgtc ttcgaaagaa tcggaaggga ctggcttagc gtaagaactt
    18361 aagtcgtcat ggcctttttc ccattcgacg aaaccaccga aaatacttcg gcaagctgaa
    18421 ccagacccgc gtcgagcaaa tcttgaaaga gagagatcgt ctaatccaag cttaagagca
    18481 gtattgcaag ctcctgctaa agcagctagc ccgctggcag aggaggctaa tccagctgcg
    18541 gtaggaacga aattctgact gattactgaa gcttttagtg agaggccggc ttctttacga
    18601 aaaaggtcaa gaaactgact gacttttttt gttgcttttt cgtcttgtaa ggtgccatct
    18661 agataaaatt catctaccat atagctatca gaaaagatga cttctgtctc tgtataaaat
    18721 gcatccaatg ttaacgaaag gctgttgttc attggaagga tgagttcttc atttttctta
    18781 ccccaatatt tgattagagc aatgttggta tatgcgcgtg ctttgccttt aaacataggt
    18841 atgtactcct aatccttgta tccaagtttc agcagcaccc gcatcttcaa gtgcttgact
    18901 gatttcttgg gcttttgttt ttgtttgtgc taatgcaatc atacagccac cgcgtccacc
    18961 gccagttaat ttggcaccca atgccccggt atcttttgct gtttggatca atagattaag
    19021 aaaatcattg ctgattgtca gcttttccag aagtgactgt gattcatcca ttgtctgtgc
    19081 caacgtttct ggtgaattct caatgattgc ttgttttgct tgcttcgtca agtatcctaa
    19141 tttttggatc atttgtccag tttcatgagg ctgggtttca aagaggtgag cgacatcttt
    19201 gacggcttct cttgtttgtc ctttgattcc tgtatcagcg acaatcaaaa aagcatcgat
    19261 gttcaaagaa aagtagtcaa aaggatgccc ttttgtaaaa taaatcggct gcaagctgct
    19321 agtagcggct gcatcgattc cactaggatt accgtgggcg attttttccg aaagctggac
    19381 attttctaat agtatttcac gagacaaagg aaatgctaag taatcataaa aagcacgagt
    19441 gactgctgtg gcgactgcag cgcttgatcc cattccacgt tcagcaggaa tcgtgctttc
    19501 aatggtcagt tgcaagtttt tttggatgtc atgctgtttt tttaagtgaa tgaataattt
    19561 tttgatattt tttaatgcat gaggagcttc ggctaaattt cctgaatagt aggaagaaac
    19621 cagttgatcg tccattgcat ccagctcttc aaggaatgcg gtgacttttg ttgcatagaa
    19681 aggaaaggca atcgctggtt ctccataaac aaccgcgtgc tcgcccatca atatgatctt
    19741 tccgcttgat tctccttggc catagtttgc cataatctaa ctccttctca cgtaaaagtg
    19801 atttttaagc aaaaaataaa gcgcccaaaa cgagttgcgc tgcttcacga atttttttgt
    19861 ccactaaggg tctcaaaaaa cattcctcct ttattttact aaaaccatct cagaagtaaa
    19921 actaagaata cgttttctaa agaaaaaaca cttttttctt aagaattttt tgacttttgt
    19981 tcttctttga ctagaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    20041 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    20101 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    20161 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    20221 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    20281 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    20341 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    20401 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    20461 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttagagcgt atcgaaaaac
    20521 gtggtcgttc gtatgaacaa ttgtcctttg acccaagtct atacgattat tacaaagaat
    20581 tgaacagacg ttatgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    20641 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    20701 tcgaagaaaa attagcagag attcgccaaa ccaaagtatc catttgattt acagttgctc
    20761 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    20821 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    20881 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    20941 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    21001 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    21061 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    21121 ataccgagta cgtgattcga ctaattcgat cgcttttgga acggatgcca gacatgagtg
    21181 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    21241 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    21301 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    21361 aacaaaatgt agtactttta gaacaaatca aggcactggc tatttatcgc aagttgtcag
    21421 aaaaggaaaa agaagagttg gacgatgcac tgatcgaagc acgacaagca gttgaaatga
    21481 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    21541 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    21601 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    21661 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    21721 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    21781 tgcttgctct tgattgacga ttagtcccgc caaagaatct tgagataaag cgattgttgt
    21841 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    21901 taactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    21961 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    22021 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    22081 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    22141 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaac ctgttttttg
    22201 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    22261 ttggttacct ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    22321 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    22381 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagc ctgctaatct
    22441 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    22501 tgctatacta taatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    22561 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    22621 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    22681 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    22741 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    22801 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    22861 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    22921 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    22981 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    23041 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    23101 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    23161 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    23221 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    23281 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    23341 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    23401 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    23461 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    23521 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    23581 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    23641 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    23701 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    23761 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    23821 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    23881 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    23941 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    24001 aagtctaaaa taacataatt aaggtttttt aattgaaaac tgaacattta tggtcatcct
    24061 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    24121 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    24181 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    24241 ttttgtcatc atggctactg tatggatggg attagcgcta gtcggaaaca cgttttcacc
    24301 aaactcggcg atggaagggc aaggagtaat tgatgtgttg acgcatatct atacgacggg
    24361 gccagctgag tacgccaaat cgatcttggt aaatgtcttc tttggtgcct ttttcgggcg
    24421 tgttctagta gatagcggaa tcgcagctac cctgattcga aaggtagttg aacttggagg
    24481 ggacaagcca agaatcacga tgagcttact atgtattgta accgctgtta tattcatgtc
    24541 gatgacagga atcggaccag tgatttctat tgcagttatt gtgttgccga tcttgatgtc
    24601 attaggtatt tcagtaccgg ttgcactgtt ctcatttatg ggctcgatta tggctggaat
    24661 ctttgctaat atcgtcaatt tcaaacaata tcaaacgatt tatgctggtt tcaatccagc
    24721 ggctgaaagc tatacttata atgactattt ccaaattggt atgattggga tgattgtaag
    24781 cttagttgtg gtactaacgg tcgctaatat atcaatgaac aaaaagaaac gctatgcaat
    24841 ggcagcaaac gtaccagctg aaggtggcga cgcaccaatg atctcatggt tagccgtatt
    24901 attaccagtt ttaggggtcg ttcttttaga tcttccaatc atcttaggtt ttattctagc
    24961 aggtatctgg gcattgctgt ttactggaaa attgcgcgga ggttataaag aaatctgtcg
    25021 tcagtttgcg aaattattta cagatggcgc agtcgatgtt gcaccaatgg ttggtttctt
    25081 gatgacctta gcgatgttca ataattcagc tgcgtatgct tctccttatt tttcagctat
    25141 ttttggagat tggataccgc aatcaccatt agtcttggca atcgtatttg ctatattgac
    25201 accactagga tttttccacg gtccaatgaa tctagtcggt tcaggctcag ctattttagc
    25261 tgtcgtgtta gctgttaatc caacgatgtc gccagccttt ttgttcccgt tatttgcaat
    25321 tacaacgatt gctcctcagc atttagatat tacacaatct tgggttgctt ggggattagg
    25381 ttatacaaaa gtaacttctc gagaatatat gaagaaatcc atcccaactg gttggatcat
    25441 cggtgcgatc ttatgcctga tcacgttctt attgtacggg aacgcctagt aaacaaaacg
    25501 tcgataaaaa cgattagata aatggaggaa aagaaaatga aacgttttgt gcgaatggga
    25561 attgatgttg gcggtacaca tacgaaagca gtcgcaatcg ataatgcgac gcacgaaatc
    25621 atcggaaaat cttcagtgaa aacaacccac gatgatgtcc gtggagtagc cgcaggtgtc
    25681 gttcagtctt ttcaaaattg tttgcgggaa aataatatca gtccagaaga tgttgtgttt
    25741 gttgcacatt ctaccacaca agcgactaat gcactgattg aaggagacgt agcaaaagtc
    25801 ggcgtaatcg ggatggcaaa aggtggatta gaaggttttt tagcaaaacg acaaactaga
    25861 ttgaacgata tcgatttagg gaataagaaa aaaatagaga ttgtcaatgc attcttacct
    25921 gtcaaaaact taaatgtaga ccgtgtttca gaaacgattt cttctttaga aagagaaaga
    25981 gcagaggtct tggtttcttc tatggcattt ggagtagata atggggaacc agaacgagtt
    26041 gtttatgaag cagcatctgt gaaagcgatc cctacaacga tggcttctga catcacaaaa
    26101 ttatatggat tgacaagaag aactcggaca gcagcaatca acgcatctat tttaccaaaa
    26161 atgctagata cggcaacctc gacagaagac tccgtacgag aagcaggggt caatgtttct
    26221 ttgatgatta tgcgcggaga cggcggagta atggaaatca atgaaatgaa aaaacgacct
    26281 gttttaacca tgctttccgg tcctgctgca tcagtcatgg gctctttgat gtacttgaga
    26341 gcgtctaatg gtgtttattt tgaagtaggc ggaacaacaa ccaatatcgg ggtcattaaa
    26401 aatggacgtc cagcaatcga ttattcaatt gtaggtggcc acccaacata tatctcttca
    26461 ttagatgttc gggttctagg tgtggcaggc ggttcgatgg tacgggctaa tcagtcagga
    26521 atcatcgatg tcggtccacg ttctgcacat attgccggtc tagattatgc agtatttacg
    26581 gagacagaaa aaatcaaagg tcctaaggtt gaatttttct ctcctaaaga aggagaccct
    26641 gctgattacg tcaaggtagt gatggaagac ggagaagaag tgactattac aaatacatgt
    26701 gcagccaatg ttcttggatt agtgcaagaa gaacattttt cttatggaaa tgtcccatct
    26761 gcacgaaaag ccatacaggc attagcagac tattgtcata cgacggttga agacatcgca
    26821 gagcagatca tggaaaaatc ctatgctaag attgaaccgg tgattttaga attggcagac
    26881 aagtatcact tggagaaaga tcagatttct cttgtaggtg tagggggcgg cgctgcctca
    26941 ttgattactt actttagtaa taaaatgggt gtgaaatatt cgattcctga aaacgccgaa
    27001 gtgatttctt ctattggtgt agcacttgca atggtccgag atgttgtaga acgtatcatc
    27061 ccttcgccaa gtaaagaaga tatacgatcg ttgaaaaatg aagcgatgaa taaagcgatt
    27121 gaatcaggcg ctacaccaga atcgatcgaa gtacacgtag aaatcgatcc acagacttca
    27181 aaagtaacgg ctatcgctac tggttctacg gaagtgaaag caaccgatct aaccaaggag
    27241 atcacaacag aagaagcact agagcttgct gcagaggata tgcgattaaa taaaaatgaa
    27301 gtttgcttat tggaaaatac acctttcttt tatgtatgcg gcgaacagaa tcgttcaaaa
    27361 aatgctggaa gtcttcggat catcgatcaa aaaggattta tcaaggtcca acgtggacat
    27421 gcttcatgta tgaaaacaac tgcagccaat tatatgacag ctgtcgaaca actttgggaa
    27481 gatatggcag tttatcaaac tgaattgatt gcccgaccag aattttatct ctgcttagga
    27541 gcaagagtct ctgattttac agcgacggat ctggaacaac tacagctttt gatggatctg
    27601 gaagtatcta ctatggaacc ggaggaagaa gtgatcgtcg ttgccggaaa tatcaaacaa
    27661 acataagtta gaagagttac taaacgaatt acaacagatc cccgaagaaa tttggggatt
    27721 ctaccagttt cggcgagatt tattttggaa aaagattcct ttgtccaagc agaaaattct
    27781 tatacaacaa tcaatcgatt gtggtatcga aacggcatgt agcatcaaaa aaaagtaccc
    27841 ttttgccgat gtaggagaaa tctgtgaaca aatggctgtt ccaatcgttt cctgtgaatc
    27901 agagcaaata aacgaacgaa tcacttttgt aacttatgca gaagatgaag ggatccgatt
    27961 gatgacggag ccgttagaaa aattaaaatg ttcaggacta gcttcgatct ctaaagaaac
    28021 agcgcaagct ttgattattg gacatgaact atttcaccac atcgaagctt ctgttaaggg
    28081 aatttatacg caaagcgaaa aaattgtgct gtggcggttg cctttttata cacatcaatc
    28141 aaacattcgt gcattgagcg agatagcagc gatgagtttt tcaaaagaga tgaatcaaag
    28201 cgatttttcg ccttatgtat tagaggcagt cttactttgg ccatataatg aaattcgtag
    28261 ccaagggatc ttagaagaaa taaaagaaat agaaaaaaga tgtacggagt atgatttaga
    28321 ttacaaataa agagactgtg acaaaagtcg tgtcacagtc ctttttttcc gaataaacgg
    28381 tgttctcctg tcaactcctc ggtcacaagt caaaatattc aacaaacatg agaagctgtt
    28441 ttttgaaatt gttccttgtg actcggagat gaacggcagg ctcacgacct cttggaaaaa
    28501 ggtgttcaaa agcttgcatc tgcggtaata agaacagcca agttaaaaac ataagaagct
    28561 atttttactt ggctgttctt attacttgat gcagggcagc tttttcacaa cctctcaata
    28621 aacggtgtgc aatcagctga ccctcggtat tagctcaaaa aaaacggcaa aatatgagga
    28681 actattttgc cgtttatttc tctaatactc aggtcaaaac gctgattcca aaacctctta
    28741 tttgatgggt ctgtcctgaa tatcttcaaa ataatcgggg taattatgaa tcacgtattc
    28801 ttgctcctcg ataatcatat gtaaatgcat cgtgcaaaga aatccgactt catcaaagtt
    28861 atgatcaatc attgattgaa gcattgtctg atgttcatct aatactcgac cccagtctaa
    28921 ttctgaaatc gtcaaacgta accatctgaa acggttcaag tgcgtactat aactttctag
    28981 ccaatcccaa atttctcgtt ttccagcaat ttcataacaa gttcggtgaa aatcagtatc
    29041 caaatcaaaa aaagcttttt tattttgagc gatcactgcc tgatcggttt gttctagtat
    29101 tttttctagt ttagcttgat cttgcttggt cattttcgca ctgcattctt gcaggatcgg
    29161 tttttccaac ttttcccgcg tataacgggc taatgaagca gatcggatat cgatttttga
    29221 aacataagtg ccggactgtg gaatggtttt tacaagctct tgattgcgca gttggatcag
    29281 tgcttctcga atcggtgtac gcccgatagc tagttgttct tctaacactt tatcggagat
    29341 tttacttcca ggtgctaact cggaataaat gatttgttta cgtatagatt cataagcttg
    29401 ctgttgcaaa ttattgataa ccatttaacc ttcctttcta tgcagatata atctattata
    29461 acataaatcg cttacaaatc gtgtgggcat aaaaacacag tctgcaaaaa aagccctgat
    29521 aggcatgcct attagagcct cgaaaagaaa aatattgaat caatctggtc gtacctcttg
    29581 gatcggtttg acacgaccgc cgattctttt agcaaaagct tcggattctt ttttgtcttt
    29641 gaaaatgagc agattgtcta agtttttttc ccgagtgcga cagccagttt tatcgatgta
    29701 accgtgcatt actttaacga catacatggg gatcacctgc ttttttcttt tcattatacg
    29761 aactactcga cacaatacaa gaaaaatgct tagacggtct ttattaagaa tttacatcat
    29821 ccaaagaagc gtacgcttgg aataactgtt ctaactccgg attgactttg ctcagcttca
    29881 ctaatcgttg cgaatcagaa agtaaaaaac agtgtttact actgccagta gtttttaatt
    29941 ttttgtcttc agttcccaca atttcgtagc taaaatccaa ccgtgttccc gtatactttt
    30001 ggatagttgg gtggatgctc actttttctc cgtaatggat catttcttta tagctgcaat
    30061 ttacttccag aacggggatg atgatcccag attcttcgat ttttttatag ggaaacccta
    30121 gatgtaccaa taaggctacc cgagcctctt caaaccagcg gatataattg ctgtgatgaa
    30181 taatccccat ttgatctgtt tcataataaa aaggttctcg cacataacct gtaaatttct
    30241 ccatgactca tgcctcgttt tccattgatt ttttacaaaa ataattcatc cacttcggaa
    30301 gtgcttcgct gatttgtgtc ggcaaaacaa tatattgttc ttttgccagc tggtctccaa
    30361 tgaaactatg aagataaaca gctgctgcaa tcgtttggtc attttgagga aactgggcta
    30421 aaaatcctgt gatcatccca gctaaagtgt cacccatgcc gcctgttgcc atagcagcag
    30481 aacctaaagg attggtgtag aagtgctggt gaccataaat ttttgtctca tgacttttca
    30541 aaacgagcac agcaccgatt tcctgttgct tctttttgtt ttctttatcc cgttgttctt
    30601 gtatcggtag agaactcaac cgttgccact ccatttgatg aggtgtaagt acagtttgtt
    30661 cgggataggg tagcaaaaga tgattagcaa caagtaaact taaagcagag ccatcaatca
    30721 ccagccattg ttcttttgat tgtttttcta gtacttgttt gaaacgttcc aaactcttag
    30781 aagaagtacc caatccggga ccaatcaaga gtacatctgc ttgctttatt acggaaagaa
    30841 actggtcagt atccgtccaa tctacaatca ttgcttctgg cagatgactg tgaagagcac
    30901 tccgattttt ttcatcagtt actacagtcg tgagacccgc tccactgtgt acggcagcta
    30961 aagcactcat aatgattgct ccgccatatt gttcattgcc gccaatcaaa acgatacgtc
    31021 caaatgttcc tttatgtgaa atttttggac gaggtgtgat gactcttttc actagttgtt
    31081 cgtttatcag catcgaaaaa cctcctttta ctcattatag cgtatatttt ttttagagaa
    31141 aaacagataa gaaaaggaat tgtcagattt tttgaactat ttttttctgt aatttgtggt
    31201 atcatgaaca cgaagactta aataagtgga ggattaactt tatgacaatt gattggcaaa
    31261 aagaagtaga agcacgtaaa gaagacttgc ttgaagactt gaaaaatctt ttacgtgtca
    31321 acagcgagcg cgatgattca aaagtaacac cagatgcacc atttggacct ggacctcgcg
    31381 acgcattgaa acatatgtta gcttatggcg aacgtgatgg atttaaagta aaaaatgtcg
    31441 ataactatgc agggcatatt gatcttggcg aaggagacga aacgctaggg atatttggac
    31501 acatggatgt cgttcctgca ggagatggct gggacacaga tccttatgaa ccagtaatca
    31561 aggatggaaa gatctttgca cgcggatcaa gcgatgacaa aggtccaagt atggcagctt
    31621 actatgcgat gaagatcatt aaagaacttg acttgaaact atcaaaaaaa gttcgcttcg
    31681 tagtcggcag cgatgaagaa agcggctggg gcgatatggc ttattatttc gaacatgaag
    31741 aagaaccaga ttttggtttc tcaccagatg ctgaattccc aatcatcaat ggtgaaaaag
    31801 gaaatgtttc tttagcttta cgcttcaaag gcgacaatgc aggagattat gtcttgaaat
    31861 cttttgtttc cggacttcgc gaaaatatgg tgccaggaac agcaactgca gcacttcaag
    31921 taccaagtgc agatgcagct atcgcgatgg aagaagcatt ttaccaattc atcgaagcaa
    31981 atccagtaag cggaacgatt gaagcggaca atacgtatgt aaaaatcgaa ttagttggta
    32041 aaggcgcaca tggtgcaagc ccacaatctg gtatcaatgc aggttctttc ttggcattgt
    32101 tcttagataa ctatgaattc ctaggatctg ctaaacaatt tatccatgta gcagctgctt
    32161 atgtccatga agatttttat ggagaaaaac taggagtcgc ttatgaagat gaaaaaatgg
    32221 gcaaattgac aatgaatgct ggactatttg cttttgaaga aaatggtaca gaggaagcga
    32281 acttcatcaa tatgaatttc cgttttccaa aaggtgtaac agtagacgga ttgcaaagtg
    32341 acatcgaaca aacagtgggg caagaaggcg caacagttac tcgaggtgct cgcgtaatgg
    32401 aaccacatta cgtaccaatg gatgatccat tggtggctac attattgcaa gtctatgaag
    32461 accacactgg agaaaaaggc tacgaacaaa tcatcggtgg cggaacttac ggacgtttgt
    32521 tgaaacgtgg cgttgcttat ggagcgatgt tcccaggata tactgataca atgcatcaag
    32581 caaacgaatt tatgagtctt gatgacttgt tcagagcaac agcaatctat gcagatgcca
    32641 tctatcgttt ggcgaaataa aaatactaaa aaactccggc tatctctgac agctggagtt
    32701 tttatgttta aaaatgaatt agtacatcgg tattcttaaa agtaatttag ttcgtctttt
    32761 gatttctcag gagggatcaa aaaggcgaaa gcactaagta tagcaaaact tgtgatgatt
    32821 tgcgtacgat acgtaaacca ataatgaatc tgtgagtgat tagctaaaat attgtaccaa
    32881 atatacggcg ttacagcagc taaaacaaac aaaactagaa gttggaacgg acgccagcta
    32941 tttcgtttac gataagcaaa atagagaaaa acaagacaag taatcaatag caataatatt
    33001 gctacttttg gatacatcaa tctaatattg cttttcagca tctctaatcg atgcaacggg
    33061 tatttgtcgt ttccttccgt tcgaaagagg atttggttga ttgcatcttt tacaatgttt
    33121 ttgttcaata tgatcgatga taggatccat ttagccaccc atgtcaaacc atagcctaat
    33181 ccccaaaaga taccggtaaa aacaaaactg cctacttgtt tgctcaatga actgcgttta
    33241 tccattaaat acttatttgt tacataataa ataatgatca caggtatccc ccaagagatg
    33301 accggtgttg tcaacaagtc aaaaaagtta gctaaagaac caatgacaaa gaaatacaag
    33361 aataattgtt ggttggtgtt ggagagttgt ggttttgtta aaaatagtaa tacagacaat
    33421 aaagtcaaaa tccaaatatt tgaaaattgc atactgaaga aaaaggttgc agcatttcct
    33481 atagcaagcg aaatcaacaa ggctgtcgtt aaatagatgt cgctacactt ggttaaaaag
    33541 tagctcgtca atccaatcag cagaaaaaga atggctgcgt aaatcattcg aatactcccc
    33601 aaactcatcc ctagcagtaa aggtcgtaaa aaaagctgat aaccatgcca ataacgggga
    33661 taatccgcca tagacatcgc gttctccaag gagttcaatt caggatctgc ttttgttttt
    33721 cgtatcatca aatgatcagt aaaattatct aaccgagtgc ctagcatatt tccttgattg
    33781 atagaaggat acattccttc tttttcaacc atctgtagag atttttctgc attcgattca
    33841 atagagtgct gcggaatgaa aaaagtaatt gtcagtagta cgcaatagct agcgatcaag
    33901 agaacaaaag caaaaaatat ctttttaaat agtttcatga gtatctccta tatctgtttt
    33961 cattttttct cttttatcta gtaaaaaagg agagaggata taaacaggta gacctaatgc
    34021 taaaacaaac acataccgta aactaaaagc cacaggagta gcaatcataa tagtagcaaa
    34081 aacaagcata ccgggaagaa aaaggagtaa ataccgatat tttttcttaa agattgctaa
    34141 aagtgcactg ccgatagcta accacagtaa tgtgccggaa ccaaagaaat cacgagcatc
    34201 gatgattttt ttcattcctg acaatccagt aagatgttca atcaaatcta cttgcttcat
    34261 cccataatta ttcgtgttta cacgagtatc taaaaagccg taactatttt ttgtaccagg
    34321 tacccagaac ccgaacgttt ctaaaatata agcatctgta tagattttta tattacttgg
    34381 taaatttctt gcccatagtg atagaaattc ttttttatgt gtattcaaaa actcattgtt
    34441 aaaattttta tgccacttga ttgagtctgc aagactagga gaatacgctt cataatcttt
    34501 tatcgggagt agctgattca tgaatgcttt atctttctta gacaagtcac catccataac
    34561 aatagttcta gaaatttgct gcaaaggaac acctaattgt tcagcagttt ctgtaggaat
    34621 agcataacga gccatcaacg ggtggatgag tagtccagca atcactgtat aacccagcac
    34681 cacttgaaag aatgcttgat accttttttg tttcaaaata atcaagccgc aaatcaaacc
    34741 tgtgccggtt actacataaa tcccattatt tcttagatag gtggtcagta aagcaaggat
    34801 gattacgtaa atctgattga gaatcgttgg cttttctcgt tgaaaaataa agtcaaaaac
    34861 cgctaaggaa aataaaaagc aagcgataga gaacaaagta tctttttgca tgttcaaggc
    34921 gtagattgga aaaaccggtg caaatgcaaa atagcataaa ctaatgagta ccggaaaaaa
    34981 atggatgttt ctttttaaca gccagcaaag agaataactt atcgctgaag ctgttatcaa
    35041 tgtttgaaaa atcgaaaata aaaatacacc gtgattgatc gtatcagttg gtaaatcatg
    35101 aacaaatagc ttgaccagta aggtgaataa gactggatga tgattgctta taggaacatc
    35161 acccatagat tgggcgaccg aacttaacga atcaggcaaa accactccag gatacaatgc
    35221 caacagataa ggaagccaac acagaactaa aaagacagta aagaataaaa aatattttct
    35281 tgaagagaaa gcctgtgtgt tttgagcagt aaaaaatgtt tccagttttg gcattgataa
    35341 ataaatcgat tgtaaaaata aaaaagaata cacaaaaatg gagaaataaa caagaaagta
    35401 aaaaatactt ccatcagcaa tcgttgtctt tgtatagttt gctgagacat actgaaattg
    35461 tatctgtctg ccaatagaaa gtgtaagagc aaaagctgca gaaaaaaaca atcgggcaat
    35521 agctgcaact ttgtttttta ttgaaaacaa ctctattcca tattgcttaa aagcaagtag
    35581 caaaaccatg gctaaaccaa tgattactgt tggattcaaa gttcctagac cataagaagt
    35641 aaaaaaagca aaacctgacg caaataaagt tgcaaaaaaa gtaggaaata gattctcctt
    35701 tttcttatgc ataaaaaagg cctcctactt catttcttta ttttgatatt cgtggtagac
    35761 atggtataaa ttcaattcat attctttctt ggcatttgtg acgaccgtat ccaaaatcaa
    35821 ccctgttact aatgaaagaa gggctaaagt catcaatcca gtacttaaaa tcgcagaagg
    35881 gatgcgtgta ataaagcttg tcagcatata ttcacgaatc acaggaatcc ccatgaccaa
    35941 tccaaataaa aagaagaaga tggtccagat cccaaagaaa agcaaaggtt tataatcttt
    36001 gcacattttg atgatcatca tgatcacttt gaatccgtca gagaatgtat tcaattttga
    36061 ttcgctacct tcaggacgat cgcgataatc gattggaatc tcaacgaact tgaatttttt
    36121 atctaaagca tgaatcgtca attctgtttc gatttgaaaa ccagaactca taatagggaa
    36181 gcttttgaca aaaattcgat tgaatcctcg atagccggtc atgacatcgc gaatttttgt
    36241 tttatataag taagtaattg tatttttaac cagattattc ccaaaatcat ggaaaggacg
    36301 cttattttca tcaaaatagg ttccatttga tagacgatcg ccaatgacca tatctgcttc
    36361 gccagaacgt aatttctcaa gcaaaccatg tgcagcttct gcaggataag tatcatcacc
    36421 atctaccatc aaataataat cggcatcaat atcaaaaaac atttgacgga ttacatttcc
    36481 ttttccttga cgtggttctt tctttacgat tgctccacct tgaacggcca attcgtatgt
    36541 tcgatcggtc gaattattat catagacata aatatctgct tctggtaatt cccttttaaa
    36601 atcttcaata acagttgaaa ttgtcgcctc ttcgttataa caaggaatga gcacggcaat
    36661 tttttcacgt gattccattt gtcactctcc ttatataata aaactaatct tatttcaaga
    36721 ataccgtata ataactataa atactagcta ttccaagagg aaatagccct atttttataa
    36781 aaattaccca ctataaaaga agtataggat acctctcttt tgaatagtgg gtgcgtattc
    36841 gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa atttctaata
    36901 cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca tcttctattc
    36961 gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata ggttcctttt
    37021 caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac ttgatatttt
    37081 caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt gaagctaccc
    37141 cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag cttagttcgc
    37201 tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg tgcttatttt
    37261 accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat aagctataat
    37321 aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat aagtctgaga
    37381 ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt caacgaatca
    37441 aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc gcttatatgg
    37501 aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc ggcatttttg
    37561 gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca catatggatg
    37621 aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc gtacctctag
    37681 gcggctggaa tccttacgtt gtttctgcac agcgttttac acttaaaacc tctactggta
    37741 agaattatcc atgtatttct tcttccgttc ccccgcattt attgcgagga acaagcggac
    37801 aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca agagaagagg
    37861 caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa acgatcaaaa
    37921 cagccaacgg aaagaatatc atcagcaaat catgggacaa ccgctatggc tgtacaatgg
    37981 tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg attgcaggcg
    38041 cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat aaattcaagc
    38101 cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg aaaaatggca
    38161 cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt ttgatcatgc
    38221 ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc ccttatcaat
    38281 actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac gaaggaatcc
    38341 caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg atgttcagta
    38401 ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt ttggataaat
    38461 caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata aaatctggca
    38521 aaagattgct tttgccagat tttttttata aaaagaggat caatgtttgt tagttcgaaa
    38581 gaaaggtgta taatttaatt gaaaaataca taaacagaaa gtagaggaca aagaatgatt
    38641 atcccaaata gtttagaaga attagcaggc tacgtagaaa ctggaaagag tgtatttttc
    38701 tttactgcca gctggtgcgg agactgccgt tttatcaaac cgcaaatgcc tgaaattgaa
    38761 aatgactttt ctgattggca atttattgaa gtagaccgtg acaagtacat agatgtagcc
    38821 gctgaatgga acatttttgg tatcccaagt tttgtcgtga tccaagacgg aaaagaatta
    38881 ggtcgtctag tgaataaaga tcgtaaaaca aaacaggaaa tcgaatcgtt cctagaaagt
    38941 gtaacaaaag gctgacatct gttaggaggg gtcaagatga atcaagaata taagaacatt
    39001 ttagtaggta tcgacggtag tgaacaagca cttgctgctt tcaaaaaagc ggtagaagtg
    39061 gctcgccgta ataatgggaa agtatatgta gcaaacgtaa tcgatcagca attttataac
    39121 tttatgggct atgcacctat tgatcaaaat ctagtcgatc agcaaactga aacagccaag
    39181 caaatgatcg aagaatgtaa agaatatggg aaatctgttg attacacaaa tatagaagga
    39241 attattgcat atggttctgt tcgtgaatcc atggcagtca aattgccaaa aaaatatgca
    39301 atcgatctaa tcatggttgg gcagtcaggt ctaaatgcag tcgaacgctt tatgacagga
    39361 agtgtagcca gctacgtgat acgtcattca ccttgtgatg tcttgatcgt ttctgacgaa
    39421 gaagaacagc caagtaatta agcaagtgga acttgtacga cctttttaat caattaacta
    39481 aaaaacagta aagggactgt gacaaaagtc ttgtcacagt cccttgttac gaataaatgg
    39541 tgttccagaa gaggcttctt cggaaataaa gcatgaaaaa aatctcatgc agtgaatgca
    39601 attttttgtt aagataaatc tcagcaaagg ataatggagg aaagaacatg atttttgctt
    39661 ataacaaagc acacgtcgga gacaccttga tggttattat agccgacgat aaaggaacag
    39721 aaaacaccgt tgaacgcaaa tggaatgttg ctcggatcaa agatgaacaa ggacaagttg
    39781 ttgcttggaa ctttttccat atctccgatc atctaacaat cgaagggaac ggccaagtaa
    39841 gcttaacaga tgaggaatta gcgaaattga atcgattgat caaagaagca ggattcgaag
    39901 aacagcttga agctgatcat gaaccgaaga tcgttgtcgg gtacgtaaaa acatgcgtcc
    39961 cacatcctga ttctgaccat ttatcgatta ctgagacaga agtagacaat ggtacagtat
    40021 tgcaaatcgt ttgcggtgca cccaatatcg aagctggaca aaaagttgtc gttgcaaaac
    40081 caggagctat gatgccagat ggaatgatga tctggccagg aactttgcga ggggtagata
    40141 gctatggaat gatctgttcc gctcgtgaat tgcatttgcc aaatgctcca gcaaaaaaag
    40201 gaatcttagt attgcctgag gatgccgtag tcggagaagc atttccaaaa taaagaggtt
    40261 gtgacaagtc tttgtcacaa cctctttttt attaattttc actattttga ttttgtttta
    40321 atgccgattg atcgatcgtc aattcaacag tagttgtttt ttctttcgag ccttcatagt
    40381 aagtgatttt gacagaatct cccacttttt tcttatacaa agcagattga agttctacac
    40441 cagaagaaac ttctttgtca tcgatcttag taatgacgtc gtattgtttc aatccagctt
    40501 tttcagccgg tgtagctgtt tggacatttg tcacgatgac accgttagtt acagatgaag
    40561 gaatcttcaa gatttgttct tgttgctgag tagaaacggc agataagtcg accattgtga
    40621 tacctagagc tggacgtgtc acttttccgt ctttttccag ttgattgatg atattcacta
    40681 catcgttact tggaatagca aatcccattc cttctacgct tacattagaa gtagattcag
    40741 aagtacttgc gatcttactt gagttgatac cgataacttg tccttcgata ttaactaaag
    40801 gaccaccaga atttccaggg ttgattgctg catctgtttg gatcgcattg atattgactg
    40861 tttcgttcga ttcattcgta cttgtcactt gtcggttcaa ggaagaaatg attcctgaag
    40921 tgacagaatt tgcatattca gatcctagtg gggaaccaat cgcaatcgca ggctcaccaa
    40981 ccttcagagc acttgagtca ccaaaagagg caactgtttc gactttgtct gaattgatct
    41041 tcaacaccgc taaatctgaa taagcatctg ttccaactaa ttcagctttt accttcgtac
    41101 cgtctttcat caagacttca agaccttgct ggccatctac tacgtgatta ttcgtgacta
    41161 cataagcagt attcccgtct tttttgtaga tcacgccgct tccttcacta taagcttcca
    41221 aattactatc atctgagctg ctactttctt cttgctgccc gaatagtccg ccaaaaccgc
    41281 ttgattggtt ttgactttgt aagttgataa cagaaacgac agcgtcttga actttatcta
    41341 ccgctttggt gatatcagaa tctacattga ctttgacatt ttccacaact gtttcaccgg
    41401 cagaattctg attgccgctt gtagcagtag aactattgtt gccagtgccc atcgctgcat
    41461 aaaaaatgcc agctgtcagt agtcctccaa cgatccctcc aacaagcccc agacctaact
    41521 tacgccagag gctattattt ttattttttt tcatctttgg tgtcacattt tttctatcca
    41581 tgtgttcctc ctccaattac attcatttat ctactgttag tatactctta tttgttgact
    41641 ttagtctact ttgagactgt gaacttttta tgaaaaactt taggaaaaac cattgttttc
    41701 agatgaaaat atttgatttg cttttttcca aagaaactgt gtaaaactac gcggatagga
    41761 ttggaaaaat aagggataaa acatatccac agcctgtgta taaagtggat aaattcttat
    41821 aaaacgtatg tttgcctaat gaatgtgatg aaataaggta aaataacact gttttctgtg
    41881 gataaacctg tggatgttgt gcataactgt tggggaaatc tttttaacaa aaatagccaa
    41941 aataaacata tagacgaaaa aattgattat aataaacaaa gtgagcatga agaccaaagg
    42001 agagaaaaca tgaatatcaa aattatttca gtaggaaaat taaaagaaaa atacttgatc
    42061 caaggtatca atgagtatgt caaacggctg aatgcctatg caaaaatcga attgatcgaa
    42121 gttcctgacg aaaaagcccc ggagaattta agtgaagcgc aaatgagaca agtaaaagaa
    42181 aaagaaggag aacggatctt agcgaaaatc aaagaacaag aatatgtcta tgccttagca
    42241 attgaaggga aaaatcccac aagcgaatct tttgctaaac aaatcgacca attaggtatc
    42301 caaggaaaaa gccaccttgt ttttgttatc ggcggctctt taggactcag cgaagccgtc
    42361 atgaaaagaa gcaatgctca gatctctttt ggcaaaatga cgtatccaca tcaattgatg
    42421 cgtctgatcc tcgtcgagca aatctaccgt gcctttcgga tcaatgcggg ggctccatac
    42481 cacaaataat gatatttttt aagagaaaaa ttatcc
//
LOCUS       DAIGTA010000019        41772 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.019, whole genome shotgun sequence.
ACCESSION   DAIGTA010000019 DAIGTA010000000
VERSION     DAIGTA010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.019"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(71..472)
                     /locus_tag="NOB43_001081"
     CDS             complement(71..472)
                     /locus_tag="NOB43_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI0981957.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(558..764)
                     /locus_tag="NOB43_001082"
     CDS             complement(558..764)
                     /locus_tag="NOB43_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981958.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(859..2361)
                     /locus_tag="NOB43_001083"
     CDS             complement(859..2361)
                     /locus_tag="NOB43_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HCI0981959.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(2379..2834)
                     /gene="argR"
                     /locus_tag="NOB43_001084"
     CDS             complement(2379..2834)
                     /gene="argR"
                     /locus_tag="NOB43_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI0981960.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(2932..3549)
                     /locus_tag="NOB43_001085"
     CDS             complement(2932..3549)
                     /locus_tag="NOB43_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCI0981961.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            3770..5143
                     /locus_tag="NOB43_001086"
     CDS             3770..5143
                     /locus_tag="NOB43_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0981962.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            5218..6330
                     /locus_tag="NOB43_001087"
     CDS             5218..6330
                     /locus_tag="NOB43_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCI0981963.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(6402..8039)
                     /locus_tag="NOB43_001088"
     CDS             complement(6402..8039)
                     /locus_tag="NOB43_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HCI0981964.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELYLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(8207..8815)
                     /locus_tag="NOB43_001089"
     CDS             complement(8207..8815)
                     /locus_tag="NOB43_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0981965.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(9199..10350)
                     /gene="queG"
                     /locus_tag="NOB43_001090"
     CDS             complement(9199..10350)
                     /gene="queG"
                     /locus_tag="NOB43_001090"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCI0981966.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(10369..11121)
                     /locus_tag="NOB43_001091"
     CDS             complement(10369..11121)
                     /locus_tag="NOB43_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981967.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(11262..12212)
                     /locus_tag="NOB43_001092"
     CDS             complement(11262..12212)
                     /locus_tag="NOB43_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCI0981968.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(12213..13052)
                     /locus_tag="NOB43_001093"
     CDS             complement(12213..13052)
                     /locus_tag="NOB43_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0981969.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(13049..13795)
                     /locus_tag="NOB43_001094"
     CDS             complement(13049..13795)
                     /locus_tag="NOB43_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0981970.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            14033..15403
                     /locus_tag="NOB43_001095"
     CDS             14033..15403
                     /locus_tag="NOB43_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0981971.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(15458..16354)
                     /locus_tag="NOB43_001096"
     CDS             complement(15458..16354)
                     /locus_tag="NOB43_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0981972.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(16468..16638)
                     /locus_tag="NOB43_001097"
     CDS             complement(16468..16638)
                     /locus_tag="NOB43_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981973.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(16635..17312)
                     /locus_tag="NOB43_001098"
     CDS             complement(16635..17312)
                     /locus_tag="NOB43_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI0981974.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(17403..18308)
                     /locus_tag="NOB43_001099"
     CDS             complement(17403..18308)
                     /locus_tag="NOB43_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0981975.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            18483..19937
                     /locus_tag="NOB43_001100"
     CDS             18483..19937
                     /locus_tag="NOB43_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0981976.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            19953..20984
                     /locus_tag="NOB43_001101"
     CDS             19953..20984
                     /locus_tag="NOB43_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0981977.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            20991..22178
                     /locus_tag="NOB43_001102"
     CDS             20991..22178
                     /locus_tag="NOB43_001102"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCI0981978.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            22334..23716
                     /locus_tag="NOB43_001103"
     CDS             22334..23716
                     /locus_tag="NOB43_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI0981979.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            23843..24073
                     /locus_tag="NOB43_001104"
     CDS             23843..24073
                     /locus_tag="NOB43_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981980.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(24273..24941)
                     /locus_tag="NOB43_001105"
     CDS             complement(24273..24941)
                     /locus_tag="NOB43_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCI0981981.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(25130..25927)
                     /locus_tag="NOB43_001106"
                     /pseudo
     CDS             complement(25130..25927)
                     /locus_tag="NOB43_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(26208..27587)
                     /locus_tag="NOB43_001107"
     CDS             complement(26208..27587)
                     /locus_tag="NOB43_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0981982.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(27762..28931)
                     /locus_tag="NOB43_001108"
     CDS             complement(27762..28931)
                     /locus_tag="NOB43_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0981983.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(28906..30057)
                     /locus_tag="NOB43_001109"
     CDS             complement(28906..30057)
                     /locus_tag="NOB43_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCI0981984.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(30017..31378)
                     /locus_tag="NOB43_001110"
     CDS             complement(30017..31378)
                     /locus_tag="NOB43_001110"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCI0981985.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYGTVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(31375..32376)
                     /locus_tag="NOB43_001111"
     CDS             complement(31375..32376)
                     /locus_tag="NOB43_001111"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCI0981986.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(32392..33087)
                     /gene="dapD"
                     /locus_tag="NOB43_001112"
     CDS             complement(32392..33087)
                     /gene="dapD"
                     /locus_tag="NOB43_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HCI0981987.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(33093..33809)
                     /locus_tag="NOB43_001113"
     CDS             complement(33093..33809)
                     /locus_tag="NOB43_001113"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCI0981988.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(33806..34687)
                     /locus_tag="NOB43_001114"
     CDS             complement(33806..34687)
                     /locus_tag="NOB43_001114"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCI0981989.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(34690..35490)
                     /gene="dapF"
                     /locus_tag="NOB43_001115"
     CDS             complement(34690..35490)
                     /gene="dapF"
                     /locus_tag="NOB43_001115"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCI0981990.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(35477..36736)
                     /gene="lysA"
                     /locus_tag="NOB43_001116"
     CDS             complement(35477..36736)
                     /gene="lysA"
                     /locus_tag="NOB43_001116"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCI0981991.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(36951..37121)
                     /locus_tag="NOB43_001117"
     CDS             complement(36951..37121)
                     /locus_tag="NOB43_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0981992.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(37222..37785)
                     /gene="efp"
                     /locus_tag="NOB43_001118"
     CDS             complement(37222..37785)
                     /gene="efp"
                     /locus_tag="NOB43_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCI0981993.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            38213..39130
                     /locus_tag="NOB43_001119"
     CDS             38213..39130
                     /locus_tag="NOB43_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HCI0981994.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            39143..40288
                     /locus_tag="NOB43_001120"
     CDS             39143..40288
                     /locus_tag="NOB43_001120"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCI0981995.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            40459..40917
                     /locus_tag="NOB43_001121"
     CDS             40459..40917
                     /locus_tag="NOB43_001121"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCI0981996.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            41076..41546
                     /locus_tag="NOB43_001122"
     CDS             41076..41546
                     /locus_tag="NOB43_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCI0981997.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(41599..41714)
                     /gene="rrf"
                     /locus_tag="NOB43_001123"
     rRNA            complement(41599..41714)
                     /gene="rrf"
                     /locus_tag="NOB43_001123"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        11729 a         8637 c         7617 g        13789 t
ORIGIN      
        1 tttgtcaaaa aaaaccagac aaaaagcggt cctttcacgt ttttagtctg gttcgatttc
       61 ctttattctt ctaaacaatc gttacttcta catcgatatt tcctctagtt gctttggagt
      121 aagggcagaa ttcatgcgca tcttctgcaa ttttttgggc ttcttcttcg ctgatgccat
      181 cgatatgcac ttctaatact acaccgatct gatagccgcc atcatctaaa ttataaagag
      241 agacacgtgc ttttactgtg gactctgctg tcattcctgc ttctttgatc atatgttgta
      301 ccgccccatt gaaacaagaa gcataacctg ctgcaaataa ttgttctgga tttgttcctt
      361 ctgcatggat tcctggagga gtgattttca tatgcatcga gccatttggt gcctcgactt
      421 ctccattgcg cccgccatgg ttgatcattg ctgtttcgta tgcttttttc attgtactgc
      481 tcctttcgat tgaccatttg ctacttggct ataattatag tgtatgacaa gtaaggcgct
      541 ttctacaaaa attctgctta ttcgaatacc agaatgccgt cttctactat ttttccaaaa
      601 aacaaaaaaa tactactcgt gaacaacagc gtcatatttg ttccaaaata aatagcaatc
      661 ttttctacat aatcttttat atgattgatt ttaagataca tatataccag aaagttgacc
      721 ccataaacca atactgttaa aaaaataacc atattcgtta ccattttttc ctccttttgc
      781 tggtctccct accagcactc gatttaacca taccactttt tttgccgtcc aagcaactag
      841 cctttcaaaa agactggttt attctgctgt taatgattca agatcagaaa aatgtccgaa
      901 taattttgct aattttacta acgccaactt gttctttccg aattcatcat tttctatctg
      961 taatactagt aacggctcat gtaagcttaa acggatcaaa aaccagccgt ttccgtatgg
     1021 ctcttctaga tcatatcgaa taccttcttc attttccggg tcgaagttca tccctttttc
     1081 ttcttccaac agtcgcttca tttcttctaa tatcttgttt ccttgttcgc gtggttcatc
     1141 gctgaacaat tttaatcgga tttcttgtac ttctacgggc tgtttcaact ctttgatttg
     1201 ttcatctaat gtgatacctt ttctttttaa ttctggcaaa agcatcagga tctttgcgat
     1261 gacatatgca ccatcatcca gaaaatagtt ttccttgaat gcagcgtgtc cgcttgtttc
     1321 gatggctagc tgtgtatctt tcccaagacg gttaagttct aatgctttat tgattacatt
     1381 tcgatagccg gaaatataac gaacttggat gcctcctttt tcttcaatga atctttgtag
     1441 atgagaagaa gtaggggaat tcgtcacgat tcttgttcct ggatgctctt ttaatacgat
     1501 tgtacttaat actgcgatca aattatttcg attgatcact gttccagaag cactgacaac
     1561 tgcagaacga tccacatctg tatcgaaaat gatcccaaga tctgcttcat ttgctaaaac
     1621 agcctgcttg atactttcca tcgcttcttt attatcagga tttgggatat gattaggaaa
     1681 tcggccatct ggttccaaaa attgggaacc tgttgaatcc gcacctaagc tattcaatac
     1741 tttttcagca aagaatccac cagcaccatt tccggcatca acaatgattt tccaaccatt
     1801 tagtggtttg ctttctagtg ttccaatccc ctttttaatt tttgtgacta aatcttgcgc
     1861 ataaggtgtc aaaaggtctg ctttttctac gcttccagtt tgttcgcttt ttattttttg
     1921 ctgctgtgat aggataaaag caatatcttc tttttctgct cctccttctg aggtaaagaa
     1981 ttttattcca ttataataat agggaagatg gctagcagtc agcataaccg cagcatcgca
     2041 cgagaactgt tcaaattgag tggacataaa catagcaggc gtagtagcta attcgaaatc
     2101 gatgacatgt atcccttgtt ctttcagact ttggatcaac gcctctttca gtgctggtcc
     2161 gcttatccta ctgtcatgac caatcccaat cgtccatttt ttatttggat cggttgattt
     2221 cttctttttc tttatccagt ttgctagtcc ccagccgatc ttttttacca tgtctgtcgt
     2281 caagtttact tcatatcctt caactggtaa tgcgattcct cgaatatccg atccattttg
     2341 cagcgctttc atatctttca tataaaagtc ctcctcattt attccctcat tttttccagc
     2401 ttttctgcaa atcgctgtgc ttcttcttct gagcggcaaa taataatgaa tgtatctaca
     2461 ccggccatcg ttccgacaac ttcagggtaa gccacttcat ctagccaatt cgttaccaca
     2521 tcggcaccat ttcgttcagt caatacgata accatgaact gaacagactg gatacgcaaa
     2581 acctcgcgtc taattgctgt acgcaaacgt tcttcattta aagaaacaga tggctggtta
     2641 aataatgtat agcgtactat tttgttttca ttttgacttt ttactaactt catttctcga
     2701 atgtctcgag aaatcgttgc ttgagtcaca tcggcgcctg cttcatgcag ccgcgcaagc
     2761 agctcttcct gtgtcccaat aggttgttct gtaatgatct ggcggatcag tgcttgtcgc
     2821 tgtttctttt tcatattaga cacctctcaa tgttgattat agcaaaagat aagtaatatt
     2881 tcttcatatt ttggtatttt ttacttttat tttttgtttt cattcaggtt gctaaccttt
     2941 ttctatttta acacgcaaaa tcgtcttcat tttttcaggt gctgattttc ttggatcgct
     3001 gatgtaaatc tctttgtgtt ctttagaagc tctttcatag ccttcttttg cgatgaatgc
     3061 ttctaatttc tcaaacgttg ctggttcttc ggcatagggc ccgacgtgta agatttgggc
     3121 acaaagacct tcttccatct ttttgaatac tacttgttct ttcaagtctt ccggaagttt
     3181 gctagaacgc tgaatggctt cttgtgctat cgcttctgta acaaagtcag gctgtcggat
     3241 catcaattga taagaaaaat gttctttttt catcactggt tcatgcaaat acttttcttg
     3301 cagtccccat tgtccttcca gtggatagac agtatacatc tgataatcag gaatcagcca
     3361 atttttttta ggcgacatgc gtattgcata gctgactgca tatagacagg ctactcttcg
     3421 tttaaagtct tcctgattcg ggtcgccgat ccctctgatg ctaaagaatg attttttagg
     3481 aacctctagt atttgcgggc tttttttcat actatagctc ttatctttac gccattcaat
     3541 tttttccatt tttcttcctc cgcgaaattc catttagtta tttattatca tacctctttt
     3601 tgagtgactt ggctaatcgt gttgacacta tttttcagtt tgtgctagaa taagtgaagt
     3661 aaataaatcg tacagataac acgtttcggc gtgtcgagag agaggcggtt tctattttta
     3721 taatagaaat cactctcttt ttttacgaaa ttttttagag gtgatgtaaa tgacaaaaca
     3781 aaaacagctg cttttagtac ctgcagtaat tgcaacaggg atgatgtctt ttgcgggcgt
     3841 attgatcgag acggccatga atgtaacttt cccaactctt atcagacagt ttgatttaac
     3901 gactgcacaa gtccaatggg taacaacgat ttatcttttg atgatttcga tcattgttcc
     3961 gctgtctact tatttgaatc gcaattttag tctcaaaaaa ctctttttag cttcaaatct
     4021 gcttttcttg gcaggtataa tgatcgattt cttctctcct accttcatgg tcctattgtt
     4081 tggtcgattg ctccaaggtg cagcgacagg tatcgctctt ccgttgatgt tccatattat
     4141 cttgacattt gcccccctca atcgacgagg cgcgatgatg ggtgtcggta ctttgacaac
     4201 ggccattgct ccagcaattg gccccactta tggaggcatt atgacttcac attttacatg
     4261 gaatcatatc ttcctgtttc ttgtgcccgt tttgtttctt tctttgatta tcggctggtt
     4321 tgctattccc gagatggcag tacaaaaaag tggttatttg gattggataa gcgttttagg
     4381 aatttgtctt ttgtttagtg gaagtctaac atttttgagt acgttgggaa cagtttccag
     4441 ctggattgct ttaatcatcg gcggtattgg ctggttcctt ttttactatc gaagtaaaaa
     4501 agtggagcat ccactgatcc gactgtctat tctttcaaat aaaacattcc gcttgttttt
     4561 gattggcttc ttagtttatc agtttttatt acttggtgta tcttttgtct tgccgaattt
     4621 ccttcagatc gttcaaggaa gtagtccttt tgtcgctgga ttagcgatgc ttcccggcgc
     4681 agcggttggt gctttgcttt ctcctttttc cgggaaaatg ctggatcaat atggtccgaa
     4741 gaagccaatt tttgctgggc tgattctttc tttgattggt tggctagcat tattcctact
     4801 cataggacac gcttcagtgg gtgtattgat tgcttgtcat gtgttttata tgatcggtat
     4861 cggattatct tacagcaata tgatgaccac cggaatgaat gcactgaatg aagaactaca
     4921 aggagacggg aacgcaatgt tcaatacctt gcagcagttt tctggcgctg tggctacttc
     4981 attagtagcg gtcattatca attacgtcca gcatcatact tcccataact atgaagtgtc
     5041 tactacatta ggatcaaaag cagcattagg cgtcttgttg ctgttgcttc tcgtaagctt
     5101 tgctcgattc gcctattatc tgttctttgc taaaaaagcg tagattccat atacggcagg
     5161 tgttgcatct gccgtttttt tgtgtgaaaa tggttgtttg taaaaggagg cttttttatg
     5221 gaaaaaattg ccattatcgg tggcgggatc attggtatga ccctagccag ttacttagat
     5281 acatcaaaat tcaatgttgc tttatttgat gaagggacag gacaggcaac taaagctagc
     5341 gctgggatta tctccccttg gttgtcgaaa cgcagaaaca aacaatggta tcgtctggct
     5401 aaagacggcg ctgctttttt ccctaaactt ataaaagatt tccaacttga tcaaacgatt
     5461 tacgcacaat cagggacact tttgcttcga cctgaaaaag atttagctga attggctgtt
     5521 cttgccgaga aacgaaaaga agaagcgcca gaaattggaa acatcgaatg gctttcacct
     5581 gaacagacat ctcaagcact tccgttattg aaaccagcag tttcactgcg tatcagtggt
     5641 ggtggtcgtc tggatggaaa agcatattta gaacatcttg gtcagcgttt agcacaaaaa
     5701 caaatggagc agatccaggc aaaagtcact ttgcataaga agagcgattc ttggctcatc
     5761 aagggaccgt ttggagaata cacagctgat cgtgtaattt tgacacctgg cccggcactt
     5821 aagcctttat tacaagaatt aggctatgct gcagatatac gtccgcaaaa agggcagctc
     5881 ttagcatttc agacatctta taagatgagt caagactggc ctgttgctat gcttgacgga
     5941 gaagctgatt tcattccttt catggatgga aagatccttt taggtgctac ccatgaaaac
     6001 gatcaaggct gggatttggc tcctactagc gaagcttata agggattgac taagagtaca
     6061 gaacagttct tgactgatcc agatcagata aaaaactggc catacgagtt ccgtgtaggt
     6121 acccgtgctt atacgtcaga tttttcccca tttttcggcg tactgccaga tgatccaagc
     6181 ttactggctg ctagcggtct aggctcttct ggcttgacca caggtcctta tatcggctat
     6241 ctattagcca acttcttaaa tactggtcat tggcctacgg aagattatca aaaggacatc
     6301 tccacctata ttacgaaaaa tccatcatag aaaaacagct ttttcaagta aggatcccga
     6361 gcgatattgc gcatggatta cttcttgaaa aagctgttat tttagttcaa tttctgaatc
     6421 aaattctcca aactttcttt tgcttcatct ggcaagagat cttttcctat ctgagcttca
     6481 atgaatcgta aacgaatatc aagtcgttgt ttcaccagat ttttatagga cgtatcctca
     6541 aaagaaacag gaaaatctgg tataggtaaa tagtggatgt cttcaaatgg accaaacgac
     6601 ttgaattctg ccgtttgttg cacgattctt tcaacgattg acaatgtcgt ttcaggtttg
     6661 atttttttat catcgaaata tccagtattc aggacatagc aggctgtttg ctgtttcaaa
     6721 aacaactctc gaaaagcttg atagtcttcc ctaagaggat agacacggaa aggattagca
     6781 aatggttcaa tgactagctc atctagctgt ctttttgtag tgatattttc cgcgtctgat
     6841 cgttttgttg ctaatgttgc accaaaagac gctgctaaaa ctgggtcatt gatcttgata
     6901 attggcggaa gcgaatcatc tttcatgatc caaaaaacag catcgatctt ttcgctaaga
     6961 tgatcgactc ggtcgggtgt cgcataacgt gatttgactg tccgcccatt tccgtttcgt
     7021 atatctcctg ttactaggac tttttctcct ttacttgtac atgtcacgcc cacattctga
     7081 caagtaagga aagaagaaat ggccggatca tcagacggat agtcttgtgt tttatcaaag
     7141 taagaaggtt ccaaggcagt agcaaaacca ttttttcgag aaataacgaa agcatcgtca
     7201 tgcaagatcg aaacagagtg accttccgta tgttttgcta aggtaatcgt tgattttcca
     7261 gaaccggaca acccaaatac agccatcgta taggtctggt cattactagc atattgtttc
     7321 atcccaccgt ggcaggcaat aaagccattg cgatttccca atgcccaagc aagcgtcaaa
     7381 gtcgcttttt ttaattctcc aaagtaacgt aatcctagca cagccgctgt attatggaga
     7441 gcatcaaaca aaatgagtcc atttggaaat gtttcatgtg tccattcggg atcacaaaag
     7501 atataaagat ctccctcatc aaaggaaaca gacttttgat aagtctctaa gatcttcgaa
     7561 ttcgctggct gaaaattcag caaataagaa tacaaattgt tctcaaatcc ttctggaatc
     7621 agcaaatgac tttgcacaga aaattcttca gataggccaa cgattacttt tgtatggtaa
     7681 aactggcgct tgcgactttg atacacagct tctcttaaaa ttttctcgta tttgctttgt
     7741 tccttgtcta agtcctcaaa gatccgccga gcacttgctg ttcttcccac aatgcttcca
     7801 tcattgaata ctagtgtcct aacatcagct ggtaaatata gttcttcagc atgtgagatt
     7861 gttaaatctg tgatgatcgt tcctggactc ccttttgcta gttgataagc tgtcttccta
     7921 tcaaaaactt catgaacatt attaccgtaa aatgtcgttt ctacaatcga tcgaatactg
     7981 gataacagtg gatttccact tgtgatttcg tttaattcga gactctcttt tgtactcatg
     8041 gctcctcctc attccctaaa caaaaaaacg ttttctttat tatacattat tcgagttttt
     8101 atttgtactg ctgcgctgtg ggaagcaaac gagttatttt tcacacaaaa aaaccgagaa
     8161 cttgaataaa caagtttctc ggtttcatca ttttcctttt atcggcttag taccagccgt
     8221 ttgctaacca gaatgtttta gcagcatccc atgaaccata acgagatgtt acatattgtt
     8281 ctgctacacg ttcttgattg gcagctgaat agtcgccgtt taagtatgaa gcatctaatt
     8341 gataacggcc gatgtaacgt ccgttagtag ctgtgtatga accgcctgat tctttttgtg
     8401 cgatccattc ttttgcagag cttgaagttg gcgctgttgc agcagctggg gcagcaggag
     8461 ctacttcaac tgtttcaaca ggtgcaacgt atgtatgttc ttgcgttgct gtttcagttg
     8521 tagatgctgt attttctgtt gttttgtttt ctgttgttgc tgaagaatca tttgaagttg
     8581 ggattgttaa ttgttcacca acataaatgc ggttgatgtt tgcgatcgaa tttttttcag
     8641 caattgcatc gatcattgag ttgtctcctg caaatttttg tgagatctta gataatgaat
     8701 cacctgattt tactgtataa acttcatcag cgtgagcatt tgtagttcct acaaacattg
     8761 cagtagcacc agcagcaaaa gttgtaccta aaacaatttt cttaaatgaa ttcatattaa
     8821 actccttttt ttctccgttt tttattcttt cgacgctatt aactttatca tttagaaata
     8881 tttcataggt aaaagaaaca tgacatttaa tgacaaaata acgaattatt taatatttgt
     8941 aacatttaaa caaatatttt tttgatacaa aaccataaaa gccttgttgt ataagcaaag
     9001 taatcgtttt tctatgtttt tttatttttg aatgaaaaac gcagattctg taacattcac
     9061 tgcaataatc cataaaaaaa agcaaaaaaa tttttgattt ttatcaaatt ctcttaaaaa
     9121 aatgtaaaaa atacaaaaaa accagtaatt gttacaacaa ttactggaca aaaactttga
     9181 ataatgttaa ctattttttt attttaactt tctccgcaat aatttctggg catgttccaa
     9241 ttcgtttata acgacttctt ctgtttcttt agctaatatt tcatctaata catcaagcca
     9301 tttttccggt tcttttgttc ctagacgtcc aatagcccaa gctgctgttc ctctgatgac
     9361 agggcggaca tctgttaaac attctgaaat ctcaggcaat gccgttcgat cacctagatt
     9421 agctaaagca atcaatgcgt ttctctgcaa aggtttcttc ccacgccatg aaccagctaa
     9481 atgcccaaat tgctgtttga agtctttatt agacatcgaa agcattggct ttaattttgg
     9541 atatatttcg tctacttttg gttccatctc ttcatgaaaa tgaaaatctt ttccttgatt
     9601 gtaagggcag actaactggc agatatcaca tccataaatg acatttcgca tttttttacg
     9661 atattcttcc ggcatcatcc cttttgtctg agtttgataa gacaaacatc gctgggcatt
     9721 cattcttccg tcaccaagca atgcttttgt cggacaagca gtcacgcagc gcatacagtc
     9781 accgcaacca aattctcctg gtttatcagg ctcaaataca atattagtaa cgatctcacc
     9841 aagatagaca aatgaaccga actcttcagt gatcaacaat ccgtttcgtc caataaatcc
     9901 taaaccagct cgctgtgcta cagcgacatc gatcagttct ccagtatcta cttgcggagc
     9961 tagacgccat tcctcttctt tttgccattt ttctgctctt gtttggatga attcgatcaa
    10021 tcggttcaaa cggtctctga gtatatcatg gtaatcgatc ccccaagaag cacgagcaaa
    10081 ctgcccgcgt ttttcatccc taggcacttc ttcatggatc ctagtaggat acgcaagtgc
    10141 aatggaaatg atcgatttcg gctgatcaaa tgtcatttct ggataaagac gctcatcgat
    10201 atttggatgt tcaaagccag aagtatggcc agctgctttt tgttcttcca acgattcttt
    10261 taatgaatca aaaggttccg ccgtggtgaa cccgattttg tcaattccta atcgtttgct
    10321 ttcttgtatg atttcttctt ttaatgtcat ggtcttcctc gcttgctgtt aacggctgta
    10381 taacccataa tatagttttt cttttttcag ctggacaaac tggatctgct gatcggcaat
    10441 cttcttttct tccatccatt tttttcttgc agcaaatact tcccaataat ttgttgaaat
    10501 taattttctt ttgttatcta atgcattaaa aaaattcaat gaaactggtt ttgtacttaa
    10561 cagttcatgg agccttacct cttcccatgg cgaaaactca gacagatcgc gggaatacaa
    10621 tacttcttca tagagatttt tttgctgtgt gtacgtgaat gtttgcggga ttttcccagg
    10681 cctagcaatt tctactagac gattataaaa catattcatt aatttgctgt tggcaataaa
    10741 ttgactttta taataggccg actggatctt tttgattact ccttctgctt tgatgactga
    10801 aaataatgca ggccatgctt tgacggttat ttcgtcgttt tgtttaacta atacgccagg
    10861 tgtgaagccg actggagaaa ggaacacaaa ataaccgata ccggtatttt catctaaagg
    10921 ctgaaattca tcaaacaacc atttgcctat gtacagctct tcatctggtt ctgttgtctc
    10981 attttgattt gctatgaata atttagctaa ttctgcttca agaaattgaa ggtcttgatc
    11041 cttgtcggta ttttcctgct ggctgatcaa tcgaaagact tcttctttaa tcgtatattt
    11101 atctttacgt gtaaaattca tagccacacc ttccttcctt actctaacta taacggaatt
    11161 tcttcaaaaa aggtatctgt acgacgaaaa acagcataat tttttttcat atctcttata
    11221 aaaaatgcaa ggtctgctcc tcaagctaga ccttgcactt ttcagctttc ttttgtttgt
    11281 gacaaacctt catggatcgt ttcaatattc catttcatca tctgatagta agaatctcct
    11341 tgttctcctt cttttgctat ggaatcagtg aacagtttat catagatttt caaacccgtt
    11401 tcttttgcta cccgttccat gcttcttgag tctacactgg tttccacgaa taaaaccggt
    11461 acttcttttg ctcttatctg atcaatgatc gctttcattt gatcaggcgt accttgactt
    11521 tctgtattga tctcccatat ataagctgct ggcaaatcat atgctcgtga aaaatacttg
    11581 aatgcccctt cacttgttac taataatttt ttgttctctt cgatagaagc aaaactttcc
    11641 ttcgcttgtg tatctaattc ttttagtttt tccacatatg cttctgcatt ttttttatag
    11701 agtgtcgcat tttctgcatc tttttcagag aatatacgtg cgatttcctc cacatatttt
    11761 attccgttag ataggtctag ccaagcatgg ggatctgctt ttgtatgttc ttcaccgcta
    11821 gttaaataaa gaggttctac atttttgcta actgcaaaat aatcttttcc ttcttctttt
    11881 ttagccgttt ccatcaagtt atcgaaccag ctgttacctg tttcaagatt caaaccgttg
    11941 tataaaataa catctgcatc gcttgccttt ttgatgtctt ctggtagtac ttcatattca
    12001 tgcggatctg ttccgactgg tacgatactg tggatatcta tttgatctgt tccgacctct
    12061 tttgccatgt ccgccaagat cgaattggta gccacgactg acaacttttc tttacttcct
    12121 tcatccgctt ggtcagaagc ctgctttccg caaccggcta ataccaagaa actaactgcc
    12181 aagattaaaa agagtgattt ttttgttttc atctatctgc ttcctttctg aaataaaatt
    12241 ccttttgttg gagaaaataa aaaagcaagg ataaaaaatg cggtacatgc taacacgatc
    12301 gtagctcctg atggccaatt gtaactataa ctgaaaaaca caccgacaac tgcacttagc
    12361 ataccgattc ctgcagctgt aatgatcatt ttcagtaaat ggttcgttag caagtaagcc
    12421 gtggcggctg gtgtgatcaa catggcaatc accaagattg ttcctactgt ctgtaaactg
    12481 actacagcca ctaatgtcaa aaagaacatc aaaagataat ggatcagcga tgtgttcagc
    12541 ccataagctt ttgccattgt cggatcgaat gatgtgatct tcaattcttt ataaaagaaa
    12601 aagacaaata tcaagacgat tccactaacg agtgctgtca gcaacaaatc gctttcccta
    12661 acagctaaga cattcccaaa taaaatatga tacaaatctg tcgcactctg ggcatatgaa
    12721 atcaagataa tccctaatgc aaaaaaggag ctaaagacaa ttccaatcgc tgtatcattt
    12781 ttcaatcggc tccgctgagt cacgaaacca atcactgctg ctgttagcat cccaaaagca
    12841 gtggctccaa agatgtaact aaaaccaaac atataagaaa tggctacacc tggaagaact
    12901 gcgtgagaga tagcgtctcc catcaaagac atccctcgta aaataataaa agaaccgatg
    12961 actccagaag caagtcctac aagcatggaa gtgaccaaag cgtattgcag gaattgataa
    13021 ttcattaatc catcaataaa ggattggatc attttttctc tcctcctttt actaaatgtc
    13081 tgatgatctc accataggcc aattgaaggt tcttcgatgt aaagacttct tgtactggac
    13141 cggaagcgat cagctgttta tttaaaagaa taacctcatc gaaatattct tctactttat
    13201 gaagatcatg atggacgatc aaaatcgttt ttcctgaatt cttcaattcc tgcaagatgt
    13261 caaagatctt tcgttcactt aacgcatcaa tccctacgaa tggttcatct aaaaagatcc
    13321 attctgctcc ttgggctaga gctcttgcaa taaaaactct ctgaagctgt ccacccgata
    13381 gttcgctgat ctgtcttttg gcatattctt ccatccctac ttttttcaaa gcttgtcttg
    13441 cacgttcttt ttcttttttc ccaggtcttt gtccaattcg taaagatgga tatgttccta
    13501 aaagtacaac gcctaataca tcaattggaa aggaaagatc caattcactt cgctgttcca
    13561 cgtaggctat ttttttacgg actgagttta ccgactgtcc agaaaaggtg actttaccag
    13621 tagtagctgg tatcaactct agcaaagatt tcataaatgt tgattttcct gcaccgtttg
    13681 gtccgataat accggtaatt ttttgtggat ttatcgtcaa gttgatagtt ttcaaaacag
    13741 ttttcccttg ataagcggct gaaaggtctt gaattacaat ggccgtacgt tccaaatctt
    13801 acactccttt ttaggtttac ctaacttttt atttaaatat agtttaacta aaatggaaag
    13861 cattttcaag tagaatgatg aaaaagtttt tttcgaattt tcctcgcatt ttatgaaaat
    13921 tttctgtaga atcacatcaa gagttcaata aggctaacct aataatgaaa aacatgtgtt
    13981 gaaacgtttg attatttttt cttgttgact caacaacgaa aggagttttt gtatggaaga
    14041 agaaaagtta actcgaagtc ttagtgcccg tcatatccaa atgatcgcac taggtggaac
    14101 gatcggtgtc ggtctgttta tgggtgcctc ctcaaccata cgttggacag ggccctcagt
    14161 gatgggagcc tatgcgattg caggattctt tttgtatttg attatgcgtg ctttaggcga
    14221 aatgctttac gttgatcctt cgactggttc ttttgcaaat tacgcgagcg agtacatcca
    14281 tcctgtggct ggctacttga ccgcttggag taatattttt caatatattg tcgtaggaat
    14341 aagtgaagtg attgctgtag gatcttatat gaattattgg tggcctgatt tgccggcaat
    14401 tattcccgga atcattgtcg tcttgtttct tatgctggca aatcttattt ctgtcaaggc
    14461 gtttggcgaa ttagaatttt ggttttcgat catcaaagtc ataacgatca ttttgatgat
    14521 cattgcaggt cttggggtaa tcttatttgg atttggtaat catggtcagg cagtagggat
    14581 ttcaaatctt tggaaaaatg gtggattctt cactggaggc gtcaaaggat ttttctttgc
    14641 attatcgatc gttgttgctt cctatcaagg aatcgaactg atcggaatga ctgctggtga
    14701 agcagagaat cctaaaaaga cgatcattga agctgtccag tccactatcg gtcgaatctt
    14761 gattttttat attggtgcta tttttatcat tgtgagtatc tatccgtgga atcaattgag
    14821 tgagattggt tcaccttttg tacaaacttt ttctaaagtc ggcattacat ttgctgcagg
    14881 actgattaat tttgtcgtga ttacagcggc attatcaggt tgcaattcag ggattttcag
    14941 cgcaagtcgt atggtctata cacttgccat aaatggaaag atgtctaaaa aatttctgaa
    15001 actatctcgt cacggtgcgc ctttttatcc tgtcgtagca atctcaggtg gaatcttaat
    15061 tggtctgatc ttaaattatc ttctaccaat gttcatcaac cagtcagaaa atattttcgt
    15121 tttcgtatac agctcaagta ttttgcctgg tatggttcct tgggtagtga ttttgatcag
    15181 cgagattcgc ttcaaaaaga agcacgcaga taaaatgcat gatcatcctt ttaaaatgcc
    15241 actatctcct tatacgaatt atgtgacact tgctttttta gctatcgtat tgattttcat
    15301 gtttatcaat cctgaaacga gaatctcatt gattattgga ctcgttttct tgctttacat
    15361 gacgatccat tactttgtac gcgaaaaaag aaccggaaaa taaaaaaaga acgaagcttc
    15421 accttagtgg aagcttcgtt cttttttatt gcttttatca attcaatttt agcgtctcac
    15481 cgggagtcag gaaataattc tccatgctca tcccattcag cgacaagatc gtttctactg
    15541 gtacgccagt tcgttcggct atttgatttg gaccttctcc ttccaaaact acggttgtcg
    15601 cagcctgtga agtcgcgctg ttggtattag tttcagagga atctgttgtg tcttgtgttg
    15661 ttcgagcttg catttcagaa gcttctaccg actctgctgt ctcagaatca gaagatgttg
    15721 tgtcttgtgt gcttgttgac tctgcttgaa gagaggcgct agtctgcaaa taaatatcgg
    15781 aaatcttagc gacatgattc gtataattag ccgataattg attgatcaaa gtatctaagt
    15841 ctacaccgtc tttattttct gctgcctgat acgctgcacg taattttctg atcccttcgt
    15901 cggagattgc ttgaagctca cgtgcttttt ggttagcaac tgctgataaa ccagctattc
    15961 cctcttgatt tccctgaatt tctgtctggt attcttcaat caatgcaggc gtcttttctt
    16021 cgatcttttt cgaataatca tttacgattg cttgaagttg ctctggcaaa ccatttgctg
    16081 ttttttcttc agaagtttgt gtctcttttg ttttagttga tgactcactt gtttgtttcg
    16141 tctctgtttt ctttgtcgtt gtttccgtta tggtcgtact tttcgcttct gacgaatttt
    16201 ttccatgaaa atatagaccc gcaactcctc ctgctatgat caaaaacacg gcaactgctg
    16261 ccccaatcat gatcatccgc ttacgagctg cctgtttttg ctgtcttctt cgggtcatcc
    16321 gaacattttc tccccactca ttttcatcat acattttttt caccaccaat ttttatgtat
    16381 aatagcgtta tcaaacgctt catattctta ttgtagcaaa taattgtcgc tgtgcacatt
    16441 tttatctttg ttatttataa gaaaatttca ccagttgaga tgattccaag attgtccgtc
    16501 gatttctcct tgcagctgca ttgttcgttc gtctatctca gccatcagtt tctttatttc
    16561 atataagagc gcacggtctt gatattctga tttttcgctt aattcatcta attgttggat
    16621 cagccaatca tttgtcataa tgaagttcct ttcatttctt gcagtgtaaa ggtcaagtct
    16681 tcgatctgct cttttgcctc agtcagtgct tctacgatat atgcttgttt ttcagattct
    16741 tcttcctgca ttttctgatt ttcctgtact ctttgaataa accagtcaat ccgctgagtc
    16801 agcgatggtt tgccttccaa tgagagatac tgctgataag caattagctt ctcccaacgt
    16861 ttttcctggg ataaatacat aaattgtgct aaaacgaatg gcggaagata ggtcatatgg
    16921 aatttatttg cgattcgctg atacggcctc aaaaattcgg aaatcgtata ttcttctttt
    16981 cctccagctt ggtattcttt ttccgccaca cctgttgtca atacgattcc tagttctttc
    17041 ccttttaata catgtgctgc tcgttccaag acattatctt gccaaatttt taaatgagca
    17101 ggagaactat accagtaaaa cggaaactgg aaaatgatcc gatcatgctg ggccaagagc
    17161 tgtagttcag tctctatatc tatttttccg tctggataac ttgattccaa atgatgccaa
    17221 gtagctggta aaccagcaga agcttctttg aaaaattgct gatttaaaga ttcttcgatc
    17281 gttggatggc taatgatgat aagtgtacgc atcccttttc ctccttttta gtcttcgctt
    17341 tacagtgtag cataaccgcc acaagtttct tttgccgatg cttgtcattt taaccagact
    17401 aatcaggttg tccaagaaac tgcggtttgt ttttccaact gttttttcaa ggtatccaaa
    17461 gcaatattct taaaattttc gtttttcata cgtttacgat agttcgtagc cgtttctccg
    17521 gtactctttt tgaacattcg gctaaatacg actagactat tgaaccctac ttgataggca
    17581 atactttcca cggattcatc cgtcagagaa agaagaaacg cccctcgatt gatccgtacc
    17641 ccgatcaaat attccttgat actggtaccc atatgatttt tgaatactcg cgacaaatgg
    17701 ctccgattga ccgctaaatg ctgggcgatt tcctcaacag acaatttttc agcataatgt
    17761 gcctcgatgt atttgactgt ttcaacagct aaagaggaat gaaccttttg tacaccaccg
    17821 ctgacctttc cgccatcttt taaaaggact gataaaaaac ggtaggttaa tgctgttaac
    17881 tgtaattcat tttccaaggt ttcttccgta tctttcatgc attctaaaat aatgtcgata
    17941 tatttttgta tgtcagaaga gaccatcgtg tattggtctt ctctgaaaag cgactgccga
    18001 atgatttctt ctgcagcact cccaccaaat gaaagccagc aatacatcca cggatcttct
    18061 ccatctgata agtaaaacgt cgagtctcct ggacgaatca agaacagatc accttttttc
    18121 aattggaatt gttgattttt cacatgataa gatcctttgc cttccatcac gacatgcagg
    18181 atgtaatcat tgcgaatagc aggaccaaaa gaatgaaacg gcatcgtttt agagaaacca
    18241 caaaaatcaa aatacaattc tttttctact tgttgatgtt ccttttttaa aaaaatcgat
    18301 tgctccacgt ctatccctcc ttactccttt agtataatgc aacaaaaagt taaataaaag
    18361 tcacagaaat atattaaaaa ggaagcgatt tcttgttaag tttaagtcat taaaagatct
    18421 ttgttattcg ttgtaaccgg tttacttagt attatatatt gaacaggaga ggaatacaga
    18481 ttatgaaaag caaaatgatc caacgtgtgt cctacgcttt aggcgctttt ggacacgaca
    18541 cattctatgt tacattaagc acttatttta tggtattcgt gacaagccag atgttcgcag
    18601 gaacagataa ggcaacgaat gcaaaaatga ttgctacagt tacaagctta gttgtaggta
    18661 tccgcttagt tgaaattatt tttgatcctt tgattggtgg catcatcgat aatactcgta
    18721 caaaatacgg taaattcaaa ccatggttag ttatcggcgg cgttgttagt tccgtactct
    18781 tggtagcaat ctttaccaat ttctttggct tagctactca taatacgact ttatttatca
    18841 tattatttgc aatcgttttc atcttattgg atagttttta ttcatttaag gatatcgctt
    18901 tttggtcaat gattccagct ttgagtacgg aaacaaagga acgtgaaaaa tttgctacgt
    18961 ttgctcgttt cggctcttct ctaggtgcaa atggtactac tctagtcgtt gtccctatcg
    19021 ttactttctt tacctatctt gttactcata aacatattga aggcgcttca ggctggttct
    19081 ggttcggtgt gattgctgct gttatttcag gcggtactgc gattatcact gccttgggca
    19141 caaaagaagt cgatactgcg atccgtcagc aaaatgaaaa agctgggatc aaagatgtgt
    19201 tcaaagcagt tgctcaaaat gatcagttga tgtggcttgc ccttgcttat atcgcttatg
    19261 cgattgccaa tgtagcaaca actgccgtat tattctactt cttcaaatat gtacttggcc
    19321 aaccaactga attttggatc gttggtctag ttgctgcctt acttggttta gtagctgttc
    19381 cactattccc aatgcttaca cgcgtcatct ctcgtcgcta cgtttacctt ggagggatcg
    19441 caatgatgat ttcttcttac tttttcttta cgatcgcagg ttcaagtttg ccaatcgtta
    19501 tcatcgggct agtattgttc tacttccctc aacaattgat tttcttatcc gctttgatga
    19561 cgatcacaga ctctgttgaa tatggtcaat ggaaaaatgg tatccgtaac gaagctgtta
    19621 ctctatcaat tcgcccttta ctagataaaa tcgctggtgc tttgtctaac gggatcgtag
    19681 ggtttgtcgc tatcgcttct gggatgactg gtaatgctac tgctgctgat atcactgctc
    19741 atggcgtaac gactttcaaa gcttatgcat tctatgctcc tgctgctttg atgattttct
    19801 ccgctattat ttttgcttgg aagattacat tgacagagaa aaaacatgca caaatcgttg
    19861 agaaattgga aaacaaattg gctccagctg atacaatgga agatgaactt cacgatgcag
    19921 tagttccttc ccattaagaa aggatcttga aaatgaagat tacagaaaaa gattttggcc
    19981 aaggttatca cttgataacc ttggagaaca aaaacaagct agcactttct atctctgatt
    20041 taggtgctag aatcgtcagt ttaaaatcaa atgatcgaga attagttttg ggatttgaca
    20101 ccgctgaaga atatatcgaa aaagatccgt atatcggtgc ttctatcggt cgcaccgcag
    20161 ggagaatcga aaatggccgc ttttctctca atggaaaaac ttaccaatta gccacagatc
    20221 caaaaactgg acataatctg catggtggtg ctcctggatt tgaattaaaa aaatggtctt
    20281 atgtcatttt gaatggcgaa aatgaagctt ctgtcatttt tactactaca agtcccgacg
    20341 gagaacatgg ttttccaggt acaatggatg tggaaatccg ctatactttg acaaaagata
    20401 atatctggcg agtgacctct cgcggcacca gtgaccaaga tactttattc aatccgacaa
    20461 atcatgttta cttcaacttg acgggagatg cttctcagtc aatcgatcaa catgagcttt
    20521 ggctcaatag cgaagcttat gctcctttgc gaacagatag tattcctata ggggtaaaag
    20581 aaaatgctgc aggaagtgct ttcgattttc aaatacctaa aaaattagcg tccgtttttg
    20641 ctagtgattt ggatcaaaaa aatcttgttg acggaatcga tcatccattt ttcttaaaag
    20701 aaaccggctt gggtaaagaa gccgctcgct tgactagccc cgataaaaga atccaagtag
    20761 atattgctac agatgcttct agtgtggtta ttttcactgc aaatttcggc acagaaacac
    20821 cagaaatgcg caaccgaaaa ctggcacatc acggtggcat cacatttgag actcaaacag
    20881 ctccaggtgc agagcgcttc tcagcatttg gttcgattca tttaaaagcc ggatcagtat
    20941 ttgaaacagt aacagaattc aaaatcaaaa caagaaagga ataactcatc atggaaatca
    21001 aaagaagctt aaacacaaaa tttgccgaaa cattcggacc taaaaaaact acacaatact
    21061 tctcaccagg acgcatcaat ttgattggtg aacacacaga ttacaatgga ggccatgtct
    21121 tccccgcttc catcacttat ggaacgcaag gtgtagcagc acctcgagac gataataaaa
    21181 tattagttta ttccacaaac tttgacgata tcggtgtcat tagttttact ttagatgagc
    21241 tagaatatga taaaaaagca aactgggcaa attacgtaaa aggaatggtc cttaaattaa
    21301 aagaagctgg acactcaatc gatcatgggt ttgagttatt agtggaagga acaatcccta
    21361 atggtgcagg actttccagt agcgcttcat tagaattatt agtaggtgtt gtattagaag
    21421 atctgtttga tttaaaaaca gatcgcttgg aactagtcca aacaggtaaa aaagtagaaa
    21481 atgaattcat cggtgtcaat tcaggtatca tggatcagtt tgccatcggc ttcggtgagc
    21541 tagatcatgc aatcttatta gatacaaata cgctgaaata cgaaatggtt ccagtgaaac
    21601 tagatggtta tgcaatcgtc atcatgaata cgaataagcg gcgggaattg gcagattcaa
    21661 aatacaatga acgccgtagc gaatgcgaag aagccttggc acgtttgcaa aaaactttgc
    21721 ctatctcttc tttaggagac ttagatgaag aagaatttga atcaactatt gaccaaatcg
    21781 gcgatgatac attgatacgc agagctcgcc atgccgtttc tgaaaatcag cggactttga
    21841 aggcaaaagc tgaattagaa gctgggaact tagaagcatt tggtcaactg ttaaatgatt
    21901 ctcaccactc tcttcgctat gattatgaag taactgggat cgaattagat acactagtag
    21961 atgctgctca aaaacaagaa ggtgtcttag gtgcacgaat gacaggagct ggatttggtg
    22021 gctgtgcgat tgctcttgtc aaagaagaaa atatacctgc cttcaaaaac aatgtctatg
    22081 atgaatacat gaaagttgtc ggctatgctc cggaatttta tgttgcacac attggaaatg
    22141 ggacaacaaa gatcgatcca gaagctgttc atgtttgata aaaaaatcaa cgatctcagc
    22201 taaaaacaaa tagataaaaa taacctctca gcaatttcca aatgtgagcc ttttgctcgt
    22261 atttgaaaat tgctgttttt tattgacacg gaaagagaac gtgtgttcta attgtgttga
    22321 agaggtgatt gttatgtggg cgaatcaaaa tccggtattt gtttatgaaa aagaaccttc
    22381 aagagatatt ttatgtattg actgcaaatc tttttacgcc tccgtagagt gcgttgaaaa
    22441 ggatcttgat ccccttacaa ctaaattagt agtcatgtcc tatccgtccg attcgacaga
    22501 aacacggggt agcggattaa tcttggcttc cagtcctgca gcaaaaaaag cttacggcat
    22561 caccaatatc agccgtgcca gagatcttcc cttcccctat ccaagtgatt tatatattgt
    22621 tgccccaagg atggcctatt atatggaaaa gaacagagaa atcaattcta tctataaaaa
    22681 atatgcagac gaagcgaacc atcatgtcta ttccgtcgat gaaagcttcc ttgatgtaac
    22741 aaatagcatg gcactctttg gtaaaacaaa tgcgtacgac atggctaaac tgatccataa
    22801 agatgtgttt gagcagaccg gaatctacac gactatagga attggcgata acccgctact
    22861 tgctaaacta gccttagaca atggctcaaa agacggaaag caaatgtttg ctgaatggcg
    22921 ttatgaagat gtaccagaaa agttatggaa aatctcagat atcactgact tttggggaat
    22981 cggcaaacga acagcaaaac gtctgaaaca aatgggtata cattctgttt atgatttagc
    23041 tcacgcggat tattatcact tgaaaagcaa gctaggggtc atcggtactc agctttatgc
    23101 ccatgcttgg ggcatcgatc gaagtttttt gggacaagaa tatacaccaa aatcaaaaag
    23161 tatcggaaat agtcaaatcc tagatagaga ttatacaaga cgagaagaaa tcgagatcgt
    23221 tatcaaagaa atggccgacc aagtcggcac tcgcttgaga cgatctgcag caaaaacaca
    23281 agtagtcagc ttatgggtag gatactcttt aggctatctt gatccaaatg gcaagaccgg
    23341 gtttcaccag caaatgaaaa tcgaagcgac aaatgctagc agagatctag cagatgcttt
    23401 attgaccatt ttccaccagc attaccacta ccaggatatt cggcgtgtag gcgtgaactg
    23461 ttccgacctc gtatacgcga caggtttaca gcttaacctt tttgaagatc ctgaaaagca
    23521 gataaatgaa gcgaaagttg attttgttgt cgatacgatt agaaaaaaat acggctttca
    23581 atcaatcatc catgcgcata gtctcttgca aggaggacgc gccatcgcac gtagttctct
    23641 cgttggcggg catgcaggtg gtatgagtgg attagaaggt ggaaaagatg agacggacag
    23701 caaaaaaatt cattgactat aacgagtatc gagatcggcc atttggatta aaatggggga
    23761 ctgcttttgc gatggaagaa ctagtcaacg gtatcaaaaa aatgaagaag aagcacgcaa
    23821 acagcctctt cctaaacaac aaatgacatt gcaagaaatc gatagtatac tgacagaagc
    23881 ctttttatct cgtaaagcag taatcattca gctcaattta aaagatgaat ttggaagact
    23941 cttggatgag gtcgaagggc acttcattgg tgaagcctat gaagattact ttatgattga
    24001 ccatcagccg atattgtggg aagacgtacg gtatattgag ttaaaggaaa caaaaaaatg
    24061 gtttgtgaca tgagaggttg tgacagaagt gatcaacttc aaaaaataag aaaggatttt
    24121 tcgaaaattg cttcttaaat ttttgtggaa ttttggctta tttttcgaag aagcaacttc
    24181 tggaacaacg tatattagat atcagaggtt gtgaaaaagt cgcttagttt tgagtaacaa
    24241 gccaaggcgc tgatttcaca acctctgtct atctatccat ctattcggta agattcatgc
    24301 atgacgtctt ctttatttag tatgtagagc cctttttctt ctgaccattc aacataaatc
    24361 agctgtttta catctgcata gccttctttc ttcaagttct ccataagcca tgcttcagtc
    24421 aattgattgg actgaagcac tttatgctga atttgccctt catctacaag caggatcgat
    24481 aaagctttgt cttcatctga ttttttcaat acactcattt gaccggcatt ctctaggata
    24541 acatgtttgg cattttcaag aaaaaagcat tcttgctgtc ttaagattgc tcgcaactgc
    24601 tccatctcga tatggttatt tgtcaactct gtcatgttga tgacgccgtc tttgattaga
    24661 acagatggct cgcctttgac ccaacgattg accttttcat ttttttggac gatacgttcg
    24721 ataccataaa tcattactgc ccaaagcgca atggcaaata ggacatgccc tacatggaca
    24781 ttgtcatcat aggttgattc ttctaagatc ccacctaaaa caagcgtata gactaaatca
    24841 aacggtgtga tttctgacat ggatttcttc ccaagcaaac gtaccactaa taataaaccg
    24901 atcaacccga acaccagttt cattgtaatt gaaaaaatca ttttttctcc ccctaactat
    24961 ctgttaatta aattatatat gctttctcac gaacacgcat ggaatataca aggaagaaat
    25021 gtatcctttt actaaaaaaa ggactgtgac actgtagtga cccccaaaag ttagactttt
    25081 ttggagtgga gaaatccact cctttttttt atgctctaaa atgatatttt tacacaaccg
    25141 ttacggttgt tttacgaaat tggacgagac tttgccagtt taatttctgt tttatccgtt
    25201 cattattgta gtaatagata tagctatcga tggctgattt taattcctcg aaacagttat
    25261 aaactttccc gtgaaaaatc tcttgtttta ataagccaaa aaaattctcc ataagtgaat
    25321 tatctaagca gttccctttc cgagacatgc tttgaaagat tttgtactcc ttcaatttgt
    25381 ttctataagc tttcatttga tacgcccaac cttgatctga gtgaaacgta cgacgatagg
    25441 gacaatcgtt agtggtctgg atagcttcct ccaaaccttc cattaccgct aatgcattgg
    25501 gcttttcaga gatacgatag gataaaatct cactattgaa catatccata aaaggatcta
    25561 gatacaattt cttttgacgg ataatgcctt tggcatccac ttcatggtat ttaaattcag
    25621 ttgtatccgt cgtgattttc tgatggcaga tactggtgta gaaacgacga tggatccgat
    25681 ttttggctac tgctccaact tttcctcgat aagaattgta gcgacgtgat ttacgcgtgt
    25741 atgccgttac ttttattcct agcttcttga tcaagcgctg aactttcttt ttattgatag
    25801 agaaaccgcg gtttcttagt tcattggtca tccgtaaaca gccataatcc ttgtgcttct
    25861 cccgaatttt aagcatttcc gcttcaatct cttgatctgg atttttacgg tccaatcgcc
    25921 tttgccatcc aaataatcat gaacgatctt taatttaagt tcaaaagtat atttaaccat
    25981 aaaaaatacc gacctccaaa agttagattt tttggtctaa cttttggggg tcggtacaca
    26041 aatcgtgtca cagtcccttt tttgaaaata aacggtgttc aaaagcttgc atctgcggta
    26101 ataagtccag ccaagttaaa aacataagaa gctgttttta cttggctgtt cttattactt
    26161 gatgcaaggc agctttttca caacctcttt tcaaatattt cgttttctta ttctacaaat
    26221 ggttcttctc ctaacgcttg ttgagcggct agattcaaca tgctccattg tcggtcaaag
    26281 cctggctgga agaagaagtc agcttctgct agttcttcta aagtcagttt gttttggatc
    26341 gctagtgcca atacatttcc ttgacctgta acatcatagg tagataatac tgctcctcct
    26401 agcaattgat gggtcattgg atccgagaat aattggatgg acacttttgg atttccttgt
    26461 tcttctggta catattttgg tcgtaacgta tcttcataat aagacactcg tacatctact
    26521 cctgcttttg ctgctgtaaa gctattcaat ccgcttgctg caaaatgata gtcaaagaca
    26581 cttaatgcag aggaacctac gactccgccg aacggtttgt ttggtacttc ttcaaaaaga
    26641 tgttttacta cataacgtgc ttctctacgt gcaacagtcg ctaaagcgat cggcattttt
    26701 ttgcgtgctg ggatagaata agcaagtgta gcatctccta ctgcatacac atctggaaga
    26761 ttcgtttgca agtattcatt tgtttggatc cagccacgtt catctaagtc gacgatccct
    26821 tttaaccatt ctgtatttgc cttcacaccg gcagcttgaa tgactagatc tgctgggatt
    26881 tctttttcac ttgttttgat tgcctcaact tttccgttac cagtaaaagc ttcgattttt
    26941 gcatttgtca aaacttcaat accgttttca tttaggtgtt gttctaaaat atctgtcatc
    27001 tcagcatcta aataagtgcc taaaggtcta tcgatcacat caagcaatac gacttctttc
    27061 ccagcttttc ggcttgcttc tgctgcttcg atcccaatgt aacccgcacc tacgacagcg
    27121 atttttttaa tagccggatc atttaatttt tctttgattt tggttgccca attgtatcca
    27181 cgcatcaagt agacattttc tagatctgct cctggtactg gcagattgtt tggtttgaca
    27241 ccagaactca aaatcaattt gtcataagga tattcttttg tttcgttatc tgatgcgcta
    27301 gtaaccgtta ctgttttttt atcggcatcg atcgttttta cttcgtgatt atttaaaata
    27361 tgaacattgg attgcggaaa gttttctggt ctgaaattac gtacatcatt tacatctgtt
    27421 accttgtctt ctaaatacag ctccatacca catgacatga aggaaatata gtctcctgct
    27481 tcaaatagcg tgatatctac attttcaccg tatcgtgtca atagttccaa gatcgattga
    27541 tgccctccat gagatgcacc tacaatgaca actttgattt tttccattga tgaaacctcc
    27601 ttgaatattc ttttaaaatc attctaaaca atttaaactt aacattacat tagttatgaa
    27661 tcaaaagaaa cgcgttcatt tgaactaaat ttaaaaaaca atcgtctcct tgcagaatat
    27721 accgcaaaat taacgattgt ttttttgata aaatctatga atcactgttc tgttaaaaag
    27781 tctttgatcc gtttgcaggc ctcatgtaat ttttccatgc tgctagcata agaaatccgg
    27841 atataacctt ctccttctgg gccaaatgca attcctggga tacacgcaac ttttgcctgt
    27901 tccgctaatt ctacacaaaa ctgccaagag tcagtttgaa tggcagctgg gagtttgcaa
    27961 aacaagtaaa atgcaccgtt tggctgggtc acttcaaatc ctaaaggcgc caattgctgg
    28021 accagatagt ctcttcgtgt ttgatattgc tctttcatat tctcgctatc tttcacccca
    28081 tttattagcg cttcagccgc agctttttgc gacatcgttg tagcggcagt caccagatat
    28141 tgatggactt taattagttc gtcaataagg gctttttgag caaaaataaa gcccactcgc
    28201 caaccagtca tcgcatgtga cttggataac ccgcttatca cgattgtttg ttctggaaga
    28261 taagtagcta tggacatatg cgttccacta taagtcaatt cagcatatac ttcatcactt
    28321 ataacaaata ccggatattt ttttaaaacc tcagcgattg ctttcaattg ttttgcagac
    28381 aatgtcgtcc cagtaggatt gttaggatag tttaaaatga ctgctttgac agctgatcca
    28441 tattgttcaa atgctcgttc aaattgttcc ggctgacaga caaaccctgt gtcagaagta
    28501 tctatcggga tcaattcagc accagctagt tccactaatg gctgatatcc tgaataagca
    28561 ggcgctggaa taagaacctt gtctccttct tccaaaacag ataacaacgc agaggcaatc
    28621 gcttccgttg caccaactgt cgtcaaaact tccgtttgcg gatcataagt taatccataa
    28681 cgctgttgct gaaatataca agccgcttcc cgcagttcct ctaatcctct cattccggta
    28741 tagtgagaaa agtcttcttc aatcgctgct attcctgctt gcttgacatg ttcaggagtt
    28801 ggaaaatccg gttctcccag ggtgagtttg atcacatctg gtatcgacga tatttgctga
    28861 tcgaattgtc gtatttttga tacttctatt ctagaaagcc taggactaaa tcgattggat
    28921 aaattcatca ttatttactc gctcctcttt tgaactgcta tcgattttta caagaagatt
    28981 ttctgtaaaa agaatcgttt tgtaccattc tacaccattt tctaaaacat ccatatcaaa
    29041 atcgaacgtc ggatcatgta aagcaggggt atcaccgaca cctaaaaaga aaaatacaca
    29101 tggatattgt tgcgtatata tgccaaaatc ttcggcttga agaactggag catctaattc
    29161 atgtagtttg tttgaatcta acagtgctgc atataagcct ctatggttga ttacagctgg
    29221 atagccgtca ttatagcgaa aagaaatagt agctgtagag tgaaactgtt ctgctaaatg
    29281 gtctaatccc ctcttcaaat aattttgcat atctgaactg taagaacgga tacttccgga
    29341 tacaataact tctccagcta aaacatttcg gatcgttcca ccttggattt ggccaaattt
    29401 cattagatga ttccactctg ccggtaattg ccggtcaaaa tcataaacat tcttcaaaaa
    29461 tcgtacagct gcctccagac tatcgattcc tttttcacta gaagcaatat gtgcagactg
    29521 gcctttaatg ataatgtctg tttcactgct ttgtgccatc aaaggtcctg gtcgagagaa
    29581 aacttctccc ttagctagtc caggccatag atgaaagcca aatattgctt gtacttcata
    29641 tttatccaac aatcctgact gaataacgct ttgtgcgcca ccggaaattt cttctgatgg
    29701 ctgatagatc agtactacat tataaataag atcctcaatg tgtttagtta taaagtcagt
    29761 caaccctaaa agcatcgcca tatgtccgtc atgaccacat gcatgcatat aaccttcatg
    29821 cttagaagca aaagagagat tcgtttcttc tttgactggc agtgcatcga tatctgttcg
    29881 aaaagcaatc gtttcttctt gctgattatc aaaataaagg agtagtcctg tttcgccgat
    29941 ttcatggata acggcctcgc tgttttttac ttgttcatat aaatattttt ttgtcttgaa
    30001 ttcatgaaac ccgatttcag gaatttgatg gagtgccatt cgatattctt tcagcatccg
    30061 tattcaccat cccttcatag atacccttca ctactgttcc atattgatta ttcggtacac
    30121 cgatgatcag attcaactcc tgtgctcctt gtgataagat cgatgtgcga atttctaatt
    30181 tgttcaatat cgataacact ttcccagata atccaatcaa ttctttatgc ggacccccaa
    30241 cgacagagat caaagctaag tcttcgatca cgacgatttc ttccacgcca agtgtttctt
    30301 ttaattcttt cgtgatgaga aataacttat cggcaatcgc ttctgctgag acgatcactc
    30361 cgatattgtc gatccctgaa ggaatatgtt cgattgatat ctcatgttta gcaaaaatgc
    30421 tcattgcttt ccagataaac ccgatttcat cggacatatg acgtttgaat aaagtgatgg
    30481 aaagaaaatc cttgcgtcca gctattcctg tcagtccatt ttccttttct atttcgtgat
    30541 tcgatatttt tgtcccttga gcgaaaggat cattggtatt ttttatttgg atggggatat
    30601 cagcctcttg aactgggaaa acagctgctt catgaagaac gttagccccc atataagcca
    30661 tctctctcag ttctctaaaa gagatttcct cgatgatttt aggatgatcg atgattcgcg
    30721 gatcagccat catgattcct gaaacatccg tccaattctc ataactttcc gcttgcaaca
    30781 tcttcgccag tatcgcgccg gtaatgtcgc ttcccccacg gcccaataat ttttcttttc
    30841 ctgcagggtt cgccccgtaa aaccctggaa caaccatttt cggatatctt ttaaatgctt
    30901 ttgtgatttc ctgtgctgtt ttttcctgat cgattttccc atcatagtca aagaaaatca
    30961 ggtcttttgc gtcaataaac tggtaaccaa gatactcagc catcagttga gcagtcagat
    31021 attcacctct acttactaaa taatcttcag ttatcttttc gtcttccagt tgtttctgta
    31081 tgcgtgctag ttcatcttca ataggtaact gcagggcaag aacatctctt acttgaatga
    31141 aacgatcaca aatccttttc caaaggggtg tccaatcaac atgatgctga aggtaagcat
    31201 aaatcaaata aagtaagtct gttactttgt catcatctga cgtacgtttg cctaaagcag
    31261 aaacaacgat cacttggcga ttgggatctg aaagaacaat tgtacggact tttttgaatt
    31321 gctcttcatg agacatcgat gttccgccga atttcgctac tttcagcgta ttactcatct
    31381 tgccacctcc gctattttct gcattaaagc tgcagcaatc tgtacggcat tcgcagcggc
    31441 tcctttgcgt atgttatcgg cagtcgtata gaacaacaat ccgttctcta aagaagtgtc
    31501 ttttctgatc ctcccaacat aaaccatatc tgttcctcta gcaagaatgc tcgtcggata
    31561 tttatgtgct gctagatcat cttctaattg aatccctgga aactggctga gacactctct
    31621 aatttcttcc gtcgtaaact ctttttgcag ttgaactgcc acagagactc catgtccatt
    31681 ttcgattggc acacgtacgc aggttgctga tactggcaaa gcaggctgat gcagaatctt
    31741 acgggtctca tttatcattt tctgttcttc ttttgtatac ccattttcca aaggctgatc
    31801 gatttccgga atcaccgttt ggctaatatt ataaggatac aaaactggtt cctcgtcatt
    31861 ttgcgtacga tgaagatctt caatgccttt ttgcccggaa ccagaaactg cttgataggt
    31921 cgaataattg actcgctgga taccaaaggc ttcttgtaaa gctttaagcg gaagtaccgc
    31981 ttgaatggtt gaacaatttg gatttgcaat cagccgattc aatgtatagt cttccagatt
    32041 gacctctgga acgattaatg gaatatccga atcttcccgc catgctgagg aattatctat
    32101 gacaaatagt ccctgacttc gtgcgattgg cgcaaactct ttggatacag aagcacctgc
    32161 agaaaatagc gctaaatcat atccttcaaa tgaagtttct gtcaattcct gtacagtgtg
    32221 tttctttttc ttgaatacac aaactttacc ggctgaacgt tttgaagcta ataatttcaa
    32281 tcgtcctact ggaaaatcat attcttctaa cactttgagc atcgtttggc cgactaatcc
    32341 ggttgccccc acaatacagg tatctatttc gcgcattttt ctccatctcc tctataattc
    32401 gcgtaacgca gcaatcaatg ctgtattttc ttttgtctga tcatcactta tttttaatac
    32461 acgtgcaggt attccaccga caacagtttc tgctgccaca tcttctaaaa ccactgctcc
    32521 tgctgccacg actgcatctt ttccgatatg gacaccttca acaatcactg cattcgcacc
    32581 taccagtacg ccgtcttcta cgataaccgg tttggccgat gctggttcga tcacacctgc
    32641 taagacagct cctgcaccaa tatggcagtt tttgcccact gtcgctcgtc cacctaagac
    32701 agcacccata tcaatcatcg tgttttcacc gattactgca ccaatattga taatcgctcc
    32761 catcatgatc acggcattgt tgccgattga cacttgatct ctgataatag cacctggttc
    32821 gatacgagca ttaatttttt taatatctag caaaggaact gcgctgtatc ttgcagcagt
    32881 ttcgatttcg atttcaatga ttttttctga ttcagcttct aaaaccggag caatcgtctc
    32941 atagtcacca aaaacaacga agctgcttcc ttcaccaaaa actttacttt ctttaaattc
    33001 gattggctcg gttacattca gatagacttt cacaggcgtc tttttagatg ccgtttgaat
    33061 gtagcggatg atttcttgag cttccacgtt ttttacaccc ctttgtccat taataaatct
    33121 tctaatttgt aataacctgg tgactgatct ttcaaccagt ccgctgcttc tactgcgcct
    33181 gcagcaaaga ttcgattaga aaaagattca tgtttgatcg taaatatttc atcagtagca
    33241 gcaaacaata catcatgttc accaggtaaa gaacctgcac gaatactgtg tacaccaatt
    33301 tggttttctt ctcttttttt cccttgccag ttgtatacgg gctgcagctt ttgcacttct
    33361 tggattgttt gaagcagcat atttgcagta ccagatggtg catctttttt acgactatga
    33421 tgtttttcaa tcagttcgat ctgccagcct tgcaacattg cagctgcttg cttgattagt
    33481 tgattcatca ccatgatgcc gaacgaaaaa ttagcactat acatcacagg tacatgtttg
    33541 gcatgttctt ttatttcttg gaactgtgat tgtgtataac ctgtcgtgcc aatgactaac
    33601 ggaagttgat atgataagct atacgaaagg attttctcta aattatctgg atgagaaaaa
    33661 tcaataagca gttctggcag ttccgtaaaa gcaagcgtag ttgcttcttt aggtgccgtc
    33721 cgtaaaagaa ggaccgtatc tcctctttct tgtgcaactt cttcgactct atttcccatc
    33781 tgtccactgc caatcagtcc gattttcatt tttcaaccgt cctttctttt aacaaaagct
    33841 gagctaattg tttctttttc tcttttgaaa gagaaactaa aggcaggcgt agaggtccgg
    33901 aaggtaagtc taataatgac atggctgctt tgacaggaat aggattggtc tcactgaaca
    33961 aggcatggat cagttcaagt gcatttaatt gcttttcttt tgcttgctgc catcttccgt
    34021 cctgcgtatc ttttactaat tcatggacta ttttaggttg gatattcgcc catacactta
    34081 ttacaccgct tcctcctaca ctcattactg gtaggatcaa atcatcattt ccactgtaaa
    34141 ggaagaattc ttctccaatc aaccgagcgg catccatcac ataagccata tctcctgagg
    34201 cttctttcaa accaatgata ttaggatgtt ctgctaaatt tactaataca tggattggaa
    34261 tcgacatgcc tgttctagaa ggaacattat acaaaataag cggaatcggt gaggcttctg
    34321 caattgctgt aaaatgagca gctagtcctg catcacttgt tttgttgtag taaggggtga
    34381 tgaccaaaag tgcgtctgcc cccaaagaag caaaatgctt cgctttttca atcgtttctt
    34441 tcgtattatt cgttccagct cctgcaatca ccggcacacg gccagccact ttctttactg
    34501 tcagttgaag gatctgctcc tcctcagatt gtgtgagcgt agaagattct cctgttgtac
    34561 ctaaaactaa taatccatct gtttgttcat ctaaatggaa ttggatcaat ttttccaaac
    34621 cagcataatc tactgatccc tcttcattca tcggcgtgat cagcgccacg atcgaacctt
    34681 ttatcatctt cattcctcca atattcttgt ccattcatga actgctgggc cagccatttg
    34741 tatcgcatcc tcaccagaga tcatcaagtc tccttgttcc aagtgaacaa ctacctgatc
    34801 tgctgaaatt ttcccagttt ccttagcaac cacataagag gcacagcaac ctgtaccgca
    34861 agcaagtgtc caacctactc ctctttcata ggtacggacg atcaattctt gttcattgac
    34921 tacttctaca aagttgacat tggttttttc tttgaacaaa ggatgatgac agatcagttc
    34981 acctcttttt ctccagactt cctcacgcgc attttcaaca aaaacaacgg tatgaatcgt
    35041 tcctaaaaat aaactagtga tcgttacttt ttcaccattg atctctattt cctggttttt
    35101 tattggataa gtttgattag ctttgatttt ttccggagaa tcatctggca ctcccatatc
    35161 tacgctgcaa taaaaaggtg agggatccaa caccgtaatt tttcttgtgc ctgctaatgt
    35221 ctctacgttg aattcctgtt cattcatcat gttctgatca tttacgtatc gagcaaaaca
    35281 gcgaatgcca tttccgcaca tcggcgcgcg gctgccatct ttgttgtaat agatcatttc
    35341 caacggatcg atttttacgg cgatcaatcc gtctatatca tatttttctt ttgtgcataa
    35401 agaagcggct aattgactat aatctgtgtc ttctgcgtaa tctaataaga taaaatcatt
    35461 tccgcagcca ttatatttat gaaggatcat aggaaacttc cccccttagt agatcagaaa
    35521 atgcttgtct gcgaacaatc agtcttgatt ggccattatt gacaaaaaca actgctggtc
    35581 gtgtcgctcg attgtagttg ctgctcatcg agtatccata agctcccgtg gaataaacag
    35641 ctaaaagatc acccgattct gctttcggca aataagcttc tttaattacc acatcgcctg
    35701 attcacacat ttttcctgca atcgtcactt tctctgtttt ttcttccgac agttttgctg
    35761 ctaaatcaca atcgtattct gcctgataca gagctggacg gatattatct gtcatcccgc
    35821 catctacaaa gtaatatttt ttatgtggtg tctttttgat gaaaccaatc gtgtatagtg
    35881 ttgtaccagc ttctccaaca atacttctac ccggttcgat cagtaattga cgaatggtca
    35941 gttttcgttt ttccaaagct tcttccgtat attcaatcag tttttttagt gcctcttcga
    36001 ctgggatcgg ctgatcattt tgtgtataac gaatcccaaa ccctccgcca agattcaagg
    36061 aaagaggttg gtcaaaatcg gttaagtaat tcgtcaattt gtcgatttca gctaaccaag
    36121 cagtaacatc aaaaatttgt gacccgatat gagcatgaaa tccttctaac tctagatagc
    36181 tgctttcttt tatcaactga agggcttgtt ggcactcttt actttcatag ctcatgccga
    36241 attttgaatc aatatgcgca gtgacgatat attcatgagt atgtgcttct actccgacat
    36301 tcaaccgaag catgatacag atttttttta aatagcgttg gcttaattct gctaataatt
    36361 caacttccat caaattatcg gcaacaatat gcaacaaatc attttcaagt gcatagatca
    36421 gttcctctgg cgtcttgttg ttaccatgga agtagatagt atctctagga aaatcagctt
    36481 gcaaagcggt atagatttcc ccaccactga caacatctag cccgaatcca tattcacgaa
    36541 ctaaatgcag catctcaatc gtttggaatg ctttagaggc gtaaagcact tttgtatcaa
    36601 aacgtttcga tacaaagcct cgcttgaatg acagcatcgt ttgtctcatc ttttcttcat
    36661 catacacata cagaggtgtc ttatactttt ctgccaatgt gcttgctgtg actccgccaa
    36721 ttatcaattc tgtcattttt tcattcctct tttcactttt tttccgtttt tattggaatt
    36781 tcatttgata aagatttgaa ttttattgga ataatattaa acaaaatttt ctgaattgtc
    36841 tagtatattt cgaaatattt ttttaaaaat aagaataaaa atggttataa aaacaaaata
    36901 cccgaactat tagaagctat ttatacataa aaacataaat tcaacactat ttagtgatga
    36961 aaaaatattt tcgcttcaat atagttcgga atagttcgga tattttcaat tttatgaatc
    37021 atttcaattt cttcataaat aagtgcagtt ttttctttct ctagcttttg ccattcatct
    37081 ttcaaaatat aaataaaatc aaatactttt ttatttttca atttgctgat tccacaaaaa
    37141 acctcttgaa aggcagatcc gatgatctgc ctttcaagag gtcaagctct gttttcaaat
    37201 tcttatcaat ccgttagcga attattttga cgcacgtttt acataagaac cttctgctgt
    37261 attgatttcc aacaattcat ctgtttcgat gaagtcagga acattgacta ctaagccagt
    37321 ttccattgtc gctggcttac ctgaaccagt gactgttgca cctttgatgg aaggttgtgt
    37381 ttccacaaca cgtaatacga cagttgttgg taattgaacg ccgatgactt cgctaccgaa
    37441 aaattggatt tttacttcca tgttttctag gatatatttc atttcttctt ctactgtttc
    37501 tacaggaatt tcatattgct catatgtttc caaatccatg aagaaagctg tatcatccat
    37561 cgtgtacaaa tattgtacag gttttgtgtc gatatgtgct ttttcaaatt tttcttctgg
    37621 tctgaacgtt gtgtcgtatg ttgcacctga acggacatct ttcagtttca tacgcataac
    37681 tgtatttcct ttaccaggtt tatggtggct tgcatccaga actttaatca gtttgccgtc
    37741 ttgtacgaaa gtcataccgg ctcttaaatc acttgctgag atcattattt ttgctccttc
    37801 ttttctttat cataatcaac tttattgtat cagacaaccg gccagaaaac tagagtattc
    37861 tctatctttt aaggtctcat gcctatttgt cagaaaaata aacacgggta aacgatgcta
    37921 tcgaaatatt tttttctttc aagcctttga cttttatttt ttttcatgct atcgttaata
    37981 aaaattttac ttggagggat acacatgaca gtcagcaacc aaaaacaatt gaatcgttgc
    38041 tgttgtatgg tgcataaaag cagcatacta tttgtcatgt ctattaattg cccttcatag
    38101 aatgagtacc aggtaactta tctttttatc tactcaattt ttctctatgt ctttcaagga
    38161 gctgatttaa tagtcagctc ctttttttat tatctttttt taggaggccc acatgattat
    38221 ctcgacaatt acagaagcta ttggttccac accgctttat cgctttgaca atcagcacta
    38281 ttctatgcct aaaggttctg ctatttatgc aaaactagaa tatttaaatc ctggaggaag
    38341 tatcaaagat agattgggca gttatttgat caaagaagga tttgcccaag gaaaaatcaa
    38401 tgaaaaaacg acgatcatcg aaccaactgc cggaaataca ggaattggga tcgctctggc
    38461 cgcactcaca tacaaattaa gaacggtttt tgttgttcca gagaagttta gcttagaaaa
    38521 acaacaattg atgaaagcat tgggagcaaa gatcatccat tctcctagtg agcaaggaat
    38581 catcggtgcc atcagcaaaa gtaaaaaact tgcagaggag atatcaaaca gctatctgcc
    38641 tcttcaattt gaaaataaag ataatcctgc tgcttactat catacgttag ggccagaaat
    38701 ctttcatgaa atcaaagaaa atatccatag ttttgtagca ggaattggga gtggtggaac
    38761 ctttgctgga acttctacct ttttgaaaga aaaatatccc gacattcgaa taatcggtgt
    38821 agaaccagag ggctctgtgt taaatggtgg tgatccagcc cctcacgaaa ttgagggtat
    38881 cggtgtagaa ttcattccgc cgtttctttc tcccctttca atcaatcaga tcgagacaat
    38941 ctctgatgta gaagggttta actatactag gcagttagca cgagaacaag gactattagt
    39001 tggaagttcg agtggtgcgg cttttgcagc agcattaaga gaaattcgtc gtttaccacc
    39061 tggtcatcgt gtcgttacga tttttccaga cgcagcagac cgctatttat caaaaaacat
    39121 ttacttatag gaggaaagaa acatgcacat tcaaacaaaa ttgatccacg gaggcatcag
    39181 tgaagatccc acaacaggag ctgtcagtgt acctatttat caaacatcca cttatcggca
    39241 agatggcgtc ggccagccta aacaatatga atattcaaga tctggtaatc ctactcgttt
    39301 tgcattggaa gaactgattg ctgatttgga aggcggtgtt cgaggattcg ctttttcttc
    39361 tggtctttct gggattcatg ccgttttttc tctttttcaa gctggcgatc atatcttatt
    39421 aggagatgat gtctatggag gaacattccg tctatttgac aaagttctta ctaaaaatgg
    39481 tctcgagtac acgatcatag atacgagtaa tcttgataaa atagaacaat ccatcaaacc
    39541 caatacaaaa gcactttatc ttgaaacacc tagcaatccg cttctaaaga ttactgattt
    39601 agaaaaaagt gccactctgg ctcatcaaca tggattgata gttattgctg acaatacatt
    39661 tgctactcct tattttcaaa gacctttaga tctcggttct gatatcgttg tccatagcgg
    39721 taccaaatat ctaggcggac acagcgatgt agtagctggt ttagtgactt ctaaccataa
    39781 agatctagcc gatcagatcg gattttacca aaatgctatc ggagccgtac ttggtcccca
    39841 agatagctgg ttacttcagc gcggaatcaa gacactaagt gttcgtatgg aggaacatca
    39901 aaaaaatgct tttgtggtag ctgattttct attttctcat ccagcagtag aaaaggtcta
    39961 ctatccagga ttacccgatc atgaactcca tggagttgct aagcagcaga tgagcggctt
    40021 tagcggaatg atttctttta ctttaaaaaa tgaagaatct gctattccat ttgttgaatc
    40081 actccaacta tttactttag cagaaagttt aggtggcgta gaaagtttag tggaaattcc
    40141 ttctgtcatg actcatgcgt ctattccaaa agaaaaacga gaagaggctg gcataaagga
    40201 cggcttgatc cgtctttctg taggaattga gtatggtcag gatctcataa acgatttagc
    40261 tcaggcattt gacagaatca agaactagaa gtcccaataa acgacttagc agaaaaatct
    40321 aaaaaatatt tcagattgct acaccttgga aacgataagt gttagaatca agtagaaaga
    40381 cgtttttgta aatttcacta aataattctt tagtgaaaag catcaaaacg aatgaacaaa
    40441 cagataggag tcttacaaat gagaatgaat gtcgaaagtt ttaatcttga ccatacaaaa
    40501 gtcaaagcac cttatgtacg tgtagctgat cgaaaaacgg gtgcgcatgg cgatgtcatc
    40561 attaaatacg acgtccgctt taaacaacca aataaagaac acatggacat gccaagtcta
    40621 cattcacttg agcacttgac tgccgaacta atccgcaatc acgcagatta catcgtagac
    40681 tggtctccaa tgggatgcca aacaggcttt tacttgactg tattgaatca tgaaagctac
    40741 gaagacattt tagatgttct tgaagcaaca atgaaagatg ttcttgaagc tactgaagta
    40801 cctgcaagca atgaaacaca atgtggctgg gctgccagcc atacactaga aggtgcacaa
    40861 gctttggctc gtgaattttt agcaaaacgc gatgaatggt ctgaagtaga agcatagttt
    40921 ctaaaagaac gtaaagatga gaagcaatat agctatctta tcttcgtatt ttattaaata
    40981 tttattgtct gaaaagagtt ctaaacggga aaacaaatag ctagttttca gtttagcgct
    41041 ctttttatta tataaaatag aaaggagaaa actttatgtc tatttataat tttgaaacta
    41101 ctttagaaga cggcactgtc tattcattga aaaaatatgc aggcaaaccg ataatcattg
    41161 ttaacactgc aacaaaatgc ggtctagcac ctcaatttaa acaattagaa gaactttacc
    41221 aagcttatca gacacaaggt ctggttatct taggctttcc ttccaatcaa tttaaacaag
    41281 agctagattc agcgactgaa gcagcagaag cttgtaaaac cacttatggc gttaccttcc
    41341 ctatgcatca attgattgac gtaaatggag aaaatacaga tcctcttttt acttatctta
    41401 aaaatgaagc tcctggtact gtcactaaag caataaaatg gaattttact aaatttttga
    41461 ttgatagaaa tggcaaagta atcgaacgat ttgcaccaca aacttctcca ttgaaaatga
    41521 ccgctgcaat tgaatccgtt ctttaactta ataaaaataa aaaaagatga actatttcta
    41581 gttcatcttt ttgcctttgc gtggcgacgt cctactctca caaggggcaa cccctcacta
    41641 caatcggcgc taagaagctt aacttctgtg ttcggcatgg ttacaggtgt atccttctcg
    41701 ctatcgccac cacactgtgg tgttatcttt tattgagtaa attttgttca ctcaaaactg
    41761 gatttgaagt ca
//
LOCUS       DAIGTA010000020        41625 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.020, whole genome shotgun sequence.
ACCESSION   DAIGTA010000020 DAIGTA010000000
VERSION     DAIGTA010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.020"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            268..2433
                     /gene="acm"
                     /locus_tag="NOB43_001124"
     CDS             268..2433
                     /gene="acm"
                     /locus_tag="NOB43_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HCI0981998.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2705..3190)
                     /locus_tag="NOB43_001125"
     CDS             complement(2705..3190)
                     /locus_tag="NOB43_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCI0981999.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3280..3625
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3670..4311
                     /locus_tag="NOB43_001126"
     CDS             3670..4311
                     /locus_tag="NOB43_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0982000.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4330..4965
                     /locus_tag="NOB43_001127"
     CDS             4330..4965
                     /locus_tag="NOB43_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0982001.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4983..5798
                     /locus_tag="NOB43_001128"
     CDS             4983..5798
                     /locus_tag="NOB43_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0982002.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6117..7553
                     /locus_tag="NOB43_001129"
     CDS             6117..7553
                     /locus_tag="NOB43_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0982003.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7742..10189
                     /locus_tag="NOB43_001130"
     CDS             7742..10189
                     /locus_tag="NOB43_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCI0982004.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10419..11486
                     /gene="rlmN"
                     /locus_tag="NOB43_001131"
     CDS             10419..11486
                     /gene="rlmN"
                     /locus_tag="NOB43_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCI0982005.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11679..12782)
                     /locus_tag="NOB43_001132"
     CDS             complement(11679..12782)
                     /locus_tag="NOB43_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0982006.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13335..13883
                     /gene="aac(6')"
                     /locus_tag="NOB43_001133"
     CDS             13335..13883
                     /gene="aac(6')"
                     /locus_tag="NOB43_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI0982007.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14429..16090
                     /locus_tag="NOB43_001134"
     CDS             14429..16090
                     /locus_tag="NOB43_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0982008.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(16160..16507)
                     /locus_tag="NOB43_001135"
     CDS             complement(16160..16507)
                     /locus_tag="NOB43_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HCI0982009.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16591..17532
                     /locus_tag="NOB43_001136"
     CDS             16591..17532
                     /locus_tag="NOB43_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982010.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17533..18576
                     /locus_tag="NOB43_001137"
     CDS             17533..18576
                     /locus_tag="NOB43_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982011.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18582..19652
                     /locus_tag="NOB43_001138"
     CDS             18582..19652
                     /locus_tag="NOB43_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982012.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19642..20595
                     /locus_tag="NOB43_001139"
     CDS             19642..20595
                     /locus_tag="NOB43_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0982013.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20607..21617
                     /locus_tag="NOB43_001140"
     CDS             20607..21617
                     /locus_tag="NOB43_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0982014.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21902..22723)
                     /locus_tag="NOB43_001141"
     CDS             complement(21902..22723)
                     /locus_tag="NOB43_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0982015.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22820..23098)
                     /locus_tag="NOB43_001142"
     CDS             complement(22820..23098)
                     /locus_tag="NOB43_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982016.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23366..25375
                     /gene="metG"
                     /locus_tag="NOB43_001143"
     CDS             23366..25375
                     /gene="metG"
                     /locus_tag="NOB43_001143"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCI0982017.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25854..26441)
                     /locus_tag="NOB43_001144"
     CDS             complement(25854..26441)
                     /locus_tag="NOB43_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982018.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26616..27938
                     /locus_tag="NOB43_001145"
     CDS             26616..27938
                     /locus_tag="NOB43_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0982019.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            28093..28869
                     /locus_tag="NOB43_001146"
     CDS             28093..28869
                     /locus_tag="NOB43_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI0982020.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28862..29431
                     /gene="rnmV"
                     /locus_tag="NOB43_001147"
     CDS             28862..29431
                     /gene="rnmV"
                     /locus_tag="NOB43_001147"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HCI0982021.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29424..30308
                     /gene="rsmA"
                     /locus_tag="NOB43_001148"
     CDS             29424..30308
                     /gene="rsmA"
                     /locus_tag="NOB43_001148"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCI0982022.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30759..31388
                     /locus_tag="NOB43_001149"
     CDS             30759..31388
                     /locus_tag="NOB43_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982023.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(31512..32621)
                     /gene="ugpC"
                     /locus_tag="NOB43_001150"
     CDS             complement(31512..32621)
                     /gene="ugpC"
                     /locus_tag="NOB43_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HCI0982024.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32830..33252
                     /gene="mgsA"
                     /locus_tag="NOB43_001151"
     CDS             32830..33252
                     /gene="mgsA"
                     /locus_tag="NOB43_001151"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCI0982025.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33575..34111
                     /locus_tag="NOB43_001152"
     CDS             33575..34111
                     /locus_tag="NOB43_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI0982026.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(34151..35914)
                     /locus_tag="NOB43_001153"
     CDS             complement(34151..35914)
                     /locus_tag="NOB43_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982027.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35917..37632)
                     /locus_tag="NOB43_001154"
     CDS             complement(35917..37632)
                     /locus_tag="NOB43_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982028.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(38411..38635)
                     /locus_tag="NOB43_001155"
     CDS             complement(38411..38635)
                     /locus_tag="NOB43_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982029.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            38826..41603
                     /locus_tag="NOB43_001156"
     CDS             38826..41603
                     /locus_tag="NOB43_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0982030.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEVKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
BASE COUNT        13818 a         7290 c         8507 g        12010 t
ORIGIN      
        1 tttgtaagtt aaaaattgga aatatagatt gaaaaaatga aagcaataag taaaataaaa
       61 tgaatatatg cgaaaaaata atttacatta ggaaaaacct tgtaaaaaca gttttttggc
      121 atatttattt tttataaata tttgtaaaat aactatcaat tttttagtta aaagattgga
      181 aatgagtggg ggaggaattg aagaaaggat ttttgagaga tgatatagta ggttttattt
      241 ttagttaaaa taggggagat agaaaaaatg aaaaagtgta gaaatattat tttatcaatg
      301 ttatttatta ttactaatat aacatcactg attcctgttc atgtctatgc ggatgcaggc
      361 agagatatca gcagtaatgt cacttcgttg accgtggacc caacgaatat tacagatgga
      421 ggaaacataa aagtaaaatt ctcgtttgac gaaaaaaaac aaaatatcca accaggtgat
      481 tatctttgga tcaattggcc aagtgaagga aatattcgcg gtgaaggatt ccaaaaagaa
      541 atcccattaa tgattgaaaa taaaaatgtt ggaactttaa cggtcagaaa agattctgcg
      601 caggttgtgt ttaatgaaaa tattaaaaac ctagactcag tagaaggttg ggggcaattt
      661 gagatacagg ccagaaacgt aaccgatacc ggtgaagaaa atacgggacc attcaccgtg
      721 acgagcggtg ataaaacagc tactgtaaat gtgacaaagc cagcttctgg ttcttcttct
      781 agcgtttttt attataaaac aggagacatg ctacctgaag atactaagca cattcgatgg
      841 tttttgaata ttaacaataa cggcacttat gttgaacaac cagttaaaat cagtgatgaa
      901 atccaaagtg gacaaagatt agatccaagt acgtttgaaa ttaatcaaat acacttaggt
      961 gaacagaagg tttatagagg agaagaggga atccaacaat ttttacaaga tttccccagc
     1021 gctacattta atttttcagt aactgataat tacattgaaa taactatacc aaaaaacttt
     1081 gtcaatctta ggaaaataat ggtgagttat aagacgatca tagaaaaccc agaacaaata
     1141 aattttgaga atcattcgga agcttggttt aaagaattta ataaacctgc tgttgatgga
     1201 gaaagtttca atcatacagt taaaaatatt tcagcttctg gtggagtcaa cggtacagtt
     1261 agaggcgaat tgaagatttt caaatatatc aatgacacag agattggtat cccaaatgtg
     1321 actttcgaat taagacgagc agatgaacag cctattcaag gacagtctag tatcctgttg
     1381 acttcgaatg aacagggaga agctagtatc aaaggcctgc aagtaggaga ctatgttgta
     1441 aaagaaaaag aagcacccaa ttggattgat tttgatccac taagttcaaa tgaactcaaa
     1501 ttctccataa acgaaaatga tacagaggga gtcagtttac ctatttataa caagaaaaag
     1561 gttacgaaca tcacagcaac taaaatttgg aacggtggaa ccactccaag accgagtatt
     1621 tattttaaat tattcagagc aagtacaaac aattgggaac cagttcctga tgcagaaaca
     1681 aaacgattag acaatggaat aacttcagtg acttgggaag atatccaaca gtatgatgat
     1741 agtggaaacg aatatacgtt taaagtgcaa gaagtagatc aaaacggaaa tgattatgtc
     1801 ccttcaggtt atcaaaaaat tgaaaacggg ctagtcgtta caaatgagaa taaagaagtc
     1861 atttcagtct caggacaaaa aacatgggaa gacaatgaga accaagacgg caaacgaccg
     1921 acgacgatca cagtaaatct attagccgac ggtcaaccga tccaacacaa agaagtaagt
     1981 gaaaaagatg attggcgcta tcgtttcaca aatctgccaa aatacagaga cgggcaagaa
     2041 atcatctata ctgtaacgga agacaacgtg cccgaataca gtacgacgat tgacgggtat
     2101 aacatcaaaa acagttatac accggaaaaa acaaatatat ctataccagg tagccatata
     2161 acaccgtgga aaaattttcc agagaagaca gagagagaga aaattagaaa tctattctct
     2221 caaaaattgc aaatatttgc tcatacagga gaatccagcg aacaaagaag caattatatt
     2281 agtaagagag ctgtacctaa acagataaca aataaatcaa aaagcattct tcctaaaaca
     2341 agtagtaaaa aatctagttt tgctgtaatc attggtttat tgatagtaac tatctgtgct
     2401 gggatattct tacaaaaata taaaaaagtt tagttagaat ataatatttt ttgttaaata
     2461 tgactgaaat caaaagaata aaattccgat ttataatcga aaaaagaagc atttttatat
     2521 atgcttcttt tttcgtagaa tcaataaata tggatttggc taactatgga agaatactcg
     2581 tattagtttt cagcgttcat actagttgtt acattgtttg attggccaaa agaatttctg
     2641 atatattttg tgctaaataa agaaaaagac gcttgaattg ggaaataaga aaactactct
     2701 atcattacaa attttcataa actggcagat gttctaagta aacaagtatc ttttcaaagt
     2761 cggaaaaatc cataatcaac gtagtggtat tgatatttgg atgaaagcct acggtatctt
     2821 gacgatcaat agcagcatcg atcacgactt ggattttttt ctctttgtcg tgcatcaatg
     2881 ctaatggagt cactgtacct gctggaacgc ctaggaggtc aggaagctgt tcttcagaaa
     2941 caaaagataa gcgcttttct tttaattgtt cagctagttg ttttaaatcg gcgtgctttt
     3001 catcaggcaa gatgacaaga tagatttgtt ttccttttct tgatttcaat aatagatttt
     3061 ttacttgcgg accaggtagg gaaaaaggga catttttgac tgacgtaatc gcaggatgat
     3121 cgactttttg aaaagagata cccagttttt ttagtagttc ataagcttct tgttcggttg
     3181 cacgactcat cgcgcatcac cctccttttt ttattagtgt atcataaaaa agagttgaca
     3241 aatgaaaaat aatcatgtaa attacacgta aagttaaaac aaatgacatc gaaaagaaga
     3301 gtagccgtta ggtgttttta gagagtctct ggttggtgga aagaggcagc agttaaccgt
     3361 gaaacacatc ttggagtcga ttttctgaag cgtatagtag gaaaatccgg ggagcccgtt
     3421 acagctgcgg tcgttgctag atgaccagat aaggctggct tttccgtgag gagtcggtaa
     3481 aaaaaggtgg aaccacgtga ttaacgtcct ttgatcttcg gatcaaagga ctttttgttt
     3541 tcatctgaac ggcaacgact gtgtgaggtt ttttctgcaa ggaaaaaata aacagaggtg
     3601 gaaccacgta taatacgtcc tcttggcatt tgccaagagg atttttttat tttaaaggag
     3661 gaaaagaaga tggagtattt gattgaagtt atgccgcaat tattagtagg agcactcaca
     3721 acattgaaat tatttttatt taccttgatt ggctcattac cattagggat tgttttagca
     3781 ttaggattgt ctttgcattt taagccgcta cgctacttgc ttcaaacata tgtatgggtt
     3841 atgcggggaa caccgctgtt gttgcaactg atttttattt tttatgggtt gccgacgatt
     3901 gggatcgttt ttgatcgttt cgaagcagca ctcattgcct ttatcttaaa ctatgcagct
     3961 tattttgcag agatctttcg tggagggata caatcgattc ctcaaggtca atatgaagca
     4021 gcgcaagttt tgcaattaag tccctttcaa acggtgacga aaatcgtcat cccacaagtg
     4081 acaaagattg ttttaccttc tgtagggaat gaagttatca acttggtcaa agattcttcc
     4141 ttgatctata tattaggttt aggtgacgta atgcgtgctg ggaaaatcgc gatggaacgc
     4201 gacgcgactt tactgccttt gctaggcgtg gcaatcatct atcttacatt gactggtatt
     4261 ctaacaatcg taatgaaaca agttgaagga aaattaaatt attaccgcta actgatagga
     4321 ggaagaaata tgattgaatt gaagaaagtg aacaaagcat ttggtgaaaa aaaaataatc
     4381 aaagatttga atctaatcat tccagatggg aaaacattag ctatcgtagg tccttccggt
     4441 ggcggtaaaa ccacgctttt acgtatcttg gctggcttag aaagttctga cagcggagaa
     4501 ttttatttag acggtgtacc gttcaaccca ttcgagctta aaatgaaaga acaagttgta
     4561 ggagtcgtat tccaagactt ccagctattt ccacatctga atatttttga aaacattacc
     4621 ttagcaccaa aaatggtatt gaaacagaca aaagaagaat acaccaaaaa agcagaagaa
     4681 ttagcggctt cattagggat tagtgattta ttgaatatct atccttatca gctttctggc
     4741 ggacaaaaac agcgggtagc gattgccaga gcattggcta tgaatccacg ggtattggct
     4801 tatgatgaac caacaagtgc tttagatcct gaattacgcc agcaagtcga gcgtttgatc
     4861 ctatcattga aagaagatgg ggtaacccaa attattgtca cccatgattt agtatttgca
     4921 gaaaatgtcg gtgatcaatt actaaaagtt tccccaattc attaagaaag gagaagatag
     4981 agatgaaaaa aaccagtttt ctattcgctt tgatcgcagg tcttcttctt tttgcaggct
     5041 gttcgaacaa aaaaacttca gcagataatt gggcgactat caacgaagag aaaaaaatcg
     5101 ttataggttt agacgataca tttgttccta tgggatttag agataaagac gggaagctca
     5161 caggatttga tattgattta gccaaagcag tctttgaaca atatgggatt acggtagact
     5221 ttcagcccat tgactggtca atgaaggaat ttgaactgaa caatggaacg atcgatttga
     5281 tatggaacgg ctattccaaa acgccggcaa gagaaaagaa agtgcaattt acaaaacctt
     5341 atatggaaaa cgatcaagtg ctgatcacac ctaaagaatc aggaatcaca aactttggac
     5401 aaatgaataa taagagatta ggtgcgcaaa atgggtcatc tggttatgat gtatttacga
     5461 aacaaccaga agtattaaaa gagatagtca aaaaccaaga tgctgttttg tatgatagtt
     5521 ttaatgaagc attgatcgat ctgaaaagca gacgggtcga tggtctgctg atggataaag
     5581 tatacgcaga ctattatttg aaacaaagaa acgaactaga agacttcaac ataacaaaag
     5641 gttcttatga gagtgaggat tttgcagttg gtgcacgcaa gtcagatagt acattagtga
     5701 aaaaaatcaa tgaagcccta gatcaactag agaaaacagg tgaattccaa aaaatatccg
     5761 ataaatggtt tggcgaagat gttacgccga gaaattaaca aataggggac tgtgacaaaa
     5821 gacgtgtcac agtccctttt tccgaataaa cagtgttctc ctgccaactc cttgtgactc
     5881 ggagctgaat ggcaggctca caacctcttg gtaaacggtg ttcaaaagcc agtttttcgg
     5941 tattaagcca aatttatgca aaaatgtaga aagccatttt cacaaaattt ttcttactac
     6001 tcgaaactaa gcgacttttt cacaacctcc tttacataat tttattttgt tgtggaaggg
     6061 gtttcgtgtt attctaaaag aggaacgatt gaaggttata ggaaaggaag agatgaatgg
     6121 aacacaaaga acttacctca tttccaaaag attttctgtg gggctctgct tctgcagcgt
     6181 atcaagtaga aggagcttgg caagaagatg ggaaaggaga atcagtctgg gatcgatttg
     6241 tacggatacc tggaaagaca tttaaaggaa cgaacggtga tttggcagta gaccactatc
     6301 atcgttataa agaagatatt gctttaatga aagaacaagg tctgaaagct taccgcttct
     6361 ctgtagcttg gacacggatt tttcctaatg gacgaggaga agtcaatcaa gctgggctcg
     6421 ctttttatga gagattgatc gacgaattga ttgaaaacga tattgaacct atgttgactt
     6481 tatatcattg ggatcttcca caagcattgc aagatgaata taatggttgg gaatcacgtc
     6541 agatcattga agatttcact cattatgcag aaacattatt tgaggcattc cgcgggaaag
     6601 tccattactg gattagtttg aatgaacaaa atatcttcac ttcattaggt tatttgttag
     6661 cagcacatcc gccaggtgtg acagacccga aacgaatgta tgaagttaac catattgcta
     6721 atttagcaaa tgcatctgtc atcaataaat ttcacgagtt agaaatgcct ggaaaaatcg
     6781 gaccaagctt tgcgtatacg ccaaattatc caattgacag taatcctgaa aatgttctgg
     6841 ctgctgaaaa tgcagaagac ctgatggcca attattggat ggatgtctat atgtggggaa
     6901 aatatccgat tgctgccatg aggttcttag aagaaaaagg atgggcacca acgattgaag
     6961 ctggcgatgc agaattgcta gaatctgcta aaccagattt tcttgggatc aattactatc
     7021 aaacggcgac gaatgcattc aatccattaa acggagttgg tgctggaaaa atgaatacga
     7081 caggaaaaaa aggttcatca gaagaaactg gagttcctgg aatgtataaa aaagttgaga
     7141 atccatttgt cgaacgaaca aattgggact gggagattga cccagaagga ttaaggatcg
     7201 gactgcgtcg tatcacaagc cgttaccgca tgccggtact gattacggaa aatggcttag
     7261 gagagtatga caagttgaca gaagataaac aaatccatga cgactatcga atcaattact
     7321 tacaaagcca cgtcaaagcc atcaaagaag caatttcgga tggagcagaa gtcctaggct
     7381 attgcacctg gtcttataca gatttgctta gctggctgaa cggttatcaa aagcgatatg
     7441 gatttgtata tgttgatcaa gacgaaacac aagaaggatc tttggaacga tataagaaag
     7501 acagttatta ctggtaccaa aaactgattg aagaaaatgg agagaacctt tagttcacat
     7561 acttaaaaca agaaggtacg gctggatatg gccgtgcctt ttcttgataa aatcatttag
     7621 aaattaagaa aaactgtaaa ataagctgaa aaatgaaaga aagcgtcagt tctttcaaac
     7681 aaaactttag ttcccttact tttttttgta taatgaaact tgatgaaatg agggataata
     7741 aatggcacaa aagaaacggc ctactaaaaa aaggaaaaag acgaaaaaaa cgaaaaagca
     7801 aaaacagcag caggaacaaa tgctgacgat tggtgttggg tttgccttga ttttatttgc
     7861 tgtcttcggc tttttaaaat taggtttttt aggaatattg attgcaaacg gctttcggat
     7921 cattgcagga aatacttacc aaatcctctg tcttttatta gccgtattag gattttggat
     7981 tgtcattaag aatacagagt tttcaattgg taaaaaccga cgctggtttg gcggcatact
     8041 cttttatttc ggtatcttat tattgttaca tgcccattta tttggcaaac tccatactgg
     8101 ggaaccaaat atcatgggga cgacatggga tttgttagcc agtgatataa aacaaagtca
     8161 agtagacaat aacgttggtg gtgggatgat tggagcaatc ctttatcatt ttacttactt
     8221 cttgattgca cagcctggaa gttatttagc agcagtgcta ttactggcag gaggagcatt
     8281 cctgttcagt aatctggaag gctatcagct gttaaatggt atccaatcaa ttggagaacg
     8341 agtacaggaa ttattggaag gtgatcctgc caagcaagct cgaaagcaag cggcaaagga
     8401 agagagaatg aaacagcgcg cagaagcgaa agaagcaagg cgcttagctg caaaagaagc
     8461 tgcagaaaaa gaagctgcag aatatgagaa gaaaaaagcg gtgagccagc aaagggaaaa
     8521 tactgctgat gaatggcagg aaccagaaaa tacagagccg gagcagctaa gttttgttcc
     8581 aatcgacagt tttcaagaaa atatccatcc tgcgaatcta gagaaaccag taccagatac
     8641 accaaaacag accaatacag cagaaggttt ttcagatgag ttgccagagg atgacggtac
     8701 ctcattagaa tttgagattg aagcagaaca ggaaaatcaa gactatgaat taccgacagt
     8761 tgatttgctt gattctatac caactgtgga tcaaagtgat gagtataaaa aaattgaaaa
     8821 aaatatcggc gtattagaac aaactttcca aagtttcggt gtcgatgcca aggtcgtcaa
     8881 agccagctta ggaccatccg tcacaaaatt cgaagtccag ccggctgtag gggtaaaagt
     8941 aagtaaaatt gtgaacttaa cagatgatat cgcgcttgct ttagcggcga aagatgtccg
     9001 gatggaagca ccgattccag gtaaatcact gattggtatt gaagtaccaa atggaaagat
     9061 cagtatggtt tcctttagag aaatcatcga agcacaacca aaccacccag ataaattact
     9121 agaagtacct ttaggacgtg atgtttctgg acgggtacaa acggctgatc tttcgaagat
     9181 gcctcactta ctcgtggctg gttcgactgg tagtgggaag tcagtagcaa ttaatgggat
     9241 tatcacaagt atattaatgc gtgctaagcc ccatgaagta aaactgatga tgatcgatcc
     9301 gaaaatggtt gaattgaata tgtacaacgg catacctcat ctgttgacgc cggtcgtgac
     9361 gaaccctaga aaagcagcgc aagccttaca aaaagtagta caagaaatgg aagaacgata
     9421 tgaaaaattc gcggcaaccg gagtaagaaa tatttctggt tacaatgaat ttgttcaaca
     9481 gaaaaacttg gaaaacggaa cgaaacatcc aaccttacca ttcatcgtag tgatcgtaga
     9541 tgaattagct gatttgatga tggtagccag caatgaagtt gaagatgcga ttattcgttt
     9601 agcgcaaatg gctcgggcag cggggattca tatgatccta gctactcaac gtccaagtgt
     9661 ggatgttatc acaggaatca tcaaagcaaa tgtaccttcc agaatggcat ttgcggtatc
     9721 aagcggtaca gattctcgga cgatcattga ttctaatggg gcagaaaagc tcttagggcg
     9781 aggagatatg ctattcttgc caatgggtga gaataaaccg atccgtgtgc aaggagcatt
     9841 catttctgac cacgaagtag aacgggtcgt tcaatttgtt acagatcagc aagaagctca
     9901 ttatgaagag aaaatgatgc cgacagatga agttgaaacg acaggtgctc cagaacagcc
     9961 acaagatgag ctgtttgaag aagcaaaagc acttgtcgtt gaaatgcaaa cggcaagtat
    10021 ttcccttctc caaagaagat ttcggatcgg ttacaaccga gcagcacgtt tagtagatga
    10081 actggaagct catggagttg ttggcccgtc agaaggaagc aagcctcgga aagtattcat
    10141 tgagcaggaa gaaacatcag aaacgttgcc ggacgataat gacatgtaaa acttgtgtga
    10201 tgaagggttg aaaaacgaat aaccaataaa aagacaaggc atgatgatac caaaagaaaa
    10261 aatggttttt ttccatcttt tctaatacgg tatgatgtct tgtcttttta gtttttgtga
    10321 gattaaagtt ctattcgatt tatttgtgaa gtattgcatt aaggaaatga atcatgtata
    10381 gtatgtagcg aaactttgag aaaaagaggg aaaatacttt ggaaaaacag tccatttatg
    10441 gcttgacgaa tgaagaatta atcaattggt ttatagaaaa cggcgagaaa aaattccgag
    10501 ctgcccaagt ttgggaatgg ttgtatcaaa aacgtgtaag taatttcaca gaaatgacga
    10561 atctatcgaa acaattgatc gaaaaattat cggagcattt tatcatcaat cctctaaaac
    10621 agatggtcgt ccaagaagct tcggatggta cagtaaaata tttgtttgaa ctccctgata
    10681 aaaacatgat tgagactgta ctgatgagac aagaatatgg cttgtcagtt tgtgtgacga
    10741 cacaagtagg atgtaatatc ggctgtacgt tttgtgcaag cgggctgctc aaaaagaacc
    10801 gtgatctgac tgctggagaa attgttgcac agatcatgat ggtccaacat tattttgatg
    10861 agcgcaatct tggcgaacgc gtttcacatg tcgttgtaat ggggatcggt gagccatttg
    10921 ataattacga caatgtaatg gactttttgc atatcatcaa tgatgccaaa ggattggcaa
    10981 ttggtgctcg gcacattaca gtttccacta gtggattagc acacaaaatc aaggaattcg
    11041 ctaataacgg cttgcaagtc aatctggcta tttccttgca cgcgccgaat aatgaggtgc
    11101 gaacatcgat catgcggatc aaccgaagtt tcccaattga gaaattgatg gaagctgtgg
    11161 atgagtattt agagaaaaca aaccgtcgaa tcacgtttga atatatcatg ttgaatcaag
    11221 taaatgatag accagagcat gcgcaacaat tagcagatct attaaaagat aagaaaaaat
    11281 tagcatatgt caacttgatt ccatataatc cagtcagtga acatgatcaa tattctcgca
    11341 gtccaaaagc tgatgtattg agattttatg atgtattgaa gaaaaacggc gtaaactgtg
    11401 tgatacgtaa agaacatggt acagatattg atgcagcttg cggacaattg cgaagcaagc
    11461 aaatgaaaaa aacagttgcc aaataatcgt atcctactcg ttttttcaat taccataaaa
    11521 ggagcagttt tcttaattaa ggaactgttc aacttaaata agagaaaaga ttctatagcg
    11581 aaagctataa agcttttttt gacaagaaaa accctcatca agcaaagaaa tgtcctcaat
    11641 ttgatgacag cctgcttgat gggggtttta gcaattattt aactgatttt cttatatcct
    11701 tgctggcttt cttgtgtagc atgataagtt tctacgtcaa gaatggcctg tttaaatttt
    11761 tctcgggtga tttcataagg cacatgttta atatcatttg ttgccatggc tttatctaag
    11821 attgcttcta aatcggtcgt gacattgaga ttcatgtcgg ttaacgatac tggaagttgg
    11881 ttctttttca taaacacata gattttatca aacaaatcga actgctgatc catcatcaat
    11941 aaggtcagta caccataact gacagatgct ccgtgaaggt atccctccat tttttctaga
    12001 acagtcgtac cgtaatagaa tgagtgtgcc atagcagaat tatagttatt gttaactaaa
    12061 acagaaacca atccggtagt aacaatgata tccgaaacga cttgttcaat tgcatatgag
    12121 ggacgatcgt cggcactatc tttcaatgct tgcgtaccat aagtcaagag acgatcaatg
    12181 cacatttttc cgatttggat tcctaatcta tccgtgtagc ctagatcatc gccacgagca
    12241 gaaaaagtag attcgacttc tttggataaa gcatcgccaa tacctgccca taagtattta
    12301 tcaggtgctt cggcaataat tgctgtatca atgaaggtgt gtacaggtgg ttttgaagga
    12361 aagaagagtc cgtccattac gccttcttcg ttatagatga cacataccgc agtgacgggc
    12421 gaacagttcg aaccaatagt gggaaaggtg aagactggtt tagctagttt ttcaccaatg
    12481 acttttacag tatcgcaagc acggccacca ccgactgcaa acaggacgtc tgctttttgg
    12541 acactttcat gctggatcaa ctgttcaata tttccataag ttgaattacc cccgtaccag
    12601 agactggcga caacctctat ttcctgtgtc aaagctactt ttattttgtt ttctgccttt
    12661 gaaagtgcag tcttccctcc aatcagcact acttttgtcc catattcttt gacgattcca
    12721 tttgcttttt catacgcatc tgttccaatg gtataatttg gtaagaaaac actttgactc
    12781 atattcattt ccttctttct tcgttgaaac gggttaaaat tttaaagagt gatcgatctg
    12841 actgcggctg tagatggagt agaggtgaac ctaagacagg ataagtgatg aataaggtgg
    12901 catgaacacc ttgaaatcat caataagtat cctaaaaacg aacaagtaca aaaacattga
    12961 aaacgacaat aatgaatttt tgttcctctt agtatttcta ccgattccct ttgctttttt
    13021 gtaattatct aaaaattcta aaaattaaga ttattatatg aaaacaggtt ttatttgtca
    13081 attcataatt ggtttttttt aaagcaaaag ataatctata tcatgatgaa caaacagagt
    13141 tttttcctcc aattgatggc tttcctgatc tttcctattt tgaataaagt gtttctgtat
    13201 aattttttta ttttataagt aagataaata atgaaagaat agagatactg attggtagct
    13261 aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat aagcaagaac
    13321 aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta ttgaaagatc
    13381 agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc tcggcagaag
    13441 aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac caagatgagt
    13501 tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa ttgcatccat
    13561 tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc aattacttag
    13621 aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat gatttagacc
    13681 atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa gtggcttcca
    13741 tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat aaaatcgtag
    13801 gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca aaaacgatta
    13861 ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc agcttcaaga
    13921 aataagaagg aatttacgaa aattacttct tgaatttttg tgaaattcca acttatttcc
    13981 gaagaagcta cttttggaac accgtgtacc agaggttgtg aaaaagtcgc ttagtttcga
    14041 gtagtaagaa aaattttgtg aaaatggctt tctacatttt tgcataaatt tggcttaata
    14101 ccgagaaact ggcttttgaa caccgtttat tcagataagg gactgtgaca agacttttgt
    14161 cacagtttct ttttgtttat tcttttttat ctttgtatgg caataataga caatataacg
    14221 aaaattattt aatggctttt ggaagaccat ggaaaacctt gtacaaagct attttttctg
    14281 aaaaattcct tgaaacctca cgaaaaaatc attattttat gaaaaagaca aaaaaaagtg
    14341 ttgatttttt aataattatt cattaaactc ttaaacaact tcagaaaata ttaattattc
    14401 tgaaaattcc aataaagggg tacgtaaaat gaaaaagaaa tttacatttg gtttggttgc
    14461 ggtatgcggc cttgtacttg ctggatgtta tggcggcagt tcagccacaa gcagtagttc
    14521 agcaaaaagc ggttcagcag atggaggagg cgtatttaac ttagtcgtgc ctcaagaaat
    14581 gcctacagct gacttatcag ttgcaacaga tacaatcagt tttacagcat tgaataacgt
    14641 ttatgaagga atttaccgtc ttgatgaaga cagcaaacca cagccggcag gagctagcga
    14701 gttggcagaa gtcagtgaag acggattaac ttacaaaatc aaattacgag aagacgcaaa
    14761 atggtcaaat ggtgatcctg ttacagcagc ggattacgtt tatggctggc aacgaacagt
    14821 agacccagct acagcttctg aatatgctta cctgtatgcg ccagttgaaa atgcagaaga
    14881 cattacagct ggaaagaaag ataaatcaga actagggatc aaagcagttg gtgactatga
    14941 attagaaatc aaattgacga aacaaacacc atatttccaa tatctgcttg ctttcccatc
    15001 atttttccca caaaaacaat ccgtagtgga agaaaatggg gatgcctatg catctgcaag
    15061 tgataaagct gtttataatg gaccattcac attagaagat tttgatggac caggaacaga
    15121 tacagaatgg acttataaga aaaatgatca ttactgggac aaagatacag taaaactttc
    15181 tgaaatcaaa gtcagtgtag taaaagaatc ttctactgca ttgaacttat tcaaagatgg
    15241 ccaagcagat gacgtgatct tgtctggtga gttagcacag caaaacgcaa acgatccagc
    15301 ttatacttct gttaaagaag cgcggacaag ctatatcgaa ttcaatcaac gtgaaaagaa
    15361 ttcaccattc aacaatgtga acctaagaaa agctatttct tattctatcg atcgtgaagc
    15421 tttagtaaaa caagtactag gtgacggatc agttgtctct acaggattga tcccatcaga
    15481 tatggtaaaa agtccaacaa cgaacgaaga ctttgcaaaa gaagctggaa aattagtttc
    15541 ttatgacaaa gataaagcaa aagaatattg ggaaaaagcg aaaaaagaat tgggcgttga
    15601 ttctttagaa tttgatttga tggcttctga tgatgattca tcgaaaaaag taatcgaata
    15661 tgttcaaaac tcaatccaag aaaacttgga tggcgtaaca gtcaaaccaa cacctgttcc
    15721 attctctgta cgtcttgacc gctcaacttc gggtgatttt gacgcagtac taggcggatg
    15781 ggctgctgac tatgcagacc caagcagctt tactgatttg tttgtcacag gtaattcata
    15841 caaccgtggt cgctggagca atgcagaata tgacgaagca gttaaagcag cttcatcaac
    15901 agacgctggc gatgaacaag cccgttggga tgatttccaa aaagcaatca agatcatctc
    15961 tgatgatatg ggtgtcgttc cggtgtacca aaaagcagaa ggtcacctag tgaatgaaaa
    16021 aatcaaaggt atcgttcacc atgcggcagg cgcttcatgg gattacaaat ggacatacgt
    16081 tgaagaataa tcgttaatac cgtgagcatg agaaaaaacg aggctgcggc aaatgtcgca
    16141 acctcgttct catattcact tatcctaaca aagaaaaaag catgaaaata gcagaaagag
    16201 caattagtat tccggcaatg atcagccaaa agctgtacat accgtagctg gcagacgaga
    16261 gcgaggaaaa ttctggtttt ttctttcggt tccttgttcg tgcaagatgg accgatcgct
    16321 gaaaatgatc gaagaaaccc gaagaaaaga cccataaaaa accgccgata atcagaaacg
    16381 gcaatgacca taagaataga tcattagata attgaatgag tgtaaaggaa tggttgatga
    16441 gattttttat taaaataacc agaatcagta gaaaagctac tgcgtagggg atagattttt
    16501 ttttcatttg attgctcctt tatttttggt tcattatcta ataatgtagc gaaacatctg
    16561 tcagaagtca aaagctaggg ggaaacatta gtgaatagtt atatcaaata tgtattaaaa
    16621 cgtgtctttt tcatgatcat cacgctttgg ttaattgcaa caatcacctt tttcttgatg
    16681 caattgctgc cgggcacgcc atatacgaat caggaacgtt tgagtcctga aacaatcgag
    16741 atgctaaata aacaagtcgg tttggataaa ccagttatcg tacaatatgg gatttatctt
    16801 tctaatttgc ttcaaggaga ttttggaatt tccttccaat ttaaaaacca gccagtcgca
    16861 catttgttag ctggaagaat cggaccatcc ttgcagttag ggttacaggc aattatcttt
    16921 ggaacagtcc tagggacgat tttaggaacg atctctgcca tgaagcaaaa tacatgggca
    16981 gatacatctt ctacactcgt agcgatatta ggtcgttcca ttccaaactt tgtatttgct
    17041 gttttattac aatatatctt tgcaatcaaa ttacaagttt tgccaatcgc aaaatgggat
    17101 ggctttgtgt acacaatctt accaacaatt gcgttggcca tgtcgccgct tgctgactct
    17161 gctcggttta tccgtacgga aatggtggaa gtactgcata gtgattatgt ggaattagca
    17221 aaagcaaaag gattgagccg ttgggaaatc gcctttaaac atggtcttcg aaatagtttg
    17281 attccattga tgactttatt aggaccgtta gctgtagcat tgatgaccgg atcactggtg
    17341 gtagaaaata tctttgctat tcctggtatc ggggaacaat tcgttaagtc aatcacaaca
    17401 aatgattatc ctacgatcat ggctgtaacg atcctttact catttatgct gatttttgtt
    17461 attttgatcg tggatctatt gtacggtcta gttgatccaa gaattcgtgt ttcagaaggg
    17521 agccgaggat aaatggaaat gataccaaag cgttatgaaa cagttgcaga tatccctgcg
    17581 gatgaatttc ttccattaca aaaaaatacc gaagaagaac gtgaacagat tactgcacct
    17641 tctttgaatt ttatccaaga ttcatggcgc cgtttaaaga aaaacaaagc tgccgttatt
    17701 tcaatggttt tactattggt catcattttg atctctgtga tcacaatctt tgtttctcct
    17761 catgatccaa ctgcccaaaa cgtggcttat atcaatttgc ctcctcgtat tccgggaatc
    17821 aatatcgatg gattgaatgg aaaagcaatg gttggtggtg aacttgttga taaatatgct
    17881 caagcaaacg tcccttcaaa cgtaaatttc tttttaggaa cagacggttt gggacgtgat
    17941 gtattaagcc gcttatttat gggaatgaga atctcgttgc tgatcgcatt tattgctgca
    18001 ttactagatg taacgattgg tgtagcttac gggttggttt ctggtttgtt aggcggacgt
    18061 gtcgataacg tgatgcaacg ttttttggaa atcttatcag gaattccaaa cctcgttgtc
    18121 atgattttga tgttggtcgt ttttgaacca ggaatttttt caatcgtggc tgctatggcc
    18181 atcacaaact ggataccaat ggcacgtatc gttcgtgcac aaacaatgaa attaaaagat
    18241 caagaatatg ttttagctgg attgacatta ggtgaatcaa gaatgaaaat tgcattcaaa
    18301 catattttgc cgaatatctc tagtgtcatt attattcaaa tgatgtttag tattccatct
    18361 gctattttct tcgaagcctt tttaagcttt atcggtttag gtcttacgcc tccgtcagct
    18421 tcattaggaa cgatgttgag cgaagggtac aagacattcc tgtatctgcc ttatctatta
    18481 tggattccgg cagtaacttt atcggttatc atgattggct ttaacttact tgctgatgga
    18541 ttgcgtgatg cctttgatcc taaaatgaaa gagtgaagac gatgacgaaa attttagaag
    18601 tgaaagactt agaaatctct tttgatacgt atgctggaaa ggtacgagcg attcgcggtg
    18661 tcaattttca tttgaataaa ggagaaacat tggcgatcgt tggggaatct ggaagtggaa
    18721 aatcagtgac gaccagaagc atcatgcgct tgctgtcaag caacgccaat atagatgctg
    18781 gtcaaatcct ctttaaaggt aacgatatcg ttggaaaatc agaaagagag atgcaaaaaa
    18841 tccgtggtaa agaaatagcg atgattttcc aagatccaat gacctcttta gatccgacga
    18901 tgcccattgg gaagcaagtc gctgagtccc ttagaaagca taataaagtt tcaaaaaaag
    18961 agggacaaaa agctgcatta gaattgctta aattagttgg aatacccgaa gctgagaaac
    19021 gtatcaacag ttatccgcat cagttctcag gaggtcagcg tcaacggatc gtgatcgcga
    19081 ttgcactggt atgttatccg gaaatcctga ttgctgatga acctacaaca gcgcttgatg
    19141 tgactattca agcacagatt ttggagctgc tgaaagaaat tcagacaaaa atcgatacat
    19201 caattatctt tatcactcat gaccttggtg tagtagcgaa tgtcgctgat cgtgtcgctg
    19261 tcatgtatgg aggaagaatc gttgaagttg gaacatcgga agaaattttc tacaacccgc
    19321 aacatcccta tacttgggga ctgcttggtt caatgccgac attagatagt gcgaacgatc
    19381 gattgtatgc tattcctggt tctccaccgg atttattgaa cccgccaaaa ggagacgcat
    19441 tctatccaag aaatgaattc gcgatgaaaa tcgatgcaga acaagaacca ccattttttg
    19501 aactatcaaa aacacacaag gcagcaactt ggctacttgc tccgcaggca cccaaagtga
    19561 caccgccaga agaaatccaa cgtcgctggg ctatctttaa agagaaacaa aaacatactt
    19621 acggtcaagg aggaattgct gatgccaaat aaactacttg aagttaaagg attgaaacag
    19681 tatttcaatg taggaaaaaa gaatgaagta catgctgtaa atgacatcag ctttcacatt
    19741 tatgaaggag aaacattcgg tttagttgga gaatctggaa gcggaaaatc cactactggc
    19801 cgtacgatca ttcgcttgaa tgaacctact gatggtgaga tattattcga cggtcaagat
    19861 ataacgaaga tcaaagataa aaaaggtttg acgaaattcc ggcatgatgt tcagatgatc
    19921 tttcaagatc catacgcttc gttgaatcct cgtatgaaag tcagagatat cattgccgaa
    19981 ggaattgatg ttaatggact agctaaatca tctgaagagc gtgcaaaaaa agtcgatgat
    20041 ctattgagaa ctgttggatt gaatccaagc cacggtactc gttatcctca tgaattttca
    20101 ggtgggcaac gccagcgtat tggtattgca cgagcattgg cagtaaaacc gcgttttatc
    20161 atttgtgatg aaccaatttc tgcactagat gtgtcgatcc aagcccaagt ggtcaatttg
    20221 ttgcaagatc tccaaaaaga acatcaattg acctatctat ttattgcaca tgatttgtcg
    20281 atggttaaac atattagtga ccgaatcggt gtaatgcata acggcttgtt attagagatg
    20341 ggaacaagtg atgaaatcta taatcacggt gttcatcctt atacagaaag tttgttatct
    20401 gctattcctc taccagatcc agaccatgag agaaaacgca gaagaatcaa atatcaacct
    20461 gaaccagatg acggacaagt acgtcaactt cgtgaaatcg caccagaaca ttttgtctat
    20521 gcaactgagc aggaagtccc atattacgca aaaaaactaa aacgacaaaa ggaatctctt
    20581 ctggttgcta actaggaggg acatagatgc taaaagcttt taaattccgt atgtatccga
    20641 cagaagaaca aaaacagcaa ttgattcgta cttttggatg tgctcgattt acctataacc
    20701 atttgctgaa aaagcggcag aaaagttggc aacaaacagg agtagccaat ttttcgctca
    20761 cacccgctac attaaaaaaa gaatacccat tcttaaaaga agtagacagt cttgctttag
    20821 caaatgcaca gcttaatttg gatcgggctt ttcgcaatta tttcaaggga cgtgccagct
    20881 tcccaaagct taaaacgaaa aaaagtatgt ggcaatctta tacgaccaac aaccaaaccc
    20941 gtacgatcta tctggaaaat ggctacttaa agttaccaaa acaaaaagaa ctaatcaaga
    21001 taaatcagca tcggccagtt gaaggatcga ttcgctccgc tacgatttct gctcgatata
    21061 atgaagaatt ttatgtcgca ctactttgtg atgtttcgcc agtaaaaaaa gaatctttag
    21121 ctaaatggat cgggatcgcc tatcatccga agacattgat ccaaacatct cgacctctag
    21181 aagtaacttt accaaaattt caccagacag aagaaaagct gcaacatgca cagcggaaat
    21241 tgaatgtgaa agtccgctcc gctcaccata gaaagatcag gttagatcag gcaagcaatt
    21301 atcagaaaca aaagagaaaa gtaatggatc tttatctgaa acaaaagaac cagcgagaag
    21361 attatcttga acaattatct gggaaattgg tcaaacaata tgactactta tttgtagaat
    21421 cttttccaaa agaagaggca catgctgatt tttctattca cgactggcat aaattaataa
    21481 caaaattgcg ttataagtcc caatggtata ataaaaaatt tcttttgatc aataccgacg
    21541 gagcagaaga aagcaattcc gtaagaaaga gccaagtagt agaaaaaatg ggcagacatt
    21601 cggttatcaa gggataaaaa atgaatgaaa ctgataggag cgttagggtt agccttgtta
    21661 ataaaaagtc ttaatgactt ttgtttctag gaatttttct tttgaagaaa agctcactaa
    21721 ttatgacaaa ccaataaaac aatagcagaa aaagttcgta cgagcttttt ctgctattgt
    21781 taatttttta ttcagaaagt ttacgaatac atcaaaattc tgaaacaaaa aacgtaactc
    21841 acaaagagtt gtttttgcgt tttttcttga atgattaggt ctgaatcttt tgctcacaac
    21901 cttattcatg gtgccccggc ttgagctgat agatttttga aggacggccg attcctacag
    21961 gacgttcacc gatctcatcg aaatattgga gcatagcttt cttaaaattg gaatgatcga
    22021 tcgttttata atcgatccct aagaatttag caaatacttt tcgagcttcc gtaatcgtga
    22081 aatctttacc taaaacttgt agaacttgcg gctcgtgttc cattttattg actacacggt
    22141 tgaatgcttt caagatgatt tgactatggt caaaagccaa agtatctttg ccagaagact
    22201 ctccagtgac taaatcaagc gagatagcca cttctccgct agataaatgg atcttgttac
    22261 tatgacgttc tagtgtgaac cagcgtactt ccttggcatc atctccggcg attagcggtt
    22321 cttctccaat aaaggctaag tagctgactg tgacgaccca gcctcgcgga tctcgattag
    22381 gcgtactgaa tgtatgcagt tgctcaatat tttcttttga aataaccaca ccagtttctt
    22441 cctttgtttc tcttaagacg ctttctccag ttgactcatc cttttggaca aagccaccag
    22501 gcaatgccca tgaatttcga taaggatgcc cttttctttg gatcaacaaa actttcagct
    22561 gatcttcttc tttgttatag cacatcagta cgatatcgac agtcaaagag ggcttgtcat
    22621 attctggacg ttcctgtttt tgataccagt taagaaattc ttcttcactt gctttatgtt
    22681 cataatataa tttttcttct tctttagaag caaaacggtt catctgacca cctccattga
    22741 cagtaaaagt actttttacc ttattgtagc agactctgaa aaaaaaccaa ggatttactt
    22801 gaaaaatcta ggttatcatt taaatatgaa aaataaatgg aagtatgaga ttgaataaaa
    22861 agaaaagcag ataaaacggc aatactttat accgctcttc acgaatggca aagaagccac
    22921 aaataacgat atatacgtca atgataaaac gcaaaatcca agctgctgtc ataaaactgt
    22981 tcaaatgccc atggaggtta aaataaccat acatacgaat ataaaaatag ctgaatatta
    23041 aatgtgctaa tgaaagaaaa gcaatactaa gtgtaaaaaa aagatgtttc ttctgcatga
    23101 ttgttccagt cccttactaa gatagatagt ctttattata ccacgtgtga ggggagaaat
    23161 aaaaagccgt tttttagtag atatgaaaca aaacaaaaac ccgcatttat tcaacctatt
    23221 catcctttta aaggatagat tgaacgtaga tagaagtcgt ttatccagtc tttttcattt
    23281 tgaaaaaaag ctaacagcat gcttttttta tggtatacta gcaaggaaac gaattcgcat
    23341 catgcgataa aggaggaaga gccccgtggc agaaaaggaa actttttata tcactacgcc
    23401 aatctattat ccaagcggca aacttcatat cggcaactcg tatactacga ttgcatgtga
    23461 cgcaattgct cgttataaac ggttgatggg ctttgatgtg ttttatctca ctggagtgga
    23521 tgaacatggt caaaaaatcg aaacaaaagc agaagaacta ggtgtaaaac cgcaagaata
    23581 tgtagataaa atggcggctg atgtcaagaa attatggaaa acgcttgata tcagttatga
    23641 taaattcatt cgcacgacag atgattacca taaagcagct gttcaaaaaa tatttgatcg
    23701 tttattagaa cagggagata tttacttagg tgaatatgaa ggctggtact ctgtttctga
    23761 cgaagaattc tttacagaaa cacaacttgc agaagtgtac aaagatgacg aaggtaacgt
    23821 gatcggtggt aaagcgccaa gtggacacga agtagaattg gtaaaagaag aatcatactt
    23881 cttccgcatg agcaaatacg cagaccgtct attggaatac tatgaagaac atcccgaatt
    23941 catccagcca gaatctcgta aaaacgaaat gatcaacaac tttatcaaac caggattaga
    24001 ggatcttgca gtttcacgaa caacttttac ttggggagta ccagtcaaga gtgatccgaa
    24061 acatgtggtg tatgtatgga tcgatgcatt atccaattat attactgcac taggatatgg
    24121 ctccgaagat gaaagtctat tcgaaaaata ctggcctgca gatgttcaga tggtcggtaa
    24181 agaaatcgtt cgctttcata cgatctattg gccaatcatg ctgatggccc ttgatttgcc
    24241 tctacctaaa aaagtatttg ggcatggctg gctattgatg aaagacggaa aaatgtctaa
    24301 atcaaaagga aatgtcgttt atcctgaaat gcttgtggaa cgttatggtt tagatgcact
    24361 ccgttattat ttgcttcgtg ctgttccgtt tgggtcagat ggtgtcttta cgccagaaga
    24421 ttttgtttcc cgtgtcaatt atgatctggc aaatgatcta gggaacttat tgaatcgaac
    24481 gattgctatg atcaacaaat attgtgatgg actcgttcct gactatgcct cacttgtcac
    24541 tccatttgat agtgaactgt ctacgacggc tgctaacgtt gtcggacgtt accatgatgc
    24601 aatggaaaaa atggaattca atacagcatt ggctgaaatc tgggtgctga tttctcgtgc
    24661 aaacaaatac attgatgaaa cagaaccatg ggtattagca aaagacgaag aaaagaaagc
    24721 tgaattgaat agtgtcatga tccatttagc tgaatctttg cgtatcgcag cgatattact
    24781 tcagccaatc atgacagaaa cgccagagaa gatcttcaat caactaggat tggactctga
    24841 aacaatgaat cttgaaggat tacactttgg cgaatttcct tcaggaacaa aagtagttgc
    24901 aaaaggtaca ccaatcttcc cacgtttaga tatggaagaa gaagttgctt ttattcaaga
    24961 aaaaatgtct gaaggtactc aaacaaacga agatacagtc aaatgggatc cagaagaaac
    25021 agaacttgtt tcaacgaaag aaaaacaaat caaatttgat gtatttgaaa aagtagaact
    25081 aaaagtagca gaagtcatca actgtcaaaa agtagaaggg gcagataagt tgctgcaatt
    25141 ccgactagat gctggagaca gccaagaccg tcaaatcttg tcaggaatcg ctgaatttta
    25201 tcctgatcca agcgaattga tcgggaaaaa agtcgtcatt gtagcaaatc tgaaaccacg
    25261 aaagatgcgt ggacaaatca gtcaaggaat gatcctttct gcagaagcac cagatggctc
    25321 tttacaagta atcgaagcac caaaatccat gccaaatggc tcagaaatcg catagaaatt
    25381 caaagggggt atgacactag ttgtgtcata cccccttttt ccgaaatttg agaagcaatt
    25441 ttcgtaaatt ccttcttatt acttgaagcc aatcatataa tacagaaaca gagaactatc
    25501 caaaataaat cctagaaaaa gaagtacgag cttcgctgat ttttgttaat ttagaataat
    25561 actaatagga atcgtaaaaa cagaaaaaaa gcataatgat aaagggtcgg gcagatttta
    25621 attgattcat ctggtactct tttttattgt ccttacattc ataaagtttg aatgcaatga
    25681 ctttattaca tctatattta tatctaacag tagcgttgat gtgttaatta taagttctat
    25741 cactttatgt tcaattagtt tgtgctctta tatgtgtgat tgaaaatata gataaaaaaa
    25801 caatcatcgg ctttgacttc gatgattgtt ttctttattt tgtaaaaatc ctatcacttg
    25861 attttatggt aaccttttat ttttgtcttc aaacggcttg gtaagagagc agtaagcagt
    25921 gcaaatggga tcgaaaagac ataccagaaa atcgtacgtc cgataccata atgttgatag
    25981 agctttgtca acatcacgtg taacaagatc aaccctaaaa gcaaggagcc agctataaac
    26041 caatgattat cccaatgcat gacttcacta agtgccatca ctccaaaagg atagaaataa
    26101 aaatagatcc cgactaaggt catccgccag ttctttgtaa atgttccgat attcaataaa
    26161 aagaaaatcg ctgaaagcaa aataccgata ggcggaaaaa gcccaaccaa aaaggaatac
    26221 aacatccccc acaagatcat cacaggacct ttgatcaatg caacgattgc gatgaacaaa
    26281 gtcagcaata ttagtttttg tgataacgtt gcaacagtca ttaatccaaa taaaattaat
    26341 gtgaaccaat gccaatggga ctgctgttgt tctttacggg aaaaatcgac ccggttggat
    26401 aaataatctg ctaatttcgg ataagaacgc ttaaaatcca taaactgttc ctccttcgtg
    26461 gaaaaggtag gtttagtata cgaaaaataa aaaagaaata catccgtctt aagagggagt
    26521 ttttcactga aagtggagaa aaaagaatgg taaattaaaa tattctcagt tatactgaaa
    26581 attataccaa atttcaaaga agaaagagga tgggaatgaa aggcaaacta aaacgagaaa
    26641 tcaatctgtt tggcgcatta gctaccgtta tgggaaccgt gatcggtgca ggcgtcttct
    26701 tcaaaactgc tgctgttact gctagtactc agtctacaag tttgacattg ctagcttggc
    26761 ttttgggtgg tttcttaacg atctgtgctg gattgacagt ggctgaatta gctacagcaa
    26821 tcccggaaac tggtggagct gtaaaatata ttgaagctgc gtatggaaaa ttgcccagct
    26881 ttttattagg atgggcgcaa agcttgattt actttcctgc taatattgct gcattatcga
    26941 ttatctttgc gacacaattg acgaacttat tacaattatc taccgattat cttttgttga
    27001 ttgcagtgat caccgctgtt tctgtgacag ggttgaattt gttagggaca aaagtcggtg
    27061 cttctgtaca atcagtgacg ttgattgtta aattaatacc aattgctgtg attgtcatat
    27121 ggggattatt gaccccagga caaggaactg tccagttatt tccaatcgaa gctggaaaag
    27181 atgttacttt tgtcgaagga ttgagcagtg cgttgttagc aacgttgttt gcttatgacg
    27241 gctggttagg tgtcggtgca atggcagggg aaatgaaacg gccggaaaaa gatttgccta
    27301 aagcaattat tcttggtttg agttttgtaa cagtcgttta tctattgatc aattttgttt
    27361 ttttgaaaac tttgccgatt gatcatcttg ccggtaattt gaatgcagct tctgaagcat
    27421 cagacgtcat ttttggagga atcggtggaa agctggtcac tattgggatc ttgatctcgg
    27481 tatacggtgc attgaacggt tatacactaa ctgggatccg cgtgccttat gcgatggctt
    27541 tagaagacga gctacctttc agtaaacagc tgacaaagct ttcaaagaag tttacggttc
    27601 cttatgttcc tgcggttttc cagttagcag tagcttgtat tatgatgagc cttggttctt
    27661 tcgacttttt aacagacatg ttgatttttg tgatgtggct attcagttta ctgattttta
    27721 tcggtgtctt tattttaaga aaaaaagcgc cggaattgcc acgtccatat aaagtaccac
    27781 tttatccaat cgttccgatt attgcgattc tcggtgctat tttcatttta ggtatgacga
    27841 tgatgacgca aacgaaatta gcattgatcg gtataggtgt taccttgata ggtatcccag
    27901 tctattatca aaaaaagaaa aaacgctcag aagagtaaaa tatttcaaca acagacagaa
    27961 aaagtacgaa ctaggtcctc tagatcttcg tgctttttct atttcaataa aacaagttct
    28021 tctattttga tttttgctac ttctgcaagt agtgcttatg tgctaaagta agaatgaaaa
    28081 ggagagataa acatgatatt tgattctcat acccatttaa atgctgaaca gttcaatgaa
    28141 gatattccag aaacgattca gcgagcacaa gaaatggggg taacgaaaat ggcggtcgtg
    28201 ggcttcgata cgccaacgat tgaaaagtct ttgcaattaa gccatgacta tccaaatata
    28261 tacagtatta tcggctggca tccgacagag gctggcagtt atacgaaaga aatcgaaaat
    28321 aaattacaag aacaattgac tttaccaaag gttgtagcat taggggaaat tggcttggat
    28381 tatcattgga tggaagaccc gaaagaagtc caagataaag tatttcgcag acagattgct
    28441 atcgcaaaag aaatgaacct accaatcagt attcatacta gagaagcact tgaagacacg
    28501 tatcaaatcc taaaagaaga agatgttcga gatatcggtg gaatcatgca tagtttcagt
    28561 ggtgattatg aatgggcaaa acgatttctt gacttaggga tgcatatttc atttagcggt
    28621 gtcgtcactt tcaaaaaagc attagacgtc caagaggctg cagcaaatgt accaatcgaa
    28681 cgattacttg tggaaacaga tgccccttat ctggcaccag ttccttttag aggaaagcga
    28741 aatgaaccag gctatactcg ttatacagta gaaaagattg ctgaacttcg gaatcttccg
    28801 acagaagaag tggctgccca aacatggaca aatgcgcacc gattatttgg tctaagcgaa
    28861 catggataag atgaagatcc aagagattat agtcgttgaa ggaaaagacg atacaagaag
    28921 gctgcgggaa gtagttgatg cagatacgat agaaacaata gggtctgcaa tcaatgaaga
    28981 gatcctgatg caaattgaac atgcccaaga gactcgtgga gtgatcgttt ttaccgatcc
    29041 tgatttttca ggagaaaaaa taagaaaaat cattatggaa gctgttcctc aggcaaaaca
    29101 tgcttttttg ccgcgcacac aagctaaacc aaagaaaaag ggaagccttg gtgtcgagca
    29161 tgcaagtgat gctgctattt tagaagcatt gaaaaaggtc gtgacgccag acatttccca
    29221 aacggctgtt tctgaaatca ctagacaaga ccttttagac tatggtttaa tagctggggc
    29281 acaagcaaaa gaaaaacgag aaaaactagg tgacgagttg cgcatcggtt acacgaacgg
    29341 caaacaattg gaaaaacgtt tgaagatgtt tcgtattacg ccgaaagaac tcgcccaagc
    29401 aatgaaaata gtggaggaac aacatgagtg aatatcgtga aattgcgaca ccctctagaa
    29461 caaaagagat tttattgaaa catggttttt catttaaaaa aagtttagga caaaattttc
    29521 tgactgaacc aaatatttta aggaaaatcg tagaaactgc gcaaatagat gaacatacga
    29581 acgtgatcga agttggacca ggaatcggtg cattgacgga acaattagcc aagcatgcaa
    29641 aacaagtcgt agcatttgag atcgatgatc gtttgatccc tgtattggct gatacgatgc
    29701 aaccctatga caatgtgact attgtacatc aagatatttt aaagaccgat ttgtcaacag
    29761 ctgttagaga aacatttcat gaggagcttc cgttaaaagt cgtagcgaat ttaccttact
    29821 atattacgac accgatcatg atgcattttc ttgaatcaga tttggttgtg gatgaactag
    29881 tcgtcatgat gcaaaaagaa gtagctgatc gtatctctgc tgaaccagga acgaaagctt
    29941 atggttcatt atcgattgct gttcaatatt atatggaagc cagtttagca ttcatcgtac
    30001 caaaaacagt atttgtccct cagccaaatg tagattcagc gattttgaaa ctgacaagaa
    30061 gagatatacc ggcagtcgaa gtgacagacg aaaaagcatt tttccgattg acaaaagcgg
    30121 catttcagca aagaagaaaa acgctttgga ataacttgca gcattcgtat ggcaaagatg
    30181 accagacaaa agcatggtta gcaaaaagct tggaaacagc tggaatcgat ccaaaacgtc
    30241 gtggggagac tttgtcatta caagaattcg ccgcattaag caatgcgatg tcagaaaata
    30301 tgcagtaaaa aaagaggttg tgacagaagt tgtgaaaaag ctgtcctgca tcaagtaata
    30361 agaacagcca aacaaaaata gttcctcatg tttttcgttt gtttgggctt attaccgcag
    30421 atgcaagctt ttgaacaccg tttaagaaag aggttgtggg cctgccgttt aactctaagt
    30481 cacaaggaac aatttcaaaa aacagcttct catgtttttg agttagttgg tcttattact
    30541 tgatgcaagc ttttgaccac tattatgccg aacaaggaga tgtgacacaa attttgtcac
    30601 atctcctatt tttgtttctt gatcaaaaaa ttcttatact tgatactcac actcattttg
    30661 tatggattta gaaaagaata tgtgtcttga cagttattag taagtgagtt atactaagtc
    30721 gacatttatg tgtcaagaca tattaggaga gagaaaaaat gagaaaaaat tcagttcgaa
    30781 aactaacgat ttctgcttta ttgattggga tgggggtcat tatcccaatg gtcatgccta
    30841 aaatcatgat tccaccagct tcctttactt tggcgtctca tgtgccatta tttattgcga
    30901 tgttttttac accaggagtt gcagtggctg ttgcgctagg tacgacattt ggtttctttt
    30961 taacaacgcc ggttatcatc gcattgcgag cattgtcaca tcttgtgttt gcgttgattg
    31021 gggcttggta cttgcaaaag catccgagta tcgttttaaa aaatggacag tttacttttg
    31081 ctaattggcg tttccaaggg ttcaattttg tgatcggtgt gattcattct ttagcagaaa
    31141 tgctagtagt cagcatcttt tactttattg gtaatatgcc tgaaacatat tattctcaag
    31201 gatattttta tacagtattc atcttgatgg ggattggtgg gcttatccac agtttagttg
    31261 attataatat tgcttatttt atagcaggaa cactcagcaa atattttgat atccccgtat
    31321 ttacggcagc aaaaaaagaa aatcggaaag agtcgattca agggtacgcg aagaaaacga
    31381 catattagac atgatctctc aaaaaaaaaa ctctcatcta gtaatggata ataaatcctc
    31441 taagatgaga gttttttgtc ctaaaaagag ctgcaccaac atcttctggc acagctctaa
    31501 cagggggcaa tttatggaag tttgatgact tgttctgttt ctttatcaaa gaagtggcct
    31561 ttgctgatgt tgaaggcaag gtcgactatt tcgcctggtt tatggaaatc tcttgcatct
    31621 acttttgaga tgaactcagt agaaccagtt tttgtgtaaa gcatcgtttc agctccaagt
    31681 aattcggaaa cgacaacttc tgatttcact acggcttcag gtgaagcttc aagggctact
    31741 tgttcactgt ggatgtcttc tggacgaata ccgaagataa cttcttttcc ttcataacct
    31801 ttttcaacta atactttgtt ttttccttca ggaatacgaa gcttaagccc atgtccatct
    31861 gtgataacac catttttcaa tgtcacatta aagaagttca tggcaggaga tccaataaag
    31921 ccggcaacga acatattgac gggtgtatca taaacttctt tcggtgtacc gatttgttgg
    31981 ataaatccgt ctttcatgat aacgattcgg tcagccatag tcattgcttc tgtctgatcg
    32041 tgagtaacat agatggtcgt tgtttcaaga cgctggtgaa gtttggcaat ctcagcacgc
    32101 atggctacac gtaatttagc atctaaattt gataatggct catccattaa gaagactttt
    32161 gcatcccgaa cgattgcccg tcccaatgcc acacgttggc gttgtccacc agataaagca
    32221 gctggttttc gtttcaagta ttctgtcaga cctaagatct ctgctgcatt gtccacacgt
    32281 tttttgatgt ctgctttatc atatttacgt aatttcaagc caaaagccat attatcaaaa
    32341 acagtcatat gaggatacaa tgcgtagttt tggaaaacca tggcaatatc acggtcttta
    32401 ggtgccacgt cattcatgac ttttccgccg atatttagtt ctccttcaga gatatcttcc
    32461 agtcccgcga tcattcgcaa agtagttgac tttccacaac cggaaggacc aacaaaaacg
    32521 ataaattcac ggtctttgat tgatagatta aaatcagtta cagaataatt ttctgcattg
    32581 tcatattttt tatatacgtt tttcagagcc atttctacca taatacgttc cacactttct
    32641 tttttagttt tattaactat ttaaagtata aatgaaagcg ttaactaact tcaatgtcat
    32701 gttgaacaag aattttttct tttttttgtc aatgtgctag ttttaagctt taataaatat
    32761 ccataagaaa taaaaactga tacactggag taaataagta tgttaacaat atcaaaagga
    32821 gtgtctctta tgaaaatcgc tttgatcgct catgaccgaa aaaaacctat gatggtgaaa
    32881 ttagcaacag cgtataaaac aatattggaa aaacatgaac tttttgctac cgggacgact
    32941 gggcagagga tcacggaagc aaccggcttg ccgatccatc ggtttaaatc cggaccgtta
    33001 ggcggggatc agcaaattgg agccatgatt tcggaggatc agttagattt ggtgattttt
    33061 cttcgagacc cgctggctgc acagccccat gaaccagatg taacagcact tatccgttta
    33121 tctgatgtct atgagattcc gttagctacg aatatcggaa cagctgaggt gctactaaga
    33181 ggactggaag ccggcttcct agattttcga agaatcgtcc atgaaataga caagcatcca
    33241 ctttcatttt gatggataag cgtatggaaa aataacgttt aatgttcgcc tatatgtagc
    33301 tataaaagct aaacaaactg ataatatgcg atataatacg aacgtattgg ataatataaa
    33361 caataatatt agtttttcgt atttgcagta aatgtgaaaa tatgctatag tttctgtggg
    33421 aaaagatccc aaaaataata cagagtagaa aataaagcgt taagtgctaa gaggatggga
    33481 tgttgcctct tggacgaagg acgtaatgtt cgcggtttta ttttcgcatt cgctgcatga
    33541 tacgatgtag cagctcttaa aggagatgct aaaaatgaag aaacaccggt tagacgcacg
    33601 tatgattgct attatgggct tattgattgc attgatggtc actttgtccc gactggtagc
    33661 aatcgagacc ccatttatta aaatcagtgt cacatttatt ccacaagtga tcatgggcat
    33721 tctttttggt cctttttggt cagggatagg cgcagtttta gctgatttag taggaatggc
    33781 cctcttctcg aaatctgcat tctttattgg atttacattg aatgcattta ttgaaggagc
    33841 aatctacgga ttctttttct atcgaaaaga gatcacttgg aaaaatgcca ttctggctac
    33901 gcttagtgtc acgctgatca tcaacttatt tttgacacca ttatggcttg cgttgatgta
    33961 ccatgtgcca ttgttcagct gggtcgtttg ggcgccccgc ctgttaaaaa cagtaatatg
    34021 gttaccgatt caatcaattg ccatttatta cgtaggacgt agtattcctt acaaaaaaat
    34081 tttaagaagt ttagcgatcc acgctaaata aaaaacaagc agtcttccca tcccagaaga
    34141 ctgcttgttt ttattgtgct gtgaattgtg cttgatagag ccgtcggtaa taaccatctt
    34201 tttgaagcag ctcatcatgg gtgcccattt cgacaatagc tccctgatcc atcactaata
    34261 tctggtccgc atttttgatt gtggacaggc gatgggcaat cacaaaactg gtttttcctt
    34321 ccatcattgc taagaaggct tgttggattt ttttctctgt caatgtatcg actgagctgg
    34381 tagcttcatc taagatcaac atagggggat tactgatcat cgttcgagca atcgtcaaca
    34441 gttggcgttg tccatctgat atctttaacc cttgaccgcc aatcttagta tctaattttt
    34501 ccggcaaacg ttctacaaat tcatacatat aagaggcttt tagggcatca ttgatttctg
    34561 cgtcacttgc ttccggattc ccaaaacgaa gattttctcg caatgtactg tcaaatagcc
    34621 aagtatcttg taacaccatt ccaaaacttt tacgtaatgt atcacgttgg atagagcgga
    34681 tgtcatggtc atcgactgta attgttcctt ttgttgtgtc ataaaaacgc atcagcaaat
    34741 taacaagtgt ggattttccg gcccctgttt ttcctactat agcaatggtt tgacctggat
    34801 aagcagtaaa attgaaatct tcgatcaaac gctgcttggg gtcataagaa aaagaaacat
    34861 gatcaaaaga gacttttcct ttgatatttt tgggttccaa ggcataggca tctggcaaat
    34921 caggcttttc ttctggctga tcgatcaaat caaatgctcg ttctagacca gaaaaagcgg
    34981 tttgcagttg tgtcgtgatt ccagaaagtt cgataaatgg tttagaaaac tgacttgagt
    35041 agatcgtaaa gctggaaatc acaccaacag tgattgacga accactcttc aatgccaata
    35101 ggccgccaac taaaccaatc gataaataag caaggtgatc tacaaaacga gaagacgggt
    35161 ttgtcaagga agaagaaaat tgtgcccgtt gtcctttttc atatagatca gcatttagca
    35221 gttcaaattg ctgttgacta gcttcttctt gctgaaaagc tttcacgatt ttctggttac
    35281 cgattcgttc ggtcacaaag cccgagatat ccccaataat cctttgctgt ctatcgaaat
    35341 ttgtttgtga agcacgagca acgatccaac tcacaaggaa aataattggt gtagaacaaa
    35401 gaacgaccaa tgtcagaagt ggacttagac gcatcataaa aataaacgaa agaatgatga
    35461 ttgccactcc agaaaataat tgattgaagg ccgcagaaat tgcaatggaa atattgtcca
    35521 tatcatttgt aaatcgactg acgatatttc cgtgggagtt ttgatcataa taacgaagtg
    35581 gcaatcgatt cagatgagca aatgcatctt ttcttaattt tgcaacggat aagtaagcta
    35641 accgattgct taacacttgg atgagccatt gactgactac gttgattaaa acgataccac
    35701 cgaatagaat aagtaaatgg aacagtcgat tgaagcggac ctgtccttct ccaatcattt
    35761 gatcgatact ttgaccaatt tgtaacgtca tcacaactgt tgcaatccca ttgatgattc
    35821 ctagtatcac agctagccaa atgtcttttg cataggcagt aaggtaagga atgaatcggc
    35881 ggagcgtctg caaggataat ttttttactt tcataactat tcttcctcct gtgatgcgac
    35941 gatttcctga tattctgctg attgagcaag taattcttca tgggtaccct gagcagcaat
    36001 cttaccttga tccatcacta agatatgatg tgcttcttga atagagcgga cacgttggga
    36061 gataataatc actgtactgc caagataagt ctgtagcgcc ttacgcaaat ccaagtctgt
    36121 ttgataatcc aacgcactta aagagtcatc taaaatcagt aatgctggct tggcaatcaa
    36181 agctcttgca atcgtcagtc gctgtttttg tccgccagag aaatttttcc cattttccat
    36241 gacttttgta tctaaaccat ttggaagctg acggacaaat tcttctgcct gagcgatttt
    36301 cagagcttcc caacattctt tttctgtggc gtctttctta ccccattgaa ggttttcacg
    36361 aatagtcccg gtaaatagta cagaagtttg gggaacaaga gcaatttgct gacggagatg
    36421 atccagctgc caagaacgaa catccattcc gtccattata actgtaccgg aactgacatc
    36481 atagaaacgc ggaatcaatt gtgtcaaagt cgttttcccg cttccggttg gaccaatgat
    36541 tccaaggact gtatttcgct tcagctgaaa tgtaatattt tggagagaaa gaccagaatc
    36601 aggagtataa cggaagtcaa catggtcaaa agcgataatt gcttcagaag aaaaatcggg
    36661 agtagtactg acctcagctt caagaatcga attttctgtg tctagcacct ctttcacccg
    36721 atttcctgaa gcttcggcac gtgtgaagat cacgacgagg tttgaaacaa cgatcagtgc
    36781 caaaagcatt tgattcatat aattgatcaa agcaagaact tgtccttgtt gcaagctacc
    36841 aatatttact ttgatcccgc caactgtcag caaacagatg atcccgacat tcatgatcaa
    36901 ggttgtagca ggtgataata gggcagagat attggaaaca cgtaaataat tgttcgctag
    36961 atcatttgtg cttttatcga acttctctgt ttcttttttt gtctgcgcaa atgcgcggat
    37021 gacacgaaca ccgctaagat tctgactaac gtgttcattg agctgatcta gtttttcttg
    37081 cactttttgg tagagaggaa cggttttttt gatgataaaa aataaaatga ttgagaaaat
    37141 aggcaataat gctaagaaaa acagacctac ttcccagtcg atcacaaaag ccatgaccac
    37201 tgacccgata cttaaaaacg gtgctctgat caataaacga atgaccattg ctaaagctag
    37261 ctgaagctga ttgatgtcgt ttgtcattcg ggtgatcaag gtatctgttc caaaatgatt
    37321 caactcgttg tgagagaaag tattgatttt tttgattagc tgattacgta actctgtacc
    37381 aaatccttgt gaagctactg aagcatagta ttggcaaatg atagcacaaa tcagaccaat
    37441 cacagacata gcgaccatcc ataagcccat ttcaatgatt tttcctcggt cattcatttt
    37501 tagtccatta tcgatcaagg aagccatcat taaaggcagg acaagttcga agacagcttc
    37561 aagaaatttg aagaacgggc ccaaaatgat ttgcttacga tagtcttttg cataacgtaa
    37621 taactgaatc atatgattcc tcctattatt tatttgtcca caattgaaaa aacaagtact
    37681 accacattgt agcttaggaa atttagaatg aaaagagaac aagccttttc ataaatgaaa
    37741 gttttattat gaagaagctt tagaaattga atagactatt ttttttaaaa aaaagaaaat
    37801 gagaaaacat gccagtctct tcattcatag gaacgtctat tttacttaat ttttctataa
    37861 atgaattctg cataaaaaat atatcaagta aatgtttata gatgaaactc tatttacttc
    37921 ttttttaatt tgttcttgca atcttttttg ctacgtaatt tttgtaaaaa agtgggttga
    37981 gagaaatcta attgattttc aaagaaggag tatgaaaatg agaaaaatat ttattcgttt
    38041 attgtgggta ctatcttaga ggaataaata atagtggaga aaactatggt ttggcgcaga
    38101 ttctatcagg tttgatggaa cgaagacaac ctcccgacat caagtcaaaa gctacttgag
    38161 attttgatct gaaaataaaa aaagaaaaca aggtaggaac atcaatgttt ctaccttgtt
    38221 ttcgtaatca atgggaaaaa actaagagtg gtgtacgtaa tcaataaaaa ggatggtgac
    38281 aacagtacct ctttactctc tgaaagcatc ataactcgtt tttcctcatt atgccaataa
    38341 attgttgtta taccacatat aaggatttgt aatagctaaa aacagacagg aaagttgaaa
    38401 tctgtgaatc ttattttgta tggaaggatt tatagaacgc aaaaatcaag ataaagatga
    38461 ataaaaatcc tgtttcggct atatattgcg tatctacgcc aataaaacga gtttgttctg
    38521 tcatagccat ataaagcaaa ggcaaaaata caactacagc gagataagat ccgatgattt
    38581 ctcgaaaagt tttccaggaa gtatgtttcc tgtttttata tttatccgat ttcattgaat
    38641 agtcatagcc tccttattct ttcatatgtt gaaattccag tataaaaact ggaaggaact
    38701 gtacgttttt tagaataaaa attataaggg ataagtaggc tgctgtctat aataagatat
    38761 atttttcaat tctttattaa agattttatt gacaaaatga atccgttttc tatgatggag
    38821 gaggggtgaa taagttgttg aagaaggaaa ttttatgtta cttagagaac cagacagcct
    38881 ttttcgattt agaacatatg aacgaggtct ttacagcaca aaggttagct gatcattttg
    38941 gggtaaaaag aaacacagtc agtcattatt tgaaccagtt aaatgatgag caactactag
    39001 tcaaaatcaa ttctcgacca gtgatttatt tccacaaaga agcttttgaa aaacaatttt
    39061 ttaagttacg cacgaatttt tatttttcta tcgatgatct caaagaggaa cagccttttt
    39121 tcgcgcaacc aaaagactta ttctctttta tgatcggata cgacgccagt ttgaaagaaa
    39181 gtatcgaaca aatcaaaaca gctctttact atccagatgg cggattacca cttttgatta
    39241 caggcgaaag tggcacaggt aaaagttatt tagttaattt ggtctatcag tattgtctgc
    39301 ttcatgatct gctagaagat tctgcaccat tcatcacttt taattgtgca caatatgcag
    39361 ataatcctga acttttgact agcaatttgt ttggacatgt taagggagcg tacactggtg
    39421 cagaagaaaa taaaaaaggg gcttttgaag cagcagatgg tgggatcttg tttttagacg
    39481 aggtacatcg cttaacacca gaaggtcagg aaaaactgtt cacctatctt gatcaaggtg
    39541 tgatttatcg tatgggagaa cctaatttgt cacgccggat caaaacacgt ctcttttttg
    39601 ctacgactga agagattact agtcatttct taacaacttt cattcgaaga atacctatcc
    39661 gaatcgaact acctgcactt aatcagcgta gtcgtaatga acggctagaa ctgatttact
    39721 ctttttttct cgaagaacaa agaaaaatgg ggagcccttt gtcagtcagt ggaccagctt
    39781 tgtcactttt aacaagtcag aaattatccg gaaacatagg agagctgaaa aatatcgtca
    39841 aagtttcagc agcaaaagca tatgctgaac agcgtgaaca gcctgaaatc catgtcacga
    39901 tccatcattt gcaaaaagaa ctacttgcgc agcctattac taaaaataca gcacagcaag
    39961 gaatctatat tacgcaagac cagaccttag agcaattaat ggagaagcaa cagcccgaac
    40021 agcagcgaat cgttaaaagt tttgagcaaa tcctaattga tttcaagaaa aataactgtc
    40081 tgctatattc ttgcgaagta aaattaaagc aagaagtgat tcaattattt gattttttgc
    40141 tgtttgagac cagtagacaa gaaaaacacg agctgctggt ttattggaca caatctatcc
    40201 gagagacctt tcgacaaatg gaaactgcct atcaaatcaa attcgatgga aacagtgtct
    40261 atgccttgag ttactatctc tatcagcgaa gcactatcaa atggttaccg gaagaacatg
    40321 atattatcca actaatcaaa gaattagaac aacaagtttc tcagtcttat ccatctagtt
    40381 atcactatgt ccaacgaatt ctggaattaa gtaagatcaa attagatatt gaagacacaa
    40441 gtatggatcg gattttactg acgatctatc taaaaaaagc gaaatggtca aaagaaaaac
    40501 gactgccaaa agcgatgatt gctgctcacg gttatgcaac tgctagcagt atggcaaatg
    40561 tagtaaatcg tttattacaa gaggatctat ttgaatcatt tgatatgcca ctagatgtca
    40621 caccacagca gattgcttca gaaatccttg attattgcga aaacagcgat gtttcaaatg
    40681 gattgatcat attagtagac atgggatctc tgaaagaaat ccatcagttt tttaaaaaac
    40741 agttatccgt accgcttttg attttgaata atgtgacgac acctttagca atcacagtag
    40801 gggaatgcct gcaaaaaaat gtatcattag aagagatagc agaagagact gttcgacaga
    40861 tccagccaga atggcgactg ctctatccag aggaaaacaa acccaaagca ctcattacta
    40921 cttgcttcac tggaatcggt acggcggtcc acttaagtga actgctagaa aaaagcttac
    40981 ctacggcttg tcagttgaaa atcatcccat atgaatatca gcaattaaaa gataagaaaa
    41041 acagtgaccc attattttcc atatacgaag tcgtaggaat gattggcacc acagatcctg
    41101 atatcaccaa tatcgactat ctttcattag aagacctcat ctcgggggaa aagatgtctg
    41161 tactagctga atggttggac actactatga atgcttcaga gaaggaaata ttcaatcagc
    41221 gcatcattcg taatttttca ttggaaaaag tactggattc cgtgactatt ctagatacag
    41281 agaaggtgat gggagaaatc gatcatttta tgagagaatt agaggtgcag ttgaatcgaa
    41341 gcatcagcaa tcccaaaaaa ttagcgttgt atgtccatgt gagctgtctc attgaacgat
    41401 tgatccgaca aatgccaatc gaaacctatc aaggattaga gaaatggaag cagtgtcaaa
    41461 aagaagggtt atctgctatt aaatctgcgt ttagtgtcat tgaagagcat tatagtgtca
    41521 tgatccccaa ttctgagatt gcctatatct atgatatttt gagtgaagat acagagtttc
    41581 tctcgataga agaagaattt tgaacataag caagttgttg ccact
//
LOCUS       DAIGTA010000021        41168 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.021, whole genome shotgun sequence.
ACCESSION   DAIGTA010000021 DAIGTA010000000
VERSION     DAIGTA010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.021"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(611..928)
                     /locus_tag="NOB43_001157"
     CDS             complement(611..928)
                     /locus_tag="NOB43_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0982031.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(929..1183)
                     /locus_tag="NOB43_001158"
     CDS             complement(929..1183)
                     /locus_tag="NOB43_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0982032.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(1443..1583)
                     /locus_tag="NOB43_001159"
     CDS             complement(1443..1583)
                     /locus_tag="NOB43_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin RelE"
                     /protein_id="HCI0982033.1"
                     /translation="MYRVAYEIQENKVIPVLLYGTHNNFYELAENTRNFIRVDESASV
                     EL"
     gene            complement(1927..2121)
                     /locus_tag="NOB43_001160"
     CDS             complement(1927..2121)
                     /locus_tag="NOB43_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982034.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(2221..2307)
                     /locus_tag="NOB43_001161"
                     /pseudo
     CDS             complement(2221..2307)
                     /locus_tag="NOB43_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            3473..4513
                     /locus_tag="NOB43_001162"
     CDS             3473..4513
                     /locus_tag="NOB43_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0982035.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            5337..5669
                     /locus_tag="NOB43_001163"
     CDS             5337..5669
                     /locus_tag="NOB43_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HCI0982036.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            6260..6589
                     /locus_tag="NOB43_001164"
     CDS             6260..6589
                     /locus_tag="NOB43_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982037.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            6576..6917
                     /locus_tag="NOB43_001165"
     CDS             6576..6917
                     /locus_tag="NOB43_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HCI0982038.1"
                     /translation="MKNYDPNSRWGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            7031..7270
                     /locus_tag="NOB43_001166"
     CDS             7031..7270
                     /locus_tag="NOB43_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982039.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            7337..7576
                     /locus_tag="NOB43_001167"
     CDS             7337..7576
                     /locus_tag="NOB43_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982040.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKKSSNCQLLLEVS"
     gene            7662..8333
                     /locus_tag="NOB43_001168"
     CDS             7662..8333
                     /locus_tag="NOB43_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI0982041.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            8386..10362
                     /locus_tag="NOB43_001169"
     CDS             8386..10362
                     /locus_tag="NOB43_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0982042.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAVKNAEGKYYGGLVDTDKDGVKEAVWVDNVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTEDIAFKVNKNSFKEENRITVKNNQKAAI
                     PLTGSNGFQTYVLISCLLLGAGGLSAVVYFKKKA"
     gene            10375..11130
                     /locus_tag="NOB43_001170"
     CDS             10375..11130
                     /locus_tag="NOB43_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0982043.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            11127..11951
                     /locus_tag="NOB43_001171"
     CDS             11127..11951
                     /locus_tag="NOB43_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982044.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQPVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            12253..14352
                     /locus_tag="NOB43_001172"
     CDS             12253..14352
                     /locus_tag="NOB43_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0982045.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVLDGKNYDGALWYVEANGTWKKADTGGKLTVSSNTVTYTASDSFLANA
                     ANYGRDYILQLHMKAKNDAKGIAPNVATVTFNNDPNKGTQRTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIALDHYKQFSIQDPVEA
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(14390..16447)
                     /locus_tag="NOB43_001173"
     CDS             complement(14390..16447)
                     /locus_tag="NOB43_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HCI0982046.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNHEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKASQAQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(16561..16773)
                     /locus_tag="NOB43_001174"
     CDS             complement(16561..16773)
                     /locus_tag="NOB43_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982047.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            16960..17427
                     /locus_tag="NOB43_001175"
     CDS             16960..17427
                     /locus_tag="NOB43_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982048.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            17424..17666
                     /locus_tag="NOB43_001176"
     CDS             17424..17666
                     /locus_tag="NOB43_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HCI0982049.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            17684..17986
                     /locus_tag="NOB43_001177"
     CDS             17684..17986
                     /locus_tag="NOB43_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982050.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            18057..20111
                     /locus_tag="NOB43_001178"
     CDS             18057..20111
                     /locus_tag="NOB43_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982051.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGSLDYQISEGFYPTLIDLIR
                     LDIFKDTDETMSVEESYRNEKILQVLEEELESDQRKVNQVSEVEANEEVPWERPIFPK
                     DESKEKEKGIIDEQADILTHKSIFEEENEVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEDPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLRISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQAQIPKWKKEYEIHQQELKEQEEKQRKKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLTHPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            20111..21943
                     /locus_tag="NOB43_001179"
     CDS             20111..21943
                     /locus_tag="NOB43_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HCI0982052.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNSVTCLA"
     gene            22656..24554
                     /gene="ltrA"
                     /locus_tag="NOB43_001180"
     CDS             22656..24554
                     /gene="ltrA"
                     /locus_tag="NOB43_001180"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI0982053.1"
                     /translation="MTNTKGISLKNKQLRHAEYYDMTETFDELHAMSVAKSNFKNLMK
                     FIIDDNNIFLAYRNIKKNKGSATAGYDGVTIKDIEKLACGDFLTIIKRRFKDYRPRKV
                     KRVEIPKPNGKLRPLGIPSIWDRIVQQCILQILEPICEAKFNKHSYGFRPNCSTENAI
                     ADCLARINQSKMNYVVDIDIKGFFDEVNHTKLMRQIWTMGIRDKQLLVIIRKMLKAPI
                     VMRNGNVVFPTKGTPQGGILSTLLANICLNEFDWWIANQWEERTVKELKHHYRKNGAW
                     DKGNIYSKLRSHTSLKEMYLVRYADDFKIFCRTGEEAQRAFYATQKWLRERLKLPISM
                     EKSKVTNLNKAESEFLGFSIRLHKKGKKKVAFTYVCRKAEENIKNKLKQQIKKIQYAG
                     AKKNRHRAIGDYNMMVIGIHNYYRIASHCSVNFTEIYRSVRTVIEARLKARGMTKNGI
                     YGQDHEGYRPYLKSKQMRYIEGFPILPIGYIKKRTPLNKRRNLNKYTKEGRKLIHQEQ
                     QAIESWKIKYLVKGFSNNKKYTVEFSDNKISKFISQKGKCAITGNELLMEEIECHHIN
                     PYHLSKDDSYKNLVIISREIHRLIHATSEETILKLLRLLKLNHYQIRKLNTYRKKAAN
                     FPISIKMN"
     gene            24671..25471
                     /locus_tag="NOB43_001181"
                     /pseudo
     CDS             24671..25471
                     /locus_tag="NOB43_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            25468..27999
                     /locus_tag="NOB43_001182"
     CDS             25468..27999
                     /locus_tag="NOB43_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982054.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            28051..28383
                     /locus_tag="NOB43_001183"
     CDS             28051..28383
                     /locus_tag="NOB43_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982055.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            28384..28977
                     /locus_tag="NOB43_001184"
     CDS             28384..28977
                     /locus_tag="NOB43_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982056.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            29140..30834
                     /locus_tag="NOB43_001185"
     CDS             29140..30834
                     /locus_tag="NOB43_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HCI0982057.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLLKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            31522..33399
                     /gene="ltrA"
                     /locus_tag="NOB43_001186"
     CDS             31522..33399
                     /gene="ltrA"
                     /locus_tag="NOB43_001186"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI0982058.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            33530..33907
                     /locus_tag="NOB43_001187"
                     /pseudo
     CDS             33530..33907
                     /locus_tag="NOB43_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            33966..34229
                     /locus_tag="NOB43_001188"
     CDS             33966..34229
                     /locus_tag="NOB43_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component,
                     AbrB family protein"
                     /protein_id="HCI0982059.1"
                     /translation="MLVKEIEMKKWGNSQGIRFGKEELSVLGETNTENLKFEMVVTEG
                     KIVLTPKNKKPETLDELFANYEGEPLGKEDKYEWGNMQGREII"
     gene            34229..34564
                     /locus_tag="NOB43_001189"
     CDS             34229..34564
                     /locus_tag="NOB43_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0982060.1"
                     /translation="MKKNYHDLSQGDLVYIDLNPTKGHEQRGKRPCIILSKPNKYLNY
                     MIGVAPITTKAKPFPVHVDLNGTQKIKGQILLEHHRMIDIESRGFQFVEAVPKEILEE
                     CIEKIKLFY"
     gene            34638..35840
                     /locus_tag="NOB43_001190"
     CDS             34638..35840
                     /locus_tag="NOB43_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI0982061.1"
                     /translation="MENDTNIVMEHLKRRAKRRLFLWLFGTSAGLITILITVFVTLFL
                     ILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKL
                     LPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFP
                     NSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMSI
                     ITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGGE
                     FRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQ
                     EFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPL
                     PFLNSSKK"
     gene            35856..36500
                     /locus_tag="NOB43_001191"
     CDS             35856..36500
                     /locus_tag="NOB43_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982062.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            36511..37317
                     /locus_tag="NOB43_001192"
     CDS             36511..37317
                     /locus_tag="NOB43_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982063.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTHQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            37339..37569
                     /locus_tag="NOB43_001193"
     CDS             37339..37569
                     /locus_tag="NOB43_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982064.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYLAAKKYFTADNK"
     gene            38127..38405
                     /locus_tag="NOB43_001194"
     CDS             38127..38405
                     /locus_tag="NOB43_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982065.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHALLDYKKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIEQ"
     gene            38444..38866
                     /locus_tag="NOB43_001195"
     CDS             38444..38866
                     /locus_tag="NOB43_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982066.1"
                     /translation="MAKATRKHIYLYDMHIEVLDEIISTHDDISNYSEAVRHLCMMYD
                     PKTEEKISPSQIKLNAIGKEVSILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            38886..40478
                     /locus_tag="NOB43_001196"
     CDS             38886..40478
                     /locus_tag="NOB43_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982067.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTLEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEYGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTEREKIEYQRLNQAMEKYQAEPHKKTSGTLPGVFSISSDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEVGLKAAGRK
                     MMETLFEKEKLNDTGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNSLTKVVKEPVRYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDENRTKLSPYTREKLDELTQYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QTQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            40508..40843
                     /locus_tag="NOB43_001197"
     CDS             40508..40843
                     /locus_tag="NOB43_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982068.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            40984..>41168
                     /locus_tag="NOB43_001198"
     CDS             40984..>41168
                     /locus_tag="NOB43_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982069.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        15039 a         6307 c         8125 g        11697 t
ORIGIN      
        1 tatatttttt accagcaaac catacatatc ttttttcatt aagtatgttc actatctctc
       61 ctccattaat tatatttagc atcaaatagt tattgtacct atattttatc ccattccttt
      121 taaaacaaga atacgtacaa agtaaaatgt tgtaaatagt ctagcaggga agtatatttt
      181 catgtaccaa cataatattt aagaagtttc ccatagatat attggacttc ctcttttaaa
      241 acacaaaaat aaatactacc ttatttaggt agtatttatt aaaagttacg tcaattttga
      301 ttaaaaatat actacttgaa cctctcatga gtaaagtcac gaaatttttg ggaatagagc
      361 gtacttgata tcttattttt tcactaatag cagtgtctct tattcaccaa gcgatccccg
      421 tagttcctac ggttcttaat ttttctctag actaatgatt gtatctttag accttcggcc
      481 ataacatgga gcaaaataaa aaggtactaa gtcttatata tcaatcttcg agtaaccgac
      541 ggttaacaac catatcgagc ggcattaatc acccacctgt agaggatgag cgactttttc
      601 ctaattattg ttaaaagcct agtttcattt gtttagattg gaaaatacgt cctacaagta
      661 tctctttttt ttcatggtcg atccgataaa ataaggcata gcttttgccg atcacgatcc
      721 gatatgttgg gatatccatt ccatagattt cggaaacttc ctcatgcata gttggaaaat
      781 ttttggttag ttctaaagcc ttctggatcg cacctacaaa tctttttatg ctggctggag
      841 aaagagcaag ctcattttcc cattcttcta ttatcgtttc aaggctggtc tggaaacttt
      901 tagaataaac tagcgtgtac tctttcatct attcactcca gccgtatttt ccgaaagctt
      961 ttaccatttc aatttctgaa actgttaaac ctttctcaaa gtcttggaaa ctttcttcaa
     1021 tcaatttgcg atcgtgttct tttgctattt gagtagtatc taatatgaat aagttgcctt
     1081 cttgtttggc ttggatagtg tctccgcttt ttaatccaag agagcttgga aggatcactc
     1141 ccacgctatt gccgatcttt ctaaccttta gttcttttcc catgttatca cactcctttt
     1201 agtttttgat gaataaatta taacatgtta taacaacaat tgccaacggt gtttcttaag
     1261 ggattccact ccatattatt attggacaaa ataagccact tagaacgctg aaaacatata
     1321 caaacgatat caaaatacga gtgaactact caccatacac ttccgttaac atccatttaa
     1381 gtaggtattt ttattatata tagatttaac atatgtcggt cggttgattg atatagctaa
     1441 agttataact caaccgaagc cgattcatct acacgaataa agttgcgagt gttctcggct
     1501 aattcataaa aattgttatg tgttccatat agcaatactg gaataacttt attttcttga
     1561 atctcataag caactctata cacggtgacc gcatacttaa atccattaga tcaattacct
     1621 gataaacctc cagttttttg ctcttactta aatggatcaa tggcaatttc atcacaaacc
     1681 tatagaggat gagtgacttc tgcctaatta cgttaaaaaa tattgaaagt aactctatgt
     1741 agcaaaaaat atctagaatt tcatttcctc aaaactgatc gatattgtat ctaaaaatat
     1801 atactaccta aaataggtag tatatattaa aatatgtgct tttgttagaa aaatcaatac
     1861 ataaattatc atatctgtat atgtcattta ggtatttcag ttatgttata atagttttgc
     1921 tgtctgctac cccggcctaa tctggcaagg ggaggaggag atataatgaa ataccttttt
     1981 gattttgttt ttgcaatcaa gccacttgca gatgtagtgt gcagttacct ctgcaaatgg
     2041 cttgattgca aaattgccaa aaaagacagt aagcctaccc gttaattcta taatatagaa
     2101 acgtaaaaaa aaccccatca gcctgcacgc tgatggggtt tggtgatata atgaaatacc
     2161 tctttgttac tcataattat accataatta gtcacgaatg caaccaatag aaaaaactac
     2221 ttagaacggt agatcatcgc taataacaat gcattgtcca ccaaatggat tttgtgaagc
     2281 attaaataca ttgttattaa ttgtcgctgc ttttaactag gcctctcccc ttctattata
     2341 aaagaagata tatatcattt cttaattacc tactacctta aaccaaaatt taagtactac
     2401 ctaatttaag tagtacttaa acaatctaaa aaatagttat cccaattgtt atgcttttat
     2461 aatacgatta tttgtaacaa aatgaatatt atataattaa acactaccat atttaggtag
     2521 tgtttaatta ttagcaaaac aaaaaatatt tattctattc tcttaacttc aactaagtta
     2581 tgctgcacac ctttatataa atcatatgca actcattagc tagacaaact acaagcatgt
     2641 agttttatct gttaattatg tactacctaa ataaagtagt ttataattag caagtatata
     2701 tatttaaaaa tttaagatta atttttttat gacttgtaca aatttatctg atattctctt
     2761 attaagaact acctaattta ggtagttctt attttttaca ttttaagtag tatttaattg
     2821 caatttggta gtattttttt attatcttat tcttagaacg gtagtactta atataaatat
     2881 aggtagtatc taatttaagt attaatggta gtatctaaat taacaggtag tatgtaacta
     2941 ctttaaagta atttttttca gattaacaca gtagtatctt attaaataag ttaattttaa
     3001 tggtagtaca taattattat atatatctga cattggtagt acttattgta ttttttagta
     3061 gtatataatc tattgttttc tagcctaaag ccttgtctta taagaataat ataatatata
     3121 ctactgaaat aaggtagtat atattactag taatggtagt atgttttata tgcataaggt
     3181 agttcttaat ttattttttg ttttgacact ggtagtactt aattatcttt aattttaaaa
     3241 ctaaatttta ttcatacgtt tttctggtag tatttaatta taaataatat ttatttaaag
     3301 tagttcttaa tgactttaaa ggtagtacat aattcatttt atttctgatt ttaggtagta
     3361 tttaattaaa aaacagtttt aatgcgtttg cattttttat ttatctttgc tattttcgaa
     3421 aagagtaggt aattttacat aaataaaaca acgtgaaagt agaggatcta caatgactga
     3481 ttttaaattt tttaaggcgg atagagttta caacgaatta ttttatcaat ttccaaaagt
     3541 ctttattgtt tctgacgaat acaaaaaaat gaaagattca actaagattg cctatatgct
     3601 tttaaaagca agattagaga tcgcaatcag caaacggcaa atcgatgaag aaggtaatgt
     3661 ttattttact tatacgacaa atgaactatg tagagtatta aactgccaaa aacaaaaagc
     3721 gatagcaatc aaaaaagagt tggaatcctt tggtttatta ttacaaaagc agatgggatt
     3781 taacaaacag ttagggaaaa ataatcctaa tagactatat ctagcagaat taaaagtctc
     3841 agaaaatgat atctacttac tcgaaaaatt tgatagagag aatagggaaa acgttgataa
     3901 atcagagggt atgaaaatca tacccaccct cgacgaaaaa tcagacgctg aatcccttgg
     3961 ggctcaagag ggtatgaaaa tcataccgtg ccaaaacgtt gataaatcag agggtatgaa
     4021 aatcatacca gaacttaata ataatatatt agacactaat agacacaata tagacactga
     4081 aaaagaccgc ctacaagatc aattgttgtt agacaatttt gagacaatta tgacaaacga
     4141 cagcattgct acgtttgtcc ctgaacgagt attaaatttg ataaaaacat tttcttcaag
     4201 ttacagtgaa gctcaaaaaa ccgtccagac tattcataat gcaaagaaaa aagctgaaat
     4261 agaaagtgat atttcgatag tttttgaaga actcgatagt tattatgtca atgcagaaca
     4321 agaattatac acgacactgt taaaagccta tcaaaaatta aaaaccgaaa aagtcgaaaa
     4381 tatccagaac ctgatttttg tctatgtaaa aaattggttt atcgaaaaac caatagctgc
     4441 taaagtatca agtgaaaaac gtttgaatta tgcaagctcc ccaagcacta ttacgaaaga
     4501 ctggttagag tgaaacttta ctgacaaagt gattgttgct tcatggagta acattaaaat
     4561 taaaaatttt ttattattct aattatatta cgaatattac aaaataatag ctattttaat
     4621 agaatttata agttaaaata ttatgataaa aatcacaaac gtagcctttt acgtcataag
     4681 tgttaaaaga aataattaat ttcaaatata gaaaagggaa cgtatgtttg catactcctt
     4741 ttttttgagt tataataata cgcgaagaga gataatttca ttatttaaac aagctaaaaa
     4801 tcttgatatt acttcttttc aggcaatacg aatattattc gcttacattt tttgtataaa
     4861 tttaattgtc tgctatgctt gtgatgaatt gattttcgtt ttgcactttt ggatgataaa
     4921 tttggacaat tgaaaataca aaaaaaagaa aggcggtatg aactcggaag gctggtaacc
     4981 ttcgtcagcg ttcatacacg gcattaagat ttggccctta atgcgttaac ctttcagtgt
     5041 tacggtatta cccgcaatgg atttagtata acagatattc aaaagtgata ccactttttt
     5101 tggctgtgtt aaggttaaaa atacgtgata ttacgatgaa tctatgccta agcataatgt
     5161 tataaaaatg tccgtgtggc tctttgccgt atgacgaacg ctgaaattag agggaacgca
     5221 tgtttggatg cgttccctct tttttgtttg tcatgaacga aaatcaattc tctatttttg
     5281 aaaaataaca agaaaaactt gttaaaaata tttaaagaaa ttgggtggtt tattttatgt
     5341 catatacagg aattttgagt ctcaaagata tttgtcacta cggtaaacgg tgtaccgcta
     5401 cagagaaaat cacgaagaaa ctatcaactg gccaaagtaa aaccgttgtg cagtgtaaga
     5461 aatatataat ccagaaagac aaagtctcag aggaaatgat ttattacatt gggaaacaaa
     5521 agcaaataat tttaaaagat cctatcccct taaaagagct atatccaaca atcaaacatg
     5581 tttatgacca aaacggtgta ctgattggtc gaagaaaaaa tggagtcttg cgttgtaccg
     5641 caaaagggat ggggcgtttg atcggctgaa ttgatcattc tcataacttg tattttatcg
     5701 tttttcgctt gcttgaaaat attgtcgaga cttctaaagg aacttagagt cactagaaaa
     5761 ataaggagta gacttgatct atcaacaatt cccttcgggg agtgacgggg taggttttta
     5821 cgattggtaa cgtaaaaaat tggtcaatcg agtaaatgcc cttgtttgga tagtggtgaa
     5881 atgaatttgt gtaaataata tgcacagagt aaacaagagg gaatttagaa gttagacaag
     5941 ttagaatagc gcctagatta atcatgagca gctactaagg gatctaggct ttgacgcaaa
     6001 ctcatggaat aaggagtagg tcttctcgta atggggagga cgcacaagaa attgtgtcgt
     6061 gtgctgcagt acatgtagat acttgcgaag acgttgatct ttggatcaat cgagcattta
     6121 ccgttttcta ctagggtttc tcgtttcgga cgccataaac gagtcgattt attttatata
     6181 tttttgagtg aacgaaaaac gataaaaata ttcgttatga agtaaaacta atttagtaga
     6241 tagcaaaggt ggtagaggaa tgattcaaaa atttgcgaaa atgagtaaaa ctgcatggat
     6301 tgaaaagctt gaaaatgact tgagtgtcat gcgattagct ccaaagaaat tcaaacgaga
     6361 gattgcagaa aaagaagcaa ttttgtcggt attgaatgcg gtagacgata aatgtccagt
     6421 aaaaattagt ttttcagata tagcaacaat tatcgaaggt atttattatg gtgaagttga
     6481 tgaagagata tcttctacaa aagatttatt agattttttg gataaaaaca aagatacctt
     6541 tatagtacta actgattatg aggaggttac aacaaatgaa aaattatgat ccgaatagcc
     6601 gatggggaac acatacgatt aaggtttctt tccaacgttg ggattacaaa ggatttgtga
     6661 cgtttagaag aggcggaaat tgtaaaggat tagatgtttt agcattagac gaggatgatt
     6721 tatacgatca aacattgact gataatccaa ttggattcgg cttgctacct gaagatgatg
     6781 aaggtaatga atggtttaaa atgacgctta tgaatgataa tggagacgaa ttatctgttg
     6841 aagatacttg gtcatatttg agtgattata ttgtcagcgt tgaaatcatt gaatttgtag
     6901 cggataaaga agaataaaaa ctggaggaat aaattttaca gataaaggct tagaaggagt
     6961 cacgacgatt aataaaaagg tagtattacc ttaggcattg agtaaggaat ttatttagga
     7021 ggaaaattag atggcgcgac cagttttaga ggcgatggat atggatactt tgacaaaagg
     7081 aaggtatgta cagctgttag ctcgtggtta ttcacctaaa gatgtattca aatccctgtc
     7141 taaaggaaca gatatggaaa aagaaagatt acgaaaagaa ttcgattatt ggagaaccca
     7201 taatggaatc aaggatttga aaccagcacg gccagtaatt aaacgaaaga aaaagataac
     7261 ccaagactga agtgtagagc gtatgtgatc ataggctttt ttatttttgc aaaaaacaag
     7321 gaaggtagga aaactcatga attatgaaga aatcgaaaac agaaaaaaag tgtcgaaaga
     7381 aatggaagaa aagttgctaa aaacgatgaa acaaaaacac cttaaaagat tatctgtcat
     7441 gcaatatatc aatgatatgc agataacagg aaaagagaaa gcttgtttgt taggttcaat
     7501 gaaaaacttt gaacagttga gacgaactta tgtgaaaaaa agttctaatt gtcaactatt
     7561 gttagaagtc tcatgacatt cattaataga attcattttt aaaacttttt ctatggaaat
     7621 gagaaaaaga ttttttgttt tgtctgaaag gaggtagctg gatgagaaaa tggttatttg
     7681 gttttttagg agtcgcttta atcgtctttt gcagtgtgtt tggctatgtt agctaccaaa
     7741 aacatgaagg agaggtgttt aagcaaaata tagaaaaaaa gatgcccgta gatcaaatca
     7801 atgcacatgc aaagagttat aaggaggatg caacgaacgt caataatgat atgtctttgg
     7861 ggcaaatgtt gtccatacaa aaagaagcaa tcgaaatggg cgtcaataaa caagtatttg
     7921 cacaaattca gattcctgca cttggtttag cattgccaat ttttaaaggt gcaaatcaat
     7981 acactttgag tcttggagcg gctacttatt tttatgaaga tgctgaaatg ggcaaaggaa
     8041 actatgtcct agcaggtcat aacatggaaa tgccaggtgt tttattttct gatatccaaa
     8101 agttgtcatt aggggaggtg atggacttag ttagtaacga tggcgtctat cgttacaagg
     8161 taacgcgtaa atttatcgta cctgggtact ttaaattaat cgatggcgtt cctgaagaga
     8221 actctttctt gtctttgcca aagaaaggag agaaaccctt attaacgttg tttacttgtg
     8281 tttatacgtc acaaggaaaa gaaagatacg tggtacaggg agagctacaa taacaaggtt
     8341 ttaatcaacg cgagtcgttg aaatatgaaa tgaggagagt aaaaaatggc aataaatcgg
     8401 tatgtaaaaa aagctggaat gcttgttgga atgttaggaa tcattgcagg ctgctttcag
     8461 gggtatcaag tacatgcaga agatgtcacg caaaaaacac caccagagaa ggtcaatatc
     8521 acggttcata aattaatgta cgatcaagga acgcaattga atgttgatat tgacgggatc
     8581 aaaaacgatg gttatacgca cgatcaatat cctacaggtg taacgaaata caacaaggca
     8641 gattatggtg atgttgagtt tacgttagga aatattacgg atcaagtatt accgagagaa
     8701 gattctgatc taaccaacgc gaaagtggac gagattgtac aagatgtaga agacaaggga
     8761 tctaacagtg agtacgtcaa gaatgcaacc aacaaaatta cttcagctgt agatgaaaat
     8821 ggtgagatca cttttactga tcaaccagcc tatgtcaatt ccaaagggaa tgtatatgtg
     8881 gtttatgaaa gtaaatccgc tgctggatta gtcacacaaa aagcaaaacc aatggttgtg
     8941 attgcgccaa tgacagataa aacaggatca ggatttttaa aaaatattca tttgtatcct
     9001 aagaacattg tttctaagtt gagttttgaa ttaacgaaat ttggtgacga tggcgcagac
     9061 caaagcaaac aaaccctttt aaaaggggca aaatttgagt tatacaaggg cgaacctgga
     9121 aaaggaacaa aattgggtga tcttgtatcg gatgatcaag gaaagctgac tgcgactgat
     9181 ttgacgttag gaaaatacta ttttgtggaa gttccttcgg aagttgtagt gggatcagat
     9241 caagaaccaa cagcagatca atatttatta ggcgcagacg ctcgcaacga tgcgcacaat
     9301 aaattaacct ttgaaattac gaatgatggc gtgacaagtg acttaaaagc ttcatacgta
     9361 aactataaag caccagtgat cgataaaaca gtaacaaatg gaacaggaca agaacattct
     9421 ttccaaattg gtgacgcagt aaattatcaa ggaacgattc atattccaac agacattgca
     9481 ggtggcgcag acggtatcac agtaaacggt gtgaaaagcg aaacttctcc ttacagtgta
     9541 tttaaatggg gagatacagc aggacaagga ctttcttatg tcgctgctaa agcaaatatc
     9601 aaagtaacaa ataaagatgg atctgtggta ttaaaagaaa atacagatta taaaatccaa
     9661 aattcagaaa atggctttgt gatcgatttt atcgtgaata atggccaagt aagtgatact
     9721 gtagcaagtt tacacggaca agatcttcaa atgacttata acatgtatgt aaatgacagc
     9781 gcagctgttg ccaatccatt aacaaatagc gtggatttcg tttataacaa caatccattt
     9841 aatcaggaag aacaccacga aaaaacgaaa gctgacgttg tgacttatgg tgcaaaattc
     9901 ttaaaagtcg atagcggact atttggaaca ggaatcaaag caacaccgct tgaaggcgca
     9961 gaatttgctg ttaaaaacgc agaaggaaaa tattatggtg gattagttga tacggataaa
    10021 gacggtgtca aagaagcagt atgggtagac aatgtagcaa atgcagcgat tctaaaatca
    10081 gataaagaag ggcactttga aatcactggt ttaactgaag gtgaatattc attggaagaa
    10141 acaaaagcgc ctgaaaacta tcaaaaatta acagaagata ttgcatttaa agtaaacaaa
    10201 aactcattta aagaggaaaa tcgaatcact gttaaaaata atcaaaaagc agctattcca
    10261 ttaacaggta gtaatggttt ccaaacgtat gtattgatct cttgcttgtt gctaggagca
    10321 gggggacttt ctgcagttgt ttactttaag aagaaagcct agaaggatca gctaatgatt
    10381 attcgtaagc ccccaaaaag aagagtcatg cacaaactga tgatattttt ttggttgctg
    10441 tcggcagtag cagtctattt aattccagtt gtggaaacaa atgtagcgaa atttcaacaa
    10501 cagcaaagaa ttttagccat tgaaaatctt gaaaaaacag attcttcttt ggatgttgcg
    10561 aaaatagagt taggcgatcc tgttggtgtt cttacaattc caagtatttc tttaaaacta
    10621 ccaatttatg acggaacttc cgacaaaatt ttagagaatg gtgtagggat tacggaagga
    10681 actggcgata ttacaggagg aaacggtaaa aatcctttaa tcgcggggca cagtggactt
    10741 tataaagata atcttttcga tgatttgcct tcagtaaaaa aagggcaaaa attctttatt
    10801 aaggtaaatg aagaacaaca tgcctatcaa atttatcgaa ttgaagaagt taaagcagaa
    10861 gaattacaaa aaaattattt agattatctt atgcctgaaa aagaccaaga taggatcacg
    10921 ttaatgacat gcacaccaaa aggtgtcaac tcacaccgct ttttagtgta tggtgaacga
    10981 gtttccttca gtaaagaaga tttaaaacta cagaaaaaag caaaaaatag gaaatcaatt
    11041 tcattggatt ggcgattagc actgctattc gctttttttt gcgttcctat tatttttatt
    11101 tataaaaaaa taaggaggag atcggaatga ataagagaaa atggctgttt gtttgtgtag
    11161 cagctctctt ttctactgta gcttattcgc aactgtcttt cgctgacagc agtgatagta
    11221 gtaccactca aacaatagat aattcaatta ctgcaccaag cgaaacggac agttcggaga
    11281 atactacaga agaaacggca gattcaaata taagctttac tgaatcaacg aatccaacgt
    11341 cagaaagttc ttcagagact tcagaaaagc cgcaagacgt agaagatacg caagtgatca
    11401 agcaagccat tcatattcaa aaaattattt cttcgaatca aatcaacaat caaggcagtc
    11461 aagtagccca gcaagaaggt atcaatggcg caaagtttat tgtctacgat atcacgaata
    11521 tcttagaaga aatgtcacaa gatgataatg agaaaaatca acctgtagaa ataattgagt
    11581 caaaattgaa agatcgagca aaaaaacttt catacgacca gttgaaaaaa gtggctgaag
    11641 gagaaaccaa aacgattgat gatcaggaag gcgtgattga attttccatt gaagtacctg
    11701 caaacaaaaa acaagcatac tatatcgtta atgaatcaag ccctgaaaac atttcaaaca
    11761 gtgaagatat tgttttattg acacctgttt caaatgaaaa aggtgaattt ttgacggatg
    11821 tttggttata ccctaaatca gagaaatcag agccgaaaga agaaattaaa aaagttgtgt
    11881 caactggtgt aaagaagaac ttttttgaaa attgttggga attttttgct caattatttt
    11941 ttgataatta ggatgaaatg atgaaaataa taagaatatt agtttttaat ctatcctttt
    12001 tagccgcaac attattgtgt tgcggtttaa ttttttctca attatcaatt tatccaagat
    12061 atcaacgatt gttcattcat tttctaaaca ttcaatgtgc ttccatgcca ttagaggtga
    12121 ttaaaaagct cttgatcagt ccaattttta tggttagttt ggttcttctt acaggattgg
    12181 taacgtgggt attaggaaaa aaagaatgaa aagcttacga tcgtttaaaa aaaatattag
    12241 atggagggca ttatggaaaa taaaattcat tgcactacgg gaagagtaat tactttagtg
    12301 ttgtttttgt tccttcttct ttttgcgagg ggaactgcag tccaggcctt agaaaaagtt
    12361 gatccgagtc aaatcaaaga aaataataat ctggtgcttt atcatgatag tgattcattg
    12421 agaaatatcg aagtaactgg gatcaatgga tttaagatac tagatgagta ttcaactaaa
    12481 aaacaaaaag tacttgcttg gccaaaagtc aaagatttga aaagtacgtc aaaaatcgtt
    12541 gcccattatc aaaaagtagg tacttatcta ggaaaagaaa ttgattgtga cgtgactttt
    12601 tctaattttg tagcgcacgc tggggttaac caagacggat tagctaaaac aattaatggc
    12661 aaaaagtatt ataattattt gctctttgat aaaaatattt atcgaggatt tttcatgcag
    12721 tcaatcaatg tcatgaatgc aaaactagaa tttaagtatg caggaacaaa aacaaaagta
    12781 gctttgagtg aaccacagcc agaaattcaa tcaaaaatga gatcgatgag agcagctggt
    12841 attgatttaa acgatacatt tctatccatt tatagtttaa atggacagta tcagcaacgt
    12901 gtgtcttggt ataatgacaa taatgaatct gtcggtgaac gtaatattga tatgagagaa
    12961 tttgttgggt atgaaaaaat gggtagctta ccttattttg tcacaacaga tacagcatgt
    13021 gcagaataca aagctcctgc gttatcaaca aacaatttaa cttcaaaagt agtgggagga
    13081 cgtgcagaaa aggcttatag ctcgaatgat catttcaccg atgttgtagg agctgatact
    13141 tatcacagaa gtggtgtaac gtatacgctt caaggcgctt ccccaacatt catgattggc
    13201 gcaaatacga atagtatgat gtttagcttt gatactgcat tgctatggac accacaacca
    13261 tcgaagccta caaaagaagt gtttaacaaa gctaatactg aagaggcagc acacaatatt
    13321 gacaaaaaag tgattccaca aggatcagat gtttactatc atattcacca aaaatttgat
    13381 gcattaacag tcaacacaat gaacaaatac aaatcattta aaatcactga tacctttgac
    13441 agcaaaaatt ttgatatggt attggatggg aaaaactatg atggcgcatt gtggtatgtt
    13501 gaagcgaatg gtacttggaa aaaagctgat acaggaggaa aattaactgt atcaagcaat
    13561 acagtcactt atactgcttc tgacagcttt ctagctaacg ctgcaaatta cggtagagat
    13621 tatattttgc agctccatat gaaagcaaaa aatgatgcaa aaggaatcgc acccaatgtg
    13681 gctactgtaa cgtttaacaa tgatccgaat aaagggacac aaagaacaaa tacagtagaa
    13741 aattatttct ctcttaaacc aaataaaaaa gtggaacaag atgggaaaga tgttgatggt
    13801 cgaaatgatg gtaaaaaagg aacgcctaca gctcctttaa atgcaggatc tgaagtacaa
    13861 tatctagtca cacaaaaatg gcatacaaaa ggtgtagaca ttgcgctcga tcattacaag
    13921 caatttagta ttcaagatcc agtggaagct cgtttgacgt ataaagaagg ttctgcgcga
    13981 gtgatagata tgagtacagg aaaagatatt acttcagaag gtacactaac ctatgatagc
    14041 aattcaagaa cgctgaagtg ggaagcttcc gctgatttct taagtaaaaa tcttttagat
    14101 ggacgagaaa ttcaactgat atttacagct aaaactcctt tgaatgaaga attggatatc
    14161 gacaaccaag caaaagtttc agtagaaagt attgagaaag caactaatgt agtaacgatt
    14221 ggggtaaaac ctaacttacc tcagatcatt gtgccaaaaa ctggatcgaa tcatttagtg
    14281 ctaactgtta ttggaagtat attatttctt actttagcat cattgggcta tgtagtttta
    14341 aaactcaaat aaatataaaa acaaggctga gaatcagcct tgttttcttt tatttgaaga
    14401 ttggattcgc actaataaat acattatcta cgccaattct accagcagag tcaactacaa
    14461 aattatgacc taatccgaga atactttggt tattataaag taaatttgca ttatgggcag
    14521 ggctattttt ccatcctacc atggcatcga tagcaccatc gtctgataaa aggtcatcaa
    14581 tatacagccc agtttgactt atgttttctc ccttagcacc gtagcagcct aagctttcca
    14641 ataaatcttg gaaagtacca ccaccagggc gatagtgact gaagctgact tgtaattctt
    14701 tagctcgaat atctgcagcc tgttgaacaa tatcattgaa ttgcattggg gcaacaccat
    14761 tttgttggcg ataatcattt aaccaagcaa gttctttttg acgcataaag ttacgtaatt
    14821 cgtctaatga aatcttttta tatttgaatg tgattgtttt attttgatcg acgttattaa
    14881 tggatcgttg gccgttttta tccacggtaa cggtaggatc gtcatttctg cacaagaaat
    14941 aattttgatc agtcatgttt ttccaaggag tagcaaagct atccccttcg tatactgttt
    15001 ttgattcact agagagaaca gcgttggtat cagcatttac atgattaaca gtcacattaa
    15061 atttacgagt gtagttgaaa atataatttt gactttcagt cacattgttt aaggttactg
    15121 aatttgttgg ttctacccga tcgtctaaaa catatccttg aatagaagga gcagttaaag
    15181 tgacactgtc accgtgagtg acattgacta tctgttcttt caaaatatta actcgtcctt
    15241 cgtttttgta gttgttattg cacaacaaat tgatttgatg cacttgatta taattgaatg
    15301 tgattgttgt attacctgtg attgttttgc tttgagtatc attaccaatc actttgtagc
    15361 taaaattatc tttagcgcct tcgctatatt taaatgcttt tgccttagca gtgtaagtag
    15421 aaccagaagt tacttttgct tgatctgtag caatcacttg acctgtttga ttgtcaatat
    15481 ggttaatagt aaccgtatat tcttttggtg tttcaggttt gtgttgcaac cctttaaatg
    15541 cagcatcaag actattttta gcattattta cttgggcttg agaagcctta gaatcgtcta
    15601 gtactttttt agcattggat aaagcagtct gaaaattatt ccaagattct tctgtaaaat
    15661 ctcctttagc agttgatttt actcggttgt ataaagcttg taattcagct ttattcacag
    15721 taggaactgg ttttttcttt aatcctttgt aagcagaatc taatttattt ttggcactat
    15781 ccacttgttt ttgagtcgct tttgagtcat ttaacacttt cttagcattg tttaaagcgg
    15841 tttggaatgc gttccaggta ttgtcggtat agtcaccttt tttagttccc ttaacgctcg
    15901 tataaagagc ttctaaagct gatttattca ctttgggttt agaggtgtca gcgccatacc
    15961 aaccgatacc ttcgtatttc cagccatagt ctttggttaa ccattgtact tctttccaac
    16021 ttgcagtgta gtgatgtgag ccagatttta caccaggaag gaaaaggcgg tagatcggtt
    16081 tattattttt ttcggcagaa cgccaggctg gcccttcata agtccagccg taatttttag
    16141 tcaaccattt cacttcatcc caactagctg tgtaatggtg atcacgaaga cctttattgt
    16201 acaaacgata gacaagatgg ccaccgctag tcggtgcttc ccaggcgggg ccttcataat
    16261 ttccccattt tatctttact agatggtcac gttctttttt gctagaggtg taaaaatgtt
    16321 catgattatt tggattgtaa aggcgataca tgacgttagt tgaagcagcg tcaacagatc
    16381 cagcaagact aagtgaggca gcaaatgttc caatagctaa aacagttttt ggattaaata
    16441 atttcatttt ttcaactcct aaatttaatt aaaaatgttt acatgattat tatatatcgg
    16501 ctaaccgata tagtcaataa aaaataagaa aagccttata taattttggc ttttcttatt
    16561 ttatttgtta gttgaagtat taatatcaac gatttcttca gccaatttat ttaatttcat
    16621 agcatttatg aatctcatgt tgtctatact agagcgtttg ttggcaaggt cacttactgt
    16681 agttaagggt acgccagatt ctatggatat agaacgaact gatttaccac tatcaaacag
    16741 caaccattcg attttctttt tatcagcgta catttcaatg ctccttcttg ttttttcttt
    16801 attatagctc ttttttgtaa taaatcacaa tatcaagaga aaaattttct atagaaaggt
    16861 ggatttttat gagtattcgt tctccgtgta tccaaatgag gtttgttgct actttcgtta
    16921 tttgatatac taaaaataaa caacgaaaga aggaataaaa tgaagaaaaa gcaactatgg
    16981 tttgtctcta tgtttgcaat attttttatt attttaagtg gatgttcaag taataagaaa
    17041 tcggaagcta aagaagataa tagtttattg caaccaggaa ctgtttggaa agaagaagta
    17101 ggtggtctta ttcataattt aaaaattata gatgatacta cctgggaata ttctgaaagt
    17161 gtatggcatc cagatcctgt acaaataaca gttaagaggc aaaaagacta tgaaggttta
    17221 gaaagataca aaatagtaga ttctgcaggt attagggaat ttataaacaa acctgattca
    17281 ttatttattg ttgttcccta tgagaaggat ggcgtaaaaa aaataatttt tcttggatct
    17341 agcaaggatg agaagcgaac gaaagagaaa ttaattcatg atggatcaga gttaaataaa
    17401 tacaaattac aaaagactag tgagtgattg ctagtctttt tatttatcct gaaggaggaa
    17461 tcacagtggc aaaagttaaa acaccattcg aaaaagccgc gtctaaaatc ttagaacgcc
    17521 gtggtgtttc tgaaatacag tggaaaaaag aagttcttga aaaagcacaa tttgacctat
    17581 tacgaggaaa agataaggac ttagaagaat atatctatca acgtgaacgt gaaaaacttg
    17641 tattcgatga aattattaaa cattaaaagg agcgaataat cttatgtttg aatcaattac
    17701 aatgaatttt ttaactcaac cgaaagtagt agctgcagtt gatattttta gagcattaca
    17761 aactgccgca actagtttga aaaataatct gatgattttt gctgctgttg cggcagtggc
    17821 ttccattgct cttggaggta ttttcttctt ctttgggcga agaggagctg aaaacgggaa
    17881 gacacacgta ggttatgtat tgttgggggt aggagttatt ttagctgccg cttctattgt
    17941 agtttcaatg ttctcaatgt ttggacaaac cccacaagga ctataaaaaa acaagtagaa
    18001 ggagtaaaaa gtacgtggct actttttact ccttttttta tggaaggaga atattcatgt
    18061 tttttacgat ttcaggcaat gcaaaattgg ataaagagtt aataagaaaa gcaacgaaga
    18121 aagtgggaaa gcgtacttcc tttttaccga aaacaattaa atattctgtc attgaaacgg
    18181 aagaacagct acatgtgtta ggacaagtgt tagaacaaga gaatcaatct tctgttaaat
    18241 tgactctcac gttacatgat aaagaaggaa aaatagaaaa ggctggcaca gaatacgttt
    18301 ttggctcact ggattatcaa atttcagaag gtttttatcc tacattgatt gatttaatcc
    18361 gcctagatat atttaaagat acggatgaaa ccatgagtgt ggaagagtct tatcgaaacg
    18421 aaaaaatttt acaagtttta gaagaagagt tagaaagcga ccaaagaaaa gtgaatcaag
    18481 tgagtgaagt cgaagcaaac gaagaagtac catgggaacg cccaatcttt ccaaaggatg
    18541 aatcaaaaga aaaagagaaa ggaattattg acgaacaagc tgacattttg actcataaat
    18601 caatatttga ggaagagaac gaggtaatgg gtcaattgga ggtagatccc tttgaagaaa
    18661 caatggagga tgaagagacg gccgaagtag aagttgatcc agttgaagct aatgaagacc
    18721 caacatggac tgaaggggat tctcaggaat atattgaacc acttatcagt gaagaagtag
    18781 agaaaaatga aacagagata caaaaggcaa cggtatttga ttatattttg gatcaatatc
    18841 cgccagagca tgaatggatg aaagaaaaaa ataaattatt tttaaatgaa ctttattcga
    18901 aatatcaatt acctcaaacc tatcaagcat ttttagagag taaagaagaa ttaatctcac
    18961 agggtaaagg cacactttta gaacagttag agtctgtcca atcaacaaat tggcatgagc
    19021 ttgcacaaga agatttatta gctacttttg aagaacgtca acaagaaaca gatcaagaaa
    19081 ttaatgagta tgcgacggaa cagtcgtcga attgggagaa agcaaaagag gaactaaata
    19141 aagaagaaca gcgagtgatt gaagaagaag tacaaaaaat taaagagcgg tacgaaaaga
    19201 aacgtgacaa tgcgtattcc ttgtgtgtag aaaagatcaa caattttact cagacgaatc
    19261 aagaagcatt atcgaaagaa aaagaaaact tattaaaaga acgtataaaa gaacgaaaag
    19321 aagaatttta ccgagggttg cgtactgata agctaaggat tagcaaagaa ttaaatgaac
    19381 aactgaataa actctatcaa actacgactg aagttctgat ggaaaaacac gagcagatcc
    19441 aacaagaatt acaagcacaa attccaaaat ggaaaaaaga gtatgaaatt caccaacaag
    19501 aattgaaaga acaagaagaa aaacaacgga aaaaagaaaa agagcgcgaa caattagaac
    19561 taaaaaaacg tgaacaggat cttgcggaac aaaaaatggc gatagaaaaa caacggctag
    19621 agcaagaaaa ggaaaaagaa gcagctgctc gtaaggaacg tcaagaacaa atggatacat
    19681 tgcgacaagc acagttaaat tatctgacac atcctcaacc agtagctgct gttcaaacgc
    19741 cagtgaacaa ccaagcaaat ttaactcctt caccccagcg ttcctttaac ggatggatgg
    19801 tgggatgtat tgcaagttta agcttgcttc taggtggagg aacagtattt gcttttaatc
    19861 atatcaatca atcttcacag gctgattctg tagccacaac ggcgtcaatc aaggaagaag
    19921 cccaggaaca agcaagaaaa gagtatgaac aacaattaga agaattattg aatcgtacca
    19981 atcagtcaac aacagagtca agcatggaaa atagcaaaga gagtgattct agtaaggcta
    20041 aagaaggatc aagcgattca actgtacaat caaacacttc cgaaagttca gaatcaaatg
    20101 aggtgaaata atgcgtgtta gagaaacaac gaagcgaaaa gacaaacgat tcaatttaga
    20161 aaagaatagg tatctttctc atttctatcg ctatactccc tcaggagaag agctaccaga
    20221 aaaacatgac aaacgcattt cgaaaaagat tttttatagt ggacttgtat acctcccttt
    20281 agagtattta gtaacaagag taccagaagt tttcaaccga ttggaaattg ttaagggaag
    20341 cttacaagga ataaatctgt ttcaattaca ggaaatgcca caggtctttc attttgattc
    20401 agctggtttt tggaatccat ttactcctac aactagtttg ggtacacgtt tagcaatttc
    20461 gacagtttgt gtggttccag ctgtacttat gggattgaaa atggacatgt ggtttcgtcc
    20521 tctagcagat ggacaaaaag gggataatcg attaatgacc ttaaaagaaa tccaacagat
    20581 ttatccgcaa atacctgaaa caaaaactac ttttccaggt tatggaggta ttccaatcac
    20641 acattacaaa aaatattggt acattcaaac agatactgtt aatacgtgta ttgttggtac
    20701 ctctcgatca gggaaaggtc agattgaagt gttagccacc attgacaatt tatctcgtgc
    20761 agaaaaacaa agttcaatgg tcgttaatga tccaaaaaca gaattatatg ttggtagtaa
    20821 agatgaacta gaagctagag ggtatgatgt atatgccttt aatatcaccg atccactgca
    20881 atcaatgagt gataatccat tggcactcat cgtgaaatac tggaaacgag gagacataga
    20941 tactgcaaca cagttaacca atactttcac aaatacgatt tattatgatg ccaacgcttc
    21001 agataacaaa tactttaacg aaaacgcgca gaaagctgtc aatgcgctta tttttgcgtt
    21061 gttagaacaa gctgatcaaa caggagatta ctccaaattg acaccgaata atctcgttga
    21121 gcttctttct gagattggcg gttttaatta ttatccagat ccagacaatg aattcaaaca
    21181 gttgaatgcc ttagatgaat ttatgaatca gttgccacct ggaaacattg caaaaaaaca
    21241 atatggggca acgaaaattg gatctgataa agcgaaggga aatattttat caacggcaat
    21301 cacgggattg aatccattta ctctaacgaa aattgcaaag atgacttctc aatcaacgat
    21361 tgattataaa tcggttgggt ttccaaaata cttagatttg aaattacatg aaagtctttt
    21421 aaatcaacga gtcgtagtag aattttatca taagggaaag aaatttcatg aagaacgtgt
    21481 caaagtaggc tataaaggat tttgtgaaat caattttgat tgtcatttag ttgcaggtga
    21541 tcaagtttgt ttaaaatacg atcatcaagg aaaagaatat gtggcttggt atgaattttc
    21601 tcaaagagta ttgaaagacg aagagggtaa tatcgtttat cggaaaaaac gaggagaaac
    21661 ccatttgcca gaattagaaa aagaagccgt tctaacatta gatgaggaga aaagtaactt
    21721 attagtagag tctattcgga tgcactatac cgataaacca atggctattt ttatgcttac
    21781 acctgattat gatccatcta accatatcat tgttagtatt tttcttagtc agttatataa
    21841 agaattatct acgcaatgtg ttaagactaa aggagataaa tgtcaccgca ggattcattt
    21901 tattttagat gaatttggga atagtgtgac ctgtttagcc taaggataaa agaggctagt
    21961 tccaacgaac attggaataa ctttactatc gagaaatcaa atgacggggt aacgccctga
    22021 agggtttcca ctgatactgc gacatgcgtt agtaggatgt gcatccaaac gcgtatgaag
    22081 ctcgctgaag tcggcagaag ggtaccgtaa ggaaagacac gatacgtatc taccacgcaa
    22141 gtgctctaga ggtagggtat gtacctgata tgtcgggtgt cctaaaaagt tcaataaggt
    22201 gagaatgatt tgattatctg acaaacttgc gaatggaatg tctgaaacga ataactcata
    22261 gaaatgtgag ggggaagggg gatacgtcct ctttccattg actcgaggtt gagtaaaaat
    22321 gtgtttctat gaaaaacctt gcatggttaa aggctatgga gtagtcaaca ggcaaaagca
    22381 agcacctaag ttgaaatcta tggatagata gtaaggaaca ggggaagcat ctagcacgga
    22441 gggagcatac cgaagatgtg tttctaagga aaaaccgaaa tcggttataa cttaggtgaa
    22501 tagatgtgaa agtagagcca cgaccagtga aaatttcgta atgaaattgg aggaacaggc
    22561 tcaagtcgtt atttataata taagaaacct atttaaaatc atggattctc gtaagactaa
    22621 aaaggtcacg aaccagaatg gagcgtgata aaaccatgac taacacaaaa ggaattagct
    22681 taaagaacaa acaactcaga cacgccgaat actacgacat gactgagact ttcgatgaat
    22741 tgcacgcaat gagtgttgca aaatcaaatt ttaaaaatct catgaaattc attattgatg
    22801 acaataatat ctttctagcg tatagaaata tcaaaaagaa taaaggaagt gcaacggccg
    22861 gatacgatgg tgtcactata aaagacattg aaaaattggc atgtggtgac tttttaacta
    22921 ttattaaaag gcgatttaag gattacagac caagaaaagt taaaagagta gagatcccga
    22981 aaccaaacgg aaaacttcga cctttaggaa ttccttcaat atgggacagg atagtccagc
    23041 aatgtattct acaaatttta gaaccaatat gcgaagcaaa atttaataag catagctatg
    23101 gattcagacc aaattgttct acagaaaacg ccatagcaga ttgtcttgct agaatcaatc
    23161 aaagtaagat gaattatgtt gtagatattg atataaaagg attctttgac gaagtaaacc
    23221 ataccaaact tatgcgtcaa atatggacaa tggggattcg agataaacaa ctccttgtaa
    23281 ttattcgtaa gatgttaaag gctccgattg ttatgcgaaa tggcaatgtt gtttttccaa
    23341 ccaagggtac tccacaagga gggattttaa gtacactgct tgcgaatata tgcctgaatg
    23401 aatttgattg gtggatagct aatcaatggg aggaacgaac tgtcaaagag ctgaaacacc
    23461 actatcgaaa aaacggagca tgggataaag gaaatatcta ttcgaaatta agaagccaca
    23521 caagtttaaa agagatgtat ctggtacgct atgcagatga ttttaaaatt ttctgccgaa
    23581 caggagaaga agcccaaagg gctttttatg ccacacaaaa atggctcaga gaaagattaa
    23641 agctcccaat ttcaatggag aaatctaaag ttacgaacct aaataaagct gaaagtgaat
    23701 tcttgggttt ttcaataaga ctccacaaaa agggaaaaaa gaaagtggct ttcacgtacg
    23761 tttgtcgcaa agcagaagaa aacattaaaa ataaactaaa acaacagatt aaaaaaattc
    23821 aatacgctgg agcaaaaaaa aataggcacc gagcaatagg tgactacaac atgatggtca
    23881 tcggtatcca caattactat cggatagctt cacattgtag tgtcaatttc actgagattt
    23941 atagaagtgt taggacagta atagaagcaa gactgaaagc tagaggaatg acgaaaaatg
    24001 gaatctatgg acaagatcat gaaggatacc gtccgtatct aaagtctaag caaatgagat
    24061 atattgaagg ttttccgata cttccaattg gctatattaa aaaaagaact ccactcaaca
    24121 agcggagaaa tctaaataaa tataccaagg aagggagaaa gctcattcat caagagcaac
    24181 aagctataga aagctggaaa atcaagtatc ttgtaaaagg ttttagtaac aataagaaat
    24241 acacggtgga attttctgat aacaaaatat ctaagtttat ttcccaaaaa gggaaatgcg
    24301 ctatcacagg aaacgaactt ttgatggaag aaattgaatg ccatcacatt aacccatatc
    24361 atttgtccaa agacgatagt tacaagaacc ttgtcattat ctctagagaa atccatagat
    24421 taatccatgc aactagtgaa gaaactattc tgaaactgct tcggttactg aaactaaatc
    24481 actatcaaat tagaaaacta aacacgtatc gaaaaaaagc agctaatttt ccaatatcaa
    24541 tcaaaatgaa ttagatagga aacaaattat attgtaatta acgatggaac gccgtgtgcg
    24601 gtgaaagtcg cacgcacggt gtggaccggg ggaaaagacg gagataatat caaactctta
    24661 cctatcggaa ttgccaccaa tggataatat ggaaggaatc atgacggtca cagctggtag
    24721 aaacatgttg tgggatctgt ttattcaatc ttatcagcaa ctttatgcga agtatggaga
    24781 acaaaacgca gcgattatca aagaaaattg tcagacacat atttatatta tgtcgacaga
    24841 tgataatacc atcgaagaat tttctaaaaa agtggggaat aagacggttg aacaagagaa
    24901 cagtaccatc aattcattag gtatgaatac tcatatcaat cgcaatgttg attcagatcg
    24961 tatcttaact cctgaaagaa tttctacttt tttagaaggt gaaacgattg tactcgctcc
    25021 tttaaaacga caagatttga aaggtcataa aatacggccg tatcctattt ttaatcatgg
    25081 ggaaacgaat cttccttatg cttatcaata tattgaagat ttcaatccat cgtgggatat
    25141 caatgatata gacatacatt gtacacatgc ggacttggat cttaaggctt tacaaattga
    25201 ttatgattat ttcctaccag atgaatatgc tagaaatctc tatcatggac tgcatgatca
    25261 attagaagaa aaaaacgaag aaaatatgtt ttataaaatc gttcaatctc ttgagaatga
    25321 gacggctaaa aaattgttaa ttcaatttta cgaagaacaa gcagcagatc gacttcaaga
    25381 atatgttgaa aagttgatca aaaataaaga aatttctgaa atgattggga aacggttgtt
    25441 attggaatct gaaaaggtgg tgaaagaatg atcattggag gaattttttc tggcatagcc
    25501 gactggtggt caggcttatt cggagaaggg gatgcaaacc ccaaaaccgt aacgaaagtc
    25561 ttacaagatt atggtaatta tctgcagtat caagatgtat ttagttggat ttggaacact
    25621 tttctgtggg gattgattaa aggattatat aatctcaata ctttactaga aaaaaccatt
    25681 tatcaaagct ttgatttaaa agacttattg aacgccgctg gggtaaatgc actatttcaa
    25741 agtttgatta gtaaggtatt ggctcttttt tgtgtcgtca cattaattta tttaggcttg
    25801 aaatttttta tgagtaaaca cccaccaaaa gtcaaaaata tcttggttaa tttatttatg
    25861 gccatgatct tgatttttgg tgggagttct ttaatcgatg aagggttaaa tatcagtaaa
    25921 agcttttacg gagacgtcac tgcagcaaat aaagcagata aaacgggttc acctgctttt
    25981 caaattattc aaaataatgt gatcgatgtc agtacattac tagcaactga cccgaataaa
    26041 gtagaatccc tgccaacaga caaaagaaat gctttaacag cgaaaaattt taaaacagcg
    26101 aatatcaatg ggattattac tcctaaacaa gctaaagaaa tggcggataa agataagagt
    26161 ggtttatcag atttacaaaa ggatcggtta agagcgttac aataccgatt ggaactagat
    26221 gataatggga aagaaattcc tgttcaaatt agtgacgaag gcttagcaaa atatgtctat
    26281 acttcagggt atcgtcgata cagtagtaaa ccaggtatta tcttagctgg tgaatcttct
    26341 ttggcggtgg cctatttatt tatcctattt acgatcgtta cttgcattat tgagctggta
    26401 tttaaaaaat tctatttagt gattgccgcg tcaacggact ttgagacagg ccaacggatg
    26461 aaaagtgcga tagaagatat ttctcaatcc ttcttgttat tggcgtttac gattttagaa
    26521 ttacgaatct atacattaat gctttcaggt atcggtgatt tgcatgcggc aggaaagatc
    26581 aatggattct tgtatgttgt tgctttaatt gtgctaacta ttgcgctatt caaaggctct
    26641 caatcggtta cgaagatttt cggtgttgat acgagtctga aaaacggcag taattctctt
    26701 cttagcatgt ttgccttagg aaatattgcg aaaaatgtgg gtagcggagc taaaaacctt
    26761 gcaagtgctg gtaagagtgg tttaagccat ttaaatgata ttcgtaaaaa tggatttggc
    26821 catcgaaaag atgttacccc tgataacggg gaagaacaat cagacgataa agctacaact
    26881 gtacctaata gtaagaaaac agtttccgaa atgttcggga aagcgaaaaa tggtgtttct
    26941 aaagccgcag aaggtcttgg ttacgtcaat gaacgtgggt taaaaggaac agctgaagat
    27001 cttacagaaa aagccaaaga caccttagaa gagaaattag acggcacgag agctaaagaa
    27061 ttggctgaag ctgtgaagaa tccatccgaa gcactagaaa aacaaaaaga aaaagcttca
    27121 gaagtcaaag aaggactaaa agatgcgtat ggtgaaggac aagttaatgc agcagtaaaa
    27181 gctaatacaa caaccgaaaa agaaaatcaa gaaggtatag tgattccttc agtcaaagat
    27241 caccaagaag cgttgcactc taatgaaaat tcgattgaag agaaaaattc catagaagaa
    27301 agaaattcag aagaaggaaa aaatggacag ttaccaaaaa ctgatccaga acaatatcgc
    27361 tataaaccta acagtgacct tgaaaatgag aagcgaattt cagatttatc aaaagtaaat
    27421 caagaagaca aagcagaaaa tgagggacag ttaccaaaaa ctgatccaga acaatatcgg
    27481 tatagatctg ttaactccga aaatgaaaaa cgcatttcag atttaccaaa acgaaatcaa
    27541 gaagtacaaa cggatgagga ttccatcgtt ctgccaaatg ataatggaat cgaagttgga
    27601 actgaaaaat caacgaaaat tggtttacct aaggcacaaa atttaccaat gaaagatagt
    27661 cgtttgaatc aattcaagga taatgatcaa agttttgttc atcaatcacc tgcaggtact
    27721 gttcaaatga aaccaagtcg tttgcctgaa aatggaaatc tgacaactgt ttcttacaat
    27781 ttatctgaaa gtggtgagac agggaatgcg tccgttcaaa atgttgtgac aagagaagct
    27841 gcaccaaaac ctattcaaaa cgttcataca ggttacaagc cagcaaatgt ggcatttact
    27901 gcaccaacaa aaataaatgt gacaagagaa acaaaaaaca ggaacaatgc attgaaagaa
    27961 caactattga gggatatcaa acaggatatc aaaccataaa aggcctacaa gttaggcctt
    28021 ttttctatgt atgaaaagga gaaatcattt atggataaat atagtaacat gaaaaaccct
    28081 ccaagattta gtggagaatg gaagtttttc gcttttttct ttttagatct attaacgctt
    28141 ggtggctgct ttttttgggc gaaaatggtc aataatcttg tccacttacc actctttttt
    28201 gcactcttga attatggctt atggattgcg atagcgttag tgattgtttg gcgaccctat
    28261 aataacccag gtcaacgaca aatttttgcg attatcgagt ctattttttt tgcggacaag
    28321 aaccattatc atgcgttaga tcctaaccga aattatcatg gtacgtataa ggaggatgaa
    28381 taaatgcgag tcaaaggaca aaattcagtt gaaaggaaat ccattttgca gtttggaaaa
    28441 ccagaagagc gctctatctt ggacttattt ccgtataaat cctgtacaga agagggagtc
    28501 ttaattacta gagaagatca ttttcaacgt tattatcgtg tagtttctac agacgtggaa
    28561 ggattaaatg aacaagagaa actagaacga atgaatcagt tgaccaccgt catgcgtacg
    28621 tatgtgccaa caattaagtt agttagtttg accacagaga cggatctaac ggaacaaatc
    28681 gtgcaaaagc ggcaattatt agataaaaat cgtatggaac agtccttagg aagaaatcta
    28741 caacgattaa aaaaatatga aaagaaatta gtcgaagaaa tccaggaatt gaaacgagca
    28801 gaacaagaac gtcctgactt aagcttcttt ttcgtcattg aaggaaagac aatcaaggat
    28861 ttacaaacca gaaaccgtca gttaatgcga tctagtggca ttttagggtt aaaaccactc
    28921 tacaaaaaag aattgatcaa gattctgtat cgaatgaaca atatgaatga tgagtaggaa
    28981 tggagaagag agaatgaaat atccgttgat atggttagaa aaagatgttc cgaaggaaga
    29041 gaccactaga aaatttcctc acactttaag cctgggtaag ttgggaaaag ggcaatcttt
    29101 taaccaagta aagaatcaaa caagaagagg tgactgtaca tgttagaagc aattaaaaca
    29161 gctttttcac cacaaaatga tcaaaaagta cttgatccat taaagcaact aggaaatcgg
    29221 gaaatcgaaa ttttaaaatc caaagggtat gatttagatt ttttaaaaca agtgatgcca
    29281 caaggtgggt taaattttga tgaagaatat gtgacgtatg gtaatggtta ttcacgatgt
    29341 gtgacagttt atcactacac aaaaaatcct acgctttttt ggttggccaa tctcatgaac
    29401 aatcctcata cagtggccac actcgatgtt agcacagatg aaaagcaaaa agtgattgat
    29461 caaatcaatc gtgccttaga tgaattaaat gatcgatcag ataatgaacg aaaagcgact
    29521 gaccgaaata aaagcgcgga agaatacctg gaactagcgg aatatgctag aaaattgact
    29581 tctaatgggg aaatttctaa gcaagtcaaa gtgagagtac atgtttacgg aaacacgatt
    29641 caagaagtag atgaacgagc gcaggaactg atcgaaaatc tcaaagggat ggattatcgt
    29701 gcggtgactt atctgcataa aaccaaacga gattggcaat cgatgtttac catgttcgat
    29761 gaacaagctg aatggttcgg aaatatcaaa gggcaatcac taccatcgtt aaacattggc
    29821 ggaggtttcc cgttccacca ccaaacgcta aaagatccag gagggacaca atatggggaa
    29881 accatgacag gcggcccatt tgtctggaat gcgacgtata aaaatagtgt acggttgtct
    29941 actaatacct tgcttctagg aatgatggga gctggtaaat cgaccgttct taaaatgatc
    30001 gcggaagccc atttagctgc aggagacttt atttggggct ttgaaaaggg aaaagacttt
    30061 attcctttct taaaggaata taacggtatt atggtgcgtt tagacggatc tgacggaatg
    30121 atcaatcctt tagagatatt tgccacacgg acgtatgatg aagcatccag tttatatgac
    30181 gatggatcag tcaaagattt gaagatcaat gaagcagcgt cctatcaaac acacttagac
    30241 aaagtggtct atcaggtaca gttagtgagt cctcagctaa aaggaacgat gaaagcagaa
    30301 tttaagacct acttaaatcg tttttatgaa gagtatggaa cagtaccacg cggctttact
    30361 tcctcaaatt cgcgttcaaa tactgatacg caagtcacag ggaaagatcc agaagcttat
    30421 ccgacgttca aagaattttt agacttttta ggacaactgg aattaccagg tgcttcccaa
    30481 gagaaaaaga atcgaaaaga agaaatggaa tccatcgtag aatccttatg tgagacgtat
    30541 ggcatgattt ttgatggtca cagtacgatt cgacaccttg accaacaaca gttggtcttt
    30601 tttgacattg actctattac aggcttagat cgaggggtac aacaatgtca aatgtacatg
    30661 gctatgacgt tgatttggaa tcaggcattg attcaaggaa gaagacaacg acgtttactt
    30721 aaagaaaaac aaatggaaga acaagacttc aaacgcttct tggcgatgat tgatgagtgc
    30781 cataatggtg cgacctgttc tgcagtgaaa agctgtgggt tgcaagtagt ctaaaaacta
    30841 ttgtaataac tcttataacg agaagtcaaa tgagtgggta acgccacaaa gggcttccac
    30901 tgatactccg acatgcaaca agtagtttat gcagaccaac gttgtgtgaa gctcggtgaa
    30961 gtcggctgaa ggataccgta aggtaaaaga aatagtgaat accacgaaag ttctttagag
    31021 gtaaagggtg tatccgataa gtcgggtgtc caaaaaaact taatatggtg agtatgtaca
    31081 aacgtactga cgaactagcg aatgtactgt ccgaaaggca tagctcctag aaatgggaga
    31141 gacagtgagc aaaaaatcac tcattgtgct aacttgtggt tgagtaaaag tcgttgttat
    31201 gaaagaccat gctgcgttac aggcgtagga gaagttaggg ggcaaaagct agcatctaag
    31261 ttaaggcatg tggatagata taagggaaca ggggaagcca tcaacatgga gagtgcatac
    31321 tcgatgaagt ggtagtaaga aatatgtgaa tgacaaataa cttactttag tgatggtgaa
    31381 agtagagtca cgactgatga aggttctgta atggaactgg aggaacaggc tcgattcgtc
    31441 tgtaaaagtc atgaaacccg ttcaaccatg ggattctcgt atgactaaaa aggtcacgag
    31501 ccaattggag cgtgataaac catgacaaaa gaaacaagtc caaaagatag gaagttgcgg
    31561 catgcagaat attatggcat gacggaaatc ttcgataaga tatactccaa aagtttgaag
    31621 ggagataatt tcaagaatct aatgcagatt atcatttctg ataacaacat tgtcctagca
    31681 tatcgtaata tcaagagaaa tcacggtagt gtgacaagag gagaagatgg agtaacgatt
    31741 aaagatattg aaaatctcaa ccgtaatgaa ttcgtagaaa ttgttaggaa gcgattcgca
    31801 cattataacc ctcggaaagt aaggcgtgta gaaattccta aatataatgg taaattaaga
    31861 ccgttgggta ttccatcaat atgggataga atcgcgcagc aatgcatctt acaagtatta
    31921 gaaccaatat gtgaagcaaa attcaataat cacagctatg gtttccgccc aaatagatca
    31981 gcagaacacg caatagcaga ttgtatggcc cgaatgaatc aaagtcacat ggaatatgtg
    32041 gtagatgtag atatcaaagg tttcttcgac gaagtcaatc atactaaact catgagacaa
    32101 atctggtcta tgggtatacg agacaaacag cttctcttaa tcattaggaa aatgttaaga
    32161 gcacccgtag tacttccaaa tgggaagttg atatacccaa caaaaggaac accacaaggc
    32221 ggaatactta gcccattact tgcgaacatc aatctcaacg aatttgactg gtggatagca
    32281 aatcagtggg aggaaaaaga tgccaaagag ctaaaacatc attttaggaa aaatggagct
    32341 tgggataaag gtaatatcta tcacaagctc agaaagagta caactctaaa agaaatatac
    32401 ctagtgagat acgcagatga ttttaaaatt ttctgtagaa attataatga agcgaaaaaa
    32461 gttttctatg caactaaaat gtggttacag gagcgtctaa agttaccaat atctgaagaa
    32521 aagtcaaaaa tcacaaatct ttcaaaagaa gaaagtgaat ttttaggctt tacgatgaaa
    32581 ttagtgacca aaggtaacaa aaaggttgtt aatacgcata taggtacaaa agcacaaagc
    32641 atgattaaag tgaaactaaa aaaacaaatc aaacgaattc aaaaaagtcc taatagcaaa
    32701 gataccttta tctatattgg agtctataac agtatggtta ttgggattca taattacttc
    32761 aaaattgcga ctcattgtag tgtagcaatg cgaaaaattg caagagaact cagaccaagt
    32821 tttgaaatac gactacgaga acaaggaatc tcaaaagaag gacaatacgg aaagtacgaa
    32881 ggatacaagc cttacctacg gtcaggacaa atacgatata taagagggtt tccaatatta
    32941 ccagtagggt atattcaaca cagacatccg atgtgtaaaa aaagaaatat taataaatac
    33001 accgaagaag gtagggaagc cattcataag aagcaacaaa ccgtagaaga atggaagata
    33061 tcgtggttgt gtagcaatcc agtgcttagt aagagagcaa cgattgaatt tgcggacaat
    33121 cgaatttcaa aattcatcgc tcaaaaggga agatgtgcag taacaggtga ggagcttatc
    33181 ttatctgaaa tgcattgtca tcatattatc ccttatcatg aaagcaaaag tgatagctat
    33241 gaaaacctag tgattgttac tgaggaggtt catcgggtaa tacacgctac acaaagtgaa
    33301 acgattgagg aacttctaaa atatctaaaa ttaaatccaa aacaaaaaga aaaactcaat
    33361 gagttgagat taaaagttgg taacgaagaa atatcttaat aaatatttgt aggacgggaa
    33421 aacagaatgt cttttataga cgagggaacg ccgtatgcgg tgaaagtcgc acgtacggtg
    33481 tggactgggg gaaaagacgg agataatatc aaactcttac ctatcagtat cgattaatcc
    33541 agattttatt gaaacggtaa attatgtcac aaactttcaa cgagaaatgc gtaaagtaga
    33601 agcaatgact gttttagcta cacaatcccc acaagaaatg gtgccagaaa atatgtcttc
    33661 tgataacttc tcgaaactga agaaagtctt tgaattttct tctacgaaga tctttatgcg
    33721 tatggatgaa tctattttac gtcatataga aggattagtt ggtaaatcaa tgacgaactc
    33781 agaactagaa tccattcctc aacaaaatca aggagacgct gtgatcaatt ttggctcaaa
    33841 agaaaccatt cgtgttcatt ttagtccgaa caaacgtcaa ttgaaattgt ttgatggtgg
    33901 aaagtaactt cttgtatttt ggtgtataca agtatatact aatgtgtgag agaaggaggg
    33961 attccatgtt agtaaaagaa atcgaaatga aaaaatgggg aaattcacaa ggtattcgtt
    34021 ttggaaaaga agaattgtca gttctaggag aaactaatac tgaaaattta aaattcgaaa
    34081 tggtggtaac agaaggaaaa attgttttaa ctcctaaaaa taaaaagcca gaaactttag
    34141 atgaattgtt cgccaattat gaaggagaac ccttaggaaa agaagacaaa tatgaatggg
    34201 gaaatatgca aggtagggag atcatttaat gaaaaagaac tatcatgatt tatcgcaagg
    34261 agatcttgtt tatattgatt taaatcctac caaaggacat gaacaacggg gaaaacgacc
    34321 atgtattatt ttatctaaac ctaataaata tttgaactat atgattggtg tcgcaccgat
    34381 aacaacaaaa gcgaagcctt ttcctgtaca tgttgatttg aatggtacgc aaaaaataaa
    34441 aggacaaatt cttttggaac accatcgaat gattgacatt gagagtagag gttttcagtt
    34501 tgtggaagct gtgccaaagg aaattttaga agaatgtatt gaaaaaatta aattatttta
    34561 ttaaaagcag cgaagaataa ttattatttc ttcgcttttt tgttgtttaa aattaaaaag
    34621 ttaggagtac tgactatatg gaaaatgata caaatatagt tatggaacat ttgaagcgtc
    34681 gtgcaaagcg acgcttattt ttgtggttgt ttggtacttc tgcaggtttg attactattt
    34741 tgatcactgt gttcgtaacc ctttttctaa tacttgcggc gggttcgatt gataattcgg
    34801 attccgattc aagtagtggt ggcgaagctt ttacaggaga gtattcggaa ggcttaccga
    34861 tttataaaga aatcaaagga agaggccctt tttctgatga gattgcgcaa tatgccgtag
    34921 gtgcagcagt gaaatataaa ttattaccaa gtgtgattct ttcgcaatac ggttatgaat
    34981 cagcgtttgg tacgtcggcg tccgcaagaa atgatctcaa ctattttggg attacttggt
    35041 ttgatggttg tctgtttcct aaaggaactg cacgaggaat tggtggcatt gaagggggct
    35101 ggtacatgaa gtttcccaac tcaaaagctg cattctccta ttacggcttt atggtagcca
    35161 cacaatcaaa ttttaatgca tgtgtaggaa ataaaagccc tggcgcaagc ttattgatct
    35221 taggacgagg tggttatgcc gctgcaggaa ttactgaaga tagtccgtat tatacaggtt
    35281 gtatgtcaat tatcacttct aataaattaa ccgaatatga tgaattcgcc atcaaacatt
    35341 ggggtgaagg tggcaataac aatggcacaa ttactggtga atggacgaat ccattccctg
    35401 gcagcagttt agataaaagt tccttcagcg gtggtcaatt atttggaacg aatccaggcg
    35461 gtgaattccg tccgaacggc ttccatgatg gattagattt tggttcagtt gatcatccag
    35521 gaagtgagat tcatgcggtt catggcggaa aagtcgtgta cgttggcaat cctggtattt
    35581 caggtttggg cgcgtgtgtg atcgtgatta attacgatgg cttgaatatg gtgtatcaag
    35641 aatttgcaaa tagtacagga aattctcgag tgaaagtagg cgatcaagtg aaagttggtc
    35701 aagtaattgg gatacgagat acagcacact tgcatttagg atttactcga atggattggc
    35761 gtcaagcaca aggacatgca ttcattgatg atggtacatg gatcgatccg ttaccatttt
    35821 tgaatagcag taaaaaatag atcaggagaa aaaatatgga aaataaaacg ttaaaaatcg
    35881 tcttaacagc tgcaattagc gttagtttaa tcggcaatat tgcgttgttt tggcagctga
    35941 aagaggaaca agcagcaaat acctataaaa ttgaagaagt ggctaaaaac gcgtctgaga
    36001 agctcaaaaa aaattcctct gaggcacagg cgaagatcga caagttaaat caaaccatca
    36061 atgagaaaaa ccaagaaatc gatcagctga agcaacaaga tggcacaaaa gcaaaagagg
    36121 aagtaactga agcacaaaga aagacggcag aagagttcgg tcaattggcc attgataaat
    36181 cattaagcag aaatgaatta acggaaaaac taaaagatgt cgcaacccaa gaagtgatcg
    36241 acaaattaag tcctacagac gatgatcacc aacatgatga ttacggaagt tactccttta
    36301 cattaggtga cgtgcaaact tacgctcaaa caagcagtgt aaaagaggaa caaaattttg
    36361 tcgtatttgt tgattataca atcggcaatc cgcaattcaa agatgtcaaa ccacaaaaaa
    36421 taaaaggtgg attaactgtc actgaaaaac aagtagatgg tcaatggaaa gtcatagact
    36481 ttagttattt cactcgttag gaggaagaaa atgagtaaga aaaaaggaga aagacaacgt
    36541 ttcaaaaaac gaaaaagtta tcttcaatgg ctgggaatct ttatgattct cggctttttg
    36601 attcttgcta gtccgattta cacgcatcag aaggtagaca taccagatga agtaagcacg
    36661 aacgcctttt taaacacgaa ggaactaacg atggtttcaa aagaaaaagg agcgaaccag
    36721 caattagttt ttgaatttgc aatcgacgat gaagatcaaa gcttattaaa agaactggct
    36781 aatcttaatt atcgcgtaga agtaaagaca gctaaagggg attatcaagc aatacgagcc
    36841 aaagtgatca aggtgtctga tgattatttt gcagtgaagc taacgcatgt accagaagaa
    36901 tatatcgcca tgcgtttaac cattattcct gaaaaaattg atccaaaagt ggatatgcaa
    36961 gaaccacaag atctgattta ttacgtgcac gaagataagg ttaaagatca agtgaaagat
    37021 gaagattatg aacaacacgc gatcaattac aaagtgaaag gatacaagaa agaacaaaaa
    37081 gcagctcaaa aacaaatgga atctttccaa gcaaccattg atttgaatga agaattagtg
    37141 aagaagctaa aagatcaatt gccttatcaa gtcgcagatg atcaggaaaa tactgaaaac
    37201 aagattaata gctaccagca agaaattgaa acatcgaaaa cgcaaatgaa agatcaagaa
    37261 gagatcattc aaaaacttca agaaaaaatt gatcgtatga caaaagaaaa gatttagaag
    37321 gacaggtgga gtgaaaaaat gaagcgaaca aacttggctg acaaagatac tttcgctgag
    37381 cagaaagtat tgattaaagc ctatctcaaa gttgtaaaag ctaaagaaat atgtcgagaa
    37441 gtgaatttat ctaatacaac aatatctgag ttgaagaatg gtcgaaagaa tttagatact
    37501 ttaaaattca gatcatttga agctttgtat ttagctgcta aaaaatattt tacagctgat
    37561 aacaaataaa aaacaggagt attttatgtg aaaaaagtat ataaaaaatg cttatgaatc
    37621 agctatatca ccttaaccat ttgttaatga gatgggagaa aacattaacc acgattctaa
    37681 cgcaaacatc aagcacataa aacatttaac actcctcctt tctggctgaa gatttcaacc
    37741 aaacaggaag acagcgtatc aattatagca tacacttttt cttaaattca tttttcatat
    37801 gacaaaatat ttccttctaa tcgacaaagt tagaaggatt ttttattgtc taaatacaca
    37861 aataacctta atttataaag agcataagga aacgtgtacc cactttcaaa ataaagtggg
    37921 tagataggct gtgcctatca cgtttctgaa aaaaataaat gaccccaaaa ttttcaaatt
    37981 atgtgtaggt ttatgggtag caaaaatatg aatgtgggta gcacaaaagt tcatttgtgg
    38041 gtagtaaaat ttaaatatgt gtagcaatgt gtgtagctac acacattgct acacacgtta
    38101 taacatatag tcaaaaggag atatttatgg aagtaaaaat aagagatatt gatgaaaaaa
    38161 cgattcaaag aattgaccga agatgtattg aattaagtga acgtactggg actaaatgga
    38221 gccgaaatcg atacctaaaa gttttgatcg aaaatgattt tgatcacgct cttctggatt
    38281 ataaaaaaga tcaatttgat cggttgttag aaaaatttgt ggatattcaa acttataata
    38341 cgaaaatttt agaagaatat attgcaacaa ataatcaatt aatcgccttg ttaattgaac
    38401 agtaaaaata atattgtgaa tttataaaag gaggaaatca actttggcga aagcaacaag
    38461 aaaacatatt tatctttatg atatgcatat cgaagtactt gatgagataa tttctactca
    38521 tgacgatata tccaattata gtgaagcagt tagacatttg tgtatgatgt atgatcccaa
    38581 aactgaagaa aagataagtc ccagtcaaat caaactaaat gcaattggaa aagaagtttc
    38641 tattttaact gaaatggttt cggagtttgc agatcttcat ttaaaagata caggaatatt
    38701 aattggtaca aattcaactg tttatcaaga agcgaaagag cgtgtggaag gcaagataaa
    38761 agcaaatcaa acgaagaaat attctcctaa gataaagaaa acaataagcg aatcagtgac
    38821 tacaaaaagt gaagtatttg atccaacaag gtttttaaaa cgataaaaat tagaaggaga
    38881 acgtgatgag taaatcacct gcagtcattc tcacttgtca atttaccttg cccaataaaa
    38941 aatctttttc aacatacatt gattatatga caagagaaaa agcgctggaa gaaatggaac
    39001 ggcgcacgct cgaagaagaa caggaactgc aacgaatcaa gaatgcttta gaggattttt
    39061 atattcctga aggagaaact ttttcggaga gtaagacgga taaagaattc agtgaaacgt
    39121 cgaatgaagc gcaatcgttg atggaatatg gaatcaattt tgacaagtta gaggaacaag
    39181 attttaccaa atatctttct tatatgacgc gtcactatgc gttagaacaa aaaaaggaac
    39241 taacggaaag ggaaaaaata gaatatcaac gtttgaatca agcaatggaa aaatatcaag
    39301 cagaaccaca caaaaaaact tcaggaactc ttcctggagt tttttctata tcttcagacg
    39361 aagtaaaagg aagtgatctg aaggagatta agcagatctt ccaaagaggg caacaaaaag
    39421 gctcaatcat ttatcaagat gttgtttctc atgataattc gtatcttgaa aaaataggat
    39481 tgtacgatcc caaaacagat actttagatg aagttggact aaaagctgct ggaaggaaaa
    39541 tgatggagac gttgtttgag aaagaaaaac tgaatgatac gggatattgg atggctacca
    39601 ttcaccgtaa cactaagcat attcatattc attttgcagt tgttgaaaaa gaaaatacgc
    39661 gtaaaccata cactgaggtc gaaaatggtg tgagttatat cgtaccgaaa ggaaagagaa
    39721 gacaagcaac attagacgca atgaagacca attatgtgca tgaattagaa cgtttttctt
    39781 atgaaaagga tcgaatgata ggcatggaga aacgaaattt attaacgcgg aaaagtgatt
    39841 tgcgtaacag cttaacaaaa gtggtaaaag agccagtacg ttatgatcga cacgcaatga
    39901 acttattaaa tgaagtatat aaaaccttac ctgacaaacg ttcggaatgg aattatgggg
    39961 atgaaaatcg aactaaactt tcaccataca caagagagaa actcgacgag ttaacccaat
    40021 atgtgttaac aaaagaacct gaataccaag aatatataca gatttcaaaa gcattgaaag
    40081 aagaagcaaa aagtctttat ggggaaagca agagagaatc aaaggatgca gagaaaaatg
    40141 ctctctttga tttaaaaaag cgcacaggaa atgccatcct aacagagctg aagagacagg
    40201 atagtcaaat aaaaccatta atagaaagtg ttgatcagac gcaatctatt tacaatgaac
    40261 gatcctttcg aacgcttaaa caattgccaa cgaatgaata caaatatagt tacgaagaat
    40321 tcatgaagcg caggaaacaa ttccaacaaa gagttgtcac gcagcggagt ttgcgtcaat
    40381 taaatcgaac gattaatgcc catgaagaaa aataccacgc aagtaaagca tacgaagagc
    40441 aacaacgaag aatccaaatg gaacaagaaa gacagtaaag acagtaaaga cagtaggagg
    40501 aatagcaatg aaacaatatt tagatcaatg gaaagttata gaaggatcat taagagaaga
    40561 acgaatcgaa caacttcccg attgtttaga aaaagagcat ttgtttcaga taagagaaat
    40621 gttgataaac gaacagtttg atccaaatca atttttagtc gttgagtacc cagctactgg
    40681 tgtgtactgt tgtaatcatg tgaagggtga aaaatatttt atcattcaag aatatgaggg
    40741 caagttagcg ccttattata ctacttggga aatgaatgaa gaggggatca ataacttccc
    40801 gtgtaaaagc attgaagagt ctatttcact cacagaatgt tagttgttaa gtgaataaaa
    40861 gaagtaaaag agtcctgaac gtgattgtcc aggactcttt tttttcactg aattgttttc
    40921 cgccaattca ttgagtggtg cgatttccgt ctacattata tcaaaagaaa ggaggaagaa
    40981 gaaatggctt attcaacgat tggagttgtt gttgaaaaaa gcagagacaa tcttgttttt
    41041 gtgacagaaa ttcaaacagg cagagctttt gtagtcacag acaaagcggc aaaagcatat
    41101 caaagtggcg atattttaac gttaaatctg actacgaaga cgttcgtcga tgcggcagaa
    41161 gattatcc
//
LOCUS       DAIGTA010000022        36704 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.022, whole genome shotgun sequence.
ACCESSION   DAIGTA010000022 DAIGTA010000000
VERSION     DAIGTA010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.022"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            647..964
                     /locus_tag="NOB43_001199"
     CDS             647..964
                     /locus_tag="NOB43_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI0982070.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="NOB43_001200"
     CDS             complement(1055..1420)
                     /locus_tag="NOB43_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982071.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="NOB43_001201"
     CDS             1628..2110
                     /locus_tag="NOB43_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982072.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="NOB43_001202"
     CDS             2307..3197
                     /locus_tag="NOB43_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HCI0982073.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3484..4758)
                     /locus_tag="NOB43_001203"
     CDS             complement(3484..4758)
                     /locus_tag="NOB43_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0982074.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            5031..7502
                     /locus_tag="NOB43_001204"
     CDS             5031..7502
                     /locus_tag="NOB43_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0982075.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7605..9341)
                     /locus_tag="NOB43_001205"
     CDS             complement(7605..9341)
                     /locus_tag="NOB43_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HCI0982076.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9338..10042)
                     /locus_tag="NOB43_001206"
     CDS             complement(9338..10042)
                     /locus_tag="NOB43_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0982077.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            10173..10676
                     /locus_tag="NOB43_001207"
     CDS             10173..10676
                     /locus_tag="NOB43_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCI0982078.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10636..10974
                     /locus_tag="NOB43_001208"
     CDS             10636..10974
                     /locus_tag="NOB43_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HCI0982079.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10995..12413
                     /gene="ffh"
                     /locus_tag="NOB43_001209"
     CDS             10995..12413
                     /gene="ffh"
                     /locus_tag="NOB43_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCI0982080.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12525..13103
                     /locus_tag="NOB43_001210"
     CDS             12525..13103
                     /locus_tag="NOB43_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCI0982081.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            13055..13627
                     /locus_tag="NOB43_001211"
     CDS             13055..13627
                     /locus_tag="NOB43_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0982082.1"
                     /translation="MFPQRRGRTYRQKGRIKHAKIIFYGAISLDGYLATKTDDLQWLF
                     DTPTGKQTTYEAFYETIDTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPD
                     AEVVNEDPVAFLKNLQMTEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIP
                     LFQKGTYEARFEMLDTTRFGEFIELHYVRK"
     gene            complement(13706..14260)
                     /locus_tag="NOB43_001212"
     CDS             complement(13706..14260)
                     /locus_tag="NOB43_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI0982083.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14513..14788
                     /gene="rpsP"
                     /locus_tag="NOB43_001213"
     CDS             14513..14788
                     /gene="rpsP"
                     /locus_tag="NOB43_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCI0982084.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14800..15051
                     /locus_tag="NOB43_001214"
     CDS             14800..15051
                     /locus_tag="NOB43_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HCI0982085.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            15176..15967
                     /locus_tag="NOB43_001215"
     CDS             15176..15967
                     /locus_tag="NOB43_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982086.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            16137..16658
                     /gene="rimM"
                     /locus_tag="NOB43_001216"
     CDS             16137..16658
                     /gene="rimM"
                     /locus_tag="NOB43_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCI0982087.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16648..17409
                     /gene="trmD"
                     /locus_tag="NOB43_001217"
     CDS             16648..17409
                     /gene="trmD"
                     /locus_tag="NOB43_001217"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCI0982088.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17545..17892
                     /gene="rplS"
                     /locus_tag="NOB43_001218"
     CDS             17545..17892
                     /gene="rplS"
                     /locus_tag="NOB43_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCI0982089.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            18150..18443
                     /locus_tag="NOB43_001219"
     CDS             18150..18443
                     /locus_tag="NOB43_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HCI0982090.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            19286..21613
                     /locus_tag="NOB43_001220"
     CDS             19286..21613
                     /locus_tag="NOB43_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0982091.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            21739..22068
                     /locus_tag="NOB43_001221"
     CDS             21739..22068
                     /locus_tag="NOB43_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCI0982092.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            22108..23112
                     /locus_tag="NOB43_001222"
     CDS             22108..23112
                     /locus_tag="NOB43_001222"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0982093.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            23109..24538
                     /locus_tag="NOB43_001223"
                     /pseudo
     CDS             23109..24538
                     /locus_tag="NOB43_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            24744..25916
                     /locus_tag="NOB43_001224"
     CDS             24744..25916
                     /locus_tag="NOB43_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0982094.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(26078..26533)
                     /locus_tag="NOB43_001225"
     CDS             complement(26078..26533)
                     /locus_tag="NOB43_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982095.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            27123..27545
                     /locus_tag="NOB43_001226"
     CDS             27123..27545
                     /locus_tag="NOB43_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982096.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(27711..28904)
                     /locus_tag="NOB43_001227"
     CDS             complement(27711..28904)
                     /locus_tag="NOB43_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0982097.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            29128..29505
                     /locus_tag="NOB43_001228"
     CDS             29128..29505
                     /locus_tag="NOB43_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0982098.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            29493..29831
                     /locus_tag="NOB43_001229"
     CDS             29493..29831
                     /locus_tag="NOB43_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0982099.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            29965..30408
                     /locus_tag="NOB43_001230"
     CDS             29965..30408
                     /locus_tag="NOB43_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCI0982100.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            30670..31485
                     /locus_tag="NOB43_001231"
     CDS             30670..31485
                     /locus_tag="NOB43_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0982101.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            31495..32157
                     /locus_tag="NOB43_001232"
     CDS             31495..32157
                     /locus_tag="NOB43_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI0982102.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            32362..34026
                     /gene="alsS"
                     /locus_tag="NOB43_001233"
     CDS             32362..34026
                     /gene="alsS"
                     /locus_tag="NOB43_001233"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HCI0982103.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            34039..34749
                     /gene="budA"
                     /locus_tag="NOB43_001234"
     CDS             34039..34749
                     /gene="budA"
                     /locus_tag="NOB43_001234"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HCI0982104.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            34879..35376
                     /locus_tag="NOB43_001235"
     CDS             34879..35376
                     /locus_tag="NOB43_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HCI0982105.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            35561..35821
                     /locus_tag="NOB43_001236"
     CDS             35561..35821
                     /locus_tag="NOB43_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982106.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(36183..36422)
                     /locus_tag="NOB43_001237"
     CDS             complement(36183..36422)
                     /locus_tag="NOB43_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982107.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT        12338 a         6418 c         7305 g        10643 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     3421 tgaagacaaa tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt
     3481 tttttagttt tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa
     3541 gttgcgataa ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccctcagt
     3601 gacgccgttt gagtgggaca ccttaaaggc atttgaaata cccgattggt agcaatggaa
     3661 gatcgtgaat ttctttttaa acgactgagg taacgtagat gaaattgttt taagggtttc
     3721 ttgaaagcct tccgtacctc gtttaacgaa ataatagcgt aataattgac aaaaatgata
     3781 cgcagttcgc aattcttcgt tgtagcttaa cagctcatca acgatttctg tttgactaat
     3841 tggtcgttta aacagtcgat gataatgccg tttgagtggc tcccatgtcg tggaatcttt
     3901 gagtaagagt ttccaatatc gcttgagccg acggtacttc ttctgatttt cagagtgtga
     3961 ggttcgaaaa cgattcatga tctggacacg taattgattg aagctgcgat tgatgtgttg
     4021 gacaatatga aagcggtcag ttacgatctc cgcatttgga aagactgttt taagcaactg
     4081 acaatagctg gcattcatgt ccatcactag gtacttgacc tttaaacggg cctttctagg
     4141 aaagcgcagg aagtattgag ttagtttgta aagtctgcga tcttcaagga tcgtaaatag
     4201 ctgattggtt gtcccatcaa cacaaataaa actcatggaa ccagaaacag aattcattga
     4261 tttgaactca tccatacaca acaccgtcgg aaggaagttc atacgtggct ggtaatgctt
     4321 cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag acgaagtact tcttagcgat
     4381 tagtttacgt gattgatttt cgtacagttc catgagaatc gcctgcttca gttcctttgt
     4441 tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa aaggtccttc cacaatcatg
     4501 gcagagaaaa cgggtacgtt ttaattctaa aatagttaac ttttctttga ctttcaacat
     4561 ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga accgatcgac agtgttcaca
     4621 ataggaagaa gagtcatcca attttccttt aataaactgc gcttgaacgc ctttatattc
     4681 tttttcaatc agccattctt catcaaaaaa taaatgttta tctgttaatc cgagtaattt
     4741 tctagtatga ttatccattg agagactcct ttggtaggat gacgttttgg tcgactaaat
     4801 tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa aaagtgttag tagaaaatcg
     4861 ccttcgattt tccaccaaca caaaatatta tagaaccctt tttttttgct atatgacagg
     4921 aatgaaaggt gtttgcaagc ttaatgtgag gaacactttc catatctgtt ctatactgga
     4981 taggagaagt ttggaaatat ccagaaaacg aaatcaatcg aggtagccac atgaagaata
     5041 aatggataaa tcgaagtaaa aaaaagaaag taacacaaag atcatcagat aaagtcatcc
     5101 gtctttttcc atcgtataaa gaaggattaa cggcagatca agtcaaggaa cgaatagaaa
     5161 aaggtgcagc aaataattca gtcgatccca cattcaaaac aaatcagcaa atcgtattgg
     5221 aaaacatatt tacgtatttc aatttgatct ttcttatctt agccattttg ctttgtttag
     5281 tagaatccta taagaacttg acttttttac cagttatcat agccaataca ggaatcgcca
     5341 tttttcagga aattcgatcc aaaaagatct tggacgaact aaatgtttta aatacagcaa
     5401 aagtcaatgt catacgagac gggatagaac aaacaataga tatagaagac cttgtaatag
     5461 atgacattgt tattttagag actggatatc aaattccagc agatgcagag gtcgtggaag
     5521 ggaaactgca agttaatgag gctttattga caggcgaagc agatgaaata accaaagaaa
     5581 taggtgatcc attaatgtcc ggcagtttca ttgtttccgg aaaagcttac gcccgattag
     5641 acaaagttgg agcagattcg tatatttccc agctgacagt caaagccaag acaatgggag
     5701 aaggagaaca gtcggagatg attgcttctc ttaatcaatt gatcaaatgg attgggatca
     5761 tcattattcc tatcggtatc ctgctttttt ctcaaagtta cttttttaat ggaaacacga
     5821 tcaaagaaag tgtcgttgca atggaagcag cattgatcgg tatgatacct gaaggactgt
     5881 acttgctgac gacgattgca ttagcattaa gtgcgactaa actagcaaag caaagagttc
     5941 ttttacacaa tatgaaaagc attgagacat tggcaagggt aaatgtcctt tgtgtagata
     6001 aaacaggaac gatcacagaa aataaaatgt ctgttcaaaa aatgatcgtc tctaaaaaac
     6061 aagaaataat cagtcagtca gatcaattgg aagcatgcat tgctgactat gcaaaagcga
     6121 tggcaggaga caatgcaaca atggaagctg ttaaagcata ttttacaaaa accactgatc
     6181 aatcctatca ccatgttatt cctttttctt ctgtccaaaa attcagcagt gtagcgttgg
     6241 cagacaaggt gtatgtttta ggagcgcccg aaatggtttt gcgcgatcaa ttgccggaat
     6301 atgcggaaga gtttgtttct ttcgctgaaa aaggctatcg cgtgttggtc tttggtgtgt
     6361 acgatgggat tcttgaagaa ccagtattga cagaagcagt cacaccatta ggctatattc
     6421 tgattgctaa tcctatcaga aaagaagcaa gagccacatt tgattacttc aaaaaacagc
     6481 aagtagccat caaagtgatt tctggagata atccgctcac cgtatccaat gtagctgtcc
     6541 aagcagggat ttcacatgct gatcagtacg ttgatgcatc taaattatca gaagaagaat
     6601 atgaagcagc tgtcgaaaaa tatacagttt ttggacgcgt caagccagaa caaaagaaaa
     6661 tcttcgttca attgataaag cgtaacaata cagtagctat gacaggtgat ggcgtgaatg
     6721 atattctagc catgaaagaa gcagactgca gtatagcgat ggcttccgga aatgaagccg
     6781 ccatgcaggc ctcacaagtg gtcttacttg attctgactt ttcacgcatg ccagaagttg
     6841 ttgcagaagg acggcgcgtt gtgaacaata ttgagcgatc agccagcttg tttttagtga
     6901 agaatatttt ctcctttttg ctctcactgt tttcagtgat ctttgctctg acctatcctt
     6961 tagaaccatc acaaatcaca ttgattagtt tgtttactat cggacttcca tctttcttgc
     7021 ttgctctaga agaaaacaaa aagcgaatca gagggaaatt catcatgaat gtgatggaaa
     7081 aagctgtgcc aggtggacta acagatatga tcgtagtcgg tgcgttggtg atctgcgggg
     7141 tgactttgaa tctaaataaa acagatgttt ctacagcatc taccatgctt ttgattgcag
     7201 tagggttcct cgttctctat aaaatctgtt caccgctgaa taaattcaga agtcagatca
     7261 ttcttttctg tgctagcggt aacttttttt cggtcatctt tttgcataag ctgttttcaa
     7321 tcaccggtat ctcagctgta tcacttttgc tgttgagcat tctatttttc tcggcagatt
     7381 cgatttttag gcatttgacc acattggtag aatatttgtt tgaacgtaaa aatgaaaaag
     7441 agcaaaagcc gtttagtcgc gtagctaaaa aatttctatc gatatttaaa cgagaaaatt
     7501 gacgaaaagt atctcaaaaa agagtaaaaa agaacaacca ctcgtgtatc tttcgaagca
     7561 ggatgagtca tccaacttta aaacgcacga gcagttgctc ttttttacat tttcggaatg
     7621 gtaacggtga aagtcgaacc tgttccaaga tgactgtcta cagtaatcgt accattaagg
     7681 agttgcacgt agtcttttac aatcgctaac cctaatccgg tcccgcctga atgtcggctt
     7741 cgcgccttgt ctacgcggta aaaacgctca aagatccgtt cctgatcctc aatgtcgata
     7801 cctataccaa agtcttggac agaaaacgat agatcatctg ttgcctgata gcggataata
     7861 atctcgctgt cgctttttga atattggaca gcattttcaa tcagattttt gataattgga
     7921 taaaggatat ctgttttagt agtaaatggt tcgttctttc caatcaatcg aatcgtcaac
     7981 cgtttctttt cgatgattgg ctgataattt tgaacgattt gctggaaata aggttctgta
     8041 taaattgtct ggatctcgta agaattctcg ccatcttttg acagctggat gatttcccga
     8101 atcagtttat ctaaccggat cgcatctttt tgcatgatct caagaaaaga agtcagagtt
     8161 tgcgggtcat cttttgcacc atccagtaaa gtctcggtaa aaccaatcag tgaagtcaca
     8221 ggagttttta attcgtgaga gacgttgcca acgaaatcct tttgtagctt ttctaaacgt
     8281 cgcactttcg ttaagtcata cgccacccct agaatctgtc cggtaccttc tgaattagta
     8341 aagtagcgca aactcaagtc taatgtctgc cgaccttctg taagggtgat ctcctgatgg
     8401 atcagcggat gctcaggagt cacttgatga atcagctgaa tgagttttgg ctcttgaatg
     8461 acttctgtgt accgctgttc aggttgatag cttaccacgt ttaaatgtag ctgcatcttt
     8521 ggattaagca gtagtaaacg agaatcagca tcatcaatca ggaatacgcc aatcatcagt
     8581 tcgttcagta acgtatataa ttgctcttct gtggtagtac acgcccgata catcttactc
     8641 atttgttcgc tcaacgcatt aatcgtctga tacaattctt cccattgatc gggtgtttgc
     8701 atgattactt ccgcctgatt aggattttgc accatttttt ttagtacggg cagcacggtt
     8761 ttcaatggct ggtttttttg atagatcaga taatagatca ttcctgcaag aacaaggaag
     8821 aaagacagaa agaagaaaaa gacccaacgg cgaaaactct cagttctcgg taaaaaaacg
     8881 cttgtcggtt ctgcgatacg taaaatggct tctaactggc cacttttttt gactggtaat
     8941 gcgacatata aaagatcctc attcaaagta gtacttttgc gcaaagcgct acctaggttc
     9001 ccaccattca atacggcttt gatttcggga cgggagtttc gctgttcatt caatgtttca
     9061 ttgtttgtgt caaataagat ctttccagta gcatccatta aagtaatccg ttcgttcgac
     9121 tgatggacga attcttccaa agcagttttg ttttgcgctg cttggaggtt ttcgacatct
     9181 aattgccgga tcagcagttg tgcttttttt gtcaggtagc tttcttgctg ttccacgatc
     9241 tgctgttgaa aataatggga aatcaattgc cagccaccaa aaaacaaact aactaaaaga
     9301 ataagaaaga agagacgttc ataaattttt ttccatttca tcgtttgggt tcctgaaact
     9361 tatagccaaa tcctctaata gtcaccaagt actttgggtg ttttggatct cgctcgattt
     9421 tttctcgcaa atgactaacg tgtacatcta cgattcggct ttgtcctgcg aagtcaaaat
     9481 tccaaatgcg gtctagcaat gtgtctcggt cgatcacacg gtcttttcgt ttcatgaaat
     9541 aaacaagtaa ttcaaattct ttcggtgtta gttcaatcag atggtcgtct acggtcactt
     9601 gataattggt caaatcagca gtgatttgtc caatcgatag atattcaggc tcagcttcat
     9661 cttttgattg cttacgaggt tcaattcgtc tgaatattgc tttcatacgg gctaatactt
     9721 cgcgaggact aaatggtttg gtcaaatagt cgtcagcacc tatttctagg ccaatgatcc
     9781 gatccacttg gtcatcttta gccgtcagca tcaaaatcgg tgtttcattt ttttcttgac
     9841 gcagccgctg agtgatctcc atgccatcca tcgttggaag catcacatct aaaatgatga
     9901 aatcaaatga ttgttctaat gctaattcta atccttcgcc tccatctgtg gcactggtta
     9961 ccttgtagcc ttctttttcc aaattgaacg tcaagagcgt tacaatagaa ggttcatcat
    10021 caacaactag tatttttttc attcaaatct cctttaaata ggtttcattc tgtttatatt
    10081 ttagcataga atcagtacaa agggctattt tacaaaagaa ataaatggta taataggaag
    10141 gcactttgct gaatagaaag gaagagcagt caatgattgg aatcagtgca tgtttaggcg
    10201 gtctggcctg tcgctatgat ggacagaaaa aagaagtacc agaattgatg gaactagttg
    10261 aaactggaga agctgtcatg gtctgtccag aagtgatcgg cggattacca attcctagag
    10321 atcccgctga aatcattggt ggaaatggat tcgatgtgtg gaaagatcaa gcaaaagtat
    10381 ggacgacaag cggcgaagat gtaacggaag cgtacaaaaa tggcgcgatc aaagcctatc
    10441 aaaaattgca ggaaaaacac attgatctag tcatcatgaa ggaaaaaagc ccttcatgcg
    10501 gaacccattc gatttatgac ggaagttttt ccggaataaa aaaaaatggt gccggagtgg
    10561 ctactgctta ttttattcag caaaaaatga ctgtgctctc tgatgaagaa tggctgaaaa
    10621 ctagaggtga gcagaatgga aatcgaaaag accaatcgaa tgaacgcgct ctttgaattt
    10681 tattcgacct tattgacaga aaaacaaatg aactacatgg aattatatta tgcagatgat
    10741 ttttcattag gtgagatcgc ggaagaatac gaagtaagcc gacaagcagt atatgacaat
    10801 atcaagcgga caagcaagat cttggaggat tatgaaaaaa aactccatct tttttctaat
    10861 tatattgttc gagaacaggt attggaaaat atgactgcat atattacaga taagtacccg
    10921 gaagataaaa aactacttga atatgtacag caaattcaag caatcgaaga ataaataaaa
    10981 ggaatgaaga aaatatggca tttgaaagct taactgaacg tctccagcag gcgatgggaa
    11041 aaataagaaa aaaaggaaaa gtatcagaag ctgacgtaaa agaaatgatg cgggaaatcc
    11101 gccttgcctt actagaagcc gatgttaact tgcaagtagt caaagatttt actaagcgcg
    11161 tacgcgaacg tgcggtaggg gcagaagtgc tggaaagttt atcacctgca caacaaatcg
    11221 taaaaatcgt tgatgaagaa ttgacgatca cacttggttc tgaaacagca gagttaaata
    11281 aatcaccaaa aataccaact gttatcatga tggctggtct tcaaggggca ggtaaaacga
    11341 cctttactgg taaattagcc aattatttaa agaaaaatga aaatgctcgt ccgctcctaa
    11401 tcgcagggga cgtatatcga ccagctgcga tcgaccaatt gaaagtatta ggtcaacagc
    11461 tagacgttcc tgtatttgat atgggaactg aagtcagccc ggtagagatc gtccgtcaag
    11521 ggatggagtt agcaaaagaa aagaaaaacg actatgtatt gatcgatacg gcaggacgtc
    11581 tgcatatcga tgaaacattg atggatgagt tgaaacaaat caaagaattg acgcaaccaa
    11641 atgagatttt gcttgttgtc gatgccatga ctggtcaaga tgccgtcaac gtagctgata
    11701 gcttcaacca gcaattaggt attacagggg tcgtcatcac taaacttgat ggggatactc
    11761 gaggcggggc agcactatcg atccgctcag tgacaggcgc accaatcaaa ttcatcggtt
    11821 ctggtgaaaa attgactgac ttagaagtat tccacccaga tcgtatggct agccgtatcc
    11881 ttggtatggg ggatatgctg acattgattg aaaaagcgca gcaagactat gacgagaaaa
    11941 aagcggaaga acttgcacag aaaatgcggg aaaattcatt cgatttcaat gactttattg
    12001 aacagcttga tcaagtgatg ggtatgggcc cactggaaga tctaatcaaa atgatcccag
    12061 gaatgaatca agtccctgga atcgaaaacg tcaaggtaga tccaaaagat gttgaacgca
    12121 aaaaagcgat ggtttattct atgacgccag cagaaagagc aaatcctgat ctgttgaacc
    12181 caagccgtcg tcgccgaatt gctgccggtt ctggaaacag tgttgttgaa gtgaatcgaa
    12241 tgatcaaaca attcaaggaa tcaagaaaaa tgatgcagca aatgtccaaa ggggatatga
    12301 acatcccagg tatggaccaa atgtttggtt caggcgtcaa aggaaaacta ggcaaaatgg
    12361 cgatgaatcg aatgatcaag aaaaataaga agaaaaagaa aaaacggaaa taagatgaaa
    12421 aaaacagctt cggtacagac tgaaaatgtc tactgccgga gcttttctat cagcaatttt
    12481 tattctttac taatacaatt actctaaacg aagaggtggc acagatgaga tgtccgtgga
    12541 gtgaacaaac agaaagtatg cggcaatatc atgatactgt ctggggtgtt cctgaatatg
    12601 atgaccaaaa gctgttccga aaattgatgc ttgatattaa tcaagccgga ttgagctggc
    12661 agacgatttt aaataaaagt gaagcattcg atgaagcata tgatcgattc gatattaaaa
    12721 aagtcgcaaa ttatggagaa acaaaaatca gtgaactaat ggaaaacaaa ggaattattc
    12781 gtaaccgaag aaaaatcgaa gcagccgtcc aaaacgccaa agcagtcttg aaaattcaag
    12841 aagaaatcgg cagtttttca gagtatcttt ggtcgttttc taatggaaaa atcgttgatt
    12901 cttcttatca ttcacaagaa gaagtcccaa caacaagtcc tctttcagat gaattagcaa
    12961 aagatctaaa gaaaagagga tttaaattta tcggaagcac aacaatctat gcttttttag
    13021 aagctgtcgg gatcatcaat gatcaccttg acagttgttt ccgcaaagaa gaggtcgtac
    13081 gtatcggcag aaagggcgaa taaagcatgc gaaaatcata ttttatggtg ctataagttt
    13141 agatggctat ttggcaacga aaacggatga tcttcaatgg ctttttgaca ctccaacagg
    13201 taagcaaacc acttatgaag ctttttatga aacaatcgat acgaccatca tgggcagaaa
    13261 aacttatcag gaagcaaaaa aatatttgga gaccgaagca atttatccag agaaaaagaa
    13321 tttcgttttt tccacccacg cacaattaca attgccagat gctgaggtcg taaacgaaga
    13381 tcctgttgct tttctaaaaa atctacaaat gacagaagga aaagatatct gggttgtggg
    13441 tggcggtcga ttgatcaaac cgctattgga acatcaaatg attgatgaat ggtatatcca
    13501 gattacccct gtattattag gggacgggat tcctttattc caaaaaggaa catatgaagc
    13561 gcgttttgaa atgctagaca cgacacgatt cggtgaattt atcgaattgc attatgtacg
    13621 aaagtagaag taaataaaat aaaaaaggca actatatgca gaaatgtcct gtacatagtt
    13681 gcctttttta ttaccgttat gctttttact ctgttaattt gttagaaaaa tctagatacg
    13741 catctaaaat cgtttggaag aaacttaatg ttccttcaac gatattacca ttttcatcaa
    13801 ttagattcgc aacgtttccg atatatgctt ccggttgctg caaggttggc acattcaaaa
    13861 agacaagtga ttggcgtaga tggtggtttg cgccaaagcc gccgatccca cctggtgatg
    13921 cagtaacgac taaacctggt ttatgatccc aaacactgtg tccataaggt cttgagccta
    13981 catctaaagc atttttcaat actgctggca cagaacggtt gtattcagga gtaacgaaaa
    14041 cgacaccgtc tagtcccctc acttcctcac gaaaacgagt ccattcagca ggagcctgtt
    14101 ctggagtttc gagatcctca ttgtaaaatg gcagatcatc gatttttaca aatacacttt
    14161 cgtacccttc aggaagcaat ttcgcaaaag cttctgctac ttttttgttg taagaatctt
    14221 ttcttaaact accaataaaa aatccaattt tttttgtcat acgatttttc ctccttcaaa
    14281 ctatctataa taatcttaca aaagataagt aactggagca aataaaaaca cttactgaca
    14341 aaagctacat agaagataga ttacttattt ttaacaaaaa agaagtctaa aatcttctat
    14401 tttctaaaaa aaatcgaatt taatcaagct gtaaagaaaa aaagctttac agggtaaaaa
    14461 aaaactgtta cactacatct tgtgaataaa acaatggagg tggaaataaa taatggcagt
    14521 taaaatccgt ttaaaacgta tgggttctaa aaagagtccg ttttaccgta tcgtcgtagc
    14581 tgattcacgt tctcctcgtg atggacgttt catcgaaact gtaggtactt acaatccttt
    14641 gaaagaccct gcagaagtag ttttaaaaga agacttagtt cttgactggt tatcaaaagg
    14701 tgcacaacct tctgacactg tacgtaacat cctttcaaaa gaaggcgtta tgcaaaaaca
    14761 ccacgaagct aaattctcaa agaaataagg tgaccggata tgaaagattt aagcgactta
    14821 gtcttaacaa tcgttcgtcc gctagtcact tatcctgatc aagtcaagtt agacgtcgta
    14881 gagtcgaaag acttttacga gtacaatcta acagtggctc ctgaagatat tggccgtatc
    14941 attggaaaac aagggcgtgt tgctaaagca atccgcacaa tcgtttacgg tgttcggatc
    15001 aatgcaccga aaaaagtgcg tttgaatatc atcgatgata aggaaaagta aataaacgtg
    15061 ctgtactcga attttcgagt gcagcttttt tgtttttttt attaattgaa gaaatgatta
    15121 tttggcaaaa caagcaagaa agcgtatcct tataggagga gggagtgaac agccaatgag
    15181 aaagaaaatg ttatttattc catttgctct attgttaagc gcttgtagtt cggttactca
    15241 agaatcagac aatacacatc tatcaagcag tatatctgaa actgttacca gtccagaaaa
    15301 aagtagtacc aaaacggctt ccaccactga acaaacaatg gctacctcaa ataatgagaa
    15361 aaagactgct ttagaccagt tgaaagaaca acagccaaat gttcccatgc ctctagatgt
    15421 accagtctct tcaggctatc tcaatatcgc agcgacacat acaaagcaag gttattctat
    15481 tttatattac agaacagatc gtcccctcgg gttgaatgct gacgaattga atcaagaaac
    15541 gcctattgca acctatctat atcaatatgg gtttgcttct agtcaagaaa caatccaagt
    15601 tttgcagcca tttgagatcg acacaaatgg tcagcaagtg gacttaggtt ctcgaatcac
    15661 agggtatcag caaggtgcag caggttcaag ttttcttgaa tggcaagaag gaaactggcg
    15721 tattcgaatc cgtgggaata atatagaagg ccaagatccc ttactattag ctaaagaaat
    15781 cgtagcttat ttggaagaaa acagtctacc agcacctgaa caatttggta aaattactgt
    15841 tgatatgggt gatacgacga atcgagccgt agaagtaagc tggcaagaac cgaaaaatgc
    15901 ctatacgatc actcatcaag atcctatgtc tgcgttgaag atggcagttt ctatgaagag
    15961 gttgtgaaat cagcgcgctg atctgagccc atcatttaac tccaagtcac aggaagtaat
    16021 caaaaatagc acgccgcatt tttgcataat tttggcttaa taccttaaaa gaaaactaga
    16081 attgcctctt cacacatgct aaaataaaac agacaaaaaa gaaatgggga tataagttga
    16141 ctgaatactt gaatgtagga aaaatcgtaa acacacaagg tatcaaaggc gaagtccgtg
    16201 ttatctcaac aacggatttc ccagaagaac gttacaaaaa aggaacggtg ctaacactat
    16261 tccaagacgg aaaagcacct gtggaattaa cagtcaaaag tcatcgcaaa cataaaaatt
    16321 ttgacttatt gagttttgaa ggacatcctt ctatcaatga tgtggaaaaa tatcgggatg
    16381 gcatattaaa agtgtcaaaa gacaactctg tagatctagc tgaaaatgaa ttctattacc
    16441 atgagatcat cggtctgcat gtattagaag atggaactga gttaggtaaa gtaaaagaaa
    16501 tcttgtcacc aggtgccaat gatgtttggg tcgttcaacg tccgaaaaaa gctgatatat
    16561 tgcttccata tatcgcttct gtcgtcaaag aagtcgattt agaagctgga gtggtccgtg
    16621 tagaaattcc agaaggactg attgacgatg aagattgatg tattgacttt atttccaaga
    16681 atgtttgaag gtcctatggg ggaatccatc atcggtaagg ctgtagataa aggattatta
    16741 gatatcaata tctctaactt ccgcgattat tcagataaca aacatcagac agtagatgat
    16801 tatccatacg gcggtggagc aggtatgctg ctcaaagtcc agcccatcta tgataacatc
    16861 caagccattg aaaaagctgc accggatgtc aaaaaaagag taattcttct tgacccagct
    16921 ggtaaacgat tcgatcagaa aatggcagaa gaattttcac aagaagaaca cttagtattc
    16981 atttgtggtc attatgaggg atatgatgaa cgtatccgca cattagtgac agatgaagtt
    17041 tccttaggag attatgtcct tactggggga gaattaggtg cgatggtcat gatcgatgca
    17101 acagttcggc ttttgccaga tgtgttaggg aatcagactt cagctcaaac ggattcttat
    17161 tcaaccggtt tattggaaca tccccaatat actcgcccgg cagaatataa agggatgaaa
    17221 gtaccagaag tattgacaaa tggaaatcat aaattgattg aagaatggca attaaaagaa
    17281 tcactaagaa ggacctatca acgtcggcct gatcttttgg aaacacttga atggacacct
    17341 caaatgacga aatttttaga agaaatcaag aaagaagaac aagaaaaaac agcagatgaa
    17401 gccaagtgac tttttctaaa atcttcttta cagtaggttg ataatatgtt agtattttat
    17461 ggtgagtgca aaagcactta actattacga tattccgctg tgagaaaagc tcataagaat
    17521 atttggaata aggagaagaa aaccatgaat ccattaatcg aagaattaac aaaagaacaa
    17581 ttacgttctg acatcccagc gttccgccct ggtgacactg tgcgtgttca cgcaaaagtt
    17641 gttgaaggta ctcgtgaacg tatccagtta tttgaaggtg ttgttatcaa acgccgcggt
    17701 gctggaatca gcgaaactta tacagtacgt aaagtttcta acggagtggg cgttgaacgt
    17761 acattcccat tgcatacacc acgtgttgca aaaatcgaag tagttcgcta cggtaaagta
    17821 cgtcgtgcaa aattgtacta cctacgtgca ttacacggaa aagctgctcg tatcaaagaa
    17881 atccgtcgtt aatcattgtt atcagactga gaaagaaccc ttggtattca agggttcttt
    17941 tttcttagca tgtaatttga acaccctgat ccagtttttt ctttaattat tggtagggga
    18001 gaataatgga ttagaataaa tctacctata agtagtagta aaaaaaagag cactatgata
    18061 atatctttct taagagtaac cgctttaata aaaaatccag aatattctaa cataaatgga
    18121 gtattcttag aatcaaaagg agaaagaaga tggtttatac ttatacggag caagaaaaga
    18181 tgaaagtttt agacacattc atgaatgatg gaaaagtaaa acaagtacca agttcaacaa
    18241 aaaagaaata catcctattg aaagaagtct tgaaacgctt tgaccatgga gtgacttata
    18301 cagaaacaga ggttaattcg atactgctga acgtattttc tagtggcgat tatgtcgaac
    18361 aaagacgtta tctaatcaca tttggctttt tcaaaagaag ttcagacggt cgggcatatc
    18421 agatgatggg aattgaaaat tagaagtttt aatttatact cattgaaaaa agttcaagta
    18481 tgcgatattg gttctacacc gcatacttga actttttttg tcatctgtat ctataataca
    18541 aagccaagaa cgttattcaa aatatggata gctatgataa aagctaatga gcgattcgca
    18601 gttaaataag caatcgtcag taaaatcgtt ccaggagcgt acatgaaaaa atcaattgga
    18661 tgcgttacat gaataaagat aattctcttt tatttgtacg aataaatacc aaaacgtacc
    18721 tcctaaaatt agattttgga cagatgccct ttaaaaagat aacaagattt cgttcttgaa
    18781 acaatatata tgcttttatt ccaatgaggt tgtgaaaaca gtattttgtc ctgagcgtta
    18841 gaaaattgaa aatggggaat agcaactcgt actttaccat tttttaagtg aatacaagat
    18901 cagctaattg aacaccgttt attcgtgatg agggacacaa cactgcagtc gacacatttc
    18961 tcttttatgt tcaaagataa caaatattta aaacaaagaa aaatagtaga taatcccgtc
    19021 ctaactcttt tattcttccc tcatagcttc caaatttaag caatacttca attaatcaag
    19081 ttttatcttt ttttttcaat aatcgtaaaa aaagagtatt ttttatttaa aaataaaatc
    19141 tttgtattaa aggacaagac taaaataacc ttagaataaa aagagaaaaa aagccccaaa
    19201 ctttctatac atcaataaaa taataaaaat taaatttaga ataacgtgta aaggattatt
    19261 tgatgatttt ttattgagag gagggatgaa aatgattaag aaaactcaaa ataaaatcca
    19321 acgtatatgt caaaaacatt ttgtttctag actcaaagct gtatctaaaa gaaaatactt
    19381 acatcccatt atgatttcga tcatcttgat ttttactttc ttagggagct tatcaagtat
    19441 ttatgtaaac gtttatacag aaacgtcaaa ttttgctaac caaacgacag aggagacaaa
    19501 tagtccaccc tattctgaaa tacagtccat agaaagcacc aatcagtcta gcaacaacga
    19561 gacaacctca accacatcct cgactcaact gattgatccg acagaaaaag aaatcacagc
    19621 agcaaaagca gcaggggaga aagcttattc agaaacaggt agaagccaga catttagtac
    19681 tgttgcggcc actgcgaatt tcaacggaca taccatacca gatggatata cagtgatata
    19741 tgccaaagat ggagtcattg ttgcggttaa cggatcgatg agtgcggata aaactgcgtt
    19801 acaaggcgta accaaagcaa tcgcttttat tgataaccgt ccagatatcc ataatctgtt
    19861 tattggctcc acagtaaatg gtactactat cacattccca aaaagtatct atatgggggt
    19921 ggctaccgct ggaaatacga tcgattcagt tacacccaat gcggataaaa gttattcttt
    19981 tacaccctca acatggggag ggcttcctgc cggaggaggt atgagtactt tttcaatcgg
    20041 tatacagtta gcaaatgata ttccattcac ggggtactcg atcaaaaatg ggcagatcgt
    20101 tgatggtaag ggaaatgttt caaattttcc aacctatcaa gcagcaacgg ttcaggtcaa
    20161 tgcgaatcgg acaggaactt tttcttatac agtcaatggt ggagcagcaa aaatcggaac
    20221 gtacgggact acattatctg gaatccatgt gggtgacaaa gtggttatca ctccaacagc
    20281 agtaacgggc tattcttttg cacaaacaaa cggttctttc acagccctag aaagtaacgt
    20341 cgatacggtg acctatacag gcaaacaaac accaatcact attaagtatc aagactattt
    20401 tggacagatg attgctcctt ctaaaataat gaatcttact tacggaagtg ctgcacaaga
    20461 cctgacgact aatacgccta ctatcaacgg atataccttt acagctgttt cagcgacaga
    20521 aacaaagaac caatcagcaa tgagtgtttt agctagttta gatacaaatg gaaatgtaat
    20581 cgtaaaggac gcaaatggaa aacagatttc tgaagtcatc ctatattata agacaaatgc
    20641 aacagtatca atcaatgcaa atggcagtaa gtactatgat ggtctttctg ttgtaccgat
    20701 cgttaaatat gcctttaatg ataaaacaga atcaacatcc cttttaaaca atgatctcag
    20761 tattgatcaa atcacatgga atccaactga tttcaaagcg atgaatgaaa agggagttga
    20821 agtaactgcg cctactgaaa ttggaaccta tacgtcttgg caattgacaa aaagcggact
    20881 agctaaacta gctgccagaa caaactattt atttactatc gtgcagacat ctgatgtcta
    20941 tacgattaag caaatcagcg gtgcggtaga gctcagtggc agtaagacat atgatggaaa
    21001 agcaggtgtc ccgtcaatcc atgtcaagct agcagagggt gtcactagtt cgcttactcc
    21061 agtacaagtg gcacttagca gtatggatta cacagcagat gcacaatcag caaaaaatat
    21121 ggttaatgct ggcagctata caattaaact aacgaatagc ggaatagaca aagtcaaagc
    21181 agcaaatccc aagttgtcat ttactgatat agccaacaca tcaggaactt ataccatcta
    21241 taaagctaac gcagtgatta ctgtcgatga cgctgccttt aattatgatg cccaaagtca
    21301 ctcgatttcg gttggaaatc tccacgttac cggtgttgtc ttaggcgaat cattggatta
    21361 taccctaaca gttaacagcc ggacagatat tggatcacaa atagtaacga ttagtttagg
    21421 cgaaggaagt gtaaacaata attatacgat tatcgcaaca gataccgcta agttgacgat
    21481 caatccgact ctcttgcttc cttcgacagg tgggataggt ctactgccct ttgtcttttt
    21541 aggactgatc tttatttttt ctggcttctt ttattttatc catcgtaaga aaaaagcagg
    21601 tgaacagcga tgaaaaaaac aaaaaatgta cgtgtggata tatttgctgt tctctttttt
    21661 atcctactgg tcttttttat aggttctccg actgtgtcag ctagagaatc acctattaca
    21721 tttactttgc ataatcgaat gttcgaaagc gataagatgc caagtatcag tcaaaacgac
    21781 ggaataaata tcccggataa ctttcaagga gtaaaagggt tgaacggcgt tactttcgct
    21841 atatatgatg tctcggatga attttacaag ctgcggtcag aaggaagtag tgtggaagac
    21901 gcacaaagaa aactagcaca aaaaagtgat agtgaaaaaa tactggcaga aaatgtgaca
    21961 aaaacagtag acgaggaaga gggcattgct tcttttagtg catcggacaa agatgagcaa
    22021 ggtcgtgacg ctgtttaccg atttgcggaa ataaagactt cagattaagt aaaagaaaaa
    22081 tcagcaccat ttgtcgttgt gcttcctgtg acagattcat ctaatcataa attgacgacc
    22141 atccacttgt atccaaagag cgaacaaaaa atacctgctg cactcacatt aacaaaaaca
    22201 gtagagaata agcagacaga ttttgcagat ggggataaag ttccttatct catcaccgta
    22261 acaattcctg agaacatcaa cgagatagga acctatacga tcaaagatac agctgatcct
    22321 cagttatggc tagaaccaga aacgatcgat tttttgattg gtggagacaa gattcataca
    22381 tttcacacac aaaaaacaaa acatggtttt gtcttatcag attctggaaa agatcttagt
    22441 tcgtttgctg ggaaaaaatt aacgatccgt taccaaatga cattgaaaga aaacagtgaa
    22501 aaaacgacat ttgataacga tgtacgtttg acgactgaca atcaaacagt agaaacacat
    22561 cttgccatcc aaacaggagg caaacaattt gtcaaagtgg atcggcaaac gaaacaaaaa
    22621 ctagcagatg ctcaatttct agtcaaaaaa aatgaccaat acttagcgca agaaaacggg
    22681 ataaatcatt gggtagccaa agatgattca agagcaacga tttttacttc cagtaaagat
    22741 ggaacatttt ctgtccatgg attgtctttt ggaagttacg aactagtgga gattaaaccg
    22801 cctaaaggat atatattgag tcaatcaacc attctctttg aagttgaaaa aggcagttat
    22861 gatccgcttc atcctatacc attggaaatc atcaacgaac caaaagcaaa tccgacgaat
    22921 aatggaaaaa cgccagttca gatgcagaca aatggtccat caaatgaaaa aaatggagga
    22981 agctttccaa aaacaagcga agagatgctt ggaggtttct caattttagg gttgttgcta
    23041 gtcctttcaa cagggacagc ttggttttat aaaaaacaac aaaaaggaaa caataggagg
    23101 gaaataaaat gaaaaacatc aaaacaaaaa tatggacgtt tttaggaact gctatcatgc
    23161 tgcttccttt cgttctcggc ctaggaactg cagaggtttc taggccgtat cacctacacc
    23221 agaaaatgtt acggttaatt tgcataaatt gaaattcact tcagcaccag aaaatcaaat
    23281 aaacaacgga acggaattga catttccgaa tagcgaaccg ttgaacggcg ttgaattcaa
    23341 cgtatatgac atcactgcta cgtactatcc aagtaaagac acagcagttc cagcagacgc
    23401 tacacccttc gcaagtgtaa cgacttctgg tgaaggatta gctaacctga ctcttccagg
    23461 taaatctgat gggaaagatg ctgtatacgt ctttgtagaa acaccaaagc ccggtgtcga
    23521 aacgtcgcca aatatcgtgt taagcttacc cttttataac ccgaattcat cagaccctga
    23581 caaaccttta gacacgattc acctatatgc taaaaatgtc atcaaagaaa gcaatatcaa
    23641 aatccagaaa gctgggaact tttcaggggt agataagtta gcaggggcgc aattccagat
    23701 caaaaattca gagaatcaat tcgtgaccgg ttttgatgaa aacactggtg tcgctctcta
    23761 tgatcctgct gagtcagcgt tgacattcac aactgatact gaaggatcca tcagtgtcaa
    23821 tggattaata gacggcaatt atactttagt tgaaacaaaa gcaccagatg gttatcaatt
    23881 aaccaatcca caaaaagaaa ctacttttat agtaaaaaac ggaaaattgc aacaaacaac
    23941 cggtatcatc catggcgcag atgaagccaa tcttgggaat ccaaacggtg tagtcaatcg
    24001 ggaaaataca actacggata acacgattac tgtagaaaat gtccaaaact acggtgattt
    24061 ccacttcatc aaacaagatg tgaacacgca agaaaaatta gccgatgcag aattttctat
    24121 tctaagagca aaagatccaa ctgttaaatt aatgaaaaaa atagcaaatc ttgcctcagg
    24181 agaataccca tatgcttggt cagatgaagt cacaggttct gactgggaag aagtgaaatt
    24241 gatttctgat tcagaaggga aattttcaat cgaagggctg aaacaagggg catactgcct
    24301 tcaagaaaca aaagcaccag aaggctacgc attacctaag aatgaagctg cgtacactga
    24361 atttacagta gatgatgatc caacaacttc tgatgaaaca acgatcgata accaacctaa
    24421 aggaatcttg ccttcaactg gtggtatggg gatcatcgta ttcatcttgg taggtactgc
    24481 tttagttgga ggagcagtga tctacttcaa aaaacgccat caagaaacag aagcttaaac
    24541 tattggaaac aaaaatcata cgataaataa acgatagtga ttcaaatggg gagaaaggtt
    24601 gtgacaagtg gtcggtctct tggtattcgc tcaacaaacg gcaaaatagg aggaactatt
    24661 ttgccgtttg ttgagcgaat actcaggtca aggcgctgat ttcacaacct cttcatatac
    24721 atattagaaa ataggtggac atgatgaata aaagcagaat aagaatactg gacatcttca
    24781 tggcaatcat tttagtcgtt gggatcggga tcttttctta tccttttgta gaagattcac
    24841 tgaatgattt tcttgcccag caaatgatca tccattatca aaagcaagca tcgaataaga
    24901 attcagagga aataaaaaaa cagcaggaaa aaatgacaaa gaaaaaccaa cagttggcag
    24961 agcaaaacgt atcaccaggg ataggcagtt tcaaccaagc agttgatgca aaagcattaa
    25021 aagatttacc tagtaatgcc ttttttatgg aacatatgct tggagtcatc gaaatcccaa
    25081 aaatcaatgt cagcttacct atattcgatc agacaacgga aatatttttg caaaaaggaa
    25141 cgtcattatt ggaagaaagt tcttatccga ctggcgggaa aaacacccat gccgttcttt
    25201 ctgggcatcg tggactccca gaagcaaaat tatttacaga tttgcctaag ttgaaaaaag
    25261 gagaccagtt tttcatccag atcaatggaa agacattggc gtatcaagta gaaaaaatcc
    25321 aagtggtctt acctgatgaa gtagattctt tgggtatcca aaaaggcaga gatctcgtga
    25381 ctttgcttac ctgtactcct tatatggtca atacacatcg actgcttgtg acggggcatc
    25441 gtattcctta tcaagcaaaa gaggcaaaaa aagcgatcca aggaattgat caatggaaaa
    25501 aatggaaatt ttttatttgg tttatcggta tactacttgg atcaatcggc ttagtttggc
    25561 tactcatcgc ttatttagat tctttggcca tcgctaagcg aaactatcct ttatcttttt
    25621 atgtaaagaa cacaaacgga cgaccaatcg aaggaatggt cttttctgta aaaacgctca
    25681 acggcaaaca ctatattact agagaaaaag ttccatttgt gaaagcttct gatgaatacg
    25741 gactagtgag attttctgat ttaaaaggca ggaactatcg cttgcaacat gaggagctcc
    25801 tgcttaaaat ccatgtaaaa cataaacatt cgaaacagtt ttcaatgaaa ttgaaaaaag
    25861 gaagatataa actgcgaaaa gaaaaagagg tgtactattt gattgagaaa gaatgaatga
    25921 agatgtccaa aaaagcagag ggaacagact aaatgaaaaa agagagaagc tgacgaaatg
    25981 gacgtgtaaa ctgctatttt tggtttacta tctggaacgc cagcttctat ttttttatgt
    26041 ttcagaagaa ttttattatt atagtataac ttttgaatta gtttccataa catttggagc
    26101 aaggggttaa accacgagct tgagcttcgc ttaaagtggc aggggtatac gtaccatttc
    26161 cacatttatg tgtatggtat tttgaaccgg tcggtgtgac atagacagtt tgttcattat
    26221 tttgctcagg agctgcggct tgtgcctgct gagaggcctg ttcagctgct gcttgctgtc
    26281 gcgcctgttc tgcttgttgc tgtgcgattg cttcttgttg cgcttgttct gcttgttgtc
    26341 gtgcaatttc ttcttgcttt ttccgttctt cttctgcttc ttttgctttg attgtggaat
    26401 caattgcagc aagacggctt gtcaactctt gtttgttttc aggtagcgct tggatagctg
    26461 ctgaagcagt tgcatagttt tcttttgtag gatttgcttc agcttgtgac aaagcagatt
    26521 ccgcttctgt cacttttttt tctagtgcag ctttttccgc tttttgtttc tcttcttctt
    26581 ttttcttttc aatttgttct tgttctttcg atgaatctgc cgtactttcg gagatcgtgg
    26641 tactgctgct ggaagcctga gctgaacttg tgctttgagt agtagacgta gtagcaccac
    26701 acccactcaa caaacttcct gcgaccaaaa acaatgcaac taattttttc actaaatttc
    26761 ctccttaagt aaaaaacaac cgttttcaat aaatgtcctt ttcaattgtt tacttacttg
    26821 ttataataat tgtgttatga atagtgattg aggaaactta atctaatccc gttttgatac
    26881 acgggatttt ttgctatagt tctgttatta agtatgcaat aataaaatat gtacgttatt
    26941 ttattattag attattgaca tttatataat aaacgattaa atgattcata tcaatagaat
    27001 acttaggaaa aaaagagaaa taataacagg tttatgcact attgacggtg tgacaatatg
    27061 atatttgtat ccgttttttt tcttgtatgt agtatagtaa agtagataca ggaggagaaa
    27121 atatgcagac ttttttaaca aaagtttctc aaaagaaaat taaaatgatt catttactgc
    27181 ttgaaacaga acgttggtgt tcaatagaag aactacaaaa cgaattgaag gtatcaagta
    27241 agtctatctt gaattatcta acagatttag aagaattgtt ccaaaaatat cctgataagg
    27301 tcattttgaa gaatgagaat aatcggcgct tttctatgga aaagcaggag aacttcccaa
    27361 tctacattat ttatcttcat ttctacagaa aatcatataa ttatcatttg attgaattca
    27421 tgtatcaaca tcctgagaaa aatttggaag attatgcaga cgctcaatat acgagtgtat
    27481 ccacagtttt tcgttatgct aagttattag taaagtactt tgaaatgacg gacgtcaaag
    27541 aatagtagcc gccagataga aggaaattag cagttgaaaa agctgccctg catcaagtaa
    27601 tacgaccagc caaacggaaa cagtgtctca tgtttttgat ttggctggtc ttattaccgc
    27661 agatgcaagc ttttgccaca cctctttctt gtcatttaca gactcaacta tcaatgctgc
    27721 aagctttccc ttaatgctgt aacaccagta agagttgtca agaccagcag actgactagg
    27781 taaataccgc tcaaaaacaa gattacggca gttaaactat aatgatccat caagaaaccg
    27841 atgacgatag aagaaaaacc accaacagct cgtccaaggt tcataatgaa attattcgcc
    27901 gtcgcgcgga tttctgttgg atacaaacta ctaatcactg cgccatatcc accatacatg
    27961 ccattgataa agtagccgac tatcacagcg gctgctacca aactccactg gctatgggct
    28021 aacacaagta gatagacaga taaggatgaa caaattaaaa acaaagaaaa ggctagttta
    28081 ggccccaatt tatccatgat tatgccaaaa gtcatcatcc ccaaagacat gcctaaaata
    28141 gtactgacca tccacaatga agacccagaa accgaaagcc ctaatcgatt ttgcataatt
    28201 gaaggcagcc aattcattaa cccaaaatag ccggcaattt ggacagttac catgatacta
    28261 aggccacatg tttgccaagc aagatgtttt gattcaaaca gtctgctaag tttggttttc
    28321 ttttcggcag attgtacaga tttgaattcc tttggttcag tcaagccgcg acgaatgaac
    28381 aagaccatca acaccggcag tacacctacg acatacaaca tcttccaacc aaacgttgga
    28441 atgatcacag cagctaaaat cgcagccaaa gccgcaccga cctgcgcacc aataccagca
    28501 accgaagaag ctcgtccaat ttgttttttt gaaaaacttt cggaaatcaa ggacatacac
    28561 gccccgtatt ctcctcccgc tcctacacct gcgataaagc gaaagagata aaccaagtag
    28621 atgtttgaag caaaatacat caataaagaa gcaatcgaaa acagaaggac cgtttgagaa
    28681 aatactttca cacgtccata tttatcagct atgatgccaa aaaaaatacc tccaatgagc
    28741 atccccaaat tagtgatcgt tgaaatgaaa cccgcttgcg taccactaat atgaaaagaa
    28801 gtaatcattg aagataatga aaaagctaaa aacataatat ccatattctc taaagcaatt
    28861 cccgccgatg tcgataataa taactttcgc tgatacgttg tcatttttat accccttttc
    28921 ctaaaatttc cctaaattgt taaaagtata tccaaaaaag aataaaaaaa caagactttt
    28981 ttatttgaaa taatacacaa acaaccgata tagataatcc agcttagttt taatagaaat
    29041 gagtattgac ttggagtaca cttaaagttg tagaataaat aaaatacata agtaaagtgg
    29101 caagaaatta agagaaagag tgatcagatg aatatcaaac aagtcagtga agaaaagggc
    29161 atttcggccg atacattgcg ctattatgaa cgaatcgggt tgattccacc agttaatcgg
    29221 acaaaaggcg gaatccgtga ttatacagaa gaagacctaa aatgggtcga ctttacgatc
    29281 tgtatgcgaa atgccggatt atcgatcgag tctttgattg aatatattcg cctatctagc
    29341 gaaggagaag caactgtatt tgagcggcgt aagcttttga ttgaagaaag tgaacttttg
    29401 acgaaaaaaa ttgctgaaat gcaagaatgt ttggaacgtt tacaaggaaa aatcaagaaa
    29461 tatgatcgtg tgttatctag aaataaaatg gaatgtatca agtaaaaaaa tcaaggagca
    29521 tcgctatgga gttacgctta ctaaaatatt tttggacaat tgcagaagaa ggaacaatct
    29581 ctcaagccgc agaagttcta catcttacac aaccaacctt aagccgacaa ctgaaggagt
    29641 tagaagagga actaggaaca gaactgtttg tacgcgaaaa ccgcaaaatg atcttgacag
    29701 aagcaggtta ttttctaaaa aagccgagca gaagaaattt tagatttaac gaatcaaacc
    29761 actcaagaat tcgagaacag aaaaaaacaa ttattcagcg gccgatttac gatcggctgt
    29821 gtggaagctg ataattcgaa tacattggca ctattactag aaaagttgat ccgtgattat
    29881 cccagcgttc aatttcatat ccacagcgga acaagtgatg atatcacgga gtgactagaa
    29941 aaaagcctgt tagatttagc gattttgcta gatccagtag atacagagaa atacgaaacg
    30001 attttgttac caagaaagga aaaatgggga ttgctcattt tagaaaattc tgttttagca
    30061 aaaaaagacg tgataacaaa agaagacttt gcgaatgtac ctcttttgat ctcaaagcgt
    30121 ccagaaatac agcgaatgtt tgctgactgg ttaggcataa aaaaggagca gttgctgatc
    30181 acaggaacgt acaatttgat tttcaatgta tttgcgctaa ttgagaatca ggtaggtgct
    30241 gctttagtca tagaaggtgc tgtaagtcat ctttcaaagc gagtgacatt cgttccgctt
    30301 gacccaatga ttgaaacgaa ctgcatgcta gtctggaaaa agaatcggat tttatcacct
    30361 gtagtcaatg aattgattca ccgtttcaaa gaagcttttg aacagtaata agtatctcta
    30421 atcgaagaaa tttcaataca aaagcgagac gtatgacagt cttgcttttg tattttttca
    30481 tttttaaatc aaaaaaaata aagagattta cataacttgt taaataagcg cttacaaaca
    30541 taagaagaac ggaaatgaat cagctataat aaccgttgtt ctggattgta atcattacaa
    30601 acaaatgaag attataactt tggaggtgtt cgaaatgaaa gaaaaaaagc aaaaattcgt
    30661 tcaaaaaaca tgccctttat tcaatggttg ggtatgattc tgctgattgt attagcttta
    30721 ttgacgatca ttcctttttt atggatggtt tctgcttcat tcaaagcaaa taatgaagtg
    30781 ttcacgattc cgattcaatg gatccctaaa acttggcatt tagagaatta tctggttatt
    30841 tggtctcgta ttcctttagt gacatttttt aagaatacag cttttttaag cgttgtgatc
    30901 acgttgattc agttgtttac ttctagtttt gctgcttacg ggttttctaa actaaatttt
    30961 aaagggcgcg atattttatt tttagcatat atcggcacga ttgctgtccc ttggcagtct
    31021 tatatgatcc cgcagttcat tatgatgaga aaagtgggtt taacatatac gttgtggtcg
    31081 ttggtgctat tacaagcgtt caatgctttt ggtgtgttct tgttgaagca atactacagt
    31141 agtatcccag attctttatg tgagagtgcg cggatcgatg gcttatcaga gtggggaatc
    31201 tatcgcaaga tcattttacc tcttacaaaa ccggcgattg ccagtttgac gatcatcaca
    31261 ttcgttaata catggaacga ttatatgggg ccattcattt atttgtcttc tacggaaaat
    31321 aaaacaatcc agttagggtt gaaaatgttt attgggctat ttgatgcaga gtacgcatta
    31381 atcatggctg cctcagttgt ttctgttctt cctgttgctt ttatattttt agcgatgcaa
    31441 aaatattttg tagaagggat cgcttcatca ggaatgaagg aataggaggt gattatgaaa
    31501 gagcagcgtt ttgacaaaaa tgtttatatg gaattctttt attggttgta tcaatcattg
    31561 gcaagtagcc tttgtttttg gtgtgtcaat atcttgtata tagcagctgc gttccttttg
    31621 tcgatagatg gaaggaatgt cttttccttt attttttctt tactttttat tggtccaggt
    31681 tgcatcgtga tgataggtat gacagaagaa ttagcaaaag aaaaaagttt ttcaccagta
    31741 cgtttgttca taaagacgtt tcgccaattt tggctaaagg gattttttta ttggctattt
    31801 gcttggatag ttagtgtgat aatgattttt gattgtttct tttttatacg tttttcttat
    31861 ggaaaatggt tgattccgtt gtttgtttta cttgcttgtt tatcagtttc ctttagcatc
    31921 aactactggt attttcaggt gagaaatcca gcgtcgaaac caaatcaagt tctacggata
    31981 gcgttctact atacgttgaa aaaatggtat gtgagtttac tagatttttt actattgaca
    32041 agtttgtttc tcttcttttt cgtaaagccc caatggtgta ttctactagg tccttctatc
    32101 gtatttggtt tgatttactt caacaatcgt aaattgatga gaactatgga tctgtagact
    32161 ttataaattg aaactttcaa ttaagaatga cagtttttat gtaaaaactg tcattctttt
    32221 tcattttttg aaacatatgg ctaaacaaat gaaataaaac gtgctatact tttgaatgaa
    32281 acaggtttag aaactgtatc aattatttgt gattatttct aactaataat taaaaataaa
    32341 gcataaaaag gacgatgttc aatggacgaa aaaatgaaac aaggttcgaa atctgtagta
    32401 gaaagtttga ttaatcatca tgttgattat gtattcggta taccaggtgc aaaaatcgat
    32461 ggtgtattta atgaattaga ggatcaaggt cctgaattaa tcgtgactcg tcacgaacaa
    32521 aatgctgcat ttatggcaca agcaatcgga cgtattacag gagagccagg agtagttatc
    32581 gcaacaagtg gtcctggtgc tagtaactta gctacaggtt tggtaacagc gacagcagaa
    32641 ggtgacccag ttttagcaat tgccggacaa gtaaaacgaa gcgatctatt gaagttgacc
    32701 catcaaagca tggataatgc agcactgttc cagccaatca caaaatacag tgcagaaatc
    32761 caagatccag aaacaatttc agaagtgatt gccaatgctt atcgtatggc taagagttca
    32821 aaaaaaggcg cgagctttat cagtatcccg caagatgtag tggatgcacc tgtccaaggg
    32881 aatgtcatca agccattgag cgatcctaaa ttaggttctg cttctgcaga tgatatccgt
    32941 tacctagctg aacgcattag agaagcaaaa ctaccggtac tattagtagg tatgcgagga
    33001 tcaagtgaaa aagaaacgtt agccatcagg caattagttg gaaagacagc attgcctgtt
    33061 gtagagacat tccaagcagc tggagtgatc tcacgtgaat tagaagcgca tttctttggt
    33121 cgtgtgggtt tatttagaaa ccaaccagga gatatgcttt tgaaacgaag tgatctagtt
    33181 attgctattg gctatgatcc aatcgaatat gaagcaagaa actggaatgc ggaaaaagat
    33241 gcgcggatca ttgtgatcga tgaagcgcca gctgaaatcg atccttttat gcagcctgaa
    33301 agagaattga tcggtgatat ctcagccact cttgatttat tgacaggttc attagagcct
    33361 caacaagtgt cagaagatgc aaaagaatat ttagcatctc ttcaagcaga attaacggag
    33421 cgggacattg ttcaatcaaa aggagaagca ggtatcttgc atcctttaga agttattaac
    33481 acgcttcagt caaaagtaac agatgatatg actgttaccg tagatgtagg tagtcattat
    33541 atttggatgg cacgccactt tagaagttat gaacctcgtc atttgttatt cagtaatggt
    33601 atgcaaacgc ttggtgttgc attgccatgg gcgatttctg ctgcattggt gcgtccaaat
    33661 acacaaatcg tatcagtttc cggcgatggg ggatttttat tctctgccca ggatttagaa
    33721 acggcggtac gtaaaaaatt gaatatcgtt catttgattt ggaatgatgg acactacaat
    33781 atggtagagt tccaagaaaa aatgaaatat cagcgggcgt caggtgtaga ctttggtcca
    33841 gttgattttg tgaaatatgc agaagctttt ggcgctaaag gaatccgagc tacaagtgta
    33901 gaggaattag aaaaagcttt agaagaagga tttgcgacag aaggacccgt aattattgat
    33961 attccgattg attaccgtga taatgagaaa ttgggagaaa caatcttacc agatcaattc
    34021 tattaaggaa gtgtcgacat gactgaaaaa atcttatacc agcacgggac attaggagct
    34081 ttgatggctg gcttgatgga tggaacagaa acgattgctc atatattaga aaaaggaact
    34141 ctgggattgg gaacattgca tgggcttgat ggtgaagtca tctttttaga tggcgtagct
    34201 tatcaaggaa gatcagatgg ctcagttgcc caattagatg gaagtgaact taccccctat
    34261 gcagcaatta cagattttac gccagatact agtttttctg tctcaaaaac tgcagatgga
    34321 gaacaattga aaaaagacat attagtaaga gaagccgggg aaaacctatt tttggcagtg
    34381 aagataactg gattattcaa aaatatgcac atccgtatca tgccgaagca agaaaaacct
    34441 tacagaagac tagcaaaaat ttcagagtct caaccagaat tccaacaaag caatgtccaa
    34501 ggaacattag tcgggttctt tacgcctgaa ttattccaag gagttgctgc agcgggattt
    34561 cacttgcatt ttatcgatga tacacataca tttggcggac atgtaatgga ttttgaagtg
    34621 gctgaaggaa aagttgagat tagccgcatc tcgtcccttg tacagcattt tccagttgat
    34681 gatccgactt ttgttcacga aacgattgat tatgctgatt tagcagcaga aatccaacaa
    34741 gcagaataga aaaagacagc gagatgcgtt caaggtgatt aacctgacgt atctcgtttt
    34801 tttgaggagg aaacctagcg tttacaaaaa aactgagcta taatcttctc catagatcaa
    34861 aaaggagcgg tttttatcat gtggacagaa aaacagaaaa aagatgcata cgaaatttta
    34921 ttattacagc aacaaggatt attagaagca gaagataact ggttagcaaa tttagcaaat
    34981 tcatctgcat tgttgaatga gactttgcct gagactgtct ttgcaggata ttatttattc
    35041 gatggtaatg aattgatttt aggaccgttc caagggcgag tttcttgcac acgtatcaag
    35101 atgggaaaag gagtttgtgg agaatcagct gaaaaacaag aaacattgat cgttgatgat
    35161 gtcaaaaccc atgcaaatta catttcctgc gattcagccg cacaatcaga aatcgtagtg
    35221 ccaatggtaa aagaaggtaa tttaatcggt gttttagata tcgattgcgg agtaacgaaa
    35281 gggtatgatg aaatcgatca agcatttcta gaaaaatatg tagatctttt attagcaaat
    35341 tttaatataa atgctttttc atttattaat aactaaaatc gtctattgaa acaaaaaaga
    35401 agagaaatca agaataaaaa gagccggaaa gacagtgggc atttctgttt ttcggttttt
    35461 ttattttttt ataaaatcac aagtgttatt gattttcata atcatatttt aatggtatta
    35521 tcattttaaa taatggaaaa acattaagga tggatgaaat atgaataacg aaactatcat
    35581 tttaggaaaa aaatatattt gccaacctat tggcttgaaa caaaaagtgg ttggagaagt
    35641 aatcagtaaa ttagaaaatt gtgttgtgat ctgcgtagac gaatatcatg acgtcgatcg
    35701 caatgaaata ttagaaaaat gcggaaaagt agtggcaaaa tatactcacg tttatgagtt
    35761 ggaaacaaca gaatatctat ataactatag caacaaatat gaacatactt tagtttcata
    35821 aagatttaaa taaagtgcct tcaaaagcga gaagaccaag cttttgaagg cactttattt
    35881 agttggcagt gattgttcat gatttttgat ttattcaaaa ggttcgccta gagaatctgt
    35941 ctctgtaacg aggcctggtg gagaaactcg ataaaaacct atactgccag aactgtccta
    36001 ttttcggata gacaaactag tagttttaaa aagatcatcc gatccaatca tttcaaaaaa
    36061 tgcaaaactg atatcaggat catttagctc aggcttgtta tcgtaaagca tttgtaaagg
    36121 ttgcatttag ttaggagtaa acgcgaaact atcatcatta tttgctgaag aagatgaaga
    36181 agctaattca gagtttgttt gaaataaagg agacgtgctg acagtttctt taccctgttt
    36241 tttgcagagg tagaaacttt tatatcggaa gtttctaccg gagaattttt ctcatttgta
    36301 gaaattgttg aatcgatact attcgaaatt tgcgtatctg aaggtatgtt ctttgatgca
    36361 gaagtcccac aagcagtaag taacaataaa tttgataaac tgataaacag aattcttttc
    36421 attatgtaca cactccttat agtatcgttt agcatacacc tatgctcagt attaggcaaa
    36481 atcaatgcaa aactatcaag tcttttatag tatctattag tcttagtaat acatatatgg
    36541 agagggtgat atcccagttc aaaccagata cattggttac catctgtatt aacgattatg
    36601 cctctaaacg ctttttttat gaaaaaattt ataagtgaaa acgtaggtat gatattatct
    36661 agaggtaatt tttttgggta tttaaatagt tgctaggagg atag
//
LOCUS       DAIGTA010000023        36567 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.023, whole genome shotgun sequence.
ACCESSION   DAIGTA010000023 DAIGTA010000000
VERSION     DAIGTA010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.023"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(25..1521)
                     /gene="lysS"
                     /locus_tag="NOB43_001238"
     CDS             complement(25..1521)
                     /gene="lysS"
                     /locus_tag="NOB43_001238"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCI0982108.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="NOB43_001239"
     CDS             complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="NOB43_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCI0982109.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="NOB43_001240"
     CDS             complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="NOB43_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCI0982110.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="NOB43_001241"
     CDS             complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="NOB43_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCI0982111.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="NOB43_001242"
     CDS             complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="NOB43_001242"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCI0982112.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="NOB43_001243"
     CDS             complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="NOB43_001243"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCI0982113.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8052..8522)
                     /locus_tag="NOB43_001244"
     CDS             complement(8052..8522)
                     /locus_tag="NOB43_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HCI0982114.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8568..8993)
                     /locus_tag="NOB43_001245"
     CDS             complement(8568..8993)
                     /locus_tag="NOB43_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HCI0982115.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9060..9329)
                     /locus_tag="NOB43_001246"
     CDS             complement(9060..9329)
                     /locus_tag="NOB43_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HCI0982116.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9340..10935)
                     /locus_tag="NOB43_001247"
     CDS             complement(9340..10935)
                     /locus_tag="NOB43_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0982117.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="NOB43_001248"
     CDS             complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="NOB43_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCI0982118.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14488..15048)
                     /locus_tag="NOB43_001249"
     CDS             complement(14488..15048)
                     /locus_tag="NOB43_001249"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCI0982119.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15401..16375
                     /locus_tag="NOB43_001250"
     CDS             15401..16375
                     /locus_tag="NOB43_001250"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI0982120.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16545..17945
                     /locus_tag="NOB43_001251"
     CDS             16545..17945
                     /locus_tag="NOB43_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HCI0982121.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18023..18745)
                     /locus_tag="NOB43_001252"
     CDS             complement(18023..18745)
                     /locus_tag="NOB43_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0982122.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18824..19330)
                     /locus_tag="NOB43_001253"
     CDS             complement(18824..19330)
                     /locus_tag="NOB43_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI0982123.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19453..21252
                     /locus_tag="NOB43_001254"
     CDS             19453..21252
                     /locus_tag="NOB43_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HCI0982124.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21320..22894)
                     /locus_tag="NOB43_001255"
     CDS             complement(21320..22894)
                     /locus_tag="NOB43_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0982125.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="NOB43_001256"
     CDS             complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="NOB43_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCI0982126.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="NOB43_001257"
     CDS             complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="NOB43_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCI0982127.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24671..25309)
                     /locus_tag="NOB43_001258"
     CDS             complement(24671..25309)
                     /locus_tag="NOB43_001258"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HCI0982128.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25310..25960)
                     /locus_tag="NOB43_001259"
     CDS             complement(25310..25960)
                     /locus_tag="NOB43_001259"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCI0982129.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="NOB43_001260"
     CDS             complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="NOB43_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCI0982130.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="NOB43_001261"
     CDS             complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="NOB43_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HCI0982131.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSREESSSSTSSSA
                     STSESSK"
     gene            complement(29103..29843)
                     /locus_tag="NOB43_001262"
     CDS             complement(29103..29843)
                     /locus_tag="NOB43_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HCI0982132.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="NOB43_001263"
     CDS             complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="NOB43_001263"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCI0982133.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31214..32152)
                     /locus_tag="NOB43_001264"
     CDS             complement(31214..32152)
                     /locus_tag="NOB43_001264"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCI0982134.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32145..32636)
                     /gene="def"
                     /locus_tag="NOB43_001265"
     CDS             complement(32145..32636)
                     /gene="def"
                     /locus_tag="NOB43_001265"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI0982135.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32651..35059)
                     /gene="priA"
                     /locus_tag="NOB43_001266"
     CDS             complement(32651..35059)
                     /gene="priA"
                     /locus_tag="NOB43_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCI0982136.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35312..35617)
                     /locus_tag="NOB43_001267"
     CDS             complement(35312..35617)
                     /locus_tag="NOB43_001267"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0982137.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="NOB43_001268"
     CDS             complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="NOB43_001268"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCI0982138.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9885 a         7990 c         6705 g        11987 t
ORIGIN      
        1 attccttaga cagcttttat tcgattatct cattgttggg aatagcaaaa catcccgaat
       61 tgattgtgca tcagttagca acattactaa tctgtcgatc ccgatgccta gaccaccagt
      121 tggcggcata ccgtattcta aggcttccaa gaagtcttcg tctacaccgt gagcttcgtc
      181 atttcctagt tcacgttctt tttcttgcgc ttcgaatctt tctctttgat caattggatc
      241 gttcagttct gtaaaggcat tagcaaattc gcgccccact atgaatagtt cgaatcgatc
      301 tgtgaatcga ggatcttctg gatttttctt cgctaaaggc gaaacttcga ctggatgtcc
      361 gtatacaaac gtcggttgtg tcaatgtttc ttcaacaaat gtttcaaaga attcattgat
      421 aacatgtccg acacccatag cttcggttac ttctacattg tgtttttcgg ctaaagctaa
      481 tgcttcttcc aatgtcattt cttgccagaa gtctacacca gtttgttctt tgattgcatc
      541 taccatatgg atgcgtttaa agtcactttc taagtcgaca gcttgtccat catatgtgat
      601 ttttgctgtt cctagtactt tttcagctgc gttacggata ataccttctg tcagattcat
      661 tacatcattg aaatcagtat atgctgtgta tgcttctaac atcgtaaatt ctggattatg
      721 tgtagtatca attccttcat tacggaaaac gcggccgatt tcataaactt tttccattcc
      781 gccaacaatt agtcgtttta aatgaagttc tagcgcaata cgcaaatata aatcaatgtc
      841 cagtgcatta tgatgcgtga taaatgggcg tgcggcagct ccacctgcct cattgtgcaa
      901 tactggtgtt tctacttcaa tatagccatt gccatctaaa tagcgacgga tttcgctgat
      961 aatttggctt cgtttcataa atcggtcaaa gctttcgcga ttactgatta aatccaagta
     1021 gcgttgtctg tagcgttgtt caatattcgt taagccatgg tatttatctg gcagtggacg
     1081 aagtgctttt gacaaaatcg tgatttctga agctttgata gaaacttcgc ctgtgtctgt
     1141 tttcatgatt tgtccagtta caccaaagaa atctccaagg tctgcatgtt tgaatacttc
     1201 ataggcctca tcacctactt ggtcttttct tacataaatt tgaatttggc cttcacgatc
     1261 ttgtagatgc gcaaatccag ttttcccttt tcctcggcga gtcatcatac gaccagctac
     1321 actagcggtc aatcccattt ctgctagttc ttcttttgtt cttggatcaa atagttcatg
     1381 caattcttct gagttgtgcg tgcgttcaaa tcgttttcca aatggatcga ttccatcttc
     1441 acgcaattgt tccatttttt gacgacgtac aagcatttga tcatttaaat cttctacttg
     1501 atgttgttgt tcctgtgtca caaaagttcc tccattctca tgttaatctc tttcctataa
     1561 tgccaatgaa acacaaaaaa agcaagccga acttggaatt tcggcttgaa aattcacgaa
     1621 aaacttagaa atcacaacgt ttgtttcaat agtacttttt ccgctttttc tacaaattga
     1681 tccagcaggt cattgatttc ttgctgtttt tctgtctgat tgattgctac tttcactttc
     1741 gctgctcgag gaatcccttt taaataataa gccgcatgtg ttctgaattc tctacaagct
     1801 actttttctc ctttgagatc tgctaagcgt tgtaaatgaa gtttagctgt agcaattttt
     1861 tcggctggtg ttggttcagg aatcagttct cctgtttcga gataatgctg tgtgcggtga
     1921 atcatccatg gattgcccag cgctgcacga ccaatcatca caccgtctgc accgacatag
     1981 tcaagcatcc attttgcatc ttctggcgtt ttgacatccc cgttccccat aaatgggatc
     2041 gtcaaatgtt ttttcacttc tttcaatact tcccagtccg cttttccttc atacatctga
     2101 acccgtgtac gtccatgcat agcgatggca cttgctccag ctgattgtgc tgctaatgca
     2161 ttttctacag caaagacgtg ctcttcatcc caaccaatac gcatcttgat tgttactggg
     2221 atatttactg ctgaagaaac agcttggacc atttcgtata ctttctcagg atctaaaagc
     2281 cattttgctc ctgcttctgc tttgattact ttatttactg gacagcccat attgatatct
     2341 attatatcgg cagctgtgtt ttcttcgaca aattgagcag cttcaactag actatcttta
     2401 tttccgccaa atatctgtaa acttaatgga tgttctgttt cttcaatgtg gagcatctct
     2461 aaagtttttt tgtttctgaa atgaatacct tggtcactga tcatttcaca tacgactaag
     2521 cccgcaccaa attctttgac agtgactcga aatgctgaat ttgttattcc agccatcggt
     2581 gcaacaacga cacgattagg gatttccaca ttgccaattt tccatgtgtg ttccacttaa
     2641 atccctccta aggcttcttt cttcaatcca tctaattctt cttcgctata cttgtatttg
     2701 ttattacaga aagaacaaac cgcttctgca ccgtgatctt cgtctatcat tgcttggatt
     2761 tcttctgcac ctaacgcgat aattgcttct gcaaattttt cttttgaaca gtcacatttg
     2821 aattgaacag gcattttttc caaaatgttc aattcttctg taccaagcaa tcctttcaat
     2881 atttcttctg gtgtctgtcc ttcatctaag agggtagaga ttcttggtgt cgtttttaat
     2941 tgttcttcga tcttgctgat tgtttcttca tcggcacctg gcatgatttg gatcatgaat
     3001 cctcccgccg tcttgatgct gtcgtcagta ttgaccaata cactcagtcc aacagctgaa
     3061 gggatttgtt ctgagatagc aagatagtaa gtaaaatctt cagcgatttc tccagaaaca
     3121 atcggcgttt gcccagaaaa aggttctttt aatcctaagt cttttgtgac agtaaacatt
     3181 ccttgtgttc caactgctcc ccgcacatcg attttacctt cactatttag aggaagactg
     3241 agatgcggat ttttgatgta acctttcaca tctccctttc catttgcatc tactacaatt
     3301 cctgttgctg gaccatcgcc ttggattcga acagttagtt tgtcttctcc tttgagcgtc
     3361 gcaccaagta gcagactacc gaccaatgtc cgtcccaaag cagctgagga ggtgtgccaa
     3421 gtatcatgac gtctttgtgc ctccgctacg gtatttgttg cttgaacggc gtatgctcgg
     3481 acgaatccgt cgtgagcaag tgccttaacc aaataatctt tcatttgtta tgtactcctt
     3541 tttccgtttt taaactcata gtgaatcata ctagcaacta ctgctttttt caactttgga
     3601 atgcttcttt taaaaataat tcagaatcat ctagaaaaca ggacatcacc ctatttacaa
     3661 cttaaataaa gaaatctccc gaaaaccggt ttttgttccg gttttcggga gtcatatcag
     3721 atcaattgac ctatattttt ttatttgtat tgatcgtctg aatgattatc ttctgattgt
     3781 tgagaatctg aatcatgttc tgctttattt tcctcattca gttcatgttt tgcttcttca
     3841 aaatcacgtt tttcttccgc ttgtttttca gcgtcttttt cttccaaagc acgttttgct
     3901 tcttcaaaag ttttcgcttc tttttcgctt ggataatcat ttgactcagt accttcaggc
     3961 atcacaccgt gttcaaacaa tgacttgatt gctttggcat ccaatgtttc gaattccaaa
     4021 agtttttcag caatcagttt atgctgtgca cgatgagctt cgatgatttc tcgagcttta
     4081 tcatgagctt ccatcaagat ttttcgtact tcttgatcaa tctcgaaagc gacttgttcc
     4141 gagtaagctt ttgtttgacc atagtcgcgg ccaacaaaca cttgatggtt tccttcatat
     4201 tgaacaggac ctaaacgatc actcattcca tattctgtta ccatgcttcg tgctagagct
     4261 gtcgcttgct caaagtcatt ggaagcacca gttgattgga cattgaagat gatttcttca
     4321 gctgtacgtc caccaagtaa gcctacgatt tgttcaaaca tatcttcttt cgtcatcaag
     4381 aactgatctt cttttggtaa agcgatcata tatccgccgg cgcgtccgcg agggatgatc
     4441 gttactttgt ggacgacccg agcgcgactc aatactaatc cgacaatcgt atgaccagct
     4501 tcgtgataag caaccatttc gcgttctttt ttgctgatta cgcgatcttt tttagctgga
     4561 cctgcaatca cgcgatcttc cgcttcatcg atatcagaag catcgatttt ctttttattt
     4621 cttctagcag ctactaacgc tgcttcattc aagacatttt ctaaatctgc tccggcaaaa
     4681 cctggtgtct gttgagccac aactttcaag tcaacgtcat ctgccatcgg tttattccgt
     4741 gcatggactc gcaagattgc ttcacgacct tttacatctg gacgtccaac taaaatctgg
     4801 cggtcaaaac ggcctggacg tagtaacgct gggtctagta catcagaacg gttggttgca
     4861 gcaatgacga ttactccttc atttccgtcg aagccatcca tttctacaag caattggttc
     4921 aatgtttgtt cgcgttcatc atgtccgccg cccataccgg caccacgttg acgacctacc
     4981 gcatcaattt catcaatgaa aatgatagct ggtgcgtttt tcttcgctgt ttcaaacaaa
     5041 tcacgaacac gacttgctcc aacaccgaca aacatttcta cgaaatcaga acccgagatc
     5101 gagtaaaacg gtactccagc ttctccggca acagcttttg ctaataaggt tttacctgtt
     5161 cctggaggtc cttctaaaag tacacctgcc gggatacggg cacctaattc aacaaatcgg
     5221 cgaggatctt tcagaaattc aacaacttca actagttctt gtttttcttc ttccgcaccc
     5281 gctacatcag aaaaacgtac gcgattagct tttttgtctg cttctttggc ttttgattta
     5341 ccaaagttca tgacacggcc gccaccgcca ccgccgccgc cttgttgtcc catcatcatg
     5401 taaaagaaaa agatgatgat tacgattggc aagaagctaa gcaataggga aacccatata
     5461 ccgctgcttg attcttcttt tactgttgta gcaactttgt tttcttttgc cagttctgtt
     5521 acttggctca atgttgtatc atttggcaaa atgattgttg tgaaatgggt agtagtcgta
     5581 tctgttgaac ctaagatagc taacccaccg ctgttagcga cggtctgctg ttctttgtat
     5641 tcaccagtga tcttatatac accatttgca ggctgcactt caaattcttt gatcttgcct
     5701 gcttgtagtt gttctgtgaa ttttgagtac tcgatatctg acgatcgctg gccgttatta
     5761 ccaaaaatga aataaacgac cattaccatc gctaagatta cgaggacata atacaaggca
     5821 tttttcatca tgccgttgtt ctttttgttc atagttgccc tccctaagcg tcaatttaat
     5881 ttaacagttt tttatcaatc ctgaccattc tattgtacca taatttaatt gagatacagc
     5941 attaatttga ttgataaaca ctaggtttca atacaccgat gtacggaagg ttacgatatg
     6001 cttctgcata atccaagcca taaccgacca caaattcatt tggtacgttg aagccaacat
     6061 aatctgcttc gatatttact actcttcctt caggtttgtc aagtagtgta acaattttga
     6121 ctgattttgc tttgcggtat ttgaaaagat ccactaaata agcaagtgtt cttccgctgt
     6181 caatgatatc ttcaacgatc aacagatcgc gaccttctac attcgtatct aagtctttga
     6241 cgatttttac ttcccctgac gagactgttg cattcccgta gcttgaaaca tccatgaaat
     6301 ccaattccaa atacgtatcg atagaacgaa cgatatctgc catgaatggt accgctcctt
     6361 ttaagacacc tactactagg ggattggtgt tttggtaaat ttctgttaac tctttgccta
     6421 gttctttgca acgaacttgt atctcttctt gtgagatcaa aattctctca atatcctttt
     6481 ccaacatcag gttctccttc caattgcttc tttttgatat ttgtaaagaa gtatgtagtg
     6541 tattttatca gtttcttcac gaatactcaa atatgaaaag gcaaaaggta tcaagctata
     6601 tatatttctt ttggcatctg taatgatcca agcatgctgc ctttgtgaat taggtacttt
     6661 ctgatcgata aaatatctag atactttttt tgtgagattc tctgttaatt taatgcggtc
     6721 tcctgctttt cttttttcga catacagttg cacatcagca ggaatccaaa tgtcatgaga
     6781 aaatagagac catgaatctg ttgctttgat gtcccctgca ttttcaggtt tgaccagacc
     6841 aatccattct gtttcattca aatatattcc ttgttctgga atcagcaaca agcgctggtc
     6901 ttctgtctgg ctagttgctt gtttttcttt tttagagagt acaacaaaat gatactctct
     6961 tttcagtatc caattattgc caatactgag ttgccattgg ctttttttct gttgccactg
     7021 gtctaaaatc gactccattt gttgttcttt caaaataatt cctgtttttg agaatgcttt
     7081 gtcgaaaaag gagtaaaaaa aatagtatcg ttcagcatct gtcatttctt caatcatttc
     7141 tgcagaaaat cgaaattgtt cctcccactg ttcgacttcc ttttcgatca actgtcccat
     7201 atatttttga atgacttggt ctgcccattg gatctgttgc gaaaattgct ggaaatgtct
     7261 caacgcctgt gtattttctt gtttcaattg aggaactacc aaatgacgaa gccgatttct
     7321 ctggatatct aacaattggt ttgtctgatc ctcaaagtaa acaagctgcg attccgctgc
     7381 ataagtatat aggtcttctt tgctaaaact cagcaacgga cgaatcagtc tgcccgtagc
     7441 aaatggttgt acttctttga ttccagaaaa agtatttaac tgtcccccac gaacgatttt
     7501 cattaacacc gtctcgattt gatcatctcc gtgatgagca gtcatcaacg tgtcatattg
     7561 tccttcttcc atcacgcgag tgaattcttg ataacgaaag ttacgagctt ctgtttctat
     7621 ggcggatttg gctggatctt cccaaatact tacatataaa gggagattct tctcttcaca
     7681 atatgagcga agataggcag cttcttctgc tgattcttct cttaattggt gattgatgtg
     7741 gacgatacct aaagaaaaac cgatttggcg ttgcacttgt aaaagtaaat ggagcaaaac
     7801 catcgaatca acaccacctg ataccgctgc taaaattctc gatccttgtt gccagaatcc
     7861 ttgttcattc ccgtgccgaa taaatgactg ctgtaatagc ggtgcttttt tcccgccttt
     7921 ttcaacgttc atcctttcca caccctttct tcctaaaaaa aagagagcgg gaaaacgtct
     7981 aaaacgacaa ttaacctgcc ctctgttgat actatgaccc aaatagtcgc actatcatta
     8041 tttgcggctt tttagctgcg acgtccgcca cggccaccgc gctttccttc tgtgtttcgc
     8101 ttcaatgaag ataagcggtc atcgctatct ttcaaaaatg aactcatcaa tgaatcgaag
     8161 tcttcttttt gagctgaagg ttgactgcga gaaaaagatt ttttctgtgc tggacgattt
     8221 cggttgtcac ggggatcttt ttgttgatat tttttaggac ggctttcttc tccagattca
     8281 gcaggttgtt cctgcgcttt ccggatagat agtccgattt ttccatcatc atttactgaa
     8341 ataactttaa ctgttacttc atctcctaca cttaaaacat catggatgtc ttttacatag
     8401 ccatttgaca cttcgctaat atgaactaga cccgtttttc cagcacctag atcaataaac
     8461 gcaccaaaat ttgtgattcc tgatactttt ccttgcagtt ttgctcctac ctcgattgac
     8521 ataaaaaaaa tgttcctcct aattatttcc cttttttata ttcctgctta ttttgcagtt
     8581 gtagaactag ttgattgatc tgtttcattt gtcgagctgt ctgtatttga ttctaatata
     8641 ggataaactt tttcaccgtc ttttgagtaa aagaatttgc ttctggcaag tttagctaca
     8701 tactcatcat ctttcagcaa tgaaacatct tggtgcagct gatcaacgtc tgcgttgact
     8761 tctttcattt cagtatttgc ttcgactctc aattcgttca attgatgcat cctttgcatg
     8821 tcatggaaaa tctgcacacc tattatcgcg aaaatgacca aagcaccaac aaaaattgca
     8881 gccagtctgc gtcttcgaaa aatcagttga cgttgttgtt gctgaaattc agcatacttt
     8941 ttctttgcat attccgtatc tagcgcagcg attttattgc tttttttcgt cacttggatt
     9001 cgctccaatc tttttgattg tctttttcat tataccaata tcgtgaaagc ttgtctaatc
     9061 tatttctcta gtgtttctgt gcgattttca gaaataattt cgtacatttt ttgtgcatct
     9121 tcttttttgg ttgattcatg taattccgta attttcactt ccaacgtttt gttgccaaac
     9181 tggactttca aaatatcgcc tactttgaca tcactggaag atttcgccaa tttaccgttg
     9241 atttgaattc ttcctttatc agctacttct tttgctactg atcgtctttt gatgattcgg
     9301 gaaattttta aaaatttatc taatcgcata tcttattcct cactttttaa tttttttatt
     9361 taatcgcagg attttcttac caaaaggcaa cattagccat tctcgtactg taaacagacg
     9421 aagacgaatc actgcataaa tgaacacaga agccccgatc ccaactccta tcacgctgac
     9481 aaaaaaagca gtggaacgat gagttacagg accaaatact atattcaata caccataata
     9541 cagcagcagt actactgtca tacaaagaag gctgaacatc aacttccgtc caaaatgccg
     9601 ttctttccaa aaagcattta gctcttttgt ttcaattcga acaaaatacc aaagcgtcac
     9661 acctaatcct aaaagggtag acaggcttgc acctgctgtt cctaataaac cggtcagaaa
     9721 agaagtagtc aatcctttta ccaatagtcc ccatcctgcg ccttttaaag aagggcgaaa
     9781 cgagttcttg ctttgagcaa tactttgata agcttggatg actgcagtga aagcaatgga
     9841 aaaaacaaat aatacaagcg ctgcatttcc cgcataatct ttaaacaacg cataattgat
     9901 ataagggagc agcaaggcta atcccaaaga cgcagctaat gctaaagcgg tcgtcaatct
     9961 aagatagatt ttggctgtct gtaaaaactg acgatagatc cggttggtca aatgacgagt
    10021 caacgcaggc aggaatgtcg cacttaatgc agtggcaatc actaaaccta attgtactaa
    10081 aggctgacct cgatcataga ccccttttgc tatcttcgca ccgtattctg acagtccgta
    10141 aacttccaaa gcatttttta caaagaaaga gtcgatcagc tggaaaaaga taagcaatcc
    10201 actataaatc gaaaccagtc cgccttctac cagaaaacgc cggatcaagg gctttgacgg
    10261 ctgtttgaac aatggaaacc gtcggaagct taacgctcct ccatgaatct tttgttcata
    10321 gtagtgaagg atcccatatg cgcataaacc gccaaaaaca gctccactca ttgctgccgt
    10381 ccctgtttgg tacaccgtcc atccaagctt tctaaaagca aacgcactac agacaatcac
    10441 aaaaacacga acgaactgct caactacttg agaaacagca gttggttcca tcaagaatct
    10501 tccttggaaa ttccctcgat aaaaagatag accaggcatc agcaaaaagg taaaggaaac
    10561 tacttggatc agcggtttca attgtatgtc tcccatcatc caagcaatcc agctgctaaa
    10621 tgcaaagaca aacaaccaca aaaagacacc tgtccaaaat actaagggat aaagattttg
    10681 caaagcttgc tttcgctcga aaggattctt tctttctgca acgtactttg atatgaactg
    10741 cggaagaccg gataaagcta aagtcattgc tatcccataa attggataaa cttgctgata
    10801 aacataaaaa ccttcgtcgc ctactaagtt ttggagggga attcggtaaa gggcacttaa
    10861 tacttttgct atgaaagaag caatcgtcaa tacaaatgct ccttgcatga cgcgccgcat
    10921 ttctttatga tccaaatcat tgctccttcc tacgctgaca gatatttttg ctcacgcaac
    10981 gctttgacaa acttttggat ttcctgaagc catactgctt cttccatttg gttggggatc
    11041 gtcaagcgta tcaccatctg ttctttttca acgcctagac tggcttttag ttttgtcgct
    11101 gtcagtgctt cgaataactg ttccacacta tagcgttttg ttccaacttt acttagagta
    11161 aagactatat gcgcctcctg tttccttatc gtttctagga gcgctcgatc gccatccatt
    11221 ttgatctgcc caattgtcaa gagatgtgct acttcttctg gatattctcc aaaacggtcg
    11281 agcagatcat cttctagttc atctagcatt tcttgcgaat caagttcacg aattcgttta
    11341 tagatctcga ttttctgccg ttgatctgcc acgtatgttt caggtagata cgcatcgaca
    11401 ccgaggtcga tctcaacagt ggtcttctcc acttgactat tctttccttg tttacgagaa
    11461 acagcttcgc ttagcatttg agaatacata tcgaaaccga ctgcatcaat aaatccatgc
    11521 tgctgagcac ctaagagatt acctgcaccg cgaatggaaa gatcccgcat cgcaatcttg
    11581 aatccagatc ccagttctgt aaaatctttg attgcctgaa gacgtttttc actgacttcg
    11641 ttaaggatct tctgctgctc atacataaag taagcatatg cgacacggct gcttcttcct
    11701 acccgccctc gcaattggta taacgtggat aatcccatat aatcagcgtt ctcaacgaac
    11761 aacgtatttg cgttcgggat atctactcct gtttcaatga tggttgtagt gacaagaaca
    11821 tcatattgac cttcaataaa ttcaaaaagc gtattttcta attgcgcctc tgtcatttgc
    11881 ccatgagcat aaccgatccg tgcttccgga acgagttctt ggatttcttc tactttttgt
    11941 tcgatcgttt ctacccgatt atataaatag aatacttgtc cacctcgtcc catttctcga
    12001 tggattgctt cgcgaatagc cccaggattt ttttccataa catacgtttg gatcggataa
    12061 cgattcgcag gcggtgtttc gattactgaa agatcccgca cgcctaacat cgacatatgc
    12121 aaagttctcg gaatcggtgt tgcagtcaga gtcaaaacat ccacttgtgc acgtaactgt
    12181 ttcaatcgtt ccttatgttt tacaccaaaa cgttgttctt cgtcaatgat cagtagaccc
    12241 aaatcgctaa attcaatatc ttttgacaaa attcggtggg ttcctacaac aatatcaact
    12301 tgacctgtac gcagttgttc gatggtttct ttttgttgct ttcttgttct gaaacgactt
    12361 aatagcccga tatttacggg gaaaccttca aatctttcca gcatcgtttc atagtgctgc
    12421 tgtgccaaga tcgttgttgg aactaaaaag gctacttgtt tgctttcctt tatcgcttta
    12481 aaggccgctc gaagcgctac ttctgttttc ccataaccaa catcacctac gagtagtcga
    12541 tccattggtt tttctttttc catatcccgt ttgatctccg ctgcacttct caactggtca
    12601 tcagtttcag agtaggggaa ggcattttcg aattcttttt ggtaggcgtc atcaggtcca
    12661 aaagcatatc ctttttctga ctctcttgcg gcatataatt tgattagatc gtcagcgata
    12721 tcctcgattt ttgaagagac ttttcgcttg gttttcgtcc attcacttcc gcctagctta
    12781 ttgatgcgag gcgctttggc ttcagaggcg acatattttt ggatcagatt cagttgagta
    12841 acaggaataa acagtttgtc gtcgttttga tacaaaatag tcatatagtc ttggtgaacg
    12901 ccatctactt ctagcgtttc catcccaatg tatttcccga taccatgatt ggcatggaca
    12961 acgtaatctc ctgcttttaa ctcattatag cttttcaatc gctctgcgtt tgttactgtt
    13021 tgacgtctcg tttgtttttt cgtcgttttt tggaaaattt ctttttctgt gatagctact
    13081 attttttctt gaggaagttc aaaaccagcc tgcaaagctc cttcaactaa ttgtacctgt
    13141 cctctgatca atgcattttt ttctgtttct actactaata tgtcttcatc tcgaagcatt
    13201 tgttctgctt tgcgtattct gtcctttgtc ggaataaaga tcacaacagt ctgtttttgc
    13261 ttgcgccaac ggtccatttc tgttttcagc aatggcattt gtccgaagaa ctgttgcatc
    13321 gtccgatatt gaaaattatg gattgcttgg aaacgaagat ttcccatccc tttttggaag
    13381 agtgagaaaa aggttgtggt gaacttttcc ttctgcacga ttttttgtat atctgctgaa
    13441 aatgtctgct cagaaaacac ccgcaattcg ctgatttttt gagtctgcca ttctgccgct
    13501 tccctttcga tttcccgatt tgtttccatg attcgctgat aatcatcaac gactagtaaa
    13561 ctatttgaag ggaaataatc caagatcgtc acagattctt ggtaaagaag atctgagtag
    13621 aattttgctt cttctgtcgg gacacctgct tgccagcttg aagtcagctg accgaagtaa
    13681 tcttgcaaaa actcgcggtc tgcttcttct gtggtcgcag caagccgttt ttctagcatt
    13741 ttttgcattt gctctattcc atgttctaga tcctctggtc cgtagacttg ttcactcgtt
    13801 ggggaaaccc agatttcttc cgttttttcg attgagcgtt gtgtttctgc ttcaaaatac
    13861 cgcatagaat ctatctctac atcaaatagt tctacacgaa caggataggt tgtcgttaac
    13921 gggtaaatat cgataatgct tcctcgaata ctgaattctc ccggttttgc gaccatctct
    13981 tctcgtacat agcccatcaa agtcaattgg cgaggaagat tttccacgtc tatctcatca
    14041 ccaatatgcc aattcaattg cgcctgtagc caagttttct tattcggcag tcgtttgtgc
    14101 aaagatgcga ctggcaacaa atagatacct gctttttttt cttgaagtgc gttaagcgtt
    14161 gcaactctct cgcctcgcgc ttctggagaa gaaaaggcca tttcagcaga aagcacttca
    14221 tccactggaa ataaatggat ctgatcttgc ggaatcacat gttgcagatc ttctgctaac
    14281 tgattcgcat aatacaaatt tggcatcaga ataatcatgt ttttatttgt tttcttaaac
    14341 gctcgagcaa atagaagtgt tttcgctgag cccgctaatc ctgtgattag ttgtctaggc
    14401 attttttctt ctaaattgct gacccattct tttacttgcg gatcttttcc gactaattga
    14461 ataatatcca ttccttttcc tccttcctca attgaatcga ttcatcgcat ccacgaacga
    14521 atgcccttct atgagatatt cgactgcttt aacagattga cacatgcttt cttctatcaa
    14581 aggctgattt tctttgctga aaggactaag cacatgctgg actactgttt ttttcccttc
    14641 tggcctgccg attcccacct tgattcgatc aaagacattc gtattcaaat gggaaataat
    14701 acttttgata ccgttatgcc cgccggcact tcccttttga cggagccgga tttttcccac
    14761 tgccagatcc aaatcatcgt agattacgac taattcctct ggataaatcc caaaataagt
    14821 cattagtggg ccgactgcac gaccagattc attcatgaat gtttgtggtt tgactaaaag
    14881 gatcttttct ccattatgaa aaaattcggc aacttctgct tcgaacggat tttttttgaa
    14941 agtagcttga tgctcgcgtg caattttatc cacgaccata aagccgatat tgtgttttgt
    15001 atattggtat ttggtacctg ggtttcctaa cccgacgatc attttcattt ttgttttcca
    15061 cctaattcta aaaagcagca caaaaggctg gactgctaat tagcggtcca gtccatcgag
    15121 cttttttctt ttttatactt gtcaatgcat agtataacac aaaacaaggc gtttcggcta
    15181 aaagagaatc gttaataaat gataaagaaa ttaaaaattt cttcaaagtt taatgaaata
    15241 attgatatat aaaaatagtg aaataacgca catgtaagct tttacatata atacaacctt
    15301 gttatctgtt atattttata gccaaatagc gtgacatggg gcttgagaaa tgttagcata
    15361 agcatgggaa aaaacaaatc aatggaagga ttgatactaa atgactgcag ctgcagaaaa
    15421 aaaagatcat caaaaagtta ttcttgttgg agacggcgcc gtaggttcta gctatgcctt
    15481 tgctctagtt actcaaaata tcgctcaaga agtaggtatt gtggatatca atactgctaa
    15541 aactgaagga gacgcaattg acttgtctca cgctttggca tttacttcac ctaaaaaaat
    15601 ctattctgct acttacgcag acgcacatga tgctgactta gttgttatta cagctggcgc
    15661 accacaaaaa ccaggtgaaa ctcgtttaga cttagtaaac aaaaacctaa aaatcaaccg
    15721 cgatgttgtc acacaaatcg ttgaatcagg atttaacggt atctttttag ttgccgctaa
    15781 cccagtagat attttgactt actcaacttg gaaattctca ggtttcccta aagaacgcgt
    15841 aatcggttca ggtacctctc ttgactcagc tcgtttccgt caagcacttg cggaattagt
    15901 tgacgttgat gcacgtaacg tccatgctta catcttaggt gaacacggag attcagaatt
    15961 cccagtttgg tcacatgcaa atgttgccgg cttgcaaatc tatgaatggg taaaaaacaa
    16021 cccagaaatc gatgaagaag ctatggttaa cctattcttt ggcgtacgtg acgctgctta
    16081 cacaattatc gagaaaaaag gcgctacttt ctatggtatc gcagtagcat tagcacgtat
    16141 cactcgtgcc atcttagatg atgaaaatgc tgttcttcct ttatcagtat tcatgaatgg
    16201 cgaatatgga ttgaacgaca tctacattgg tgcacctgct gttatcaacc gtcaaggtat
    16261 ccaaaaagta atcgaaattc ctttaagtga cagcgagcaa gaccgtatgg ctgcttctgc
    16321 taagcaatta aaagaaattc tagatgaagc ttttgctaaa ctagacgctg aataatcttt
    16381 gaacatgacg gaaaacatct attcggtgtt ttccgttttt ttattttatc acccttatgg
    16441 tttctaaatt ttttcataaa gtagagataa ccttcgtctt ttcctctaaa ttatgctatc
    16501 atgagaccgt tccaccctaa acttttactt aaggagttgt cgatatgaca agatcttcgc
    16561 atcgaaaaaa atcgaaacat gttgctttgc tttcagttct tggtgttctc ttagtgctga
    16621 tcagctttta tacctatcgc agtacatact acacaaagca ttttttgccg aatacagaaa
    16681 taaatggaat aaatgtcagc aatctaacag tcgaaaaagc aaatgaaaaa ttaaaagaag
    16741 cttattctga taaaaaactg gctattaaag aagatggaaa agtctggcag gaagtaccaa
    16801 aatccgagct cggctacaaa gatgatttca cttcggagct ttctccgatc ctaaatgaac
    16861 aaaacggatg gacttgggga atgacttatg tctcagcggc agaaaaacaa gaaatagatc
    16921 ctgtcagtca aaaccaccaa aaactagaca ctaccgttca gacattgaca actaagctga
    16981 ctgatttgaa caaagaccgg acacctacta ctgatgcaac gatcgaaaaa gcaggtgact
    17041 ctttcgttat caagcctgaa gtcaatggaa atacgatcga cgtcgatgct gcggtcaaac
    17101 aattaaaaag tgcggtaaac tctggtaaag atacaattga attgactgaa ttcaaagaaa
    17161 aaccaaaagt aacatctgaa gacagctcac tgaaagaaca actcgcatcc atgaatgcta
    17221 tcgcaaatgt aaaagctact tacagtataa acggtgagac tttccagatc ccatcaagtg
    17281 atattatgag ttggctgacc tacaatgatg gaaaagtcga tttagataca gaacaagtac
    17341 gtcaatatgt aacagattta ggcacaaagt ataacacaag tacgaatgac acaaaattta
    17401 aaagtacaaa aagaggagaa gttacggtcc cagttggcac ttacagttgg acgatccaaa
    17461 cagacagtga gacagaagca ttgaaaaaag cgattctggc aggccaagat tttactcgtt
    17521 cacccattgt gcaaggtggc acaaccgctg atcatccatt gatcgaagat acgtatatcg
    17581 aagttgatct ggagaaccag catatgtggt attacaaaga cggaaaagtg gcccttgaaa
    17641 cagatatcgt ttccggaaag ccaactacac ctacacctgc tggagtcttc tatgtttgga
    17701 ataaagaaga agatgcaact ttaaaaggaa caaatgacga tggaacacct tacgagagtc
    17761 cggtaaacta ctggatgccg attgactgga caggtgttgg tatccacgat tcagactggc
    17821 aacctgaata cggtggagac ttatggaaaa cccgcggttc acacggctgc atcaacaccc
    17881 caccaagtgt aatgaaggaa ttattcggga tggtcgaaaa aggaacgcct gtattggtct
    17941 tctaacaaaa ataatatata aaaagaaagc acccgtacga ttggtacagg tgctttcttt
    18001 ttattatcta acaatgtgct acttacattt cagcagcagt aaagacttct gaaacatcat
    18061 catcgtcttc tagcttatct actagacgtt ccaattgctc tttttgttcc tcatttaaat
    18121 caatcgtcgt ttgtggaatc atcgtcaatt ctgcttgcgc caaagtgaac tctttttcca
    18181 actcatctcg tacagcagca aaatcttctg gtgcagtata aatctcgaat acttcaggag
    18241 aagtttgcag atcttctgcc cccgcctcta atacatcctc aaacatcgtc tcttcatcaa
    18301 cagtcaaccc atcgcgttca atagcgatat atcctttgcg gtcaaacaag taactgactg
    18361 aacccgtttc tcccagtgat ccaccgtttc gagtaaaagc tactcggaca tttgtcgctg
    18421 tccgattacg gttatctgtc aatgcatgga ctaagattcc tactccaccc ggaccatatc
    18481 cttcatacgt gatttcatcg taattcgttt catctacggc actcgtagcc tttttaatcg
    18541 cccgttccac attgtcgtta ggcatatttg cagcttttgc tttgtccaca acaagccgca
    18601 aagctggatt catagatgga tcaggaccgc ctgctttagc tgccatataa atttcacgag
    18661 aaagtttctg aaagactttc cctcgttttg catcttgggc attttttctt ccttggatat
    18721 tatgccattt actatgtcct gacatgattt ttcctccctt gttcttttga gaatacactt
    18781 ctattctagt actatttcac aaaaaaacaa agccacagcc aatctataaa cgcttcttga
    18841 atgccgcaaa aagcacacat aatatcacag cagtcagagc accgatcgaa tccaacatga
    18901 catcttggaa cataggtgtt cgtccaccgg tcatcatctg atggaattcg tccaaacctg
    18961 cgtaccctgt tgctgaaagc caagcaagga tcgctgtcag ccaccaaatt tttagcttgg
    19021 ggaaaacacc taaaaacaag ctgcctccca aaataaaata ggtaccgaaa tgtgcgccct
    19081 tccttaaaaa gaactctaaa aatttggcgt agcccagatg gtcgatactc accatacttc
    19141 caccataatt aaaacgtata cccgctaatg tgtctttaaa tggctgatta ggcagccagc
    19201 tttctaatcg cgaaacttgt gattgctgtc cgtaagtttg agaagaactg taaaataaga
    19261 ttataacgac tatcagtgcg attactaaat aaatatttcc gtttttcatt tgtttttttg
    19321 aagaattcat aagtcacctc tgtattttat cttagacttt ttttgaagaa acaacaatca
    19381 ttttcataga gacttcttcc ataaaaaagt gctatactta attttgtatt acaatatgaa
    19441 gggagttttt tcatgagtta ttcattaaat tggaatctag attctatttt ttccggaggc
    19501 agtcattctg atgctttgaa ccaacggatg aagcaattgg aagaccaaat gaacgagtat
    19561 tatcaccgcg taacaaaatg gtcacctagt tctgacaatg cagagcagtt aaacgctatt
    19621 cttcaattgc aagaaacgat tacgaatggt tttacccaat gcagcagcta tattactgca
    19681 ttgctttctg ccaatgtcaa tgattcagat gcaaaggtct tatcaggcaa gctttacgca
    19741 atgctgcctc gtctgcaatc agccgaaact gtattgtcaa agaaatttgc agaaatatct
    19801 gacaatgatt ggaatcagat gctttctcaa tcttcgtttg aaacaattgc ttttcgttta
    19861 aacgagattc gtcgtgatgg ctcacaatta ttatcagaag ctgaagaaaa cattataaat
    19921 acgctttctt tagatggtct aaatgcttgg agcagtcatt atgatacgat tgtagccagc
    19981 atttcgattc ccttcgaaca agatggacaa gtagtcgaat tatctgctgg acaagccttc
    20041 aataagatga tgggcgatcc agatccaaaa gtcagagaaa cacttttcgc agcatgggaa
    20101 gaagcctgga aagaaaaggc acccctcttc acggatactt tgaatcattt agatggtttt
    20161 agactttctg actatgaact tcatggtgtc acagattttc tacaaaaacc attagagtac
    20221 aatcggttga agaaagaaac attgtctgtc atgtgggata caatccagaa aaacaaacaa
    20281 ccccttgtta attacttgac tagaaaagct aatcttttcg gtaaagaaaa aatggaatgg
    20341 caagatcaag atgcacctat tattttaggc gatttgaaag aaaaaacctt tagttttgac
    20401 gaagcagcag catttattat cgaaaacttt aacaaattca gtccaaaaat ggctaaattt
    20461 gcccaatctg cttttgaaaa gagctggatc gaagcagaag atcgtcctgg gaaacgtcct
    20521 ggtggttatt gtactgagtt accagaaaca aaagaatcaa ggatctttat gacctacagt
    20581 aattctgtta atgaggttgc gacacttgct catgaactag gacatgcttt ccatagcagc
    20641 acgatgtggg atttaccttc tttaaatcgc gaatatgcca tgaatgtcgc agaaacagca
    20701 agtacattcg cagaactgat cgtagccgat gctacattaa aagtcgcaaa aacaaaagaa
    20761 gaaaaaatca atttgctaga tacaaaactg caaaatgctt tagctatgtt catgaatatc
    20821 cattcccgat tcatttttga aaatcgattc tatgaagcac ggcaagaagg attagtctca
    20881 gaagataaga tcacagagat gatggttgag gcgcaaaaag aaggctatca aggagcttta
    20941 gctacttacc atccatattt ctgggctgca aaattgcatt tctttattga tgacgtaccg
    21001 ttttataact tcccatacac atttggctac ctctttagtt tgggcatcta tgcttacgcc
    21061 aaccaaaagg gagcaaattt tgaagaagaa tatatccatt tactacgcga tactgcctca
    21121 atgacgacgg aagatcttgc gaagaaacat ttgaatgtcg atcttaccca accagatttt
    21181 tggcaagcag gtatcgacat ggtgactgaa gatatccaaa cgttcatgga attgacagaa
    21241 gaatttatct gatttctatt ttatcacaat aaaaaaagag ttagtccaga atgggctaac
    21301 tctttttgat taatcattct tacatgctga cagcaaagtc aggggcaaac cattgaactg
    21361 aaccaacttt tacgctttcg cctggttgag gagcatggat atattgtcct ccgcctaaag
    21421 caatcgctac gtggtaagtt ccgccttgtg acccccagaa taacaagtct ccagcttttg
    21481 cttgagaaac tgaaattttt gttccagctg attcttgagg aactgtccaa ccaccgatgt
    21541 cacgaccagt tacttgcatg taaacatagc gtgtgaaccc tgagcagtca aagccacttg
    21601 gatctttacc gccccaaaca tatggagtac caatatattt gtaagcttct gctacgattg
    21661 ctgcaccatt cacacttcca gaaggagctg gagcaggtgt tacaggtttt ggttgttcag
    21721 gtgttggtgt tggcgttgga gccggagtac tacttcctgt gccgtttcct gtatcaacac
    21781 tttgatctgt tgatggtgtt gtaggcgcag gtgttgttga ttcttctgtt gttgaagatt
    21841 caggcactgt tgttgattct tctgttgctg aagattcagg cactgttgtt gattcttctg
    21901 ttgctgaaga ttcaggcgct gttgttgatt cttctgttgc tgaagattca ggcgctgttg
    21961 attcttctgt tgaagattca ggtgttgttg attcttctgt tgctgaagat tgtgtagctg
    22021 atgatgattc ttcagtcatt gaagattgtg tagctgatga ttcttctgtt gctgagcttt
    22081 gtgcagtaga tgaagcttga gtagcttgtg cttcagcctc tgcttgttcg cgtgcttctt
    22141 tttcagcttt ttcttgtgca gcttgttgac gagcttgttc tgctagacgt tgttgttcac
    22201 gaatacgagc ttgctctgct tcagcttctg ctttttgacg gttcaagtca gctttcttgt
    22261 cttcagcagt tgcttgttca gcagctaatg aagttttcag tacgttcaaa tcagcttgtt
    22321 tagataaaag atcgcctttt tgagattcca aagcagcttg gttttcagct aattctttta
    22381 gtttagcatc gttttcagct tttttgtctt ctacagcttt tttatcttgt ttttgttgtt
    22441 ccatcaagtc gttgtttgct tttaccatcg ttgtcattgc ttgaacgcgt ccaatagcat
    22501 ctgctaatga atcagcattc aatacagcat cgatgtagtt tgagcttgtg ttgcttactt
    22561 gtgcttcgcg tgcttgtttt tggattgtat cttcacgttt ttcaatacgt tcttgtaaat
    22621 ctgcaatgtc ttttactaat tgtgcagatt cttgacgcaa tgtatcttgt tttgctaata
    22681 ggtcttgtgc ttgtgtgttg atttcagaaa cttggctttc taaggcatcg atttgtgatt
    22741 gtgcatctgc ttgttgattt ttcaagtctg caatcttttg atcttgctgt tgtatctgag
    22801 aatcaaaatc gtccgccgcg gcagcgatcg gtgatgctac ggcagtcaag gtcattgaac
    22861 ataccattac tgctgatatt aaactctttt tcactcttca ttcctccgac tggcttaatt
    22921 taataaatat ctaaatatat ttaagtcttt cttaacgata taaaaattgt accatagcag
    22981 tgtgtcaacg atataatagt tatgttacaa aaatgtttca aaacaacttt taaaaatgac
    23041 aaaactgttc gtttcagaaa atgatcatga aaaagccgcg ttaagtctag catttcttaa
    23101 gataacaacg attctttttc gctttcgacc taaaaataaa aaaagaaatt attcatcact
    23161 gaataatttc ttaaagggaa aaatgaataa tacaaatata atcatgttca acagcagtgt
    23221 aggtcctaaa aaccttgtaa taaaatacgt gttatttact actgctaatt taaaaatcaa
    23281 ctggaccacc atcgtaaaca attcataacc cgtgacaaag atgatcatac tgaaaaattc
    23341 agtaaagatg ttgacatgga taacgtcttt cattacatac atcaaccata caattaaagg
    23401 gagagctact gcatagatac cgataacgcc aatatagtaa gcgtcataga tagccccgag
    23461 aacaatcgtg gtaatcagta aataacgttt ttcaaacgcc atactgcaac ataataatgc
    23521 caatatcaga aagtgggcat ttgacatata ggtgcctttc gaccactccc ctagcattct
    23581 tgttaaatga ccatctatca acatcaaaaa gaacaaaacg attggcagat agtacttcat
    23641 tgtttctttc ttcaacatgg actaatcctc cgctagccgt tggacaatcg tcacaactga
    23701 cacgtcatac atttctgcat aaggtttcac ataaacttcc cgatccagcc cataactatc
    23761 tggtttcgtt ttaataaccg taccgatcgg caagttagct ggagaattcc ctccaagacc
    23821 ggatgtctgg acaacatccc cttctttgat atccgtatca ccagttaatt gggtcaccac
    23881 taaggcatgg agcttttcat catagttttt aagcaaacca aacgcttcgc cattagccga
    23941 agatacccgt actggaaaat gattggagct ttcattagag gatgacagta attcgatttt
    24001 agacgaagcc gtattgacct cgatcactcg gccaatcaat cctttttgcg acatgactgc
    24061 catatttgct tcgataccgt ctttagaacc cttgtctacg atcagcatgt cctgccaact
    24121 gtcaggcgaa cgagtaatga catttgccgt tactttttcg taactagtca gcgtctgatt
    24181 caactcaagt tcttttttca acgcttcgat ttctctctcg taattcttgt tttgctgtga
    24241 aacgtcatca tagctatcga ttttttcttt tagccgctca ttttcggcat aagttgaaaa
    24301 aagattatgg acagaatcta ctccatttcg tacccaccgt actggggcag agattgtttt
    24361 atcaaccatt gcaacactgt cattaacgat ggattggaag aaattgggct ttccttcatt
    24421 cgctcgctgc gcagcggtca cacttagtat cgtcaccacg atgataacaa taaccaaggt
    24481 aataataata tttttattag gattgaactt cttcacaaag acacctcgaa ttaattagac
    24541 tcttgtgttc aattttatca ctaaatgccg tgaaacaaaa ggtaagttgc tcctcttaag
    24601 ctttttttta gcaaataata gattctgtca tttttagcct gaaagacaaa tttttttatt
    24661 tgtttatgga tcaatctttg ctttgaataa ctgcaatcat accatctgaa aaagaaaatt
    24721 ctgcggtatc tgaaagaaat tcgttacttg cataagatgt cggatattct acttctttat
    24781 tttccaatac atacttgctg ccttttaatg taagattcga gacgggagtc aagcagcaat
    24841 aagctaaata cttcatatct ggtatctgtc ttactatatg ctctccaggc aaataataag
    24901 acaaataatt ttgacaatct ctgataataa gctgatgggc aaagggtttg aagcgaggtt
    24961 ccatacctaa ccagagattg gctaaaagat gatccaatct tccgcccgta gctccaatca
    25021 aagtgacttc cgcttgcggg taacgttcaa atgtttttaa gatacctaac tgtgtatctg
    25081 tatcgtcttt ttctgcaggg gaacgggtat actctttggc ttttgcaaat acttccttct
    25141 gctcttcgtt cgacaatgaa tcaaaatcgc ccactgccag atctactggg tagcctgctt
    25201 gaagcaggta cagcgcacca cggtctatcc cgacataggc atcgtatttg gacagcagag
    25261 actgcggcca gttttgcgga ttacctccag cagctaataa aattttcatt tagtctaatg
    25321 cctcttttaa tcgttcgatt tgtccgactg gattttcggc tccatagata tatgatcctg
    25381 caacgaagac atccgcccct gcatctttac agatttttgc tgtttctgga acgattccgc
    25441 catctacttc gattgcataa gtccaattgt tctctctacg tagatcagcg agttccgtaa
    25501 ttttttctac tgtttcttca ataaagcttt gtccgccgaa cccaggattg acagtcatga
    25561 ctagtacttg atcagccaaa ggcaaaacat gtttgatcat ggagactggt gttcctggat
    25621 tgataactac tccagcttta actcctaagc tttttgtcat ttgaagtgcc cgatgaatat
    25681 gaggagttgc ttcgacgtgg acagtaatga tatctgctcc agcttttgca aatgctggaa
    25741 tgtagttttc tggatcaacg atcatcagat ggacgtctaa cggtaattta gtaacaggac
    25801 ggattgcctg aacaatattt ggccctaatg tgatatttgg gacaaattgg ccatccatta
    25861 catctacgtg gatgtaatct gcgcctcctt tttccactaa ctcaatgtct ctttgtaaat
    25921 tggcaaaatc tgcactcaaa atggatggtg ctatcttcat tcttgtttcc tcctattttc
    25981 gtttaccttc tttttttgca tacattggtt ttcttttttc gatttcttgt aagaattgca
    26041 aataattgtc gtaacgtgtc tgtgcgatac cacctgtttc tactctatgt tttacttcgc
    26101 agccaggttc tttagcatgc atgcactctc taaatttgca atggacagaa gcttctacaa
    26161 attcaggaaa ttgtctcggc agttctcctg cttcaattgt caaaaagtca atcgagctaa
    26221 atcctggtgt atctgctact aacccgccat agataggaat cagttccaca tgacgtgttg
    26281 tatgccgtcc tcttccaagt gcatcagaaa tctctcctgt tgctaaattc agttccggtg
    26341 atatttgatt cagtagcgtc gattttcctg ctccagactg acccataaag accgatagcc
    26401 gttctgggaa gtaacggatc agttctgtcg tatcacccgt atgattgggt acaatcaccg
    26461 gatagcctat tttagtatag gtttgcttga tctcttcgat tttttctggg tcgtctgaca
    26521 agtcggtctt tgtcaaaaaa ataatcggtt cgatcgactc gtattccaag gtaactagaa
    26581 agcggtcaag tagattataa gaaaatgcag gctctacgat acttgtgaca atgattccaa
    26641 gatcaacatt tgtgactggt gggcgaacta attgattttt tctcggcaag atttccagaa
    26701 gatagccgtc tgtttgattt tcactctcaa agatcacctg atctccgaca agcggcgtga
    26761 ttttccgatt ccggaaattt cctcttcctc ttgtttgata ggtctctccg tttgcgtata
    26821 catagtaaaa accgctgatt gcttttctga tttgtccttt gataagtgcc acctccgttt
    26881 ttgtttattt taccatacga agaggaaagt aggtgttatt ccatgcaaac ttctcaaagt
    26941 atatggcttg aaaattgatc aaaagagata gaaacacaaa aaagagaatg caacaaatca
    27001 atgtcgcatt cccttctgat atattttatt cagcacttat tttgaacttt ctgaggtgct
    27061 agctgatgaa cttgtggagc tggaagattc ttctcttgaa gagttgcttg tgctactgga
    27121 gctacttgag ctgctagaac tgtctgaaga gtctttttca gaactagaag acgctggatc
    27181 tggtccttta gagtaaatta cgttcacaac cattcctttg gtaattgtcg ttcctgcccc
    27241 tggtactgta cgaatcactt tatctttatc caccgtgttt gaatattcgg aagtctcatg
    27301 cccgatatat tctgcaccga cactagctaa ataactttgt gcttcgcttt ttgtatagcc
    27361 ggagatatca ttcaatttag gctctgttcc ttggcttacg acaaaattga tgtaagtttc
    27421 ttctgctaca acttcacccg aggctggatc ctgactgatg atcgaacctg atggtacagt
    27481 gtcgctatag tcataagtag cactaatatt attgatattg aatccttgtg taacaagcca
    27541 attacgaaca gtttcgtagt tttctcctac atgactactc aaagtcactg tttctggtcc
    27601 tttgctgact gtgaaagtaa tcgtgtctgt tttaggatcg acttctgtat cttctgatgg
    27661 agattgcgaa atgatcattc cgctttctac ctctgaactg aattcctctt ctttttgaat
    27721 caagtcagca gaaaacccta attctttcaa acttgcttcg gcatcttcat aacttttacc
    27781 actgtaatca tctaatttga tttttttcgt gccgctacta atatacagag tgacttcgcg
    27841 tttttgcttg actgtcgttc ccgctgccgg gtctgtcttc actacattac cttcttcgat
    27901 tttgtcatct gcaatttctt ctgtttttgt tgctacttct aatttcgctt ttgcgagtgt
    27961 ttctctagca gaagcttcag aaagatcaga aacatcagga acaacaactt ctcctcgccc
    28021 gccagaagca aagaatacag ctgttccgat tcctaaaaca gcaagaatag ctaataggat
    28081 cagccaccat tttttctgtc ctttcttttt aggatcaggc agaacttctt cctcctctgg
    28141 caaggtttcg ttttctggct tgtcttttgg cagaggcata gatttgaatg aatcaggcat
    28201 tggtgcatct tccgtaaggg gtgtgataac ttttgtttca ttatccatca catgaggctg
    28261 ccatttttct tcgtttgcac gagctggtga taatactgta gaaagatcat cagacatttc
    28321 ctcggctgac ttataacggt ctgcaggttc tttagccgtt gcccgtaaaa tcacgttttc
    28381 cagtgcttgt ggcacatttg gatcaagtgc ttttatagat ggaagatcat cttgaaaatg
    28441 ttttaaagca attgttacag cagattcacc atcaaacggt acgctacccg tcaacatctc
    28501 ataaaggatg atccctaaag cataaatatc tgactgcttc gttgccatac ttcctctggc
    28561 ctgctcaggg gacagataat gaacagatcc cagcatcgta ttcgtctgcg tgatcgatgt
    28621 ttcagataaa gcgatagcaa tcccgaaatc cgtgattttt acaacacctt cattatcgat
    28681 cagtacgttt tggggtttca aatctcggtg gatgatttga tggttatgag ctaaagaaat
    28741 agcagaaagg atctgctgca taatatttac tgctgtttca taaggaacag gataatgtgt
    28801 ttggatatat cgtttcaagt ccattccttt gacgtattcc atcaccagat actgcatgtt
    28861 gtcttcttca ccaacatcgt aaacactaac aatgtttgga tgaacgagtt ctgttgctgc
    28921 taaagcttct ctctgaaatc gtcgaatcgc agtctggtca ttttgaaagt caaatcgtaa
    28981 gactttaact gctacatcac gatccaagat taaatcgtgc gccaaaaata catttgccat
    29041 accaccgcta ccgatatttc cagtgatttg ataacggcca tttaattttt tgcccaactc
    29101 gatcatacac tgtcctcctt atattcgata agaagaacgg tgatattatc cgctccgcct
    29161 gcttcattgg cacgatcaat cagctcagtt actttatgag acaatgggcc ttcttgattg
    29221 atgatcgttc ctatttcttc ttcagacagc atgttcgtca agccatctga acataacagc
    29281 agtcgatctt ttagttgcca aagatgagta gaaacatcta cttcgactgt tccaggcatg
    29341 ccgacagaac gtgttaaaat atttttcctt ggatggttca ctgccatttc ttcgctgatt
    29401 tctcctgatt tgactagttc attgactaaa gaatgatcct ccgtcaattg catgatttta
    29461 tcttcacgaa tcaaataagc tctgctatcc ccaacattgg caatcgtgaa ccagtcatct
    29521 gacagagcgg ccgctacgat tgttgttccc ataccgttat attccggctg ttcttgtcca
    29581 cgctgataaa tcagcatatt ttcttcctga atcgattgaa tgaaccattg ggcgattttt
    29641 tcatcgtcaa cagcttcttg tttttcccaa gcttcgccta gattcgttac cgccatctga
    29701 ctggcaatgt ctccggcacg atgaccaccc atcccgtctg ctaatacagc aagcttgaga
    29761 cctgaacggc tggtaaatac actggcatag tcttgatttg tgttacgtcg tcttcctaca
    29821 tctgattgat attcaatctg cattttttca cctcattact ttttgcgcaa acaacaaatg
    29881 aaaaatccat ctgtgtaaaa ctgatgcgga tacaaagtca acattttctc ttcgattgat
    29941 gattgtagca taggattggt caaaacatca atcctctcaa aatcagggtg tctttccaag
    30001 aaagcagaaa caacgtcttg gttttcttct tttaagatcg tacaagtgct ataagtcaga
    30061 ataccggaag actttaaagt tggtgcgcag ctttctaaaa tttccaattg gatttttggt
    30121 aaattcgcta attcatccgg ctgtttttta taacgaatat ctggttttcg ccgaagcagc
    30181 ccaagacctg aacaaggcgc gtctactaaa atccgatcaa actgctctgc ttcgaactgt
    30241 ttactgactt ctctagcatc catcttttga gcgtagacag cagaagagac acctagacgt
    30301 gctgcattat cttcaatgag tttgactttg tgttcgtgta catctaaagc gaccacttct
    30361 ccaccgcatg acggatctaa aaaagaagca atatgcgtcg tcttacctcc gggtgctgca
    30421 caggcatcta agacatgatg ttcaggctcg atttgcatag acggcgctac aagcatcgaa
    30481 ctttcatctt ggatcgtcat gacgccatcg tggaacaatg agctagaagc taaatgccct
    30541 tttttcgcta ctataccgta tggactgact tggctttttt cagctgtgat ctcttcttct
    30601 tgcaaaacag tgatggcctg atctctggaa agtcggcgtg tatctactcg ggcactagca
    30661 tggctaggct gatatagcga taaaccgagc ttttcagttt cttcgtatcc gatttgatcc
    30721 accagtcgtt tcgtcatcca tagaggcagg ctgattttga cagaaagtct ttcgatagga
    30781 tcagcaatgc cttgcagatc tggtgctcct tgacgctgat aattcctcaa gacaccattt
    30841 acaaatttcc ctgtcccagg atttcctttt acttttgcga tttcgaccgc ctcgtttaaa
    30901 atagcatgtg cagggacttt atctaaaaat tctaattggt atacagaaag ataaagaagc
    30961 gtcttgaccc agtcatccac tttttttgct ttagcgatca atggtgcaac gtaaaattcc
    31021 aatagtcgct gatggctaat cgtaccatag atcaattctg taaataaacc cacatctttt
    31081 tgatttagct cgctttgttt gatcatctca ttcaacaaaa gattcgagta ggcgccaccc
    31141 ttgttcactc gctctaatgt cagtaatgcc atatatcgta ctgatttttt cattttttta
    31201 gggatttttt tcattatttc acctgctgac caatctgaac ttgctgaccg cttccgttaa
    31261 ggaaatcatg tacggcctgt tttcctttac cagctggctg taattcattg atggctaaga
    31321 cggtctgttt accgcaagca atccatagat tttttttgtc tttccggatg atcgtaccag
    31381 gtgctttgtc tgtagtttct gccaatactt caaccgataa taatttccag cgtatgccct
    31441 cataggtcgt gaatgcaatt ggccaaggac gcattccgcg tacttggttg tcaatttctt
    31501 ctgcagtttt atgccaatcg attgcttctt gttcccgtgt gatgtttggc gaaaaagttg
    31561 cttctgactc gtcttgaggt actggttttt gtccatccaa aatattgggc aatgtttcta
    31621 gcaatagctt tcttcctaaa aggctaagct tttcaaacat cgtccctaca tcatcttgtt
    31681 tagtgattgg tatgctttct tgcgcataga ttccgcctgc atccattttt ttgatcattt
    31741 ccatgatcgt tacaccagtt tctttctccc cattcatgat ggcataatga acaggcgcac
    31801 ctccccgata tttaggaagt aaagaagcat ggacattgat tgcccctaat tttggtactt
    31861 gcaataactt ttcaggcaag aattggccaa atgccgcagt gacgatcaca tcaggcacca
    31921 attcaatgat ttcttccatt tctggcgaac cggagatttt ctctggctgc agcacacgga
    31981 taccgtgctt cagagccgct tcttttaccg gtgtcggcgt aattactcgt ttccgcccaa
    32041 ctggacggtc gggctgtgtt accactgcct ggatctcgta acctgattct atcagccctt
    32101 caagaatcgg cacagaaaaa gcaggtgtgc ccataaatac tagcttagtc atcaagatgt
    32161 tcctccatat attcttcaag ttcttcttcc gggatctgct gtatcatttt ctcaatgaac
    32221 aagataccgt ctaagtgatc gatttcatgc tggaaggcac gggctaaata gccaaaagcc
    32281 gtcacttcta tctcttctcc gtctcgatca taataacgca cggtcacttc atctgctcgc
    32341 ttgaccgttc catagacatg cggaatactg agacaacctt ctacgtcaag gctttcacct
    32401 tttgcttcga tgatttctgg gttaatcagt tcaaatttct cgccttcatc tacttcgatc
    32461 acagcaattc tcttgttttg tcctacttga ggagcagcga tccctattcc gtcattcgca
    32521 atcattgtct catataaatt gtctaataaa gcgattgtct cgtccgtgat tacatcgatt
    32581 ggctgagcag ttctttttaa tttatcatta gggtggatca atataggata gcgcataatt
    32641 tggccctttc ttaaataaag tttaatggtt cgttgtcaat tgccacaaaa agaccttgtc
    32701 gctgttcttt ctggcttcca ttcaaaattt catccaaaac atgaggaaga ttcggttcat
    32761 gtttatattt gatgattagt tgataataat atcggttttt cactctcaaa atcatgctgg
    32821 gcgttggccc taatagcaag ctttgagggc ttaacacttc ttttagctga ttggcaatct
    32881 gaaagatttt ctttgccgct acttgttctt caggatggct ggcggttatt ttcacagtaa
    32941 agtaataagg aggatagcct ccacgatgcc gtacatgcat ttcctgctga taaaactgct
    33001 cataattttg ttttttagct aattctatgg cgtaatgttg aggattgaat gtttggatca
    33061 cgacttcgcc tgctttttcc gctcgccctg ctcgtcctga aacttgggta agcaattgga
    33121 atgtatgctc actagaacga aaatccggta aattcaggga ggtatcagca ttcaacaccc
    33181 caactaatgt cacttctgga aagtccaaac ctttagcaat catttgtgtc cctaataata
    33241 tatctgcttc ttttgcaccg aatttttgta aaatctgttc gtgtgcccct tttcttcgag
    33301 tggtatctac atccatacgc aaaatcctag cttgcggata aagttctcgg agttcctctt
    33361 ctactttttg agtacctgtt ccatagtagc ggattttatt gccgccacaa ttaggacagc
    33421 gattgggaat aggttcttca tgtccgcaat aatggcagcg cattgaacgt gtatccatat
    33481 gcagtgtaag agagatatcg caattaggac atggaagaac aaatccacag tccctacaca
    33541 tcacaaaaga cgaatatcct cgacgattga gcagtaggac agtttgttct tttttgtcta
    33601 atcgattttg tattttttcc tgcaaattag cagaaaaagt agaggtccga tgattctgaa
    33661 actcttcacg catatctacg atctcaatag ctggaagctg tgcagctgct ttggctcggt
    33721 ggtttaactg caataactga taaacgcctt tttgagctcg tgctcttgat tctaaagagg
    33781 gcgtcgcgct tcctagaact attgggcaat gatgatattt actgcgccaa attgctagat
    33841 ctctcgcatg ataacgcggt gtctcatctt gtttgtaact tgattcatgt tcttcatcga
    33901 taatgatcag cccgatattt ttcagcgggg caaaaatagc agatcgtgcg cctactacta
    33961 cttgcgcttc ttcccgctca atcttgcgcc attcatcata tttttcacct tgggaaagtc
    34021 cgctatgtaa gaccgcaact gattctccga agcgtccttt gaatcgctcg accatttgcg
    34081 gagtcaatgc gatttcaggc actaacataa tagccgtttt attttctgac aaaacatcag
    34141 cgattgcctg aagatatact tctgttttcc cgctgccagt gattccctcc agcaaaaaga
    34201 cctgatcttt ttgctgctga cctgctgtga tgatttgttc gacagcattt ttttgttctg
    34261 cattcagttc caatgccgtc gtttggtcaa atactcggtc tttataaggg tcgcgataac
    34321 gttctgattc tataaactcc agccagccct tttcttttcc ttgattcaag acagcagtac
    34381 tgattccttt atttttgaaa taagcaattg gttcttcttg gctcagttca gataaacaca
    34441 aaagaagttc tttttgtttc ttggcatttt gccgtaattt tgcccattct tcttcgattt
    34501 gcttttcagt taacaaagaa cggaccaaac gaatcgtttt tactttattt cgtgtatgga
    34561 cttcatattt gatatctact aattgctctt ggcgccagcg aatcaattga gaaaggctgc
    34621 cttcttcttc tgcttccttc caggaaatca cttctcgctg atcaaacaat acctgaactt
    34681 ctggtgtgtc tgccaaagga tagatcaatt tatcatattc tgctttcatc acactcggaa
    34741 gcatcgtttg tagacaagtg attttgaatg cgtaagtaat ttttttcata taatcagcta
    34801 atgaaagtaa ttcttcattg accaccggag caaggtctag caaacgaata actgccttca
    34861 aagatggatt agctgattct tctgattttt ggatagccat aacaaatcct tggacatgac
    34921 gattgccatt accaaaaggg acttctactc gcatcccgac ttgcaaagct gtttccattt
    34981 cagagggaac caaataagtg aatggctgat cggtctgcat agtaggtacg tccacaatga
    35041 cttcagctgt taatgtcatg gttcgtttcc tccttttttt gtcttttctt atcaagcgac
    35101 aaaaagttcc ttgcctattt tactagagat cgatggattt gtcttatctt ctgccaaatc
    35161 ctaacaaaaa attaacagca gataagaaaa aaaagaactg tgtcaaaaag ttcagacaca
    35221 gccttttcta ccagacaata agtggcgaat gtttgaaaag gaaacagctg ggtttgcttt
    35281 tctttttaga tgttcgctct atttttcttt attacatttt ttgctcttca cggatacgtg
    35341 attccaattc gtgttgttca cgctcttttt gtgcttgacg ttcctcttct tccatcttca
    35401 aacgttcacg ttttaattca ggatgtggat cattgactac atttcctgca tcgatttctt
    35461 ctaaagcttg accgacgctt tttactgaat caaaagaatc tagagtaggc tgtgcacttg
    35521 catccaattc atgcgcgcgt ttacttgcta aaatcactag agaatatttt gaatttacac
    35581 gatctaatag tgagtcaatt gaaggtttta acatcataag actacatctc ctttaacatt
    35641 ttaatatatt taccgattac gcgatctact cgaaaatgtt cactggcaat aatgtttttg
    35701 attcgttcaa ctgctagcgg cacttcatca tttacaacag catagtcgta aagagccatc
    35761 atttcgattt cttcttttgc aactttcatt cgttcttcga ttacttcatc tgcatctgtt
    35821 cctcggccta cgatccgtga ttttaattcc gctaaatctg gcggagtcaa aaagatgaat
    35881 acaccatcgg gcactttttc tttgacttgt tttgctcctt ggacttcaat ctccaagaaa
    35941 acatcttttc cttcatccaa tgtcttgttg atatatgaca aaggagttcc ataataattc
    36001 ccgacatatt ctgcgtattc cagcatctct ccagcttcga tcattgattc aaactcttct
    36061 ttgcttcgga agaaataatc aacgccttcg acctcccctt cacgcatttt acgggtagtc
    36121 attgagatcg aatactgaaa atcattatcc tcactctcaa aaattgcttt tcgtactgtg
    36181 ccttttccta caccggatgg accagacaac acgattaata atccacgctc tgacatgacg
    36241 acgtcctttc aactagtctt tttgtactta tcgtttattt tgcacttttt ttctgcaact
    36301 ttcaaggtta tctttaatta tagctagaaa ttggtaaaaa agctaccctg taccaagagg
    36361 tcgtaaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacataaac agcttctcat
    36421 gtttttcgtt tggttggggt tattatcgca gatgcaagct tttgaacgcc gtgtataaga
    36481 ggtcgtgaag aagccgatta gtttcgagta tgaagaaaaa ttttgtgaaa atagtttctc
    36541 acatttttgc ataaatttgg cttaata
//
LOCUS       DAIGTA010000024        36537 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.024, whole genome shotgun sequence.
ACCESSION   DAIGTA010000024 DAIGTA010000000
VERSION     DAIGTA010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.024"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..178)
                     /locus_tag="NOB43_001269"
     CDS             complement(<1..178)
                     /locus_tag="NOB43_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0982139.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLY"
     gene            382..1032
                     /locus_tag="NOB43_001270"
     CDS             382..1032
                     /locus_tag="NOB43_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI0982140.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            1048..2775
                     /locus_tag="NOB43_001271"
     CDS             1048..2775
                     /locus_tag="NOB43_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982141.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            2772..4664
                     /locus_tag="NOB43_001272"
     CDS             2772..4664
                     /locus_tag="NOB43_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982142.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            5368..6237
                     /locus_tag="NOB43_001273"
     CDS             5368..6237
                     /locus_tag="NOB43_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HCI0982143.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            6446..7471
                     /locus_tag="NOB43_001274"
     CDS             6446..7471
                     /locus_tag="NOB43_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI0982144.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            7510..8460
                     /gene="manA"
                     /locus_tag="NOB43_001275"
     CDS             7510..8460
                     /gene="manA"
                     /locus_tag="NOB43_001275"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HCI0982145.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            8554..10257
                     /locus_tag="NOB43_001276"
     CDS             8554..10257
                     /locus_tag="NOB43_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0982146.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            10259..12292
                     /locus_tag="NOB43_001277"
     CDS             10259..12292
                     /locus_tag="NOB43_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0982147.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            12303..12743
                     /locus_tag="NOB43_001278"
     CDS             12303..12743
                     /locus_tag="NOB43_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0982148.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(12943..14070)
                     /locus_tag="NOB43_001279"
     CDS             complement(12943..14070)
                     /locus_tag="NOB43_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982149.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(14073..14750)
                     /locus_tag="NOB43_001280"
     CDS             complement(14073..14750)
                     /locus_tag="NOB43_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982150.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            15014..16780
                     /locus_tag="NOB43_001281"
     CDS             15014..16780
                     /locus_tag="NOB43_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCI0982151.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            16795..17232
                     /locus_tag="NOB43_001282"
     CDS             16795..17232
                     /locus_tag="NOB43_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0982152.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            17245..18396
                     /locus_tag="NOB43_001283"
     CDS             17245..18396
                     /locus_tag="NOB43_001283"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCI0982153.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(18458..19156)
                     /locus_tag="NOB43_001284"
     CDS             complement(18458..19156)
                     /locus_tag="NOB43_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HCI0982154.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(19149..20501)
                     /locus_tag="NOB43_001285"
     CDS             complement(19149..20501)
                     /locus_tag="NOB43_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HCI0982155.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(20724..22124)
                     /locus_tag="NOB43_001286"
     CDS             complement(20724..22124)
                     /locus_tag="NOB43_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HCI0982156.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            22315..23022
                     /locus_tag="NOB43_001287"
     CDS             22315..23022
                     /locus_tag="NOB43_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HCI0982157.1"
                     /translation="MKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCCAPCSTHTLEF
                     MSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIVDEYRPNEFTK
                     MVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISPKKNAALINQI
                     GMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAKQQGCDLKEIN
                     REAKAYLKTSTVVFEEN"
     gene            23147..23626
                     /locus_tag="NOB43_001288"
     CDS             23147..23626
                     /locus_tag="NOB43_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HCI0982158.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            23623..24390
                     /locus_tag="NOB43_001289"
     CDS             23623..24390
                     /locus_tag="NOB43_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982159.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            24620..25189
                     /gene="lepB"
                     /locus_tag="NOB43_001290"
     CDS             24620..25189
                     /gene="lepB"
                     /locus_tag="NOB43_001290"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0982160.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(25293..25895)
                     /locus_tag="NOB43_001291"
     CDS             complement(25293..25895)
                     /locus_tag="NOB43_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0982161.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            26001..26470
                     /locus_tag="NOB43_001292"
                     /pseudo
     CDS             26001..26470
                     /locus_tag="NOB43_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            26576..27160
                     /locus_tag="NOB43_001293"
     CDS             26576..27160
                     /locus_tag="NOB43_001293"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCI0982162.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            27163..28236
                     /gene="prfA"
                     /locus_tag="NOB43_001294"
     CDS             27163..28236
                     /gene="prfA"
                     /locus_tag="NOB43_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCI0982163.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            28229..29068
                     /gene="prmC"
                     /locus_tag="NOB43_001295"
     CDS             28229..29068
                     /gene="prmC"
                     /locus_tag="NOB43_001295"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCI0982164.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            29061..29240
                     /locus_tag="NOB43_001296"
     CDS             29061..29240
                     /locus_tag="NOB43_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982165.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            29262..30287
                     /locus_tag="NOB43_001297"
     CDS             29262..30287
                     /locus_tag="NOB43_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCI0982166.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            30462..31706
                     /locus_tag="NOB43_001298"
     CDS             30462..31706
                     /locus_tag="NOB43_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCI0982167.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            31859..32806
                     /locus_tag="NOB43_001299"
     CDS             31859..32806
                     /locus_tag="NOB43_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0982168.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            32940..33569
                     /gene="upp"
                     /locus_tag="NOB43_001300"
     CDS             32940..33569
                     /gene="upp"
                     /locus_tag="NOB43_001300"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCI0982169.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(33708..33950)
                     /locus_tag="NOB43_001301"
     CDS             complement(33708..33950)
                     /locus_tag="NOB43_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982170.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            34071..34143
                     /locus_tag="NOB43_001302"
     tRNA            34071..34143
                     /locus_tag="NOB43_001302"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34104..34106,aa:Thr,seq:cgt)
     gene            complement(34262..34900)
                     /locus_tag="NOB43_001303"
     CDS             complement(34262..34900)
                     /locus_tag="NOB43_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0982171.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(35023..35655)
                     /locus_tag="NOB43_001304"
     CDS             complement(35023..35655)
                     /locus_tag="NOB43_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI0982172.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            36006..36305
                     /locus_tag="NOB43_001305"
     CDS             36006..36305
                     /locus_tag="NOB43_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI0982173.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        12367 a         6405 c         7388 g        10377 t
ORIGIN      
        1 aataaagttt ctttggatct agatttttta attgtcttgg caagatagca gcggggatag
       61 aaagcgagtg gcttaagtgg ttttttgtgt aatctaaggt atttcttgta tctaaaacga
      121 tgctgtcagc atcgagaggc aatttattga agtcttggac actaattgat tgggccattt
      181 atctcatcct ttgtttagta tgtggctatt ttaatgggca actctcatta attcaaatgg
      241 aaggattcct cttatcactt ttttaatgta tcggatgata atgaaaaaaa ctatgcaaat
      301 gtcttgcaaa acaggtagga ggtgttataa tgacatagcg tcatatgaca atgtgtcatc
      361 ttgaaagaaa ggagaatcca tatgccgaca cagacatttt tccatttgcc taaagaaaaa
      421 caaaaaagac taatcgaggc tgcgagaatc gagttttcta gagtaccctt aaaagaagct
      481 tcgattgcta atatcgtcaa attagcggat atccctagag gcagtttcta tcagtatttt
      541 gaagataaag aggatcttta tttttattac tttgagacaa tgagacgtga cagctctaaa
      601 gatatgttac aactaatgaa agaatccgat ggtgatctat tcaaaggatt cgaatcctat
      661 ttttctaaaa tgatttatga gattttggaa ggcgagaatg cttcttttta tcgtaacttg
      721 tttatgaaca tggattaccg tgcctcaaga aaagtcgctc ctcatacgag tcgccaaaaa
      781 acgcctcacg atccacataa agaacacaaa caagatgcaa aagagttgct tgaattgatc
      841 gatcggacga agctgaaagt aaaaaatgat catgaattgg aattactgat ccaattagtg
      901 atgaatactg tatttacaac aattgcgcat tcgtatcgct tattttcaac atctgaagat
      961 tactcagtag agcaagcaat cagtgaattc aatttgaaac tttcttggct gaaaaacgga
     1021 gtatataaat agaaagaagg gaactagatg ctaaaaatcg taaaacggat ctccttgact
     1081 tcagcaattg cagctgcagt tttcatggtg atccaagtac tggcagattt atatttgccg
     1141 acacttacct ccaatattat tgataaaggg gtagcgcaag gagatgtcga ttatatttgg
     1201 catacaggtt ttgtgatgat cggcttttct ttgatcagta tcttagctgc tatcgcaaat
     1261 acattttttg ctactcgtga atcacagaaa ctgggtaagc aattgcgtac ggatgtctat
     1321 aaaaaatcag agagtctgac aaaagatgcg tttgataaat atggaacggc ctctttgatc
     1381 acaagaacga ccaatgatgt gactcaaatc caaatggtta cacaaatgtt tttacgtatg
     1441 atgatcaatg caccaatcac gttgattggc gcgagcatac ttgcttatca aaaagatcat
     1501 cagttgacaa aaatcttctt agttgtcatc ccagtaatga ttattttgat cggcggaatc
     1561 atgtactttg ctgttccatt attcaaaagt atgcaaaaga aaactgaccg tttaaacctg
     1621 gtatttcgag aaggattgac aggggtcaga gtgattcgag cattcgataa gacacgcttt
     1681 gaagaaaatc gttttgattt agcgaataaa gattatacaa atacggcaat caaagttaat
     1741 acgatcgtcg cattgatgat gccaatgatg acattgatca tgagcggtac aaacgtagca
     1801 atcacttggt ttggtggaca ctacatagca gatatgactt tggaagtcgg taatctgatt
     1861 gcatttatga cttatgcgat gcagatcttg atcagcttta tgatgctttc cgctattttt
     1921 atcatggtgc ctcgtgcaca agcttcagct gaccgtatta atgaagtgtt ggatgaaaaa
     1981 atcggtatcc atgaccctga aaatcctaaa acagtttctt ttgctggaaa aaacgcaaca
     2041 ttggccttca atcatgtcaa ttatcgatat catggagcag aaaaacttgc attggaagat
     2101 attgatttcc aagccaagtc gggcgagatc gtcgcaatca taggggggac tggttcaggt
     2161 aaaacgacct tagtcaattt gatccctcga ttatatgaca tcgaatctgg ttcgatccaa
     2221 ataaatggaa cggacattag tgacatgact caatataatt tgcgagaatt aatgggcttt
     2281 gttcctcaaa aagcagttct gttctctgga acgatccgag acaatatgca gtatggtaag
     2341 ccggatgcaa cagatgaaat gatttggaaa gcattagaaa tcgcacaagc taaagatttt
     2401 gtttcagaga tggaagatgg cttagatagc catgtggaac aaggaggagg aaacttctct
     2461 ggtggacaaa gacagcgtct ggcaattgca cgggcattag tcaaaacagc agatatctat
     2521 gtgtttgatg attccttctc agcgttggat ttcaaaacgg atgccaatct tcgccaagca
     2581 ttgaaaacga atatgaaaga aagtatcacc gttttagttg ctcaacgagt aagtacagta
     2641 atggatgcag atatgatcct tgtgctagat gaaggaaaac tggttggcaa aggaacacat
     2701 gaagaactat tagcaacaaa cgaaacttat caagaaatcg ttcattcaca actaagagag
     2761 gaggacttag catgagtaaa acaaacacac gtccctctca tggaccagca ggcggtccag
     2821 gacatggtgg acctggcaga aatctcggtg taaaaggtga aaagcctaaa aatttctggg
     2881 gaacggtacg ccgattgttt ggctatatgt ctaaacgtat ggttgcgatc atcgctgtat
     2941 ttgtactagc aatagcagcc gtgatcttcc aaatccaaac accaaaggtc ttggggaaag
     3001 caaccacaga aatattcaaa ggtgtaatgg ctggcgctca acagatgcaa caaggccaac
     3061 aagtaacaaa atttccgata gactttgata aaatcgcgca gatcattgcg acagtaatcg
     3121 tgatgtattt gatttctgct gtattcaact ttttacagca atttattatg acacgtgttt
     3181 cccaacgaac agtttatgaa ttacgtcatg atttggaagc caaaatgaat cgtgtaccga
     3241 tttcctatta tgatacacat acaaatgggg atatcatgtc tcgagcaatc aatgatatgg
     3301 ataacatcgc aagcacgctg cagcaaaatt tgactcaatt tgtaactagt gcagtcacat
     3361 tgattggggt catcgtgatg atgctttcaa tcagctggca attgacgtta gtcgcgttat
     3421 tgatgatccc tttaagcttg atcatcgtga tgatcgtagc gccgaaatca caagtgtttt
     3481 tcgcagatca gcaaaaaagt ttaggtttat tgaataacca agtagaagaa acatatggtg
     3541 gtcataccat tgttaaaaca ttcaatcata ctgaaaaaga ccaggaagta tttgaaaaag
     3601 aaaatcagaa tctgtatgcc gctggttgga aagctcaatt tatttcggca atcatcatgc
     3661 cgttgatgaa tttcgttaaa aatctaggct atgtgttcgt cgctgtacta ggcggagtaa
     3721 aagttgcaaa tgggaacatg acattagggg atgttcaagc gttcttgcaa tatacaacac
     3781 agttctctca accaatcact caacttgcaa gtttgatgaa cactatccaa tcaacagttg
     3841 cttcagccga acgggtattt gaagtgttgg atgaagaaga gatgtccaat gaaaaatctg
     3901 gccttccaga agaaaaagat acaccataca aagttcgttt tgaaaatgtt caattcggct
     3961 acacaccaga taacttgcta atgactgatt ttaacttgga tgtcaaacct ggtgagatgg
     4021 tcgctattgt aggtccgact ggtgcaggga agacgacact gatcaacctt cttgaacggt
     4081 tctacgatgt ttctggaggt agtattcgtt acgatggtgt agatacccgt gatctttcac
     4141 gtgatgaatt gcgcgcacag ttttcaatgg tactgcaaga tacttggctg tttacaggaa
     4201 gtatctatga caatatcaaa tatgggaacg acgatgcaac agacgaacaa atcattgagg
     4261 ctgctaaagc tgctcacgta gacgattttg ttcgtaaatt gccagaagga tataacactg
     4321 tattaaacga ggatgcaagc aatatttcgc aagggcagcg tcagctaatc acaattgcgc
     4381 gggcattctt agcaaatcca gatgtcctga tccttgatga agcaacatct agtgtagata
     4441 cacgaacaga aatactgatt caaaaagcga tgaaccgcct attggaaaac cggacaagtt
     4501 tcgttgttgc tcaccgcttg tctacaatac gcgatgcaga caacattatt gtgatgaatc
     4561 atggttcgat cgtagaaaca ggaaaccacg atacattgat ggaaaaagac ggattctatg
     4621 cagatcttta taacagtcag ttttctgaag aagaagcttc atagaatagt acaaatttat
     4681 tatttttttt aggggctgtg acaaaagtcg tgtcacagtc cctttttccg aataaacggt
     4741 gttcaatcag ctgtccttcg gtattagctc aaaaaacggc aaaatatgag aagctatttt
     4801 tccgttttgt atctctaata ctcaggtcaa accgctgatt ttacaacctc ttccttaaac
     4861 ggtgttctcc tgccaactcc tcggtcacaa gtcacaatag tcaacaaacc tgagaagctg
     4921 ttttttgaaa ttgctccttg tgactcggag ttaaacggca ggctcacaac ctcttggtaa
     4981 acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa tgtagaaagc
     5041 cattttcaca aaatttttct tactactcga aactaagcga ctttttcaca acctcttcct
     5101 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaataggag
     5161 gagctatttt tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaacctct
     5221 ttttataaga gtttttactc attaatttac aaaaaacaag caaaatgcga attttctcac
     5281 atttttttta acaaaatcaa agttattgct tgaaagaaga agaatccatc gttaaaataa
     5341 agcttgacgt agaggggagc aagaaatatg aaagattttc aattgggggc tgccacctat
     5401 ttaaaaagtg tagccattcg ggtgaaagac cgagataaaa tgattgattt ttacaagaac
     5461 gttgttggct ttgatttgaa aagagaagaa aacgaattag ccattttagg aacagaagaa
     5521 gctggaagtg aaatgttgct gctggaagaa agtcctagag cgaatgatca catgggggtg
     5581 atcaaaaagc tgaaccgttt ttcattgatt atccctagca cagaagaaat ggcagatatc
     5641 ctttgtcgta tccgtaaaat gaattatcca atcaaagaag ctttagaaga tcatggacgt
     5701 atggggattt tgctcgtaga cccagaagag aatgaattgg aaatttacca tgaagagaat
     5761 aagaacgacc aaagagaaat tccagaaaca atggatcaag aagcattatt aagaaaatct
     5821 gaagaaaaat tcagtaaact atcaacaggt tcttattttg aaaaaatcca tttaaatgtt
     5881 actaacttaa caaaagaacg ccaatttctt aatcatgtac ttggtttgaa ggtacataat
     5941 gaagaagagg gcatccatgt attgaatgaa ggagatttcc atgttggttt gacagaagct
     6001 agcggaggcg caattgattt gcctacagat gaagtgattg gacttgattt tctgaaattc
     6061 atgatcgata ctgaaagcat ggaaggactg attgctcact tgcagcaact atcagttgat
     6121 ttcttcttag acaaaaagca cacagtactc acaatctatg atgctatagg aatcgaatgg
     6181 tggttcgtca gtgagccaaa agaaaagaat aaaactgaca ttcgatgcga cgcttaactt
     6241 tttctttctt aacgattgtc gcatgtctcg tcattttatg aacggtcata ctatcgctta
     6301 ttctagagat agaaagagaa aatagtatac cgggggaaac tgcgcggttt ttcgcgcagt
     6361 ttttttgtgt aaaaaaggtt gattcctcat agattaagct ttaagcttgg actgtaagaa
     6421 tctgatagaa aagcaggaga aaaagatgta tccacacacg aaacagctta ttttgaaaaa
     6481 gatggaagaa ggattttatc caggtgtagc agtcgccttc ataaaagaaa atcaagtaga
     6541 aacatttaca gccggctttg cccaagtcgt tcctgaaaag cagctgatga cagaagatct
     6601 gttgtttgat gcagcctcac tgacgaaagt cgttgcaacc acttcattag ttttacgtct
     6661 attagaagat ggaaagatag aactcgatca accgcttcat aaatatcttc ctgaatttga
     6721 aaatcagaca atcactttgc gtcatttact gacacatact tctgatatca aaacatggat
     6781 accaaacaga gataagctat ctcaggaaga attgatcgcc gcttatttga agctagaacc
     6841 aggtgagcaa ctaggaaaag aagtaaaata tacagatgcc ggtacgattc ttcttgggtt
     6901 gatgctagag gaaatttacc aagaaactgc agtggaaatc tttcaagaac aagtattgga
     6961 accattagga atgatgaaca gcttatttct tccttttcct tccaaaaaaa tcgttcccac
     7021 agaacaactg ccttcgggtg aggttttgcg tggacaaact catgatccga aagcaagagt
     7081 tttggctgaa catgcaggta acgcgggtct ctttattgat ttgaaagaca gcattacttt
     7141 tgtccaaatg tatttgaaca agggaaaaat ccgtaatggt cgttttttag aagaagagac
     7201 gattgattct ttactgcaag atcaaacacc gaaaaaaaat ggctatcgtt ctttaggatg
     7261 ggacttaaaa aaggatgtag aagacggtca tgcgattctt tttcatactg gttatacagg
     7321 tacgtttttc ttgattgata taaaaacaca agaagcgttg atatttttgt caaatcgcgt
     7381 acatcctgtc gatcatcgtg cggagtatct catatgtcga gatgaaattg ttgaaaactt
     7441 tttgaaagag aaagcggtat taccgaaata atgctataat agctatgaaa aatgagagga
     7501 gtttgaatta tgcaggaacc tatgttttta aaaccagttt ttcaagaaaa aatttgggga
     7561 ggaagtcgtt tacgttcagt ctttggtttt gatatcccta acgataaaat cggagaagat
     7621 tgggcgatca gtgcgcatcc tcatggtgtc agtgtagtag aaaatggcga attcaaaggg
     7681 aaaagattag atgaactatg gtcagaacac aaggaattgt ttggccatcc ttcagaacca
     7741 gtgtttccat tattgatcaa gatcttagac gcagaagatg atctatctgt acaagtacat
     7801 ccagatgatg cctatgggat gaaacatgaa ggtgaattag gaaaaactga atgctggtat
     7861 atcatcgatg ctgaacctgg tgcagaaatc atctatggtc atcatgcaaa gacaagagaa
     7921 gaactagctg agatgatcaa agatgggcgc tgggatgacc ttttgaagaa agtaccagtt
     7981 aaaaaaggtg atttctttta tgtaccaagc ggaacgatcc atgctattgg taaaggaatc
     8041 atgattttag aaacacagca aagttctgac acgacttacc gcgtgtatga ctacgacaga
     8101 aaagatgcgc aaggacaaac aagagagctg catatccaac aatcgatcga tgtaacaact
     8161 gtccctgcga aaacaccaga attacaaatc aaagaagtcc gaaaagggaa ttcatcgatc
     8221 gtcacttatt tagaaactga gtttttcaat gtatatgagt gggatattaa aggaatcaca
     8281 tctttcaaaa aacaagcccc ttatacattg atgacggtaa tcgaaggagc aggagacctt
     8341 gtcgttgacg gaaaaacata tccattagaa aaaggaacaa gctgtattat tccaaatggc
     8401 gtttctgagt gggcggtcca aggtgaacta gcaatcattg cgtctgaacc aggcaaatag
     8461 ttcccagata gctgaaagca gcagacggtt tttcgtttgc tgctttttct acataaaatc
     8521 cgtccatcaa taaatagaag tctggtgaaa aagatggaat acaaatggaa agcaaacaac
     8581 agcagtcgcg tgtctatgaa acaactgaga aaagctggac atcacttaaa tgaaatgatc
     8641 atgccaaatc taagtctgtt tatcgcttgg ggaatcttgt cattagcaac aaaaggtgtg
     8701 tctggcgatt tgcataccac attagaagag gtatgccatt ggatgatcca gctgctttta
     8761 cccatcttga tcagttattc aggcgggaaa tcggtagggg gacaaaaagg ggcagtcgcc
     8821 ggtgcaattg cttctttagg gttgatcgct cgttccaatg ctccacaaat cgtaggagcg
     8881 atgattatcg ggccgcttgc cggcatcgta tatgaacaat ttgtttctag attccatgtg
     8941 aaattcaagg ctggatatga aatgcttgtc agcaacctac tagtaggact gactggtagc
     9001 gttatttgta taattggaat cgtttttatt gaaccagttt taaatagtgt tcacttgttg
     9061 ctcgcctccg ttgtgtcttg gctagtcaca atgaatctgt taccacttgt cagtctgatc
     9121 ttagaacctc taaaagtact atttttcaat aatgcaatca atcatggtgt attgacacct
     9181 ttaggaatcg aattctcaca aacagtcggg tactcttcct tatttttgat ggaggcaaat
     9241 cctggacctg gtttagggat cttactttct atcctttgtt ttgcagaaaa acaggaaaaa
     9301 gtaaatgcga gtggagcatt gatgatccat gcgattggcg ggattcacga aatctatttt
     9361 ccatttgtct tgctgcgacc gtatctattt ttagctgtaa tggctggtgg ggcaagcggc
     9421 acgttgatat ttcaatggtt agatacggga ttagctgcac ctgtatcgcc tgggtcacta
     9481 ctcgtgattt ttgccaatgc gccttatcca caactagctg gggtaagtat agggatagca
     9541 atcagtacat ttgtgacctt catttgtgca gcgatactat tgaaattacc aaataaagaa
     9601 aaagagaaca aaacggtcaa agaaagggga gaaatcttgg aaccatctat cattcattcc
     9661 gtcatttttg cttgcgactc aggtatggga tcaagtgcta tgggagccgc cctgctgaaa
     9721 aagaaattag cagcagaaaa aatcgatctt tctgtcggat acagctctat ctatgaattg
     9781 aataaccaag taaatcagct ggttatcgtg caacatgaac tagcgggtct tgcaagagaa
     9841 aaagtacctc aaagtcaaat ctatgtactg gatcactttt tggaaacaga tatcttgctg
     9901 tcacgaataa aagaagcgat ccaatttcca aagcgggaag aaaaaaaaga gatagcagat
     9961 atcacagaac aaaaaacgtc gcctgctaat attgtatttt tgtataaaaa caacagacgc
    10021 ggctcacaaa ctatgggcat gacgatttta agtcaattag caaaaaaagc gaaaaaacag
    10081 tttgttatct caaaagaatc aatagaaaaa atcaaaatcc aagaagaaac gatttatatc
    10141 gcacaaagag aactagctgt aactgaacag ctagaagaaa agatccctcg gctagttcta
    10201 gttgaacatt gggtagctac gaatgaatac gaaaaactcg tgaagggaga aatataagat
    10261 gtatttatcg cccagagaaa aacaattatt agcagaattt ctcagtagcc cgtcacctgt
    10321 atctatccaa aaaatgatga atttattgaa ggtcagtaaa cggactattt accgcgaatt
    10381 agataatctt gaagtctcat tgaaatcggt aaatgcttct ttgaaaaaag cagctagagg
    10441 ctcatttgtc attgaggcat cagaagaagt attagagcaa ttaaaagaaa atacagatgg
    10501 gaaaagtaat gacttatcca ctgctaaacg acaacacgcg attttagccg agttgttact
    10561 gacgacagag ccgttgagtc ttgctcattt catggaatca tatcgcatca gtaataccac
    10621 tttttatgca gatatcaaac agttggaaga aagtattcgc caactgcctt tggaaatcat
    10681 tcggaaccag ggatacgaga tcgaaggacc ggaaaaatac cgccggcttc tgacagcgaa
    10741 tgtattagaa ttagaaatca atgaatatga actttttcat agtatttctt tcgatgcatc
    10801 actgaattat ttttttcgat tcgttgatcc gcaacatcta tctcttgcac gcaaagtaat
    10861 cggggaagaa ttgatccaaa aaaagaccaa tctaagtgat agaaagcttg aacatttggt
    10921 tttgatgctg acattgacga tggagcgtgt gacgaaaaat catttactga caaatgagac
    10981 atataatagt ctggcaaaca aagaattact acagacagct aaacgattgt tttcacggat
    11041 cgcttctgag acaaaacaac tttatccagt aaatgagatc gtcttttttg caggattatt
    11101 aaatgacttc acgaactcat ttgatcagaa tttctttgaa gagacgttcg atacacagct
    11161 tgcttattta gtaaaacaac tgattcaaga agtaagtgaa gagacgaatg tccattttta
    11221 tgaagatgaa actttgtaca aaatgctgtt gactcattta tctggtgtgt tttcaagagc
    11281 cgttttacaa gaagagacac tgaccaatcc gattttagaa aaaatcatgg ttcaatacga
    11341 ggaagttgcg aatgcaatcc gtaaagcagt agagcggatt tttcaagaaa aaaaattatc
    11401 cgaagaagag atcgcttata tggtccttca ttttgcgaat tcattggaac gaagtccgaa
    11461 agaaagcaat atcagtattg caggattttc gccaagtgga ttagcttcta ctagcatgtt
    11521 ggaactacga ttgaaaaggt attttccctt catccaacaa attcatttct atcggattgc
    11581 tgatttaaaa aaaatcgatt tacaagaaga atatgatgtt gttatttcta catctatttt
    11641 accaggatac ggtggaaaat atattttagt ctccccgcta ctgctagaag atgaagtcaa
    11701 gcagctaaaa gaagcttttt cgcatattga gaagaaaaaa aggcaaaaaa ttacgtataa
    11761 cagcaataac gagtggatga tagaagatac ttatgaggaa acaatgcatt tcatggatca
    11821 aatcaatcaa ttactcggtc gtttttttat ccaagaactg gataatcctg agacgatttc
    11881 cgaaacgatt cgcagcttat ttccttattt tcctgaagga ctagtaacgg atgaagaggt
    11941 ggttcatcgc cggctgctta agcgatatga acaagcacct atcggtattc ctcatacaaa
    12001 tatggggtta ttccatacat ccagctcatt gatttctaaa ccgatctttt gtattttcaa
    12061 tttgaaacat ccgttgacca ttgaagggat ggatagacag ccagtcgatt tgtcccgtat
    12121 gttagttatg ctggcgcctt cgccaatcca agaaaaagac gggattcttt taggaaagat
    12181 cagtggagca atcatcatga atgacttgaa caccgagatc ttccgctcag gaaataaaga
    12241 aatcgtttat cagttgttag cgaaaatcct gattgaagaa ataaagaaat gaaggtgaaa
    12301 agatgataca gctaccagca gaaaaaatat tgctcgatca atcctatcaa aattggaaag
    12361 aagcgttgac cgagatcggc cagtggatga cccaacaagg gggaatcaaa ccggcatata
    12421 tccaatcaat gatcgaaaga caagaaaaag cgagtgtcta tatcgggaat ttcgtagcct
    12481 tgccacatgg gactgacaaa gatgaagaag tagtagaaga aggaatctat ttagtccaag
    12541 tgcctgatgg tgtggacttt ggaacaaaag aggaaccaaa aatcgcgaca ctcttatttg
    12601 tagtggcttt aaaaaaagaa catcagttag cggtgctcca agatttagcc tttttctgtt
    12661 cagacatcga ccaagtaatg gcgctcagtg atgcggaaac cattgaagaa gtccaaatga
    12721 tttttgaaca tggacatata taaccaatgt tcacagtaaa aaaagctgcc ttgcatcaag
    12781 taataacttc aaccaagata aaaataagag gagctatttt tgttgggagg ttcttattac
    12841 tgcggatgca agcttttgaa aactatttat tctagaaaac cgtttatttg aaatagggga
    12901 cggtgacaag gtttttgtca ccgcccctat tatttttgtg ttttaatagc tcttttttat
    12961 atagatagtg cccataccta tgaataataa aacgatactc catataccaa gtgtcaagat
    13021 accattcatg aaagtaacct gttctgaagc tagtggcgag aaaatatctc ctcctatgat
    13081 cacattttga aaatcaacat aagaagttgg caagtaatga ctgattgatt ctatccatcc
    13141 aatcgaagaa aacaagcgat actctgctaa gaaaagacaa agaagtgtac ctaaaagatt
    13201 gactagagaa tgttcaaata aagcagatag aagaaaactg attgtactta aaaagagcac
    13261 ccacaacaac aggaacagaa agctctggaa aagatactca tacatcggca ggattcgtat
    13321 ctcctgacca atgatcgttc ctacaggata acggaagtct cccaaaccat ttttgattat
    13381 tactagtata gagacgatca aaaatggcat cacgagactt agcatagctg caccataata
    13441 aatggtaaaa cggatgctat gtttctttac catactatcc ggtaatagat tgactagaga
    13501 gattacctgc tttctttttt cataagagat gatggaagaa agaaacaagg cggttataca
    13561 taaaatcaaa aaactagaaa tcattcctga aaaaatattt tcgtagtaat ttgctaaaga
    13621 gagatgcgct ggcaagtcaa aaatagaata tctttggatc tgatgttctt tcatataacg
    13681 gagcaactcg acacgttttt gttgttcaat gattggaatt ccttgtcttt gaccagaaat
    13741 cagtcgatcc agtatatctt tttcataatg ataagttgct tcgaccattt gctggacatt
    13801 ccctgtgttt tttgcatgta agattgcttc gatcagtttg ttgcttttct ctaaactttc
    13861 cacaaattct ttctcattct catcttcttt caacgtttca atcaaacgtt gcatctcttc
    13921 atagttatga ttcagttcat cgaattctgt ataagcaagt ttatgatcaa aaaaaagtgg
    13981 gaatgcaaag agcacgacca acaatagagg aaataaaaag tttactttgt tttttagtaa
    14041 gagattgcgt tcaaatgtaa gtaaagacat agttacacct catataattt acgataaata
    14101 gctaaaatct cttccatatt tgaggattct gtgacgattt ctccattttt tagaaaacat
    14161 gctttagaac aaatcgattg gatattcgcg atagcgtggg aagaaagaag aatcgtcttc
    14221 ccctctttct gccattgtct gatgaggcta ttcaagatat caatacttcc tgggtctaat
    14281 ccgttcaacg gttcatcgaa taacatgaca gatgaatcac tgatcaagta agcagcaagc
    14341 aagacatgtt gtttcattcc tagagacatt tttccaatcg gcaaagtaag gtactcagtc
    14401 atcttcaatc gttggaaaac agtttggcat tctactttgc tctgccaata gtatttgatc
    14461 aaagtcaaat aatcaacagc cgatagatag tcggataact gattcgttga ttctagaaaa
    14521 aagaaagacc ggcgataatc tgtataagca gtaggagaga tgttgtgaag ggacaattga
    14581 tcataagttg ttggcagcag ttgggcaatg ccattcagca aagttgtttt gccaaatccg
    14641 ttcggggcaa tcaaagcagc tacttctcct gattctacta aaagattcaa ttgtcgaatc
    14701 acacgttttt taccacgttt catgttcatg tttttgatca gtaatgtcat agataggcct
    14761 ccaatataaa atttaataac ataatagaat ggaaaacatc taaattaaat gctaacaaaa
    14821 gttattgttt gcatattata aaaaaattaa aataacagtt ttatttaaaa ttgaagtttt
    14881 ctgataccga aatcttttta ttttgctgac atactcaaac ctttggcaca aagtttcgtg
    14941 ccaaagtacg actatttctc tttttagtaa gcggatacaa ttagagtatc aaaaggagag
    15001 agggagagac aaaatggaac ggacgattcc caaaaacaac atttcgctaa aagcgagggt
    15061 acaaaaatta ggcagtactt tatcaagcat ggtcatgcca aatattggag cactgattgc
    15121 ctggggtgta ttaacggctc tatttatccc agatggttat ttaccaaatg aggctttcgc
    15181 taccatggta agcccaatgc taacttatct gattccttta ttgatcggtt atactggcgg
    15241 aaaagtaatt gctggtgacc gcggatcagt tgttggggca attgcaacga tgggtgtgat
    15301 tgtcggaaca gatattccaa tgatgctagg cgcgatgatc atgggacctc ttggtggata
    15361 tgccatcaag aaatttgatc agctattcca aaaacggatc aaatccggtt ttgaaatgct
    15421 agtcaataat ttttcagcag gtcttatcgg ttttggatta gcgttattag gtttttctgc
    15481 gattggtcca gttgtcgatg cattgactca agcaatggca aaaggtgtag agatcatttt
    15541 atctgcccat ttgattccat tgacaagtat ttttattgaa ccagcaaaaa tcttattttt
    15601 gaataatgca atcaatcatg ggattttgac accattggga actgaacaag tagcagaggc
    15661 tggaaaatct attctattct tgcttgaagc aaatcctggt ccaggacttg gcgtattact
    15721 tgcttttact ttgtttggca aaggagcagc aaaatcttca gcaccaggag ccatgatcat
    15781 tcacttttta ggcgggatcc atgaaatcta ttttccttac gttatgatga aaccgttatt
    15841 attcttatca gttataggcg gaggaatgtc aggaagtttc attttccaat tgatggatgc
    15901 tggactaaga gcgccagctt ctccagggtc gatcattgcg attctagcga tgacaccgtt
    15961 caattcttac cttcctgtta ttttgggcgt gattgttgcc gcagctgttt cgtttggtat
    16021 ttctgcagta attttgaaag cggatgcgaa agatacaaat gaagacttcg aaaaatctgt
    16081 tcaagagaca aaggcagcta agcaagcttc caaaggtgcc caaggtattc ctcaaggagc
    16141 tacattctct ggcgtacaaa aaatcatttt tgcttgtgat gcaggaatgg gatcaagtgc
    16201 gatgggcgct tcgatcttga gaaaaaaagt acaggaagca gacttgcctc aaacggtgac
    16261 caatcaagca atcagccaac tgacagatga ctcgaataca ttgatcgtta ctcaggtcga
    16321 actacaagaa agagcaaaac aaaaagcacc gagcgcgcgt tttgtctcag tagaaaactt
    16381 tttgaattca cctcgatatg atgaaatcat tcaagaatta agcagcaagc agaaaacatc
    16441 agtttctgaa attgagaatg agccagcaga agagtttctt tcagcaaaca tcaaacaaat
    16501 caaagagatt ctacttgtcc acgatgatcg ttccggatca gcaacaatgg ggatgaccgt
    16561 gctcaaagat atattagaca agaaccattt aactatcccg ttaagaaaag tcaatatcca
    16621 agatttaaaa gatgaacctg attcactgat cgtagccaaa gaaagtttag cggaaaaagt
    16681 acagatggct gcacctcaat ccattcattt atcagtcaac agcatggtca atccgcaaaa
    16741 atacgaatcg attgcacaat atttgaaaca gacagcttaa gggaggaaaa cagcatgcaa
    16801 agtttgccat tcgacatgat cgagctcaat cgatctttta aaaccaaaga agaagcgatc
    16861 cgctattgcg gtcagatgct tgtagaagca gggtgcgttg atgaggaata tatcgatgcc
    16921 atggtagata gagacaaaat gttatctgtt tatatgggga attttatcgc gattcctcat
    16981 ggaacagatg aagcaaaaaa atatgtgaaa aaatccggca tctgtgtcgt tcaagtacca
    17041 gatggtgtag attttggtac cgaagaagaa gaaaagattg cgactgtttt gttcggtatt
    17101 gcaggagtcg gagatgagca tttgcaactt gtacagcaaa tcgcacttta ttgcagtgat
    17161 atggacaatg ttgtccagct agcagacgcg ctcagcaaag aagaagtaac ggaaaatcta
    17221 gcaattgctt aaggagagag aaaaatgaga gcagtacatt ttggtgcagg aaatatcggt
    17281 cgaggattta ttggagaggt tttggcagct aatggatttg agattacttt cgtagatgtg
    17341 aatcacacga tcattgatgc tttaaatgaa agaaaagaat acgaaatcga attagcagat
    17401 gaatcaaaag aaaaaatcac tgtaaaaaat gtcaaaggaa tcaacaatca aacaaatcca
    17461 gaaaaagtaa tccaagaaat cgctgaagca gatttagtta ctaccgccat tggcccgaat
    17521 atcttacctt ttattgctga gttgattgca aaaggtatcc aagaaagaga aaaggaagga
    17581 agcacaacat ctttagatat cattgcctgt gaaaatatga ttggcggttc agcatttcta
    17641 gaaaaagaag tgtataaata tcttccggaa acatcattta ctgacaaata tatcggcttt
    17701 ccaaatgcag cagtcgatcg aatcgtccca ttacaacacc atgaagatcc tttattcgtc
    17761 caagtggaac ctttcaaaga atgggtcatt gacgatagcc aaagaaaaaa taaaaaaatc
    17821 caattaaaag gggttttata tgtagatgat ctagaaccat atatcgaacg caaactattt
    17881 agtgtcaata ctggtcatgc gactgtcgct tatacaggtg ccttgttagg ttaccagacc
    17941 attgatgaag caatgcaaga tgcgttagtt gtggcacaat taaaatcagt tttgcaggaa
    18001 acaggaagtt tgctgattgc caaatggggg tttgatgcag agcagcatca tgcgtatatt
    18061 gaaaaaatca ttcatcgctt ccaaaacaaa aatatctctg atgcgatcac acgtgtcgct
    18121 cggacaccat tacgtaagtt aggttatcaa gaaagattta cacgtccagt gagagaacta
    18181 caagaacata acttgacttg cccacatttg acggcaacaa tggggattat ttttaattac
    18241 tatgatcctg aagatgaaca aagccgtcaa ttgcatgaaa tgaagatcca tgaaaacttg
    18301 gaacaattga ttcaagaagt cacaggaatc aatgatccga aaacaatcgg gaatatcaag
    18361 caaaacgtga accgttatgc caagcaagtc gcttaaaata ggatacgaaa aaggggaatg
    18421 tgacgaaatt tttgtcacat tccccttttt cgaataacta ggctgtttgt ccttcaagat
    18481 agggcagatc caattcttta ccgtaacgtt gttctaaagc taggcggatc aaacgagctg
    18541 ccaggttctc atttcttgca aggataggtc catggaaata agaaccgaag acatttcggt
    18601 aaatgacacc ttcagattgg tcttcaccat tatttccttg accttgtacc actttcccca
    18661 aaggtcgttc accttcacct aagaaagtcc gaccattgtg gttttcaaat ccataataag
    18721 tttcattgaa ttcttcgtta tggataacga tatcaccgat aaaccggtta ttttcctgac
    18781 ttaacgtgta gtgatccagt gcactgattc cttggatctt ttctccatta gctcccatgt
    18841 agtagtgacc tagcaattgg tagccaccac aaatggctaa catgacgcca tcattttcga
    18901 tatagttgat caaagaatct ttctttttct ggatgtcttt tgaaatgatt aattgctcaa
    18961 agtcttgacc accgccaaag aaaaccaagt catatttatc agcatcaaaa ggttcatgta
    19021 tactaacgat ctccgtatgg caagaaaccc ccattttttc tgctatatat ttcaacatca
    19081 aaaggtttcc gttatcacca tatgtgttca tcaaatttcc ataaaggtgg gcgatattga
    19141 gttcataatt agccacggtt cattcctcct ttgataaatc cttgagcagc tagttcttta
    19201 cgaagctgca atacagcagt gtaagtagct aaaatataga catgctcagt tggcaattct
    19261 ttgatttttt cgattacttc tggtaattct tttgtttctg tcaatttatt ttctggaatc
    19321 ccggcaactt ttagacgtaa agtcatatct gtatgacggt ctcctccaga aataacagct
    19381 gggatatcca tatcggcaaa gttttcaaaa ttaccatccc aaatccagct gacatcgatt
    19441 ccgtctgcgt aattggcatt taataaagcc actaaagaaa atggataagg agctagacca
    19501 atcatatcga ttacttgatt gatacctaca ggatttttga caagtactaa tgtacatttt
    19561 ttcccattga tattgatgac ttcttgtcgg ccgaatactt tctcgtcata tcctaaacct
    19621 tgtttgattt tatcaggatc gacattgaag tactctgcca ctgcagtagc tgctaaagca
    19681 ttgtagacat tatacatacc gccaacttcg attccgtatt catgaccatc gatcacgaaa
    19741 tctgctgaca cattgtccat ccgtaccata tcagttaatc gataatccaa ttcaggacgt
    19801 ttgaagtcac aatttggaca gtaatatttc cctaagtttg cataagtgat cattttataa
    19861 tgcaagatgt gatgacaatt tggacataag acaccgtctg tattgtaatg agccatttgt
    19921 tcacgatctt cttcatggtc aaagccataa tattttctag gattgactgt ttcgatagaa
    19981 ttgaagattg gtgaatcacc gttactgata atcgttgcat ttggtgactt tgcggcaccg
    20041 tctacaatca ttttataggt cgtatagatt tctccatacc gatccatttg atcacggaaa
    20101 atatttgtaa ataagaacag ttctggtttc atatattctg tgactttgct caaacttgct
    20161 tcatctattt ctaggacagc aaactttttc tgtccttttt ttggttttgc ctgcaagaaa
    20221 gtcgatacaa ttccctgtac catattcgca ccagtagggt tggttagaac ttcatcgaat
    20281 tgctggcgca aaatattgac tgttaaagcg gtagtcaatg ttttaccgtt tgttccggtg
    20341 acaacgacga cttggtagtc ttttgccaaa ctatctagta tatgtggatc gactttcagc
    20401 gctagtttac ctggtaaact tgatccgcct ttaaaaaaag tttttaatgc ccattgcgac
    20461 gtttttccaa ctgcaatcgc aaaatgactg cgtattccca ttatgtaacc tccaaaaacg
    20521 atttgctgac gaataaattc aactaatcat accatatgtt gaaaaaaagg ttaaattgct
    20581 tttcttattc ttaagaaaag gttacggctg aaagtgcatg aaatcggaca aaatcgcatg
    20641 atttaacaaa aaaacagctt gaaacaaaat gattgtttca agctgctgtg attttattat
    20701 tccctcttac ctatattccc attttaaccg ataataattt tctcgcttgg atattcatag
    20761 cctagatctc gtgtttcttt tggcacgaat aacatcaatg tatatagcat tccgatccgc
    20821 ccaataaaca tcagtgtagc aatcgtgatt ttgcccacaa cagacaagtc tccggtaatc
    20881 cctaaagata aaccagttgt tccaaacgca gaagttactt cgatgatgat cgagatcagc
    20941 gtttgttctt ctgtagcaga taaaaaaacg atacaaaaga aacacatacc aagagaaagc
    21001 ataaagacaa cgactgattt tcgcacatca tcttgatcga ttctccgtcc aaaaatattg
    21061 atgttatctt cacttttgag gaaggaatat agatacaaac cgatgattgc tacagtagtt
    21121 gttcgaatcc cgccgcctac agaactagga ctgcatccga taaacatcag taaagaaaaa
    21181 atgatcagtg ttgtgatttg aaaatcaccc aaatcgtgaa tctgcagacc agcattacga
    21241 gtcgtaatcg aataaaacat cgaattgatc catttgacac tcatattgga atcttggaat
    21301 aaatggtcct tttccaatag ataaatcaag acagttcccg aaacaaacaa gataacaaaa
    21361 gctaacacag ctaatttggt aaacaaggaa aaacgaaacg gaagcttcgc attggaacgt
    21421 ttgtataata gccattcccg gcactccatc aatacaggaa aaccaattcc tccgacaaaa
    21481 atcaaaaaca tgatcaggat caagaaaaaa tagtcatgtg caaagggctt gatggaatcc
    21541 ccagtgacgt caaacccaga gttcgtgaca gccgatatcg cctgataaaa accgtaaaaa
    21601 acggcatcac gccaacgatc aaaatagcct ctgtaataaa aataaataga aaagaatgtc
    21661 ccaaaaagta attgaaacca gattaaaata gcaaaagtga tccgaatcag tcggacgata
    21721 ccagacaaac gcggttgatt catatccgtc atgatcagct gtcgctgttt cagtgtgatc
    21781 cgtcgtttag aaaaaatgac aaaagcagta gaaatcatca tgatccccaa accaccaact
    21841 tgaaataata tttccagcag tataataccg ttatcattga acacagaatt gatatcaaaa
    21901 gtcgatagtc cagtcacact cactgtactg attgccatga acagcatgtc cacaaaagaa
    21961 acatggctat ctggttcgcg aaaaatcggc atataaaata gaacgagtga taagaccgtc
    22021 atcaatatat aataaaaaac gatgatttgg atcgatgaga aatgattggc agcaaacttc
    22081 tgtcctcgcc gctgcagcct tcgaaagaat aaatcaacat gcacagtact atcctcctga
    22141 caatagtcgt ttctaccagt atacaagggg aattaggaat actcaaagaa attatcaaac
    22201 agataacaat acagctttcg attaaaatag aaatggctta taataaggaa aatcctagaa
    22261 aaaagaagga ggaggaataa caaattattt aatgctcaac aaatcgtaga aaaaatgaaa
    22321 aatcaaaaaa taaattatga tacagttctg aaaaaaatga tcatgcaatg ggagaaagaa
    22381 gaagtaaagc ctaagatatt aatacataca tgctgtgctc cttgcagtac acacacattg
    22441 gaattcatgt ctcaatatgc agagatcacg ttattttttt caaattcgaa tattcatcct
    22501 aaaagtgagt atttgcgaag attacatgaa caaaaacgat ttgtagacca atttaatgag
    22561 aaaactgacc atcatgttgc gctaatcgtt gatgaatacc gtccaaatga attcaccaaa
    22621 atggttttaa caaaccatct tgaaaacgaa aaagaaggtg gtgctcgctg cagtgcatgc
    22681 ttcaatatgc gattagatct tgttgcgcaa aaagcgcaag aactaggata cgattacttt
    22741 ggaagtgccc tgaccatctc gccaaagaaa aatgcagctt tgatcaatca gatcggaatg
    22801 gatatccaaa agatttacgg gacacaatac ttgccaagtg atttcaagaa aaacaaaggc
    22861 tatgaacgct ctttgcaaat gtgcaaagag tatgatattt atcgccaatg ttattgtggt
    22921 tgcgtgttcg ctgccaagca gcaaggatgc gatctgaaag aaatcaatcg ggaagcaaaa
    22981 gcttacttaa aaacatcaac cgtagttttt gaggaaaatt aaagaaatct ttcggaaaaa
    23041 cgtaagaaaa aaataaagaa tttatggtag aaataaggta gactgtataa tttgtccgta
    23101 gtaaagtaag gaaacaagaa taaatttcaa tgaaggaaga gataagatgc gaaaagtagc
    23161 acctattttg aagccaatcg ctgtattaac aatctcgacg attgtcgcga ctactacagg
    23221 tattgtgaat agttccagct accgtgcacc aagttcaagt tctagtactg tagaagaaac
    23281 aacaccaact acttcagtct cgacatctga accaacaaca acggaaagtt tgaatgaaac
    23341 cactacgaca agtacatggg acgatacaac aactagttcg tcgtatgatg agacatatac
    23401 aactgacagc tcaagcgaaa caagtaatac ggtaccagat ggcactccat cggattcaac
    23461 caatccaagt acaagtccgg atacaagtgc tagctccgaa acgataccaa gcagtacgac
    23521 tgtagatgat aacacgcaaa atgatgatgc agcacgtaca gcacagcaaa accaagattc
    23581 aggaaatacc caaacgtata accagcaagc aggtgattct caatgacatt tttactagac
    23641 cttatcaacg gggtgcataa attccttggc tatttagaca tcagtcctaa atatcttaac
    23701 cgtggatata cgattttaag tgtgattccc acgctttatt tattgagaat tgtttatgga
    23761 ctttggcaaa accaaaacta tcttcaattt ttcttatatg gacttgcatt tctagtgctt
    23821 gtttatttta ctgttttaaa tgtattttat tactttttag ataaaaacac gaaagccgat
    23881 gtcactcagc tttttgtgaa gtatttacct gatgaagcgt tcaacatcca gacagaagaa
    23941 tcgatagata atggaaattc gatcgataaa gtgaatacac aagaggtcat ggtttcttat
    24001 gacgaagatt atcaattgaa attagccgag aatatgcggt atttgattgg aaatggtgag
    24061 atcaaaacaa atgaactcgg tcgcatggat ggatttctgg tcgatagaaa tacattgtat
    24121 ccttattact atgtcaagaa aacaggagag aaagagtatg ttctaaatat tggacgaagc
    24181 tactcggaca tggaaaaagt agggaccatt cgacttgact caacagaaga cacattggaa
    24241 cctgtcggat tgttcatcgt cggcggtgat tttgtcaaag acgggttacg ctatcatgag
    24301 ccttatcgtc tgaaattgat tgcaaaaaag gcacagtcgc aggaagaacc agtggtttat
    24361 agtcgtagcc aaagaagaag acattcataa tgtgatgaaa cgccgtgtat cagtggttgc
    24421 gataaaaacg tttattcgga ataaggggga tgtgacacgt cttttgtcac gttccttttt
    24481 tatataacga gaaagataag acgaacacat cacttattct ttcctttcat ttataaacat
    24541 tgtagaataa agaaagtaca acgaagtatt gtgaaaaaac gtaataaata acgaggaaaa
    24601 tacaagtagg aggtaagctg tgaaagaatt tttgaaaaat tgggggattt tgatccttgt
    24661 attagcggct attttattag ctagagtgta cgtgtttaca ccagttactg taaacgggca
    24721 ttcgatggac cctacattaa gtgatggaca acgattgatt tcatctaaga tctcaaacta
    24781 tgaacgaatg gatattatta ctacaaagga accgggggat gaagaacgga tgattgttaa
    24841 acggatcatc ggtatgcctg gagatacagt caagatggaa aatgaccagt tgaccattaa
    24901 tggcaaaaag tatgatgaac cttatctgga tgagttcaaa aaagaatttt cagaagataa
    24961 gttacaagga gaatatgctt atagctcagg attccaagca caagcagaaa gttcatccac
    25021 ctttacgagt gactttgaat atactgtgcc aaaaggaaag tatcttgttc taggcgataa
    25081 ccgcttgatt tcaaaagaca gccgaatgtt tgggttagtc gacaaagata tgatccaagg
    25141 aaaagttgtt ttccgttatt ggcctctttc agaaattaaa atcatgtgat gaaaaaataa
    25201 aaagaagctg tgacatgttt tttgtcacag cttctttttc cgaaaattcc ttcttatttc
    25261 ttggagttgc tcactttttt tgcaatctca ttttaagctt tttggctgat ggataagaaa
    25321 agcgaagcgt ttttgttcat aaatagcttt tccccacgat ggaaggtatg actagtagca
    25381 gagacaaagc ccgttttttc caatcgatta ttcaattctt cttggctaaa gccattatgg
    25441 actttcggat gactaatttg ttcattcttg tcaaagtcta cgatgatcaa ttgaccgcca
    25501 ggagctaaaa tttcataaag ttttgtaaga atattctccg tatcaggaat gtgtaaaagt
    25561 acaagtgata gaaggatgag attagcttgg acagcaggaa attcgacaga agcatcagcg
    25621 tggatcgttc ggacattttt cagatctgct gcttggatct tttcttctgc cattttcagc
    25681 atagtttctg aagcatcggc aatgatcagt tctttgaatc tttccgcaag cggtaaacta
    25741 acaagcccag ttccgcctcc gtaatccagc aggacttttt ggtggctgtc gcgcggtaga
    25801 taagtagtta gttcttcgcg aataatcttg gctaatgctt gacggtcagg ggaatcataa
    25861 tggttagcga tggaatcaaa aatatttttt gtcatcaaat agctccttac gtaaaacttt
    25921 gaaattttaa cttattatag cacgtgaaaa gaaagaaagc atgctatact caattcaaaa
    25981 agggagaatc tagaaagaat atgccgatat cgtttgtaaa agatagagag gaaaaaggaa
    26041 agtgtgtccg agaaatatta ctagacttgc ctgagtggtt tgggcttcct gaatcaacgg
    26101 aaaaatatat cgaggaatca agtaaactac ctttatggtg tgaaaaaaga aaagaagaat
    26161 atttaggctt tatcactctt tcacagacaa gtgaagatac tgccgaaatc tattctattg
    26221 tatgggaata aaaaaagact atcatcacca aggattagga acaaaacttt ttaaagaagc
    26281 agaaggttac gcagcaaaac attacaaata tttgcaagtg aagactgtag acgaggggca
    26341 ctactctata tatgatcaaa ctatttgttt ctacgaatca ttaggatttt caaggttgga
    26401 agtttttcca aatttatggg atgaatggaa cccatgttta gttcttgtca aaaaattgga
    26461 acaaaagtga gcaatagatt taatactaat ctgtgcttga tgaaaattct cactgtaaaa
    26521 aatgctgaaa atcaagtata ataccatagg aacaaactgg aaggtgaaaa agagcatggc
    26581 acaactattt tttaagtatg gcgcaatgaa tagcggcaag acgatcgaga tcctaaaagt
    26641 cgcacataat tatgaagaac aaaataagcc agttgtctta atgacaagcg gtattgatac
    26701 aagagatggt ttaggcgttg tttcaagccg aatcggactg aaacgtaatg cgatgccgat
    26761 atttgaagaa acagacgtat ttgacgtaat tcagaaaatg gaaagcaaac cctattgtgt
    26821 gctgatcgat gaagcgcaat tcttaaaaaa gaaacatgtc attgctttta cgagaattgt
    26881 ggacgaattg gatattccgg ttatggcatt tggtttgaaa aatgattttc gaaacgagtt
    26941 atttgaagga tcaaaatatt tattgcttta tgcagacaaa atcgaagaaa tgaaaacaat
    27001 ctgttggttc tgccacaaaa aagcaatcat gaatttacat tatattgatg gaaaccctgt
    27061 ttatgaaggc gatcaagtgc aaattggcgg aaatgaagct tattaccccg tttgtcgaaa
    27121 acattacttt cacccatcaa tgattacaga aggagaataa gcatgtacga tcaattacaa
    27181 gcaattgaag accgttatga agagcttgga gaacttttaa gtgacccaga agtgatttct
    27241 gatacaaagc gttttatgca gctttcaaaa gaagaagcaa acacgcgcga aacagtcgaa
    27301 gtttatcgtc gttataaaga agtagtacaa ggaatcaccg atacagaaga actgcttggt
    27361 gaaaaactgg atgatgaaat ggctgaacta gcaaaagaag aattatctga attaaaaaaa
    27421 gaaaaagaag tcttagaaga aaaaatcaag atcttgcttt taccaaaaga tccaaatgac
    27481 gataaaaata tcatcatgga aatccgtgga gcagcaggcg gagacgaagc agcattattc
    27541 gctggcgatc ttttcaatat gtaccaaaag tatgctgaag cacaaggctg gaaaacagaa
    27601 gtgatggaag ctaacgttac cggaatcggt ggatataaag aagtgatcat gatgatcacc
    27661 ggagacaacg tatattcgaa attaaaatat gaaagtggtg cgcaccgcgt ccagcgtgtt
    27721 ccttcaactg aatcgcaagg gcgtatccat acttccaccg caacagttgt cgtgatgcca
    27781 gaagctgaag aagtagagat cgatattgaa gacaaagata tccgtacaga tatctatcat
    27841 gcttcaggtg ctggcggaca gcacgtcaat aaaacagcat ctgctgtacg tttgactcac
    27901 ttaccaacag ggatcgttgt tgctatgcaa gatgaacgtt ctcaaatcaa gaaccgtgaa
    27961 aaagcaatga aaatcttgcg tgctcgtgtg tacgataaga tccagcaaga agcacaaagc
    28021 gagtatgatg ccaatcgaaa atcagcagtc ggaactgggg atcgttcaga acggatccgg
    28081 acgtataatt tcccgcaaaa tcgtgtgact gatcatcgta tcggattaac tatccaaaaa
    28141 ttagatcaga ttttagcagg gaaattagat gagatcgttg atgcattgat catgtatgat
    28201 caaacatcaa aactggaagc tatgcaaaat gggtaaaatg acctatcgag aagtcctgtc
    28261 acgggcttct tcttttttag aggatcatgg gaaagaagca tatagtatcc aatttttatt
    28321 tttggaacga aaacaatgga aaaaacttga ttggctcctt catatgaacg aagagatttc
    28381 agaagaagaa cagcggttga tcgaaaccga tctgcgactt ctgcttgcag atcatccacc
    28441 tcagtatttg ctaggatatg cagattttta tgatcatcgg ttaaaggtaa ctgaagcaac
    28501 actgatccct cgaccagaaa cagaggagtt agtcgaatgg tgtttagacg agacgcctgg
    28561 tgtaccgtta gaagtgatag atattgggac agggactgga gcaattgcta ttagtttgaa
    28621 agcagcaaga aaaaattggc atatatctgc tgtggatctt tcagaagaag cattagaagt
    28681 agcgaaagaa aatgctcaga aagaaggaac gaaaatcagt ttttatcatg gagatacatt
    28741 aggaccagta atggatcagc aatttgatgt gattatttct aatccgccgt acatcagtcg
    28801 gaatgaatgg gaactgatgg atgaaagtgt ccggtcattc gaacctaaaa tggccctttt
    28861 tgctgagaac gatggattag ctatttatga aaaaatagca gttgaagcac caagcgtact
    28921 aaaatcaaat ggaaagattt ttttagaaat cggatttcgc caaggtgaag cagtaaaaaa
    28981 aatatttcag caagcatttc cagataaaaa agtggcgata aaaaaggatc tttttggcaa
    29041 tgaacgaatg atccaagttt atggttgaag ttgtggatga aaaatttttt atttgttttt
    29101 ttattataaa aaaacactta tttgacaagg atgtaaacga ctttttggtt tatcaacaag
    29161 tttatccact attgacaaat agattatcca caaacagtgg aaaacttgag gataaactca
    29221 gacaaaataa gaatgtatga aaaaggggtt gtggataaac tgtggaaacg aaacgatatg
    29281 atgaaacaga attgcaagag gcagccgaag cactgaaaga aggagaactt gttgcttttc
    29341 ctaccgaaac agtatacgga ttgggcgcca acgctctttt accaaacgct gtcaagaaag
    29401 tgttttctgt aaaagggaga ccgcaagata atccattaat cgtccatgtc gcctcttttg
    29461 aacaagtaaa agagtatgtg gacaactttc atccggcagc agagaagatt gtgaagaact
    29521 tctggcctgg accattaact ttgatattta agatcaaaaa agacactttg ccctcagttg
    29581 tgacgggagg attatccaca gctgcatttc gtataccgga taacaaaaaa acactagaag
    29641 taatcgaact ttccggtgtt ccgcttgtcg gtccaagtgc aaatacgtcg ggaaaaccaa
    29701 gtccaacgac tgcagatcat gtatatcatg atctacaagg aaaaattacc gggattattg
    29761 atgatggagc tacgcgaatt ggtgtagaat ccactgttct tgatttaagt gatccaacag
    29821 ccatgcctat gattttacga ccaggtgcag taacgaaaga acaaatcgaa gcagtcatcg
    29881 aatctcctgt tgctattgat cagcatcttg taaaagaaaa tgaaacacca aaagcccctg
    29941 ggatgaaata caaacactac tcacccgata cacgtgttct gatggtcaga gatggcgatt
    30001 ggtcaactgc agttcaatgg gcaaaaaata agaagatccg tgcaggtgtc atagcaagcc
    30061 ccgaaattgc ggatcaagtg cggacagata ctgcagctgt ttatatgtat aacgacaact
    30121 cagtagaagc ggcggctaaa ggattgtttg caggtctaag aggattagat gaaccaacac
    30181 ttggattaga tttgattttt gtacaagtgt atccagaaac tggattgggg aatgcttaca
    30241 tgaatcgctt gaaaaaagca gcaggacaaa attattttga aaaatgatca attggttatt
    30301 gtcgcattct tttagtatga tacaatgcta tcaagtaaat cttctatcag tgaacgaaaa
    30361 actaagcgta actaatcgta atagaagaga tacgaatatt tggcaatttg tttttgatgg
    30421 gaaaaataaa attgtaggaa aataaaaagg agctgttgtt tgtggtagat tacaaaacgt
    30481 ttgaccctga tctttgggct gcgatcgcca aagaagaaga aagacaagaa cataatttgg
    30541 agctgattgc ctctgaaaac tttgtctccg aagcagtgat ggctgcacaa ggaagtatct
    30601 tgacaaataa atacgcagaa ggttatccag ggcatcgcta ttatggtggg tgtgaatttg
    30661 tcgatatcgt tgaaaattta gcgattgacc gtgcaaaaga attattcgga gcgaaatttg
    30721 cgaacgtcca gcctcactcc ggctctcaag ccaacacggc tgcttatctc gctttggtag
    30781 aaccagggga cacgatctta ggaatggatc tttccgcagg cggacatcta acacatggat
    30841 caccagtcaa cttcagtggc aaaacctatc actttgttgc ttacggtgtt gatccgacaa
    30901 cagaagttat tgattataat gtggtacgta ttttagctag aaaacatcaa ccaaaattga
    30961 tcgtagcagg tgccagtgct tacggacgaa cgatcgactt tgcgaaattc agagaaatcg
    31021 cagatgaagt aggcgcaaaa ctgatggtag atatggcaca tatcgcagga ttagtagcag
    31081 caggacttca tcctaatcca gttccttatg cagatatcac aacgactacc actcataaaa
    31141 cattgcgtgg ccctcgaggc ggcatgattt tgacaaacga tgaagcatta gcaaaaaaaa
    31201 taaatagtgc ggtatttcct ggtattcaag gcggccctct agagcatgtg attgcgggta
    31261 aagcagtagc attcaaagaa gcattagatc ctgcatttaa agaatatagt gaacaaatca
    31321 tcgccaatgc aaaagcaatg gtcaaagttt tcaatcaagc aattggaacc agagtcattt
    31381 caggggcgac agataatcat ctgatgttga tcgatgttcg cgagttaggt ataaatggaa
    31441 aagaagcaga gagcattttg gacagtgtga atatcactgt aaataaaaac tcgattcctt
    31501 ttgaaacact aagtccattc aaaacaagcg gtattcgaat cggcacgcca gcaatcacta
    31561 ctcgcgggtt caaagaagaa gatgctgtaa aagtggctga actagttgtc aaagcattac
    31621 aagcaaaaga tgataacgct caactagacg aagtcaaaac aggtgtacgc gaattaactg
    31681 aaaaatttcc gttgcataaa aaataaaaat ttaaattcca ttagtaaaca gaaaagttca
    31741 atgttgggct tttctgttta ttttttggga aaacggattc tttgacaata tcggtgatgc
    31801 tctctagtat atgaggtgta attttagtct tcacactaaa tctcagggag gaaaagtcat
    31861 gactgatcgt atctcgttag aaaaggaagc agtagcattc agtgatgcaa atgcgcctca
    31921 tccgcgtatc tatgaactag caccggaaga aggaagagtt ttactagaag aagtacaaga
    31981 atcacctgtg aacaaatatt ccgtcgatat tgaagacttg atggtggata ctggcgaatg
    32041 gggaaaactc aatattcgtc tcgtacgacc agaagggaat atggataaat taccagttat
    32101 tttttatatt catggagcag gctgggtttt tggcagtgct caaacccatg ataaattgat
    32161 cagagaactt gcggttcgta cgaattccgt cgttgtcttt ccagaatata gtcgatcacc
    32221 agaagcaaaa tatccaacag caattgaaca aaattatgct gtgttgcaac agctgaataa
    32281 attagccaag tcaaaaaatc tggatctcga gaatctaatc gttgcaggag attcagtagg
    32341 tggtaacatg gctacagtca tgacgatctt aacaaaagaa cgaaagggcc tcccaatatc
    32401 caagcaattg ctgtattatc cagtcacaaa cgctgatttt gatacagatt cctatcatga
    32461 attcggagaa aactattttt tgacaagaga aggaatgatg tggttttggg accaatatac
    32521 gacgaatgaa gaagagcgtg ctgaaatcac agcttcgcct ttgagagcaa atataaatga
    32581 actaaatgat cttccttcag caatgatttt aacgggagaa gcggatgtat taagagatga
    32641 aggtgaggct tatgcgcgca aacttcgtga tgcaggggtt cctgttacac aagtacgctt
    32701 ccaaggaatc atccatgatt ttgtcatggt aaatgctatg gatcagacaa aggcaacgcg
    32761 tgcagcaatg gcattatcta cttcttggat caagaaaaaa gaataagctt tgcttgtccg
    32821 caggaaaact tcttttcaaa aacggatttt cttaggaaaa atggcgagtt tgactagtca
    32881 atcacttgat tttgttttac aattaaaaag aaacgacaga acaaaggaga gcttaaaaaa
    32941 tgggcaaatt tcaagtgatc gatcatccat tgattcaaca caaactaact attattcggg
    33001 acaaaaactg cggaacaaag gtttttcgtg aagtagtcga tgaaatcgct atgttgatgg
    33061 catatgaagt atcacgggat atgccattgg aagacatcgt gatcgaaaca ccgatcactg
    33121 aaacaacaca aaaaacgttg tctggtaaaa aagtagcgat tattccaatc ttgcgcgcag
    33181 gtattggaat ggttgacggt atcttggaat tgattccagc tgctaaagtg ggacatatcg
    33241 gtctttatcg agatgaagaa acattggaac cacatgaata tttcgtcaaa cttccagaag
    33301 acattgatgc acgtcagttg tttgtagtag atccaatgtt ggcaacaggc ggatcagcaa
    33361 tcatggcaat cgatgcattg aaagaacgtg gcgcgtcgaa cattaaattt gtttgtttgg
    33421 tagcagcacc tgagggagta aaagctttgc aagaagcgca tcctgatatt gacatctata
    33481 cagcttctct agatgaaaaa ttgaatgaac atggttatat cgttcctgga ctaggggatg
    33541 cgggtgaccg tttgtttggt acaaaataag taaatacgaa aaagggtgtg acacaacttt
    33601 tgtcacatcc ttttttggtc atttttaacg tttgatgcag aacagctttt tcacagcttt
    33661 cgtttgcata taaaaaaacc atcccaaaaa tgcagagatg gtcaaattca aatctttttt
    33721 agttctttgt agttaacgat tactacaccc ttactttgcg tcatcaagtt cgcattttct
    33781 gcagtttcat caatctcaac aacagcggaa tttttcaatt gctttgaaat cgttccagtt
    33841 tgcgacttgc cgtgaattgt gaacattacg tgagtattga tcttgaattt ttcaccaatt
    33901 tccgatggta cgatagttgt atcaaatttt ccaaaagttg ccattttcat aaaacctgcc
    33961 tttcacatca attataccac gttttatgaa aaatatcatg aaattaaact aattttccat
    34021 cggactcttt acaatcagcc aaatagagta tataatttct tttggataag gccagcttag
    34081 ctcagttggt agagcaacgc actcgtaacg cgtaggtcgt aggttcgatc cctatagctg
    34141 gcattaaaag agaagacaga tatatcaagg atttttaatc cattgataca tctgtctttt
    34201 tgtttaaagg aaataaagta tgctttctta gcaatagagc atgtattatt tctataaaaa
    34261 tttaggagaa taaaacgact agcaatatag ctgtgaaatc aaatatcaca tgaactgccc
    34321 aacttgtaat gatcgagttg cttttaatgg cagcttggtt gaataacaat cttgccaccc
    34381 cttgtatcaa aaggatgtgt gctacagtgt gtaaaatatt tccattatca taagtactgt
    34441 aatggataaa tccaaagatg attgctgaca agaaactagc gacaggaatg ctgaacttac
    34501 tagaaaaaat agcgagaaaa tacactgaga acaattcttc tccaagtatc atgataggca
    34561 aaataataaa taataacggg ctgaaagcct catttattgg attgcctgtt aaaccccatt
    34621 tcaaaatttg ttgcaaaaat accgagactg cggcactgat tactacattg ataaaaaaat
    34681 atttggctat atttttgaca ggagcgacag gtttcgagaa catttttttc gtatcttttt
    34741 taccaaaaac aagtgtaaat gctataaatc cagtgatagt taaagaaaaa atgctaataa
    34801 tggatggcgc aaatagcaac cctaacaaac cgagtacaac gacaatagtg cccaatatcc
    34861 cttttttaag ttctattttt tttcctaaaa tgttattcat gataataact cctactattc
    34921 agtttttgaa gatagagtca gtatacatga agagttaaaa taggcaatgt ttttttatgg
    34981 atatttgtat tgctaaaaat ttatcttata tattcatttt gattatacta cttttatttg
    35041 taaaaatttt ctagcaaaac caagtgcttg caactgatta agcgtacaat tttttagatg
    35101 ttccgagcgt acttcaatca tttcaaagga gttgctactt aaatcgatat tttttaaatc
    35161 agtatcaaaa aagctagcat tttctaaatc attagtagaa aacattattt tagtgaggga
    35221 acagtctaca aaatctgcgc ttgataagac agagtgctca aaggtacttt cttttatgtt
    35281 tgaaccagat aaatttacat agtccatttt acaattctcg aataacgtgt tcccaatata
    35341 actttccatc aatttagtac ctgttaattt acaattgaca aatttcacgc gatgcaacat
    35401 gctttttgtc aatatacagc ctgaaaaatc acagttttcg aatatacagt cggtaatctc
    35461 cattctttga aaatcattgg aagcaaaaaa tgcatacttg aaaatagatt tgtaaataat
    35521 tggatggcag attatttggt tttcgatgac ctctttttgt gaaaggatat tatacagttc
    35581 aaaatcttcg ttttcataga tatgaaaaaa ggatccttta ttcaagcttg cttcattaac
    35641 tttaggaaaa atcatattta attacctcca ttttcataaa gtcatattaa caaaagctaa
    35701 accaacttac attagcagaa aatgagatag gttttcgcct ttttcgataa cgatagtgtc
    35761 gctatctctt gaaacgttct tagaattgcc ctgagagaca caaattaggc gtaattctaa
    35821 taaaaatctt agaataaaaa tttttactga tttaatttag aatgttttta aaataaaaat
    35881 cgttgccata acagtgtatt gaaaggtttt aacaatccag taatgattta aaaaaatcta
    35941 gatgtagcgt atactttgtt tatagaatgt agtgggaaga aatatatttt tgggaggaaa
    36001 tcgtgatgtc taaaagtgaa gaaatagaaa acatggtact aaaattatat gatctcgttt
    36061 taaatccaga gatcaaagaa aaggaacgta tacttttgat agacgcaaag acaggcttag
    36121 aaaaaggtca gtattatcct aaagtcataa ataatttgga acgtagttta cgtccgttag
    36181 caatcagggg agaattgtct aaaccagtat caccgtttta tatggagata tcaacaatag
    36241 gaaaatttga aaaagaatta ggtcgaggaa tggcttcggc accgattact tttgggcatt
    36301 tataaaaacg agttattcat ctcaatgaat taaaaagtat agtcaatctc ataatgcagg
    36361 ctaggttcat ttatttgaac agagtctgta tttttttatt ctaaataaag aaacagatgt
    36421 ttctttatat tgtattttat cctttaatta acacaaaaac agctagtata aactaataat
    36481 gttaattaaa agtgtatttt atgaaactat cgttatttat taatgttgca tttttgt
//
LOCUS       DAIGTA010000025        33962 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.025, whole genome shotgun sequence.
ACCESSION   DAIGTA010000025 DAIGTA010000000
VERSION     DAIGTA010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.025"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..383)
                     /locus_tag="NOB43_001306"
     CDS             complement(<1..383)
                     /locus_tag="NOB43_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HCI0982174.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVI"
     gene            complement(497..1081)
                     /locus_tag="NOB43_001307"
     CDS             complement(497..1081)
                     /locus_tag="NOB43_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HCI0982175.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(1208..1639)
                     /locus_tag="NOB43_001308"
     CDS             complement(1208..1639)
                     /locus_tag="NOB43_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI0982176.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(1657..1977)
                     /locus_tag="NOB43_001309"
     CDS             complement(1657..1977)
                     /locus_tag="NOB43_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0982177.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENK"
     gene            2277..2417
                     /locus_tag="NOB43_001310"
     CDS             2277..2417
                     /locus_tag="NOB43_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982178.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            2715..2972
                     /locus_tag="NOB43_001311"
     CDS             2715..2972
                     /locus_tag="NOB43_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HCI0982179.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(2943..3251)
                     /locus_tag="NOB43_001312"
     CDS             complement(2943..3251)
                     /locus_tag="NOB43_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982180.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            3329..4075
                     /locus_tag="NOB43_001313"
     CDS             3329..4075
                     /locus_tag="NOB43_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HCI0982181.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            4090..4293
                     /locus_tag="NOB43_001314"
     CDS             4090..4293
                     /locus_tag="NOB43_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982182.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            4309..4647
                     /locus_tag="NOB43_001315"
     CDS             4309..4647
                     /locus_tag="NOB43_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HCI0982183.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            4634..4804
                     /locus_tag="NOB43_001316"
     CDS             4634..4804
                     /locus_tag="NOB43_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982184.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            complement(4902..5567)
                     /locus_tag="NOB43_001317"
     CDS             complement(4902..5567)
                     /locus_tag="NOB43_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982185.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDHLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            5622..6320
                     /locus_tag="NOB43_001318"
     CDS             5622..6320
                     /locus_tag="NOB43_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HCI0982186.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFSEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDTVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            6498..6838
                     /locus_tag="NOB43_001319"
                     /pseudo
     CDS             6498..6838
                     /locus_tag="NOB43_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6831..7502
                     /locus_tag="NOB43_001320"
     CDS             6831..7502
                     /locus_tag="NOB43_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCI0982187.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            7508..8194
                     /locus_tag="NOB43_001321"
     CDS             7508..8194
                     /locus_tag="NOB43_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982188.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFKNKYQIKGIKLSH
                     ETIKKLRIGG"
     gene            8197..9027
                     /locus_tag="NOB43_001322"
     CDS             8197..9027
                     /locus_tag="NOB43_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HCI0982189.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLGSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSNEHLRLAKKLQSNLTEDFPKEMTKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            9044..9895
                     /locus_tag="NOB43_001323"
     CDS             9044..9895
                     /locus_tag="NOB43_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0982190.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            9892..10251
                     /locus_tag="NOB43_001324"
     CDS             9892..10251
                     /locus_tag="NOB43_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCI0982191.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVIDVKGMQTKDFKIKAKLFCHKYQV
                     PLILAKKYRNTFKEERF"
     gene            10266..10427
                     /locus_tag="NOB43_001325"
     CDS             10266..10427
                     /locus_tag="NOB43_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI0982192.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIVNL
                     RREIRRLEE"
     gene            10430..10729
                     /locus_tag="NOB43_001326"
     CDS             10430..10729
                     /locus_tag="NOB43_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982193.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVAEVQKIGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            10729..11046
                     /locus_tag="NOB43_001327"
     CDS             10729..11046
                     /locus_tag="NOB43_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HCI0982194.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLYQDRFKFVEKYREILDEYME
                     EAE"
     gene            11043..11246
                     /locus_tag="NOB43_001328"
     CDS             11043..11246
                     /locus_tag="NOB43_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HCI0982195.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASETIRKFGISILNDDRKWEAER"
     gene            11243..11536
                     /locus_tag="NOB43_001329"
     CDS             11243..11536
                     /locus_tag="NOB43_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982196.1"
                     /translation="MKLKDGFYTDAYGIGGLMMDLPTKNPIKQEESEIKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVVRLVDMEVIKS"
     gene            11566..12006
                     /locus_tag="NOB43_001330"
     CDS             11566..12006
                     /locus_tag="NOB43_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0982197.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            12081..12548
                     /locus_tag="NOB43_001331"
     CDS             12081..12548
                     /locus_tag="NOB43_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HCI0982198.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(12948..13301)
                     /locus_tag="NOB43_001332"
     CDS             complement(12948..13301)
                     /locus_tag="NOB43_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982199.1"
                     /translation="MAKIDDYRSDMIEYIELFAKNSNNNIIIQTGGATICGTPIDFDA
                     EVKVNPLIDAMMDSFAEFRSKKIDDIEKDDEQSLVVKSIFLKDVTIIGERTTNIPFLV
                     VFADQISAISLGNLE"
     gene            14019..14090
                     /locus_tag="NOB43_001333"
     tRNA            14019..14090
                     /locus_tag="NOB43_001333"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14052..14054,aa:Lys,seq:ttt)
     gene            14230..14397
                     /locus_tag="NOB43_001334"
     CDS             14230..14397
                     /locus_tag="NOB43_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982200.1"
                     /translation="MYRPQYLEQKHEVITVQNGNGEIVRKYRRPIKSNTYKRKESNEV
                     IPLYGKRIAKY"
     gene            14423..14767
                     /locus_tag="NOB43_001335"
     CDS             14423..14767
                     /locus_tag="NOB43_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCI0982201.1"
                     /translation="MTEEFYRWLLQLIREDCLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            14772..15053
                     /locus_tag="NOB43_001336"
     CDS             14772..15053
                     /locus_tag="NOB43_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982202.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNIFGYSIEEINYYIDFAEAFIPMVR"
     gene            15156..15470
                     /locus_tag="NOB43_001337"
     CDS             15156..15470
                     /locus_tag="NOB43_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HCI0982203.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            15448..17142
                     /locus_tag="NOB43_001338"
     CDS             15448..17142
                     /locus_tag="NOB43_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCI0982204.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            17162..18340
                     /locus_tag="NOB43_001339"
     CDS             17162..18340
                     /locus_tag="NOB43_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI0982205.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKDFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            18303..18989
                     /locus_tag="NOB43_001340"
     CDS             18303..18989
                     /locus_tag="NOB43_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HCI0982206.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            18989..20149
                     /locus_tag="NOB43_001341"
     CDS             18989..20149
                     /locus_tag="NOB43_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI0982207.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            20159..21034
                     /locus_tag="NOB43_001342"
     CDS             20159..21034
                     /locus_tag="NOB43_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982208.1"
                     /translation="MKYILCQLAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            21031..21342
                     /locus_tag="NOB43_001343"
     CDS             21031..21342
                     /locus_tag="NOB43_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982209.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            21332..21685
                     /locus_tag="NOB43_001344"
     CDS             21332..21685
                     /locus_tag="NOB43_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCI0982210.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            21675..22076
                     /locus_tag="NOB43_001345"
     CDS             21675..22076
                     /locus_tag="NOB43_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982211.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            22069..22473
                     /locus_tag="NOB43_001346"
     CDS             22069..22473
                     /locus_tag="NOB43_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982212.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            22485..23093
                     /locus_tag="NOB43_001347"
     CDS             22485..23093
                     /locus_tag="NOB43_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0982213.1"
                     /translation="MAKTKTVVTTFDNISIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELEAKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            23113..23475
                     /locus_tag="NOB43_001348"
     CDS             23113..23475
                     /locus_tag="NOB43_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982214.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            23478..23660
                     /locus_tag="NOB43_001349"
     CDS             23478..23660
                     /locus_tag="NOB43_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982215.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            23677..27096
                     /locus_tag="NOB43_001350"
     CDS             23677..27096
                     /locus_tag="NOB43_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCI0982216.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNDIDKTSKALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     VTAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFIDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWSSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            27147..27884
                     /locus_tag="NOB43_001351"
     CDS             27147..27884
                     /locus_tag="NOB43_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0982217.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFTLNDYVFSFEGLVVGTDIVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            27894..30185
                     /locus_tag="NOB43_001352"
     CDS             27894..30185
                     /locus_tag="NOB43_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0982218.1"
                     /translation="MIDNLLTIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREVA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNVGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            30209..32386
                     /locus_tag="NOB43_001353"
     CDS             30209..32386
                     /locus_tag="NOB43_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982219.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPYLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAETKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYSGNPNLMANINADSFS
                     QGSGALSVVDDGDEVVITLDPNHKLEVLKPKSQPALLTGKTYTVSVEIMLEGDFTGDP
                     SKIGLRYIKMPNWVSELYTRNTLTATKGVWQKLTGTVKITAASDNAESWLIMLQNKDA
                     NNSLSGKLRLRHAKLEEGSTATPYQPNLLAEPYNMCREYPNENIADPKVKFPIKSGDH
                     QIYQGYMEEDLMIGQTYTITLKGTKPASQTFVAYNHWTVRLGELKPVDGLTDVWSLTF
                     TPTNVAAMPKLFRVYQYPQSTVGACQIDWLKIEKGNTRTPNISEYKYRGTGMRDSNNP
                     KDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTAKDA
                     QTKANANATAIDERINDTATTAFYGAQGEVSNKTKVAEYGVGTGYTTTAVGETHFERQ
                     SNGYVKCLKAGKYSISAQIRVQLGGKYASWLYTDLYKDGTSVDNLVSYGVDALQNRFA
                     ASGNIVTDLEVNDVLNMRTEIGVADGILQFTSCRTLVLTRLSD"
     gene            32464..32706
                     /locus_tag="NOB43_001354"
     CDS             32464..32706
                     /locus_tag="NOB43_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HCI0982220.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYELLREKAESAKDRADQAYSIA
                     LNNAEDIKEMKANNKWSWGYMIGLGVTIIGYFLTKL"
     gene            32722..32919
                     /locus_tag="NOB43_001355"
     CDS             32722..32919
                     /locus_tag="NOB43_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI0982221.1"
                     /translation="MILPDKYYQVIKWAVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            32930..33949
                     /locus_tag="NOB43_001356"
     CDS             32930..33949
                     /locus_tag="NOB43_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCI0982222.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHNKATFEKNYKAYVELARDSAKKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYGTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
BASE COUNT        12066 a         5214 c         6925 g         9757 t
ORIGIN      
        1 ttaataacgg tggattttac atggtctttc gcatacttat ttaaaaagcg ttgatatcca
       61 actctatcta aatcagaaat caataccgct ggcatatatt tctttatgtt cattaacgta
      121 tcttcgtatt ttctataagt gataggagat actgttcctt ctttataaag ttgcatccaa
      181 tcctcaaagt aatctgataa taatagattt ttgcgatccc ctttaaggcc tttgttcaag
      241 ttatattcta attcgttggc ggcatctttt gcttcgcctt ttgtcttaaa tcctgatttt
      301 cttatcttcg tgtattttcc gtcatctttt ttgtatgaaa tttcgtattg ccaactattt
      361 ccacgtttga ctaatcttgc cataattgaa tctactctct ttctctgata caataggcac
      421 tataaagaag cctactgtat aggtttgttt ttcttagaac acgcttgctt tggacggtgg
      481 gcgtgttttt tatttattat acagttgctt taaaaatagc tgctttttca aatgatacta
      541 aaggagagaa gtggatttct atttctccct tttggtttaa cgtgaaatga gcagttacat
      601 ccatttgttt tcctggagca acagatccca ttgtattttc gttggcatat gtctctgatt
      661 ttttgtcatc tggtccatat acttccacat ctgtacctac agggatatct gaatcgccat
      721 cattttttac ggtataagta atttttacta cttgtgcagg ttggttttct tcaaattgat
      781 ttctttcatc agttagttct acactattta gtgtatattc agcatcacca acttttacag
      841 tgtcaccaat cttatagaag gtatcgcttt tttcttcttt agaagatgaa gcagaggttg
      901 aagatttagt tactttttcg ccaccattat cacttgcttt attactatct gatccaccat
      961 ttaaagcaga accaataatt ataattaaaa ttactgctaa tacccaaaac catacttttt
     1021 tgtaaaaagg tttactaact ttatacattt ttccgtcttg acccataact ttttttgcca
     1081 tttaaatatt cctcacttct tgttataata tatttgcgat ctcagaaatg aggtatgagt
     1141 ccgtgtgcca gcacgggctt ttttaatgtt ttgctgaaat cggttttttt aataattctt
     1201 gatgtattca tacatattgc cttgcgtaag aatatttttt cttaaaatag cattggcaga
     1261 cagcataaca agtgtatctg agcttattct gaatagaata atactccata aatttttcga
     1321 gattaaactg agattcatca gtcagttcgt tctcaatata gatatttaat aaaattagaa
     1381 tagctatttt atctgcttct gtttcaaatt ttgagtgaaa agttgtagaa gtatcgtaca
     1441 aaactgaaaa ttcaaaatga gaggcgctga aatgtgcaag ttcatgagat aaatgaaagg
     1501 cttctgcagt ttcaccgtat agattttcat tcaaaaaaat gattctgggt tttggatagt
     1561 agaaaccagg ctctttcatt tccatataaa ctactttcaa attgtattcg ctcaacattt
     1621 ctttcaattt caaatacata taaaccatca ctccaactat ttgttttctt ctaaagcttt
     1681 agcaattgca atcgctttac gcattgtctc cttagatatt tcttttccgt caaaagaaaa
     1741 tacagtatcg ttttctgata aatccacatg tttaggggtt tctctttctt ctctacctag
     1801 aaggtagtct acagagactc caaagtaatc agctaaccga gctaactcaa tagaattagg
     1861 agtttgtctt ttccaacttc ctaaatatcc attcgaatac ccgaaattca tttcgagctg
     1921 tctaatggat aatccttttt cttttgctaa ctcctttatt atttcgtaag tattcattga
     1981 taaatcaacc tttctgaatg cttacaaaaa aagtttagat aaataatgta aaaatagttg
     2041 acttatatac attattaatc tatactatgt tttgtaaaca agtttaacaa ctaaaaagac
     2101 aacaaaaaat actattgatt aataaatgcc aaccgccaag aaagcttttt aaatcaaagt
     2161 ttatatgtct tatttaacta tgcatttagt atagattatt aatctaataa agtcaacgca
     2221 gttttttaaa aagttgttaa atttgtttac gaatataaaa gaaaggagag aagaatatgg
     2281 aaaaaacagt ctcggcaaaa atcgaagatt tgaaattaga catactgaaa caagcaaaag
     2341 tggcgatgga acacgcggta gataaagaag actctgccat ggttgcagcc atagcagaga
     2401 ttttagctca cgtttagtca tcgtttttac ggtcttctgg aagctgacca tagataacag
     2461 cataatgaat atctaaataa gcttgaacaa tttcttttgg cgaaattgat tcgcctttag
     2521 tagatacttg tgattcgtga tttagccatg caacaactaa atccgcagcg atttcaaacg
     2581 gcgttacact ttgtgtcagt tgccataaag aatttcacaa tatgtatggt cgtggtaata
     2641 ataccaaaga gcaatttgag gaatttatgg aaattaaaaa atacaaaaaa tcatttatta
     2701 aaggaggcta aacaatgaac aaggaaatga gccaaacaat caaggtacaa aaaatgatag
     2761 atgatctaac acatggaatt gatagccaag ccgataaaat catcaaggaa ttgcaaggac
     2821 aaaaagttaa ggatgcaaaa atgcttctca agactatcaa ctttgaaatg aatccaacaa
     2881 aaagaaagct cgccgatgtg ttggaagaaa agttggcttc cgctatcaac gagcaagaat
     2941 tactatttga aaccgatact tttaacagct gatgttttat agatgacagt ttcatccgaa
     3001 tctatatcat cgccgagaga aaagaatgtt gcttttgaca aaaagccgat aagacctaca
     3061 agcggtcttg atgttgcaag agtagatacc ccaatatcac cttgcaaggt attcacgtaa
     3121 atttgagaag aatagaacat tccatctttt tcttcgatat ttgacgcatc atcgtatcca
     3181 acgaccaaag tatcggcaaa tattttgatt ttttctccat caagcatagt aattacaaat
     3241 tctggtttca taaattttca cctccttaac aattatttca gcctgtcaca ctgataagga
     3301 aattatacca aagaaaggaa tgagaaatat gaatacacca caaattttta atttcgagca
     3361 aaacgaagtt cgaactattt tagtaaatga tgaaccatat tttgtaggaa aagatgtagc
     3421 agacgttcta ggatattcga atccgcaaaa agctattcga gatcatgtgg acttggagga
     3481 taagacgcag aacgattcgt tcaccgtcaa tggaacagca gttgttttga ttaacgagtc
     3541 aggcctttac agtttaatct taaaatcaaa acttccctct gccaaaaaat ttaaacgttg
     3601 ggtaacgagt gaagtccttc caacaattag aaaaacaggt agctattcaa acgtacctca
     3661 aagttttgca caagcattgc gtttagcagc ggatttagaa gaaaagaacc aattactcga
     3721 acaacaaatt gccgagtacg aaccaaagat tagctactta gatacgattc tttcatcgac
     3781 agatacggta gctacttctc aaattgcagc tgattacgga atgtcggcaa ttgctctaaa
     3841 caaattgcta aacgagttag gtgttcagca taaagttagc ggacaatgga tactttaccg
     3901 aaaacatatg aaccaaggat acacaaaatc gcacacaagt gagataccga aagccgatgg
     3961 cggcactaaa gttgtaatga ataccaaatg gacacagaaa gggcgagtgt ttatttacaa
     4021 cttattaatc gcagagggct attaccctca aatggattta gaggaaattg gttagaaagg
     4081 agttttagta tgactgacat tgcagaaatc actcaacgag atagagaaaa aatcaaagaa
     4141 tatgtcgaaa gttcgaagtt cttaacttac accatgcttg ctgaaagatt tggaattagc
     4201 aaaagctact tatctttaat tttaaacggt aaaaagactt ctgcagaagc aaatagaatc
     4261 atagattcga ttattactat gtacgaattg taaagggagg aacagctaat gcaatatcta
     4321 gaagcgaaaa tcccagttcc agaaggctat gtaattatct cccaagtgga ttatgaggag
     4381 ttaaaaaaag ctgatgatac tggtagatgg atgacgttgc cagaagtgct agaacggatt
     4441 aacagaaaat atgattggtt tacttctaga gttttaaaga acccaagata tagaaatatt
     4501 atcgatatcg aaaaaaataa aaatggattt gtctattatc cagttgaagg aagagacaca
     4561 tatctatttt taagaagtaa aacacttgaa tttttagaaa caaatttttc ggaaatctta
     4621 aggaggcaag cggatgggaa aatttaatag agcgctagta ttcagcgcac cgctaatcat
     4681 ctacgcttta ggactttggg gaagcagaca agcgttgata ggaacgattg tttacatggt
     4741 ttggattttt atggggctgg atgaagctga gtacaaaaca aaaaagccag tcgggaggga
     4801 ctgactaatg aaaaaaagtt taatgactat aaacgaaaaa caattgaaag aaaattttaa
     4861 tgatctcatc aaagaatttg taaaagaaac tggagaattt cctaatcaaa ttcatctagt
     4921 tgcggagggg catagccagt atcaagctgt gaaatttgag atgaagaaac aaatctattg
     4981 aatttagcag tacctctact tgtaagaaca tttattgtaa tgtttttttc gactaaagat
     5041 tcatcgtatc taaaaaccaa cgtagtaatt tttgactcat acggtggaat ggtaataggt
     5101 aatgacaacg gaggaaattt tgatagatca gcaccttttt ttaaagattt accagaatac
     5161 gcacgtatac catgtggaag ttcgtcatac attgatttta ccgttacaga ataattatca
     5221 ccaatcattg taaaagcatt taaatgatca ggaattccag aaatcgaaaa ctcaataatt
     5281 gtaacaggta aagaactgtt atttgttaac aatacagaat ctataatcct gaatttattt
     5341 tgatggtaaa catctggttt ggaatcactt tctctatcta tcaaccattc ttcgcattca
     5401 gcgaagaaat ccaattttaa attaaatttt ttgttttttc tatctgtata ggagatataa
     5461 aaagcaaatg ttgaaaatac tagagacgta ataggcaaaa taaaatcttt aatggtttta
     5521 acaatgttat tccagtcaaa ttgtttaata aagtcaataa gactcaattt ataccaccac
     5581 cattttttat ctacattata tcaaagagga gagaagaaat aatgcaagaa ttagtaattt
     5641 tgaaaaataa agaagctgtg actacgagtt tgcaagttgc agaaagtttt gagaaaaagc
     5701 atcaacatgt tttaagagat attgatgcac tgaaaaaaga tgtgtccaat tttggacaga
     5761 tgttttctga aggtaatgaa ccagattcat acggcagaaa tcgacgagtt ttcttcatta
     5821 gtagagatgg ttttttcttg ttggctatgg gttttacagg aaagaaagct atttacttca
     5881 aacaaaaata cattgaagca ttcaacgaaa tggaagatgt tattcgcaag aatactgttc
     5941 ctcaaacaat tgaagatatg atgatctacc aactagaaga aatgaaagat gttaaaaaag
     6001 atgtttccat gcttaaagat actatgcgaa ttagtgggca acaagagttt gaaattaaac
     6061 aaaaaggaaa tataaaagtt atggaagttc tagggggtaa agaaagccga gcttatgaag
     6121 aaatcagcaa aaaagtattc tcaaaatttt ggtctgaatt taaacgtacc ttttcaatcc
     6181 caagatatgg cgagttacct cgtaagagat tcgatgatac tgtttcattt attgaaatgt
     6241 ggttaccaga aactgcgatc cgcatggaaa tcgatcaact gaacagacaa caaagacttt
     6301 tcggtgatga aaatgaatag agctgaagcg ctaagaatcg ggacggtaat tgctaatcgc
     6361 tggtggagac acaataaacc aatcatccta agccaacaac atattgacaa gcaaaaagca
     6421 tggcaacaaa taaaaaagtg actccgccgg caagcaaaga gtcacaaaga aaacacatca
     6481 taaggagatt ttagcatatg gaaaaagaac tttccactct agatcaatat ttgactgatc
     6541 ctagttgggg caaatcgaat atcaaggaaa caaataatcg aaaaatcaga cgaaatcttt
     6601 tgacggatga agaactagca tgtgatcaag acgatttggg aaattttgtg agtatttggg
     6661 atcatgtcta tcttatccat ttatcgagga agtccaaaaa cctgaatata tctatgtcat
     6721 cgaagatggc ttgattgatg cgctagaaga gtatgacaga gataacttga ttgatatctc
     6781 ttattacgga tcaggtaaga aatacattgc tgaaatggag gcagaatttg atgagtgaaa
     6841 acaaagggac aacgactttt gaaaaacttt ttagtcgcaa gttaaataaa atactcaaga
     6901 aaaaaggaaa ttttgattat ttatcttggg ctcacgcatg ggagattatg aaaaagaatg
     6961 atccacaggc aacggtaact attaatgagt ataaacacta cagagttgtt tctggaactc
     7021 atcaagactt tcttgttgag gaatataaac cttttcttat ggatgaaact gggacttatg
     7081 tatctgtctc agtaacggtt aaaggacaca cggaaaccga attatttcct gttttagatt
     7141 atcgaaacca accagttgtt aaaccaaatg caatgcaaat caataactca ttgaagcgat
     7201 gctttgtgaa agcattggct ctacacggac tgggattata tgtatttcaa ggggaagata
     7261 ttccaacacc acctagaatc gatacgaaga aattaaacat gctagagacg attctagaag
     7321 ctttcaatga gcagatgggt aaagatatga ccaaaacctt aatcgaatat gttaatgagc
     7381 agacagataa attagggctc ttagctgata acgttgaaac tattgaacag ttaagctatg
     7441 agcaatgtgc cttgatggag cgagcaatag cagctaagag aaaagaatta gataagaagt
     7501 gatatgagtg tttaaaccat taatcgattc atattcagcg gttctgaaaa agttcaaagg
     7561 aaaagacata ggtgcaacga tcaatgaaga agtgaacatt gatcgactaa agacgatgta
     7621 tgacggctac gatggcgatc gagtcattga aattcgtttt attgatccta gacgtttcac
     7681 tgtacagcaa cgaaacttca tctatgcgct cataggcgat attttcatcg atacaggcat
     7741 gccaacggac ttctggaagg aattcttcta cttccgtttc gaaggtgtca cagggcgcaa
     7801 aataagcctc aaagacgaat cgaatacaac cgtgagtgat gctaacgtct tagcaaatat
     7861 catcctagat tttatctttg aacatcatat tcctttcaaa gaaggctatg agattttacc
     7921 agcgaatcaa gagtattact tctacaaatg cattacaaaa agagtctgct gcatctgtgg
     7981 caaaacagga gctgatattg atcactttga caaagcttta ggaagacgaa agcgcaaaga
     8041 agttgatcat tcagagtaca catttgcagc actctgcaga atccatcaca cagagaaaca
     8101 caaaataggt gtgaccaatt tcaaaaataa gtatcaaatc aaaggaatca agttaagtca
     8161 tgaaacgatt aaaaagttaa ggataggagg ataaatttgg ctgagataag ttggatcaaa
     8221 cttaaaacta ctatgtttga cgatgaaaaa atacgattaa ttcaagctgt tcctgagtcg
     8281 gatgccatca tcgttatatg gattcgatta ctagttttag caggaaagac taacgacgat
     8341 ggtctaatat acatccagag gaacatgcct tataccgaag aaatgcttgc tacattgttt
     8401 ggcaaaaacg taaatacggt tcgcttagca ctaaccacat tggcaaattt caacatgatt
     8461 gatctaggca gtgatggact aattgccatc agtaattggg aaaaacatca aaatatcgag
     8521 gggatggata aagtaaggct aaaaaatgct gaaagaaacc gtaaatacag agaaaggaag
     8581 agacaggaac gtctcaaatt ggaaaatgac gttagcgtga cgtcacgtga cggtacagat
     8641 aaagatatag aagaagataa agatatagat aaagaagaaa agaaaggtaa gtattctaac
     8701 gaacacttac gccttgctaa aaagttgcaa agtaatttaa ctgaagattt tccaaaagaa
     8761 atgactaaag tagatatcga aaaatgggca gacacaatca ggttgatgga agaaagagat
     8821 aaagcatcta tagaagcgat tgagtatgtg atcaattggc tacctacaaa tgaattttgg
     8881 tttggaaata ttagaagtgc taagaaattg agagaaaaat ttgagaagct caaattcgaa
     8941 atcaaagcag ataagaagaa tcataaaaag caaagtcaaa aactacagta cagcaatcct
     9001 agtgaatatg acgacttgcc aatttaaaaa ggagatgcat cacatggaaa gcctagcaaa
     9061 tgctatggag aagctaataa gaagagtatt agtgcaaagc ggaaaatgtc cagaatgtag
     9121 cgaacctttg tatagttggc gagctaaaaa taaggatggt tcagaacgtt gtaaaccaac
     9181 atgcatgagt tgtggttata aagcgttacg tgtgaaagag gatatacaga ccgaacggat
     9241 atataacgac agcttaaaag cacgagcatt gagttttttt caaaatggtt cggtattaac
     9301 agataaaact ttgtttaaat gcaaaatgga gaattatcac gtagtggacc aagaaacgaa
     9361 aattgcttta gaaagagcta aaagctttgt aaatgatgtc ctactgaacc atcctgcaca
     9421 tttcattcta tcagggaaat caggaagcgg aaaaagccac ttgtcaatgg cgacagcttg
     9481 ggaaatactt gagcgctcaa attatgacaa gaaaatactt tttataagct atcaagagtt
     9541 attagagcaa ataaagttct cttataacaa tgctgaactg agaaaagaaa ttgaaggatc
     9601 gcttatagcc gatattaaaa caactgattt ggtggttttt gacgatattg gagctgaatt
     9661 aggtagtggg gtatcaaata gtaggcagtt tacaaacaac acgttaaaca cgctcttaga
     9721 agccagacag aacaaggcaa cgatcatcac aacaaactta tctggtcctg aactaagaga
     9781 agcctacggc gaaagaattg tttctaggat atttaagaat tcagaaggtt atgcgctgaa
     9841 attccaacaa acagcagaca agcgcataaa accagtgaaa ggtagtatcg catgaataaa
     9901 taccgtaata aaaaaactgt tcatcgaggt atcaagttcg attctatcgc agaagcagag
     9961 tactacgatc tagccttatg gcaagctgaa gcgaacggct ggaaagtaaa acttcaggaa
    10021 cgatttgagc tgatgccgaa atttgaacta gacggaaaga agtatcgcaa gatcgagtat
    10081 attcccgact ttacatttta taaaaacggc aagcttgtca aagtcataga tgttaaaggg
    10141 atgcagacaa aagactttaa gatcaaggca aaattgtttt gtcataaata tcaagtgcca
    10201 ttgattttag ctaaaaaata tcggaatacg ttcaaggaag aacggtttta acgaggtggt
    10261 ccatcatgac aacagaagaa gtgattcaaa tgcgtattcg aagccttcaa cgggagattg
    10321 acgatctgga acgaacaaag gcagtgatgg tcaatgaaac ggcgagaaag gcaatcgatt
    10381 tacacatagt gaatttaaga agggaaattc gtagattgga ggaatgagcg tggataagaa
    10441 agcagcaatg aaacgaatca ttgaactgac acattctgag aattggcaag aagacaaaga
    10501 aatagttgca gaagtccaaa aaatcggtaa atcaatgtgg actgaaaagc ctaaacggaa
    10561 aacgccgaga aaaattgcaa tctggcatgg tgatcgaatt ctagtaacag gtactgctga
    10621 acagttatct gaaattactg gtctgagcaa aaacatcatc tgggatagag ctaggagctt
    10681 atggattgat tcaaaaggac gacaatttag gtatgtggag gagaaataat ggatctcatt
    10741 acacaataca gtgatatcat cctcaagaaa atcatgatga agattcagaa agataaaaaa
    10801 tcaaaagaac gagcggaatt agtcaagttg gaaatggctg aaacaggagc aggagtgcga
    10861 agtagcaggc attggaaagc agcagcaaac attgaattct attacaacga aattcaaaaa
    10921 gggttcgatc agatgcgtga gctggatcgg caaacaaatt ggagcaagaa actataccaa
    10981 gatcgtttca agtttgtaga aaagtataga gagatactag acgaatacat ggaggaagcg
    11041 gaatgaacac cagacaccgc agagtagcaa aactaagaaa acaggaactg aatgtactaa
    11101 agacaaagtt tgaaaaagaa tatggaattt cagcagaaga aacatataaa gtggcaagtc
    11161 agtttgttgc tgatgcgagt gagactattc gtaagtttgg gatttcgata ttaaatgatg
    11221 atcgtaaatg ggaggcagaa agatgaaact aaaagacgga ttttacactg atgcttatgg
    11281 aattggtggt ttgatgatgg atctaccaac taagaatcct ataaagcaag aggaatcaga
    11341 aattaaagtc ggtgacatgg ttcgctgcga agcagaaggg ttcatctatc catttcgtgg
    11401 atatgtagag catctctata atcactcagc gatcattcgc attgaaaaca cgatggaatg
    11461 tgacaagcgg ttagcgaaaa gcaaagagaa tttagcagtg gtgagattgg tggatatgga
    11521 agttataaaa tcttaatttt gcttttttac aactatccta caacaatgag cgttattcca
    11581 caactggaag gagaagaggc aattgtgaac attttagaga atatagatat taagcaaaca
    11641 aggaaaaatg ctagacgatt actaaaaaga tacagaaatt tagaacgttt ggtcggacca
    11701 gtgaaaatag acttttccgt gatgactgtt accaaaaatt tgaaattcac aattgacagt
    11761 caaaacgaag aaatcattga agcgataagt actcgagatt cggttatcga agcattaaca
    11821 cggctaagta gaatccattt ccaggtactt tattatagtt attgttttcc taataagatg
    11881 tcaatgtatc aaataggaga aaaattagga tattccgata gaactatcga gagaatgaag
    11941 gcagtagctt tggttgaatt tgctgaggcg tataaatcag gagaactcat ttcacgtaca
    12001 aaataaaaaa agtcggattc ctccgactat gaataatatt tccgacataa gtattatatc
    12061 ataattgggg gaatcagagg atggtacttt tcgatgtaaa gaaatatgag acaccaagcg
    12121 cgaaagatgt tgatatggaa cgcacaaaac ataatgtcgc tgtgtttctt tcagcatatc
    12181 tatcagctag atgtagagta gggcaacctc gagaaccaaa agtgacagca tcttattcct
    12241 tggttccacc ttctacagct gatcatatat ttgaagcaga aagaatgctg atcgataaag
    12301 aagaagcaca ggaagaattt gagtatctgc ataaattgtt tgttcgaggc tattcagcga
    12361 tacagcatcc gcataagcct gatgtgactg aaaggcgcaa gaagatattc tatgatcgtt
    12421 atatcaatgg tctgcccatt tatgtaactg ctcaaaggaa taatactagc gaagaatcgg
    12481 ttaaagtaga atcaaacaga attatcatcc aatttgcttc atcgttagaa ctggttgctt
    12541 tcaagtagcc agtttttaca ctttttatac ccttttatta ccaatttggt ttccatttta
    12601 tacctttttt ataccaatca cttacctatt caacgttgta ttatgatagt gtcgaaagat
    12661 tagtgatagg tcttagacaa aataaaatgt aagggaggaa atctccctca tcgttttaaa
    12721 ttaagcctcg atagacagca gcggaaatat taagaataag gatgtgaact caactccttc
    12781 tgaattcttc gtatgctgct gtctattaaa ttatgtgttg gagggtaaga atatgaaatt
    12841 atcgattgaa ggtacttcag gagaaataaa agaaatcctc tcagctattt gtaatagccg
    12901 agagattagc aatttaatca atatagataa tttaaatgaa tctattgtta ctccaagttc
    12961 ccgagagaaa ttgcagaaat ctgatcagca aaaacaacta aaaatgggat attagtagtt
    13021 ctctcgccta tgatggtaac atctttcaga aagatagatt tgactaccaa actttgctca
    13081 tcatcttttt ctatatcatc aatttttttt gagcgaaatt ctgcaaaaga atccatcata
    13141 gcatcaataa gaggatttac ttttacttca gcatcaaagt ctataggagt tccgcaaatt
    13201 gttgctcctc cagtttgaat aataatatta ttgttagaat ttttagcgaa gagttcaata
    13261 tattcaatca tgtctgaacg gtaatcatca atttttgcca tttttttacc accttaaatt
    13321 atttcagcgg accactcgct gataaataaa attatacact tagtatttat tttcacaata
    13381 ttaatttatc gtaataactt ttgagtaaat agaacaaaaa acctgcacta gtttccgcta
    13441 gtacaggcag tgactatatc ggttgataat ctagcatata ttaaaaataa ttgcaagaaa
    13501 agaaatttat agtggtttat accaaattat caaagcaatg ttattttgtt gctgtctatt
    13561 gttttttaat tattcacacg ataactaaag gtgggtgaag agaaatgatt ccattaataa
    13621 tttcaatttt tgcgctctgt cttaatgtct atatgattgg atttaaaaat gggcaaaata
    13681 aaaaatagta gcagccaaga ataattttat agtgtcactg tggcggaaag ggtagacgct
    13741 aagcatgtgt gctaggtcaa tgcttcggca accatgcaag gttcgattcc ttgccagtga
    13801 ctttagtgga tatccaaggt aaaaggaacg gaagtgggaa tcaggcatga ttcggtagga
    13861 taactgcgag ggcatattaa gttgaccact taagtaaaat aattagggag atgcacctag
    13921 aaatagagtc ggtcgctcta tagggtagtc atcaaattag actttgctat ggttagaccc
    13981 taagccagta aagttgtggc ggtgaaccct tgccgctttg acgtgaagta tctgtggtga
    14041 tacgtctgac ttttaatcag aaggtgcagg ttcgactcct gtcacgtcaa ttagcaaccg
    14101 agggtggtat gaactcgtgt ggtgcgagcc ctagggagga acaggataac cgcctgtgtg
    14161 taggttgcta gtacatatta gatcactcgt tgagtggtct ttttattttg caaaaaggag
    14221 gtaacaacaa tgtatagacc acaatactta gaacagaagc atgaagtaat cactgtgcaa
    14281 aacggtaacg gtgagatagt acgaaagtat agaagaccaa taaagagcaa tacatataaa
    14341 cgaaaggaaa gcaatgaagt tattccattg tatggcaaaa gaatagctaa gtattaaata
    14401 agattgcgaa aggagatggg acatgaccga ggaattctat agatggttat tacagttgat
    14461 aagagaagat tgtttggtta agttctatca gtctcctaaa tggcgcaggc ttagagagaa
    14521 agcgatgaaa cgagatcact atgaatgcca agagtgtaga agactaggta agtatcatag
    14581 agtagagaac gttcatcata taaaggaagt caaggataga cctgacttag ctttagattt
    14641 agataatctt atttgtttat gtgttgaaca tcataatgaa gttcatggca gatatcttac
    14701 agcattagat aaacaagaga agaagataga aagctttgct aacttcgatg caagtgaaag
    14761 gtggtaagtg catgatcatc aatgacaatg gcagagagta tgacacagaa aagattgaag
    14821 agtattcatc ttatactcaa ggattaatta aacgtttgat atacgttcgc tatgtaggta
    14881 ttagggatct gttatcagat aactgttgca gtaaatacaa agtgaatcaa gtaagagaag
    14941 cgttgaataa agataataac gttgaaagaa taaaaaatat ttttggatat agcattgaag
    15001 agattaatta ttacattgac ttcgctgaag ctttcattcc gatggtgaga taaccccccc
    15061 ttaaaataaa tcgcaaattt tttgggggtg atgaaacgga gggggctgtc aggaaaagag
    15121 attttttcga actttatcat gaaaggaggg ctaaaatgtt taaaaacgaa ttgtctcaaa
    15181 atcgctacag agaaaaatta cgccgctctt taataagcca attggaaagt cagaaaacaa
    15241 atattgagcc attcttagat aatgttgatc gttatatcag tttatgggaa acggcgatat
    15301 cactggaaga agatatatcc gagaacggca ttagactgga gaatggtaaa aagaatgaat
    15361 cagtagcgtt gcttgtttct gtcaacaaac aaatgggatt gatgttggat aaacttgcca
    15421 ttactcctga attggtaggt gaagcaaatg aatcaattcc tgagttataa gcatattgaa
    15481 aattggttca aagctataga agaaggcact atcaaggtat gcaaagagca attattgcta
    15541 aaaaattatc tagaagaaag agtctttact agagaagata tttacttcga taagcagatg
    15601 gtagaggatt caatcaatat accagcacaa tactttccat tcgaattaat tccgtgggaa
    15661 aaatttctac aatgttttat ttatggtgtt cgatggaaaa aagataaaac actagtgttc
    15721 aatagatatc tttcattaat gggacgtggt aatggtaaaa ctggttttgc ttcttggaac
    15781 aacttctttc tactaaccgc taaacacggt attaaaaatt atgatattga tatctatgcc
    15841 aataatgaaa gccaagcaaa gactagtttt gatgatgtat ttaaagtaat taaagatcat
    15901 cctgatttag ataaaaaagt atttaaagct acgaaggaag ttattcaaaa tatcgctaca
    15961 aacagcaaac ttcgttataa cacggcaaat gctagaacaa aagatgggaa gcgaccaggt
    16021 gcaaaccgct ttgatgaaat tcacgaaaat gaagattatt caatgataaa tgtggctact
    16081 tctggtggtg gtaaaattcg agattataga gaattttatg atacaactaa tggtcatgtt
    16141 cgtggtggtc cgcttgatga cattatagaa gaatcaaaaa tgattctttc tggagaactt
    16201 ggaattgaca aggatggagc agaattttct agtttgtttc catttatttg tcgcttggat
    16261 aacgataatg aagttgatga tcccgacatg tgggaaaaag cttgtccaac tattaattac
    16321 aatgcagatt taaaacggaa aatgtttcaa gaatactctc aaatgcaacg taatgctggt
    16381 ttaagactta cgttcatgac caaacgaatg aacagaccta tggaagatac acgatttgct
    16441 gttgcttcat atgatgatgt tctgcatacg aaagaaaaag aatttcctga aaaaatggat
    16501 gaagtgatag gaacagtcga ttttgctgat agacgagatt ttgccagcgt tgggttgcta
    16561 ggaaaatacg ataaagatgt ttattttaca caacatactt ttatccacga atcagccctt
    16621 cgattacaaa acatcaaacg agaggttata gatatttcta tagatcaagg aaaatcacag
    16681 atcgttcatg gaaaaaatat agaagctgat tatattgtag gttggtttct tgaaatgagt
    16741 aataaatatt atattaaaaa aatcgctatg gatatgtacc gtgcaaaaat attgaagccc
    16801 gctttagaag aagcaggttt tactgtggaa attgttcgaa gcggatctgt tacacatggt
    16861 atgttaaaag atctggttga tgaccttttt attaatcaac gtttattttt tggtgacgat
    16921 gcgattatgc gttggtattg catgaatgta tatgaagagc atatttctaa tggaaatata
    16981 cgctatgaaa aaatagaacc tgaaactaga aaaacggatg gctttttttc attccttcat
    17041 ggtttgaatt ttttagatga tatttatgat tctgctcctg taacagtcac aaatagctca
    17101 gtagaaaata caggaactgg atttactcct ctagtattct aacttgaaag gaggtgagaa
    17161 agtggggatt tttcaaaagg cggtaggata cttcacaaaa aaagcaacgg ttcctttaga
    17221 agaatacttt tgtaaattgc aagttgattt tgtgtatcga aaatttgcga ttgaaacttg
    17281 tattgatttg attgcaaatg cgatgagtaa agcggaattc aagtcatatg aagatggaaa
    17341 aaataaaaag aatgatcttt actataggct gaatgtagct cctaataaga aaaataatgc
    17401 aacagaattt agaaaaaaac tgatcaggag attaatattc tacaatgaag tattgatcgt
    17461 ttctccgtct aataattcta gcgaaatatt tattgcggat agttgggatg tcacagaata
    17521 tgcattgaaa gatgatgtgt tttctcaagt gcaaattaac aacatagtcc ttgatagaga
    17581 atttctagaa agtgatgtta tctatataaa atacgcagat caacaaatta ggcaactagt
    17641 cgatgcgtat tatcaagcgt atgggaaact catttctagt gccatgaatg tttacaagcg
    17701 ctctaacgct cgtagatacg tactgaaagg gaatttattc cgaccgcaag acaatacaac
    17761 acaagatcaa atcaataaaa tgatgacatc acaatttaag gattttatgg aagctgataa
    17821 tgcaggtgcg gtatttcaat tacaaaatga gtacacatta gaagatttca gcggaaactt
    17881 ccaaagcaat tcaagagata taaaaaactt aatagacgac atctttgaga tgacagcagc
    17941 agcgtttcac gttccgaaaa acctactaaa gggagacatg agtgggttat cggatcaagt
    18001 ggacgctttt ttaatgttcg aaatcatacc gattgctgaa cttattcagg atgcgtttaa
    18061 cgctagtctc tatgaagtag aagaatactt gtcagggaat tttgtacgtg tggatacaac
    18121 tatgatcaag attactagct tcaaagattt ggttgacgct attgatgtag gcattagaaa
    18181 tggagtattt acaatcaacg aaggaagaga acgcgttgga aatgatcgct ctgataaggc
    18241 gatggcagat gaaatattta taactaaaaa caatcaacaa gtatcgaaag gaggtgaggc
    18301 gaatgacgac aatgaaaaca tttctagcag taaagaatga aggcgcagta ccgcaaattt
    18361 ttattcaggg atttattggt tctagttggt tctttgaagg gaatactgac aagggaatca
    18421 aaaatatttt ggatagtcta ggtgatcaag aagaaattga agtagtaatt aattcaaacg
    18481 gtggagacgt atttcaaggg attgctattg ggaacttact taagtcaaat aaagcaaaag
    18541 ttaacgttgt gattaacggc ttagccgcta gtgctgcttc aattatcgca atggctggcg
    18601 atactataaa aatctacaac aatgcacaat tgatgattca ccgcgcttcc acatacggag
    18661 aaggaaatgt cgatgacttc cgtacgattg ctgaccaact ggaatcaatt gataaatcgg
    18721 taaaggcttc atataaaaca cgattcaatg gcacagatga agcattgcaa gaacttcttg
    18781 aaaaagaatc gtttatggat gcagaaacag ctttgagtta tggattggtc gatgaaatta
    18841 tcgatgcaga aaatagctca ggtactgaag ctaaaaaaga acaaagcgtt gaagaaattt
    18901 tgaatgacgt taaagaaaaa agagcagaaa aaattgctgc atttacagca gcattaaata
    18961 aaacatttgg acaaggagat gtaaaataat gacagttaaa aatttaaaag gtgtaacagc
    19021 tgcaagcgac caattgatga aagcttttaa agatggtaac gaagaatctt ttagcgcagc
    19081 tatggtaagc ttatctaagg aaattcagga taaaatttta gaagaagcaa cagcaaaaaa
    19141 tcaagatcaa ttagtattaa tgaaccgtgg tcagcgtgta ttaactacac aagaaacaaa
    19201 attctataac gaagtagtga aaaacgaagg ttttgcaggg gtcgaagaat tagtgccagc
    19261 tactgtattt gaacgtgtat ttgaagattt agaacaatct catccactat tgcaaaaaat
    19321 tacttttgtt aacacaactg gtgtaacaga atggattgtg tcacgtggag tcaatccagc
    19381 atggtggggt aaactttgcg aagctgttaa aaaagtttta gataatggct ttgatgtaat
    19441 taacatgaag cagttcaagc tatcaggtta tattcctgta tgtaaggcaa tgcttgattt
    19501 aggtccagta tggttagatc gttatgtccg tactgtttta gtagaatcat tgagaattgc
    19561 attagaacaa gcaattgttg atggtactgg taaagatatg ccagtcggaa tgatgcgtga
    19621 catgagcaaa caaactagcg gagaatatgc tgaaaaaaaa gcagaaccta ttacagcttt
    19681 agatgctgta actatgggcg gtttgatggc gcgactatca aaattcaata tcgaaggtgt
    19741 gaatgatccg atttatcgta atgtgaatcc ttctgatgtg gtcctaattg tgaatccaac
    19801 tgattactgg tctaaagtat tcccagctaa gactgtacta actgctaatg gagaatacgt
    19861 acaagtattg ccagtaccag tttcagattt gcagtcaacg gctgtgccag aaggaaaagc
    19921 agttattggg gtagcctcag attacttcat gggtgtagga tctacactaa aaattgaagc
    19981 ttcagatgaa taccattttg ttgaagacga acgcatttat ctagctaaac aatatgcaaa
    20041 cggtcaacct aaacgtaacg atagtttcat tgtattagat attagcgctt tgggaactac
    20101 tactacaact acaaaaccaa caaccacaac aactacaaca caagcgtagg tgatcagaat
    20161 gaagtatatt ctttgtcagc tggcaatcaa tcggtttaaa tgggagcttg aagtttgttt
    20221 aactaatctg aagaaactag gaatcaaaga tatcgtattg cttttcagca gacacgatga
    20281 tcagattcct attttttttg agaaggaata tggtgttgaa gttcatgtgt acgatgatct
    20341 gcgggacgac aaagagtata ttccttcgat taaaccatat ttatggtgga aatatttaga
    20401 agaagatcat tcgcgtgagg acgaccgata tttctatatc gattcggatg tcattttcaa
    20461 taaaagaatt aatttgcgca aattgccttc taaagatgat gtttggtatt gtagcgactg
    20521 ctgtagttat ctaagtcttg attatattag aagctgtgaa aacggagaaa atattctaaa
    20581 agatatggca aacattgtaa atgttacagt agaatctttg gaaactataa acactaattc
    20641 aggaggcgca cagtgggtta ttaaccgtcc taaagcgaat tattggaaaa aggtttatct
    20701 ggattctaat cggctatatc gctaccttag agggcaaaaa acaaatatac aaatctggac
    20761 agccgagatg tgggcacagc tttggaacat gatgtatttc aatattggtc ctaaagttca
    20821 cgaggaatta gacttttgtt ttgctactga tccaatagaa aaagttaaag aagtaaaaat
    20881 cttacacaat gctggagtaa caacaaacga tgaagattta tttttcaaag ggagatacgt
    20941 gacttctacg ccttttgatg aagatttatc atttgtaaac aagaaaaaat gctcttacgc
    21001 atatgttaaa gcaattaagg cggtggttag atgacgcctg aacaagtgac tgaagaattg
    21061 ctaatagctg tgaaggataa tatttacgtt acctggaacg aagaagatga gtcaattaaa
    21121 aagatgatag ctaaaaatgc tgtttatctt caaagtaaag tgagtacaac actttctttt
    21181 tctcctgaaa gcttagaata cggattgcta atcgaaagat gtagatacga ctggaatcgt
    21241 gctttagatg agtttgaaca aaatttcgct agtgagttat taggtttcat tcaacattat
    21301 gcgctacaag aatatattgc aggtgatgtg aatggcgaat aatcgtagac tcgaagaaac
    21361 attcaacgat ggttggttaa agattttgac gcaaactacc aaaagaaatg aactaggaaa
    21421 aaagattggt gtagaagata cagaaatcac ttctttaaaa tttagaaatc tttccatgag
    21481 agatagtgat ataacagcta tggatgcgat gggatcgaaa ttaactaaga aagtaaagac
    21541 tccatttcat ccaatcgcca agaaatttaa taaagatcaa tattttatcg taatcgatag
    21601 tatgcgttac aacgttatct atgccgatta cgataatttt tatatctatt tttatcttga
    21661 aagtgtgggt gaatatggtg attgataatt ctaaagaaaa agaacgttta aataagcaaa
    21721 tttctgctat caaaacttcc ttagaagagc attttggcct caaactcttt caagactccg
    21781 taggcgagga tgagctacct gatgatttta attacttcat tctcgaaaca ggagaaatag
    21841 aaatgatcac tgagccaaaa tatagcgtgg gtcaaaatct atatctaact ttctattcag
    21901 aaaatagaga agatttaaca ggagactcac tagatattat ttcattgatt caaaatcgtt
    21961 cgattcgttt tcagagaatg gatcccaatc atttaaaact agagaaccaa gatcgctata
    22021 tcgatcaatt ggtatttacg tttagacgat tattgaagag tgattgtcat ggctaaaaat
    22081 agttgggagc taaaaataaa tggacatgat gaacttcttg tgcggatgga acgctattca
    22141 agcgagagcg aacgactgat taacgaagca ttgaaatcaa aaggttcggc tattgcagtg
    22201 gataggatta cagaaaaaat tcctgtttct gaagcagatt taagaagagg gcaccaacac
    22261 gcaaaaaata gtcgtccact taagactcaa tacattaatt tgggtttcat cattagacct
    22321 acaagaaaat ttgagtattt aaaatatcct gatttgggga taggtacttc taaaagaaat
    22381 cagccggacg aatttatgag aagaggatta ggtcttgcac ttgatccaat tacagaactt
    22441 ctgattcgtc aattcgataa attaaataaa tagggggaac aacaatggct aaaacaaaaa
    22501 ctgtagtaac aacgttcgat aacataagta tcaaacgaat tgcttttaat tttaagaacg
    22561 caggaaatgc aatcgcaacg aattgtaacg gacaattaga tggcgaaaca gaaatgcaaa
    22621 cggtggttaa aaaatgtgga gcgacagaag taaaatcaaa atctaaacca atcaatatga
    22681 cggtaacaat tactgcacat gtaccgatgg aagtttatcg acgtttcaat gggttgaaac
    22741 aagatggacg tattaaacca ggcatttact cttacggtcc tgattccgta ggcgaagatt
    22801 tctcacttgc tgcagagatc gtggatgact tcgaagaaaa tagaaagtta gttggtatgt
    22861 tagcatgcac ttcgaataca ggattaacat tctctattga aaatggtgcg gatgaagtag
    22921 ctgcgttaga actagaagca aaagttatgc aagatgaatt tggtaaattt tatcatgaag
    22981 caattgttgc agaacttgaa gaagacttaa cagatcaatg gatgacgaat ctatctgctg
    23041 atgtgattaa aaaaacttca gttgtgacaa ctacggccac tcaatcacag taaaaaaaac
    23101 ggaggtagcg aaatgaacga agattactca aaaattgaac taaacgatgg aacaattttg
    23161 aatttagaac ctaaactgaa tatcaagaaa ttattgatga tcaatagaga ttttaacaca
    23221 gacgagtttg caaaaatgac tgtgggaaaa ggatccatgg atatttctgt tattcaaggt
    23281 gcgaaggctg tgtatattgc ttaccgccaa gcgaacatga ctgattatat ttcattcgat
    23341 gaatttatcg ataaatggga ttttgatatg gctactgcca gctatattta tcaattgatg
    23401 atgttcaaac aagcacgcga tgcttatcaa aaagaatttg aaaaagcaaa taaggaaaaa
    23461 aagcttcaaa agtaaaaatg ccaaagctct tagttgaaac gtgggtcgat gtctattcga
    23521 tgttgaccga cgttttttct atgccttcag atttggtttt aagcgatatc tgtttagatg
    23581 acattttgca aatggcttac aacaagagtg cttatgaagg atggaaaaac tatgcaataa
    23641 accaatccca gaaaaactaa agaaaggagg taaaaaatgg ctaaaaagag aacagaagca
    23701 gaagtaactt tcatagctaa cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct
    23761 gaattaacta aaaatagagc agaattaaaa ctagaacaag ctcaattaca acagactggt
    23821 tctgaatcag acaagttagg aagtaaatta tcttctttag aaaagcagta tgaattacaa
    23881 agtcaaaaag ttgaagtaac tagtcaacgt ttagccaatg ccaaaaaata ttatggagaa
    23941 aattccaccg aagttcagaa acttgaaaga gaactgatta atcaacaaac agctcagcaa
    24001 aggttatcta atgatataga taaaacgagt aaggcattgg ctcaagcaaa aggcgaaata
    24061 cagacgtacg agtctacaat gcaacagttg gatagtgaac aaaaaaatgt tcaagctagt
    24121 gcttctctga ttgaatccga atacaaaaaa tggcaagtaa ctgctggtca atcagcttct
    24181 gaatccgaga aattagcgaa agcccaagaa tatgtttctc aacaatctga aaatgcagag
    24241 aaaacgatag atatcctgag acgacagtta gaagctacac agtctgagtt tggcgctaca
    24301 tccacagaag caatgcagat ggaggcgaag cttaatgatg ctgaacgtga atttgaagag
    24361 ttaggacaag ctgctaaaaa tgtagataca actaacttgg acgatatcgg aagcaaaata
    24421 gatatgaata atttaatgga agcttctgac gttttaagcg acattggcga taagcttaca
    24481 gaattaggga aacaagcagt ggactctgct aacagtgtag gtagttccca gagtaaaata
    24541 caagctaatt ttggtttgac taaacaagag gctgaagaat taacgaatgt agccagagac
    24601 atttattata aaggttttgg agaatcgtta gatcagtcca cagatgcatt gattttggta
    24661 aagcgtaatt taggcgattt aaataatcaa gatttacaaa atattacgga acaagctatg
    24721 gtcctagaaa acaccatggg cgctgatatg gatgaaacgt tacgtggtgt aaatggctta
    24781 atggtcaact tcggattgag cgctcaagat gcaatggatt taatggtttc gggtactcaa
    24841 aacggtttag ataaaacgca cgaattaggc gacaatatgg cagaatatag ccaattatgg
    24901 agtcaaatgg gatattcagc tgatgaaacg ttcggaatgc ttcaaaatgg tttagatgcg
    24961 ggtgcttata accttgataa agtcaatgac ttagttaagg aaatgggaat atcgttaaca
    25021 gatggtcgat ttgagcaaaa catggatatg tttagtgaaa gtactagaaa agcttttgaa
    25081 gagtggaaaa atggcggagg aacacaaaaa gacgttatta attccatgat tcaagatttt
    25141 agcaatatgg atggtcaata cgaccaatta aataaagctt ctacaatttg gtctgcactt
    25201 ggcgaagata acgcgatgaa agttgtccaa tctttgactg atgttaacca tacatttgat
    25261 gatgttagtg gatctgcaca aaaaatgaat gaagactcta ctactccgtt acaagaatta
    25321 aacggaaaaa tagctgaatt aaaggattca ttagctccta taggcaacac aatcatagat
    25381 gcactcgaac cagtaattga ttttctagga aagatggctg atgcgtttaa taatcttcca
    25441 caaccagtac aggattatgc cgtagcgatt ggcggattga ctgctgcatt tactttatta
    25501 atgccaataa tagttggctt catggctcta ggtggtccta ctacattaat aataggagca
    25561 gttattactg ctattgctgg agttatagca attataaaaa actggggtgc aattactgac
    25621 tggtttagtg gtttatggaa aaaatttact gattggttgg gtgatacttg ggaaagtata
    25681 aaagacggag cctcatcagt ttgggatggg gttaaagaaa cctggtctgg atttgtagat
    25741 tgggttcaag atatttggca aggcgtttct gattggtttg gagagttatg gagcggatta
    25801 gttgaaggag cttccaacat ctggcaagga gtccaagaga cttggcaaac attcattgat
    25861 tgggtttcaa atatttggaa cggagtcaaa gaagtatggt cgattatttg ggcagacatt
    25921 gtaggaattg ttcaaatacc atggacatta ataacgtcat tgattcaagc tggtattaat
    25981 attatcgtgg gtatttttga tgtagctgga cagttattag gcgcagcttg gcaagctgtt
    26041 tggacaccta tttctgattt ccttaaaaat acttgggata ctatgacaca atggataagc
    26101 atcgcttgga atggaattgt aactacattc catactatat ttgatccagt agtggcatgg
    26161 tggaatggta tatggacatc tattagtact acggcttcaa atatttggaa ctcaattagt
    26221 gcaacagctt ctagtatttg gaatagtatc aagaatacaa tcactagctt ggtacaagca
    26281 gctgctacag taattcaaaa tatttggtca actgtatcta gttggttagg tggaatttgg
    26341 aattcaatca gctctacagc atcaaatatc tggagtagcg tgactagcag tataagcaat
    26401 gctataaacg cagctaaaag tgccattcaa agtgtttgga atagtatatc ttcgtggatc
    26461 agcggaattt ggaacggtat caaaaacact gctttgaatc tttggaatgg aattacaagc
    26521 actattagct ctaaagtaaa cgatggaaaa aatgcaattt caagcggttg gtccaatcta
    26581 acaggtattg tttccgacat attcaataat gttaaaagca cgatagctaa tatatgggaa
    26641 ggtatcaaaa agactgttag cgctccgatt gattggatta gagataaaat cagtagtgtc
    26701 tttgataatt tgaatatttc gataccacat attccgttac cacattttaa attgagcgga
    26761 gaattcaatc cattgaaggg gaaaatccca acattgggtg ttgattggta tgcgaaaggt
    26821 agtgtgttta attctccaaa tattatcggt gtcggtgaag caggacctga agcagtttta
    26881 cctttgaaaa gatctgtgct gcaagaaatt ggggatcgta tcttgagtag cacctcagtt
    26941 tcatctaggg cacaaacgat tcaacctgtg aacaattacg aattcaattt cacaattgat
    27001 ggtaacgcag atgaggttac tatgaagcaa acaactcaac aaatcattga tagcattaca
    27061 aaagttcaaa atgataatgc ttcggcatgg cgttaaacag gagagtattt ctcctgtttt
    27121 tttagtttta aaaaggatgt gaaaaaatga ctgattgtat acattctata atcgatggat
    27181 ttcctgatta tttgcataaa ttggctttag cggaaagacc aaccatacct tctccaaaaa
    27241 gacagagagt tgaaacttct gttttaggac ggctaggtgg cttagtacaa gattactcgt
    27301 ttgaagacat gtcgtttaca ttgcactata actatttaga agatgtggaa gaccatcaag
    27361 cattcaagca atcgttttat atcatgcgtc attggttaaa ctatgcaaag aaattagaat
    27421 tctctgatga tcccaacgtc tattatgtta tccagactat cgatattggg gatgcagaaa
    27481 acgatattgt tgaatgggga gagttcgatg taaatatcac tgcgaaacca ttcgcaagag
    27541 ttcaagaaga tgtacctata accgtagata aaccacagtc atttaacttg ctgaataata
    27601 gtttagaaga aagttttcca aagattatca tcactccttc agctacttca tgccaattca
    27661 ccttaaatga ttatgtgttt agttttgaag gcttagtagt gggaactgac atagtcattg
    27721 atagtgattt gatgctttgc tacgaagagc aatcggacgg agatatttta gatcggtcca
    27781 acaaaatgaa gaccatgcaa tatccaacgt tgcaagtgga tattaatcat tttaattgta
    27841 ctggtttgag caaaatacaa atttatcgta atgggttaag gtaggtgaaa tagatgatcg
    27901 ataatttact aactatttac gataaaaatg acgcgaataa tttagctgaa catttatatg
    27961 atacgcaagg tttaggcgct ttgtcagact ggttaacagc tactgttagc aataaactaa
    28021 acggagccga gatatttcag ggtacttatt caataaacgg aactaatgca gatttgattg
    28081 tagaaggacg tattattcag tgttatgtag atgaaaatcg agcaaaacag cgtctacgga
    28141 tttattatgc aaaaacttct gtaataggca atacgataga agtaaaagct gaacctattt
    28201 tcaatgatat aagaaaatcg gtgttgaata aatatgacag cggaacagaa aaaatcactg
    28261 ctactcaggc atggcaaaac gcaaaagttt tagcgaaacc agctatccct tcgcagtttt
    28321 ctttctcgtc attagtagat acgcttgcta atgtgaagat agaaaaggcg aattttttag
    28381 aattctttgg tggaaaagag ggatctattc tagatcgatt tcatggtgag tttctaaaag
    28441 ataataacac attacgtcat gaaaaaagtc taggtacgga tcataaaatc aaagcgattt
    28501 atactaaaaa cttaactggt cttgacttag agatagatgc tcaaagcgtt ttagttggag
    28561 tttatccatt cattagcagt tcttcagaag gagaagacga gatcactcta ccagaagaag
    28621 ttattttcac ggattacgtg gatgattatc ctgctggata tgtttctttt gttgatttta
    28681 aagacaaagc gactgatgta gccacattaa gggaagttgc taaagactgg ttgaaaacaa
    28741 acatagataa acaaaaacca caagtgagtg gttcgattga attagtacca ttgaggcatc
    28801 aaagaggcta tgaaaaattt gttgatctag aaaaagtttc gatgggtgac ggagtagatg
    28861 tgtatcatcc acagttaaaa gtgaatatgt cagcgagaat cgtggaatat acgtttaatg
    28921 ttttaactaa ttcatacgat aaattagttg taggaaacgt caaaacaaac ttcttagaaa
    28981 atacagagaa taatgtcagc aatttgatta atgatgccat tgatcaattg aaaaatgttg
    29041 gcgaaatcag tgatttaatc aatgatattg tagatcatca aactgatatg attactggtc
    29101 aaaatggtgg ttatgtttta ttagatccta aagaagcgcc tagtcgtatt ttgattatgg
    29161 acacaccaga taagaatacc gcaaggaatg ttttacaaat caacaatgct ggtattggtt
    29221 tttctaaaac tggcattaat ggaacatatg aaacggcatg gacgttagat ggcggattca
    29281 atgcctcgtt tattacggct ggtgaaatag taggaattac tattagaggt actacattaa
    29341 ttagtgatgg tgctgattat agaacaagta ttgctaatgg caaaatgact tggtactcaa
    29401 aaaaagttaa caaagatatt atggagctag aagcacgtga ttatgtaagt gctgatgccg
    29461 gtattgtatc atacaccatg aaaactggtg gtggtttcat gattagaaat ccacagggta
    29521 acttggtttt tagtacgtgg gataatggta ataacagacc gtttctatct tttggtgcgc
    29581 ccaatttcag gtatagcaat gctagttatg taacttctgg cgacggtagt tctttaagca
    29641 ttaatggtag tgcgggtaac tcatgggaat ttaaggtagc tggtaggact atgaaattta
    29701 ctagtgatgg tatgctaacg ttaccaggtt gtttttttgg ttcatgggaa gatgggaaac
    29761 ttgctaggtt tgaacaatca acggtacaag tatataaaga ttttactgtt agaggtacta
    29821 aaaactcaac tgtaccaaca gaacattatg gacaacgact attgaacgct tatgaaactc
    29881 cagaatatta tttcgctgat tatggggaag ccgttacagg tgacgatggt aaagttcgtg
    29941 ttgatattga ccccatgttt gctgagacag taaatctaag tcggtatatg acacatgtga
    30001 cacctacaga actagttttg tgtgctgtta ctcatgaaga tattgaccat ttcatcattg
    30061 aaactagtaa gccaaacgta ttagttagat ggaatttagt ggcacaccgt ctagggtatg
    30121 aagatattag attaaaagag gatacagcat atgatagcac agtgcttgac caaaaacgtt
    30181 tttaaaacga agacaaggag gtatataaat ggctagcagt ttatataatt tggctttaga
    30241 tttcagcaaa gaattaaact acaccaaagc tattatggct cgtcagggtg ataaagggat
    30301 tacggtgacg gttaaaccat atttaaatgg cttgcagatg gatacgagtg gcggaacatt
    30361 tactttaaaa ggaacaacac catctaaccg ttacgtagat aatgttgcaa ctagcgtaac
    30421 tagtgaagaa gtcacgtttt ctcttgatgg cacatttatg agtgaagcag gatattataa
    30481 acactgctac gtagaatata gaaaagacaa tcaaattcta acaacgcaag atatcatttt
    30541 tttctcacta ggagtgtctg acatttcgca aggtcaagcc gatgaatatg tttcgcaatt
    30601 agaagagttg attcgaaagt ataatgaaac ttttgatgct tttatggctg aaactaaagg
    30661 tagagtggat agcttaaatc aacagattac tgatttaact ggtcaagcta aaacgctaca
    30721 agacaagtta gatgctctga aagaagaaat ttctaagtta ggtaacttac aagtgatgta
    30781 cagtaacagc attgatttcg ggggctatga ttattcgggg aatccgaatt tgatggctaa
    30841 tataaacgct gatagcttct cgcaaggtag tggtgcctta tctgttgtag atgatggtga
    30901 cgaggtagtg attacgcttg atccaaacca taaattagag gtattaaaac cgaaaagtca
    30961 accagcccta ttaacaggca aaacatatac cgtgagtgta gaaattatgt tagaaggtga
    31021 tttcactgga gaccctagca agataggcct aagatatatt aaaatgccta actgggtatc
    31081 agagctatat acgcgtaata cattaactgc tactaagggt gtatggcaaa aactaactgg
    31141 caccgttaaa attactgctg cgagtgataa cgctgaaagc tggcttataa tgctacaaaa
    31201 taaagacgct aataacagcc tatccggcaa actacgtttg agacacgcta aacttgaaga
    31261 aggctctaca gctacaccat atcagcctaa cttattggca gaaccttata atatgtgtcg
    31321 cgaatatcct aacgaaaata ttgccgatcc taaagttaag ttcccaatca aatctggcga
    31381 ccaccaaata tatcaaggtt acatggaaga agatcttatg ataggtcaaa cgtatactat
    31441 cacacttaaa ggaacaaaac ccgcaagtca aacctttgta gcgtataatc attggactgt
    31501 tcgtttagga gaactaaagc cagttgatgg gttgacagac gtatggtctc taacattcac
    31561 accaacgaat gttgcggcga tgcctaaact ttttcgtgtt tatcaatatc cacaatcaac
    31621 agtaggcgca tgccaaattg actggctcaa gattgaaaaa ggcaacacac gaaccccgaa
    31681 tattagtgag tataaatatc gtggtactgg tatgcgtgat tcaaataacc caaaagacta
    31741 tgtttgggat ctagcaccag aatatgtcga agataatttg gccacagata ttaaaatttc
    31801 tgaaattact ggtaaagcaa acaattatac cgatgggaaa gtatcggaga ttaattcgca
    31861 gttgactgct tcaattaatg aagtagacac cacagctaag gatgctcaaa caaaagcgaa
    31921 tgctaatgcg actgctatag atgaacgcat taatgataca gctactaccg cattttatgg
    31981 cgcacaaggt gaagtctcta acaaaacgaa agtagcggag tatggagtag gaacagggta
    32041 tactactaca gctgtaggag aaacacattt cgaacgtcaa tctaacggat acgttaaatg
    32101 cttaaaagct ggtaagtatt caattagtgc gcaaatacgt gtgcaattgg gcgggaaata
    32161 tgcttcatgg ttatatactg atttatataa agatggaact tctgttgata atttagtatc
    32221 ttatggggtc gacgccttgc aaaatagatt tgcagctagc ggaaacattg taactgattt
    32281 agaagtaaac gatgtactaa atatgcgtac tgaaatcggc gttgcagatg gaattttaca
    32341 atttacatct tgccgtactt tagtcttgac tagactatct gattaataca atatttataa
    32401 ttttgctatc aacacgctca aaggagggtg ttttttattt tgcaatgaaa ggaggctagt
    32461 tggttgaaag acgaagcaat acaagacgtg gtagaacgct tagtgcgtat tgaaacgaaa
    32521 ctggataatt acgaattatt acgcgaaaaa gcggaaagtg caaaagatag agcggatcag
    32581 gcatattcta ttgcgcttaa taatgcggaa gatatcaaag aaatgaaagc caataataaa
    32641 tggtcgtggg gttacatgat cggtttaggc gttacgatca ttggctattt cttgactaaa
    32701 ttgtaaagga ggtgagaaga aatgatttta cccgataagt attatcaagt cattaaatgg
    32761 gcagttttaa cagtattacc agctgcttct gtgttagtag ccacgttagg gaaagcgtat
    32821 ggatggaatg gaacagatat gacagtactc actatcaatg cagtagcaac atttttaggt
    32881 gttatcactg gtgtgtcggc ttataatttg aaaaaatagg aggaaacaaa tgaaaaagaa
    32941 aattactatt actgcgatga gcctattaac ggctcttttt ttattgccaa ttaatgggtt
    33001 tgcctatact atcaacaatg aatttaattt gggcgcaaat gaaggtagct cacaagtagc
    33061 aaataatcag tacattttac tgcatgaaac ggctaatgaa acagcaacag gacgcaatga
    33121 agcgcagtat atgcaacgtt catggactag tgcttacact gcttacattg tgggtgatgg
    33181 cggaattgtt taccaagttg gacaacctgg ttatgtacag tacggtgctg gttcgtatgc
    33241 taatgccaac agtcctgtgc agattgagtt acaacacaca cataataaag caacttttga
    33301 aaagaactat aaagcatacg ttgaattggc gagagattcc gctaagaaat acggtattcc
    33361 gcttacattg gacacgcctt ataaccaacc aggaatcaaa tcacatttat gggtaacaca
    33421 aaacatctgg ggcgatcata cagatcctta tggttatctt tctgaaatgg gcgtaagtaa
    33481 agaaaaatta gcatatgatt tagctcatgg atttaccgat gaaaatccaa caacttctga
    33541 aaacaagcct gtcattgatc caacacgagc tggtgcagct aatcctacac tgacagatgg
    33601 aacaaactac gctcatattg atcagtttgg ggaaattgaa aatgcaaact tgcatgtagc
    33661 tggatggcat attgctaact ataaatacga gtatattttc attatggatt acaatactgg
    33721 gaaagaatta gctagagtaa aagctgatgg aatttataga ccggatgtaa atcaagcgta
    33781 tgggacatct ggaaatgttg gctatcatgt atcttttaac atgcgtaact tccctaataa
    33841 gaaagtctat gtcatgatgc gtgcaacgaa tgatccagaa ggaaacacta aaggcggtgc
    33901 gcaagatttc catgacaaac gttggtattt aaatattcca caacgataaa aaatcccccc
    33961 ct
//
LOCUS       DAIGTA010000026        33863 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.026, whole genome shotgun sequence.
ACCESSION   DAIGTA010000026 DAIGTA010000000
VERSION     DAIGTA010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.026"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            156..2054
                     /locus_tag="NOB43_001357"
     CDS             156..2054
                     /locus_tag="NOB43_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HCI0982223.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(2353..3072)
                     /locus_tag="NOB43_001358"
     CDS             complement(2353..3072)
                     /locus_tag="NOB43_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HCI0982224.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            3409..3741
                     /locus_tag="NOB43_001359"
     CDS             3409..3741
                     /locus_tag="NOB43_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982225.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            3728..5731
                     /locus_tag="NOB43_001360"
     CDS             3728..5731
                     /locus_tag="NOB43_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HCI0982226.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            5750..6220
                     /locus_tag="NOB43_001361"
     CDS             5750..6220
                     /locus_tag="NOB43_001361"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HCI0982227.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            6241..6825
                     /locus_tag="NOB43_001362"
     CDS             6241..6825
                     /locus_tag="NOB43_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HCI0982228.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            6840..7826
                     /locus_tag="NOB43_001363"
     CDS             6840..7826
                     /locus_tag="NOB43_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HCI0982229.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            7816..8127
                     /locus_tag="NOB43_001364"
     CDS             7816..8127
                     /locus_tag="NOB43_001364"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HCI0982230.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            8149..9930
                     /locus_tag="NOB43_001365"
     CDS             8149..9930
                     /locus_tag="NOB43_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HCI0982231.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            9923..11299
                     /locus_tag="NOB43_001366"
     CDS             9923..11299
                     /locus_tag="NOB43_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HCI0982232.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            11306..11941
                     /locus_tag="NOB43_001367"
     CDS             11306..11941
                     /locus_tag="NOB43_001367"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HCI0982233.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            11971..13326
                     /locus_tag="NOB43_001368"
     CDS             11971..13326
                     /locus_tag="NOB43_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HCI0982234.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(13518..14912)
                     /locus_tag="NOB43_001369"
     CDS             complement(13518..14912)
                     /locus_tag="NOB43_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI0982235.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIHPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            15004..15975
                     /locus_tag="NOB43_001370"
     CDS             15004..15975
                     /locus_tag="NOB43_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCI0982236.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            15972..16754
                     /locus_tag="NOB43_001371"
     CDS             15972..16754
                     /locus_tag="NOB43_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCI0982237.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(16923..17294)
                     /locus_tag="NOB43_001372"
     CDS             complement(16923..17294)
                     /locus_tag="NOB43_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0982238.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            17428..17871
                     /locus_tag="NOB43_001373"
     CDS             17428..17871
                     /locus_tag="NOB43_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCI0982239.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(17914..18723)
                     /gene="yidA"
                     /locus_tag="NOB43_001374"
     CDS             complement(17914..18723)
                     /gene="yidA"
                     /locus_tag="NOB43_001374"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCI0982240.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(18742..20109)
                     /locus_tag="NOB43_001375"
     CDS             complement(18742..20109)
                     /locus_tag="NOB43_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0982241.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(20093..20923)
                     /locus_tag="NOB43_001376"
     CDS             complement(20093..20923)
                     /locus_tag="NOB43_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HCI0982242.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            21086..21523
                     /locus_tag="NOB43_001377"
     CDS             21086..21523
                     /locus_tag="NOB43_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HCI0982243.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            21599..22219
                     /locus_tag="NOB43_001378"
     CDS             21599..22219
                     /locus_tag="NOB43_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HCI0982244.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            22408..22914
                     /locus_tag="NOB43_001379"
     CDS             22408..22914
                     /locus_tag="NOB43_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HCI0982245.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            22931..23830
                     /locus_tag="NOB43_001380"
     CDS             22931..23830
                     /locus_tag="NOB43_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCI0982246.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            23917..24801
                     /locus_tag="NOB43_001381"
     CDS             23917..24801
                     /locus_tag="NOB43_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI0982247.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(24993..25064)
                     /locus_tag="NOB43_001382"
     tRNA            complement(24993..25064)
                     /locus_tag="NOB43_001382"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25029..25031),aa:Arg,seq:ccg)
     gene            25124..26458
                     /gene="rpoN"
                     /locus_tag="NOB43_001383"
     CDS             25124..26458
                     /gene="rpoN"
                     /locus_tag="NOB43_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCI0982248.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            26607..27698
                     /locus_tag="NOB43_001384"
     CDS             26607..27698
                     /locus_tag="NOB43_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HCI0982249.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            27739..28740
                     /gene="gap"
                     /locus_tag="NOB43_001385"
     CDS             27739..28740
                     /gene="gap"
                     /locus_tag="NOB43_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI0982250.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            28850..30040
                     /locus_tag="NOB43_001386"
     CDS             28850..30040
                     /locus_tag="NOB43_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCI0982251.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            30144..30899
                     /locus_tag="NOB43_001387"
     CDS             30144..30899
                     /locus_tag="NOB43_001387"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCI0982252.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            31015..32313
                     /gene="eno"
                     /locus_tag="NOB43_001388"
     CDS             31015..32313
                     /gene="eno"
                     /locus_tag="NOB43_001388"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCI0982253.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            32712..33851
                     /locus_tag="NOB43_001389"
     CDS             32712..33851
                     /locus_tag="NOB43_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HCI0982254.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        11186 a         5996 c         7208 g         9473 t
ORIGIN      
        1 aaaaatatag aaggaagctg gacatttatt gttcccagct tcttttttgt atagacctat
       61 ttctattttt ttattatatt ggatatatat attcattgaa aatagagcat aacaacttta
      121 taatgttgag tataccaatt tttggaggcg ttttaatgga ccgctattta gatttacttt
      181 cagagaagtt ccctacaacg gaagatgtca tcacggaaat catcaatctc gaagcaattt
      241 tgcagcttcc aaaaggaaca gagttatttt tgagcgatat acatggcgaa tttcctgctt
      301 ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga aaagatcaaa gaccttttct
      361 ctgaacaaat gacggaaacg gagatcagcc aattcactat ttttacggct tatccagaat
      421 atgtgttgac gactgattgg tacaaaaaac aagataaatc ccagctgatc catcgtttga
      481 tcgatctttt acggtttacg acagtcaaat acactcgatc aaaagttcga aaaggattgc
      541 cgaaagaata tagctatatc attgaggaac tcttgtatat cgatgatcgt atcaacggga
      601 aaaaagacta tgtaaaaaaa atcattgaac aacttgtctt gatgaaggaa gaagaaaaat
      661 ttttaacaaa acttgcgcag acgatccaaa aatctgtcat cgatcatttg catatcgtgg
      721 gtgatatttt tgatcgagga actcaagcag ccaaagtaat ggatcgaatc atggattttt
      781 cctctgtaga tatccagtgg gggaatcatg atattttgtg gattggtgcg tattgcggct
      841 ctgaggcatg tttattgacg cttttacgga ttgccgcacg ctacaactat ttatttgaat
      901 tagagaaaga atatggatta aatttacgtc cattattttc ttttgcccat caaacctatc
      961 agaagaatcc agtatttacc cctaaaaaca ggaaagatct atctgaaaga gagcaagaag
     1021 aattagaaaa gatccatcaa gcactttcta tcctccaatt caaatcagaa catcagttgt
     1081 tgaatcgacg acctgaattt aaaatggacg atcgtaaatt gttggaaaaa atcaactatg
     1141 aggaatcaac gatcgtttta gaaggtcagc tctatgagtt gaaagggact tgttttcaaa
     1201 cgatccagcc agatgatcct aaaaaattct tggaagagga acaaaaagtg atcgatagtt
     1261 tgatgtattc attccagcac tcgttaagaa tgcaaaaaca catgacgttt ttgatcgaaa
     1321 aagggggaat gtatctcacg aacaatcagc atgtactgtt ccatggctgt atacctgtag
     1381 atgaaaaggg gcagctctta gcatttgaat tagaccaatc ttatcgcgga aaagaactgc
     1441 tgggattttt tgaaaaacag ataactgaaa gcgcaaaaga tttgactgca aatgaagatt
     1501 tggcgaccga tttgatttgg tatgcgtgga gcgggccatt ttcgccttta ttcggcaaga
     1561 gtaaaatggc aacttttgag cgctattttc tcacagagcc tcatacgcac gtcgaaaaaa
     1621 gcaatcccta ttatcacttg cgagatgaag agtggttcag tgaaaaaatt ttggcagaat
     1681 tcgatgcaaa agaagaaggt tcagcaatca tcaatggaca cacgccagta aaagtaaaaa
     1741 aaggagagtc accgatcaaa gcaaacggaa aagcatttgt tattgacgga ggtctatcca
     1801 aagcttatca aaaaacaacc gggattgctg gctactcatt actatgcaat tcttacggtt
     1861 tccaaatcgt gacacattat ccgttcttgc ctattgaaca acaatttgca aaaaaatctg
     1921 atcaaacgaa tgtaaaaaaa gtgatcgagc agcagctccc acgcaaactt aatcggaata
     1981 cgacaaaagg aatggaatta cagcaacaga ttactcaact ccaaaggctg ttggattatc
     2041 gaaaggacga ttgagaaaaa tgctagccaa cattgctcaa tagactaaaa agcgactgca
     2101 acaaaaggcg tgtcgcagtc tccttcggaa ttagctcaaa aaacggtaaa atattagaag
     2161 ctatttttct gtttatttct ctaatactca ggtcagggcg ctgatttcac gacctcttcc
     2221 ttaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatatccaa caaacatgag
     2281 aagctgtttt ttgaaattgc tccttgtgac tcagagttga acggcaggct cacgacctaa
     2341 tcagaaaaac gattaaaatt cattcacaaa gaaatcgaat aaacgctgtt cagatgaatc
     2401 tacacgatga gaaagttccg gatgccattg gacaccaagg attttgtgca tattatcttt
     2461 actttggact gcttcaatga gtccatcgtt ggaaaaggcg atggctttta acaaaggaga
     2521 aagatctttg actgcctgat gatgatagga attcacaaag tatgaatcag ggagaaggtc
     2581 acttaataaa ctgtccgaaa cgattttgac ttcgtgagtt gcaaactgcg gggcagtggg
     2641 ctgttgttcg tgttttacgg accattttgg atataatgaa agatcttgat aaagtgttcc
     2701 ctccaacacg acattcaata gttgaagtcc tcggcagact gcaaaaatcg gttttctttg
     2761 tttcaatgct tccaagatca atgcctgttc gaattggtct cgttgaatat ttgtttccgt
     2821 cagttttgga tgagggtctt ccatgtaaag ttgcggacta acatcctgac cgcctgcaag
     2881 aatgagtttg tcgattttct caattagttg aggcgctgaa tctggagaca tgactggcag
     2941 aataagaggt aatccttgag catctaaaac tgcatccaca aatccctgcg gtgtatagct
     3001 tacttgattt ccttggaaag tatctgtcgc tcgaatcagt tgattcccgg caatgccgat
     3061 gattggtttc atttttattc cccctaaagt agactaattg taacaaggat ttaaaaaaat
     3121 ttaaactatg taagacttgc ccctatactt atctgttctt gctgtgttac tatctgtaaa
     3181 gagaattttc gtgtgaaatt catgacgata gttgaaaata ttgcttaatt tgttataata
     3241 aaaagtaagc agaaataaaa aggttgggcg taagcttcaa ggatctagtt cttcaagggg
     3301 tgagaaggac attttattga aggggcctgc ctatactaag ttatctttag aggtacatac
     3361 tttcaatgaa aaaagaaagc atgtacctct tttttaaatc gaaaggaagt gaagcaagtg
     3421 ttagaagctt tggaacaaat ccgaaaagca gaagaagaaa atgagaagcg tgctcgaacc
     3481 ctacggcagc agttgaagac ctatgcagaa gaaaaagagc aagaattgga gataatccaa
     3541 acgaacagtc ggcaacagct gaaacagttg gtagaagaaa aagaacaatt cgaaaagcaa
     3601 gaattagaaa aagaaaaaat gaaattgaaa gcagaagcag acaaggtgca agcaactttg
     3661 aaagaccaat atcaaaagca tcagagtcaa gcaatcggtg caatcattga aagggtgaaa
     3721 gaaacttatg gccgtcacta agatggaaaa agtgaccctc atttcagata aaagaaatca
     3781 ggagaggatt ttacaagcag tacaaggaat ccaaaatgtt gaaatccggg atctgtatca
     3841 aaatagaaca aacaaccagt gggtagaaaa atattttcca gataccacga ttattgataa
     3901 agaagcaaaa ttaagcgctt taggcaatcg gctgaaagac atccaagaag ctatccaatt
     3961 catacaacac cacggcgata gccgtcaaaa gaaactccat ttgaaacgtc aagaactttc
     4021 cttacaagac ttggaagcaa attattccga agaaaatttc atgaataaat tagaagaagt
     4081 ccttgattta aaagaaaagt gggaacagct aactgaaaaa cgtgatcgtt tagaagaaga
     4141 ggaagaatgg cttcttcatt ggcaacagct ggatattgct ccaagtatgt atgcaagtaa
     4201 gacgaccatt tttgagatgg ggactgtgag tgcagcaaat tttgaaagtt tcaaggaaga
     4261 actaagtaag cttgatgacg tttatatgga agaaatagat tatacgccaa aacaagttta
     4321 tctttcgtat gttgctttaa aaaaatcagt tgctgctata gaagaaattg ctgggaaata
     4381 cgggttcaat aaagaaacgt atccttatga acaaaatcct aaagaaaaat tgcaagaaac
     4441 caaacagcaa ttatccattg ttcacgagca gcaaaaaaag ataacgacag cgttaggtca
     4501 gtgcagcggc tatatccaag aatttgaatg ggtagaagaa gtcacacttg ccgttgcaga
     4561 acgggaaaaa gtaaaagaac ggtttatcca tgccacttat ctgatcgttt tgcaaggttg
     4621 ggtagatgca gaagaaaaac agaatttgat gcatgtgtta aacgaaactg tatcagaaga
     4681 agatatatac gttagtttcg aaacaccaaa ctcagaagag attcagcagg aagtccctac
     4741 taaattgaaa aaccatccgc ttatcgaacc ttttgaattg ctgactgaaa tgtacagtct
     4801 gccaaaatat gaagaagtag atccaacgcc ttggatgaca ccattttatc ttgtcttctt
     4861 cgggatgatg gtcgcagatg ttggttacgg attgctgatg ctcattggga caatactagc
     4921 tcaaaaacta tttgttttac cccgcgggat gaaacgtttc gtaaaattct ttgagattct
     4981 ctcggtacca tcgatcatct ggggattgat ctacagttca tttttcggac aggcattacc
     5041 aaaagaacta tttggtatcc gcttgccttt cccaatccta tctacgacgg atgacgtcaa
     5101 tacgattttg attttatccg tgattttcgg tctgatacag atcttggttg gattattcgt
     5161 ggcagcaaag gaaaatatca ggaggaaaga ttacttgagt gctgtcagtg atggttttgc
     5221 ctggcaaggg atcctgattg ggatcgttat tgcattgatt ggtgtcatgt tgataaaaaa
     5281 tacagcattt gtttatcttg gcgcggggct atcgatcatt gctgctttat gtatcttaat
     5341 cgtgccgatt atccaatcgc cgtctaaagt caagggtgct gccaaaggag cgtataatct
     5401 ttacggattg actggttata tcggtgattt agtcagttat acacgtttga tggcactagg
     5461 tatttcaggc ggaagtattg gcgcggcatt caatatgcta gttgctttca tgccgccagc
     5521 cgctcgattc agtgtaggga tccttttgat catcgcttta cacgcactga atatgttttt
     5581 gacactgtta agtgcctatg tccatggtgc acgattgcag tatgtcgaat tttttggaaa
     5641 attttataca ggaggcggac gtgcctttga cccgctgaaa acggcggaaa aatacgtcaa
     5701 catcaatcat aagaaaaaaa acaataaata attggaggat ttttatacaa tgatggatta
     5761 cttaattagt caaaatggtg gaatggtatt tgcagtatta gcgatggcaa cagcgacgat
     5821 tttttcaggg attggttcag ctaaaggtgt tggaatgaca ggtgaggcag cagcagcgtt
     5881 aacaacaagt caacccgaaa aattcggaca ggctttgatt ctgcaattgc ttccaggtac
     5941 gcaagggttg tatggattcg ttatcgcctt tttgattttt atcaacttag gaaatgatat
     6001 gtcagttgta caaggattga actttctagg cgcttctctg ccgattgctt ttacaggttt
     6061 gttttcaggt atcgcccaag ggaaagttgc agcagcaggt atccaaattt tagcgaaaaa
     6121 acctgaacat gctacaaaag gaatcatttt tgctgcgatg gttgaaacat atgcgatttt
     6181 aggtttcgtt atttccttcc tattagtatt gaatgcctaa gcataaagga ggaaaagcag
     6241 atgaacgcca ttgaaaaaat catctctcag atgaatgaag cagcagagca agaaagagcg
     6301 gcgttagagc aagaagagcg aatgaagatc gatcaaaact ttgaacaaaa acgtacgcaa
     6361 atcgaaacag aacatcaaaa acaaaaagaa aaacaaatcg aattacttga aaaaaaatac
     6421 cgtcagctta ggaatcgcca acaagtagaa gtacgacaag aaaatttgaa tgcgaagcag
     6481 gaatttttac gacgattgtt tgcagatgca atagctgaaa tggagaattg ggatgaatct
     6541 gaacaaatcc agtttatcaa aaattcattg tattcattac ctttgacagg caaagtaaca
     6601 ttcattgctg gagaaaaatc agcagcttat ctttctcaga cattgctgga tgaatggaac
     6661 aatgaacttc cctttatgat ggttttaagt gatgaaactg ttgctgatca agcgggtttt
     6721 ctgataaacg atcaaggagt tcagtataat tttcttttca gcagccttgt acaagatatc
     6781 caaggaacga tgagttttga gattgccaat caattattcg aataaggagg gatcagtgta
     6841 tggaatacca cgaactaaat cccttgattc gcggaagaga gcttgaactt ttgtccaatg
     6901 agacatttga acggatgatt caaacaaatt ctgtcgaagc acttggtgaa atattgaaat
     6961 ccacgattta cagtccatat atttatgacg gatatgaata tgacttcgaa cagaatcttt
     7021 taaaggagca gagccgtcta tttcgctggt taaaggaatc agcaccggag cctgaaatcg
     7081 tttggatcta tacgatgcgc tatactttcc ataatctgaa ggttttgaca aaagccgaga
     7141 tgacaaatca aaatctggac catttgtata tcgacgatgg attttattca ttagaaacct
     7201 tgaaggatgc cattcatacg caagtttcaa atgaactccc tgaaagcatt atggacagta
     7261 tacgagaagt acgtgattat tttgaagagt ctaccattct tcagggaatt gacgtgattt
     7321 atgatcgaca gtttttgaca gagcagcgac ggcttgccga taagctagga tatcaagaat
     7381 tgctgacaga agtcattgct tttattgact tgaccaatat cacaacgatg gctcgaggaa
     7441 tattgcagaa aagaacatat gggttcatga cgacggtact ttccagctcg ggaagtatcg
     7501 aaaaagaagt atttttgaac tttgtagata aagatatgga agattacacg aattttctat
     7561 tagagacaga ttatgctgat tttctgcgcc ctgtcatccg tgagggaaat cttgatctcg
     7621 taaagcttga acagttgaaa gatgattatc taagttcatt gtatcaagaa gcacaaaccc
     7681 aggctttcgg accactgcca ctactagcct ttttgaacgc aaaagaggta gaaagcaaaa
     7741 accttcgttt actggttatc ggcaaaagaa gccatttcga accagaaaca atcagaaagc
     7801 gggtgagaca agtctatgac gcataagatc ggtgtagttg gcgacaaaga ttctgttttg
     7861 ccattcaaat tgtttggctt tgatgttcgt tatggtacaa ccaagcaaac cgttcgtcag
     7921 gcaattgaag aaatggcaaa gaatgagtat ggcgtgattt atgtcacaga gcaatgtgca
     7981 gcattgagcc cagaaacgat cgaacgttac aaggaacaaa tgatacctgc tatcgtattg
     8041 attcccaatc atcaaggatc attagggata gggctggaag aaattcaaaa aaacgtagaa
     8101 aaagcagtag gtcaaaatat cttatagtat gaaaaggaga tagaaatttt gcaaattgga
     8161 aaaatcataa aagtctccgg acctcttgta atggctgaga acatgtctga tgccagtatc
     8221 caagacatgt gtctagtggg agatctagga gttatcggag aaattatcga gatgcgtggc
     8281 gatgtggcgt ctattcaagt atatgaagag acttctggaa ttggtccagg cgaaccggtt
     8341 cgctctactg gtgaagcttt atctgttgaa ttaggaccag ggatcatttc acaaatgttt
     8401 gacggaatcc aacggccatt agataccttt atggaaatca cacaaagtaa tttcttaggg
     8461 cgcggagttc aattgcccgc attggaccat gagaaaaaat ggtggttcga accaacagta
     8521 gaagccggag aaacggtgag tgctggagat gttatcggga tcgtagaaga aacaaaagtt
     8581 ataaaacata aaatcatggt gccaaatggg ataaaaggaa cgatcaaaac aatcgaaaaa
     8641 ggttcattca ctattgatga aacagtatgt gtcattgaaa ccgaaaatgg tgacaaaaat
     8701 ttgacgatgc ttcaaaaatg gccagtaaga cgtagtcggc caatcaaaga aaaattaaac
     8761 ccggatgcac ccatgatcac tggacagcga gtgattgata cattcttccc agtgacaaaa
     8821 ggaggagcag cagctgtacc tggtcctttt ggtgcaggga aaacagtcgt tcagcatcaa
     8881 attgcaaaat gggccgatgt ggacatggtt gtctatgtgg gatgtggcga gcgtggaaat
     8941 gagatgacgg atgttttaaa tgaattccct gaattgattg accctaatac aggagaatcg
     9001 ttgatggaac gtacggtatt gattgctaat acatcaaaca tgccagtagc agctcgagaa
     9061 gcttctatct atacgggaat cacaattgcg gaatatttcc gtgacatggg ttatgacgtt
     9121 gctatcatgg cagactccac ttcacgatgg gcagaagcac ttcgtgagat gagcggacgt
     9181 ttggaagaaa tgcctggtga tgaaggttat ccagcttatc ttggttcacg gcttgcggaa
     9241 tactatgaac gatctggaag agtcattgca ttaggatcag aaggtcgcga aggaagtata
     9301 accgcaatca gtgctgtatc cccgtctgga ggggatattt cggaaccagt cacacaaaat
     9361 acattgcggg tcgtaaaagt attctggggt cttgattcca gtttagccca aaaaagacat
     9421 tttccttcga tcgattggat acaaagctat tctctttatt caacagaagt agggaagtat
     9481 atggatcata tccttcaagc tgactgggca tccatggtca ccgagggcat gcgtattttg
     9541 caggaagaac agcagctgaa tgaaatcgtg cgtttggtag ggattgattc cctttcagat
     9601 aatgaccgtc tgacattaga agtggcaaaa tccattcgtg aagattattt gcagcaaaat
     9661 gcttttgatg atgtcgatac attcacttca agagagaaac aattcaaaat gttgaagatg
     9721 atcttgacct ttggtgaaga aggacgccgt gcgttgtcgt taggtgctta tttaagtgag
     9781 atcatggacg gtaccgtatc gattcgtgaa aggatcggac gaagcaaata tatcccggaa
     9841 acagaattag aaaaactaga tcaaattatt ggtgaaatca agcaaacgat gcaaacgatc
     9901 gtttcagaag gaggcatgag caatgattaa agaatatcgt acgatcggtg aagtcgtcgg
     9961 tccattgatg gcggttgaaa aagttgctgg tgtcaaatat gaagaattaa tcgaagtccg
    10021 tatgcaaaat ggcgagattc gtcgtggaca agtattggaa gtccaagaag ataaagcaat
    10081 ggtccaaata ttcgaaggaa caagtggtat caatttacgt gactcttctg tacgattttt
    10141 aggccatcct ttagaactag gtgtatcgga agacatgatc ggtcgagtat tcgatggttt
    10201 gggacgaccg aaagataacg gaccagagat cctgcctgaa aagcatttgg atattaacgg
    10261 agaagtaatc aatccagtag ctcgggatta tccagatgag tttatccaaa caggtatctc
    10321 tgcaatcgat catttgaata cattagttcg tgggcaaaaa ttaccagtat tttctggctc
    10381 tggtcttcct cataaagaat tagctgctca gatcgcgcga caagcaacgg tactcgattc
    10441 atcagatgat ttcgccgtag tctttgctgc tattggaatc acttttgaag aagctgaatt
    10501 tttcatggaa gattttcgtc aaacgggcgc aatcgaccgt tctgtcatgt ttatgaattt
    10561 agcaaacgac cctgcaatcg aacgtatcgc tactcctcgt atggctttga ctgctgcaga
    10621 atatcttgct tatgaaaagg gaatgcatgt tttggttatc atgacagaca tgaccaacta
    10681 tgcagaggca ttgcgagaga tttctgcagc acggcgagaa gttccaggaa gaagaggata
    10741 tcctgggtat ctttacacga acttagctac tttattcgaa cgagcaggaa gaatccgcgg
    10801 actaaaagga tcggttactc aaattccgat tctaacaatg ccagaagacg ataaaactca
    10861 tccaatccct gacttgactg gttatattac agaaggacag atcatcttga ctagagagct
    10921 ttacaagagt gggattcagc caccaattga tgtactcccg tctctttcgc ggttaaaaga
    10981 taagggaact ggacccggaa agacaagaga agaccatgca gctacgatga atcagctttt
    11041 tgcagcctat gcacaaggaa aacaggcaaa agaattagcc gtagttttag gtgaatctgc
    11101 tttatctgat gtagacaaga tctatgcgaa gtttgctgag cggtttgaaa aagaatatgt
    11161 caatcaagga ttctacacga accgttcgat tactgaaaca cttgatctag ggtgggaact
    11221 gctatcgatg ttgccaagaa ccgaattaaa acgaatcaaa gacgacatgc tggacaaata
    11281 tctgccagaa gggaagtgag ttctgatggc acgattgaat gtgaatccga cccgcatgga
    11341 attgactcga ttgaaaaaac agttgacaac tgccacaaga gggcataaat tattaaaaga
    11401 taagcaagat gaactgatgc gtcaattcat cctgttgatt cgaaagaaca accagctgcg
    11461 tcaagaaatg gaagagtcta tgacagaagc aatgtctgat tttgtattgg caaatgcttc
    11521 gatcacggaa cctttcatcg aagaattatt tgttttgccg gcggaaaacg ttgatttgtc
    11581 tatcgtagac aaaaatatca tgagtgtaaa agtacctgtg atgaattttg aatatgatga
    11641 acagctgaca gacacacctt tggaatacgg gtatttgaat tccagtgccg aactggatcg
    11701 gtcaatcgat cggtttacta ccctgcttcc aaaacttttg gaactgacag aaatcgaaaa
    11761 aacttgtcaa ctgatggcga gtgaaatcga aaagacacgt cggcgagtca atgcattaga
    11821 atatatgacg atccctcaat tagaagaaac gatctattat attcgtatga agctggaaga
    11881 aaacgagcgc gcagaagtaa caaggttgat caaagtaaaa aatatgggta ccactgacta
    11941 agtggtatct ttttttaaaa gaggaaaacg atgattaaac aaagcaaaca aataaagaaa
    12001 cgtttgccgg ctgttcagct tctcgcatta ggattttttc tcctgatttt agttggcggc
    12061 ggcctactta ccctaccatt ttttagtaat agtgggcatg ggacaaattt tatcgatgcg
    12121 cttttcactg caacttctgc tgtctgtgta acgggattga caacattgaa tacagcagag
    12181 cattggaaca gtgctggtca atttttgatc atgcttttga ttgagatcgg cggtcttggt
    12241 tttatgatgg ttccgattct atgctttgca ttgataaaga agaaagtcag tctcagcaca
    12301 cgtattatat taaaagaagc gctgaatcta gaagaagtat caggtgtgat gaagctcatg
    12361 ctttacatcc taaaattggc ctttgttatc caattgattg gtacggttgc tttatctttt
    12421 gtatttgtgc ctgaatttgg ctggttgaaa ggtatctggt acagtttgtt ccatgcaatc
    12481 tctagttttt gtaatgcagg gtttgatttg ttaggagaca gtttagccaa tcaccagcaa
    12541 aatgtttatt tgatcatggt ggtatctgct ttgatcattt ctggtgggtt aggcttcatc
    12601 gtatggcgtg atttactgga atatcatcag aaaaagaaga tgacgattca ttcaaaaatc
    12661 gcattaaccg ttacaggtac ccttttatta ggcggattcg ttgtgttctt tttcacagag
    12721 cgcaatgggg caacgctagt ggaagggaat atgtttcaac gattggcaaa cacctttttt
    12781 atgagtgtga cacctagaac ggctggatat tattcagttg attacctcca tatgagccat
    12841 gcaggtctga ttttaacgat gtttttgatg tacatcggcg gaacatctgg gtcgacggcc
    12901 ggcggattga aaacaactac gttaggtgtg ttgctgatcc agatgcgttc gatgttgaaa
    12961 ggacgtacga gagcggaagc atttggccgt accatccgac aaggcgcagt gttgcgggca
    13021 cttactttat tttttgttac gttgacgttg tgtgtagtcg ccatcatgat tttatcggtg
    13081 actgaaacga tacctaaaac ttctggcatc gaatatattg cttttgaggt cttctctgcg
    13141 tttggtacag taggtcttac gatgggattg acgccagact tgactgcaat agggaaattg
    13201 atcattatag cgcttatgta cattggacga gttggtgtat tgactgtggt cttctctctg
    13261 atgacaaaag cacaaagaac acaatcaaaa tacaaatatc cagaagaaag tgtcatgatt
    13321 ggataatttc atcttctgac agaaacctag tgatttagta aaataagaaa ataaaataat
    13381 ttttcttgct tcttggatac tttaagtgca aaatgttcgt ttattttttg aggcactacc
    13441 cgttgttgaa cctcgggtag tgcctctttt ttattgaaag gaatcaataa gatttgattc
    13501 ctttatttat caataggtta taattcatat ttttttattt tttcttttac gatacttagt
    13561 ccagaagcta aaatttcaag gttattagag gatagggaaa ttcgaacgaa tgcatctggt
    13621 tgcgcacgtg tagtaaagcg tctggaatga taaagtcgga taccgttagc aagaaagtca
    13681 ttctcaatta tcttagggtc aatctcagga tcaactggaa gaattcgata gtaagggaca
    13741 cgattcgttg gtttttctac tttgaaaaga gaatcaaaaa gctgattggc tctttttgta
    13801 agacttaatt tagtttctaa gatcctattt gcttcatttg aatggaggat ttgagtgatg
    13861 acttccacat ctaatccaga agttttcaca tttatattaa aaattgcttg ttctatcttg
    13921 ctttggacat gtactggaac tacaagataa gcaactcgca atccagaaca aataaatttt
    13981 gtcattccag ctaagtagat tgtttggtta ggtaataaat tttggaaagg atgaatgatc
    14041 gtatgttgat agtaagttgt taaaaatgaa tggatatcat cttcaataac ccatagacct
    14101 tctttttcaa tcacttcggc taattgctct cgtcttttgt gagagatttg aaaccctata
    14161 ggattattac aagaaggcat aagaaagaca ccatgaatct tcttttttct acattcctga
    14221 atcaatatat caggtcgcat tccttgctcg tcaaaatcaa ttggaacgat ctctaaatga
    14281 tataactgag ccaattcaat gaaattagcg tatgtatatc ggtctgttgc tattctatca
    14341 cctggagaga aaagtgcaga aagtgtgata gccaatccat tttgaacacc ggaaacaata
    14401 gatagagatt ctaaggacgg aatgactcct tgagttttta accaatttgc tgcagtagtc
    14461 aattgaaaat ttgtgccttt gggatcttgg taattaagca aaccaacaag atttgggtta
    14521 ttactagttg attgaataaa cgggacaacg aatttattac attcttcaaa agaactaacc
    14581 agaccaaaat caatgatatg ttcggttact tcattggtag agatggtgat ggactcaaag
    14641 acattgggag aaataaatgt gccacttcca atattcgtat acagcaaacc tttctcaatt
    14701 ccatatttat aagccttgcc aacggtagta aaatttaaat ctaaataatc agctagctct
    14761 ctttgggagg gtaactgagt gtttttctgt aatttattct ttaaaatatc ttgttctaat
    14821 tgttgaatca acgatcgata ataaggacgc ttcaattttt gtttgtctgg tcgccaagtt
    14881 aacgggtaat tgtcataaga attaataggc attttctcca ctccttaaaa ttgtatacca
    14941 tacaatttta ccattgattg tattgatttt agaagttaat cttttgtgag gagggaattg
    15001 tctatgaaaa ttattaattt tgaggaagta gtagcttctt ttagttttga agaagcgatt
    15061 caagtaatga aaaaatgttt ttttgattat gaaagtggta aaatcagcca aaatcctcga
    15121 ttggtggaaa ttttacctga cggaaaaggc aaaaatatgt ttgcgatgat gcctgcttat
    15181 ttgggggaga acagatattt tggcacaaaa gtcattaccg cttttccgga taatcatcag
    15241 tatcatttac cttctcattt aggagagatt ttcttgtttg atgctcaaaa cggactaccc
    15301 aaagcattga taaacgcaaa tgcagtcacc tggattcgaa cagctgctgt atctgcgctg
    15361 gcaacagatt acttagcaaa tccgcatgca gaaacacttg ctttaattgg agctggtcaa
    15421 caagcattgt cgcatttgac tgcgatttct accattcgtc ccatcactac agtgtttgtt
    15481 tacgatattt tagaagaaag acgaaatact tttatcgcta aagctaaaaa acagtatcct
    15541 aaaataacgt ttataaatgc aatatcagta gaagatgcag tacgtccagc ggaaatcatt
    15601 tgtacgttga cctctagtaa agaggcattt cttcaaaaag agtgggtaag ggaagacgca
    15661 catatcaatg ctgtgggcac atttactcct gatacaagag agataagtac atcgttgatg
    15721 gaaacttctc aaatctatgt agatgattac tcagctgcct taacagaaag cggggacctg
    15781 cttatagcca tggcagaagg agatttagag gaatcttgta ttgttggtac attaggcgaa
    15841 ttagtttctg agaaaaaaac attttataaa ggagaatcga ggccgacgat tttcgacgca
    15901 gttggtctag ctattgaaga tctttgttgt gcagaatata tttataacaa attagagaaa
    15961 ggggctttaa aatgaactta gattattacg tagttgatgc atttgcagat gaggtgttca
    16021 aaggaaatcc agcagcggtt tatgtgctag aagaatggct gccagaaggt acgatgcaaa
    16081 aaattgccat tgaaaacaat ttatctgaaa cagcatttac agtgaagaaa aaccaagaat
    16141 ttgagcttag atggtttacg ccagatcgag aaatcgatct ttgtggtcac gcgacattag
    16201 caacagcatt tgttttattt aactattaca aaatacctga tgaaacgatt aaattttcta
    16261 ctcaaagcgg taatctattt gtgacaagaa ttaaagatta ttattacatg gattttccta
    16321 gtattatgcc gaaaaaagtg ccgatattgt ctgaatatga agaagcgatt ggggctaaga
    16381 ttaaagaagc ctacttagca cgtgatttat ttttcgtatt agaagatgaa aaaacggtgg
    16441 ctaaattgca gccagatttt acagctatca aaaattttga attaggaata ggagtcatcg
    16501 tgacagcaga aagtgtgcaa aaagactttg tttctagaac cttctttcca aaattaacaa
    16561 tcaatgaaga tccagtatgt ggatcagcac attctaatct tattccttat tgggcagaaa
    16621 gaatgaataa aacaaaattg tcagcttatc aaatgtcatc aaggggcggg gatctagaat
    16681 gtgaattaaa agaagatcgt gtgataatag gaggaaaagc agttttgttt tctaaaggta
    16741 cctcgtttat ttgatttctt tcaaatgaat taaaaataaa ttggtggaga gtggcaacct
    16801 tatagctaca atggttgtta aaaaaagacg caaacttttt caatttaatg aaaagtttgc
    16861 gtctcatttt aattattggt gtttgttttt tattcaatca agagtaaaat gccccatact
    16921 aactatcctc ggatgacttc gattttataa ccatcagggt caatgacaaa gtagtaagaa
    16981 ggcgcagtgc caggtaatcc ttttaagtca gtaatctcaa gaccggcagc tttatgttgc
    17041 tcgtgtaatt tttctagatc atcagctgct atagcgatat gaccatagcc gtctcctaga
    17101 tcatacgcac catgatcata gttgtaagtc aactctaatt catagtcatc cccaggaagt
    17161 gtcaaataaa caagtgtaaa tttgttttct ggaaaatcac ggcggcggct ttcttcaaaa
    17221 ccaaatgcct tttgataaaa ttcgattgat gcttcaagat ctttcactcg aacacatgtg
    17281 tgagccattt tcatagattc atctctcctt ttccttttac tcaatcataa caaaaagaag
    17341 taaggaaata gttgatttgt gcttgttcat gagaaatttc tcatgtaaaa tggatagaaa
    17401 ataaaactgt taaggtggaa actattcatg gataaaccaa tttttggtga aaaaaagcaa
    17461 tttgctgatt atcaaacccg ttatgcagca tatattgtca tagaaagaga tcagcagatt
    17521 gcagtaatcg aggctccaaa tggtgctttt tttcttcctg gcggggaaat tgaaggagaa
    17581 gagacgaaag aagaagcgat tgtccgtgag ctgatagaag aaatgggaat tgtggcagaa
    17641 atttcttctt atctgggaga agctgatgag tatttttact cgaattatcg tgcaacttat
    17701 tattataatc caggatattt ctttgttgct gattcttgga agcgtatagg agaaccaact
    17761 gaaaagacca ataaaatttg gtgggtgagc cctcaagaag cgcttgtgaa attgaaacgt
    17821 ggtagccacc gatgggcagt cgagagatgg atcgaaaaaa ataaaaactg aaagaaagcg
    17881 agtagatcag ctttctctca gtttttttat ttattacagt acatattttt tgattgcttc
    17941 agctacaccg tgctcgtcgt ttgatgaagt gatgacattt gctgcttctt tgacaagaga
    18001 aacggcattt cccattgcta ctcctagacc agcatattca atcatggata agtcgttctc
    18061 gttatctccg atagccatga tttcatcttg atcaatacca aggtgctgtg cgagattcgc
    18121 aactgccgca cctttacttg cttctttatt tagtacttcg aagtaatagg gcgcactttt
    18181 gaccgttgtg tatttatcac ggaaagtttg cggtaaacgc gcaattgctg catctaaaat
    18241 ttctggttcg tcgatcatca tcattttgac gatgttcatg tctggtgtca tttcttcagg
    18301 tgttcgatat tttagcggca tcttgactaa acttgcttcg tggatcgtat aagcgctgat
    18361 atctcgatta ggcgtgtaga tcgctttgtc atcgatcgaa tggagatgac tgccgacacg
    18421 gcgtgccatc acttcgatct ctaggaaatc ttcatgtgtc agtccgtgac gggcgatgat
    18481 tttacctgat ttcgtttgtt gtacgagtgc cccgttataa gtaataacgt aatcattatc
    18541 ttgaaaaagg ttcaactcgt ttaactgttc ctggacacct ggtaagggac ggccagtgca
    18601 taaaacgatc gaaacacctt ttgcaacagc agcggcaatc gcttctttta cttcttttgt
    18661 tacttctctt ttctcattta ataaagtacc atcgatgtcg atagcgacta gtttgataga
    18721 cataatttcc tccaatatat tttaatttat ttcaatcaat gcgccattac ggatatggct
    18781 ggcaaattct tgataagttt cgtcaaataa atcataatga tcacgcaagg acggatcaac
    18841 catttctttt ggaaagaaaa atcgctcatc tccttgttct tgtcccgcta atgcagcaac
    18901 aagctgacta acctgtgata attctatcaa agttccgtca tttcgcaaaa tctcgatttg
    18961 tgtgcgatgt ctgccttgtt ctgggcgata aaaatcataa ggtagatcgt agctagaatt
    19021 cacagcagtg taataaacag gattatatcc gaccttttct actaacaaag tgagttcttg
    19081 gactaatttt gaatcccggt tgccagaaaa agtagcagat ttcagtggtt tacgattcaa
    19141 aaaacgttta gctaaatcat ttaaaatagg atcagcagat tcagaccatt gagtaaagta
    19201 agtgcccaag accccatcat caagtttgag gtattcttct aaagtaaagc ttccgtcaag
    19261 aaatggcaga agtaattgag aatggagttc aaaactgctg gcatcttctt gatacaactc
    19321 gtgtgcgcga tgaagcagat gctccaaaat tacttccata ccacgggaaa caggatggaa
    19381 gtacacttgc acatacattt gatatcggct aacgatataa tcttccactg catgcatgcc
    19441 actcatggaa aaagcgatcc cgccttcata aggacgaatc acacgtaata ttcgggtaag
    19501 atcaaatgtt ccatattctg ttccagtgaa ataagcatcc cgaagcaaat agtccattcg
    19561 atctgcatcg atctgactag aaatcatttg gacaacttgt gggttggggt aagttttttg
    19621 gatcacacta gctacctttt caggaaaacc ttcttctact cggttaagaa tctgatacac
    19681 ttctgtttct ggagaagtga tgatctctac agtgatggct tcatgattcg tatggaagat
    19741 atgttcaaat gtatgagagt aaggaccatg accgacatca tgcaacagtg ccgcacataa
    19801 agtcaccagc cgttcctgat catcccagcc tccgttgcct attttttctt ttgaaaaatt
    19861 tcgagaaaag atatcgcaga ttcgtcttga aatctcataa acgcctaatg aatgagtaaa
    19921 acggctatgt tctgctccgt gaaaagtgaa agaagaagtg cctaattgtt taatgcgtcg
    19981 tagacgttgg acttctttcg aattgatcaa atctaagatt acttgatgct ggacatggat
    20041 atagttatgg actggatcac gaaaaacttt ttccataggc agcatttgat atttataagg
    20101 ggttgtcata atgtagctcc tttatgttat tacgttgttc cattctctgg atttggttgt
    20161 tccattgctc cagctggatt tcttttttta gccagtcggt agaatcctgt aaatcacttg
    20221 cagaatacag cttttcaaaa gcttttgcaa atgcttcttt gacttctttt acaaaaaggg
    20281 gttggtcaag cagttcttca agtgttgcca ttgtagcagg atccactgca ggatagccat
    20341 ttgtaccaaa gtcttctttt aaagcagatt gataaaatcg cttcatgact tgcccgcgtt
    20401 tttcctgatt accgttgaca cttaagtaca tcataacaga aatcccattt ttgatccgac
    20461 gctgagcgat accggcaaat tttttgccat ggatgcttaa atcataagtt ccaggacaat
    20521 aagaatgggt gatttcgaat gcttgtatcg gtgcctttgg aaaagcgtat ttagtcaata
    20581 ggagcatttg ctcgtaagcg tcatctatgg ttattttttt tgtgtcactt tgggggaaaa
    20641 tcaaagaaat attcaaaatt ccttcatctg atacgatccc taatccacct gaatttctga
    20701 tcactggagc gtaacctgca tctttcagtg tttggatccc gtcacttaga aaaggagttc
    20761 gaacatcctt catacctaag atgactgtgc agtcatattg ccagaaatgt aaaaagattt
    20821 gctggtgttc tttagaatat tccgttaata tatctgttaa tgcaaaaggg gaaaagtcgt
    20881 ttttttgata aatgtgctga tctagtcgaa tcgcagggtt cattcaaccg gctcctttgt
    20941 ataaattcat attttctaca atattatact ctaaaatcaa agagttgttt tggaaaaaag
    21001 gttttctgta aaaatggaca agttggttga caaaacaaaa gaaactagga acaatgtagc
    21061 tatgagaagt aaaggagaat gaataatgga attatcacaa ggaacaccga tttcaatcaa
    21121 attgcgtaca aaagtaaaac agcaagggga agtgcaagat ttttattttg atttgaaagg
    21181 gcaaatggtg acaattggcg atacgctgta catacgttat aaagagattc aggaggagac
    21241 gggcgatgag attcctgtaa cgatcaaatt agttccagat ggtcatgtac agctgatccg
    21301 tgcaggagaa atgcggatgc gtttgaaatt tggctataaa gaacggttag aaacatccta
    21361 tcgaacacca tacggtatga tccagattgc tacttttacg aaagaactgc atgttagttt
    21421 gaaagaccgt cccacaggag ggaaggttcg aatcgattat gatctgttca tgggaccgga
    21481 aaaaatcggc gaatattatt tgaccttgga ttttacagcg taaatataaa agaaaagttt
    21541 gattttttgt gtctgatttt gtatgataag gagtagactg tgaaaggacg tgtcctgatt
    21601 ggaaattagt gtatttgaag gtgcaaacaa aagcgaatta tcaatgatcg aagtagcaca
    21661 cgcgatctta gaacaacgtg gcgatgtcat ggatttttct gatttagcta accagatcca
    21721 aaactatctt gggaaatcag acagtgaaat tcgtgattca ctcgcacaat tttatactga
    21781 cttgaatatt gacggcagct ttatctcatt aggggataat cgttggggct tgcgttcatg
    21841 gtatgctatc gattcgatcg atgaagaagt aaaccatgga atggacgaag aggatgaaga
    21901 tactccacgt cgccgtaaac gcaagaaagt caacgccttt atcaatgatg atgaagacgc
    21961 gatcgattac aatgacgatg acccagaaga tacagatctg acagaagaag atgacgatga
    22021 tctgtttgat gacgatgatg atgaagatga agaaatcgct gcttataatt ctgacttgca
    22081 agaaatcgga gcagatgacc cgacagatga tgaagaagac ttgccaggaa atatcgaaga
    22141 agatttaagt atcatagacg aagacgatga tgatgaagat tatgaagagg aagaattttc
    22201 tgactctgaa aaagaataaa cattattttc ttacgagagg ttgtgacaga gacgatcagc
    22261 ctatcagaat aaggaggtgt gacacgattt ttgtcacacc ttcttttttg tatataaaaa
    22321 tcccaagtaa atacataaaa aataaaaaaa ttgaaacttt tagcgcacct tgtacgtcat
    22381 attaagtgag gcagaaagga gtggagaatg atttttactg gatataagaa aaaacggcag
    22441 atcgaaaaat accgtcacct gctgaatgga ctcatcgaaa ctgattatca aaaaatgttc
    22501 cgtatcacga tgaattacgt acatgataaa gaagaggcct tagatgtgat gcaagatagt
    22561 tttcataaag ccctgaacta ttttgaaaaa gaaaaagaga tcgagcattt tagtgcatgg
    22621 ttttatcgga tattgatccg cacggcatta gatagttggc gcagacaaaa aaggacgcct
    22681 gtggacttat ttgaaattca agatatcccc caacagttac ctttagaaac ttccgttgca
    22741 gagctccata tgattttaga taaaatagac agtccggaaa aagagattct gatcctctac
    22801 ttttttgaag gatttcgttt gaaagaaatt gcgactatct tggatatgaa tgaaaacaca
    22861 gttaaaacga aaatgtaccg ctcattgaat gctttacgtc aaatcctaga atgaaggaga
    22921 gaagagtgcc atgtattccc aaaaagaaaa tttaaaaaaa ctaaagaaaa cttataaaga
    22981 acaagcaatt cccaaagggc ttaaagagga gatccgccag cgttttatta tcgaagagca
    23041 atcatttata aaagcaaagc ggagaaagag acgtctccaa gggttcggag tatctttggc
    23101 tatcgtaatg attacaacaa gtagccttct ttttaatagt caagttcgaa gctttgcaga
    23161 agatttaccc atcttaggat cagtcattga attgatctta ggcgaacgct ttactgatcg
    23221 atctgaaaaa atcgatattc aggtaccgaa gatcaataca caaaatgaga aagaaaataa
    23281 aacaattcat ggattaaatc aaaaatactt tcgcgaagga caagcagatt ttgaaaaagc
    23341 tgaaaaagaa tatggaaatt ttgaaacgga tcattaccaa gttttgggag attatcagaa
    23401 aatcgtagac gataaccggt ttctcgtgat tgaaaggcag atcacccaaa cagcagcaga
    23461 tagccatgtt gaaaaaagat acgacacaat cgacaagaaa aacagtgtcc agctctcact
    23521 tccactttta ttcaaagatg acacctatct atctgttttg acaaaagaag tcaaacggca
    23581 gatggccgaa caagtcaagg aagatccatc taagtactat tggactgagc aagatattca
    23641 agaagggacg atagaaaaac caacacttgt tacgcctaca cgaagttttt atttgaacaa
    23701 agagcatcaa ttagttttga ctttttctca atacgaaatt gctcctggtt atatgggtac
    23761 accagaattt gtcattccta agtccgtgac aaaaacgatt ttggcatcgg aagattattt
    23821 ggatcattag acgagaagta gttgcgacta gcagtttcaa ttttcaagta agtacaagta
    23881 aataataaga agagaaaaag agaaagaaga gatatagtga aaagaaatta tttagttatc
    23941 agtattattg ctttatccgt gcttttgttt ttcgaaatta cttcggtggc ctccttgatc
    24001 accgaagtaa aaggacaaac acactcttcg gagcattcgt cacaatcttt caaacaatca
    24061 gaacaatcaa ccattaaaag ccaatcaact gaaacagcta acgtcaaaga agccattcaa
    24121 gaatcagcgg aaaaggtaca aagtcagtca tcacaatcaa cacaagacag tacaaaaacg
    24181 agccgagatc cggctgtcaa aagcgtcgca atcagctttg atgatggacc aggagcgacc
    24241 acaacaccgc agcttctgcg aatcttaaaa gaaaaaaacg tgcatgccac ttttttcgtc
    24301 ttaggagaaa atacggcgca gcatcctgaa atcgtgaagc agacagctga agcagggcac
    24361 gagattggca attacacata cgatcatcag aatctggcca ctctttctgc ccagtcgatg
    24421 acggaggaag tgacgaaagc agacactgag atcaaaaaag tcactggcaa aacccccact
    24481 tttgttcgtc cgccctatgg ttctgtcacg aatgtaggag caacgatcat ccagcgaccg
    24541 atcatcgaat ggtctgttga ttcagaagat tggaagacaa gaaatcctga tttgattttg
    24601 cagaagatcc aagcaacagt atacgatggg gcaattattt tattccatga tatctatcct
    24661 gaaacgattc gtgccgttcc tcaagtgatc gattatctga aagagcaagg gtatcgcatc
    24721 acgacagttg gggatttatt agggcatcca acggctgtcg agaactatta tggcagaaac
    24781 gatcatcggc cagttcagta agtgagacaa gtatctttaa taaataacac attttaataa
    24841 gtagttgaac acataactac cttacttgca aaggcttaac aatatctata caggtacaac
    24901 aaaaaactgt ccaccaattt tctttggcgg acagttttca cttaaaaata aagaagcaac
    24961 tattcgtaaa ttatgctaaa atagcagtag aacgcgtcct gagggaatcg aacccccgtc
    25021 tcaagaaccg gaatcttacg tgatatccac tacactaagg acgcaagcac tgggataatt
    25081 gtaactaaac agataaaaaa ttacaagggg attggacaaa aaaatgaaat ttgagcaaaa
    25141 tttttcacaa aaacagcagc agacacagaa actagccatg acgcaacagt tgcaacagtc
    25201 catccaagtt ttacaatata acagtgagga gctgttggca ttcgttgaga atcaagcaat
    25261 ggaaaatcca ttggtggaag ttgttgagcc ggaatggcag ccagattaca taaaagcttc
    25321 ttcatcttct tatgaaggag aagagacaaa ttacctaaat cagattcctg atacaaaagg
    25381 gtctttattt gattcattga tcgaacaagt ccatttgaat taccgagata cttttttgag
    25441 gaaaatcgtt ctttatcttg tagaatacat cgatttgaac ggatttttga cgattagttt
    25501 agaagaagcc ggaaaagaga ttggagctac gcctatccaa atgctcgatg cgttgactct
    25561 gattcagcaa ttagaaccag ctggagtagg tgcacgtagt ttgcaagaat gtctcatgct
    25621 tcaaacagaa cgagatgatt atgcgccgga attagcttat atcgtgttgg aagaatgttt
    25681 tgaggaactg gtggagcgaa aatggaaaga aatcgcacaa cgtttttctg ttgatctaca
    25741 tgctgttcag cagatattcg actatttaca aacgttgagt ccaagccctg gccggatttt
    25801 cgaccgtagc agcgaattgt acattattcc tgatgtccgg gtattagtgg acgacgataa
    25861 aaatgtacaa gttatctcaa accgaaaaaa tcagccaaat atacgctttc aagagagtta
    25921 cttcaaacaa atgtcacaac aagcagataa agaaactgaa aattatttaa aagaacggaa
    25981 acaggaattc gaatggttga agaaaacgat cctacaacgt ggggatacaa ttttgcgggt
    26041 tgctcaagtc attgtttccc ggcaaaaagc tttctttatc gacaaggaac gtccaatcaa
    26101 gcctcttacg ttaaaggaag ttgcaactga gatagatgtg catgaatcca cggtcagtcg
    26161 tgcagtcaac gggaaatatt tggaaacaga tttcggtgta tttgaattaa aaaaattttt
    26221 cactacacga attcctacga atagtacaga acagacagaa gacctttcag cagatacagc
    26281 gaagaaaaag ctgcaggaat tagtcgatca agaagacaaa aacaagccgt tgtcggacca
    26341 gaaattggtt gaattgctga aaaaagatga gatagcgatc tcaagacgaa cagtagcaaa
    26401 atatcgtgat ttattaggaa tcccgagttc atcaaaaaga aaacgttatg ataactaatc
    26461 agtcaaaaga ctagaaaaag tatttcactt tttctagtct ttttagttga aaaacgagag
    26521 cgaaactgtt agacttacag tcgtgaggtt gagatttccc tttattgatg tgaaattcga
    26581 atagttaatt tcttttttta tcgtatatgg gtcgttttaa gtctacattg gacgtaaagt
    26641 gtccaactaa ggagatcgct atgctggatg aaataaaaat gattgaatct gttgcaccag
    26701 atattatcga agtgttgcaa gaacgctata aaattttacg aaatatctat tggatgcagc
    26761 cgattgggcg tcgaagttta tcggaaagta tggggatcac agaacgagtc ttacgaacag
    26821 aaacagacct tttgaaaaat ctgaatttga tcgacacctc aaaaagcggt atgacgctga
    26881 caactaaggg cgaagaagtt tatcaaagcc ttgaaaactt catggatcag cttttaggta
    26941 cgcatcaaac cgaacaacag ttggcagaat attttggtaa ccaacgctgt atcgttgttt
    27001 caggaaacag cgaagagcag accaaagtgg ctgatgcatt cggcgaagcg ctgagcgaag
    27061 ccttagaccg actacttcca gaaggcgaga atatcatcgc tgtgatggga ggaactacta
    27121 tggctgtggt agccgaacaa ttgtctaatc tggaaaataa gaaacggcat aacctgtttg
    27181 tccctgcaag aggcgggatt ggtgaagcga taactgtaca ggcaaattct gtcagtgcaa
    27241 gaatggctgc taaagcaaac ggtaaccacc gcgcacttta tgttccggaa caattaagtc
    27301 tggcaactta caattcttta ctcaatgagc catctatcca agaagtctta aacttgatta
    27361 gtgaagcgaa ttgtgttatt catagtattg ggcgtgcatt acacatggca gcacgtcgta
    27421 agatgactga aaaagaatta gtcatgctga aacaagcaaa tgctgttgcg gaatcttttg
    27481 gctacttttt caatgaaaaa ggtgaagtcg tttataaggt ccctagaatc ggcatagaat
    27541 tgcaagattt ggaaaaagtc ccgatcatca tggcaatcgc gggcggaaaa tcaaaagcta
    27601 aagcaattcg agcttatatg aaaaatgcac caaaacaaac gtggctcatc actgatgaag
    27661 ctgctgcaaa tgagatttta aaaggggtaa ccctttaaaa taaatatttt tttgattttc
    27721 ataaggagga aatcttaaat gacagttaaa gtaggtatta atggttttgg acgtattgga
    27781 cgtctagcat tccgtcgtat ccaagatgta gatggaatcg aagtagtagc aatcaacgac
    27841 ttgacagatg ctaaaatgtt ggcacacttg ttaaaatacg acacaactca aggacgtttc
    27901 aacggaacag ttgaagttca tgaaggttca ttcaacgtaa acggaaaaga agttaaagta
    27961 ttagctaacc gcaacccaga agaattacca tggggcgaac taggcgtaga tatcgttcta
    28021 gaatgtactg gtttcttcac ttctaaatca gcagctgaaa aacatttaac agctggtgct
    28081 aaacgcgttg ttatctctgc tcctggcgga aacgatgttc caacaatcgt ttataacaca
    28141 aaccacgaaa cattaactgg taaagaaaca gttatctcag gtgcttcatg tactactaac
    28201 tgtttagctc ctatggctaa aacattgaac gacaaatttg gtgttgttga aggattaatg
    28261 acaactatcc acgcttacac aggtgaccaa atgactctag acggacctca tcctaaaggt
    28321 gacttccgcc gtgcacgcgc tgctgctgca aacatcgttc ctaactcaac aggtgctgct
    28381 aaagctatcg gtttagtaat tcccgaattg aacggtaaat tagacggagc tgctcaacgt
    28441 gttcctgtac caacaggttc attaacagaa ttagtaacag ttcttgaaaa agaagtaact
    28501 gttgacgaaa tcaatgcagc aatgaaagaa gcttcaaacg aatcttacgg atacaacaca
    28561 gacgaaatcg tttcttcaga tatcgttggt atgacttacg gttcattatt tgatgctaca
    28621 caaactaaag taatgacagt tggcgacaaa caattagtta aaactgttgc ttggtacgac
    28681 aacgaaatgt catacactgc acaattagta cgtactttag aatacttcgc taacttataa
    28741 gatagacaaa cgtacaagtg taaattatag acatgtacat ttaaaagcgg ggaagcaatc
    28801 gcgcttcttc cgcttttttt gataataagt ttattcagga ggaaataaaa tggctaagaa
    28861 aacagtgaaa gatatcgatt taaaagacaa aaaagttctt gtccgtgttg acttcaacgt
    28921 tcctttgaaa gacggcgtga tcactgacga cactcgtatc aaagcagcat tgccaacaat
    28981 caactacgtt ctagaacaag gcggaaaagc aatccttttc tctcaccttg gacgtgtaaa
    29041 aacagaagaa gataaagaag gaaaatcttt agctccagtt gcaaaacgtc taggcgaatt
    29101 attaggtaaa gaagtaacat tcgtacctga aactcgcgga gaacaattag aagaagcaat
    29161 ccgcaacatg aatgacggcg acgttgtcgt attcgaaaat acacgatttg aagatattga
    29221 cggtaaaaaa gaaagcaaaa atgatacaga actaggtaaa tactgggctt cattaggcga
    29281 tgtatttgtt aacgatgctt tcggtacagc tcaccgtgca catgcttcta acgtaggtat
    29341 cgcttcaact ggtatcccaa cagttgctgg attcttgatg gaaaaagaaa tcaagttcat
    29401 cggtgaagca gtagaagaac caaaacgacc aatgattgca atccttggtg gcgcaaaagt
    29461 ttctgataaa atcggcgtaa tcgaaaactt gattcctaaa gcagataaaa tcttgatcgg
    29521 tggcggaatg acttacacat tctacgaagc aaaaggaatc aagatcggta actctctagt
    29581 agaagctgat aaagtggaac tagcaaaaga attaatcgaa aaagcaggcg acaaacttgt
    29641 cttgccaatc gacaatgtct gtgcaccaga attttcaaat gatgttgaaa cacaagtaat
    29701 cgaaggagac attcctgatg gtttgatggc tttagacatc ggcccagcat cagtaaaatt
    29761 atttgctgat acattacaag gtgcaaaaac agttgtttgg aacggaccta tgggtgtatt
    29821 tgaaatgagt aactttgcta aaggtacaat cggtgtttgt gaagcaatcg ctaacttaga
    29881 aggcgcaaca acaatcatcg gtggcggaga ctcagccgca gcagcagaac aattaggatt
    29941 tgctgacaaa ttcacacaca tctcaacagg tggcggcgca agcttggaat tgcttgaagg
    30001 taaagaatta ccaggactag cagcaatcaa cgataaataa acgaccaagt ttgctcaatt
    30061 ctgacgagta atcgaacaaa aggtgaaggg agttttcatg actccctagc catttttcaa
    30121 taaattaagg agtgtgttcc tcaatgcgta aacctattat cgcaggtaac tggaaaatga
    30181 acaaaactgc atcagaagca aaagaatttg ctgaagcagt aaaaaacaaa atcccttcaa
    30241 atgacaaagt tgattcagtc atcggatctc ctgcattatt cttacaagaa ttaatgacat
    30301 cagctgaagg tacagaacta aaaatctcag cacaaaactg ctactgggaa aactcaggtg
    30361 cgttcactgg tgaaacttca ccagcagctc ttgctgatct aggtgttcat tatgtgatca
    30421 tcggacattc agaacgtcgt gaatatttcc atgaaacaga cgaagacatc aataaaaaag
    30481 cgaaagctat ctttgcaaat ggtatgacac caatcctatg ctgcggcgaa tctttagaaa
    30541 cctatgaagc aggcaaaact gctgaatgga tcgaaggaca aattacagct ggtttagctg
    30601 atctttcagc tgaacaggtg tcaaacatgg ttattgctta tgaaccaatc tgggcaatcg
    30661 gtactggtaa atcagctgac gcacaaatcg ctgacgaaat ttgtggagtt gtacgtcaaa
    30721 cagttgaaaa actttatgga aaagaagtat cagaagcagt tcgtatccaa tacggcggtt
    30781 ctgtaaaacc agaaaatatt gctgaataca tggcaaaaga aaatgttgac ggtgctttag
    30841 tcggtggcgc aagcttgcaa gcagattcat tcttgtcatt gttagacgct gtaaaataat
    30901 tgttgaaaat ttgcgaaaaa tgcaagaaat gtttgcacta atgagcaaaa ttaactaaaa
    30961 tcgtatatga gggaaatccc ttaggaaaaa acaaactcaa aggagagaca aaacatgtca
    31021 attattactg atgtttacgc tcgcgagatc ttagactcac gtggtaaccc aacaatcgaa
    31081 gtagaagtat acacagaaag cggagctttt ggccgcggaa tggttccttc aggtgcttca
    31141 actggtgaat acgaagcagt tgaattacgt gacggagaca aagctcgtta tggcggtaaa
    31201 ggtgtaacta aagctgtcga caacgtaaac aacatcattg ctgaagcaat cattggctac
    31261 gatgttcgtg accaaatggc tatcgacaaa gctatgatcg ctttagacgg aactcctaac
    31321 aaaggtaaat taggtgcgaa cgctatttta ggtgtttcta tcgctgttgc acgtgcagct
    31381 gctgactacc tagaagtacc tttataccac tacctaggcg gattcaacac aaaagtattg
    31441 ccaacaccaa tgatgaacat catcaacggc ggatcacatg ctgataactc aatcgacttc
    31501 caagaattca tgatcatgcc tgttggcgct ccaacattca aagaagctct acgtatgggt
    31561 gctgaagtat tccacgcatt agcttcaatc ttgaaagctc gcggattagc aacttctgtt
    31621 ggtgacgaag gtggatttgc tccaaacctt ggttcaaacg aagaaggttt tgaagtaatc
    31681 atcgaagcaa tcgaaaaagc tggctatgta cctggtaaag acgttgttct tgctatggat
    31741 gctgcttctt cagaattcta cgacaaagaa aaaggtgttt acgtactagc tgactcaggc
    31801 gaaggcgaaa aaacaactga cgaaatgatc aaattctacg aagaattagt ttctaaatat
    31861 ccaatcatct caatcgaaga tggattagac gaaaacgact gggacggatt caagaaatta
    31921 actgacgtat taggcgacaa agttcaatta gttggtgacg acttgttcgt aacaaacact
    31981 caaaaattat ctgaaggtat cgaaaaagga attgctaact caatccttat caaagtgaac
    32041 caaatcggta cattaacaga aactttcgaa gctatcgaaa tggctaaaga agctggctac
    32101 acagcagttg tatctcaccg ttctggtgaa acagaagatt caacaatctc tgatatcgct
    32161 gttgcaacaa acgctggcca aatcaaaact ggttctctat cacgtactga ccgtattgct
    32221 aaatacaacc aattactacg tatcgaagac caacttggtg aagttgcaga atacaaaggt
    32281 ttgaaatctt tctacaactt aaaaaacaaa taattctttt ctaatgaaga tacatgatcg
    32341 actattgaaa gatagtcgag tatgatcact tagttaagta atcgaactct ctacttgctg
    32401 aaatatcagc aggtagagag tttttttgca actagcttct gtatatgatg tttacaaaga
    32461 atggtacaag aaaagatcat ccttgaaaaa ggaaagctaa caataactag catcatataa
    32521 gagcttttaa ggatagaaca gtagaatagg aatctatggg caagtcctct cgtataaata
    32581 aaataggagg gaagtagcag catatttttc ataaagtggc tctctttctt catttttact
    32641 ttggttgctc ctatttgaaa attcgagcac actcaaatac aataaaaaga aatggcaagg
    32701 gagaggatta gatgaaaaaa gaagaaaaaa tcgcgatttt acaagagatt atccgaatta
    32761 aatcagtgaa tggaaacgaa ggtgaagtag cagcctattt gaataagctt ttggcaaagc
    32821 atgacataac aggagagatt gtttcttaca gagatggtag agataatttg attgctcgtt
    32881 accaaaaggg ccaatcagga aaagtgttag gcctatctgg acatatggat gtcgtggcgg
    32941 ctggtgatga atcgtcttgg acctatgcac cctttgcagc agaaatccat gggaaccgtt
    33001 tgtacggacg tggtgctaca gatatgaaga gtggcttggc agcaatggtg attgccatga
    33061 tcgaactgaa agagtcagga aaaccattta acggaacagt caaattatta gccactgtcg
    33121 gagaagaagt gggtgaacta ggtggggaac agctcacgaa agcaggctat gtagatgact
    33181 tagatgcctt gatcatcgga gagccaacca attacagttt gatgtatacg cacatgggat
    33241 caatcaacta tacagtcacc tcgcacggaa aagaagcgca tagctctatg ccagaccaag
    33301 gttataatgc aatcaatcac ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc
    33361 acctcgctga aacaatcgag aatcctgtcc taggaaaaac aatccataat gttacattga
    33421 tcagtggcgg gaatcaagtc aacagcatcc caagccatgc gcagctccaa gggaacattc
    33481 gatcgattcc agaataccca aatgataaaa tcattgcatt gctgcaatca atcgtcaatg
    33541 aattgaatca agagacagac tatcatttgg aattgatgat cgattacaac aaaatacctg
    33601 tcaaagctga tccagattct cctttgattc attgcattca gcaacaattc agccagccat
    33661 tacctttagt tggagcggca gcaacaacgg atgcagccga atttacgaaa gctaaccatt
    33721 ccttcgactt tgtcgtcttt gggcctggtg tcgttacttt gcctcatcaa gtagatgagt
    33781 atgttgaaat cgataattat ttggatatga tcgaaaaata tcaaggaatt attttatcct
    33841 acttagcgta agattttttt aat
//
LOCUS       DAIGTA010000027        33761 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.027, whole genome shotgun sequence.
ACCESSION   DAIGTA010000027 DAIGTA010000000
VERSION     DAIGTA010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.027"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            195..827
                     /locus_tag="NOB43_001390"
     CDS             195..827
                     /locus_tag="NOB43_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982255.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(961..1086)
                     /locus_tag="NOB43_001391"
     CDS             complement(961..1086)
                     /locus_tag="NOB43_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0982256.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1220..2113)
                     /locus_tag="NOB43_001392"
     CDS             complement(1220..2113)
                     /locus_tag="NOB43_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HCI0982257.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(2295..3221)
                     /locus_tag="NOB43_001393"
     CDS             complement(2295..3221)
                     /locus_tag="NOB43_001393"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HCI0982258.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3306..4067)
                     /gene="pflA"
                     /locus_tag="NOB43_001394"
     CDS             complement(3306..4067)
                     /gene="pflA"
                     /locus_tag="NOB43_001394"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HCI0982259.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4311..6542)
                     /gene="pflB"
                     /locus_tag="NOB43_001395"
     CDS             complement(4311..6542)
                     /gene="pflB"
                     /locus_tag="NOB43_001395"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCI0982260.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6819..9269)
                     /gene="parC"
                     /locus_tag="NOB43_001396"
     CDS             complement(6819..9269)
                     /gene="parC"
                     /locus_tag="NOB43_001396"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCI0982261.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9281..11326)
                     /gene="parE"
                     /locus_tag="NOB43_001397"
     CDS             complement(9281..11326)
                     /gene="parE"
                     /locus_tag="NOB43_001397"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCI0982262.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11492..11926)
                     /locus_tag="NOB43_001398"
     CDS             complement(11492..11926)
                     /locus_tag="NOB43_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCI0982263.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            12053..12691
                     /gene="plsY"
                     /locus_tag="NOB43_001399"
     CDS             12053..12691
                     /gene="plsY"
                     /locus_tag="NOB43_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCI0982264.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGLNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12823..13698)
                     /locus_tag="NOB43_001400"
     CDS             complement(12823..13698)
                     /locus_tag="NOB43_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCI0982265.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13780..14571)
                     /gene="codY"
                     /locus_tag="NOB43_001401"
     CDS             complement(13780..14571)
                     /gene="codY"
                     /locus_tag="NOB43_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HCI0982266.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14589..15989)
                     /gene="hslU"
                     /locus_tag="NOB43_001402"
     CDS             complement(14589..15989)
                     /gene="hslU"
                     /locus_tag="NOB43_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HCI0982267.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(16003..16551)
                     /gene="hslV"
                     /locus_tag="NOB43_001403"
     CDS             complement(16003..16551)
                     /gene="hslV"
                     /locus_tag="NOB43_001403"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HCI0982268.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16588..17493)
                     /gene="xerC"
                     /locus_tag="NOB43_001404"
     CDS             complement(16588..17493)
                     /gene="xerC"
                     /locus_tag="NOB43_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCI0982269.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17691..19067)
                     /gene="trmFO"
                     /locus_tag="NOB43_001405"
     CDS             complement(17691..19067)
                     /gene="trmFO"
                     /locus_tag="NOB43_001405"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HCI0982270.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(19036..21114)
                     /gene="topA"
                     /locus_tag="NOB43_001406"
     CDS             complement(19036..21114)
                     /gene="topA"
                     /locus_tag="NOB43_001406"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCI0982271.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21236..22093)
                     /gene="dprA"
                     /locus_tag="NOB43_001407"
     CDS             complement(21236..22093)
                     /gene="dprA"
                     /locus_tag="NOB43_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCI0982272.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(22149..22916)
                     /locus_tag="NOB43_001408"
     CDS             complement(22149..22916)
                     /locus_tag="NOB43_001408"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCI0982273.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22909..23769)
                     /gene="ylqF"
                     /locus_tag="NOB43_001409"
     CDS             complement(22909..23769)
                     /gene="ylqF"
                     /locus_tag="NOB43_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HCI0982274.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            24029..24427
                     /locus_tag="NOB43_001410"
     CDS             24029..24427
                     /locus_tag="NOB43_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0982275.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24706..25206
                     /locus_tag="NOB43_001411"
     CDS             24706..25206
                     /locus_tag="NOB43_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI0982276.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(25289..25840)
                     /gene="lepB"
                     /locus_tag="NOB43_001412"
     CDS             complement(25289..25840)
                     /gene="lepB"
                     /locus_tag="NOB43_001412"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0982277.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25992..26219)
                     /locus_tag="NOB43_001413"
     CDS             complement(25992..26219)
                     /locus_tag="NOB43_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HCI0982278.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26216..26734)
                     /gene="msrA"
                     /locus_tag="NOB43_001414"
     CDS             complement(26216..26734)
                     /gene="msrA"
                     /locus_tag="NOB43_001414"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0982279.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(26754..27467)
                     /locus_tag="NOB43_001415"
     CDS             complement(26754..27467)
                     /locus_tag="NOB43_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HCI0982280.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27470..28366)
                     /locus_tag="NOB43_001416"
     CDS             complement(27470..28366)
                     /locus_tag="NOB43_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0982281.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28524..29366)
                     /locus_tag="NOB43_001417"
     CDS             complement(28524..29366)
                     /locus_tag="NOB43_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0982282.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29498..30151
                     /locus_tag="NOB43_001418"
     CDS             29498..30151
                     /locus_tag="NOB43_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCI0982283.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30214..30741)
                     /locus_tag="NOB43_001419"
     CDS             complement(30214..30741)
                     /locus_tag="NOB43_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0982284.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(30761..31708)
                     /locus_tag="NOB43_001420"
     CDS             complement(30761..31708)
                     /locus_tag="NOB43_001420"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCI0982285.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(31720..33606)
                     /locus_tag="NOB43_001421"
     CDS             complement(31720..33606)
                     /locus_tag="NOB43_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0982286.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
BASE COUNT         8906 a         7071 c         5815 g        11969 t
ORIGIN      
        1 catgatgaat ggatttattc ttcaagaaaa tacatcaatt ttgataagta gaaattgtaa
       61 aaacattgta tagcatttta cacaggagtc tggacttgac ttttttattt attattttga
      121 ttaaaaaaca tcgacatata ctcatcaatt tgttattata ctttatatac ttatcaattt
      181 aatttggaga tattatggaa attcaacgta gaaccactaa ttttttacat ttaggctctt
      241 tttttgcaac tttgacgatc ttattttttc tatgttattc ataccttaag acctcacatg
      301 cgccttctag tgcattaggc tggttgcttt tggatcattc tgatatcaca gaagccgaag
      361 aaaatccgtt ttttttgatt ttgtcttctc tttgcggctt actgttttct gtttatttcg
      421 gtgcctattt ttttcatcga catcctggta cgttaaacga agcttcaagc gtattgattg
      481 catttaaaac gttttctttt ttagcaattc ttttttattc gtttaatcac aatacgcttt
      541 tcttctttat catgaatggt ttagtcgtga ttttatccat ttttacttat tttatttttt
      601 cactcatttt tagccaattg aaatgtccgc tcttctttcg attagttcct gtcacctgtt
      661 ttatttacag cttgttttcc ttttttgtcc ttgctttaat gccactgacc aacccttcga
      721 cgatccaagt cgcaggaaat ctgttggata tgctcttcat cgtcagtcta ggtgtattta
      781 tgtggcaaag aaaaaacaaa caaaataaaa agcattttga agcctgacta ttacgacttc
      841 ataaatgctt ttttagtttt aaacacttca atctaaaaga ataacccaag attggataaa
      901 ttattaatga ctcgccattc gtttcttagt gattctggat tatcaaatgg acttcctaat
      961 ctaatcagct agttcttccc ataaaatgcc atacttgact gaatcataat attgattatt
     1021 taaaaatcta acttttctta tcactacttc ctttgtcatt ccacatttct caccattttt
     1081 ttgcattcct ttgtttccag accatgtagt gaatctaata ggtggtagat aggcaaaata
     1141 ctcaaataat tcttttaacc ataaaggaag agaaaggctc ctcctgcaag agtcagtata
     1201 atttttgctt actgctctct taggttttac tcactaaaac tgttccatat tctttgatat
     1261 aagaaaatgc atgcggtata aatttcttgc tcagctcaga aaagatttgt cgtttaagaa
     1321 aggccatttc ctccattgtc aatgaaggat ccaatgttgg taattcaatc tcaaaattgt
     1381 ttttttcgac aataggtaat tctaatgtga atgattcttc ttcctttata gtattcgtca
     1441 caagtagaga ctgatggaaa atactaggcc ggcgattttt atatttattc ttacgtatcc
     1501 tgtcaacgat aacttctatt tgatcaaaaa agtacgattc atttacgtct ccaataagtt
     1561 cggctaattc tttgaatgcc ttcgttacag gaagctgatt cttctgtaca aaaaagtaat
     1621 tagccaaagt aagcgggaag tgttctatag aggaaagtgt gataaaacgg tacttctcat
     1681 ttcctgcagt tgtcctcagc aattctgtct ctcggctgtt tcttactcca taaaaatacg
     1741 cttctttccg ttcatcttcg aaacaatacg cccaaataac ttctcccatc gctaattttt
     1801 gttcatcaac agagagtctc ttcaattgtt cagctatggt ttcagcagcc gaagtggctt
     1861 gttgcaagta atctttagga tcaaatattg gaaagttcaa atgatatctt cgttcttccc
     1921 tcttgattaa tcctgcatcg atcaataaat caagaaaatg ggaaaattta ttttgcgaaa
     1981 attctttttt caattctctt agaatcgttt cttgttctcg atgttcatat agataatcgg
     2041 tcaatgaaga aaaaagcgga tcatcggtca gtttttgata aaagttttcc ttattttttg
     2101 aataatagtt catatatgtt ctcttttcta tccgttttat tttacttaaa aggcttttac
     2161 gtaaaaagga ggaagaacaa gagtcataat tgactgttat tctcctccat ttcttcggcc
     2221 tttagtatgt tctatgtttc tttttatatc aatcgcttat ccattcattt tgaatgcttc
     2281 atactaccat ttgattagct aaatacagcc gtcaattgag gtacgacttg ttttttacgt
     2341 gaaacgacac ctttaagcaa agcacggttg ttggtcaaag ttgtttggaa agcttcttct
     2401 actttttctt ttcctttacc agcaacaagt aattctgaat cactgtctaa gatgtttgtg
     2461 acaactaata cgaacagatc gtagccattt gctttcattt catcttccat tgctgcttct
     2521 agctctgctt gtcgatccat cacttcatta aggtccactg tattgacttg agcgatacga
     2581 acgttggaac tgcccattgg gaaacttttt gcatccaaat caagaagaac cgcagctgat
     2641 ttatcactta gatttgttcc tgctttcaac atttcaagtc cataagtgtt tagatcgact
     2701 tcagcgattg ctgcaagttc ttttgcagct gcttcatctt caggcgtaca tgttggtgat
     2761 ttgaacaaca atgtatctga aatgatagct gagagcatga ttcctgcgat ttctttagga
     2821 attgttactt ggttttcttt atatagtttt aaaataatcg tacttgtaca tccaactggt
     2881 tctgcacgat agtacaatgg attagctgtt tcaaagtttg caatacgatg gtggtctact
     2941 acagctaaaa tatttacttc gctgatatct gaaatacttt gttggaattc attatgatcc
     3001 acaagcatga catctgcatt ttctgcttta gctgactcta ctactcgtgg tgcagatagc
     3061 tgaaagtggt ctaatgcgta ttgtgtttct tcattaggtg tacctagagc aactgcttct
     3121 gtttctttac ctaattcatt ttgcaagtgt gaaaacgcaa tggctgcccc gattgcatct
     3181 gtatctggat tttggtgacc aaaaactaaa atttttgaca tgtcattcgc tcctttgtga
     3241 tttctcctat ttaataatag caaaaaaacg gaaagaagca atacttatct tctttccgat
     3301 gcgacctatc gcgttaaata ttttgtatac tcttctgtat gaagcaatcg tttagcattt
     3361 tcgacacgtt cttttgtagg tggttcgatc ccttctaatg gatatttcaa accaagtgtt
     3421 tcccacttgt attttcccat cgtatgataa ggaagaatct ctactctgtc tacatttgac
     3481 aaggtttgaa taaagttgtc tagtcggatc aaatattcat cataatcact tcgctcagga
     3541 actagtacat ggcgaatcca aaccggtttg ttgatttttg acaaatattg agccatttct
     3601 aaaatatttt cattgtccca atgcgttagt tttttatgct cttcattatc gatgtgtttg
     3661 atgtcaaata acagtaaatc tgtatacttc atcaattctt gaaaacgtga aaagaaaggt
     3721 tcttcatacg taaaaggttt tccgcatgta tccaatgtag tatgcatctt ccgctctttt
     3781 gcttttttaa atagttcgat caaaaaatcg atctgcaata gaggttctcc accactaaca
     3841 gtaataccac ctttatctcc ccagtaaggt ctgaagcgtt ctgctttatc taaaagttca
     3901 tctgctgtgt attctttccc tccgccaata ttccaagtat ctggattgtg acaaaattgg
     3961 caacgcatgc ggcatccttg cataaacacg acaaagcgca gtccaggtcc gtctactgaa
     4021 ccgaaagttt cgatagaatg aacatagccg attgtttttt cttccattta agttcacatc
     4081 ttttctttga tttcatttta agtacaagtt agctgtcgaa gcgaagcttt ctgaacaaaa
     4141 tttttcgcaa ttgccgcttc gttatgtgta aaatttacag ggacggaaca tacaagtcct
     4201 gcccctgtaa atcgtttctt tcaaataagc atactgatta ttcgattttg atgcgatggc
     4261 tattcaacgt cctttcgacg ctaagtcgaa aaactttttt cacgaacttt ttacattctg
     4321 tcgtgtgaag ttctcatcaa gacatctaat tgttgttctc ttgtcaagtc acggaattta
     4381 actgcataac cagatacccg gatcgtcaag ttcggatatt tcattggatt ttccattgca
     4441 tcacgcaata aatcattact gaatacattg acattcaaat gataagctcc ttttgagaag
     4501 tatccatcta agacattacg caagttttcg attcttgtat cttgttcttt tccaagacct
     4561 gaaggattga ttgtttgggt atttgaaatt ccatccaatg cacagccgta attcatttta
     4621 gctgttgagt tcaggctagc taataaccca ctttgttccg cattgtaact tggatttgct
     4681 cctggcgcaa gtggttttcc agcttcacgg ccatcaggag tatttcctgt atttttaccg
     4741 taaacaacat ttgaagtaat cgtcaataat gaagttgttg gttttgagtt gcggtaagtt
     4801 ttatgacgtt tgatttgtcc catgaagtat tccaagatcc atgaaactaa ttcatctgca
     4861 cggtcatcat catttccgta tttagggaag tcgccatcca cttcaaaatc aactgctatt
     4921 cctttttcat tacggattgc ttttactttt gcatatttga tcgctgacaa gctgtctgcc
     4981 gcatgagaga tcccagcaat acctgtagca aatgtgcgtt gcaagtcaga atccatcaaa
     5041 gccagctgag ctgcttcata agaatattta tcatgcatat aatgaatgat gttcaacgta
     5101 ttgacatata gttctgctaa ccaatccatc atattcatga agttatgttt cacttcttca
     5161 aagtctagta tttctgatgt gattggacga tattctggtc caacttgggc gccagtcact
     5221 tcatcgactc cgccattgat ggcatataat agtgttttag ccaagttagc acgagcgcca
     5281 aagaattgca tgtcttttcc gacaactgtt cctgatacac agcaagcaat cgcacaatca
     5341 tcagaacccc attgttcacg aagctgatta tcattttcga attgaatcga agaactttcg
     5401 atagcgattc tgctagcata tgttctgaat ccttctggaa ggtgttcaga atacaaaaca
     5461 gtcaagtttg gttctggtga aggtcccata tttgttaatg tatgaagcag acggaaatca
     5521 ttctttgtaa ctaatgaacg accatctaat cccatacctg caatggataa agtagcccag
     5581 atagggaatc ctgagaataa ttggttatat tcaggtgtac gcgcgaattt gaccatacgt
     5641 aatttcatta ctaagtggtc gatcaattct tgtgcttctt tttctgtgat tactccatta
     5701 tccaaatcac gttggatata gatatcaagg aatgctgaga tacgtccgat tgacatcgca
     5761 gcaccatttt gtgatttgat tgctgctaaa tatccgaagt atagccattg gacagcttct
     5821 tttgcatttg cagctggttt agaaatatca tagccatatt tcgcagccat ttctttcatt
     5881 tgcgctaatg cacgatattg ttcagtgatt tcttcacgta aacgaatcac ttcttcactc
     5941 attgtatgat aaccagtcat atcatgatct tttttctttt gttccatcaa atagtcgatt
     6001 ccatacaatg ccacacgacg atagtcaccg atgatacgtc cgcgaccgta agcgtctgga
     6061 agccctgtaa tgattttgtt tttacgagca gcacgcattt cagcagtata agcgtcaaat
     6121 acaccttgat tatgtgtttt gcgccagtca gtgaaaatat gtgtcaattc atcgtttggt
     6181 gtatagccat tgctttttag cgcattgtta gccatattga ttccgccgaa cggcatgaat
     6241 gcttgtttca aaggtttgtc tgtctgtaga ccgacgattt tttccaaatc tttatccaaa
     6301 tagcctgcat cgtgtgaagt aatagttgat acgatttctg tgtccatatc atagacaccg
     6361 ttacgctcga attggatatc atttaacttt tgcaattcat cccataattt ttctgttgct
     6421 tctgttgggc cttccaaaaa gctgtcatca ccgcgatatt cagtgtagtt attttgaata
     6481 aagtctctag tgtctacgcc ttctttccat ttggtacctt taaatccatt ccattgctcc
     6541 attgtatgga cctcctaaat ttctgtttta tgtaacagtt tttacgtgat tagtataaca
     6601 cagcacccta tctttgcaag ggttttcttg ttttttattt aacaattttt atgttttatt
     6661 tacatatatt taaatcaacg ttgacatacc aacatttaag cattgtgaac actttcatct
     6721 ttttttgcaa acgtataagg atttattaaa aatgaatgaa aaagagacgc cacctgtatt
     6781 aatacagatg gcgtctcttc attaaaatac tacaacagtt acgactcgat gaaaatctca
     6841 ggagcatcga taacttcgat gacttctcca ccttttttct catccatcgc aaatgatcca
     6901 ttcgatgttc gatcacctat agggaaatca gttgggtcaa tcgttaactg ctgccctttt
     6961 tgattcatca aggttatttc ttttgatctt ccttccgaca tatagataat acggtgcgga
     7021 ttttttttca gctcacgcat gaccgtcact ccccgcttcg cacgtgaagt ttggctgatt
     7081 tcttgagcaa gcatgcgttt aacagctcct cgctgagtaa cgattacgat cggcgtatca
     7141 ccttctgcta acacaagcag cccgttgata atcctatctc catctttcaa attcatagac
     7201 ttcactccag ctgcctttgc tccaacaacg ggaacatctg ttaaaggata gcgcaaaccc
     7261 attccttgat gcgttactaa gaaaacatct aagcctggct gatcttcttt cagatacaca
     7321 gcaatcagtt catcttcttc cgcctttagc ttcatacagc tgagcggacg gctcttatag
     7381 gtgcgccatg gttcgaactc tgtcattcgt gtttgcttga tcaatccatt cttgctgatg
     7441 aatacaaatg ttttctctgc ttgaattttt tgatatggga aaacagctaa aatcgattcg
     7501 tctacagaca gattggagat tgtttgagaa atgtgctcac cagcatcttt ccatttcaaa
     7561 tcgggtagtt catggacagg gcggtagatc acatttgctt tatttgtgat cagaagaaca
     7621 tggtccaatg tactcaattc acctgagtat agcaagtagt cgccttctcg catcccgatt
     7681 tcttctggtt tggaagcact ataagaacga aggcttgttc gcttcacata gccttctcgc
     7741 gtcacactga caattacgtc ttcttgtgcc actaagactt gcgtatcaat tttgatttct
     7801 tcgatttcgt cttcgattgt cgttagacga gcggaagaat aatttttttt cacttctcgc
     7861 aattcttttt tcataacaga gaaaagctct ttgtcatttg aaaggatttt attcaactct
     7921 gtgatttgcg caatcaagct ttcggattcc ttttgaagct ctgtgatatc cgtgttcgtc
     7981 aaacggtata attgcaatgt gacaattgct tctgcttgtt cttctgtaaa ttgaaagacg
     8041 tcgactaaat tctttttggc gtcttttttg tctttacttt cacgaatcgt tgcgattact
     8101 tcatccagaa tcgataaagc tttcatcaat ccttctacga tatgctgtct tttttgagct
     8161 ttggctaaat cgaattgact acgttttgtt atgacttgct ttcgatgctc gatataactt
     8221 cttaaaatgt ctttcagtcc aacttgatgc ggagtcatat ggtcgatagc gaccatattg
     8281 aaattgtaat tgatctgtag ctcagtgttt ttgaacaaat aattcaaaat tccttgagca
     8341 ttggcgtctt ttttcaattc gacgacaatt tgcagacctg ttctatcact ttcatctcgt
     8401 acttcagcta ttccatcgat tttcttattc aaacggatct catccatttt tttcaccaag
     8461 gtcgctttat ttacttcata tgggatttct gtgatcacga tttgctgttt attacccttc
     8521 attgcctcta tctttgtttt cgaacgaaga ataacttttc ctcgtcctgt ttcataagct
     8581 tttttgattt catcttttcc ttgcaagatc cctcctgttg gaaagtcagg tccaggaata
     8641 tattccatca atttttcaag gctcgcttgt ggatgatcga tcatatagat tgtgccatcg
     8701 atcacttcag ctaagttatg agtcgggatt tctgttgcat atccagcaga tatacctgtc
     8761 gatccattga cgagaaggtt tgggtatcga gctggaagga ctgttggttc tttttctgta
     8821 tcatcaaaat tccacacgag atcgactgtt tctttctcga tatctgctag catctctcca
     8881 cttaacttgg ataatctggc ttcagtataa cgcatcgcag caggtggatc accgtccata
     8941 ctcccgttat tcccgtgcat ttcgatcagt acttcccgca acttccagtc ttggctcatg
     9001 cggaccatcg cttcataaat actgatgtca ccatgaggat gataattccc catgatattt
     9061 ccgacagatt ttgctgattt acggaatcct ttgtcatacg tattgccatc tttgttcatg
     9121 gcaaataata tccggcgttg cactggcttc aatccatcac ggatatcagg cagtgcacgt
     9181 tcttggataa tatatttgga ataacgtccg aagcggtcac ccatcacttc ttctaaagtt
     9241 aattcttgta cttcttgtcg attttccatc aggtgacctc ctattctact tcaaataact
     9301 gattgttttc atttttatct gctcgttctt catctaataa atcattagaa actgaaggag
     9361 agatttcagt atcctctttt ttatctaaga tactgccatc ttcttcgagc gtaaattgca
     9421 cgtgattttc gatccatttt cttcgaggtt ctactttgtc acccatcagt gtggttactc
     9481 gacgttcagc ttgcgcagca tcatcgatac ggacgcggat caacgtacgg gaagtcggat
     9541 ccatcgttgt ttcccacaat tgttccgcat tcatctctcc aagtccttta tatcgctgca
     9601 gcatatatcc tttgccgact tttttaatca ttgctgccaa ttcgtcatct gtccacgcat
     9661 attcaatgac ttgcttcttt ccttgtcctt tggatacttt atataaaggc ggtaacgcga
     9721 tatatacttt cccagcttca atcagcggtt tcatataacg ataaaagaaa gtaagcagta
     9781 atacttgaat atgggcgccg tctgtatccg catcggtcat gatgattact ttgtcgtaat
     9841 tacagtcttc gatagaaaac tcaggaccga ctcctgcacc aatcgtatag atcatcgtat
     9901 tgatttcttc atttttcaag atatcttgca ttttagcttt ttcggtattg atgacttttc
     9961 ctcgtaaagg tagaattgct tggaactttc tgtctcttcc ttgtttagca gatccgccag
    10021 cagaatcccc ttcgactaaa tacaattcat ttttcttagg gtttcgggat tgtgcgggtg
    10081 tcaattttcc tgaaagaaga gattcgcctt ttttacgctt cttcccattt cggctttctt
    10141 ctctggcttt acgtgctgct tctctcgctt ctctggcttt gattgcttta cggaccaaca
    10201 tctggctcat ttcgctattt tcctgcaaat aaaagcccat ttgttcactg atgacgttat
    10261 ctactacggt acgagcaact ggcgtaccaa gtttttcttt tgtttgccct tcaaattgca
    10321 gaagattttc aggtacacgg atagaaagta cagcagctaa cccttctctg aaatcactac
    10381 cttccagatt cttgtcccgt tctttcagca aaccaacttt tctcgcatat tcattataag
    10441 atttcgtcat cgccgctttc ataccagctt catgggttcc cccatctttt gtccgaacgt
    10501 tattgacaaa agataaaaca ttttctgaat aaccgtcatt gtattgataa gcgacctcta
    10561 cttcgatacc ttctttttct cctgaaaaat aaacaactgg tgtcaatgta tctttttctt
    10621 cattcagata atcaacaaat tctttgattc cttcttcgta atgaaaaatt tccttgactg
    10681 gttcttctcc acgaagatca gaaagagaga ttttaacgcc ttttagaaga aaggcagatt
    10741 ctcttaaccg ttcggctaaa atttcatatg aaaatttcgt tgtactgaat attgtatcat
    10801 ctggtaaaaa atggacagtc gtcccgtttg ctttttttgt ttttcctatc tttttcaaag
    10861 taccgtcagg tttaccgccg tttttaaatt tctgctgata ctctacgcca tctctaacga
    10921 tcgttacaat tagccatttc gataaggcat ttaccacact ggctcctaca ccgtgcagtc
    10981 caccagaagt tttgtaccct ccttgaccaa actttccgcc agcatgcagc acagtaaaaa
    11041 tcacttcaac tgttggtatt ccggaagcat gcattcctac aggcatccca cgtccgctat
    11101 ctgcaacagt tatactattg tcttcatgga tggtcacatc aatctcactg ccataacctg
    11161 ataatgcttc gtcaactgca ttatcgacga tttcatagac taaatgatgc aagcctcggc
    11221 tgtcagtgga tccaatgtac atccctggtc tttttctaac tgcctctaat ccttccaata
    11281 cttggatgga cgagtcattg tattcgttgt ttactttttt tgccaaggca aacgctcctt
    11341 caataatact ttgcggcaaa accgcaccac gattatcata ctagaaaagg tcgtgaaaaa
    11401 aaagagggta gacgagaaat caattttaat tatctcctaa ccgctttttc gacattcccc
    11461 tctatcgatc atctcttctt tgtggtcatt tttatttttg gttttctttc aacttaccaa
    11521 gttcaatctt aatacaacga tccattacga tatctgtacg tcctgctttt cttagcatct
    11581 cagctgcttc tttgttttca atccctaatt gtgcccagaa cactttagca tcagttttca
    11641 aaaaatcacc tgctatttca ggtaaaaatt cactccgtct aaatacatct acgatatcga
    11701 ttggatcatc gatttctgtc aaattcgcat agactttctc gcctagaatt tcttcaccag
    11761 ccaataatgg atttactggt atgattttat atccattgtc ttgcaatacc tgtgcaacca
    11821 tgtaacttgt tcgttctggt ttattgctca agcctacgac ggcaatattt tttgcttctt
    11881 ccaaatagtt gaaaatcgtt tcttgtgttg gattttttac agacatttct gccacccctt
    11941 gcttttcttt ttattccatc tattatactt gcatctttca ttttttcaat tgttcctgtt
    12001 acctattcat gctaaaataa aggatagttt tcaacttgaa agagggtaaa aaatgaaatt
    12061 gatcttatta cttattttag catatctttt aggttctatt ccttccggtg tctggattgg
    12121 caaattgttt ttcaaaaaag atatccgaca acacgggagc ggtaatactg gaacgaccaa
    12181 tacatttcgt gtattaggca aaacagccgg gattgttgtc ctgcttatgg atattttaaa
    12241 aggtacattg gctacttgtt tgccgatgat cttccacctt tctgggatta accctctttg
    12301 gtttggggta tgcgccattc ttggccatac atttccgatt tttgctgggt tcaaaggagg
    12361 aaaagctgtt gcgacaagtg caggaatgct tttaggactt aatcctgtat tttttgttta
    12421 ttcttgtatc atctttatcg ttagtttatt ttgtacaagt atggtgagtt tgagcagtat
    12481 gatcagtgca gtattgatca ctttatctac gatcgtcctt ccttatgtag ctcctgtgat
    12541 tttggctaag cccaattggt tactgacgat cattgccttt ttagtttctt cctttatctt
    12601 ttatcggcat aaagacaata tcaagcgtat cagaaaccat actgaaagtc gaatcccgtt
    12661 tggtttgaat agcagcaaga aaaaatcctg atactttttc attccaaaga gataaaacgg
    12721 gagtgtgaca aatcgatgtc acactccctt attacttaca ggatagcttt tttacacacc
    12781 ttggtaaacg gtgttccctg ctaacttctc ggtcacaacc tcttacttca ctgtgatgga
    12841 atattttgtc ttgaagattt catgggcacc tagttgattg atccctactt tttccatcaa
    12901 gtttccacta ctgttcaccg tgtcagcgat tccgcaccac ggttcgatac aaacgaaagg
    12961 cgcttctttt ggataaggag accagatccc tacataaggc atatctttat agcttaaagt
    13021 tacgctatgg gaagattttt cacttcgaat ggcgtacgca tttagacccc ttgtttcaaa
    13081 aaccaaggca tcttgctcaa aaagttcacg attcaaagcc agattcgtat ttgtctgacc
    13141 taacgtcttt tgatccatat cgatgaatgg gcctttcaat ggtaggcgta atcttgattt
    13201 caatggagaa aatgccagat agaaatcttc aaatgacaat ccttcttcaa gaggtacatt
    13261 gaaagcagga tgtccaccga tagaaaagaa catttctttt tcaccggtat ttgccacttg
    13321 ataatgaacc gtgatgccgt ctcctcctaa ttcatagctg atcactaatt caaaatcaaa
    13381 tggatacttt tctaatgtct ccggcgtact ccttaagatg aaactagcca tttcttgtcc
    13441 atgttcaatg acttcaaaat ccatatcccg agcaaatccg tgttgcccca tttgatatgt
    13501 tttcccttga taaacatact gatcatcttt taaacgtcca acaaaaggga ataaaaccgg
    13561 tgcatgtctg ccccaatacg ctggatcacc ttgccagata tactctaaac catgttcttt
    13621 tgatttcaga ctgatcaatt ccgcaccgtg ttcagcgatt tcggcgatca gctggtcatt
    13681 ttgaataata acagtcattg ccattcctcc aacttcgact tactttttaa aatgggaagg
    13741 ctggaacaaa catttctatc tgccccagtc cccttacttc taataactgt gttttgctaa
    13801 ctcgtcttta aaacgggaat tcaatacttt taaataagtt cccttcatgc ctaacgaacg
    13861 agattcaatg attccagctg attccaattt tcgtaaagca ttgacgatca cagaacgagt
    13921 gatgccgata ctatcggcaa tattagaagc agtcagacga ccttcatctc catccaatgc
    13981 ttcaaagata gcttgtacag ccttcaattc gctataagat aatgtgttga ttgccatttg
    14041 gacagccgtt gcactccgta catctgcttc gatgcttcga gacttctgat aaaggatctg
    14101 cataccgaca accgtagctc catattctgc taagactaga tcgtcatctg caaacgattg
    14161 ttccatacga gataagataa tcgtacccaa acgttcgcca gctccaaaga tcggaacgac
    14221 agtcgtcaga ccaaatggat atttctctct tgactctacc ggaaatgcag taatatcact
    14281 agtaattggg atattagctt cagttttcat caactgtgcc actgtatcag tataagattc
    14341 aggaaattgt ttctcaacaa acattgtttt gattcgttca ttgttcacat cgtgacgttc
    14401 attataacct agtaatactc cgtcacttcc tatgatatag gtgttgctgt caagaatacc
    14461 acctagtgtg acagccattt tatcgtaagg caaatctgct tgcatgtcaa aagtattctt
    14521 ttgctgcaaa agtgtgttta tcttgcgggt tttcgttagc aagtctgtca ttgtcgtcct
    14581 ccgatttttt ataaaatata gcgacttaaa tcttcatttg ccgcaattga gccaagtttg
    14641 tcatccacat atgcttctgt gatcgttatt tctcccattt gcatatctgg tgcttcaaat
    14701 aatagatctt ctagtagttt ttccaaaatg gtatgcagtc tgcgtgcgcc gatattatct
    14761 gtgtcacggt tgacatcgaa agcgatttga gcgatccgtt caattgcttc ttttgtaaac
    14821 gtaactgaca cattttctgt accgatcaac gcgacgtatt gttttactaa agcattattt
    14881 ggttcggtca gaatcttcac aaaatcttca gctgtcaaat catctaattc tacccgtatc
    14941 gggaagcgtc cttgaagttc tggaattaga tcacttggtt tagacaaatg gaaagctcct
    15001 gaagcaatga ataggacgtg atctgtttgg atgatcccgt attttgtgtt tacttgtgaa
    15061 ccttcgacaa ttggcaatat gtctctttgg acgccttctc tggatacttc tccagattgc
    15121 tgtgatttag aagtgatctt atcgatttca tcgataaaaa taattccact ttcttccgct
    15181 aatttgattg cctcactatg gatatcagca tccttgacta attttgctga ttcttccttg
    15241 atcaataact ctaaagcttc tttgactgtt accgtccgtt ccactttttt cttcggtgtc
    15301 aaagcaccta gagtttcatt taggtcgatc cccatttgct ccaatccatt gttcatcatt
    15361 ggtgcaggtt tcttttggtc ttcaacttca atggttactt cacgactatc cagtaaaccc
    15421 ttttgtagtt gttccaagac tgtacggcga ttgattcgaa tatcttctgt cacttcttct
    15481 tgcggttcag cggtattttg ctgactagca ttaaaaagat tcatcatttg ttcaaattga
    15541 ttagtggatt gtttctgttc ttttttgata ccaggtacca agatttttac caaacgtttt
    15601 tctgcatttt ttttagcact tgtgtataca cggctgtact gctctttttc tacgatttgg
    15661 atcgcatttt ctactaaatc ccgaaccatt gattctacat ctcttccgac ataaccgact
    15721 tcagtaaatt ttgttgcttc gactttgaca aatggtgcat tgacgatttt tgccaaacgt
    15781 cgtgcgattt ctgttttacc gacccctgta ggtccgatca tcagcatatt ttttggtgta
    15841 atatcttgtt gcattttttc atctaactgc aaacggcgat agcggttacg caaagcaacg
    15901 gcaacagatt tttttgctgc gtgctgtcct acgatatatt catctaattc acttacgatt
    15961 tgtcttggtg tttgttttaa ttcatacata tctactcacc tcttacagtt cttctacgat
    16021 aatattatga ttagtaaaga tacagatatc tgcggcaata tttaacgcat tttctgcaat
    16081 ttctttcgca ctcatgtcgt tttgagcata gtttttcatt gctcgggctg cagccaacgc
    16141 aaaattccct cctgatccga tagctaagat accatcatct ggtgtgataa cttctcctgt
    16201 acctgaaaca agaagcattt ctttatcatt cattacgatc agcatcgctt caagtttttg
    16261 catagattgc tgtgtccgcc attcttgagc taattcgaca gctgcgcgtt gtagattccc
    16321 gttatattcg tttagtttgc cttcaaattt ttcttctaaa gtaaacgcat ctgcaacact
    16381 tccggcgaaa cctacaacaa cttctccatt gtagatacgt cgtactttct ttgcagtgcc
    16441 tttcatgaca acagattcac ccattgttac ttggccatct ccagccatag caaatttccc
    16501 gtctttttcg acggcacaga tagtggttga atgaaatggt gattcgacca tgtttgtttc
    16561 ctcctaaatt tgttcttttc cttattttta cgctcttgga tggaaagaac gatagttttt
    16621 ttgtaaactt tcttttgtta catgggcata gatctgggta gtcgataaat tggcatgtcc
    16681 tagcaattct tggactgtcc gcaaatctgc cccattattt aataaatgag tagcaaatgt
    16741 atggcgcagc atgtgaggat ggatatcact atccaaactg ctttttttga tcatttgatt
    16801 caagacatat tcaattccag taggcgtgat tggttttcca tgatgattca caaaaacgat
    16861 atcatgctct tcgtgatatt ttgtcatcaa tacctggcgg ccttccctga aatattcttg
    16921 cagagcatct tgagcaaaag aacctagagg agcatatctc tctttgttcc ctttaccatg
    16981 gatcaacatg acctctgaat caaaatcaat gtctgatacc gacaaactgc tacactcact
    17041 taaacggatg cctgacccgt aaaggacttc cagtaaagcg cggttcctca aatccaaagg
    17101 actatctcct gctacgctgt caaaaagtgc ttgcatttca ttttcataaa aaaaacgtgg
    17161 cagtctcaaa tttttctttt tgagatgaac gtaagaaaat ggattttctt ttatcacttc
    17221 ttctttgaga agatactgat aaaacgaacg taggctggct atcttgcgac tgatagaatt
    17281 tctgctatag ctaggacgat gatcagctaa tgcactcaaa tagacacgaa ccgtaaaata
    17341 ttccgccttc agcagatcag cgtctccaga ttcctccaaa aaatgtttga aatggagaat
    17401 gtcttcttca tatgcttctt tcgttttttc tgaatatcct ctttcgacaa tcaaataacg
    17461 caaaaatttt tgttcccacg tggcttctgt cattttctca ccttcctttt gtcccagaga
    17521 ataatttagc acagcgttta taaaaagaca aataaattgt cagaatttaa ccaatatttc
    17581 taagtttgtt cacaattggc gcaattcctc acattttgtt tgagaaattc ttaagaaaaa
    17641 cgcaagaaaa agagcgagac tatccgtctc accctcttca tggagtttcc ttactcattt
    17701 gggattgcag ttttttctaa ttctgttttt attgcctcat tagcttttaa agctcgttgt
    17761 gcaattgctt catatcttgc ttttttgtct cgaatgcgct ctggcagttc aggaaacaga
    17821 ccatagttgg cattcatcgg ttggaaatgt tttccttccg catgagtaat gtagtaagcc
    17881 atacttccaa tagctgtttc ttgtggaaac tcgactggtt ccatttcttt tgctaagcgt
    17941 gcggcgttga ttccagcaag tagtccgctc gctgcacttt caacatagcc ttctacacca
    18001 gtcatctgac ctgcaaagaa cagatcttcg cgtttcgttg attggtaagt cggtttcagc
    18061 aattctggcg aattcataaa gctgtttcgg tgcatcacac catagcgaac gaattcagca
    18121 ttttctaacc caggaatcat ccggaaaaca cgtttttgct cgccccattt caagtgagtc
    18181 tgaaagccca cgatgttgta taaagaagct gcagcattgt cttgacgcag ctggataaca
    18241 gcataaggac gtttgccagt tttaggatct tccaatccaa ctggtttcat aggtccgaaa
    18301 agcatcgttt tgaatcctcg ctgtgccatt acttcaattg gcatacatcc ttcaaaatat
    18361 ttttctttct caaaagattt aagttctgcc acttcggcat tgattagtgc ctcatggaaa
    18421 gctttgaatt cctcttctgt catcggacag ttcaagtaag ctgcttctcc tttgtcatag
    18481 cgggacttca aatatacttt atccatatcg atcgtagctt tgtctacgat tggtgcagct
    18541 gcatcataga aataaaaacc atctgaacca ttgaatgctt tgatgctttc tgctaatgga
    18601 tgagaagtca aaggtcctgt tgctactacg gtgattcctt ccggtatttc agtaatttct
    18661 tcgtttatca ctgttactaa tggatgctct ttgacttttc gggtaattgt ttcagaaaaa
    18721 gaatcgcggt caacagctaa ggcaccacca gctggcactg ctgtttcatc tgccgaagtg
    18781 attactaccg aattcaatcg gcgcatttct tctttcaata accctactgc attagccaaa
    18841 ctgtttcctc ttaatgaatt ggaacatact agttcagcaa aattacttgt gtgatgcgcc
    18901 tcagtcgatt tgactggacg catttcatat aaacggacag ggactcctgc ttgtgcgatc
    18961 tgccaagcag cttcacttcc ggcaagccct gctccaacaa catttaccat tttcaatgaa
    19021 agaacctctt ttctattatt tttggatgtc ttcttcgtaa tctccattta cacagactac
    19081 ttgtttaccg cctttgactt tcttctcgac cagatatccg tcacattttg gacaatttct
    19141 gcccactggt ttatcccaag aagtgaattc acattctggg aaacgggaac aaccatagaa
    19201 tagtctgttt ttcttagatt ttcgttcaat gacttgtcct tcatgacata ctgggcaagt
    19261 cacaccgatt tcttttacga ttggtttcgt attccgacaa tcaggaaaat tactgcaagc
    19321 ataaaacttc ccatatttcc ctaattttat caccatcgga tgtccacaga catcacaatc
    19381 gaatcctgct ggttcatctt tgatttgaat tttttcgatt ttttcttccg cattcgtcag
    19441 ttctttttca aacggtttat agaaacgatc aaccactttg acccacgctt ccgtgccttc
    19501 ttcaatttta tccaaatctc cttccatttc tgctgtgaaa tggatatcga cgatttgagg
    19561 gaagaattca cagattaatg aattgacaat ttctcctagt tcagtcggct caaatctttt
    19621 ttgtgtcaat tttacatagt agcgtctttg gatcgtatca agtgttggtg cataagtgga
    19681 aggtcgccct accccgtttt cttctagtgc acgaatcaac gtagcctcac taaaacgtgc
    19741 tggtggttga gtaaaatgtt gttttggttc aatatcaaca gattggacta catcgccttc
    19801 ttcaagttct ggaagaatat tttctttctc ttctttgccg tcatctctac cttccacata
    19861 cacttgcatg aatcctttga atttgatttt tgaaccgttc gcaatgaaga tgacaccatt
    19921 ttgttctaat gtcactttca ttgtatctaa aatagctggt gtcatctgac tagccacaaa
    19981 acgtgaccag atcaatgtat aaagtttcaa ttgatcttta tctaaatatt gtttgagttc
    20041 atctggtgta cgaagcacac tcgttggacg cacagcttca tgggcatctt gtgcgccttg
    20101 agcatttttg atctttcggt gatcatgtct agaaaattct tttccatacg tatcttcaat
    20161 aaatgctgcg gcctctgctt ttgctgtatc ggcaatccgg gtagaatcag tacgcatgta
    20221 tgtaatcaag ccgactgttc cttgtttacc caaagtgatt ccttcatata attgctgtgc
    20281 taccatcatg gtttttcttg ttcgaaagtt taacttacgg gcagcttctt gttgcaggct
    20341 acttgtagtg aaaggattcg cagggtttct tttgcgctct ttcttttcta cttttttaac
    20401 ttcgaagtct gttccatcaa ttctagcagt gacttctttt acactttgtg catctggtaa
    20461 tttctttttc ttaccgtcga ttccccagaa atttgctttg aatttcttgc gagctttttt
    20521 aaaattaccg tcgatgctcc aatattcttc tggaacaaat tctcggatct ctttttcacg
    20581 gtcaataata atttttaaag cgacagattg gacacgtcct gcacttaacc ctttcttgac
    20641 cttacgccag agaataggac tgatcgaata accaacgatt ctgtctaagg tacgacgagc
    20701 ttgctgtgca tctactaaat ctacatcgat cgttcttggt tccttaaaag ctgctttgac
    20761 tgcgtctttt gtgatttcat tgaagaccac ccgatttttt tctttcagat ccaacccaag
    20821 taggtacgct aaatgccaag caatcgcttc tccttctcta tccgggtcac ttgccaagta
    20881 aactttttga gctttttttg ctgcggcttt caggcttttg atgacatcgc cttttccgcg
    20941 tatagaaata taatggggtt cataattgtt ttcaaaatcg atacccattt tacttttcgg
    21001 taaatctctt atatggccaa cactggccat tactttatag tttcgtccaa gatatttctc
    21061 aattgtcttg gcttttgcag gtgattctac aatcactaaa tatttatacg ccattactga
    21121 atggactcct ttccattgtc gtgttcctac tattaaaaga ggattcatac aaatcgtagc
    21181 taatcatatc cattcagaaa acgtttgtca agaaaagcaa atgaaaagta tggtgttatt
    21241 ctttaaattc tgccaagata tcttcacccg aaaccgtgca aactgcaccg tcttggatca
    21301 aatgatgaca tccggtagaa tgttctgtta aaatatttcc tggaacagaa aaaactgttc
    21361 ttccaagatc caatgcttgc tgtgctgtta tcagagagcc gctttttttc ttggcttcaa
    21421 agacacatgt tcctttagac aaagctgcga taatccgatt tctcattgga aaacaatgct
    21481 ttttcgggcc ggattgagga ggatattcac tcaaaagaag atgatcattt gcaatcacct
    21541 cttgcaagtc acgattttca gcaggataga cttgctctat ccctgttcca atgactgcga
    21601 ttgtccgtcc accatgagag attgctgctt ggtgaccgta tgtatctatc cctttcgcgc
    21661 agccactgac gatcacatat ccagcttcta tcactggttt tagtaaataa taaactgttt
    21721 ttttggctaa agcagaagtg tgtcttccac caacaacgct taacatgtta caagaaagta
    21781 aagatagatc accattataa aacagtacaa ttggcggata ggtcaagtga agcagctgag
    21841 ggggatattt gggatcaaag caagtgataa acgactgttt cgattggatt ttgccccagt
    21901 tagcgtgaat ttcctgccaa cttttgcgaa acagctcccg gtgtttggtt attttaccta
    21961 tcttaatgat gtcttcaaat ccgatttctt tataaggata ctgcatcatc cagttagcaa
    22021 gtgcccattt tccttgacta ctgattcctt ttgtataagc aagtttcaat aaattttctt
    22081 ctatttgata catcataaaa ccgcctttcg tctctctttc taataagata cgtaaaagcg
    22141 gctgtttttt attgtaaata tttttttaca ggtgcaaaac ttttacgatg gattggcgta
    22201 attccttgtc gttcaagtcc ttctaagtgt tcctttgttc cataacctgc attatgcgag
    22261 aaaccatatc caggataaag cacgtcatat tctttcatca attggtctcg atatacttta
    22321 gcaatgatac ttgcagcagc aatcgacaca gatcgtgcat cccctttgat tattttttcc
    22381 tgctgaatag gcaaatccaa ggtcatcgca tcgatcaaca aatagcttgg tacaatggac
    22441 aatttttcta ctgcttggat catcgctaat ttacttgctt cataaatatt cacatcatcg
    22501 attgtctgct gatcaacgat cccgatcccg attgccaggg ctttttcttg aacttgttga
    22561 taaagaagtt ctcgcttttt ctctgataat tgtttggagt cattcagccc taatatgatc
    22621 tcatttttcg gcaagataac tgcagctgcc acgacaggtc cagctaatgg tcctcttcct
    22681 acttcatcaa tgccggcaat ccattggtga ccttgtgcgt acccttgctt ttcaaagcaa
    22741 aacatttctt catatttttc cttaattaat gcttcctttt tcaatcgtcg ttcaaaagaa
    22801 gccagtgctt gctgcacgcc tttgcgtgga tcatttctta atgattctag tgtaggatca
    22861 tctattctct gtatgctttt caatcgttct ttgatacttt ggatggattc agtcatcact
    22921 tttttgctcc atttcttcgc aacgatccag tgtgtatcgt ccaagttttc cttgacgaat
    22981 atcatgcacg actaattcgc tgccacgatc atagtcttct ttatacccac gttttgctgt
    23041 aatatccatc agtaattccg gtgccaattt ttcttcttgc tcgattgata aaccataacg
    23101 atcgctgatt cttcctgaat aatatcgggc aaaaaagtct aatccgtaaa tcgctaaatc
    23161 atctaaatgg acaagctggt ctttgatcgc gcctgtcagc gctagttttt tgccgatttc
    23221 ttcatcttca aatttgggcc ataaaatccc tggtgtgtct aacaattcca actcattacc
    23281 taaacgaagc cactgctgac cttttgttac gccaggctta tttcctgtct gtgcaatttt
    23341 cttgcctact agtcgattca tcaacgtaga tttcccaaca tttggaatac ctaagaccat
    23401 tgcccgaata gcgcgaggct tgatcccccg agcagcatct cttgcccgtt tttctttcaa
    23461 tgcttcttta gccgcaggta ctagaccttt aattccttta ctttcttgtg ccgtgatagc
    23521 taatgcaaga tggccttgtt tacgaaaata ttcttgccac agctttgtct gttgtggatc
    23581 tgccagatcc gctttattca ataaaacaag gcgaggtttt tgctgaatga tctgatctag
    23641 cattggatta cgagaagata aaggtaatcg tgcgtctacc aattcaaata cgatgtccac
    23701 atatttcatt ttttcagaaa cttctcgtcg ggcttttgcc atatgtcccg gaaaccattg
    23761 gatggtcatt gttctctcca ttcctttcat accggaatat tccccggctt tacttgtttt
    23821 tttctttttc aatataaatt cactttttta ttataaagaa attccatcta ttagttaagt
    23881 gaaagtgaac cagtcctcat tctatcacat cttcactttt ttgatgatgc aaatttttat
    23941 tttggtttct atatatgaat ctaaattttt gacagcgttt cctaaataag agatgataga
    24001 cgaacaaaac agaaaggaga cgaaacaaat gaatagtatg gtttttgtta attttcctgt
    24061 tgctgatgtc aatcgttccg ttgcttttta tgaaaagctg ggttttaaaa aaaatgaaga
    24121 attttctact gaagaagctg gttcaatggt atgggatgac actttttgga taatgcttct
    24181 ctctcatgat ttttataaaa aatttataaa agataaagaa atagctgata ataaaaaaac
    24241 aagtggtgct ttgatttcgt ttagtgttga aaatgcggat gaagtaaaaa aatttgctca
    24301 aattgcaaaa gaaaatggtg gtactttcca cgaagtagat atgggaatgc ctgaagaaga
    24361 aatgttttca ttagaagtcc aagatctaga cggaaataca ttagaacccg tatggatgaa
    24421 gatgtaagca gataactaat ctgacgtttt ttataacaaa aaaacaaagg cggatgatac
    24481 gataagtatt ctccgcctct atttttttta ttcgtacaat ctctttttta cagtttataa
    24541 aagcagtctt ctcacccttt ttttaattgt tagatgccag tgtatgtaaa tcaccaatgt
    24601 gtcatgacac attggtgatt ttatggtatc cttttattat taactgacaa aggagagaat
    24661 attttgaaca ctttgattgc aaaagacgtt tttagattgc ccgaaatgaa tgcaagattg
    24721 ttgtcgacct ctgctctttt attagccctt gatgtcatct tatacaagat agcgattggt
    24781 cctgcttatt ttcaaatcac attcggattt ttaagtatgg cgcttatggg ttatctatat
    24841 ggaccgatct gggctggttt gcttgaaatg ttgtcgaaca ctttaaattt cacgatattt
    24901 ggttcaggaa cgtttcaagc tgcttttctt atcacggctt tccttggtgg atttattaat
    24961 ggcttatttt tatatcataa aaagataaac ctgccttccg tcatcgctgc ccaattattg
    25021 attatgatcc cagtcagcct ttttatcaat tcttggctga tgtctgtttt gtttggtgca
    25081 gatttcaaag taatttttct aggtagattc atcaggaata tgatccaaat ccctattcaa
    25141 ataatggttg tttattcatt tatcaaaact ttagaggcta gaaaagtgtt taaacgagct
    25201 gtttgatttt acgtactaag gtagtaaact gattttggat taaacaataa agcgtgcagt
    25261 ctcaacagac tgcacgcttt attgtttctc actggatcca ttttatttca tcaagtggat
    25321 aatagacaaa tcttgcttta cctagaatat cagttttatt gatcgtgcca aacgaacgac
    25381 tatcttttga aactcttcga ttatctccaa gtacaaaata attatcttcc ggaagcttgg
    25441 attgtcccgt tagctcttgt agtgtaaagt ccgtcgtata ggatgcattt gcatgatctg
    25501 atttcaggtt tttagttaga taaggttcct taactacttt cccattgatc ttcaattgat
    25561 cattttggta gctgacattt tctcctggaa gaccgattac tcgtttgata taaatcgtgc
    25621 catctgctaa ttgaaaaaca acaatatcaa atcgtctgat ctccgaaaat ttttccatca
    25681 caaccatatc accttgcttc aacacgtttt ccattgaatt gccttccact ggtaccggga
    25741 tgaataaaaa tccccgcaac atgaacgcaa ggaatacaga aacaagtaag tatttgaata
    25801 caagccagaa gcgattaata tagcgttgtt tttttgtcaa tctctatcaa tccatccctc
    25861 tttttttcat tctttcttta ttataagaaa aatatcaaaa aaatgcgact agatagctga
    25921 aataaaaata attctttcaa ttaggctatt ggacaaaaaa cttttttgat cataaagtac
    25981 aaaactatct cttatatgtc atgattattt tctaaatatt tttcccatgc ttcgtcaaag
    26041 atatccatgg acggcaaata gtcgacattc agttccagat aattagaaat ttcttcgtag
    26101 ctagagctgt gcttaggaaa ttggatgtct ttaccggctt ctgtagcgaa aacagataaa
    26161 gcatcatgtg tgccaccgcc tcgcagtgtc attaaataat gaaaaaagct tcgattcacc
    26221 cttcgttcct ccaattttct tcgataaagg cagcccggcg tgcatggttt cttttaaaat
    26281 tttcaggatg ctttttataa tactcttgat ggtcttcttc tgctagataa aatggttggg
    26341 ctggttcgat ttttgtaacg attggctgtt cgaaacgtcc actttcagct aactgtttct
    26401 tacttttttc agcaatgatc cgctgttctt ctgtcaaata aaagatcacc gggcgataat
    26461 tgtcaccgcg atcctcgaat tgtccgaaag cgtcagttgg atcagtttgc tgccagtaaa
    26521 gttctactaa ttgttcatat gaaatcaatg ttggatcata gataatctcc actgcttctg
    26581 tatgtccagt cgtttggctt tttacttgtt cataagtcgg atctggtaca tgccctccag
    26641 tatatcctga catcactgta tggataccag gaagcgtgtc gaaaggctgg atcatacacc
    26701 agaagcagcc tcctgcaaat attgctcgtt ccattatgat tccccctcta atactactca
    26761 tccgatgatt ttttattttc ttttgtcttg ctttcagtac tgctggtgct agttttgttg
    26821 gtatttgagt tgtttgaagc atcagaggta tcttttggca aatatagact aaaccgaatg
    26881 tcatcattta ctaagtcgat tttatctgct ttaatataca tcccgttttg cattcggaat
    26941 tgatccaacc taagcatgat agtcagatca tctgtattga cttcgatcca atctggtaat
    27001 ttatagtttc tcttgatcat attcatcaca tctttgattg gcaaactcaa tgttccgata
    27061 gaaagacttc tagcttttag ttggacattt ccgttttcca tcacatacgg atcaaaatat
    27121 aaatagaaat cgataggaaa acctagtact tcgaaagtac cattgagtag tgcttcattt
    27181 tccaaataaa atttatattc aatatcacta tctttttgat actcactaag gaaaaagctg
    27241 atgatttgat tgactttttc tttatttgaa ttgatcgtta agacaggatc tccttgtctt
    27301 tccgtaagag ctggtatttc tgggagttct ggttcccgat tagcaaaaat acggctgcct
    27361 aaaaatacgg tcgaaccaag tactacccca agaaggataa ggaaggcgaa tttccagtaa
    27421 tttgttttct ttgttttgtt tgaagatacg tcagatcttg ttttcatgtt tattgatcat
    27481 cctccttctc taaccattgg ttttgtgtct cgatcagctg atctctcact gcatttgcca
    27541 tcaattgata acctaaatta tttggatgga aatgatcttc ttcatagagc acattatttt
    27601 tgatgccatt tagattttct gtcgtgctag ttgtttgatc tgttccttct tctgtgacac
    27661 ctacttcctg attcaatcct tgataaagca aatcattgat tgggataaag tagcagttcg
    27721 gcattttttt tgtcaccgtt tctgttcctt tgttccaatt gttaacaatt gtctgcatgt
    27781 cagtgatctc aggaaagttc aaataaaatg gattgtagat gcctaaaatg taaataggtg
    27841 cggttttatt gagggatcga aattcttcca atagttctgt gacattttcc tgatagtttt
    27901 tcagtggctt tttaaaggaa ttgaccgtta acccgaataa attattttgg ataactttca
    27961 tcaaatcatt accgccaaca gtcagtgtga taaaatcagc tgttttgata ttgtttcgaa
    28021 tttcttcttt tgtttttact cgctttaaga tctggtcact tcgttcacca tttacaccat
    28081 agttttctgt ttcaaccgcg gtcaaattat aacggtcttt tagatcattt gcgacaaggg
    28141 gaacgaatcc tccttgcttg gtttgatctc ctactccttc agtcagcgaa tctccgatag
    28201 ctatgtagtg aagtttttct tttttatttg gatcttctct cacagtagtt actggtttca
    28261 ttagtgggcc agctttcggt atagaagcag ctaaacctgc atagatgatg atcgcaatta
    28321 ataatgggaa caaaacgagg atcaaatgtc gtttcgttaa tttcattttt tcacctcttg
    28381 tattcgattg gttctaatgt tatcaaaaat tttatcaaaa aggtagtctt tatgaaaaaa
    28441 gaaaacaatt attttcctaa ttttataaag aaaaagagaa taagctgcaa gcctttcagg
    28501 ctgagggctt atcctctttt cgactaatct acataataca tgattgcaaa cgcgtcttta
    28561 ccagtatgcg tagcgataac cggattcgta tgcagtacag ggatatgcat gtccgggaat
    28621 aattcttgca aaccctcttt gaattcttgc gccaattctt ttgcatccgc atgtgaaata
    28681 ccgatttgtc gcacatttgg caattctttc agttcatttt tcaaattatt aaaccattta
    28741 tcgaacgttt tctttcctcg ccccttagtt acagggatta attcagaatg ggcgaaattc
    28801 atcaccacgc gtatgttcaa aacactagac agcaaaccag ttgttcggct gattcttcca
    28861 ccttttacca agttatctag tgtggatatt ccgatgtata attttgtatt gtcttgtact
    28921 tttttgactt cttcaaggat tttctctact gttttacctt cttttgctaa ttcagctgct
    28981 cgaattacct gaaaagataa tccttggtca gtggtatcac tgtcgataac cgttactttc
    29041 gtttttgtta gattactggc ttgtcttgct gcttctactg ttccactcaa gccttttgtc
    29101 atatggatcg aaatcacttc actgccgtct tctcctagct catcatacat cgagatgaat
    29161 tctccaattg gtggttggct tgttttgggc agattttttg ctttcgccat catttccata
    29221 aatctttcgc cgtctagttg gtcatcatcg ggatatactg ttccgtcgat catgatggat
    29281 agcggcatga cacgaatgcc taaagcatcg cgtacatttt tttccatcgt acatgaagaa
    29341 tctgttacga tttttacatt tgtcattatt ttctctctct ctttctttaa caagatgcct
    29401 tattcatgtt aaactacatg taagacaatt tctattttta gtataacaga caaataatga
    29461 tttttcatta attacaccta gtaaaggagc cgttttcatg gaaaaaacga aatttaatcg
    29521 aacgtatgaa atattaaatg aagtgtttaa tgcagtcacc catggaattg ggactggatt
    29581 gagtatcgcg ggactagtgg ttcttttagt aaaaggtgcc cacttgcatt cctccctcca
    29641 tattgtctct tatgctatct atggatcgat gatgattctt ttatttttaa cgtctacttt
    29701 gtttcattca ttgattttta caaaagcaaa aaaggtgttc caagtattcg atcatagttc
    29761 gatttttctt ttgattgcag gaagttatac tcctttttgt ttgctgagta tccgaggatg
    29821 gctaggttgg actttatttg tattaatctg gttgtttgcg attcttggca ttatatataa
    29881 agcgttgacg ttgcataaac gggagagagt atcaaaagta tctacgatca tctatatttt
    29941 tatggggtgg ctctgtgtcg tggctgctgt tcctctttat cactctcttg gaatgactgg
    30001 tgttattttg atggtagcag gcgggctttc ttacacgata ggcgcattct tttatagctt
    30061 gaattctatc cgctatatgc atgttgtttg gcatttgttt gttatgttag gtgcaggttt
    30121 tatgtacttc tctgttttat tctttactta ataaaaaaaa taaagctatg gatgggacag
    30181 ctctaaataa cagctagtct atccatagct tttttatatc gtcaattcgc ctgtcccgct
    30241 ttttacagga ttctcattac gctgatacgt ttcaaattga tgcggataac gatttttttc
    30301 atccatttct ccttgactag tattgatcag tgaccaatca gaccagtcaa caggtggaaa
    30361 ataagcatct ccatcgaata catgatggat gactgtacgg tataatatcg tacaaaatgg
    30421 cagaaattct tgataaacag ctgaccctcc agcgatgaaa aagataccgt ctgtttcttt
    30481 ttccagagca agcacgtctt ccacactatg catgacatgc acgccttctg ctttatagga
    30541 agaatctctc gtcaaaacaa tcgtctgacg attcggcaac ggacggctac ccatcccttc
    30601 gaatgttttt cgtcccatca ctagtgtatt tgcttctgtc atttgtttga agaatttcag
    30661 atcatttggc aaacgccaag gaagacggtc ttcttttcca atcaatccgt tttcatcctg
    30721 tgcccaaatt gcagctaaca ttttctcatc ctttctgatt ctaaacagcg ataggagctt
    30781 tgatcgccgg atgtgggtca tatccttcta attggatatc ttccatctca aaatcaaata
    30841 ctgactgctt ttcctgattc aaaactaaag tcggaaatgc gcgtatttct cggctcaatt
    30901 gttctttcat ttgttcgata tgattgatat aaagatgagc atctcctaat gtgtgaacaa
    30961 attcgccaac cgctaaacct gtttcatgtg caattaggtg agtcagcaac gcataacttg
    31021 caatgttgaa cggaacgcct agaaacacat ccccactgcg ttgatacaat tggcagctta
    31081 gccgtccctc ttgaacataa aattgaaaca tcgtatgaca aggaggcaaa gccatgctag
    31141 gaacatcttc cggattccat gcagaaacga tcaatcttct agaatcagga gtctttttga
    31201 ttgcttcgat cacttgtttg atttgatcga taaagccacc gtcttttgtt tcccagtgac
    31261 gccattgata gccgtagatg tgtccaagat cgccgtatgt ttcagcaaag gaatcatcgg
    31321 ttaggatctt ctcgcaaaaa agcttgctct gctttttata ttcttcattg aattcaggat
    31381 ctgtcaaaca tctatggcca aaatcagtca tatctggtcc attatagtct ggacttttga
    31441 tgtagcgttc aaatgcccat tcatcccaaa tatggttttt attttgtaat agatagcgga
    31501 tattcgtatc tccttttaaa aaccaaagca attcgctttt gatcaatcca aaaggtactc
    31561 gtttcgttgt taacaaagga aacccttttt gcagatcaaa ccgcatttgg tatccgaata
    31621 agcttaatgt gcctgtgcct gttctgtctt ctttacgatg cccttcttcc aacaattttc
    31681 ttcctaagtc aagatacgct tgttccatcc tttttcctcc taatcttcta cccattcact
    31741 caagtattcc caccgtgcca ttttttcttc aagttgtgct tctgtttcag atacgtcgtt
    31801 ttgcaattct tgtaatcgag tgaaattatc tccttgatga ttcatctctt cttggagcaa
    31861 tgagattttt tcttcaagtt ctgcaatctc atcttcaatc gtttcccatt ctttttgttc
    31921 catgtaagat aatttcttct tttcagcagg ttccttgctc tgtatttttg gtttcgcttt
    31981 ttcagcaggc tgctgggtct ctttttgctt cagtaaataa ctggacatgt ttccgtaata
    32041 aagttcttgt tttccgtttc cttggaatac taataactta tctgctacct tgtccaagaa
    32101 ataacggtca tgggaaacag tgatcacagc acctggaaaa cttctaaaat aatcttccaa
    32161 aatcgtcaat gttgctatgt ccaaatcatt ggtcggttca tccaataata aaacattagg
    32221 ttgctgaatc agcagtttca acaaaaataa ccggcgtttt tctccgcctg aaagtttgcc
    32281 tatcagtgtc ccatgcataa atcttggaaa taaaaatcgt tcaagtaatt ctgctactcc
    32341 gatttgactg ccatctgctg tttttgcttc ttcagcagct tcttgtaagt aagcaatcat
    32401 ccgtttatct ggtgccattt cttcattttc ttgtgtataa tacgcaagat gaaccgtttc
    32461 accgatagac attgtaccgc tatccagggg aattctgcca gctagaatat taagcaatgt
    32521 cgattttccc gcaccatttt taccagtaat acctagtctt tcccgagatt gaatcaataa
    32581 atctaaatgt tctagcagtg tttggtcatt tatacggtaa ctgccatctt tgatttccag
    32641 tacttttttc cctaaacgtt gtgtcgctag gttcagctct aaatcatctt cttggtttac
    32701 ttggtacaag ttctccttta gatcttcgaa acggttgatc cgtgcttgct gcttggtgcc
    32761 acgtgcctgt acgccagccc tcatccaagc taattcctgt ttataaagcc gcttgcgctt
    32821 ttcttcttgt tctacttcta cacgatcacg ttctgctttt tctaagacgt aagcttcata
    32881 atttccttta tactcgtata attttccaaa tgaaagttcg aagattcggt ttgctactct
    32941 atctagaaaa taacgatcgt gggtaaccat caatagtgcg ccacggtatt gtttcaaata
    33001 gttttccaac cactcgatcg cttcataatc taaatggttt gttggttcgt ctagtaatag
    33061 taaatcgggt tcatcaatca acacttgcgc cagactaact cgttttttct gaccacctga
    33121 taaagtactg atttttttat ctaattcact gattcctaat ttttgcaaaa taatctttgc
    33181 gttggtatct gtagtccaag catcttcttt attcatttgt tcttctgctt tagcataacg
    33241 tttttgcaca tcagggtctt ctccgttttc ccctagttcg atcaatgctt cctcatatgc
    33301 tcgaacagtt tggatcaagg ggctgtttcc ttgaaagact gcttggagaa cagttaattc
    33361 atcggaaaat tcagctgctt gagaaagata accaatacgg taatcagttg gataaaacac
    33421 tgtttgccga tcaccgtcgc tgctatcgat accggcaata atatttaaga gacttgtttt
    33481 acccgtcccg ttcgtcccaa tcaacccgat acggtctttt tcgtggacca aaaaagaaat
    33541 ctggtcaaac aaatcttttt caccataagt ttttttgagg tcagttactt ttaattcttt
    33601 caacatgttc cctccttatc ttggatattg tatcataaaa atagtgaact tcaggaaaat
    33661 ttttttggta tttgttcttt ttgtgttctc aaaaaaagaa caggaccgat tcgatcctgt
    33721 tctgatatgt tttgtttttt ataaaacttg aaaattttta c
//
LOCUS       DAIGTA010000028        33288 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.028, whole genome shotgun sequence.
ACCESSION   DAIGTA010000028 DAIGTA010000000
VERSION     DAIGTA010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.028"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            134..409
                     /locus_tag="NOB43_001422"
     CDS             134..409
                     /locus_tag="NOB43_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HCI0982287.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            415..1182
                     /locus_tag="NOB43_001423"
     CDS             415..1182
                     /locus_tag="NOB43_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HCI0982288.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            1350..3179
                     /gene="typA"
                     /locus_tag="NOB43_001424"
     CDS             1350..3179
                     /gene="typA"
                     /locus_tag="NOB43_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HCI0982289.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            3440..5212
                     /gene="recQ"
                     /locus_tag="NOB43_001425"
     CDS             3440..5212
                     /gene="recQ"
                     /locus_tag="NOB43_001425"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HCI0982290.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            5326..5628
                     /locus_tag="NOB43_001426"
     CDS             5326..5628
                     /locus_tag="NOB43_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HCI0982291.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            5631..6794
                     /locus_tag="NOB43_001427"
     CDS             5631..6794
                     /locus_tag="NOB43_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI0982292.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            6820..10248
                     /locus_tag="NOB43_001428"
     CDS             6820..10248
                     /locus_tag="NOB43_001428"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HCI0982293.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            10269..11393
                     /locus_tag="NOB43_001429"
     CDS             10269..11393
                     /locus_tag="NOB43_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982294.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            11383..11820
                     /locus_tag="NOB43_001430"
     CDS             11383..11820
                     /locus_tag="NOB43_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0982295.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            11804..12142
                     /locus_tag="NOB43_001431"
     CDS             11804..12142
                     /locus_tag="NOB43_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HCI0982296.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            12261..12821
                     /gene="rsmD"
                     /locus_tag="NOB43_001432"
     CDS             12261..12821
                     /gene="rsmD"
                     /locus_tag="NOB43_001432"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HCI0982297.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            12818..13309
                     /gene="coaD"
                     /locus_tag="NOB43_001433"
     CDS             12818..13309
                     /gene="coaD"
                     /locus_tag="NOB43_001433"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCI0982298.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            13299..14342
                     /locus_tag="NOB43_001434"
     CDS             13299..14342
                     /locus_tag="NOB43_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HCI0982299.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            14501..15229
                     /locus_tag="NOB43_001435"
     CDS             14501..15229
                     /locus_tag="NOB43_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCI0982300.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            15345..15590
                     /locus_tag="NOB43_001436"
     CDS             15345..15590
                     /locus_tag="NOB43_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0982301.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            15587..15805
                     /locus_tag="NOB43_001437"
     CDS             15587..15805
                     /locus_tag="NOB43_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCI0982302.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            15941..16480
                     /locus_tag="NOB43_001438"
     CDS             15941..16480
                     /locus_tag="NOB43_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HCI0982303.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            16473..18746
                     /locus_tag="NOB43_001439"
     CDS             16473..18746
                     /locus_tag="NOB43_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HCI0982304.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            18784..19830
                     /gene="holA"
                     /locus_tag="NOB43_001440"
     CDS             18784..19830
                     /gene="holA"
                     /locus_tag="NOB43_001440"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCI0982305.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(19919..20173)
                     /locus_tag="NOB43_001441"
     CDS             complement(19919..20173)
                     /locus_tag="NOB43_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCI0982306.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(20573..20842)
                     /locus_tag="NOB43_001442"
     CDS             complement(20573..20842)
                     /locus_tag="NOB43_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982307.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(21312..21767)
                     /locus_tag="NOB43_001443"
     CDS             complement(21312..21767)
                     /locus_tag="NOB43_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCI0982308.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(21905..23833)
                     /locus_tag="NOB43_001444"
     CDS             complement(21905..23833)
                     /locus_tag="NOB43_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI0982309.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(24030..24863)
                     /locus_tag="NOB43_001445"
     CDS             complement(24030..24863)
                     /locus_tag="NOB43_001445"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCI0982310.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(25055..25759)
                     /locus_tag="NOB43_001446"
     CDS             complement(25055..25759)
                     /locus_tag="NOB43_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0982311.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(25782..26408)
                     /locus_tag="NOB43_001447"
     CDS             complement(25782..26408)
                     /locus_tag="NOB43_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0982312.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            26734..29109
                     /locus_tag="NOB43_001448"
     CDS             26734..29109
                     /locus_tag="NOB43_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCI0982313.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(29133..29624)
                     /locus_tag="NOB43_001449"
     CDS             complement(29133..29624)
                     /locus_tag="NOB43_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCI0982314.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            29811..30731
                     /locus_tag="NOB43_001450"
     CDS             29811..30731
                     /locus_tag="NOB43_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0982315.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            30885..31229
                     /locus_tag="NOB43_001451"
     CDS             30885..31229
                     /locus_tag="NOB43_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HCI0982316.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(31419..31919)
                     /locus_tag="NOB43_001452"
     CDS             complement(31419..31919)
                     /locus_tag="NOB43_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0982317.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            32447..32530
                     /locus_tag="NOB43_001453"
     tRNA            32447..32530
                     /locus_tag="NOB43_001453"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32481..32483,aa:Leu,seq:cag)
     gene            complement(32854..>33288)
                     /locus_tag="NOB43_001454"
     CDS             complement(32854..>33288)
                     /locus_tag="NOB43_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCI0982318.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11010 a         5771 c         6783 g         9724 t
ORIGIN      
        1 aaaaatcagt tgcgttttgt tttttagaat tatcaataat attattatgt aaacttaaaa
       61 atatgacaac ttcttggttt attaccactt cctatgctac actgaagagg aatatgaaat
      121 aggagagttg aagatgcaag aatatcagta tccacttgat ttagattgga caacagacga
      181 aatggtcatt gtaatgaaga tgtgggaaga tctggaacgt gcgaatgaaa aagggataaa
      241 caatgaagct tttttgaaga cttatcagca gtttaaaact gttgtcaaat ccattggtga
      301 ggaaaaacga ttgggacggg aatttgaaaa agcttccggt tattctttat atcgtacagt
      361 gcagcaagca aaaaaaaatc caaacaaaac tttgagaatg aacgggtgag ataaatggaa
      421 cagatgattg atcatatcaa gtcctggctt gaagaagctg gtgagaaaat caaatcttct
      481 caacaaacat taacaatctc gcaaaaatca aatcgaacgg atctagtaac aaatgtcgat
      541 cgaaacatcc agaattttct aatcgaaaaa atccattcct ttgatccaga ggcgaaaata
      601 ttggcagaag aagaagggtg taatcaatta tcggatctcg atggaagagt ctttatcatc
      661 gatcctattg atggcacctt gaattttgtg attgaagggg aaaatttttg tattatgctc
      721 gctgtttatg aatccggcgt tggaaagctt ggtttcattt atgacgtgat gagaaatgaa
      781 cttttttggg gtggaaaagg aataggcgtg tataaaaatg atgagccatt gcctagacca
      841 gcaaataaat ccttatcgga aggcttactt ggtgtgaata gttatctttt cggtcataat
      901 aaatatggaa tccgagaaat tgcggaaagc agcatgggga cacgtatgta cggatgcgct
      961 ggtcttgaac tagtggcaat cttgaaagga aaccacattg cttatatttc aaaccttagc
     1021 ccttgggatt atgcagcggg aaatgtctta ttggaagagt ttggtatggt aacaagcggt
     1081 ctttttggta ctcctttgac atttgaaaaa agggaatact atttagcagg gacttcttgt
     1141 gcatatgcag aaatcgcaga ccttttgaaa aaagaaggct gaaaaaaagg tagaaatcat
     1201 tcacaaaaat gataaaaacg agcaaaagat taattttctc gaaaaaatga aaacatttta
     1261 ctatatttca tgaaaaaagt ctgctataat tagcagtcga gtaaaatttg ccctgtcata
     1321 aagaaccaat aaaaaaggag ttagttacat tgaattatag aaacgatatc cgtaacgtcg
     1381 caattattgc ccacgttgac cacggaaaaa caacattagt tgatgaacta ttaaaacaat
     1441 cagatacatt agacgcacat acgcaattgc aagaacgtgc gatggactca aatgcgctag
     1501 aaaaagaacg tggtatcacg attttagcca aaaacacagc tgtagactat aaaggtattc
     1561 gcgtaaacat catggatact ccaggacacg cggacttcgg tggcgaagta gaacggatca
     1621 tgaaaatggt tgacggcgtt gtgttggtcg tagatgcgta tgaaggaaca atgcctcaaa
     1681 cacgttttgt attgaaaaaa gcactggaac aacatatcac accaatcgtt gtcgtaaaca
     1741 agattgacaa accttctgct cgtcctgagc atgtcgtaga tgaagttctt gaactattca
     1801 tcgaattagg agcagatgat gatcagttag actttcctgt gatttatgca tctgcactaa
     1861 atggtacgtc aagcttgtca gatgatccag cagatcaaga accaaccatg gcacctattt
     1921 ttgatacaat tattgaaaaa atccctgctc ctgtcgataa cagcgacgaa ccattacaat
     1981 tccaagtttc attacttgac tacaacgatt atgtaggtcg tatcggaatc ggacgtgtat
     2041 ttagaggaac aatcaaagta ggagaccaag tagcattaat taaattagac ggaacagtta
     2101 agaaattccg tgtaacgaaa ttatttggtt tctttggact aaaacgtcta gagattcaag
     2161 aagcaaaagc tggagacttg attgctgtct caggtatgga agatatcttt gtcggtgaaa
     2221 cagttactcc tgtggatcat caagatgcgt tacctatcct tcacattgac gaaccaacat
     2281 tgcaaatgac tttcttagtt aataattcac catttgccgg tcgagaaggt aaattcgtaa
     2341 ccgctcgtaa gattgaagaa cgtttgatgg cagaacttca aacagatgta tccttacgag
     2401 ttgaaccaac aaactctcca gatgcatgga cagtttctgg tcgtggagaa ttgcatttgt
     2461 ctatcttgat tgaaaacatg cgccgtgagg gatacgaatt gcaagtatct cgtccagaag
     2521 ttattgaaaa agaaatcgac ggtgtaaaat gcgaaccgtt tgaacgcgtg caaatcgata
     2581 caccagaaga atatatgggt agtgttatcg agtccttgag cttacgtaaa ggtgaaatgc
     2641 aagatatggt ccatacagga aacggacaaa tccgtttgac attcttaaca cctgcccgcg
     2701 gtttgattgg ttattcaact gaattccttt caatgacacg tggttacgga atcatgaacc
     2761 atacttttga ccaatatctg ccaatgcttc ctggtcaaat tggcggacgt caccaagggg
     2821 cgcttgtttc gatcgataca ggaaaagcaa cgacttattc tatcatgagt atcgaagaac
     2881 gcggtacagt cttcgtagaa ccaggtacag aagtatatga aggaatgatt atcggggaaa
     2941 acagccgtga taatgatttg actgtcaaca tcacgaaagc aaaacaaatg acaaacgtac
     3001 ggtctgctac taaagaccaa acatctgtca tcaaaaaacc aaaacaattg acgttggaag
     3061 aatctttgga attcttgaat gatgatgaat attgcgaagt aacaccagaa agcattcgct
     3121 tgagaaaaca aattttagag aaaaatgctc gtgaaaaagc atctaaaaag aaaaaataat
     3181 ctgtaaaagg atgaagagag aaaccagctt gttataaaaa atagctggtt tctttttttg
     3241 tccaactctt ttctgtggag aagtcatctt tgtcaatgga cataaattca gaaaatacgc
     3301 cgaaagacgt ttaaaagact tttaaaaaac ttatttctag agagtttttg tttcataata
     3361 agataatgtt tcacgaaagg agatcaactt gtccttcgaa gaaaatcgaa gtaaaatggc
     3421 aagagaaagg agcgggaaga tgaacgactt attaaaacaa tactttggct atgatgagtt
     3481 tagacctggt caaaaagaaa ttatccagaa agtcattgat caggaaaatg tattaggaat
     3541 catgcctacc ggaagtggga aatcaatctg ttaccagctt ccagctttac tattagatgg
     3601 gcttactgtg gttgtgtccc ctttaatctc tttgatgaag gatcaggtgg acgcggcgaa
     3661 tcaattaggt atacccgcca cttttatcaa tagctcgtta gatggttacg aaacagctag
     3721 acgcttccaa gaaatcgata gacagcagta ccgtttactt tatatcgctc ctgaacgttt
     3781 tatcatgccg gattttatcc aagcaatgaa gcgatggaac gtccgtatga tcgctattga
     3841 cgaggcacat tgtatctctc agtgggggca tgatttccgc ccaagttatt tacagatggc
     3901 gaaccagcta gatcaactgc caaatcgtcc tgtaattgtt gctttgacag ctacagcgac
     3961 tgtgcaagta gctgctgaca taaaaagact tttaaaaatt ccagaaaaca accatattca
     4021 gactggtttt gaacgagaaa atctacgatt tcaagtaatt aaagatcaaa aaaaagaaca
     4081 atatctaatc gaatatttaa agatcaacaa aaatcaatct ggtatcattt atgcagcaac
     4141 gagaaaagaa gtagaccgtc tctatcattt gcttaaaaaa ttcgattttt ccgtgggtag
     4201 atatcatggt ggtctaaatg agaatgagcg aacagaaatg caagaagcct ttttatacga
     4261 tcgcttgcag ctgattgtag cgacaaatgc atttggtatg ggtataaata aaagcaatgt
     4321 ccgttttgtt atccattatc aaattcctgg ctctctagaa gcatactatc aggaagctgg
     4381 tcgggcggga agagatggtc tttccagtga agccatcctg cttttctctc ctcaagatat
     4441 ccaagtccaa aagtttttta tccagcagtc ccaaagagaa gaagggcaaa agcaaaaaga
     4501 atatgaaaaa ttaaaagcga tgacagaata cgtgtatatt gagtcctgtc ttcagcaata
     4561 catcctaaac tattttggcg agacaagcag tccgtgcaac cgttgtggta actgtttaga
     4621 tgacagagaa atagtagaag taacgacaga agcacagatg gttctttctt gcttaaaacg
     4681 tatgggtgag aactatggta aacaaatgct gatgaaagtc ttagcaggat cgaaagaaca
     4741 aaagctgcaa gctttaggtt ttggacattt atctacctat ggactgatga aaaaccaatc
     4801 gcaaaaagaa acgatgcagt taattgaata tttgatatcg aatggctatc ttctgaccat
     4861 caatggtgag tatcctgttt tgaaagtaac agaaagaggg atacaagtat tgaaaggaca
     4921 agaatctgtt tatcgaaagg aacccaagaa agtccagcag ctatcggatg aagaaaccga
     4981 tacactattt gaagtgctgc gggaactgcg aacggatcta gcatcagaag caggcgttcc
     5041 cccgtatgtc gtattttcag attccacatt gaaagaaatg agccgaatac gtccatcaag
     5101 cagattggag atgcttcaga taaaaggagt tggccaaagc aagcttgata aatatggcga
     5161 agccttttta tctcggataa aaaatgcgga ctctaacgtt ctggataagt agaaagaacg
     5221 aatacgtaaa aatgaataaa aacaactggt taaatctgtt ttttttgctc cttatgaaaa
     5281 tcaaatatgt tataattaag gaattagaat gggaggtaag cacagatgga ttctttgtcg
     5341 aaaaaacttg cgatccaagt attaaatgat gaagcagaac ggatcaaacg attaatccga
     5401 aatcaaaaca acagtctctg tatctcacaa tgcaaagcct tcgaagaagt ggtagataca
     5461 cagatgtacg gcttttcccg gcaagtcggt tttgctgtcc gtataggagt aatcggaaag
     5521 aacgagggcc agctgatgtt aagtgagcta gaacgagaat tgaatcagtt atatagtgag
     5581 gtttaccaag aaatttatga taaaaaagaa gttggcaagg aggaatagac ttgcctaaga
     5641 aagtgaaaaa aaggcatcta ttagactata gcatcttgat tccctattta attttatgtg
     5701 tattgggatt gatcatggta tatagttcta cgtcgtatct attattagaa aacggacaaa
     5761 atccgtccgc atcagtcatt aaccagagta ttttttgggt gcttagcttg attgctatcg
     5821 cactacttta taaaatgaaa acagatgttt tgaaaaacca gcgtttgatc atggcagcca
     5881 tcgcagtttt gacgattttg ctgctgattg ttgtgttttt tggtaaggag atcaatgggg
     5941 cgaaaggttg gctgcaaatt gcaggattct cgatccaacc tgccgaatac ctaaaaatca
     6001 tttctatctg gtacctgtct ctgactttat ctaaaagaca aaacagtgta caaaaagatt
     6061 ttcttgggac tgtgaaacgt ccacttgcaa tggttatcgg acttactgca ttagtcgcta
     6121 ttcttcccga ttttggtaat gcggcagtta tctttttgat tattttggtt ctgcttttag
     6181 ccagcggagt caattatgtg tatactttga ttgtaggagt aggaggcttt tgtctaagta
     6241 cttttacgat ctggctgatc aatatcacaa acggaaagat cttacccgga cgtttacagt
     6301 atatctataa tcgatttgct atttaccaaa atcctttctc agacgaatta aataaagggc
     6361 atcaactagt caacggctac tatgccatgt tcaacggagg actatttggc aggggattag
     6421 gtaacagtat ccagaaaaaa ggatttttac aagaagcaca aaccgatttt atttatgcaa
     6481 tcgtagtgga agaactggga gtgattatgg ggattttgat attagcgttg ctattcttta
     6541 tgattgtgcg cattgtcctt gtaggtatcc gttcaaaaga tccgttcaat tcgcttttgt
     6601 gcattgggat cggcgcaatg tttttgatcc aagtatttgt caatcttgga ggaattactg
     6661 gcgttattcc tttgacaggg atcacgttcc catttttaag tcaaggaggc tccagtttgc
     6721 tgatgctttc gatttgtgtc ggctttgtcc tcaacatcag tgcggatgaa aaacgcaaga
     6781 gcttaggttt ataataaaaa aagatgtagg agtggttcga tgaaaaaagt tttagttgct
     6841 aacaggggtg aaatcgctgt acgtgtattt cgtgcttgta cagaattagg aattaaaact
     6901 gttggaatct atgcagaaga agatgaatat tccgtacacc gtttcaaagc ggatgaagca
     6961 tatttagtag gacaaggaaa aaaaccgatt gatgcgtatc tagatattga agggatcatt
     7021 tctatcgcga aagaatgcgg agctgacgct attcatccgg gttacggtct tttgtcggaa
     7081 aacttgaatt ttgcgcaacg gtgcgaagaa gaaggcatca tttttgttgg acccaaactg
     7141 catcatttag atatttttgg agataaaatc aaagcaaaag ctgcagctat cgaagcgggg
     7201 attgcttcga ttccaggcac agatggacca atcgcttcta tagacgatgc cttggagttt
     7261 gcgaaacaat acggttatcc gattatgatc aaggcagctc taggcggcgg cggacgcggc
     7321 atgcgtgtag ctcacgatga aaagagtgca agagagggct acgaacgtgc gaaaagcgaa
     7381 gcaaaagcag cctttggtag tgatgaagtg tatgttgaaa aatacatcgc taatcctaag
     7441 catatcgaag tacagattct cggggatacg catggaaacg tcatccatct ttttgaaaga
     7501 gattgttctg ttcagcgccg tcaccaaaaa gtagtagaag tagcgccttg tgtctctatg
     7561 aatgaacagc aacgtcaaaa aatctgccag gcagctgtcc aattgatgaa atatgtcggg
     7621 tatgtcaacg caggtacagt agaatttctt gttgaaggag atgattttta ctttatcgaa
     7681 gtcaaccctc gcgtccaagt ggaacatacg atcacagaaa tgattacaga tattgatatc
     7741 gtaacaacgc aactgttgat tgctcaaggt ttggatctgc ataaagaaat cggattgcct
     7801 cagcaagaag gaattaaatt aaatggttca gccattcaat gccgaatcac tacagaagac
     7861 ccgttgaata actttttacc agacacaggg aaaatcgata cgtatcgttc acctggtggt
     7921 tttggcgtac gtctggatgt cggaaatgct tacgcgggct atgtagtgac accgtatttt
     7981 gattcattgc tagtaaaagt atgtacgcat ggtgctacct ttgaaacagc cattcagaaa
     8041 atggaacgtt gcttgaaaga atttagaatc cgtggagtga aaacaaacat tccatttatg
     8101 ctcaatgtca tcacacatcc tgaattccaa tcaggaaatg caaaaacaac cttcattgat
     8161 agtacagcaa cattatttga atttcctcga ctacgagacc gcggaaacaa aacgatgaaa
     8221 tatatcggtg aaattactgt gaatggtttt ccaggtatcg aaagtggcga aaaaccattt
     8281 tatgaagaac cacgtatgcc taaagatcta atcacaagaa ctgattacgt aacggctaag
     8341 aatgtattag atgcgaaggg tgccgatgct ttggtcgaat ggatcaaagg acaggaaaat
     8401 ttgttgttga cggatacgac atttagagac gcccatcaaa gtctgctagc aactcgtgtt
     8461 cggacaaagg atttcaagca gattgcacgt ttgactggag aaggtcttcc tgaactcttt
     8521 tcaagtgaga tgtggggggg agcaacattt gatgtggctt accgcttttt gaatgaagat
     8581 ccttggcaac ggttgagaaa aattcgttct ttaatgccta atacgttgct gcaaatgctt
     8641 ttcagaggtt caaatgccgt tgggtattct aattatcctg acaatgtatt ggtggaattt
     8701 gtcaaagaag cagcagcgca aggaatcgat gtatttcgaa tctttgatag tttgaactgg
     8761 actccacaaa tggaaaaaag tatccaagct gtacgggata ctggtaaaat cgcagaggca
     8821 gctatttgct atactggcga tatcaacgat ccaagtcggg caaaatacaa tgttcagtat
     8881 tataaagaca tggcaaagga actagaacaa ctgggtgcgc atatcattgc aatcaaagat
     8941 atggctgggc tgcttaaacc gcaggcagct tatcgtttga ttagtgaatt gaaagaaacg
     9001 acagatctgc caatccatct gcatactcat gataccagcg ggaatggaat catcacttat
     9061 tctgctgctt caaaagcagg agtagacatc gttgacgtgg caatgagtgc aatgagtggg
     9121 aatactagtc agcctagcat gagcagcttg tattatgcac tggtcaatgg tccacggctg
     9181 ccagaaatca cgattgaaaa tgcacagaaa ttaaaccatt attgggaaga tgtgcgcatg
     9241 tattacaaac cgtttgaaaa cggcttgaat gctcctgaaa cagaagtata tatgcatgaa
     9301 atgccaggag gacagtattc gaatctacag caacaggcaa aagctgtcgg attaggtcat
     9361 cgctgggatg aaatcaaaca aatgtatcat actgtcaact tgatgtttgg cgatatcgtt
     9421 aaagtaactc catcatctaa agtagttgga gatatggcac tatttatggt ccaaaatgat
     9481 cttacagaag aagatattta tgaaaaaggc gaaacactaa gtttccctga atctgttgtg
     9541 actttcttcc aaggagaact agggcaaccc gttggcggat ttcctaaaaa attgcaaaag
     9601 attattctta aaggcagacc tgcattgaat gaacgtccag gtcttttggc tgaatcagtc
     9661 gacttcaacg aagtaaaaaa agaattggca gaaaaaattg gctatgaacc aaaacaagac
     9721 gaagtattaa gctatttgat gtatccgcaa gtctttttgg actatcaaaa agcatataat
     9781 caatttggcg atgttacatt actggacaca ccaacatttt tccaaggtat acgtttgggt
     9841 gaaacaatca atgtacaaat cgaacgcgga aaaacgctta tcattcgttt agatgaaatc
     9901 ggagaacccg atatcgaagg gaatcgcgta ctgttcttca atttgaatgg acaaagacgt
     9961 gaaatcacta tcaaagataa ttcgatcatc agtacggtcc aaacccgatt gaaagctgaa
    10021 ccgacaaacc gagaacaaat tggagcaacg atgtctggtt ctgttttgga tgtattagtg
    10081 aaaaaaggcg ataacgttaa aaaaggtgat acgttgatga ttactgaagc gatgaaaatg
    10141 gaaacggcca tcgaagcacg ttttgacgga gaagtcgcac atgtatatgt gtcttcagga
    10201 gacactattt cgtctggtga ccttttgatt gaagtgactg agaaataata agcgaaaggt
    10261 ggggaaacat gaaaagactg ggtttgtttt ggctgattct gctattagtt attgtggcat
    10321 tctacatgga accagtcttg tttccgccaa aacttgaagt gaaggaaaac tctgatcaac
    10381 aaatatcaaa ccaaatgaca acgtggaaat accaggagct taaagcaact ggtttttcta
    10441 cttatatcgg aaaaccgatc gatcagctgg aaaaggattt tggccaagcc tatgatcgat
    10501 taactagcgg atttggtttt gaaacaagat attatgaaaa taaagctagt catctcacat
    10561 ttgaagcgaa catccaagac agcagagtca caactgttaa agtactgcaa acagggcctg
    10621 ctgatatcgc gccgttttat ttagggatga cgatgcaaga tcttacgaaa atcactacta
    10681 tctatactaa tttcactttt gagtaccatg atacagaagt tggaatcgaa ctaatggaag
    10741 aggatatgaa ttatcgtccg ctaattgctt ttgataacga cacttttgct attttatttt
    10801 ttgatcaaac aacaaacggc ctattttcag ttgtgtattt agataaagat agtcttttga
    10861 aactattgcc atatcaagtg tttggtgaag gccttccaca ttatcaagca gataaatcgg
    10921 ctgattggga atcaatcaat cgcgttaaag aacgaaaaag tacgacttta ttaaatatgc
    10981 ttagaagaga agacgaactt cccatataca atcaaacact tgcctttcaa aaccacagtc
    11041 agctgctact acatgatttt ttgacaaggc ctgaggaaat attgtcagag gaacgtatgg
    11101 ctgattggca aaaatcgcta ggcagtgctc aaacgacagt gaaattctca ctgacgaatg
    11161 atgaattgga gaagttaatc agtaaacaaa aattagaaaa tactagtggg ctatttattc
    11221 atccggcgat tgacgctact ttttcgtttt tatattggta cagcgatcct tacaaccatg
    11281 accgtttcat ggacccggga acggattctg taggcattgc tttttctaaa gaaaatatgt
    11341 tagtcttatt gcaagaagaa aacggagaaa gtagtgatag cagtgatcgt taacgaagag
    11401 ctgtttcaac tggaggatca atgcctccaa gtcgctgaaa tgataaaaaa gagtaaaacg
    11461 atggcttctt atcttgaaca taaacagtca atggaagaat ctgcaaaagt ttgccagttg
    11521 aaagaagcgt tcttgtctaa gaaagaagca tttgaaaatg tagcggcata tggtgagtat
    11581 gcacctgatt atcgtgaaaa aaaacgagct gttcgaaaag caaaaagaca gcttgatatg
    11641 gatgagcatg ttgcagcttt ccgatatagt gaaacacagc tgcaaagtct gttggatcaa
    11701 attgtccaag tacttgccga agaagtttct aatgaaatca aagtagatgc aggtagcccg
    11761 ttttttgaaa cgaaaaaaca ctttggatgc ggaggtaatt gtcatgcaat tagacaatag
    11821 tgaatttgaa ataacaaaac gacgcgggct gatcgtatgg gtctacagct taaaacaatt
    11881 aaagaatctg aaaaagttcg gcttgttgca ttatgtctca agaagaatga aatatgtcgt
    11941 gctttactta aatgaagaga cattggaaga aacagaagaa cgaatccgta aattacattt
    12001 tgttcgaaac gtagaacgtt cttaccgacc ggatatcgaa atgaattttg ccgaaaaaat
    12061 aggaaacaaa acagtattaa aagacgaagg tttcgaaatt gaagagctaa atacagaaat
    12121 ccgattagct gaacatcttt aaaaatctct tatgagcagt ttttaaataa aaaataactt
    12181 ggataacgat cgatttttga tcattgtcca agtatttttt tggtatacta gtaccagtac
    12241 catttctaag gagtgagtag atgcggataa tatcaggaaa ttatggcggg cgccgtttaa
    12301 aaagtttagc aggggcgaac accagaccaa ctacagataa agtaaaagaa tccatattca
    12361 atatgattgg accatatttt gatggagaga cagtattgga tctgtttgca ggaagcggtg
    12421 gtttagctat cgaagcagta tctagaggct gcagtcatgc ggtatgcgta gacaaaaatt
    12481 accaagcgct aaaaatcatc aaagaaaaca tcgaaattac gaaagaacca gagaaattta
    12541 ccacaataaa acttgatgcg gacaaagcaa tcgaacggct agcagcggag aaacaacaat
    12601 tcgactactt gtttcttgat ccgccatatg caaaacaaaa aataatcgat caaatccata
    12661 aaatggaaga actgggactt ttttctaaaa ccgcagttat cgtatgcgaa acggataaaa
    12721 cagtcgaatt gccagaaact gtggctggat tccatcaaat aagaaaacag atttatggca
    12781 taacggccgt aactatctat agaaaagagg gaaatcaatg aaacgtgcat tattcccagg
    12841 aagttttgat ccttttacaa aaggtcactt agatacggtg gaacgtgcgg ctaaattatt
    12901 cgatgaggta gtaattggtg tttttatcaa tacttcaaag aaaagtttgt ttcccccaga
    12961 agaaagaatg acattgatca caaaagctgt ttctcatctt cctaatgtaa aagtcatgca
    13021 tcaagaaaat caattgacgg tagaaacagc aaaagagatt ggtgcagatg cgttgatcag
    13081 aggcatacga agtatcaaag actttgaata tgaacgagag attgctcaga tgaatcatca
    13141 tctatatgat gaattggaaa ctgtcttctt attagcaaaa ccagaatata gtcacgtgag
    13201 ttccagtatt ttaaaagaag tactgcactt tggcggagat gtgagcagct acttaccgcc
    13261 agtgatcaac gaagctttag ctggaaagcg tgaatcaaat gaaagctaaa caatggttga
    13321 aaacagtact gattatcata tttggaatgt tgatcattgg atttgtagta gttcccttgc
    13381 cgtattatgt agaatcaccg ggagccacga tcgatctgaa agaactaatt acggtcaatg
    13441 ataaggaaga taaaggttct gggtctttct ctcttacctc tgttggtatc aggcaagcta
    13501 caggtttctt agctttaaaa gctaaaatga ccccttttga agaattgatc agtgaagaag
    13561 aattgactgg tggggcgaca aatgaagaat ataatcaaat gcaacagtat tatatggatt
    13621 cttcccaaaa tgcagcaatc gaacaagcgt taaaacttgc agacaagcct tataaaatgg
    13681 aattcaaagg cgtatatgtc atgagtgtag agaaaacatc gaatttcttt ggcaagcttt
    13741 cagttggaga tacagtaaca aaagtagacg ggaaaagctt tcaaagtaca gaagcattta
    13801 tggattatgt aaaaagccaa aaagttggac aaacaatcga aatcagttat ttgcataatg
    13861 gtgaagaaaa aacagcttct ggtgatctga tcgagttacc aacagataaa aaggcaggaa
    13921 taggtatcac gcttactgac cataccgaga tcgaatcaga tacagatgtt cgtattaatt
    13981 ctggctctat cggtgggcca tcagcgggat tgatgttcac tttagaaatc tatgaacaag
    14041 tcactggtaa aaacttgcga catggtaagc aaattgcagg aactggaacg atcaacagtg
    14101 aaggagaagt tggccgaatc ggaggaatcg ataaaaaagt ggcaagtgcg gataaagctg
    14161 gcgtagagat tttctttgca ccagatgata cgatttcaga cgatgttaag aaagaatatc
    14221 ctgaaataaa aaccaactac gaagaagcaa aagctgccgc taaaaaattg aattcctcaa
    14281 tgaaaatcgt accagtaaaa acagtacaag aagcgcttga ctatctagag aaaatgaaat
    14341 gaaactaaat aattaaagag gggttgtgac acgagttctg tcacaacccc tctttttcgt
    14401 caaaaatctt cacgataaaa ataaaaacaa aagaaaaaat tgacgtaatt agatgttgaa
    14461 gggacgattt tgccagagct cactgtttct tcaattttaa atgaaaggag taatgaatga
    14521 tttttactgg tcattctttg aaaaaagaac aatgatagaa aaaatcagca agaaaatact
    14581 agcttcaccc aaattgatca tttggatgtc tatgatagtt cttatctttt gtatcgcaag
    14641 tggtttttta ttatcaaatt tgctatttta tagagaaaca gaagagactg ctgcaaaaga
    14701 aatactttct tcgtttagtt ccagtggaga agatccatca gctgaaggaa acgatgtaga
    14761 agaggatgct cgtccaaagg tcatgtacac cgatatcaaa ggaagtgtga aggagcctgg
    14821 tatctattcc ttttcttcag aagaacgggt ctatgatgta ctaaagcgtg caggtggatt
    14881 attagaagaa gcggatagcg atcgaatcaa cttttctgcg aagatagaag atcagcaagt
    14941 cctatatatc cctgctgtag gtgaagagct gccagaacat cttgatcagt tggcatcctc
    15001 ggaaggaaaa cagcctacag cagattccga gcctcccaaa ataaatatca atacagccac
    15061 tccatcagaa cttcagcaga ttcctgggat cggatcagtc aaagcgcaag aaatcattcg
    15121 atttagagaa gaaaacggat ccttccagaa agtggaagac ctgcaggaga tttctggtat
    15181 cggtgaaaag acagttgaaa aactaaaaaa cttcgttaca attaaataga atgattcaaa
    15241 atcgactggc acgagcaata aatggacgct aatggatact aagaataatc caattctaag
    15301 agcttggcag gacgaggagg tagtattttt ggataggaaa tagcttgatt gttcgcaaag
    15361 aaacattaaa aaaaccaatg ctgaatgtct atctccaaaa taaaatatct gggattcata
    15421 ttatgaatac ggctgtcagc ggcaataaca gtcaagctct acgagaacgc tttgccaaag
    15481 atgtacttag ctatacagca gataaagtat ttattctcat tgggacgaat gatctagcag
    15541 agcataaaca actttctaaa gaaacgtacc aaaaaatctg cagtggatga tagttcagct
    15601 gaaaaaagac tatagttctg atcatgcttt ctttatcacg ccaccagcag tcgatgagac
    15661 aaaacaaaaa tatcggaata acaagttgat caaagaatat atctctgttc tcacagaagt
    15721 agcaaaacgc catgattgtg aagtatcgat ttttatacgg aatttcttga acaaatggat
    15781 tcgaagaatt tttataatgg gctaatggat gacggacttc atttcggcag tgaagggtag
    15841 gatcttttgt cagacaggat gattcgttat atttaaagaa tattttgttt aagcaatgag
    15901 tactttttaa tcaacttgaa aaaacggagg aatataaaac atgttagaaa aatcttcaaa
    15961 agcatgcgat acgaataaag aaaaagttac tgataagtca cataatgaac gcattccttg
    16021 ggaccagtac tttatggctc aggcagtact gttatcttta cgtagtacgt gtacacgttt
    16081 agaagtagga gcgacactcg ttcgagaaaa aaggatcatt gctggcggct ataatggagc
    16141 agtcagtgga gatgtccact gcatagatga agggtgttac gtcgtggatg gacactgctt
    16201 gcgaacgatc catgcagaga tgaatgcact cctacagtgt gcaaaacttg gtatcccgac
    16261 ggaaggttca gaaatctatg tcacacattt tccatgtttg gcctgtacaa aggctttgtt
    16321 gcaagctggt gtgaaaggga tcaattatct ccatgactat cgaaatgatc cttatgccca
    16381 agcgttgatc gaacaattag gtgtatctgt acaccaagtt gctttagact cacagcattt
    16441 ttcaaaactt caaaatgaat taacaggaaa acatgtctag cgttttagaa aggcatgttc
    16501 gaaatcggtt gatttttccg gcaattacgt cgatgattat ctgtttgttg tattacactg
    16561 acaattgggg ttatcgtttg cttcttgccg gaattttttt atggttttcg ctaaaagaag
    16621 gacgttttat cgcgtacttg tgtattttgt gtagcataac ggtatccatt tcttataggc
    16681 tacaagagta ttcattttta gaggaaaaaa caacatctgc gcaaattact gtatttacag
    16741 atacgattcg tgcaaatggt aattttttga caatggaagg aaggttatca gagaataaac
    16801 aaaagctcca gctttcttat caagtaaaca cagaagcaga attgaaaaca tggcttaact
    16861 tccgaggaaa gggaatagaa ttgactgctg aaggcgagtt catctctcca gcaaaaaagc
    16921 ggaatcttta taattttgac caagaagctt acttcaggaa ccatagaatt tctggacggt
    16981 tccaaattca aaagattgaa cagatcacca tgcaaaatca ctggcgaaac tggcttcaga
    17041 gaaaaagagg atcttttatc tcctttgtcc aatctgaatt tccgcaaaaa acaagtgtat
    17101 atattaattc tttattatgg ggctataaag atgcaggatt cagagaacca gaagaaattt
    17161 ttagggagag tggtttgctg catctgttca gtctatcggg tctacacatc caattttatt
    17221 tagggtggct gtattattta tttcgacgta tcggatggcc actacacgtc agtattattc
    17281 cgttgagtct actaactatc tgttatgttt ctattgcagg aagttctatt tctgttttgc
    17341 gtgctagttt gctgttttta ttgcgattgc tagtcaaatt gctgaataag cattattcca
    17401 ccatggactt atttgcagtt gtcttttggc ttcttttact atttgatcct cgatttcttt
    17461 ttcatgcggg tggacagctt agttttttca tgagtttttt gtttatcctg atttcttttg
    17521 atggagattg gttgaaaaaa acggcctctc acgtcctgtt tactatgatc acgatgccgt
    17581 tgattgtatg gcatttttat gagtggccta ttttaggtag tctttttaca ttactgattg
    17641 caccggtatt caagtttctt tttcttcctg gtgtgttatt tctcacactc ttcaatcgct
    17701 ggctgccgga aactttactt ttgctgatag aagagggatt aatcttattt gagcgaataa
    17761 tcgatttttc ttcagggtcg tctctcatta taggacgttt gccccttgtg ctatctggga
    17821 tgtatatttt cggattactg atttgtatgg ataggttgaa agaacaacct gtgaaacact
    17881 tgttttatgt tggtcttttt tcttttattt ttttgacttt gccattttta cgcttttctt
    17941 caacgatcgc ttttatcgat gtcggtcaag gagacagtat ctttttgcaa agtccttttc
    18001 gaaaagaaac gattttgatc gatactggag gtcagttaca ctttgaaaga gaaaagtggg
    18061 cgcaaggtat gatacgtcct cctgctgaaa gaaatatcgt tccatatcta aaaggtcagg
    18121 ggataagtgt aatcgataaa ctcatcttga cacacgacga tacggatcat gtgggagaat
    18181 tacccacgtt atctcagcat tttactatca aaaaaattta tatcggttgg ggcgctggac
    18241 gaaatgagcc attacaaagg catttatctg aagctcaaaa aaatggtact gagatcattg
    18301 aaatcaaaca tggggacagg atcagcggtt attatgatct ttatgtattg actccttttg
    18361 aaaagggaga gggaagaaat gaagattcga ttggtctatg gatggaatat aacaataggc
    18421 gctttttatt tttaggagat ttgaatcaag caatggaaaa acaattgctt ttgatttatc
    18481 ctaatctgaa agccgatgta gtcaaattag gtcatcacgg tagccgtacg tcaagtaaca
    18541 cagattttct ttcccatatt gaagcaaaac atgggattat atcctgcggc gtaaataatc
    18601 gttatggtca cccgcacagc gaagtattgg agacactaga agaaaatcag ataaaaacat
    18661 ggcgaacgga tcaacaagga atgatcacct atcgctggca tccagttttt catcctcatg
    18721 ggctagtgga aacaatgata gactagtaat tctcatctgc tcatggtagg ataatttttg
    18781 aaagtggtga gtaatttgag tatacaagca gagttacaaa aaatacgtaa agaaaaactt
    18841 gcatcttgtt acttgatttt aggaacagaa aagtttctcc aagatcaagt tcggacagaa
    18901 attgtcaaaa aaatccaatt agagggcgaa gatgacttaa attttttaag ttttgacatg
    18961 gaaaatgcaa gtttagatga ggtagtagct gaagcagaga cgttgccgtt tttcggagat
    19021 caacggttag tattcgtaga gaatccttat tttttaacag gtgaaaaagt aaacaatgga
    19081 atcgaacaaa atactgattt attgacggct tatttgaaag aaccattaga atcgactgta
    19141 ttagtattct ttgcgccata tgaaaagttg gatgaacgga aaaaagtaac gaaacaattg
    19201 aaaaaaacag caattatcat caatgtccaa cagttgaatg aaaaagaagt acgtcaatat
    19261 ctgatgaata ccttagagaa ttcctcaatc aaaatggaac gaagtgcaat tgatttattc
    19321 ttgaggttga ccgacttaga tttatccaaa atgatgagag agttacagaa attggtcctt
    19381 tatggacaaa atcaacagca aatcacggta agagaagtag aagaattagt tcctaaaacg
    19441 ttagaacata atatttttga catgacccaa tatattttaa aagggaagac ggaacaagct
    19501 ttgcgtttat acgaagattt agttatgcaa ggggaagaaa caatcaaaat taatgcgatt
    19561 ttgctttctc aattacgttt atttttacag acaaaatttc ttgtaaagat tggttatcag
    19621 caggcaaata ttgctgaaac attgaaaatc catccatatc gtgtaaaact tgccatgcag
    19681 gaagtaaaaa aattcgatga acatttgctg gtacagttgt ttgatcaatt agttgagatg
    19741 gattatcaaa tcaaaacggg acaaatcgaa aaagaattaa gttttcaact attcgttttg
    19801 cgcacagggc agttgttaag aaatcgataa gaagaaagac gagggcaaag catgcgggaa
    19861 ggtcgtttgt ttttgtcctt tttttgacaa ataaaaaaat cggccgaagc cgattctttt
    19921 atttagcgat ttttttgctt aaacgagatt tgtcgcggtt agctttgttt ttgtggatta
    19981 gaccttttga ttcagccata tcaatagctt taacagcttc tttatataac gcatctacgt
    20041 tgtcagcacc tgaagctaca gcatcttcaa attttttgat tgcagtacgc atagcgcttg
    20101 tttgagatga atttttcaca ttagcgtttt cgcttgtacg aacacgtttg attgcagatt
    20161 caatgtttgg cattagtttc acctccgata acttaagttc ttacgcgtgt taccgcataa
    20221 ttcaacattc attattatac ctaaaggcag cgtgctttgc aatatgaaca tgacaagttt
    20281 ttttccttaa cagtctttta ttaggatttt ttttcagtaa aaacggatag tacaagctga
    20341 aaaaaatcaa aaagacgcta ttgtgggagg caatagcgtc aaaccaaact agatttttat
    20401 ttatctattt aaacaaagtt tgaatgggaa tgtttggtac taagttatta tataacaaag
    20461 agaaccgttt gcaaagtttt ttttgaaaag ggatacgatt ccctgttgtt ctttgttttt
    20521 ctattaagaa actgcagtta ttttataacc agtatccttt gatcagtaaa ggctattctg
    20581 gtgtaccgat tattttaatg tattcatcga tattttttat caacattttt tttatgacca
    20641 actggttccg acggttccat ttgccactta cttccagcac atatttattt aggggcaaac
    20701 gtaagatata ttttgccaaa tagcgatctt taagcaggcc attgatcaca cggtcctcaa
    20761 gctgcaagtt gatcccagtc agcatcattg gctgttcttg taaaacgtac gtatcaatta
    20821 aaagaccttc aaaagtttcc acaagcgtct tcctttcttt tcaaagtaac ctgaaaacag
    20881 gcactaattc ttccattttg atattcgttg aagtggatgc gatcattctt tcttttgtcc
    20941 actgtaatct agtataacaa aaaagagcag aagagccaaa aagaaaaaag agcatcgaat
    21001 tctataggaa gtctcattgg cacggcctaa attattacaa aacattgatt aaaaaaagcc
    21061 cctgcatcgc aggagcatcc cctatatcgt tttaataggt caatcaaaaa gcagtatcaa
    21121 acacattttg tatcaaatca ggaaataata gataagctaa gcccagaatc aaaagtaccg
    21181 ctagaagaaa ccagccgatt gttcctatga aatactttaa tttttcgaac attgtatcac
    21241 ctcgttgtca gtatatcacg gatcagtaaa ttgggggtgt taagaatctc ctaaaataga
    21301 caaaatttgt tctattttcc taaagcaaat acttgtaaga tacagtaagt gataccagaa
    21361 gcaatgaccg gtccggcggc gattcctctt aagaagacaa cacctaaaat cgtgccgaaa
    21421 acaagtgcaa cagtgatttg tggatcagaa gcaatcaatc ctacaccctt ggaagataag
    21481 acagccacta gcccaccgca aaaaacagct acccagccaa taggggattt aaaggcttct
    21541 aatagatcac gtagaccgat ttctcctgtt gcgataggga ttagaatagc cgctgtgatg
    21601 atcgtcaccc caatattgat tcctttgcct tgaagccaag ggaaaaagga acgggaggct
    21661 ggtatgagct tcataatcaa aacaaaagct gccgctatca tcagactttg atttttagct
    21721 aaaattgcta caagtaaaat aattcctaaa aaaagccaac tttccatgaa atatattcct
    21781 cactttcttc gaaacaatca taacatgttt ttagaaagtt acaaaagtag gaattcatcc
    21841 ttcaagacct attcataagc tgtttttttc ataaaataaa caaaatcata aaaaaacact
    21901 ttgcttattt gacagaagac agccgcgctt tgtatagtgg acaagactta catttttttg
    21961 aagaatcaga aagatcaggt aaaggtctta gtaaacgcaa gccattcaga ataaccaata
    22021 ttgtgcttcc ttcgtgtcct acaactccaa gaggtagatt taaaaattgc aggaagttag
    22081 aagcaatcaa caagagaata acaagaatcg aaaaaataat attttgtttg atgatccgcc
    22141 gcatttttaa agatagccga tgactgtaga caaatttatt taagtcgctt ttcattaaga
    22201 cgatgtctgc gatatccata gcggcatctg tcccttgccc catagcgaca cctaaagaag
    22261 cggctgctaa agcaggcgca tcattgactc catcaccaac catcgcattt acttggtaaa
    22321 gttcattctc ttttttgact agttgtgttt tttcttccgg agtacagctt gcatagtaat
    22381 gttcaatccc tacttgttca gcaatggcct ttgctgtgcc agaatggtcg ccggttatca
    22441 tacttgtatg gatgttttgg gatttaaagt aggaaattac ttgttgggta tttgcttttg
    22501 gaatatctag cagacctaaa acagcaatta actgctgatc tttagaaaga taaatcacgg
    22561 ttttgccttg attttccaaa cgttcgatca tttccgcaat ctctttgctg attatcatcg
    22621 tctcaggatc atatgcgtgc ttgccaactt tccattgcgc acctaaatag gtagtttgta
    22681 atccaaaacc agtaatttct tctattggta agtattggat ttcttcaggt attgtgcaat
    22741 cgaaatattg caaaatcgca tgagcaagtg gatgcgtcgt tttttgttcc atagcaacaa
    22801 gaagttgttg tgccaaatcc ttttcatcaa agaaaaagct gtcagttaca actggttttc
    22861 ctttagtgag cgttcctgtt ttatcaaagg caatcgcttt taattcagaa agcttttcta
    22921 aatggatacc gcctttgatt aaaatcccat tttttgcaga atttgaaaga gcagctagag
    22981 aagctggtgt agcagatgcg acaagcgcac aaggagaagc cacaactaat aataccattc
    23041 ctcgataaaa gctttcatcc caactccaac ctaggaaaaa gtgggggaga aggatcatta
    23101 gaggaacagc aagcaaaatc aattttacat aattattttc gattcgttcg ataaatgaag
    23161 ctgtttgagt tggcgtattc tgcgcttctt ctactaattg gataatctta gcaaagacag
    23221 tttcggaact cgtttttgtt actcgaatcg tgatgggatt tccttgattc agcgttcctg
    23281 catacatctc atcgcctaaa tatttttcta caggcacaga ttcaccgctt aatgcagact
    23341 catcgatcgt tgcctgtgtg ctttctaaaa agccatctat cggaacagct gctcctttag
    23401 cgacaaatac caagttatcc acctttagtt gagaaacatc tacttcttgc atttgtccat
    23461 tttcttttaa taattgggct ttttgtggtt gaagattcat caaagcagta atttcttttt
    23521 gacttttatt agttgtgtat tcctctaatg caccgcttaa acaaaagatg aatgtcaaca
    23581 ttgctccttc aaagtaatta ccgatcaaac aggcaccaat agcagctaaa gccatcaata
    23641 aatccacatt cagtgtccga tcattccaca attctttcaa gccttccgat gtttgtttat
    23701 atccaccgat gataatggca ctgatataaa aaagtggggt gatggtaaga gagaatcggt
    23761 cgaagataaa accgaagatc ataaataaaa ggcagccgat tgttgctgca aaagcttttt
    23821 tctgattagt catcgttatt agacctcctt gtcaaaacaa ggatagcata ataaaaatgt
    23881 aattgataat aataacagct aaatgagaac gataatggtt atcatttggt gattaagctt
    23941 gatgttgttt ttattattta taatgattat tattaaagaa aataaaaaac cagaacattt
    24001 ctcaaataag agaagtgttc tggttttttc tacattgcaa taaaccaata accaatcaaa
    24061 atgataccaa ggataatacg ataccagcca aaagcggtaa agtcgttttt cttcaaatag
    24121 cttagtaaga atttgatagc taagacggaa accacaaaag atacgaatgt tcctacaaga
    24181 agaacaacag tttcttccat tttgaatgaa ttcccttcag ctaaatattt gacgatcttc
    24241 aagccgcttg cgccaaacat gacaggaatc cctaagaaaa atgaaaactc tgtagcgaca
    24301 aaacgcgaag caccaatcaa gatagatcct aggatcgttg cgccagaacg ggatgttccg
    24361 ggaacaagtg ccaagacttg gaataaccca acaagaagag ctgcttggta cgtaaagtca
    24421 ttcagagaag tccaacgagg tgttttgttt ttgttgcgtt tttcgacaat aataaaggca
    24481 ataccgtaaa cgatcaaaac aatggcaact ggtaagaact tgtggaaatt tgcttctaac
    24541 caatcatcca aaggcaaacc aatgatgatg gctggtatgc aagcaacgat cactttaaac
    24601 caaagtgtcc acgtatcttt tttttctacc gttgatttac ttggagaaaa tgggtttaac
    24661 ttgtgaaaat aaagaacgac gacagccaag atcgccccta attggataac gacattgaac
    24721 atcgacataa attgtgaact ggcatccagt ttgatgaatt catctgctag gatcaaatga
    24781 ccagtactac tgatgggcag ccattccgtt attccttcaa taataccgag aatcactgct
    24841 ttgataatat ttgcaaaaaa cataaattcc ttccttccca attaagatac atcttatagt
    24901 ataccgttat tttttgagaa acccaatctg ttttttaata ttaagaaaaa cttgagaaat
    24961 aaagcagata agtacacgaa gagaaaaaag aagacaaagc cctcgttcag actttgcctt
    25021 ttatgattct ctggtaaaaa ttaaaatatc cccattatag aaacgagtcg cgactatgtg
    25081 ttttcccgtt atcgatataa gacgtatcat tgatgccgtg gatagaaaat cgaccgtttg
    25141 cataagtgac ctttgttacg ctgccattta aaagcccagc acgaacaggc tgtttaggat
    25201 cgatcagatt aagcaaaaag gcgatcgtca aaccatgaga tacgactaaa acatttccac
    25261 caccattttt ttcgcagtga tgggcgatat cttcaaatcc tgtccataca cggtctcgca
    25321 atgtttcata agtttccgcc cacccagcgg tatctaagtt gtatacagca ttagcaattt
    25381 gttcaaaaga aacttctgtg gtaaacattt catcatatgt tttaaaattc aatacacgag
    25441 ggatcacacc ccacatttcc atgtcatatc caccttcaag agacccgaaa caccattctc
    25501 taatcctttt ttcaataaaa taaggaattt cttttccctt agaatgttct cctagaataa
    25561 tacgggcagt ttcgattgca cgaccactgt cactagaata agcaaatgaa aagtcgacat
    25621 tttttaaccc gcgacctaaa taatgaatgc cttcttgtcc ttgctttgtg aggggtgtat
    25681 cacaccagcc ttgtactcgt tcaattgtat tgaacatcgt ttttccgtgt cgtacgatat
    25741 aaagtgtagt ttctgtcatt ttattctcct cctaagtcgt tttaacgatt gaaaaaagga
    25801 tttgtccttt tttcctgttc aatcgtcgtt gcatcgccat gtcctggata gactgcaaat
    25861 tcatcaggta atacaaacag ctgggtccga atactatgaa gtaattgttc taaattccct
    25921 gtatacagat cggttctacc gatacttcct ctaaacaggg cgtcgccaga aacgacaaaa
    25981 tcatcaaaaa taaagctgac gcttcctata gaatgccctg gggtagggac gacgcgaaaa
    26041 gacatgtttc ctaaagtata agttttcatt tcaaattcat attctgcagg cgagacaata
    26101 acatcagcaa tatcatcatg tctaccgagt ccagaaagat tcaaaatcgg atcacctagc
    26161 catttttgct ctagtgggct gacataaact gggatttgat aatacgcgcg taaaggttcc
    26221 actgcaccga tatgatcgta gtgagtatgg gtaagcaaaa tcgctaccgg ctgttggttt
    26281 gtttttttga tttcttgttt gattcgttcc gcatcttctc cagggtcaat gatcaaaagt
    26341 gcttcttcgt tgtagaccaa ataacagttt tcttcaatca ttcctgtttt taatctttcg
    26401 atatgcatgt gcattcctcc ttgatagcca aaacttcttt catccattag tataacgcat
    26461 tcattgctag gaaacaaaaa caggtactta tttctcttta cttatctgaa ttatcagact
    26521 atatgaaaag tatttggata ttctaaagag aaggaaagta agttttcata gcattttaat
    26581 atgtccttgt tacattagat tcatccaaaa atccaaattc tatatcctat atccctgcct
    26641 aatcagcagg gtgttttttt atgtttggaa agagagctct ttttgctaaa ctaggttttt
    26701 tcaggtaatc ttagagagaa agaggtggtg gaaatgatca aacagtcaaa aatatctgtg
    26761 cggcacttag tagaatttat tttgcgacgt ggaagtatcg acaatcgtaa aaaaagtaac
    26821 catactgcat tagaaggagc gagaatccac cgcaagctcc aaaaagatgc gggagaaaac
    26881 tatgaaaaag aagtcttttt aaaaacaaca gttcaattag atgaatatta cctgatcgtt
    26941 gaaggccgtg cagacggtat tttcaaaaga gacggtattt attatataga tgaaatcaaa
    27001 acctccgaac cacgatttga agatttagaa ccagaacaag tggaactttt ctttcatcaa
    27061 gcaagggtgt atgcctatat ctatagtcaa gaacatgatt tacaagaaat aaatctgcaa
    27121 ttgacttact tccagacggc agaagaagtg atcacgagaa aggttgaaca tcagacaaga
    27181 gagcagttag aaactttttt taaaaagctg actgaagatt ataaagaatg gcttgttttt
    27241 caagaaaact ggcgcactgt acgcaatgcc tctttgatgg ctttgaaatt cccccatgat
    27301 gagtatagga aaggtcagcg tgaactagcg gtagctgctt ataaaacgat ccgtacgaaa
    27361 cagaaattgt ttgtagaagc acctaccgga acaggaaaaa caatctctac gttattcccc
    27421 gctttgaaag ctgtagggga agaagaggga gaaaagatct tttatctaac ggctaaaaca
    27481 ataactagac aagtagctga agatgctatg acagcattaa aagatacagg agctgaagta
    27541 aaaagtgtca ctttgacggc gaaagacaag atctgctttt tagatgagac gacctgtaat
    27601 ccagatcagt gcccatatgc caatggttat tacaatcgga ttaatgaagg tttatgggat
    27661 cttttgaatc atgagaatca gatcactcgt gaagtcatcg aaacttatgc aagaaagcat
    27721 acactttgtc ctttcgaact atcattagat gtcagtatct ggtgtgacgt aatcattggg
    27781 gattacaatt atttatttga tccaactgtt tatttaagac gtttttttga agatgaaaaa
    27841 aacgaggact atctgttttt gattgacgaa gcacataatt tggtgaatcg ttcccgagag
    27901 atgtattcgg cagaactatc ttatgaaaaa acgaaacgaa gtaaggaagc tataccaaag
    27961 gaattcaaaa aacttcatcg ccgtttcaac aaactattaa aagaatttga ttcgatccga
    28021 gaaatagcaa aagaagatca ttgggattat catcatcaaa aagcaccggc tgaatcttta
    28081 gtaaaggcag gttatcaatt aagcgaaaaa attaaagaat ggctggcaga atttcctgag
    28141 cacccatcac aagaacaatt gcttccttat tattttgatt tgcttcattt tttgaaggtc
    28201 agtgaatttt atgatgatca ctacgaaaca acagtcgaaa aaacgtatcg cgatctgata
    28261 gtaaaagagt tttgtattga tccaagcttg tttcttgagc agtcgttgga taaaggaaaa
    28321 agcagtattc ttttttctgc tagtttttca ccactctctt attatcagga aacactgggg
    28381 ggacaaaaaa gtctggctta caaactgccg agtcctttcc cagaaggaaa ccagcaagtt
    28441 ttcatcgcaa attacctaga gacgacttat cgaaaaaggg aacacagtct ggcaaaatta
    28501 gtagagacga ttcatgcttt tgctgatgga aaggtcggga attatttcgt tttctttcct
    28561 tcttatcaat atttagatct tgcggtggaa gcattcagac agcaatatcc cgacagcaat
    28621 gtgctaatcc aagaaacgga catgaatgag gaagaacgcg aacgattttt aacaaaattt
    28681 caaacaaatc ccgctgaaac attgattgga ttttgcgtac ttggcgggat tttttcagaa
    28741 ggaatcgatt tgagagggga ccgattgatc ggcagtatga tcgtaggtgt aggtttgccg
    28801 cagatgaatc atgagcagga actgatcaaa tcatattatg atgagaagga acaccttgga
    28861 tttgcttacg cttatcagct tcctggaatg aacaaagtct tgcaagctgg tggtcgagtg
    28921 attcgtggca tggcggatca aggaatcgtt gtattggcag atcaacgatt ttctagtttt
    28981 tcttatcgac gtttattccc acaacattgg caaacagcaa gagaagtacg aagtgttggg
    29041 gaattggaag aaggaataca gcgtttttgg ttatcaaaag aagcagtaaa tcaaaaaaac
    29101 gaggaatgac agacgtcagc ctcgtttttt gattaacgat agttagtgaa ttgcaactcg
    29161 attggtaagt caagtttacg taataaagca atcacagctt gtagatcatc acggttctta
    29221 cctgtcactc taatctgatc ttcttggatt tgtgctttta ctttcagttt ttcatttttg
    29281 atagctgtag tgattttctt cgcgttttca cgatcgattc cgttgaccaa atcggcagtt
    29341 tgtcgagctt tgccacctag agcgtgttct gattcggaaa aatggatatt tttgattggc
    29401 acatttcttt tgatcagctt accaaataat acatctttga tctgttcgat tttgaaatca
    29461 tcatcgctca atacaactag attgctgttc tctaatttga tttctactgt agaatccttg
    29521 aagtcaaagc gattggacaa ttcttttgtt gtttgctgaa tcgcattttt tacttcttct
    29581 gtattgactt ctgatacaat gtcgaagcta gcatcttttg ccataggaac cctcctgata
    29641 tacatataaa tatttaccat acatctatct tatcatagga ttagggcaga ttcttacctg
    29701 tttgctaaaa ttcttctcat ttgagttcga agtattttat tttaatagat aaactgttat
    29761 tcttacattt ggaataccaa agtaggggag aggtgcttgt gagtaaaatt atgactgcgt
    29821 atcataaaaa tgaaagatta aagaaaatag tggttatttt gataaccgga ttgaccgctg
    29881 cggtcgcttt aaattatttt ttgattccag ccaatgtctt ttctgcaggg atgaatggga
    29941 tcgctcaaat catttcctcg cttttatatg aatggtttca tatcaagata gacacaggaa
    30001 catttatttt tcttttgaat atccctgtgt ttgtattagg gtttctcaaa gtaggaaaac
    30061 gagcaacgat ccttagtttt gtgaatgttg tatgtgtatc ggtgatgacg atgctgcttc
    30121 cagtcggaca gatcactgat aatattttga tgaatgccct agtaggcggt gttttattag
    30181 gtcttggcgt aggattatct ttaaaaatgg gctttacaac tggtgggatg gatatcatct
    30241 ctcttgtact ttcacaaaca actggaaaaa cagtcggaaa ctacatgctg attctaaatg
    30301 gtatcattgt agtcatcgca ggcttcttct ttaactggga aagtgccttg tatacgatta
    30361 tttccattta tgcaatgact caagtaattg atgccatcca cacgagtcat caaaaagtaa
    30421 cagcaatgat cgttaccgtc aagccagaag aggtaacaga agaactagca aaacggatgg
    30481 tacgtggaat gacattactg ccgtctgtcg gtggctattc aaaaaaacaa gggaacatga
    30541 tcatgatggt catcacccgc tacgaaatgt atgatcttga tcagatcgtt catgaaatcg
    30601 acgacgatgc atttatcaat attttaccaa ctcattcagt atttggccgg tttgcaaatg
    30661 aaaacgaaca aaaaatgtat cgaacaactg gcgtattgcc agaaataaaa aatcgttcac
    30721 aaaaaaaatg aggaatcagg tttattttag aataaattta atctattaca tctaataaga
    30781 acatttttat aaatttaaac gagaatctta cttctaaatt ctcatttaca agcagctaaa
    30841 aaaagagtat gataaataaa aatcgtgtta aggagtgtcg tacgatgagc gaagcaaacc
    30901 aagaacggtc tggacaagaa atagaactaa tcaaagaacg tattcttgct gccttggaaa
    30961 tggtgattga tcctgaatta ggaatcgaca tcgtcaattt aggcttgatt tatgatatag
    31021 aattcaatcc tgaaaatgga gaaacagtca ttaagatgac tctaacaact atgggctgtc
    31081 cattagcaga tattttaaca gaatctatcc atgacgcatt aaaagaagtg ccagaagtaa
    31141 cgaaagcaga agtcaaacta gtctggtatc cagcatggac gacagataag atgagccgtt
    31201 atgcacggat tgcgttgggg atacgataga aatcttggct gactagctat gagaagcaaa
    31261 taggaaaaac aaaaaagcct tttatccttt ctagaagaaa agagataaaa ggtttctttg
    31321 tttataaaat tttgtctgct atattataag ttaattaaat aaatgtgttc tattgataaa
    31381 ggacattcaa atccctttcc ttttggaatc cttctttttt acatcagttt gattttcgta
    31441 tagtattctt tctcatcttc acgataaatc gcagccccat ttttttgttg tgctttaaga
    31501 ctgccaagat tttttttatt tacagacaaa agtgcctcat caatgccgat tttttttgcc
    31561 tcttgtagta ctaatgctaa tccttgtgtg gcatatcctt ttttacgata attaggggag
    31621 atgccgtaac caatatggcc agcgccgttt cttaatgttt cgttcagttt atggcgcaaa
    31681 ttaaaaattc ctacatactc atgttcatca ctttctaaaa taaagacggt tgcgggaacg
    31741 taactctcag gaagatcgat tcctaaagac gttttttcgc atttttttac ataatctaaa
    31801 aattcagcaa atgtatagcc ataagcattg ttgataaatc cactctcatt tggtccaaag
    31861 ctagtttgta gctgataagc tttctttaaa tctgcttccc atagtttgat cagtttcatc
    31921 gtattcacct ctttaagtaa ccttattcat ttgttttcta ctatagcact attgttgtaa
    31981 atagccatgc ctatttttat ttattgtgtc atatcgtatt aagaatcatc gaacaataca
    32041 aatatgaatt acaataaaaa aattatttga agttcgttca ttcgttactt atgatctcta
    32101 gaagaaagaa aacgtgaatt acttcagcgt ctagaattcc agaaggatag taatcaacag
    32161 aagaaataat caatatccaa atgaaagaag atagctgaat cgagaaaaag aggaaaaaag
    32221 aaatgaagaa aaaaataaaa tagttactaa tcccagagtc gttcgtttaa cattgaaatc
    32281 gatcatatgg ataaaacaga ttttttcacc aaccctcaat agatgatgga gttgctcgga
    32341 tgaattattt gtgtagatgg cataagggag ggcgtacaga aatgaaaaag aacaaaaata
    32401 tgttcttgac aaaaaacaca tgtaatccta aactaaaaga tgtgatgcgg ctatggcgga
    32461 attggcagac gcgctagctt caggcgctag tgagggtgac ctcgtggaag ttcgagtctt
    32521 cttagccgca taatttgttt ttttataaag agaaggtaca cctggagcga tgagaaagaa
    32581 aataacatat tatctaaaag aatataggaa aaattttaaa caacggaacc agattcaaat
    32641 aaatcaaaaa aaatttgtgt gaaggtggga cagtttaaaa cctaatagat tgattcaaat
    32701 agtagattta tagattctga tacaagaaat actggcaaac gatagttaag gaataaagac
    32761 taaacttaaa ctcaaaaaga ggtcatgcga aagaataaat cgcatgacct cttactatat
    32821 tttgaatgtg tttaaacgtt caaataatga atcttagtac caaccgtttg cttcccagaa
    32881 tgctttcgcc gcttcccaag aaccataacg tgaagtaaca tattgttctg ctactctttc
    32941 ttggtttgca gcagagtagt caccatttaa gtaagaagaa tctaattggt aacggccgat
    33001 gtaacgtccg ttcgttgctg tgtaagaacc gcttgattct ttttgtgcga tccattcttt
    33061 tgcagagctt gtacttgctg gagtagcagc agtttctgtt acagcaggag caggttgtgt
    33121 ttcagcaaca ggcgctgctt gtgtttccgt ttgaaccgtt tcttgtacaa caggttgttc
    33181 agcttgaaca ggttcagctt ggactggtgc ttcttgaacg gctgcttgag gttcagcagc
    33241 tgcttgtgca gagccttctg ttgggattgt taattgttgt cctgagta
//
LOCUS       DAIGTA010000029        32224 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.029, whole genome shotgun sequence.
ACCESSION   DAIGTA010000029 DAIGTA010000000
VERSION     DAIGTA010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.029"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(98..1228)
                     /locus_tag="NOB43_001455"
     CDS             complement(98..1228)
                     /locus_tag="NOB43_001455"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCI0982319.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="NOB43_001456"
     CDS             complement(1877..3079)
                     /locus_tag="NOB43_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0982320.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="NOB43_001457"
     CDS             complement(3139..3342)
                     /locus_tag="NOB43_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HCI0982321.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="NOB43_001458"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="NOB43_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="NOB43_001459"
     CDS             4879..5691
                     /locus_tag="NOB43_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982322.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6867)
                     /locus_tag="NOB43_001460"
     CDS             complement(6715..6867)
                     /locus_tag="NOB43_001460"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI0982323.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="NOB43_001461"
     CDS             complement(7058..7936)
                     /locus_tag="NOB43_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0982324.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="NOB43_001462"
     CDS             complement(7975..9093)
                     /locus_tag="NOB43_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HCI0982325.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="NOB43_001463"
     CDS             complement(9090..11189)
                     /locus_tag="NOB43_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HCI0982326.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="NOB43_001464"
     CDS             complement(11240..12061)
                     /locus_tag="NOB43_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0982327.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="NOB43_001465"
     CDS             complement(12058..12867)
                     /locus_tag="NOB43_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0982328.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12888..13382)
                     /locus_tag="NOB43_001466"
     CDS             complement(12888..13382)
                     /locus_tag="NOB43_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0982329.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13394..13882)
                     /locus_tag="NOB43_001467"
     CDS             complement(13394..13882)
                     /locus_tag="NOB43_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0982330.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13959..16655)
                     /locus_tag="NOB43_001468"
     CDS             complement(13959..16655)
                     /locus_tag="NOB43_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0982331.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17083..18156)
                     /locus_tag="NOB43_001469"
     CDS             complement(17083..18156)
                     /locus_tag="NOB43_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0982332.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18153..18980)
                     /locus_tag="NOB43_001470"
     CDS             complement(18153..18980)
                     /locus_tag="NOB43_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982333.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18981..19787)
                     /locus_tag="NOB43_001471"
     CDS             complement(18981..19787)
                     /locus_tag="NOB43_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982334.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19799..20884)
                     /locus_tag="NOB43_001472"
     CDS             complement(19799..20884)
                     /locus_tag="NOB43_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982335.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20901..21443)
                     /locus_tag="NOB43_001473"
     CDS             complement(20901..21443)
                     /locus_tag="NOB43_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0982336.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21701..22690
                     /locus_tag="NOB43_001474"
     CDS             21701..22690
                     /locus_tag="NOB43_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCI0982337.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22687..23424
                     /locus_tag="NOB43_001475"
     CDS             22687..23424
                     /locus_tag="NOB43_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HCI0982338.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23421..23972
                     /gene="coaC"
                     /locus_tag="NOB43_001476"
     CDS             23421..23972
                     /gene="coaC"
                     /locus_tag="NOB43_001476"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HCI0982339.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23988..24620
                     /locus_tag="NOB43_001477"
     CDS             23988..24620
                     /locus_tag="NOB43_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0982340.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24705..25352
                     /locus_tag="NOB43_001478"
     CDS             24705..25352
                     /locus_tag="NOB43_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0982341.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25357..26340
                     /locus_tag="NOB43_001479"
     CDS             25357..26340
                     /locus_tag="NOB43_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HCI0982342.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26743..28257)
                     /locus_tag="NOB43_001480"
     CDS             complement(26743..28257)
                     /locus_tag="NOB43_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HCI0982343.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28395..29201
                     /locus_tag="NOB43_001481"
     CDS             28395..29201
                     /locus_tag="NOB43_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982344.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29376..29945)
                     /locus_tag="NOB43_001482"
     CDS             complement(29376..29945)
                     /locus_tag="NOB43_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0982345.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30028..32088)
                     /locus_tag="NOB43_001483"
     CDS             complement(30028..32088)
                     /locus_tag="NOB43_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HCI0982346.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
BASE COUNT         9649 a         6750 c         5487 g        10338 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattatgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccaagacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
    12901 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
    12961 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
    13021 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
    13081 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
    13141 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
    13201 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
    13261 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
    13321 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
    13381 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
    13441 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
    13501 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
    13561 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
    13621 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
    13681 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
    13741 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
    13801 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
    13861 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
    13921 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
    13981 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
    14041 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
    14101 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
    14161 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
    14221 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
    14281 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
    14341 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
    14401 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
    14461 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
    14521 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
    14581 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
    14641 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
    14701 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
    14761 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
    14821 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
    14881 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
    14941 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
    15001 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
    15061 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
    15121 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
    15181 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
    15241 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
    15301 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
    15361 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
    15421 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
    15481 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
    15541 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
    15601 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
    15661 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
    15721 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
    15781 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
    15841 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
    15901 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
    15961 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
    16021 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
    16081 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
    16141 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
    16201 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
    16261 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
    16321 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
    16381 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
    16441 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
    16501 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
    16561 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
    16621 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
    16681 gaatatttgc ctcagatatc tgacaaaata atttatctac caatttagtt tttatctaat
    16741 atgattttta tgttttttca tagctacaaa tattgaactg gattcatata ttagttttat
    16801 taatagatta cagaagggtt aagtatattt gcatagtttc caattacttt atccttctgt
    16861 aactttttca atcttagatt tactagcccg tctcgggccc tattttacaa tggttttgtc
    16921 cacttttctc tggtagaaaa acgtggtaga aaaaataaaa taacacaaaa aaagcggcgt
    16981 ttcatccgct tttggtagaa gattggaaaa ctcagataga aaaaggacga tttttagctc
    17041 tttagaacgt tgataagtcc ccattcttac tgagttttgc cattatctcc tatacatctt
    17101 gaattctaag aataggtcat tatagatgcc taggtatttc gatcctagat ctttgtagac
    17161 ttcaagatgg gagatcgtgt catcagatgg atagaattgt tcgtccgacg aaatgtcttt
    17221 tggcaataac gcttttgctt cttcatttgg tgtagaataa ccaatatact ctgcattttg
    17281 tgccgcattt tccggttcta gcataaagtt gatgaaatca taggcacctt ctttattttt
    17341 cacggttttt ggcataacga tattatcaaa ccaaagattg gatccttctg gtgggatcac
    17401 ataatgtaaa tgttcatttt cccacatcat atcggcagct tcgccagaaa atgtcactgc
    17461 cacggaggct tcttcattga tcatatacat tttgatctca tctgccacga ttgctttgac
    17521 atttggtgtt aaatgattca atttatttgc tgcttctgtc agctgtgcca tattcttact
    17581 attcaaagaa tagcctaaac tattcaaaga aagccccata acttctcgtg caccgtcaat
    17641 cagcatcaaa ctgtctttta attccggctt ccacaaatca tcccaatgct taatttgatt
    17701 tgcatcaaag aatttatcgt tatatacgat ccctaaagtt ccccaaaaat atggaatcga
    17761 atactgatta tctggatcaa aatccaagtc taaaaatcgt ggatcaatat tatttaatcc
    17821 tttgatcttc gaatgatcta atggaagtac tagtttttct ttgatcattt tttggatcat
    17881 atattcactt ggtatagcga tgtcgtagtt tgtcccacct tgctggattt ttgtgaacat
    17941 cgcttcatta gaatcaaatg tttcataatt cactttgtat ccatattctt tttcaaattt
    18001 cgtgatcaaa ctaggatcga tataatctcc ccagttatag atggtaagta cctttgctcc
    18061 actcatgcca cttgtttttt caagttgacg aacaccaagc agcagcaccg caataatgat
    18121 gagaatacct aaaaacagag attgtaattt tttcatcgca gccgtgccac cccctcgcgt
    18181 actcttctgt ttttcttcag ccgttttgga cggttttctt tactaataaa gtagtatcca
    18241 atgaccaata tcatggagaa caagaaaact aacgcactta gcgcattgat ttctaaactg
    18301 attccttgtc ttgcacgaga atagatctct actgagagcg tcgtaaagcc atttcctgtg
    18361 acgaaaaatg taaccgcaaa atcatcaaga gaataggtaa atgccataaa atatccagct
    18421 atgattcctg gagaaagata aggcaaaatg atatttttga ctacttggaa attattagca
    18481 ccaaggtctc tagccgcatc gaccattgaa tcgttcattt cctgcaattt tggcaagacc
    18541 atcaagacga cgattggaat gctgaaagca atatgggaaa gcaatacact ctgaaaacct
    18601 aatccgaatc ctagtagtgt aaagaaaatc aagaaactag caccgataat aacatcagga
    18661 gagactaata agatgttatt catgctcaac aacgctgtcc gtgcacgtcg ttttttcgtg
    18721 taatagattc ccatagcccc aaatgtcccg atgatcgtgg cgatcaatgc agataagaaa
    18781 gccagcatga acgtattcaa tacgataatg atcaaacgtg tatcttcaaa aacagcttca
    18841 taattttccc aagtaaatcc tgtaaagctg ttcatcgttc ctccttcatt gaaggaataa
    18901 aaaatcagat agaagatcgg tgcatataag aataaaaaga cgatccctaa ataaagatac
    18961 gaccatttaa attttttcat ttatgagcga cctccttttt tcttctcgcc tgtcaggagc
    19021 atcacgatga acatagcaat gattaaaatc acaccgattg tagaacccat cccccagttt
    19081 tgtgtaacca agaaatgctg ttcgatagcc gttcctaaag tgatcacccg atttccgcca
    19141 atcagacgag tcagcatgaa taaagaaaga gaaggaataa atactgcttg gacaccactt
    19201 ttcacaccat ttaatgataa cggaaaaatc actcgtcgga aggtctcaaa gctattcgcg
    19261 cctaaatctc tactagcact gatcaaagaa ggattcatct cttccaatgc attgaaaatt
    19321 ggcataatca taaatggaat ctcgatatac gttgccacga acagaaaact gaagtctgtg
    19381 aataatatct gtttcggccc gatcccgata aaatcaaaga aatgattcac gctgccgtgc
    19441 acactgaaaa tcccaataaa tgcgtaagct ttaagcagca gattcaccca tgtaggcaaa
    19501 ataatcagca tcagccataa ttgcttgtgc ttcagttttg ttaaaaaata agcagtcggg
    19561 taactgatga tcagcgtgaa aaacgtgatc aaaaatgcat accatacaga attgatcgtc
    19621 atagaaagcg atgtccccga cgtaaaataa gatagataat tattcagcgt gaattgccca
    19681 ttcatatcaa aaaaagattg ataaatgatc attaatacag gcgcgatcac gaataaaccg
    19741 agccacaaaa tataagggac ggaatagatc ctgcgcattg ttttcattct tgtcccccct
    19801 attcttcgta gctgtcaaga cgtgcatcga attcttcttc agactcgttg aaacgcatga
    19861 catggatatc ttctggctca aaggccaatc ctactttgct tccttcttta gcttttttcg
    19921 ttgaatggac catccattca ttttgctgtt catcataaca gatgatttca taatggacac
    19981 cacgaaacag ctgagtatcg accgttacga ctagttttcc tttatctggt gtcgtgatcg
    20041 ttaaatcctc tgggcgtaaa acaacttcaa ctggttcatt tagacgcatc ccgccatcga
    20101 cacattcaaa ttgcttacca acaaactcaa ctagattatc ttcgatcatt acaccgtcca
    20161 cgatattgct ctccccaaca aaatcagcaa cgaaatgatt gattggctca tcataaatat
    20221 ctacgggtgt accactttgg acgattttcc ctttattcat gacaaaaatc tcatcactca
    20281 ttgccaacgc ttcttcttgg tcatgagtaa caaaaataaa cgtgattcct aatcgttgtt
    20341 gcagatcccg cagttcatac tgcatatctg tacgtagttt caaatcaagc gccgataacg
    20401 gttcatctaa tagcaatact ttcggttcat ttacaattgc tcgtgcaatc gctacacgct
    20461 gtctttgacc accagacatt tcactaatct cccgtttttc gtatccagga agctggacca
    20521 tacgcaaagc atcttttacc ttcttttcga tatctgattt ggacattttc ttgatcttca
    20581 atccaaaagc aacgttatca aaaacattca tatgaggaaa aagtgcataa tcttggaaga
    20641 ctgtatttac ttgtcgctta ttagctggca aatcattcaa ccgtttccct tcaaaataga
    20701 tgtccccttc tgtagcttcg gtgaatccag ctataatacg taggatcgtt gttttaccac
    20761 agccggaagg accaagcagt gtataaaatt ttccttgttc gatctcaaaa cttacttttt
    20821 ttaatactgt ttcatcatca tagcgtttca ctacttgatc aaatgaaatg attggtttcc
    20881 ccacgttttt accccctata ttacaaatat gattgcgttg caacaatcaa tacttttgtt
    20941 cgttttttga gatgattcct taattgatgt tgttttgtcg cttgataata gatcgactgt
    21001 cctgcttttg ccacatagac cgtctctcct aagcttaact ctaattcccc ttctaataca
    21061 aaaataaacg tttcagataa tgaaggttca aacgtcttat attctcctgc accttcaaaa
    21121 gtcagcaaga caggctccat ttctttttca ttcgaatcag ccacgagcca ttccaattca
    21181 tacccgtttt cttcatcgaa ataaaccgta tgatcttctt ttgaataaac cacttgcaga
    21241 ttcgctgctt cttgatgaaa aaattcttct ggagtcacac ctaagacttc aagaatagaa
    21301 aagaatgttt ccattgatgg tgaacttaaa tctcgttcca actgggaaat ataccctttt
    21361 gacaaatctg tgcgttcgcc tagttcttct tgtgtcaaat tcttttggat gcgcaaattt
    21421 cttaacttct caccaatttc cataatttcc tccgaatcga agttttctaa tagtaaactt
    21481 cctgtttact accactcgta ttagtatacg aaatttattg aaaaaggcaa ccctttgtaa
    21541 aatttttttt gctgaatatt tctttatctt ttggaataaa ttctagttgt ttgattcttt
    21601 atttttcacc taatttttgt ctaaatttac ggaagaacaa gaataaaaga gtaggcttta
    21661 tggtatgata aaagaaaatt ttaaaaggag tgtctcacga atgaacgctt ttcgatcttt
    21721 tcaggtaata aaggaacctg ttttccatac agcaatcagt gatctgccat ttactgagtt
    21781 ggctgaaaat gaagtcttgg taaaaattgc ctattctgat gtcaattata aagatgcatt
    21841 ggcaatgagc gagtctggtc aggtgatacg aacatatccg atgactccag ggattgattt
    21901 atccggaact gtcgtccaaa gtaacaatcc acgtttttca aaagaagatc ttgtacttgc
    21961 tactggtttt gggcttggcg tcacccatcc aggcggttat agccaatatc aaaaagtacc
    22021 aggagactgg ttagttcctc taccaaaaaa tatgacgctg cgtcaagcga tgatccttgg
    22081 tacagcaggg tttactgcta tgttgtgtgt gaacgcttta atccgtcaag gtatgacctc
    22141 cgataaaaaa gttgtcgtta ctggtgcttc tggcggtgta ggcagtacag cgatagccct
    22201 gttacataaa ctaggattcc agtcaatcat tgccttttcc agaaaagaag agtctgtcac
    22261 atggctaaaa agtctaggtg ctttgcaagt cgtacgacct gatgaatttc tgccagagac
    22321 aacaaaagct ttaggaaaac agcaaatcga ctatgtcatc gacacagtag gtggcgagca
    22381 gctaagcagt cttcttccat tgatctctta taacggtgca gtagctttat gtggcaatgc
    22441 tgggggaatc aaactaaacg cgactgtctt gccttttatt ctgcgaaaca tccagttgat
    22501 tggaattgat tctgtcaatg taccaataga tcaacgtctt tctttatggc aacagatggc
    22561 ggatttgcag attgcagatg aactggtcgt ccaagagatt actctggatc aattgcctga
    22621 aacagcatct aaactacttg ctggaacaca ccaaggaaga acactagtaa atgtaggtga
    22681 ccataaatga agattctaat cacagctgga ggaacgactg aaaaaatcga tcaagtacgt
    22741 gctattacaa atcattcgac aggacgatta gggcaagcat tagctgatta tttagctgcc
    22801 aatccggata ccacaatcga ttacgtgact acgaaacaag cactgaaacc gaaaagacac
    22861 tccaatataa cgatttatac gatcgaatct gcactggact tatttttaca attagaagaa
    22921 ctaacgaaaa aagaacacta cgatgcgatt atccacagta tggcagtcag tgattttact
    22981 cctgctttta gtttttcaga agaacagctg gcaaaaaacc tacccacttc ttcaacgcaa
    23041 gaagaactgg acaattggtt tgcggaaaat gaacagacag ataccactgt ttcaaagatc
    23101 tcttctaaca ccgagcatct tgtgctcgtt ttgaagaaaa caccaaaaat catttcttat
    23161 ctacgtgaat ggcagccaaa agcaaaaatc attggtttca aactattagt agatgtacca
    23221 aaggaatctc ttctggcagt cgcaaaaaat agtctgataa ataacaaaac tgattttatt
    23281 ttcgcaaatg atttgacgga aatccatggc gagacacacc acggctatct cttatctaaa
    23341 gatggaacag tggaagaagc tcaaagtaaa tctgagattg ctgcattgat tactgagaaa
    23401 attagactgg aggaatcaaa atgaaaaaga tcttactagg cgttactgga agtatttctg
    23461 cttacaaaag cgctgatctt acaagtcaat tcgtcaaatt aggtgcccag gtagatgtga
    23521 ttatgtctaa aagcagcaca cattttatca cgccattaac cttgcaatct ctgtcgaagc
    23581 gcgcagtcca tacagacgtc atgcaagaat caaatccgca ggtaatcaat catatcgaac
    23641 tagcaaaaca agctgacttg tttctcatcg cgcctgctac agcaaacatt atcggcaagc
    23701 tagcaaacgg cattgcagac gatcttcttt caacagtcgc aatggcgctt ccagtgggaa
    23761 caccaaaatt gattgcccct gccatgaaca cgaatatgta tcaaaacccg atcactcagc
    23821 gtaatctgga aacattgaga tctgtcggct atcaggaaat tgaaccaaga gaatctcttt
    23881 tagcttgtgg agattttgga aaaggtgcct tagctgatat tcagacgatc atcgaacagg
    23941 tcatgctgac tcttaatgaa agaaatgctt agaaaaaagg agtacttatg aaaaatacaa
    24001 aaaactttac attaactgcg atgtttttag ctattttgat tttattagct gttacgcctt
    24061 taggttttat ccctatcggt ccaatcaatg caacaaccat gcatattcct gtaatcattg
    24121 cttcgatcgt tttaggacca agactaggtg cttttcttgg cggtacattt ggactgatca
    24181 gcatgatccg tagcacagtt atccaaacac ctttgtcttt tgtcttttct ccgtttatcc
    24241 cagtcatcgg aacagaacat ggaagctgga aagccttgct gatcgcgttt attcctcgca
    24301 tcttgattgg ggtggttcct tatttcgttt ataaaggtct gcgcaaacta atgaaacaaa
    24361 aagcagattc cgtttcttta ttcttagctg gactttccgg ttcattgacc aatacgattt
    24421 tagtgatgaa tatgatctac tttttattcc agcaagatta tgccaaagtc atcggaacaa
    24481 atttaaatgc tgtttattca gctattctag cggttatttt tacaagtggt atacctgaag
    24541 gaatcgtcgc aggtcttgcg actgcagcag tatgcaatgt cttgttaaga tacttcaagc
    24601 acccttctct tactaactga tagtcatcgt agccgatctc tgattttttt ctcttttggt
    24661 gttactattg aatggaaaga tttgacgtcg aaaggatgat ccaaatgaaa atttttgttg
    24721 taggtgcaaa cggacaaatt ggccgacacc tgataaaaga tttagctcca agttcccatg
    24781 aaatttttgc aggggtgaga gatgttgctt cccaaacatt agtaaaaaaa gagaatgttt
    24841 cgtatgtctc ttttgattta acttggtccg tggaaaaaat gaccgaagca ttcaaaggca
    24901 tcgatgtatt gatttttgct gccggctctc aaggaaagaa tcttctgcaa gtagacttgg
    24961 atggcgcaat caaaacagtg atcgcagctg aaaatgcgca tgtctctcgc tatctgatgg
    25021 tcagtgctgt ttatgcagat gaaccagcaa aatggcctga gtccatgaca gattattata
    25081 ttactaaaca ttatgcagat gaatggctga aacgaactaa cttagatttt gtcattcttc
    25141 aaccagtcac attgactaac gatgaagaag ttacttccat tcaattaact aagcctaatg
    25201 agaaggcatc aaaaacgatc actcgctcta cagttgctgc tgtacttgcc gctctagtgg
    25261 aagaaacgga tatttctcgt acgactctag tactttctga aggtagcaaa gagttgaata
    25321 cagcattcca agaatgggca aaggaggaat agatccatgc gtgccatttc aatcaagcat
    25381 cctggttctg tagatgtatt agaacaaatt gaagtgcctg ttcctaaacc aaaacaaggc
    25441 gaattactga tcaaagtcca tacagcagct gtcaatcgaa cagatattat gaaaagagaa
    25501 tcagtctctt tgaaacctcc ctaccctatt ttgggagtcg aagtagctgg agaggtagtt
    25561 gagaataaaa gtgatatctc cacttttact cctgggacaa aagtatacgg attagtcaat
    25621 ctaggtggtt atgccgaata tgctgtgatg cctgccgatc gtgcaatcct tctccctgat
    25681 acgctagact atgtttctgc tgctggaatc tcagaagttt ttttgactgc ttatcaaaca
    25741 ctttactggc ttggaaaatt acaagaaggc gaaactgtct tgatccatgc aggagcaagt
    25801 ggtgtgggaa cagcagcgat ccaattagct agacagcttt ctcacgcgaa aatcatcgtt
    25861 actgcaggat cagaagaaaa actcgccttt tgtaaagaac ttggtgcaga tgaattgatc
    25921 aactataaaa aacaagactt tcaagaagag gtacgaaaaa tcactgaagg tcggggagtc
    25981 gatgttattt tggatttcat cggcgcttct tactgggaaa agaatttagc ttctatagcc
    26041 gttgatggac gttgggtctt gattggtatg ctaggtggga ccatcgtgcc tgagatagac
    26101 cttggtgtat tgattgggaa acgtgtccaa ctgcttggta cattattgac acctagaagt
    26161 gatcagtata aagcagagct cgcacaaact tttatgcaaa aagctgggcc ttttctagaa
    26221 aatggcaaga ttcggccaat cattgaccgt acattccaat tcagcgcagt caaacaagcg
    26281 catgaatata tggaagcaaa caaaaacatc ggaaaaatca ttttgaagat aactgaataa
    26341 aatcatgctg atcaaaaaag aggctgggac agaagcgttt aactccaaga aataagaaga
    26401 aattcacgaa aattgctttt caaatttttg tgaatttcag cttatttccg aaggaatttc
    26461 ttctgcttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt
    26521 cccacgctct ttttccgaat aaacggtgtt caaaagcttg catctgcggt aataagtcca
    26581 accaagttaa aaacataaga agctgttttt acttggctgt tcttattact tgatgcaggg
    26641 cagctttttc acaacctctt cactaaacag tgttcaatca gctgaccctc ggtattagct
    26701 caaaacgctg atttcacaac ctctttttat ttacgttcta tttcattcat tttccgaagc
    26761 aaatcgagct gcttgtatgc ccgcttgtcg cccaaaaata atgatctccg caactgaatt
    26821 tccaccgatc cggttgtttc catgtaagcc acctgtgact tcaccagcag catataaccc
    26881 cctaattggc tggttttctt tatctaatac ttcagtgttc gtattgattt tcacaccgcc
    26941 catcgtgtaa tggattcctg gtgcgatttt gatcgcataa taattcggag acgataagtc
    27001 atgttccatg gctgtggcac ggttgaattg agcatctttt ttctccgcaa catccgtatt
    27061 ccatccatca actgtttttg ctagtgtttc ttttggtaaa tcgatttttt ctgctaattc
    27121 ttccattgtc tttccagttg tgacatatcc tttttggtca taaaattcaa tagctgtggc
    27181 acgatcacgc acgccttggt caaaaatcaa ataagctgat ttttcaggca atgctgtaat
    27241 tgctgcagat actttatccc ttgtatccat ttcattgaca aatcttttcc cctcttgatc
    27301 gaccaagatt gctccttctc cgcgaacaac ctcaccaatc aagaccccct catcctgctg
    27361 cacagttgga tgaatttgta ttttatccat atcaacggtt tgtccaccta atttttcaat
    27421 catggtgata ccatctccag ttgatccttc ttgatttgtc gtaatataat cagctaaatc
    27481 gggacgatat ttttcaataa attctttgct ggcaccaaaa ccgcctgtgg taactacgat
    27541 tgcttttccg gtgacctctt ttggttcttc tccttgaaca tgtacagtca cttcattgac
    27601 cgtttcccca tttttcttaa tgtctgtcac atctgcgttg acaaaaatag ggatttcccg
    27661 ctcatggacg ttattcaata acccctccac taagtatcca ccaatagccg agccatcaga
    27721 cggacgatgt gtcctctttt cactcatccc tccagtgatc gttaagttgt ccagtttgat
    27781 accgttttga tctagccaat cgaccgcatc agcagagtga tcgacaaagt atcgaagcat
    27841 ttctttatca ttcgttcctc caccaccttt tagcgtttct tcatagaagg catcattcga
    27901 gtctttgatt ccttcttctt tttgaaattt tgtttctgaa gcattcatac cgcttgatga
    27961 tttagatgtg tttcctccgg caacaggcat cttttccaaa attactggat tcaacccagc
    28021 atcttttgct tcgatagctg ctgccatccc tgcaccacca gctccaataa tcacgacatc
    28081 ataagattct ttcatttctt ttggatctgt atatacttgt tcagaagcgc ctgatgatac
    28141 ttcggcagat tccttcgtac tagaacttgt ctgcgctgta tttttctgat ctgcgccgca
    28201 tgcgctcata gcaagaagtg caacggctgt taataaacca gcaactaatt ttttcatttg
    28261 tatccccctt ttctccttat actatattaa gtgatttttt tcacaatatc aactctgttt
    28321 ttctttaagt catatagctt tggtaaacac acgcttctta gtataattaa ggatatacat
    28381 gaaggagtta ttttatgaat catttgaaaa ccttttttac gaacagtaca aaaactgcag
    28441 gtagaatcac aaacggaatc tatattttat tacgtatcat cgtcgttatt atgctagtgg
    28501 atcaggtctg gaaccaacac tggggaaata caatgctttt attactgaca ttaattttat
    28561 ttgaaatccc ttattttctg gaaaagatat taaagataca gattccaaat atgctagaaa
    28621 tcattttgtt atcttttatt tttagttcaa cagttttagg agagttaagt gatttttatg
    28681 gctatttttc aatgtgggat acttttctac atgcattcag cggattttta gctgggggtg
    28741 tcggcttttc ccttgtttat ttgctcaata aaaatacaaa aaccatgaac ttgactcctt
    28801 tattactagc agttgtttcc ttctgttttt cgatgacagt tggtgttatg tgggagtttg
    28861 tggaattttc agcagataaa ttactgcaat tcgatatgca aaaagatacg atcatccagc
    28921 aaatcaatag tgtggagtta agtaaagacg gaaacactgt ctatcatgtt ccagatatca
    28981 ctcggacaat cattgaaagt caaaatgcag atggtaaaac agataaaaca atcatccaaa
    29041 atggttactt agacgtggga atcatggata ctatgaagga tttatttgtt aattttattg
    29101 gagcagttgt tttcagtgta tttggttacc tctatagtcg aaacgattac caaaaattta
    29161 cgttcatcaa gaattttatt cctaaaaaaa tcaaacgata aaacatgcta aaaaacaaga
    29221 gaaggggcag tgacaatact tttgtcactg ccccttcttt tttgaatgta tggcatgcca
    29281 ttagttatcc gatagtatta actcaaaaaa gtaagatatg aggaatgact atttcgtttt
    29341 ttatcccaat actgaggact tatttcacca tttcgttatt tatctaattt acttaaaacc
    29401 tgcataactt tttcataatc tggattaggt gtgccgtcta gattttcagc aataaaagta
    29461 aaacccattt ttttataaag agcaatcgcc tgatggctcc atgtctgtgt gtgaagatag
    29521 attggtccgt ccgtatggag ggtaggaaat tcttgcaaga ctctggcagt caatgctttt
    29581 gcgagccctt ttccttggta atctggtttc actgctaacc aatgaaaaac cggatacact
    29641 tgctctcttg atttttttcg ccaagcggta caggttgcta ctttttctcc tttttttgtc
    29701 tctacaaaaa acatccttct ttcaagttct tcaggataag gagcaaagtt ttgttgaaaa
    29761 tactcaagtg cttcatctgt cgtttgaaat tccccaacgg aagtctcaat ctccgcccaa
    29821 gcagattcat cttctttttg ataaaatcga aattcaaaac cttccgctaa aggcgtgatt
    29881 ggaacatttt gttgaagtgg tcttgtcatc cagatttctg cgtaaggtaa cgttttatct
    29941 aacatttttc tatccctcct cgtctccatt atgccaaata acatatgact cagctactta
    30001 tttgactata acagatagag atataaatca gaaccagtca tctgcgtcaa attcatttcg
    30061 attagcgtat acccatgttc ctgccatacc tcgcatgaaa tctcctaaag cagaagaagg
    30121 aatacctcca ccaggtgcgg gtgttcccgg actaggaagt ggtacttgcg gctgcagatg
    30181 ctcatcggtg gaatcaatag ttgacaagcg ttttttcttc gtttccttct ggtcatctga
    30241 ttccttctga tcttccgact gtttagcaac aaattctttt tctgattgtt gttttatttt
    30301 aggctctaaa atttcatttt ccaatccaga aacttgtggg gccaaatgag cttcttgcct
    30361 tatcgtttta ttagattctg agatttttct agatattctt gctaactcta ggcttcttgt
    30421 ttgttttact ttccctgttg gagaaactgc atgagccatt tgttgttttt tttctgacaa
    30481 gctttcttct tgtctttttt gttctttttg atctatctgt ttgtttaatg gtaaaacatg
    30541 taatagtgac tgagcatgga gttcttggag tgaatacggg tcatgataac tatacataat
    30601 cgtaaaatca cctgtttgtt tggtcaaata accatcctcc aatggtactt cattgattgt
    30661 aaccgataca tcctttaacg gtacgggttt acctaaggaa tttgttgctg attggatcaa
    30721 ctcttctttg tttatttttt cgtttggatg aacaataaga tcatgacctt ctaatgaacg
    30781 attgtctggt atataaacat aagtaaaggt aatttcccct cctgattgct tcctattatt
    30841 catcagttct gagtgaagta cttcaaggat ctccgaccag tgactttttc tgtctaatcc
    30901 gtttgcttgc atccaatcag aaatagaagt gactttccca ttttgttcat aagtcgataa
    30961 atctatattt ggcactcgat cagaaaattc agcaggtagg cgcaaatcag gaatacgatt
    31021 tacactactc atatgtgttt ctgcttgaag ttctttattt gtttgactat ctataaaatg
    31081 agtgatgaca gtcgatgaag cagcagatgc ttctacataa actacagctg ttgtttctgc
    31141 cacatttgat gttttcgagt ctatataagt taatacaacg ggatattctc ccggagttgt
    31201 agtatctact gtcccgttca ttttgatttc ttctttattt cctgaagttc catcgctttt
    31261 tgttacatat tcaacaagat ctttaggggc gtaactctct cctgttctta agtgaagatc
    31321 ttttcctttg atagctgttt gatcagcacg aacatggatc acagcagatg cagtcattgt
    31381 ttttaaagca attggatcaa aataggacaa ggaaatagta gatgttcctg tattagtcgt
    31441 atccacgata ttcccattgt ttgaaattac tttggacata tctccttgtg ttccatctgc
    31501 gttcttcagc ctttctacca gatcagatat cgaaactttt gtccctgcca gaacatcgat
    31561 tttctttctt tcaaactgtg aataatcttt ttcatataca taagaaactt gtgcgcttcc
    31621 accgtccttt atatctgtca aagcatgatt caaaatatca gtgatctgtt ttaactgatc
    31681 accttttgta ggatcagtca tatcggaaaa gatagaaagc ggcacactgc ttccggtttc
    31741 cgatgtccat aatgttttgt taggaattaa ccagtagtgg tttatcgttg gaggataact
    31801 gactttatta taggaagtca atgcaggaag tagctgtttt ccatttgcat cagtgaaagt
    31861 atgagtaata gtgatagggg aatcagtggt ctcagaaaca gaggtacgta cgaccttgat
    31921 ggtttgtgtc gttgcctgaa cgggtacatg catatagaca cctacagata aactgatcag
    31981 catcgtgcgc atcataaact taacgtagtg tttttcagaa cacgaccgtt ccttatctaa
    32041 acgacaagcg tgtttattta gttgttttga acgtcttttt gaacacattt attcttagtc
    32101 ctccctactc ttgtctaaac atgaagtagt aattttcata agatgatttc attatataaa
    32161 taaaatcaaa agaagatgga ctattaggag agtatttttt ttgatttttt attgtttcaa
    32221 gaaa
//
LOCUS       DAIGTA010000030        31505 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.030, whole genome shotgun sequence.
ACCESSION   DAIGTA010000030 DAIGTA010000000
VERSION     DAIGTA010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.030"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            219..662
                     /gene="rplM"
                     /locus_tag="NOB43_001484"
     CDS             219..662
                     /gene="rplM"
                     /locus_tag="NOB43_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCI0982347.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            678..1070
                     /gene="rpsI"
                     /locus_tag="NOB43_001485"
     CDS             678..1070
                     /gene="rpsI"
                     /locus_tag="NOB43_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI0982348.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(1159..2385)
                     /locus_tag="NOB43_001486"
     CDS             complement(1159..2385)
                     /locus_tag="NOB43_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0982349.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2457..2615)
                     /locus_tag="NOB43_001487"
     CDS             complement(2457..2615)
                     /locus_tag="NOB43_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982350.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            3303..4043
                     /locus_tag="NOB43_001488"
     CDS             3303..4043
                     /locus_tag="NOB43_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0982351.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGETNYIESSKN"
     gene            complement(4135..5322)
                     /locus_tag="NOB43_001489"
     CDS             complement(4135..5322)
                     /locus_tag="NOB43_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0982352.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            5644..6486
                     /locus_tag="NOB43_001490"
     CDS             5644..6486
                     /locus_tag="NOB43_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0982353.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            6486..7433
                     /locus_tag="NOB43_001491"
     CDS             6486..7433
                     /locus_tag="NOB43_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCI0982354.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            7448..7681
                     /locus_tag="NOB43_001492"
     CDS             7448..7681
                     /locus_tag="NOB43_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HCI0982355.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            8012..8596
                     /locus_tag="NOB43_001493"
     CDS             8012..8596
                     /locus_tag="NOB43_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0982356.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            8727..9395
                     /locus_tag="NOB43_001494"
     CDS             8727..9395
                     /locus_tag="NOB43_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCI0982357.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            9406..10821
                     /locus_tag="NOB43_001495"
     CDS             9406..10821
                     /locus_tag="NOB43_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0982358.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            10839..11408
                     /locus_tag="NOB43_001496"
     CDS             10839..11408
                     /locus_tag="NOB43_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HCI0982359.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            11518..13272
                     /locus_tag="NOB43_001497"
     CDS             11518..13272
                     /locus_tag="NOB43_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982360.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            13232..14998
                     /locus_tag="NOB43_001498"
     CDS             13232..14998
                     /locus_tag="NOB43_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982361.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            15521..15790
                     /gene="rpsN"
                     /locus_tag="NOB43_001499"
     CDS             15521..15790
                     /gene="rpsN"
                     /locus_tag="NOB43_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCI0982362.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            15805..15984
                     /gene="rpmF"
                     /locus_tag="NOB43_001500"
     CDS             15805..15984
                     /gene="rpmF"
                     /locus_tag="NOB43_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCI0982363.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            16016..16393
                     /locus_tag="NOB43_001501"
     CDS             16016..16393
                     /locus_tag="NOB43_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982364.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            16414..16563
                     /gene="rpmG"
                     /locus_tag="NOB43_001502"
     CDS             16414..16563
                     /gene="rpmG"
                     /locus_tag="NOB43_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0982365.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            16587..17570
                     /locus_tag="NOB43_001503"
     CDS             16587..17570
                     /locus_tag="NOB43_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0982366.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            17600..17722
                     /locus_tag="NOB43_001504"
     CDS             17600..17722
                     /locus_tag="NOB43_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCI0982367.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            17740..19263
                     /locus_tag="NOB43_001505"
     CDS             17740..19263
                     /locus_tag="NOB43_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCI0982368.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            19287..19526
                     /locus_tag="NOB43_001506"
     CDS             19287..19526
                     /locus_tag="NOB43_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982369.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(19719..20180)
                     /locus_tag="NOB43_001507"
     CDS             complement(19719..20180)
                     /locus_tag="NOB43_001507"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0982370.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(20375..20593)
                     /locus_tag="NOB43_001508"
     CDS             complement(20375..20593)
                     /locus_tag="NOB43_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982371.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            20711..22327
                     /locus_tag="NOB43_001509"
     CDS             20711..22327
                     /locus_tag="NOB43_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCI0982372.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(22568..23908)
                     /locus_tag="NOB43_001510"
                     /pseudo
     CDS             complement(22568..23908)
                     /locus_tag="NOB43_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(24184..24339)
                     /locus_tag="NOB43_001511"
     CDS             complement(24184..24339)
                     /locus_tag="NOB43_001511"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HCI0982373.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(24635..24967)
                     /locus_tag="NOB43_001512"
     CDS             complement(24635..24967)
                     /locus_tag="NOB43_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0982374.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(25481..25672)
                     /locus_tag="NOB43_001513"
     CDS             complement(25481..25672)
                     /locus_tag="NOB43_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982375.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(25766..26152)
                     /locus_tag="NOB43_001514"
     CDS             complement(25766..26152)
                     /locus_tag="NOB43_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0982376.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            26846..28051
                     /locus_tag="NOB43_001515"
     CDS             26846..28051
                     /locus_tag="NOB43_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HCI0982377.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            28068..28502
                     /locus_tag="NOB43_001516"
     CDS             28068..28502
                     /locus_tag="NOB43_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982378.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            29119..>31505
                     /gene="esp"
                     /locus_tag="NOB43_001517"
     CDS             29119..>31505
                     /gene="esp"
                     /locus_tag="NOB43_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HCI0982379.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMEDDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVS"
BASE COUNT        10745 a         4676 c         5842 g        10242 t
ORIGIN      
        1 cagcctcttt ttgtttttca ttttgacagg aaacgaccct tttatataaa agaaagaaaa
       61 gaagtaaagt ttcatataaa tttttcaatc aagcagaaaa acgttgacat tgactagatt
      121 agcgggtaat atgttaaatg gtattgtttg ccccacaaag agccccggaa actcgaagtg
      181 tatgtcaaac atcagaactt aaattggagg aaaataacgt gcgtacaaca tatatggcca
      241 aaccaggcga agtagaacgt aaatggtatg tagtagacgc aactgatgtt ccattgggac
      301 gtctttcaac agttgttgca tctgtactac gtggtaaaaa taaaccaact ttcacacctc
      361 atttggatac tggcgatttc gtcatcgtca tcaatgcaga caaagtgaaa ttaacaggta
      421 aaaaagcgac tgacaaaatt tattaccgtc acagcaacta cccaggagga ttgaaatcaa
      481 tcactgctgg cgaattgcgt gctaaaaatt ctcgtcgttt gatcgaaact tctgtaaaag
      541 gtatgcttcc taaaaacact ttaggccgca aacaatttac aaaattgaac gtatacggtg
      601 gagcagaaca tccacatgca gcacaacaac cagaagtttt agacatcaca aacttaatct
      661 aataggaggg aatttcattg gcacaagttc aatatatcgg cacaggccgt cgtaaaaacg
      721 cagttgctcg cgtacgtcta gtaccaggaa ctggcaaaat tactgtaaat aaaaaagatg
      781 ttgaagaata cattccacat gctgacttgc gtgaagtaat caatcaacct ttcgctgtta
      841 ctgaaacaaa aggcgcatat gacgtatttg ttaacgtaaa cggcggagga tacgctggac
      901 aatcaggagc tatccgtcat ggtatcgctc gtgcattgct agaagttgat cctgacttcc
      961 gtttagctct taaacgtgct ggcttactta ctcgtgacgc acgtatggtc gaacgtaaaa
     1021 aaccaggtct caaaaaggct cgtaaagcat ctcaattctc taaacgttaa tattatttat
     1081 atatcaatgt ttcaaggcac ttttcaattg tttgaaaagt gtctttttct tgtttaagaa
     1141 cacatttaag aacacatact aatcacattt attcaatcct ctctgaaagg cttcaaaaac
     1201 agttttatct actacatctg gtgtatttac gtatattctc gttgtagaaa tatctgagtg
     1261 tgttaaagca ctagatattt gattcatatt tgctccgcct tgtctagcta tagttgcata
     1321 ggtatgacga agcttatgtg gagataaatg agccaattca ggatgtcgtc ttttaattga
     1381 attgattcga tagtttaggt aatcagcgtg aacagggcaa tttacttctc cggatggttt
     1441 agtataggta aagagatact gatctggtgt ttgattaatt tttaatctca acaattgctc
     1501 agcttgcact gatttccatt tgcttagtaa tgccattaca atttcgggta cttgaattac
     1561 ggtatccttt cgaccttttg taaatttctt tttttgatat ttatccaaag catgtttaag
     1621 gcgaaccgtt tgtttctcaa agtcgatata tttccattgc aaagcatacg tctcactttt
     1681 tctatcacca agatataggg taagcatgaa aagagtatag tcatgaagag taagcaagtg
     1741 attattcaag tcagtgttta ctgcttctat ccaagcaata agctcttctg acgataatgc
     1801 ttgattacct tcccgtatcc ttctttcttc taaagcaatt tttttaggtg cagtgataca
     1861 ttgaataatt ttggtagttc ggttaaattc aatataattt agtatttctg caatatcaaa
     1921 catagaacgg acatatcctt tgataatttt tatatttgcg tattctttcg atttttttgt
     1981 taattcatct gatattatct cagtatttga atttagatag ttcattgcat actcaccaaa
     2041 cattggaagg atgtgcaatc ggaatatatc tttagtatta ctaattgtta cgtaacttgg
     2101 agctcttttt gatctagtag tctgacctag ttcatatcta ggaagccatt ttgattcata
     2161 gaattcctta aattttattt ttccttttaa ttctagtgaa tttgcattct cctctcttaa
     2221 aactgtttca attttccttt tcattgcatt ttcggcttta atagccaatt gcctagttgg
     2281 aaatactttt tgatactttt ctgatgtaat tccagtgatt tctctgaatt tttttggata
     2341 cctcagatta gttttatatt tcccatttga aagttttgta ggcaaaattc ctcactccct
     2401 taaaaagtaa ggcagtatat ttcgctattc ttagtatatg cggcgagaag aaattttcaa
     2461 attgttttaa atgtattcat aaaatctttg atatcctcta tgtcaaagcg aactataccg
     2521 tcaattctga ttactggaaa attatatata cgaatccact tatctaaagt attattatca
     2581 attcctagaa actcacaggt ttgtttttta ttcaagtaga ctctcaattt tataaaatca
     2641 tctcctaaaa aagattagaa tttttgaatt gctttgggta agcacatagg aatttcacct
     2701 ctccccagtt tacggcgagc cttacggaag tatcattatt tgctgctatt gtcatggcat
     2761 tttgttttcc cagaacaaaa agaaatctct aagtatttgt cgctaatcag gtcatggcgt
     2821 acttgagttt ctagctcgaa tagcagggat cgttattcaa aaattgtatt taattgtcaa
     2881 tgatcaaaaa taggtttttt cctattcact attaataacg ataaacatgt ataaaaagac
     2941 acactacgaa aaaagttaaa tggagtttac tgattttcat atttgtatat ggaacagaca
     3001 tagtcttgaa taatttttat aaatgttttg atgcttatca acttattcaa cccgctatcc
     3061 actttaagta taatttttcc atacgccaat aaagtagttt taggagcatg ttctcatttg
     3121 agaacgctcc ttttttatat attttgaaag ctacttacta tacgcgtagt ttcaaatagt
     3181 tttgtcattc taatcttcag caacagaaaa aaatctaaat tataaaattt agggttgact
     3241 aaaatataat ttttgtatac catatgatcg tgataatcat tatcatttag aaggagaaag
     3301 ttatgttaga agtgaaaaag cttaatgttt gttataacga ttttttagca ttgaacgaga
     3361 tttctttaaa aatacaagaa ggtgctttaa caggtattat tggtccaaat ggtgctggaa
     3421 aatctacatt gcttaaagca atgttaaata ttatccctca tcagggagag gtctccatta
     3481 ataatgaaga tatcaataaa aaactggtga agattgcata tgtagagcaa aaagctgata
     3541 ttgattttac ttttccaata aaagtaaaag aatgtgtatc tatgggaaca tatgccggaa
     3601 tgaaagtttt tcaaagaatt aaaaatgcag aatggcaaag agtttcaaag gctttggaaa
     3661 aggtcgatat gggaaaatat tctaatcatc aaataggaga attatctgga ggacaatttc
     3721 aacgtgtact tttagcaaga tgtcttgctc aaaatgcgga tttcatattt ttagatgaac
     3781 catttgtagg gatagactta gttagtgaac gaataattat ggatacgtta aaagaattga
     3841 aacatcaggg aaaaacagtg ctaattgtgc atcatgattt aagcaaggta aagaagtatt
     3901 ttgataatat tattcttttg aatcgaaatc taattgctca cggaagtgta gaatctgtat
     3961 ttaatgaaga gaatttaaaa aaagcctatg gagatactat atttattgga gagactaact
     4021 atatagagtc aagtaaaaat tagccaaatc aaaaaatatt ttataacaga taattccgaa
     4081 aaaagggtac aacaaataag cttcttacca ttagtttttt tgaatgttca atagctaatc
     4141 agaaacaatt atataaggct cgtttttagt caaaatagca tgaatcacgt aacaaagctt
     4201 acgagaaacc gcacctaagg cagttagatg atgttttcct tcggaaactt ttttctggta
     4261 aaacgcacta aaaacaggat cacattgaga agctactaaa gccgccgaaa acaaggcttt
     4321 tcgcaaatat ggagaccctc gtttactcat aacattatgc gttgcctcat attgccctga
     4381 ttgtgtcacg gaagcgtcta tcccagcgta agcaacgagt tttttcgggt tagaaaattt
     4441 ttgaatatct ccgatctcac caagaatagt cgcaccgttt ataggaccaa ttccaggaat
     4501 tgtgagaata acagaattta aagtgtccat tatgtgcttg atttctcttt ccgtttcctt
     4561 tatttggctt tcaatgaatt ttaattgttc aatcattgaa cgtagttgga aggtgaacgc
     4621 ttcttgagca aattttactc caaaggagtt agaagctgct tgcttcaatt ggtccgcttt
     4681 ttctgccttg attcggttcc tgcttaactc agctaagtat tgggccaaag tttctgagga
     4741 aatgttttct aagtcgatcg gggcactaaa cgccagcaat aactctttag aagcttttcc
     4801 gaaaacgccc tgcttggtaa aaatcgtcgc gtattctgga aagacttgat ccaatacggc
     4861 tataattttt cttttgaagt cgctcgctgt acctactaaa taagttcggt aacgagaaag
     4921 ttgtttcaaa gaaaaaacat tttcatcgga taagaccgtt tcgacaaatg agccatagcg
     4981 cattaagtca gcaatcaaaa cagaatcaat aatatcgttt tttcgtttcc gtatttctgt
     5041 acctttacgc catccgtctg tttgaagggg attcacaacg tgaatcaaat aatctgattc
     5101 gtgaaggtat gaaaagatgg acagccaata gtgccccgtg gcttccatcc ctataacaaa
     5161 gtcactgggt gctccggaat agtcgaccat tcgctcaatt aatgactctg ctccttcagt
     5221 ggtgttagga aatgaaaaac cttttagtaa tacctttcct tcctcgttca tgatagaagc
     5281 aacgtgagtg cgtttaccga tatcaatgcc taaaaagtac atgtatatct gacctttcaa
     5341 aaaaagaatt ttggattgaa atccactcaa ctgaaaagcg tcactacctt gtacgagata
     5401 cggagtaaag taaggacttt caacatctaa ctcatacgca atccacttat cagagagagg
     5461 agccagtctc tcgagtgcgg gttcaatggc ccaagggggg aacggcttag cctctcaatc
     5521 caataaatat attatctcaa aagaaatgag ttaataccaa attaaaataa cgatggttca
     5581 tagggttatc caatcaaaac cggaaggtta aaaccctaac tctaatatac aagggggaat
     5641 aatatgcttc aaaattttat taatggtctg tatgactttc actttttaca gaatgctcta
     5701 attacatctg tagttatagg gattgtttct ggaacagtag gttgttttat tattttaaga
     5761 ggaatgtctc ttatgggtga tgctatttct catgctgttt tgccaggagt agcaatttct
     5821 tatattttag gtattaattt ttttattggt gcgattgtat ttggtctatt agcttctatc
     5881 attattactt ttataaaaag caatagtgta ataaaaggag atacagcaat tggtattact
     5941 ttcagttctt ttttagcatt aggagttatc cttataggag ttgcaaatag ctcaacggat
     6001 ttatttcata tcttatttgg aaatatttta gctgtacaag atattgataa gtggattaca
     6061 attggcgttt ctgttttagt gttggttaca gttgttctat tttttaaaga attattaatc
     6121 acttcttttg atccattaat ggcaaaagca atggggatga atgtcagttt ttatcattat
     6181 ctattaatga ttctattaac tttagtagca gtaacagcta tgcaaagtgt gggaactata
     6241 ttaattgttg caatgttaat tacaccagct gctacagcat atttatatgc aaacagctta
     6301 aaaactatga tatttatttc ggcgacagtc ggagcgtgct catcattgct aggtttgttc
     6361 attggttata gttttaacat agcagcagga tcaagtattg ttttaacagc ggcattctta
     6421 tttgtaatta gttttctaat ctcaccaaaa caaaaatttt taagaaagaa ggagagaaag
     6481 ttatgatgag aaaatggaaa gcagtactgg gaagtctggg gattttgatt gctcttttta
     6541 tattcggggc atgttcaaca aatagtaaag acaaagatac agtggcttcg aacgaaaaat
     6601 taaaggtagt agttactaat tcgattttag cagatattac tgaaaatata gcaaaagata
     6661 aaattgattt acacagtatc gtacctattg ggaaagatcc ccacgaatat gaacctttgc
     6721 ctgaagatgt tcaaaaaact tcaaaagcag atttgatttt ttataacggt gttaacttgg
     6781 aaactggagg aaatgcttgg tttacaaaat tagtaaaaaa tgcgaacaaa gaggaaaaca
     6841 aagactattt tgcagcaagt gatggcatag atgttattta cttagagggt cagagtgaga
     6901 aagggaagga agatccccat gcttggttaa atttagaaaa cggtattatt tacgctaaaa
     6961 atattgaaaa acagttagcg gaaaaagatc ctgataataa aaaattctat aaagaaaatc
     7021 tagataagta tattgaaaaa ttggattctc tagacaaaga agctaaatct aaatttgctt
     7081 caattccgaa tgataaaaaa atgattgtta caagtgaagg atgctttaaa tatttctcga
     7141 aagcgtataa tgtgccttct gcttacattt gggaaatcaa cactgaagaa gaaggaacac
     7201 cagatcaaat aaaacactta gttgaaaaat tacgcacaac aaaagttccc tccttattcg
     7261 tagaaagcag tgtggacgat agaccaatga aaacagtatc aaaagatacc aatattccta
     7321 tctattcaac gatttttact gattcaattg cagaaaaagg acaagatggt gatagttact
     7381 atgcgatgat gaaatggaac ctggataaaa ttgctgaagg cctttcgaaa taatttggag
     7441 ggtaggtatg gtacaaatta aaacgactac tatactaatt tatttactag caattcagga
     7501 attatcaaaa agaaaaaaga aattaaaaaa taatgattta gcaaaagttc taagtgttag
     7561 tccagcatct gtaagtgaga tgctggctaa acttagatat gaggactatt tagatatagg
     7621 atttcaatta actgataaag ggaaaaaatt tattgacgat tacaaaaaag gttttaagta
     7681 aaagacttta tttttaggga ggataagaaa atggctattg gagtgattat gataggactt
     7741 accctaatag ctggatataa tttttttaaa tctttctcgg attattttag aaaaggtgaa
     7801 tgatttagat gagtctatta attcttgtag gattgctttt tgtatcagtt attttgctct
     7861 ttctcattag tttagctcta aggaatgagt tcagtaatag acgttaacga ttgaaacttc
     7921 aagtcctgtg taagataata tagttaattc atcttattag gaggaagtac ccatagaaac
     7981 cagagattat attacaactc accaaaaatt aatagaaagt ggactaagcc attttgaaaa
     8041 agaaggattt cagcaaacta agataaggca actgtgcttg accgcaggcg taactacggg
     8101 tgctttttat aaacatttta cttctaagga agcgttattt gaagaaatta ttcagccgca
     8161 tattaatgcg cttattaata tgtataatga agagtttacc aaatacctct taaacttaga
     8221 aaatatagat atagagaaaa gttggagaga gaacttcaat gaattagatc catttattaa
     8281 ttatattttt gagaataaac gtatattcga tttggtttta ttccaatcag ctggaaccaa
     8341 atatcaagat attgttgaaa aaattacatc atttgtgaca aaaaagacag tctgttgtct
     8401 agataagtta aagactatcg gaatgatcaa tcaaaattta gtctttaatg aagaagaaat
     8461 ccacttctac atttactcat tctacgctac attctatgat atattgaagc atagctattc
     8521 aaaagaaaag actatgctat taaccagaag attgtatcaa ttttctgttc ctgggtggat
     8581 tgaattactg agttaattaa aaaaaagctt gcattgagaa ttgttctcag ttatgctttt
     8641 tgataagatc gcactgttat ctgaataacg gtgcattttt gtcagcttaa gataacagtg
     8701 cgatcttatt ttttggaggt gaaagagtgt caaaaatcaa tccgttaacc ttgattactt
     8761 taaatatttt ttttccggtc attatttttt taggaaaggg aaatatattt caagtggggt
     8821 gtttcattat tgctacagtt ttagtattga tgtttcgtaa aataaagaca tgtatttatt
     8881 tcatcttgat ttattcagtt ctgtttttag taatgaaaat tattgatgct atcaagatag
     8941 agttttttac tatatttttt gggacatcct tatatattgt atttcgaatg ttgccggtcg
     9001 taatgatctc atggttgttg gttagtgtct atactagcaa tgaattatta tcctctttag
     9061 aaaaaataca tttaccgaaa aaaataatgt taagtattac agtagtgatc agattctttc
     9121 cgacttatcg ttctgaaata agaatgatta aagaatcttt aaaaatgaga aacattcgct
     9181 tgtctttttt tcagcctctg caatatttgg aatttctgtt agttcccgtt cttatacgtg
     9241 caactatgat tgctgaagaa atgaccgcta atgcaataac aaaggggata gaatctcctg
     9301 tgaaaagaag ttcttactat aaaacaaaca tgagcttatt agactatatc atcctgtttt
     9361 ccgttactat ttttttctta agtattttga tttgaggtga aagaattgtt tgaatttaac
     9421 aatgtttctt tttcatataa ggatgttaag gaacaagcgc ttgttgacct taatttttca
     9481 ataaaaaaag gcagtcttac attgattact ggttcttctg ggagtgggaa atccacacta
     9541 ttaaagttaa tgaatggact tattccaaga ctttatgacg gaaaattggt tggggaaatt
     9601 ttatttgaaa ataactcgct acaatcctta acacaagaaa gtatatcaaa aaatattggc
     9661 tacgtaagtc aaaatcctag aggacaattc tttacaacaa atacaacgag tgagttagta
     9721 ttttcgatgg aaaactttgg atttacaaaa gagcatatgg ataaaagaat caatgaatta
     9781 gctgaattat tagatctttc aaatatatta gataaaaaca ttttttcgct atcaagtggt
     9841 gaacggcaga aaatttctat tggatgtagt ttatcgctaa actctaaatt aattatattg
     9901 gatgaaccgt cttcaaattt ggacttcaaa gcgactaaga aacttgctga cttactttgt
     9961 gatttaaaaa ataaaggatt tactattgtt atagctgaac atcgttttta ctatttgaaa
    10021 gaattaattg atcaagttct atttgttaaa aatagaactg taaaaactac aactattcag
    10081 ttgttaaaaa ctgaaaacaa taacgcatta aggaaatttg acatttttaa tagttcgatt
    10141 gaagttccct atatcgaaaa ggtaagtgca gatgtattaa aagttgaaga aattacttat
    10201 gaaaatattc taaaagacat aaattttgat gtcaaagttg gagatgttat tggtttggta
    10261 gggaaaaacg gtgtggggaa aacaacctta ctaagaatac tcatgaagat tattcgccct
    10321 accaaaggaa agataatcga aaataaaaaa aatttgtcat cgccgttttt agtaatgcaa
    10381 gaaatggatt accaattttt cacagaatca gtgaggagcg agttagccct ggggaatgaa
    10441 atagttagta aagatcagca agaaaaaatt ttaaaaaaaa tggaacttta taaaatgaaa
    10501 gatcaattac cgtttgattt atccggtgga gaaaaacaaa gattattggt ttctatagct
    10561 tcattgtcaa aaactaattt atttctattt gatgaaccta caagtgggtt ggattatatc
    10621 aatatggaaa ggattgctga ccttattaaa gacttaaaag aaaagggtgc agtagttata
    10681 gccactcatg atccggaatt tctttataaa acatgcaata gaattattta tttaaaaaat
    10741 ggtggaataa aaaaagatat aaaacttaga gtagaagatt caactttgat agaacagatt
    10801 tttaatgaca taacgaaata gaattgagga gaatatatat gaaaacaaaa gattatattt
    10861 ttattggttt agctacagtt atttccctag taatttactt tttttcaata atggttagta
    10921 gtattggtgg ggcgtttggt cacagcatat ccccagggat ttttggatta ttatctggaa
    10981 tcatatttgt ttatattagc tataactacc ctagaaaagg aatttttact atttacacaa
    11041 ttgttttatt gttatttttt acgttaatgg gcggggcgta cttaccttgg tttatcagtt
    11101 cgattagtat ggcgatctta gctgatatta ttctatctgt atttggatat gatcgagcaa
    11161 ttcctcaagt tgtgtcttgg gttctaatgc aactaggcag tgctgccgga cagtggattc
    11221 ccatatggtt ctttacagat cgttttcgtc aagactggat agatagagga caatctgctg
    11281 caacaatgga tgcaatgatc cactacgcgg tgggtatatg gggaattatt tcagtgttag
    11341 ttgtagcaag tttatctatg attggtgtat tgattggaag aaaagtctta aaaaaataca
    11401 aaaaatagaa cgtagtttac cttctatctg tttgtacatc tctaatttac gctattacgg
    11461 aaagcattaa cagttgtaaa cgaataagag aagaaattga atgcggggga ggaaaaaatg
    11521 aaagtataca aaaaattatt tagttatgtc cctaaaatga aatactacgg atggttagcc
    11581 actttatttt ctgatttttc tgtcgtatta acagtctatg gatattacag tatttacaaa
    11641 tttcttcagt ctctaattat tgtaggagat gaatatttag ctaagagtta tgcggttcaa
    11701 actgttgctt ggttaacttt aggagcttta ttttatattt tttctggctt attttctcat
    11761 atccttgggt ttcgcttaga gactaatttg agaaaaaagg gaattagcgg tttaacagaa
    11821 gcaagttttc gtttttttga tttaaattct tcgggatata ttcgaaagac aattgatgac
    11881 aacgcggcta aaacacatat ggcaattgct cacttgattc cagatagtgc tcaagccata
    11941 gtaacacctg ttttatcagt tgccttaggc tttttcatta actttaaaat tggattggtt
    12001 ctaatcgcca tgttagtaat tggtgtattc ttgttaaaga aaatgacaga gaatacaaat
    12061 tttattcaaa aatatcaaga atcgttagat gtgttaagct ctgaaacggt agaatatatc
    12121 cgcggaattc aagttataaa gatatttggt gctaaagtaa catcatttaa agccttgaat
    12181 aaagcaatta acgattatgc taagtttgca tataagtatt ctttgagtgg gaaaacacct
    12241 tttgttcttt ttcaatggct attttttggc atagtttgca ttttgatagt tcctataacc
    12301 ttttttataa cttctcttac cactcccaag atcttagctg ttgacttgtt gatgttgttt
    12361 tttttaagtg gaattatttt tgtttctttc atgagaataa tgtatgtaag tatgcacttg
    12421 tttgaagcaa gatatgcagt cgaaacacta gactcccttt atttagaaat gaagcaagac
    12481 caactaaaat atgggaacga gacacagatt aaaaattgtg acattgcatt tgaaaatgtc
    12541 agcttttcat acaaagaaga gtgtgtttta gaaaatttca acttagtttt agaacaaaaa
    12601 agaatttatg cattagtagg aaaatcagga agcggaaaga gtacgatagc taaactaatt
    12661 tcaggtttct acaatgtgga taagggacag attaaaattg gtggtaagcc tttaaatcac
    12721 tattcaaaag acacaattat taacacaatt gcttttgtct ttcaagatac gaaactattc
    12781 aatcagagta tttacgataa cgtttctata gcaaatcctc aagcgccagc aagtaaagta
    12841 tttgacgcgc taagattagc cggttgcgaa tcgattttag aaaaatttcc cgaaagagag
    12901 cataccttaa ttggtagtaa aggagtttat ctgtcaggag gagaaaaaca acgtatagct
    12961 attgccagag caattttaaa agatgcaaag attgttatta tggatgaagc cagtgcatct
    13021 attgatccag ataatgagta tgaactacaa aaggcttttc aatatttgat gaaagaaaaa
    13081 acagttatta tgatagctca tcgattatcc agcattaaat ctgtagatga aattcttgtc
    13141 ttgtcagaag gaaaaatagt agaacgtgga aatcataatg aattaatggc taaacatcga
    13201 gtgtataaac aattggtcac taattatgag aatgcaaatg attggaggct tgacaatgaa
    13261 aaatttttat aaaaaaaaat ttgctttaac tgatcagggc gcagaagctt taactaaagc
    13321 ttctatttct agtttttttg tatactgcat taatatggta ccagcattca ttataatgat
    13381 gctgatagac gaattagttt tagaaaatgc aaagccccgt tggctttatt ttgcagtatc
    13441 gtttgttact ttgcttttca tgtattggtt gttagatagg gagtatgaaa acttatataa
    13501 tagtacttat aaagaaagtg cgcatttaag agtgcaaatt gcagacgatt tgtcaaattt
    13561 accattatcc tatttttcaa aacataattt atcagattta tctcaaacta tcatgtctga
    13621 cgttgaaggt attgagcatg cgatgagtca tgcaatacct aaagccggcg gtatggctct
    13681 gtttttccct tttatttcag tgatgctttt ggttggtaat gtcaaaatgg gattagctgt
    13741 tattttgcca acgttattta gttttgtctt aatcttgtta tcaaagaaat cccaaacgaa
    13801 agccaatact aaatattacg atactttgag agaaaactcg gaagaatttc aagaaactat
    13861 tgaattgcag caagagatta atagctttaa tctatctaaa aaagttcaag acagactttt
    13921 caaaaaaatg gaagagagtg aaaggattca tttaaaggta gaattaagta ctttttcagt
    13981 catggcctta tcctctattt tctcatatgt tagtttagca gtagtcattc tagtaggtgt
    14041 tcacttactg ttaacgggtg aagtgactat actctacgtc gttggttact tactagccgc
    14101 aataaaaata aaggattcct tcgattctat gaaagaagca gtgcttgaaa tattttattt
    14161 agctcctaaa atacagcgaa ttagagctat gaaggaaacc agtatccaag agggatcaga
    14221 tagtcctctg aaatcttttg acattgagtt gcgagatgtc tctttctcat atgataacaa
    14281 taccccaatt ttagatcata tctcttttac ggctaaacaa ggagaagtga ctgcgttagt
    14341 aggtgctagt ggttccggga aaactagtat cttgaaatta gtgtctagac tgtatgatta
    14401 tgatgaaggc tgtattttaa ttgatgggta tgatattaaa cgtgtatctc cagcttcttt
    14461 gtttagcaaa atcgctattg tttttcaaga ggtaactttg tttaatacaa gtattttgga
    14521 aaatatacgt attggaaata gtcaagcgtc agatgaggaa gtgaaaaaag cagctcgttt
    14581 agctaactgc gaagacttta ttgaaaaact acctgacggt tatcatacat tggtcggaga
    14641 aaacggaagt tcactttctg gaggagagcg acaacgccta tccatagcac gggctttttt
    14701 gaaaaatgcg ccaattttaa ttttagatga aattactgcc agtttagatg cggaaaatga
    14761 aaaacgtatt caggaaagtt taaatcgttt aatacaagat aagacagtac taattatatc
    14821 gcatcgcttg aagtctattg aaaaggtaaa taaaattgta gtgatggatc aaggaaaact
    14881 agttgatcaa ggtactcata atgagttgta tcgaaggtca gaaatataca aaaatctcat
    14941 aaagaaaact aaactatctg agaaattcgt ctatgaaaaa gaagctcaat cacgatgatg
    15001 aaataggctt taaattaacc tacaattttt gggatatagt tataattctt tttcaaaaag
    15061 aataatttta ttaaacagca tctaattttg aatacacgaa agaatcagta tgattgaatt
    15121 agttcactta atgtctattc ttataatata aggaataatc aaagttttaa aaaattggcg
    15181 ataaaccagt taaacataaa agattgaata aaaagttata gtttctttca tattgccgtt
    15241 ttaagtagag gaaaagctac ttaaaacggt atttgtgttt gattggacta ataaaagtga
    15301 attcttattt ttcagagcct aaactgcata ttcttttaaa tgatttgatt atctctatgt
    15361 accgataaat tcgttttcaa atagttatct attcatatga gttttatttc atgttattta
    15421 ttgttgacaa gagcaactct tgttggtaaa gtatcagtgt caaaacgtaa cgattacgat
    15481 ttgaggtgtc taaatcaaaa taaaaggagt ataaaggtat atggcaaaaa agtcgaaaat
    15541 tgctaaagca aagaaacaaa tggcgatgat tgaaaagtat gcagataaac gtcaggaatt
    15601 aaaagccgca ggagatcgca ccgctctcgc taaattgcca agagattcaa atccgaatcg
    15661 tctgaggctt cgtgatcaga cggatggtcg tccaagaggg tatatgcgaa agttcggtat
    15721 gtcccgtatt aagtttagag aacttgccca tcaagggttg attcctggag taaaaaaagc
    15781 aagttggtaa aaggaggaaa tatcatggca gtaccagcaa gaaaaacatc taaggcgaag
    15841 aaacggttaa gaagaactca tcaaactgta gtaaaaccag aaatttcatt tgacgaagcg
    15901 aatggtgatt atagacgtag ccatcatgta tctttaaaag ggtactataa tggaaagaaa
    15961 gtaattaaag gagcttcaaa atagtttaat atataacttt taggagggaa tcaaaatgga
    16021 aattatttac ccacctttag ttgaagaagg attaaagtat tatcttgaaa cgacccagca
    16081 atcgctagat aaatgcactt tttatcgttc gatggtagag agaggaatta ttactgaaac
    16141 gggtttaccg acccaacagg caattgaaaa tggattagtc aaagattact atgaggacca
    16201 aggcttatca tttgatgatt ttttaagaat ctatccaatt tttgaagagt atgacgagga
    16261 gttatttcaa tgtatcgatg gttattggga gatacctgtt gatatgaaag aaaatttagt
    16321 ttcacaattg gaatctggcg agttaacttt tgaagatgca caacaaattc aagcatatct
    16381 tgaagatcga taagtattga aggaggaaga tttatgcgtc aaaatattat tttggaatgt
    16441 gtcgaaactg gagaacgtct gtatctcacc agcaaaaata aacggaataa ccctgaacgg
    16501 ttagaattaa aaaagtattc gccaaaattg cgcagacggg caatttttaa agaagtgaaa
    16561 tagctaagtg gtaaaaaggt gacaaaatgg gcataccagt tacaatcgtt tctgggtttt
    16621 taggggctgg aaaaacaacg ctaatcaatc aagccttgca agtctcaccc taccccaggg
    16681 aagaaattat tataattgaa aatgagtttg gtgaagttgg gattgatcac aaattattag
    16741 ttcatagcga ggaacgggtg ttacaactaa ataatggatg tatgtgttgc agtcttcgca
    16801 gtgatttatt agcaatattg atttctttac tggaaacaat agaagaacat caacaaccaa
    16861 tttcacaaat catcattgaa actacaggta tagcagatcc ccaaccaatc attcaaacac
    16921 ttttaacagc gcctcaacta agaggaagag tatatatcga tagtttattg actgttattg
    16981 atagtgacag ttttgaactt attgaaagag aaccacaagc ccttaagcaa cttgtcatgg
    17041 cagatcgcat ttttgtgtct agaaaacaaa acttgaattt atctgcacta aaaaaattac
    17101 agagagaaat caaaagtatt aaccctttat ccgatattcg aatgttcaca catagtgaaa
    17161 cgattcaaaa aaaggatttt tataatttga aaaaatttaa tcatccctta gtttttgaaa
    17221 gtgattcatc agaaaatcac tataatggca aatactatca tcaacaccat caagtacatg
    17281 agtttaaatc aattctctta acttcagatc aagacataaa aaaagatttt ttactccaat
    17341 ggattgactg gctgatttta accaaccaag ggagcctgta tcgttttaaa ggattgattg
    17401 ctttacaaga gcaggatttt atagttgcca tgcaagaggt aaacgaacag gttaattttc
    17461 aatacaccac tcgacaaaaa gaccaaacca ctattattct aatcggaaaa atgttggatg
    17521 aagaaaggat caaacagagt tttgataaat tactggcgga aagcaaataa tgataagtag
    17581 tgattggggg taatttctaa tggagaaaac ggatatatct agtgcatatc gacgacttaa
    17641 aagcccgaat attaaaacta gaaaaagggc attaaaaatt atcaaagaac ataaacgaaa
    17701 taaaatgaag aaattagcat aattaaggaa ggaaaaagaa tgaagaaaat cagtgtagga
    17761 cttattggga tagcagctct aggattattg ggagcttgct ccagcactaa tgatgcaaaa
    17821 gtatcgaatg ataaagatgg aaaattagaa attgtaacaa cattctatcc aatgtatgat
    17881 ttcaccaaaa acatcgtcgg cgatgaagcg aacgtggatt taatggttcc agcgggatca
    17941 gaacctcatg actatgagcc ctcagctaag gatatggcaa aagctcatga tgctgatgtt
    18001 tttgtatatc ataacgaaaa catggaatca tgggtaccaa aagctaaaga aagttggaag
    18061 aaagctgggc ctaatgtagt agaaggaaca aaagacatga ttttattgcc aggtagtgaa
    18121 gaagaagatc atgatcacgg agaagaagat caccatcatg aactagatcc tcatacgtgg
    18181 gtttcaccca aaatggcaat taaggaagtt tcaaatatca aggatcagtt agttaaattg
    18241 tatccgaaaa aagcaaaagt atttgagaca aatgctgaaa agtatttgac taaactgaaa
    18301 cggttggatg ctgactatac cactagtctt aaagaagcga aacaaaaaag ttttgtgacg
    18361 caacacgcag cctttggata tttagctttg gattatggat tgaaacaagt tcctattgct
    18421 ggactaagtc ctgaagaaga gccatcttct ggtcgattag ctgaattaaa agagtatgtt
    18481 aaaaaaaata agatcaatta tatttacttt gaaaagaatg ctaatgataa aattgcaaaa
    18541 actttggcca acgaagctgg gataaaattg gaagtactga atcctcttga aagtcttaca
    18601 aaagaacaaa tggataatgg tgaagattat gtttcagtaa tggaagacaa tctaaaagcg
    18661 ttagaaaaaa caactatggt tgctggtgaa gaggtagttc cagaaaaaga agcgaaggat
    18721 gaaaagacag ttgctaatgg gtactttaaa gatgccgatg tgaaggatcg cgaattgagt
    18781 gattatacag gcgaatggca atctgtttat ccgttgttaa aagatggaat tttggatgaa
    18841 gttttcgatt acaaagcaaa aatcaataaa gacatgacag ctgccgagta caaagattat
    18901 tatactactg gctataagac agatattgat actatcaaca ttaaagacaa caccattgat
    18961 tttgtagtca acggtgaaca tcatcaatac acatacaaat atgttggata caaaattttg
    19021 aattatgaaa aaggaaaccg tggtgttcgt tttaattttg aaactgatga tgcaggtgct
    19081 ggtcgtttta aatatattca atttagtgat catggaattg caccaagtaa ggcagagcat
    19141 ttccatattt tctttggtgg agaaagtcaa gaaaaactct ataatgaatt gcataattgg
    19201 cctactttct atccagcttc attgtctaaa catgaaattg ctcaagaaat gatggctcat
    19261 taaaattcaa tttttggagg aaatacatgg taagaaaagt attattgtct atggattcca
    19321 agaatattga tgcttatcgg cgttatcgat ttgcaaagca aatgagatta aatgggagta
    19381 cattagctga tattgctgca actttacatg ttagtattga cacagttcat agagtattaa
    19441 aacgggatcc tgattgttgt tttatcaagg tcaatactgg aagaagtaga cgtttagcaa
    19501 aacggcataa tagcttggcc aattaattga taataccaga gtagatcatt tttcccttat
    19561 ttggatttga tctgcttttt attatgtctt gaattgtcaa atcaagcgca acactttatc
    19621 aaagaagact tcataaggtg ttctccaatc taaacacttt ctaggtctgt tattcagttt
    19681 ttcaatcatc tgatttatcg ttgagttatc taccgtagct atctctttcg attttggcaa
    19741 gtattctcga atgagtctat tcgtatttta atttgttcat tgttgccaag ggcatgagga
    19801 tctggaaaat aaaagggcat attattcaat gcttctgtaa ctgcgaaatg attggagaat
    19861 tcttttcctc tatctggagt gatcgttttg accgcctcat ttggaatact gcttaaaagt
    19921 tcaatcattt tctcgctcac ataagcggct ttctttctgg ggaccttctt tcctgctaaa
    19981 aggaagcatg attttctgtc tgtcaaagtc actaaacaag taccaccagt tttgccagct
    20041 acaatatcgg ctttccaatg accaaaatca cttctatcat ctgcggattt tggacggcca
    20101 tggatcgaat gagtaaggca aatctttcca cgagactcga catgattttt tgtatgtctt
    20161 gtttttcctc gatggtgcaa tgaacggatc aggcctttat tgccgtgtga gaggggttct
    20221 gtatcgaaaa gatcattgca aattgcacgt tagatcgtga taaaactaat tgaaaagtcc
    20281 atatgttcat gcttcaaacg attcgagatt tcctctggcg accactgaaa atcgacaaat
    20341 aaatgacgaa caattgacca aactcacgga tcatttagaa tgtgataacg tccgcatttt
    20401 tttcttcgat aagcataatt tttttccgct ttggaaggtg aatagttttt ttcttgtttc
    20461 ttctcagttc atgtaaaata gtaaacgggc tatgctgaat gtcgttgcca attatactaa
    20521 tagaaaatcc ttcttcgtga agcagaaaga ttctttctcg ttcgagtata gtaagatgac
    20581 gatactggct cataattatt ttccttctag gagtgttctc gacaaactta tactagttgg
    20641 atatcgatta tgactcattt ttatgtgttg cacttaaagt gtaaattcaa ggtatagaaa
    20701 gaggttccct atgaaaaaaa tacctattac aatcttaact ggctatcttg gttcaggaaa
    20761 aacgatactt ctaaatcata ttctgtacgg tgatcacgga aaggaaattg ctgtcattgt
    20821 aaatgacata ggggaagtaa atgttgatgg ggtattagtc gacaagaaag gttttaaaag
    20881 aactggagaa aaacttgttt cgatgccgaa tggatgcatt tgttgtacat tacgcgaaga
    20941 tttgattgtt gaactagatc aattagtgca attttctgac ttgaatcaaa ttgttattga
    21001 agcttcagga atcagcaaac caattccaat tattcaagca attatattag ctaaaaaccc
    21061 tttagacatt gatttgaccc aacgattaga gattggtgcc attattatag tagtggatgt
    21121 aaaacgtttt tgggataatt tcgaaacggg tgaaaagatt caggaaagaa aagctgaagg
    21181 taatgtagtt gaagaagaac aggatattcg tggcttgtta attgatcaat tcgagtgttg
    21241 taacatatta cttttaaata atagtgactt agtgtcaacc aagacgattt acaaaattaa
    21301 cggtctaatt gctaagttac agtccaatgc caaaataatt aggacaatta aaggtgaagt
    21361 agacttatcg aaaattctaa atacaaatct ttttaatata gatgagactt cctattcagt
    21421 gggctggttc aaagagttag agcttggcta tcaaaatcat attcctgaaa cagaagaata
    21481 tggtatctca agttttatct atcgaaatcg gttactcctt gacgcacaaa aatttgccca
    21541 tcttacggat aaaaattttc ctggcaatat tacaagagca aaagggtttc tttggtttgc
    21601 ccaacatagt gatttttcga cgatctttga aacatcgggt agctataaaa gtattgaatc
    21661 attaaattat tgggtagcta gtttacctaa aattgagtgt caaatgatta tacaaaaaaa
    21721 tcccgaattg aaggaagcct ggcatccgtt gtttggtgaa cgcattaata aactagtttt
    21781 tattggtatg aagatggatc aacaatgtat taaggaacaa cttgagggtt gtttaactga
    21841 ttctcttaat gcagataatt tccgaaaaat ttcaccattt ccatggaaaa agtctaatat
    21901 gtttagccag atatcgttaa tgaaattttt aagaaaagct ggtgtcaaga taggcgatgt
    21961 cataattatt ggcattttga ttattacctc ttttattccc ttatttgtat tctctataga
    22021 aaaggagaat gaaacaactg aagatgctat caaatatgcc atcgttcgaa ttgatggcaa
    22081 ggaaatggat cgcttcgatt tggataagat caatcataaa ctcgtgaatt atcatcctgc
    22141 gaagggacaa tataatattg ttgagattaa agatggaaga attcgagtta aagaagataa
    22201 tagtcctgat caaatcgcgg ttagaactgg atggatctca aaacccggtc aaacgagtat
    22261 ttgtttaccc cataagttag ttattagtat tgagaaaaaa gaaagcacag attactacat
    22321 ttactaatct ggaaatagat gaggaggttt ttaataagaa aaagatatta ttattaataa
    22381 tagcaggggc tttattaagt gtgttaagcg cttgtggaca agaaaaagaa gcggtgacaa
    22441 caggcacaag tatctttaac gggacctgca atggtttagt taacagtcgg ttagattact
    22501 tattttggct cttcgtcaat gagtgttggt gaagaaattc aatagaataa tcgagatact
    22561 cacacggcta gacagctatc ttgtctagcc gtgttgttgt tctggcttta gtcagttggg
    22621 tagtattctt agttttctta aaatattttc ctcgatataa aaagattcgt tctcggtagt
    22681 tttgaaagtt tctatagcca taggcaattc gttttagtac tttgatatgg ttattcaaac
    22741 attctatagg gccgttggaa tagggaacgc gcaacgctcg tttgatttct gtttggtatt
    22801 tcttgaaggt cgtgaacact ggttggtagt gctctggcaa ctccttgtag tcttctttta
    22861 ggagcgcgac gaattcagga acatcttgtc ttctgataac ggaaagaaaa tcctggtaga
    22921 cttcgtagcc tcgctttaag gaatcatcat aagataatag ccgatcgact atctctgctt
    22981 ctgtcagatg atctcgaaat gacggacgcc agtagcgatg ctgacctttc aattcccacg
    23041 cattcttttg aagtagtttc cagtatttct ttaagtgctt cgaccgacga tccccttttt
    23101 taaaggtctt cattacttga attcggtggt tggtaaaagc ccgaccaatg tgttggctaa
    23161 tatgaaagcg atcggcgacg attcgggcat tcggaaaaca ctctttcacc aatgtgcgat
    23221 agggtgtata gaaatctgaa accactagac gcacttgttc acggactttt atagggtagc
    23281 gcaagaaata gtcgcgtaaa ggattgagtt gccgattttc cacaatatca atcagttgat
    23341 gggtcttgcc gtccatcatg acaaagctca tggctcccga gacatttttc actgatttga
    23401 attcatcgaa acacaccact tctggtaaca gctggctcaa agaaatggtt ttaggccgaa
    23461 ggctgcgaag tattcgaatg acagtggtcg gagaaatgtg cttcatacgt gcgatcaaag
    23521 acatagaaag aggttcgctt aatagctcaa gaatggcttg tttgactctg cgagcaatgg
    23581 agcagcgacg atcactaact gaatcttctg ctaaaaaagt ctttccacag tgtttacatt
    23641 tgaagcgctg tttgttaatc cgcagaatgg tcttgtagtt actgacatca ttcaataaga
    23701 tggatacttt tttccagccc tatttaatga tcgtttgttc attttgatag tggcgatgaa
    23761 agcattcctc cggttgatag gtcaatgtgc catcaaaaac aaaacatgtt tcgtcattga
    23821 ttcgctcttt gcgaaaggca tcttcatgaa agataagatt taggtctaga atatctagta
    23881 actctttggt aaactctgaa taggacatct tgaaacactc ctttgaatgg ttttcgtcga
    23941 ctttattcta aaggatttta aggtgtctgt ttgcgtttat tagaaaaaag aaaaagtatt
    24001 ggcaacagaa ggcgtcacca acactagata ttatagatcc cttattttct tcgcttcaaa
    24061 ttgtcaagga gtcatcataa attttgtatg gattcttttg tttgggtagt agtcttctaa
    24121 ataatcttgg attaacacct tcatctctat tttactttta tatttgttgg agtcgattaa
    24181 ttctcatttg attgatcgat gaaacgcttc aattactgca ttgtcaacag gagtcccagt
    24241 ttggctcact gaatgtgtga tgtggtggtc gttcaacagc tcttgataaa taaaagaccg
    24301 atgctggcta cctctatcgg aatgaattac cgtaggcaat tctccttaat aaatttgtaa
    24361 tggacggacg acaatctctt ttttcatgtg tgaatctacc atatagtaac gtagaatacg
    24421 agttgctaag tcaatatagg tggacaaata gaggcgaccg tcattacatg gaatgtaagt
    24481 aatatccatc acccaaacag catcaatttg gttctgttca aattatcgat tcaacatttt
    24541 tttaccattt ctttgattgt tttttctcta ccatgagaag atttgcgtcg atgaaatcct
    24601 cttgtgcata aattcatttc acgcataaga acagctacaa cacgtttatt gatttcgatt
    24661 ccttcatcgt aaagtttttg agtgatccct ggagatccgt atcgatcttt gtgttcgtag
    24721 aacactcgtc ttcctctttt agtcgtttat tttcctgttc aagaatgtag aaatctgctt
    24781 tatcaggtaa tctttttcct tgtccagcaa aagcattttt cccgtatcga cgatattctg
    24841 aaacccatcg ggaaattgtt ggacgagaga tattgtattc ttcagcaatt ttcttggtag
    24901 ttactttttt ctcaaggata tcctgtgaaa tctttagttt aaatttacga tcatatgttt
    24961 ttctcaatag agttcattcc ttccggtaac gtaactgata gtcaagaaaa gtgtatcata
    25021 gcccaactta gtatcagggt ttgtcaacta aactgtggaa gttgatagat aagagttttt
    25081 aacaaccaaa attctcttga ctatttttga aatcagacaa attttgattg gacacatagt
    25141 tgaataaatc taccgtcgtt acggaaggta aatcgcatgc ttttcaattc tagaggagaa
    25201 gtcctcgttg aagtaccata gcccagttct ggattcgacc tcctgcccac ttcatacgta
    25261 aataaagtaa ttttaggagt gagactgtga caaaagttat ttttaagcta aaaacgaatt
    25321 aaaaaacgtt gataattaaa atcattcgtt ttagattcta tgaatcatta tagaacgctg
    25381 taaaatcgat actttataat tataaagaag atagtttcaa atttattgtt cgaaatttga
    25441 aactatcttt ttacttatgt cacagactcc cttagttgag ttattcttta atttcgaatt
    25501 tcgagatagc tagatatatt gcaagcatac attcttgata acaatcttga tcatattttc
    25561 cagttctcca ggattgctta tgaatcaaag agctaaatct tttgagaatt gcctcaacag
    25621 cttcttcatt tccagccttt gctaaaatga aatcttcttt taaagaattc ataaatctac
    25681 cttcttccca tggacttata atctatttct ttgggaagga ggagaacgag caaagaagca
    25741 tacaaaatta gttattatgc agatattaaa ccagcatttt ttgaattttt ttgtaaagtc
    25801 gatgttttaa atttgtcgca ccctgtcttg taatccccag aacctttcca atttctttat
    25861 cagttttatc aaagataaat ttttcgataa gaaaaatttg ttcaggttct ttcaacaaag
    25921 gaaggatttt tgctaatttt atatcttcaa caaggagagt cacatttaaa acattaatcg
    25981 gttgtttaaa ttttatagta tctttagtaa acaaatatgg tgggagttga tcaagttgtt
    26041 catgtttttg aatttcttct tgttttttat aataagtatt agcggtgttc aaaatgacct
    26101 tttcaaagaa tcgaatcaac tgggcattta cgcgttcgtc gttatctgac atattgcaca
    26161 cctcctccat taagatttaa agggaaaaga ggcaaaaaac acgaaaagaa gctaatgcaa
    26221 ttatgctgcg ctgcgaataa cttctataag ctcacatgca ttgataggac tgctgatgtt
    26281 tattttcaaa aatgtttttt tagttgataa tggatagtta tctttatact tagaaaagaa
    26341 aattcatata tcttcttaaa tatcaaacat gtccttatgg ctaagaaaat gtcttgagct
    26401 ttttacgtat aataaatctt ttctaaaacc tccttttgga taatattctt attcgtgtat
    26461 agattgtatt ttttatttct tcccccttca taattaacaa ctagaaaaga gttcgaatag
    26521 acacgtattt gaacgaaaat ttttattgga ttcccaaatt ggaatattta gaaacgaaaa
    26581 attcctatta tctgtatagt gcttagataa taacggatca taataattat tgtctttgaa
    26641 ctagatatat gtaaatagta ttcatcatga tgaaaaatga tgagttctcg gtgataaaat
    26701 gtacttttta cggtggaata tacatgaaag cgataagtgg atattttata atgaagtaag
    26761 ttagcttatt ttgacagagg aatagtattt tagataacgt ataaaatact atttaatgat
    26821 gtagaaagga aagagagaaa caaaagtgtt ttcagataaa gaagtcttat taaagtctct
    26881 tcatgtttgt ttaaagttac ctatcgtggt ttttaattcc gaattcagta ttataaaaga
    26941 gtatcgctca gatagaacta cttatttttt ttatgattat aaaaagttac taactgataa
    27001 tattaaaaaa actaaagatt tccatttctt tactggtgat tttaatgaga tgtttcttct
    27061 atacatgttt aaaaccagat attacttatt tggtccattt agagcaaata atattgataa
    27121 agtttttttt aaactaaaaa tgaacaattt gaatgttgca atggctgata gagaacgact
    27181 ctataattca ttgcaaaatt tgactttgta ttctttagga gacattcgag atattctgat
    27241 tttagttcat tattttttta ctggaaaaat agaagatcta ttccatgaac cgttaattga
    27301 atatacagaa aatctaagta aaactatcga gcaaatcaaa atagataatc tgttatcaca
    27361 aaattacgat ccagaaatat atctgtttct ttatgaaaat aaaatactgg aatatgttaa
    27421 aaatggagat attcgaaatt tagaaaacat ggtttttaat ctgagtaatg gaataattcc
    27481 aagtgttagt ggagatacga ttcggtctga aaaaaattat tctatcattg tttttgaaaa
    27541 gttagcacaa acgtctataa cattaggaat ggatataata gaagcgtatc aaagtagaga
    27601 tgctttgata caagaaaacg aattagctgt atcgttacct gaggtcttaa aagtgaggga
    27661 ttctgggatt gtttattata ctaaggaaat cggaaaaact aagatagagc atctttctcc
    27721 cttaatttct tctgtcgttc aattcatcgg cttaaatatc tataaaagaa ttactgtaaa
    27781 ggaaatagct aattattttt ctgtaagtga aactaaatta agagaaagct ttaagaatga
    27841 aatgcatatt acgatttata attatatctc taagcgaaaa atttctacgg ctaaaataat
    27901 gttgaaatca aaccatacta tcagtgaagt ttctttaggt ttaggatttt cagattcttc
    27961 acacttttcg agagtattca aaaagtacgc aggtgtatct cctaagcaat atcaattagg
    28021 tttagtggac aatttcaaca acattagctg agaggtttta ttttattatg agactatatc
    28081 atttacgtag tttggaggag ttgaggaaat tggattttaa caaaaaattt ttttgggaaa
    28141 tttctgattt gagttgtttc gtagaatctg agcgtctaag taatggtaat aatagtgtgt
    28201 taaatgaata tgacaaagta gtaattaata aagtaaaaag tttatgtgaa gaagctagag
    28261 aatctatcag tcatattaat ggtagcaatt ttaaacaaac attatttaat ctgattaagc
    28321 tagatgctaa aatatcaagt tatttattct ttttgataca tgatgaattt atggattatc
    28381 aaaaattgga tcagttaatt gaaagagaaa gctgggaaga ttattacgtg ggtctaactt
    28441 tttcagaaaa gttaaacaac tacaagttaa tagattataa gtatttgagt gaaagcaatt
    28501 aattattcat gtagagtact agacacttta aatatggaca attcaattat aaagaaaaag
    28561 aatcaataat ttaatgaggc tgtgacaaat gtcatttttt gtttcgctaa aaacgagtga
    28621 aaaaatgttg ataactccaa tcattcgttt aagattctag gaatcattca gaaatgctgt
    28681 gaaaccgata ctttataatt ataaagaagg tgatttcaaa ttccgaagaa ggaatttgaa
    28741 gtcacctttt tacttatgtc acagtctcat tcagtaatgc gggataaggc tccttattcc
    28801 gttatttgaa tactctgaag tttaatctaa gaaagggtaa tattttgaaa acatgcttca
    28861 tcgcatagaa atgaacttaa tttcagaaag aatacataca tatcttttta tatgttttca
    28921 gctgctgaat ggttaaaaag cacaaatatc cgaaaaaaac atgaagaaat gtactttttt
    28981 tgttgtaatg ttcatgaaat tctctaagta aattagttaa cataaggtta gtaagattcc
    29041 tattctgtga ataatacgta tcagatttat cttttattct tactaggaaa gtaattatta
    29101 agggagttga tttgaataat ggttagcaag aataataaga gagtatttct agaaaaaaca
    29161 aagaaacgag tattgaagta cagtatcaaa aaattaagtg ttggggttgc atctgttttg
    29221 attggtgttg gtcttgtctt gggaacaact gaactagtta aagcacaaga tgaaatttct
    29281 ccaagcagcc cacttgaaac agcgataagc tccgtacaag taggtgacaa agtagcttcg
    29341 gggaatactt ttcaggagaa tcctggttat acgaaaaatt ataacttttc ggatttacaa
    29401 tttagtcctc aagaactaac tggagacaca ctaaaaggca atacaattgg atttgaagtt
    29461 tacggaaaac ataatattgc agcatcaact aaaaactggg aaatccgtct tcaattagat
    29521 gaacgattag ctaaatatgt agaaaaaatt caggtcgatc caaagaaagg aattggatct
    29581 tctagacgga cctttgtaag aattaatgat tcgctgggta gacctacaaa tatttggaag
    29641 gtcaattata ttcgtgcaag tgatggatta tttgctgggg cagaaacaac cgatacgcaa
    29701 accgctccta atggggtaat tacgtttgaa aagagcctag atgaaatttt taaagagata
    29761 ggcatagaca atctcaagac cgatcgttta atgtatcgaa tctacttggt aagtcatcaa
    29821 gacgatgata aaattgtacc gggtattgat agtacgggct actttttaac agattcagat
    29881 gatttctata atagcttaga tgtatctgaa aataatcctg accagtttaa acatggatca
    29941 gtaagtgcaa aatatgagaa acctaatact caaacaaaag atggttcagg atccacaggt
    30001 gctaatggag ctataatctt agatcataag ttaacgaaaa attataattt ctcatattca
    30061 tcttccgcaa agggcacgcc ttggtatgct aattacaaaa ttgatgaacg attagttcca
    30121 tatgtagcgg gtatacagat gcacatggtt caggctgaca aagtaacata tgatgtttcg
    30181 tttgaatccg gaacaaaagt agctgattta gcaatcgagc gacgggaagg tcatgaaaat
    30241 tatggcatag gttcaataac taataatgat ttaactaaac ttatcgattt tgctaatgca
    30301 agtccacgtc cagtcgttat tcgatatgtt ttacaattga ctaagccatt agatgaaatc
    30361 ttagaagata tgaaagcaac agcacaagtt gaagaaaata aaccatttgg tgaagatttc
    30421 atctttgatt cttggttgtc ggatacgaat aaaaaattaa tccagaacac ttatggaaca
    30481 ggttattatt atttgcaaga tattgatggt gatggaaacc ctgacgataa agaagagagc
    30541 ggagacacga atccatatat cgggaaacct gaattagaag aagtatatga tgttgacaca
    30601 acagttaagg ggaaagtatt catccacgag ttagcgggaa caggtcacaa agcccaactt
    30661 gttgataaag aaggtactgt attagcagaa aaaactatcg ctccaaatga aaaagatggg
    30721 gctccaattt cagatactgt agaatttgaa tttacgggtg tagattcaag taaattaatc
    30781 gcgaaagatg aattaaaaat ccaaatcgtt tctccaggtt ttgataaacc agaagaaggt
    30841 tcaaccgtta ttaaggaatc accaaaagcg gttgataaac aaaccgtggt agttggattt
    30901 aaaccagatg ctaaagaatc aattcggaat aataaaaact tacctgaaga tgcagagtat
    30961 tcatggaaaa cagagcctga tacttctaac gttactgata gtacgaaagg tattgtaact
    31021 gttaagatcg gaaatcgaac tttcgacgtg gatgtagagt ttgctgtaaa agcttctcaa
    31081 gctatggaag atgatgcaac atacgtacct ataacaacaa ctccagaaac gacagttcaa
    31141 agtggaaaac ctacatttga taaaccagat gttcctttag ctaaagatgc cttttcaatt
    31201 tcagatgtct ataataagga cttcggtaat gcaagtgttg atgcaaacac tggtattgtt
    31261 acattcactc cagctaaagg tgtaggagaa tcggagccga ttactggaac aattcctatt
    31321 aaaattgttt accaagatgg ttctgtaggc acgaccgatt tagcagtaac tgtaagtaaa
    31381 gatatttatg aaaatccagg agaaaacatt cctgcaggct accacaaagt aaccttcacc
    31441 gcaggggaag gaacaagtat tgaaagtgga acaacagtct ttgcagtgaa agacggcgta
    31501 agctt
//
LOCUS       DAIGTA010000031        31334 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.031, whole genome shotgun sequence.
ACCESSION   DAIGTA010000031 DAIGTA010000000
VERSION     DAIGTA010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.031"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            1..369
                     /locus_tag="NOB43_001518"
     CDS             1..369
                     /locus_tag="NOB43_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCI0982380.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="NOB43_001519"
     CDS             549..1490
                     /locus_tag="NOB43_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCI0982381.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="NOB43_001520"
     CDS             1559..2290
                     /locus_tag="NOB43_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HCI0982382.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="NOB43_001521"
     CDS             2434..4614
                     /locus_tag="NOB43_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCI0982383.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="NOB43_001522"
     CDS             4634..5116
                     /locus_tag="NOB43_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HCI0982384.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="NOB43_001523"
     CDS             5132..5893
                     /locus_tag="NOB43_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI0982385.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /locus_tag="NOB43_001524"
     CDS             6024..7358
                     /locus_tag="NOB43_001524"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCI0982386.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="NOB43_001525"
     CDS             7665..8150
                     /locus_tag="NOB43_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HCI0982387.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="NOB43_001526"
     CDS             8143..8826
                     /locus_tag="NOB43_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCI0982388.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="NOB43_001527"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="NOB43_001527"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCI0982389.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="NOB43_001528"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="NOB43_001528"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HCI0982390.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /locus_tag="NOB43_001529"
     CDS             12442..13071
                     /locus_tag="NOB43_001529"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCI0982391.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="NOB43_001530"
     CDS             13123..13455
                     /locus_tag="NOB43_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI0982392.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="NOB43_001531"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="NOB43_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HCI0982393.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="NOB43_001532"
     CDS             14281..15654
                     /locus_tag="NOB43_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI0982394.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="NOB43_001533"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="NOB43_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HCI0982395.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="NOB43_001534"
     CDS             16709..17149
                     /locus_tag="NOB43_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCI0982396.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17293..17994
                     /locus_tag="NOB43_001535"
     CDS             17293..17994
                     /locus_tag="NOB43_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HCI0982397.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17991..19112
                     /locus_tag="NOB43_001536"
     CDS             17991..19112
                     /locus_tag="NOB43_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCI0982398.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19127..20359
                     /gene="pepT"
                     /locus_tag="NOB43_001537"
     CDS             19127..20359
                     /gene="pepT"
                     /locus_tag="NOB43_001537"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCI0982399.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20491..21399
                     /locus_tag="NOB43_001538"
     CDS             20491..21399
                     /locus_tag="NOB43_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HCI0982400.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21434..21706
                     /locus_tag="NOB43_001539"
     CDS             21434..21706
                     /locus_tag="NOB43_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCI0982401.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21717..22763
                     /locus_tag="NOB43_001540"
     CDS             21717..22763
                     /locus_tag="NOB43_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCI0982402.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23014..25623
                     /gene="clpB"
                     /locus_tag="NOB43_001541"
     CDS             23014..25623
                     /gene="clpB"
                     /locus_tag="NOB43_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCI0982403.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25774..26460)
                     /locus_tag="NOB43_001542"
     CDS             complement(25774..26460)
                     /locus_tag="NOB43_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982404.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26438..26932)
                     /locus_tag="NOB43_001543"
     CDS             complement(26438..26932)
                     /locus_tag="NOB43_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI0982405.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26952..28172)
                     /locus_tag="NOB43_001544"
     CDS             complement(26952..28172)
                     /locus_tag="NOB43_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0982406.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28319..30154
                     /gene="lepA"
                     /locus_tag="NOB43_001545"
     CDS             28319..30154
                     /gene="lepA"
                     /locus_tag="NOB43_001545"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCI0982407.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(30248..>31334)
                     /locus_tag="NOB43_001546"
     CDS             complement(30248..>31334)
                     /locus_tag="NOB43_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0982408.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        10431 a         5601 c         6715 g         8587 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggtagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aacattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 aaacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17221 tgggaatttt tttattccta gtctccttat tttatttgga aaatgctata attatctaga
    17281 aggagtgaag ctatgaacca tttagattta tctcagcgct tagccgcagt gggtgacttt
    17341 gtccctgaat ccgctcgttt agcagacatt ggatcagatc acgcttactt acccgttgca
    17401 ttgatattaa gaggaaaaat cgaatatgca gttgctggtg aagtcgttca aggtccttat
    17461 gaatcagcac gtaagcaagt caaaaaagat ggattagaag accgtatcac cgtacgcctt
    17521 gcaaatggtc tagatgctat ccagccacaa gatggtatta cagctgtcac gattgcgggt
    17581 atgggaggtt cactgatccg agatatccta gaagctggca agttgaatca acgcttaagc
    17641 ggacaagaac gtttgatcct tcagccaaac atcggagagc gtacattacg atcttggctg
    17701 caagaaaatc agtataaaat ccaatcagaa aaaatacttg aagaaaataa aaaaatatat
    17761 gaaatcattg tagccgaaaa agaacaaaaa ccagttactt acaatgaaat ggagctgatg
    17821 ttcgggccat ttctgcttga agagaaaagt gagatcttca aatcaaaatg gacaagagag
    17881 cttcaacaaa gaaaagctat ccgtgaacag ctcaaacaag cagctaatca agaggcacgt
    17941 caaaaacaaa tcgagcagga aatccaaatg attgaggagg ttttaaagcc atgacaatca
    18001 gcggacgcac tttcatccaa aagtttgaaa gctattgtcc tcagtggcta gctgaagaag
    18061 gagacccagt cggactgcat atcggaacat tggataagcc aatccaacga gtaatgatga
    18121 cattagacgt tcgtccagaa gtggtcgaag aagcaatcaa gaaaaaaatc gatttgctga
    18181 ttgctaaaca tcctccaatc tttcgtcctg taaaacggct ggttactgat cagccacaag
    18241 aaaaaatgta tgcagatttg ttgaaacatg atattgccgt ctatgcagca cacacgaaca
    18301 tggatattat ttgggatgga ctgaatgact ggttttgtga acttctcggt attgaagtgg
    18361 agagttattt agtaaagact catgagattc attataaaaa actggccgtt tatgtacctg
    18421 tggatcatgc acagaaaatg cgtgaagtat tagctgcagc tggtgctggt acacaaggtg
    18481 attataccgg tacaagtttt acctcgattg gacacggtcg atttactccg gaagctggtg
    18541 cacaaccagc gattgggaaa gtagggaaga cagaacaagt tcaagaggca aaagttgagg
    18601 ttattttgcc ggaaactatc gaaaaacaag tgattcaagc catgcggtca gctcatcctt
    18661 atgaggaacc tgcttatgat cttttcgcta tagatgaacc agtcgaaatg tttgggttag
    18721 gacgagtagg tgaattgccg caagaaattt ctatagaggc atttgtagaa caagtaaaag
    18781 aagcgttcca actagatgga ctgagaatag tccagccaaa aaatgcaaaa tcctctgtga
    18841 agcgcattgc gatttgcggt ggaagcggtg aaaaatttta tccgcaagca atcgcccaaa
    18901 gagcagatgt ctatatcacg ggagatatct attatcatac ggctcatgat atgcaaagcg
    18961 ctgggttgat tgcaattgat cccggtcatt atattgaatc gttatgcaag caacgattta
    19021 tcgagaaatt tgaatcttgg aaacaagaag aaaattggga tattaacttt ttcgtttctg
    19081 aaacaaatac aaacccattt caatttaatt aaaaggagag aatactatgt acgaaaatct
    19141 tttgccacgt tttttacgat atgtcaaaac agaaacacgc tccgatgcaa caagcaaaac
    19201 gactccatcg actcagacac aagttgcttt tgcgcaagaa ttgaaaaaag aattagaaga
    19261 gttaggctta gctgatgttt tctataatga agataacgga ttcgttatgg gaacattacc
    19321 aagcaatgtt gatcatgaag tgcgttccat tggatttatt tcccacatgg atacagcaga
    19381 ttttaatgca gtaggagtca atccacaaat cattgaaaac tatgatggcg agtctacgat
    19441 cgtactagat gcggaagaac gctatacatt gaatacaaaa gattttccaa atttgaaaaa
    19501 ttatgaaggc cacacattga tcacaacaga tggcagtaca ttactgggag cagatgacaa
    19561 atcagggatt gcggaaatca tgactgcaat ggagatcttg atcaataatc cttctatccc
    19621 tcacggtacc atcaaagtgg cttttggtcc tgatgaagaa atcggtgtcg gagcggataa
    19681 attcgatgtt gagcaattcg atgtagattt tgcttataca gtcgatggtg gtcctttagg
    19741 tgagttgcag tatgaaacgt ttagtgctgc tcaagcaaat attacgatcc aagggaaaaa
    19801 tgtacatcca gggacggcaa aagatacaat gatcaatgct ctacagttag caatcgattt
    19861 tcataatcag cttccagccg atgaagttcc agaaaaaacg gaaggatacg aaggtttctt
    19921 ccatttgatg gcattggatg ggaatcctga agaagcttct atgagttata tcattcgcga
    19981 tcatgatcgt gaaaaattcg aagcacgcaa agcacaaatc acacatatcc aagaagagtt
    20041 gaatcagcga tttgatcaag aacgaatcaa agtagatatg tatgatcaat attacaacat
    20101 gaaagaaatc attgaaaaag atatgagcat cgtggaatta gcgaaacaag caatgatcga
    20161 gcttggtatc tctccagtga tcgaaccagt tcgtggagga acagatggtt caaaaatctc
    20221 ttacatgggt attccgacgc caaatctatt tgccggagga gaaaatatgc acggacgatt
    20281 cgaatttgtt tctttacaag taatggaaaa agcaacagac gtgattgtaa aaattgcaga
    20341 attgaacaca aagagttaaa atcgaaaaag aacagcttat gacaaggcgt tcgtcccaat
    20401 gatggaatgt catctgtcta aggctaaagg gcaggacaat ggaattggtt gtcccgccct
    20461 cttttttgaa gagtaaatag gaggtaaaga atggaaaagc tgctagtttt ttataacaaa
    20521 agttcaggga aagatgaggg tgagaaatta gcacgctggt ttcaagatta tgtaaaagaa
    20581 aagcagccag aattatatgt agaactagct gaaactggcc catcgattga tgatgcggaa
    20641 ttagtcaaga aagcagaagc catagaagct gatactttag taattatagg tggagacggc
    20701 acgattcatc atatcgtcca agcgttccaa aaaacattat ctcaatacca tgtcggatta
    20761 cttccaggtg gaactgtcaa caaccttgca cgtgttcttg agattcccct caaaaaagaa
    20821 gaagctgctg acgtgatcct ggaaggcaat gtacggaaaa tagactatgg tcaagtcaat
    20881 gatgaagtca ttatctctac actgacaatc ggaatcttag cagatacagc agtttggatc
    20941 agtcaagaag aaaaacagcg ttacggctcg tggatcttta tcaagaagtt ttttaagtta
    21001 ttgctgaaga agaaaaaata tcatttggat ttagaaacag acgaggagca ttggaaagga
    21061 aaatcccaac tgttgacagt cacgatgtct aactccgtgg gcggttttac aaattttgac
    21121 gactcagcga ccctagatga tggaaaattt catgtaacga tcgtaccttc cttagatatt
    21181 ttccgattta ttttttattt gcctagaatc atgagaggca aattctatac gatccccggc
    21241 attacttatt tcacagccaa acgcatgaaa atccaagcgc aggaaaaatc tgtgggcact
    21301 cgaacggatg gagacacgac agatgatctt ccagttgaat tatctgttgt atcaaaagga
    21361 ttaacagttt attcaccaaa gaaagaagaa aaagcttaga aatagtagtt aacagaaagt
    21421 tggaagaaga gtaatggatg tattgttaca caatcctttg tggttttacc ttttcattgt
    21481 gaatttttac ttattttgtc tgatggggta tgataaacat caggctagaa ctagcggctg
    21541 gcgtgttcct gagaataatt tgatatttgt cagcctgtta ggcggtggtt tgggaggatt
    21601 gatctctcga aaagttttcc atcataaaac tcggaaaaag aagtttacta taggattcgc
    21661 tgcaggtgta cttgttgatt tgattctcat ttattttttc cattaaggag caggagatgt
    21721 cgtctaaagg aacgaaaact aaaatcattc tgaatctgct tttgctgatt gtgatttttg
    21781 ccattattta ttatttaatc aatcaatcat ttgcagatat ctttgccgaa ttgctgtcta
    21841 ccagtgttgt tgttttggca gcggctgtta tattagggac agtttaccaa atcgctgaag
    21901 ggcgctcaat caaagaaatt gctgaacctt tcgcgccgaa ttttacaacg aaagatgggt
    21961 tcttgacctc tagctatatt gcgttttacc gaatcgtttc gtttggtaca ggaacgctga
    22021 tctcggagat ttatttttat aacaaaaaag gaatgaagct atcccaggga gcaggggtga
    22081 cagcactcca tatgattatg tacaaactgg cagtgatcac ttatgcatta gctggcttgg
    22141 tcatccaatt ctctcttttt tattctaatg gtccatcaat gatctggttt atcatcgctg
    22201 gtatcctttt gacgatcgtg attgttgcct ttttattggc gatgtccgtc agcttgaatg
    22261 ttcaaatatt ttttgtcagc ttatcgaata agttatttaa aagtgagcgt ttgcggaaat
    22321 gggtggatac atgcaatcag cagatctact ctttaaggga aacggtccaa accattatcc
    22381 aagacaggac tgcgctattg cggatttatc tatggaatat gttaaaactt gtattttggt
    22441 atgtacttcc ttatttgatt ctgattgaaa accatcctaa aatagatttt ctactgacca
    22501 tttcgtttat cagctttgca gtagtgcttt caggggttat tcctacgcct gctggtattg
    22561 gttcctttga atttgtctat ttgttattat tcagaccagt tgttggaaca gttgacgcag
    22621 tttcttcgct tttactgtat cgtttcagtt cctttatctt gccatttctc tatggatttg
    22681 tgtatgtgat tgctgaacgg cgaagagtga tcaaagaaga aataatagaa gtaaaaaaag
    22741 agaataaaga aaatcaaggg taggtctttt ataagatcta ccctttttat caaatcaaag
    22801 aaaaacgtta tggataagat aattttacgt ttgtttggct ctttttttat atacatacaa
    22861 tcaattttgt ttttttaaga tttatataag tcgagaaaaa aagtcaaaaa actatgtgta
    22921 tattttgacc aaaattgacc aaagcgatat aatagttttt gtaaagatca aagaaataag
    22981 tgatcttacc tttaattagg agggtatacc tgtatgaata ttgagaaaat gactacgacg
    23041 cttcaagaag cgattgctga agctcaacag attgcggtca ctcgaaaaca tcaagatatc
    23101 gacattgccc atgtatggaa aatcttttta caatctaatc attttggtcg aaatttctat
    23161 acggatgccg gattggatgt cgaatctttt gaacatgaaa ttgatcgtct actggatgag
    23221 tatccagttg tttctggtgg aaacgtccaa tatggacaaa acctcagcca gaatttcttt
    23281 cgattattga atgaagcaga ccaaatacgt gaaagcttcg gcgacgagtt tctttcaacg
    23341 gaagtcgtta ttttagcgtt gatgaaatta aaaaattatc cgttaactgt ttatttgaat
    23401 aaaaacggat tatctgaaaa agaattgcgt aaaaacatcg aagagatgag aggaggagaa
    23461 agagtgacct cacaaaacca agaagaacaa tacaaagcat tagaaaaata cggcgttgat
    23521 ttagtacagc aagtcaaaag cggaaaaatg gatccaatca tcggtcgtga tgaagaaatc
    23581 cgtgatgtca tccgtattct ttcacgaaaa acaaaaaata atcctgttct gataggagaa
    23641 cccggtgtag ggaaaacggc aatcgttgaa gggcttgctc aacgtatcgt acgcaaagat
    23701 gtgcctgaaa atttaaaaga taaaacgatt ttttcattag atatgggtgc attgatcgct
    23761 ggagcaaaat tccgtggtga atttgaagaa agactaaaag cagtcttgaa agaagtcaaa
    23821 aaaagtgatg gacgtatcct cttgttcatc gatgaaatcc acaatatcgt aggggcagga
    23881 aaaacagaag gaagtatgga tgccggaaat ctgttgaaac caatgcttgc tcgcggtgaa
    23941 ttacatttga tcggtgccac aactttagat gagtaccgtc aatatatgga aaaagacaaa
    24001 gcgttggaac gtcgctttca aaaggtatta gtcaaagaac caacagtgga agatacgatc
    24061 agtattctgc gtggattaaa agaacgtttt gagatccacc atggtgttaa catccatgac
    24121 aacgcattag tagcagcagc tactttatct gaccgttata ttactgatcg gttcttaccg
    24181 gacaaagcaa tcgatttgat cgatgaagcc agtgcaacga ttcgggtaga aatgaactct
    24241 atgccaacgg aattagatca agttactaga cgtttgatgc agttggaaat cgaagaagct
    24301 gcactgaaaa aagaatcaga tgatgcaagt aaaaaacgct tgaaaaattt gcaagaagaa
    24361 ttagctgaac ttcgtgaaga agcaaatgcg atgaagatgc agtgggaaac agaaaaagaa
    24421 gaagtcaatt ctgtttcagc aaaacgtgct gaaatcgata aagcaaaaca cgaattagaa
    24481 gatgcagaaa ataactatga tttagaacgc gctgctgtat tgcgtcatgg tacgatacct
    24541 caattagaaa aagaattgaa ggaattagaa gctaaagcaa aagacagcga gattaagatg
    24601 gttcaagagt ccgttaccga aaatgagatt gctcaagtcg ttggcagatt aacgggtatc
    24661 cccgtaacga aacttgtaga aggtgaacga gaaaaactaa ttaaattgaa tgaaacactt
    24721 cataaacgag tgattggtca agatgaagca gttgatgcgg tcagtgacgc ggtaattcgt
    24781 tcacgggctg gattgcaaga cccaaatcgt cctctaggtt ctttcctttt cctaggacca
    24841 actggtgtcg gaaaaaccga attagcgaaa gcgttagctg agaacttgtt tgactcagaa
    24901 gatcatatgg tacggatcga tatgagtgaa tatatggaaa aacatgctgt gtctcgtcta
    24961 gtcggagctc ctccaggcta tgtaggttac gaagaaggtg gtcaattaac ggaagctgtc
    25021 agacgaaatc cttatacaat cgtcttgttg gatgaaatcg aaaaagcgca tcccgatgtc
    25081 ttcaatatct tgttacaagt cctagatgac ggacgcttga ctgattcaaa agggcgagta
    25141 gtagatttca aaaatacggt tctgatcatg accagcaata tcggttcaca gttactgctg
    25201 gaaggcgtga ctgctgatgg aacgattcca gaagcagtgg ctgaacaagt caacacgcta
    25261 ttacgtggaa acttcaaacc agaattcttg aaccgaatcg acgacacgat tttatttaca
    25321 ccattgagcc tagacaacgt gaaaggaatc gttgacaaaa tggtggcgca attggcacaa
    25381 cgtctggaac atcaagaaat cctgctgaca atcagtgatg aagccaaaac gtggattgct
    25441 gaaaatgctt atgaaccagc atatggtgca agaccattga aacgatttat cactaaggaa
    25501 gtagaaacac cactagctaa agaaatcgtt gcaggacatg ttatgcctaa atcaaaagta
    25561 acgattactt tacttgatgg acaacttcat ttcaaaacag aagagctaga agaaatcgtc
    25621 taatcttcca ttgagactat aaaagaaaaa aggggtctga cacaactagt gtcagacctc
    25681 cttttttcaa ataaacagtg ttccagaagt agtttcttcg aaaaataagc cgaaatttct
    25741 tgaagctgcc cgcttctgtc acaacctctt ttattaggta tttttcactt tttctaattt
    25801 ataactttca aagtaacgct catctttttt actttgagac catgcaaaca atcccattaa
    25861 ggcagcacct atcgtatttg tcagcaagtc gcccatcgta tccatcaatg ctgctcgtcc
    25921 gacaaacagt gtgccatcag aagcagcaaa acgttgaaga ttcatgccta agaactggtc
    25981 gcataagaat tcccagaact cccaaaacac gccgcaaagt ccagcaaacg caaagccgaa
    26041 taagaggaac aaccaaggac tggtttttga tatctcagca tctttcatca agtaaccaat
    26101 caatccatag ccaagagctg tcaggaccat tggactcacc gcatgtaaga ttttgtccca
    26161 aaaagagatg atactgatca aatgcatccc tgtgcctaaa aagacagaga tgaacaagaa
    26221 aaaccagtaa aacaaaacga ttgctgctgg tattttaagt ttgaaaactt tcaaaatgac
    26281 ttgtggcatg aaaatcaatg caatccctaa taaagattcc acgataaatg tgattccttg
    26341 agaagtcgaa tatttttgtg tgataaattc ataaaaatta tagcagacaa cgaatacacc
    26401 aaaagcaagt aaagctattt gcaccttttt gatttcttta atcactgaaa gtccctccat
    26461 ctaaaaatct ttttacttct gaaagcaact caatttctga agaaaccact tttccgttca
    26521 atttgatcaa acctattgta tataagttca ggtagtgaaa ttgattttca gctgtttctt
    26581 gtagtgcagc gatttttttc gggtgggttc cgccttgctg tcgagtatca gtatataagc
    26641 cgatcactgg gatgcctttc gcataagcca caccgatttc cgatgctacc ccggcatcga
    26701 tcgtcagccc atctagtaaa gcaatcatta aatcactagc caacactttt tctgtgtcag
    26761 caagagcaat cattcgactg tctgcataag cagttttgtc attgattgct tcattttctt
    26821 gaggaagata gatcgaaagc tcagaagaga gctctctgat ttctttaact aactgttggt
    26881 tatataacaa atcactttta gcaaacattg gtgcggcaaa ataaattttc atctaaacat
    26941 catccttttt atcaaaaata atcgctaaag taagcttcca tgtttggaat gatacgctct
    27001 agtgacttca gtgtttcttc atctgtttct aaccgttcga ttcttgccaa ataagaagca
    27061 cggcgataat tcatcatcaa gcaagtcaat gtttggatat ccagtcgaac ggattttcct
    27121 ataggttcat ttaagacacg gacttgtccc tgttcatccc atgttaaagc gaagacacca
    27181 ttattccaag gagcgacagg atcttcaatg atgaaatgaa aagcatcagc tgttccaaca
    27241 aacggaaacc gttgaaggaa ttcttttaca tcaacgatcc gagccataaa atatggttcg
    27301 atctgctctt tgatctgact atcttcaatc aaaaatgcta aaggctcatt tttataaata
    27361 tctccatgta cccagtagat catggaaaaa tgtgcggaaa taaagttcca taagccattt
    27421 cgagcttctt gatcaagata gaacatttct tttacgtgaa atatttcttc agctacccag
    27481 tagaacagaa cacctcttgg ttcatggttg ctatcgtagt agacagcggc tgtgcgctca
    27541 tcttcatttt cgaaacgcca atactcttcc caatgaaaat cactgcggaa taaagcacca
    27601 tggttttgtt gggcaaattt gtcataaacg gaaaatacgt ctggatgatc aactggtaat
    27661 cgctcaacca taccacttac tgggatttgt ttaggtagct gtgtatctct gattttaaag
    27721 gaaagtttat cagacatgat ttcccatcct ttacgccgat agtaggggat actgtaagga
    27781 tacaaataag agatccattg cttattcttg cgcatattat ccaatgcaac gataattaga
    27841 tcttgcatca atccatggtt agcatattct ggataagttc caactccagt cacaccaccc
    27901 attttataac gtgcaccgtg aatattgact tcacaaggat agatagcgat ttgagagatc
    27961 agtttatttt cgtggaacca tccgaacact ttcgatactt ccaaaatcgg ttttttggaa
    28021 cggataaaag ctcgtttatt ctcaaacccg ctttcctcga tgtctgcttc agtcacttgg
    28081 aacacatagg aaagcaattc attgaattga tcgatatgtt cttgagtgac cggttttaat
    28141 tcaagatttt ctctaaaatc tttttgatcc attttttcat ctccatttat tagcttgata
    28201 acagtatagc aaaattctac aaaaaaaact tctatagctg actaattaaa aactctttaa
    28261 attactgctt ttcgttggta taatggaaag tgctgattat atgaaaagag gagacgctat
    28321 ggatataaag aaaatgaaag aacgccaaga gcagattcgt aatttttcga tcatcgctca
    28381 tatcgaccat gggaaatcta cattggccga tcgtatttta gaaatgacgc acactgtgac
    28441 gtctcgcgaa atgcaagatc agctgttaga ctcgatggat ttggaacgtg aacgtggaat
    28501 cacgattaaa ttaaatgctg tagaactcaa ttacacagcg aaaaatggag aaacatatat
    28561 ctttcacttg attgacaccc cagggcacgt cgacttcacc tatgaagtct ctcgaagcct
    28621 tgctgcctgt gagggtgccg ttttagtggt cgatgcagca caaggaatcg aagcacaaac
    28681 attggccaat gtttatttag cgttagacaa tgatttggag atcctgccag tcatcaataa
    28741 aatcgaccta cccgcagcag atcccgaacg tgtccgtcaa gaaatcgaag acgtaatcgg
    28801 aatcgatgct agtgaagctg tattagccag tgccaaatca gggattggga ttgaagatat
    28861 tctcgagcag atcgtggaat atgttcctgc accaagtgga gacttagatg caccgctaaa
    28921 agctttgatc tttgactcta tttatgatag ttaccgcggt gttgttctaa atgtccggat
    28981 cacggacggt atggtcaaac ccggagacaa aatcaaactg atgagtaatg gcaaaacatt
    29041 tgatgttaca gaggtcgggg tcttctcgcc aaaagcagtt gctagagact ttttgatggt
    29101 cggtgatgtc ggttatatca cagcaagtat caaaactgtc caagatacac gagtagggga
    29161 tacagtaacg ttagcagaca atcctgccgc tgaagcttta ccaggttacc gaaaaatgaa
    29221 tccgatggtt tattgtggtc tttatccaat tgatacttct cgttacaacg atttgcggga
    29281 agctttagaa aaactgcaat tgaatgatgc tgctttacaa ttcgaaccag aaacctctca
    29341 agcattaggt tttgggttcc gctgtggatt cctcggactt cttcatatgg atgtcgtcca
    29401 agaacgcttg gaacgggaat tcaatctaga attgatcacg actgcaccat ccgttattta
    29461 ccatgttaat aaaacggatg gtacgactgc tacagtagat aacccggcag attttcctga
    29521 acctgtaacg attcaggatg tagaagaacc attcgtcaaa gcacagatca tggtcccaaa
    29581 tgattttgtc ggtgcagtaa tggaactttc tcaacgaaaa cggggagaat tcattacgat
    29641 ggattattta gatgattacc gagtaaatgt cgtctataat attccgcttt ctgaaattgt
    29701 ctttgacttt ttcgacaaat tgaaatcaag cacgaaaggc tatgcctcat tggattatga
    29761 aatgtctggt tatcaaaaaa gcaagttagt gaagatggac atcttgctga atggagaaaa
    29821 agtcgatgca ttaagcttta tcgttcaccg agactttgcc tatgaacgtg gaaaagcaat
    29881 cgttgaaaaa ctgaaaaaac taatcccacg ccaacaattt gaggtgccaa tccaagcagc
    29941 tattggacaa aaaatcgttg cccgttcaga catcaaagcc ttgcgtaaaa acgtcttggc
    30001 taaatgttat ggtggagatg tttctcgtaa acgtaaactc ttagagaaac aaaaagaagg
    30061 gaagaagcgg atgaaacaaa tcggctccgt cgaagttccg caagaagcct tcatggccgt
    30121 tctgaaaatg gacgaggacg aaccgaagaa atagcaaggg tttgtttgaa aacagtgtaa
    30181 aaaataaacc atgtttacat ggatttgcca ccggtttgcc accggtggtt tttttcggtg
    30241 gcaaaaatca agaattcttt ctaagatttt ccatgatatc gaccgtttca tttctcatct
    30301 tatctgttac atgcgagtaa gtatccatcg taattgaaat tctgctgtgg cccaatcgtt
    30361 cagagatttc tttcattttt gcgccatttt cgagaagaag tgtagcatga gtatgtctga
    30421 gagaatggaa gttaaaagag agggagagtg cattcgatat cctcctagta ttccatttca
    30481 ctacacttgg cgtaactagc tcaccgtctt ccttcgtaca tactgcattt gaatcaatgt
    30541 agagctttcc atacttcatt cgattttcta attgttgttt cttatgtttt ttcagaattg
    30601 ctagcaaggt ttgtccaata aaaatcgttc gattggaact gcttgtcttt ggcgtaccat
    30661 atacccatgc gccgtcattc tttaccattt gtttctctac agtaattgtt ccatttgaaa
    30721 aatcgacatc atcccacgtc agaccacaaa cttcgccaac gcgcattccc gtataaaatc
    30781 caatattcaa aggaatatag aaaggatgtc cttcaggagt aatttctagc atatgatcaa
    30841 agtcctcaag agaaatgatt tttagatctt ttttagtcgt tggtcgtgct tcatattttg
    30901 gtatttttac atacagcata ggattttgct tgattaatcc ccaaggataa accgccatat
    30961 tcagcgcatt cttaaggaca gagtgagtaa tagtcattgt tttcttcgag taaccctttt
    31021 taaattcagc attgatgaaa ttttgtaaaa gagcagggga gagatccgta agttttttct
    31081 ttcctaaata accgtttata tgatttttga tggtaaatcg gtagttttca taggtattgt
    31141 attttagatt tagtttaacg tattcctcca tccaaaaatc aaggtattgt tttactcgag
    31201 tatccgtacc taaaaagtat tgtcctgttt cgtcaatatc tgataaaact tttcgtaaag
    31261 cagcttcggc ctctggtcgg gtgtctccgc caactttctc cacttttttt cttgagccat
    31321 catcattgat atct
//
LOCUS       DAIGTA010000032        30847 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.032, whole genome shotgun sequence.
ACCESSION   DAIGTA010000032 DAIGTA010000000
VERSION     DAIGTA010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.032"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(118..663)
                     /locus_tag="NOB43_001547"
     CDS             complement(118..663)
                     /locus_tag="NOB43_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0982409.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(675..1367)
                     /locus_tag="NOB43_001548"
     CDS             complement(675..1367)
                     /locus_tag="NOB43_001548"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCI0982410.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1386..1670)
                     /locus_tag="NOB43_001549"
     CDS             complement(1386..1670)
                     /locus_tag="NOB43_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982411.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1683..2246)
                     /locus_tag="NOB43_001550"
     CDS             complement(1683..2246)
                     /locus_tag="NOB43_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0982412.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2474..3136
                     /locus_tag="NOB43_001551"
     CDS             2474..3136
                     /locus_tag="NOB43_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HCI0982413.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3260..4456
                     /locus_tag="NOB43_001552"
     CDS             3260..4456
                     /locus_tag="NOB43_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCI0982414.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4557..5933)
                     /locus_tag="NOB43_001553"
     CDS             complement(4557..5933)
                     /locus_tag="NOB43_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0982415.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5970..6836)
                     /locus_tag="NOB43_001554"
     CDS             complement(5970..6836)
                     /locus_tag="NOB43_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HCI0982416.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6925..7950)
                     /locus_tag="NOB43_001555"
     CDS             complement(6925..7950)
                     /locus_tag="NOB43_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0982417.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7968..8642)
                     /locus_tag="NOB43_001556"
     CDS             complement(7968..8642)
                     /locus_tag="NOB43_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0982418.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIKGYIETKVG
                     QGYIVP"
     gene            complement(8826..9719)
                     /locus_tag="NOB43_001557"
     CDS             complement(8826..9719)
                     /locus_tag="NOB43_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0982419.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9793..11490)
                     /locus_tag="NOB43_001558"
     CDS             complement(9793..11490)
                     /locus_tag="NOB43_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0982420.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11483..12796)
                     /locus_tag="NOB43_001559"
     CDS             complement(11483..12796)
                     /locus_tag="NOB43_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCI0982421.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12796..16833)
                     /locus_tag="NOB43_001560"
     CDS             complement(12796..16833)
                     /locus_tag="NOB43_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI0982422.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FHHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16846..17304)
                     /locus_tag="NOB43_001561"
     CDS             complement(16846..17304)
                     /locus_tag="NOB43_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0982423.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17602..18120)
                     /locus_tag="NOB43_001562"
     CDS             complement(17602..18120)
                     /locus_tag="NOB43_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI0982424.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18122..18739)
                     /locus_tag="NOB43_001563"
     CDS             complement(18122..18739)
                     /locus_tag="NOB43_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCI0982425.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18736..19590)
                     /locus_tag="NOB43_001564"
     CDS             complement(18736..19590)
                     /locus_tag="NOB43_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0982426.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(19587..20498)
                     /locus_tag="NOB43_001565"
     CDS             complement(19587..20498)
                     /locus_tag="NOB43_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0982427.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20539..21873)
                     /locus_tag="NOB43_001566"
     CDS             complement(20539..21873)
                     /locus_tag="NOB43_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0982428.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            22081..22911
                     /locus_tag="NOB43_001567"
     CDS             22081..22911
                     /locus_tag="NOB43_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCI0982429.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23155..23473)
                     /locus_tag="NOB43_001568"
                     /pseudo
     CDS             complement(23155..23473)
                     /locus_tag="NOB43_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23595..23789)
                     /locus_tag="NOB43_001569"
     CDS             complement(23595..23789)
                     /locus_tag="NOB43_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982430.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(24294..24479)
                     /locus_tag="NOB43_001570"
     CDS             complement(24294..24479)
                     /locus_tag="NOB43_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982431.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(25329..25670)
                     /locus_tag="NOB43_001571"
     CDS             complement(25329..25670)
                     /locus_tag="NOB43_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0982432.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(25670..25900)
                     /locus_tag="NOB43_001572"
     CDS             complement(25670..25900)
                     /locus_tag="NOB43_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0982433.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            26187..26525
                     /locus_tag="NOB43_001573"
     CDS             26187..26525
                     /locus_tag="NOB43_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982434.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(26730..26969)
                     /locus_tag="NOB43_001574"
     CDS             complement(26730..26969)
                     /locus_tag="NOB43_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI0982435.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(26945..27292)
                     /locus_tag="NOB43_001575"
     CDS             complement(26945..27292)
                     /locus_tag="NOB43_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI0982436.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(28024..28605)
                     /locus_tag="NOB43_001576"
     CDS             complement(28024..28605)
                     /locus_tag="NOB43_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0982437.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(28788..29414)
                     /locus_tag="NOB43_001577"
     CDS             complement(28788..29414)
                     /locus_tag="NOB43_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0982438.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(29436..30767)
                     /locus_tag="NOB43_001578"
     CDS             complement(29436..30767)
                     /locus_tag="NOB43_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HCI0982439.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
BASE COUNT         9098 a         6595 c         5238 g         9916 t
ORIGIN      
        1 aaaaagaata agttttttta aaataacgta taaaaaagag cataaaacaa agtcgtttgt
       61 tttatgctct tcttttatta ttttgtgctt tttattttat caaatcactt tgttttttta
      121 taaaatttct gcgcctagtg tggactcaaa atgtctcaat gcccattcat gtccaacggg
      181 atcgaaactt gccacggaat ctttgaaaat atggagtttg tatcctagat tatacgcatc
      241 gactgctgta tgcaacacac agatatctgt acatacgccg gtcaaataaa tatctgtgat
      301 ctggcgttct cgcaaacgga tgtctagatc tgttccacta aaagcggaat aatgccgttt
      361 gtctatccaa taaacatttt cctcttgctc atagtcttgg tataaacttt ttaaagagcc
      421 gtacaattcc cgtccacccg ttcctatcac attatgcgga ggaaataagc ggttctccgg
      481 atgaaaggaa tcttttggat catgcgcatc aatggcaaaa acgacaaaat ccttttgatc
      541 aataaacttc tttgtatgag cagtcagctt tttttcaatt acttgtcctg ctgtcccagt
      601 agtcagcttt ccatcctctg caacaaaatc atatgtgtag tcaatcgaga tcaatgcgtt
      661 catcttagtc ctccttatac gagatgtttg acaaattcga tcaccatttc tgctgatcgt
      721 ttgcctgcgt cttcgataaa ttcgtcaaag ctttgtgtcg ccgagtgatc tgctgtgtcg
      781 ctcattgcac gtacgatcaa aaatgggata ttgaactgac gagctgtttg tccaacagcg
      841 gctccttcca tttcgcaagc taatgcttca gggaaattcg ttaagatttc tttgatttta
      901 tctggcgagt cgacaaatgt atcacctgta acgatcaatc cttcttttgc gttcaaattc
      961 gttgcttttg ctgctttaac catttcactg cgcaaatatg tgcttgcttc ataatataga
     1021 ggcattcctg gtaattgtcc tgggttgtag ccaaatcctg ttgcatctgc atcaaaataa
     1081 gctactttgt ctgatataac gatgtcacct acttgtaagc cttcaccgat tccgccagct
     1141 gaacctgtat tgatcaccat gttcacgccg tattgttgga tcaacagact tgtggtaata
     1201 gatgctaaga cttttcctat accggaacgt acgacgatca cttcgtggtt acctaatgaa
     1261 cctgaaataa ataaagcgcc tgcgcgttcc catgataatg gttcgcttag gttctctctc
     1321 aaaattttta cttcttcttc cattgcgccg ataataccga ttttcatctt tttaattcct
     1381 tctttctata taaatgcgat tgctaaaaaa accacacata acattaggat aacaataata
     1441 agagatttca tcaaaaaaga gttccatttg gtcgtctttt cccgttcgct gatccttgtt
     1501 ttcgtgattg gtttattctt tttgctttct ttacgataaa agctggcaat ctttttttct
     1561 tcttgctgat aagctgtttc tgcttttcgc tgttttttta atgactcgct tgcttgtgct
     1621 tgttgtcgct tgcgaagttc gcttcgcgta ataagcggtc ctttggccat aagccgatcc
     1681 ctctactttc ctttggtcaa tagttcccag tattgaatcg cataaatcgt ctttgcatca
     1741 caaatcaact gatctttcat cgcttgttgc gcctcttcaa gagttagatg atacaactcc
     1801 agtacttcgt cttcatcttg tgctaaagga ttctcgacct tctctacccc ttgtgcatga
     1861 taaatatgaa ggacttcatt tgcaaaacct ggtgaaagat acatcgaagt aagatggctc
     1921 agcgacttcg cacgatagcc agtttcttct tctaattctc tagctgctgt catttcggga
     1981 ttttgtcctt ctcctggatc gatttttcca gctggaatct ccaaaatcac tttttctaaa
     2041 ggttttcgaa attgtttgac aagaagcaga cgatcttgtt cgtcaaaagc aatgatcccg
     2101 acaccgccag gatgaaatac cagttctctc ttcgaagttc ctccatctgg caaacgaact
     2161 tcgtctacag caacatcaat aatttttccg ctatagattt ctttgcgact gattgttttt
     2221 tcttcaaatt gctcattgtt cagcatatct tctcctgctt tctttgtaat cataactgct
     2281 tttttttcat ttttcaattt ttctcaaaaa ctccttatta gtttaccata gataaacctt
     2341 agattttctc taaatataga aaatccttct ttagtccgat actctttcta gtagtccgta
     2401 tgctaaaata agtatgtaat cgaataacga aaagaattca atactcaacg ataaatgaca
     2461 tggagggttt attatgataa aacgaaattg gccgtggctt ctagcattgg tcttgctatt
     2521 tctctttgtc cgaaacaata gtttttcttt tgttctagga cttttattga taggtgtagt
     2581 tttagttttg tggggactct ttggttcgcg caggaaaaag ggaaaacaag aagaaattcc
     2641 tgcactgact gacgaacttg aaactcacta tgaaaaaagc ggtatgacag cgaatgaaat
     2701 ttcatttttt cgacaaacaa tgaatcaaac aaaaaatgag atcaatcaat tgcaaatgaa
     2761 tatgcagcag acagccaaac ttaaagcaat cgatctccgc catgatccag tcaaagcagc
     2821 gaaagcttta ttcaaagaat tggtgaaaga accaaaccga ctgcatgaag caagtcagtt
     2881 tctttatacg catctgccga atctagttga tttgacaaat aagtataatg agatcaatga
     2941 ccatgagatc aaaaacaaac agacctatga aaaactagaa gaaagcgcgc agatcatcga
     3001 ccagctgtca gctttaatcg cacaagatta tcaaaaattc gttgctgagg atctagatga
     3061 tatcgacgta gagatatctg ttgcgaaaca gagcttaaag cgtgataata aatatgaacc
     3121 agaacaaaag gattaactct tttgttcata aaagaagact cggaacattc agatgatgtc
     3181 tggctgtttc gagtactttt tctaaagtag agacattcat gtaagaatcg agaacagatt
     3241 caacaaggag gaatttttta tggatcataa accgactgaa acaaaagatg ttacaccagt
     3301 taacgataca cttgaagatt tattgaacaa cccgttttca actccaacag atacgctgac
     3361 cacttcacaa caagcggaga ttgatcagct ccaagagcaa cagacagctg ctcgtttaat
     3421 tgacaaacta ccggcggaac gccaagaaca agctaaacag ctagcagcaa aaatcgatgc
     3481 taatgatgca cagtctgtca tcagctacgg atcggctgcc caagcaaaat taagtgaatt
     3541 ctcacaatcg atgttgaatc atgtgcaagc acaagatatt ggtcctgtag gagattcctt
     3601 aactgaactg atgtatcgtc tccaagaagc caatcctgac gaactgcgtg ccggagaagg
     3661 gaacatcttc cagcgtgtct tcgggaaggt caaacaatcg atctatgaag tgacagcaaa
     3721 atatcaaaag attggtgcac aaattgacaa gatttcagtg aaattagata aagaaaaaga
     3781 cggtctgcta aaagataatc tgatgttaga acagctttac cagaaaaaca aagactactt
     3841 tgatgcactg aatatttata tcgctgctgg agaattgaaa atggaagaac ttcaaacaac
     3901 gatcattcca gaagcgatga aaagagcaga agaaactggc gatcagatgg atgttcagat
     3961 tgccaatgat tacacgcaat tcctagatcg tctggataaa cgtacgcatg atcttcgctt
     4021 agctagacag atcacgatcc agcaagcacc acaaatccgt ttgatccaaa acacaaatca
     4081 ggccttggct gaaaagatcc aagcatctat cgctacagcc attccgctgt ggaaaaacca
     4141 agtcgtgatc gcattgacct tgcttcgtca aaaagatgca gtaactgctc aacgccaagt
     4201 ctctgaaaca acaaacgact tattgaagaa aaattcagaa atgctgaaaa tctcagccat
     4261 cgaaacagcg aaagaaaatg aacgtggaat cgtggatatc gagacccttc aaaccactca
     4321 aaatgatttg atcgaaacaa tccaagagac attgcgtatc caaaaagaag gaaaagaaaa
     4381 acgtcgtcat gcagaagtag agcttggaca catggaagaa gatctgaaac aaaaactgtt
     4441 ggatttaacc caatagatca cctttcgctt gttactaaaa caaacgccca acaacagttt
     4501 attacaactg ttgatgggcg tttttcttat ctttcttcta acttctccat tggagtctat
     4561 ttctcattca tcttgctgtg tccatagcca tagccaaaat aaatgatcag tccaataacc
     4621 attacgatac cgaacacgat ccatgtcaca gtttgcagac gaagcatcaa tacaatacaa
     4681 gtcaagatgg agacgattgg caatagcgga acgaatggca ctttgaattc tccagctttt
     4741 ggtttgccaa acatttttct caacttcagt aagcctagac taacaagcat caaataggcg
     4801 agcgccatga tattcgttag ttccgctaat acattcaatg ggaaaaatcc ggcaaagaat
     4861 acagctgcca caccagcggc ataagtcgct tttttcggtg tacgatgctt ttgatcgatt
     4921 tctgtcataa acttaggaag taagccatcc ttgctgacag caaacagtaa acgagcaagt
     4981 gaatacatca tcgagatcgt taccgtcagt agcgttaaaa ttgcccctac agcgatcacc
     5041 gcgcccactg ttccatgtcc tacatacctc attgcaaaag ccactgggtc attgactcct
     5101 agttcagtat acggaacgat tcctgtcaag atcagcgtca cgatgatgta aaggacagta
     5161 gcaatcagta tcgaaccaat gattcctctt ggcacatctt tttgcgggtt tttgacttcc
     5221 tcggctgcca ttgcaacggc atcaaatccc aagaaagcaa aaaacacaag agctgcacca
     5281 tctagcacac cggaaaaacc aaaaggcatg aatggctgcc agttatcagg tttaacgaaa
     5341 aatattccta caatgataaa caacgcgatg ataccaaatt tgacatatac catggcatta
     5401 ttcaaacgta atgctttctt ggcttcaagc gacacgatgt aagtgacgaa tatcactacg
     5461 agcaccgcaa tcaagtcaat gtatgtacca ttttccggat tgtacccgcc agttaatgct
     5521 tgtggaagtt cggcccctaa acttttcaaa aaaccttgca tatagccaga ccatccggaa
     5581 gcaacagagg aaaccgctag taaaaattcc ccgatcaaca accaccctgt cagccaggca
     5641 gcaaattcac caaatacaac atacagatag gcatatggcc caccaatcac tggcactcgc
     5701 gaagcaaatt ctgcgaaact tagtccagac aaaatgacaa cgattgcagc taagacaaat
     5761 gaaagtgaca gtgctggacc agcattttga ttggccgcaa cccctgtcac cacaaatatt
     5821 cccgtaccga tgatcgcacc aattccaagc atgatcaaat cagacgtttt tagttctttt
     5881 ttcatctcac tcgtatgatt gagattgatc tctttcttac gaaacaaatc cattgaagtt
     5941 cctccccatt ttaggttgga aaacagcgat taaactgttt tcatataccc taaaaggata
     6001 ccacctaaaa tgactaaaag gcaaccaaca ataacataaa tgagctcttt tttcgttttt
     6061 ctttcgccaa ggatgaaaat cccacctaaa gtagagataa tgatccccat ttgtgaaagt
     6121 gagaagccaa cagctaaacc aagtgatttg actgttagaa gcatgcagat gtttcctaag
     6181 ccccataata atccacagat catgtttttc cacacaaact gatcgacttt aactttacgg
     6241 aaagcaaaga agcttgcgcc taagatcatt ccgatacttt gaggtaagat aattgacatc
     6301 gcatccaaat tcgcccagtt gacgatgatg gtatatacac cataaccaat cgtagagaag
     6361 atcaatgctc taaaaccctt accaaaatca agcattttat tatctgtatc tatttttcct
     6421 tcgtcatctt gtcgggcagt caaatacgca ccgcttacaa gaagagctaa agcaataata
     6481 ccgtatacat aatctttcgt ttgtgtccat tcatggaaga aaacggctcc cgcaatcgta
     6541 ttcaaaatta attgaaaacc agtagacaat ggtagcccta cagaaacacc catgtacttc
     6601 attccatgga actgtccatt ttgtccaaca ctccaagcta agccggataa aaatccgatc
     6661 aagaaaatcc aaggggtgat tacaggacta acaacgaaaa agacaactaa agaaaacaga
     6721 aatgcaccga tcgtcattcc tagtgtttgt tgattggcat cgccaccaat tttaccactt
     6781 actaaaccaa tactacccca tgccaacata gggactaatg ctattaaaat ttccataacc
     6841 aatctccttt tatttcacat gataagaaac ttatcagcga aaacgttaac aacacaagca
     6901 ctttttttcg tttctaacga ttttctaacg tttttcatta taaaaattta agattgggaa
     6961 aaataaagtc attgttgtcc cttttccttc agttgattca gccgtcaaat ggatacctaa
     7021 tttttcggcc agattttttg ctaaataaag tcctaatcct gttgaatgtg ttttgctaag
     7081 tcgaccattt ctcccagtaa atcccttatc aaagatccgt ttcaagtctt ccgctgggat
     7141 accgatccct gaatctttaa ctgaaaggct gactccttgc gcttcctttt ctatgctcac
     7201 aatgatgttt ccgtgatccg gcgtatattt gatggcatta ctaagcaatt ggttgaagat
     7261 aaaagcgatc catttagcat cggtcaaaac agtatgatcc tcaccaacga tctcgtagcg
     7321 aatatttttt tggataaaat aatttgcctg actgcgtatc acaggctgaa tgattccttt
     7381 tagtccatat tcttggatga ggtagtcccg cgagaaactg tcgagtcttg cataatacaa
     7441 aacttgttct acgtattcat cgatttttga taattcattt tctagtaatg tatacttttg
     7501 atcgtcaata tcgaactcga tcgaacgaac tagcaattta gaagcggaaa gtggcacttt
     7561 gatttcatgg acccatgagt caatataatc tttttggtct tgttgattac tgattgctga
     7621 ttgcattact tcttggtgtt cacggatcag ctgattgata tattcttcta ccagtttttc
     7681 ttcttctgtc ctcccaccac tcaaataatt ttgcaaaggg gaagtttttt gtatgtcggc
     7741 taattttccc caccatcttc tcttgctcaa gtaaccaccc agcagataaa aaatcagaaa
     7801 gacgccctca atcaaagcta aataagcaat tgtgctcaaa tcaactttga tgtttggcgc
     7861 cagccacatc acaaagatcg tcaatgcaat aaaaaacagc catcccaaga tcaatgtcca
     7921 ctgatctttc aaatatttaa aaaaattcat cttaaccgct catcctttca gggaacgata
     7981 tatccctgtc ctacttttgt ttcgatatat cctttgatac ctgcctgttc gatttttcgg
     8041 cgtaaccgat tgatgttgac tgtcaatgta ttgtcatcta caaatcgttc gtcatcccac
     8101 agtgctcgca gcaatttttc ccgacttaag atctttccat tgtgcttcat caaaataaat
     8161 aatagacgat attcattttt gctcaaatca atgatctctc cgttgatttc catacttccg
     8221 ttgtcaacat tcaacgtaat gccattgtgg ctcatcattt cactagataa ttctgtgtag
     8281 ttgtaagaac ggcgaagtaa tgcattgatt tttgcaatca gtacatcgat ttggaaatgt
     8341 tttgtcacaa aatcatctgc ccccatgttc atagccatga tcatatccat attcgtattc
     8401 ctgctggaga taaaaatgat cggtactttc gatacttcac gtattttttg acaccaataa
     8461 tagccatcca aaacgggaag attaatatct agtaatacaa gctgtggttc ttctctttca
     8521 aagtctgaga acacttgatt gaaatcggtc gttccaaagg tttcaaattg ccatttctca
     8581 agttcctcca tgatcaattg tcgaatgatc tcttcgtctt cgactaccat gatttttgcc
     8641 ataaaaaatc cctccatctt tcttcttgct actacaatat caaagaagcc cttgtgaaac
     8701 aagttggctt acctggaaaa tgtcatttta gcaaacgtta aaaaaaactg gaaatatgcg
     8761 atttaatcgc gtttgtctct tccaagcagc ttaaatttat tatgttattc ttaataattg
     8821 gtctattatc tgttattttt ctttcgttgt ttttgtcttt taaattttcg ataacaccaa
     8881 taaccgaaaa gcgttagcac tagcaatata cctagaagga gtataagtaa tcgataaaga
     8941 tggtattttt ttgtctgttc tatctttgaa gagacttctt ctgtaaaggg aactcgtctt
     9001 cctgtcacta gtaatcggtg agtgttcacg gtgtaaggtg tacaagtgat aagtgtgact
     9061 agatcctgct tttctctaat tgctaatgta tttgtttttg ttggaaggac aacaattttc
     9121 tcaacgactt cataagcgag catccgacca tacacttcaa gatagaatcg gtcatcttgc
     9181 tccatttctt caagatccgt aaagagtttt ttctcagcaa taccgctatg ggcggtaatc
     9241 acggaatgtg tactctctcc tccagttgga aaagaggtgc cttgcaggac tgtcgctcct
     9301 ctatctaaca aaagatcatt cgtttcatca aataaaggca agctaacatt gattttcgga
     9361 atatagatgg ctccgatcat atgttgttcg taatattctt ttcctggatt ttggacattt
     9421 ctaaccgctt gctcaaaagg atctttgact tgtcccattc ctgggattac tgatgtatga
     9481 gcaagcgtct gatttttctt ttcatgcact gctaattgtt gctcatgttt ttcttcttta
     9541 tcgcgttcaa gctgcttttg ataattctcg atccttcttt gatccaaata attgctgaga
     9601 gcatctgcta aaaatggata tgtaaaaact gcagctccgg caagaaacat cactgccata
     9661 aataattgta ataaaagact gatttgggtt tgaggtctat tacctatttt ctttttcatt
     9721 ttcttcacct tcttatttaa aaaaactgca gcaaccttta taaaaccgat tgctgcagct
     9781 tatttttgtt gcttatactt cagacttcat tttagattta cggtaccagc tgtacgctcc
     9841 aatcatcaaa cttattccga ttagtaagaa tgccaagagc ccgttcccac cagtagcagg
     9901 aagtgacccg cgtttcatat tcggtactct ttctggccct ggattttcta ctcctacgat
     9961 ctgaatttct tcattatagc ttccataaga gatgataaat tcagtaaagg ctgcctcacc
    10021 tgttggaagt acataacctt ctggcgccat ggtctctttc atttgatagg ttccataatc
    10081 taacccttga acctcaaagt atccatttcc atctgcgaca aattctgttg cttgtccgct
    10141 tgttgcccac tcaattctat ctgctcctga ttcataaaca gctaaaggcg actccccttt
    10201 ataaaatatt gcgtattcag aacggtcttc attccacaat tcgaatcttg catctttaag
    10261 caattcactg cttgatgcat catatttttc aaactttctt ccacctgttg tgactttctc
    10321 tggcggctct actccttctt cataatcaaa ttcatcattt cgtccgattt caataaccgc
    10381 tgtgttgtta tggaaatcat ccgcttctag ttctgtggaa accttcaaat tatacgtgat
    10441 cgttaaatct cctccacgtg catctgctaa tctacctaaa gtatctactt tggctactcc
    10501 attttcttct gtcaaaatcg tcacgacaaa cccgttgctt actacttcta ctatataatc
    10561 ttgtcctttt gttaaaatcg tctcgccggc tcgcacttct atttcctgat cataataagt
    10621 tagaccaact gtaggcgtat ctgtgatttt gtaatttttg ataacagcgc ttccgttttc
    10681 aaggacagaa tcgatgaaat aaggaatagg tgctgtgatc gtgtaagaag ccgtttttcc
    10741 tctttctaga tcaatataag aaatcgtttc ttgttctcca gcttcattaa taatcgttac
    10801 ttgtctaagg tcgctttcct ctacattcat ctgtttatct gcttctctga tttcgttttt
    10861 cggatacaaa tgcacatctg tattgtatgt gtctttccat gtagaaccat cccacacgcc
    10921 atccaccata tcaggcatca tcactggcat cataacaacc attggagacg cgattctgga
    10981 aatatgagct ggcgaataag tttctaagaa aagatagact ttatctctag aagaaggtgc
    11041 ttcttccgtc acttggacgg tagagaatac cgcttctcca gcttcattcg ttgtttgttt
    11101 gtcaatactt gtcagtcgat attttaaaaa ccaactttct gtgtgccgtt tttgaatcca
    11161 ttcaatcgct tcggcagaat taagaccgtc ttctcgttcc ggtgttaaag gattatctcg
    11221 aatcaaatcg taatatactt ccgttacgtc aaacaaatca aaatcgactc ctggaatatt
    11281 ttcttcacca aaatccgtag aaaccaatcc gctattcggt cgttcttccg gaacagatga
    11341 gaaacctttt ttgtgtaatg taatcgtcac ttcacttggt ttttgtgcga cttcttcggc
    11401 tttgactagt tttccgttcc cgaaaatccc tattcccgca gtaacgagta acagtacact
    11461 cattcccgtg acaatcattt ttttattcat ttttttctcc ccgttctttt tttattaata
    11521 aaacagcacc taacaataaa agaattccta gtaaagaaat caacgttctt gcttcattcg
    11581 tttgcgggaa tacggaccat tttcctgatt gacctggatt gcttggacca ctcggctctt
    11641 tcggtttgtc cgttgtttct tttacggtct cgttataaac acgtggtgtt gcggattcat
    11701 aggcagagac tggaactttc ccggattcta attcagccat ctcctgtccg ttaactacta
    11761 catattgtgg ttggcctttt gcatccaccc aaaattcagg gatgatgacc tcgattctct
    11821 tacttgcttc atccatctcg taaccttcca caccttttaa ttcttcaaaa taataggtgc
    11881 cagaaggcaa gaaacgttgt cctgtcgtaa caaggccctc tttatccgaa atgaatttgc
    11941 ttacattttt gtcattcaaa ggatcattgt ctgctggttt gatccattga tttttcaagt
    12001 cattagcagg agccatatct aaataatatt tccccccttc tatcatctga tatagagcaa
    12061 aaacagcacc ttctaatggt tttccttttt cagttgttcc tctttgacgt ccatacttga
    12121 agaagtatgg atctcttaga taaccgacat ttttaggata gatatgaatc tcttgcagtt
    12181 cctcggttga ttctgtcggg tgataaattg gcaaaatagc agcaattggg atagctgtct
    12241 gatcgatatc aacatccaat ccaacttctg gatcaatcga ttcttcgaaa atcaaataaa
    12301 ctgcatcccg atcttggttt ttcttaggtg ctttgatacg tgcaatcccg tctcctaatc
    12361 cgccaaccgt atctttccca gttgttaccg aagtccctat ttggacaagc ctttcttctg
    12421 tgattagctg acggatattg tttctgttcg tttcagcgat ttgctggacg aattctttag
    12481 gagtcatgtt ttcagcagct tttttttcat gataataatc ggtcatgtcg taaatggcaa
    12541 atgtcgctcc atttagtggc accgtctgtg aaatgatatc tgctgtttcc cctgcttcct
    12601 cagagatagc caagccatca ttttcatggt attcaaattg atcgttataa tcgatatctc
    12661 gaatcatccg tttatgcaac acgaattcca cgacatcttc ccctgattct tctgccgaca
    12721 tcgcatgtgg aagaaggact gctgcaagcg gtagtaaaac aagtaattga agcatcaaac
    12781 acaacagctt tttcattacc ttgctccctc ctttttagat tgtctgacaa acaaaccata
    12841 ggctgctcct gcaagcgcca tgaagaatgc agcaagcagg atatagaata atcgtccgga
    12901 tcctcctgta gcaggcaacg gattttcagg atcgttcccg acactaagct gtaatctgat
    12961 tcgatttgtc tccaaaagtt catattctaa ctcttgctgt agatcaggcg tctctgcttc
    13021 ttcgtttgga taatacgaaa tctcaacttt tagtgtaccc gcttcttttc ctggaactac
    13081 ccgatcattt tctatgtcag gttcttctcg ataactaatt tctaaaataa agtaacctgg
    13141 aagttttcta tagctgtcag gtgacttcac ttccttgatc cgatagaccc cttccaacaa
    13201 gtctgaagca ttgaataggg aagaatcgtt tggatctggt gccaagcctc cctcgatgat
    13261 ttcatactct cctgcactat tttgtttctc aattgaaaat tctgcgcctt caagacgtcg
    13321 gctattcata ctgtcaattt tcaaaagttc caaatcgatt ggcgctagtt catcttctaa
    13381 ggttacttgt agtacaccat cgatgatttc atagccttcc ggcaagggag cagtttcgtc
    13441 ttcgatgacc gtatcttcaa tgataaactt accttcttca ttcagtgcaa actggaacac
    13501 ttgatcagat agccgatacc catttggtgc gacagattcc gagacctcat attcaccaat
    13561 agacagatgc agaggttggt cgtaatttaa atcgacatac ttttctactc ctacggcacg
    13621 agaatagaag tatccgatcc caggcaaacg tttcgattct tctggttcta acggattacc
    13681 agtgtatgct cgatacagcg ggaaggaaga atcccccact ttcctgatat cgaaacctgc
    13741 accatctaat gtatggcctt catggtctaa ttttctaact cggatctccc gataatcaaa
    13801 cgtattgtaa gcagtgaatg ctacccataa acgatcctct tcatctgttg tatacgtgag
    13861 atattgccaa ttttcttcac ctgtttgctt gagttggata gtccctatag cattatcgta
    13921 aagtcgcaag atccatgtgt cattttcatc aggttctttg aaaccttctg ggttctggct
    13981 ctcaatgatt ttgtattctg catagttggt agtttcttca ctatccttat aaacaaatga
    14041 atctggctct ccgattggat gaataacttt ctcaccatcc acgattacat atttcccgtc
    14101 ttcatctact gaatagaacg tgagtctccc tttctcttcc tctacttcgt tcacaccaga
    14161 aagccctttc gctactggat atccgatttc cagtccgtta ccatctgttt cataaagttc
    14221 aaactctgcg ccattgattg gcatattact gccttcaatt agtttattga tattcatgtg
    14281 gattggcttg aattcatttc gcatttccag tttgacatac aactcatcat actctgtgcc
    14341 ttctatgtta ggctcttgta caacagaaag cttgtgatat tctccttcat aataggaatt
    14401 cggatcttta ccttccggtc cgccgactct cgaaccagat gtatattcat ctacaagctc
    14461 gtagtgacct aacatctcat cttcgttggc tgcatatttt ttgatttgga attgatacgt
    14521 ctcatctact aactgataac gtggtggtcc agcgatctct ctgatccaaa atatgtcgct
    14581 gactgctcca gtttcatctc ctaaaatcgg catcttcgtt tcaaagatcg ctattccgtc
    14641 cgtggtagtt ttacttgttt cgattggttc ggcttcccca ctctctggat tttggtcata
    14701 taatgcaaat tcgactccag ccaacggctc gccattttga cccttcttgc tgacttggaa
    14761 attacggcct ttatgttcgt aacgaatgga agaagatggg aaatacatcc gtccagtagt
    14821 gatatcattc tcataatcct ccaggttctg aatataggcc atattgttca ctgtgcaaaa
    14881 atttccgtct tgagctcccg catcaagttt tacttggtac ttgatcctga ccatttcccc
    14941 ttcacctaaa gaaatcggag aaaatttata agcttggttt tcccgtccga catacgttgt
    15001 cggagtcgcc actacttctg gtggggcttg tccatgacgt tcttcatccc atatttctgg
    15061 ctcttggtac ttcatgccgt tttctcctgg atctagatgg taaaactgaa tatctgccga
    15121 tctgccagct ccaaatggtg agacattaaa accagtttca tcataaagtg tggcttgctg
    15181 gatcgttctc ttgaaggtag aagagatatc ctccaaggct gtaacaatgt cattcttgtt
    15241 gttcgcattg taatatcgcg gtgttacgcc atcttcttct aaatcagcaa tatttttcaa
    15301 tacatttcgt ccaatagcat ctagtcgttg tctcccgcta acgtttccat cgattcctaa
    15361 accaatggag aagatacttg gcgggttctc ttgatacttg tttttcagcc aatgatgata
    15421 agcaactgtg ttgatcgcag atgacttttc ttgcgaagta ggactgccat tcgtattgtt
    15481 attagaagaa ccatcaccaa cccagtgagt cgctttatta tctccttctt ttacctctcc
    15541 ataacgatag tgtacattta cttcatcttc tggacggtta aagtcagatg cataggtaac
    15601 tggatgagta aaccctgcat tagaagtatt cccagaaaac tcctcaaaat ttctgaacaa
    15661 aacgtcatta tcttcagcaa tcttatcttc catcacagtc cagttgctcc aagctccatt
    15721 agtgctcgta cgataacttg actgaatcgg tgcataactg aaggtcggtg tcccatctcc
    15781 cacaacgatt aggatttttt ctggatttct attttctccg ccattgtctt tatacaatgt
    15841 ttcatagcca tttttaagcc ctagtgtaag cggagttcct ccgattggtg tacgatttaa
    15901 tgctgtattc tcacttcccg tcaaacgatt gatatcattt gtcaatggaa agatgtccga
    15961 actgatttgc tcatggttat tgatagctgt actattatgg tgaaaattca ccataccgat
    16021 tcgaatatcc agactcgggt cagagagcag atctttactc atttcgttta ctgcctcaat
    16081 caacgcagca tttttagttt gactattggt cccagcggtt aattcactca tactcgctga
    16141 cttatctaga acaaaaacga tatcgattgg actgatttcc tttttctcgc ccccgatgac
    16201 atctagatag acattgtaaa gggttgttgc atcttcagga tgtagatcag atgctgtgct
    16261 gcttggcaga acaggttcta cccatttttt gatgtacgcc ccgttataat ccaagtaact
    16321 gttttcaaaa ttccgttcat ttccccaaag ctgaacggtt tgagctggaa cgtttctatc
    16381 ttcttcgcct gcagttgatc cattattagt agcatagtcg taatttcgcc agttcgctcc
    16441 cccgtttgta taatcactat catcgatcaa gttctctccg tcatatggcg agcctttgtc
    16501 tccttgatag cgttcattgc tttgtgtcca atttcctaac acttttgtat agtcattcgt
    16561 tgtaaacttc gggtagcgat gctgttcgtt ttcaacttct ccgctaggat agatatattc
    16621 ataggggtct tgcgtagctg ttggcccaag acgctccaaa ataccgttga ataactggcg
    16681 ttgaatgcgc tggagtgctt gaccgctggg tacgattggt tcgtccagct tttccatctc
    16741 attttcttcg ctacgttgaa tttcagcgga atcttctgta tcagtttcat tttcttgtaa
    16801 ttcttggtta tctattcttt catcaaccac cacttgaaga ggtagttacc cttcgttcac
    16861 atcggggatc ttttctgttt caaaaatcaa tgtgccggtt tctgcttctt ttgaataaac
    16921 ttttccgaca taccattctt gaccatcgat cgtctcgact tttaggtctt ctccatcttc
    16981 atcataggag gatagacctg ttccacgaac gttttttacg gtaccaatcc cggcggctgc
    17041 cgcatcgatt gctaaacgta ttctaccttc attggcactt tccttttttt caaaagccag
    17101 atgccattca agggtttctt ctttttcaat atacttccct tcaatttttg catagtcctc
    17161 atctaagaat acctcatcct cctttgtttc tgttgactca gcagctacat ccagggtcgt
    17221 catatgatag actgactgga aatatggtcc aaatagcaaa ctgacagtta ctaactgcaa
    17281 aagcttcaat tttaaccctt tcacatcctt atactccttt caaaaatatt tgtcttcttt
    17341 cacaacaatc aacaaaacaa tgcccatcta attataattt aatttaattt taattttaaa
    17401 tcaaatgata tcctttttag ttaaaaaaca ccaattatac aacatttatt attaaaatta
    17461 aattataaaa ttttataacg ttctcattta acaaaactta agttattaag acaaatgaat
    17521 aaacaactac gctttcctcg aaacaaaaaa ataaagcaca aatgcgcatt tacgcactca
    17581 tgctttattc gtacaattaa ttcagataac ggcagcgcat aggatgccaa taacacttcc
    17641 taaaatagct cctcctaaaa tgtcagtagg ataatgtaaa agtaaaaaaa tcctcgaata
    17701 agcgatcaaa caagcaaata aaaaggctaa tattcctgca actggactta attcgaacaa
    17761 cgcagctact gataaaaagg ctagcgctgt atgtcctgaa ggaaaagaag aagtcttcgg
    17821 tttacttgtg taaaggacaa gccgacgatt tttttcataa ggtcttttcc gtcttgtcgt
    17881 ttttttgata aaaagcaaac caacaaaaaa atagatcaaa ctgccgataa gaatggctag
    17941 accatattct ctagtatcag gtatcaagac taaaacagca gcaaggagca accaaataaa
    18001 accaccatta gagatattac tgataaattt caaaaaattg atttttcgac tatccgtttt
    18061 ccgttgcttg gcgaacttgt tgataatact atcatcgatt ttagcaatca aacgcaacat
    18121 gttattcctc ctttttaaga accttttctt gcgtacgatg gataaaaagc aggacttgaa
    18181 aataaaacaa gaaactgaaa cctaataaag caaaatagat tggtcctgca aaccagaatg
    18241 cgacaagaag gatcaacgtg cctgccaaat agaaaagcgc gcttttgaaa tcattaaaaa
    18301 acaagaaaaa tgcagtaatc caagaagctt ctttttgttc cagttgaagc aagattttgt
    18361 aactaaagag aagcgcgctt aatagaagca aaaacaacgt agtatacatc aatgtatagc
    18421 caattccccc accccaatag cggaaaatct gataatcgat caatagaaga agaaaataaa
    18481 cacttgctaa actatcttgc tttccataaa gagagaagtt ctcacgaaac tttttccaga
    18541 atagtgaacc gagctttttc tcttcatttt ttttgtaatg ataaatcata tacagaactg
    18601 ttcgacttgc agttcctaat gtgaaaacag gcaagacgca caggaaccat agtagctgta
    18661 aatggataag acgtggaatc cattcaatga tttctaagaa ataatcattg gcttttttac
    18721 caatcgatcg attcatcatc cttttgaacc tcctgtcaaa tccatccctt caatgaaata
    18781 acgttgtgca aaaaagaaca gcaaaatcgt cgggatcaag acaagtgttg ctcctgccat
    18841 cagataattc cattgtgtcg ttgcttggtt ctgaaaaact tgcaagccaa tctgtaacgt
    18901 gtatttttct tgatcttgga tatataacag aggacctaag aaatcattcc aagctgcgtt
    18961 gaaggaattg atcgcaatgg taatcaaggc aggtttcgtc aatggaagca tcaaatgact
    19021 ccaaatatac aaatgattcg ctccgtcgat ttcagcagct tcgatcaatt cattattgat
    19081 cgataagtaa aattgacgca tcagaaatat attgaacgca ttgccgaaga acgatggaac
    19141 gatcaggggc aaataagtac ctacccagcc gatcttggag aataatacat attgagggat
    19201 catcgttaca aaccccggga tcatcatcgt agaaagaacc aaagcaaaca tcagcttttt
    19261 cccaggaaaa tcaagcttcg caaatccata agcaataaaa gaatttgaaa ggacattacc
    19321 gatcactact agcacagtga tgaataatgt atttcttgca tagcgccaaa aaggaaaggc
    19381 ggcaatcgta tccagatagt tttcccatac gattttttct gggaaaaagg tcggaggata
    19441 acgaacgatt tcttccattg gtttcaatga agtaaacacc atccaaagca atggaatgat
    19501 caaaatgatt cctattactg tcatgaggac ataacttagt attttttttg tttgccgatt
    19561 cacactggtc tttttgaaat aatccatcat ttgccgtcac ctccagaata atagacccac
    19621 ttaggtgcaa gcttcaaatt gacaaacgtc agaaccaaca cgatcagaaa caggatcatt
    19681 gacatagcca tcgcataacc catatcaaaa gctacgaacg ccttgttcca catatgcaga
    19741 ttataaaaaa gcaaagaatt tgcaggtccg cctgttccat ttttcgtcat gacataagct
    19801 tcttgaaaaa tttggaaaga accgatcgta gaggtgatca catcgtaaaa aataatagga
    19861 gtgattaatg gcaaagtaat acttttgaac tttccccaaa cgcctgctcc atcgatttct
    19921 gctgattcat ataaagatct aggaacattt tgtaatgtag ctaagtaaag tagcattgct
    19981 cctccagaac tccatatttt catcaaaatc aacgcaggtt tcgtccattg tggatcaaac
    20041 agccaagctg gtccagggat atggaaccag cccagaaatg tgttgatcaa tcctgcagat
    20101 ggagaaagca gctgcatcca taagatgtag actgctactc ctgataagac tgccggtaaa
    20161 tagaaagctg tacggaatac actgattcct ttgatttttt gattgagtac tgtggctaaa
    20221 aacacactga aaatcgtcgt cagcggtaca ttgaagatga cgaaataaac ggtgttgtat
    20281 aacgatttcc aaaataaatc atcgtgaacg aacattcttt tgaaatttgc tagaccaatg
    20341 aaattcatct tggatgtcaa attataatcg gtgaaactac caataactga aaaaagcata
    20401 ggccctagca taaataccaa gaacccgata ataaaaggcg agataaataa ataggcccat
    20461 cttgcttctt ttttctttcg gatagataaa cgcttcaaat tttcttgcct cctctgtacc
    20521 tagacagtca aaaatggatt attgattttg cttgactaag ttttctactg ctttttgtgc
    20581 atctgccaat ccttcttttg gtgattttgt tcctaaaaga atctggtcaa tctgttcatt
    20641 cactaatgtc gtgtaatccg gagcatctaa aggaactggt gtgatcaccg tatttttaaa
    20701 gttttcgtcc gccatttgat agatcatttt tcctttatcc gttaggttgt cattattcac
    20761 taaattctca ttggctgtct tgctcgccat gatatcaaaa cttttttcgc cgaatttttc
    20821 ttgtacttct ggagaagaaa gatatttgat gaattcataa gaggcctcag gatcttttgc
    20881 tccgtatggt acttccaaga cgaatccgcc accccacgac caatggcctg aaccttcttc
    20941 tttttctggg agctgcatca cgccaaaatc aaaatcatcc ggtgcatttt ccatcaaact
    21001 agagtaataa ttgatatttt gggcacgcat ggctactaat ccggaaataa atggatcaga
    21061 tacaccagac ccaaattcgg cttctaattt attgatcgta tttttcccat aataatcttg
    21121 ccagtcttgg atccactcca aggcttccac tttattttta gtatcaatct tgactttttc
    21181 atctttgtca aaccaactag tcccgttatc tgcgtttagc gcccatacat cagcccctaa
    21241 attccataat ggataaaaac cgatgcgtgt aaattctttt ccttcttttt tatctagttt
    21301 acgtgctgtt tcttctaatt catcccaagt tgtcggtaga tcttgttcac tgattccagc
    21361 ttctttaaat aactttttat tataaaaaat gacttgtgta tctgtattga atgggatcgc
    21421 ataaggatca ccttcatatt ctactgtatc ccaaagctgc ggataaaaat ccttagaagt
    21481 gtctttttct acatatttgg agagattagt tgcttgctgt gcttctgctc tttgggcaac
    21541 ggaatttatg tcctgtacaa taacatcggg tgcatttcca gctgttattg cagataaaga
    21601 tttagtccag atgtcacccc atggctgata cttataattt acatggatct cgttttgtga
    21661 ttgattgaaa tcctcaatga tttcttcgat agcttctttt cgtgcaccgg atccccaaaa
    21721 ggaccagaaa tcaatatttt ttcttccatc acttgttttt tcagaagaat ttgctgcact
    21781 tgaactggca tcgcttgcat tacttgatcc gcatcctcct aataaaaaca atgctgaact
    21841 tgccagcaac cctgtaaaca ataatttttt catattttac ctccaaattt taatgtaacc
    21901 gatgccggtt ttaatataac gatatcattt tgttctgaaa ataacaattt ataaggtatg
    21961 attctaaaaa aattattaat gataccaata ctttatataa ttcgcgagcg ctttctttga
    22021 attttttaat ctttcgtagc agaatgagaa tgtattaaaa atagattagg aggaattttg
    22081 atgtttagac accagaaaga attgcagttt gaagcaaaac cagatcgtcc gaatccatta
    22141 atcgcgaaat atctgcagga gctgatcggc ggccaatatg gcgagatgag tgtagctatg
    22201 cagtacctgt tccaaggctg gagctgccga ggagaagaaa aatataaaga tatgctgatg
    22261 gacattgcaa cagaagaaat cggccacgtg gaaatgttgg cgacaatggt tgctcgttta
    22321 ttagagggtg cgcctgttga agatcaagaa gcagcgatgc aaaaagatcc aacaatcggt
    22381 gccattatct ctggaatgaa tccacagcac gcgatcgtag ctggcttagg acctcgtcct
    22441 gctgacagcg tgggcaatcc atggagcggt gcctatatca ttgcgagtgg caacttgtta
    22501 gcagacttta gagctaattt aaatgccgaa tcacaaggaa gacttcaagt agcacgtatt
    22561 tacgaaatga tcgatgatcg tggcgtaaaa gatatgctgt ctgttctcct tgcaagagat
    22621 agctatcatc aaaatctatg ggaatgtgca gtgaaagaat tagaagaaaa agaaggttca
    22681 atcttagtcc caagtacttt cccgcgtgac aaagaacgaa aagacattgc ttatgacttc
    22741 tataacttct cagagggaga ccaaagtagt gaaggttctt gggctagtgg caaagcactg
    22801 gatggcgaag gcgaatatca atggttgaaa gaacctaaga tcgaaggcgc tgcaccaaaa
    22861 ttagaaccag taacaccaaa aatgtatggg acacctccat tcaagaaata aatatctacc
    22921 cgtagaaaca cccgtttttt gttccacacg ctttgtgagc aaaactgact aaagtcatta
    22981 atcataacca cccttcaaaa gggtggtttt ctctagagct ataagctcaa atcaccggcc
    23041 agcgcctaaa gacgctggct ttcatatttt atgttcaagc catattgcct ttgccagttt
    23101 tgcccacctc ttaaaaggtt tatgtactac tccttagccc ttaaaaggat cgtcttactc
    23161 tcgtacactc agcttatcta acgcactatc atgtttttct tgttcttgaa tgtacttttt
    23221 gatggtcgct tcattttgtc ctacttttgt cacatagtat ccttccaccc aaaagtgtcg
    23281 atacccaaat ttatatttta gatttgcaca atctcttgat gatctcctga atattggctc
    23341 gatattgatt ataaattatt tttcttctat actttggtgt gaatacaatg tggtatttac
    23401 acatctactt tgtacgggct aaactatttc cctttattgc tccacccgca tagcaagtgg
    23461 ttttgtattt caatcgctcg gcgcgctcaa ttaggtctaa agacaataaa tctaaaaacc
    23521 cgctgcttca ctgacagaaa caacgggttt tcagaaaaaa atgaaatgaa aaagatctct
    23581 tacggcaatc tattttattt ttttgatttt ttataaatgg aaaatgcttc aagaagtcca
    23641 agaaataaag ccgtataaaa acaagaacct atgaaatctt tatttattag atattcaaca
    23701 gaaatcccga taacactagc caacaatata tttatcagaa gtgtaaaata aggatgcttt
    23761 ttatagaata gaactagtgt tgttttcata gactctcctt tcttcatatt tccaattaat
    23821 cacaaattca cggcattact agaaaaatta aaggggcgca gaagtggaaa aatactcttc
    23881 gactttccct acaaaccagg ccatcttgtg tttaataact ataccaaatc taaggtacct
    23941 ctaaatctaa attccatttg tggcggtgac ctccaatttt taactcttct atctcccatc
    24001 cagtatacat aaccttgata cttcgaccac ttatatatcg aacacacaaa tacctatcca
    24061 ttgcaggagt actacctaac ttagttgcta cttgcatcta aataacagct gaaaagatag
    24121 gacttactct tagtaaagta tctgaactat taatttttaa actatcattt ttatcctcaa
    24181 ctacatgcac atctgttgca acttcacttt ctgtctcatc cagataaatg attaaggaat
    24241 cgggaattgc aatatcttca gctgacgctg gaatagttga gctaaattag tcatcatatc
    24301 tttattataa aataaccaac agcaaaaaat acaatgaaaa acaaacttgg aactaatgta
    24361 tcattaataa atgttgaaaa attcagcaac tcattactgt atgattttag cagcccaacc
    24421 aacatatacc ctataaaagc taataagatg gttaggaatc ctttagaatt tttactcatt
    24481 catagacact tccttaaata acttttatta tagaaggtat tgtaaataat aatattgaca
    24541 aaaagtgact caaaataaaa aaaaccttac attatactgg aatgaactgt attgatagtg
    24601 tacctaaaag ctctactgac ataagatcgt gtaatcggta aagtaatttt attaattata
    24661 cgggatgtaa tcaattagag aataaactaa tcataaaagg tacttttaca ttcataattg
    24721 tcgctttgag attctacttt ggttcactat ctgacccaat tgcacatttt cgatcattac
    24781 aagtattggt gtcgttagaa caactaaata aaaactagcg gtagattttt cagaatctat
    24841 gctaatttct gtatggatgt tccagtgatg gcaaatttct cttttcattg tttttcttgt
    24901 cgcatgatat gcctttttgt gttattcagt taaactatag aaattctttc ctagacagat
    24961 cttgatccca aattttacgt ttttgagcat cgatatagtt taaaatgaca ttactcatat
    25021 ctaaagagtt tagatttttt aggactaaaa ctgtcagttg ttctttttct tctttctgtt
    25081 aaagtattgt cgcgactttt cgtatacgtt aagatatgtc gtgaaaaaac aagttttgtg
    25141 acacaaaaaa acgaatgact tgaggaaatc acctcaatca ttcgtttaaa atgctatata
    25201 ttctttagtt taagatacgg aaattaatgc catcgaccac actagtagaa tgaacgacat
    25261 ttacttggcc tttttttaat ttcgttatgt ttagcatata aaaatattat agagtttact
    25321 tacaatgctt aaaacatata ctgtataatc tgatcaattt tagccatgtc ttgcaatggt
    25381 aagttttcta tttttttgag ttttcgttcc ttaaaatcaa gagattttaa ttgtgtaata
    25441 attacttgtc cttttatatc tagctcttca ggtaatgagt aacgtgtcgg taaattcttt
    25501 atagtggaag taattggaca tatgaccgaa aacattgttt tacggttaaa ttcataacga
    25561 gagacgacta gtcctggtcg tcttttttga atttcttttc ctacggaggg atcaaaatca
    25621 atccatacaa tatcaccttt tttaggaata taaattcttt cttctgacac tataaaattt
    25681 ctctcccttc aggagttaaa tcttcccatt cgtctttctc ataatactcg gcctcttccc
    25741 caccactaaa tggatcttca atttttggaa ctaacgtaat tgttccatca tcagaataca
    25801 caacgatata ttcttggttt tctgaaggtt tctttccgtt atcagaaggt aaagttacca
    25861 ctacagaact tccttgtaat ctagattttg taacaagcat tatcatcact cccttaataa
    25921 aagtatacta tataacacta agtaacgcaa aattcccctt tgtaaactat ctagaaaatt
    25981 gttttgttta aagtatatct tattggatat aaatagaaat aaattgtagc cagttcattt
    26041 tttctttaac taaaaaaata atccaagaaa cattgaacct atggatccaa aagctaccca
    26101 aatactatag ctaacccccc gctaccttca attttgcaga taaaacgctt tgggagaaaa
    26161 tttcaaagac aacaggccat cctatcatgc ccgattataa acaaaaagct ggctattcct
    26221 tttgctctga caaatttcaa ttgggaaagt tcacgaaact agcaggtgaa gaagtttcaa
    26281 ctgttcggat caaagaatgc ccgcttcaaa tagaaacatt ggttcaacga atttcaacta
    26341 gacaagactt tgctattgta gaacgtgaga tcgtagctat ttttgtagaa gaagggattt
    26401 tacatgatcc aactcatatc aatgtggata aatggcaacc tcttatctat aaattcagag
    26461 aatatacaac tgccaaccag tcgttaactt tgaattttag attccaagaa ttcaaagagt
    26521 cataatgata aacatcgtta ggtataaata aaaaagactc gcagcacgag taaaaaacaa
    26581 atagaagcta tacattagaa aggtcgactg tgaccctata gatgcagtat atgcagctta
    26641 tgagcatttc ttctgttctc tttgtttttg ggatctgtgc tgaagtcttt ttcgtttttt
    26701 gccgctcttt ctttgaaaaa tcgattatgt tataccttct ccattactaa ttcaggcatc
    26761 tgctgagtaa tgatttttcg cgcaaaagaa atatctgtta cccaaggttc gatttgttct
    26821 tcagtcaaga caagcggcat tcggtcatgg attggtgcga ctgtgcggtt aggttcagta
    26881 gtcattatga ttgattctgc cattttttca tcctgatggc tacgataaaa accgccaata
    26941 tacactattt tttccttatt tgaaaacata aatttgtctt tttcttcatt ccactcattg
    27001 ggaaaacaca acgattttgc aaaaatggtt gatgaaaggt ctttttttct tctactgtct
    27061 ctgcacgggc attaatcatc aattgtcctt ttttaaatcc ggtaaatccc cacttcatga
    27121 tttccggagt gaggatgttt tcttcctctt ttcttaacgt cacaacaaga tttgacggaa
    27181 aaacttctcc agctgctaat tctgctgcct gcttcggttg tttcgtctgg gcttctcgat
    27241 aataattctg aaggagctct gactctagat caaaaaaata acgaccacac atcctaatcc
    27301 ctcccaatct ttttttctat catacactgc aacaagaagt tcgcaccaac aaaacgcttt
    27361 caatttttgt agaactaaaa aagttgtgac aagtgacaaa ctctccagtg aatggtattc
    27421 tcctgccaac tcctcggtca caagtcacaa tattcaacaa acatgagaag ctgctttttg
    27481 aaattgttcc ttgtgactcg gagtgaaacg gcaggcttac gacctctggg taaacggtgt
    27541 tcaaaagcca gtttctcggt attaagccaa atttatgcaa aaatgtagaa agctattttc
    27601 acaaaatttt tcttaatact cgaaactaag cgactttttc acaacctctt ccttaaacgg
    27661 tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat gagcagctat
    27721 ttttatttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc tctccactaa
    27781 acggtgttca atcagctaac cttcggtatt agctcaaaaa acggcaaaat atgaggaact
    27841 attttgccgt ttgtttctct aatactcagg tcaaagcgct gatttcacaa cctctaatac
    27901 acggtgttcc agaagtagct tcttcgaaaa ataagccgaa atttcacaaa aatttgagaa
    27961 gcaattttcg taaattcctt cttatttctt gaagctgacc acttctgtca caacctctaa
    28021 ttattaaaga accttttgcg aagttaacaa tctttctttg atcaattgaa aattctgcct
    28081 aagtagtgat agatcctgtg tgactttcaa caataagata cttccctgga tttcagcaat
    28141 caacgctttg gcttgacggt ctgcttcttc atcggacagt ttttcttcag aaagtgccag
    28201 gatattttgt ttcgtatact tgacccattg attgactaat tctagtagca acagacggta
    28261 ttcttcatcc actgtactca actcaataat caaattacct acaggacagc catgataagt
    28321 gatctgtgtc tcatgatcag cgaaaatcca gtccaacatt tcttctaatg cttcttctgg
    28381 ctgttttcca gcatttaaga tgtcttcgaa caattctgtc tgccatacgt ccatatgcgc
    28441 atggatcacc gctagacaaa cttctttttt tgaagaaaag taataataaa attgaccttt
    28501 tcctgtatca gaagctgcta gaatatctcg gattgacgtt tcatgatagc cttttttata
    28561 aataagatct ttggtcgctt ccaagatctt ttcctttgtt ttcaatgata ttctcctttt
    28621 tcatttctca tagtcctata ttatacagta aattcatcat tttttcttct taatcgttta
    28681 aaaaagactg tgccaaatta tctgacacag ccctcactat aaaactgttc tcatatagct
    28741 agatgttcat tgattcaaga actgcgagga caaaagcaat tcctatctta tgatagttgc
    28801 tctaatactt cctctgttgt catcacttga tctgcaataa agccaaagtt cgtcaacgct
    28861 gcatccattg cttcttggcc aggagcacca attgcatctg tcgctaccac aacattgaat
    28921 ccactctcta ccaattcacg catatgggaa tcgctacaca agtttccgtt cattccacca
    28981 agaattactg tgtcgattcc attttttctc aattggagcg ccaaatcatt gctttctggt
    29041 ccaaagattt tatgaggaga gctgatgatc gtattttcat ccaaataagg tttcaattct
    29101 tcgataaaat cggctcctga accttcttcc actgattcat attgactttt tctagcaaac
    29161 atctgctgct caagcatcat atgttctcct gcaccgccaa attgccattt atggtcatgt
    29221 gggtaaaaat aatgaggaga aataaagagt ttgtatcctt tttcttttgc ttgttttacc
    29281 atttcaatca tattttcgat cgtattgtat ttttctaaga tatcttttgt caaaccaaag
    29341 ccaccgcctg ctggtttcaa gaactcgact tgcgggtcag tgagaactac tgctgtattt
    29401 ttattattga acatggtgga ttctccattc gttatttatt ttaatacatc atttagagct
    29461 tcactcattg tcggatgaga atagatttga tctctcaata acgtataagg aagttttcca
    29521 ttcatagcta gcgaaatcaa gttgatgact tcatgagaat cttccgcata gatacttgcc
    29581 cctagaatca agtcagtttc agggtcgact aaaactttga atacaccttt aggatcttct
    29641 aatacttgtg ctttagggac accgcttgtc atatacttga ataatttgta attgacgcct
    29701 tgtgctttgg cttgtttttc tgttaaacct acattggata aagtcggagt gataaataca
    29761 ctgtaaggca cagctttccg gttattcgtt gttcgtttat tctcgccctt caactgatcc
    29821 ataatgattc gataatcatc tagagagata taagtgaact gcaatccgcc tttgacgtct
    29881 ccaatcgccc aaatgttgtc tgcatctgta cgaaggtatt catccacagc gattgctccg
    29941 cgatctgtta gtttaacatc tgtattttct aatccaagtg atgctgtact tggttttctt
    30001 ccagttgcag ccaaaacttt tgacgcttgg attgttactt cttggccatc ttctgtaaag
    30061 gtgacggcag ctgttgattc ttggtctgct acttgatcta cagatacacc tagatggaat
    30121 tcgattcccg catttgtcat gtcttctaaa atcatttgcg cgatatcttc atcttcacgt
    30181 ggaagaaatt cagaatgggc atcaagaacg acaactttag atccgtattc attgaacatt
    30241 gatgcaaatt ccaagccaat atatccagcc ccgatgatca ctaatttttc cggtaattgt
    30301 tcctgatcca tcgcttgcgt agaatcaatc aagtagcgac ttgtattcaa tcctttgatt
    30361 ggtaaaatga ttggttcaga accagtattg atgaaaatcc gttcgccttc aacaatcact
    30421 ttttcaccat tattcgtcac ttcgatttga tggttagaaa gaaaacgtgc tgtaccgtcc
    30481 atcactgtcc cagttgcctc atcgctgatc atatgataat ttttggcgcg aagcatgccc
    30541 gtcaattttt ctttccgagc aacagcctct gtaaagtcga ttcctctttc tccattgaaa
    30601 atcaatgatt tagaaggaat acagccgatg ttgatacatg ttccgccata catacgtgtt
    30661 gacttttcaa cgactaaaac cgattcacct tttgaagcta acgccttcgc taaagtctta
    30721 ccgccctttc caaaaccgat cacaatattt tgatattttt ccatcatttt tccctcgctt
    30781 cttttttacc taccgattgg tacaaaaata tgataaccga taattgtcta ttctccaaat
    30841 catctgc
//
LOCUS       DAIGTA010000033        29682 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.033, whole genome shotgun sequence.
ACCESSION   DAIGTA010000033 DAIGTA010000000
VERSION     DAIGTA010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.033"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..116
                     /locus_tag="NOB43_001579"
     CDS             <1..116
                     /locus_tag="NOB43_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0982440.1"
                     /translation="LSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            308..928
                     /locus_tag="NOB43_001580"
     CDS             308..928
                     /locus_tag="NOB43_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCI0982441.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(1020..2186)
                     /locus_tag="NOB43_001581"
     CDS             complement(1020..2186)
                     /locus_tag="NOB43_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0982442.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(2198..2551)
                     /locus_tag="NOB43_001582"
     CDS             complement(2198..2551)
                     /locus_tag="NOB43_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI0982443.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            2679..3701
                     /locus_tag="NOB43_001583"
     CDS             2679..3701
                     /locus_tag="NOB43_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HCI0982444.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            3720..3881
                     /locus_tag="NOB43_001584"
     CDS             3720..3881
                     /locus_tag="NOB43_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982445.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(4140..4574)
                     /locus_tag="NOB43_001585"
     CDS             complement(4140..4574)
                     /locus_tag="NOB43_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982446.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(4684..6543)
                     /locus_tag="NOB43_001586"
     CDS             complement(4684..6543)
                     /locus_tag="NOB43_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0982447.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(6661..7820)
                     /locus_tag="NOB43_001587"
                     /pseudo
     CDS             complement(6661..7820)
                     /locus_tag="NOB43_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(8127..9551)
                     /gene="araA"
                     /locus_tag="NOB43_001588"
     CDS             complement(8127..9551)
                     /gene="araA"
                     /locus_tag="NOB43_001588"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCI0982448.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(9567..10265)
                     /locus_tag="NOB43_001589"
     CDS             complement(9567..10265)
                     /locus_tag="NOB43_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI0982449.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(10222..11883)
                     /locus_tag="NOB43_001590"
     CDS             complement(10222..11883)
                     /locus_tag="NOB43_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HCI0982450.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            12101..13501
                     /locus_tag="NOB43_001591"
     CDS             12101..13501
                     /locus_tag="NOB43_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HCI0982451.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(13753..14832)
                     /locus_tag="NOB43_001592"
     CDS             complement(13753..14832)
                     /locus_tag="NOB43_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0982452.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(14918..15877)
                     /locus_tag="NOB43_001593"
     CDS             complement(14918..15877)
                     /locus_tag="NOB43_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI0982453.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(15889..17400)
                     /locus_tag="NOB43_001594"
     CDS             complement(15889..17400)
                     /locus_tag="NOB43_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI0982454.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(17422..17985)
                     /locus_tag="NOB43_001595"
     CDS             complement(17422..17985)
                     /locus_tag="NOB43_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCI0982455.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(17991..18854)
                     /locus_tag="NOB43_001596"
     CDS             complement(17991..18854)
                     /locus_tag="NOB43_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0982456.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(18868..19764)
                     /locus_tag="NOB43_001597"
     CDS             complement(18868..19764)
                     /locus_tag="NOB43_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0982457.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(19939..21228)
                     /locus_tag="NOB43_001598"
     CDS             complement(19939..21228)
                     /locus_tag="NOB43_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0982458.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(21200..22717)
                     /locus_tag="NOB43_001599"
     CDS             complement(21200..22717)
                     /locus_tag="NOB43_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI0982459.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            22915..23805
                     /locus_tag="NOB43_001600"
     CDS             22915..23805
                     /locus_tag="NOB43_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HCI0982460.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(23878..24702)
                     /gene="nadE"
                     /locus_tag="NOB43_001601"
     CDS             complement(23878..24702)
                     /gene="nadE"
                     /locus_tag="NOB43_001601"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCI0982461.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(24714..26186)
                     /locus_tag="NOB43_001602"
     CDS             complement(24714..26186)
                     /locus_tag="NOB43_001602"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCI0982462.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(26823..27185)
                     /locus_tag="NOB43_001603"
     CDS             complement(26823..27185)
                     /locus_tag="NOB43_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI0982463.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            27408..28160
                     /locus_tag="NOB43_001604"
     CDS             27408..28160
                     /locus_tag="NOB43_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0982464.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(28300..29223)
                     /locus_tag="NOB43_001605"
     CDS             complement(28300..29223)
                     /locus_tag="NOB43_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0982465.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFSFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(29238..29510)
                     /locus_tag="NOB43_001606"
     CDS             complement(29238..29510)
                     /locus_tag="NOB43_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982466.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8803 a         6160 c         5084 g         9635 t
ORIGIN      
        1 ttctaagcta tacaggcagg cgatcagaag cattagccga tcaacttact gctaatggtt
       61 ttcgtgctgt ttatatcatt ggtgggatgg aagctcttca gtcgagtgtt gcttgaatat
      121 tgcttgttag attcaaaaga ggctgtgaca aaaaatcgtg tcacagcctc ttttataccc
      181 tgtctttttt tagttattta ttcttcaacc ttatcaatat gacttgatag ccttttcttt
      241 ttcgagtaaa ctgattttgt tagtcatagt tataacaatc atagcaataa aaggagaagg
      301 taagcatatg gcatctgttt tagtagtcaa aggtcatccc ctaactgcag aagaatcgcg
      361 cacagttaag gcattgacgt cttttttaac aagttataaa gaaaatcatc cagatgatga
      421 agtgactgtt ttggaacttt atcgcgatga tattccggaa atcgatgaag aattattatc
      481 aggttgggaa gcattacgtg ctggtgcaga attcacttcc ttatcagaaa gtcaacaaca
      541 aaaaattgct cgtttcaatg aattgactga tcagttcctt gctgctgata aaatcgttat
      601 cgcaaacgcc ttatggaatc taaatatccc aacaaaatta aaagcttggt tcgataccgt
      661 caatgtagct ggaaaaacgt tccgctatac agaaaacggg ccagaaggat tagtgacagg
      721 taaaaaagca ctgcacatcc aatctaatgg cggtgtatac aacggacaag actttgcctc
      781 tcaatatgta aaaggtattt taaactttgt aggcatcgat caagtagatc agctattcat
      841 cgaaggaatc gattatgacc ctgaccgtgc agatgagttg atgcaaaatg cattagataa
      901 agctgctgct ttaggtaaat cattttaaaa attgagataa atgcatacaa aagagacaga
      961 ggaaaaaatc ttcaaagcag catttgtgcc ttggatattt tcccatctgt ctctttttgt
     1021 tattctttct gctttttcaa cggattttct tcataaagag aagagattgt tgtgtaccat
     1081 tcaaaaacat gagtaatcac tactttagct gctgcataaa caggaatccc caagatcaca
     1141 ccgatgattc cgaacaattt cccagaagtc agcagaacta ataaaatcgt tactggatgg
     1201 attgctaact gattccctag tactaatgga gagatcaagc gtccttctat tgtctgctct
     1261 actgcaaaaa cgatcagtac tttgatgatc atgaatggac ctgctacaat ggctaaaaag
     1321 atagccggaa tcatcgctaa aaatgatcct aagtaaggga tcaggtttaa aaaacccgca
     1381 ataatcccca acgtgacagc atactctaaa ccaatgaccg caaaaccaat cataaacatg
     1441 attgccacag caaaagccac agttagttgt cctcttatat aagaagaaac ttgactattc
     1501 atttcactca gcacattcaa cgtcggtttt tgcatgcgtg tcggtaaaaa tttgacaaaa
     1561 taaggtgcta attgtttacc gtctttcaat agataaaata agataaacgg catcgtcagc
     1621 agagccacta aaatagtcgc taccgcgccg acaaaacttc caagactctg aactgtactc
     1681 ttagatatat cttggatcat atcgcctgcc gaattcatga acttatcacc tgctgtttcc
     1741 aactgttcgc gaaattggtt gaacagcggg tcccgcaaaa tctcggttaa tttattatca
     1801 atcgtatcta catattgagg gaagttactg atgaagctca ctgtttgttc ctgaatctta
     1861 gggatgatca ctacgctccc ccatgcgatt agtgcaacaa ccaaaacaaa cagcccaatg
     1921 atactgtaaa gccttggtac ttttcgcttt tcaaagtaat caactaccgg attcatcaag
     1981 taatacaaga ttcctgctaa aatgataggc agacctacga ttgctaaaaa ttgccagatt
     2041 ggtgcaaaca aatatgaaac ttttgtaaat aaaaagacga tcagcaatat taacaataca
     2101 acaagtaagg ctgtgactac ttgattattt aaaaaccagc gccaaaacca cgataccggt
     2161 ctgttcttct tattttttcc ttccataatt cctcctgtta gttataaaaa atttggcttc
     2221 ccaaaccaat agcaggcagt ctatgcggat gaagatagat tccatttgca atttgtcctt
     2281 cttctggaca agcatcaaaa atcaatgata cgtgagctac tgtctttaaa ttcccattgg
     2341 ccatcggacc gacataatcg atcgtatata cctgatcatc aaaagcaatt gttccgcctg
     2401 ctttcaaaga aaaaggttcg tcttttgata cttcttgaat caccgaatat tttcgtaagg
     2461 cagctgttgc tgttttatcg aacaaaatca gcatgggttc ttccttgttt attgcttctg
     2521 tcccaatttc tgtaatcttt gcctgaatca ttgcactctc tcctttaatt gctttcaaaa
     2581 acagtataac acattctcat tctttagccg tgtggaataa ttatgtgata gaataaaaac
     2641 gaaaactatt tcattacaat taggaggaat cagctcatat gatcgaaaag ataattttag
     2701 gaacctatac gcgtcgcgaa agtaaaggaa tctatacgat cgaccttgat acagaaaaag
     2761 aagaattagc caacctttca ttagctgttg aagaaaatag ccctacctat gtagcaaaaa
     2821 gtaaagctgg caatctttac acagttacta gtgtggatgg attaggtggt gccggtgcgt
     2881 acgataagga ttttcatttt ttgaatgcgg taacagagtc tggcgctcct ttgtgttatg
     2941 tagcggttga tgaagcacgt caattactat acggggcgaa ctatcataaa ggtgaagtaa
     3001 atgtctacca tatattagga gatggcgaac tgaaagcagc agattcaata ttccatcaag
     3061 aagcgacagg tcctcataaa aaccaagatc atgcgcatgt ccactatacg gatctgactc
     3121 ctgaccaacg attagtcgta tgtgatcttg gtacagatcg tgtgtatact tatgatgtgt
     3181 ccgaaaacgg caaattgaat cttgtaacta ccttcactgc agagccagga acaggccctc
     3241 gccatcttgt ctttcatcca aatggacaat tcgcttattt atttggtgaa ttagacagca
     3301 cagtccgcgt gctttcttat aataaagaaa caggtgcttt tgaagaatta cagaaaatat
     3361 cgaccttgcc agaagaattc gacggtgaaa atggaggggc agctatccgc atttcaaatg
     3421 atggcaagtt cctttatgct tctaaccgag gacataactc gattgctgta ttcgcagttt
     3481 ttgaagatgg ttcccacatt caaaacaagc aaatcatctc aacagaaggg gattttcccc
     3541 gcgatttcgc actagatcca agcaataatt ttgtcgtgtg tgccaatcag aacaccgata
     3601 atctgacatt atatcgccgt catcctgaaa caggattact ggaattactg aaaaaagatg
     3661 tctatgtacc agaatgtgtc tgtgtttatt ttgatcgtta gtaagaaaag gagaatgaaa
     3721 tgaatcagca agacgtatta gacagactac gggaagaact aaatattcct ttctttgatg
     3781 ggaaaatcga agataaagag tatagcgaag aggaatatca gaaactcaaa gccgatttac
     3841 agaactactt tgaacaatat gtacagaatg tagaaaacta atcagctttc catactatct
     3901 gaaaagaaca tcaggacaag acttttccgt ctatcctgat gttcttttct acaaataaaa
     3961 aaccgccgag atggttagac tcgacggaaa aggagtattt actcgatttt gagtaagtac
     4021 aaggttgttg ttggttatag gtatgtcatt atcataaagg attttgatca ctctatcata
     4081 aaggtaatat tacatttata ttagataact ctagttttta ttgttatcaa agatttcttt
     4141 tattttttca acaacaaatt agtcattttt tggatggcag ctgtcaattg gtctgtcgct
     4201 tggtcttgtt ttgcttcaga tgtattgaat agatcttcat ctacccctga ttcaagatcg
     4261 atactttgga tcatttcttc acagcctgct acatatgaaa gataagcttt ttcaaaattt
     4321 ttatgaatgc ccattgcttt tgctggtgga cgcaaagtac tgactttcat aagcattgcc
     4381 cgatattttt ttgttccttc ttcaaataac aggatgatct cttcaagagt cgatttgtcc
     4441 agttcacttg tttttccttc atcaattgcg tttctgatca cttcatattt cggatgcatt
     4501 ccttctccga ttgcttctgt ttccttgacg atttgatcga tggactgcac ataatagcca
     4561 atattcggta acatgttcgt tttcctactt tctccattgt tgttattatt tattctactt
     4621 gtttttatcc tcaaatgaca agtacttgaa aaaatttaat ggtttctata cagctcgcca
     4681 ttcttattcg tgctcaaaga aaccatctgc taaactatat tgtttccctg cgacaatgtc
     4741 atattggatc aattgatatt cgtcgtaaat ctcttgttgc gagcgattga attgcgcttc
     4801 tttataccac tgtccgtttt gatagtacag ttctcgttca aacgccggaa gttcctgttc
     4861 taatgataaa agcagctgat aaaagccatt tgttgtctga ttcgtctgtt ccattagatt
     4921 cgctgcaaaa taaaacggac tggtgattgc atcgtgagtc gtttgctttt ctaattctcc
     4981 tttactgtcg aacataagaa attgtgtttc atgcaatgtt tgtttgtcat tttttgcttg
     5041 gatcgtatct gaatagatcc ctggaagatg atccccccaa aaaacaacta aagtccttct
     5101 agaaagattc ttcaattctt ccgtgaactg cttcagtgcc gtgctgctat aggaaatatc
     5161 ttgcagataa ttctctaagt caagtgtccc acttccatct gaagtttttg caggatagtc
     5221 tagattatca tactttccat cgtagggcat atgtgtctgc atcgtgacta aatgaatgaa
     5281 ctgaggtgtt ttttcttcct tgagaagtgt cattacttct ttgtaagctg actcatcaga
     5341 aatatatgga ttattctcta tcgtatccgt ataggtcatc gtacgctcgc tgatgaactg
     5401 gtcaaatcct aatgtctgat aaacatcctc tcttttatac atcgaagtat tgtatggatg
     5461 gatcgctgtc gtctggtatg attgtgcgtt taacgctgaa acgatagaag gaagctgatc
     5521 catttttggt acaagcatcg tgtaaggggt ggtgagttgc gcattaaata acgccataga
     5581 aaaaccagtc aatgcttcaa attcgatatt tgctgttcca ccgccatagt tttgagaaag
     5641 catattgcca ctatatgttt gatcagctac ttcataataa tctgccaatg gctcaccaga
     5701 tacttctacg ccgtttaatc gactaggatc tgagaaactt tcactcatca cgaacacgat
     5761 gttcggcgac tcttcctcta cagttttatt tttttcatcg gctagcttct ggtatttttc
     5821 agtgatttct ttgatctttt ctttcgaata tccttcaggt tcatccattg gttctacctt
     5881 cagattgtac aaaaacccac cgataaaacc agtgttatag tagttcattt tctggctgta
     5941 aggtatccat agtgccgttt tattatatgc ttttcgcaac aaattatcgg gattgttgaa
     6001 attactgata taccctagca gtccaattgc cacaagcagt gtcgttaatc ggatcaattg
     6061 gaatcgcctt ccttttttca ggcttcgaaa catgtaccag caaaacaatc ctatcacggt
     6121 tcctgcggca gctaagatca ctgtaaacag catagtgccg gtcatatctt tcagcaatcc
     6181 gatttcagtg atcatcttca aatcgtctgg ataaatcggt tcttgccgat aactcatttt
     6241 catataattt gcaaaaccta atacaccgat ggctacgaca tacgtaaggg aacctaaagg
     6301 gacagatcct gctagtgcaa tcagaaaaat aagaataatc agcaagacga gacaggctaa
     6361 gaagaatttt tccgtatgcc aagaaaaagc aaatttcaac gcaaggtcta cggatagatc
     6421 attttgacac cactgcaaaa ataaattact aaaaacaaca agaaaaaaga tactgatgat
     6481 tgctgctgtt ccttttaaaa tctttttctg tttggtcgaa agtctgctta tatatctttt
     6541 caaatgcttg ctccttcatt tctatcaata aaagaatgtt gcttctctta ttttagttgt
     6601 acgaaattcg aaagtaaaga acggaaagaa gaattaatga aatccaaata ttctctttct
     6661 ttatggcctt tctggtttct ttaataagcg gacctttcgt actccagaaa ttttttctag
     6721 ctgttgtttc acttgattga gctgttcaaa atcagtactg tctatgtcaa tcaatatgta
     6781 gacatgctca ttcttatggt tacgcgatat atctgcgatc gctagctcgt tctcattcag
     6841 cagagaaaat atctctgcta atatattggt tttcttttga taaaatatag tgaatcgaaa
     6901 cggcgcttgg aaaaacattc gtgcggatgg ataattgacc gcttctctaa ccgtaccgaa
     6961 caaaagataa tcttttaagg cttcaactgc caaacgtccg ctgtctgcca aagcttcctg
     7021 agtcgatccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
     7081 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
     7141 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
     7201 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
     7261 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
     7321 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
     7381 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
     7441 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
     7501 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
     7561 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
     7621 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
     7681 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
     7741 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
     7801 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
     7861 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
     7921 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
     7981 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
     8041 agactaaatt tcaaaaaagt tgaaaagcaa atatcgtcaa tctcttctta tttcttaaaa
     8101 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
     8161 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
     8221 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
     8281 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
     8341 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
     8401 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
     8461 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
     8521 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
     8581 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
     8641 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
     8701 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
     8761 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
     8821 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
     8881 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
     8941 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
     9001 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
     9061 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
     9121 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
     9181 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
     9241 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
     9301 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
     9361 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
     9421 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
     9481 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
     9541 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
     9601 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
     9661 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
     9721 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
     9781 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
     9841 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
     9901 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
     9961 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    10021 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    10081 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    10141 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    10201 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    10261 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    10321 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    10381 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    10441 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    10501 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    10561 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    10621 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    10681 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    10741 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    10801 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    10861 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    10921 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    10981 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    11041 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    11101 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    11161 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    11221 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    11281 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    11341 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    11401 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    11461 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    11521 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    11581 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    11641 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    11701 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    11761 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    11821 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    11881 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    11941 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    12001 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    12061 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    12121 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    12181 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    12241 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    12301 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    12361 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    12421 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    12481 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    12541 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    12601 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    12661 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    12721 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    12781 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    12841 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    12901 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    12961 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    13021 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    13081 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    13141 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    13201 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    13261 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    13321 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    13381 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    13441 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    13501 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    13561 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    13621 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    13681 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    13741 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    13801 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    13861 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    13921 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    13981 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    14041 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    14101 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    14161 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    14221 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    14281 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    14341 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    14401 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    14461 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    14521 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    14581 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    14641 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    14701 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    14761 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    14821 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    14881 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    14941 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    15001 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    15061 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    15121 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    15181 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    15241 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    15301 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    15361 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    15421 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    15481 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    15541 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    15601 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    15661 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    15721 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    15781 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    15841 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    15901 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    15961 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    16021 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    16081 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    16141 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    16201 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    16261 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    16321 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    16381 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    16441 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    16501 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    16561 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    16621 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    16681 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    16741 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    16801 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    16861 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    16921 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    16981 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    17041 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    17101 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    17161 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    17221 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    17281 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    17341 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    17401 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    17461 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    17521 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    17581 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    17641 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    17701 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    17761 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    17821 tcctgatccc tcacctttcc attgcgccat tacataaaaa acagcacatg tagcaggcac
    17881 gatagtaata acaggcaaac acacgattac ccagagaata cctaataaga tgtaatcaga
    17941 aaccacaatc aactgtccat aaagtttagt ctcaactatt ttcatcttcc tcactctttc
    18001 attccagaca tagctgttcc ttgaacaaaa tatttctgtg caaaaatata aaccactagt
    18061 aatggcagca ttgaaataac cgttccagcc attacaggtc cataaaaaga aatgttctgc
    18121 cctgtaaata aagctaaccc tgctggtaaa gttctcattt ttgaactact tgtcaatatc
    18181 aatggataaa gcaagtcatt ccaactattc atcagcgtga aaatccctaa tgataaaaga
    18241 gtaggtttgc tcaatggcaa catgattttc aaaaaaatat taaactcact taatccatca
    18301 atgcgtgctg cctcttccaa agaatctggt aaagtaataa aaaaggaacg catcatgaag
    18361 ataccaaatg cagttgtcat acgaggaatg atcaaacctg cataagtatc aagcatgcca
    18421 agcaaattga cttcaataaa tagaggaatc atgaagactt ggaatgggat catcattgtc
    18481 agcaaaacga aatagaacaa aactgatttt cctttgaaac gcatacgagc aaatgcatac
    18541 cccgcaagag aatcaaagaa tacagaagtg atcactgtcc ctccagcaaa aatcactgta
    18601 tttttgatgt aatctaataa agggatcgtt gtccaaacct taatatagtt atctagggta
    18661 tagctatctg caaatattct aggcggaaat gagataatgt ctttttcgtg tttaaaagaa
    18721 gaaataatca gccacaaaaa aggaaacgca ataaccaaca atataactag catactaatc
    18781 gttcgaatga tttttttacc actaactgct tttcgactat tcacagtaac tgtaatcgag
    18841 ctttctggtg ccatacaggt ttccctccta tttcatttgt ttttctttcc gtgacatgta
    18901 cacattagtg gagatagcta tagttgcaac aatgataaac aaaaccgaag acagtgctga
    18961 tgcatagccc aattcataag gtgctgtaaa tcctcgactg taaatatatt gaacagctgt
    19021 ttctgtctta aattgtgggc caccagcggt tgcaacatat acttggtcaa acacttgcat
    19081 cgaaccaatc agattcgtta aaatacaaaa acctaaggag ggaacgatct gaggtagcgt
    19141 aatgttaaaa aactgctgtc gatttgttgc accatccatt tgagcagatt catacaaaga
    19201 gggagagatt ccctgaatag cagtcaagag aatcgtcata gtaacaccaa aattcttcca
    19261 aacagtcatg atggctaccg tcggcatagc aagggttgga tcgcgaaaaa attgagggat
    19321 cggcaagccg acttgtgaaa acaagtaagg aatcgcccct acattcggat caagcaacat
    19381 agaaaaaata atcgcaattg acgtcaatga acaaataact ggaatgtaaa atgtcgaacg
    19441 acaaaaacga ttgaatctgg tatttttaga taatgctact gctgctaata aaccaacgat
    19501 aatttgtgtt ggcgtttcga gtacggtgaa atataaagaa tgaatcaacg aattaactgc
    19561 tcgttcatca ctaaatatac gtgtgaaatt ttcaaaactt acaaaatttc ttgatgtaaa
    19621 gaaaatattc aaatctgtaa aactaatagc aaatgttcct aaaagcggta tgacagtaaa
    19681 taataataaa actaaaaaag atggagttaa aaacaaatac gcagcacgat caggacgatt
    19741 ccaatatttg gtgaatccgt tcatatagtc cacctcatct ttcattttga taaaatatac
    19801 aatcttggtt taaacgaatc tgaataagat atccgaacaa tcgctgtgat ttttgcaata
    19861 acacctatct gcaaatacta ggtcgatcat tcagatatct gtatcttgcc aacagtctat
    19921 cctgtataaa gttctgtact atttttgcag taattgattg atggcatcat ctgcatcgtt
    19981 catgagtgtc tcaggatctt ctcctgctaa taatttttca atcagtggat tgatgatatc
    20041 gttattgatc gcagagattt gggtaaaacc tggtaaatat ggctctgcat agtccatttg
    20101 tttcgataat tcagatacaa taggatcatt ttttacttct tcatcttttg ctactgaatc
    20161 caagtaggca ggaaaaccat tttcgatact ccatttttta ccaatttcag ttgtattcca
    20221 atatttcaaa aactcataga cagcttcttt tttattatta tctgtacttg ccggaatggc
    20281 atatcctacg ccatctaaaa tagctgtttt tttgtctgaa tcactccctt gtggtaaggt
    20341 agtcacatta taatcaatct cgtttgcttt caatccgtta tttaaccatg gcccattgat
    20401 ttcaatggct agttgaccag cattcattaa attgtccatt tcggcgccag aaatcgattc
    20461 tggaccagtc ttgtctacat ggatcatttt ttggatcgct tttaacgttt taaggttctc
    20521 aggagacgca aattcagact tagtataatc atcgttcact aatttaccgc catttgctaa
    20581 catccagtta tataacggtg cagttccatc cttattgaag acaaaacctg atacattttt
    20641 actactatca gttaattttg gtgccatttc tgtcaattct tcccaagtag taggtggttg
    20701 ttcagtatct aatccagctt gtttaaacaa atcattattc caatacatat acatgccttg
    20761 tacctgcatg gggacaaaat actgtttacc ttctacttca cctaattcaa tagccgtttc
    20821 tttaaaatca gatttatcta ctccatcata ttcccagaaa tcgtctaatg gttgtaccgc
    20881 tccgttttct acatactgtg caaaatctgg ataatttaat gcaataaagt caggtgcttt
    20941 tttagaagaa atcgctgtag gaagtttttc attcaaattg gcccaagtca tgatatccat
    21001 ttcaattttg atgtttttat catttgtttt attaaattca ttaacgattt cttgcaatat
    21061 ttcaccatca gatgcagtaa acccattcca aaaagtcaaa gtcacttctt tatcagaatc
    21121 agattctgct gaacttccgc caccgcaagc tcctaaaata cctgttgcag ctaccaacaa
    21181 agagccaatt aaccattttt tacctttcat tttttgttcc tccttcatct gataaacgac
    21241 atctgaccac attccaagat agcggtttca ataaacaatt gattttccca tcttcagctt
    21301 ttacatttgt tgaatgactt ggttttactt gttcactttt aggaagatta gttgcttttg
    21361 tatcaaatcc actcatttca gaaaaatcaa tcactccctc taatgataat tcagacaagt
    21421 gaacagttag attcatttct tcttctccac ggttaactgc aaatatgaca agttctttgt
    21481 catttattac ggctatactt tctaaatacg gcacttcttc aaaatcttcc gtcgcatagt
    21541 ttgctgaacg aatttgtggg cttaacacct ctccttgtcc atacacagca gcttgcataa
    21601 atggataata gatcgtctgt ctccaagctt ctccgtttgt ttctgtcctg attggtgcaa
    21661 taacatttac caattgagca agacaagcaa tctttactct atctgcatgt ttcaataaag
    21721 tgattaatag acagcctaat agtaatgcat cttcaaaatt atagttatct tctagtaaag
    21781 gaggagcaat ctgccaaggc gctgcttgct catcttgttc cgctgaatga taccaaatat
    21841 tccattcatc aaaggacagg ttgatctgct tcttactatg tttcttcgcc ttgactgtat
    21901 cgcacatcgc tgtcacttca gaaatgaacc gatccatgtc taaggaacgt gcaagataat
    21961 gagaaagatc atttttttgg ttgccataat attgatgcag agacaaataa tctatttgat
    22021 cgtacgcttg atcaagaact gttaactccc aatcaccaaa tgtaggcatt tgccgattcg
    22081 aacttccgca taaaaccacc tcaattgaat catctacgag tttcatcgcc ttagccgttt
    22141 cctctgctaa ccgtccatat tcttccgctg ttttatgtcc aatctgccaa ggaccgtcca
    22201 tttcattccc taaacaccat gtcttaattc caaaagggct ctcttgacca ttcgaacgcc
    22261 ttaaatcact ccaataagtt cctttaggaa aattacaata ttcgactaaa ttacgagctg
    22321 catctactcc acgagtaccc agattgacag ccatattgat ttcggccccc acatgctgac
    22381 accagttata aaattcatga atcccaactt cattcgtttc aattgtccgc caagctaaat
    22441 ccaaccttct aggtctattt gctatgggcc caatactgtc ttcccaacga aatcctgaca
    22501 caaaatttcc accaggatat ctaatcatgg gaatgttcaa ttcttttacc aagtgaatga
    22561 cgtcttggcg aaatccactt ttattagctg atggatgatc tggctgataa atcccttcat
    22621 atactgctcg tcccatatgt tcaataaatg aactgtacaa ccgcggatca actttgccta
    22681 cacgcttgac actactaatc aacattgtgg cttccataac tgacctcctt taatttatac
    22741 atgaataata cacctcgttg aaagcgttgt caataatata aatgttaaac ttacttattt
    22801 tttatcgatt ttaattaacc aaaatattaa taatgattaa aacaaataat ttaatataac
    22861 ttttattaac aaatatgtta atatataaga aaaacctttt aagaggtgat atatatgcaa
    22921 ctacaaataa acgaagaatc cttaccggta tatgaagcat tagctagtaa aacaaggatc
    22981 aagatcatcc agctactttc caaaaaaaag atgaatgtca aagatttggc aaaagaactt
    23041 ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc tagaggaagc aaacatcatc
    23101 aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc gtgtcgataa aatcgatatc
    23161 agttttccag aaaaaatatt caatgctttt gatacgaaag aaacatcgat acctattggt
    23221 cactatacaa attatgcaat tgaaccaaca tgcggtttag ctacgatcca tgattttatc
    23281 gggaaagtgg atgaaccacg ctattttatg gatcctcgaa ggatggatgc ccgcattctc
    23341 tggtttacca gcggatttgt cgagtatcag gcacctaatt ttttaaatac agaggataca
    23401 ttggagatgt tggaagtttc tgtggaaatt tcttctgaat ttcctttttc aaatgacaat
    23461 tggccttcag atatcacttt cagcctaaat ggtgtggagc taggaacatg gacgagccct
    23521 ggagattttg ctgatatccg cggtaaatat acgcctgatt ggtatccaga taatcttaat
    23581 caatacggct tgctgaagac gatccgaatt accaaacact tgacgaatat gaatggagaa
    23641 cccttgtcaa acatcacgat caacgacatc cctaaagagc aagacacttg gcatttgcga
    23701 atcgaagtga aagacgatgc caaacatgtg gggggctgta ctttatttgg taaaggattc
    23761 ggtaattacg atcaggatat caaattaaaa gtttactaca gctgatattt ttcttttcta
    23821 ttttataaaa caaaaacagc caatccctat gaagggacgg ctgtttttgc tttattgtta
    23881 tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt ttatgttgtg tcttgttcca
    23941 ccatgcttcg attttttctt gtgcttgagc gggaacttct tttccttcta gataatcatc
    24001 aatttcatta tatgtgacac ctagtgcgac ttcatctgca atcattggtt tcccatcttc
    24061 aagatctgca gtcggaattt ttgtgtataa tttttccggt gcattcaatg cttgaagcaa
    24121 ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa atgtcggctc caccatcacc
    24181 aaatttcgtg aagaatccag taatgttttc tgcagcatga tctgtcccta atacggctcc
    24241 tgctctttct ccagctacgg catattgcgt aatcatacgt tgacgtgctt tgatatttcc
    24301 tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat acttgtactt gtgcatcaac
    24361 agctggtttg atatttactc gcagactaac atcgggctgg ataaagtcaa gagcagcttt
    24421 tgcatcttct tcatctgctt gttcaccata aggaagacga acagcgataa attgatagtt
    24481 ttcatctttt gtttcttcac gcatttcttc catcgttagt tgcgccaaac ggcctgctaa
    24541 agtagaatct tggccgccgc tgatacctag tacaaaagtt ttaagaaacg gatatttttt
    24601 caaatatgct ttcataaagt caatactttt acgtatttct tcttttggat caattgttgg
    24661 tttgacacct aattcattga taatttctgt ctgcaggctc atttattctc ctcctatgct
    24721 tctgtatgaa gttctgctac gctttttttc attcgttcca tgatagccat tttatggttc
    24781 cagcattcag tagacagatc gactgggtat ttttgcggat tcaagtctcg tttatactct
    24841 tcccatagtg aatctagatt ttcttttgta tattctttga tttcgtttag tgcaggtaat
    24901 tcgtaaactc tttttccttc gataaagata tcttgtaaaa ctgggcgagc tgtaaagtct
    24961 cgaacagttt tattgataaa cgtatgcact ggatggaaca tgaagatagc ttcttcttct
    25021 cgagggtctt catcccataa tgtcacgtag tctccttcag atttcccatc aaaatttcga
    25081 gtgatgcgcc acacttgttt tttccctgga gtagttactt tttctgcatt gcttgataac
    25141 ttgatcgtat ccatcatttt tccttcatca tcttcgatcg atactagctt gaatactgca
    25201 ccaagggctg gctgatcata ggctgtgatc aattttgtcc caacacccca tacatcaatt
    25261 ttagcttttt gcatctttaa attcaaaatc gttgcttcat ccaagtcatt cgaagcatag
    25321 atttttgctt ccgtaaatcc ggctgcatct aattgttccc gaacacgctt agatatatag
    25381 gccatatctc cactgtcgat gcgtacgcct tggaagttga ttttgtcacc taattctttc
    25441 gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat cataagtgtc gactaagaac
    25501 acgcagtctt tatgggtttt agcgtaggcc ataaatgctt cataatcatt tccataagat
    25561 tggactaacg aatgagcatg ggtcccgcta gctggtatcc caaatatctt cccagcacgt
    25621 acattgcttg ttgcatctgc tccgccgata tatgccgctc tagttcccca gactgctgca
    25681 tccagttctt gtgcccgtct agttccaaat tccaatagtg gatcttctcc gatgacagat
    25741 ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat tgaccatatt caacagtgct
    25801 gtttctacta attggcagtg cgctaaaggc ccttccactt ggattaatgg ttcatttgca
    25861 aaaactagtt ctccttcacg agcagaacga actgttgctt taaattcaaa attttgtaaa
    25921 tactccaaaa aaccttcagg atagacttct aatccacgca agtaagcaat atcggaatca
    25981 ttgaacgtca gattctctaa ataattgact aaccgttcca atcctgcaaa aaccgcgtat
    26041 ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa cagcatgtaa atcagctcga
    26101 cctaattccc agtatgtctg catcatattg atttgatata gatccgtatg cagcgtcaaa
    26161 ctgtcgtctg ggtaagtatt attcatcttg tattactcct cttggcaagt tttcatttcc
    26221 tacccattat aacaaaaaaa attaatagga aaagaaatct tccatttttt ctgaaaaagc
    26281 acatgtttta cggatatttc ttgctaaaaa tgaactccat ctgctaaaac tatcctttct
    26341 tattggtatt taacctaaac gagaaagaat acttatttta ttcaatgtat ccgagacacg
    26401 aagaaattag cgttttctat ttttcttact tgataaaata agtagatttt cctactacaa
    26461 tcgtagccgt taagataccg atgattgaac aaatataacc aaatgtctct acaacataat
    26521 caatggcaaa agtttttgaa gcaataatac gtctttcctt ttttgcttct tatccccaaa
    26581 gaaacggata taacttatta tgtattgaat ttttttggaa aggcgaatta tgacaagata
    26641 taccttgcgt tgaaaaaact cgcggaaaaa atatcacacg tttttaaaaa gatacaaagt
    26701 aagaaagcag ctgtcaatag aatggaaaca aaaatggcga gacatcaatc agtctcgcct
    26761 tgttttttat tgtatacatt agatatggag caggttacca taaagatgat tattagtcgt
    26821 tattaaatag aatccttcgt atttttttgt tctatcacta caatatcttt atttggacgt
    26881 ttgaattgta ttccggcacg ttctagctcc tgtttcactc ctacatggac tttgacatct
    26941 tctcgtgtca tttttaaaac gtgatgaatc gcatagtcga tttcttgcct tgtgattttt
    27001 ttcttcgtat tgatcatcac gacttgcttt ttatcatatg tgtctaccaa tagcagttgt
    27061 gttcgatcta acgaaaataa tttgtaataa ttaatagccg tattcccaaa aaagaattcc
    27121 actactttag gataaaatgt cttaatattt aaattactat tcacaggtgt ttcgattagc
    27181 ttcatctcat tcctcttttc tatatagtcg atttagatcc aatcttaagt tatgttacca
    27241 tctttcctag cattaaggaa tcggttacaa ttgaaccttt aaagacaaaa ggatttacct
    27301 tttatcactt aatagtataa cataatttcg tgagaaaaaa atacaatttt ttcttgacca
    27361 tctcgttacg taaaggatta tgcttacatt tgtcaggagg aaaaataatg gagtacacaa
    27421 taaagaaaat gtcagagata tcaggagtca gtccgagaac cttgcgcttt tatgatgaga
    27481 ttggactgct aaaaccagct aggatcaatt cttcaggtta tcggatttat ggcaaaaaag
    27541 aagtcgatcg tctgcaacac atcttatttt atcgaacaat ggcattcaag ttggatgata
    27601 tccaagaggt cttagacaat ccatcttttg accaccagaa agctttaatc aagcatcagc
    27661 aaatgttgct ggaaaaacgg gcacaaatcg ataccctctt gacaactgtc caacagacac
    27721 ttgatatgta cgaaggagga agaaaaatga gtgacaaaga aaaatttgaa gggtttaaac
    27781 aacaaaagtt gaaagaaaat gaagaatcct atggacaaga gattcgacaa aaatacggaa
    27841 aaaaaaaggt tacagcatcc aatgaaaaat ggatgaatat ggataaagaa acgtatgaag
    27901 aaatgcaaac tgttgaaaag cagatgttat ttgatctcac tctttactta aaagaaccag
    27961 aagatgaaag cttagcagac cgtatcttcc aagctcataa gaagtggttc tcttacagct
    28021 ggcctgaata tcagccaaaa gcgcataaag gactaggaat gatgtacgaa gccgatgaac
    28081 ggttcactgc atattatgac gagcgaagtg gtcatggtgc agcaaaagct ttaaatgaaa
    28141 ttatccaaaa aaaggcgtaa tcttttacat gatccaacaa aaaagtacac gtaaaatgac
    28201 ctaataacaa aacagcagac acccaagtta gatttttatg ctaacttttg gtgtctgctc
    28261 cattctttca caagtttttt catcctactt taaatatatt catcgttgaa taaacgtata
    28321 aggtattttc actttatcct ttttttctgt aagaaacaat tgaaatgcca tttctccgca
    28381 agcttccaga tggtggtcga tggttgggaa accaagaagc tcgctgatca gcaaattatc
    28441 gcgtccaatc accactggtg tcttatcttg cagatagctt tgcaagatgc ctgctgcaac
    28501 catatccgaa tttgtaaaga caccatcaac tccaagctct ttaaaagaga agcctgcttg
    28561 ttttcctttc tctgcatcta tacaatccca aaaaacaagt gattcatcaa aagatggaaa
    28621 aagttgatga catagctgca aagtgatttt tgagttataa cttagcctgc cacttcgccc
    28681 caacgtgatg cccaattgct ttataccttg ctgcttcaaa taagtaagac cttctgtaat
    28741 tgattgttct cgatcaataa agacacagct tgcctgtttt cccttgattt cttcacaaaa
    28801 aactagaggt ccatattttt gatatgccaa taaatcatct agtgtattgg cacgagacgt
    28861 aatgatcaat ccatcgaaag ctttagctgc aaattcttca agataccttc gctctttttc
    28921 tttatgatag cccgtcggta aaagtgtcac tttgtaatca taatcaaacg ctgcttcaat
    28981 gatcccactg atcaactgat caaaatacgg atgattggta taaggcagaa tcactccaat
    29041 gcttttcgtt tttccataac ttaactgtct ggcatttgca ttagggatat aatcgacttc
    29101 tttcatgacc gcaagtattt ctttcctttt ttcctcatct acatatggat gtccattgat
    29161 tacacgtgaa atagtagaaa ctgaataacc tgtgagcttt gcgatatctc gaatgtttgc
    29221 cactgctgct tcgccaccta tacaaaaaga ttttcttgta aatagtctac cacagctgga
    29281 ccgcattcaa aaaactgata catttttcct tcatgcgaaa aactgatccg ctgcccgccc
    29341 caatatatat cttttgtcaa attttcgatt tcattcattg gtatttcttt tactatattc
    29401 ctattcaacc cttgaaaact gtacaacgtt aatacggatc ccttgaactc gacaaacgca
    29461 taaaaataat tgttcgttgt gccatctgtt atctctacat aagtattcat tgcaagccct
    29521 ccttttgata ctttgagtat agtgtatgaa acgcgtctca tagcaaggag tttgttttgc
    29581 caaagaaaag ttttattcct ctttcattat taccaaagtc tcttatttta aattgaatac
    29641 attataatga tactgtaaat atatctttat tattagtgaa tg
//
LOCUS       DAIGTA010000034        29571 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.034, whole genome shotgun sequence.
ACCESSION   DAIGTA010000034 DAIGTA010000000
VERSION     DAIGTA010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.034"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(47..1342)
                     /gene="purB"
                     /locus_tag="NOB43_001607"
     CDS             complement(47..1342)
                     /gene="purB"
                     /locus_tag="NOB43_001607"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCI0982467.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1355..2479)
                     /gene="purK"
                     /locus_tag="NOB43_001608"
     CDS             complement(1355..2479)
                     /gene="purK"
                     /locus_tag="NOB43_001608"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCI0982468.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2472..2960)
                     /gene="purE"
                     /locus_tag="NOB43_001609"
     CDS             complement(2472..2960)
                     /gene="purE"
                     /locus_tag="NOB43_001609"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCI0982469.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3376..4683)
                     /locus_tag="NOB43_001610"
     CDS             complement(3376..4683)
                     /locus_tag="NOB43_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCI0982470.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4686..5267)
                     /locus_tag="NOB43_001611"
     CDS             complement(4686..5267)
                     /locus_tag="NOB43_001611"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCI0982471.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5383..5480)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5839..7131)
                     /locus_tag="NOB43_001612"
     CDS             complement(5839..7131)
                     /locus_tag="NOB43_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0982472.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7128..7751)
                     /locus_tag="NOB43_001613"
     CDS             complement(7128..7751)
                     /locus_tag="NOB43_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982473.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7754..8590)
                     /locus_tag="NOB43_001614"
     CDS             complement(7754..8590)
                     /locus_tag="NOB43_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0982474.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8607..9494)
                     /locus_tag="NOB43_001615"
     CDS             complement(8607..9494)
                     /locus_tag="NOB43_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0982475.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9510..10793)
                     /locus_tag="NOB43_001616"
     CDS             complement(9510..10793)
                     /locus_tag="NOB43_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0982476.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11476..12159)
                     /locus_tag="NOB43_001617"
     CDS             complement(11476..12159)
                     /locus_tag="NOB43_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCI0982477.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12177..12794)
                     /locus_tag="NOB43_001618"
     CDS             complement(12177..12794)
                     /locus_tag="NOB43_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0982478.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12804..13628)
                     /locus_tag="NOB43_001619"
     CDS             complement(12804..13628)
                     /locus_tag="NOB43_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCI0982479.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13621..14181)
                     /locus_tag="NOB43_001620"
     CDS             complement(13621..14181)
                     /locus_tag="NOB43_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982480.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14355..15311
                     /locus_tag="NOB43_001621"
     CDS             14355..15311
                     /locus_tag="NOB43_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0982481.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15616..16572)
                     /locus_tag="NOB43_001622"
     CDS             complement(15616..16572)
                     /locus_tag="NOB43_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HCI0982482.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16676..17278
                     /locus_tag="NOB43_001623"
     CDS             16676..17278
                     /locus_tag="NOB43_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0982483.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17366..18865)
                     /locus_tag="NOB43_001624"
     CDS             complement(17366..18865)
                     /locus_tag="NOB43_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCI0982484.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18881..19405)
                     /locus_tag="NOB43_001625"
     CDS             complement(18881..19405)
                     /locus_tag="NOB43_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCI0982485.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19703..20452
                     /locus_tag="NOB43_001626"
     CDS             19703..20452
                     /locus_tag="NOB43_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI0982486.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20443..21228
                     /locus_tag="NOB43_001627"
     CDS             20443..21228
                     /locus_tag="NOB43_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HCI0982487.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21197..21913
                     /locus_tag="NOB43_001628"
     CDS             21197..21913
                     /locus_tag="NOB43_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0982488.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22015..23049)
                     /locus_tag="NOB43_001629"
     CDS             complement(22015..23049)
                     /locus_tag="NOB43_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HCI0982489.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23053..24111)
                     /locus_tag="NOB43_001630"
     CDS             complement(23053..24111)
                     /locus_tag="NOB43_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCI0982490.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            complement(24332..25480)
                     /gene="nagA"
                     /locus_tag="NOB43_001631"
     CDS             complement(24332..25480)
                     /gene="nagA"
                     /locus_tag="NOB43_001631"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCI0982491.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(25556..26392)
                     /locus_tag="NOB43_001632"
     CDS             complement(25556..26392)
                     /locus_tag="NOB43_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0982492.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(26576..27793)
                     /locus_tag="NOB43_001633"
     CDS             complement(26576..27793)
                     /locus_tag="NOB43_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0982493.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(27942..28121)
                     /locus_tag="NOB43_001634"
     CDS             complement(27942..28121)
                     /locus_tag="NOB43_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982494.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            28176..28259
                     /locus_tag="NOB43_001635"
     tRNA            28176..28259
                     /locus_tag="NOB43_001635"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28210..28212,aa:Leu,seq:gag)
     gene            complement(28499..29497)
                     /locus_tag="NOB43_001636"
     CDS             complement(28499..29497)
                     /locus_tag="NOB43_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982495.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKC
                     QNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLS
                     LFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVW
                     ASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         8842 a         6305 c         5064 g         9360 t
ORIGIN      
        1 tatttttgct attctatttt aattgaattt tgcaactcac tcttctttat tccaaaccta
       61 ctcgtttgaa tatcacgtca acgtttttca aatgatgatg ataatcaaag gcatcgtcta
      121 tttcttcttt agataatacc gatgtgatgg ttggatcttc ttctaacagc gggcggaact
      181 gcacttggtt gtcccaagcg tacgcagttt ttggctgaac aagatcataa gcttcttctc
      241 ttgtcattcc cttatcgatc aatttcagca taacgcgctg gctataaatc aaaccaaatg
      301 ttgcagacat attccgcttc atgttttcag gaaagaccgt tagattttta acgatattgc
      361 caaaacgatt taacatgtaa ttcaataaaa tcgtggtatc aggcaagatg attcgttctg
      421 ctgaagaatg agaaatatct ctttcatgcc ataatgtgac attttcatag gcagtgacca
      481 tgtgtccgcg caccactctg gctagaccag ccatattttc tgaaccgatc ggattccttt
      541 tgtgcggcat agcagaagaa cctttttgac ctttcgcaaa aaattcttct acttcacgtg
      601 tttcggattt ttgcaatccg cgtatctctg ttgcaaaacg ttcaatactt gtagcaataa
      661 gcgccatcgc tgagaaatat tcagcatgta gatcccgagg gagaacttga gtagagattt
      721 cttgtggacg gatccccaat tgtttacata catactcttc aataaatggc gggatatttg
      781 cgaacgttcc cactgctcct gagatttttc ctgcttctac tccttttgcc gcatgttcaa
      841 atcgttcgat gttccgtttc atttctgaat accatgtggc aagtttcaat ccaaaagtag
      901 ttggttcagc atggacaccg tgtgtccgac ccatcatcac tgtatatttg tgttcttttg
      961 ctttttcgcc aatgatttcc gtaaaacgtt tcaagtcttc ccgtaaaata tcatttgctt
     1021 gcttgatgag atagccataa gcagtatcta cgacatccgt acttgttaga ccataatgga
     1081 cccattttct ttcttctccc aatgtttcag aaaccgctcg tgtaaacgca acgacatcat
     1141 ggcgtgttaa tttttcgatt tccaagatcc gatcgatatc aaatgatgca tgctcacgaa
     1201 tttttttcac atcttcttgc gggatttcac caagttctgc ccaagcttca tctgctaaaa
     1261 tctcgacttc gagccacgca cggtatttgt tctcttccgt ccagatattc cccatttcag
     1321 ggcgtgtata acgttctaac atgttttttc tcctctaatc ccaaatattc gtttgtttga
     1381 tttcttccag cgtttgctgg atgtcttctg tcaagatagt gatatgtccc atcttgcgac
     1441 ctttttttgc ttgttttttt ccatagaaat ggaattgcca gtctggctta ttctcaatca
     1501 agcgatagct ttccagcagt tgttctccca aaacattgac cattactgca ttgcttatca
     1561 aacgtacttt ttctcctaat ggccaaccac aaatacctcg aatatgggca tcgaactgac
     1621 tcatagaaca agcttcaata gaataatgtc cagaattgtg aggacgagga gctaattcat
     1681 tcacatatag cccgcctgtt tttgttaaaa acatttctac ccctaaaaca cctgaaaggc
     1741 tcactgcttc tgcaatcaca cgggcaatac gctcagcctc ctcgatcaca tcctgatcaa
     1801 tcgcggctgg agcaatcgtt tcatgaagaa tattgttgtg gtggatgttt tccacgaccg
     1861 gaaaagtcgt gaaatctcct tgaccatttc ctgccaccat gatcgaaatc tctttttcaa
     1921 acgggatcca tgcttctaaa acacaggttc cttctcttaa aaggtccatg gcaggagcta
     1981 gatccgcccg acttttcaaa acatactgcc ccttgccatc atagccgcct cgagtggttt
     2041 tcaaaacaca aggatagccg atcccgtcaa tcgcatcttg gatatccgtc ggactgacga
     2101 tcgttgcata aggagcaatc acgatgttat tcgtttccaa aaaagatttt tctaacaggc
     2161 ggtcttgcgt aatcgcaagc aagtctgtcc cttgaggaat aaatgacatg ggtaaaatcg
     2221 catttaacgc ctctacactg acgttttcga attcataggt aatgacatct gttcttctgg
     2281 caagctcttt cagcgcaaag gtgtcatcat agacactttc aatgtgccaa tctgcaactt
     2341 gtgcggctgg acaatcgctc acaggatcca gcacacctac tttaaagccc atttcttttg
     2401 cactaatcgc catcatacga cctaattgac cgccaccgac gatcccgatc gttgaaccag
     2461 gcaacaaagg tttaaccaag ttgatcacta ctttctataa cagttttagc caacattgaa
     2521 cgtctttcag ccaatttagc ctccaattct aaatcataca tggaaagcat ctgtatcgca
     2581 agtagtccag cattaattgc tcccgctttt ccgattgctg tagtagctac aggtactcct
     2641 ccaggcattt ggacaatcga aagaagcgaa tccaaaccat ttaatgttcg tgattggacc
     2701 ggtacaccga taaccggcaa agttgttttt gatgcgacca tacccggcag atgcgcggct
     2761 ccccctgctc ctgcaataat gattttgatt cctttttttc gagcgttttg tgcatattca
     2821 aacatcaaat ctggggttcg atgagcagaa acgacctttt tttcataaga cacaccgaat
     2881 tcatccaata tttgacatgc ttctttcatt gtttcccaat ctgaagtact ccccataatc
     2941 acagagattt ttgctgtcat tgtttttcct cccagttttt ctacattcat attttaacaa
     3001 tcactttttt tgatgtcaaa gaaatttcga atgttaacaa agaaaaacat tttattgttc
     3061 gtgtttatta aagataaaaa aaaggaatgt gacaaaagtt aggtcacatt cctttttatg
     3121 gataaacggt gttctcctgc caactcctcg gtcacaagga acaatattca acaaacatga
     3181 gaagcttttt tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc
     3241 ttccttcaac ggtgttcaat cagctgaccc tcggtattag ctcaaacaaa cggcaaaata
     3301 cgaggaacta tttttccgtt tgtttctcta acaatcaggt caaaacgctg atttcacaac
     3361 ctttcttttg ctctattact tcttgaaggc ttcttccaat atttcttcat cttttttcaa
     3421 tccattaaag atcaaattca atatgatagc cgtaatgcta ctcattacga tgccatttcc
     3481 agtgaacatt tgcaatgttt gcggcatttg actgaataat gtcggcgtaa cattgaaacc
     3541 cagcccaaat ccaacagaaa cagcaacaat caatagattt ttatcattgc tgaaatcaac
     3601 ttccaacagc atacggattc cttggactgc caccatcccg aacatgacta acattcctcc
     3661 accaagtacc ggctcaggga tgatttgtgc taacgcaccg attttaggga ataatcctaa
     3721 aacaatcaag aagaatgcag agaaatagat gggttttctt gttttgattc ccgaaagttg
     3781 aaccaatccg acattttgag aaaagccagt ataagggaat gtattgaaaa taccgcctaa
     3841 gataacggca agtccttctg cacgatatcc ctttttcaat tcttcttctc caacattttt
     3901 cccagtaatg tcaccaagtg caaaatatac acctgttgat tctaccatgc tgaccatgga
     3961 aatgatgatc attagtaaaa tcgaccatac gtcgaaagtt ggtttaccaa aataaaaggg
     4021 ttgtggaaca tggaacaacg gcgcatctcc aatcgcgctc agatcaatca ttcccatgaa
     4081 agcagctaag atgcttcctc cgactaaacc aatcaatacc gcgattgaac gaatgaaccc
     4141 ttttgccagc atttgcacgc ctacaattag gagaatcgtc acaaatgcaa gtagcagatt
     4201 tgttttgtca ccaaaatcag ctgctgttgc attacctcca cccattttct cgattgctac
     4261 aggaatcaaa gtcaaaccaa taacggtgat aaccgttcct gttactatag gagggaatag
     4321 ttttttaatt ttagaaaaga caccagaaac taacacaaca aagatcccag aagcgataat
     4381 agatccgtag atagctccta ctccttcatt ggttccgatc aagatcagtg gagctactgc
     4441 ttggatcgca catcctaaaa cgacaggcaa gccaattccg aaaaatcggt taactgtcaa
     4501 ttgcaataat gtcgctaatc cacacataaa gatatcaatt gaaatcaaat aagtcatctg
     4561 ttcttgatta aagcctagtc ctgtaccgat caaaagaggc accgctactg ctcctgcata
     4621 catcgctagc agatgctgca gccctaaaac cgcagctttt ccattttgtg tttctttttc
     4681 cacgattatg cgtcctcctc aagaaactca acttgtccat tcgtcaagga agcaatacgc
     4741 gcaagagaaa cgactctcaa tcccatttct tcaagtaact gacgtccatc ttggaaagac
     4801 ttttcgatga cgatcccgat tccttctact tgcgctccag cttgctggca taattcgatc
     4861 aatccttttg ccgcttgtcc gtttgccaag aaatcgtcga taatcaatac tttgtcttct
     4921 gaagataaaa atttacgaga aatagaaatc gtacttgtca cttgtttcgt aaaagaataa
     4981 acagaagctg tcaataattc ttcatccatc gtcaaacttt ttgcttttct agcgaagatc
     5041 attggaacat ctaattctct tgcagcaaat aaagctggtg cgatcccaga agcttcaatg
     5101 gtcacaactt tcgtgattcc ttgttcttta aatacttctg caaaccgttt tcccatttgt
     5161 tccatcaata cagggtctac ttggtgagtg acgaagctgt cgacttttaa tacgccctcg
     5221 cctaatatac gtccgtcttt ttgaatacgt tcaactaatt ctttcacttt atttgctcct
     5281 ttatcattta ttaataccga aataaccgct tttgtgcaaa aacctactat gtttctgtta
     5341 aagaaaaaca ccctccactt tatcataaga aaagaagggt gaaatagcca atcttttact
     5401 tatagtccag catttacggt actggctaga aactgtcatc catattatga cgatatataa
     5461 gtaggtatgt aaaactaata atagtgtaaa ttcattttct tgcaactgtt ttgcacgtga
     5521 aggcagtttg ccatatttga ataaaaaatg ttgtttcaaa tattgaaaac agtctaacac
     5581 tactttctga aactgacaac gtggtttact tatttttttg taaaatctaa tgatttttaa
     5641 tgcattattc ctttttgttc gggtttaaat agttattttt attttctcct atctaaaaaa
     5701 gcagcccaca taaaaagaag gcatgacaaa aagcatgtca tagccccttt ttccgaataa
     5761 atagtgttca aaagacagcc tatcggcaat aaggcaagat tttataaact acgggaagta
     5821 atttccgtaa atctattctt attcttttaa gctgacaagc tcgtcaatca ctactgcttt
     5881 tcctgaagca atagaatgat ttgctgcgat tcctgtcaaa atcgacaaaa taccatctac
     5941 gtgagttgct gcccgattcc acggatcttc ttctttttct tcaccaaata gatcatctaa
     6001 taaacgcgga tctcctccgc catgtccgcc cgcttcttgt tcgacgatta cctcatatgg
     6061 ctcaccgaac atcggataga catggatgga ctgaagaacg gctgctcctt catccttttt
     6121 atctccacct gcattgatgt aagacttttc gatcactttc atttcgatcc gtcctttgct
     6181 gccattgaaa gaaacattga atccttccca cggcatatac gcgtttagcg aatacgtcaa
     6241 aatcgcacca gtttcatatt tgaccgttac gcctagtgta tcttcaatag agatatcatc
     6301 ggaaaataca ctgcggtcac gaatatatcc actgtctttt tctgcttcta aatacatttc
     6361 tcgcaattcc tcattggctg acaggtctat agcaaatgga tcagctttag ctagttcgct
     6421 tccatagcat cgactgtaaa atatttctac tccgcgtttc tccgcattat gcatcccata
     6481 aaagtttaat ccaccgaatg caaatacctt ttggggacgg ctgttcaacc aaaaattcac
     6541 tagatcaaaa tgatgggtag atttatgaac aagaagcccg ccgctattgt gcttatttcg
     6601 atgccatctt ctgaaataat ctgccccgtg ttgcgtattt aacagccatt cgaagtggat
     6661 agaaaacaca tcaccaatca catcactttc tatcagttcc tttatcttcg tgtgatacgg
     6721 tgcataacga taattaaaag tgactcgcag gcttcttccc gtctgttttt ggaccgttat
     6781 tatttcttga gctttttcct catcgatagt cagaggtttt tcgcaaataa catcatatcc
     6841 ttttttcatt gcacgaatga tataatcatg atgcgttcga tctactgacg taataatgac
     6901 ttcagccggc cgtacgtcat ccagtagttg ctcaaattgt gatggcatac atgtctttac
     6961 ttttttctgt ccatacttgt tcacaagtat ccgatttgca taatccatcc ttgtttgaga
     7021 tacatcacaa aaaccgacta gttcacaagt ttgatgatac gtagaggcaa ttgcctcata
     7081 aaaaaaacgc gctctcccac caagtccgac ttgtacatat tttttcttca tttaaagtca
     7141 ttctcctttt cttttaagca aaatactgtg acaaatggca gccctggata cagtaatgca
     7201 gtgagtaaaa aatcatgctg tatacaccag aacagtccat acaaaaggca taaataccac
     7261 agaaacccct tgacgttttt tgacaacagc cagatattcc ttttgatcaa ataaacaaga
     7321 ctatctgctt tatcttcttt gcagatatca attagcgtac taaaaaaact atgggataca
     7381 aaaagcaaca gacacaatag aaaaggaatc agataccaag ctccaatctt tcccactaat
     7441 aaataccaat caactgcaaa aataatgaca aacagctgaa acaacgtaat gatgaaacac
     7501 atccgtttga tttttccttt cctccaacat accttttttt ctgccaagta atggacagat
     7561 agataataag aaggatacat catcaaaaaa taaatcagat agacaacacg agcagacagc
     7621 actaatccta aagtgaacaa acatcctaga actaaagcga aaagagcatt actgataaga
     7681 ctggttaaaa aaatccgaca gacatagtag ttgagcttgt aaagaaacat ctcttctatt
     7741 ggctttttca tattcagccc ttcagaccgc ttgtactgat cccctggaca agatatttat
     7801 tgaagaataa gaaaatcaga aaaaccggta gcagcgacaa cgtagacatc gcaaacatac
     7861 tcgcgtaagt cgtactagat ccagcgtctg caaataattt gatggcaatc gataccgtgt
     7921 aagatctcgg cttgtttaaa taaatcaatg gtcccatgaa gtcgtcccat ttccaataaa
     7981 actggatgat gatcgtcgtg atgatcgaag gtttcagcaa aggaaaaata attttggtaa
     8041 agacactata cttgctgcat ccgtcaataa tcgctgattc atctaactct ttggggatgc
     8101 tgaccatgaa ttgcatgatc tggtaaatga aaaatgcttg tccaaaaaaa tgtggtaaaa
     8161 tcagcggcac atacgtccca accaaattca gccgattgta aataataaac tgcggaatca
     8221 aaatcacttg tgcaggaatc atcatcgtta ctaacatgac gacgaaccag aatctttttc
     8281 ctttgaaatc gattctcgat aatgcgtaag caatacaagt cgagctcaga actgtcccta
     8341 tcgtcgaaac tgcagagatg acaaacgaat tcctaaagaa agtaaaaaat gaaattccag
     8401 caaaccccgc ccatcctttt gcgtaatttt cccattgaaa agtctctgga atcaaattca
     8461 gcgaaccact cataatctct tgatccgttt taaaagaacc tgcgatcatc cataagaccg
     8521 gataaatcat gactagacct aatagcaaaa taaaaccgta ttgaaaccat ttcgttactg
     8581 tattattcat ttcttcctcc tctcattcac acaacgaccc atttttttga tgatttgaaa
     8641 atcagaaagg tgacagctcc cataatcaac agcatgatcc acgaaatagc actagcatac
     8701 cccatagaat taaaagaaaa agcttggtta tacacataaa gagcataaaa gttcgtggca
     8761 tcattcggac caccttgggt aatgataaat gcctgcgtaa aagtcataaa cgccgcgatt
     8821 gtctgcataa ccaagttata caaaatgatc ggcgaaagaa gaggtaacgt gatcttgtaa
     8881 aacgtctgcc atttgttcgc tccatcgatc tctgccgctt cataatacga gcctgggatc
     8941 tctttgatac ctgcagcaaa gatgatcatt gccgaaccga attgccaagc agacatcaaa
     9001 acaagaggga tcatgaccag tttttgatcg ctaaaccagg aaagcgcagg tgcgcctaat
     9061 cgttccagga aaatattcac taacccgttt ttagaaaaca actcccgcca aactagagcg
     9121 atagaaatac tgccaccgat caaactaggc acataataca aagaacgaaa gaaagtcgtt
     9181 cctttgatat tcctcgttaa aagataagca atcaatagac caaagatcag tttcacaggt
     9241 acagatgcaa atacatagag aaaagtgact cggatggagt tcaaaaaacg ggcatcactc
     9301 agcatcttta tataattatc caagccgatc catgagactg gatttcccaa acgataatcg
     9361 gtgaacgaat aataaagtga caagatcatc ggtatcactg ttatcaatag aaatcctagg
     9421 atgaatggag aagcaaatac gtaaccgacc acattgtctt gatccaagaa ccgttttagt
     9481 ttttcttttt tcatgccttc ctcctgctgc tatcctagaa tgtttgacgc aaactcataa
     9541 agactctctg ctgcttcttc tgctgttact tcttcataaa tgactttttc aactaaaaga
     9601 ttgtattggt cttgaatttc cggattcaaa gcactatcaa agacattcac ttcgccgttg
     9661 tccatatcgg aaatcatttc taaataatca aatgtcgctt gcaaagttgc atcatctgca
     9721 cgagcgagct gttctcgaat attcgacatg attggtacac cacgttctcc ttttaaaatt
     9781 tcattggctt cttcactgtt ttgaaagaaa tcaataaact tagcagcttc ttctttatgg
     9841 gctgagcttt ttgccatact cagcatttgc gaagaacgta aagggatacc agattctcca
     9901 tctgcttttc tgcgaggtgg attaatcaac tgaatctcca tatcttcagg agcccctgac
     9961 aatatttctg tcaactggtt acttgataga aacaccattg ccgcttctct atccctaacc
    10021 gcctgaaaag acagatccgt cgtacttgca gctccaccac ctggttctgg atgggcccct
    10081 ttgtctacca gatttttacg cagctggaaa aaatctgtta gatagtctgg attttcaaat
    10141 cccaagctgt tagatagatc ttcccgatta taaaaattca atcctttctc aacttgtggt
    10201 atttgaataa tacagccagc tataaaatct tcgaatcttg aaatagcata gattcctaat
    10261 tcttcagtga tttgatagct gatttgttca aattcatccc atgtccaatt tgaagctggt
    10321 tcagggatat ttaattgttc aaatatattt ttattgtaag caatcgcaaa cgaattcacc
    10381 ccgttagaca gtccaactaa ttgcccgtcg taagtcgtcg ttgctaaata ggattcatct
    10441 gcattagaaa tatcaattat cccttgctcc acatattcat ctaatggttc aatctgattg
    10501 atgtattgag gaaattgatt gttcagttgg aaaatgtccc agatatcatc tgatgctgct
    10561 agtgtaccta attttgtgta atatccttca taatcataaa attcataatc gatcgtcaca
    10621 tggggatttt tttcttcata aagctcgatt acttttactg ttgcatcgtg tcggacttgc
    10681 gaaccccacc aagccatgtt cagcgtgatt tttttgtcat cttcttgccc acaagccgtc
    10741 aagaagaata acataacact taaagctaag atgattctca ttcttttctt cattctctgc
    10801 acctctactt ccattgttat ttttcaatat actgtatttt tatacagaac atatttatta
    10861 aacgatcttt ttcaagggga ataaaaacca agacttgcct tatcgttctg cctaggatga
    10921 acaactcaat actttcaaga aaaattagat agtgctgatt cttctttcat cgctaaaaac
    10981 acttcttgct tcaatgatgg gaggataatt acgcaaagaa aaaaggatat cagacaactg
    11041 cccaatatcc ttgacatagc taaataagca tgcttcttcg tgtgcgctct tccctaaaaa
    11101 acagaaaaat aactagtaat tctgtatgaa attaggtaca atatacacgt cgatgcacaa
    11161 gcattgacta tggcaacttg attggtcagt tcccgctgac ttttcaagcc ccgacaattt
    11221 agctgctact aaattgtcgg gtgccttttt tagtttttat tcgtttttca ttctatagaa
    11281 agcgcttcaa taaatcaaga catttttttg ttagaatgct aataataaca aaaggtttta
    11341 actcttctta tgtacattac aggtaaaaaa acaaaaaaat ttctcttttt tttgaattct
    11401 gaacaaatag tactggagta caaaagacga ggaagagcca ctatctgctc ttcctcgtct
    11461 tttgattctc acctgttatt catgattctt tttctcagtt tcccgatatt tttccatttt
    11521 acgactaaaa agctctccgc tacttggtgg cgtatatgtg atggcatttg ctcctgcttg
    11581 aatggtctca gcaatacttt cttccgttgg accacctgtc gcaatgatag gaagttcagg
    11641 atatttttta cgaaaatggc gtactgcttc tgcagtttct ttacctgcac tgatattgat
    11701 aatcgaaata ccagctgcta acttttcatc tatttctgta tatttcgacg ttaccgtact
    11761 gataactgga atatcaacta ctcgacaaac ttcttttact gtctctaaag gcgtaggacc
    11821 gttcaaaacg acccctaacg aaccttgcgc ttctgcgaac atgctcatgt aggaagaacg
    11881 agcaccttgt gtcaaaccac cacctacacc ggagaaaact ggaatgtcag ctgcctcaat
    11941 aatgctttta gtaatcgctg gatgaggtgt aaaaggatac acagcaatta ctgcattcgc
    12001 atttgtatta cgtatgatcg caatatccgt agtaaagatg atcgaacgga tcaattttcc
    12061 aaatatcttg atcccgcttg cttctaaaat gatttccggt actcttacga tatcttttct
    12121 caattccgtc atgatttctg gcgtaaattg ttctgccatc agccacttct cctttgctat
    12181 ctccggtcat actgattcaa ttgatacgtc tcgatgacct ggatgatttt ttgcgcataa
    12241 ccggggtctg tcgcataacc tgcatcttgc aatgcttgtg cggcttcctg atagttggtg
    12301 gccgtaatca ctttttcata cagcgcagga ttccaatcta ctccttggac gaacagttgt
    12361 gtatggtcat ccatggactg ttcccatgaa tcatacactt tgaagtctcc ttggatagtt
    12421 atccattctt cgttaacaaa ttcctttgtt tccaggctta ctttcttctg atccccataa
    12481 gccttgatcc cgaaaagatt attgtatttg ctagccaagg tactttttcc ccaatttgat
    12541 tctaatatag cttgtcctaa aatgatacta ggaagcactc cataaccatc ttgtagttct
    12601 tgggcatgcg gaacaagccg ttcaataaat tgctgatggg attgcgcttc attttcttgc
    12661 tgattatcag taaaaggaga agacagattc ttcaaggaaa aaacaaaggc taagagtatc
    12721 actgctacac cggcaaccac tgctggccaa cggatattct tgcgcttttg ctttttccac
    12781 ttttttttcg ccatgatcaa ttcctacttt tcatttaatt cattcagata ttcttctagc
    12841 gtcaattggt gtttggtgat atactcagcg ttttctttac cgacataacg taagtgccaa
    12901 ggttcatatg tgatcttagt tatatcttcg tgtccttttg gataacgaac gataaatcca
    12961 tactgcgcag cattatctgc gatccattta gctccaggct gatctccgta acttgcatcc
    13021 aatacagtag aaggataact gttgtaccag ttttgatcga cgacatcgac tgccagacct
    13081 gtgtggtgtt cgctgtatcc tggctccgta atcgtttctt tagtaatctt tgtcgcctcc
    13141 tcttctgata caccttgacg actcatcaca tcttggacat tttgttcgaa aacttgttgt
    13201 tgggatgata cagaccggta agctgagacc atcactaatg gaaatccagc tgcttcagca
    13261 gccttggcaa atgcttcata ttctggagca atgcgtttgt cgatcaagta tccgttactt
    13321 aatgatgcca attgagtaga ctcatcaatt tctttttcta atttgtgatc tggaccaacc
    13381 aaaactagct tccaatcgtc tgttttaaca tctggcaatt gtttggacgt acgatctttt
    13441 gtttctttgt cctttacctt gctgctggtt gtttgactgt tcttttcttt actagcagtt
    13501 gttttggtgc ttgttcgttc gactgcttga ttgccggctt gaacatgcga atcatcatcg
    13561 ctaaaaataa catagcccat tgctgcgatc ataatcacaa ctgctccaaa tcctaaaaat
    13621 ttattcactt gaaaaatcct ttcgttgttc ttcacgttcc ccattcgcct catgaacgta
    13681 agtttcttcc agattttcat tcacccaatc gagaagttcg attttttctc cttcgatctg
    13741 tttttgaaca tctgctggca gacgaaaatt caaaatatca tcatagcccc attcatcata
    13801 ttgaatactt actttcaagt caaggtatct accagcctgc tgattatttt tcaaagggat
    13861 cagctcgact tttgctgctt tgctgctaag ccatttttgc gcgatgcgtg ttttgatttg
    13921 cttgtactct gcaacggcaa cgtttcgttt ttcgggaaaa ataatcgttt gacgcaaaat
    13981 cttttgcgtt agcatccatt cataatcagt gaaaagattt tttactttct gcatcgcttc
    14041 agatggcaga tttttctcgc catctttcca tttttgccat tgttctggac tgatcagcaa
    14101 gtattcatct aaaaaatttt tttcagtttc aaactgttct aataatacac tcataataag
    14161 atcaatatat acttgatgca cgtttatccc ctccttttaa ctattctact taagttttga
    14221 tcaaaaagca cctcttaaat cgctgctttc atttttttta atgtttcaag tcctctcctc
    14281 tttattcttc gtgatttttg ttataataat agacagacaa gaaactcaat ccaactatga
    14341 aggagcgttt tcagatgaaa aaatatcaat ggggaatcgt tggtcttggt accatcgcac
    14401 atgagtttgc cgaaagcttc aatcaagaga cgagcgaact aacagcagtt gcttccagaa
    14461 cttcagaaaa agcggaaaac ttcgctcacc gttacaatat tccaaaagct tacggaagct
    14521 atcaagaaat gttagacgat gctgaaatcg acatcgtgta cattgctgta ccaaatagac
    14581 agcatatcga ccatatcttg gcagcattgg aagcaggcaa acacgttcta tgtgaaaaag
    14641 ccatcacgat gaataaaaaa gaactggctg acgctatgcg cttagcagaa gaaaagaatt
    14701 tgatcttagc agaagcgatg acaatcttca acatgccact ttatcagcag ttacgctcaa
    14761 taatggatac aggaaaactg ggggctttaa aaatgatcca agcacctttc ggcagttaca
    14821 aagaaccaga ccctaaaaac cggttcttca atccagaatt agctggagga gctctgttgg
    14881 atatcggtac gtatgctgta tctttcgctc gtttcttttt gagctctcaa cctgaagtag
    14941 ttgcctctac aatggttcct tttgaaacag gcgtggacga acaatccgtc actatcttgc
    15001 gtaacaaaga aaatgaactt gctgctgtca gcttgacttt tcaggcaaaa atgccaaaag
    15061 tcggtatcgt tgcctttgag aacggttatg tgacgattgc tgattacccg cgtgctgatc
    15121 gtgcggagat cttatttaca gatggtacaa aggaattcat cgaaagcggg aatacatctg
    15181 aagcaatgaa ttacgaaata aagaatatgg tacacatgat tgaaggtgac ttgcccaatc
    15241 gctctctctt cttgacaaaa gatgtcatcg aaatcttgga tcaaatgcaa gttctatgga
    15301 aaaatatgta attttaaaag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
    15361 caaacaaaaa tagctcctcc tatttttcgt ttggctggac ttattaccgc agaggaaagc
    15421 ttttgaacac cgtttaagaa agaggttgtg agcctaccgt tcagctccga gtcacaagga
    15481 gcaatttcaa aaaacagctt ctcatgtttg ttgaatattg tgacttgtga ccgaggagtt
    15541 gacaggagaa caccgtttaa agaagaggtt gtgaaatcag ctttttgacc tgaatattag
    15601 ctgaattcac aacctctatt tttggatttt ttgttgggag aattctgcct tgatttcaat
    15661 aaaactttta aaagactgca aaaactggaa caattctgct cgatcctcga attcagggcg
    15721 actagtcggc agaggcattt gccgatacaa tacataaact tcttcaatac gtgttaaaat
    15781 ttgtctgcca tcatttgact ctgaaaatgt ttctgcagta taaatcaata aaccatagat
    15841 atgttttcca taataagctg gttgctggat tctctctaga ttttccagca tgtctttaat
    15901 cacattggcc tgtgctcttc tcatagagaa gtaagtttcg tagtatagcg gctgtctgag
    15961 ccagtagttt tcttgatgtt ctctggcatc ttcttggctt tcgcgaatga atgtcagtaa
    16021 atgttcgcat ttgatctgca catcttcttt attttctgat aaaagaaatt ctgccatttg
    16081 tctcaaaata tttcgaaatt ctttttcgat ctgtatttgg ttttccttca gctgcttcgt
    16141 acgatctggc atgtaaacat ttgcaagcaa agcaaatact aatccaatcg ccattaatcc
    16201 cgcttcattg ccgatcagct gccaagacat gttttcctcc actaaataat gagtgaccaa
    16261 aaccgaattt actactatcc cttcggttaa tttgaagcga gaggcaagcg ggatgaacag
    16321 gaataaaaaa agactgaagc caaaaatagt atacccaaca gcaaaaaaac tgaacagtgc
    16381 tgttgccgta gctaatataa aggctgcgat tcgattcatg cccgtacgca atgtagagcg
    16441 cttggtattt cctacactta ataatgcaat gatccctgca gctggccaat acaacagcga
    16501 taagctaccc gctgtgacca tcgaaaagaa gacactgatc actgttttga ctgttcgcat
    16561 tcctatacgc atttacttcc ccctttttta ttttaattat acttgaataa tgaaaaacta
    16621 gctatcagac aaaagtttag gtatgatagt aaaaagacca aaaaggagaa tctctatgca
    16681 atttggccgt tttcgactag gtatgcgtac gatcaaaagt gccttagctg tttttttatg
    16741 tatcttgttt tttcatttga ctcaacgagg aatcccgatg attgctgcat tatctgctgt
    16801 tttttctttg cgtcaggact tgactacaac cgtttctttt ggaaagtcta ggatcatcgg
    16861 caatacatta ggtggtacat tagctatcat ttattttttt gtcaaaagct attttcacaa
    16921 tgattttttg gtagaattga tcttgcttcc tattctagtt attattgtga tcgtcgtgtc
    16981 agatggtatt aacaataatt ccggtatcat ttccgcaata gctacgttgt tgctgattgc
    17041 gttgagcatc cctcaaggcg aatccgcttt gtatgctatc caacgtgtac tagatacttt
    17101 tatagggaca ttcattgcaa tcggtatcaa tttctttctt cgtcctcctg aaacagaaaa
    17161 gaaggaagaa ctatcagaag atttggtcga actccaaaag aaagaacgat tgctaagaac
    17221 aaatttacaa gagatagaag ctaagatcca aaaacaaaag aaaaatagcg aggactaatt
    17281 ttcttttgca ataaaataaa aaaatggaga gaagaacttt aaaaagtctt cctccatttt
    17341 tgattgaacg gtgaagtgta ctactttatt cttccttcat cgagttttgt tctgcctctt
    17401 ttggcgcttc atacatattt acttggctag tagtcccacg tgtcgacaaa ttctctacga
    17461 tttccttcaa gtcaagtcct gttgtcgctt ttagtgtttc ttgagtagaa gaaagcaaat
    17521 ttgtggcata atttgtcact cggttcgctc cactggtttc tcctgaactg cttcctgtat
    17581 cgacaacaga gattttttcg atatttccta gcggctgtgc tgcttcgcgc atcaattgcg
    17641 gtagcatatc gataaccata ctcaagacag ctgcttcgcc atattccttg aaggcattgg
    17701 cgatcttttg ttttgcttcg gcttctgctt ttccttttgc tagtgctgct tcggcttctg
    17761 cttgtccagc taaacgtgtc ttattggctt ccgcttctgc cagtgcttcc acacggaatc
    17821 gttctgcttc ggcttcagtc acttctttga ctttttgagc ttgtgcttct tgttctttag
    17881 cgtaccgatc ggcatctgct tttttcttca cttccgaatc atattgcttt tcacgacgtg
    17941 tgatttcttt ttcttccagt tcgatttgtt tttggcgttc tacgatttta atctgcattt
    18001 cctgttcgat tacttgttgt tgtgctcggg cactttctaa attgtaggct tggtctgctt
    18061 ttgctttagc aacatcttgt tcttgtttgt aggttgctaa tttcagttct ttttctttta
    18121 atgattctgc gatctctgtt tgtcgctgta attcagctgc ttgtgattct ttttctgctt
    18181 gagctttttt gatacgcgtt tcttttagag cttccgcttc tgctatatct gcatctcttt
    18241 tgacttgggc gattcttggt ttccctaaag agtcaagata accgtttttg tctctgacct
    18301 ctttgatagt gaaagaaacg atgatcaacc ccatttttgc aaggtctaca gaagcgactt
    18361 cttgtacgct ttgactgaac ttatcgcgat tttgatagat ttcttctaca gtcatagaac
    18421 caagaatcga gcgcaagtgt ccttctaata cttctcttgc ttcattttcc agttcttctc
    18481 ttgtcttgcc taaaaactgt tctgctgctg tagcaatctc ttctacagat gaaccgattt
    18541 tgatgatcga agtaccatca cacatcaccg gtacgccttg ttccgtatac acttcagggg
    18601 tggagacgtc caatttactc gataatagac tgatccgatt cgaacgttga aaaactggca
    18661 agacgaatgc gccacctcca cgcacaattt tgattttgtt attgctttca tcaatgtgca
    18721 catttttgct tcctaaataa cttccactga tgatcaacgc ttcatccggt tttgctgtct
    18781 ggtacttcgc tacaaagacg atcagcaaca tcagtaaaat caaagctgcg attgcgatcg
    18841 cgataaaaac aactggtatt tccatttaac acacgctcct ttaagctttt atcatgcttt
    18901 cataaggcat gacataacag attctttcct tgatctcaat gatcaatact ttcgttcccc
    18961 gctcagctgt ctgttcttgg gggctgtaaa aacaagctgg acgactaatg gaaccggtaa
    19021 cacttttcaa ctgaatttct cccatacctc gtacagggat cggtgtgatc acaacagcta
    19081 cttgtccttc cagagttttt tcagaagacg acatcgttga ttcggcatgt ttcatcggca
    19141 tcaatatata gaaattaagc aaaaatacca acactatcga tatgcctcca ctagcaataa
    19201 ataaaaataa agatgattga tctgttaaac gctcacctag aaaaccaaat aagcttgtga
    19261 aagttaacca agggataata agcatcggat caagcgggcc atcaaaatcg aatacatctc
    19321 caaaaataat caataggact gccaatcctg cacaaatcag caatgtatac caataaatcg
    19381 tctcaagtgc gattccccct atcatataca cgcctccttc catttctacg tctatcatac
    19441 caatgtttga aaattctgta tagcttcttt taccgactca gtggtgtttt ttataggaag
    19501 gttgtgttta tcgttgacaa tttgttaaat ttttgttttc atgttaaaat tttcacaata
    19561 aattccttcg aggtagccta tgtttccttt ttttaagaaa aaaccattaa agctccagaa
    19621 cacgatcatc cttgtcgttt gtttctccac attcgtttct ttgattgttt ctgccatatt
    19681 gatcaggaat tttattcttt cgatgaaccg atctagtgtg tcagataaaa tctctagcat
    19741 tgctaaaatc gttgccaatg ataaactcat ccaaaaaaag ctgcagactg gtgacccgac
    19801 acatgcgatt caaggaataa caaatgaaat catgattgca tcgaatttag attttatcgt
    19861 tgtcatggac cctgaaggca ttcgatattc tcacgcagac ccaagttaca tcggtcttcc
    19921 tttctcaagt catgaagatg tgaaaaaagt gattggagga caagaatttt tctctgaaaa
    19981 agaaggaatg ttagggttcg gcttccgcta tttcgtccct atttattatg atcaagagat
    20041 tattggtgca gtttgtgttg gcttaacaaa caacacgatt gacaatcaag tcaaagatgg
    20101 acaaaaaatg attgtttttt cattgattat tggacttagc gtaggcatca taggcgccgt
    20161 ttttcttgcc caaaaaatga aaaaagtact gcttggactt gaaccacaag aaatagcaga
    20221 acagttaagt gaaaaaacga ttatcgaaaa tgaagtagat gaaggaatct tagccatctc
    20281 ttctgataaa actatcctct tgatcaatac acctgcaaaa aacattttct accaaacaga
    20341 gcagctattg gatttcgaag taggaaaaaa atcagtgata atctatatga cgttttgttt
    20401 aaagagacga ttgagcatca aacgaccgtt cggactcaat ccatgtattt aaatgggata
    20461 gaaactattt ctagcgttac acctcttttt agcaatgacc gttttttagg agcagtcgca
    20521 actttacgaa atcgatcaga agtaatgaaa ttaatggagg agcttggggg gacgaaacaa
    20581 tatataaact ccatgagagc tcaaacccat gaattcatga ataaacttca tgtcatttct
    20641 ggtttgattg atttgaagaa gtatgaagaa gtcacccatt ttatccagca gctaaatcaa
    20701 aattataaaa aagagattgg ccaagtctca agtctgatca aagtacctgc aattgccggt
    20761 tttttattag gcaaaataaa cgaagccaaa gaacaatctg ttgaaatgct gttagaaagc
    20821 gattctttta tccctaaaat ggagatggat gactccatcc attcactttt gcaagtgtta
    20881 gggaacttac ttgataatgc aaaagaagcc gtgctacaaa aacatgaaag aaacggacag
    20941 gtccggattc atttaaacta tgacacagaa gctgaagtat tcatcgtgac cgtctgcgat
    21001 gacggtgtcg ggatatcaga agaaatctca gaaaaaatat ttacgctagg tttttcgacg
    21061 aagggaatca atcgtgggtt tggattgaat ctcatccatt caatcgtcaa acgccacggt
    21121 ggatttttag aattttccaa acaaacaaat ggcggtacaa tcgtctatct agaattacca
    21181 aaaaaggaag atcaaaatga tgacaaatgt cctgataatc gaagatgatc caatggttgc
    21241 agaattgaat cgtacttttg tggaaagcat ccctaatatg aacgtaatcg aaagtttcag
    21301 aaatgtagaa gaaggaaaaa aatatttcag acaaaaaaac gcagatctgc tgctgcttga
    21361 tgtatacatg cctggcgaaa gtggtatcca ttttttatct tggcttagac agcaaggaaa
    21421 tgatatccca gtgattttga tcactgctgc agatgatatc gaaaccataa agaatgtgat
    21481 ccgctacggt gccttagatt atttgatcaa accgttcact ttgcaacgtt ttcagctggc
    21541 gatcgaaaag tatcttgctt tctctcagac aatccaaacg actgaaaaag ccgatcagaa
    21601 attgatcgat caagtattca accacaccac tcccattcac gaaataccat cattcatcga
    21661 tttgcctaaa ggtctgtcaa aactgacttt aaaaaaaata agtgcattta ttctaaaaga
    21721 agatactatt ttttcaacaa aagaactggc tcaaaaaagc tcactgtcac gtatatccgt
    21781 caagaaatat ttgaattttt tagtagaaca agatatattg aacgaaagaa tcaaatattt
    21841 ggaaatcggc cggccgctaa cctgttatga attgacaaag aatgggcgga aaaagctcac
    21901 agattactgt tgagtcatcg aattatccca tacaaaatag tccaagtata cagaagtaac
    21961 aactgtttac ttggactatt tttaaacatt ttattgacga atatccatgt tttcttatct
    22021 taattgacgg gctttaggaa gagatacctc atttttcgtt tttccagttt ctattatttc
    22081 acgaaagttc tcgaaacttg tcgaaatcat atttgataat gcctcatctg tatttgaacc
    22141 tacatgcggg gttacaagaa ctctagggta catttctact aattgctgga tagcagggtc
    22201 tggaatcgtc tcccatggct tgaaggatcg gaaaaaaacc tctgtttcat ttgcaaaaac
    22261 atcggttgca aaaccagcta aatgattgct tttcaaagct cttaaaatag cttcattatc
    22321 ttgaagctct ccacgggctg tattaatcaa gatgctacct tttttcattt gagctaaaaa
    22381 tccttcattg atcatttgat cgttttcacc tgggatatga ggtacatgaa tactgacaat
    22441 atcgcttttg gctaataact cttcaagcga gtggaacgtc aatacttttt tagcagcttc
    22501 tgtctgatga atatcgtagc cgatcacttt ggctcctagt cccttaaaca aaacagcttc
    22561 cgtcaaccct atcctgcctg ttcctatgat ccctactgtg caatttctga tttcacgact
    22621 aaacatttgc tcatccactc gaaaatcttt gaaagatgtt cggatcgtcg tatacgcagt
    22681 atttctcaaa agcatcatgg caaaagtcaa agataactct gctatcgcat ttggcgaata
    22741 cgatggtaca cgggctactg tcataccaaa atcagctgcc gcttgtagat cgatatgatt
    22801 gactcccaca gtccgtgtaa aaacataacg aatcccatat tcctgcattt ttgcaagatt
    22861 ggtctcatct gctatacaat ttcccctcaa caatacagca tcatggtcct ttgctgacac
    22921 gatattgtca tgtgtcaaca gttcttcata aagactgaga tcataatggt aaatattcaa
    22981 tttttcaaaa aaatctatct cgttcggacg aacaccgtaa catgcgattc tcatactttc
    23041 ttcctccatt tcttatgaaa ataaacctat gccatgaatc atttgtaata caacgatcca
    23101 tacaggtgtc agtaccacag caaaaatagt tgacagtaag gatgcattgg aggctaaaag
    23161 tgcctcccta tcaaaactga tagcataggc tgctgccact gttgcagctg gtgtagccat
    23221 catgataacg attgttgcca gtgcttcaaa attgactggt agaatattcg ttgccgtcaa
    23281 aactgctaga atcacgatat tcaatgcagg tacaaatacc actttgacta gactgtaata
    23341 ccatgaagtt ttttcagatg cagctttttt gaagcttact tcacctaatg ttgcgccgat
    23401 tgctagccac gccaatggtg aacttaaacc agctaaataa tccatcggct gaaatagcca
    23461 cggtgcagtc tggtcaattc gcaaaaacgc tacttggctt atctctcctt ctgcacctgt
    23521 aactgacact tgtggcagat acccttggaa cagccaaatg aaaaggccgg caaaagtagc
    23581 gataatgatt ggattgacga acatcgcttt gatattttta gcttccatct tcaagccact
    23641 catttttatg tatccataag aatacaaaaa gattcggtag ccaatattga aaattgagga
    23701 atacatcacg ccgacaggac cataaatcgc actgacgata ggcgttccga aaaaggtcgt
    23761 agaaccaaag atcgtcagga cacgcaacgt tgtttgctta tcccctttat agcttaagaa
    23821 aaaaggtttt gaaactagaa taagaataat ataaataact aatccccaaa tcaagacatt
    23881 gattccttgc atcagtaatt ctgtattgat atcttgcatg aaagctcgaa atgccagtgc
    23941 tggcaaagcc actgttaaga cgactttcga tagaattttt ccaacagatt cagaaaaaat
    24001 cccctttttt ctacaaacaa accctaataa tataataaaa actgttgaag tgattgcact
    24061 gacaatcgac atatctgtca aagtcgatcg aaaaatgtca aataagttca tctttctcct
    24121 cctaattatg ttcatttatt cacaataaaa aaagctttta ttttgctaat acgtattaac
    24181 atttttaatt ttatctttac attgttactt attgaacaat aggaaattaa agaaactttt
    24241 gaaacttatg taaagtgatt tttactagaa cacaaaaaaa accttaaaac caaacttaag
    24301 aagtttagtt ttaaggttaa cttaaattat attatgcgtg gaaacgttcc acgccatcta
    24361 gataagttgc ttccaatgtc atatcagggt tcaatacgat aaagtctgca tcgcgtcctt
    24421 gagcgatttt tccacatgta tcatcgattt tacagctgat tgctggaatc agactagcca
    24481 tcatgactgc ttgttctggt gttgctaatc cccagtctac aacattttta attgcttctt
    24541 tcaatttcaa tatacttcca gctaagttgc cagattctag acgtgctgtt ccttctttta
    24601 ctactactgg aaattcgcct aaattgtaat ttccatcagg catcccaccg gccatcatac
    24661 agtctgtaat taatgcgaca tgatcatgtc ctgctttttc cattaggatt cccgcagcat
    24721 ttggatgtac atgatggcca tcacaaatca attcagaaaa gacatgttct aaagataata
    24781 acgcacccac catacctggt tcgcgatgat tcaatccacg cataccattg aaagcatgga
    24841 caaatacact tgcgcctgct tcaacagctt tttgcgcttc ttctagtgta gcattactgt
    24901 gtcctagaga aacaactact ccttcttcag tcacttgttt gacaaactct tctacacctt
    24961 gacgttccgg tgctaaagca atttttttga ttaaaccacc tgaagcttct tgccattcat
    25021 ggaaagtatc caaatcagga tccccgaaat aacttgggtt ttgtgcccct ttgtgttctt
    25081 ctgtgaagaa aggaccttca aaatagattc ctttgatttt agctcctggt gcttcctgat
    25141 acattttgcc gattgtctca gctacatctt ttaaacgttc tttgcttgac gtcaatgttg
    25201 ttggtaaaaa tgaagtcact ccacaagata acagaccttc agacatcact ttgatgcctt
    25261 ctgcatcatt atccattaca tcatgattca tatagccgtg aatatgtgta tctaccaaac
    25321 caggagcaat ccatttgccg ctttggtcaa tgatgttgac ttctccctca ggtagttctt
    25381 tggtgtattc accaaaaagt ccatcggtaa tttcaagata gcctgcatgt ttgacacctg
    25441 acgctaaaaa gaatttgtca gcatagataa aagttctcat tctattctct ccctttgttt
    25501 ttctacctct aaagtactct tatttagaga agaagtcaag aatggtctac accatttaca
    25561 aattttttga aatttgtttc acagcttgtg ctaagccttc atagaatgct gctctttctg
    25621 gttcttcttt acgcttgtat attaagcttt taagcacaaa taaatcattg aggtaatagt
    25681 agctattctt ctcttgagcc caatagattc cttgattcac ctgttctaac gcttcgtcga
    25741 tttcattttg atggaataag aaatttccat aattataaaa aatttgcgaa aattcacttt
    25801 ttgatcgttc atcagctgat tgatgcagca gttggatgct tcgactcaaa tagtagcgtg
    25861 cttcagccgt ttttcctgcc acaccatata tttttccgat acaactaatc agttgtattt
    25921 ctgtgtcaga aacatggatt ctttcttttt ggctagagta gcttaatgct tctttcaaat
    25981 aataaaggga ctgagagata ttttgacgca acgtgaattc gcaaacaccg agataataat
    26041 aatagcgttg aaagtcagtt gcttgataca gattttcaga aatatcagaa gattttagta
    26101 cttgttctaa cttccgataa tcacgttttt ggaaacaact atccaacagt tcaaataatt
    26161 tatcgtttgt ccgagtagtt tttcgagaga gattcatcac atgatcaatc gttaccccta
    26221 gccgttgaca aatctgcatc atcaccaata cattcggcag ttcctcatta ttttcgatcc
    26281 gacttaatac actttgtgaa caaatatcat gcgaaagcat tttttgcgtc attttttgtt
    26341 cttttcgaat ctctttaatg atcgttccaa aggactcgat taacgtttcc ataagtatcc
    26401 tccccaaaat atgcgtattc gcattctatt cgtattttac tttaggaagt cgcaaacttc
    26461 aagaaaagac ttgcaactaa ataatatact ttagttattt aagaaaactc cactagaaag
    26521 agagcctcag tgtgtttgtc tgtggccctc ctactgaaaa atttggtttt taaaatcatt
    26581 tttggcgata ggttgctagg aattctctca ttttcttagc tgtttgtttc aaatcatcca
    26641 ttttaggaag ataaacgatt cgaaaatgat ctggctggtt ccaattaaat ccaccaccat
    26701 gtacaagtag aatatgatgt tcatgtaaaa agtccaaaac gaatttttca tcatccaaaa
    26761 tattgaatcg ctttgtatca atttttggga atatataaaa agcagctttt ggttttacgg
    26821 ctgaaagacc aggaatatca ttgattgcat tatagatata ttctctttgt tcatagatcc
    26881 ttccgcctgg caggagcagc tcatcgacac tttgataacc gcctagcgcg gtttggataa
    26941 tttgctgaga caatacattg gaacacaaac gcatggagga caacatattc agcccttcta
    27001 tatagccttt gacgtgtgac ttatctccac ttaggaccat ccagcctact cgaaatcctg
    27061 ctacacgatg agatttggat agaccgttca gcgtaacaac gaacaaatca ggcgctaatg
    27121 tagcaatcgg aatatgttct agaccatcca tcactaagcg atcatagatt tcgtcggaat
    27181 aaataatcag gttattttgt cgagctactt caacgatttc ttctaataat tcttttggat
    27241 aaagtgcccc agtaggatta ttaggattaa tgataacaat agcttttgtc cgactcgtta
    27301 tttttgattt gatatcatca atatcaggat accattctgc ctcttcatcg caaatataat
    27361 gaacaggtgt gcctccagct aatgcaatag aagccgtcca caacggatag tccggcattg
    27421 gaaccagtac ttcatctcca ttgtccagca acccctgcat acacatcgtg atcaattcgc
    27481 tcactccgtt gccggtgtag atatcattga tcgtcacatt cggaaaatgt ttcagttggc
    27541 aatattgctc aattgctttt ctagcagaaa agatcccctt ggaatctgag tagccttctg
    27601 agtcacgggc attcatgatc aaatcacgaa tgacttcgtt tggtgcttca aatccaaaag
    27661 gtgcgggatt tcccgtgttc aattttaaaa tactaatgcc ctcttcttgc atccgctccg
    27721 cttcttctag aacgggaccg cgaacatcgt aactgacacc ttctaatttg ttggattttt
    27781 caaattctct catcacttag ccaatccctc atttcaaaaa gttagaactt tccaaatttt
    27841 ttgttattta ctatttcaat atcatactcc atcctagaaa attttgccac ttatttagga
    27901 aaaacgtaag tattaaaaaa acacaaacaa gcgttgagaa cttaattgtc atgatagtca
    27961 ttccatagat tcgctgccca atccattgca attccacaaa tgattcctag cataaaacca
    28021 agcaaaaaac gtccgaatgc aagtccaatc aatacaccta agatcattcc cagtcctgaa
    28081 aattctccgt catatttctc catcttaata agtcctccca tttttgagct tgacaactat
    28141 gtaaaacctc gctatcatta gtgtgttatt attacgcaga tgtgttggaa ttggcagaca
    28201 agcatgattg agggtcatgt gagcgttagc tcgtgtgggt tcgagtccca tcatctgcac
    28261 tacaactcgt gaagttaatt ttgcttcacg agtttttttg tttgaacgtt tctttatgcc
    28321 attatataca tatcactgta tcctttacaa aaagaacgta caatcatgta aacagcctga
    28381 ggtgagtata tgaaggtcgg aaacaagcta ctcgtagaaa cttgcaagtg ttaaaacaat
    28441 taatcgaaaa acgagtaaaa tccctcacct aatactaaag cgagggattt tttgtatatt
    28501 atctgtttat caccgttatt ataaaggtac aaataccaag cacggttaat ccaaattgca
    28561 taaattcatt tttttgtaca ctcatgcttt tcattagctc tttaactgcc attagtacta
    28621 agatggcgat aacaacataa agtatatagt acgtccgcat tccggaagcc catactgtgg
    28681 gagaaaatcc cataattaac cttgaacaaa atcccattat catcaaaata actaaaaaaa
    28741 tagaagtttt cttattgtca aaacttaaat aaattccaac aattaaacat agtaataatg
    28801 ccaagactac taaagtagct atccaagtac ctggataaaa aagtgacagt ttcgttccta
    28861 actctgtaaa gagattattc aggttactac tactccaaat cattgccctt ttatttccat
    28921 tgacgtaagt aaagctttga cccattgtat taccaaaata aataatcagg tttaagaaaa
    28981 acggtaatgc agtcaatata cgcacataat agttttgaca tttcctatat gttagaagga
    29041 aaattaagaa aaatagcaat aaaaataaga tattcatgtc taaaaaaaac ggctttccaa
    29101 atgatgaaat acctaaatct aacttattaa gaaagttgaa atttttatat tcaggaaacc
    29161 atttattaat ttcatgtgca gcacgtaatg cattccctgg agttgtcaaa gagaaaatta
    29221 attctgctaa gcttattatt gaaaatactg ataacttata attatatcgt ccattgacaa
    29281 tcaaatataa actaactata cttgttagaa caaaaaaaca ggcgttgact tgttcttgat
    29341 tagttaaaaa tatcaataaa ggaatactta cccaatatat ttttctattt atttcttctc
    29401 ctcttaagag ttgaaaaaac ggataaaaag ttagtaaact aaatgctact ggccactgat
    29461 agttcaaggt ggttgctctc caaccggttt cccccattac tgtcaatggt attaaacagt
    29521 atatagagca aaccaataat aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DAIGTA010000035        29107 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.035, whole genome shotgun sequence.
ACCESSION   DAIGTA010000035 DAIGTA010000000
VERSION     DAIGTA010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.035"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..1030)
                     /locus_tag="NOB43_001637"
     CDS             complement(<1..1030)
                     /locus_tag="NOB43_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0982496.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="NOB43_001638"
     CDS             complement(1112..1801)
                     /locus_tag="NOB43_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0982497.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOB43_001639"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOB43_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCI0982498.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="NOB43_001640"
     CDS             complement(2328..2831)
                     /locus_tag="NOB43_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCI0982499.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOB43_001641"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOB43_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCI0982500.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOB43_001642"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOB43_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCI0982501.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOB43_001643"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOB43_001643"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HCI0982502.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOB43_001644"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOB43_001644"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HCI0982503.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="NOB43_001645"
     CDS             complement(6443..7462)
                     /locus_tag="NOB43_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI0982504.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="NOB43_001646"
     CDS             complement(7635..8540)
                     /locus_tag="NOB43_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0982505.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOB43_001647"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOB43_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCI0982506.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOB43_001648"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOB43_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCI0982507.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOB43_001649"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOB43_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0982508.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="NOB43_001650"
     CDS             9753..10397
                     /locus_tag="NOB43_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0982509.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="NOB43_001651"
     CDS             complement(10453..10956)
                     /locus_tag="NOB43_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI0982510.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="NOB43_001652"
     CDS             11553..12518
                     /locus_tag="NOB43_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI0982511.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="NOB43_001653"
     CDS             complement(12617..13789)
                     /locus_tag="NOB43_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982512.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="NOB43_001654"
     CDS             complement(13776..14921)
                     /locus_tag="NOB43_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982513.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="NOB43_001655"
     CDS             complement(14935..15867)
                     /locus_tag="NOB43_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982514.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="NOB43_001656"
     CDS             15984..17063
                     /locus_tag="NOB43_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0982515.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="NOB43_001657"
     CDS             17060..17689
                     /locus_tag="NOB43_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0982516.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="NOB43_001658"
     CDS             complement(17799..18026)
                     /locus_tag="NOB43_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0982517.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="NOB43_001659"
     CDS             complement(18129..20717)
                     /locus_tag="NOB43_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HCI0982518.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="NOB43_001660"
     CDS             complement(20737..21396)
                     /locus_tag="NOB43_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0982519.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="NOB43_001661"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="NOB43_001661"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCI0982520.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="NOB43_001662"
     CDS             complement(22169..23035)
                     /locus_tag="NOB43_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0982521.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="NOB43_001663"
     CDS             23144..23785
                     /locus_tag="NOB43_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HCI0982522.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="NOB43_001664"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="NOB43_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HCI0982523.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="NOB43_001665"
     CDS             complement(25226..26125)
                     /locus_tag="NOB43_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0982524.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="NOB43_001666"
     CDS             complement(26127..26924)
                     /locus_tag="NOB43_001666"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HCI0982525.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="NOB43_001667"
     CDS             complement(26902..27606)
                     /locus_tag="NOB43_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HCI0982526.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="NOB43_001668"
     CDS             27737..28312
                     /locus_tag="NOB43_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HCI0982527.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="NOB43_001669"
     CDS             28430..29107
                     /locus_tag="NOB43_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI0982528.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8563 a         6169 c         5232 g         9143 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaa
//
LOCUS       DAIGTA010000036        28082 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.036, whole genome shotgun sequence.
ACCESSION   DAIGTA010000036 DAIGTA010000000
VERSION     DAIGTA010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.036"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..1376
                     /locus_tag="NOB43_001670"
     CDS             <1..1376
                     /locus_tag="NOB43_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0982529.1"
                     /translation="TVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVT
                     YPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTV
                     TDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTT
                     DLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDV
                     TVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGN
                     KKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTL
                     PDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKN
                     GSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYK
                     NRKKENE"
     gene            1510..2853
                     /locus_tag="NOB43_001671"
     CDS             1510..2853
                     /locus_tag="NOB43_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0982530.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2965..4416
                     /locus_tag="NOB43_001672"
     CDS             2965..4416
                     /locus_tag="NOB43_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HCI0982531.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4765..5397
                     /locus_tag="NOB43_001673"
     CDS             4765..5397
                     /locus_tag="NOB43_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HCI0982532.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5985..7424
                     /locus_tag="NOB43_001674"
     CDS             5985..7424
                     /locus_tag="NOB43_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0982533.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7719..7937
                     /locus_tag="NOB43_001675"
                     /pseudo
     CDS             7719..7937
                     /locus_tag="NOB43_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8186..8401
                     /locus_tag="NOB43_001676"
     CDS             8186..8401
                     /locus_tag="NOB43_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982534.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8618..8874)
                     /locus_tag="NOB43_001677"
                     /pseudo
     CDS             complement(8618..8874)
                     /locus_tag="NOB43_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9061..9972)
                     /locus_tag="NOB43_001678"
     CDS             complement(9061..9972)
                     /locus_tag="NOB43_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0982535.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9991..10995)
                     /locus_tag="NOB43_001679"
     CDS             complement(9991..10995)
                     /locus_tag="NOB43_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCI0982536.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNRSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10992..13115)
                     /locus_tag="NOB43_001680"
     CDS             complement(10992..13115)
                     /locus_tag="NOB43_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0982537.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13120..15567)
                     /locus_tag="NOB43_001681"
     CDS             complement(13120..15567)
                     /locus_tag="NOB43_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0982538.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15554..15943)
                     /locus_tag="NOB43_001682"
     CDS             complement(15554..15943)
                     /locus_tag="NOB43_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0982539.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(16003..16506)
                     /locus_tag="NOB43_001683"
     CDS             complement(16003..16506)
                     /locus_tag="NOB43_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCI0982540.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16519..16740)
                     /locus_tag="NOB43_001684"
     CDS             complement(16519..16740)
                     /locus_tag="NOB43_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982541.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(16745..16882)
                     /locus_tag="NOB43_001685"
     CDS             complement(16745..16882)
                     /locus_tag="NOB43_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HCI0982542.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(16879..18063)
                     /locus_tag="NOB43_001686"
     CDS             complement(16879..18063)
                     /locus_tag="NOB43_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0982543.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(18322..18612)
                     /locus_tag="NOB43_001687"
     CDS             complement(18322..18612)
                     /locus_tag="NOB43_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982544.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(18602..19744)
                     /gene="dcm"
                     /locus_tag="NOB43_001688"
                     /pseudo
     CDS             complement(18602..19744)
                     /gene="dcm"
                     /locus_tag="NOB43_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(19820..19984)
                     /locus_tag="NOB43_001689"
     CDS             complement(19820..19984)
                     /locus_tag="NOB43_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982545.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(19977..20651)
                     /locus_tag="NOB43_001690"
     CDS             complement(19977..20651)
                     /locus_tag="NOB43_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCI0982546.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(20729..22069)
                     /locus_tag="NOB43_001691"
     CDS             complement(20729..22069)
                     /locus_tag="NOB43_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCI0982547.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(22152..22487)
                     /locus_tag="NOB43_001692"
     CDS             complement(22152..22487)
                     /locus_tag="NOB43_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HCI0982548.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(22497..22871)
                     /locus_tag="NOB43_001693"
     CDS             complement(22497..22871)
                     /locus_tag="NOB43_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0982549.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(22884..23198)
                     /locus_tag="NOB43_001694"
     CDS             complement(22884..23198)
                     /locus_tag="NOB43_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0982550.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(23311..26538)
                     /gene="fss3"
                     /locus_tag="NOB43_001695"
     CDS             complement(23311..26538)
                     /gene="fss3"
                     /locus_tag="NOB43_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HCI0982551.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(26955..>28082)
                     /locus_tag="NOB43_001696"
     CDS             complement(26955..>28082)
                     /locus_tag="NOB43_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0982552.1"
                     /translation="YSVRLYVRKDENGKQEYYVKKGFKTEKEAKLHEARKKVEIEDTG
                     YHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFGNKSISKITPVHCQ
                     NAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPKREKKENENYFSLE
                     ELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFEEQLMYVRKSYATI
                     RNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQARELLQFGINTNTK
                     NQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFRHTHATLLLEGGAS
                     IKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
BASE COUNT         8560 a         5597 c         4982 g         8943 t
ORIGIN      
        1 gcacagtaga tctaacagat aatgttacta acttgccagc gttaccagaa ggaacaacag
       61 taacagatgt tactcccggc ggtacaattg ataccaacac accaggtaat tacgaaggtg
      121 tcattgaagt aacgtatcca gacggtacga aagatacggt gaaagttcca gtagaagtga
      181 cagacaatcg ttctgacgcc gataaatatg aaccaacagt agaaggcgaa aaagtagaaa
      241 ttggaggcac agtagattta acagataatg ttactaactt gccagcgtta ccagaaggaa
      301 caacagtaac agatgttact cccggcggta caattgatac caacacacca ggcaattatg
      361 aaggtgtcat tgaagtaacg tatccagacg gtacgaaaga tacggtgaaa gttccagtag
      421 aagtgacaga caatcgttct aatgcagata aatacaatcc tgaaggacaa aaagtgacta
      481 cagacttaaa taaagagcca gatgcatctg agggaattaa gaacaaagaa gatttaccaa
      541 aaggaactac ttatgcttgg aaagagaaag tagatgttag cacagctgga aataaaaaag
      601 gtactattgt agtgacatat ccagatggat catctgatga agttgaagta gacgttacag
      661 tgacagatac tcgttccgat gcagataaat ataatcctga aggacaaaaa gtgactacag
      721 acttaaataa agagccagat gcatctgagg gaattaagaa caaagaagat ctaccaaaag
      781 gaactactta tacttggaaa gaaaaagtag atgttagtac agctggaaac aaaaaaggta
      841 ctgtagtagt aacatatcca gatggatcta aagaagaagt agaagttact atttctgtag
      901 tagataaaaa agcaccgaat aaacctcaag ttgatcctat tacagagggt gaccaaattg
      961 ttactggtaa aactgaacca aatgcagagg tgacagttac attaccagac ggaagtcaac
     1021 accatgggac agctgataaa aatggtaatt ttacagttaa agttcctaaa ttagaggcag
     1081 ggacaaaagt gatagtaact gcaactgatg aatctggtaa tactagtgaa cctactaatg
     1141 tagttgtttc ttccaacaaa aaagacagtg gaaaaaacgg tagtaaaggt agtaagactg
     1201 acaatcaagg tagcaacagc aatcaagaca aaaatagagg caaaagccag tcctcaaaag
     1261 tttttcctaa gacgggagag agtgacagta atatctttac tattagcggt ggtttaatac
     1321 tgttaggaac gttaggatta ttagggtata aaaatcgaaa aaaagagaat gaatagaaaa
     1381 tcaatttctt aagtcttctc tgagaagagg aagaatcttt ttcttcctct ttttgctttt
     1441 ttatgatggg aaataagtgt tagttaaaga tgaatatact ttttatagaa aggaaaagaa
     1501 tgtaattaag tggaaaaaat agtaattatt ggttcaaacc attcagggct agccgcagct
     1561 cgatttctaa acttaagcga ttcaaattat gaagttattc taatcgataa aaaatcagaa
     1621 attagttact tggaatgtgg gacatcgtta tttataaaag gagaagtaag taatttagaa
     1681 gatctttttt atcaaaatag aatgacacta aattctgaga taaaaaagtt atttctagag
     1741 acagaagttg acaaaattga tattcaaaat aaaaagatta gttgtgtaaa aaaagatggt
     1801 acaagattct ctcaagaata tgacaaagtt atattagcta caggttcaaa gcaaattatg
     1861 ctagatatac cggggaataa tttagctaat attttttcga taaagaattt tccaaatgca
     1921 aaagagattt ttaaagcttt ggatgatagt actattaaaa aagtaggaat tattggagca
     1981 ggatatattg gagttgaaat tgctgaagcc ataagaaaaa gagggaaaga agtatatctt
     2041 ttcgatgttg cagatagagt gttgtcgact tattacgacc gtagtttttc agataaagtt
     2101 gaagaaatac tatcaaaaaa tggaatacat ctttgtctat cagaaagtcc taaaaaatat
     2161 ttaggaagaa aaaagattga aaaaatagtc actacaagtg gtacccaata ctctatggat
     2221 atggtcgtac aagctatagg atttctatct aatagtccaa ttggggaaaa ggaactcttg
     2281 agagatgtta gtggagcata tctaactaat gaataccagc aaacaaatat aaaagatata
     2341 tatgctattg gggattgtgc tacaactttt tttacgtcca ttaatagaag tagtgttgat
     2401 ttttctattt ctaatgctct aagaacagct tatattgcaa ctcaacatat taacaatcaa
     2461 gattttacac cttctggttc ccaatttaca aatggctttt ctatatttaa ttacaatttt
     2521 tacgcagcag gtttgaattt aaaaacagca cgattattaa gtgagtctat agattatata
     2581 gaaatagaag atttcattag acctgctttt ttgagaaaaa atagtcgtgt aaaattaaga
     2641 attagctttg aaaaaaatac aaagagaata gtaggtgtac aactttgtag tcaagaagat
     2701 ttatctggac tattatcaat gttttctctt gctatagaag aacaaattac attagacaaa
     2761 ttgaaaatgt tagattattt atttcatcct agttttagcc aaccctataa ttttatttta
     2821 aaggcagtaa caggattaaa cattgaaaca taatcgttac taaatgaaat caagaaatat
     2881 actgtattac tcaattcatt gaaaatattt atcataattt ttaatagaaa acactattaa
     2941 agagaaaaaa gagaggtaaa tcaaatgaaa aaatctttaa aacttgcatc agcagttata
     3001 ttaatgtccc aactccttat agcaacacct ttccatgtgt tggcaagcga aaattcaaca
     3061 tacaaaattg caaaagaaag aaccgagacg actgaaatga gtaattccga tgtaacagca
     3121 gagagtagtg aacttttgac aacttcatca agtgaaagta gtacgacttc aaatgccgag
     3181 tcttcaacaa cttcatcaag tgaaagtagt acgacttcaa atgccgagtc ttcaacaact
     3241 tcatcaagtg aaagtagtac gacttcaaat gccgagtctt caacaacttc gtcaagtgaa
     3301 agtagtacga tttcaagtac cgaatcttca acaacttcaa gtagtacaag tgaaataact
     3361 tcttcgaaag tgacaaaacc aaaccatata gaatcttcaa aaaaggaagc gccaaaaacg
     3421 gaaggacaaa caaaaacttt ttcgacacca cagcaaatag aatcaacaga atctttccaa
     3481 tcacaaccaa tactatctgg taatgaagaa attcattttg acaaaaatga atctgtagaa
     3541 aattttatta tgaaaattgg tgagtctgcg agaaaaattg gtcagaaata tgatttatat
     3601 gcttctgtta tgattgcaca agcgatctta gaatctgcca gtggtcaaag ccagttagct
     3661 caggcaccga attacaattt atttgggata aaaggaactt ataatggaaa ctttgtcatt
     3721 atggtaacaa acgaagattt gggtaatgga acgctttata cgacccaatc aaaatttaga
     3781 gtgtatgaaa actatgagga aagctttgaa gattatgcca aattattaac taagggaatt
     3841 agtggaaata aagattttta tgcaggagca ttaaaagcta atagtaaaac atatcgagaa
     3901 gcaactaaat tccttacagg acggtatgca acagatacac aatactattt gaagctaaat
     3961 gaattaatta aaacctacga tttaaccaac tatgataaag aagttaaagg tccacaaatg
     4021 agtaagactg gataccaagt gcctattcat aattattcaa taaccagttt gtttggaaat
     4081 cgtggaaatg aatttcaccg aggacttgat atggcagcta cacagggtga gccgattcat
     4141 gcagttaaag ctggtaaggt tgttaaagca gagtttcact actcttgggg aaattacgtg
     4201 gtgatacaac acgaagatgg atcaaccgcg ttatatgctc accagcaaca atacctagta
     4261 aaaactggag ataatgtttt gcaaggacaa ataattggct atgtaggaag tactgggaat
     4321 agtactggcc cacaccttca tttggaaatt tgcaaagata gtagtctttc tcagagcatg
     4381 ttagttgatc cgaaaacctt attattcgga gactaaaaaa ggtaatcaat ctgacaaagt
     4441 aacaagaaaa tggttggatt cttagacctt tgatcaggat attgagactg gaattgatat
     4501 ctcgattacg atgggtttga caaataaaac aagtccatta tcgaatatcg agtgtattat
     4561 tgccgtcttt atgctcatat tttgagcagg tttcactaga tgaaaacaat ttatctatct
     4621 tgaggatttc gtgtacgtat cgttcagtct tgtattgtaa attagtcata aaatcagact
     4681 aagaaaaatt ggaaatattt ttttctgatt tattaaaagt taattgaaat tatatggtac
     4741 ttctttcttg ggagggtagg tgcagtgaag gaaagatatg gtcaccttac tgttgttgag
     4801 gagattactc ataatggata taaaaaatat cgttgcctat gtgactgtgg gaatgaaacg
     4861 attgtatatc gatcaaactt actatcaggt agaaccaaaa gttgtggatg tggaaattat
     4921 aaaaataggc ataaatataa aaatttgaca aataaaactt ttggtaagtt agttgcaatc
     4981 aagccaacta aactgcgaag tgaaggaact gttgtttggg aatgtcaatg tctgtgtggg
     5041 agaaaaaagt tagtatcggc aaagcgactt ctaaaaggtg atgtaaaaag ctgtggatgt
     5101 ttgaaatcaa aaaagcatca cattgaaaat aaaaaattcg gattacttac tgcaaagtat
     5161 cctttggaca ataactgttc atggaaaaca aaatgggttt gtcattgtga gtgtggcagt
     5221 atgtgtgaga taagttatag taacttattt tttggacata ctcaaagttg tggatgttta
     5281 aaaaggcaag aaacaaggac atgtgttgaa gggacagtaa tagagtgtct aacgtcaaaa
     5341 ttaccgaaaa ataatacaag tggtgttaag ggagtttatc gttctaaaga gaaatagatt
     5401 gcgtatataa ctttaaaaaa aaagaggtac tatttaggat cgtatgattc tattaagagt
     5461 gcagctcaag ctagaaaaga tgctgaaaat aaattgtttc aacctttgat tgacaaatat
     5521 cgaggtaatc attaattatt gtggataata attaacagtg atatataaac atctataata
     5581 tattattcat actattgata tttagtataa tcctatggaa ttgaatatca tagcaatgta
     5641 tttgaaaagc aaattggaaa acaaataggt gcaacaccat aaatatgaaa aaattgggaa
     5701 aaagtagaat ggaaatttgc ttacgtctca cgagatagct cacactatta atctgaagaa
     5761 caatgaagtc gacttttaga aattgctaga agaaagtaaa gcgaattatc actagttact
     5821 atagagtaag ttcaaataaa gcatctccaa cttacatggt tacatgagga tatcaaatcg
     5881 aaattactca agcttcctat ggctagagtc gcgagaagtt gttgggcagt agacataggt
     5941 tatattgttc ttagctacac gatcattaga aaggaaatcc tattatgtat agttatcaag
     6001 aagatgcaaa agtccaaaaa aatcgctggt ggattttgat tgctatatct atgtttacct
     6061 tcatgtccac attggatggc agtattgtca atattgcact acctaccatc tcagatgata
     6121 tgggcatacc aatgaatcaa gcggaatggg tagtgtccgt ttatctgatg attgtctgtt
     6181 cttgtttgtt gctgtttggt aaaattggcg atagccgtgg gaaaatcaaa gtatttcgga
     6241 ttggtacgct gatctttgtc ttgggatcgc tgttgtgtgg gttcaatcat tcgctaggta
     6301 ttttattgtt cgcacgggtg gtacaagcca ttggtgctag tatgactatg gctacaaatg
     6361 ccggaatcat cacggaagtc tttcccatac atgaacgtgg tcgggcattg ggagcaatag
     6421 gtgcgtttgt ttcattaggc tcgattgctg gaccaggtct tggcggcttg attttgtccc
     6481 aattttcttg ggcgtacatt ttttggatca atgtaccggt gggaatcgta acgatgttga
     6541 ttgctgaaaa attcttacca aaagatatca ccatgagcgg ccatacaatc gatggagggg
     6601 gctttgctgc cattgcggct acgattatca gcttttttgg agcaatcttt ttggggcaag
     6661 aaagtggctt tttccatcca gtcccccttg tactgttcgt aatttcagtg attgcctttg
     6721 tcagcttttt aaaagttgaa aagaaagcag cctctccatt gatttctttc ggtattttta
     6781 agaacaagat ttttaccatg agcttgatta cagccttgtt gattttttct tccaacttct
     6841 ttgtcaatgt agtgattcct ttttatctgc aaaatgctcg cgggttgagt cctagctatg
     6901 ctgggctgtt gatgatggtc tttcctttga tgatggtcgt cggggcgcct ttaagcggct
     6961 acctgaccga ccgggttggc ccggagattt tggtattagt aggcttgggc ttattgtcgg
     7021 taacccaggt catgtatatg tttttgtcag tggactctcc tttgtggcta tacattgtcg
     7081 ctactgccat catgggtgcc ggcaatgcct tgttccagtc ccccaataat acgatggtta
     7141 tgagctcggt cactatcgaa aacttgggac tggcaggctc gatgaattcc tttgcccgaa
     7201 atttggggat ggtcagcggg atttcgcttt ctacgacggt cttatatcaa gcgatgtctg
     7261 ctaagatggg ccagcaagta actaactata tcgcaaatcg gccggatgtc tttttatatg
     7321 gaatgaagat taccttttta ggcagctttg ttttgtgttt tgttgccttt ttcctgacta
     7381 tctggcgtat caaaaaacaa ggaggtattc agaaaaatgt ctgaaaaaac cactgttgaa
     7441 gaatttttgg aggcctgcgt atgggtgagt gggatttcca tggatgatgg aagatgaagt
     7501 gaacttctaa aagccgaaaa actcaagtat tatcttcaaa atactagtgc tcaatgagat
     7561 gcttgatttg atcacaagaa gactgcgaaa gccgctggca accgcaagct aggtatccca
     7621 ccgatggact acgttttaga ggctactggt tatgaatacg gagccaacgc tctcatctgc
     7681 ataagaatac atcacccaga ttatgtaaag attttcgata cttctgtcaa aaaatcatta
     7741 agatagataa atgatttccg tctagtcaaa ttggttcaga atgtagacac acagatggta
     7801 agaagtcact cacaattcga gaatggactt gtcctatttg ccgtatacat cataatcgaa
     7861 acgtcaacga tagtatcaat attttgacca agggctatga atacaagcat tgccttagaa
     7921 aacatcaaga accttaggaa caacggggat agcttggtta ataagagata ccgctgttta
     7981 ggcttgcaag tatactcttt tatcaagaat tccgtggctt tagtcatgag aggcttaata
     8041 ctatgaaaat tttctttagc atttttgatt taggttcctt ttctaattat aataagatga
     8101 ccactacagt aacctactga aatatataaa cagccactgt agtaccattt tcaaagtagt
     8161 ctatgagagg agaatcttca ttcttatgaa cgctggaatt gcggatatga atttaataaa
     8221 aaaaaccctt aatgatttta cttccaattc aatatcaaaa ggtactggta tcaatttaag
     8281 cacaataaaa aagctgaaaa gtggtgaaag atcagtggaa aagctgaatc ttttagatgc
     8341 tataaaaata acggaatttg ctatgaaaaa tggaaaagct gagattgaaa tatggagata
     8401 attatcgtct agtgaattac ttgccactta gctgaattta acgatccttg gtgcttgaag
     8461 ggggagattc ttgggaatag agcatacttg caagcctatg tctttactaa caacgatatc
     8521 tcttattaac caagctatcc ccgtagttct aaggctttta cttttatcta agcaataatc
     8581 gtattcaaag gaaatttttg acccttagaa agtctcattt tatcagacgt gagcttaggc
     8641 attgctgaat tttgttaatt cggttttagg ttgtgctttg agcataatat gaaagtattc
     8701 tttatcacga tttcattcat ctaaggtaat gtgatgtgat tctgaaattc tttcaaaggc
     8761 agtttttgca taagctgaca ttacatcatc aatgacatgt ttacaatgtt tcactactaa
     8821 aataaggggg taaccaagaa gaaaaactga atgattattt gtatctaatt ccatggtata
     8881 tcaaccattt cctatataga ctgattatga catggattaa aataaaaagg cactatgtct
     8941 taattgtcgg ttttcgagtt accgaatggc attcatcacc cacctataga ggatgggcga
     9001 cttctgcctg aaataagtta cactacttat aacttctaat aaaattagat tgagtcatta
     9061 ttatttaaca tcaacgattt tccagtttcc atttttttgt aatactaatt tgtactgaaa
     9121 gtagctagtg gtttttgata cattatcaag gtattttatc tttgtactca ctagaaaatt
     9181 ttttccgttt tgtagataaa ctggattctc taactccgaa aactttaagt caatattgat
     9241 tggtcgcatc gcaccatttt caacataata ctccaattct ttttcagaag ctgatggata
     9301 aagtttaaaa aatgtttcta aaaaatcggt gatttcttcc gttgttttgg catcaatttc
     9361 tgaatcgttt tctacttgtt ttgcttcata ttttgccttg tctggctttc caatcattgt
     9421 tggcaaacta gttactaaat gattcctgtt ttcatcttca aagattgtca ctcgatatgc
     9481 agaagaaatt gattgcgtct tttttccctc tgtaatatgt tgctccacta aaaatgaaac
     9541 gacaaattct tccgagtgtt tttcaacatc tagaattttt acagattgaa cttcggaact
     9601 cgtgggaata tctgctcgaa ccatatcttg gattaaagcg agaccgtttt ctgtaaggta
     9661 ctgttcgaga ttactcattc tcttttcaat tgcttctttg ttatttttcc atgaaaaata
     9721 ttctttcgca aaatcctctg taaaactttc aacgccagaa gtattcacta ccttctcttt
     9781 tataaccact ttttcatgag ttgtatgttg atcaatggcg gtgaaatttt tataaacgcc
     9841 aaaagcaaga ctacaagaca ataaaagcca aagggcaagc accatttttc gatgcttacc
     9901 cacggataca actcgttctt ttttcttttt tgggctcttt tccttttgat tccgttcaat
     9961 ttttatcttc attctttttc ctcttttctc ttatttgtat cggccagctc cgataagatg
    10021 ctgccgccaa tagttttccg ttagattcgt ccaccccact ggatctcctg catgaaacat
    10081 gcgattctcc cctgcgtaaa tgcccacatg ggtcacataa gtaccggcat cataggttga
    10141 atgaaagaaa actaaatcac ctggtttggc atcttttaga tcaatatgag tcatggcatc
    10201 atattgatcc tgagccaccc gaggaagttt caggtcaact ttggcataac accattgggt
    10261 caagccacta caatcaaacc ccgtttctgg acttgagcca ccaaacacat aggccgttcc
    10321 ttcatactta aatgcctcat caaaaatttc ttggactatt ttgtcatcaa actgagttgt
    10381 agttaggtat tgcttcacta ataaacagta aaacatattg ccataattat accgccaccc
    10441 accattttcc ttaatcgcga ttgggttggg gtaatcgact ttttgaccac ctgatttttc
    10501 ctttgaaaaa gattcagcta aagcaaaact atgcttcttc ccgtttttcc cgacatgatc
    10561 tagatacccg ccaccatagt tataggcctg aataatacta tcttgatcac accctagttc
    10621 tttggaacgc ttaaccaaag acgcaaaata gagacagcct tgtttgatgg atgcctcggt
    10681 acttaatgaa ttaggtggta atccggctga ctcagaactt tgcataacgt cttccattgt
    10741 gccaccagat tccacttgaa taatcgccaa aagaattgga atatactctg ttatatccga
    10801 ttctttggca tacttttcca ccattgcacg gtgtttcaat acttcttctg agacactagt
    10861 tccgccagga gaagtgccag aactacgatt tccctcactg tcttcaccaa acaacaaacc
    10921 cacacacatc aaaataccca taaaagagat ggtcagaaaa gttaatgaaa taacacccac
    10981 tttcttcaag ttcatttttt ctcacctgac cttgattttg gacgatggtt cattcttttt
    11041 tgtacttttt gattggtctg ctttggcaga gtggacctct gtttcacttg ttggaaagaa
    11101 tttttcttac ttgctgattg gcttttccct tttgaaatga tttcttgact agttagtttt
    11161 cgtttgattt cgggattcag atttgctctc acaatccgct ttggtgcttc ttttttcagc
    11221 atcatatctt tctgaggttg agctgcttta tctattggaa tattcgccct tctttttccc
    11281 tgacgatttg ttgcttcact cagtatcttg cgtttttcgt ccattttcgc atttcttcgt
    11341 tgtcgttgtt tttctcgcaa atccactcga tccgcttttt cttggaacag tccgcgcttg
    11401 aattcttctg gtgctttttt cgacttttcg attcctttat ggagattgta tttcaaattc
    11461 gttggcgtat tccttacctg atcctttact tgtttagtct tatctttcac caaagcttgg
    11521 gtatccaaaa ctttgccgat ttttctccca gccaaattca ttcgggattg tttcttatta
    11581 tttgaaactg gattctcctt agttaagtca gatagtattt cgtgatcgtt cggtaatcgt
    11641 gaattctttc gtagagaaga accggatggc ttaaatttgg attttgattg ttcctttgcc
    11701 aacttatttc cgactgctgc accaccacca aaagccaaag ctcgtcccac atttcgattg
    11761 agttgccgca attttcgatt cattaacatt tgcggttttc gcatgacgcg tcttcccatt
    11821 gactggctat cattactctg gaggttgaac atactcataa tgtcgcccaa tttgaaatag
    11881 ataccggcaa aggtcacaat ttgcagaaaa gcaaccatga aaaatggata ggttgccgaa
    11941 atattgaaaa acatcgtgga gatgctaaat gcagtcgtaa tcaccaaagt aacacccgct
    12001 cgcatcataa tcgtattgaa taaacgaata atcgccttct ttcctaaact ttcataagtc
    12061 ggcaacatgg acaataagaa actaattggc agaaacatcg caaagataat gaagagaatt
    12121 tgcgagaaca acataatccc tgttagaaga aaaacaaaga aggaaatgcc aatattgaac
    12181 aataccaaaa agaccacggt ccctaaacgg ttcatggtct tggtaatact gagattcgca
    12241 ttgtcattgt cttcaatctc tgccttgacc gcttcttccc gatctttgcc tttgttttca
    12301 tctggactca cagatagaat cttgttgacc cggtcttcac caatttcttc tatgttggaa
    12361 tcatcaaatt gcagtagtaa ccaaggttgt tggacttgaa tcgaaaacaa actatcccga
    12421 atcaaatcca cactatcttt tccttggctt tctgaattgg gtacaacgat ctcggttcca
    12481 agggtaaggg ccgcttcact aacatctgag ctaaagtcat tgatttttgt gatataggta
    12541 ggcgcataag caatgaacga acccgatagt agaaaaatca tcacaaaatt aatcacggct
    12601 cgaactgctt tcgtggtttc tcgttttaat aatccggtat acgccacata cacccccaga
    12661 gctaaaatca tcaataatag aaacccaaaa taaaatccgg aggtctggag tccattttca
    12721 gtaataccag ccaatgtttg gatattcttt ccaatacttt cagccgtatc cgaaatgaaa
    12781 tctaatttgt aagcctcttg aaccacataa cccgtggcgt tcgacaaata caaactcacc
    12841 gtccaaatga aattagtaat ggcataaaga ccatacatca cgcttttccc taagccatca
    12901 ccccaattcc aaggcaacca atcccaagag ctatccacaa agaaatctag ttgatagttg
    12961 ttcagtgaat atttggaata tagatttcct gcttcaactg tatcatcaac tagccctgtc
    13021 gcctcggcta ccgtaccaac taaactcaat agaactatca gagtgagtat gctaataaaa
    13081 acgattccca caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac
    13141 aggtggacgg gtatcaaagg catggaagag ttcttcaaag actggatgta cctgaaccac
    13201 gcctacccga ccatacaaat cctgcatcaa gcattggcca ttttccaaat ctcgtaggcg
    13261 tttttgattg ctttcatctt ctcgatccaa gccaaagaat tccaaggttt tcttgatttc
    13321 atgaatatcg gtactgcgaa acgcaaactt caacccgata ttattcttca agcgttcatc
    13381 cagtaaatca tcactatttt gcgtgacaaa gtaaaccccg gcattcatag cccgcccagc
    13441 acgaacgagc ttattcgata atgttttccc ttgcgctact tgaagaaaac tccacgcctc
    13501 atctaagtct acaattttga agatttctcg attactatgg ataaagtcca aggcaaaagt
    13561 ggaaatgacg attagcatgg aaacactaag caattccatg gtggtatatt cttcaaaagt
    13621 ggtttctgca tctggtaaaa ccaaatccgc tacttgaatg atatttaact gcctatctaa
    13681 actaatcgac tgggtaatcg aaccatctga gaaaagcaaa tgggcaaaat cataatcggt
    13741 aaaggactcg atgtgatccg cgatattttc cgcaactggt gagccttctt ttcgaagctc
    13801 attaattact tgtaataatc cccgttgatt gctttgggta accgtccgaa tggccttacg
    13861 caacactgga aacttctccc catctcgact agaaattcct gttaaaaagg tcagaatatc
    13921 aattgctaga ctttcagaat ccttcttttt ctccataatc acataaggat caagtaatcc
    13981 ttgatttttt ggcttactag ttaagttgag aatattgatt tcatccgcaa tttctggcaa
    14041 ggtttctttc cagccacccc gttccccttt tggatcgaca atcacagctt gtccaccaaa
    14101 aaggacggcg taataaacta agagattgtt actaaaggac tttccgccac cgagtgaacc
    14161 gaggaatgcc gctgctagcg cattggtaac tgaacccttg accccttgtg aggccaatgc
    14221 cggtttcagg taaacattgc gccccgtatc tacgttataa ccaaagtaaa tgccttccaa
    14281 ctcccctaac atctgagtgg cgccaaaacc aagtccggcg agaaaatcag acgtaacata
    14341 ctggatataa tcattcatgt atcgcttact agaaggtaag aattcttcat gtagccccat
    14401 catatcgcca aaaggccgga ctagttttac attggtatca tcataaaaat ctagcacttc
    14461 atcacaccgg cgctttagtt catctactga ttcggcactt actcgaacca catagctcag
    14521 tttgtacatg gattctttgg actgatccaa ggtagtttcc aattcatcta cggaatccaa
    14581 tgcatctaag acattggaat ttgtttcatt gtcagattga taggcatggt tgtccaagtc
    14641 ttttaattcc tttttcttat tgcgaacggt agcaagtgcc tttttgttcg tcacaatctc
    14701 cacattcata ctagtgtcaa ttgggaatgt aaattgttgt tgctggtaat agaaaagttc
    14761 tgaggaggga aactccattt cccccacaat tgtattaatt gttaagtacg ctacatatga
    14821 ttcatgattc tcatgttcca tgcataagta ccggggcttt tcttcaatca aacaacgact
    14881 gggacgtaat aagtcgtaac gtttcaccaa agtttccgac ttcagctttt tctttggtag
    14941 ctgaaattca tattcttcaa atggtgtacc cttttcgcca tagatatgtt caatcaaata
    15001 catcagatca ctcggtgtga ctcgtctgac tttaaatctt cgagccaatt tactttccat
    15061 tagtttttca agcttggtat atcggcgaat ttcttcattg gataaggaaa caaaatcgcc
    15121 catcaaatga tgattcactc catagacaaa ttcttgaaag ccggagaaga aagatttctt
    15181 gagattcttt agattgacct cttcatctgt cgcaatcagt ttgaagccaa taaaaaagcg
    15241 ataatcaatc tgactatcgc caatcatgga tactaatgcc tctgtctgta aatcaattcg
    15301 ttgtttcgct acttctgtta atcgcccggt aatttccttt tttgatcgtt cttgcgtggc
    15361 acgaatacta ctttctgtgg caatttgtaa ggcatgaatc ttgccttcac gattttgcgc
    15421 aatcaattga cgaaagttat cgtggacttg atatttctgt tcaggtgaca aaaaggagta
    15481 attgtaaggt attaactcat agtaggcaaa acattctccc tcttgattaa agacaagatt
    15541 attttcaata tacttaatcg ggtacatagt tcacactcct taccagagta atgggttcgt
    15601 cccatcgttt cttctgttct ttgactttct ttcctgcgaa agtgacctta aatcgtaagt
    15661 gatagctaat aaaagatcgt aaaaatccca atggtttctt accgtcaaac gttttttgcg
    15721 acatgaacca agtaactgcc accggtatac ctaagtattt taaaaaggcc ccctctatca
    15781 tagatagtgg aggcacatgg gcaaatacga tgacaaacag caaggataaa acaaaccaag
    15841 ccatctggtt aaaagtcaca ggaaaaggca gttgaaagtc attaattgca taaatgacct
    15901 tttcaactgc ccaaatactg gtgtagcttt ttattttctt catcaaatca ttcctttaaa
    15961 aagaaggata gtttagaaat caactaccct tcaataattt tgttaatatg gatactcaaa
    16021 aacacctcga ctcgttacca aataattgcc tccaatctcc aagtctctac cacacgcatc
    16081 aaaatcaata tacgtcttca agtgttctgg tacttctcca aaatcaccag cttctacaat
    16141 caagaaatat gctacatcac tcatatcatc gcaatctgga taatagataa tatcatccac
    16201 atgctctacc atctcctcaa aagaattgaa gaaagcatgt tgaatctcag aagcaacttc
    16261 accaactggc gttccttcaa gttcctccgc taagccacac aaccgattaa tttcctcaat
    16321 tggcgtatac tcatcaatct caaagggaag ttcataatca tgaattgcat attcctcgta
    16381 ttcgtcattt aacccaattc gttctttcac ttcatcaaaa tcgacaggtg gggtaaacca
    16441 cgcccccacc aattcacctt cgttatattt cccgaggttc gcaatataaa cacgcatctg
    16501 ttccatcgtg cttccccctt acgcaccgac aattcggtta aacaaactga gtaagacatc
    16561 cttcacccca gaagcattaa agaccaatcc gaccgcaatc aaagcaatca ccaaaaagcc
    16621 aatcagtttg gaaaactccc gcttaaatcc taaaaacaaa ccaatgacca caattgccag
    16681 taagactaag gattgggcat tggttaaaaa ccattgatat aaattttgtc cgaaattcat
    16741 cttgtcactt tcctttcttt tccattgctc gatccgctgc tgcacttgca ttcatcaagc
    16801 acatcacagt aacaccaagc atactgccac caaataccaa aaaaatatct tttacaattc
    16861 ccatgacgat tcctcttttc atataatcaa attttcaatt gccatacttt gttgctccaa
    16921 aatcttttta tgtcggtctg ataagcgtgc attctgtacc atatcctgga tataggttgt
    16981 ccgattcaat cgatccaact ccttagccat tttccacgta ggggcgactt gtcggcctag
    17041 ccaattcaag gttcgttcaa tggtatacgg ttttggctcg gaagttaatt gaatctcttt
    17101 ccgattccgt ccaataaaac gcccccattg ttcattcaag ggccagttgg ttcgcctttt
    17161 accttctact ttatccgcaa atcgcaagta acgattgata atggaaaacg tggtgctctc
    17221 aatgctacga ccttttaaca aatcttgaat cgcatgaaaa gcacggtcat ttttcagtcg
    17281 aatctcaaaa cgatttttcg tctcagtttg gtctaatgga atccctaact tgatatattg
    17341 ttcatagtct ttttcataca aacagaaata aacctcactc ttgagactgc cgatatataa
    17401 ggtattgccc atgccgtcct tttcatcagc ctttaaaagt tccccggaac gataactttt
    17461 aaaggtacga aacaaggaga tacattcttc cttctgacat tttttcgtta gctcaggtat
    17521 atccaatagc cccactcgat cattgattgc caagtccaag cgtttcatca cgccaccggc
    17581 ctttagacaa tcctcgaaaa agtcgtacca gctacgcttt tgagcgagta aaaaagtttc
    17641 aaattgtcgg caacctcgcc cctttaattc taaaagcaca cctttatctt cttcatgaga
    17701 caacatcacc acaatatcac ccatgacata ctgttcttga taggagtaaa aggcataatc
    17761 ttcatggagc atatactcaa atttcaaatg gagaatttct tgaataattt ttcgtgcatc
    17821 cgttgtggga aagcgaatcc ttacatagtc aaacagtaac gtcaaaggca aatcgggatt
    17881 aaagctttcc agttggtcaa aaattttcct catggttttt atagatgcgg ttacgccacc
    17941 attttctatc tgatttaagt acggccgact aagtccacaa gccgtagcca atttattttg
    18001 tgaaacgccg tattcgttgc gtcggtcttt taatagccga taatctaaat tccgttgtgc
    18061 caagttctca cctccaaatt caaggtgtta actttttcaa atgagttaac acctatacaa
    18121 attacttact atctttgata caacaagcat tcttaatggt tgcttactta ttttttgtgt
    18181 ttttgtaccc ccctgttaga tacgggggtg agacatcatg gtcggctaac gccgtccatg
    18241 aacaggcaca gcaccacgga ggatttctgc ttcgcgaatc ctccgcggtc agcgcctaac
    18301 agtcagttgt gttggtttag gttactcatc tgtaatacca tttacttcca actctgcttt
    18361 catttctaac aagtattgac gaatatctgg ttcttttgct tggtccgcaa tccgctcaaa
    18421 ttctgcaatt acttgattta tttcaattcg agcatccgtc tcctcattca ttaaatatgg
    18481 atcgccagcg actttgacac cattcttgcg aatatcaaat tttaaccgtc gcaattgttc
    18541 ttctaattct gggtctgact gaatctttcc aatcacccaa taaatttctc caatcaactc
    18601 atcataaacc atgtacatcc aactctttta atcttctggc aatatcaaaa atgaccggaa
    18661 ctgttacaga gtttccggct tgcttataca actgactatc tgaattgact tgagaatctc
    18721 gatcaaaagc ccaatcggga aagccctgaa gtcgccaaca ctctctaggt gttagcttcc
    18781 gaatttgata ctgatccgtg acgatcgctt gttggtctcc tgttagtaag gtatgaacac
    18841 tctgttttcc cagacgacct cggcgacttg tggaattagg aaaagccaga ttcacactgt
    18901 cttctggctt cacctcttga tattctgttt cattttttcg aatcatgatt tttgtaccac
    18961 cttgtttcgt tgacaaggtg ggggcggttc cagtaacttc ataaactcga ttaccttgtt
    19021 caaactttcc cggtaatagt cctgctacag agattccatc ccttgctggc agtgcgattt
    19081 tgattccttc atcacctgtt aaggttggcg ctacgccatc tgaaccatag acttgtccac
    19141 ccattcctcg attggaagga ttgatattta ccaaatttct gatgttttga tcagatgttg
    19201 aagacggtcc aatgatagga aatacttgtt cggtacatgc gtctcgagaa tgtccgataa
    19261 ggaatatccg ctcccggctt tggggaatgt aggcctttga gttaagcacc taccactcca
    19321 cgtcataccc caatccatcc agcgttcgga ggatcgtctc gaacgtagcc cctccttcgt
    19381 gattgagcaa tcctcggacg ttctcaagga ataaaagctt aggtcggaga agagtggtga
    19441 accgagcgat ttcaaagaat aaagtacctc gagtatcgga aaatctttgc cgctttcccg
    19501 caattgaaaa agcttggcac ggaaatccgc cgcaaaggat gtccactggt ccgagggatt
    19561 gaataaactc atctgataca cttgtgatgt catgcatttc cacctcctta cttgtatcat
    19621 gaattgcttt ataactacgt ctagcaaatt tatcaatttc acaaaaaccg atacaatgat
    19681 ggctcgcctg ttccatacct aaacgaaagc caccaatacc ggcgaataaa tctaaaaatc
    19741 tcatacatta cctcattcat tgcaaagaaa aaagccaaga acattttgct cttggctcat
    19801 acattattaa tttgtcctac tattttttat ttaatccaac taatttccgt tgtttttcat
    19861 tggcctgatc ggctacatat ttaatcaccg ttttgaactc ttttgcagta gcattttccg
    19921 ataaatccgc aatgctctta ttgtatttct ttacaatttt cgttacttgt tctttctcag
    19981 tcatgtaatt gaacctccaa atctttccta ctatacccta gtggtaaaaa taattctaga
    20041 ttatccgtag cataatgaac ttcggaaata ttattcgtat aatcttttat tatgatatga
    20101 agcaatacat ctggatgttt actctttact tttgcaatgt tctctcttga tttgaaaaaa
    20161 gcgttaataa atgccttttt cggcacatga cgtccctctg caatttcacg ttcttgtgta
    20221 aatttccaag cgattttagg gtcttgataa acatagaaaa tcgtcactcg aaaatgtttt
    20281 ttcaacgccc gcgagatatt tttttcagca cttaatattg caaaagttgc atccagaata
    20341 aaagaatagc catgatctaa gacatatcta aatgcctgct ctaccaacca agaagatgct
    20401 ttttgaaaga gactagagtt ttttccatta taatcaggaa actgggtgcg aaagtaatcc
    20461 gcatcaataa tcacatggtt atcataattc tcagctaatc caatggcaac ctctgatttt
    20521 ccagccccag gactccctgc cataaaaact gcgtctcgtc caacttcggg ggatttccct
    20581 ttgataatat aagaaataaa cttatcctta tttgcttttg catactctaa ataagaatca
    20641 ttactttcca tattaattat cccctttctt cctactatat aaaagtatta tacgttactt
    20701 gaagtataaa gtcagtattg aagatcactc aatcattcat cttttctaat ttactaattg
    20761 aatctaagaa atcataccct tttggtacaa gtggcgtata aaactcacta atcacactgc
    20821 cacctgtatc cacataacct cgacctttga tgtgcttcat aaagaagttt ttttcgacct
    20881 ccccaaacat catggaatat ccgagttcac tcatacgacc caaagccacg cgaaagttga
    20941 attgatcgcg gattccgtct cctaaatatt tcgcatccgg cctttggcaa gccaaaatca
    21001 gaaagaaacc agattgacga cccaacatca cgatttgttt gagcttattc aaaatcaccg
    21061 cactttcttt cgtcgttaac atctccatat aagccacgta ttcatcaaag attaaaaagt
    21121 tgggtggaag tccaagatag gcataattct ctcctgtttt gtagttagac atttctttca
    21181 ttgccttgct acgagccatc atacgttcat agaaatcttc cacacaagca gaaatttctt
    21241 ccttttgtga ataaacatga ggcatcaccg tacctaaatc agctaaatct gcatttttgg
    21301 gatcgaggat aaacaattct gcatctgact tcaatagtgc ttcgataatg gtgaggagga
    21361 aataggtctt ccctccaccc gtgccaccag cgattaacat atggggtaaa gaatcataag
    21421 cccatacttg atttttcatc aatcgcagag tcccattttc tgccactact tcgtctatcc
    21481 caattcgatt ggcgatcata tcatacagta aagtatactc cacataggag tctttgagtt
    21541 ccttttctac taactcacaa tacagtccgc tttctaactt cttttccaat tttaaaagct
    21601 gatcttggta tttcccaagt gaaatttgaa cgcgaataga cagtaatcca tctttcattc
    21661 gataatagat tttggggaag taactgatag tctctctggt tcggctacta ttcaaatctt
    21721 tgaaaaagcc ttcactttga gtttgtttca cttcatacca atggttctct agaatcatcc
    21781 gagctagctt ttgtcgatgc cacaagcttc gccaatgatc aagaaaaaag tgaatataaa
    21841 gcaatatcat agctcctgaa aaagcgagac ttccaagcag acatactaaa tcttttatag
    21901 accaaacgat ttcaatagta gaaagtgata gcttagaaat atcaaattgt ctaaactctt
    21961 gaaaataaaa gacgctcatc caaccgatga acagagcgag tagccagcca agaacaaagt
    22021 gataaaccaa gtgctgatct cctgcgcgta tgcgatgtcc tttgtacatt ttgatggttt
    22081 ccacctccaa tcgaaaaagc ccaataggat ttcattaggc aatttcaaaa agttatgcta
    22141 gtcatttact gctacgagga ggggagttgt ttcgtttcaa ccaattgatt taaaaagcct
    22201 tcaatagcat ccggcatctc cacaccaatt tcttccaaaa tggattctgc ctgccgacat
    22261 aagttttcat ttacttcgac aactataaag aaagactctt cttctcctaa ccagtctagt
    22321 acatcagagt cttcttcact gtcgctattt tctccaagta aaccttgatg tataatcaga
    22381 aacatttttt catcagaggt taatgcttta acgagttgtt cctcagtcag ctcgcctttt
    22441 ccatattgat cgagacaatc taaaatatgt tcaacattaa tttccataat cttcacctat
    22501 ttctttcttt cattttggtt cgtaggattt ccttgattcg gctgccgctt caagactaaa
    22561 tcatccgcct taatgaacca attaacggta gttccttctc gaaaaacata attggcaacg
    22621 gtatccacga ttggattgac caactctacc tctgcatcat aagcaaactc gcgtaagggt
    22681 acattagctg ggatactaac ttgaatcatt cgcccttgtg cagaggattt taaattatag
    22741 gttcgttctt ttacctcatt accaattgtt ccatcctcat tttgcttccg tacttctcgg
    22801 cgtaatgcgg aaaaacgcaa cttcccaaat gttaaacctg aatctacgac aataccttct
    22861 gttaatctca tcttcttttc ctcctatgct ttcactaaat catcaacata caacacgtaa
    22921 tcagtaaacc cacgattctc aatctcatag cctttggcaa ccaaatgggg attcacggct
    22981 tttagcggtt ggtcttgatc aaaatccttt tcaccggctt ccgcagctac taccacctca
    23041 atatcatcgg cccgttgctt actggaatac aaatgataac tgcgaccaat caccgtagta
    23101 ttccgtccat atccttctgt tataatttct ccttcaccgg cataacttaa ctttccaaag
    23161 gtttcagcca tatctggcac gacaaatttc aattccatct tcttttcctc ttttcattgt
    23221 tagttttgga tacaaaaata gcgcgactac ttttttagga ggcggtcgcg cacgttggtt
    23281 cttaggattt acttgtatca tctcatcacc ttagttccgg cgattccaga aataatagcc
    23341 cgccgtcgca aaaatcaaag taaaaccaat gaacagtaaa acattggaat ttttctcccc
    23401 ggtttgaggg aaggtcttca ctgtgggact agattcttga gagccacttg gaacagttgg
    23461 tgtttccggt tgtttcggcg tacttagtat ggttggaact tcttttggtg ttaaggtttg
    23521 agatttttct ttcaaatctt cattgtgttt tccattgata ttcccatctt tatcgtaatt
    23581 gatttccgca aaagtaaact tggttccttc tggatatttt ccggtatcta cttttttcgc
    23641 aagcacagtt ttggtgaatt ctttatcatt tacttcataa tcaatcttgc cagatttcca
    23701 aatttctttg tttgtaccat ccggtaataa agcatacaga attgtttcga aagcttcttt
    23761 tgagccatcc agtacatcat gagtaatcga cacatcatca aacatatcca ccacatcacc
    23821 atgagtaaag gtctgagaac cgttttctag gtgggccttt gtttggatag aaacatggtg
    23881 ttccactgta caactgacag tttgggcttg gttattcaag ctaacatcct tcgctactgg
    23941 cttatcgcct gcttcaaaag cttccttatt ttcatacaca tagttgaata agacaatagt
    24001 tttatttaaa acttgttcgg cggttaattt atgctgaatt ttccaagttc ctgttttctc
    24061 tttgttcgcc aacgttgcgc ttgtttctgc aatcaccact ggtttggctt tttcatcttt
    24121 ttcttgggca gcttttgtcg catccacatc aatggcttgc gctaccacat accagtcttc
    24181 tttgatttca tgtagattgt aactcaattt atcaactagc tcggtagaat ccagagaagt
    24241 taattctttg tttccgtctt tccaagtcgc aagagaagtt aaactatctt cttcctcagg
    24301 caaatcatag agcattaaac ggttcaaact aacagaaaat gctttgttcg tcagcttctc
    24361 gtaaggaacg gtcaccgttt taattggttg tttttggtct tgttcggtaa tggtaaagac
    24421 atactcactc ttcacaaagt cttctttgtt ttccttaaaa gtagaacgga tttctaatgg
    24481 cgtaatcttt tgaaaacctt ctggggcttc tacttcttca agtaaataat ccccataagg
    24541 aagattttca aacttgccat aaccatcaaa ccctaattgc tcgttataag ctgtggtcgc
    24601 ttcatcttcg gcacctgtga tttcattggt cccttccaat ggcgacactt taaaggtcag
    24661 atcattgaag ccagtttcgg tagtgcccgc agctgatcca gcaaatttaa agaaatcaaa
    24721 gccaaagcga atcacttgtt cttttgccgt aacatttcgg gtaatcacgg catttttttc
    24781 gctatcatcc acctttttga tggatacagg atactttgtt tcatcaaggc tatatccttc
    24841 gggcgctttt gtttcttgcc aataatactc gttgatagct aaatgtttaa cggcaacttg
    24901 gttcttttcg tctaaagtca aagtgaccgt ttcatcagaa cctttcgttc ccttcgctaa
    24961 ctctggttta aaagcctcac tccatttaac agcttttcca tccttagcag taaacaaggt
    25021 gtattcagca ccctcaaaga ctgccttacc ttgtgcttta tccccagtat ctttgtcttc
    25081 tttcgtcaaa gtggtttcgc cagtgacttc ttgattttgc ccttttacgt tactggtaac
    25141 aagggctacg gtttgattgg catacttcaa ttcgactttt acaggtttga acgtattcac
    25201 gaacccatga ctagctttag tttcggtcac ataataggtt cccaattcca acgcattagc
    25261 aatctctttt ggtgtttccg catgaccgtt ttcatccgtg gtcatttctt gaacgatttc
    25321 accggttgga ctgtctttgc gaatggcaaa cgtattacca gctaaggaat aattgtcatt
    25381 ccaaagatca ctccctgttt caactccgct tttatccaga atgatttgcc ctttttcccg
    25441 tgcgtttttt gaagtcacgt aaatggtttc gcctgcttta atggtggtag tcatgggggt
    25501 ggtatcaatc gtataaggcg ccggtactga tttttcggta atggttactt ttgtaccatg
    25561 aggaatctca tccaatgtag caatgccttc tttgtcagta gtcacgtctt ttgcaggtaa
    25621 agtttttcca aagtctaaat ggaaaaccgt tcctggtaca acatcacccg attctttatc
    25681 gacttttttg atctttaaag aaccctccgt ttccacatca attttgattg tgtaggtatt
    25741 aggtttatca atcgccccgg ccattaaagt ctgttggcca gcctttttat aggcgacagg
    25801 tgttccggta ccagcagatt tcttaagcgt cagcacacca ctttcttttg aattggcatt
    25861 tggggtgatt atcaactgat taccattcac acgataatca atgtttgcgg cattttccac
    25921 aacctcatcg aactctgaca aattcagatt attcgtatcc gtcacagtag tcgattgccc
    25981 taatactgtt ttagccgtac tattatggaa ggttggtttc ttctgataat cgtcaatggc
    26041 ttgatttatt tttgcctcaa tggctgcgat atttacggca ctaccatctg atcgttttat
    26101 tgagtgaagg gtatacccat taacttcttg ccagatcatc ttctgtgcca caatatgagt
    26161 atctgcatct gtacctactt ttttccataa aacggaaact aatttggctt tatcggacat
    26221 atctggtaac gggtttttct catagccagg agtgaactca ttgtaaatcg ggactcctgg
    26281 ttcaatacag aaaatatctt gtttaaagcc gttgtacact gcataatgcg gaacagtgac
    26341 ttctgacatt ggacgaccat cactaaaagt tccttcaaca gcatattgat gtgctaaatc
    26401 tagttctacg gttaccgttt gtggatgggt aatttcatca gcaaaagtaa tcgtaggagc
    26461 aattgctcca acaattgctt gaacagccaa actcaaaata gttaatacac ataatttctt
    26521 tttttgtttt ttatacatga aatgttctcc tttcaaatta agcacaaaaa aataagatgc
    26581 tcgcttgaac atctttgttt ataaagtctt tttaaaattt ttattgactg aatagaatgg
    26641 atttgagaat gaatgagcct aaaaatttaa tctaaaatac gaaatatact gcctttaaat
    26701 tagaacacat tttagaacac aaacatttca aatttaatca aatataataa aatatattta
    26761 cgggaaaacc tttataaatc aaggtttttc aaacttattc aatgatacga agaaaaaacc
    26821 aggtcttaag aaagcacgta aagcttcaca gttttcaaaa cgttaatcgt tgttatacca
    26881 acgatttcag acactttctc attgcgagaa ggtgtctttt tttcgttctg gtaatgagaa
    26941 aggtaatgac aatattataa accagtgtaa gcaatgaatt tttctaacgc atttcgttga
    27001 gctttttcag taacatgaga ataagtgtta agggtagttt cagcattttt atgacccaat
    27061 cgatcttgtg tttctttgat acttgctcca ccttctagta gaagagtagc gtgagtgtgc
    27121 cggaatccat gaatagtaac gtgcttaaat ttatatttct tctctaaacg tttcaatata
    27181 ttatttgaat agtccgcatg caaaggttga ttaatgtcac cgtctgcatt tacataggta
    27241 aagataagtt gattttttgt atttgtattt atgccaaact gcaaaagctc tcgagcttgt
    27301 tcttttttcc agatttttaa catttcaata gtttgtgcat caattggtaa tattcgttcg
    27361 gaagatatat tttttgtatt tttttgaatc ctgacagttt ttcttcttgc attcttctct
    27421 tcatttcgaa tagttgcata gctctttcta acatacatta gctgttcttc aaaataaatg
    27481 tcagaccaat gaagagcagc tagctctcct ttacgtatac cagtagtaat caaaagctgg
    27541 aagattaaaa tatgttttaa aggctcttct ttattgagaa tatcccaaaa agcttttagt
    27601 tcttctaatg aaaagtaatt ttcattttct ttcttttccc gctttggtag atttgtattt
    27661 gccataggat ttcggtgtaa tagctctgca aaaatggcat actcaaatat ttgagagctg
    27721 taagacttaa gctgtttgat attcttgaat tttaaagccc attcattgac tgcattctga
    27781 cagtgaacag gagtaatctt agaaatggac ttattcccga attttggtag tatatgcaag
    27841 cggaaaaggt cttttgtacg ttgatatgtc gtttcttgta cacgattcct ataagaaggc
    27901 aaccattctt catacactgt tataaacaag tcattagaag gcttatgata gccggtatct
    27961 tcaatctcga ccttttttct tgcttcgtgt aacttggctt ctttttcagt tttaaaccct
    28021 ttttttacat agtattcttg ctttccattt tcatctttac gaacatacaa gcggacacta
    28081 ta
//
LOCUS       DAIGTA010000037        27951 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.037, whole genome shotgun sequence.
ACCESSION   DAIGTA010000037 DAIGTA010000000
VERSION     DAIGTA010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.037"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..280)
                     /locus_tag="NOB43_001697"
     CDS             complement(<1..280)
                     /locus_tag="NOB43_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HCI0982553.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELT"
     gene            complement(369..1400)
                     /locus_tag="NOB43_001698"
     CDS             complement(369..1400)
                     /locus_tag="NOB43_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0982554.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            1607..2482
                     /locus_tag="NOB43_001699"
     CDS             1607..2482
                     /locus_tag="NOB43_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0982555.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(2634..3476)
                     /locus_tag="NOB43_001700"
     CDS             complement(2634..3476)
                     /locus_tag="NOB43_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0982556.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(3568..5445)
                     /locus_tag="NOB43_001701"
     CDS             complement(3568..5445)
                     /locus_tag="NOB43_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0982557.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVCNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(5442..6863)
                     /locus_tag="NOB43_001702"
     CDS             complement(5442..6863)
                     /locus_tag="NOB43_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0982558.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(6866..10255)
                     /locus_tag="NOB43_001703"
     CDS             complement(6866..10255)
                     /locus_tag="NOB43_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI0982559.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            10512..11903
                     /locus_tag="NOB43_001704"
     CDS             10512..11903
                     /locus_tag="NOB43_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982560.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(11976..12623)
                     /locus_tag="NOB43_001705"
     CDS             complement(11976..12623)
                     /locus_tag="NOB43_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI0982561.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(12631..13317)
                     /locus_tag="NOB43_001706"
     CDS             complement(12631..13317)
                     /locus_tag="NOB43_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982562.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(13323..14396)
                     /locus_tag="NOB43_001707"
     CDS             complement(13323..14396)
                     /locus_tag="NOB43_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982563.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            14618..15292
                     /locus_tag="NOB43_001708"
     CDS             14618..15292
                     /locus_tag="NOB43_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0982564.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            15297..16637
                     /locus_tag="NOB43_001709"
     CDS             15297..16637
                     /locus_tag="NOB43_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0982565.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(16786..17772)
                     /locus_tag="NOB43_001710"
     CDS             complement(16786..17772)
                     /locus_tag="NOB43_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HCI0982566.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            18496..19527
                     /locus_tag="NOB43_001711"
     CDS             18496..19527
                     /locus_tag="NOB43_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0982567.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            19636..21168
                     /locus_tag="NOB43_001712"
     CDS             19636..21168
                     /locus_tag="NOB43_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCI0982568.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            21307..22119
                     /locus_tag="NOB43_001713"
     CDS             21307..22119
                     /locus_tag="NOB43_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HCI0982569.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            22109..22594
                     /locus_tag="NOB43_001714"
     CDS             22109..22594
                     /locus_tag="NOB43_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0982570.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            22617..23162
                     /locus_tag="NOB43_001715"
     CDS             22617..23162
                     /locus_tag="NOB43_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HCI0982571.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(23235..24878)
                     /locus_tag="NOB43_001716"
     CDS             complement(23235..24878)
                     /locus_tag="NOB43_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI0982572.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(25007..27235)
                     /locus_tag="NOB43_001717"
     CDS             complement(25007..27235)
                     /locus_tag="NOB43_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0982573.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(27268..27747)
                     /locus_tag="NOB43_001718"
     CDS             complement(27268..27747)
                     /locus_tag="NOB43_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982574.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT         8010 a         5289 c         5098 g         9554 t
ORIGIN      
        1 aggtcagttc ttcaaatttt tctttgacat cttcaaccgc tttttcgata tctttttcaa
       61 agtgattggg ctcattaggc tttgtttcct cttctacaga atttgaacca gataaagctg
      121 tttctttatt ttctgtttca ccagagtttg tgccagctaa tgattcttct ttgtcttctg
      181 tttcaccaga attagttcct gctaaagcca cttcttcttc tgttttaggg gccattgaac
      241 ctcttaatcg tttgtgtttt tcaccgtcat aatttgtcat gttggttcct cctagtagtt
      301 ctatactttt tcatcgtaca ataagacagt ttatgcgtca aaaaacaaac ccgattctta
      361 caaatatgtc atatttttcc ttctgattct tgaatgcttt tgattccttc ttccaaaatt
      421 ttcatttgta agattgtttc ttcatctttg atgacttttt ctgcgccatt aactaatgtc
      481 tcgtaaatcc cttcgtagac acggctgtaa tcaccaacct cggaaattac tttttcttca
      541 tgataactcc cttgttcatc tatataggtc aatacaccat aatgttcggg caaatcgata
      601 ccaaagtctt catgatcagg catgtaaaac attttcagat gttcttcttg tcgatctttt
      661 gtttgtttca cgaacatccc tttttttccg taaacgacga aacttggacg ttctttgatg
      721 cggaaataac tggattttat cgaaattttc atatttccat agaaaaaatc cagatcgaag
      781 taatcattca ttcgtccttt ccctaaaagt tgacgtacat catagctgat atcatctggt
      841 tcgccgaaat aagaaagaac ttgatctact gtatgacaag catgtccata taaatagctg
      901 ttcgcagtag aaaattcatg cgtattttct ggtacttccg gtctgaaata atcataatgc
      961 atttctactt ctaaaatatc ccctaatttt ccgctttcga ttactttttg gactgtcaag
     1021 aagtcagaat cgaaccgtct gttttggtaa cattggataa atagaccttt ttcttttgct
     1081 aatgcaaata actcttctgc ttcctttgac gtttctgcaa aaggtttctc tactagtaca
     1141 ttcttaccat gttcgagtgc catttttcca tattcataat gaaattgact aggtgtagtg
     1201 atgacaacta attggatctc aggatcatcc caaagatcag acagctgatc agtatattcg
     1261 atgtcttcga atgttttcca cactggttca gatggggaaa aaattttttt gatattgatt
     1321 ttgttcgtaa gttttcttga aaaaggcaaa tgatagcgat ttgtactctt tccattgcca
     1381 agataagcga ttgtaagcat gagtggtgcc tccttttatt gatgttttca gtatatccta
     1441 gaaaagcgca gaaagtattt ataatagcta ttctggtaaa aaagttcaga aaaacacttg
     1501 ttatcattcg gtttggtgaa attaatgttc aaagtaagga taaaaatcaa aaagatagta
     1561 gcggaaccaa gtgtttatca gtaagataga atttggaggt cagatcatgc ttattgaaga
     1621 aaaactaaca aaacaagagt tgtttaccac gacagagaaa cggattgtcg attacatccg
     1681 taggaatatc gaagctgcag tctacatgac gattgaagaa ttagcaaaag ctacgtatac
     1741 ttcccattca gctatcattc gtttatgcaa aaaaatggga ttcagcggat ttaaagaatt
     1801 ccgtttcgag ctggggcggg aagttcatca attgattgct cagttcaatc aaacgattga
     1861 tcctaatttt cctttttcaa gtgaagatag cactcagcaa attgcaaaga aaatggcgga
     1921 tttatcgatc cagtcaataa aaaaagcaca attgcagatt gaacatgaag atttagatca
     1981 aatcggtaaa gtattgaaca aggcacagcg aatctttctt tttgcaaaag gtgattctca
     2041 aatcacggca aggaaattcc agaataaaat ggtcaagttg aataagtttt tgatcatggc
     2101 tgaagaatac agtgattctt cttggaatgc agccaatttg actagcgagg attgcgccat
     2161 ttttattagc tacagcggtc gcatccatca ttatgaacga ataatgacct atttgaagca
     2221 tgtagaggcc cctaccttgc tgattaccgg aaatcagcat tcagaaatgg ccaaacaggc
     2281 tgatatgtgt cttgttatat cgcaggagga atatgatttt gctaaagtag cgactttctc
     2341 ctctcaaatt gccttcgatt acgtattaaa tacgttattc tcagtgatat attctcaaaa
     2401 ttttgaagag aatatccgca acttgaaaaa caaacaagaa ttgatgcaaa aaggccttct
     2461 taaagaatat cggaaaactt aagaaaagat cctcatttag taataagaaa gatagtgttt
     2521 gataggctct ctttgatatc atcataaaaa caggctgaag ttttcttttt caaacctcag
     2581 cctgtttgtt tacggaacga ttcgaataga tatattatag aaatgaggaa tagctaactt
     2641 ctgtttctta ttttgaacga ttgacgaaaa agatatataa gaaggaggaa aatcagtata
     2701 catgcagcta acaatccata caggaaaaat cgtttgttct cggatacttt ctgtacttct
     2761 ttttgaactt cttttgcatg ataaggaacc cggtgccctc tgacaagtaa gcgatgactg
     2821 ttgaccatat aaggtgtaca agttaggagt gtcacgaaat cctgcccttt ttcgattctc
     2881 agatcttttg tatcagtcgg ttctaccgtc ttgatctgat cgacttgata agcgagtgtc
     2941 cgtccattga tttcgatata gaaagaatca cctaaagtca gtttcggtaa gtctgtgaac
     3001 aactttgctt gaggcagtcc tcgatggctg gaaataacgg catgtgtatt ttctcccccc
     3061 gtaggataag acgttccttc caataatgag gcaccttttt ctagcagcac agtattcgtt
     3121 tcatcaaaaa ttggcaaatg gacattgatc tcagggatcg tcaaaatacc gatcgtatgt
     3181 ttctcaaaat aggttctatc ctttttcgca ggttcttttt tcttagtaaa gggatctgca
     3241 cctggatttc caccttcttt tgctaattgc tggtttttct ttgtcatgtt ttcttggatt
     3301 ttagccatga cttcttcatt ttctttgacc gcttgttgct gataatgaga gatgatctgc
     3361 tgatccagat aattattcag cgcgtcgcta acaaatggat aagctagtat ccctattcct
     3421 gagagaagca agaaaagcat cagcagatct agaagtttcc ttttctttgg tttcatttgt
     3481 gttctccttg tgatgactgt ttgataataa aagaaaaagg agcatttgcg taatccgctg
     3541 ctcctttttc caattcttgc aaaaagacta aatctgactg tgcttgcgtc tagcaaagta
     3601 cagtccagca atcagtagaa ggactactcc tgcaccgata tacacataga ttcccttacc
     3661 gcctgttgaa ggaagtgtac ctttgtgttt atttggtatt ttttcaggag aaatcaactg
     3721 tcctgctgtt acataagatt gttcatcgat agtaaatgct acacggtttg ttaatggaac
     3781 atatttttct ggcgctttcg tttcttccag atagtacgtg ccatatttta gacctgtcac
     3841 atcgattaaa ccgttacttg tggttgtaaa aaccgttgct gattctttcg ccgataccca
     3901 gctgacggct tttgtggatg ggtcgatcga taaatatttc gctgtgtcac tatcttgatc
     3961 acgaacgacg aattctgctc cagcaagtgt ttggtctgat gtaacgtcac catctacttt
     4021 aacaaatcgt ttgcccccag taacgacatc gactgacggt ggtgtttgat catttgtatg
     4081 cccgttatcg acatttgctt ggttagaaaa tcctttggtt ggatctgctt tttcgttcaa
     4141 atgcatatag taaacgaatt tcaatgtacc gccaggagtt aatgaaggaa tataattcgg
     4201 atcaactgaa accgtgaatc cgtctgtttg ctcagtgaca gaataattta ctgggtcgat
     4261 ttctttattt ccatcatata aggcataagc atacgttcct gaagaatcat tatcaaatgt
     4321 taaagcagcg tcatgagtat cgataagttt gaatgttgtg tacttgtttt gcgttccttc
     4381 tttatcagcg atacctaatg ggatattgac agaaatctca tattgaattt tttcaccgat
     4441 tgcgacatct tttccattca attgaggtgt tgttttatca actttagacg tatcattttt
     4501 gatggtcttt tctactggtg tttggctatt tgccaggatc tcaaaaggcg tgattgtttg
     4561 cttttcaatc atttccgcat tatcaggagc ttttacttct tctaaattat attttccaac
     4621 ttctaaatga ttaacgatca actggccttt ttcaatagat gcctcggcaa agtcattgtt
     4681 gccgatgtca taagaatgac cagtaatgaa atgtttggct ttggtttgat cagttgtcca
     4741 agtgtacaat ccatctgtga cactttggat gtattttttg acgcttggtg ttccttcttc
     4801 tttagaaata ataaattctg ctccatttag tgcttcgttt tcggcagtac cgatttttgt
     4861 aactttcaac gttccatcat tacagactgt atttttaggg tagagatgga tagtatctag
     4921 ttcttctgtc ccgtatttat aagagccatc tgcttgtttg atcatctcat atacagggaa
     4981 agctaaaacc atgtttgcgg cagctgacac tccgtctttt ggttcttctt tgatcgtgta
     5041 gactgcatct ttcccatttt gttttttagg taaagataaa gtgacatttc catcagcatc
     5101 tgtcgttcct gaagcaactg gtgtaccagg agtcaaagac tggactgctt gttttgctgc
     5161 atccacggac gctcctttat ctcgttgcgc ataaaattct tgagtgacgt tataaactga
     5221 aaatgaaata tcggctaatc cttggtattg atcgaattcg ctcatttctt tcccgctgtt
     5281 ttggattaaa ggatcgggta aatcagtcat tttcttttta tgaaggatga cttgagctgc
     5341 tgtctcctct gcaaacactt tttttgcgcc gaagctgttt gtgagtaatg gtaaaataag
     5401 gaaaaggact cctaacataa cgtttatttt tttatgattt ttcatttttt cactcctgtt
     5461 ctttttttga taaacaacca gattgcaaag cttgcgaata ccataccaac aacgcctaaa
     5521 agtgtatttt tcgtttcgtt tgtttttgga agaaatggac ggctattttc ttttttattg
     5581 actactttca atatactgtc cgcctcttta tcctcagaaa gaaaagttga aatggtaaac
     5641 ggaatttctg tttcacttaa aatataacca gaaggtgctt cgatctcttt taatcgataa
     5701 cttcctgttt tcaacccgga aattgaaaaa gcgccatttt tatcggaaat caggtgaagc
     5761 gcatctgatt cgttctttgt ccacttgtat ccgttggctg tttgctggag gtaatttcct
     5821 gctttgtttt taataaggaa tactgcgcca gctaatcgtt tatctggttt atttgtctcg
     5881 attttgacaa attgcttact ccctgtatat acagagactt tctttgtact gacaccaaaa
     5941 ccaaaatcca gtgttccgtt gttgttgatt tccttgttcg cctgtgctgt actgcttagc
     6001 tgcatctgat aagaaatggt cagttttttt ccagcatatt tttccaacga agggatcgaa
     6061 aataaaacat caaatccgtg aggtttcttg tgtatgacaa agccttctgt cagcttttct
     6121 ccattcgatg aaatcgttaa actattaggt aaaaacgtta atgcttcatc cgcactatct
     6181 gacaattcga acttttgata gtcaaggata tttacaggaa ttgtcgtatg caaggaataa
     6241 gtgatttttt caccaatcgt aaaatcattt ctaggctctt ctaatacctt ctcaaaaggt
     6301 ggatcagggt agtcgttttc ttcattttta ggatacaaat ggatagttga aagtttttga
     6361 ttgttttgtc catgtacagg aagaacaact accatattct ctgccttttc tttgacgact
     6421 tctggtactt tggattcaat gaaaagatac gctttatctc ttttttcttg atctttagcg
     6481 gccagagaaa aagaagcgat accatcttcg ttgttaagag ttgtagttgt tgcttctgcg
     6541 gtaaacatac cggaagacgc accgtttttt gcgatctctg cttgtgcttc ttctaccgtt
     6601 ttgccctttt cccgtagatg gtaaaaagaa tctgtgacat cataaacttg gaatgtgaca
     6661 ccatttaatc ctcgatacgt ttgtaataaa gctttttctt gtccgtcatt tggatgattt
     6721 ttcggcagtt gcccgtttgg gaaaagcaat ttgtgtaaag taatctgaac catttctgtt
     6781 tctgtttctg ttgctacctg agtaaaagct ggtttaaata gtaacaagaa gagacacata
     6841 ctaagccaac caagtttttt catatttagc tgccccctct ttcttttttc aaaaaaagat
     6901 accaaataga aaacgcacaa ccaatcatcc ctactagata gattcctaaa cggccaattc
     6961 ctcccgtttc aggtaatggt acttttgcct gattcgtgat gtctaaagaa atctggttgt
     7021 ttttggctcc tggtgacaga acagattcat gatcttgtcc atccacttga attgacccat
     7081 cttcgtgtat aactatagta actggctctt ttagaccttg gtatccttct ggtgtaaaag
     7141 tttcggtcag cgtataagtt ccaggtttta aattttcgaa tagaaaggta tctgtttctt
     7201 gtccatcttt tggcgattct aagtccattt ctggtccctg cagtctgaat tttgctcctt
     7261 ttaatgtctg tccgttgtct tcttttttgt gtaccgttag atcaaacgct tttagtcgat
     7321 tttgatgagt gagcgtccat acattatttg tcatctcggt attttttccc gtgtaaatga
     7381 tttttccata tttatcgatt tggaattcat aatttcccgg cgaagtatca tatccggcag
     7441 gaccagctgt ttcaacgact cgatatttac caggtgtgag tgaatcaaaa ctggcaagac
     7501 ctttttcatt cgttgtttgg ctgtcaattg gctgataagt accatttgct tcttttttct
     7561 gtagggaaaa tgctgctcct ttaagattta tctctttgtc cgtcccttgc atcgcatact
     7621 tacgtactgc tacaggaact tcaacaaaag gattttcaat agtcaactgg atcgtatcat
     7681 cggaagtagt gactgttttt ccatcaatgg ttaccgtacc atcagaagcg atcttgattt
     7741 cccaagtagt ctttttgctt aatccatgcc cttctggagc ttttgtttct gtcagcgtat
     7801 aggtcatttc tttttgcaat ttgacatttt ctggaagaga ataggttccg tcgccatgat
     7861 ctgttagtaa agtatcaata gaatctcctg ttaatttgaa aacagcgcca ataagatcct
     7921 tttcacctgt agaggaattt ttcgttattt tcaagtttaa cggtgtgaat tgtttagtat
     7981 ttttccatgt cattgcatct atttgttgag aatcgtatcc tggtacaggt aattctttga
     8041 ttgtttggta actgaatgct tgaccttgat tattgtattg aggtagtgat aatatctctt
     8101 gataactttc tccgctattt gcagataatt tgtcaatgtc tgcacgttcc cacgtatttg
     8161 ttgtatcttt agctggttta atgattcgaa tatatccgtt tttccaagct gcagcatttg
     8221 tcgtatgttc ccgttgaatc tcaaaagtaa cttgatctgg acgatcagct agattgttgt
     8281 caaattcttc ccataacttt ttgatgtgaa gactgactcc gggagcttta gcagatggta
     8341 taccgaattc agctaattca ttggtatcaa tgtttggctg gaaagttgtc ctgccgttca
     8401 tttgatacca gaaatttgga tggaagtcct cattttctgt ttggattctc acttggtaat
     8461 ggatttggat ttcttggtct tttcctaaat agatctgatt gctcttgatg gtatttcctt
     8521 ctatggaaat agatggagtg accgttgtag gacttgtccc cacactcttg actgaaagtg
     8581 taccaggctg ataaatgaat ggttctgcga ttggatcatt tatttgtcca ttgcttacag
     8641 ttgctgagat ctgtacagct tttttggcta ggtattcaga gatatctgtt gcatgatcag
     8701 ctgattcata gtaaagatcg cctttttcat ctgatgaaac catttgtcgc atacgagact
     8761 ctacttctgc ttttgagaga ccagctgccg gatcgctttg aagttggatg ccaagaccat
     8821 gtatttcgat tcctcgttct ttgagtgcca tcgcttctcc gatggttgcg ataaacgtac
     8881 tgtcgattct tctggataga ttgttttggt caggtgcatc atagattctt gagattagag
     8941 aagtatttcc cggccgatct tgcgtattag aaaactgagt tccgtaataa ttgctgcttg
     9001 attgtgcgtg tacccgctgt actttatagg aaaatgttgg tacaccatcc gtcagcaaaa
     9061 cgatcacttt tttatgtcca tttggaacgg atagcatgct tcctgcatct cttagtgctt
     9121 tttgtgtaaa agtaccacca tttgtccgtg aaggtgtaat ggattttact tgatttttca
     9181 ctgaatcaaa tgaacccatc tgtactgcac cgttactgta gctatatcct tcgcttgagt
     9241 agccgacata tcccatattg attttgtctg tgataccgct atctgctaaa gtatcgacaa
     9301 aacgatcgac accaatcttt acttcaccga tccgattatt gtcgttcata cttcctgacc
     9361 agtctacgac caatacgaga tcaagaggcg tgatatcttt ttgtacattt ccacgagcat
     9421 tcaaataaac atcaaacaat ccgggtgtac ttgtttcctt tgcatacttt cgtatcgcat
     9481 agtctgcttg attaccggtt cctccatatt cgatatacga atgggtccga tcattaggat
     9541 ctccattcca agaatttata ccatcccatt gatttgttcc gtttttattg ccttgatgat
     9601 caagaacatt tgtatttcct gtaggttgcc aactggcttt aggataagtg ccctgatcat
     9661 ctgttgtata ttctgtagga atcgtttgat tagatggcac actcacagct ggcaaggata
     9721 atgtaggcaa tgtaaatggg ctgacagaat tttcgttttc ttttgatgat tcttcttcta
     9781 tttcgtctgg ctttggtact gacacatctg tatctttctt attttctgtc tcatcaataa
     9841 tgtcatattc tttattatcg acgatcagct tgtttgcctg gctgtggtaa agtgctggat
     9901 cgattggaaa actcagatcg atagtttgtt tagtgtttga tgagatttcc aacgtaattt
     9961 tcccgctatt tacctgataa gcatagccat ctccttcttt tctttccaca tcacttaagt
    10021 aattttcgac tagaccaatt tctttttcta tcttttcagc actggtgtta ttcgcattta
    10081 gcttgatgtt cagtgctttt tttccagact gatccgaaat gacttcagct gaaattgttt
    10141 ctaaaactgt tggatcatct gtagtgtctg ctattgcaga taatggcaca aagtttgata
    10201 aactcaatat tatcagcatg aaaataactt tcagtttctt ccctgtggtc gtcatttttc
    10261 ccctcctttt tctttttttc tgttttgacg tgaatagtga aaattattaa aataaacagg
    10321 cgttacataa ttttatttat tttaatatga taattattat acgaagggcg ctaaagggaa
    10381 tcacaccaat tttcatacca attggtttca tttatgaagt tgattccttc gattaatgag
    10441 cgtttcattg aaagaaaagg gttgagggag aaaaacatat gatcaggttg ttggaatgaa
    10501 actatagaaa gatggaaaaa atcattcgaa ttctgtccat ttctgacaag tggatgacta
    10561 aaaaagaact tgccaaacga attggtagtt cagaatctac atttgtaagg tatatcgaag
    10621 agatcaaaat ccgctgggga acggatgtaa cgattcaatc ttcacaaaaa ttggggtatc
    10681 gtcttgaaca tttgaatgta ccagcttatt taaatgttct gatggaaatg tcgcaaagtt
    10741 ctacaaacag tcgtttatta aatgagatta ttgtcaatcc gggtaaaacg attgagtatt
    10801 attgtgaaaa aatttccatc agccggtctt cttttacacg taagttgaaa caatgcaatc
    10861 aaattttaga aagctattta ttaaaagtga tcgttgacca aggttttcag ttaactagcc
    10921 ttaaaagtga gctccagttg cgtatctttg ttaccttttt ctttttaagt tactacggaa
    10981 gacgcacgtt gccatttcca atcgaaaaaa agaagatcaa agaaattatg gtcaagaata
    11041 attgtcagat gaatttgttt caggaagaaa gcccatatga gcaatctttc tttattatgt
    11101 attttgttgt gcatctcatg agagaatccc aaggaactcc atttgaatgg aaagctggag
    11161 actcttatgt acagttgata aatatcgata aaaaagactt cttaatcttg aaaaatctct
    11221 taggaaaatt gaagtacagc agctatataa aagtagtgaa ctattttgtc aatacgattt
    11281 tttcagaatt ttcggagaaa gaaaaaaatg aaatcagtga gcagatacga aaaaatatgt
    11341 cctactgttc gttttcatcc gctgattgca aagaaaaaaa cgaagaatat gttgttcaat
    11401 tattaacgca aatttatttt ttctcccgta ttttcccata cgatacgact catttgacga
    11461 tccgtgcaac ttactttgca cagcagatgc aacaccgcca gatacgtcta tatgctggat
    11521 ttcgtgcaga acttcaattt tattccactc tactgaatca gaatctgatt tattatttat
    11581 ctagctatat cttttggatg cttatcggta atcctgaaat tcaccattat acttctgata
    11641 aaaaaatact gattatcagc gacttaagtc ttcgacatag tcaatatatt gaagaatata
    11701 tcagtgatat tcttgctgtg cataaaattc actctgagac aactgctatt actgaagatc
    11761 agctgtcgaa atacaatctt ctcgagtatg atctgatcgt tacgaatcaa cccattttga
    11821 atgcccatgt tcctcatata ttgattgatg atagtgtgtc attcgcaaat gaagaagaac
    11881 tcatccgctt attcgagtta tgaataatca aaaaacagct atgtataaac caccctgata
    11941 aaaatttcag gacaaataca catagctgtt tctttttatt gtattccttc agcaatccaa
    12001 cgagatttat agcgaaagtc ttttaacaac tcttcttttg tccaattatt tgcaatgaga
    12061 tccgtcaaag tgttcattac gagggtcatg gaaaagtata ggaaactaac tgcttcttcc
    12121 gacgattgaa tggagaaatg attgattctt aataattcca gccatttttc gttcattgga
    12181 gaatcagccg atagttctct acgtttggtt gtctgctgat catttcgctg ggttaacaag
    12241 tataaccttt gccaatagat actttcgtga tctaagtcgc agcaccactc taaatatttt
    12301 tcgatcccca aaaagaaatg ttgtttgttt tcgctaatga attttaagat atcttgatgg
    12361 actatgtgag aactgctttt gatcgtatac aaataagcat cttccaaatc ttgaaaatat
    12421 ttataaaaag caccgcgcga catccccatc ttgtcaacga tttctgagac tttgacttgg
    12481 ctgatgtgct gtgagcaaaa tatctccagt aataggtcat cgattctctg tttctttgcg
    12541 ttcgataaat tgaaaaaagt ttcttttggc atccacatct ctcctttatc tctgattata
    12601 cgtggatagc ccttcattgt catgaaggat tcattccttc tttttctctt cttctgtcaa
    12661 gtacccatct tccattcgat aaacgcgatc actccattga atcatacgga catcatgagt
    12721 aaccataata gtcgcttttt gtttctcatg agcttcttta actagtaatt tgacgacttc
    12781 atatgcatga tctgtatcca aactagctgt tggttcgtct gctaagatca agcttggctc
    12841 attatataaa gcgcgagcaa ttgccactct ctgtctttct ccaccagaaa ggtctttagg
    12901 ataactattt ttaagtgact ggatatctaa agattgcagc aaggaatcga tttttgttga
    12961 atcttctttt tttgaagtaa cttggtcaac tagttcaaat tgttccttta ccgttaaaaa
    13021 aggaatcaaa ttagagcttt ggagaataaa tcctatttct ttaaagcgta aatctgctcg
    13081 ttttttttct ggaagctcag ttagtgagtg accgttgatc actatttctc cggaagtcgg
    13141 tgtttgcaat cctcctgaaa tggtaaggaa agtactttta cctgaaccag aaggaccaat
    13201 gatgctgacg aattctcctt cctttacata aaaatcaatt gctttcaaag ctgagacctt
    13261 tgtatgacca gaaccaaatg ttttggtaac ttttttcatc gttaatattt ttttcatttt
    13321 tattaacctc ctattgctgt aattgggtct actttggtta tcgtacgtat cgaaaacaat
    13381 ccgcctagca ttgcgacaat gatcaaaatc ccactatata gcaaccattg tgaccaaaaa
    13441 acagcaaaag gcatcgcgct tggtaaaatc agactagtca aataagcaaa caaaagagca
    13501 agcagaacgc ctaccacccc aacaataaag gactgtgcta ctaaagattt agcgatgaag
    13561 aaatttttga tcccttgtgc tttcattact ccaaaaatag cagtcttctg aagtgtcatc
    13621 acgtacatga aaataccgac cacggcagca accactaaga acaaaaagta tatcatcgca
    13681 tttaaggtca tattttgggc agaatagcca ggaatacttt caatgaatgt cccaatagtt
    13741 aataactgta gacccttcga tgctttttct ttcgaaattt tagctgaatc ctttattacg
    13801 atcccattga tcggctgttc ttcttcagaa gcaaacggct gttgtccata cttcaaagca
    13861 gtccacgtat ctagggacgc atagatgacg ggagaaactg tgtaataagt ttcaggaaag
    13921 ataccgacaa tcgtcaaagg atcgtcgtaa ctgccaattt tgatcgtatc tccaatttta
    13981 tagcctgaat cagccagatt ttgagagatg atgatttcat tctttgtttt aaattcatgc
    14041 cctttcgtga gttttggtaa taaaaatgct tctttcgttg tgccgaaaac tgtaacattt
    14101 tctttgtttt ttcctttgat tgctccgctg tacaatccga ttggtgcttt ctctcctcct
    14161 tcaatgtatt tcagatctcc tcttgttaat tgtgaagctg caaatacttg atttgcatcc
    14221 tccgacaaaa caatctcttg tgcgtcccaa tcatcgattg cttttttaaa ctcttctgaa
    14281 agtccattcg ctagtcctga caacatgaat acgacatacg caatcaagaa cataataccg
    14341 acgatcaagc catatcgtaa tttagaatag cgaatttctt tgatagctag aaacatttgt
    14401 ttttcctccc tatgatagat tgatagtgac aaaatgtcac ttgttgaata gtgtaactct
    14461 aaagtgacaa tttgtcactt gtgttgtttt tttcttatca ataaattgtc taagacatct
    14521 ttcgataaaa ccttaacatg agtcataaaa aatttattta agccttattt atgctttcca
    14581 tgataaacta aagtgaccaa atcaatgagg tgggaaaatg attaaactat tagtagtaga
    14641 agacgataaa gtattatcca ataatataaa agaaatactc gctgcaatcg gcgagataac
    14701 acaagtttat gatggtagtg aaggactgtt cgagttggaa agtggagttt atgatcttgc
    14761 aatcttggat ttgatgatgc cggaaatgaa tggatatgaa gtgttagcaa aaatacggaa
    14821 agaaaaaata cagactccag tattgatttt gactgcaaaa gatagtttgg aagataagat
    14881 tgaaggattt gaacgaggtg cagatgatta tctaacaaaa cctttctatc gagaagaact
    14941 gatcatgcgc gtgaaagcat tattgaaacg ctcgctaggt ctctttgatg aaaatgttct
    15001 gaagtataag gatatcagtt gtgatttaaa aagcaatgaa gtcttgtata aagaacaagt
    15061 tttgcccata caaggaaaag agtttgaatt gctcgtttat tttttacaaa ataagggaat
    15121 cattttgaca aaagagcaga tatttgaccg gatctgggga tttgattctg atacgacgat
    15181 tacagttatt gaagtttata tgagcaactt acgaaaacat ctgcgaagta ctggattgga
    15241 taaagaaatc aaaaccttac gtaatgtcgg ttatatactg caaagggtgt gatgcaatga
    15301 atggagatat tacacgaaag caacgtagtc gcttttttgc gacaaatgta gcagcatttg
    15361 cttttatctt ttttcttttg ggattcatta ctttacagat attaaaccaa tctgcataca
    15421 gagaaacaga tctgtcatta gagaaaataa attttgattc tcgaacagta caattagaga
    15481 tacaaagata tcagcaaggc gatccctttt taaacccgac tcaaacggaa caaaacagaa
    15541 caaacatgga acagccatta atggaaccat caaatgaccg ttttaacact caagtgatct
    15601 tgtggtctaa aaatggtgag atattgaata aagcagctat tggtgggcgt ttcaaccaaa
    15661 tcaaagaatt aaaaatggat acgaaaaatc tgaataccat ccaaaatatt gaattaaatg
    15721 aagacagtgg ctcatctgcc ctctctttcc gttcgattac gaaaaaagcg gagacgaatc
    15781 aagatggcgt tgcctacatc caaattttag aaaatacaaa tcaaatcaag aattcattag
    15841 cgacttttcg cacgattatg attttgtgta tgattgtttt ttggattctc tctattggta
    15901 tcagttatta cttgtctagt ctaagcatgc gccctattat tctttcttgg agaagacaaa
    15961 aagaatttgt tgagaatgct tctcatgaat tgcgcacacc gttaacgatt attcaaaata
    16021 gtttggaaca tctttttacc aagcctaatc atactattat tgaagaatcc gaaagcatcg
    16081 ctcaagcatt gtcagagacg aggcgcctca ctggattgac ttcggatttg ctgacaatcg
    16141 ctcggaatga ttctgatcag cagctgcttt caaagcaaat gatcaataca caagaatata
    16201 tcgaacaact tgttaaacca tttcaagaga tggccatcat agatggaaaa gagtttattc
    16261 tccataacga tgcaacatta gaagtaccaa ttgatgaaaa aaaaatccat caagttttgg
    16321 ttattttgct ggataatgca ttaaaatata cgaatccaga agataagatc attttggatt
    16381 catctgttaa ccataaagaa tggctgattc acgtaaagaa tactggccct tctatcagtg
    16441 aagaagatca agcaaggatt tttgatcgat tttatcggga agatcaatct cgggcgaaag
    16501 agactggcgg atacgggctt ggcttggcaa ttgcaaaaca ggtaatcgaa cagcatcatg
    16561 gacagatttc tgtatccaat tatcttccac aaggagtcga ttttaaagtc caattgccgt
    16621 tgaagcctaa aaaataatgc ttatccctaa aaaagggctg tgacaaaaat cttgtcacag
    16681 cccttttttg ttgcgaataa acggtgttcc agaagtagct tcttcggaaa taagccgaaa
    16741 tttctttaag ctgaccactt ctgtcacaac ctctttagct tacgcttacg attttttatt
    16801 gcggtcttca atgtgtacat caccgcttgt gtcaatatcc aattcttctc ggctaacatc
    16861 ttctgtcact ttttcaacat cttcatgttc ttctttatga atcccaactt cttcacgaat
    16921 aactgtatgt ttgcttacat ctacttgctc ttctttgatt gggatagtaa tcgtgtcatc
    16981 ttccaatttt tcgtctgttc cctgtgaaga ttgatctgtt actggtttgc gttcgatgac
    17041 gatttcttca cgtttgaccg gtacttctac cgtttcagta tcgttgacca catgtttgtg
    17101 gatgtcgact tctccagttg tcacatcatg tgtatttaca tctaattttt cttcttttag
    17161 ttgaattgta tcatcatcta gatttggttt gcgatcgatg tcttcagtct tgcttgtacc
    17221 cattgtatca gtctcgccag gtacgtccat cggatcagtt cctggtgtca tattcaatgg
    17281 atccgttgta ttttgaaagc ctgtcgtgcc acctacgtcc attggatctg ttccagtgcc
    17341 agtttctaat ccagtcccca ttgtgcttgc tgggctaaca gtatcttgtg tatccattgt
    17401 atcttctgtt gtttctggct gacgatagcc ttttactgtg atgacaaatt ttccatcaga
    17461 aatatctcct ctatattgat ataaaggatc attttctggt gtagccgtct cagaatcata
    17521 ggtatcaaaa gaaaaagtat cttttatttt ttcccataaa gaacggtctt cttcaccatc
    17581 catccgattt tcatctgttt caacatctat accagacaat ccgtcaaatc ctagtctaga
    17641 tgctgcttca tcagtagtat aaataacgat atcatctcgt tcataccctt cgttacgcaa
    17701 ccgttcaatt actgataatg cttcttccct cgtactatag cttccgatga ccgttaaatt
    17761 tttctcttcc atgtaaattc ctcctagcaa atagatttat gattggtata ttgttactta
    17821 taaatttatt ctataggaga cgattgtttt ctacaaatat ttagattgga atttgattaa
    17881 aacaatttaa ttgaaatttg aaaacattta tgttaatgaa agtcatattc taataaaatg
    17941 tcatttgttt ctatatgaat ttttatgaaa aatttcatat aatttccact cgttgtgatg
    18001 gtttaattta tccaatccat caataagcaa acaacttata taaaaaagga ttaattctca
    18061 atataattgc tcctaccata gaataaatct tcatgtaaag taatgaagta ccaactattt
    18121 ctaatacttc tttaagaatt atcccaacaa tatcgttaga caaaccatta ttgaataaat
    18181 ggagagccaa tcgattctga aaaaatgttt tctaattttt cggaaataaa agaaagagcc
    18241 tcctgccatt agaacgaacc aaatccattt cattgctcat gaagtaacca catagctaaa
    18301 aagaggataa atcaattaaa agatcaaaag aatgactgca ctaataaaat aactaaaaat
    18361 gtatcttctt acttcatatc ttttagctag tacttagtta aaaatttgct tcctaagatc
    18421 aagacaaact gtctatcttc atttgatgaa atgcggtaaa atatagaaaa tgaacactat
    18481 tggagggaat ttgtaatgga cagcaaaact agaaaacaac tgcaagaaaa gttaaagcaa
    18541 cgtacacact tgctcccttc cgtctttcaa cagtttttag aagaaaatcg ttcttccctt
    18601 tcattaggca gtcgctatga atacgcaaaa gattttcatc tgtttactga ttatttgaga
    18661 aaagtatttt ctgaagaagt ggatgatcag ctgattatcc atttagaaaa acaagattat
    18721 cagaatttct tagctaaaat ctatcgacat actcgttcgt tccaaactac agcgaaccaa
    18781 gaaacggagc aattgtttga aaatagctat tacgggattt caaggaagca atattcatta
    18841 aatcattttt tacgattttt gtatcaaaaa ggactgattg aagaagagat ttctcttttg
    18901 ggtacaagtt taccggaaac aaccaaagca gctccgcgat atatcgatgc agaacttttc
    18961 aaagattttg agcatttgtt tatcccgatt gaaggctttc aaacaagcag agaagctagc
    19021 tttgaagaaa agaatagacc gaggaacctt gcaattactg ccattcttct gtattgcgga
    19081 ttaaagatcc atgaagtagt agaacttaaa cgtaaagatg tatctttgac caagcagatt
    19141 cttaatctga atagaaaaga aaacagactg aataaagtac caataccaaa agaagcgatg
    19201 ccatttctgg agaactattt taagttaaca gcacaaaata cggacgaaaa ttcttttgtt
    19261 tttcgttcct cacatgatca gcaaatttct cctcggacta ttcgccaaat tttgagcaaa
    19321 attacagtat ataaaaacgt atcgccagaa ctatgcagaa aaacatatcg ttattatgca
    19381 gaactatatt tagatgatgc tgacgcggta aattatttat gtggtaatcg atacctctca
    19441 tcccattctt ttcaagatat ctgggaaaag atggttgatt tttcttatca cgaattagcg
    19501 gcattcgttc gggtttcttc catataaaac aaatgtatga tctttttttc acaataaact
    19561 atgttattat ataaaggatt atgttacgat tatcttgaat ttgtatatta cttaacaaaa
    19621 gataatggag tgtgaatgat ggagaccata acgtattccc ctttgaactt atttacgaat
    19681 tttcaagaag ctgcagctaa cttttccgag accccgatta tctttgatga gccactttca
    19741 gctttcccag aattaggact tgaaacaact tacaaaaaat gctgcgaaag tgtgttgaaa
    19801 cgggcttatc aattggctca tcttggagtg aaatccggag acaaagttat tatttataag
    19861 agttccgctt ttgacacata ccttctagct gtttctgtgt cttaccttgg tgcagtgcct
    19921 gtcatgactt cttatcatct accaacaaca acaatggaag tatttatcga tcgtttagaa
    19981 gaccctttca ttttatttga tgatgagaca aaaaagcgag tgagagaaat ttcaaatgga
    20041 acaaaatcaa aacagattcc tattctttat ttaatggaac aacctgcttt gtctgtttct
    20101 caatcatttt tagacaaaaa tgaaatttct tatatgaccc atacttctgg tacaactggt
    20161 atccctaaac ttatttgtca ttctgctcat tctatgggat ggcggacgaa atggcaaaaa
    20221 acagttttca caaaaatttc ggaaaagaaa ttaatcgctt ttcacatctc tccagtgcat
    20281 tccagattca atattggtat ctcttctttg atgtccatgg gatttcctat gatgccttta
    20341 gcaaacgcac aaagttcaaa agttgttcat atgttggaag ctcaccggcc aattgcacta
    20401 gagacccatc cgaataactt tgttcagtgg cgttttactg ctaaggagca tccagaagct
    20461 ttttcgggta tccgatacta tcactccact tttgatgcta taaacaacca gacaatgaag
    20521 acatttttgc gaacgtcgat ggcacaggat gcggtatttc ttcaagtata tggccaaagt
    20581 gaatgcggac caatgattct taaggctcat acactagaga gtttgaaaac aagtgatgca
    20641 agagatatgg gcgttggact ggaagacatg acaagcgctc ggattacaga ttcagttggg
    20701 aatgtcctac ctgaaaacac agatggtcat atacaattac tgtctaaagg acgggctttg
    20761 acttattaca aggaagatgc acggttccag gaaaatgttt atggcgattg gtgggatagc
    20821 ggagattacg gttttatgga taagcatggc cacctatttt tgaaagatcg gcaagtggat
    20881 ttgatcgaaa cgatcaatag tacattagct attgaagact ttttattaga ttcgttagat
    20941 tttttggcag aagtagtgat tgtaagggat aaaaatcatt ctccacaacc gattattgct
    21001 ttagctcctg ataaagaaat ggattggaat cgatggtggg agcaagtcca tgaacttcct
    21061 cgcttgaacg tccctatcat ccgtgatttt gatgcaatcc cgcgaacagc tacaatgaaa
    21121 gtgcaacggc ttcaaatcga gaaagaatta aaatcacaaa agtcctaact atttaaggaa
    21181 agaaagatcc attttggtct ttcttttctt tttgtttttt taaattggat gagataaaaa
    21241 tatgccaatt ggctgttttt cttttttgaa aatttcgtta tactcttatt catggaggaa
    21301 aatgttatga aaagaatctt gacaattggc ggttctgatc catttgctgg tggaggaatc
    21361 caaacagatt taaaaacttt tgagaatttt ggtctattcg gactaagcgc cttgacttct
    21421 ataggggcac tagatattaa tgagcgattt atgctggaat ctatatcttt ggaattgctt
    21481 aaacgacagt tagtttcgat tgataaaatg acttcattag atggtatcaa aattgggtta
    21541 ttgaattcaa gtgaagcaat catggttgtt cgagacttca taaaaacaaa acaaaatatc
    21601 ccaatcattt tagaccctgt tttggcattc aaagaaactg aagctgtgat caatcaattg
    21661 tatatttcgc agctcatcga agaacttttt ccacttgtta cgatgattac gcctaatttg
    21721 gcagaagctg ctttactttc tggtcaagct cttccctctt cgttaacaga aatgatccat
    21781 ctcgctaaag aactcactgc ttcaggaaca aaaaacattg tgatcaaagg cggcacaagg
    21841 atggctggag atgaagctgt ggatcttctc tattcaattg atcattatga ggtattttct
    21901 cataaaaaaa tcgacactac aacagtaaac ggggccggtt gtgccttttc ttctgcaata
    21961 acagcgaatc ttgtgttagg ggcagatttt accaaagcag tagcagaaag taaaaaattt
    22021 gttgcccatt gtatttctaa tggcgtgctg atgaacgatc ataccggaag tgtctggtct
    22081 ggcggtattc aaaaaggagg aatgagaaat gaaaactaag caattaacga tctatgctat
    22141 gctgattgcg ttgacagttg ccctttcatt aacaattttg atccctgtac cggctacgaa
    22201 tggatttgtg acattatgcg aggccgggat ctataccgct gcttttcttt atggtccaac
    22261 gggtggatta gttgttggtg cttccagtgg tctattgatc gatttgattt caggatatcc
    22321 gcagtgggca gttttttcat tagtgatcca cgggttacaa ggatatgttg ctggttcttt
    22381 cagcaaatct tctactcgta tgtggggatt agggctttta ttaggaagct tagttatgat
    22441 catcggctat ggtatcgccg gttggatttt atatgattgg ccggctggag tggcttctat
    22501 accaggaaac atcttccaaa atctgattgg aatgggactt gcctttccta taactgcaag
    22561 tcttcaacgt attcaagcac ggaagcaata ttaattgaaa aagaaggttt tagaaaatga
    22621 agttgtcaga aaaagaatta aaagaccaat tgactgaaat agttaatgac atattggctg
    22681 aggcacactt gaaaaaaggt gatctttttg ttttaggatg cagcacaagc gaagtcgttg
    22741 gaggacatat tggaaaaaat tccagtgcgg aagttggtca atggatcatc cgtacgttaa
    22801 aagagttgtt ggatcctaaa gaaattgcgc tagctgtcca aggttgtgaa catttgaacc
    22861 gagcattagt agtagaacga acagtggcag aagcaaaaaa tttcgaaatt gtctctgttg
    22921 ttcctgcact acatgctgga ggtgcttgtt ctgttgctgc ttttgaccag ttcaatgatc
    22981 ctgtcgaagt ggaacacgta gttggacaag ccggtatcga tatcggtgac acatcaatcg
    23041 gtatgcatat caagcatgtc caagtacctg tcagacctcg tttgaaaacc cttggacaag
    23101 ctcacgtgac agcccttcgc tctcgtccta aatatatcgg tggtcctaga gcgaattatt
    23161 gaaatgagta attgacagag caatctgaaa aacttcctcg caaagtccaa ctaatgaact
    23221 ttaacgagga agttttactt gtttgtttta tataaccgag cttcataagg tgctagtatg
    23281 cctttagctt caaattctcc gctagaggaa tttgacaaga gtaatgtcca ggactgatct
    23341 gcttcttttg gaagttcata gtcagcaagt gattctgtta agtttaccat aataagatat
    23401 tgttcatctt ctaaatatct ttcatagaca taaagttgtg gatgttcatg aagatattct
    23461 ttataagaac cgtatatcag acctttattg gtttgtctaa tgcggatcat gttcttatag
    23521 aattgcagga ccgactctgg ttcatattct tgttgttcta cattgatcgt tttggtattt
    23581 ggattagtga tcagccaagg ttcatgtgta gaaaaaccag catattgttc cgaagtccat
    23641 tgcatgggtg tcctgctgtt gtctctcgtt gtttcacgaa tgatatccaa tgcttcttct
    23701 cttgtcttac cttccgcaag cagcctttta taaagtcttt tcgaatctac tgcatcaact
    23761 tgatcgatcg attcaaaggg catattcgtc attccgattt cctgtccttg ataaataaat
    23821 ggcgtacctt gcaaaaagaa atacatcata gcgattgctt ttgcagacat agcccaaaaa
    23881 tcgggacgag tatctccaaa cactgaaacg gcacgaggaa catcatggtt ttccatatat
    23941 aaagcgttcc atccgatacc atccaatgaa gtttgccaag cgcttaatgc atgtttcaat
    24001 ttaaggacat ctaattgccc ttctttttct tgctgccaga tatggatatg atcaaattcg
    24061 aatatcatat cgaaataacc gtctttccct acccattgtg gtccttcttc tgcagtgaca
    24121 ccacttgctt ctccgacagt catgatatcg tactcttcaa aaacatgttt caaatcggtc
    24181 aaatgttctt cgattcctga gacattttga aagggtgaga aagggttctc tgtggctttt
    24241 actgaatatt catctttttt tacatgagaa atcgcatcta aacgaaatcc atctatccct
    24301 ttatccaacc accatcggat catattgaat agttcttctt tcaatttctc gctttcccaa
    24361 tttaagtctg gttgttcttt tgcaaaaaca tgcagataat actgtccagt ttcatgagaa
    24421 tactcccaag cagaaccgcc gaaaatcgat gtccaattat tcggttcttt gccatctacc
    24481 ccgtcgaccc aaatgtaata atcgcgatac gggctttctt tagatttttt cgattcttca
    24541 aaccattgat gctgatccga actatggttg atgacaagat ccataatcac tttgatccct
    24601 aattcatgtg cttcttttag caataaatca aaatcttcca tcgttccgaa tctctcttct
    24661 atatcttgat agtcacttac gtcataacca ttatcgacaa atggagattg atagatcgga
    24721 ttgatccaga taaagccgat accaagatct ttcaaataat taagtttttc acggatccca
    24781 ttgatgtctc cttgaccatc gccattgcta tctttgaaac tagcaggata gatttgatag
    24841 cctactgctt ctttccacca tttttgttct tgtatcatat cgtttcactc ctttaacggt
    24901 ccctcttgat tataaccgat tctattttag aagtatcctt gttaccggta actagaaacg
    24961 aaaagctcaa cgaatctgct aagtgcgttc gctgagcttt attttatcat agatagcggg
    25021 caatcagttg aatcatttgc ttgggaaatt cattcaagtc agtaatatct acaaaacgac
    25081 tttcaccgta gatcgacttg atttcttctt tgtcttggcc aatagctgcg gagacaaata
    25141 ggattccttg acgttcatat tctttcaaaa cagactggat atcttctttt gcttttttgc
    25201 ctgtataatc cggcaacgct tttggctgac cgtcactaat attaagcaac agtttggttg
    25261 ttgcggattg tctgtttaat ttttctgctg ctaaacgaag tgcagcacca tcacgattgt
    25321 tttgccttgg tttcatagtg actaattttt catttaacca ttgaaatccg tcttcaaatt
    25381 ctttataaga aaacaaagaa gtcttttctc ttgacgaacg gtctgctgta tctccgtaaa
    25441 tcaacaatgg gatatcgact ttcttagaaa attcggcaat ggcaatcgct gctttttttg
    25501 ccgcttcgat ccgatcatcc cgtatcattg acccagattc atcgatccgt acagctaccg
    25561 ctaaagaagg ttgctcatgt ggcgggttct ttttgtcaaa atttctcaaa tcaccatatg
    25621 ctactttgct tgcattgaac cgctgacctt cgtattttcc tttttggtac gtctctgttt
    25681 gttcattatc cagtaactct aaaatttgcc ggctaagtga ttctactatt ggcattactt
    25741 gcatgtgtag ctcacgtgct tccggcgttt ttccttggaa agctggtcgg tgaacgatga
    25801 gaccttcttt ttcatgaatc gtttccttca tgatttgtcg cgcttcttta ttcagttgct
    25861 tcttgatttc cttatcatgt gcttccatgt cagaagcaga catttcttga gaatcatctc
    25921 ctgtttgttg ttctttttga ttttttcctt cgatatcgct actgcgttct ttttgcattt
    25981 gaggaggaat ctcgtttttt tctattgttt cttcttgttt ctcttctccc tcatttggtt
    26041 cttcagcaga caacgatttc ttttcatcta agcgcagaat ttcttcagca ttttcagtga
    26101 tgtttcgttc atttgcttct tcggcgctaa tggttctttc ttttgtatgc tcagattgag
    26161 gatgacccca tttttctttt ctcaatatgt cctgaagttc cagtagcaat ccactgtcag
    26221 acaaagcttg ttcaagaatt gccaattcat ctgaatcagt ggataattta tacaaaactt
    26281 ttggataaat cgactggagt aaatcttgtc cttgcttata ggtatttgcc caataaaaat
    26341 aagaacgcat tcctgctaca cctttgatgg cgttagcttt tgcagtttca tccaacaaac
    26401 ggataatctc tgccatcttt aagagaagtt cttgtttttg gatcatagtt ttcgccatcg
    26461 cacgttctgc catgacttct aaggcaggaa gatccatttt ttccgcatgt tgcatccgat
    26521 ctcttaaaga ttcatttaat gggcgatttc cttggtaatt tcgatttgta gtgatcacaa
    26581 tgacgcaatc tggatggcga cgaatgattc ctgtcggtaa attcaacatc ccatttggtt
    26641 cgagcgctga gttaagtgcc acaagaacag aggcatctcg gatgacagtc ggctcttgaa
    26701 tctctaataa atagcctttt tcaatcgctc gaacgatttc agaagggtaa tagctgtaat
    26761 ggattgcatc tggataatca gcttcgatcc tttgaactag ctctgctaat ttttctttag
    26821 cagaaaaagg atcaatgccg taatggttct ggatcagtgt cagtacagct tcaagtgtat
    26881 ctgtttggta aatagcttct agtaattctt ggtcttgttc cttattagaa tctactacag
    26941 gtaataaggc tccgaaaaca tctgatttgt ccatatctgc aaaacaggtc acttttgtat
    27001 agggaagttg cagatcagca gatagtgctt tggctaattg tgtcttcccc gacccggcat
    27061 ctccttccaa aagtacgtta ctgattttca tttcaggatc ttgccaattc cctttgattt
    27121 cggaggcgat ccgccattct tctgcacttg tccgatggct tttcggtttc ttccagatca
    27181 tttgcttttc tagccgtgaa aaggttcggt tttctgttag tgagaaattc tccatgcttc
    27241 tcttcccctt ttgatcatct ctgtctatta atatcctagc tcatctaaaa gacgttttaa
    27301 aatacggaat cgttccccaa tcagttctcc gtctttttgt agtgtatcgt aatacaaaat
    27361 gatgtcttca tcgatctttg gatttttggt atctacttct accgtcattc ggttcccttg
    27421 taatccaatg atgtctacga ctggattttc tggatcataa aatttttcat aacgataagc
    27481 atcttggaag tataaacttc cttgcgcagc taagatcgct aaatctaaaa tacgtgtgat
    27541 tggtaattct tccgactgtc gtgaccattt ttctccagta tgtcgccata ccttgcctga
    27601 gatatcgact tttccacgat cattccactg agcaaggccc agtgaaagcc cttttgcatc
    27661 catatttaat gcatttcttc catcaacttt atcatagtct tctacaacga ttactggttt
    27721 atgttttaaa tttgttggta tttccattat tttaactcct catcctttta tttttagtaa
    27781 ataagtaaat tagtagttta ctcatttact aaactatatg cgacattata gaggattgaa
    27841 gtgaggattg caaagaaaaa gagcttcatt gatagaaata aaaacaccat ctcgttcttt
    27901 tacacgctca ttagtaacat gtagaaagtc caagatgatg ttggaatatt t
//
LOCUS       DAIGTA010000038        27130 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.038, whole genome shotgun sequence.
ACCESSION   DAIGTA010000038 DAIGTA010000000
VERSION     DAIGTA010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.038"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(144..1622)
                     /locus_tag="NOB43_001719"
     CDS             complement(144..1622)
                     /locus_tag="NOB43_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982575.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1920..2855)
                     /gene="murB"
                     /locus_tag="NOB43_001720"
     CDS             complement(1920..2855)
                     /gene="murB"
                     /locus_tag="NOB43_001720"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCI0982576.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2928..3848)
                     /locus_tag="NOB43_001721"
     CDS             complement(2928..3848)
                     /locus_tag="NOB43_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0982577.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3961..4713
                     /gene="xth"
                     /locus_tag="NOB43_001722"
     CDS             3961..4713
                     /gene="xth"
                     /locus_tag="NOB43_001722"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCI0982578.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5577..6110
                     /locus_tag="NOB43_001723"
     CDS             5577..6110
                     /locus_tag="NOB43_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HCI0982579.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6600..7124)
                     /locus_tag="NOB43_001724"
     CDS             complement(6600..7124)
                     /locus_tag="NOB43_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0982580.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(7117..7590)
                     /gene="tsaE"
                     /locus_tag="NOB43_001725"
     CDS             complement(7117..7590)
                     /gene="tsaE"
                     /locus_tag="NOB43_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCI0982581.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7713..8693)
                     /gene="pta"
                     /locus_tag="NOB43_001726"
     CDS             complement(7713..8693)
                     /gene="pta"
                     /locus_tag="NOB43_001726"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCI0982582.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8846..9526)
                     /locus_tag="NOB43_001727"
     CDS             complement(8846..9526)
                     /locus_tag="NOB43_001727"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI0982583.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9652..10521
                     /locus_tag="NOB43_001728"
     CDS             9652..10521
                     /locus_tag="NOB43_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0982584.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10547..11062
                     /locus_tag="NOB43_001729"
     CDS             10547..11062
                     /locus_tag="NOB43_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982585.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(11109..11702)
                     /locus_tag="NOB43_001730"
     CDS             complement(11109..11702)
                     /locus_tag="NOB43_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0982586.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11727..11906)
                     /locus_tag="NOB43_001731"
     CDS             complement(11727..11906)
                     /locus_tag="NOB43_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982587.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11983..12492)
                     /locus_tag="NOB43_001732"
     CDS             complement(11983..12492)
                     /locus_tag="NOB43_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982588.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12588..12968)
                     /locus_tag="NOB43_001733"
     CDS             complement(12588..12968)
                     /locus_tag="NOB43_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0982589.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13298..14047
                     /locus_tag="NOB43_001734"
     CDS             13298..14047
                     /locus_tag="NOB43_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HCI0982590.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14231..15508)
                     /locus_tag="NOB43_001735"
     CDS             complement(14231..15508)
                     /locus_tag="NOB43_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982591.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15587..16231)
                     /gene="pcp"
                     /locus_tag="NOB43_001736"
     CDS             complement(15587..16231)
                     /gene="pcp"
                     /locus_tag="NOB43_001736"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCI0982592.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16430..17374)
                     /locus_tag="NOB43_001737"
     CDS             complement(16430..17374)
                     /locus_tag="NOB43_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCI0982593.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17376..18062)
                     /locus_tag="NOB43_001738"
     CDS             complement(17376..18062)
                     /locus_tag="NOB43_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCI0982594.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18536..18856
                     /locus_tag="NOB43_001739"
     CDS             18536..18856
                     /locus_tag="NOB43_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCI0982595.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            19010..19915
                     /locus_tag="NOB43_001740"
     CDS             19010..19915
                     /locus_tag="NOB43_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0982596.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19912..20685
                     /locus_tag="NOB43_001741"
     CDS             19912..20685
                     /locus_tag="NOB43_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0982597.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20866..22290)
                     /locus_tag="NOB43_001742"
     CDS             complement(20866..22290)
                     /locus_tag="NOB43_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0982598.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22501..22947
                     /gene="nrdI"
                     /locus_tag="NOB43_001743"
     CDS             22501..22947
                     /gene="nrdI"
                     /locus_tag="NOB43_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI0982599.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(23012..24994)
                     /locus_tag="NOB43_001744"
     CDS             complement(23012..24994)
                     /locus_tag="NOB43_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0982600.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(25008..25904)
                     /gene="murQ"
                     /locus_tag="NOB43_001745"
     CDS             complement(25008..25904)
                     /gene="murQ"
                     /locus_tag="NOB43_001745"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI0982601.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25907..26968)
                     /locus_tag="NOB43_001746"
     CDS             complement(25907..26968)
                     /locus_tag="NOB43_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI0982602.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
BASE COUNT         7943 a         5591 c         4729 g         8867 t
ORIGIN      
        1 aaaatcggaa taataactta tgtacttttt aattttgtta agtaatatat ctagttatat
       61 ctagttatat ctagttacct tttctttgaa aaaaacataa atcagctaat aaatatgtga
      121 gacaaagctg ccatccataa atactagctg attttttcag ttaaatgtct atttttttct
      181 ctgatgatgg tatttccaaa atattcccag tcatctggag tcggtggatt tttccaaatt
      241 atctgttctt tattaaattt ttcaagtaaa caatcagata aataaatatt cgtacgagaa
      301 gtgattcgac tctcaatcac aatattgtaa tttttaaatc ctttcacttg agaaataatg
      361 taatcggtat aagcagatcc ttgcgaaaaa tcaatacaga catgaatcgg tgcttcaaaa
      421 tatgataccg gacaaatacc gaccaataaa aagagataat cataaaataa gcgaatcatg
      481 aaacgttcat cttttcccaa gaaatagcgt ttattctctt gtatgacctt ttggattgct
      541 gtactgaata ttggatacgt ctcgaagaaa aactgtagct gctttttaga cgtaaagcta
      601 gtcatctcaa agtcgaatat ccaatttttt cgattgacat gcatcatacc catacgaagt
      661 tcttttcgta tatatagtct ttcttcttca gagatttcaa tcgaaaatgg taattgatca
      721 atcaattcca ctgacatttt ttgactaatc atgtggatat catgaaaatg agcttccgca
      781 agtccaaatg cgccatctaa ttcaaattct tcttccgtga tcaaaaacaa catgatataa
      841 gaaatctcat caatgatctg ctctttaggg atatgaagaa aagaaatatg tgataaatcc
      901 ttgatgatct tcattccttc tgagctctta aagtattcat ctgaaaagaa acgttttccg
      961 attggttgat tcccataggc cctcaacaaa ctaatagtgg ttagcaaatt gaatttgatt
     1021 cgttttgttg cagacagttt taaattgaac agatattcaa aatattgcac gatactcttt
     1081 gcttcattca tgacgctttc tctaaatggc atagaaaaac cattaaagac cccgaaatat
     1141 accccaaata atacgttccg tatgtttatt tcttccccaa ctaatatgtt tttctttaac
     1201 tttatttgat gctgttcaag aaaagagact aattctcttc tttttacata ggctcttgat
     1261 atgcttaaaa aatgattctc tgcaaatttt tcgatcgtta cttttgaatc cacgatctcc
     1321 gttaacagtc gagcaatttt tgatcgttga aagtagattc ttcttaaatt tttgatatcc
     1381 gtcaaattca gacgttcgac atggatctct gcttcttctg aaatttggat ctctggcttt
     1441 gttttgaatt cagtaaattc tttatttaat tctatgatat aatttcttgt tttaaattta
     1501 gacaaaccta atgtttcata taacttaggc agcactacat aattcttttt ctcaaattct
     1561 aaatatctag ctagcagcag tttttctcta tcttcctctt ctataaggta atccaacttc
     1621 atatcctaca cctcaaaaaa tgcctcatac caattacttg atatgcagat gaaagttcat
     1681 cttttcacct atactgattt tatgatggat tatgcttgtt ttttcatcag ttattctcat
     1741 tttttatctt ttttttgaga atattgcaaa aaatggaaaa atttatgagg aaatattcta
     1801 tattttttgt tttattgtgt taaaatgtac aagatttgcg ccatttgcgt aaacaaccac
     1861 aaaaaagagc aggacggcca ccgtcctgct cttttactta ttttaagttc cattacttat
     1921 taattggcta aacttctgct tgtttctgat attgcttgtt tttctccaat gatccgcact
     1981 tctgtttcta aagacacatc aaatttttct ttgattactt cttggatgtg cgcaatcaat
     2041 tcaatataat ctgtcgctgt cgcatgatcg atattgacga tgaatccagc atgtttttca
     2101 gagacttgtg caccgcccca tttcaggcct tgcaatcctg cttgttggat cagctgacct
     2161 gtatagtgtc ctactgggcg cttaaagaca cttccgcatg aagggtattc taatggctgt
     2221 tttgattgac gcaattcggt caactcatcc attcttgctt tgattgcttc ataatcccct
     2281 gtttgcaaac tgaatcgagc ttccaatacg atagcacgta attcttggac tttactgtga
     2341 cgataagaaa ataccatttc gtcttttgtc aaagttttca atgttccatc ttcaagcaaa
     2401 agatccactt cagcaaaaac atctttgatc tctccgccat acgcacctgc attcatataa
     2461 accgctccac cgacacttcc cgggatgccg caagcaaatt caaatccagt caatgattct
     2521 gccaaagctg cataagtcgt atcaatcagt gaggcacctg cttccgcaat gaccatcgtt
     2581 cctttgacat gaatctgttt catttcagtc agcatgatga ctacaccgcg aatcccgcca
     2641 tcttgaacga tcagattgct tgcatttcct aataccatcc aaggtatatc atggattcgg
     2701 caataatcga tgatttgctt tacttcttct tgttttttcg ggaatgcaag gacatcagct
     2761 ggtccacctg ttttcgtaaa cgtatagttc atcaatggtt catcaaacaa tatagtaatc
     2821 gtggctaagc tttcaactat ttcttcttta ttcactgagg attttccttt cttttctcaa
     2881 acgtcctcat tattctatca cgcttaatac aatcttgcca gtcttgttca aagttgatga
     2941 cggtagtgat ctttaagcac ttcctcacat aattcatgac ttcttacaac ttctttttgt
     3001 ttaagcaatt ctgtttccga tttacctaaa cggatctgag aaaagaaggc ctctaccatt
     3061 ggctcaaacc cgcgtttgac tagcgtgttt gtccagtcgc caaattcttt cacttttttt
     3121 ccatcagcat cttgaatgac aagctgggtc agatcgttta cttcataagt accattttta
     3181 cttgttactt gatatttttc tatattagcg ccacttgcta aatccatcgt taaaatagcc
     3241 gtttgatttt gtgtttctaa ttgtaaaatg gcatattcca aaaattcctt tgtttctctt
     3301 atctggtatt ttgttctcaa aatgggttca tctaataaat acacagctgt atcaataaga
     3361 tgtaaaaaca aatcataaag gacgaactct gtcgtttctt ttgccgctat tcgatttttt
     3421 tgcaggtgga tcaaccgctt atctgggata cgtttcaatt cttctaccat aggagcaaag
     3481 cgccggttga aaccgatcat caaaattatt tggttcttat cagctaattc ttgcaattca
     3541 cgaacttcat ttagatggac actcagtggt ttgtcaatat aaacatggat accattttct
     3601 agacattttt tggctaattc ataatgtact tttgttgctg cgtggatcat acatgcttcg
     3661 attttttctt ctaaaagctc atcgatcgtt tcatatagat gttggaaccc gtactctttt
     3721 tgaattcttt cttttgtttc tttatttctt gttgcaaaat aaaaatcaag tgttccttgt
     3781 tttttcgcat aagttggtaa atatgctttt tctgcgatat tccctacacc gattacacca
     3841 atcttcatct actttcctcc tggatcattt agttactttc atcttacacc attttttact
     3901 aaaatgaggt acaatagtat cgcaaaggta aggaaattaa ttcgaaggag tgtgctttta
     3961 ttgaaattta tctcttggaa cgtaaacggg cttcgtgcca tcgtaaataa aaatttttta
     4021 gaagtttttc atgagttaga cgccgatttt ttctgtctgc aggaaacgaa actccaagca
     4081 ggacaaattg atttagatct tccaggttat tatcaatatt ggaattacgc ggaacgaaaa
     4141 ggctattccg gcacagcgat ttttgctaaa aaaccagcat tgaatgccac ttacggaatg
     4201 ggtatcgata tccatgatac agaaggccgt ctgattactt tggaatattc cgatttcttt
     4261 cttgtaacct gttacacgcc aaattctcaa agcgaattaa aacgtttaga ttaccgatta
     4321 gaatgggaag aagcctttta taattatttg gaaaatctaa aaaaacaaaa accagtcatc
     4381 gtgtgtgggg atctaaatgt cgctcatcaa aagattgatt tgaaaaactg gaaaacgaat
     4441 caaaaaaatg ctggattcac tccagaagaa agagcggctc tttctcgact gttggataac
     4501 gggtttatcg atacattccg ttatttttat ccaacccagg aaggtgtcta ctcttggtgg
     4561 aactaccgat tcaattcaag gaaaaacaat gctggttggc ggatcgatta ctttttgacg
     4621 agcaaagatt tagagccagg actagctgat gcaaagatcc atacggacat tatgggcagt
     4681 gatcattgtc cagtagaatt agatttgaaa taaagaggtt gtgaaaaagt cgtttagttt
     4741 cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat tttgcataaa tttggcataa
     4801 taccgagaaa ctggcttttg aacactgttt atcgagagat tgtgaaaaag ctgtcctgca
     4861 tcaagtaata agaacagcca aacaaaaata gttcctcata tttttcgttt ggttgggctt
     4921 attaccgcag atacaagctt ttgaacaccg tttattaaga ggttgtgaaa aagctgcact
     4981 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atatttttcg tttggttggg
     5041 cttattaccg cagatgcaag cttttgaaca ccgtttatta agaggttgtg aaaaagctgc
     5101 actgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt tcgtttggtt
     5161 ggacttatta ccgcagatgc aagcttttga acaccgttta ttgagaagtt gtgaaatcag
     5221 cgtcctgacc tgagtattag agaaacaaat ggcaaaatag ttcctcatat tttgctattt
     5281 tttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaag ttgtgaaaaa
     5341 gtcgcctact ttcgagtcgt aagaaatttt tttgaaaatg gttcctcaca actttgcata
     5401 aatttgactt aataccgaga agtcatgatc cccatctaac tccaaatcac aaggaatgag
     5461 ttcaaaaact agcttttctc aacaaatatt acataaaaaa ttctatgttt tttgttaaat
     5521 ttatttgctt ttttcaaaag tatgttacag taatttccca aggaggtttt acagaaatga
     5581 attttgttgc catggatttt gaaactgcca atcatcagcc ttatagtgct tgttctcttg
     5641 cgctagtcat ggtaaaaaat agccagatcg ttgatgaatt ctatacattg atacagcctg
     5701 agactccttt tttctggcga aatgtccaaa ttcacggaat ccatcaagaa gacgtacgca
     5761 atgcgccgaa attcccagaa gtctggcaaa ctatccaacc atattttcaa aaaaatcgtt
     5821 tagtcgttgc acataatgct gcttttgata caaaggtctt agcgggatgc ttagattatt
     5881 atcatcttga acagcctaat tatctttctt tatgtacagt gaaaagtagc cgtcgcctgt
     5941 ttcctgaatt tccaaatcat cgattgaaca ctgtgtgcga aaatttgaac atccaattag
     6001 atcatcacca tgatgcattg gaagatagtc gtgcatgtgc ggaaatcctg ctttatcaag
     6061 aaaaaaaatt cgggacagat ccattgaaaa aacttgtgac tataaagtaa aagaatactt
     6121 atgaaacaca caaagaggtc gtgagcctgc cgtttcactc cgagtcacaa ggagcaattt
     6181 caaaaaatag cttctcatgt ttattaaata ttgtgactgg tgaccgagga gctggcagga
     6241 gaacaccgtt tattggagag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
     6301 caaacaaaaa tagcttctca tatttttcat ttggttggac ttattaccgc agatgcaagc
     6361 ttttggacac cgtttaccaa gaggttgtga aatcagcgtt ttgacctgag tattagagaa
     6421 acaaacggca aaatagttcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
     6481 tgattgaaca ccgtttattc aaaaaaaatg gactgcgaca cgacttttgt cacagtccct
     6541 tcgtgtgttt ttctgccttc tcaaaaggat gacagtttct cactcttttc ctatttcttc
     6601 tattcaatca aataactcat tttatataca tctaaaaatt cacctagatc tgttcttgcc
     6661 cctctaggca tgaccgcttc gatttggaag cccatttttc ggtaaaggtg tacggctctt
     6721 tcattacgaa cttgaacgtc aagctccaat cgaaaaagta cacccatttc cttcgcccaa
     6781 ctgatgattt cttctagcat aagagtgcct agtcccattc cccaatattc ctgcagaata
     6841 ctgataccga cttctcccac gtgagacaaa cgaaattgac tgtctgcctt gacagatgct
     6901 gttccaataa tcgtcccttc atagattgca agcagcaata aattattatt gctttcgtat
     6961 atataatcca actcttcttc taaggtttct ggtggtaaca ggagttctgc ttcatccaaa
     7021 actaaaaatt ctgtctcctt attaacttgt cccatcatca aaagaatgtc ttttgcatct
     7081 cctggcactg cttcccgcaa gatgatccca acttcttcac tcatgatttt cagcccattt
     7141 ttctagaatt cgctgtttga aggtttcact ttgctccccg tatgagatta gtttcacata
     7201 ccgcttttct aaatctgtat cacttttttc taaaatcagt tccaaataat cctccggcag
     7261 tgcttcttct aatagatttc cccattcaac aacggaaagc ccatcacctt caaaatattc
     7321 atctaaccct aaatctgctc cgctagctgc tacccgataa atatccatat gatacaacgg
     7381 aatccgacct tgactatatt ctctaataat cgtgtatgtc ggacttttga tcatttgcgt
     7441 tatccctaat ccttgggcaa ttcctttcgt caacgttgtt ttacccgcac ctagatcacc
     7501 agtcaatatc agattgtcac ctggcattgc ggaatgacca attgcctctg cgaattgttc
     7561 tgtcattgtt aatcctgata gttcgatcat ttttcatctt ctcccgctct tctttctttt
     7621 tgccagtata tcgcgtaatg aagttttttt aaagaaaaaa tgaactagtc aagaacagca
     7681 gctgctgttt ttggctagtt cgcgtgtatt tgttaatcaa tcaatgtttg tgctgctgtg
     7741 ataatcgata atttatatac atcttcttca tttgctccac gagacaaatc agaaaccggt
     7801 ttgttcaagc cttgtagaat tggtccgatt gcttcaaagt taccgaaacg ctgagcaatt
     7861 ttatagccga tatttcctga ctgcaattct ggaaatacaa agactgttgc ttgaccagct
     7921 acttctgaat ctggcgcttt cagttgtgca actgaaggaa cataagaagc atcaaattgc
     7981 aattcgccgt cgatcatgta ttgtggcgct agttttttag cgattttagt tgcttcaact
     8041 actttgtcta cttctggcga tttcgctgag ccttttgtcg agaagctcat cattgctact
     8101 tttggttcga tatcgaacaa ttctgctgtt tttgcagaat ctacggcgat ttcagccaat
     8161 tcttgcgcag ttggattcac gttgatcgca caatccgaaa agacatattt ttcttgatct
     8221 cttccacgta ccatgatcat cgctccgctt gtccgactga tgccaggctt tgttttgatg
     8281 atctgaagtg ctgggcgaac agtgtcgcca gtcgaatgga tcgctccaga gaccattccg
     8341 tctgcaatcc ccatatacgt aagcatcgta ccaaagtaat tcacatcttt taaaatcttt
     8401 tctgcttgtt ctttggatgc ctttccattt ctacgttcaa caaaagtatc caccatttca
     8461 tcccacttat cgtaattatc agggctgatg atcgtaaagc tagatgtttt gattcctctg
     8521 gcatgcgctg catttcttat ttcttcttcg ttccctacta aaatgggttc cacaagttct
     8581 tctgctttca accgggcagc tgcgcctaaa atacgagcat cagtagcttc cgggaaaacg
     8641 attttgatcc cacggcgaac aattttaaat cttaaactat caaacaattc cacaagatga
     8701 cctccagacg tttttatatg tattatcata cactattcca gaaaaaaaga acagtttatt
     8761 ttatctgtat cagtcaaaaa tgctggaaaa attaagtttt tcacatacaa agcgaactgc
     8821 actataacag gaaagcgctg ttttattaca ctgtttcagg cagttgccaa tcaatcggtt
     8881 cttctcctaa cgcaaggagc gcatcattcg ttttcgagaa gggtttggaa ccaaaaaagc
     8941 cacgacttgc agataacgga ctgggatgtg gagatgttat gatgatatgg cgactcttat
     9001 cgatcatttt gattttttct tgtgccggtt ttccccacaa gataaacacg attggttttt
     9061 cccgttcatt taatttttca atgatcgtgt ctgttaatct ttcccaacct ttcccgcgat
     9121 gagaatacgc ttgcccttcc cgaacggtaa gaacggtgtt gagtaaaagg actccctgtt
     9181 tagcccatga cactagattt ccatgttgaa caggtgcgat tccaagatca tcataaagct
     9241 ctttatagat atttcttaac gatggcggga tctttacgcc aggttgcaca gaaaaagata
     9301 agccatgagc ttgattttct ccatgataag gatcttgtcc taaaatcacc actttaactt
     9361 cttcataagg agtcaattcc aatgcttcat agatatgata catatctgga tggatctttt
     9421 gggacgcata ttcttttttt aaaaattctc ttagatgcag ataataatct tttgaaaatt
     9481 ctgaggacaa aacttcttgc caactgttat gaatgatttc tttcaaaaac tccacctcct
     9541 aataaaaaga ataactcaca ttttcttcaa tcacaaggga caatcttcac cctcagcact
     9601 tgattaatat ggtaaactag gaacaagaag cagaaaggaa cgataatcat tatgatcaaa
     9661 ttaattgcat cagatatgga cggcacatta ttagatgccc atatgagtgt ttctcctgaa
     9721 aatgccgagg cgatacgttt tgcaaatgat gccggtgttg agttcatggt cgctactggt
     9781 cgaaactatc aagaagctcg cgcagcttta gatgaggtag gaatcgattg tgcgatgatc
     9841 actttgaacg gggcacaggt atttgataaa gaaggaaatt cattgtttac cgtgtcgatt
     9901 ccaaataatc aagcaatctc tgttttagat attctagatg ctaacggtat ttactatgaa
     9961 gtagcaacca acgatggtct ttattctgaa aatcaagcga aacgaattga aagttttgct
    10021 tccatggtgg ctacccattt acctcacctt acgtataaaa tggcgattgc catggcctca
    10081 gctaagctgg agttattgca catcacatac gtggacagta ttcgtgctat tttggaagaa
    10141 aagaatctgg aagttttaaa aattatttgt tttcatacag aagggccagc tgtattaggt
    10201 ccagttggaa agcagatttc tcttttaggc gatctagccg ttacttcctc tggtcaaaac
    10261 aatatcgaag tgaaccataa aaacgctcaa aaaggaattg ctgttgccca tgtcgctcac
    10321 gagcgtggga tttctttaga agaagtcatg acgattggcg ataacttcaa tgatgtcagc
    10381 atgctgcaag tagcaggagt cagtttcgca atgggaaatg cagaaatcga agtaaaagat
    10441 tatgccaaat atacaacgga cacaaacctt gaatctggcg taggaaaagc catattgcgc
    10501 gcgattgcag aagacttgta gttttatcta gaaaagaggg atatagatgt cagaattttt
    10561 cattcaggaa aagcagcttg gacgtgcaac tcggacaatt gtcaaaaacg aaaaaggaca
    10621 ttccctgttt ttgatggttg gtcgctgggg aacaaagggc gatgcattgt ctctttatgc
    10681 catgaatggc gatctcgttg ctcacatcaa gcagataagc ctgacattcg gtacgcgttt
    10741 tgagctgtat aaagagttcg aaaaggtggg aaccatgcag aaaatattca attggcccgg
    10801 tgacttttat tatattcgta gacttcactg gacagtccaa ggtgatatct ataatcatca
    10861 atatcaaatc catcatttca atcagcaaat catgaaaatg gataaagcaa cacttttttc
    10921 aggagattac tatgtattgg atgtctcaaa tgatgaagat gctccagttt gtatttgtat
    10981 tgctgcggtt ttagattact ggctctaccg taaagacaaa agtcgcgata agcctgtttc
    11041 ttaccgactt aacttaagtt aaaaagatgt acctgaaatg cggaaatacg catttcaggt
    11101 acatcttttt agatattctt ttgcatatga tcataaagat gaccactgat catccgctga
    11161 ccgacaactt tgaagtcatg gcgttcgtat aattttttag cctttggatt tttttcatcc
    11221 acacttagac cgatgacgga gcgattagct ttcttcgcca atttaggtaa tgcttctaat
    11281 aatcgcgaac cgatgccttg tcctctaaaa tcttctgata cactgataga gtccaaatac
    11341 cattcgttgg gaaacgtttc tttatcaatg aacaaacgtg tagacgcatc tagctgatat
    11401 ttctctaaga taggtaccag tggctgatcg atgattgatt cttcttcatc tgtataaccg
    11461 taagcaactc ctgcaacttt accgtctatt tcttctacga tacctcgtga ataactgtaa
    11521 cgataatttg gatcagtgat tgcttcttct aaaatctcta aagtcttttg ttcccctgtc
    11581 tgcttcaaaa atggcagttc catatctttt agaatcacta agatcaatgg ggcgatttct
    11641 ggagcatctt cttttctcgc aaaacgaatc atagtttcct ctccttttct ccattctaac
    11701 atgcagaaaa agaaatcgca aaatcgttat tttaaaaaat cttcaatctt ttcagtaatg
    11761 aaataaccat gagtaacgat tcttgccgct tcagttcggc aataagggca gacgactggc
    11821 atttctttat cattatgttc gactacatta ttgacttctt cgtatgcaaa tttttttccg
    11881 caattagggc atttcatttt ttccatgtta tctcaacttc ctttcatctt tactctctta
    11941 gcttactctt atattgtaaa aaagagaagc aatatccttc ttctatgcag atatccatac
    12001 ctgacggtcc tgttctccat ctattaatcg gactttataa taaggacgtt catctttgac
    12061 tagaagtgtc cactctttca cttttgcttt tttcccgtag tagctgactg cttccttcat
    12121 cgctgcttgc ggttgtttga actcttccgt tttttctata tcaaaaagat gttctgcggc
    12181 cttttccgtg tcatttcgta cggttgtttt cccagtggat ggattgactg ctatgacttg
    12241 tccttcacaa aaaaactggt attcatatgt tgcattcgta ggattctcca aatctttttc
    12301 aactgcaaaa tgaatagcag atatgttatg ttcttttgtt tcgtttttta cgattgctgc
    12361 tgcttttttc aatgagatcc gatattcctg gtcactaata tcatccatgt gaaaagcggc
    12421 attgagcagt cccgtcatac cggtaatccc tattacgatg agggcagcaa caccaaacat
    12481 catttttttc attcttcatt ctcctgtttc ttttttttaa agaatatcaa gaaatgaacg
    12541 aatgaaaaat cgaatgaaac gaaaaaaaag tgacaatttt gttatcttta ttcgtgcagt
    12601 tctaatggca atccgtctgg atcaaagaaa aacgtcattt tttttcctgt aaaggtatct
    12661 tctctaatcg gttctgattc gatccctaag gactgcaatt ctgcaattgt ttcttcaata
    12721 tcgtctactt tgaaagcaag atgacgcaag ccacaagctt ctggatagtt tggtcgttgt
    12781 ggcgcattag caattccaaa aatctccaat tcagcacttc ctagtttcag atctaattta
    12841 tagtcatctc gttctttgcg gtaattttct ctgattactt caaatcctaa tttattaaca
    12901 taaaaatcac gtgatttctg ataatctgaa acaatgatgg ctatatgatg gatcgttgta
    12961 aggttcatat gagcactcct attcttcgtt taagctcgga tctatattaa tctccagttc
    13021 cattgtaaat gtgtcagatt gaaaaaaata gctgtttttc ctttttataa gaaaaaaggc
    13081 aaaaaaaaca gaaagtaggt cctccaagac actcttcctg ttcccaatat aataaatgaa
    13141 agtaagaaat tatattttca agaaaacaaa cagaaaatta tcataacaca aattatttat
    13201 aattgaaaga ctagtttttt ttcaagaaaa gcatacaata gattgtgtta gtaaatacag
    13261 aacacactac atttagtgtc ttaaggagtc ctcatacatg aagtcatatt ttcagttttt
    13321 agctcatcag ctaaaaggct ggccgcaaca aaattattat cttttctttt tcagtcttgg
    13381 ctgccaggtc atgactcttg tcaatagtcc catcacttgg ctgtccgtta ttacatttat
    13441 cggtaccacg cttggtgtat tgtgtatttt atccatcaat gcggcaaaat cagtcaacgg
    13501 tattttaggt attttgtctg cgatttgttt tattatcgtt gggttttcag caaagaacta
    13561 tttaagtatc ggtgaacaga ttgcttatat gatcacattg gatatccccg tattgttaag
    13621 taaagaatgg aatcataata tggcttcaaa aatccgaaaa ttcactggaa aaagctggtt
    13681 tatcgcaatc atcagtactt tccttgtcta tcttgtttca ggattcctga ttggtcgtta
    13741 tacagatgat cctcggccgt gggtagatgc cattgctttt tctattagct tgactgctgg
    13801 tatcatcagt ttcttgcgtt acaacaacca atattactgg tggttagctt cagggcttgc
    13861 tcaaatggtc ctttggtata tttcatttac gcatggatct gcaagtttgg cgatgttcgt
    13921 gaacagctct gtttacttgc tgaatgatgt ccttgcattt accgtttcac cttggtataa
    13981 ccaaaaagaa cgtgaacgta tgcaaaaaat ggaagaagaa tactacaacg cacaacaaca
    14041 cgcataaaaa aactgagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac
    14101 acgtataaac ggcggaatca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat
    14161 ttgaaaagca attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag
    14221 cctctatttt ttatagtaat tccttcagat actttcttgc ctcatcattg aaacgcagtg
    14281 attcttctaa cttctgataa tattccaacg cttgtttctg agcttcagta aaacgataat
    14341 gttttccttt ccatttgtcg attgtctctt gcacatttcc agattggata tctttcacta
    14401 ctagttgcca tttttctttt gagactgtac ggtctttctt atcagcagat tgtatagctt
    14461 ctcgttcttt acgcaatact tttaaaaaac catttctgac tatccgagga atgctgtcga
    14521 agaacccttc tgtaaaacca tagcgacaat attgcttcca aataaataga tagatttttg
    14581 gttggatgaa tcgttggttt ttcgcaaaat attccatctg agcagtgact tctggtgttc
    14641 gttgacgttt tgtctttctc aacacggaaa taaatgtttc aaaataagca ttaggatgta
    14701 ctggcacttc ttcatatacg atggattgcc aatctttacg taaaaatgcg cgatagttga
    14761 tcaagaattc ttctacatcc tttactaatt cttctgcaaa gtcgtcaaat agttcttttt
    14821 ttatctgtcg cttttttgac tgcccattga tgtgttcact tattttcttg atttcatttt
    14881 ccaatgcttg ataatccgct atgtaaatcg gcatttctac ttggcgaaat tctgcgagcc
    14941 gctgagctaa ttttatatcc ggtaaatatg gctgtttcat ccgacgattt tggtacaaga
    15001 caaaacagta tttttgccat agtccttcag gaaaatcgat attcttctgc ttaagccata
    15061 ataattcgtc taaggccaga tcaacttttg tcattccctg atggatcgaa gctgccactg
    15121 tcggagagac atgcaggtga tcggcaaagt ggttgatgcc tagttttagg atctttccgg
    15181 tttttggcga tttaacgatg tattgcactt ttaattctct accacactca caatacaatt
    15241 tttgctggct tcgttttgtt cgaaaaaacg gattgatctt gaagtcagaa aacacccaat
    15301 ctgttgcagc taaataatgt tcttccataa aacgagagct gattagatat cggcggtgct
    15361 tatcgactag ttcccgctgt tttttcgtta attttgcata gatctcccaa cgttgactgc
    15421 ttgtgtattg tttagaaatt ttgatgggat agcttttgct gatttctttt ggaaaccatt
    15481 cttcaaagac ggattgccat tcttccacgg ctgtttcttt cctttctaat tacaaaaagc
    15541 tggctactaa cataacgtta gcaaccagcc agtgtttctt gctaaattag tgagttgttc
    15601 cggcatttcc ggaaatatct tctttatttt ctactgctgc ttcaactgca taagtcaaag
    15661 aagaagcaat gtcttctaaa gacatagaag gcgtacccac tggacgatcg atcacttgat
    15721 cgggtgagaa tggcacgtgg atgaacccac ctcgaattgc cgggaattgt gtttcgatca
    15781 aatgaagcaa acgatacatg atatcattgc agacaaatgt tcctgctgta taagagatgt
    15841 acgctggtag accatgatct tgtacatttt ttgtcattgc tttgattggc aatgaggtaa
    15901 agtaagcggc tggaccgttt tcttctaaag ccgtatcgaa tggctgattt ccttcattat
    15961 cagggattct tgcttctgct agattgattg cgacacgttc gaacgagact gctgaccgcc
    16021 cacctgcttg tccgacacag atcacgacat ctggttggtg ctgttggatg gcttctttga
    16081 ctacttgact gcttttttcg aatacggtcg gtacttccac tttgatgatt tcagcaccgc
    16141 tgatttcatc tggcattttt tttactgctt cataggctgg attcactttg tccccaccaa
    16201 atggatcaaa acctgttact agtactttca tctgttgttc ctccgtccga ttgatttaac
    16261 atatggttat cttttatcat accattttcc ttgaacagcg taaataaagg aaacaatagt
    16321 ttaaataaca taacagatca aacttaatat attcttataa aaaaatagtg ttccactaca
    16381 atgttagaag aggttgcgac aattattctg tcacaacccc tctcttctat tatttaaata
    16441 gaatcatata agcaatttgg aaaactagca taaataacgc aataaacaac tggtttttga
    16501 tcactccgta tttgtctttc atctccagca tcgctacagg cacgatattg aagttagcag
    16561 ccatcggtgt cagcagggtc ccacaaaaac cgcaagtcaa tgcaaccatt cctattaacg
    16621 ctggattcgc tccatgacta aatacgaatg gtgcaccgat cccaaccgtc atcacggtga
    16681 tggccgcaaa tgcattcccc atgattaccg taaatatcac catgccaaga gcgtaaatga
    16741 tgatgccgat gttcacattt ccttctggaa cgatcgtacc tactgcattg gaaatcactg
    16801 tcccaactcc agcgcttgta aataccgcac ctagagaagc taaaagcatt ggcaacatgc
    16861 ttaacggccc tactgtgccc agcatatctg ctgcatcatc taaaaatgta cttggtcgat
    16921 tatctcgaga aaagaacatc aagattagca tggctgcaaa aacaccgacg cccacgccga
    16981 ctaaagcacc taaattggta aatagagcaa acaagatcgc aaagacaccg atactcaaag
    17041 ctggaataaa aattttcatt cctagtttgt ctgacatttt ttccatatat tcttttgatg
    17101 gaagccggct ttctcctttg ctgactttct tagcaattgc tggtatggtc atcgcaaaga
    17161 tcaagccacc gttcacgatt gccggaagcc atcttcctcc tgcaataact acccctaaga
    17221 ccgtccagaa aaaggctgac ccataacgat gaggattggt tttatctgtt aaatttctta
    17281 ctccagtgta aatcaatacg agtcccatca cgatataaag gatctccagt aatttatcgc
    17341 ctaataaaat atcaggattt gtaaaaaagt ccatcttatt gcccctttcc tggataatat
    17401 ttcttcgcta atttcttttc tttaagatag aagtagacac ttgccacaac taaagccgtg
    17461 atagccactg gaacttccac taaagcaagc tgtcccaatg ttacgtcata tcctagatct
    17521 ttcagtgttg attggactag caacgcccct gctcctccga tgaatagtac ttggccaaag
    17581 aaccagcaga cattttccat agctgaagcc atacctttta gttcttcttc atgcttagga
    17641 tggacttcta acccttttga ttcgatggtc cccaatgcca tcggtaaaat gattggacga
    17701 acaaatccag caactccacc aaaactcacg ttaaaagccg caaagatcat tcgaaagatc
    17761 ccataaatat ctacaatcat accagcagat actttcttga atcgcttgat caaggaagcc
    17821 gctgattctt tcagaccatt tctttcaagc gttcctgttg ccaacataat gatgataaaa
    17881 atcgccatcc cgcgattgtt tacaaaactt gtacctaaaa gttctaacat tccttgaatg
    17941 ccaagaccgc cagtcaaagc tgtaacaact aaagcaacca ttacgatcaa tatcgagtct
    18001 aatttaaatg caaacccgag aataacaatc aagacgccta aaaggctaag ataattttcc
    18061 atatattttc ctccataaaa tgacaatatt tttttaatta taaagcaaaa cacataaaaa
    18121 atatagttgt tttctcacga aatagacact atttttaaat atttttcgtt atttttttat
    18181 cacaaaaatt atcttactta ttgtaaggta aagctttttt taatttattg cccgataata
    18241 tatagaaata aggtctagtt actgtttttt ttaaatgatt aataaataac aacttctttc
    18301 tatgaaattg caaagcattc atcttctttt ccgctaacga tatatccgtc agtgcttggt
    18361 acactttact aaaaagtatg agattgccga tatctggata ggtgtgctat actacagaaa
    18421 aagatataca atctgccacc gggtaggata aagaggatga tcattccatt aggtctttga
    18481 agggatgatt ttcctctttt tgtgtatttt tttatagtta aggaggaatg taagtatggc
    18541 atggatggaa ttaatcatag caggaatttt ggaagtattc tggtcaacga tgatgaaatg
    18601 gagtgatggt ttttctaaaa tcaattattc tttttacaca gtgattggca tgattgctag
    18661 tttttacttt ttgtcaaagg caatcaaaag tttgccgatg agtctctctt atcctatctg
    18721 gacagggatt ggcgcagttg gttcggtcat aattggtgtg gtcttgtttc atgataagct
    18781 gaatctttcc acttggttct ttgtggggat gctactcatc agtatcattg gcatcaagat
    18841 tactagcggc cactagacac ttggaataag tactgatcag aaaaaataag cctttttatt
    18901 taatattcaa tttttttatg aaaaaataag aaataagtcc aatgacctag cgacttctcc
    18961 actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt tgaaaagtct
    19021 ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg atgtcagttt
    19081 tagcttatcc cctggcaaaa tcgttggatt agtaggtcct aatggcgctg gaaaaacaac
    19141 gatcatgaaa gctattttag gactgatcca ttactcagat ggaacaatct gtattggtga
    19201 aaatgagatt tctccctcta gtcataaagg gttggaacaa gtaggagcat tgatcgaata
    19261 cccgggtatc tatccattct taacaggcta tgatcatctg aagttattct ctgaaaccaa
    19321 cgatgtatct gctatcgaca ctatcgtgaa tcagctcaag atggaaaagt acattcacaa
    19381 aaaagcgaaa tcctactcgt tgggaatgaa acaaaaattg ggaattgctc ttgccttact
    19441 gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc cacaagcaac
    19501 aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt tcttgatctc
    19561 cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga tcaatcaagg
    19621 aaagatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag atttcatcgt
    19681 tatctctaca acaaatgatc tagctgctcg aacgatcttg acagaagctg gatatacttt
    19741 ggaagatcct gataaaatca agcttttaaa agaaaacgaa gaattattag gaaccgtgat
    19801 ccagctattg tctgcacaaa atatccatgt gacagacgtc cagcatctga cgaatgattt
    19861 ggaatcttct ctattggaaa ttctggattc agtaaagggg gaagaagaaa aatgacattg
    19921 cttgtaaaac aagaattatt taaattgatc aagaaaaagt caactgctgt tttatctgtt
    19981 ctattagttg ttttgctcat aggaacagca cttctagcca aaaaatacac gacgatcatt
    20041 gatccagttg aaatgactgc tcagcttttt agtgccacat cttggattgt ctttatcatg
    20101 attgcagctg caagcacgat catttcgatg gaagcacaat atggtacatt gaaaaatctc
    20161 ctttatcgaa agtattctcg aggagaaata ttagtaagca aatggatcac attagttatt
    20221 tattctgttt atttatacct tttagctatt attgtcactg tgttgatgaa actgattctt
    20281 ttcccttcga tttccttcac ggagaaggtt tctactggtc aaacactgat ccaaagcttg
    20341 ttcacttata ctttgggtag ttatatcggt ttatggctga ttttaagttt agtgttgatg
    20401 attgcttgct ttatcaatag ttccggcgca tccatctcag caggaatcgt cttttatttt
    20461 gcttcgtcaa tcatatctgg tatccttatt gcactcatcc aaaaatggga gtggatcaaa
    20521 tggaatccga tcagtatgtt gaatctgcaa aaccaaattg gaaacgaaga gatcatgaag
    20581 caattgactc atctttctac taatcaaatg ctattcggta atttagctta catcgttttg
    20641 ttcttagcat taggatatct cgtatttaag cgaaaaaatg tatgatgact catcaaaaaa
    20701 gaggctgtga aagagacgtt cagccttatt gccgattggc tgtctcttaa acaccgttta
    20761 ttctgaaaaa ggagctgtga caacatttgt gtcacagctc ctttcctagt atgtttttga
    20821 ataaacgaca ggctcacaac ctctctttat acttctttta tacttctata cgtgaagcat
    20881 cccagtggca aataaaacca ttgcaatcac tccgaccatc gtcacaccta taagtaaaat
    20941 cttatctaag tggatatgtt gtacaggctc gttttgctcc ttacgtgctt tgaggtaaaa
    21001 ataaatgcct ggcaagaaaa gaacaagaac aagcattact tcattaaagg ctacgactag
    21061 catagcccat acttgaaagg cacttgctaa aagccctact aaaaattgga cccattcttt
    21121 ccgctgataa gaaagtttca tttggtacaa tcctaagaaa agccacgtga agaaaatagc
    21181 tgctgtacca agtgtgtaag caaagttata agcactgtca gtgaataata atgaaagtaa
    21241 aaagacattc gtacataacg tcgtcaatac gatagcataa gttggtgccc catttttgtt
    21301 gagttttccc catgctttag gcaaaagtcc gtcttcagcc atgtttccca ttgtttcaat
    21361 cggtaagatc gtccatgaga gccaaacacc aactaaagaa atgatcaaac cgccgttgat
    21421 cacgactgct ccccatttac caaccatcat ttcaaacaca tagcccatag caggctgcgc
    21481 cttgatcgtt tgcagctgat tcatcgtcat tgtcccatat ggaagcatgg aaaccaagac
    21541 gtaaataata atcaagccga atatccctag aatcgttgct ttcccaacat ctgattgttt
    21601 ttttgctcgt gaacctacga cagaggctcc ttcaatacca acaaataccc aaagcatcac
    21661 catgatgcaa ctcaatactt gactggaaaa cgggatcggc tgtccattcg cattcaatat
    21721 aatgtcgcta gaaaagttat caatgaattg ttggatcgaa aacgtgctga tagctactac
    21781 aataaataaa aataatggca ctaatttaca gaatgtgacg atagcattga cgaaactagc
    21841 attttcgact ccccgattca ctagccatgc atatccccat aaaaagactg tactcatcac
    21901 gatcgatgcc agattttgcc caccttcaaa tactgggaag aaatatccta atgcgctcat
    21961 caacaatgtt gcaaaagcta cgttgcctaa ccagcatgtg agccagtaac cccaaccgct
    22021 gataaaacca gcgaaacggc caaaaccttc ttctgcgtaa ctaaagatcc cgccttttaa
    22081 atctggacgt tttttattga tattattgat cgacaaggag agcatcaaca ttgctgttcc
    22141 tacgagtacc caactgaaaa tagctgggcc gccagccgat ccggagatgt ccgtcataat
    22201 accaaatacg ccacctccaa tcgctgaacc aattactaag gcagcaagtg gaattaaacc
    22261 aattcctttt ttctgttgct ctgtatccat gtaagcatcc tccaaaataa aaccgctttt
    22321 atcaaaaagt ataacaaacc ttttttattt ttacttaatt aataaaaact ttaatagaaa
    22381 tataattcta ccggcttttt tctcattata caagcaaagc gcctagtccc tttccaaatt
    22441 acaccaccaa aaaacttaaa aaagatgcta tactaaaagg aaagaattgg aggatgatcc
    22501 atgaacattt tatatatatc gatttcagga aatacgcgtg cctttgccaa acatctagca
    22561 gaatatgctg aaaaaatgca tgcagaagat cctgtcaatc ctgaagttac tttaaaagaa
    22621 atccatgaaa atagtgattt tacgaaagaa acagaaccat tttttacttt cgttcctact
    22681 tatttagacg gcggaaatgg tttagataac ggtgatacag aaatcttgac cgaaacgatg
    22741 cgtgaatatc tggaacatga agacaatcat aaactttgtc ttggtgtagt cggtagcgga
    22801 aataaaaact tcaataatca gtattgtcta acagccaaac aatatgcaca aacatttggc
    22861 tttcctttct tggcagatta tgaattacgg ggaacaccat ctgatgtgac acgaatttat
    22921 cagattttag cagaaaacaa taaataataa aaaagaagaa gctgaaaaat agatttcagt
    22981 ttcttctttc gtttctattg tttctatcat attaagcttt gacatccatc acaggtgctt
    23041 ttgcttttgc tttacctgtt ttttccaaga caaagttttt tacacgatcc atattggtta
    23101 ccaagacgat catggatgtt tctttgcctg ctgctttgat cgcttctaag tcagcttctg
    23161 ctacaagcgt atcaggtgtc acttgctgcc cttctgttac tttcacatca aatggcgtac
    23221 cgcctaagtc aactgtgttg attcccatat gaagcaagat ttctaaacca tttggcgttg
    23281 tgatcccaat agcgtgtttc gttgggaaga cagagctgac taccccagta actggagaat
    23341 agatatgtcc gttttctggt tctacaaagt agccttcacc catcatcttt tgtgcaaaaa
    23401 ctggatcact tgctttatct aaagaaacaa ctgttccgtc agcaactgat gagaggatag
    23461 tcacactttc agctgaagtt tgaggtacta ctttttcagg cacttcattt actgtggctg
    23521 tttcagtcgc taattcttct ttttctaaac ggtctttagg aataccgaag aagaatgtag
    23581 caacgaagcc accagcataa gctgccaata atccaaggat gtagcctaac catttaccgt
    23641 cagagatcaa tgggatcaaa gcggctcctg aaggtccaat agcgatagcc ccgacatttc
    23701 cgatcattcc gatcactgcc ccgccgatac ctccaccgat acaagcagta ataaatgggc
    23761 gtcctagagg taatgttact ccgtaaatca atggttcgcc gattcctagg atcccgactg
    23821 gtaaagctcc tttgatcatt tctgttaatt ctttatcttt tttgcagcga atccataatg
    23881 ccaatgctgc acccacttgt cctgcaccag ccatcgcaag aattggaagc aatagcgtac
    23941 gaccagtttc atcaatcatt tgcacatgga ttggagtcaa aatttgatgc agtccgaaca
    24001 taaccatcgg caagaataat gtgcctagaa cgaagccggc aaatgctcca ccaacgccaa
    24061 gtacccagtt gatcccaccg accatgccat cagaaatgaa acctgctaaa ggcatgatga
    24121 agaaaatttc aatcagaccg atggcaatca atgaaagagt tggtgtaacg atgatatcta
    24181 ccgcatcagg tactacttta tgcagttttt tctcaacgat tgacaatagc caaacagcga
    24241 agatgacacc taggatccca ccttgtccag ctgcaagagc ttcaccagta aataagtttt
    24301 tcagtggtgc ttccggattc atccctgtca gcatcacaac ggccccgata actccaccaa
    24361 gagttggtgt tgcaccaaaa acttgtgcag cattgatacc tgtatagata actaggtagc
    24421 taaacatccc gtttttcaag atgttcatca catcgatata ttgttgccat gttgctgcat
    24481 caagtgttcc ggctgtgact aagtttgcta aaactgcggc aatccctgcc acgatcccag
    24541 taccgacaaa tgcaggaatc attggcacaa agatattaga aatgtctttt aataccgatt
    24601 tgattttaga tggtttttgt ttcgattttt gtgccgcttt catttcttgt gcccgttcgt
    24661 ttacacggtc ttttccagat gctgatgaat ttgctgtagc tgtacttaca gaagaaagtt
    24721 tttctcctaa tttcacgcct gccaaatcaa ccatttgctg tgctactttg ttcactttcc
    24781 caggtccgat gatgacttga agctgttcat cttctactac accaagcact cctggaatcg
    24841 cttttaattc agagacattt acaagatcat cattgatgat cttcatacgc acacgagtca
    24901 tgcagtggac aatgctttct acattgccca tgccgcctgc ccctttataa atttgttttg
    24961 ccagttcttc caaagtcagt tcgttttttg ccatggtctt ttccccctca taaggtccct
    25021 tttacaaatc cgtttgcttc agctaatttt gcttgagctt cctctttatc actatttgtc
    25081 aaaatcatga cgatagccag cttaacattt tgatctgctt cttcaaagta cttttcagct
    25141 gtttcgtaat cagcttctgt cgcttgcatg atgattcgtt ttgagcgttc gattagtttt
    25201 tcatttgttg gtttgacatc gaccatcaag ttattgaata ctttacctat accaatcata
    25261 ctgatagtag aaatcatatt caagataagt ttttgtgctg ttcctgactt caatcgagta
    25321 gagcctgtca aaaattctgg acctgcatcg acttcgattg ggaaatccgc gtgtttactg
    25381 atttcggctt gtttattgca agaaatcgtt cctgtgacag caccgatcga ttttgcgtaa
    25441 tctaatccac cgatcacata tggtgtacga ccgctagctg cgataccaat aactatatca
    25501 ttttttgtca aattcagctt gattagatct tcttgcccta gctcataaga atcttcggcc
    25561 ccttcgacag ctacagtcat tgcttcttct ccaccagcaa ttagacctat gaccatttcc
    25621 ggttctacac cgaatgtcgg tacgcattca gcagcatcta acacacctag tcttccactt
    25681 gttccggctc ccatataaat cagacgtcca ccttttttaa aggactcaat cgtgttagca
    25741 atcactggtt cgatacttgt cagttctttt tcaaccgcag cggccacttt ctgatcttct
    25801 ttgttcatta gttgaacggc ttgagaaata ctcatctcat ctaatccaaa agtttcttgg
    25861 tttctgcgtt ccgttgttag gttctctaaa ttgattttgc tcatttttat cttccttctt
    25921 ttcttataaa ttgatagttc ataccagctt tgatttggtt gatcaatggt agctcttctt
    25981 tgataacttt agctactaca ttcacttttt catccgctgg caaatcatat ttggttaatt
    26041 ggatctcacc catatagcgc aaatactttt cgttatctaa agtaatagac cctttcatac
    26101 gcgtagctgt atttcttgct gggataggcg gaatctctcg aaaacgtgca tctacgcttc
    26161 gtatgacatc tcttgcatcg tcttgccgat tcgtatgctt ccctaatata tattcgtaaa
    26221 attcttcatc tacaggttcc gtatggagca agactgtctg ttctttttgg aaagaagcaa
    26281 attgctcctg aacgttttct gacagacctg catctccgat gtaaacaata tccgtgttac
    26341 ttgctaatag atctagagcg cctgcaagag gatggatccc tcgatgttct tccaaagttg
    26401 gcaatccttg atatagtggg cctctcaact ctgtatctcc tggtacaaaa ccttggacaa
    26461 ggagaccttg aattttgagc cattgatttt ttttctgata ccattctttg tccagccctg
    26521 tttcgggacg tggataataa ttatgccaag cttcaatctg tgagaaatca gcttctgctt
    26581 ctttcaattc atcgatatct ttaggcgtga tcgtgctagc attcaaactg attttcaatt
    26641 gatgtgacca gtcggcaatc tgctgattgg aaatatgata atccattctt aaacctgtta
    26701 caccaattgc tttcaaaggc gttagatctt ctaatgaaaa acccgctcgt tccaatgcct
    26761 ctcctgaaat atcgaccatc aattctagtt tattcttttt cgcttcgctt cctagttcga
    26821 tcaatcgctt ttgatatgcc gaaacatcat cttctggtat atgcatggaa gtgaaaatac
    26881 cgacaaagcc attggatgcc atttggcgga tatactgttt cttctcttct gacaaagaat
    26941 cgttcataaa tattgaaaag ccaaacatat tatccctctt tttctgtatc cgtcttcatt
    27001 tctatgacta gagtatatat ctaaagaaac aaaatttcaa tacttttatt aaaataatta
    27061 aatttcattt ctaaaggttg agtttatatt atcaaaagaa ttgtcataac ctaaaaaagg
    27121 cactgctaag
//
LOCUS       DAIGTA010000039        26873 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.039, whole genome shotgun sequence.
ACCESSION   DAIGTA010000039 DAIGTA010000000
VERSION     DAIGTA010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.039"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..411
                     /locus_tag="NOB43_001747"
     CDS             <1..411
                     /locus_tag="NOB43_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0982603.1"
                     /translation="GLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAP
                     QEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLA
                     ELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
     gene            509..697
                     /locus_tag="NOB43_001748"
     CDS             509..697
                     /locus_tag="NOB43_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI0982604.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(755..1108)
                     /locus_tag="NOB43_001749"
     CDS             complement(755..1108)
                     /locus_tag="NOB43_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982605.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            1639..2061
                     /locus_tag="NOB43_001750"
     CDS             1639..2061
                     /locus_tag="NOB43_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0982606.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2058..2288
                     /locus_tag="NOB43_001751"
     CDS             2058..2288
                     /locus_tag="NOB43_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982607.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            2786..2986
                     /locus_tag="NOB43_001752"
     CDS             2786..2986
                     /locus_tag="NOB43_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI0982608.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3013..4206
                     /locus_tag="NOB43_001753"
     CDS             3013..4206
                     /locus_tag="NOB43_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0982609.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="NOB43_001754"
     CDS             complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="NOB43_001754"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI0982610.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(5898..6821)
                     /locus_tag="NOB43_001755"
     CDS             complement(5898..6821)
                     /locus_tag="NOB43_001755"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI0982611.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7017..7622
                     /locus_tag="NOB43_001756"
     CDS             7017..7622
                     /locus_tag="NOB43_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0982612.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            7930..8946
                     /locus_tag="NOB43_001757"
     CDS             7930..8946
                     /locus_tag="NOB43_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0982613.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            9087..10388
                     /locus_tag="NOB43_001758"
     CDS             9087..10388
                     /locus_tag="NOB43_001758"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCI0982614.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            10434..11096
                     /gene="deoC"
                     /locus_tag="NOB43_001759"
     CDS             10434..11096
                     /gene="deoC"
                     /locus_tag="NOB43_001759"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCI0982615.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            11117..11515
                     /locus_tag="NOB43_001760"
     CDS             11117..11515
                     /locus_tag="NOB43_001760"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCI0982616.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            11581..12663
                     /locus_tag="NOB43_001761"
     CDS             11581..12663
                     /locus_tag="NOB43_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0982617.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            12875..14437
                     /locus_tag="NOB43_001762"
     CDS             12875..14437
                     /locus_tag="NOB43_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982618.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            14430..15563
                     /locus_tag="NOB43_001763"
     CDS             14430..15563
                     /locus_tag="NOB43_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982619.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            15563..16519
                     /locus_tag="NOB43_001764"
     CDS             15563..16519
                     /locus_tag="NOB43_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982620.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            16618..17784
                     /gene="deoB"
                     /locus_tag="NOB43_001765"
     CDS             16618..17784
                     /gene="deoB"
                     /locus_tag="NOB43_001765"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCI0982621.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            17808..18626
                     /locus_tag="NOB43_001766"
     CDS             17808..18626
                     /locus_tag="NOB43_001766"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0982622.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            18643..19350
                     /gene="deoD"
                     /locus_tag="NOB43_001767"
     CDS             18643..19350
                     /gene="deoD"
                     /locus_tag="NOB43_001767"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0982623.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="NOB43_001768"
     CDS             complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="NOB43_001768"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI0982624.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(20506..21087)
                     /locus_tag="NOB43_001769"
     CDS             complement(20506..21087)
                     /locus_tag="NOB43_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0982625.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="NOB43_001770"
     CDS             complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="NOB43_001770"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCI0982626.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            22222..22635
                     /gene="rpsL"
                     /locus_tag="NOB43_001771"
     CDS             22222..22635
                     /gene="rpsL"
                     /locus_tag="NOB43_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCI0982627.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            22719..23189
                     /gene="rpsG"
                     /locus_tag="NOB43_001772"
     CDS             22719..23189
                     /gene="rpsG"
                     /locus_tag="NOB43_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCI0982628.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            23283..25370
                     /gene="fusA"
                     /locus_tag="NOB43_001773"
     CDS             23283..25370
                     /gene="fusA"
                     /locus_tag="NOB43_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0982629.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            25542..26729
                     /gene="tuf"
                     /locus_tag="NOB43_001774"
     CDS             25542..26729
                     /gene="tuf"
                     /locus_tag="NOB43_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI0982630.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
BASE COUNT         8464 a         4955 c         5695 g         7759 t
ORIGIN      
        1 ggtttatact atagccctgt tagtactcca gcagattttc ggatgcttac tcctattgta
       61 ctggagcaag cctttagaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 gtttatgcac cacaggaata tctttcacgg gcatataacg atgctcccaa atattgtgca
      181 aatatcgtaa atactcaact gaaaaataat gaggtcatta ttattggaga aattcctgct
      241 cgatgtattc aagattatcg caatgattta acttttttta caaatgggct tagtgtttgt
      301 ttagcagagc taaaaggata tcaggttacc actggcgaac ctgtttgcca gacccgtcgt
      361 ctaaatagtc ggatagataa agtaagatat atgttcaata aaataactta gtgcgtttta
      421 tgttgttata taaatatggt ttcttattaa ataagatgaa atattcttta atatagattt
      481 gaattaaagt ggaaaggagg agattgttat tataaactac aagtggatat tgtgtcctat
      541 ttgtggaaat aaaacaagac tacgaatacg agtggatact atacttaaaa atttcccttt
      601 atactgcccc aaatgtaaga acgaaacttt aattaatgtt caaaaaatga atataataac
      661 aatcaaagag ccagacgcca agacgcagag ccgataattt gagaaatgaa actctcatct
      721 tatcggctct ttttgtttat ctgaatttta ctgactagcc ttcaatattt cttgcttcat
      781 tgataccttt tgctagtgct tccattaagg atagttcttt gtctgtaaag ctatccatgt
      841 atttttctac ctgtaacctt cgagtgcttt taatcaaatt atctgtaggt aagaaaaatt
      901 catcaataga tacatggagt aatgatacaa gatcatacag cacttgtgta cttgggtgtt
      961 gtcctttgtt ttctatattt gttaaataac gtgggtcaat ttcaatcatt gttcccactt
     1021 gttcacgagt gagaccccgt ttcattcgag cctctttaat cgctaaacca acggctctaa
     1081 aatcgtattt atcttctttt ttacgcatac taaatcacct ctatacattt tactgttcct
     1141 atataaccat aaacaggtat agaaaaacat gttatatagt ttatgagttc ctatagaaca
     1201 ctgtggaatt tattaatgcg atgaatccaa tttcaaatag aaaggtcgct gattttattt
     1261 acctatacaa ctttataaaa tttagtcata ctcctagaaa gtagataaaa ttggcgactt
     1321 aatggaggga aaagtcgcca tgagaaagat aatctgtcat ctagttctct taattaagtt
     1381 cttatcaaaa aaacttatcc acctgtactg gatagatatg accatcaatg tggttttgca
     1441 gattacatag atagaaaaat caaagcatat gaacagagaa aacaatctgt ttatgtgctt
     1501 ttttggtcac ttaataaata tcttttagga tttctcttca tttatgcaac aaatcccccg
     1561 ttcgtgtcgg ggtttagtat gaagggagat aaagaagcac atgccactcc ctttcacgac
     1621 agaaaggggg tgaaaagcat gaaaccatct tcttttcaag aaaccataga aaatcagttt
     1681 gactatatct gcaaacaagt tattgaagat gaacgaaaag attacttcaa acatctagac
     1741 agactatcag caaaagaagt ctcgttttct gatatagata actaccttgt caactctttt
     1801 tctactgttg atacgtacgt cactgatttc caactattta aattatttgg attaagaatc
     1861 aatgttgaaa gtgatttatt aagtgaagcc ctgcgtcatc tttcagagaa aaaacggaac
     1921 attattttac ttcattactt tatggatatg agtgatgtgg agattgcgga gttactaaat
     1981 ttgaatcgtt cgactgttta tcgtcatcga ataagtggac tagccatgat taaagaattc
     2041 atgaaggagt gtaaagaatg aaaacagctt atccaagggt tcccttcccc ctcattgtaa
     2101 aggcgacaga tggcgacgtg gaagcaatta atcagattgt taaacattat cgagggtata
     2161 cctcaaaacg ttcattacgt cgcatgacag acgaatatgg aaattctcat atggttattg
     2221 atgaaaccct acgtggcaga atggaaacga aactcatctc taagatttta tcgttcgaaa
     2281 ttaaatagtc ccattttttc gtggaagcgt gtcgaatcgt atccacgctt cccgatttgg
     2341 gaggtttgtt attccatcaa agcatattgt gtgttcagta ggttttgata ggctaacaag
     2401 ccaaacgttc tttgacaacc aaataaaggc aatcgaatac gtttcggtaa gaaaagagct
     2461 gatgaactaa cacgccatga cctacaaaat tagtgagcga ttcatgttag taattcgaaa
     2521 gtaatcttta gcaggattgc tgccatgact ttcttatcgt gataatgata ctcccgtata
     2581 gccatagtcc gagcgttaga agcgtcacag gcaatgggta cggctacatg agaaccatgc
     2641 agaagtgaaa ttcctgtgag ctttgctaga gctgttcgat tgctaagata ttcttctctt
     2701 gtcagtgtat tattataaaa ctatttgata taattatagg tgaatattgg agttttccta
     2761 gcctataatt gggaaaggag taataatgat aacggtcaca aaaaaggatt tagttgagct
     2821 aggatatgga acttcttttt cagcagacat cataaaaaaa gcaaaagaat tgatgattac
     2881 aaaagggcat atctactatc aatctcgaaa gctagataga gtccctcgtg aagctgttga
     2941 agaaattcta ggaattcggt tttcaaatga aaacaggtct gagtagtttt tgcacagtaa
     3001 ggagtaaaaa ctatggttaa agacccaata aaaaaagcaa agaatggaac ctattatttt
     3061 cgtgcaaatc taggttatga ttctaaaggg aaaaaaattc aaaaatatcg tagtggattc
     3121 actactaaaa aagaagcaag agaagaatat tcgaaactgc tattgatgaa accagaagaa
     3181 ttaagtgaga ataaggataa aatgacgttt aaacattata tctttgaaat tttccttcca
     3241 tggtataaga cacaggtaaa gctcagaaca tatgaaaatc gcttaccaac tattaagaag
     3301 catttctctt attttgataa aatggctgtt tccgatattg agcctattga tgtgcaaaat
     3361 tggcaactaa aattatcaaa gaagtgtaag tcttcttatg taagagctgt tcaaggacta
     3421 ttttcagttg ctatggatcg agcaattgtc cttgggataa ccaccacaaa tccatctaag
     3481 attattggca atgtgaaaaa gcaaaagtct aaaattgaat tttggacaaa agaagaattt
     3541 gaaaaagtaa tctctctaat ttacaaagaa gattactatc aacacttttt atttatctct
     3601 ctgtggtttt tatttatgac tggaatgcga attggtgaag ctactgccat tcaatgggaa
     3661 gatattgatt ttgactcagg agtactaacc atcaacaaaa cactctatta caagaatcaa
     3721 tcgaattata gatttgttga accaaaaaca aaggcgagcg ttcgtcatat tgtattagat
     3781 aaatgcacat taacttattt atccgaatgg aaggaagtac aacaaaatct aattcagaca
     3841 gactttgtaa tgagctataa cggtattcct acccaaaaac atacactatc atatgctatt
     3901 gaacgctatg ctaagctggc tggtatccat cgaatcagaa tccatgggtt acggcattct
     3961 catgcttcct tgttaatcag tatgggagaa aatccactta tcattaaaga tcgtctagga
     4021 cacgaagata ttgagacgac tttaggaacg tatggacatc tttatcctaa cagtaatttc
     4081 gaggtagcta acaaattaaa tggagccatt tcctttaaag aagcaaaaca aaattatgat
     4141 acttcaccaa agaatcaatt tactgtagac tacttgcgaa acaaagaaat gaaaaaagtg
     4201 caataaaagt gcagtaaaaa gataagaaga gccagaaacc cttggtataa gaggatttct
     4261 agctctccta caactattcc cactccactg ttgctggtgg tttagaagtg atgtcataca
     4321 cgatacggtt gacgtgggct acttcgttta cgatacgtac agagattttt tgcaagactt
     4381 cccatgggat acgggcaaag tcagcggtca ttccgtcgat tgaagttaca gcacggatac
     4441 cgactgtgta gtcgtaagta cgtccgtcac ccataacacc gacagagcgg atccctggaa
     4501 gaacagtgaa atattgccag atatcacggt caagtccagc agctgcgatt tcttcacgca
     4561 agatagcatc agattcgcgt acgatttcta gcttgtcttc agtgatttcg ccaagaacac
     4621 gaataccaag accaggacca gggaatggct gacgccaaac gattgaatca ggcatgccta
     4681 actgagtccc taattcacgg acttcgtctt tgaataatgt gtttaatggt tcgatcaatt
     4741 caaattgcat atcttctggc agtccaccta cattatggtg agatttgatc gtctgtgctg
     4801 tttctgtacc agattcgata acgtcagtat acaacgttcc ttgtgctagg aaagagacgc
     4861 cttcttcacc agcaagtttt gttgcttcgt catcaaaaac atatacgaat tcattcccaa
     4921 tgattttacg tttttgttct gggtcagata cacctttcaa cttgtctaag aagcgatctc
     4981 ttgcatcgac tttgatgatg ttcaagccga attttccgcc tagactttcc attacttgtt
     5041 ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat agatgtcaat tggtcaccga
     5101 tcgctttttg taaaagaacc ccaacgacac tagaatcaac gccacctgaa agaccaagca
     5161 agactttttt gtcaccaact tgttcacgga ttttttctac ttgcatatcg ataaagttat
     5221 ccattgtcca gttaccttca cagtgacaaa catcaaaggc aaagtggcgc agcaattcga
     5281 ttccgtattc ggaatgacgt acttctgcat ggaattggat accataaaaa ttacgtgttg
     5341 tgtcttggat agaagcaatc ggacaatctt tgcttgttcc gactgtttca aagccttcag
     5401 gaactttagt taccaagtca ccatggctca tccatactgt ttgttgtttt ggtgtttctt
     5461 taaacaagac agcttgatcg cttgttactt ctaacaaggc tttcccatat tcgcggtttt
     5521 tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc
     5581 ctaatacagg aatacctaaa ttgaagatct caggatcgat cccaaatgca ttctcatcat
     5641 atacactgtt tggtccgcca gaaagaatga ttccctttgg attcatcgct tttacttctt
     5701 ctgcagtaat gcggtggctc aataattcgg aaaagactcc aagatcacga atacgtcttg
     5761 tgatcaattg gttatactga ctaccgtagt ctaatacgat aatcttttca acgttcgtca
     5821 tatcggcaac gtttgtcaaa tttattaccc ctatcccttt aaattttatc tcaaaatagt
     5881 caaactattt taaaatgcta atattttcgc atgaaaatcg aatcgatgat atgattttca
     5941 gttttatgga gaattatatc ggctcttcct cgtgtaggca agatatattc ctgtaaattt
     6001 ttcaaattca catttttcca tacatctttt gccattttaa aggcttcttc acgatctccg
     6061 atagcaaaac gataataata attctctgga ttttggaaag ccgtatccag taacgcacca
     6121 aaacgatcca aataccattt ttcgatcagc acgggatcgg catcgacata gacagaaaaa
     6181 tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta attgaagcgt attgatcccc
     6241 tcaacgatca agatatcagg ctgctggatc aattcgtact tgtctggaat gatatcatac
     6301 acatcatgtg agtaaacagg tacttttatc tcttcctgac cagattttac acggttcaag
     6361 aaatcgatca gcatctccat atcataactt tcaggaaatc ctttacggtc catgattcca
     6421 cgctctttta atatacgatt tggataaaga aatccgtcag tcgtgatcag ctgaacgttt
     6481 cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc tggctgttgt actttttcca
     6541 acggctacac ttccggcgat cccgataata aaaggcggta cttctacgta tttatgaaga
     6601 aataaacctt tactcaagaa caaagattca aattctttca tataaagata aatcagatga
     6661 gcaagaggta catagatatc tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg
     6721 atattatcta gttcatcttg tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat
     6781 tcttctcttg ccacacggta gtagttcatt ggatcattca tattagcctc ctgcgttctc
     6841 ccatcaatgg aactatttta acacaaaata aacgcaaacc ccaccactta agagagattg
     6901 ccgatctttt tgtataatct ttataataga aagaaacgga gtcttattct tgacttgcgc
     6961 acggatacat aaaaggatag actgttgtca tgaaagaaat gagaaggatg gaagacatga
     7021 caaatcatta ctattctgaa cgcccagata cggcgcacga ttttgaacaa tgggcttttg
     7081 agttaaaagg cagaaccttt caatttgtaa cagattctgg tgtattttca cgtgaaacag
     7141 tggattatgg ttcacgtgtc ctgattgatg ctttcgattg ggaagagtta cctgatgaag
     7201 gaaagatctt agatgtggga tgcgggtatg gaccgattgg gttagctttg gcatttgcga
     7261 cacagcggtt tgttgaaatg gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa
     7321 acgcaaagcg taaccaaatc gaacatgttg atatccatca atcgaatatc tatgaagcag
     7381 ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag
     7441 ttgtacatga aattttgaca ggcgcatatc ctcggttgaa gaagggcggt acactgacaa
     7501 ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg
     7561 gtaatgcaga aatcgtcaca aaagataaag gatattatat catcaaaagt gtgaaagaat
     7621 aactagctga aaaatagtgg agcgacgaaa gagtggaact gggcgtgcat gtacgggtac
     7681 gtatcagttc tttttttgtt gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa
     7741 agaaatagta ggaacagagt cgttgttttt tacgataaaa taaataagat acagaacttg
     7801 tatagaaggc tgccaagtcg gtagataaag gaggttttta tcaaaaaaca tactttcctt
     7861 ttttctctat tcttttcttg ggggttttgg tacactgata gggaatttag atagaaggga
     7921 gccaatagga tgaagctgac catcagagat atcgcagaaa tggcaggcgt atcagtaaca
     7981 actgtctcac agattttgaa taacaaagga agcagattta gtgataagac aagaaaaaaa
     8041 gtgttgtcga tcgtgaatga acatcattat aagcccgatt atttcgcttc aaatgtgatc
     8101 aatcgacatt caaagaccat cggaatgatc gtccctgatg tcactgattt cttcttctcc
     8161 aaactgatcg aaggtgtaga gagctatttg aatcctttgg gctatgtgat catgttatgc
     8221 aattctcgtc atagccaaga aaatgagatc aagtatttac aagagctttc ccaccgctca
     8281 gtggacggaa tcttgctggc cacaccaaat attttacctg agaaatatgc attagacagc
     8341 ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg gattgaatcg tcgggataac
     8401 ggacggctta tcgtaaagga atatgagggc gcctatcaag ctgtttcgct gtttattgaa
     8461 aatggccata cgaagatcgg catgctgaag gaaaccactg gatactatca attagaagaa
     8521 cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt
     8581 gttgaacatg gagagttgac tgtccaaggt ggatatactg catcaaaaaa attactcaaa
     8641 cataaagata tcacggctat tttttgcggg aatgatgcca tggcgatcgg atgctatcag
     8701 gcgatcgatg aattgggcaa aaaaatccca gaagatatct cagtcatagg attcgatgga
     8761 ttaaagctgt cagaatacat gattccgcaa ttgacgacag tgcagcagcc aagttttgat
     8821 attggatttt atgctgcacg tttcctgatc gatacgatcg aatttcctca aagaaaagtt
     8881 ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga gcgtaaaagt attgacaaag
     8941 ggctaactcg gcggtatatt gcttatgtaa gcatttacaa aggctagtta gtgctttttt
     9001 tatttttagt aaaccagttt actaaagtgg tttacctttc ctaaaaataa tgtataatac
     9061 cgaatgaaga caaggaggat caggcaatgc gaatggtgga tctgattgaa aaaaagaggg
     9121 atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt cacgaactat acgaatggaa
     9181 agattccaga ttatcaagtc agtgcattat tgatggcaat tttttatcaa gacatgacaa
     9241 atgaagaaat cacgaactta acattggcga ttgctaattc tggtgatgtc atcgatttga
     9301 gttctcttga aggaataaag gtagataagc attcgacagg tggcgttggt gacacgacca
     9361 cattgatttt agccccccta gtagctagtg tcggagtgac agtggctaaa atgtctggac
     9421 gcggtctagg ttacacaggt ggtacactag acaagctaga agcaattccc ggatttcaga
     9481 tcgagctttc ggatgaagaa tttgtacgca ttgttaatga aagtaaagta gcggtaattg
     9541 gtcaatcagg aaacttggca ccggcggaca aaaaattgta tgccttgcgt gacgtcacag
     9601 cgaccgttga ttctcttccg ctgattgcca gttcgattat gagtaaaaaa atcgcggcag
     9661 gagcagatgc aatcgttttg gatgtgacca ctggagacgg tgctttcatg aagaacatcg
     9721 aagatgcaag acgtctggca aagaccatga cgagcattgg gaaactggct aaccgagaaa
     9781 cagtggcggt tatctcagat atgtcagaac ctcttggcga agctatcgga aatagtctag
     9841 aagttgtcga ggcaatcgaa acattacaag gaaatggtcc agaagatcta gtagaaatgt
     9901 gctacgcctt aggaagccaa atggttgttc ttgctggcaa agctaagaca accgatgaag
     9961 caagaacgtt gcttcaagaa gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa
    10021 tgatccaaaa tcaaggggga gacccagcga tcgtggaaca tccagaacga attttgactg
    10081 cacgctacac aatggagctt cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa
    10141 atgaattagg aattgctgca atgatgctag gtgctgggcg taaaaccaaa gaagaagata
    10201 ttgatcacgc tgttggattg aaactgcata aaaaaattgg tgacactgtg acaaaaggtg
    10261 agtcactatt gacgatctat agtaacgacg aagaaatcac ttctgtcatt gaattattat
    10321 ataaaaatat tgaaattggt gaatcggcaa tgaagccaac gttgattcat gacatcatca
    10381 cagaataaag gaaaaaagcg gactttaccg ttttaaagaa aaggggaaaa gaaatggaac
    10441 taaaccgaat gatcgaccat actattttga aagcagacgc atctaaagaa gctgtgatgc
    10501 aaattatcga agaagcaaaa aaataccatt tttattctgt ctgcatcaat ccagcatggg
    10561 ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt
    10621 ttcctctagg agcaaacaca cccgagacaa aagcatttga aacaacagat gccatcaata
    10681 acggtgcaga tgaagtcgat atggtcatca atatcggtgc tttgaaatca aaggatgatc
    10741 aacaagtcca aaaagatatc gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca
    10801 aagttattat tgaaacatcg ttattagata gagaagaaat catccgagct tgcgaaatag
    10861 caaaagctgc aggcgctgat tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa
    10921 aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt
    10981 ccggcggtat ccataacgaa gaagaagcaa tggcaatgat cgaagctggt gctacaagaa
    11041 tcggaacaag cgcaggagta gcaatcgtat ctggttcaac tggtgaaggc tattaatttt
    11101 ttcaaaggag aagctcatgg cagaactcaa acaagaatgg atcaacacag ctattgaagc
    11161 gttagataaa gcctatgttc cttattccca ttttccggta ggcgcttgtc tcgtaacgga
    11221 atcaggcaag atttatcaag gcatcaacat tgagaatgca tcatttggat taacgaattg
    11281 tgccgagcgc acagcttttt tcaaagcagt atctgaagga gaaaaaacat ttacgcatct
    11341 agtcgtagcg gggcacaccc ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat
    11401 ggcagaattc tgttcccctg atatgccggt tacgctagta ggagacaatg gtgtgacgaa
    11461 ggcaacgacc gttcgtgcac tgctgcctta tgcatttact gaaaaagatc tataactcat
    11521 gttcattcag tcagctgact gttgaaaaat aaaacaatta ttttaggagg ctttacagaa
    11581 atgaaaaaag caaaattatt tggtttaggt gctgtcgcac tagcagcagg gttattttta
    11641 ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg gcaaaagctc atcagacaca
    11701 acaactgcag cattgatcac agacacaggt ggtgtagacg accgttcatt caaccagtca
    11761 gcttgggaag gactagaaaa atgggggaaa gatcaaggac tttcacgagg aaatgatggc
    11821 ttccaatatt tccaatcttc aaatgaatca gattacatcc caaatattga ccaagcattg
    11881 aatgctggat tcaaaacgat ttttggtatt ggttataaac taaaaccagc gatccaagaa
    11941 caagcaacaa acaatacagg tacgaacttt gttattatcg atgatgtcat cgatggatta
    12001 gataacgttg tatctgcaac tttcaaagac aacgaagctt cttatcttgc aggtgttgca
    12061 gcagcttata cgactgaaac aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta
    12121 atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg caggtgcgaa agaattagga
    12181 aaagaaatca aagtattgaa tcaatatgct ggtgacttct ctgctccaga taaaggacgt
    12241 tcaattgctc aaggtatgta tgcacaaaac gcagatatca tcttccatgc ttcaggcggt
    12301 acaggtaacg gtgtattcca agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt
    12361 tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg aatacacatt aaacggcgaa
    12421 aagaaaaact tcacattgac atctacactg aaagcagttg gaacagtagt agaagatttg
    12481 gcacaaaaat cagcggacgg taaattccct ggcggcgaac acactgttta tggattgaaa
    12541 gaagacggtg ttggtctaac agaaggacaa ctttctgacg aagcgaaaaa agcagttgat
    12601 gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac
    12661 taaaaccatt tctatagcct tgttagacac atgtttgaca aggctatggt ttgattagaa
    12721 caagaattgt tcatttatcc aagctgcctt gtgacagttt ggataaggga acaactccct
    12781 gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg tgaatcttag tcaatcgttg
    12841 ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga
    12901 aatgcagaat attaccaaag aatttggaac attcaaggca aatgacaaca tcaatttaca
    12961 agtaaaggca ggagaaattc atgcgttgct tggagaaaac ggtgctggca aatctacatt
    13021 gatgaacgtg ctttccggat tattagagcc gacatcaggg aaaattttga tgcgtgggaa
    13081 agaagtaaag atcacaagtc cgaccaaagc caaccaatta gggattggga tggtccatca
    13141 gcactttatg cttgttgatg cctttactgt aacagaaaac atcgtgttgg gaagcgagcc
    13201 tagtcgcgca gggatgcttg accataaaaa agcacgaaaa gagatccaaa aagtttctga
    13261 acagtatgga ttgtcagtca acccagatgc ttacgttcgt gatatttcag ttggaatgga
    13321 acaacgggta gaaattttaa aaacacttta ccgaggagca gatgtactga tttttgatga
    13381 gccgacagct gtattgaccc ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt
    13441 agtcaaagaa ggcaagtcga tcattttgat tacgcataag ttagatgaaa tcaaagcagt
    13501 agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga
    13561 cgtaacctca caacaattag ccgatatgat ggttggaaga acggtttcat tcaaaacgat
    13621 gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga
    13681 aaatcgtgga ttagaagccg tgaaaaactt gaacttagag gttcgtgctg gcgaagtact
    13741 tggtatcgct ggaatcgatg gaaacgggca gtcggagttg atccaagctt tgactggttt
    13801 gcgaaaggca gaaagcggac atatcaagct aaaaggggaa gacatcacta ataaaaaacc
    13861 ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt
    13921 agtcctagat atgacattat ctgaaaatat cgcactacaa acctatcatc aaaaacctta
    13981 cagtaaaaac ggcatgctga attattcagt aatgaatgaa catgccagag aattgatcga
    14041 agaatatgat gttcgaacaa cgaatgaact tgttcccgca aaagctttat caggcggaaa
    14101 tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc
    14161 aaatccaact cgtggactgg atgtaggtgc gatcgaattt attcataaac gtctgatcga
    14221 acaaagggac aaatacaaag cagtgttact gatcagtttc gaattagaag aaattttaaa
    14281 tgtttcggat cgtattgctg ttatccatga aggagaaatt gtcggtatcg ttgatccgaa
    14341 agaaacatct gaaaatgaat taggtctatt gatggcgggc tataccttag aagaagcacg
    14401 aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt
    14461 tattagtgcc tgtactttca gttgttttag gattgatctt aggcgcgata ttgatggctg
    14521 cttttggttt tcagcccatc caaggttatt cttctatgct agatgcagcc cttggttcgc
    14581 aaagagggat aggtgaaacg ttaaggcaag caacgccgtt gatttttaca gcattaggtt
    14641 tttctgtagc taactcagct gggtttttca atattgggct ttctggacaa gcactttgcg
    14701 ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga tctgccaaaa gttgttttgc
    14761 ttccgttatg cgtgatctta ggtgccttag ctggtgcgat ggcagcggct gttccaggtt
    14821 tacttcgagc attttttgga acaagtgaag tgatcgtaac aatcatgatg aactatatct
    14881 tattatacgt aagcacattt gctttacatg aagtgatgcc tgaaagctat cgctcaagtt
    14941 tggactcttc caatatgatc agtcaaaatg cctcactgcg gttaccatgg ttaacacaag
    15001 cttttggcgg ctctcgcgta aactcaggat tatttttagc aatcatcgcg cttattttcg
    15061 tttggctgct gatgaagaaa acgactttag gatttgaaat ccgttctgtt ggattgaatc
    15121 cttttgcttc tgagtatgca ggaatgagta gtaaacgtac gatcgttttg tcgatggtca
    15181 tttctggcgc tttggcaggg cttggcggtg tggttgaagg attaggaacg tatcaaaact
    15241 tctttgttca aacgacttcg ctatctattg gatttgacgg aatggctgtt tccttgcttg
    15301 gttctggatc agcaatcggt attcttttat cagcgatctt gttcagtatt ttgaagatcg
    15361 gtggacttgg catgcagaca ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg
    15421 ctttgattat cttctttgtc gggatcaact tcctgattcg tttcgtcatg gctaaagtct
    15481 tccaagggaa aaaacaagaa gagatcgttg cgacaataga atcgaaacca acgaatcaaa
    15541 accatgaagg gggcgaacta taatgtcgac tatcgaatta attgccttga tccttacttc
    15601 tacactggtt tattcaacac cgctaattct aacgtcacta ggcggaactt tttctgaacg
    15661 aagcgggatc gtaaacgtag ggctagaggg aatcatggtc atgggtgctt ttagttccat
    15721 cgttttcaac ttgacgatga gtccatcact tggttctatg acaccatgga tcgctatttt
    15781 agtgggtggc gtcgtaggta tcctattttc tctgattcac gcagtagcaa cagtcagttt
    15841 gcgtgctgac catattatca gcgggacagt aattaatctg atggcacctg ctttaggtgt
    15901 tttcttgatc aaagcatggt atggtaaagg tcaaactgat aacatcacgc agaatctggg
    15961 gtatttttct ttcccaggat tagcagatat tccggtcatt ggaccaattt tctttaaaaa
    16021 tacattctta cctgcttatt gtgctatttt gattgctgtc ctagcttggg tgatcatctt
    16081 caagacgaaa ttcggcttgc gcctccgttc agttggtgaa aatcctcaag ctgccgacac
    16141 attaggtatc aatgtatatg ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg
    16201 cggtatgggc ggtgctgttt ttgctcagtc gatttccggt aacttttcag ctggtacgat
    16261 cgttggacaa gggttcatct ccatggctgc tatgatcttt ggtaagtgga atcctttagg
    16321 ggcaatgggt gcctcattgt tctttggttt tgctcaaagc ttgagtatca ttggcgcaca
    16381 attaccagtt atttcttcga ttccgccagt attgctgcaa attgctccat atttgctgac
    16441 aatcattgtg ctggttgttt tcttagggaa agcttctggt ccaaaagcaa acgggaagaa
    16501 ctatatcaaa tcaaaataat cttttagcga ataaaaaggg tgggttacgg gaagtgtttt
    16561 tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa agaaagaagg aataatcatg
    16621 tttaaacgcg tacatctgat cgtcatggat tcagtaggaa ttggagaagc accagatgcc
    16681 gataagttcg gtgatgttgg ttctgataca ttaggacaca ttgcgaaaga agcaggattg
    16741 aacgttccac atttagagca gcttggttta ggaacgatcc gtcctcttga aggtgtggaa
    16801 tcagtgaaag atcatcaagg ctatgcgacg aaattagaag aagtttctgt agggaaagat
    16861 acgatgacag gccactggga aatcatggga ttgaatatca aaactccatt tcgtgtgttt
    16921 cctaatggat tccctgatga tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc
    16981 gtatgtaaca aaccttatag cggaacagct gttattgacg attacggtga acaccaaatg
    17041 aaaacaggcg atttaattgt atatacttct gccgatcctg tccttcagat cgcggcacat
    17101 gaagaaatca ttcctttaga agaattatat cggatttgcc aattcgttcg tgatataaca
    17161 aaagatgatc cgtatatgat tggccgaatc attgcacgtc cgtacgtggg tgaaccagga
    17221 gacttcacac gaacaagcaa tcgccatgat tatgcgttga atccattcgg acacacagtc
    17281 cttgattctt tgaaagaagc aggaaaggac gtgattgctg ttggaaagat caacgatatt
    17341 ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac
    17401 cagctgctga aagttatgaa aaacgatttt tcaggaatca gctttaccaa tttagtagat
    17461 tttgatgcat tatacggtca tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa
    17521 tttgacttac gaattccaga attgcttgaa gcgatggaag aagacgactt gctaatgatt
    17581 acagccgatc acggaaacga tccgacgttt actggtaccg atcatacgcg agaatatgta
    17641 ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg cattgcctca aggatattat
    17701 tcagatattt cagcaacgat tgctgagaac tttagtgttt cttcgactga aaatggcgaa
    17761 agcttcttga aattattaaa ataatctttt taaataggag aaagcaaatg accaagttaa
    17821 gcgagatgtt acaagaaacg acccagttta tccttgataa aggagtaaaa gaaattgatt
    17881 ttggtttgat tctaggttca ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa
    17941 tgatttctta tgatgagatc ccgttctttc ctgtttcgac agtagttggg catgcaggaa
    18001 agctagttta tgggtctctg gcaggcaaga aagtgttagc catgcaaggg agattccact
    18061 actatgaagg tcattccatg caaacagtga cctatccagt acgtgtgatg gccggactag
    18121 gggcccattc agtcattgtg actaatgcat gtggtggtgt caacgaatca tttgtaccag
    18181 gagatttgat gctgattacc gatcatatca attttactgg tgaaaatcct ttgatcggtc
    18241 cgaatgaaga tgcaatgggc cctagatttc cagatatgag tcaagcttat acgcctgact
    18301 atcaagcaac agcaaaagca gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat
    18361 atatgggcta ttctggacca acttatgaaa cgcctgcgga gatccgaatg tctcggacaa
    18421 taggagccga tgcagtaggg atgtcgactg ttccagaagt catcgtagca gctcacagcg
    18481 gattaaaagt gttaggaatc tcttgtatta ccaacttagc agcaggtatg caagcgaatc
    18541 tgagccatga agaagttgta gaaacaactc agagagtcaa acaatctttt aaagcattgg
    18601 ttaaagaaac attgacatta ttgtaatagg aggaacaata aaatgagtgt gcatattgaa
    18661 gcgaaagaag gcgagatcgc cgataagatt ttacttccgg gagatccttt gcgagctaaa
    18721 tatattgcgg agactttttt ggaagatcca gtttgttaca atcaggtacg cggtatgtta
    18781 ggctttaccg gcaaatataa aggagaacgt atttctgttc aaggaacagg aatgggaatg
    18841 ccatcagcca ccatctatgc ccatgaattg atccagtcgt atggtgtaaa gaaattgatt
    18901 cgagtaggta catgcggtgc attgtcaaaa gacgtccatg ttcgtgattt agtactagca
    18961 caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct
    19021 ccaatcagtg atttcaatct attactgaaa gcatatgaga tagctaaaga aaagggctat
    19081 acggttcatg taggaaatgt tctttcggaa gattctttct acaaagatga tttgacagag
    19141 acgttccaat tagctgaact tggcgtttta ggagtggaaa tggaagcagc ggctctttat
    19201 tacttaggcg cgaaatacca tgtgcagaca ttaagtttga tgaccgttag cgaccatttg
    19261 atcaccggtg aagaaacaac agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa
    19321 gtaggattgg aaacagcgat agcagaataa gaaggaaatg aaaaagctgc cctgcattaa
    19381 gtaataagaa catccaagca aaaatagctc ctcatgtttt tgacttggct ggacttatta
    19441 ttgcaaatgt aagcttttga acaccgttta ccaagaggtt gtgaatctgc cgtttaactc
    19501 tgagtcacaa ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg
    19561 tgaccgagaa gttggcagga gaaaaccgtt tatacgaaaa aagggactgt gacaaatcgt
    19621 gtcacagtcc cttttttata gtgtttttta taggtagtat tttttagcaa ctgttaagtc
    19681 atcatttaat tcataaacaa gtggttgacc tgttggaatt tcaagatcca tgatgtcttc
    19741 gtcagagata ccttcgatat gtttagctag ggcgcgtaat gagttaccat gtgcagctac
    19801 taaaacagtt ttgttgtcta gtaatgctgg agcaatttca tcttgccaga atggcaaagc
    19861 gcgttctaat gtcactttca agttttctcc accaggaata tcgcgtttgt ctaacattgc
    19921 gtaacgacgg tcatttgctg cagaaccttc gtcagtttct tccattaatg gaggaagagt
    19981 atcgtaagaa cgacgccaga tgtgcacttg ttcgtcgccg tatttttcag ctgtttcttt
    20041 tttgttcaaa ccttgtaatt taccatagtg acgttcgttt aagcgccatg atttgatttg
    20101 tggtacccaa agttgatctg aatattctaa gatcaagtta catgttttga ttgcacgagt
    20161 taaaacagaa gtgtaagcaa catcaaattc gattccagct tctttgattt tgcgtccgcc
    20221 ttcttttgct tcttcgattc cttctggtgc tagatttaca tcagcccaac cagtaaattg
    20281 gttcaatgca ttccattcac taagaccgtg acgagaaaaa actaattttg gcatgtttag
    20341 ctctcctttt aagataggtt tatatttctg aaattttcag ttctgtttta ttgtacaatt
    20401 ttttggaaga gatttccatc gaaaaattag ataagattct atgagaaaac aagtagagaa
    20461 tataaaaaaa cgaacagtgc ccacgcaact gttcgttttt aggtattaga tgcataattg
    20521 ctcgatttct ttttcaggta aattgatata tttataacat gttccaactg aaacaccgca
    20581 ttttgaagaa ataaattgga tcgtttcttt tttttcataa tagagacgtc ggattttttt
    20641 gatcgttttt gcatcgattt ttggtcttcc gccgattttt ccttttttac gagcttcatc
    20701 taatccaact aatgtacgtt ctttgatcaa tgcgcactcc atgtttgcta ggttttccat
    20761 taattggaaa tagatttttc ccatttcgcg cgtatcgatt ccttcatcaa gactaatcaa
    20821 gtgcagcccg cgatctttga ataattgcgt gagttctgtt aattgccgcg tagatttgcc
    20881 taatcgatga agttggcaaa tgactagtgc atcgccttgt tgcatgtcag cgatcactga
    20941 ctccaaatga acagcagtag aatcattttg ttccacttca tatgtctcat ggaaaatttc
    21001 ttgacaacca aagtcagata attgatcaac ctgagttgtt aaatcaacgt catttatggt
    21061 tgtgcgtgca taaccaataa ttttcatggt gattcctttc tagcagtgat tttctaactg
    21121 gatataacag taaaaatgta gcataaagta cgtcaaaaag atagtttttt cgcaaatttt
    21181 ccgctgtctt tttttattgg atgatcaagc agtttttctt tatttacgac ggattgcgtc
    21241 aagaatctca acgccttttt ctgagccgac aactacttta gaaaccatgt ttaggaaaag
    21301 cccatgttct actaccccaa caagttcatc taaataggta gctaagcttt ctggctgttc
    21361 gatgacttct agatgcagat caatgatgta atgaccacca tctgtggtta agacttctcc
    21421 gttttcgtct gtacgcaaga cgggttggaa tcttttttct tcaaaaatat gaagtagctg
    21481 ttgggagcca taagggatca cttcaactgg gagtgggaac ttcccaagtt tatcgactaa
    21541 tttagaagaa tcaacgatcc aaatcgtttc ttttgagtac gtagcgacta ttttctcgaa
    21601 aagcaaagca gcgccgccgc ctttgatccc ttgaaaatca gcactgattt catcagcacc
    21661 gtctattgtc aaatcgacta cggggacttc atcaatactc tttaacggta ttcctaattt
    21721 ttccgcttgt tcttttgtcg catttgaagt agtaactcct gtgatacgta aaccttcttc
    21781 acgcatacgg cgaccaatct cttctaccat ataataggcg gttgaaccgg tcccgagacc
    21841 tacgatcatc ccgtccttta cgaatttcgc ggcttcaatg ccagctaatt gttttaaatt
    21901 catctttgcg tccacctttt tttagtttga gcatcgtgct ttcctcacta ttttagcgtg
    21961 atttacggta aaaagatacc attctttttt attccaataa agctttttca aaaaaaattg
    22021 catctcttgt tgacatgttt tttcattcgt gatattctaa caaaggtgct ttatctacag
    22081 gtttctgtga agaaacgtgc tgactgttta tcaaagcata tttgataagg atgcagacat
    22141 tgcatttatt ttttatcaca aaaaaagaac cacctggatg tgtggaacta gacgcaaatc
    22201 gtgggaagga ggaaacaagg aatgcctaca attaaccaat tagtacgtaa acctcgtaaa
    22261 tcaaaggtgg aaaaatctaa ttcacctgct ttgaacaaag gatataacag ctttaagaaa
    22321 actcaaacta acgtaaactc acctcaaaaa cgtggggtag caactcgtgt gggtacaatg
    22381 acacctaaaa aaccgaactc agctttacgt aaatatgcac gtgttcgttt gtcaaactta
    22441 attgaagtta ctgcttatat cccagggatt ggtcataact tacaagaaca cagtgttgta
    22501 ttattacgcg gtggtcgtgt aaaagactta ccaggggtac gttaccatat cgttcgcggt
    22561 gctttagata ctgctggtgt taacgaccgt aaacaaagcc gttctaaata cggaactaaa
    22621 aaacctaaag cttaatttta attattaaac aaatgaaact tgcttctact atatagaagt
    22681 aattactatg aacaatattt cggaaggagg agttacggat gccacgtaaa ggtcctgttg
    22741 caaaacgtga tgttttacca gatcctattt ataactcaaa attagtaact cgcttgatca
    22801 accgtgtaat ggttgacgga aaacgcggga ttgcagctaa cattatctat aatgcctttg
    22861 acttgatcaa agaatctaca ggtaacgatc cattagaagt gtttgaacaa gcaatgaaaa
    22921 acgttcaacc tgttcttgaa gttaaagcac gtcgtgttgg gggttcaaac taccaagtac
    22981 cagttgaagt tcgccctgaa cgccgcgtta ctctaggtct tcgttgggta gtaaactacg
    23041 ctcgcttgcg cggtgaacac acaatggaag aacgcttagc aaaagaaatc atggatgctg
    23101 caaacaacac aggtgcttct gttaaaaaac gtgaagacac tcataaaatg gctgatgcca
    23161 accgtgcgtt tgctcactat cgctggtaag attctctctg tttggtcggc ttttataagt
    23221 cgacctcaga tagtgtcctt atttttagca actagatagt aaagagagga gaaacaagga
    23281 gaatgaccag agaattttct ttacaaaaca ctcgtaatat cggtatcatg gcccacatcg
    23341 atgctggtaa aacgactgct actgaacgta tcttatacta tactggtaaa atccataaaa
    23401 ttggtgaaac tcatgaagga gcttcacaaa tggactggat ggaacaagaa caagaacgtg
    23461 gtattacgat cacttctgct gctactacag cacaatggaa gggtcaccga atcaacatca
    23521 tcgacacacc aggacacgta gacttcacag ttgaagttga acgttcattg cgtgtacttg
    23581 atggtgctgt aactgttctt gatgcacaat caggtgttga acctcaaact gaaacagttt
    23641 ggcgtcaagc aacaacttat ggtgtacctc gtatcgtatt tgcaaacaaa atggacaaga
    23701 tcggtgctga cttcttatat tcagtatcaa ctttacatga ccgtttgcaa gcaaacgctc
    23761 acccaatcca attaccaatt ggtgcggaag acgacttcac aggaattatc gaccttgtaa
    23821 caatgaaggc tgaaatgtat acaaacgatc ttggaacaga gatcgaagaa acagaaattc
    23881 ctgaagaata ccgcgaatta gctgaagaat ggcgcgaaaa attggttgaa gctgtagctg
    23941 aaactgatga agaacttact ttgaaatact tagaaggtga agaaatcact gaagctgagt
    24001 taaaagaagg tatccgccgc gcaacagtta acgtagaatt ctacccagta ctatgtggtt
    24061 cagcatttaa gaacaaaggg gttcaattac tattggacgc tgttcttgat tacttgccat
    24121 caccgttaga tatcccagct atcaaaggga ttgaccctaa aactgatgaa gaagtagaac
    24181 gtcctgcaga cgacagcgct cctttctcag ctttagcatt taaagttatg actgacccat
    24241 tcgtaggtcg tttaactttc ttccgtgtgt actctggtgt tttacaatca ggttcatacg
    24301 tacaaaacgc aacaaaaggc aaacgtgaac gtgttggtcg tatcctacag atgcatgcca
    24361 actctcgttc agaaatctct gaagtttacg ctggagatat cgctgctgct gttggtttga
    24421 aagacacaac tactggggac acactatgtg atgaaaagag tctagttatt cttgaatcca
    24481 tggaattccc agaaccagtt atccaagtcg ctattgaacc taaatcaaaa gctgaccaag
    24541 ataaaatggg tgtggcttta caaaaactat ctgaagaaga tcctactttc cgtgctgaaa
    24601 caaatgtgga aacaggcgaa acaatcatcg ctggtatggg tgaacttcac ttagatatca
    24661 tcgttgaccg tatgcgtcgt gaattcaaag ttgaagctaa cgtaggtgcg cctcaagtat
    24721 cttaccgtga aactttccgt gctggcactc aagccgaagg taagtttgta cgtcagtctg
    24781 gtggtaaagg tcaatacggt cacgtatgga ttgaatttac accaaatgaa gaaggtgctg
    24841 gtttcgaatt tgaaaatgcg atcgtcggtg gggttgttcc tcgtgaatac attccagctg
    24901 ttgaaactgg tttgaaagat gctatggaaa atggtgtctt agctggctat ccattagtag
    24961 atatcaaagc taaactttac gatggttcat accatgatgt cgattcaaat gaaactgcct
    25021 tccgtgttgc tgcttctatg gcattacgtg cagcagctaa gaaagctaat ccagtaatcc
    25081 ttgaaccaat catggctgta gaagttgtta tccctgaaga ttatttaggt gatgttatgg
    25141 gtcacgtaac tgctcgtcgt ggacgtgttg aaggtatgga agctcgcgct ggcggccaac
    25201 aagttgttcg tgcgatggtt ccacttgctg aaatgtttgg ttatgctaca actcttcgtt
    25261 ctgctactca aggtcgtggt acatttacaa tgacatttga ccactacgaa gatgtaccaa
    25321 aatcagtaca agaagaaatc attaagaaaa acggcggaaa agctgaataa tttcttaaaa
    25381 ccggatagtc ctgcaaagag attatccaaa gagactatat ttttaatata gtttcgtgta
    25441 aaataattat cgatgatatg ggcatgtggt gtaccttgtg tacatcatat acctatcaga
    25501 caaataaaaa atatattgta tttttaggag gacattttaa aatggcaaaa gaaaaatttg
    25561 accgttctaa accacacgtt aacattggta ctatcggaca cgttgaccat ggtaaaacta
    25621 cattaacagc tgcaatcaca actgtactat ctaagaaaaa cggcggccaa gctatggctt
    25681 acgatcaaat cgatggtgct ccagaagaac gcgaacgcgg aatcacaatc tcaacagctc
    25741 acgttgagta tgaaacagat acacgccact acgctcacgt tgactgccca ggacacgcgg
    25801 attacgttaa aaacatgatc actggtgctg ctcaaatgga cggagctatc ttggtagttt
    25861 ctgctgctga cggcccaatg cctcaaactc gtgaacacat cctattgtct cgtcaagttg
    25921 gtgttcctta catcgttgta ttcttgaaca aagtagacat ggttgatgac gaagaattac
    25981 tagaattagt tgaaatggaa gttcgtgacc tattaacaga atacgaattc cctggtgacg
    26041 atgttcctgt agttgctgga tcagctttga aagctctaga aggcgacgct tcatacgaag
    26101 aaaaaattct tgaattaatg gctgcagttg acgaatacat cccaactcca gaacgtgaca
    26161 acgacaaacc attcatgatg ccagttgaag acgtgttctc aattactgga cgtggtactg
    26221 ttgctacagg tcgtgttgaa cgtggacaag ttcgcgttgg tgacgaagtt gaagttgttg
    26281 gtattgctga agaaacttca aaaacaacag ttactggtgt tgaaatgttc cgtaaattgt
    26341 tagactacgc tgaagctgga gacaacattg gtgctttact acgtggtgtt gcacgtgaag
    26401 acatccaacg tggacaagtt ttagctaaac caggtacaat cacacctcat acaaaattct
    26461 ctgcagaagt atacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcacta
    26521 actaccgtcc acaattctac ttccgtacaa ctgacgtaac aggtgttgtt gaattaccag
    26581 aaggaactga aatggttatg cctggcgaca acgtaacaat ggaagttgaa ttaatccacc
    26641 caatcgctat cgaaaacggt actaaattct caatccgtga aggcggacgt acagttggtg
    26701 ccggtgtcgt tacagaaatc aaagcttaat tcacttaagt tttaaagtaa agcaacattt
    26761 attcggacgt aatcgctcgg aacgaaggtc ttaggatctt tgttccgagc ttttttattt
    26821 attgcaggat caggaaaaaa gacaggagta ttataaatag aagaaacacg aaa
//
LOCUS       DAIGTA010000040        26598 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.040, whole genome shotgun sequence.
ACCESSION   DAIGTA010000040 DAIGTA010000000
VERSION     DAIGTA010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.040"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            99..542
                     /locus_tag="NOB43_001775"
     CDS             99..542
                     /locus_tag="NOB43_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0982631.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(548..1732)
                     /locus_tag="NOB43_001776"
     CDS             complement(548..1732)
                     /locus_tag="NOB43_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HCI0982632.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2000..2698
                     /locus_tag="NOB43_001777"
     CDS             2000..2698
                     /locus_tag="NOB43_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI0982633.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2705..3382
                     /gene="nth"
                     /locus_tag="NOB43_001778"
     CDS             2705..3382
                     /gene="nth"
                     /locus_tag="NOB43_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCI0982634.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3508..4041)
                     /locus_tag="NOB43_001779"
     CDS             complement(3508..4041)
                     /locus_tag="NOB43_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982635.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4338..6719)
                     /locus_tag="NOB43_001780"
     CDS             complement(4338..6719)
                     /locus_tag="NOB43_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI0982636.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6709..7356)
                     /gene="recU"
                     /locus_tag="NOB43_001781"
     CDS             complement(6709..7356)
                     /gene="recU"
                     /locus_tag="NOB43_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HCI0982637.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7420..7959
                     /locus_tag="NOB43_001782"
     CDS             7420..7959
                     /locus_tag="NOB43_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HCI0982638.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8049..8468
                     /gene="gpsB"
                     /locus_tag="NOB43_001783"
     CDS             8049..8468
                     /gene="gpsB"
                     /locus_tag="NOB43_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HCI0982639.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8490..8857
                     /gene="rnpB"
                     /locus_tag="NOB43_001784"
     ncRNA           8490..8857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="NOB43_001784"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9066..10232
                     /locus_tag="NOB43_001785"
     CDS             9066..10232
                     /locus_tag="NOB43_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HCI0982640.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10278..11774
                     /locus_tag="NOB43_001786"
     CDS             10278..11774
                     /locus_tag="NOB43_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HCI0982641.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11855..12538
                     /locus_tag="NOB43_001787"
     CDS             11855..12538
                     /locus_tag="NOB43_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0982642.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13183..14373
                     /locus_tag="NOB43_001788"
     CDS             13183..14373
                     /locus_tag="NOB43_001788"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCI0982643.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14475..15428
                     /locus_tag="NOB43_001789"
     CDS             14475..15428
                     /locus_tag="NOB43_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCI0982644.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15497..16846
                     /locus_tag="NOB43_001790"
     CDS             15497..16846
                     /locus_tag="NOB43_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0982645.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17029..17352)
                     /locus_tag="NOB43_001791"
     CDS             complement(17029..17352)
                     /locus_tag="NOB43_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982646.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17481..18644
                     /locus_tag="NOB43_001792"
     CDS             17481..18644
                     /locus_tag="NOB43_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI0982647.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18714..20063
                     /locus_tag="NOB43_001793"
     CDS             18714..20063
                     /locus_tag="NOB43_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0982648.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20108..20539)
                     /locus_tag="NOB43_001794"
     CDS             complement(20108..20539)
                     /locus_tag="NOB43_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0982649.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20927..23569
                     /gene="alaS"
                     /locus_tag="NOB43_001795"
     CDS             20927..23569
                     /gene="alaS"
                     /locus_tag="NOB43_001795"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCI0982650.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23769..24365
                     /locus_tag="NOB43_001796"
     CDS             23769..24365
                     /locus_tag="NOB43_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0982651.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24487..25635
                     /locus_tag="NOB43_001797"
     CDS             24487..25635
                     /locus_tag="NOB43_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0982652.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25673..26086)
                     /locus_tag="NOB43_001798"
     CDS             complement(25673..26086)
                     /locus_tag="NOB43_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HCI0982653.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26165..26596
                     /locus_tag="NOB43_001799"
     CDS             26165..26596
                     /locus_tag="NOB43_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HCI0982654.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
BASE COUNT         8810 a         4607 c         5523 g         7658 t
ORIGIN      
        1 tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg aataggaaac
       61 aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga caactgctaa
      121 tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca gaaatggaaa
      181 aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc gggaaaatcc
      241 ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga gccatcagta
      301 agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc gaagagaata
      361 aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat agacacgagc
      421 aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg tcaaaagaag
      481 aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga agtagcaaat
      541 gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa aatccgaata
      601 ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg ccgatgacgc
      661 gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg ttatctgaga
      721 cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg aaaccataac
      781 agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat gtgatgaata
      841 gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct gaaaattttt
      901 tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca atcaaagaga
      961 agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat tgagaaaaga
     1021 tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat aaaggaataa
     1081 cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg gagaaactta
     1141 aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag ccataaacgg
     1201 catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc aactcagcta
     1261 atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca cccatccatc
     1321 caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca tataaggtgg
     1381 agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc catatcgaat
     1441 ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata ataaggatcg
     1501 gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag aaggcagcta
     1561 gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg gagtgagaat
     1621 aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat ccagtgaata
     1681 agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac atgtaaaaac
     1741 tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt ttgtttcctt
     1801 gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa agtgaagata
     1861 cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc tgaccgatca
     1921 gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac gtatactgtg
     1981 attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg gacaaacagt
     2041 catatctaat cttttactta aaaattatca taggatcggt ctacaatctg aagaattttt
     2101 atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg atttgcagat
     2161 gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg atcgtctcgt
     2221 aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag cagatcgata
     2281 taatctttac cccatctatg atctattagg tgagtattta aaaacacaag aaaaaaaata
     2341 cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg aacaagaatt
     2401 tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag aagaagacca
     2461 ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc aggcttatag
     2521 ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac gtacaaaaca
     2581 acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag aagtagaaca
     2641 gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg aggagtagcg
     2701 gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg gaatgtttcc
     2761 cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg cagtgatctt
     2821 aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt ttgcctcttt
     2881 tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta aaataaaaac
     2941 gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc agctgattga
     3001 acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc ctggtgtagg
     3061 cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa tcgcagtaga
     3121 tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg ctacggtcat
     3181 ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa agacacatca
     3241 tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt gcgaggtatg
     3301 tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag aaaaggcgct
     3361 aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg tatgaattat
     3421 cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa gtaaatgtac
     3481 atactcagta gctaggatgg taacttatta caatttattg cgataaaaat aaaagttgtt
     3541 atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac ctataaaata
     3601 agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag gtgtaataaa
     3661 aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa tggatttggg
     3721 cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata aaaaagtgag
     3781 aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc ttaaaagtac
     3841 agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta ataataaaca
     3901 aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata aaaaaagatg
     3961 gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga agccttcttt
     4021 caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa tgggattatt
     4081 aagaagttgc actaaataaa agactagtgt gtatttagcc gatttaatta taaacaagta
     4141 aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt taagctaaat
     4201 gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat acagcttggt
     4261 acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc acgcttgtag
     4321 acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg
     4381 tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat
     4441 gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc
     4501 tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta
     4561 gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag
     4621 ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct
     4681 ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt
     4741 gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac
     4801 gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga aatcgaataa
     4861 tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt
     4921 gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg
     4981 atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata
     5041 taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg
     5101 tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa
     5161 gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct
     5221 tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt
     5281 tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca
     5341 ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag
     5401 tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca
     5461 gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa
     5521 ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg
     5581 tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca
     5641 acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt
     5701 ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc
     5761 ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta
     5821 gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct
     5881 tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct
     5941 cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc
     6001 atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac
     6061 atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag
     6121 taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct
     6181 tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc
     6241 aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca
     6301 gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc
     6361 gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt
     6421 tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta
     6481 gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct
     6541 acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat
     6601 aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca
     6661 ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt
     6721 cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg
     6781 aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg
     6841 tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt
     6901 caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg
     6961 ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga
     7021 tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt
     7081 atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt
     7141 aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc
     7201 gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt
     7261 gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt
     7321 ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca
     7381 ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc
     7441 tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc
     7501 caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa
     7561 tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa
     7621 ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt
     7681 aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat
     7741 gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt
     7801 tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa
     7861 acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg
     7921 ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat
     7981 caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag
     8041 gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa
     8101 caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag
     8161 attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg
     8221 caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag
     8281 aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg
     8341 aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac
     8401 ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc
     8461 aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca
     8521 ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa
     8581 accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat
     8641 gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga
     8701 acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa
     8761 gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct
     8821 ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag
     8881 gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa
     8941 tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat
     9001 ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat
     9061 tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag
     9121 cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg
     9181 cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag
     9241 atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa
     9301 acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg
     9361 gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag
     9421 caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa
     9481 ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg
     9541 atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat
     9601 tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat
     9661 tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata
     9721 atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag
     9781 aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag
     9841 atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag
     9901 aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg
     9961 ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag
    10021 aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga
    10081 gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca
    10141 aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc
    10201 gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat
    10261 gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc
    10321 ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag
    10381 ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa
    10441 tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg
    10501 aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac
    10561 cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa
    10621 aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat
    10681 taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc
    10741 tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta
    10801 aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag
    10861 actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg
    10921 aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga
    10981 ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa
    11041 tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg
    11101 ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat
    11161 cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt
    11221 tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt
    11281 cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc
    11341 tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg
    11401 ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa
    11461 atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc
    11521 cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa
    11581 tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag
    11641 agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac
    11701 atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat
    11761 atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt
    11821 tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga
    11881 ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag
    11941 agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac
    12001 gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga
    12061 ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc
    12121 gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga
    12181 actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat
    12241 cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga
    12301 actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa
    12361 tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga
    12421 agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg
    12481 gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg
    12541 gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac
    12601 ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga
    12661 acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg
    12721 gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg tcacagtcct
    12781 tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa ttaaaaattg
    12841 ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata aataaattaa
    12901 atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt gttgtattta
    12961 tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat actatataag
    13021 tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt ctcataatca
    13081 gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca cgatatatgt
    13141 ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc caaagaacta
    13201 acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata caatacgatc
    13261 gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa gatgatcaat
    13321 ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa agcatgtatt
    13381 gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa tggttcgctg
    13441 aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga agcagcaatc
    13501 gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat gacaaaagaa
    13561 gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg ccgcttatcc
    13621 ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa aaaagcaaag
    13681 gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg tgttttctcc
    13741 atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa atatggactg
    13801 atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc aggaaccgtc
    13861 aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc gaaagctata
    13921 ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt gaaagctaga
    13981 agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc tgcattggct
    14041 tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga aaatgctaat
    14101 tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga aacacctatt
    14161 actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa gctgatcgaa
    14221 catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac aggcaggatc
    14281 agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt agcagtttat
    14341 caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc gtctatttaa
    14401 aattagagaa catgttcacg catatattgt taatcatctg aagatagtag taaaaaagat
    14461 cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa attggttcag
    14521 agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg acagatatac
    14581 gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta atggattacg
    14641 aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat ttggctgctc
    14701 ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac gtgactgggc
    14761 tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg ccaagttcaa
    14821 tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact cttcagcgtc
    14881 ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat tattattatg
    14941 tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct tatgcaacct
    15001 tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca atcaaagaag
    15061 gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat atgccagatg
    15121 cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt catcgaaatg
    15181 ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct attcaaaaaa
    15241 tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca atagcagaat
    15301 cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt tcgccgaaat
    15361 acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa ttggtagaga
    15421 cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt ggctatggta
    15481 tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag taaaaataga
    15541 aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta tgggcacagt
    15601 gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag gatccgccag
    15661 tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag gactaacagg
    15721 agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata tcgaacggat
    15781 ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt attttccagc
    15841 aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat ttggtctttc
    15901 ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt tgatcaattt
    15961 tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca agcttattcc
    16021 tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact tccaactgtt
    16081 tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg gcttgctagc
    16141 aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag aattgaaaaa
    16201 gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca tgatcgttta
    16261 tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg caggaaacag
    16321 caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa gactggtcac
    16381 agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta ctggaatgcg
    16441 tctcccttat gttattgcaa aagaaaacaa cctgcctttt agcaagctct ttgctaaact
    16501 tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca tcgctattgg
    16561 catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg tcatttggat
    16621 tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac ctgatttgtt
    16681 tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca ttggagggac
    16741 ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg ggatagtatt
    16801 gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa aacattcgaa
    16861 ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga ggagtacgtg
    16921 gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt gtctacgatg
    16981 aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt actttgattt
    17041 gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca agcaaccaga
    17101 aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag acaaagcatg
    17161 tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat tgaagactag
    17221 catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag ttctttttct
    17281 tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa aaacaaagta
    17341 catattcagc atctcgacac cccctttgtg tttatcttac tttactttga aagaaatgag
    17401 aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa gagagataca
    17461 aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt gcgctgattg
    17521 tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa tatcgaaagt
    17581 atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt tatttattgt
    17641 gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc caaatgacag
    17701 ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac aacacggtat
    17761 tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta tttttggaac
    17821 cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat tatttccggc
    17881 tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt gaattgacgc
    17941 agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat gtgaatgatt
    18001 tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta tttacattta
    18061 tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag actgtctcat
    18121 tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt attaatttgg
    18181 tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct catatctggt
    18241 ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc aatggatgga
    18301 cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa cgaatttctt
    18361 taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt ttaagctggt
    18421 tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg cagatgagtg
    18481 cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta aatatcttgc
    18541 tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac acatatactg
    18601 ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc aaaaacgctt
    18661 tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca cgaatgaata
    18721 attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca aagggcttca
    18781 aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga aaaaatatca
    18841 ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct ttgtttgaaa
    18901 aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt agggaactag
    18961 ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg gagatccgtg
    19021 tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg catcaccaac
    19081 agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat gaacaagcgc
    19141 tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca ttggatatgg
    19201 gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg cagtttttag
    19261 ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac atggaaaatc
    19321 caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa aattggctga
    19381 tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca attggtcatc
    19441 cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt gccgattact
    19501 tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca agagagagaa
    19561 aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg actgatttag
    19621 ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa attccagaag
    19681 atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta aaaggaacgg
    19741 ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa aaattgggcg
    19801 tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac gatcgtaata
    19861 gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt ggtcttgtga
    19921 agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg gcaattgcag
    19981 aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact gctcgtaaaa
    20041 ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt gtcacaatct
    20101 cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct tcaataaaag
    20161 gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc atttcagcta
    20221 ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct tcaagcaact
    20281 gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc ggcttgaagc
    20341 aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga tcaagaaata
    20401 gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca ggaatccctt
    20461 gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc cattcatccg
    20521 ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat gtattgattc
    20581 ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga aaataaaaat
    20641 tgagatattg acagtgatca atagaatgcg tatactaatt aagtacgaaa aggatatgat
    20701 ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag tcactaatca
    20761 aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt atcgagttta
    20821 agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc gtccttggct
    20881 gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga aacaattaag
    20941 tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac atacgattga
    21001 acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca actctggtgt
    21061 tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa gaatcacaaa
    21121 tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag cacggcacca
    21181 tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa atgaagccat
    21241 ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc cagaaaaact
    21301 ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg aagaagttgg
    21361 cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg gtgcaggccc
    21421 atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg atttagcaga
    21481 agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa tctggaactt
    21541 agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc ctcataaaaa
    21601 cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg cgtcaacgaa
    21661 ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa gcaaacaagt
    21721 aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag atcatattcg
    21781 cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga gagggtatgt
    21841 cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta ttgaacaagc
    21901 attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt atcctgaagt
    21961 acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac gtttcaatga
    22021 aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa aaaacgaaaa
    22081 cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg gcttcccggt
    22141 agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg ctggttttga
    22201 aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg aaaaatcaat
    22261 gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca ttggatacac
    22321 agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc ttttgaatga
    22381 agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg cagaaatggg
    22441 tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg tagcagttgt
    22501 tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag taaaagcacc
    22561 aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca atcggatcat
    22621 caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac ttggcgagca
    22681 tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact ttacccactt
    22741 tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg aaaaaatctg
    22801 ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa acatgggtgc
    22861 aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata ttggcggctg
    22921 gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg gaatcttcaa
    22981 aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg taacaagtaa
    23041 agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag caacaattgt
    23101 taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac agcaagtaag
    23161 agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac aagctggtga
    23221 tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac aagtaaaagt
    23281 gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa atatttcaga
    23341 tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg caatgacgaa
    23401 agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg caccgaaagt
    23461 aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa atcctgctgg
    23521 tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg gcgtttacgt
    23581 ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg cgaagacaaa
    23641 caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat ggtcggattc
    23701 ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa ataaaaaggg
    23761 gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg atcttgttag
    23821 caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta ggattcatta
    23881 gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc ccaaaagatg
    23941 gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat gccatgccaa
    24001 caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt cccagagtac
    24061 ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat aaatcaataa
    24121 cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc ttagtgttag
    24181 gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta gactctgctc
    24241 ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa gcaataggtg
    24301 cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg ttgaaaccag
    24361 aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag gaagagagga
    24421 gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact agaaggggta
    24481 aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca gcggacaaaa
    24541 aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt tgtctctaag
    24601 ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt gaacagtcta
    24661 tcagatactg cttcatccat attgactttg atcggattta aaattgctgc aaagccagca
    24721 gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt atttgtttcg
    24781 atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa aatcatccat
    24841 ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc catctttttg
    24901 aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc tgaaacattg
    24961 agagctacag caacagatag ttataatgat gtctttacta cactggctgt attgctttca
    25021 gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt tgctttagca
    25081 ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga actattagga
    25141 agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc ttgcgatgat
    25201 atacttggct atcatgattt attggtgcat aactatggac ccaataaacg ctttgcatca
    25261 gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat tattgatctg
    25321 atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt ggatccaatg
    25381 cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat tcttcttgaa
    25441 acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa aacgctgcaa
    25501 tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga aagaatctta
    25561 cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt tgatcacaat
    25621 tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta atttaaagag
    25681 tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct gctcctttat
    25741 ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga agttcttgga
    25801 ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg accgtagaaa
    25861 ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg tttttcttta
    25921 gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc cctatagaaa
    25981 gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca cctccactag
    26041 gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa agagattctc
    26101 ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg tgagaggtta
    26161 gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca tctattggtc
    26221 attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca caggtcctta
    26281 ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag gtttgcggcg
    26341 ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt ggaaagaccg
    26401 agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg tgcaaatgat
    26461 gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc aagtagtcct
    26521 ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc cttatacgaa
    26581 aaaaagaaaa agctaatt
//
LOCUS       DAIGTA010000041        25502 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.041, whole genome shotgun sequence.
ACCESSION   DAIGTA010000041 DAIGTA010000000
VERSION     DAIGTA010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.041"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            133..3660
                     /locus_tag="NOB43_001800"
     CDS             133..3660
                     /locus_tag="NOB43_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HCI0982655.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="NOB43_001801"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="NOB43_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HCI0982656.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQVIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="NOB43_001802"
     CDS             7448..7789
                     /locus_tag="NOB43_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0982657.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="NOB43_001803"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="NOB43_001803"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCI0982658.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="NOB43_001804"
     CDS             9146..11566
                     /locus_tag="NOB43_001804"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCI0982659.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOB43_001805"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOB43_001805"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCI0982660.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="NOB43_001806"
     CDS             13000..13737
                     /locus_tag="NOB43_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0982661.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="NOB43_001807"
     CDS             13751..14566
                     /locus_tag="NOB43_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI0982662.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="NOB43_001808"
     CDS             14579..15226
                     /locus_tag="NOB43_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0982663.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="NOB43_001809"
     CDS             15242..15898
                     /locus_tag="NOB43_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0982664.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="NOB43_001810"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="NOB43_001810"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCI0982665.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="NOB43_001811"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="NOB43_001811"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCI0982666.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="NOB43_001812"
     CDS             18240..18758
                     /locus_tag="NOB43_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI0982667.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="NOB43_001813"
     CDS             18865..19365
                     /locus_tag="NOB43_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0982668.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="NOB43_001814"
     CDS             complement(19645..20565)
                     /locus_tag="NOB43_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCI0982669.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="NOB43_001815"
     CDS             20730..21743
                     /locus_tag="NOB43_001815"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HCI0982670.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOB43_001816"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOB43_001816"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCI0982671.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="NOB43_001817"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="NOB43_001817"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI0982672.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="NOB43_001818"
     CDS             complement(23383..24144)
                     /locus_tag="NOB43_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0982673.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="NOB43_001819"
     CDS             24333..25427
                     /locus_tag="NOB43_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI0982674.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4423 c         5385 g         7247 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagtcatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtggacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 gg
//
LOCUS       DAIGTA010000042        24579 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.042, whole genome shotgun sequence.
ACCESSION   DAIGTA010000042 DAIGTA010000000
VERSION     DAIGTA010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.042"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(153..551)
                     /locus_tag="NOB43_001820"
     CDS             complement(153..551)
                     /locus_tag="NOB43_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCI0982675.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="NOB43_001821"
     CDS             complement(548..1321)
                     /locus_tag="NOB43_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI0982676.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="NOB43_001822"
     CDS             complement(1318..2001)
                     /locus_tag="NOB43_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI0982677.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="NOB43_001823"
     CDS             complement(2168..3055)
                     /locus_tag="NOB43_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0982678.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="NOB43_001824"
     CDS             complement(3052..3921)
                     /locus_tag="NOB43_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0982679.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="NOB43_001825"
     CDS             complement(4058..5344)
                     /locus_tag="NOB43_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0982680.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5617..6195
                     /locus_tag="NOB43_001826"
     CDS             5617..6195
                     /locus_tag="NOB43_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0982681.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6195..7124
                     /locus_tag="NOB43_001827"
     CDS             6195..7124
                     /locus_tag="NOB43_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0982682.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7121..8857
                     /locus_tag="NOB43_001828"
     CDS             7121..8857
                     /locus_tag="NOB43_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI0982683.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="NOB43_001829"
     CDS             complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="NOB43_001829"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HCI0982684.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9753..10262)
                     /locus_tag="NOB43_001830"
     CDS             complement(9753..10262)
                     /locus_tag="NOB43_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HCI0982685.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="NOB43_001831"
     CDS             complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="NOB43_001831"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCI0982686.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11563..12654)
                     /locus_tag="NOB43_001832"
     CDS             complement(11563..12654)
                     /locus_tag="NOB43_001832"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HCI0982687.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="NOB43_001833"
     CDS             complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="NOB43_001833"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCI0982688.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="NOB43_001834"
     CDS             complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="NOB43_001834"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCI0982689.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="NOB43_001835"
     CDS             complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="NOB43_001835"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCI0982690.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16617..17591)
                     /locus_tag="NOB43_001836"
     CDS             complement(16617..17591)
                     /locus_tag="NOB43_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HCI0982691.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17572..19455)
                     /locus_tag="NOB43_001837"
     CDS             complement(17572..19455)
                     /locus_tag="NOB43_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HCI0982692.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19473..21698)
                     /locus_tag="NOB43_001838"
     CDS             complement(19473..21698)
                     /locus_tag="NOB43_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI0982693.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="NOB43_001839"
     CDS             21813..22847
                     /locus_tag="NOB43_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0982694.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22914..23927)
                     /locus_tag="NOB43_001840"
     CDS             complement(22914..23927)
                     /locus_tag="NOB43_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0982695.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24005..24193)
                     /locus_tag="NOB43_001841"
     CDS             complement(24005..24193)
                     /locus_tag="NOB43_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCI0982696.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7065 a         5342 c         4397 g         7775 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atacaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccccatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcatcatac
     5401 caaaatttga aaacggtttc tttattattc agatacttca aaaatttctc ctaaaataat
     5461 aaaaaaatac aaatcaacta tgacaaaagg aataatctta gcatctagac caaagatcga
     5521 aatggtgagg tttctttaaa ataaaaatat ccttgcattt tctcctagaa ataagtattt
     5581 ttaaattaca agactattct taaggcgggt aaaaaaatgc caatacgcgt aattcttatc
     5641 gatgatgaac agacgatttt agatggaatg aaacagttga tcaattggtc tgagcacggg
     5701 tttcaattaa tagggacttt ttccagtccg ctgaaagcgc ttgatttttc tttggtacat
     5761 gcaatcgata tcgtggtcac agatgtaatg atgcctgaat taaatggaat cgaattatcg
     5821 cggctattaa aacagcaaca acctgaaaca cagatcctta tcctctctag ctatgatgaa
     5881 tttgatatgg ttaaagattc ttttaaagaa ggcgtcgctg attatctttt aaagcctcga
     5941 ttgagtcctg atttttttct aaattcctta actgccgttt cacaaaaaat caaaaaaaag
     6001 cccaacaaaa gcccaatcac caatcgttat gagcagatct gcgagaatct ttcacagcag
     6061 attgctggac aaactcgtcc attgcttgac cctcttcttt ttgaacacac cttgtttttc
     6121 tgttatatac cgaaaaacgg ccattcagtt caaaacaagg ctctaaacaa aaacagtcga
     6181 tcacccattc attgatggat agcgacgatt cgtttactat ttatcctgtt tctacctttt
     6241 cggaagaatc cggctatgta atcaatactg attccaaaga tacacttagg aagtttgttc
     6301 aaaagtttcg tcaagaagtt tttccaggtg atttttttgt tgtttctgat tcttttgcaa
     6361 tccaagatat caatgaaata ttccaagaga tcagaaattg caccaaagga caacgtttct
     6421 atcataaggg aaagaacctt gcttatcagc atgaacttct tccgttatta accaaccacg
     6481 agcagcaagc aagtagttat ttaacaaaaa tcgttcataa agactacgct ttagctgtca
     6541 aagaacttga gaatttcttc acgacgatat tggaacagcc tattgatcca gcttatttga
     6601 aacatgaggc aatcaatcgt ttctatgcat tactcaacgc tttggctgac gagcatgttg
     6661 ggaatgaaga actttctttg ctcaagatcg cccttccttc tttattagcc gatgctgagt
     6721 atttcgaaga tttttctatt cttgtcaaag aaacacttga gaaactcacc cacttttctg
     6781 caaatgcaaa aaaagacaat ttcgatatct tgactttgat ctacgagttc gtccaggaaa
     6841 attatgagaa agaaatcaat ttacaacttt tatccgaaaa atatcatttt tcatatagct
     6901 atctctcagc catctttact gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag
     6961 tccgtatcag taaagccaag ctctttttga cggaaacacg gcttactttg acggaaatct
     7021 gtgagaaagt cggctatacc gaactgggtt atttctccag agtttttaaa gaagagacag
     7081 gaatgacacc ttctcaatac cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga
     7141 gcatgaactc tttgccaaac ttctgttcat tttgttcatc ggtctttttc tgcaagccat
     7201 cgtcatttct ttgtttattt atcatcgatc aagggatgcc tatatccagc tgttcaatca
     7261 atcgaatgat gtggtactaa aaaagattca atctgaattt gaaagtttga atgatacaat
     7321 cgagaataca ttagccgctt ttgattctaa tccagctgtc aaaagctatt tttccaatga
     7381 tccagcccaa catatggaac agcttcagca actaagaaca atccaaaaaa tgaatgactc
     7441 tctttcaaaa atccatccaa tgatcgatta cgatgtattg atctttggag aaaatggaag
     7501 aacttttgtc ggaaacgaca tgctcactgc cgtatctgcc gattcttttt ttcaatctgc
     7561 gattgctcag agagtgaatg aacgtgctgc tgatacacaa atgctttttg cacaccacgg
     7621 attgactctt cgcgataaga aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac
     7681 attgaatcac gtttacggat atgctgtttt atcgatctca tccaagcaac tagcgaatct
     7741 ttttcaatct gtagtaaatc ctgagatatc gaagatctcc ttcatgaacg aagaacagac
     7801 gatcatcgca tcaaatgaag aaaatacaat tgggagccga tcaatgattt tcaaaaaact
     7861 aacagtaggt gaaacaacga tttcaaatgg acagcagttg acccgtcttc ctctgtaccg
     7921 ccaggattgt acattactca gtcaagtcga tcttcattct ttatctaacc aaatgggcgt
     7981 gatttttccg attattttgt ataatatcgt gacacttgct tttgctggct cattggtatt
     8041 tatgtatttg gatcgacaca caaaatcgat ctaccgcttg attgattcgc taaaacggct
     8101 agaggaagat ggcttaaaag ctactgttcc tgtacaagga agccatgaag tccaattgct
     8161 agggaatacg atcaatcaat tgctaagtaa tgctcagcat cattatgaac agacgatcca
     8221 agacgaaaag aagaaacgtt cgcttgaaat ccaaactatg caagcacaga tacagcccca
     8281 ttttatttat aatacgctga ctagcttgaa atttttgatt tggcagaaaa aaacagatga
     8341 agcagttcaa ggaatcgaca gtttcattac tttactaaga agtacgattg ggaaaaaaga
     8401 agaagtgatt ccagtcaagg aagaaatcaa aagcgtacaa agttacatcg atcttttgag
     8461 tatgcgatat ggcgaaagaa tctcggctaa aataatgatt cctgatgaac tgcagtcatt
     8521 atctatgccg aatatgatcc ttcaaccaat tatcgaaaac gcctatcttc atgcttttca
     8581 caataaaacg caaggattca tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt
     8641 cgaagtgatt gataacggcg atggcttcga tactgaaaat accaaacaaa aaaatgatca
     8701 tttttcagga atcggcatca gccatgtaga tgagcggata cgcctaatgt atggcgatgc
     8761 atatggctta acgatccaat cagtgattgg gacaggaacg actgtaacga tttgtctacc
     8821 gcttcttcct aaaaatcaat cagaatatca aaaataaaga atagccaagc gctgattttt
     8881 ttattttaag ttaaataaat caatcagtat tcttgacttt catctacgcg tctcttctac
     8941 tgtcagcact ggataacagc ccaatatttg actttctcct ccgagcatct tgatttcttg
     9001 gagcgcattc tctactaatg tcattggacg gtccaacaac aaatcgatca cgaaaaaata
     9061 ttctcccaag ctagttttca atggtcggga ttcaatctta cttaagttga tttcccgcca
     9121 gccaaaagct gccagcattt tatgaagcat ccctggccga ttagcaggta gtgtcaagat
     9181 gacactcatt tttactggag ctgactgctg gctggtcatc tttcggtcac cgacgatcca
     9241 aaaacgtgtc tggttcaact cattatcttg gatattctca gctaagatct ccaatccaac
     9301 atgctgtgct gtttctaatg aagcaatcgc tgctgcgtct tctttcggat gttctgctac
     9361 atacattgct gcagcagttg ttgattctgt tgctactaaa ggaacattag gataatgcgt
     9421 ttctaaaaac tgttgtgatt gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt
     9481 tgttgctgga ttgcctaaaa gctgctgctt gataggaaga acgatttcac ttttaacttc
     9541 gacttctgga tgtttggaaa gaagatcgat tgtgtgatga acagctcctt ccaatgaatt
     9601 ctctacagga acgacagcca gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg
     9661 gatggaagca tacgcagtca attgttctgt aggaaatagc tgacaagccg cctgataagt
     9721 gaatgaactt tctggcccta gatagctgac gttcatatgc ttttgatcct ttctataatg
     9781 gtatcgatga tcttttctgg tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct
     9841 tcataccaag aaagtcgttg tgccaataat gcttttattt cttctcttgt ttttccaaga
     9901 gctaaaggtc gaatagacgt ttcatcttgt tggatacgat caactagaca gtccgcttct
     9961 gcctctaagt aaagaacaat cggctgtgtt tttaaaaaac gccgattttc tgcactttgg
    10021 acaatccctc caccagtcgc gataattttg tcttcatttg acagctttct taaaatatct
    10081 gactccactt ttcgaaagct tttttcaccg taatagtgaa aatattcggc aatcgacaat
    10141 tggatatgtt cctcaatctt tgtatctaaa tctacatact ctttttgtaa acattgagct
    10201 aaccctttac cgattgttgt ttttccagcg cccatgaaac caatcagcaa aatgctagcc
    10261 atgagcttct cctcctgaca caagttctgc taaatcgtca aaaaatgccg gataagagat
    10321 tgaaacagct tcagctcctt ctagttcgca aggtccatca gctatcaaag cagctacttg
    10381 cagcatcata ccgattcgat gatcgcctct gctggacact tttgcgccat gcagaggtgt
    10441 cggcccatgg atgatcagac cgtctgctgt cgcttttatc tttgctccca ttttctgtaa
    10501 ttcttctgcc accgcatcaa ttctgttggt ttcttttact tttaattctt ctgcgtcttt
    10561 gatgatcgtg attccttctg cttgagtagc cactaaagct agaatgggca attcatcaat
    10621 cagacgcgga atgatttctc caccaatcgt tgctttcttc aaatgactcg tcttgacact
    10681 taaatcagcc gattggttct gttcattgtg attcgtctgg gtaatcgctg cgcccatctc
    10741 ctccaacaca tctaagatac cagttcttgt tggattgacc ccgacatttt ttaacaacag
    10801 ttggctttcc ggaacaagaa gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc
    10861 tggaacagtt atctgttgac cagttaattt ttgcggtccg gtcactatga tcgttttatc
    10921 ttccactgtg atccttccgc caaattgacg aatcatttct tccgtatggt tacgggaacg
    10981 ttctttttca acgattacgg atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga
    11041 tttgacttgc gcactggcta caggcatatt gtatcggata ggtgataaag agcgggttcc
    11101 tgtcacagtg attggtagat actggtcatt ttcttctcct tgcaagtcag cgcccatctc
    11161 gcgtaaaggt tccatcactc gccccattgg acgtttagac aacgaagcat ccccgaacag
    11221 agtagtcgta aaaggctgtc cagccaaaat acccatcaat aaacgtatgg tcgtaccgga
    11281 gtttcccatg tcaattgatt cggttggttg gacaaatgag tggctaccgc gaccatgaat
    11341 cttgatcacc tcttcctctt cttcgatctc gacacctaat tgttggaagg catgtaaagt
    11401 actcagacaa tcttctgcgc gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc
    11461 tccaaacatg atgctgcgat gggaaattga tttatctgct ggtatcctaa cagtccctct
    11521 taatccatgt atttgttgta ataattgcat ttatccagcc tcctatttga tccagcaatg
    11581 ataactggta ttagacataa tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa
    11641 actgatttgc agtattccta aaatatcttc cctggtctct tggatcttca aattaatcaa
    11701 agaaactccc gcttttccga tcagtccagt tacttctgca ataacgccag gttcatctgg
    11761 cacatcgata aataaatcaa aaaaggcagg aatcgcgcct tgcttatgga caggcaactg
    11821 gtctcgactt tcttttgccc gattgaaaaa agaaaagatt tccgattggt tctcagtcat
    11881 gatccattct gctatttgtg tcatttcttg ttgccaatct gccaatcgtt ccaataatat
    11941 ctgcttattg ctcaacaaaa tatctgtcca catgacagga tctgaggaag cgatcctagt
    12001 gatatctcga aagcctcctg ctgccagttg tttggctcgc ggatactctt gattgaattg
    12061 ttctgcctga ttgactaagc cagctgccag aatatgtgga aaatgactta gcattcctgt
    12121 tatacggtca tgttctcttg ctgtaagagt tacatatttt gctttggttc cgcaaaatag
    12181 ttcttgcagt ttttcaacat cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc
    12241 attttcaaat agtttagcat ctgctgcctg tatacctgat ttatgagaac cagccattgg
    12301 atgtccaccg acaaaccgaa gatttttctg ctcagcggat gtcacgactt gctgcttcgt
    12361 actgctgaca tccgtaatga tgacgtgatc agacaagttg attctttcaa ggacatcaag
    12421 ataagctaag gttgtacgga cgggaacggc taataagata acgtctgctt gttctgcacc
    12481 tgtttcaaaa tcacttgcaa cgtaatcaac gatctgctgt tctactgctt gctcacgggt
    12541 ttttgactga ctatcccaac caactactat cagttctgga ttggtctgac gaatacaaag
    12601 tgccatagaa gcaccaatca gtccaagccc cacgataaaa acatgttgtg ccatcttatt
    12661 tgcccccttt ttagtaatgt ttcaagtagt cacggtactc cttcactgca gctttcaact
    12721 caacaagcga atcacttggg aattttgaca atagctctgt cgctaccaca gtggctacaa
    12781 cattttccgc aacgacgcta gctgcaggaa ctgctgtact atccgaacgt tctacacttg
    12841 ctttgtaagg ttcttttgta tcgatatcaa cactttgaag tggcttgtac aatgtaggaa
    12901 tgggtttcat gaccccgcga atgacaagtg gttcgccatt ggtcattccg ccttcgaagc
    12961 cgcctagatt attggtacgt cggaaatagc ctctttcttc ttcccatagg atctcatcca
    13021 tcacttctga gcctggtaat gaaccagaag tgaatccgac cccaaattct acgcctttaa
    13081 aggcattgat actaaccaca gcttgtgcga ttttggcatc tagcttcgtg tcccattgta
    13141 cgtagcttcc taatccagct ggaacgcctc caacgagcac ttctacaatt cctccgatcg
    13201 tatctccatt tttctttgtc tgatcgatca aatcttttat tctttgctca actgctggat
    13261 caacaactcg tacttctgac gcttcagaaa tttctttgat ttcttgaatc gagatatttc
    13321 caggtatttc tgcttggatt ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa
    13381 gttcttccag aattttcttg gcaattgcgc cgattgctac acgcatggtc gtctctcttg
    13441 cagaggaccg ttcaagcaca ttccgaagat ctcgatgatg gtatttcata ccgcctacca
    13501 aatccgcgtg tcctggacgc ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca
    13561 cttctgctac agacatgaca gttgtccaat ttttccaatc tttattttct accactaaag
    13621 tgacaggtga accaattgtt ttgccgtgac ggatgccaga cgtgatccga acacgatctt
    13681 tttcgatctt catccttcct cctctgccgt aaccagcttg tctgcgagcg agttcgtgat
    13741 tgatttcttc ttctgacaga ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt
    13801 ctggtccatg ggattctccc gcagtcatat aacgcatctt acagtcctcc taagtaatct
    13861 ttgaatgtct ctgtgggaac aggaacgatt tttgcttgcc caatcttttc tagcaagatg
    13921 atattcaatt ggcttcctct tgctttctta tcatgggtta tcgcgtggaa taattcatct
    13981 ggatgactta gatcgtacgt aatcggcaga tggaattttt gaagtatcct ttctaaagca
    14041 gctgtcgatc cagttggaga caagccgatt ttttctgcat gagaagtgat ggctaccatt
    14101 ccaatagcta ctccttctcc atgactgact accccatatc ctgctgtatt ttcaattgca
    14161 tggccaattg tatgaccaaa atttaaaata agtcgatttc cttggtcaaa gacatcttct
    14221 tccactactt ttcgtttgat ttccaacgta gcagtaatga ttggaacagc atgttccaga
    14281 agatcttttt cgtctttcag ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct
    14341 gctgatttga tgatttcagc gattccttct cgtaaacgac gtaccggcaa agtttttaga
    14401 acctcaggat caatcaatac accagctggc tggctaaatg ttccgacaag gtttttcgct
    14461 ttgtttgtat tgactgctgt cttcccgcca atactagaat ctacttgtgc aagtagcgta
    14521 gtcggaattt gaacgaaatg gatcccacgc atgaacgtcg aggccacgaa tgctgctaga
    14581 tcacccacca ttcctccacc aagtgcaagt atcccatcgc tgcgggtaaa atcattatct
    14641 gctaaaaaat cgtataactc agctgcttgt tctaaagatt tactggtctc acccgccggt
    14701 acgattgaaa ggactggttc aaaattagct tgtctcaatt ggaacatgat tttttctgca
    14761 tatagtggag caacgtttgt atcagtgatc acagctactt tttgaggtct ccaaatcgtt
    14821 tgaagccatg atccagcctg ttctagtgcg cctttttcaa tatgaatatc gtatttttgg
    14881 ttatcaacat gtacagtaag cattcgtttc acttctctct tttaaaaagc tggaattaat
    14941 cgagtgtctg aatcttttcc attgcttctt tcatgatcgc aacttctttc atcatgcgtg
    15001 agtaagtctt ttcattcaac gattggggac cgtctgacca agcatttgca ggatcaggat
    15061 ggatctctac gatcatgcca tctgctccgc ttgccacacc cgcacgagcc attggtggta
    15121 caagttccca aattcctgta ccatgacttg gatcaacaat cacagggaaa tgagttaatt
    15181 ttttcatcaa tgggacagca cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc
    15241 gaatcccacg ttcgataaaa atgacaggag atttgtcttc gactgcaatg tattctgcag
    15301 cattaagcca ttcattgatc gtaccggaaa ttccacgttt caatccaaca ggtttacctg
    15361 ttttaccgac agcagatagc agtttaaaat tttgcatatt acgtgcgcca atctgtagga
    15421 tatcgctgta ctcagccacc atatcgatat gcccttcatc catcacttca gtaatcactt
    15481 tcattccaaa ttcatcagcc gcttgacgga tgtatttcaa tccttcttct tctaaacctt
    15541 ggaaagcata tggagaagta cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc
    15601 cggctttggc cattcgcgca cattctctga tttggtctaa tccttcgata gaacaaggac
    15661 cagccatcgt cacgaaactg ccgtcaccaa tttttactcc gtctacatcc acgactgtat
    15721 tgccaggatg gaattctcga gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt
    15781 ctactccttc atagcgtgta aatgctcctt cttgtaaact tcgcgtatca ccttttagtc
    15841 caatcactac tcgttctgtt ccttgatcga ttgagacttt gaatccttct ttttcgatat
    15901 gatcgacgac tttttttatt tgttcttccg ttgcttcttt tttcataatt actatcattg
    15961 tttttcccgc tttcttttgt ttacttatct atcttggctg attttctcta ctttttcaag
    16021 gtggttttac attaattcct actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt
    16081 ctttcctact tatgacccag ataatcaaca aaaaaagatg tccctgtagg aaattgcctc
    16141 tacagtgaac atcttcaacg agccttaaaa agcgctgcaa aaatataaaa tagccactat
    16201 agatgaattt ctctacgtgg ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac
    16261 aaacctggtt tgtttgtacc cacgaagtca tgaatacaaa cctatctaaa atagctaaag
    16321 taatacgtat tcagttttgt aagttttcta gatttcataa aaaatcgctc caaactgatg
    16381 taagaattgt acctagtata gacataaaaa aatcgactgt caatcatttt tatgaaactt
    16441 tttttaattt tctgatagtt aactttgttt ttcagaaaaa taacaattgg ttttattgaa
    16501 gaaaatagtc atgaacaaaa gtatctgaga acttttttac tctcttgttc atgacatata
    16561 gaataaagca gctttgtctt gtaaactccg tttttcaaat aataatctaa agattgctac
    16621 tgaataataa agccgatttc atggtcctct tcgctgctga ttcggtaagg tgactcaaca
    16681 tccgctcccc agctattgat acccccgact cctcttactt ttgcaaaaat cgtaagaacc
    16741 gttcgtcttt ctggcggtag ttcttctata tgtgttgcct gttccagttc ttctgctttg
    16801 aatggtaaag cggaaaaagc aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct
    16861 tcttgatctt tatccgtatt atccaacgtt tgatttcttg ttagttctac ccatttcgtt
    16921 tccatatgca tgccgcattc ttggggaaca aggtatgggg aaacggggag tcctgccact
    16981 ttataaatac cttcgacacc accagccatc cgatccggat atgtttcccc tgataggcct
    17041 tcatactcaa aaaattttgc tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat
    17101 tccggtaatc ctttttgtcc ataataatgc atattgacaa gcattttacc ctctccagcg
    17161 atttggtagg aaattgtcac ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg
    17221 atttcaaccg tttcagcgta ttcattactt gaatattgat tatttactgg agcaatcggc
    17281 aaatcgatct ttttattgtc caccagtact tctatttctt tgacttttgg atacaatccg
    17341 gctcctaacc acataccgga tttaaatcca aatccgctac ctctgtcatt atcggtcgtt
    17401 gctcgccaaa aaactggaag tgtttcccgg tatagccatt cttttccgtt tttattgagc
    17461 gattccagtc cgcctcttgt ataagaaaaa atataatgcg tattccccga tttgacacct
    17521 aatgtacagt cgccgaagac gattgcaact ttttccgtat ccatatgact tttatttact
    17581 gtatttttca taataatatc ttacctcctg catggcgggt ttttcttgtc catctgcaaa
    17641 aacgatccca ttccctgaga attcatagtc acttggttta tcgtcaaagt caccgccata
    17701 gcgcatcact tctctgcctg tgattggatc agtcacttgg atcgcctgat ctttaaaatc
    17761 ccatatatag cctccttggt acatttcata acgatcaagc aacgtcatgt aagaatccat
    17821 tccacctaac gaattcccca tgtcatgcat atattcacat aagatgaacg gtttttccgc
    17881 tttattttca aggtagtcaa tgatctcttc tggtggcgca tacatgcagc tttttacatc
    17941 tgaaatcgaa tcttcgaatg ctggatttgg aaaattccct tcataatgga caagtcgatc
    18001 ggggtctact tttttgaagt aatcgttcat ttgtcgaatg ttttcttccg cataagattc
    18061 atttccaaga gaccaaaaaa gaatacttgg atggtttttt aatgtttcga aattcgtttt
    18121 tgctcgatca agaacagccg cctgccactg aggtactgca cctggtacgt tgtaagaagg
    18181 ctcaaatgcg cccatttttt gccatgagcc atgggattcg aggttcgttt ccgccatcac
    18241 atggattcct gcttggtcgc ataaataata ccaagtgatc tggttggggt aatgagatgt
    18301 ccgtacgccg ttgatctttg cattttttat gatagccaaa tctttttcca tatcttctat
    18361 agtgatggcg cgtccttttt tcggatgcca ctcatgtcga tttaccccgt tgataatcat
    18421 ccgttttcca ttgaagtaga tgattttatc tttgatttcg attttacgaa aaccgaagga
    18481 atagtcaata tactccgtta ctcttttttc ttcgtctatc gtctccaatt caagcttata
    18541 taaattgggc tgaaaatgcc cccacagtgc cacattttca aatccatcga tgcgaatcgt
    18601 catttgctct tttaacggat attgctgttg atagatttcc ttcccatcag gatctagtat
    18661 cgctacattc agctgactgt ttttggctac ttgctcaaaa gacaaatcta cttcaagttt
    18721 gccattttga catttgtcat ctaagcgagg tttgatccaa agatcttcta aatggttttg
    18781 tcctcgagca actaagaaga catctctgaa gatcccaaaa aatcggaaaa agtcctgatc
    18841 ttccaagaat gcagctgtac ttcttttgta aacctccaca gctagaatat tttcttcttc
    18901 caaataaggt gttaaatcaa attcagacgg agtgaacgaa tcttcggcat acccgataaa
    18961 atgaccattc aaccaaataa acattgcttg ttctacacca gcaaaatgaa tcgagatttg
    19021 ttttcccttt agaccttctt ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc
    19081 tttagcagct gaaaagatcc cttccgcctc tttctcaggg cttgtcgtga aagggggacg
    19141 gcgaaataca tgtccctccc acggatacat cgtattgatg taatggatct tgtcataatt
    19201 tgctaattca atatgactag gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt
    19261 tttataaaat gtttttggtc gtaccgaagg atttggcgaa taacaaaaac gccatgatcc
    19321 atttaaagac tgtttaaggg aggatgtggt ttctacttct tcccttgttg cataacaaac
    19381 atgatcgcta tgtgcatttg attggttcac tctaaaaact tgtggatcat ctaaccattt
    19441 tatatttgct ttcatacttt tttccttctc tctcataact ttttgaaatg aagcagttct
    19501 gtttggaaat caccttgaaa atcggggaag taaagtccaa ctgtcatcaa ttcggccccc
    19561 gaaaatatcc gcttcgaggt ctgttcctga taaagtgcct catcatctaa ccccatcaga
    19621 tatacttcat ggaacgctgg ttgagctgaa gctagtatcc tccctaaaaa cacaatagct
    19681 tcatcttgtt taggagacac aaacatccat gcggcaatat tttcttcaaa aggactcgcc
    19741 aaacgataat aatggccata ctggatcacc ggacgaatcg tttgatagga tataatttgg
    19801 tcttttactt gctttttttc ttcaggagac agctttgtca aatccagttc ataaccaaaa
    19861 acagcgctca tagctgtttc tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga
    19921 tttggtacag ctgatacatg agctgtgatg gacgaaatcg gataagcaag gcttgttcca
    19981 tattggattt tcatacgctc cactgcatcc gtgttatcac ttgtccatga ctgcggcata
    20041 taataaataa acccggcatc aaaccgtcca cctccaccag aacagccttc ccataagatt
    20101 tccggataat cagttgtcaa atgttcaagt agttcataaa gcccgagcat ataacgatgc
    20161 gctacttctc cttgtctctg tgggtcaagg gtaatcgaat agacatctga aagcgaacgg
    20221 ttcatatccc atttgatgta gtcaagagga atcgtatcta aaatctttct catttgtttc
    20281 tcaatcgtct gccgaacatc taaccttgta aaatccagta catgttgtga tctggaagca
    20341 gaaggcattc tacctggctc ctgcataaga aaatcaggat gtgttcgata cagttcagaa
    20401 tcaaccgaga tcatttcagg ttcaaaccat aaaccaaatt tcaatccttt gctatgagca
    20461 taatctgcta tttcacgtaa tccatttgtc aacttgcctt catactcgaa ccagtctcct
    20521 aatgaagaat tgtccgcatc tctttttcca aaccagccat catctaatac gaacatttcg
    20581 atgcctagct cctttgcttc atcaatgatc gccttgattt tttcactatt gaagtcaaag
    20641 taagtggctt cccagttatt gaccagaatc ggccgttcag caaattgatg acgacctctt
    20701 gcgattcttt cacgtagcaa ctcatggtgg atctgactca ttttgttcaa tccctgactt
    20761 gagtaagaaa ggatcatttc aggtgtttga aaagactggc ctgcattcaa ttcccacgaa
    20821 aaacgatggc tgttgatccc accgacgact ctcaattgat tgatctgatc tttttcaagt
    20881 tcgaaagaat ggttgccgga ataaacaaat tgaagtccga tcgcttctcc agtattttct
    20941 gtcgtatgat gatgaactaa agcaataaag ttattcatat ggtgactgct cgttcctcga
    21001 cggctttcaa atacttttgt tccagataaa acagattgcc gtgaaatctg tctttcattg
    21061 acatgtgctc ctggcaaagc aatgacttca tcaaatcgcc tagtatgggc aaagtctagc
    21121 tggaaactag ccgctttttc tagtttgatt gtttctccgg tttcatttct tatctttaca
    21181 gatcgtgtga tcactgctct atcagtaaat atggtataga acaaatcgaa ataaatcgct
    21241 gtttctctat ccttaagtga aatcaccaac gtttgtgcct ctgacttgtc catcacataa
    21301 gtttgaggca agccttcgat ctctggcttc ccatctgtaa tataatggct gtcatatctc
    21361 agatccagta agtctgatcc attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc
    21421 atgctgccat gagaagagta ttcttgcggt agtgtatctt tcgacagaga ccggtcagga
    21481 tttaagggaa catttcctga aaatccacga tctcttcggg gataattttt attgtctttg
    21541 tactgcttga ctggtttgcc aaaataaata tgcgccaata cattgctttc ttctatcttt
    21601 atcagataag aaagaaatgt atttcgtaaa tggaagactc ggctcttttc atcaaataag
    21661 atgaaatttt tatctgtttt tctatgcgta atatccatca tttcactccc aacaaaacgg
    21721 aaaccgttta ctttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgtg
    22861 aaaagccgct tcgtttcttc atactcaaaa cgaaacggct ttttcacaac ctcttactta
    22921 tacttattca caaaatccaa tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa
    22981 tcaaattggt attcatgggt aatctctttt tttgtatctg tataaaacaa ggattgcacg
    23041 ggtaccttta attctgtcaa ccgattttct aatgcttgac cttgctcctg gaatgagtat
    23101 gcatttccgt cagttatata cgttggcgga aattccttag aaacatggtc agccacacta
    23161 gcttctttca attgctcact cgttttccaa tcttttgttc caatcaacga ccacgcaacg
    23221 gttttgacga aaaacttcat aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa
    23281 tcaacaggtc cgcaataaga aatggttcct ttcagactat cttttggaag tagctgtttg
    23341 attttcattt gtttagcata cgcatcattc gtttgtatag ctgcatattg caatgcgatt
    23401 tgtgaacctg cactatctcc accaaaaaat aattgttcca tgtctagcaa tttgtcgtct
    23461 ttttcttcag ctaataaatc tttgatcagt tcattcactt gaagaacttg attagggtat
    23521 tctgaatcag gcgctaattc ataattcatc gcaaccactg cgatgttggc gtctgaaact
    23581 aattttgtcg caaattcttt gacacccgat ttatctccgc cgacgaatcc tccaccatgt
    23641 acccaaaata gaacaggaac aggccccttg ctgttttttg gatagtagat gtcataagta
    23701 ttctctttat acttggactc atacgtcaaa tctgtttttt tcgccacgtt tttttctgct
    23761 tgatcgaacg tttttttatc agtgatttga acagtatttg aaaacatatg gttgatcaag
    23821 aatgctccag gtctggggga aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga
    23881 atgattccga agaaccatcc gataaattta agaattttct ttttcataag gctccctcag
    23941 tagttagtat taagcattct gattatacca tagtgttatt tcctatcaag ctctcctaga
    24001 tgatttaatg attttcccca aacttcttct gcaatgcttt tgacaaaaga aattttttcc
    24061 attgttcttc aaacaaaaca ttttcttctt ctgttgaagc aaatccacat tgaggactta
    24121 agcacaaacg atccaaaggc agatatcgtg tcgcttcgta gatccggtca atcacttgct
    24181 ggtgctcttc catttcgcca tttttcgtta cagtcaaaat ctaagacaac taatttatct
    24241 tcagagactt tctctaaaag aacaaaactc ccagcacgtt cactatcgta ttctaaataa
    24301 taggcacgga cattttcttg agtaaaataa tgggtctgct acgtcgtcat cccccctgat
    24361 gccgccaaaa tcgaataata atttccgcgt caaacatgta tatttagtgt tgaatcattt
    24421 gagaatatga aaataaaaat ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa
    24481 atctgagaca gaatgacgtt cattctgacc cagatttgat tttgcacaac tcaacagtcc
    24541 ttattggcaa atcgccaaaa taatgtagac taactaaaa
//
LOCUS       DAIGTA010000043        24395 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.043, whole genome shotgun sequence.
ACCESSION   DAIGTA010000043 DAIGTA010000000
VERSION     DAIGTA010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.043"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            115..696
                     /locus_tag="NOB43_001842"
                     /pseudo
     CDS             115..696
                     /locus_tag="NOB43_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
     gene            700..1341
                     /locus_tag="NOB43_001843"
     CDS             700..1341
                     /locus_tag="NOB43_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982697.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1338..2255
                     /locus_tag="NOB43_001844"
     CDS             1338..2255
                     /locus_tag="NOB43_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0982698.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2252..2923
                     /locus_tag="NOB43_001845"
     CDS             2252..2923
                     /locus_tag="NOB43_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982699.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3464..3952)
                     /locus_tag="NOB43_001846"
     CDS             complement(3464..3952)
                     /locus_tag="NOB43_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HCI0982700.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4153..4419)
                     /locus_tag="NOB43_001847"
     CDS             complement(4153..4419)
                     /locus_tag="NOB43_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI0982701.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4419..4682)
                     /locus_tag="NOB43_001848"
     CDS             complement(4419..4682)
                     /locus_tag="NOB43_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0982702.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5158..5343
                     /locus_tag="NOB43_001849"
     CDS             5158..5343
                     /locus_tag="NOB43_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0982703.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5485..7308)
                     /locus_tag="NOB43_001850"
     CDS             complement(5485..7308)
                     /locus_tag="NOB43_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCI0982704.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7906..10611)
                     /locus_tag="NOB43_001851"
     CDS             complement(7906..10611)
                     /locus_tag="NOB43_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HCI0982705.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10917..11864)
                     /locus_tag="NOB43_001852"
     CDS             complement(10917..11864)
                     /locus_tag="NOB43_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCI0982706.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            12054..12323
                     /gene="rpsN"
                     /locus_tag="NOB43_001853"
     CDS             12054..12323
                     /gene="rpsN"
                     /locus_tag="NOB43_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCI0982707.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12499..12861)
                     /locus_tag="NOB43_001854"
     CDS             complement(12499..12861)
                     /locus_tag="NOB43_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0982708.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12872..13993)
                     /locus_tag="NOB43_001855"
     CDS             complement(12872..13993)
                     /locus_tag="NOB43_001855"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCI0982709.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(14009..14359)
                     /locus_tag="NOB43_001856"
     CDS             complement(14009..14359)
                     /locus_tag="NOB43_001856"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCI0982710.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14489..16000)
                     /locus_tag="NOB43_001857"
     CDS             complement(14489..16000)
                     /locus_tag="NOB43_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0982711.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16322..17674)
                     /locus_tag="NOB43_001858"
     CDS             complement(16322..17674)
                     /locus_tag="NOB43_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCI0982712.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17827..18903)
                     /locus_tag="NOB43_001859"
     CDS             complement(17827..18903)
                     /locus_tag="NOB43_001859"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCI0982713.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            19099..20844
                     /locus_tag="NOB43_001860"
     CDS             19099..20844
                     /locus_tag="NOB43_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HCI0982714.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21124..21561)
                     /locus_tag="NOB43_001861"
     CDS             complement(21124..21561)
                     /locus_tag="NOB43_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HCI0982715.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21545..22918)
                     /locus_tag="NOB43_001862"
     CDS             complement(21545..22918)
                     /locus_tag="NOB43_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982716.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAICLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23240..23728)
                     /locus_tag="NOB43_001863"
     CDS             complement(23240..23728)
                     /locus_tag="NOB43_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0982717.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23750..24352)
                     /locus_tag="NOB43_001864"
     CDS             complement(23750..24352)
                     /locus_tag="NOB43_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0982718.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6997 a         5195 c         4512 g         7691 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaactagcaa gccgtatcgc catcatgagt gaaggccgtg tgatccaatt tgatacacca
      181 gaaaatattt tacgtcatcc tgcaaacgat ttcgtagaag agttgattgg agaagatcgc
      241 ctactacaag ccaagccaaa tgcgacaaga gtcggcgaag ttatgctaaa tacagcaatc
      301 acgattacac cggaaaaatc attacaagaa gcaatcaaac tgatgaggga aaaacgtgta
      361 gatacgttgt tagttaccga taattcgaat gtattaaaag gatttatcga tgtagaaacg
      421 ttgaataaaa aacgaggaaa agtatccagt gtcggcgaca ttttgaataa acatgttttt
      481 tacgtaaaag aatccgccta tcttcgtgat accttgcaac gcattttaaa acgcgggctg
      541 aaatacgtgc cggtcgttga tgaacagaac aaagtcgtag gtatcctgac tcgtgcatca
      601 ttagtggata tcgtctacga tgtgatttgg ggagaagatc ccgcaactac tgatgttgca
      661 gagtcagcta ctcctgaaga atctaaggag gtctgaccta tgcagcagtt ttttcatcag
      721 cacggttcag aaattctctc aaaaggtttt gaacatcttt atatttcagg acttgctttg
      781 atcattggta tcatcattgc tgtaccgctt ggtgtcttac tgacacgttt tccaaaagct
      841 gccacgattg tgattggctt aaccagtgcc ttgcagacaa tcccttctct tgctttattg
      901 gcattgatga tcccgctatt tggcgtaggt aaattacctg cgattatcgc actctttatt
      961 tattcattat tgccgatttt acgtaatacg tacattggga tgaaaaatgt cgattggaat
     1021 tatcgggatg tggcaaaagg catggggatg actgagttcc aatccatttt ttccgttgaa
     1081 ttgcccattg ctatgccaac gatcatggct ggtattcgtt tagctgccgt ttacgtgatt
     1141 gcatgggcta cacttgcctc ttatatcggc gctggtggtt taggcgattt gatttttagt
     1201 ggactgaata attaccaacc agatctcatt ttggcaggta cgatccctgt aacaatttta
     1261 gcactattgg ctgattggct tctaggtctc ttggaacacc ggctgacacc gatcgcactt
     1321 agagaggaga atgaagaatg aaacgtatac taaaaatgac catggttctt ttctctcttc
     1381 ttatacttgc gagttgttcc ttccctggtc ttgccagcaa tacagatgaa gacaccattt
     1441 cgatcacagg tggaatcact tcagaagcac agatcttagc aagtctagtt gccggaatgg
     1501 ttgaacatta tacagataaa aataccgcaa tcatcaacaa tctggctact acaactatca
     1561 accatcaagc gatgatgaac ggagatgctt caatttcagc ggctcgctac acaggaacag
     1621 atttaacgac tacattgaac cttcctcctg aaaaagatcc gaaaaaagcg tttgctaccg
     1681 tgaaagatga atttgagaaa agatacggtc aaacgtggtt cccgtcctat ggttttgaaa
     1741 atacgtatgt ctttcttgtt cgaaaagaca ccgcacaaaa ataccatcta tctaaagtca
     1801 gcgatctgaa aaatgtagcg gatgaattag tagctggtgt agatacttct tggatcaatc
     1861 gtaaaggaga cggttatgac ggcttccaag aaacttatgg cttctccttc aattcgatat
     1921 tacctatgca gattggactt gtttatgacg cagtcgaagc aggaaaaatg gatattgttc
     1981 ttggctactc tacggatgga cggatcgcca gttatgatct agtcatgttg gaagatgatc
     2041 gtcaattctt cccaccatat gatgctgctc cagttgtaga caacaagata ttagctgata
     2101 cgcctcattt aaaagaagcc ttaaataagt taggtcatac catcagtacg gaaaaaatgc
     2161 aggaattgaa ctacgaagca gataataatc tagtggaacc atcagtagta gcacaacgtt
     2221 tcttacaaga aaaccactat tttgaaggga agtgaagcaa ttggataaaa tgaatgtctt
     2281 tcaacaattt ttctattatt tccaggaaaa tggctcctat atctttgcac aatttatccg
     2341 tcacttcctg atttctatct atggtgtcct ctttgcagca gttgtcggga ttccggttgg
     2401 gatcatgatt tctaggagac gtaaattagc aaactgggtg attcgtttgg cgaatatcat
     2461 ccagacgatc ccttctctag ccatgatctc cattttaatc attggattag gcctgggagt
     2521 caatgtcgtg attgttactg tatttttgta ttccctctta ccgatcatca agaatacgta
     2581 taccgggatg atccaagtag acaaaaacat ccttgatgtc ggcaaaggca tggggatgac
     2641 tgctagacaa cgactattca tggtagagtt accactctct gtttctgtta tcatggcagg
     2701 cataagaaac gcgttagttg ttgccatcgg gataaccgcg atcggtgcat tcgtcggtgc
     2761 tggtggtctt ggagatatca ttatccgagg aaccaatgca acagagggca catcgattat
     2821 tttagcaggt gcattgccaa ctgcattaat ggcgatcatc acggactggc ttttaggtat
     2881 tttggaaaga cggctagatc cagccagccg tacatcacgc tgatgttatt gtaaaaaaca
     2941 aaagcttctg cgaccatttg ttggtcgcaa aggctttttt agttctgtca tttttaaggc
     3001 aataatccac tctgattctt ccctccttat gggcaaagag ttgcttttct tagctattta
     3061 tccattccgt atactccaac ttcatactgc caacgggttc atatctgcat ccaccgacta
     3121 agtttttttc ttatccgcta aggcattttg ccaatccatt ttcccatcac tcgtcatgga
     3181 attcatacca catgatctct aaatactcgt ctgcttgttc tttgaattgg gcatcaattc
     3241 ttacatcctt tggcgtggct ttcatttaag ccttttccat cagtcctcga ttgttcgatg
     3301 ccttcagctg catcatcaaa actggtgact gccgtatcgg taacttcgat catcttttat
     3361 acaatcggga acttgccatc ctcatccttg gctaaaaaca tatctagcca ttccagcttc
     3421 tcgccatggg aggtttgcgg ttcctaaaac cggtacacga ttcttatgga ctgcatccgt
     3481 cgcaactaga cttggcgata cgatgatcct tcaccagaag agcacccccg taaaccaatt
     3541 gatcgatata ttgccaataa gaaaagacat tggcgtaaaa gatatcgatc cctcgtgatg
     3601 cattgccgtt gatactgcta ttcatggccg aaagcgccac gactttaact tcttccgttt
     3661 gagtgacatt catgttcggc aatgtcgctt tggatacccg ctctgctaaa ggaacgacac
     3721 tggtattgta tttcgtatct gtatcttttc caaaagacca tgccaacgaa tcctctggga
     3781 accaataaga cgactccggt tgattgtcca ttgctttttt caacatactt ttggctgttt
     3841 ctcgataaac gacatttcca attgtcttcg cctcactttg gcgataatcg atggtcgttg
     3901 ccactgccaa cactaacaac gatgctccaa ttttactgat tttccttgtc acacttcttc
     3961 ctccttgttt tacataaacc cgtcaacatt ccattcctaa actcaaacaa tgacccttca
     4021 aaggtggaga tataggaaca aattaaagaa atcatgcaat aaatccaaga aggttggttt
     4081 tagaacaaaa aaagagtctc ctttttgggg agactctttg ttaactatct aaaaaggttg
     4141 gctcttctca cttcactcat aatgtgtcca ggcagaataa atttctacaa ctttattttc
     4201 ctcatcaact ttgtaaacca ctcgatgctg tctattcagc ctgcgtgagt atctgccttc
     4261 atgtgtaggt ctcagctttt caaaagactg cgtgggcata tatggatctt ccttcaatgt
     4321 ctgaatcact tcttcaaatt gtttctttaa attcgtttgc ttgatttttc ttaaatccac
     4381 tttcgcagag tttttgattg cgactgtata gttactcatc aaagagcttc ccaatcaata
     4441 tcatcgatat tcgtaaagct actgtcgtct ttttcgcggt ctcgtacttt atctaaagta
     4501 cctgtttgct caagaaaaag ggtttcttga atcgctctcc agtcttccag cccaatcaat
     4561 acagcattgt ttccactacg atcactaata atctcgattt cagtatgatt ttcatttacc
     4621 tctttcaata actgataaaa atttttacga gcagtgctag gattcatcgt tgtattagcc
     4681 attgtctctc ctcctttttc tgatataatt atagcgtact tgattaagta cgtcaaaaaa
     4741 atacaataaa gcacttaaat tcagcaaact tttcctcttt tttacataga gaaaaagacc
     4801 cctttttagg gaggatcttt gtccacgctc acttcttact cctttacgac tagcggtagc
     4861 caaacgtaaa gtaattggta acaacgtatc atctttagca aaggtcgaat ccaaagcctg
     4921 tgagtctatg caacaacacc aatacacgaa ggttcctcgt tgcagtgtga cttgattgat
     4981 atcttgaata acctgaggat acgcacgaaa gatttgtaac ggttattcaa aactgatttt
     5041 ggccgtcaag tcttctactg cctcaaaaat gattgcctct ttcgtctcct gtcattcatg
     5101 ttcactatcg atttgatact tgcttagacc gttgggtttg tgaatcacca attaaaaatg
     5161 gcactgagtt atggtaacaa aaaatggtca cttgacgagg ctgagattcc tacttatgaa
     5221 gacacatggc acttaagagt cgaggtaaag gaagaagctg aaaatatagg aggctgtaca
     5281 ttatttggca aaggattcgg aaattatgat caagacatca aaatcaaaat gttttacagc
     5341 taaataggaa gaataataac atttcatacg ctgttcccat ctttaatggc ttatagaggg
     5401 cacctttagc tgagaataag acaaaacaga ccctctagct tcaattaaga gctagagggt
     5461 ctgtttttga ttttaaaact tggtttattt cttcaaatgg tagctatagg tgctgacaac
     5521 gatattttca cgccaagaca atcgcaatct taaccgcaaa cttgtttggt tatggagaat
     5581 attctgccag cgtctgtttg gtacaaattg aggaatcaac acagtagttg tatagttttg
     5641 tttcgctgca tttttactta cgatatctac ataacggata attggatttt caatcgagcg
     5701 ataagaagag tggacgattg aaaaacggac atctgggaaa tgctttttaa attctgcttc
     5761 gatttctttt tctttttcga catcttcgtc tagcgaaaca tgcatcgcaa cgacataatc
     5821 accgatcgaa cgtgcgtaat tcaacgcacc gatatttacc cgtgtcacat tcccgactaa
     5881 tacaagaacg gtattcccgt cataatcatg tagttttgca tcattttcta aacgaagctg
     5941 ttctgctact tttttataat gatcatggat cttataaaaa atgaacataa cgattggcat
     6001 aatgatgaag aaaggccaaa tgtcccctaa ccgatagaca aacaaaatcg caatgattgc
     6061 atatgagatg aacgcacccg taatattggc aatcgatttg cttaaccatc tttttccttc
     6121 ttttttccat ttgacgacca tccctgtttg agataaagca aatggaatga acacgccgat
     6181 agagtataac ggaatcaagc gttctgttga gccatggaaa ataaacagca atacgatcga
     6241 acctagcgct agtgtgataa tcccattgga atagcctagt cgatccccac gatcttgata
     6301 catgtgaggc atgaatttat cttttgccag attgtatgca agaactggaa aagcagaaaa
     6361 accggtgtta gcagcaactg ctaaaatcag cgctgtagca aattgaagga cgtaatacaa
     6421 aataccatgt ccaaagacag ctttaccaat ttgagacaaa acagtgactt ctttttcagg
     6481 aacgatccca taccaatagt tgataaatgt gatccccacg aagaagaaac ctaagatcaa
     6541 tgccatcatc gtcaatgtag cagcggcatt ttttgctctt ggcttcttaa agaatggtac
     6601 agcattacta atcgcctcca ccccagttaa agaggaagaa ccagaagaaa atgctcgtaa
     6661 aatcaaagcg atagaaacac ccggcacagc cgctcctgga agtgcagtag cttgcaatgg
     6721 cacagcacct gtcacgatat tatataaacc aacaacgatc agtaacgaga tcacaaggat
     6781 aaatgtgtac accggaaata ataggaacga tgcagattcc ctcagcccac gaagattcag
     6841 catcatcagt agcaaaacga ttgtcacaga aatagcgact tgatgaccgt agagtgctgg
     6901 caccgctgat gtgatcgctt cagcacctgc tgagacagat actgctactg tcaacatgta
     6961 gtcgatcaat aaagagccac cggaaatcaa gccagcattc tttccaagat tctcactgct
     7021 gacgacatat gctcccccgc catgaggata agcatggatg atttgacgat atgatagcgt
     7081 taatgaaatc aataaaataa taacaaaagc ggcaatgggt agcgaatacc agatggctgc
     7141 agcagacaaa gcgactaaaa cgacaacgat ttgttccgta ccatatgcaa tagatgataa
     7201 cgcatcagac gacaataatg ccaaagcagc aaatcgggtt aatttgtgct catcattttc
     7261 agcagatttt aaaggcttac ctactaacaa cctttttaag taatccaatt tctaaactcc
     7321 tttacacaca attttacttc aagttttata gtcgaaaatt tatagtaaac aagatgttat
     7381 agtacgctca ctgaccttaa aagtcaataa actttaagaa aataattgga aaaaaacaga
     7441 aaaatatcaa gcgctttttc aaacgcttta atacagcaaa aatctaacat ttttttatgg
     7501 gctttttctt tgaattctat aataaaagga tagaacttga cttagaaaat caagttctat
     7561 cctttttgat atcttaactt ttggaagaga gatgtaaggc tgctttctac ccatcattct
     7621 tactactcga agcatagcgc agttgtcaca acctcttgat aaacggtgtt taaaagcttg
     7681 catctgcggt aataagctca accaaattaa aaacataaga agctgttttt atttggtcgt
     7741 tcttattact tgatgcagag cagctttttt acaacctctt ggtacacggt gttcaatcag
     7801 ctgaccctcg gtattagctc aaaaaaacgg caaaatatga ggaactattt ttccattttt
     7861 ttctctaata ctcaggtcaa aacactgatt tcacaacctc tttttttaat gaaaaatatg
     7921 gctctcatgc gccgcttctt tgaatttcgt cattttttct tcgatgaacg gatagattgc
     7981 cgttcctacg attccaaaga caacaaacaa accgatcatg atccagattg ctttcgtagc
     8041 atttggccaa taaattcctc ctgcagattc ccgtaacaag tttaccgcat gagtaaatgg
     8101 caagaacgga ttgatcattt ggaagaattt ccctgagact tggatcggat agttcccgcc
     8161 tccgccagag atcgacagta ctaagatgat aatagcgatc cctttaccga cattatcgaa
     8221 taatgcagcc aagacataga cgatcatcat gaacgctaag gcgatcaaga cagcaaatga
     8281 cacgctgtag accggatttt ggacatctac tcctagtaag aaaatattcc ctaatgtaac
     8341 gatcaagctt tgcgcaatcg ccattgtcaa aaatgtcagc atacgagcaa cgaattgttc
     8401 tcgtttcgta aaattgtttc ggtctttctt tcctaaatag tattctgtcg tagcaacact
     8461 tgaaagaaga acagcgccga cccacagaca tagtgcagta taaaacgggg tgctagctga
     8521 accgttattt gcgattggat aaagcgcatt ggtttgtagc tcaacaggtt gtgtaaagaa
     8581 gtcactttct tttgttgcgt ctagtttcaa taatttgatg acttcgccta gatcgacttc
     8641 ttgttcgcct tttcggatcg cgtctgctgc tttttggata ccagctttga tatttggcca
     8701 gtcattgttg atcaagtccg cagcagcgtt cacagctgtt tcgacttctg gcattttttc
     8761 atttactgtt gtcaatgtac cggtgatttc attttttagt gctggccaat cattttggat
     8821 aaaatcagcg gccaatccta atttttgctg aatgatcggt aattcattgt tgtataggtc
     8881 tgccccttca ttgatgccat tgacgatggt atccatattt ccattcagca ttgtattggc
     8941 atcatggatt tcttgtccaa ttgcaggcat ttctttttga tatttttcta aaattgccac
     9001 tgcattcgtt acagttgctt tcgttgagct gagaagcgaa tcaaagtcga tctggtccgc
     9061 tttgctcagt gcgccttgtg cagtcccaat cgtatcgatg acttggtcta gtagagaagt
     9121 gacagtggaa ctgatttgac ctgtattgat accagcaatg atgccattga tattattaac
     9181 aacggcatca atttgatcta gcaattcatc aatagccttc gtgtcttcat tttgaacagc
     9241 tgtgttcaaa gcagataggc ggttttgcag attgcttagc aagggtttta attgatttag
     9301 ctgatcaata attggctgta atttcgtatt tccagcactt gtttgcaatt tagtcaggaa
     9361 ctcgaccagt ttatcgattg cattttgttg ttgagatatt ccgtcaataa agccgttcaa
     9421 tacattgctg atgtttttct tttcatcatc agtcagctta ccatcttcaa tagctgttct
     9481 tacagtatct attaacgaac ctgtcgttgt tgccacttgt ccaattgact tcaatgtaac
     9541 atctacactg tttgtgatgc ttggtatcgc atctttcagc tgagaggcac ctgattttgt
     9601 ttggtttgct agatcacttg cctgattttc taaatttttc acatctggca agatatcttg
     9661 tacttgttgg atgatcgtca agccttgttt tgcttcatcg attccttggt tcattgtctc
     9721 ttggatcgaa gcaaaatcgc cgtcgatctc tgctagttgc ttaccggcat tttggatctc
     9781 tgggattttt tcttgcaaat caaggatgat ttttgcttga tctttcaact caggcatttt
     9841 gtcattcaat gcaacgactt tttcacccat ctcatctact ttagggatgt aatccacgaa
     9901 ttcatttgct ttattcagtt tttccttgat ttcaggtagt tgactttgta attcgaggac
     9961 ttgttttgtg tagccgtcga tcgtgtccaa attttcatct gttgataaaa tcatatcttt
    10021 aactttattg atacttacta ggttcgtatc gatgtcgtaa cctatctcat tgaatacttt
    10081 caataaagtc gaactggctg ttttgataaa ttcatttgtg atttgcgatt ggatcgaact
    10141 tgctccttta tcggtgattt tcggtgcaat cgcattgatt ttttcattta ccgtatattc
    10201 gatttttggt ttcttgatat caccactagt aaaactcagc agatcttctg agaaatcctt
    10261 tggcaagtaa atacctgcgt aatactttcc ggaacggact ccgtcttcta attgttcttt
    10321 tgaatcaacg aattgccatc ctaattgttt atttttatga agcgattcga tgacttgctc
    10381 cccaatggcc acttctttac cttgaaactc tgctggcttg tctgcactgt aaacagcaat
    10441 tggcagctct ccagtatttc catatggatc ccataatgct ttgatgttaa accacgcata
    10501 tagcgaaggg atgatcatga tcgcgatgat cagaagtgtt gcaatcgggt ttttgaaaat
    10561 ccgtttccag tcaagcaaat ataatcgaag cgtatttttg attgactgca tagttctccc
    10621 ccttcttctt ttttcagctg aattacttta ccatgtattt catacttttt tcaatcggct
    10681 tttttcaaaa aagtcgaatt tttggacata tcacggcaat tgtctcattg taatctctta
    10741 catattgaga aataattaag gattacagcc tttactttat catgaaataa aagggaaaga
    10801 taattttatg ccaaagtttt tatctattat acgtatacgc aaaaaagcta aaacattttt
    10861 tgtctttgcc cctacaaaaa tgtttcagct tttttcgttt tttattcctg tatttcttat
    10921 ttttcgaatg acaggatgat tttcccagca ggaggatgtc cttcaactag ctgatgtgct
    10981 tggatgacat gcttaagtga agcagacaga ttcattgaaa taaaaacatg aaaggctcct
    11041 ttttggtagg ctttgattat gccagcaaag gcttctgcat ctagatattc ctttcttgga
    11101 acaaacgatt cataaaagcc ttcctttttt tgccgcaaat ctagatctgg gaggtcattt
    11161 aatgcaacat acctgccgcc tggtttcatg atctggatgc cggtttctcc tttgatactt
    11221 cctttcgtcg catcgattac aaggtctgcc tgatcagcaa attgcagacc tggatttgtt
    11281 ttatcataag cagcaaatgc tgaagctcct aattttttta ccttttcctc atttttactg
    11341 gatgcactgg ttaagattcg gattcccttt tcatggagaa gctggatcag acttgacccg
    11401 accgcacctg atgctcctag tatcattaca gtatctgtcg gctggatttc cgtcaaatgg
    11461 ttgattagat tataagccgt aattcctggc gtgaccattc cggctgcttc ttcccaactc
    11521 attttatctg gaatttttgc tacttttgct gatggcaaca cgacttcttc tccgtaagtc
    11581 ccgccgactg catggacagc tactcgatca cctacatgaa cagttgtgac atctgaacca
    11641 atctctgtca caataccagc gccatcatta cctggtacat aagggaattt caatgttcgt
    11701 atctctttca tttctcctaa acgcaaggca acatcataag gattcacact gaatgctttt
    11761 atttctacac gaacatgtcc agaaccgact tctctgggat gagcatcgat ttcttcaaaa
    11821 acatcttgtg cttctccgta accgttaatt gcaaatcttc gcatggtcac catctccctt
    11881 tttctttaag tttacgttta tgtctttatt ttgacaaaaa aaatgtcttt tcgttttggc
    11941 gcatgattca aaacaaaata gttgtctttt ttcgcgtaac gtgttaaatt atttatctaa
    12001 aagcgtaaag attacgattt acgctaataa aaaataattg gaggaatttg ttgatggcta
    12061 aaaaatcaaa gattgccaaa gcaaaaaaac agcaagaaac gattgaacgc tatgctgctt
    12121 tacgccagga attaaaagcg caaaaagatt acgaaggctt gcgtaaactt cctttagatg
    12181 ctcgtccaga acgattgaaa aatcgtgatt taatcgatgg acgccctcgc ggatacatgc
    12241 gtaaattcgg gatgtcccgt ataaaattcc gtgaattagc acataaaggt ttgattccag
    12301 gagtaaaaaa agccagctgg taatccaagt ctggctgtaa tgtaaaggag gagggcgcat
    12361 ggaccactcc ttggatcatc aaaaaagata cgttcgcttc ttctagcaga aatgctggta
    12421 ctagaagcag acgtatcttt ttttacgcac agctggtcct tttttatatg taaaggctgc
    12481 atggttactt cgctatattt atttagtaac aggagtcagt gcttcgatac ccacactaat
    12541 tttcaatgct cggtcaactt ctgccataat gggtcgatcc aaatggcaga ccttttcttt
    12601 caatcttgat ttatcgatcg ttctgatctg ctccaacagg ataacggagt ctctttctat
    12661 tcctgttcca gtagctttga tcccaatgtg agtcggaagc ttaggtttag ccatttttgc
    12721 cgttatggcc gcaacaatga tcgtcgggct aaaatggtta cctagattat tttgaataac
    12781 caaaactggg cgtgttccgc cttgctccga tcccacgact ggagaaagat cagcaaaata
    12841 aatatctcct ctttttacca taggatcctc cttattcttg atattctctt ggtatccgct
    12901 gtcctaatcc gcaagccact tcatagtgga tcgtacctaa ttgatctgct atatcctgca
    12961 tagtgatttc tttgtctgca tttttgccga taagcgtcac ttttgttccg acaggaaatt
    13021 cttgaggcaa tcggatcatc agttgatcca tacatacacg cccaatcgtt tcacagtagt
    13081 tcccttctac caatagagaa aaaccctgca tctttcgtgg ccagccatct gcataaccga
    13141 tcggtatcgt tccgatccac tctgcttcag gagtgatata tgtttctcca tagccgattc
    13201 cttcacctgc tgggagtttt ttgacttgaa tcaattcaga aaccagctca agtgctggct
    13261 gcaatggata aacttccggt agtgcgtgcc cagagggatt aagtccgtac attgctactc
    13321 cataacgaat catattgccg attgtttcat catgccataa agccgttgca ctattgctga
    13381 catgtacata tcgaggaagt tcgggaagtt ttttcagcac ttctataaag cgttcttttt
    13441 gcagattcca atatgtatca tctgcctgat ctgctgtaga aaaatgggta aataaacctt
    13501 cccattctaa tacacgactt tctttgatga atgcagctgc ctcttttact tcttcaggtg
    13561 tacaaaatcc gatacgaccc atcccagtgt ctgcttttag atgaatcgaa agaggcgtct
    13621 ctagcttact tttctctaaa acagcagctg ctgcttgcaa ccattcccgt gtacctgcag
    13681 ttactgataa atcatgagca acagctacag tcagtgcgtc gtaaggaacc atattcaaga
    13741 taaggatggg ctgagtaaat ccagcttctc tcaactcgac tccttcatct aaatttgaaa
    13801 cacaaaagcc cgaagctcca cctgcaactg ctgcctcagc tgtttcaata gctccatgac
    13861 cgtatccgtt cgcttttact actgcaaaca attcttttcc ttgcggaagt cttgcaactt
    13921 catttgctac attttcagtt atagcttttt tatgtatcac tgctttcgtt gggcggtgcc
    13981 aagcgacaac catcgttttt ccttctttct agtcttccaa aataatttgt gcaaaagctg
    14041 tttcatttgt atgagtaata ctgacccata cattgccttc atgaggtgaa cgcgtcacaa
    14101 caggctgacc attttcattt tttaaaatct cgacatcttg aaaggtaact tttccgatcc
    14161 cagttcccca agctttagag aaagcctctt tgcaagcgta acgcccgcct aaaaattcta
    14221 cttggcgatg aaaaggcaag gactggaata gtttcatttc atcagaggtc aagattcgtg
    14281 caatgaattt tggtttttct tcgatcagcc gagtgatcct aggaagttcg actgcatcga
    14341 tcccaattcc ttttatcata tgcttttctc ttttcaataa atttagaaca ctctcattct
    14401 accaaattat aaccattttg ccacaaataa gtccacaaat aacaaaaatg aaagtttctc
    14461 ttaaaaaaga gaaactttca ttttatgttt aatcgttatt tgaacggatt acaaatccgc
    14521 gttttttatc attgtgacgt ttaccgccat ctttttggct gttattattt ttgctataac
    14581 cgccttttga tttgtttcca cgataattac cgccgtcacg acgattacgg ttgtttccgc
    14641 caccacgttt gccattttta ttgtatcctt ttttctgcat tggcaatggg cgttctggtg
    14701 tgatcttcac tggcactgca tcagctggat cttttgctgt cgtttttagc aaaagtgcaa
    14761 ctaaatcttg tgcagaatat tcttctaata atttatctgc tgtttgcagg tatttatcta
    14821 gaccattttc tgcaagtttt gtttcgattt gttcaactgc agcacctaat tgacctttga
    14881 atgcttcttt ttcggttggt ggacgtaaag tcgtcatccg ttttttcgtc aagttttcaa
    14941 tcacatgcaa gtagtccatt tcatttggtg taacgaaagt cacagacata ccgccttttc
    15001 cggcacggcc tgtacgtccg atacggtgaa cgtagctttc tggatcttga gggatatcat
    15061 agttgtacac atgagtgaca cctgaaatat ctaatccacg tgcagcaacg tctgtcgcta
    15121 caaggatatc taaatgaccg ctcttaaatg aacgcaatac gctcattcgt ttttgttgag
    15181 acaaatcgcc atggattcct tctgcacggt aaccgcgtgc ttctaatccg cgtgccaatt
    15241 cgtctacacg gcgttttgta cgtccgaaga cgattgttaa ttcaggtgtt tgaacatcaa
    15301 acaagcgagt catgatatcg aatttttcgt attcttttgc gcggacatag tattgatcga
    15361 tcaagtcagc tgtcatttct ttcgctttga tcttcacatg atgtggattt ttcatgaatt
    15421 taacgccaat attcttgata gctggcggca tcgttgctga gaaaagtaat gtttgtcttt
    15481 gatcaggaac ttgtgaaatg attttttcga tatcttccaa gaagcccata ttcaacattt
    15541 catctgcttc atccaaaact aatgtttgaa cggttccaag tttcaatgtg tggcggttaa
    15601 tgtggtcaag catacgtcct ggtgtaccca caacgatatg tggacgatct ttcaagccac
    15661 ggatctgacg gccaatatct gctccgccgt aaacggcttg tacacgtact tttttgtcgc
    15721 gccctaaacg atataattct tcttgtgttt ggatagctaa ttcacgtgtt ggtgcgataa
    15781 ctaaaccttg taattcgtga cgatctggat cgattttttc taacattggt aatccaaatg
    15841 cagctgtttt ccctgtacct gtctgtgctt gtccaataac gtcttttcca gctaatgcta
    15901 gtggaatcgt ttctgcttgg ataggcgttg cttcttcaaa accagcgcgt tcgactgatt
    15961 tcaacaattc tggtgataat tctagttctt taaatttcaa atgaatcctc ctatatggtt
    16021 gttaactgag gatgtagctt ttttgctacc ccgtcgattt gttcggtcaa agtgtattgt
    16081 ttctttttga cagtggccac gcacgttttt atccattctt agcccctgtg gcaccaccga
    16141 aaaatcactt tgcgaagttt aggcattaga aaagccaaac gggtcgcgtt cagctttatc
    16201 attattatga catctggctt caacaagttg tttctatggc aaaaccagtc caatttctct
    16261 tcatctttcg gcaataggtt attctaacat agtttttcgt tttctgcaag tttacagatt
    16321 tttatttcat ttgctgaagt tgttctacca cttcaaataa gcccatgctg ttgctgcctt
    16381 ttagcataat actatctgtt gctgcaagat tttgtttgat agcatcaatc aatttattct
    16441 tttctttttc aaaatagaac acaggtagtt gggggtattt ttggttcaat tcttctttta
    16501 gtgcatgcat ttgttcccca taaaggaaaa tcatggcgaa tttctcagga tcgatatgtt
    16561 cactcatttg cgcatgcata tttaaagact ctttccctaa ttccagcata tctgctaaca
    16621 cagcgattct gcgtcctttt gttggcagat ttttaaaagt atctaatacc agtcccatgg
    16681 ctgttggatt tgcattgtag acatcgctca aaatagctgc accatttcct gccgttagcc
    16741 attcggttct gttttgagtg atagaaacat gggcgagccc ttggcgtatc tcaggtatgg
    16801 acagtccaaa gaagcgcccg atcgtatacg caatcaaagc attcgttaca ttataacttc
    16861 caggcagcgg gatcgtaaat gtttctcctt ctactacaaa atcggtttgt gcttttcctt
    16921 ttgctgtcac ttccgcatga acatcgccat ttccaatacc gaatgttgtg actgtttgta
    16981 ctaatgttgc cgttaaaggt gtcagcaacg gttcatctgc gggcacaacg agtaatccgt
    17041 ctgatacaag tccgtcagtg atttccattt tggctttagc gattccttct cgcgacccaa
    17101 gattttctat gtgtgcttca ccgatcattg tgattgctgc agcttttggt tgagccataa
    17161 gtgaaagttc cgtgatttca ttggcgtgat ccatgcccat ttccaaaacg atcttttctg
    17221 tatcttgggg catgtgcaaa atcgtgtaag gaagaccaat attattgttg taatttcctt
    17281 gcgtcttata tgttttgtat ttttcagaca agacagacgc ggttagatct ttcgtggtgg
    17341 ttttaccatt gcttcctgta attgcaacga cttctgcgcc tactttttcc aagtaatagg
    17401 ttgccaattg ctgcatggct ttcaaaggat ctgctacagg aataactgga aaattttttg
    17461 gagcttgttc aacaggcaag ctccaaaatg aagcagatgc tccgtttgtg atcgcttgct
    17521 ggataaattc atgtccatct cgcgtaccag caagaggaac gaataaactt ccttcggtta
    17581 tcttccggct gtcaaattcg acattggtaa tctttgtcag tgcagagcat tcgctgccca
    17641 cggcttgtgc aatttcttgt attgttagat tcattgagat ctctcctaaa aaaggttgtg
    17701 aaaaaagcgt ttggcctaaa cggcgggttc gcatgactct cacttccaag taaatttctc
    17761 tattcgtatt tagaagctag aatgaacgcg gttacgcaat cactccagcc tcttctttat
    17821 ttctctttat tcattttttt caaaaaaaga ttgacgctga tggtatcgat tcattcctaa
    17881 ctggatcagt tcttcaatca aatcaccgta tttcaagccc atattttccc ataagagtgg
    17941 gtacatactg aactccgtaa atcctggcat agagtttaat tcattcagga ataattcatt
    18001 tttatttgtc aaaaagaaat cgcaccggct caatccgctt ccacctaaca tcgtgtaagc
    18061 taacttcgcg tactcttgcg ctttttgata aacttcttct ggcacttcgg ctggaatctg
    18121 catttcgatt ttattattga tatattttgc ttcataatca tagaatgcta cgtcttttac
    18181 gacttcacca ggcaaagtcg tccgaacgtc ttcatttcct aatacagcaa cttcgatttc
    18241 gcgcgcttca attccttgtt caacgattgc tcgagaatca tactgatagg ctgttgctaa
    18301 agcattttgc agctcttctc ggttttctgc ttttgtaatg ccgacactag aacccatatt
    18361 cgccggtttg acaaacatcg gataaagcaa agaaccttca cattgatcaa atactttttt
    18421 aggattttct ttccattgat tcttaagtac tggtacataa ggaacttgcg gcacaccagc
    18481 agcttgtaaa atatacttgg tcatgatttt atccatggca catgcactgg tcaatacgcc
    18541 tgcgccgaca taaggcatat tcaatgtctc taagaagcct tggatcgttc catcttcccc
    18601 gtttggccca tgtaaaactg gaaaaacgat ggctccttct tctttgattt cgcccggatt
    18661 gatcactttt cctgtaaagc cttcctctgt ctgtccactt gggtcccatg aaagatgcaa
    18721 gacatctttg ctggcaggtt tttctgttag taatggacct ttgacccatt gtccttcttt
    18781 tgtaataaat acgagttgaa cttggtaata attataataa atggcattta aaactgaaaa
    18841 tgcggaaaga atggacactt catgctctgc gctgcgtccg ccatatagta aagtaatctt
    18901 caaaagattg tcctcctgta ttctaaatcg ttcagtgatt tactctcata ttttagcaca
    18961 aaacaaaaat aaacgaataa cttatttata aaaaaacgag ccagcttcta aaagaacgag
    19021 cgtcatttat tttttgtcag ctagattatt tgtcccgttt tttataaaaa gttatgataa
    19081 agaaaaggag ggatgatgat ggcgcaaaca aatccacgca gccgcttggc agaaatcatt
    19141 cgagtgttca tcaattacaa tgtagtgcca aactttgtac agcaaaaaaa tcccgaacag
    19201 gtaaaaaaag cctttgaaga actaggcccc accttcatca agataggaca gatgctttct
    19261 gttcgagaag atttgctttc ttctgccttc actcaaacat tcaaaacatt acaagatagt
    19321 gtacctagcg acacattttc aacggtcaaa aagacgatcg aaacagaact ttctctttca
    19381 ttatcagata tattcgatga tttttcaaaa tcgccttttg cctctgcttc tatggggcag
    19441 gctcatcgtg ccaagctgaa gaacggtgac gcggtagtcg ttaagatcca acaccctaac
    19501 atcgccgaag agatccgact tgatcttcaa ctatttgaac gagcgatccc tttgatcaaa
    19561 tacattcctg aaactagcgt agttgatcta aaaggggtac tccaagaagt aaaacgttcc
    19621 ttgatcaatg aaatggactt cttaaaagaa agtcaaaatg gcgaacaatt ctatcaaaag
    19681 aacaatggct ggaaagagat ccgcagcccc aagatttatg acgctttttg ttcgaaaaaa
    19741 gtgatcgtga tggaagaaat gtctggtaaa aacttgaatc atttaatgaa cgccgaaaac
    19801 aaaactgaaa cttttatcac tggaattcaa aacaagcagc tgaaacaaga agttgcaaag
    19861 cttttagttg agaactttat gaaacaggtg tttgatgatg gttttttcca tgctgatcct
    19921 catccaggga atctgctatt ccatgtacta acaaaagaag aacagacaca agctagccga
    19981 aaaactgaaa cagtccatga aaaagagttc ggttcctttg cttttcgagc ctccacttct
    20041 gcagaagacc ctgttgcgcc atataccatc aactacatcg attttggtat gatggggcat
    20101 ctttctgcag gacttaggca aaaactcaca caagccgttt tagcgctgta tacgaaagat
    20161 gcttatcgaa tcgaaaaagc ggtccttcga ctttgtcagc aagaaggctc gtttgatgaa
    20221 agtcggttcc accaagaact gacaagtttt cttgaacagt attatgattc tcctattgat
    20281 gaaatcaact tgcaagaagt attcacacat gtcgtgacga tttgtcatca aaataatctg
    20341 cagttcgatc gtgatatcac gcttttgctg aaagcatttg ggacattaga aggggtgatc
    20401 cgcgtcctcg atcctgaagt ttccctcatg gaagtcgctt cgccttttgc tcaacattat
    20461 tttctcactc atctggatgt agaagataca ttgaaacaaa gcggattaga cttattggaa
    20521 gggatgaagg ctgcgcctaa gatccctcaa cagctccacc atctattaga aatgtggact
    20581 tcgggacaag gaaaagtcaa tttggaattg aaaaagcaag acaaattatt gagcaggatc
    20641 gaaagtatga tcaatcggct tgttttcggt atgattttag ctgcattgat cgtagggtcc
    20701 tccctgcttg tccaagcagc acctgtagaa aacgcagagg tcgtttcctt attagggata
    20761 tttacgtatg ctattgccgc attcgtcatt atttttttgg caatcgatgc attgatccaa
    20821 atgtataaga agaggaaaaa gtagaaaaag gttgtgacag aaagaatcag cttcaagaaa
    20881 taagaagggg ttttacataa attgtttctc aaatttttgt gaaaattcgg cttatttttc
    20941 gaagaggcta cttctgaaac accgagaata aaaaatgtga aaaagctgtt ctgcacccag
    21001 taataagaac aatcaaaaag ggaacatgga acacatttat cctgtttccc tgttcccttt
    21061 ttgatgtatt cgagcataaa taaaatacct tcgttaccta ctatcttctg tacttggtaa
    21121 accttagtca attgcctttt ttaacgcttg acgaaaagac atatgatctt tctccgtaaa
    21181 gggttttgga ccctttgtcc ttatgccagc ttttcttaac tttccactat gataacgttg
    21241 ttctagaagc gtgccgatat tcgcttcgtc aaattctttt ccagagtgat ggaacactcg
    21301 cacacccttc ggcaatacaa gtgaagctaa accataatct tgcgtgatca aaaagtcatt
    21361 cttcttaacc ataccgacga ttttataatc cgcactatca gctccgcggt ctacgtagac
    21421 gatttggaca tgattagcgt attctttggt cgtataatgg tccacactgg tcacgataac
    21481 cacgtcaaga ccataggatt ctcctaattt tatgacatct tcttttactg gagaaccatc
    21541 tccatcaatg aatagcctca ttctttttcg ccttcttcca taaatgataa acagttacta
    21601 atccgctcag taaaagacca acattgatcc attttgccaa gataagcagt tgtacacttt
    21661 ctatcggcac tgattcatgg ttcagcgtga tcaataatag atggattggc tctcccattt
    21721 cttttgctaa aacaaacaaa agcgtcatca ataaaaactg gtggatcaca ctccctttat
    21781 tttgagtagt atacttgaca acgatccggc gatccattgg aatagctgta tcagtttgat
    21841 aatattcctt atttagccag ctgcctgtta ctacgtgcca gaaactaagc agaaagacac
    21901 ctatcgcaaa accatttgga atcaagagga ccaataaaga agaactcagt ccaagcaatt
    21961 gcatagccaa tggagaccat gttaaacgtt tcaaaatcca tggtccgact atttttgctg
    22021 caatcaagcc tgctgcataa ggcaaataca taaaaatcga aagtttttct aatccgtaca
    22081 gtatgccaac ataaaaactg ctaaataaaa aaaggaaatt ccctagcatt ccatttagaa
    22141 aagtaaacag atttagccag cttggcaact tccattcctt cttctggtgt cctaaaacaa
    22201 acacgaacaa gatgaacagc agcaagaaac cataaatagc aagatcaaaa agcctttcat
    22261 cgaataacaa tcgggcattt ctcaaaagaa acaataagcc aaagaatatc aaaaataaaa
    22321 caagctctcg cgtagctacc agatttcttt tgatgtcttt gaaatccagt tcgtaacgcg
    22381 gataatgact aaccgtatgg taggccatga cgtaaaaaag tgtataaata gtaaagcttg
    22441 ctgcaatctg agtcggtgca ggcaactcaa tcgcttgata caggagaaat aggcagatag
    22501 ctgcaaataa gtactttttc ccatccatat tgataaaacc ttgcgtcttt tcgtgaaaat
    22561 tgaccgtggt attagcaggt acaagccatg ctgcactcag ccctagcaaa acacttgaaa
    22621 aataaaataa aggaaaataa aatacgccta atattccaag caatgaacca gcaccaccaa
    22681 tcagcagagc gatcatcagc aacgtgtaac tatctagacc aaatcgtaga ctgttgacta
    22741 aaaatagtcc agtcatccga aaggcataaa acagcgtaaa tggcaaaatc gtcagccaat
    22801 tatgcgagtc tgttagtccc aaaaataaaa gataaggaat aaaaataacc gtgttactta
    22861 agataaaggg cgttgtttgt gtaaaattac gcccaaatcg tttgagtttt tcgaacatga
    22921 caatggctcc ttaaacagtc ttataactaa tctgctcttc gattttagca ttaaagggga
    22981 aataaaccaa ttttacagaa tatattcttg taaaaaaaaa tacagaaaga agcataagct
    23041 tctttctgca tttttacggt acttgattac tcaagcagac aagcccttct ccacaaaagt
    23101 cttgcccgac acccctgcat ccggcaggtg ataaagatag aaatcaatta tcctgtgcct
    23161 ccaaaatcaa ttaggagctc tgtaaaccag agtccttctc gacccgtcgc ataaatttac
    23221 tttaacacag ttcctatgtt tatgcgagag cttttttcat tttataatcg accatttgaa
    23281 atccttgacc gatatctgaa ataagttctt ctgtaatctc aaatccttca tgcttataaa
    23341 cctcgattgc ttgatgattc ccctgattca ctcgcaaaaa gatctctctt tcctttgttt
    23401 gcgcagcaag ttcttcatac cagcgaaaaa ctgaagaagt caatccttga ccacgtactt
    23461 tatttagcaa atataattta cttaaataaa tttttccatt tatctcttca taagcagtgt
    23521 aaccgacagt cttttcttcg ctttttaata aaaagtagga cacaccttct gtcagttctt
    23581 tttgaatctg tttttttgac tgataagttt tcagcatgta atccacttgt ttttgaccaa
    23641 tgatcggcac aaaagcttcc ggccatactt cttgtatgac tgccatcagc tcatccagtt
    23701 cattttctgt tacttttatt ttttccatac acccacgtcc ttttttacat tataaatgac
    23761 cttgcgcttg atggaataaa aagagcatga tcatgctata cacacccacc gaccatggtt
    23821 tcaagaaaat cacaatctgc ataaattccc taaaagataa tttcgtcaaa ccagctacta
    23881 gacagatcaa gtcgtctggc gcaaagggaa gcagcaaggt aacaactagt acttttttaa
    23941 tatctttcgt ttttcttgtc agcaattcat caaatttctg atactttttt ggcgataaaa
    24001 taagctggac aaaggctacg ccatagtaac ggacaagcaa aaatccgatt gcttccccaa
    24061 tcactaggcc aatacaacta tataaaagcc caaatccatt gccaaacatc agcatgcccg
    24121 ctactgagga gatccctccc ggcaaaatag gaatgatcac ttggatcact tgcaacagaa
    24181 caaatatcat cactgcatac ttgccaaatt gctggataaa cgcttgcaaa gacgtgctcg
    24241 atcgaaaaat cccatgatga taagcataaa gaatcaacac aaagaaaaaa aacagaccaa
    24301 taatgggcat gatctgaaga catttttgta aaactgatcc ttttttagac atctatattc
    24361 cccacatctt ttttcattta ttaaaactgc ctcct
//
LOCUS       DAIGTA010000044        23824 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.044, whole genome shotgun sequence.
ACCESSION   DAIGTA010000044 DAIGTA010000000
VERSION     DAIGTA010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23824
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.044"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(53..787)
                     /locus_tag="NOB43_001865"
     CDS             complement(53..787)
                     /locus_tag="NOB43_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI0982719.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="NOB43_001866"
     CDS             1114..1524
                     /locus_tag="NOB43_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCI0982720.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="NOB43_001867"
     CDS             1517..2218
                     /locus_tag="NOB43_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCI0982721.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="NOB43_001868"
     CDS             2218..3804
                     /locus_tag="NOB43_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982722.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="NOB43_001869"
     CDS             3823..4044
                     /locus_tag="NOB43_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HCI0982723.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="NOB43_001870"
     CDS             4041..4802
                     /locus_tag="NOB43_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HCI0982724.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="NOB43_001871"
     CDS             5182..5691
                     /locus_tag="NOB43_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI0982725.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="NOB43_001872"
     CDS             complement(5766..6305)
                     /locus_tag="NOB43_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HCI0982726.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOB43_001873"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOB43_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCI0982727.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="NOB43_001874"
     CDS             7318..8169
                     /locus_tag="NOB43_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCI0982728.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="NOB43_001875"
     CDS             8197..8832
                     /locus_tag="NOB43_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCI0982729.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="NOB43_001876"
     CDS             8852..9625
                     /locus_tag="NOB43_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0982730.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="NOB43_001877"
     CDS             10033..10830
                     /locus_tag="NOB43_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HCI0982731.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="NOB43_001878"
     CDS             10808..11221
                     /locus_tag="NOB43_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0982732.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13847
                     /gene="mutS"
                     /locus_tag="NOB43_001879"
     CDS             11205..13847
                     /gene="mutS"
                     /locus_tag="NOB43_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI0982733.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAQGYIDALIEKGYKVAICEQVEDPKTTKGMV
                     KREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDEE
                     AVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVDP
                     LEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKKH
                     GTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSALT
                     KVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPMD
                     HLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQETG
                     IKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILEA
                     EEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELVS
                     DKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLALT
                     VLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPNS
                     LILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNVH
                     VGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGHH
                     TVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIESL
                     KQINLLEMTPMDALNTLYELQKQL"
     gene            13865..15973
                     /gene="mutL"
                     /locus_tag="NOB43_001880"
     CDS             13865..15973
                     /gene="mutL"
                     /locus_tag="NOB43_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCI0982734.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15995..16555
                     /gene="maf"
                     /locus_tag="NOB43_001881"
     CDS             15995..16555
                     /gene="maf"
                     /locus_tag="NOB43_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCI0982735.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16640..18628)
                     /gene="treP"
                     /locus_tag="NOB43_001882"
     CDS             complement(16640..18628)
                     /gene="treP"
                     /locus_tag="NOB43_001882"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HCI0982736.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18851..19564
                     /gene="treR"
                     /locus_tag="NOB43_001883"
     CDS             18851..19564
                     /gene="treR"
                     /locus_tag="NOB43_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HCI0982737.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19641..20087
                     /gene="msrB"
                     /locus_tag="NOB43_001884"
     CDS             19641..20087
                     /gene="msrB"
                     /locus_tag="NOB43_001884"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCI0982738.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20257..20859
                     /gene="ruvA"
                     /locus_tag="NOB43_001885"
     CDS             20257..20859
                     /gene="ruvA"
                     /locus_tag="NOB43_001885"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCI0982739.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20872..21873
                     /gene="ruvB"
                     /locus_tag="NOB43_001886"
     CDS             20872..21873
                     /gene="ruvB"
                     /locus_tag="NOB43_001886"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCI0982740.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21902..22480
                     /locus_tag="NOB43_001887"
     CDS             21902..22480
                     /locus_tag="NOB43_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0982741.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22532..23014
                     /locus_tag="NOB43_001888"
     CDS             22532..23014
                     /locus_tag="NOB43_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HCI0982742.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23131..23505
                     /locus_tag="NOB43_001889"
     CDS             23131..23505
                     /locus_tag="NOB43_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982743.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4284 c         5114 g         6646 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca caaggatata tcgatgcctt gattgaaaaa ggctataaag
    11461 tagcgatttg cgagcaggta gaagatccaa agacgactaa agggatggtc aagcgcgaag
    11521 tgatccagct agtcactcct ggtacagtca tggacagcaa aggattgtcg gcaaaagaca
    11581 acaatttttt aacagctgta gttagtcaag gaaatgaatt tggctttgct tatgccgatt
    11641 taagtacggg agaattgaag acggctcggt tgcatgatga agaagctgtt ttaaatgaag
    11701 cctctgcatt gcagacaaaa gaactcgtat taggcagtga gatcactgat acccttcgtg
    11761 aacagctaag cgggcgttta gggctagtct tttctcaaca aaatgagatg gaagaaaacg
    11821 cggaatttag ctttttgaca agcgaactag tcgatccgct ggaaaaagaa gcaaccggca
    11881 aactattgac ttatttatcg gtgacacaaa agcggagttt agctcatatc caaaaagcag
    11941 tagaatacca accagatcat tttttgaaaa tggattatta ttcaaaattc aacctagaat
    12001 taagccaatc tattcggact gggaaaaagc acggcactct tctatggttg ttagatgaaa
    12061 caaaaacagc aatgggtggc cgtttactaa aacaatggct agaccgtccg cttatccagg
    12121 caaaacaaat taaagcaaga caagaaatgg tcgcttcttt gctagacagc tattttgaac
    12181 gtatcgattt gcagtcagca ttaacgaaag tctatgatct ggaacgccta gcaggtcgag
    12241 tagctttcgg taatgtcaat gggcgagact tgatccagct gaaaacttct ttagaacaag
    12301 tgccaatgat cagagggttg attgaaggaa tcgatcaagg tcaatggcaa agtctgcttt
    12361 cagaaatgca gccgatggac catctcgtcc aattgatcga ccaagctatc caagatgatc
    12421 cgccgttaca aataacggaa ggaaacatca tcaaagatgg attcaatgag cagctcgata
    12481 tgtaccgttc tgctatgaga aacggaaaga aatggttggc agaacttgaa gcaaaagagc
    12541 gtcaagaaac aggaatcaag aacttaaaaa tcggatttaa ccgcgttttc ggttattata
    12601 tagaaattac aaaagcaaat cttggaaatg cagaactgga gaagtatgaa cgaaaacaaa
    12661 ctttagcaaa tgcagagcgt ttcatcacac cagaactaaa agaattggag acacaaatcc
    12721 tcgaagcaga agaaaaatct gttgatttag aatatcagtt gtttttagct gtgagagaag
    12781 aagtcaaaaa ggctatccag ccgctacaag tacttgcaaa agcaatcagt gcagtagatg
    12841 tgctacaaag ttttgcaacg atcagcgaac gctatcagta tgttcggcca gaacttgtca
    12901 gtgacaagca tcagcttctg atcaaagacg gacgacatcc tgtagtagaa aaagtattag
    12961 gacatcagga atatatccct aacagcgtag aaatggcaga agacgaaatg atcttgctga
    13021 ttacaggacc gaatatgtct ggtaaaagta cgtatatgcg acagttggca ttaactgttc
    13081 tgatggcgca aatgggctgt ttcgttccgg caaaacaagc agttttacct atttttgatc
    13141 ggatttttac ccgaattggt gcaagtgacg acttaattgc tggacaaagt acttttatgg
    13201 tagagatgat ggaagccaat caagccctgc gttatgctac gccaaacagt ttgattttgt
    13261 ttgacgaact agggcgagga acagcaacct atgacggaat ggcgttggcc caagcaatca
    13321 tcgaatatat ccatcgtcat gtacaagcaa aaacactctt ttctactcat tatcatgaac
    13381 tgacggtact tgagaaagaa cttccgcagc ttaaaaatgt ccatgttgga gccgttgaaa
    13441 aagacggaga agttgtcttc ttgcataaaa tgatggatgg acctgcggat aaaagctacg
    13501 gcatacatgt ggcaaagatc gcaggattgc cttccaatct actagaacga gcagcagata
    13561 tcctgcatac gctagaaaat ggcgataacg gacaccatac tgttccagct gaagtagaag
    13621 agaaaactaa aacagccaaa caggagcaaa taaaaccacc tgcagaaaaa gtaaatcaag
    13681 accatataca agaccgtgta aaagaagaaa accaacagct ttctttattc agtgaattat
    13741 ccgaaaatga aacagaagtc attgaatcac tgaagcaaat aaatttacta gaaatgacgc
    13801 caatggatgc actaaacaca ttatatgaat tacaaaaaca actgtaggaa gaaggcggat
    13861 atcgatggcc aaaatccaag aattatctga acgtttagct aatcagatcg ctgcgggaga
    13921 agtagtggag cgaccagctt ccgttgtgaa agaattagtg gaaaatgcaa ttgacgccgg
    13981 cagtactcag attgatatct tagttgaaga agcgggactg cggacgatcc aagtgattga
    14041 taacggagaa ggcattttgg cagacgacgt agagaatgcc ttcaagcggc atgcgacaag
    14101 taagatccat aatcgcgacg atctttttcg catacgaacg ctgggctttc gaggggaagc
    14161 tttgccaagt attgcctctg tttctgaaat gactctggaa acggcgaatc aggaagaaaa
    14221 acaaggcacc tatctgtcgc tgaaaggcgg agaagttatt gagcatcgac cagcaccact
    14281 gcgtcaagga acgaagatta ccgtcagcaa tctgtttttc aatacgccag cccgcttgaa
    14341 atacgtgaaa acactgcaca cagaattagc gaacatcggg gacatcgtca atcgactggc
    14401 attgagtcat ccatcgattg cttttcgttt agtacatgat ggaaacaaaa tgctggcaac
    14461 tgctggaaat ggcgatctga aacaaacaat tgcgggaatc tacggattat ctaccgcaaa
    14521 aaaaatgctg aaaatcgaag gaaaagatct agattttgag ttatttggct atgtttcatt
    14581 gcctgaggtg actcgtgcca gtaggaatta cttatcgacg atcatcaatg gacgttttat
    14641 caagaacttt tccttgaata aagcaatcgt tgcaggttat gggtcaaaat taatggtcgg
    14701 tcgtttccct attgctgtat tggaaatcaa aatggacccg cttttagtag atgtaaatgt
    14761 tcatccgacg aagcaggaag tccggctgtc gaaggaaaaa gaactaacag agctaattag
    14821 taacgccatt caaaaagcat tgtctcaaga aaatctgatt ccaagtgcag cggataatct
    14881 acggtttaag aaaaaagtac ctgatcagcc taaaacagaa caaatcgaaa tcgatttgtc
    14941 ctacgctttt gaagaagaaa aacctaaaaa gccaagtagt ttgaattttg atcgagagac
    15001 aggtaccttt ttcgtagaag aactaaagaa cacatttgtt gacagaattg ttgataagtc
    15061 tgtggaaaat gttgaaaact attctggttt ttctgaagaa aacaccactt atccagaaaa
    15121 aacagcgaaa acggtggata agtttggtga aaatgttgat aactttgtag aaaaaacagt
    15181 ggaaaaatct gaaaagaaag aatttcccat tgtggataac atggagaaaa caaatgaaga
    15241 acaagcagat aaatccgtag aagaggatga aaagatttac gaggaagaat tgacactcca
    15301 tcctgaattt gatttcactc aaggaaacga caaaacatta gaacaagcca tcaagaaatt
    15361 agaaacggaa aaaccagtac aacgttttcc tcagttggaa tattttggac agatgcacgg
    15421 aacgtatctt tttgcccaaa gtagcgatgg gttgtacatc attgatcagc atgctgccca
    15481 agagcgcatt aagtatgaat atttccggga aaaaattggg gaagtatctg atgatctgca
    15541 agaattgctt gttccatttg tgttagacta tccaaacagt gatgctttga aattaaaaga
    15601 gcaaaaacac ttgctagaag atgcagggat ttatttagaa gaatttggtc aaaacagctt
    15661 tattgtacgg gcccatccta cttggtatcc caatggagaa gaagaatcga ttattcggga
    15721 gatgatcgat atgctgctga caactggaag tgtgagtgta aaaaaattcc gtgaagcaac
    15781 agcaatcatg atgagttgca aacgatcgat taaagccaac cattatttga atgaagcaca
    15841 agcacgtgtg ctgctgaagg atctggcacg atgcgaaaat cctttcaatt gtccccatgg
    15901 ccgtccagta ttgattcact ttaccaattc ggatatggaa aggatgttca aacgaatcca
    15961 agacccgcat taagtcaaag agaagaggga aaacatgaag attgtattag catcccaatc
    16021 accaagaaga aaagagttat tggctcatat cgtttcagaa ttcgagattg aacctgctga
    16081 tatcgatgaa acgccatttc cagacgaaca gcccgtcgat tatgttcgta gaatggctga
    16141 agaaaaagca cgaactgtct gggaacaaga tgaaaaagaa gaccatttag tgattgccag
    16201 tgacacgact gttgttctca atcaagagat catgggtaaa ccagaagatc tggctgaggc
    16261 tgaattcatg ctgaaaaaac taagcgggga aacacatact gtatatacag ctgttgtttt
    16321 aaaaacaaag gaacgagaag aacggatact agcagaagca catgtcactt tttatccttt
    16381 gacagacgaa gagatcaaac gctacttgga gacgggggat tatgcggata aggcaggggc
    16441 atacggcatc caaaatgctg cgagtgtatt cgtcaaagaa atttctggag attattacag
    16501 tatcgtagga tttccgattg gtgctgtcaa tcaggcactg aaaacattca tttaaacaaa
    16561 aaagcggact atctgatttt cgattgaaaa tccatgatag cccgtttttt ttattgaaaa
    16621 gattacttat ctactctgac taagatttta cttcagcttt accgactgct tcgcccgggc
    16681 gaacaagtcc tgattggtca agagaaagtc ctgcaacttt ttcattattg gtcaaagcaa
    16741 caataatgtc agttttcttg ccagcttgtt ctatttctgg caaatccatt tcagcaatca
    16801 gggtctctgg tgtgacaagg tatccttctt tcacgaatac attgaaagga acacccttta
    16861 gttcaacagt atctaatccc atgtgaacaa gtacttccag cccctcatta gaaagaatac
    16921 caatggcatg ttttgtttca aagacactcg tcactttacc gtttactggt gcatagactt
    16981 tgccgtttga cggttcgaca gcataaccgt cacccatcat tttttgtgag aaaactgggt
    17041 catttacttc agttatttcc ttgatggtcc ctgcagcgac tgcgaataat gtttcttttg
    17101 ttgcaactgc cgtaccagtt gctgaaacag gttcgaaaga ctgtggcgtt gctgttgcgc
    17161 catttgctgt ttgaagttgt acatcagcag cattttcagg aacagcagga tcaatcttat
    17221 tcaaaattcc ctgacgtcta aagatgatcg tcaagccaaa tggaatgatg acagcaatga
    17281 tcattgcgat gatgaaaggt acccatgttt ctgcttggat agctagtatt cctggcaaac
    17341 cgcctactcc gatcgcgtta gctcgaacac ccatcaagtt agcaaacatg ccagctaatc
    17401 cagagccgac cattgcagcg acgaaaggat agacgtattt caaattgatt ccgaacatag
    17461 caggttcagt tacgcctaag taacaagaaa tcattgctgg aatcgagatt tgttcttctt
    17521 ttttattccc acgatgtaag aagatgatgg ctaagactgc agagccttgg gcgatatttg
    17581 ataaagcaat catcggccat aaattcgttg atccgaaatc tgcaatcagc tgcatatcga
    17641 tggcattggt catatggtgg agaccagtaa tcactaaagg agcatacagg aatccgaata
    17701 cggcactaaa caaccagctg atagaagacg tcaatccagt atttacgata tttgagatcc
    17761 agcttccgac tgtccagccg ataggaccta aaataacgtg tgcagctaaa acagttggta
    17821 acaatgaaaa caatggaaca aaaatcatcg agatcgactg agggatatat ttgcggaaga
    17881 agatttctag atacgctaac ataaaccctg ccagcatggc tggaataact tgcgcttgat
    17941 aaccaatcat ctggacttga gcaaaaccaa aatcccaaaa tggaatatct gctgcggctg
    18001 tggaagctac actataagca tttaataatt gcggagaaac taacgtaatt cctaaaacga
    18061 ttcctaatat ttgtgtagta cccatctttt ttgcaatact ccaagtgata cctactggaa
    18121 gaaaatggaa aattgcttca cccggtaacc acaaaaaggc attgacacca ttccaaaact
    18181 tcgagtgttc aacgattgtt ccaccaagac tttcaaactg gataccttca agtacatttc
    18241 tgaatccaag gatcaatcca ccgacaatga ttgcaggaat cagtggtgta aagatttctg
    18301 ctaaaacggc aatagcacgt tgaacgggat gaaggttttg ttttgcagct gcttttcctt
    18361 gttctttgga aaccccttca actccagata ctgcaacgaa gtcgttataa aaagtagaaa
    18421 catcgtttcc tatgatgact tggaactgtc ctgcattcgt gaacatccct tttacgctag
    18481 gtatatcttc gatcgctttt tcgtccgctt ttcctggatc attcaggaca aaacgcatac
    18541 gagtcgcaca atgactaact gcagcaatat tttcttttcc gccgatatca tgtaacagct
    18601 tctcggcatc tgcttgatat tttgccatat caataaaccc ctttctctta acttgtctat
    18661 gcaagttgtt tcttcattta ctatactttt tttcggagag aattgcaagc gttttattaa
    18721 aaagtacgag agaaaatgat atcgttttaa aaagcttaaa ataagctttt cttaaaaata
    18781 ggaacattga aatacaaaaa gagctgtagt atagtgaaga aatgatggaa gaacgagtga
    18841 gggaaaaaac atgaataagt tcaatgaaat ttttttagat ttggaacaga aaattttagc
    18901 gaaagaatat cctccgcatt cgcttttacc cagtgagaac caattgatca aaatttatgg
    18961 tgtttcacga gaaacaatta gaaaagcgct gaatcttttg actacggaag gttatattca
    19021 aaaaaaacaa ggaaaaggtt cgatcgtact ggatcggaat cgcttcgact ttcctatttc
    19081 tggattgact agctataaag agctacagga gacccaacgt attccaagtg aaacgatcat
    19141 ccatacgtta gaagaaacag aagtgacaaa agcattgaac gagatcactg gctgggagat
    19201 cggtgcgcct gtttggcatt tgatacgcga aagaaaaatc aatggcgaag tagttatatt
    19261 agacaccgat tatctattaa aggaaatcgt tcctatttta actccagcac aagcacaagg
    19321 atcgatctat gaatattttg aaaatgagct ttctttgacg attgcttacg cgcaaaagga
    19381 gatcacagta gaagaagtaa cggaaatcat gaaaacagcg atggatcttc acgatgacac
    19441 ttatgcagta gtagtcagaa gcctcgttca tctggaagat acccgctgtt tcgagtattc
    19501 tgagtcggtt caccgattag ataaattccg tttcgttgag tttgcccgac gccgaaaagt
    19561 gtaaatagtt caaaagaaag caaattgttg gcatctgtcc actttggcgc tatgatagga
    19621 tcacaaaggg ggcattttta atggataaac caataagacc agaaaaagaa gaactgaaag
    19681 aaaagttatc acccatggct tatgcagtca cacaagaaaa tgcaacagaa cgaccattta
    19741 gcgggaaata tgatgatttt tacgaaaagg ggatctatgt agatatcgtc agcggtgaac
    19801 cgttattcag ctctgcagaa aaatatgatg caggttgtgg ctggccatca ttcagcaaac
    19861 caataacgaa aagacaagtg cgcgaaaaag ccgatttttc tcatggcatg catcgaatag
    19921 aagttcgaag caaagaagca gattctcatc tcggacatgt gtttaccgat ggaccagtag
    19981 atcaaggtgg tctacgttac tgcatcaatt ctgcctcact gaaattcatt ccatatgaaa
    20041 agatggatga attaggttat ggggaattca aatcacttgt agaataatgg aaatacacaa
    20101 agagcggtac aatacgggga tttactcgat cgtccgctct ttttttattc aagcgattgc
    20161 tatttgaaag aaacgctccc tagactcctt ttttcacaag gtgaaatgtg ctacaataaa
    20221 gggaacgtat gtgtgcaaaa gaaagaggac tagaatatgt atgaatatct gacaggtgtg
    20281 gttaccttta tcaaccccta ttacatagta gtagaaacca atggtatcgg ctaccagatc
    20341 gcactaggaa atccttaccg ctacagtagc aaactaaatc aaaaaataaa aatttatgtc
    20401 catcaggtaa tacgtgaaga tgcgcatctt ctgtatggat ttgattcgct agaagaaaag
    20461 caactgtttt tgcgattagt aagtgtttca ggaatcggtc cgaaaagtgc ccttgcaatc
    20521 atggcaagcg aagaccactc cggtttgatt caagcagtag aatccagtga tgtcacttat
    20581 ttgacgaaat ttccaggagt agggaaaaag acagcacaac aaatgatctt ggatctaaaa
    20641 ggaaaattcg gtgagctgag tatcgataca ccttttagtc tatttgatga agcaaacaca
    20701 aaagacgcta cagctctatc tgaagcaatg gaagctctct cggctcttgg ttacagtgat
    20761 cgagaaatca aacgtgtaga aaaacaatta aaagaagtag ataatcagac aacggatgag
    20821 tatctacgcc aagcactcaa gctaatgatg aaaaaataag gaggagacca aatgacagat
    20881 gaatacttgt tatcaccaga atctggcgaa aatgaactga gtttggaaaa atctcttcga
    20941 ccacagctgc tttctcaata tatcggacag agaaaagtca aacaagaact tcagatttac
    21001 atcgaagctg ccagaaatcg ggaagaacct ttagatcatg ttctgttgta cgggcctcct
    21061 ggattaggaa aaacgacgat ggccatggtc attgctaatg agatgaccgt aaatattcgt
    21121 acgacgagtg gccctgctat cgaacgtccg ggtgacttag tagcaatctt gaatgaactg
    21181 gaagcagggg atgtcctgtt tatcgatgag atccatcgat tacctagagt ggtagaagag
    21241 atgctttatt cagctatgga agatttctat gtagatatca tggtaggaca agggccaacc
    21301 gcacatccgg ttcatttccc tcttcctccc tttactttga ttggcgcgac gacacgggca
    21361 ggtatgcttt ctgcaccttt acgagatcga tttggcatca tttctcatat ggaatattat
    21421 gacgaacagg atctgcagga gatcgtttta cgttcttcgg atatttttca aacagagatc
    21481 attgaagaag gggcattgga aattgctcgc cgatcacgag gaacgcctag aatcgctaat
    21541 cgcttgctca aacgggttcg tgattttgcg caagtccaag gagacgggaa aatcgatcgt
    21601 cctatagcgg atcaggcact tactttgcta caggtcgatc aggctggatt ggattatgtt
    21661 gaccagaaat tgttgcgaac aatgatcgag ttatatggcg gcggaccagt agggttaagt
    21721 acgctttcag taaacatagg agaagagcgt gagacggtag aagatatgta tgaaccgtat
    21781 ctgatccaaa aaggattttt aaagcgtaca cctagagggc gaattgctac tgcttatgcc
    21841 tatgaacatt ttggttacga ctatcatata tgatttttgc ttttagattg gaggaaaatg
    21901 aatgagtgat acaacacgta cgaaacaatt gatcaaaaac gtattgattg atttgtgcca
    21961 aacgcaatct tttcgaaaaa tcagcgtcca aaaaatcgca aacgaagcaa aaatcaatcg
    22021 acaaacattt tattatcatt ttacagataa atacgatttg cttcgttggg tctattgtga
    22081 ggatgcattg cattatttag atccacaatg tctttcactt gataattggg aagagcaagc
    22141 attgaaaatg ctgaaagcaa ttgctgagaa gaaagaattt tatgcaaata ctgtgctttc
    22201 tgacccagaa attttacaaa aagagttttc tcaactgatc caaaaatcat ttatcaagat
    22261 ttttgaacaa atggatgaag aaagacaact ttctgcaaga gacaaactat tttatgctcg
    22321 ttttttttct tacggttgca gtggtgtatt agtcaattgg atcacgaatg aatatgaaga
    22381 aacaccgatg gaaatcgcta tgcagctttt ccgtttagcc aaggatacgg aattatattc
    22441 ttatcgtctt tatgcaaaag aagagttgga agaacagtaa tagaaaaatt ttttgttgga
    22501 aaagcaataa tcgctaaaag gagatgggga aatgacaaaa attttatttg tttgtttggg
    22561 aaatatttgc cgttcaccga tggcagaagg cttgctgaga aaacgaatag cattagaagg
    22621 aagggaagca gaattttttg tggattctgc tgctacaagc acgtatgaag ttggaaagac
    22681 accgcaccct ggaacgaaaa aaatattaaa ccaagaaaaa gtagatatga cgaatatggt
    22741 tgctcggcaa atcacacccc acgattttga aacttttgat tggatcattg gcatggatca
    22801 agaaaatgta gaagaactga aacgaagagc accacgctca gcgcagggga aaatccattt
    22861 gtttttaagt agcattcctg gaaaagaaaa agaaaatgtt cccgacccat actataccaa
    22921 taactttgat gagacatatc acttgatcac agaaggcctg aatcattggt ggaatatttg
    22981 gattgatgaa aataaaataa caaataattt gtaaagttaa cgctttcttt ttaaggcgat
    23041 gttagagcat ttccttgttt ttttgtaaaa tgttaggtaa aataaaatta attaagtaac
    23101 actttcttag ctaaaggagg agtgcattcg atgaacgaag agacagtatc gccaatgaag
    23161 aagcttacga agttagttac tcatacttcg tatcaacttt ttgattcttt tgtaaatgac
    23221 actgaagaac atgctaagaa tgtacgattg caaggaaagt ttattcttga gctgcaaaaa
    23281 gctgctactg aacatagtct agttatctta caagtaagag caaatcgttt gagtagcaag
    23341 tatgaaacga tctcaggctg ggtggcgaca aaaacggtcg aaaaagaccg agtgatgatc
    23401 cgcctacaaa acgaagagca gcagatccgg atggttcctg tagaacaaat tgaaaaaata
    23461 acaatccttt caccagcagg ggaacaggaa cggttatcaa aataatttat accagataga
    23521 aaagcacgta tgagcttgta ccatcaatca ttactaatca aaaataaccg aatgctttaa
    23581 gctgatatca gtaaaacgga acgttttagg atgagtatca tagcatgaca gcattcggtt
    23641 gattagttga atcgattgga tggtacaagt ttttttgata aaaaaaggtc ctgctagccg
    23701 gggagctagc aggataagga gttaaaaatg aaaaagtgtt gttagggttg tttgttggta
    23761 tgcttatata atagtcatta gttgtgaata ttttgtgacg aaagttttcg aaagttgtta
    23821 agtt
//
LOCUS       DAIGTA010000045        23457 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.046, whole genome shotgun sequence.
ACCESSION   DAIGTA010000045 DAIGTA010000000
VERSION     DAIGTA010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.046"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            288..695
                     /locus_tag="NOB43_001890"
     CDS             288..695
                     /locus_tag="NOB43_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982744.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="NOB43_001891"
     CDS             709..1110
                     /locus_tag="NOB43_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982745.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="NOB43_001892"
     CDS             1112..1483
                     /locus_tag="NOB43_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982746.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1856..2056)
                     /locus_tag="NOB43_001893"
     CDS             complement(1856..2056)
                     /locus_tag="NOB43_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0982747.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(2361..3593)
                     /locus_tag="NOB43_001894"
     CDS             complement(2361..3593)
                     /locus_tag="NOB43_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCI0982748.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            3847..4416
                     /locus_tag="NOB43_001895"
     CDS             3847..4416
                     /locus_tag="NOB43_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0982749.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4594..5034)
                     /locus_tag="NOB43_001896"
     CDS             complement(4594..5034)
                     /locus_tag="NOB43_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCI0982750.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5192..5956
                     /gene="map"
                     /locus_tag="NOB43_001897"
     CDS             5192..5956
                     /gene="map"
                     /locus_tag="NOB43_001897"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCI0982751.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            5988..6911
                     /locus_tag="NOB43_001898"
     CDS             5988..6911
                     /locus_tag="NOB43_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HCI0982752.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            6987..8126
                     /locus_tag="NOB43_001899"
     CDS             6987..8126
                     /locus_tag="NOB43_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HCI0982753.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8119..8919
                     /locus_tag="NOB43_001900"
     CDS             8119..8919
                     /locus_tag="NOB43_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0982754.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            8919..9746
                     /locus_tag="NOB43_001901"
     CDS             8919..9746
                     /locus_tag="NOB43_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0982755.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9724..10458
                     /locus_tag="NOB43_001902"
     CDS             9724..10458
                     /locus_tag="NOB43_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0982756.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            10558..11424
                     /gene="rfbA"
                     /locus_tag="NOB43_001903"
     CDS             10558..11424
                     /gene="rfbA"
                     /locus_tag="NOB43_001903"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCI0982757.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11438..12010
                     /gene="rfbC"
                     /locus_tag="NOB43_001904"
     CDS             11438..12010
                     /gene="rfbC"
                     /locus_tag="NOB43_001904"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCI0982758.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12032..13060
                     /gene="rfbB"
                     /locus_tag="NOB43_001905"
     CDS             12032..13060
                     /gene="rfbB"
                     /locus_tag="NOB43_001905"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCI0982759.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13158..14009
                     /gene="rfbD"
                     /locus_tag="NOB43_001906"
     CDS             13158..14009
                     /gene="rfbD"
                     /locus_tag="NOB43_001906"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCI0982760.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14044..16077
                     /locus_tag="NOB43_001907"
     CDS             14044..16077
                     /locus_tag="NOB43_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982761.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16121..17401
                     /locus_tag="NOB43_001908"
     CDS             16121..17401
                     /locus_tag="NOB43_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HCI0982762.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17611..18417
                     /locus_tag="NOB43_001909"
     CDS             17611..18417
                     /locus_tag="NOB43_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982763.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18429..19649
                     /locus_tag="NOB43_001910"
     CDS             18429..19649
                     /locus_tag="NOB43_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982764.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19639..21225
                     /locus_tag="NOB43_001911"
     CDS             19639..21225
                     /locus_tag="NOB43_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0982765.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21264..23402
                     /locus_tag="NOB43_001912"
     CDS             21264..23402
                     /locus_tag="NOB43_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0982766.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALKMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7491 a         3909 c         4818 g         7239 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttata cctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgcttcgtgc gtctggcacg tcagtcacga tatcaaacaa
     1621 aaagtataca tccttcttca ttctagtttt cgcagcagga attttaatat actgaataat
     1681 agaaaacaag tacttgtgcc aaattatgtg ccaaaaaaat tcgaattcaa caaaatgtaa
     1741 acaaatagaa aaccttctat attaagattt cctgcaataa caaacacaac agaagacgtg
     1801 taatagttag tcaggaacgt acaaataacc cctgtatcct ttgcggtaca gggggttatt
     1861 ttgtataagt agacattgta gtttctaaac tgctatgtcc taaacgtttc gatacgctaa
     1921 gtatatttac tccttgataa agtaaaatag atgcatgcgt atgtcttagt ccatcaataa
     1981 acagtcgaag agaaaatagg gaaaaattga ttactaaaga aaaacttact aggtcgacgg
     2041 tgtagttgat tttcatactt caatagattc gaattaaacg atttcgattg gcttatacca
     2101 gtcctatcca acgaaagata tatcgttctt aactctagcg gtataacttg aagctttacg
     2161 taaagccaat gggaatgaac tggagatgac tttttattat ttttagtaat agctgatggg
     2221 ttaatactta caactttcct tttcaaagta ccatataaaa aaacggtggg gttgtttagc
     2281 gaaataaagg atctaagcca atagcttaga tcctttattc tatgctttat attatttttt
     2341 gcatgtgtgc gaaagtatac tcaagcccaa tcgccatttc ggaaaatcgg tactgtagag
     2401 ccatcttcac ggattccgtc gatatccatc ttgtcagatc ctaccatgaa atctacgtgg
     2461 gtttgacttc tattcaatcc agcttctgct aattcttcat cggacatttc tgtaccgcct
     2521 ttcacactga aggcataagc agaacctagt gctaagtgat tcgatgcgtt ttcatcaaat
     2581 aatgtattga aaaagatgat gccagattga gaaataggtg aagggtcagg tacaagtgcg
     2641 acttctccta aacgacgcgc accttcatct gtatcaagca gttttgctaa gacatcttct
     2701 ccttgttcgg cagaaaaatc aacaactttt ccatctttaa aagtaaattt catacccgag
     2761 atgatggtgc cagcataact cagtggcttt gtacttgaaa tgtaaccatc tactcgatga
     2821 ctgtcaggtg ctgtgaacac ttcttccgtc ggcatatttg ccatgaattt ttctccacga
     2881 gcattatagc ttccagcgcc ttcccaaaga tggtttttag gcaatccgat aatgatatct
     2941 gtaccgggag cagtatagtg aagggcagaa aattgttctc gattcaattc ttctgctttt
     3001 tttgctaatt tttcatcatg cttcttccat gctaagacag ggtcttcttc atagacacga
     3061 gtcgttttga aaatctgatc ccataatgcc tcaacttgtt tttcttctgg cagttctggg
     3121 aagacttttg ctgcccattg tttaccagcc gcagccacga cagtccaact gactttattt
     3181 gcttgagttg ccttgcgtaa attcattagt gctttgccat tcgctgattg ataagacgct
     3241 actcgatggc tatctacacc agcaaatgca tcgggatcgg cagaaacaac gctgatcctg
     3301 cttgctcctt tttcaagcca ttcatccgct tgatcgattt tagattgtgg tacattctca
     3361 atacgatccg ttgcagcatg taaaagaaat tctctttgga tctggtcgtc agtccattga
     3421 acgataacct cagcggctcc tagtttataa gcttcttgtg tgatcaatcg agcaaggggt
     3481 gcctgttcca cgctgatctg taaaacaact gtgtgtcctt tttctgtggc tacgccagtt
     3541 tctgcaatta agcgtgcata tttttttaga agttcattaa aatcagataa cataataaaa
     3601 attcctcctc accatttttt ctggtaacta ttagcatgat accatttaat tatgattcaa
     3661 acaatgaggc tttaaataaa aaaaggaggt tattttttta aggttaagtt tcatgatata
     3721 tgttactact tgctatttca gcttgtgaag aaaatcaaaa actaattttg catatcaaaa
     3781 aaacatgtta caatgaaatt aatcaatggt ggaagcgtta taaaaaaatt aaggagatta
     3841 aaaaatatgg caagaaaaaa gacgattact agagaacaga ttttggcagc tgcttatgaa
     3901 gtagctgcca ccgatggatt tacacgattt actgcgagaa acatcgcgaa caaaatgaat
     3961 tgttccacgc aaccgattta tcttgagttt aaaaatatgg atgacttgag acaagctctt
     4021 tttgagcaga tctatgatca tttacaatat gaagtgttca ctgttgagca tacagggaat
     4081 acgattatcg atcttgcttt taattatatc cattttgcaa gaagagagaa gaagttgtat
     4141 cgttcactgt acttagaaga atatggtgga ggaaaagaga tgcagaattt ctcttatact
     4201 tactttgtga atacagtgaa acgcgatcca gcttatgtga atctttcaga agagcagatc
     4261 gaatctttgt ataatgggac atggatcata gctactggga tcgcagcttt gatgtcttca
     4321 agcatcatcc atccaactga tgaacagatt gaaaagatga tccaagacag tatagatgct
     4381 atcttgaaat tcaaagaacc aatcgaaatc gattgaatat actcaaaagt tccacaaatc
     4441 agtaggtaac aagagatgtg tcaaaataag gaaaagttcg tttttcttac agcgtatgca
     4501 tttttaactc ccgaagaact cttccatgaa tgcaatgaat aaaagagcca tacagattga
     4561 ataaatctgg atggctcttt tattgcaagt atattaaatt tttgcgacta gttctttagc
     4621 gaaagcttct aaattttcga tatcttcttc ttcagcattc agatccactt taacattttc
     4681 ggctcctttt gatgcgcctg tttttgcaaa agcagcatcg aaatcatcca ccgatttgca
     4741 gaattcatcg taaaaagtat caccagatcc gcagacaccg taaatttttc ccaatagatc
     4801 caattcttgc aagtcttcat aaaagtctac gatctcatca ggcagatcgc catcatcgta
     4861 tgtataagta gctactacgc aaatatctgc ctcctcgaat tcatctgcat ctacttgggt
     4921 acattcgttg atttcgactt cgatatccag attttcaaat gcttctgcaa caatatcggc
     4981 gatttcttca gtgtttcctg tcatgctagc atatacgatt tttgctaaag ccatgatgtg
     5041 cctcctcgtt tataattatt taacaattat gaattatacc aaaacatcat tgaaaagaaa
     5101 ataaaaccta aagacacctg gggaatgtca tttggctaaa tgtatgccgc tatgttaaaa
     5161 tgagagggat ttgtaaaaag gagacgaaaa tatgattact ttaaaatcag cacgtgaaat
     5221 tgaaatgatg gcagaatctg gagctttatt agcagatgta cataaaaatc tgcgtgattt
     5281 tataaaacca ggaatcacaa gttgggatat tgaggtattt gtcagaaact atatcgagag
     5341 tcatggcgga attgctgcgc aaattggctt tgaagggtat gaatatgcga cttgtatcag
     5401 tataaatgat gaaatttgtc atggattccc tcgtaaaaag cctttgaaaa acggtgattt
     5461 ggtaaaagtc gatatgtgta tcgatttgaa aggcggcatt tctgattctt gttgggccta
     5521 tgtagttgga gaatctacac ctgagatcga ccgattgatg gaagtaacga agaaagcttt
     5581 gtacatcggt attgagcaag cacaagtagg gaatcggatt ggtgacatcg gtcatgctat
     5641 ccaaacttat gtagaaggcg aaaatctagc gatcgttcgt gattttattg gtcatggcgt
     5701 tggtcctacg attcatgaag aaccagcagt tcctcattac ggagaagctg gaaaagggtt
     5761 gcggttgaaa gaaggcatgg ttatcacgat cgaacctatg gttaataccg gaacttggaa
     5821 aatgaaaatg gatcctaacg gctggactgc gtatacaaga gacggcggac tttcttgcca
     5881 atatgaacat acattggcta ttactaaaga tggtccaaga attttgacat cacaaggaga
     5941 agaaggcact tattgatcta tccagtcaat aggtacggga gaggtacatg aaagtttgga
     6001 acaaaataaa acaaaatgaa aatctgatgc gctttattga gacgactcaa aagcgcatca
     6061 ctgattcaga aatgagtacg acctctgtcg tcgttgctta ttatttactc ttgtctttat
     6121 ttccattgat tattgctttt ggtaatattt taccgtttct ccacatcgat caagagactg
     6181 tactgaccta tttacgagaa gtgattcctg agaccgttta ccagtttatc ggtcctgcaa
     6241 tcaaagacct tttgacacaa agttcaggag gcttgttatc cgtttctgca ttagcggctt
     6301 tatggtctgc aagtcaaagt atcaatgctt tgcaaattgc gatgaataaa gcgtatggcg
     6361 tagaaaatag aaaaaatttt ttgatcgtcc gtttcttctc actaattgtc attgtcttgt
     6421 tcatgattgc tattagtggg gtaactatcg ttcttgggtt gggacagctg attttggatg
     6481 ctattcagcc aatcgtacaa atacccgtga actttatcga tcagttccaa actttgaagt
     6541 ggccaatcac attggtagct ttatttgtca tcatgttctt gatttattta attgtcccta
     6601 atgctcagtt gaagttgaag acgatcattc cgggcacgat cttcgctact gtcggctgga
     6661 tgctgttatc acaagtgttt agtatctatg ctaggtattt tgcaacgagg atcagcggtt
     6721 atcagatcat aggaagtttt attgtactca tgctttggct taattttgct gctacgatca
     6781 tcattttggg cggaatcatc aatgcagttg ttcaagaata cgtgacgggt catcaaatca
     6841 aaaaacgtcg agatccaagc cgaaaatggt tcaataaatt gaaaactaaa ttttctcata
     6901 aaaaaaagta gaaacaagag ttcttattgt aaatttatat cagtaattta taataattat
     6961 gactcttaat taaagtaggt gcccatatgc ttgtttcttt tagtatggtt ataagatttt
     7021 ttctgacaat tttattatca ctgatattaa cacctgtatt caaaatcatt tcagtacaaa
     7081 caggtatggt cgacaaacca aatgaaagaa gaataaataa agttccaatg ccttcagcgg
     7141 gcggactgcc tatctttatt tcatttgtta tatcgacttt attcttattc cgtaaaatta
     7201 tccctcaatc gtatattgta ccgatcttga ttgcttcttt agtaatcata gtcacaggag
     7261 tgctcgatga taaatatgag ctgacaccta aacaaaaaag tatagggatc ttgattgctt
     7321 ctcttattat ttattttgta gcagatatac gtattgattc cttcacgctt ccttttattg
     7381 gatatatcca actaggctgg cttagttttc ccgtaacgat tttttggatc ttcggtatca
     7441 cgaatgcggt caatctgatt gacggtttgg atgggctggc ggcagggatt tcattgatcg
     7501 gtttaattac gataggaatc attggatatt ttttcctcca tgcttctaca gtgtatattc
     7561 cagttgttat tttctgtctt gtagcaagta ttatcggttt ttttccttac aatttttatc
     7621 cggcaaagat ttatttaggc gatacaggag ctctattcct agggtttatg atggccgtcc
     7681 tttcactaca agggctgaag aacgtgactt ttgtttcatc gatttctttg ctgatcgtca
     7741 tgggagtgcc ggtaacagac acgttttttg ctatcattag gagaaaagca aaccgtgttt
     7801 ctttttctac agcagataaa aaacatcttc atcaccgact aatcagttta ggctttactc
     7861 ataaaggtgc tgtcctgacg atttatgcga tggctttgat gttttctttc acagctatgg
     7921 tcatgaatta tactggaaga atcggaacga tcatattgat tattgccatg ttgtttgctg
     7981 caattttatt atttgaattg attggtctga tcaatgagaa acatcagttt attttaaaaa
     8041 cattgcgatt tttagggaat aaagagtacc gtacgcaagt aaaacagaaa tatttgaaga
     8101 aatggaaccg tcatatagat gaataacaaa ttaaaccagc cgatccttat tagtattgtg
     8161 acggcaaaca gtgataaaat ttttcggaca ctagataatt ttatttcaac tgtaaaagat
     8221 gaaacagcag taaaaatccg aatttttgac aacaattcac ttcccgagta caaaaaaaga
     8281 ctaacagagt ataggaaata tccctacatc gatatctatt ttcatgatga aaattccgga
     8341 tttggttatg gacataatca caatctgata gctagcgatt ctcgctatgg cattatttgt
     8401 aacccagata ttttagtgga tgaagagaca gttacagcat tggtcttgtt attgaaagaa
     8461 catccggaat gtgcgatgtt agcacctaag attcttaatg aagatggaac aactcagcac
     8521 ctcatccgtg agcagctggc tgtttttgat tacgttttgc gctttgtgcc tttcaaatgg
     8581 gtcaaaaaaa agtttgacaa acgactggct gtgtttgaat gccgaggatt gcctactgat
     8641 gctaatagtt atgtacggat gatctcaggt agttttatgg tagctgatat tgataaattt
     8701 aaagagataa aggggtttga tgagcgtttc ttcatgtact ttgaagacaa cgacttgtgt
     8761 ttgagttttg aaaaagcagg ttacaagtta ttgtacacac ccttttatgc agttatccat
     8821 ttttacggga agggtgcgca tcgaaatgca aaactgtttc gcgtgttttt gacttctatg
     8881 atgaaatttt tcaataagtg ggggtggcgt tttttctgat gaaaccagaa atattagtag
     8941 tcgttgtgct ttatcagcaa ctattcagtc aatctccagc ttatggacca ttaagcaaag
     9001 cacttagcga aaagcaaatt cagcttatta tttacgataa tagtcctcaa aggcagcaaa
     9061 atgagctgtt tgaaaaagaa aatatcgttt atcatcatga tccgcaaaat cctggtttag
     9121 cggtggctta taattttgcg ttgtctcaag cagatgaagg aacacgttgt ctcgtcactc
     9181 tggatcagga tacgaggcta gtcgacgatt attttgaact attgcgtaaa gtaaccttta
     9241 cagatgaatg tgttgctgca gttccgatga ttttttctgg gagccgacaa gtttctcccc
     9301 tatattcaga tcgttatatc aatcgtacag ctcaagcagt agaagttgaa ggcccaacag
     9361 ctgaacgaat catggcaatc aattcaggtg ttgcctggtc tgtcaaattt ctaaaaaaga
     9421 ttggcgggtt taatcctgct ttttctttag attttttgga tcattggctg ttttggaaag
     9481 tggatcagtt ggaaaaaact gtggagatcc ttcctgtacg aatggaacat gatctttcgg
     9541 ttttagacta tgaaaaagtt tcaagtaatc gataccgttc tattttacaa gcagaaaatc
     9601 gattttatca tgaatatgat caaaggcatt tatccagtca ccgacgacaa ttattgttaa
     9661 gaacagctaa acagttcttg accgtcaaaa accggcatat ctggcggatg actttgcgct
     9721 catatgttaa gaattggaag gtgtgaattc gtgcgttcgg tttgtatagc tacctttaat
     9781 ggaggcagat atttaagaga gcagttagat agtattttat ctcagctttc agcagaagat
     9841 gaagtagtca tttctgatga tgggtcagta gatgatacat gggatatatt aactgaatac
     9901 gcagaaaaag ataagcgaat ccagcttttt tcggggcctc gtcaaggatt gatcgctaat
     9961 tttggttatg cgatccagca gacgaaagga gatctaatct ttttggcaga ccaagatgat
    10021 gtttggttgg agacaaaagt gaaaaagatc actgactatt ttgagcagaa tccggatcag
    10081 ctagtagtag tttctgattt aatcattgtg gacagcgagc tgcaagagat ccatgattcg
    10141 tatttttcgt ttcgaaattc caaagaagga tggcttaata atgtgataag aagtcactat
    10201 attggtgctg gtatggcttt ccggtcttct ttaaaacccg atattttgcc gatcccgtca
    10261 gaagtgccga tgcatgatat gtggattggt ttgctgggag gaaagaagac tgggttccta
    10321 agagaaccgt taactctgta ccgaagacat gatttaaacg cgagtgagat tgaaacacat
    10381 tctaaattac ggcaaaaaat ttcttggcgt gttcatctga ttacggcgtt gatcaaacga
    10441 aaatggttta aacgttgata aaagatgttt aaatccttaa tatttccatg acaaatataa
    10501 caattgatga gataataaca aagtgaaatt tgaaatcaaa aaggagagca gatatccatg
    10561 aagggaatca ttcttgctgg gggcagcgga acacgtctgt accctttaac aaaggcaaca
    10621 tcgaaacaat tgatgccgat ttatgacaaa ccaatgattt attatccaat gtctactctg
    10681 atgttggcgg gaatcaaaga aattctgatt atttcaacgc cacaagatac accacgtttc
    10741 aaggaattat ttggaaacgg aaatgattta ggactgcaga tcgaatatgc agtacaagaa
    10801 agtccagatg gattggcaca agcgtttatc attggagaag aatttattgg agatgatagt
    10861 gtctgcttgg tattagggga caatatttac tatggtggcg gtctgtctaa aatgttgcaa
    10921 cgagcagctt caaaagatac aggcgcgaca gtatttggct atcatgtcaa tgatccagaa
    10981 cgctttggtg tagtagaatt tgatgagaat atgcaagctt tgtcgattga agaaaagcct
    11041 gctcagccaa aatcaaatta cgctgtaact ggcctttatt tttatgacaa tgaggtaatt
    11101 tctatcgcta aaggtatcaa accttcagaa cgtggagaac tagagattac ggatgtcaat
    11161 aaagcatatt tggataaagg aaaactatcc gtagaactta tgggacgcgg atttgcttgg
    11221 cttgatacag gaacacatga atcattgctt gaagcatcta cctttatcga aacaattgaa
    11281 aaacgtcaga acttaaaagt ggcttgtttg gaagaaattg cttaccgtat gggctacatc
    11341 gataaggaac aattgctggc ccttgcacag ccattgaaaa aaaatcaata cggtcaatat
    11401 ttattgaatt tggccgctga ataaggagtc cttacagatg aaagtaacag atacaaaatt
    11461 aacagatgtc aaaatcgtag aaatggacgt ctttggcgat catcgcggtt tcttcacaga
    11521 aagttattca aaagcaaaat ttgcagaaca tggattgaaa tatgactttg ttcaagacaa
    11581 ccattcacta tcagctgaag ctggtgtcct tcgggggctt catttccaaa aaggagaagc
    11641 tgcacagaca aaattgattc gggtagtcac tggagcagtt ttagatgtag tagtggatat
    11701 ccgcaaaggt agcccgactt atggtcaatg ggacggattt atcttatctg aacataatca
    11761 tcgacagttg cttgtaccta aaggatatgc ccatggattc gttactttga caccaaatgt
    11821 gaacttcctt tataagtgtg ataattacta taatgcagaa gcagatgggg gcatcgcatt
    11881 tgatgatcca gatttagcga ttgattggcc aattgatcca tcaagagcga ttatgtcgga
    11941 aaaagatcac cgtcatccga cattaaaaga atttgaagca gaaaatccat ttgtttacgg
    12001 agaaatctaa gaattaagga gaaattttct tatgaaaaac atcattgtta ccggaggtgc
    12061 cggattcatc ggctctaatt tcgttcatta cgtggtaaac aatcatccag aagtgcatgt
    12121 cactgttttg gataaactga cttatgcagg aaacaaagag aacttggccg gacttcctag
    12181 cgatcgcgta gaattggtcg taggagatgt tgcagatgca gaattagtgg accgtctagt
    12241 aaaagaagcg gacgcagttg ttcattacgc ggcagaatcc cataacgata attcattaaa
    12301 agatcctttc ccatttgtac aaacgaatat cattggtacg tatacacttt tagaagcttg
    12361 ccgcaagtat gatgtacgct atcatcacgt atctactgac gaggtttacg gcgatcttcc
    12421 attacgtgaa gacctgccag gacatgggga aggcgaagga gaaaaattca ctgcggaaac
    12481 accatataat ccttcaagtc catattcttc tacaaaagct ggttcagatc tgttagtaaa
    12541 agcatgggtg cgttcttttg gcttacgtgc aaccatttca aactgttcaa acaactatgg
    12601 tccttatcag catattgaaa aatttattcc tcgccaagta acgagtatct taagcggtat
    12661 tcgtccaaaa ttatatggcg aaggaaagaa tgttcgtgac tggatccata cgaatgatca
    12721 ttcttcagca gtgtggctga ttttgacgaa aggcagaatt ggcgaaacct atctgatcgg
    12781 tgcagacggt gaagaagata ataagaccgt gatggaattg atcttagaaa tgatgggcca
    12841 accaaaagac gcatacgacc atgtaaacga ccgcgcaggg cacgatttgc gttatgcaat
    12901 cgattcgaca aaattgcgag aagagctagg ttggcagcct gagtttacga acttccgtga
    12961 tgggttggct gacacgatca aatggtacga agaacatgaa gactggtgga aaaaagaaaa
    13021 agaggccgtt gaagcagcat atgccaaaaa tggacaataa tacagaggaa atttcactgt
    13081 attaatggaa aaacacatgt gaggcaggcg ctcgcctgtc tcttttttaa aataaaaatc
    13141 aaggagcgga taaccatatg tttttattaa ctggaggaaa tggacaatta ggtacagaat
    13201 tgcgccattt attagatgaa aaaaatctgc catatgtttc aacagatgca aaagacttgg
    13261 atatcacaga tgctgagaaa acaatggctt atattacaga attaaaaccc gatgttattt
    13321 tccattgcgc agcttacaca gcagtagata aagcagaaga agaagcaaaa gaattagatg
    13381 agaaaatcaa tgtcgatggc acaagaaatg tagcacttgc agcaaaagct gtgaatgcac
    13441 aattcgtcta tatcagtaca gactatgttt tcgatggaaa aaacaaaaat gtagaatacg
    13501 aagtagacga ccaaacgaat ccactaaatg aatatggtcg tacgaaatta ttaggcgaaa
    13561 aagcagtaga agagatttta gaagactatt atatcatacg aacttcttgg gttttcggga
    13621 tctatggaca caatttcgtc ttcacgatgc aacgcctagc ggaaacccgc gacaaactga
    13681 ctgtagtaaa tgaccagttt gggcgaccaa cttggacacg tactttggca gaatttatgg
    13741 tatatgtcat cgaagaaaaa gcaccatttg gtatttatca tttgtcgaac gaaaatagct
    13801 gttcttggta tgagttcgca aaagaaatat tgaaagatac agatgtagaa gttgcacctg
    13861 ttacgtcaga agaatttccg caaaaagcaa cacgtccgca gtattcagtc atgagcctga
    13921 aaaagacaga agcgttaggt tttgtcatac caacttggca agaagcactt gcgcaaatgc
    13981 tggaagctgc caaaaaaatg aataagtaat ttccttttta tcaaatagaa tttggagcat
    14041 gatatggaaa aacaaacaag aagtgcacga cgaaaagaaa agccaaaagc gaatcaggca
    14101 gattcgaatt tggtgcttga cctgtttcta aaactccgct atcttattgg cgttttagtc
    14161 atcgtggtca tcgttacttt taatttaaac ggaagttcac ttggtgtttg ggataaatat
    14221 gtgtcgcaaa gagacgatgg gaaaaaaact gatgtgattt ttggacagaa tcgggaagtg
    14281 cggtcagacg aatggctggt gcagacacct ttttacctct cacaagctga agaggacttt
    14341 tcgttggtga acgaggatta ttcattaaac ggacaaaaca tgatcattgc gtataattct
    14401 cctgtaaagg atattacggt tatcggaaaa ccattcaact ggggattctt tttcctcgga
    14461 agagatcgag gactttcctt ttattgggcg atgaaattag tcgtcatggt cttgcttgga
    14521 ttcgaagtac tgatgatatt aacgaagagg aaaaaagctc tatcgctaat cggtgcattt
    14581 gcgctgacat tttctccagc agtccagtgg tggttcatgc aacatgtggg cgatttgatt
    14641 ttctttactt tgggactgat gattgctttt tatcattatt tctacaatca tgataaaaaa
    14701 tggctacgaa cgttgatgat gcttttggtg gttattttcg gtattgggtt tattttagtg
    14761 atttacccag cccatcaagt gatgctggcg tacttgctga ttttttattt tgttggcctg
    14821 cttatttact atagcaagaa agtttcatgg gatctgttgg atgtagtgtt gattggaggg
    14881 gcagttttat ttattggcgg agtcatggtt catttctggc taacgtcaaa agacgcattg
    14941 ttagcttctt tgaatacctt atatccagga aaacgggtaa gtactggagg aaagtggacg
    15001 attggcgaat ttttttcttt ccttacaaat tggaaaattc cttttgaaga tatcaactat
    15061 tcgaataact ctgaagtggc cctgttctat cacttttttc caactgtatt cctagcaagt
    15121 ccatttgtgt tatttggcaa aaaagatagc gaacaaaagt tactgggacg tattttgatg
    15181 attttttgtc tgttttctat cttttggatt accgttgggt tgccaaaatg gctagcagaa
    15241 atcactctgc tgtcttatgt tcctccatta agagccatcc ttacttttag ttttgcggct
    15301 tgtttattat cgatctggtt tatcgcttat atttggagag aagatgttat tcctatttgg
    15361 tataaattca ttttgttggc agtaaatgca tggtcttatt tctatgcgat tacgcattcg
    15421 aaaatggata attatttttc ggattttgaa accatcgcag ttgctgtgtt gggaacagtg
    15481 attttagctt ttgcattatt tggctggaga cgcttgtttt acctcgcttt tgtcgcctta
    15541 gttatcgtat ctggcttttt cgtcaatcca gtcgtagaag gtacaggagc gatttttgaa
    15601 aaaacactgg caaaagaaat ccaaaaaatc gatcaacaag atcctggtaa agtttggttg
    15661 tctgaagatg aattatataa cttcacccca acattgggag tgaaatcctt caatacagta
    15721 cgcttttatc cagatatagc tgcatggaag aaaatcgatc cgaaagaaga atacgagaag
    15781 tattataatc ggtatgctca tacaagagct tttatcgcta aggaagatac aaagttcatt
    15841 ttagatcgtc cagatatgtt ttcggtcacg ttgaattttg aagacgcaga aaaattaggg
    15901 atcgactatg tgatcagtaa acgaccatta actgattaca accaattata tgaagcgcag
    15961 ttcacgcagc tatatggacc ggataaagac ggttatatga tttttaaagt agaatatccg
    16021 gattatccag atgtaccaca aacacaaact caggaaaatc agctagtcgt acagtaatag
    16081 gctagctgag aataatcctg aaatattagt agaaaggaga gtgaagataa ttcaagcaat
    16141 cgtacaaaaa tttgtcaaca aaatgagtgt cggtttcttg cttttgttgc tgacgctagt
    16201 cttttttgtt tggacagcag gggtaggttt tccagcaact ttgtttatat ataacaatag
    16261 ttcattactt atcgctttta gtgtggctat tttgctcatt ttaaatgttt ataaagcaaa
    16321 aggcgtcgat tttctttatc taggtgttgc gcttgccctt ttcattttct tttcttactt
    16381 tcgggaatta agaaatgagt ctttatttgg agacttactg tttcctttga ttattttatt
    16441 ttgtttagta attaaatgga tcgagtggac aaaatgggat cgcggtattt atctgattgt
    16501 ctttacggtc ttcctcggaa tcacgttata tcgtgtattt acagagatcc aagtaccaga
    16561 aggacaaagc atctgggctc caggcaattc gctttctgat atttggatca atacgaatac
    16621 aatcggaagt tctttgatga ctcttgcttt attgatcagt ggatttgcca gttcttttga
    16681 acgatggtat gttcgaatca tcggtgggat agcagtcgtt gcagcctttt taggtatttg
    16741 ggtctgccaa tctagaggtg cattagtcgc gttgattgtt tttgcgatat tggatctttt
    16801 acctaaatcg ttgatgcgtg tcattcgtgc gccatttatt gcctacacgg ttacgattct
    16861 tttagctttg ccgatttctt atctggcggc tgtctctgaa aaagtcaatt tgtttaccgg
    16921 tcgagaagat atttggcata aattctatca gacgctagga gaaaaatctg aacaagtttt
    16981 actaggaatg aaaacattta tcttccagcg aggaaaccaa tttttaggaa accacaatag
    17041 ttataattct attttgaata tctatggatt gataggattt gggattgctg ctttgctgct
    17101 tatccttttt attggtcgct taacgttgaa agcagattta tccaacgggc agatgacttt
    17161 tatctgggcc ttttttgcgg tgatgatgca gtcatttatg gaggatacat tgacttcata
    17221 cccatgggtt ccgattattt atatcctgtt ggctatggcc gttcatcgat atgatgaacc
    17281 agaagttacg gaggaattct atgttatgga agaggcatat gacgatatga cttatgatga
    17341 tacatcttat gaggaacaac cagatagcgc tcattcttcc aggatccaac gctatcattg
    17401 ataggcacaa aatacgagag aggctgtgac aaccgtcgca gccttttttg gtttattgca
    17461 attgtctagc atcttctgta aaatagaaac gttagagaaa atcttgtatc atagaaaatt
    17521 aagaaagaaa taagaacgca gctcggtacc aaaaatatgg taaaatggca cttgactgta
    17581 attcactgaa aatcgcttgg aggaacacaa atgtttaaag atttgtattt atttatgaag
    17641 gacatttatc agaacagaaa attactgcta cagttttcga tcaatgactt caaatcaaga
    17701 tatgcaggat cgtttttagg aatcttatgg gcgtttatca atccgctatt tactgtattg
    17761 atttattggc tggtatttgg tgttggactg aaagcacaaa tgatcgatgc aaaataccca
    17821 tttatcgtat atttagttac cgggatgatt ccctggttct tcttctcaga tgcatttgca
    17881 tcaactacgg ttgtttttcg ggaatatact tatttagtaa agaaagtcgt attcaatatt
    17941 cgtatcttgc ccacgacgaa aatcctatcc aatctgtaca cccatttatt cttcattctg
    18001 attggcatag ctgtcgcgct tataaatggt atatatcctt cagcaatgtc tttacagctg
    18061 atttattatt tattttgcat gtgtgctttc ttgacaggat tgacttggct gacggcatcg
    18121 atccaaccat ttttacctga tatcatgcaa ttaattacga tcgtgctgca gttgatcatg
    18181 tggacattac cgatattatg gagccctaat cagtttgatt caggtcttgt aagcatattg
    18241 aaattaaatc cgctgtacta tgttgttcaa ggttatcgtg agtcattttt aagtgaagct
    18301 tggttctggg agcatggaac atatactttg tatttctggg ttttcacgtt agtaatgttc
    18361 gtaatcggct ctgcagtgtt ccgtagattg aaaccacatt tttcagatgt gctgtaagga
    18421 gaatagctat gacagaatat gcaattagac taaaagatat cacaaaatct tataatatgt
    18481 acgcaaaacc ttcggatcga tttcgtgaag ccctcaatcc ttttaagaaa tcctatcatg
    18541 atgtatttta tgcgttgaaa aacgtgaatg tagaaataaa aaaaggtgag atgatcggtt
    18601 tcgtgggaga aaacggatcg ggaaaatcta caatgttgaa aatcattacg ggagtactga
    18661 caccaacatc cggcacgatg gaaatcgaag gaaaaatctc agctttgcta gaactaggat
    18721 caggattcaa tcctgagtat tctggctatg aaaatatcta tttaaatgga atggttctag
    18781 gattttcaag agaagaagtc gatgaaatgg tcgatgatat cattgaattt gctgacatcg
    18841 gcgaccatat ttatcaacct gtaaaaacct attcaagtgg gatgttcgtt cgtctagctt
    18901 ttgctgtagc gatcaatgtg aatcctgata ttttgattgt ggatgaagca ttggcagtag
    18961 gagatcttga atttcaacta aaatgtatgg aaaaatttac agaaatcaag aactcgggaa
    19021 agacgatttt attcgtttct catgatatta gttcgattcg ccgtttttgt gatcgttcct
    19081 attggttgaa aaatggaaaa gttgtcgaat atggtgatac gatggaagta acgacgaatt
    19141 acgaaaactt tttgaagaaa aaatcagtta aaacagtaga tcgaaataaa aaccaagtag
    19201 aacgcttcgc agctccagat atcgtagacg tgacgaaagc cgaattgttg gataaagata
    19261 aaaatccagt ggatatgctg gaacaaggag aaaaactata cgttaaagta acctatgaag
    19321 taaaagacga tacaatcaaa aatccagttt taggaattgc tctgcgtaca gtcgacaatt
    19381 tttatgtgtg cggactcaat actctactag atggtatcaa gatcccttgg aaaaaaggtg
    19441 agaatatctt ttatctggag tatgaaaagt taggtttgtt agctggtgaa tattattttg
    19501 acgttgcggt ctttgaagaa aatgcaacgg ttcctttggt atacaagaca aaatacatga
    19561 acttgtttgt cagcggttct tatatcggag aaggcatcgt ggtcttagac cataaatggg
    19621 aagaagggac tcatagcaat gaaatatgat tttgaaatgg acctagatga acaaagcagt
    19681 gtgggaaaaa ttgccgcaca gatcaaacca ggaagtaaag ttttagagtt tggtcctgga
    19741 aacggccgat taacgaaaca tttgatcgga gcaaaacaat gtgaagtgag cattgtcgag
    19801 ctagataagg aattgttcga ttttgtcagc gagtttgccc aagatggatt ttatggagat
    19861 atcgaaagtt ttgaatgggc aaactattat gctggacaaa catttgatta cgttttgttt
    19921 gccgatgttt tagaacattt ggtagatcct ggaaaaacgt tgaagaaagt tagagaattt
    19981 ttgaatgaag aaggagaaat tctaattaca ttccctaacc ttgcgcataa ttctgtcatg
    20041 attgatttgt tcaataatca attgccatgg gcttcttatg gtttgctaga tgaaacccat
    20101 aattcttttt atactcatga tggcttccaa aaagtttttg aaaaagcagg attatacatc
    20161 aatattgaag attatttgta cttagctgta ggtgatacag aattaaaatc aacttatgaa
    20221 gaattgccgg aagctgtacg ttatgatttc aaaatgcgac catttggcga agtctaccaa
    20281 tacttcttct cattgatgaa acatccagta gcacaaagtt ccattgcgca gccgcaaaat
    20341 tctaattatg tgaaagtatt agaagtaatc cagcaaacga aacaagatga aataattcaa
    20401 caaataccat tcaataattt cacaggggaa aatgagacac taagtttcca tgtatcagaa
    20461 ttagcagaac gaatggtgtt tcgcttcgcg cagcaaccta gctttatcga attcagcgca
    20521 gaagctgctg gagaaaaact cacatttatc gattcaaatg ctgtagtcaa aacagtaaat
    20581 gattgttatt tgtttgatgg taaagattta ccagagttct ttttaacgga tattgcaggg
    20641 aaagaagtga ctatccattg tcactatcgt tttatcggag aattgacacc aacaatgaaa
    20701 gaattgctgg aaacaatccg tccaatggct gaagttacaa agcagctttc tgagaaaaat
    20761 gatgaattag aaagagaaaa tcattatctt attgagaata atacaagatt agatcagacg
    20821 ttgaaaacaa ccataaatcg ctattgcacg ttgttggaaa gtgatgaatg gacaatcaaa
    20881 catagattag ggcgacgtaa gaaagaaaca tcgaaaaaaa tccaagaaaa agagctttct
    20941 ctatgtattg acgaaaaaat ctgggatgca gaaacaaaga tattgaaaat catcgggtgg
    21001 ggaatcgcta attcggatcg ccaaccattg tcctataagt tatcagccga ccaatcacca
    21061 ttttttgaag caattcctgt tttacgagaa gaagtcaatc aagcaaaaca gctagctgaa
    21121 ggagcaaaag caggatttga actgcggatc ctttgcgaga aggaacgttc attcttagtt
    21181 gaagcagtgg ctcaaaatgg tcaatcatgg atcattgaaa tgtaaataat gattaactta
    21241 taaagataag gagtaaacga atcgtgcaaa aaaaagaaat tgccgtattt atcgatcaaa
    21301 tcactcgtga acgggccact ggcgatttgc ttattgtggg ctgggcaatt gatgaagtga
    21361 ccaaagaaat ccctacgata aaggtagaaa aagaaaatgt gattgctgaa gcaacacatg
    21421 tcgtaagatt ggatatcaat catttatata atcttgatgt taagacccaa agcggtttta
    21481 aggtacgttt atcagggaaa atgagaggaa aagcaatctt agacttccaa acagcaagac
    21541 atcaaaatgg catagctgtg aaattaaacg gtaaatatcc ttatgatgac ggcattgaat
    21601 cttcatggga aagaaaaaaa agattactga aaaaagggat aaattatgca aggactcatg
    21661 gcgtaaaaaa agcaatccgc cgggtcaaac tggaattgaa accaggatcg atcgactatg
    21721 cagagtggat cagtcgtcat gagaaacctg atctgaaaga gcaaaggaaa gaagtacaag
    21781 gatttgccta ccgcccattg atttccatac ttatgcctgt ctataacgtt gaaatcaaat
    21841 ggctcgaaaa atgcattgat tcggtacttg atcaaacgta tgatcactgg gaactatgta
    21901 tcagtgatga tgcttctact gatccagcta tccgaaagtg tctagaatcc tatcaagcaa
    21961 aagatgatag aattaaagtc gttttccgac aagaaaatgg acacatcagt ctggcaacta
    22021 attctgcatt gaaaatggca gaaggagagt ttatagcgct cttagataat gatgacgaat
    22081 tacctccatt tgccttatat gaagtggcaa aagtgctaaa cgtacatcca gaactggatt
    22141 tgatctacag tgacgaagat aaaatcgatg cagatgggaa tcgctttgac ccgcacttca
    22201 aagcagactg gtctcccgat acattgatgg gaaataatta tatctctcac ttaggcgtat
    22261 atcggacaag cattgttaag gaacttggcg gtttccgtaa aggatatgaa ggctctcaag
    22321 attatgattt ggttcttcgt gtgacagaac aaattcctgc agaacacatt taccacattg
    22381 accgtgtctt gtatcattgg cggacgatcc cgggatcaac tgcaagcaat ggagaagcta
    22441 aaagctacat ctatgattct ggagtgaaag cattgacaga tgctctatct agaagaaata
    22501 tcaagggaag cgtacatcct ggcagaattt ctggttttta tgaaatcact tatgatgttt
    22561 tgcaagaaga cttggtcagt gtgatcattc caactaagaa tggctatgaa gatctaaaaa
    22621 cttgtgtgga ttcgatcatc gaaaaaacgt cttatccaaa ttatgaaatc attattgcag
    22681 ataatggaag tacagatcct aaaatgcaag aattatttgc agaatacaag catcagctga
    22741 aagaccgatt tatcgtcgaa ttaattgaca ttccattcaa ttattcacgt atcaacaatc
    22801 tggcagcaga aaaagcaaac ggcaaatact ttttattctt gaataacgat acagaagtga
    22861 ttgaacctga ctggatgaca gcgatggttt cttatgcaca gtttgatcga atcggctgtg
    22921 taggagcaaa attattttat ccggatgata caacgcagca tgcaggtgta ttattaggga
    22981 tcggtggcgt tgcaggacat gcattgaata actatgatcg aacacattgt ggttactttg
    23041 gccgattggt cattgacgtc aattacttag cagtcactgc agcttgtatg atggtcaagg
    23101 cagctgactt caatgctgtc aatggatttg atgaaatatt agaagtagca ttcaacgatg
    23161 ttgacttgtg cttgaaagtt tatgaactgg gtcgttacaa tgtctatgca catcaagcag
    23221 aattgtacca tttcgaatct aaatcaagag gttatgaaga tacaccagaa aaacaaagac
    23281 gttttgctgg ggaaatcaaa aaaatgcaag ataagtggcc ttcttatatt gctcatgacc
    23341 cattttataa cgataatcta actaaagaag gaatcggcga tttttcgttg agacctgatt
    23401 gattaaaaga actgtatttt catttttatt aatgaaaata cagttctttt aatttaa
//
LOCUS       DAIGTA010000046        23071 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.047, whole genome shotgun sequence.
ACCESSION   DAIGTA010000046 DAIGTA010000000
VERSION     DAIGTA010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.047"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(186..1223)
                     /locus_tag="NOB43_001913"
                     /pseudo
     CDS             complement(186..1223)
                     /locus_tag="NOB43_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355588.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(1460..2479)
                     /gene="ptcA"
                     /locus_tag="NOB43_001914"
     CDS             complement(1460..2479)
                     /gene="ptcA"
                     /locus_tag="NOB43_001914"
                     /EC_number="2.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine carbamoyltransferase"
                     /protein_id="HCI0982767.1"
                     /translation="MGKKDFITTENYTKEEIQQIVDLSLKIKAAIKNGFYPPLLKNKV
                     LGMIFQQSSTRTRVSFETAMTQLGGHAEYLAPGQIQLGGHETIEDTSRVLSRLVDILM
                     ARVERHHSVYDLATNATIPVINGMSDFNHPTQEIGDLCTMIEHLPAGKKIEDCKVSFI
                     GDATQVCFSLGLIATKMGMEFVQFGPEGFQLNEDHRARLDAICKDSGGSYTISDQIDV
                     IEGSDFVYTDVWYGLYEAELSEEERMRIFYPKYQVNTDLIKRAGKQAKFMHCLPATRG
                     EEVTDEVMDGPNSICFDEAENRLTSIRGLLVYLMRDYAEKNPIDETKKAAAKKDLEAL
                     LGETF"
     gene            2805..3686
                     /locus_tag="NOB43_001915"
     CDS             2805..3686
                     /locus_tag="NOB43_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0982768.1"
                     /translation="MTFAIYAYLKEKNNLFLWISLYLAFFIFDNTIIYMTEFLNSFAQ
                     SYDQVFMSAPAVKTIIFMGNAFFSISILAELQKEKLSPLHYALLLALAVWMITIPLMD
                     NSAFKVWLYYLGNQLFLFYLGIYCWRGTKKDVPLLNKHYLKQLMFINLFFSILIIIED
                     SFVIFNVDQYSSLVTKIYNRSVSEDIFSIVICVLLLHFFIKKYQPQKEKTQKQDTSLL
                     IQDFCQDHQFTQRETEIFILLLSHRTNQEIADQLFLSLGTVKTHVHNIFIKLDIKKRT
                     QIIPLFEKYKEAIESTV"
     gene            complement(4159..4563)
                     /locus_tag="NOB43_001916"
     CDS             complement(4159..4563)
                     /locus_tag="NOB43_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI0982769.1"
                     /translation="MGKQLVLISHGLFCEELKKSTEMIMGPQESIHTVSLLPSESAED
                     FREKFETVIANLDDFVVLADLMGGTPCNVVSKIILEGQVIDLYAGMNMPMVIDFINSQ
                     LIGTELSLIESATSNICYVNGRIFSDDDDEDE"
     gene            complement(4601..5410)
                     /locus_tag="NOB43_001917"
     CDS             complement(4601..5410)
                     /locus_tag="NOB43_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0982770.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKLYGDNSPELKEMMKTHTQFFNTSNFFNTIVTGIDLAIEEKEGIDGKDTVSGLKA
                     GLMGPFAAIGDSIFAALIPTIFGALAANMAINGNPTGIFIWIIAQIAVMIFRWKQLEF
                     AYREGISLVTTMQHRLTALTDAATLLGVFMVGALVATMINVKLSWAPSIGDVTLNMQN
                     NLDMILPRLLPAGIVAAIYWMLGKKNMTSTKAIFIVLVVCVALSALGVISK"
     gene            complement(5397..6293)
                     /locus_tag="NOB43_001918"
     CDS             complement(5397..6293)
                     /locus_tag="NOB43_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0982771.1"
                     /translation="MDILWWQILLLTLYAGYQILDELQIYSSLSAPVFAGLFAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSVALGMNPEQAIAVIAVP
                     VASLMIQLDILARFANTYFAHRIDKLVEDMNYKGIERNFLMGALSWSLSRMIPVFLAL
                     AFGGGLVEQVVVVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHFPYLILGFT
                     LTALLGTVFTNMQVLGTGVAGAVKNFEGIFNSLPMLAIALVGFSLAAISYKNGQLIPH
                     SPAPKDVTSNDSDEGEIEDDEI"
     gene            complement(6306..6785)
                     /locus_tag="NOB43_001919"
     CDS             complement(6306..6785)
                     /locus_tag="NOB43_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HCI0982772.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNITRIMVVDDEVAKNDIEK
                     SGLKLATPPGVKLSVLPIEKAANNILAGKYDSQRLLIIAREPDRLLKLVELGVPIEEI
                     NVGNMSQTNETRSITKSINVVDQDVEVFNKLQAKGVRLVAQMVPSDKAENFMALLAK"
     gene            complement(6789..8567)
                     /locus_tag="NOB43_001920"
     CDS             complement(6789..8567)
                     /locus_tag="NOB43_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HCI0982773.1"
                     /translation="MNTFEIKEDFLLNGKPFKILSGAIHYFRVDSADWYHSLYNLKAL
                     GFNTVETYVPWNLHEPKKGDFHFEGILDLEHFLSIAEELGLYAIVRPSPYICAEWEFG
                     GFPAWLLNEGTRIRTNETVYLNHVADYYDVLIKKIVPHQLTNGGNILMIQIENEYGSY
                     GEEKDYLRSIRDLMLDRGITVPFFTSDGPWRATLRAGSMIDEDILVTGNFGSKAEENF
                     SSMEAFFNEHGKKWPLMCMEFWDGWFNRWKEPIVQRDAKELAEAIKEVVLRGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLDEQGNPTEKYYAIQTMIHETFPDIQ
                     QMEPLTKDTMEMKDIPLIDKVSLFSTLDTISQSVKMKYPETMEMLGQNTGYILYRTSI
                     KKDAEHERLRVIDGRDRSQLFLNQKLQATQYQTEIGEDIIVPMPQEDNQLDILIENMG
                     RVNYGHKLLADTQKKGIRTGVMADLHFITDWNQYCLPLESCEKVDFSKEWHPNQPSFY
                     RYEVTLDEVEDSFIDLSKFGKGVVFVNQTNIGRFWEVGPTLSLYIPKSLFKKGNNEIV
                     IFETEGTFQPEIQLVKAPLYKEMKEG"
     gene            complement(9401..10339)
                     /locus_tag="NOB43_001921"
     CDS             complement(9401..10339)
                     /locus_tag="NOB43_001921"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HCI0982774.1"
                     /translation="MIVTVTMNPSIDISYPLASLNVDTVNRTDQVSKTAGGKGLNVTR
                     VIHDLKGDVLATGVLGGYHGAFIADELKHAGIKQKFTDIKEESRDSIAVLHEGNQTEI
                     LEAGPTVSYEEQQNFLENFKELIKKAKIVTISGSLAKGLPSNFYQTLVQLTEEQSAKV
                     LVDTSGESLHQVLAGKQKPFLIKPNLEELSTLLRHSFSIDRLEEVQEELIQPIFAGIE
                     WIIVSLGKAGALAKHKDCFYRVTLPTIKAVNPVGSGDATVAGFAYGLSQEMDEIELLK
                     FCMATGMANAQEGQTGHVSPVNIQSHIEKITVKKIE"
     gene            complement(10351..11358)
                     /gene="lacD"
                     /locus_tag="NOB43_001922"
     CDS             complement(10351..11358)
                     /gene="lacD"
                     /locus_tag="NOB43_001922"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI0982775.1"
                     /translation="MITLTRGKKAAMDRLSTKDGIISALAIDQRGALKKMIKALNVEL
                     NDEQIERFKELVSSELTPYASSILLDPEYGLPAASARHEDAGLLLAYEKTGYDVTTPG
                     RLPDLLADWSVLRLKEQGADSIKFLLYYDVDEDPEINHQKHVFVERLGSECAEEDLPF
                     YLELLSYDTQISDVHSLEYAKVKPHKVNSMMKEFSKPQYKVDVLKVEVPVNMNFVEGF
                     STDEVAYTEEEAAKYFLEQSQATDLPFIFLSAGVSTKLFQQTLFFAKDSGSTFNGVLC
                     GRATWKNGVKPFIKSGEESARAWLKSEGRENIESLNNVLAQTASSWYDKVQVEKEAAV
                     N"
     gene            complement(11381..12553)
                     /locus_tag="NOB43_001923"
     CDS             complement(11381..12553)
                     /locus_tag="NOB43_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0982776.1"
                     /translation="MFTVGKEKLDQLGAEITTREIRQQPELWEETLDHYQTVQKELDN
                     FLAIVKEKANGQRTRVIFTGAGTSQYVGDTLVPYLRKNGDRQAFSFESIGTTDIVAEP
                     EEYLIKEDPTLLVSFARSGNSPESLAAVEIANQMVDTIYHLSITCAVEGKLAQISQSD
                     SNSFLFLMPARSNDSGFAMTGSFSCMTLGALLTFDQTVLVKKQQYLKVLNNLGNEVIT
                     RVNEIEKIVQLDFERIVYVGSGSLAGLTREAQLKILELTAGKIATIFDSSMGFRHGPK
                     SFINQKTIMFGFVNNNPYTRDYDLDVLEEVRGDEIASGVFAITQPGQRNFTGDKFEFT
                     TEAELLPDGYLALSYIMVAQIVALLSSIKVNNKPDTPSPTGTVNRVVKGVTIHKYK"
     gene            complement(12566..13297)
                     /locus_tag="NOB43_001924"
     CDS             complement(12566..13297)
                     /locus_tag="NOB43_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0982777.1"
                     /translation="MGNSFKNKALYHQLVDLLKNQMESNMIPHDKLPSERELTAQYGV
                     SRTTVRLALKELENTGYIYRRHGKGTFVSDIKKNVADLAGTYSFTEQMKSLGRTAETR
                     ILAFEKIEADKFIAKQLNLSLGEVVFKLSRLRIADREPLMIEDTYLPVKFFLSLNDQL
                     LRSKPLYDLFSEDFNQTVRLADEELYASVASKEDAKQLIISEGAPVLHLARQTYNMKN
                     EIIEFTLSVARADQFHYQIRHIRNS"
     gene            complement(13552..13740)
                     /locus_tag="NOB43_001925"
                     /pseudo
     CDS             complement(13552..13740)
                     /locus_tag="NOB43_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(14086..14775)
                     /locus_tag="NOB43_001926"
     CDS             complement(14086..14775)
                     /locus_tag="NOB43_001926"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0982778.1"
                     /translation="MEKNKQKLTTAIYKLNEKNQLLGQLSGLTSDFISETGIETKRSE
                     QAKVKKIYDHLSRKVQELKELKDSKLTEIKKQIKSTFNLYTVNQIFQMIEPHPDFRKI
                     SFKINEANPDKLGLDIMCKRTEDEEDAPILYLSSAQVNILSLSIFLGTALENTDKVNT
                     IFMDDPIQHLDSLNELSFIDLLRILAFKLGTQIIFSTHNRQFFDLCQRKLDANYHNAS
                     FIEMNYTENQL"
     gene            complement(14922..17198)
                     /locus_tag="NOB43_001927"
     CDS             complement(14922..17198)
                     /locus_tag="NOB43_001927"
                     /inference="COORDINATES: protein motif:HMM:NF024867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0982779.1"
                     /translation="MSLKLKGIKIDSFRAFERQKYFDCVNPVFNEISNLIVLYAPNGT
                     GKTSFFDAIEWSLTGEISRLNENKNVRDIASQERKYILKNKYSSAEVDSVELAFDDGS
                     FYALTTKRLNGKQTTDYVEGNETKKTVDLTAKELKILRQKNLLTHNQIDAFLRSQSAE
                     GRYDALSNFWDKENVSEDYKNLVLFVNEMNKVLGQQETKMNQLTKEIEKLESNAKIWQ
                     TINQLKENYAKLNGKNSKKDPLLKNQLGLQELYIESNKLKSNNQIKLNQFEEERQQLE
                     NLITMIQEYRQIPQQIEWSEKQVADVNEKLAHLTEIETIEEKKKALFDEKIDLSNHLK
                     RCNFLINHEADFQALEMAEQNSNREINEWINQRKKCEQALITLQKEHQEQEVTLSECQ
                     NKRALRTNQLTEIKELNSYSDVKAKRQLLDHEIKQQKKKKIGLEAKLGKIKLTLTKLF
                     SLLNLDDHQLSQKDYSKDPDYSFLLEQISQLDDIWQERKKLEVDLTQKKKERSSLEDL
                     GSQLEQLKKLGYSIVTDTSSSVCPLCLHDHQEFQHIIQKIEASTADLLPIEQLTKEIS
                     HLEGMIDESTRRLTEVVSGVKQQIQIQITVKETEINQLDQDLLQVTLKLKQQEEAYLT
                     NEKHWYKLNEYSQKYGIDCEKIAEETQKRVKSLQEELVKLTNEYQNIKEKINQNEQLN
                     VKNTHTLKTIELHYQQAKKSLNDLKGNEQYQHYQQEQAFYEALGISVISDFKRQCKRE
                     LEKINEQETKLIAEKNND"
     gene            complement(17188..17802)
                     /locus_tag="NOB43_001928"
     CDS             complement(17188..17802)
                     /locus_tag="NOB43_001928"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982780.1"
                     /translation="MVEILKEITTYEIIEKTTGLTCYTYQQANEKYRLHFFCYVFDNQ
                     DELLANYEEINDQIAYSFQSQLKRKIERWNIYFFLFVKAKVAKPIKASIEQDKYATRK
                     VIVDNFREFATNDAQKEAQKEAQKEAQKEAQKNKIQKRLLLNLEQTKPVKKLAKDERQ
                     NDEKIIHLLAELKTMAKKEKKARIQEYIKHELSNLNVKEGTDES"
     gene            complement(17818..18657)
                     /locus_tag="NOB43_001929"
     CDS             complement(17818..18657)
                     /locus_tag="NOB43_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982781.1"
                     /translation="MYVEREGKCYLTGIITKLQSAGQQGIVEGIHIAHIVAFFLEEFD
                     IMLVPRCLNDFSEYLASIINELREVGGQENKLIFLIEKCYRECFSDITPKLIHNRLSD
                     YLFLPSQKNEDYTNKFLWIAWLEILLYKLLQTNIAFEIDDCFKLLTQEKERAGIHVLF
                     TNHLTLDRFIGSLFRSTLYDKLDKQDVLFVTNQRRKFRGGSIAKREQIEGIVVNIDHP
                     EVSDRLTIDNPNEKKLFPIVHVDYIENEIDQILHDTKGLTAVEFSQRFPEELTRLFEE
                     IAN"
     gene            complement(19110..20204)
                     /locus_tag="NOB43_001930"
     CDS             complement(19110..20204)
                     /locus_tag="NOB43_001930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982782.1"
                     /translation="MQGQDCNEREMITVKALPAYDGDCLIVQYGEEDQRTNLFVDGGQ
                     GQQVVRQLKEEIATISQKGECIDLLVLTHIDADHIRGFLSLFSQSSFDKSCIKRVFFN
                     SRKLLSQKFDTKVVYDDQLEIVQEKSEISFKQGESFDRYLENLRIEKMTVIDNSCQPK
                     LLNGAKMTILTPDEASLRKLYTDWEKAIQKETRDQLISGRNVNHQGSVEELIKKAFQE
                     DRAVANGSSISFILEYEGKRLLMLADAHPSTVTAKLKELYGEKELHFDLVKVAHHGSK
                     ANTSDDLLKQIECENYLISSNKGNRHGFPHKEALSRIVYHNYTKKRPTNFYFNYSDAS
                     EGLFTNEEIKKYGIQLIKKKMNERVLTIDI"
     gene            complement(20623..21033)
                     /gene="arsC"
                     /locus_tag="NOB43_001931"
     CDS             complement(20623..21033)
                     /gene="arsC"
                     /locus_tag="NOB43_001931"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HCI0982783.1"
                     /translation="MKKIYFLCTGNSCRSQMAEGYARQLLSASDVEIKSAGIETHGLN
                     PRAVQVMAEDGIDISNQTSDLIDQDYFTQADLIITLCGDAKDKCPTIPVGVQHIHWDL
                     TDPAQAVGTEAEITSAFRKTRDRIKAMVIELKNQ"
     gene            21587..22150
                     /locus_tag="NOB43_001932"
     CDS             21587..22150
                     /locus_tag="NOB43_001932"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982784.1"
                     /translation="MFGFIALMFFLPLTKTHADVTVTNDCTDPSHSFTASINADNGKD
                     VSSDYYKVTVGQTESWRRNDPRGHILAIVYLEQLRTYYTPTNAAYSFKDGKLYSQGST
                     TEITPLKVETNSLVTRSMNVNMINLSTSLTTVSLSKWKSGGSTDYFALNHLDSETWSR
                     NDDPRGFLVSVLYNGGFSKEYIYYLPI"
     gene            22222..23071
                     /locus_tag="NOB43_001933"
                     /pseudo
     CDS             22222..23071
                     /locus_tag="NOB43_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341471.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         6864 a         4753 c         3673 g         7781 t
ORIGIN      
        1 tattttttaa tctggcaaag gtaatgcttg cattcggcga catcagttag acaacatcga
       61 tgatcagtga tagaagcagt ttatctatac aaaaaaagaa gcagcgaaaa gctgctcctt
      121 aagataatag gtaaaattgc tgatatattt gacgattaac ctcttgaacg tcccaagaaa
      181 aatgatacta cagcaacaac gatgatcgca ccaatgatag aagcaacaat accattcata
      241 atcgccgcac cagtaggcat gccgtttttt ttgctgcgtt tggcaaatac tttcggcata
      301 tcgtcatttt cggctgcata acaagcagta ttgttaaccc ctaacgacca agaaatcata
      361 ttgccaaaca atgtcagtaa gaataaaaag gccatcgaaa taatgaacca gccgcctgtt
      421 gatcctgtca ataacttaaa actatccatc aatccactgc ctgtactaat ctgatccgta
      481 ggaattgcta caccgatccc gaatgcagaa aaaatgtaaa tagctgcaat caccagtcca
      541 ccggcaatga tcgattgagg gatttgcttt ttaggatttt ccatatcatt cgcgaatgta
      601 caaatcactt cgaatcctaa taagttaaaa atgattactg aaataaagga caaactattt
      661 aaattgaaac ttggcagcat ggaagaaaga gtaaactcat tcgccacacc cttagtaaac
      721 gcagtataga gacctaagcc accaatcaag attgccagca gcattttgat aacagctgct
      781 ccattcaaaa tccacacact gtcactgacc ggataaaaac tgatccaaac aatgatccat
      841 ataaagatca gttcgatcat gatagcagca gctgttgaaa attcgctgcc tgtgatcgtc
      901 atcaataaat cagggcagac tactgctaga gaagctaacc acagtggata attaatccag
      961 taataccaag aaacgcgaga tccccagcga tgtccgaagg cttgtgtcac ccaatcatag
     1021 ataccgccat caccgatata agttgttcct aactctgacg agatcaatcc atagggcaaa
     1081 aggaatgcaa tcaataaaaa gatccaccaa aaaaattgtg aatttccgat tgctgctacc
     1141 ggtgcagccg cttctgccac aaatacaaca caaataacag ataatatagc actcatcaaa
     1201 ctaaattttt tcttttctcc cattgttttc ttcctttccg gtacaaggga ataaggttgg
     1261 accagcgatt gaacgattct tgtaacctgc ggactcacct cgtatgattt ctagtgcggc
     1321 ataaaagcta cattagtgtg agatcaagat tctgctagaa agaatcgatt ttcagatcgt
     1381 tagcccctcc tctagaacag agacaatcct cacgcatcgt catgatacgc agattatttc
     1441 ctttcctcat ctcttgcgtc taaaatgttt cacctagcaa agcttccaag tcttttttag
     1501 ccgctgcttt tttggtctca tcgattggat ttttttccgc ataatctcgc atcaagtaca
     1561 ctaagagacc gcgaatcgaa gtcaaccgat tttctgcttc atcaaaacag atcgagttcg
     1621 gtccatccat gacttcatct gtgacttctt ccccacgagt ggcaggcaag cagtgcataa
     1681 atttcgcttg tttcccagca cgttttatca agtccgtatt cacttggtat ttaggataaa
     1741 aaatacgcat gcgttcctct tctgatagtt cagcttcata cagtccatac caaacatctg
     1801 tataaacaaa atccgaacct tcgataacat cgatttgatc ggatatcgta taggagccac
     1861 cagaatcttt gcaaattgcg tctagtcgtg cgcgatggtc ttcgtttaac tggaaccctt
     1921 ctggtccaaa ttgaacgaat tccattccca tttttgttgc aatcaatcct aaagagaaac
     1981 agacttgtgt ggcatctcca ataaaggaaa ccttgcagtc ttcaattttt ttgcctgctg
     2041 gaagatgttc gatcatggtg caaagatcgc caatttcttg cgttgggtgg ttgaagtcag
     2101 acataccgtt aataactggg atcgtggcat tcgttgctaa gtcatacaca ctatgatgac
     2161 gttccacacg agccatcaaa atatcaacta aacgagaaag aactcggctc gtgtcttcta
     2221 tcgtttcatg accacccaat tgaatttgcc ctggtgctag atattctgcg tgtcccccta
     2281 attgtgtcat tgctgtttca aacgaaaccc gcgttctggt agaagactgt tggaaaatca
     2341 tccctaacac tttgttcttt agcaaaggag gataaaaacc attcttgatg gccgctttga
     2401 ttttcaatga caggtcaaca atttgttgaa tctcttcctt cgtgtaattt tcagttgtaa
     2461 taaaatcttt ttttcccata atggaacctc ctaagtaatt tgtttgcttt gcatcttcac
     2521 tttaggaaaa aaagtgagag tttacgataa gttattagtt gtaaacgtta tcattgccga
     2581 tctatacgtg ctacaggctg gtttattttt ggatataaac catttatttt ccaagggttt
     2641 acaaaagttt agaaggaagt ttataggaat taaaagtaaa gataaaaaaa tcggtgttat
     2701 aattaaaata agaaatttga ggtaaggaaa aaaatgaaag gggattcaat acgatagcta
     2761 tttttgttta caacattcta ttgatcattc tatattcaat cacgatgact tttgctattt
     2821 atgcttattt aaaagaaaaa aacaacttat ttctctggat cagtttgtat ttggcattct
     2881 tcatttttga taacacgatt atttatatga cggagttcct caattccttt gcacaaagtt
     2941 atgatcaagt atttatgagt gcgccagcag ttaaaacgat tatttttatg ggaaacgcct
     3001 ttttttccat ttctattctt gccgaactac aaaaagaaaa actttcccct ctccattatg
     3061 ctttactgct tgctttggct gtttggatga ttaccatccc actgatggat aattcagcct
     3121 ttaaagtctg gctctattat ctgggcaatc aactcttcct gttttaccta ggaatttatt
     3181 gttggcgagg aacaaaaaag gatgtacctt tgctgaacaa acactattta aagcaattga
     3241 tgttcatcaa tctcttcttt agtattttga tcattattga agatagtttc gtgattttca
     3301 atgtcgatca atatagctcc ttagtgacaa aaatttataa tcgtagtgtc tcagaggata
     3361 ttttttcgat tgttatatgt gttttattac tgcacttctt tatcaaaaaa tatcaacctc
     3421 agaaagaaaa aacacaaaag caagacacct ctctcttgat tcaagacttt tgtcaggatc
     3481 accagtttac tcaacgagaa acggaaattt ttatattgct actgtcacat cgaaccaatc
     3541 aggaaattgc tgaccagctc tttctttcat taggaacggt taaaactcat gtccacaata
     3601 tttttattaa acttgacata aaaaagcgca cgcaaattat cccccttttt gaaaagtata
     3661 aagaagccat tgagtcaacc gtttaaaaaa gtcctggaag tatcccttcc aagttctcag
     3721 tctgtagacg agtctgggat attaatcaga aaaaatctaa ttaatgtccc acttttttat
     3781 gaggttaatc ataaaataaa aaaatggaga atgagacaaa agcggcatct tcaaaaattc
     3841 gctgaaattt ataaaaaatt tgagacacac caagtagata ataatcaaca ccaaaaaaaa
     3901 gtatttatgt ttcttgtcaa atttcggaaa ttccttctta ttccttgatg ctgaacattt
     3961 ttttctcaat ctttcaccaa tcattctaga atttctcttt accaacatca tttgacaaag
     4021 ggtctctttt ttgtccaaaa ttttgaacaa aactagataa aaagacattc caaactcaaa
     4081 ttacaagttt gaaatgtctt ttatctatag tatgatcaga gaaatatttc tttggcttca
     4141 tcactcatat attttatctt actcatcttc atcatcgtca tcactgaaaa tccgtccatt
     4201 cacataacaa atgttacttg tagcagattc gattaatgaa agttctgttc caattaattg
     4261 actgttaatg aagtcaatca ccattggcat gttcatgcct gcgtataagt caattacttg
     4321 accctcgaga attatttttg aaactacatt acacggagtg ccacccatta aatctgctaa
     4381 tactacgaaa tcatctaaat tggcaattac tgtttcaaac ttttcacgaa aatcttccgc
     4441 tgattcagaa ggaagaaggc ttactgtgtg aatactttcc tgaggcccca ttatcatttc
     4501 tgtacttttt ttcaattctt cacagaaaag tccatgacta attaaaacta attgttttcc
     4561 cattgaacca ctcctcatca ctaattggaa tcagcctgac ttattttgaa atcacgccta
     4621 aagctgataa tgctacacaa accactaata ctatgaaaat tgccttagta gaagtcatat
     4681 tctttttgcc aagcatccaa taaattgctg caacgatacc ggctggtaat aatcgtggta
     4741 aaatcatatc caggttattt tgcatgttta acgtcacatc accaatactc ggtgcccaag
     4801 acaattttac attaatcatg gtagcgacca acgctccaac catgaagacc cctaacaaag
     4861 ttgcagcatc tgtcaaggca gttaagcgat gttgcatcgt ggtaactaaa gagattcctt
     4921 cacgataagc aaattctaat tgtttccaac ggaaaatcat aacagcgatt tgtgcgataa
     4981 tccaaataaa aattccagtt gggttgccat taattgccat attggctgct aaggctccaa
     5041 aaattgttgg aattaacgct gcgaaaatcg aatcaccaat tgctgcaaaa ggccccatca
     5101 acccagcttt taaacctgag acagtgtctt taccatcaat accttccttt tcctcaatag
     5161 ccaagtcaat cccggtaacg atagtattga agaagtttga tgtattaaag aattgtgtat
     5221 gagttttcat catttctttt aattcaggag aattatcacc ataaagcttg cgtaattgcg
     5281 gcagaattgt ataaagatag cctgatcctt gcatccgttc atagttccag cctaattgga
     5341 aagtaaacaa gcttctgcga ttgatctgct taaagtcttc cttcgttaac ttataattag
     5401 atttcgtcat cttcaatctc tccttcatct gaatcattcg atgtaacatc tttaggggct
     5461 ggcgaatgtg gtatcagctg tccatttttg taactgatgg ctgctaaaga aaatccaact
     5521 agtgcaattg ctaacattgg aagtgaatta aatattcctt cgaaattctt cacagctcct
     5581 gcaacacccg ttcctaaaac ctgcatgtta gtaaagacgg ttcctagtaa tgccgttaat
     5641 gtaaatccta aaattaggta agggaaatgc tttttaactg gcaagtaacg tagtagaata
     5701 gcaaaaccga cagctggtaa aactgctcca gctactgata atccatcgcc taaccacttc
     5761 aaatcaccat ttagcacgac taccacttgt tctactagtc ctcctccaaa tgctaatgct
     5821 agaaaaacgg gaatcatacg agaaagtgac caagagaggg ctcccattaa gaaattacgt
     5881 tcgatccctt tatagttcat atcttcaact aatttatcaa tgcgatgcgc aaaatacgta
     5941 ttcgcaaaac gggctaatat atctaattga atcatcaagc tagctactgg taccgcaatt
     6001 acggcaattg cttgctctgg gttcattcct agcgctactg agaaagctgt cgctaaaatc
     6061 gttccagagt tggcatcaat ttttgatgcc cccccaaagg taccaacacc aagtacagtc
     6121 aattgcatac taccaccaat aataagtcct gcttttagat ctcccatcac tagaccagca
     6181 aataatccgg caaaaacggg tgcactcaac gatgaataaa tttgtaactc atctaaaatt
     6241 tgataccctg cgtataatgt taataataag atctgccacc ataagatatc catttattta
     6301 tcctcctatt tcgctaataa agccataaaa ttttctgctt tatcacttgg aaccatctgc
     6361 gctactaagc gaacaccttt agcctgtaat ttgttaaata cttctacatc ttgatcaacc
     6421 acattgattg atttagtaat ggaccgtgtt tcatttgtct gtgacatatt cccaacatta
     6481 atttcttcaa ttgggactcc taattctacc aacttcaata aacgatccgg ctcccgagca
     6541 ataatcaata atcgttgaga atcatatttt cctgctaaaa tattattagc agctttttca
     6601 atcggcaata cacttaattt aactcctggt ggagttgcca gctttaatcc acttttttca
     6661 atatcatttt ttgcaacttc atcatctaca accataatcc gtgtgatgtt caacttggtt
     6721 gtccataagt tggctacttg tccatgaatt aaacgtccat caattcttac tccgataata
     6781 ctcattgttt atccttcttt catttcttta tatagtggtg cttttactaa ttggatctct
     6841 ggttggaaag ttccttctgt ttcaaaaatc actatttcat tgtttccttt tttaaataag
     6901 cttttcggaa tatatagcga aagtgttggc ccaacttccc aaaaacgtcc aatattggtc
     6961 tgattaacaa atacgacacc tttcccaaat tttgatagat caatgaagct atcctccact
     7021 tcatcaagtg ttacttcata gcgataaaaa cttggctggt taggatgcca ttcctttgaa
     7081 aaatcaactt tctcacatga ctctagtggt aaacaatact gattccaatc agtgataaaa
     7141 tgtagatcag ccatgacccc tgtacgaatt cccttttttt gtgtatcggc taataattta
     7201 tgaccataat taacgcgccc catgttttca attagaatat ctaattgatt gtcttcctga
     7261 ggcattggaa caatgatatc ttcaccaatt tctgtctgat attgtgtagc ttgcagtttt
     7321 tgatttaaaa atagttggct acggtctctt ccatcgatta ctctcagtct ttcatgttct
     7381 gcatcttttt ttattgaggt gcgatacaga atataacctg tattttgtcc taacatttcc
     7441 atcgtttctg gatatttcat ttttactgat tgactaattg tatctaatgt tgaaaataaa
     7501 ctgactttat caattaatgg aatatctttc atttccattg tgtcttttgt caaaggttcc
     7561 atttgttgga tatcagggaa cgtttcatga atcattgtct ggattgcata atatttttcg
     7621 gttggatttc cttgctcgtc taagggtgct ccgtaatcat aagaagtaat ctgtggcaaa
     7681 tcaatcactc ctctagctga gcaaccattc ataaatccaa aatttgttcc tccatggaac
     7741 atatacaggt taatacttcc tctcagcacg acctctttga ttgcctcagc taattctttt
     7801 gcatcacgtt gtacaatcgg ttccttccaa cgattaaacc aaccatccca aaattccata
     7861 cacattaaag gccatttttt cccatgctca ttgaagaaag cttccattga agaaaaattt
     7921 tcttcagcct ttgaaccaaa atttccagta actaaaatat cttcatcaat catgctgcct
     7981 gctctgagtg tcgcacgcca tggtccatcc gaagtgaaaa atggcactgt tattcctctg
     8041 tccaacatta aatcacgtat cgaacgtaaa tagtcttttt cttctccata agaaccgtat
     8101 tcattctcaa tttgaatcat taaaatattt ccaccatttg tcagctgatg cggcacgatt
     8161 ttttttatta aaacatcata ataatctgcc acatggttca aataaacggt ttcatttgtt
     8221 cggatccgag ttccctcatt aagtaaccaa gcaggaaaac caccaaactc ccattctgca
     8281 caaatatatg gagatggtct aacaatcgcg tatagtccta attcctcagc aatggacaaa
     8341 aaatgttcta agtccaaaat tccctcaaaa tggaaatctc cttttttagg ttcatgtagg
     8401 ttccatggta cataagtttc aactgtatta aatcccaatg ctttcagatt atataacgag
     8461 tgataccaat cggctgaatc cactctaaaa tagtggatag ctcctgagag tatcttaaag
     8521 ggcttaccgt ttagaagaaa atcttcttta atctcaaatg tgttcaaaag ctccctcctt
     8581 aaataaaagc gttttcaata tattgatata ttaaataatt tgaaatagaa attcaaccat
     8641 atccaacata acagaacgtg ttaaaatcaa attatacata caaaaccaaa gactctaacg
     8701 aaaagtttaa ttctttgatg ttgtttgaag ggttaattta gacatcccaa aatggcaata
     8761 aactttatac agaagcagaa ttaatacaaa tatttaacgt aagctctatt acagtcattc
     8821 gctccctgaa tgaataaagg atggattcat aattcgtcat caaggtcgtg actcatttgt
     8881 ttcacgtaaa gaaaaactgt tctagttttc tgacattgaa ttattcacta tcagtaatga
     8941 tcaagtccaa gttttatcaa tcgttcgagg gaatgatcca cactatttaa acaagcttaa
     9001 actgccagcc ttagcatttt atgattacat cagacattta cgaaaaacta aaaaactgca
     9061 tatatctatc agcaaactta tttgcccgaa caatatgtgg atcctaattg tcaagaattg
     9121 tgttattaca attccagctg tcagcgcttt aaacaagact acaatatcca catgaatgag
     9181 gaagatttta cggaaacaaa taaaattata tttccaactc ctttaaatgt tgcgaaatca
     9241 ttaaagattc ttaccgatga aacgaccgtt ctgcaagtcc gagtgacgaa acgtagagat
     9301 tcacaacaac tactggagta cgttgaatcc tacaaaaatg gaacttctac caaattgagt
     9361 tggtctcaaa aaatcattga ttttatctag atcgattttt tcactcaatc ttttttacag
     9421 ttattttttc aatatgcgat tgaatattca ccggtgaaac atgacctgtt tgtccttctt
     9481 gtgcattagc cataccagta gccatacaaa acttcaaaag ttctatttca tccatttctt
     9541 gtgataggcc gtaggcaaat ccagcgactg tagcatctcc tgaaccaact gggttgactg
     9601 cttttatcgt agggagcgta actcgataaa aacaatcttt atgttttgcg agagctccag
     9661 cttttcctag agaaacaatg atccattcaa tacctgcgaa gataggttga atcaattctt
     9721 cctggacttc ttctaatcga tcaatcgaaa atgaatgtct cagtagtgtc gataattcct
     9781 caagatttgg tttgattaaa aatggcttct gtttgccagc taaaacctga tgcaagcttt
     9841 ccccagaggt gtcgacaaga acctttgcgg actgctcttc tgtcaattgg accaacgttt
     9901 ggtaaaaatt tgatggcaat ccttttgcaa gactacctga gattgtgaca atctttgctt
     9961 tttttattag ctccttgaag ttttctagga aattctgctg ttcttcatag gaaactgttg
    10021 gtcccgcttc caaaatctca gtttgatttc cttcatgcaa aacagcgatt gaatcccggc
    10081 tttcttcttt gatatctgta aatttctgct taataccggc atgctttaat tcatctgcaa
    10141 taaacgcccc atgataccca ccgagaactc ctgtagcgag tacatccccc tttagatcat
    10201 ggattactcg ggttacatta agtccttttc cacctgctgt tttactaact tgatctgttc
    10261 gattgacagt atccacattc aaggaagcaa gcggatagga aatatcaatt gacgggttca
    10321 tcgttacagt tactatcacg agctctcctc ctagttcaca gctgcttctt tttcaacttg
    10381 gactttgtca taccaagaac tggctgtttg tgccaaaacg ttgttcaagc tttcgatatt
    10441 ttcacgacct tcacttttca gccaggcacg agcagattct tcaccagatt tgataaacgg
    10501 cttcacacca tttttccaag tagctctacc acaaagcaca ccattaaagg tcgaacctga
    10561 atctttagca aaaaacaatg tttgttggaa tagcttcgta gaaacaccgg cactcaagaa
    10621 aataaaaggc aaatctgtcg cttgactttg ttccaagaag tactttgccg cctcctcttc
    10681 ggtatacgct acttcatctg tactgaaacc ctctacaaaa ttcatattga caggaacttc
    10741 tacctttaaa acatctactt tgtactgtgg tttcgaaaat tccttcatca tgctattgac
    10801 tttatgcggt tttactttgg catattcaag tgaatgaaca tctgaaattt gggtatcata
    10861 tgatagcaat tctaaataga atggcaaatc ttcttcggca cactcgctac ctaaacgttc
    10921 tacgaagaca tgcttctgat gattgatttc cggatcttca tctacgtcat aataaagtag
    10981 aaacttaatc gaatcggctc cttgctcttt taatcgtaaa actgaccaat ctgctaataa
    11041 atcaggcaag cgtcccggtg ttgttacatc atagccggtt ttttcatagg ccaacaacaa
    11101 accagcatct tcatgtcgtg cacttgcagc aggaagacca tattctgggt ccaataaaat
    11161 agaagatgca taaggggtta attcactaga aactaactcc ttgaaacgct caatctgttc
    11221 atcatttaat tctacattta aggctttgat catttttttt aatgctccgc gttgatcaat
    11281 cgctaaggca ctgataatac catcttttgt cgataaacga tccattgctg ctttttttcc
    11341 tctggttaat gtaatcatgg ttcttcctcc cagtttattt ttacttatat ttgtgaatcg
    11401 ttacaccttt tacaactcgg ttaactgttc ctgttggtga cggtgtatct ggtttattat
    11461 tcactttaat cgatgataac aaagcgacta tttgggcaac catgatatag cttagtgcta
    11521 aatagccatc tggcagtaat tcggcctcag ttgtaaactc gaatttatcg ccagtgaaat
    11581 tccgttgccc tggttgagta atggcgaaca ctccggaagc gatttcatct ccacgcactt
    11641 cttctaagac atccaagtcg taatcacgcg tgtaaggatt attattaaca aaaccgaaca
    11701 tgattgtttt ttgattaata aacgactttg gaccatggcg aaagcccatt gatgaatcaa
    11761 agatggtagc aatttttccg gctgtcaatt ccagaatctt caattgcgct tcccttgtta
    11821 atccagctag acttcctgaa ccaacataaa caatgcgttc aaaatcaagc tgaacgattt
    11881 tttcaatttc atttactcgg gtaattactt catttcctaa attatttaaa accttcaggt
    11941 attgttgttt cttcactaat actgtttgat cgaatgtcaa caaagctcct aaagtcatgc
    12001 aggaaaagct accagtcata gcaaagccac tatcattgga acgtgctggc atcaagaata
    12061 aaaaactatt ggaatcggat tgactaattt gagctagttt tccttctaca gcacacgtaa
    12121 ttgataaatg atagatcgta tcaaccatct gatttgcaat ttcaactgct gccaagcttt
    12181 caggactgtt tccactcctc gcaaatgata caagtaaagt tgggtcttct ttaattaaat
    12241 attcttcagg ttctgcgaca atatcagtcg ttccaatact ttcaaagcta aatgcttggc
    12301 gatcaccgtt cttgcgcaaa taaggaacta atgtgtctcc tacatattga gatgttcctg
    12361 caccagtgaa gattacacgt gttcgctgac catttgcctt ttctttaact attgcaagaa
    12421 aattatctaa ttccttttga actgtttgat agtgatcaag ggtttcttcc caaagttcag
    12481 gctgttggcg tatttcgcga gtcgtgatct cagcacccag ctgatccagt ttttcttttc
    12541 ctactgtaaa catgtttcga ttctcctaac tatttcgaat atggcggatc tgataatgaa
    12601 attgatccgc acgggcgaca cttaaagtaa attcgataat ttcatttttc atattatagg
    12661 tttgacgtgc taaatgaagg acaggtgctc cttctgagat tatcagctgt ttcgcatctt
    12721 cctttgaggc aacacttgca tatagctctt catctgccaa tcgaacggtc tgattaaaat
    12781 cctcggaaaa aagatcatat agaggtttgc ttcttaaaag ctgatcattt aatgataaga
    12841 aaaatttgac tggcaaatag gtatcttcga tcataagcgg ttcccgatca gctatccgca
    12901 atcgacttaa tttgaagact acttctccta atgaaagatt caattgtttt gcaataaatt
    12961 tgtccgcttc aattttttca aaagctaaga tccgcgtctc agcagttcta cctaaacttt
    13021 tcatttgttc agtaaagcta taggttcctg ctaaatctgc tacgttcttt ttgatatcgg
    13081 atacaaatgt tccttttcca tgtctccgat aaatataacc tgtattttcc aactctttca
    13141 aagctaatcg aaccgttgta cgactaactc cgtattgagc agttaattct cgttcagagg
    13201 gtaatttatc atggggtatc atgttacttt ccatctgatt tttaagtaaa tctaccaact
    13261 gatgatacaa agctttgttt ttaaaagaat ttcccatagg tttctccttc ttttaaactg
    13321 gttataacca caaactaatg gtaagatggt ttttttattt ttgtcaacaa acaatctgaa
    13381 aaaaattcta caaccgtctt aaatcgttga tttagcaatg attattttat tgaaataata
    13441 aaactatcca tttttaagaa attgttccta gcgaaaataa cagtcataag tgctgaaatc
    13501 tgataccagt tgaaaaaaac aggaaataga aacctactaa tcttagtatg tttatttgct
    13561 taaaaaagtt ttatcgtgac gaatcatgat tcgccgtttg aaatgataaa aatttcgttt
    13621 aaatactttg ataggcttgt ttaaacattc tagtaatccg tttgagtaat tgtagcggag
    13681 ggcatttcgg atctgtgtca gaaactttct aaatgttcgc aaagttgtcg tataggtttc
    13741 ggtttctctg gttaaatagc ccccaaatag tgaatgatgt cttttctata ccgtttaaat
    13801 cataaaaaaa tgttggcgaa tttcgccaat atcaaaaagt gtagagccta aaaaagcttc
    13861 tgctttcgta taggtagtac aactctccat ccaatctata tattcttcct atctgtattt
    13921 aatctagaaa aaaagaatca atcccttatt cgttgggatt gattctctat tcgtctcttt
    13981 atttacttct gtaggcaatt tttgttttat actctgaatc tttcagctaa cctcagctct
    14041 catcaaagag ctcccttatt cactttttct gactaactaa atttgttaca actgattctc
    14101 tgtataattc atttcgataa aactggcatt atggtaattg gcatctaatt ttctctgaca
    14161 taagtcaaaa aactggcggt tatgggtgga aaagatgatc tgtgttccta gcttaaatgc
    14221 aaggattctt aatagatcaa taaaggataa ttcattaaga ctatctaagt gttggattgg
    14281 atcatccatg aaaatcgtat tcactttgtc tgtattctct agagcggttc ctagaaaaat
    14341 acttaaagac aatatattta cttgggcaga acttagatat aaaatcgggg catcctcttc
    14401 atcctctgtt cgtttgcaca taatatccag tcctaattta tcgggatttg cttcattgat
    14461 tttaaaacta atcttacgaa aatcagggtg aggttcgatc atttgaaaaa tctgattgac
    14521 ggtatataag ttaaatgtac ttttgatttg ctttttgatc tcggttaatt tactgtcttt
    14581 taattctttt agttcttgta cttttctact taagtggtca tagatttttt ttacttttgc
    14641 ttgttcgctt cttttcgttt cgatacctgt ttcagagata aaatcactgg taagcccaga
    14701 tagttgaccc aacagttgat ttttttcatt taatttgtaa atagctgtag tcaatttttg
    14761 cttatttttt tccaattctt ctggtgcaat gattacttgg tcaaacagtt gataagatat
    14821 cttttcgata tatttcctcc gtacaacgag ctgccgaatc tgctctgctt ggattcgttg
    14881 ttcttctact aattctgttt tacttttccc atttacttgt tctagtcgtt gtttttttcg
    14941 gcaataagct tggtttcttg ttcattgatt ttttctaact cgcgtttaca ttgcctttta
    15001 aaatcagaga taacagaaat accaagcgct tcataaaacg cctgttcttg ctgataatgt
    15061 tgatactgtt cgtttccttt taaatcattt aagctttttt tcgcttgttg ataatgtaat
    15121 tcgatcgttt tgagcgtatg agtattcttg acattcagct gttcattttg attgattttt
    15181 tctttgatat tttggtactc attcgttaat tttaccaatt cctcctgtag tgactttact
    15241 cttttctggg tttcttcagc aattttttca cagtcaatcc catatttttg gctgtattca
    15301 tttaacttgt accagtgttt ctcattggtt aaatacgctt cttcttgttg ttttaatttt
    15361 aaggttactt gtaacagatc ttggtcaagt tggttgattt cagtttcctt aaccgttatt
    15421 tgtatctgaa tctgttgttt tactccagag actacctcag ttaaccgcct agttgattca
    15481 tcgatcattc cttctaagtg gctgatttcc ttcgtcagtt gctcaatcgg taaaagatct
    15541 gccgtactag cttcaatttt ttggatgata tgttgaaatt cttgatgatc atggagacat
    15601 aatggacaga cagacgaaga cgtatccgtt acgatagaat aacctaattt tttcaactgt
    15661 tctaactgac tgcccagatc ttctaaagag gaacgttcct tcttcttttg tgttaaatca
    15721 acttccaatt tttttctttc ttgccaaatg tcatcaagtt ggcttatctg ttccaacaaa
    15781 aatgaataat caggatcttt tgaatagtct ttttggctta actgatgatc gtctaagttt
    15841 agtaatgaaa acaattttgt caacgttagc tttatcttac ctaacttggc ttccaaccct
    15901 atttttttct ttttctgttg tttgatttca tgatcaagta attgtctttt cgctttaaca
    15961 tcggaataac tgtttaattc tttgatttct gttaattgat tcgtccgcaa cgctcgttta
    16021 ttttgacact cacttaatgt tacttcttgc tcttgatgct ccttttgtaa agtaatcaat
    16081 gcttgttcac atttttttcg ttgattaatc cattcattga tttctctatt actgttttgt
    16141 tcagccattt ctagtgcctg aaaatctgct tcatgattga taagaaagtt acaacgcttg
    16201 agatggttgc tcaagtctat tttttcgtca aacagtgctt tctttttttc ttcgattgtc
    16261 tcaatttctg tcaaatgggc taacttttcg ttgacatcag caacctgctt ttcagaccat
    16321 tcgatctgct gcggtatttg tcgatactct tggatcattg tgattaaatt ttctagctgt
    16381 tgtcgctcct cttcaaactg gttcaatttt atttgattat tgctttttaa tttgttcgat
    16441 tcgatataca attcttgtaa acctaattga ttctttaaca atggatcttt tttactattc
    16501 tttccgttta acttggcata attttctttc agctggttga ttgtttgcca tatttttgca
    16561 ttactttcga gtttttcaat ctcttttgtt agctgattca ttttagtttc ttgttgtcct
    16621 aatactttat tcatttcatt gacgaataag actagatttt tataatcctc agatacattt
    16681 tctttatccc aaaaattact taaagcatca tatcttcctt cggcactctg cgatcgtaaa
    16741 aaagcatcga tttgattgtg tgtcaataaa tttttttgtc gtaaaatctt taattctttc
    16801 gctgttaaat caaccgtttt tttggtctca ttcccttcaa cgtaatccgt cgtttgcttt
    16861 ccatttaacc ttttcgtcgt taatgcataa aaactgccat catcaaatgc tagttccaca
    16921 ctgtccactt cggctgagga atatttgttc tttaaaatat actttcgctc ttgggaggcg
    16981 atatcacgga catttttatt ttcattcagt cgactgattt cgccagtcaa gctccattcg
    17041 atggcatcaa aaaaagaggt ttttccggtt ccatttggcg catacaaaac aatcaaattt
    17101 gatatttcat taaaaacagg attcacacaa tcaaaatatt tttgcctttc aaatgctcga
    17161 aacgaatcaa tttttatccc tttcaattta agactcatcg gttccttcct ttacgttaag
    17221 atttgacagc tcatgtttta tatactcttg tattcgtgct tttttctctt ttttagccat
    17281 cgtttttaat tctgctaaca aatggatgat tttctcatca ttttgccgct catccttagc
    17341 cagtttcttt actggttttg tctgttccag attcaataat aatctttttt gaattttatt
    17401 tttttgtgct tctttttgtg cttctttttg tgcttctttt tgtgcttctt tttgcgcatc
    17461 attagtagca aattctcgaa aattatccac gatcaccttt ctggttgcat acttgtcttg
    17521 ttcaatactg gctttgattg gcttcgctac tttggctttg acaaaaagaa aaaaataaat
    17581 attccatcgt tcaatcttcc tttttaattg actttgaaaa ctgtaggcaa tctgatcgtt
    17641 gatttcttca tagttggcta ataactcatc ttgattatca aatacataac aaaaaaaatg
    17701 gagtcgatac ttttcgtttg cttgttggta cgtgtaacag gtcaatcccg tcgttttttc
    17761 tattatttca tacgtagtga tttcttttaa tatctctacc attgttacct acctccatta
    17821 gtttgcaatt tcttcaaaca aacgagttaa ctcctctgga aacctctgag aaaactcaac
    17881 ggctgttaac ccttttgtgt cgtgtaaaat ctgatcaatt tcattttcga tataatcgac
    17941 atgaacaata ggaaataatt ttttttcatt gggattatca atcgttaacc gatcagaaac
    18001 ttctggatga tcgatgttca cgacgattcc ctcaatttgt tctcgcttgg caatactccc
    18061 accccgaaat tttctccttt gattagttac aaacaaaaca tcttgtttat cgagcttgtc
    18121 ataaagtgta cttctaaata aactcccaat gaaacggtca agtgttagat gatttgtaaa
    18181 taatacatgg ataccagctc tttccttttc ctgagtgagt aatttgaaac aatcatcgat
    18241 ctcaaaagca atatttgttt gtaataactt gtaaagcaag atctccagcc aagcgatcca
    18301 caagaattta ttggtataat cctcattttt ctgagaagga agaaacaggt aatcacttaa
    18361 ccgattatgg atcaatttag gcgttatgtc ggaaaaacat tcacgataac atttttcaat
    18421 cagaaaaatc agcttatttt cttgtccacc tacttctcgt aattcattta tgatagatgc
    18481 caaatattca ctaaaatcat tcaagcaacg aggtaccagc atgatatcaa actcttctaa
    18541 aaagaaagca acgatatgtg cgatatgaat cccttcaaca attccttgtt gccccgctga
    18601 ctgaagtttc gtaataatcc cagtcaaata acacttccct tctctttcga cgtacactcc
    18661 tgatcctgag caacctcgta tgttctcata ctccgtgttg ttagacgatc ctatttcatt
    18721 gtccagtacc aatttaaaaa tatctggctt actgatttga gttgcctttc ctcgataagg
    18781 agttccaccg tcttctttca tacactctgg ataaccataa aatacgattt cttgcttatt
    18841 ttctggttcc attataagca gttcaggata accttttttt accttcactt tgataatcgc
    18901 taaatctaga ctatctgagc atcttggcgg ttctaagatt tctagttcag attgggtata
    18961 atcaaacagt ttgaagtcat taattgtttc cccaaccaca caatgttttg cggtgatcac
    19021 aaaacccgtt tcacaatcct gctgatacaa caaacctgaa ccataagtat tggttcctct
    19081 aatattcact gataactctt caaaatcatt catatgtcaa tcgttagtac cctctcattc
    19141 atttttttct tgatcaattg aatcccgtat ttttttattt cttcatttgt aaataacccc
    19201 tcactcgcat cggaataatt aaaataaaaa ttcgttggtc gtttttttgt gtagttgtgg
    19261 taaacaatcc ttgataaggc ttctttgtgc ggaaaaccat gacgattccc cttatttgaa
    19321 ctaatcaaat aattttcaca ctcaatctgt tttaataaat cgtcactagt attcgcttta
    19381 ctcccatgat gagccacttt taccaagtca aaatgcagct ctttttcccc atatagttct
    19441 tttaacttcg cagtgacagt acttggatga gcatctgcta acatcaacag tcgtttgcct
    19501 tcatactcca atataaagct aatactgctc ccatttgcga cagcgcgatc ttcttggaaa
    19561 gcttttttga tcagttcctc tacgcttccc tgatgattga catttcgacc gctgatcagt
    19621 tgatccctgg tttctttttg aattgccttt tcccaatctg tatataattt ccttagactt
    19681 gcttcatcag gtgtcaaaat cgtcattttt gccccattga gtaatttggg ctgacaagaa
    19741 ttgtcaataa ctgtcatctt ttcaatcctc aaattctcca aataccgatc gaaagactcc
    19801 ccttgtttaa aactaatctc tgacttttct tgaacgatct ccagttgatc atcataaaca
    19861 acctttgtat caaacttttg cgataacagc tttctagaat taaaaaacac tcgtttaata
    19921 catgacttat caaaactcga ctgagaaaac aaactcaaaa atccccgaat atgatcggca
    19981 tcaatatgtg tcaaaaccag taagtcaatg cactcgcctt tctggctaat tgttgcaatt
    20041 tcctctttca actgcctaac aacttgttgt ccttgacctc catcgacaaa cagattcgtc
    20101 cgttgatctt cttctccata ctgaacaatc aaacaatcgc catcataagc aggtaaagct
    20161 ttcactgtaa tcatttctct ttcattgcag tcctgtccct gcaatctcct ccttcttctg
    20221 ctttcttttc gctgatcttg ttattcttta ctaaccaaaa tcacacacaa taaacttcta
    20281 ttcatttgtt attggcactg gaattcagct gacaagaaga gctttcagtc cattagttaa
    20341 ttgcgcgaaa tacactcttt tctttcttat cttactcccc ataacattgt tattgtaaat
    20401 aaattttgat ttttaaacgc caagcattct cataaccaga aataattgct tgattcataa
    20461 ctcgccaaat aattgagaag gcgaccaaaa aatagcacaa gcaaaaaaag ccagcaagac
    20521 cattttaagg cttgctgact tcaattcttg attgttaaaa tttagcacta tacagacaaa
    20581 tgaagctcaa atgatcactc aattcccaaa aaatactgac tctcactggt tcttgagttc
    20641 aattaccatt gctttaattc tatctcttgt ttttctaaaa gctgatgtta tttctgcttc
    20701 ggttccaact gcttgtgcgg ggtctgttaa atcccaatga atgtgctgaa cacctacagg
    20761 aatcgtcgga catttatctt ttgcatctcc acaaagcgta ataatcaagt ctgcttgtgt
    20821 aaaataatcc tgatcgatca aatcagacgt ttggtttgaa atatcaattc catcctcagc
    20881 cataacctga accgctcgtg gattcagtcc atgagtttca atacctgcgc ttttaatttc
    20941 cacatccgag gcagataata attgacgtgc atatccttcc gccatttggc tacgacaaga
    21001 atttcccgta cataaaaaat aaattttttt catttttatt tctcctcctg gatatgagca
    21061 ttcaatatag ctcggtcatt attttattct ctaactaaaa gcaagcatac aggaattttt
    21121 gtaggaaagc atcaaaaaag agtgaaatga ttgaaaagtt acgtcatcaa ttatcagttt
    21181 ggtatgtttt ggccatcagt tctgatcttc tttttacctg ataaataata aatggcatta
    21241 tccatggatc gcctaaaatt gaagaaaatt catcatattc gatgtcatga atcatttcct
    21301 aaaagaattt ttttactaac gaatgctaaa tgaacgcttt gttttaaacg gtagtttgaa
    21361 gaaccttatt ctattgaaag aagctagaat aaccgtagct attagcaccc cacccataat
    21421 ttcactacat ttggttttat actaaaaaaa tgaaataaat tgattgattg aacacattga
    21481 aacctaaact tgttccttta aacttaaatt gtaagcgaag atcgtttaca taaattatat
    21541 taaagggagg aataccataa aaaaaaaatt accattggtc agcctattgt ttggtttcat
    21601 tgctttaatg tttttcttac cactaaccaa aacacatgct gatgtcaccg taacaaacga
    21661 ttgtacagat ccgtcacatt catttacagc ttccattaac gcagataatg gaaaagatgt
    21721 ctcgtcagac tactacaaag taacagttgg acaaacagaa tcttggcgta gaaatgatcc
    21781 tagaggccat attttagcca ttgtttattt agaacaactt aggacctact atactccaac
    21841 taacgctgcc tactctttta aagatggaaa actttattcc caaggtagca caacagaaat
    21901 cactccgtta aaagttgaaa caaattcgct tgttacgcga agcatgaacg ttaacatgat
    21961 taatctttct acaagtctta cgacagtatc gttaagtaaa tggaaaagtg gcggatcgac
    22021 agactacttt gcgctaaacc accttgatag tgaaacttgg agcagaaatg atgatccaag
    22081 aggcttttta gtttcagtcc tatataatgg cggattctca aaagaataca tatattattt
    22141 acctatataa attgagttaa attgtattcg tttttcctcc tataggcgta tactaaagaa
    22201 aacacttgag gagtggggaa catggaaaca gaacgccaaa tccgtgaatt ggaaaaagcg
    22261 atgaatacga cagacaaccg ccggttgtac gagcgtttcc tggcagtcaa gttggttctt
    22321 gaaggccaca cccggaaaga agccgggcac accatcggcc gcgacgagca tactgtcagc
    22381 cactatgtga aaaactactg ccataatgga atccaaggtt tagtctccaa aaaacaaagc
    22441 ggacgacctt cacggctgac agatgaacag gaagcggaac tggtccaaat cgtcgcctac
    22501 cacactccgg aggaagtagg tttcaaatcc cgtgccaatt ggacattggc gattgtgtgt
    22561 gacctgattc tccgggaatg gagttatgga tatacgcaaa aaggcgtggc ggacctcctt
    22621 caccggctag gactaagctg gacccgtccg acgtataccc tcaaaaaagc ggattccaag
    22681 aaacaacagg tatttttgga agaaaccttc ccgagcctaa aaaaaaattg ctgaatagcg
    22741 atattgacca cctcctattc gaggacgaaa ccatgatccg ggattaccaa gccattggct
    22801 gcacctggtt tctccgcggc caccagcgaa aaatccccac ttatggacaa cacaaagggg
    22861 taaaattgat aggcaccttg gattatgaaa ccggtcggat catttgtaca gaagaagggg
    22921 catacgacgc agcggccttc ctccgttttc tggagcggac gttgcgggaa taccccaccg
    22981 gaaaaatcgt gatggtattg gataatgccc ttatccacca cgccaagctg atccagtctt
    23041 ttcttgaaga aaacgctagg cgcctggcac t
//
LOCUS       DAIGTA010000047        22625 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.048, whole genome shotgun sequence.
ACCESSION   DAIGTA010000047 DAIGTA010000000
VERSION     DAIGTA010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.048"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..158
                     /locus_tag="NOB43_001934"
     CDS             <1..158
                     /locus_tag="NOB43_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982785.1"
                     /translation="KVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRPTNHTK
                     KWMAKNR"
     gene            378..1085
                     /locus_tag="NOB43_001935"
     CDS             378..1085
                     /locus_tag="NOB43_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0982786.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(1145..1789)
                     /locus_tag="NOB43_001936"
     CDS             complement(1145..1789)
                     /locus_tag="NOB43_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HCI0982787.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            1916..2203
                     /locus_tag="NOB43_001937"
     CDS             1916..2203
                     /locus_tag="NOB43_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982788.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            2311..2631
                     /locus_tag="NOB43_001938"
     CDS             2311..2631
                     /locus_tag="NOB43_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0982789.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            2712..4025
                     /locus_tag="NOB43_001939"
     CDS             2712..4025
                     /locus_tag="NOB43_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI0982790.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            4022..4741
                     /locus_tag="NOB43_001940"
     CDS             4022..4741
                     /locus_tag="NOB43_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HCI0982791.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            4869..5420
                     /gene="raiA"
                     /locus_tag="NOB43_001941"
     CDS             4869..5420
                     /gene="raiA"
                     /locus_tag="NOB43_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCI0982792.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            5642..8176
                     /gene="secA"
                     /locus_tag="NOB43_001942"
     CDS             5642..8176
                     /gene="secA"
                     /locus_tag="NOB43_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCI0982793.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            8303..9404
                     /gene="prfB"
                     /locus_tag="NOB43_001943"
     CDS             join(8303..8374,8376..9404)
                     /gene="prfB"
                     /locus_tag="NOB43_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCI0982794.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            9509..10195
                     /gene="ftsE"
                     /locus_tag="NOB43_001944"
     CDS             9509..10195
                     /gene="ftsE"
                     /locus_tag="NOB43_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCI0982795.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            10179..11072
                     /locus_tag="NOB43_001945"
     CDS             10179..11072
                     /locus_tag="NOB43_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982796.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            11224..12672
                     /gene="cls"
                     /locus_tag="NOB43_001946"
     CDS             11224..12672
                     /gene="cls"
                     /locus_tag="NOB43_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI0982797.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            13009..13866
                     /locus_tag="NOB43_001947"
     CDS             13009..13866
                     /locus_tag="NOB43_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCI0982798.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            13981..14901
                     /gene="pstC"
                     /locus_tag="NOB43_001948"
     CDS             13981..14901
                     /gene="pstC"
                     /locus_tag="NOB43_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HCI0982799.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            14901..15785
                     /gene="pstA"
                     /locus_tag="NOB43_001949"
     CDS             14901..15785
                     /gene="pstA"
                     /locus_tag="NOB43_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCI0982800.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            15800..16606
                     /gene="pstB"
                     /locus_tag="NOB43_001950"
     CDS             15800..16606
                     /gene="pstB"
                     /locus_tag="NOB43_001950"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI0982801.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            16622..17380
                     /locus_tag="NOB43_001951"
     CDS             16622..17380
                     /locus_tag="NOB43_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI0982802.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            17393..18070
                     /gene="phoU"
                     /locus_tag="NOB43_001952"
     CDS             17393..18070
                     /gene="phoU"
                     /locus_tag="NOB43_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCI0982803.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            18292..19326
                     /locus_tag="NOB43_001953"
     CDS             18292..19326
                     /locus_tag="NOB43_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCI0982804.1"
                     /translation="MQKKISIIITLFFICILASWFIQRQAALYDVPVIEIERVRIEED
                     QQLITGRLMNTDQKGEVISLTAPYQKNQIETANITTRQIYLVQMHGDEWQLVAKKNDG
                     WLFFFTSVFIGTMLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAILFV
                     VIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTR
                     PYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVIGS
                     MANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIAVL
                     FFLAVRRLKK"
     gene            19323..20090
                     /locus_tag="NOB43_001954"
     CDS             19323..20090
                     /locus_tag="NOB43_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCI0982805.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            20190..21758
                     /gene="liaX"
                     /locus_tag="NOB43_001955"
     CDS             20190..21758
                     /gene="liaX"
                     /locus_tag="NOB43_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HCI0982806.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENGEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            21934..22242
                     /locus_tag="NOB43_001956"
     CDS             21934..22242
                     /locus_tag="NOB43_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HCI0982807.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            22242..22592
                     /locus_tag="NOB43_001957"
     CDS             22242..22592
                     /locus_tag="NOB43_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCI0982808.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
BASE COUNT         7442 a         3928 c         4896 g         6359 t
ORIGIN      
        1 aaaaagtaga cgaagcagct gaaaagttat atgatttggt caaatcagaa aaatacaata
       61 ttgaagtgaa tattccgaaa aaaggcggaa aagcggtcca ggtaaaatca aaacgcccaa
      121 cgaatcatac aaaaaaatgg atggctaaaa accgctaata ataacaaaag atccataagt
      181 cggcattttc atcgatttta gggtcttttg ttattttcta ggttgaacat atctaaaaaa
      241 ttgtttctga caataggagt aggaagaacg atgtgtgtct aaatcctctg ttgatggata
      301 gaaaccttta tctttttcag ttgtgaatca ggtatatacc agttataata gaagaaacga
      361 aaggacgggt gtacgttatg tcgaatcaat tacctgtata tatacagatt catgaccaat
      421 taaaaaatga aatcgaacaa ggtatatgga aagtcggaga ccgtcttcct tcagaaagag
      481 aattagcagt gaaattcaat gtcagccgta tgacgttgag acaagcaatt caaaacttgg
      541 cagatgaagg aatcttagaa agaaagatcg gttcgggtac atatgttgcg cgagaaaaag
      601 tacaagaaaa aatgtctggt gcaacaagtt ttacagaaat tatggaatcg caaaatcgag
      661 taccgtctag tcggacaatc tcttatttct tgacttcgcc aagctcaagt gaaatggaaa
      721 aactaaactt gagtaaagat gacacgatct tgcgaatgga acgtattcgt ttcgcagatg
      781 atgtccctat ttgttttgaa gttgccagtg tgccacaaaa gctgatcgat ggctacagca
      841 aagcagagat tactgaatcg ttgtatcgca cgctagaaga aaaaggcggg aaaaagatcg
      901 gtccagcgaa tcaaacgatt actgctgtgt tggcttctga gaaaattgct gactatttag
      961 aggtaaaacg aggagatgca gttcttcgtt tgcgccagat ttcttatttt gaagacggta
     1021 cgccgtttga gtatgtgcgt acgcaatacg taggaaatcg ttttgagttt tatttggaaa
     1081 aataaaaaac aggtgatccc tgattcctta cttagaaata aaagagaatc agaatcacct
     1141 gtttttatat atgatcagtt accagttgct cgtgataaga aacaggaccc tcttcaaatt
     1201 ggacttgtcc gttcagcagc tcaatgatgg attctttaaa gtggtcagca cttttttcat
     1261 ctacagcaca gatgacgcta acttgatcag tatattggat ttcttttata aaaaaatgtt
     1321 ggagttcaag ataattctgt aattttccta gttgcggata cgtgatcatc acagagatct
     1381 cctgttgcaa ggtaccttct acgattccaa tgtcagacaa tgcttgagag acagcatgag
     1441 tgtatgctcg tattaatccg cctgtgccga gtttcgttcc tccaaaatat cgagtgacta
     1501 ctgcagctac attgatcagt tgattttttt tgaggacttc caacatcggt acgccagccg
     1561 ttccacttgg ttctccatca tcgctgcttc gctggatttc atttttttct ccaatgatga
     1621 aggcgctgca gttatggttc gctttccaat gttctttttt tatttcttga atgaaacttt
     1681 ttgcttggtc ctctgattct attcgtctaa gagaacagat aaagcgtgat tttttgatct
     1741 caatctcact ttgtccattt tcttttattg tacgatagcg ctcgatcatc ttgtcacctc
     1801 tttttttcat tttctttatt cagtataaat aaagttctag gttgtttcaa cactgtaacg
     1861 gttgcgcaat cgctgtagta tgcgataata aagacaaagg taggtggatc tggggatgca
     1921 ggaacgaatg aaaaagtacg atgcaattac gcattatttg aagaacaatg gcggctctca
     1981 agtaacgttg acctttaccc aatttgacga actgctgttt cccagtaacg gacttcccaa
     2041 aacagcaagg gaaagtacag attggtgggc aaatgattat aaacaccctg aaaaaggtgc
     2101 ctatggctgg ataaatgcag gctatgaagt agttgtcatc aatttggaca aagaatatgt
     2161 cgtgttcaat aaattagtga aatctagttg gctatttgat taaataaacc gcgtttagaa
     2221 aacgttgaca aatttctttc tttttatata atagagtaac agacgcgaag aaaacgtttg
     2281 cgtagtttgt tttaaaaagg agagaaaagt atggctaaaa aaacaatcat gcttgtatgt
     2341 tcggctggta tgagcacaag tttactagta acaaaaatgc aaaaagctgc tgaagcaaaa
     2401 ggaatcgact cggatatttt cgctgtgtcc gcttctgacg cagataacaa tcttgcaaat
     2461 aaagatgtag atgtactgtt attaggacct caagttcgct ttatgaaagc tgattttgaa
     2521 aaacgtctgg aaccaaaagg cattccttta gacgtcatca atatggctga ttatggtatg
     2581 atgaatggcg aaaaagtgtt agatcaagca atcacgctca taggtgaata aatagaacag
     2641 tataactatc gaacaagcga tccaaaaaat agatcgcttg ttttttcgta tattttttta
     2701 gggcgaataa tatgaatcat ttttggggta gaaggcttct gacgagagat attaaagcaa
     2761 tagactgtga ggaggtaaat ttaccaaatt atgagaagat cgcagcagtg gaacgtttgg
     2821 gcaactggat tctttgtcat cgctgtggaa tgaggacgtc cgtcattgat ggacagcttg
     2881 cagattacgg ttatttttgt acacattgtc tatatttagg gcgatgcgac actcaacaag
     2941 atttatattt gtttgatcag cctgaagcaa aacctcgaga agtcgtcttt ttttggacag
     3001 gacagcttac tgaaaaacaa acggaaatcg caaagagaat actttgccat tcagaaaaaa
     3061 gacatcatct tatttgggct gtaacaggtg cagggaaaac agagatgctt tatcctattt
     3121 tagtggaaac tttaaaagct ggaggaagag tagcgatttg tacaccgcga gtcgatgttt
     3181 gtaatgaatt gtttttacgc tatcgttatg tttttccaga agaaaaaatc acgttgctcc
     3241 atgggaatac agcaacggct tataccttta cttcttttgt tatctgtacg attcatcagc
     3301 tataccgttt ttatcggtcc tttgatttaa tagtgatcga tgagatcgat gcgtttcctt
     3361 ataacgggga tgcaggatta gctcatgctg tgcaaacagc gattaaacca gacggacgat
     3421 tcatctactt aagtgccaca cctgataaaa agttactaaa ggaaatcaag cagacgtttg
     3481 acatccacaa acttgctttg cgctttcatc ggcgtttact tcctgaaccc gtcttggttt
     3541 tcatgaataa ttggcgacaa aaatgcaaga acaagaagaa gataaaatct ttggtgcgga
     3601 tcattcatca attaattaaa gaaaaccata tccttttatt ttgtccaagt atcacgatga
     3661 tgcatcgttt gaaagccaca cttcaagagg ctcttccgag atatgagatc acagatgttt
     3721 cttcaagaga caatcagcgg gcggaaaaag tccagaaaat gcgagaagca aaatatgaca
     3781 tactgttaac cacgatgatc cttgaacgtg gagtcacatt tgaaagaata tccgttatcg
     3841 ttttaggagc ggatcatccg gtttttacta aatcttcttt ggtacaaatc gcaggaagag
     3901 ccgatcgtaa agggccttat acgaacagtc aagtatactt tttctatgaa gaaaaaactg
     3961 cagctattcg aaaagcttgt caggaaatca aagaaatgaa tgaagaaggg aagaagatgc
     4021 tgtgaggtgc agttgctgca gtaaagatat cgtccaaaat ttaacattca gcgagattat
     4081 tggtgtttcg aaatacagat tacctcagac ttgttcagtt tgtcgcgcac aatttcattt
     4141 attggaaaca agaggctgtt ctggctgtca aaaaccaatc catttcaatc tagagagtac
     4201 gaaaaagaaa gtaaagtcta ttcccgttta ctgcagtgac tgtcaagaat ggaagaagaa
     4261 atatccgacc tatgattttc agcaccgtgc cttttttgtg tacgatgaaa atatgaaggc
     4321 ctggctcaat caatacaagt ttatgggaga tatccgacta gcaggcacct ttgcatataa
     4381 atggacgcag ataaaaaaag aatacccgac atacatctat tgtccaatac ctttatctga
     4441 aaaaaggcga acagaaagag gattcaatca agtaagcgag atgttgaaag cagcaagaat
     4501 tccttttcag atgctactca aaagagagaa gcatctgctg gctcaagcaa aaaacacgcg
     4561 aaaggaaaga ttggagatgc ctcaaccttt tgaacttgca gtcacctttt ctaagataca
     4621 aaataaaaaa atattgatta ttgatgatgt ctatacaaca ggacagactc ttttccacgc
     4681 agcagattgt ttgcaggtcg cacagccgaa aatcatccga accatttctt tagcaagatg
     4741 aattagatgt ggaaatttga tagcgattta atttgcaaat aacctagagt tcgatataat
     4801 agaattaaga agagggaaag agtggtcctt ctccttcttg attgtggtag acgaaagggg
     4861 taatttttat gtttagatat aatgtacgcg gcgaaaatat cgaagtaact gaagcgattc
     4921 gcgactacgt tgagaaaaaa gtaggcaaac tagaacgcta tttcagtgac gcacccgatg
     4981 caacggcgca tgtgaactta aaagtttata cagaaaaaac agcaaaagtg gaagtaacga
     5041 tcccattacc ttatcttgta ttacgtgccg aagaaacttc tccagattta tacgcaagta
     5101 tcgatttggt tgttgacaaa ttggaacgcc aaatccgcaa attcaaaaca aaaattaatc
     5161 gtaaatcccg tgaaacgggc atgaatactg cagatgctac tgctttattc aatgaagagg
     5221 acgaaaacga aaatgattct gaattagata tcgtacgtac gaaacgcctt tcattgaaac
     5281 caatggatag tgaagaagca gtcttacaaa tgaacatgct gggacataac ttctttattt
     5341 ttgaagatgc agaaacaaat ggtacaagta tcgtttaccg ccgtaaagat ggaaaatacg
     5401 gactgattga aacagactga tcagccttac ttaaataaca acgaaaactt gcagcagcta
     5461 ctgacagctg ccgcaagttt ttttgagttt cctcctcttt tagatgaaat atgaataaat
     5521 tatgaagttc ttactttaat acgcttaaga tatttcaatt atctataact aatgataaaa
     5581 tgaaaagtaa agtctacata gtctggataa tacacagaag gaaaaggaga ttacacaacg
     5641 catggccaat ttgattcgtt cacttatcga aaacgataag aaagaactaa aacgtttaga
     5701 tagcattgca aaaaaagttg aagcatacgc tgaccaaatg gcagcattaa ctgatgaaca
     5761 attacaggca aaaactgctg aattcaaggg cagataccaa aaaggagaaa cattagatca
     5821 attacttccg gaagcttttg cagtcgtccg agaagcagca aaacgtgtat tggggttata
     5881 tccataccac gtacaattaa tgggtgggat cgtgcttcac gatgggaata tccctgaaat
     5941 gcgtactggt gaaggtaaaa ccttgactgc aacgatgccg gtgtatctga atgcgttgac
     6001 tggcgaaggg gtccacgtag ttaccgtcaa tgaatattta gcaacccgtg actcgacgga
     6061 aatgggcgag ctttataatt tcttaggatt gacagttggg ttgaatatca actcaaaatc
     6121 ttcggatgaa aaacgcgagg cttataattg cgatatcact tatagcacga ataatgaatt
     6181 aggatttgac tatttgagag acaacatggt cgtttaccgt catcaaatgg tacaacgtcc
     6241 gctgaattat gccattgtcg atgaagttga ctcgatcttg attgatgaag cgagaacgcc
     6301 gctgatcatt tcagggcaag cagaaaaatc aacagcttta tatacaagag cagacaactt
     6361 cgtgaaacgt ttgaaagaag aagaagatta taaaatcgat atacaatcaa aaacaatcag
     6421 tttaactgaa gcagggatcg aaaaagctga agaaacattc ggtttggaca acttatatga
     6481 cattgaaaat actgcattga cccatcactt ggatcaagca ttgagagcca actacatcat
     6541 gcttttagac atcgattatg ttgttcaaga tggaaaagta ttgattgttg accaatttac
     6601 gggtcggatc atggatggac gccgttattc agatggtctt catcaagcga tcgaagctaa
     6661 agaaggcgta gagatcgaag acgaaacgaa aacgatggcg acgatcactt tccagaacta
     6721 tttccgtatg tacaagaaac ttgcggggat gactggtaca gctaagacag aagaagaaga
     6781 gttcagagag atttataata ttcaagtata ccagattccg acaaaccgtc cggtcatccg
     6841 tgacgatcga ccagatttgc tttacccaac attacaaagc aagttccatg ctgtcgtaca
     6901 agatatcaaa gatcgctacc gcaaaggaca gcctgtctta gtcggaactg ttgcagttga
     6961 aacatctgag ttattatcag atatgctgaa tcaagaacgt attcctcatg aagtactgaa
     7021 tgcgaaaaat cactttaaag aagcagaaat catcatgaat gcgggtcaaa aaggtgcagt
     7081 gacgattgct accaacatgg ctggtcgggg aacagatatc aagctagggc ttggcgtaag
     7141 agaacttggt ggcctagcag ttatcgggac agaacgacat gaatctcgtc gtatcgataa
     7201 ccagcttcga ggacgtgcag gacgtcaagg agaccctggt atgtcacaat tctacttgtc
     7261 tttagaagat gatttgatga aacgattcgg ttcagaacga atcaaagctt tcttagatcg
     7321 aatgaagatc ggtgacgaag atgctgtgat ccaaagcaag atgctgacga aacaagtaga
     7381 agctgcacaa aaacgcgtag aaggaaacaa ctacgacaca cgtaagaacg tcttgcaata
     7441 cgatgacgtg atgcgtgagc aacgtgaagt aatctataaa cagcgtcaag aagtgatcat
     7501 ggaagaaaaa agcttatcta aaccactgat gaatatggtc aaacggacaa tcagtcgtgt
     7561 ggtagatgcg catacgcaat tagaaaaaga aaattggaat ttggaaagta tcgtcgattt
     7621 tgctggcagc acgcttgtcc atgaagacag tatttccctt acagatatcg aaggaaaaac
     7681 ctctcaagaa atcaaagaat atctaaacga acgagcacaa gaagtattca ataccaaagc
     7741 agctcaattg aacggaccag agcaactgct tgaatttgaa aaagtcgtga tcttacgtgt
     7801 cgtggactct aaatggacag atcatattga tgcaatggac caattacgtc agtcaatcgg
     7861 cttgcgtgcc tatggtcaaa acaatccatt agtcgaatac caaacagaag gttataagat
     7921 gttcgaagat atggtaggtg ccattgaata tgaagtcact cgtatcttca tgaaagctga
     7981 gatccgtcaa aacgtacaac gtgagcaagt ttctcaagga acagcttctc actcagaaga
     8041 tggagatgcc aaagaaaaca gtaatactag cgcgaaaaaa caaccaatcc atgtgaacaa
     8101 ggttggtaga aatgatcctt gtccttgtgg aagcgggaaa aaatataaga actgtcacgg
     8161 aaaagatgca aactaatttc tgacagcagg attggtgaga caaattcttt tttaaagaat
     8221 ttgtctcacc ttctttctgt tatttgacga ttctgttaga ctagatataa taaaaaaagt
     8281 atagtgaaag aaggaaaaaa acatggaaat atccgaaatt cgaaatctcc tgacagaaat
     8341 gcaggaaaag gtcacaagct tcaggaggtc tctttgactt agaccagctg gaagaagaca
     8401 ttgcggaagc agaagcaaaa atggctgaac ctggtttttg ggatgatagc gaagctgctc
     8461 aaaaagtgat cagtgaaaac aatgcaaata aagaaactta tgatcaattc cattctcttg
     8521 ctgaagaact ggaagaaatc gaattgatgg tggagatgtt gcaggaagaa cctgatgcag
     8581 taatgcaaga agaagcagaa gcacgtatca atgcgctaga tgaaaaaatg aatacgtatg
     8641 aattatctat gttgttagat ggtccttatg atcgaaacaa cgccatcgtc gaattgcatc
     8701 caggggctgg cggaacggag tcccaagact ggggcagcat gcttttacgc atgtatacac
     8761 gctgggcaga gcagcatggg tatcaagtag agacactaga ttatcaagca ggcgatgaag
     8821 caggaatcaa gagtgtgacc ctactgatca aaggacacaa cgcatttggc tatctgaaat
     8881 cagaaaaagg tgttcatcgc cttgtacgta tctcgccttt tgactcagca aaacgtcgtc
     8941 atacttcttt ttgttcggta gatgtgatgc cagagcttga tgaaacgatc gatatagaaa
     9001 tcaatccaga tgatttgaag atcgacacat atcgggcgag tggtgcaggt ggtcagcaca
     9061 tcaataagac agaatccgct gtacgaatca ctcacttgcc tacaggaaca gtagtagcga
     9121 gtcaggcaca acgttcacaa ttgaaaaacc gggaacaagc gatggggatg ctgaaagcta
     9181 agctttacca attagaagtg gaaaagaaag aacaagaagc agctgcactg agaggagaac
     9241 aaaaagaaat cggctgggga tcacagatcc gttcttatgt tttccatcca tattctatgg
     9301 taaaagacca tcggacaaac gtagagacag gaaatgtcca agctgttatg gacggagatc
     9361 ttgatttatt tattgacggc tatttgaaaa tgcatctgca ataagagccc tttgttaaat
     9421 tgaaataaaa ttgtaagatt ttgcaagcaa gttgaaacat tgccatgcta taatagctaa
     9481 agactgaaaa agatatggag agaacgccat gattgaaatg aaggatgtaa tgaagaagta
     9541 ctcaaacggt accactgcta tccgcaatct ctcgattgtc atcgaacaag gagagtttgt
     9601 gtatgttgtt ggtccgtctg gagctggtaa atctacattc atcaaattga tgtatcgaga
     9661 agaaaaagct tcaaaaggaa ctttgaacgt cgcaggtcat gatctaatag ccatcaaaaa
     9721 ccgcgaagtt ccttatctac gcagagaaat cggcgtggtg ttccaagact ataaattatt
     9781 accaagaaaa acagtatatg aaaatgttgc gtacgccatg caagttatcg gcagaaaacc
     9841 tcgggatatc aaaaaacgag taatggaagt gctggatctt gttggtttga aacacaaagt
     9901 ccgagtcttt cctagcgaat tatctggtgg ggaacaacaa cgtgtttcta ttgcccgagc
     9961 aatcgtaaat acacctaaag tacttatcgc ggatgaaccg acagggaatc tagatccgga
    10021 aaactcatgg gaaatcatga aactattaga tcggatcaat gcacaaggaa caactgtcgt
    10081 gatggctaca cataacagta cgatcgtaaa tacgattcga caccgagtaa ttgctatcga
    10141 aaacggccgc attattcgag accaagcgga aggggaatat ggatacgatg attagaacct
    10201 ttttccgcca tttattagaa agtatcaaga gtttgaaacg taacggctgg atgacagtag
    10261 cttcggtcag tgcggtaacg atcacgttga ctttagttgg tgtgttcatg gcggtcatca
    10321 tgaacgcaac caaactagca caagatatag aaggaaacgt ggatgtatct gtgttcgtag
    10381 acattggtac aaaagacgaa gagatgaaaa aattagaaaa agaattaaat gacttagatc
    10441 atgtcaaaaa agtcgaattt tcaagcaaag aacaggaatt gaagaaaatc caaaacgaaa
    10501 tgggcgattc ttggaaattg tttgaagggg ataataaccc gttatatgat gtatacgtag
    10561 taagtgctac cgatccttct tatacaaaac aagtagcaga aaaagcggca gatttgaaga
    10621 atgtttcccg ttctgattac ggtggggctt cctcagatcg gattttccaa attgctggtg
    10681 cagttcgaac atggggatta gttgcggcgg cattgctgct gtttgtagca atgtttctca
    10741 tttctaacac gattcggatc acgattttat ctagacagcg tgaaattcaa atcatgcgtt
    10801 tagtaggggc aaaaaatgga tatatccgct ggccattttt ccttgaaggt ggttggatcg
    10861 gcttaatcgg tgccattctt ccgatactga tcattacatt tggttacgca tggttttacc
    10921 aattgatcaa tccgtcatta ttacgatctc attattcatt gatccatcca gaaaatatcg
    10981 tttggaaaat caatcttttg atggtcggta ttggtgtgat cattggttca ctcggctcga
    11041 tcatctctat gagacgtttc ttgaaattct agtgtcacaa gataaatata atcagaaagt
    11101 tggacgattt cgttccagct ttcttttttt atcagctagg tggagtaaat ggggcggctt
    11161 ttttctcttt actttaaaaa acaacttggg tattcttaag ttggtagaaa aagaggtgaa
    11221 gccgtgaaga ttatcgttga caattttttt acgatccttt tgattatgaa tattttgctt
    11281 tcctttatta tcgtttttcg agaaagaaag gaaactgcgc aaacatgggc atggctgctc
    11341 gttttgatgt tcattccagt tgtaggattt attttatata tttttttagg aagagggatt
    11401 tccaaagaga aaatctttga tttgaagatc caagggaaaa tcggtaagaa tctagaaatc
    11461 gaagaagata aacaagcatt gatgcgaggg ctttatcctc atccgcctac tggacaagta
    11521 gatgtgaaac aattgatcta tatgcttact gtatttgaaa gtacgcttta tacgactaaa
    11581 aatgaaatca ctttatttac agatggtcgt gaaaaattcg atgcgctgat cgaggatatc
    11641 aaacaggcag aagaccatat ccatttccaa tattatattt accgcagtga tacattaggt
    11701 gaagaagttc gagaggcatt gacagaggca gcaagacgcg gagtaaaagt cagagtcctt
    11761 cttgatgcat ggggttccac acaagtttct tctagttttt ttcagaattt gaaaaaagca
    11821 ggtggagaag tcgcattttt ctttcctcta ttcgttccgt atatcaatcc tcgaatcaat
    11881 tatcgcaatc atcgtaaaat cgtagtgatt gatgggaaaa tcggatatac aggtgggttc
    11941 aatgttggaa acgaatatct aggattggta aagaaatttg gttattggcg agacaatcat
    12001 ctgcgtatct atggagaagc ggtttacacc ttgcaaaacc gttttttgat ggactggaat
    12061 tctcagcata caaaagaagt aggatattca ccggaatttt tcccgaccat tcattctaca
    12121 ggtgatatgg ctgttcaaat cgtgacaagc ggaccagata ccgaacatga gcaaatcaaa
    12181 atgacatatt tgaaaatgat ttcgttagcc aaacgggaga tattgatcca aacgccgtat
    12241 tacataccgg atggatcgat tcatgaggca ttgaagttgg ctcttctctc aggcgtaaaa
    12301 gtccatatcc aaatacctaa caaaccagat catcttctcg tttactgggc aacgtattct
    12361 ttcgctgcag agctgatcga gtatggggca agaatcgaaa catatgaaaa tggatttatc
    12421 catgcaaaga cgatgattat cgatggcggc atcgtttccg ttggttcagc taatatcgac
    12481 gttcgctcat ttagattgga ttttgaagtc aatacactga tctatgatga acgaatggct
    12541 tctcgcgtaa gaaaagcatt ctttgaagat tcaaagattt cgacgcatct cacaaaagaa
    12601 gtgtatgaaa accgagggat gatgatcaag atgaaagaag gattagcaag actgatttcg
    12661 ccgctccttt aaaatacaaa aaggacagga gagccatcaa tagatggaaa tctcgcgtcc
    12721 ttttttctcg gggccatttc tgagagtacg tcagaaatgg agaaagcgtc tcgcatgagc
    12781 gaaattaact ttggggtatc tcttgttttt tggggaaagc aagaaataag ctaatatatg
    12841 ctattaaaag agacacattt caaagccagt atagcataga aacttttaat gagatagctt
    12901 tttttgcaat tatgagaatt tattttgtta tttaatgatt ttgattcgtt ttcatcaagt
    12961 aatgaaaatg atagaataaa catactttag gattaaagga gatttctaat gaaaaaacta
    13021 aaattattct taccaataat aggattagct attcttttat caggctgttc aaagtggatt
    13081 gatcgaggag aatccattac tgcagttggc tcttctgcct tacagccttt agtagaaacg
    13141 gttgctgaaa cctaccaggc agaaaatcct ggaaaattca tcaatgtaca agggggcgga
    13201 agcggaactg ggttgtctca agtacagtca ggagcagtcg atatcggaaa ttctgatttg
    13261 ttcgcggaag aaaaatcagg gattgatgct tcggcattag tcgatcatcg agtagcagtt
    13321 gttggaatca ctcctattgt gaacaaggat attggcgtaa aagatatcag tatggaaaac
    13381 ctgaaaaaat tatttacggg cgagatcaaa aactggagtg aagtcggtgg gaaagatcag
    13441 ccagtagtta tattgaaccg tgcatcagga agcgggaccc gtagtacgtt tgaaaaatgg
    13501 gtattggacg gagaaacagc tgttcaggca caagaacaag attcaagcgg aatggtgcgc
    13561 caaatcgttg cggacacacc cggagcaatc agctatgttg ctttttctta cgtttccgat
    13621 gatgtggata cgttgaacgt taacggtgtg gaaccaacag atgaaaatgt gacaacgaac
    13681 aaatggacga tttgggcata tgagcatatg tacacaagag accatccaaa aaaactgaca
    13741 aaagaatttt tagactatat cttatctgat gaagtacaag ataatattgt cggagagcta
    13801 ggctatatcc ctgtttcaca tatgaaagtt gaacgtgatt ggcaaggaaa cattgttaaa
    13861 gagtaatctt tacacaaaat ttacaaactt agctaaactt ttacatgtta ttaaaaccaa
    13921 attgatgttc aatttgtaca ctgagtgagt atgttaaacc tgattaaggg ggagtcatct
    13981 gtggaagatg tgaaaaaagt attattaaca aaatcaaaac gttcaaaaat ggaacagcgc
    14041 ggaaaattca ttagtttttt gtgtatcgcg ctgatcgtgt tggttgtatt atctattttt
    14101 tattttgtcg ctagtaaagg attggccacc ttttttactg ataagatcaa tgtatttgat
    14161 tttctgtttg gtacagattg gaatccaagc caaataggag caaatgggaa acccatggta
    14221 ggggcattgc ctatgatcac aggttcattt attgtgacct ttttatctgc tattgttgcc
    14281 acaccatttg ctattggagc agcagtgttc atgacggaga tttctcctaa aaacggaacg
    14341 aagatcttgc aaccggtcat cgagctactt gtaggtattc cgtctgtcgt ttacggattt
    14401 atcggtttat ctgttatcgt gccttttgtc agaagtatct ttggcgggac agggttcggt
    14461 atcttagctg gtacatttgt gttattcgtt atgatcttac cgactgtcac aacgatgact
    14521 gtggatgcat taaaggcagt gccgcgacac tatcgggaag cttcattagc gctaggtgcc
    14581 acaagatggc aaacaatcta caaagtggtg ctgcgagcag cagtgcccgg aattttaaca
    14641 gcagtcgttt ttggtatggc tcgtgcgttt ggcgaagcct tagctatcca aatggttatt
    14701 ggtaatgcgg cattaatgcc aacaggactt actactcctg cttctacatt gacgtccatc
    14761 ttgacaatgg gaatcggaaa tacaatcatg ggaacagttg aaaataatgt gttatggtca
    14821 ttagcgctga tcttgctatt gatgtcatta ttctttaata tcgtgatccg tatgattggg
    14881 aagaaaggag agctgaaata atgaacgcaa aacgctcaga taaaattgct acaggtgttc
    14941 tatatgtggt ttcagggatc atcgtattga tcttagcagc tttattactt tatatcttag
    15001 ttcgaggaat accgcacatt tcatggtcat tcttgactga accttccaaa gcctaccaag
    15061 aaggcggtgg gatcgggatt caattattta actcgattta tttgcttttg attaccatga
    15121 tcatcagttt tcctatctct ttaggtgcgg gtatctacct ttcggaatat gccggaaaaa
    15181 actggctgac agacgtgatc cgtacgtcta tcgaaatctt gagctctttg ccttctgttg
    15241 ttgtcggttt attcggtttc ttggttttcg ttattcaatt ccagtatggt ttctcaatca
    15301 tttctggtgc attagctttg accgtattca acttgcctct tttgactcga acggtcgagg
    15361 aatctttaca agcggtccat tacacacaac gagaagctgg attggcgtta ggtttgtcac
    15421 gctgggaaac agtgataaaa gtggttgttc cagaagcgac accaggaatt ttgactggtg
    15481 tgatcctaag ttcaggaaga atttttggtg aagctgccgc attgatttat acagctggtc
    15541 aaagcgcgcc agcattagat tttacgaact ggaatccatt aagtgtttct agtccgatca
    15601 gcattttccg ccaagctgaa acactggctg tccatatttg gaaaatcaac acagaaggta
    15661 cgatgcctga tggtgtttct gtttcggctg gcgcttctgc cgtgttgatc attgctgttt
    15721 tactgttcaa cttcggcgct cgtgcgattg gcaaacgatt ataccgaaaa atgacttcag
    15781 cctaaggaga agaagtaaaa tgaaaaaata taattggaat gaaacaaatg tcattaccat
    15841 gccaaaagat aaggaagttg cattatatac gaatgatctg catgtttggt atggcgacaa
    15901 tgaagcaatc aagggagtgg atctagaatt cgaaaaaaat aagatcactg cattgattgg
    15961 tccctctggc tgcggaaaat ccacgtatct tcgttctttg aatcgtatga atgatgggat
    16021 tgctaatacg aaaattactg gaaagattat gtataaagac gtggatatca atgcgcctca
    16081 agtggatgtt tatgaaatgc gtaaacggat cggcatggtg ttccaacgcc ccaacccttt
    16141 tagcaaatcg atttatgaca atataacttt tgctttgaaa cagcatggtg aaaaaaacaa
    16201 aaagaaatta gatgaaatcg ttgaaacaag cttgaaacaa gcagctttgt gggatcaagt
    16261 aaaagatagc ttggataaaa gtgccttggc tttatctggc ggacaacagc aacgtttgtg
    16321 tatcgctcgt gcaatcgcga tgaaacccga tatcttgctg ttagacgagc cggcaagtgc
    16381 cttggatcct atttcgacag gaacggttga agaaacactt gtaaacttga aagaagacta
    16441 cacgatcatt atcgtgacgc ataatatgca acaagcagct cgtatcagcg actatactgc
    16501 ctttttctat ctaggaaaag taatggaata tgacaaaaca aacaagatat ttaccagacc
    16561 aaaaattcag gcaaccgaag attatgtgtc cggtcatttt ggttaagacg gaggcctcaa
    16621 catgacaaaa gaaattatct catccaaaga tcttcatctg tattatggaa agaaagaagc
    16681 actaaaggga attgatctaa gtttcaatca aggtgaaatc acagcgatga tcggtccttc
    16741 tggttgcggg aaatctacct atctacgttc gttgaatcga atgaacgatc tgattccaaa
    16801 tgtaacgatc accggaagtg ttttatataa agacaaagac atctatggtc cgaaaacaga
    16861 tgttgttgaa ctaagaaaag aaatcggcat ggtgttccaa cagccaaatc catttccttt
    16921 ttctatttat gaaaatgtca tctatggatt gaagttaaaa ggtgaaaaag ataaaaaagt
    16981 ccttgatcaa gtagtggaag aaagtctgaa ggcagcgtcc gtttgggagg atgtgaaaga
    17041 taaactgcat aaaagtgcct tgtctttatc cggtgggcag cagcagcgtg tatgtatcgc
    17101 acgtgttttg gcagtgaatc ccgaaatcat cttattggac gaaccaacaa gtgcacttga
    17161 ccctgtttct actgggaaaa tcgaaagtat gctgttagaa ttaagagagc ggtatacgat
    17221 gatcatcgtg acccataata tgtctcaagc ttcacgtatt tcagataaga cggcattctt
    17281 tttagatggt cacttgatcg aatacaacga tacgaagaag atattcatga atccagaaaa
    17341 acaagagaca gaagattata tttcaggtcg atttggataa ggaggaaacg gaatgctacg
    17401 tacacaattt gaagaagaat tgctgaatct ccataatcag ttctacgaaa tggggatgat
    17461 ggtgagcagc gctgtgcaca agtcagttcg tgcatacatc aaacacgata aaatcttagc
    17521 tcaagaagtt atcgaaaacg atataaatat caataatatg gaaacgcgtt tggagaagaa
    17581 aagttttgaa atgattgcat tacaacagcc agttacaact gacttgcgta tgattatcac
    17641 ggtcatgaaa gctagctctg atttagaacg tatggccgat catgcggtgt ccgttgctaa
    17701 atccacaatc cgcgtaaaag gacagacgag aataccggaa atcgaaaaag agatctccga
    17761 tatgtccgat tacgtgaaaa aaatggtgga caacgtccta gttgcgtatg tcaaaacaga
    17821 cgaaaaagat gcgcgtacaa tcgccaatat ggatcaaaga gtcaatgact atttcaatcg
    17881 aatctataat gcaaccatca aaaacatgca agaaaatcct gaaacagtca tcagtggcac
    17941 agactatttg aatgttgcca gctatctaga acgaatcgga gactatgtga caaacatctg
    18001 tgaatggatc gtctacttgg ctacagggaa aatcactgaa ttaaatacga accacaatga
    18061 gattttctaa actgaagttg tgattctgct gtttatttag gaaaagaggt tgtgaaatca
    18121 gcgttttgtc ctgagtatta gagaaacaaa cggtaaaata gttcctcata ttttgccgtt
    18181 ttttgagcta ataccgaagg tcagctgatt gaacaccgtt tattctggaa aagggtttgt
    18241 gacaaaacat gtcacaaacc cttttcatta ttccaataga aaggataaag aatgcaaaaa
    18301 aagattagca tcatcatcac tctatttttt atttgtatac ttgcttcatg gtttattcag
    18361 cgtcaagctg ctctatatga cgtacctgtc atcgagatcg aaagagtgag aatagaagag
    18421 gatcaacaat tgattacagg aagattgatg aatacggacc aaaaaggaga agtgatttct
    18481 ttaacggctc cttatcaaaa aaatcaaatc gaaacagcaa atataacaac aagacaaatc
    18541 tatcttgtcc aaatgcatgg agatgaatgg caactagtag caaaaaaaaa tgatggctgg
    18601 ctttttttct ttacaagtgt cttcattggc accatgttgc ttattggtgg aaaacagggc
    18661 gtatttgctt taggaagtct catcatcaac atcgttttac ttttactttt gttgctcctc
    18721 tttaccaaaa cagaaggtat ttctctctta aatatagcaa tcttatttgt cgttataggg
    18781 ataatcgtta gtatattggc gttagacgga tggaatagaa gcagtataat caaaatttcg
    18841 gctgcagtta caagtgtttt tttagcattt tttatttgtc ttttgacaat gaatcattgg
    18901 aaagatcaag gactgcgcta tgaagaactg aattatctga cacgaccgta tcgttctgtt
    18961 tttctttcca gcgtgctgat tgggacagct ggagggacac tcgataccgt gatcacagtc
    19021 attgcgacat tagaagaatt gaccaagcaa caaccgaaaa tatcagcgaa acagttatgg
    19081 ctttcaggaa ggcaagtggg ccgagatgtg attggttcga tggctaatat ccttttattc
    19141 gtctatatca gcggagcgat tccatcgctt ctgttatatt taggaaatca atggtctttc
    19201 aaagaaacgg tagaacgaca tttatcatta gaacttttac gcgtcattgc tggcagctta
    19261 ggaatagtat tatcaatccc catcgcggtc ctcttttttc tcgctgtaag gaggttaaaa
    19321 aaatgaatgt acttattata cttgttggga tttttgcaat cagtgtgcta tttgtcggtg
    19381 gtacgcaagg tatgtatatt cttttaggat tattcattaa tttaggaatc tttttcctat
    19441 tattattcgg ctatcatcag aagtggccga tattggtatt gtcgattata gggttcctat
    19501 tgatcgctgt ggttatctta ttttttatca atggttataa tctgaaaatg cgagccgctt
    19561 ttgccagtat actgatcttt ttgttttgtt tcctactatt gattcctatc actgattttt
    19621 tagcgatcca aggctttact tcgatagaac tagaagaact atctggctta gataagacgt
    19681 tagcaattga ttttagacta cttacgaggt cgttgcttct gatcagtctt agcggagctg
    19741 ttttagatgc gagtgtagcg atttctagtg gaacattcga agtatatcag gcaaatccgc
    19801 aaatgtcttt taaccaattg cgccatgcta gctttgccat tgctaaaaaa atattggcat
    19861 caacagtgat gacgcttctt tttgcgttta tggggagttc tttagcgttg attctttggt
    19921 ttattgactt agacatttct tttcagcaaa taatcaatga aaaatcattt gtcttggaat
    19981 atacgatggc tattcttacc acactggccg cactacttgt cctgccctta acttgcgtga
    20041 ctacagcata tctctttaca aaaaagaaag aacatctcaa gatggagtaa aagttacaac
    20101 ttaagtccta tgacattttt actgaatcag tgcataatat ggatgtaagg aaaagcttgc
    20161 aaacaatttt gcttaaggag gcaatttcca tgaaagaaag agaacgtatt ttagacttag
    20221 tgaaaaaagg aatcctttcg actgaagaag gcttagattt attagaaagc atggcaactg
    20281 aaaaagacga aaaacaaatc aaaaaagaag cagacaaggt aactgctagt cataaagaaa
    20341 aagatcaggc aagtcaattg atcgatgaac ttgaaaacgg tgaagaaaaa atttctgagc
    20401 cagttgatcc aaaagaaaaa gaaagacaag atcaagaaaa cttagaaaag atcttagatg
    20461 aactagcaac tgaagcgaat aaaacttcgg cgcgtctaga cgaagtaaat gctcaattcg
    20521 ctgacaataa ggcagcacgt aatgagaaac aggaagcatt gatgcagctg aatacaaaag
    20581 aagaattagg cgagttgaca gaagaagaat tagcacagcg tcaaacgtta gaagcagaaa
    20641 tcaaagagtt agaagcaacc ggcgatacac tattagaaga acaattgaag ctggaagcag
    20701 aattaaaaga tatccgcaag aatcaatggt ctgagaaaaa agaaacattt acggataagt
    20761 ttgaattgcc agatgattgg aaagatcaag cgacagatac gctgaatcaa gtaggcgaaa
    20821 aaatgtcaga agctggatca cagttaggca aattcttgaa gaaaacattc caaactgttt
    20881 cagaaacagt aaatgataac atggaatgga aagatgtcag cttacgcgtc cctggaattg
    20941 cgacaacgaa atttgaacac gaattttatt atgaagctcc tgcagcaagt atccttgata
    21001 tcaaggcagc aaacggaaac gtgacgttaa aaacgtggga cagtgatgat gtgaaagtgg
    21061 aagccaagat caaactttac ggaaaaatgg gtgctgaacc atttgaagca ttctctgaac
    21121 ggagccagat cgaggtcaat gaagatcata tctccttcca aattccaaat aagcgtgtgc
    21181 gtgcagacct tgttttctac ttgcctaaac gagtatacga ccatgcagct atcaaacttc
    21241 taaatggcaa catcatgatt gagacattgg aagctaaaga tatttataca aaatctacga
    21301 atgggaacat catcgtgaac caattaactg caacgatgct ggaagtagaa ggtgtaaacg
    21361 gcaatatcga tattcgaaac gggaacatct tagattctat tatagaaaca gtaaacggta
    21421 cagtgacatt tggtgccaca ccagaaaacc tttctgtgtc tttagtaaat ggtgatgtac
    21481 gtcttacgat taaagaagat aatttgaaaa aagtagaagc aagttcagtg aacgggaatg
    21541 tcaaagttgc tttaccagat agcatcggtt tggaaggaca cgctaaaaca agtcttggaa
    21601 gcattaacag ccgtctgtcc aattacgaag tagttcgtga gaaaaaagaa cggacaaacc
    21661 aaatgttgca attccgtcgt gtttcagatg atgagatcgc acaagtgcag ctttcaacga
    21721 caacaggaag tatctattta aaagatacag ataaataaag aggttgtgaa agagatgttc
    21781 agccttgagc aataagaagc gattttttaa aatagcttcc cctattttaa aaaaatgtgc
    21841 cttattgccg ataggctatc tcttgaacac cgattaagaa gaaggttgtc acaacgattt
    21901 tcttcattta aaatagtaga acagaggtga gacatgatga aaaaaaagtt gacaaaatcc
    21961 aataaaaatg ttgttttgac aggtacttta gcagggattg gggaatatat cgggattgat
    22021 cccactgtta tccgtgtgct ttatgtattc ttaagcttag ttgcttttgg aagtccaatc
    22081 attttataca ttttattagc tttgattatc ccatctgcgc gttctgcacg aacaaactat
    22141 ggacataaca atgcatatta tgaaaaaaac aattatcgtg aacaaacaaa aaaacgcaaa
    22201 gaagcggaaa aaatcgatga tgacgaatgg agtgactttt aatgtcgtac tttcagcgta
    22261 ttttggttaa tacgttaaca ttcatatcgt tggctgttct ttttcctgcg atggtccatg
    22321 tgagcagtat ttggacggcc gtccttgcca gcttcgtatt atctgtgttg aacatgtttg
    22381 tcaaaccgat tttgacgatc ctgtccctgc cctttacatt agtcacattg ggattgttta
    22441 cgtttgttat caatgcagcg attcttaaaa tgacttcctt ttttgtagga gcagaacatt
    22501 ttagtttttc ttcatttggt gcagcgttat tcgtagctat cttgatgtca cttgtcaatg
    22561 taattgttag tgaacataac agcagaaaat aaaaaaagct gtgccgagat ctcggcgcag
    22621 ctttt
//
LOCUS       DAIGTA010000048        21956 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.049, whole genome shotgun sequence.
ACCESSION   DAIGTA010000048 DAIGTA010000000
VERSION     DAIGTA010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.049"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..260
                     /locus_tag="NOB43_001958"
     CDS             <1..260
                     /locus_tag="NOB43_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0982809.1"
                     /translation="AAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNP
                     GNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            505..1530
                     /locus_tag="NOB43_001959"
     CDS             505..1530
                     /locus_tag="NOB43_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0982810.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLRIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            1824..2933
                     /locus_tag="NOB43_001960"
     CDS             1824..2933
                     /locus_tag="NOB43_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI0982811.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASANTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            3016..3912
                     /locus_tag="NOB43_001961"
                     /pseudo
     CDS             3016..3912
                     /locus_tag="NOB43_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            3928..4752
                     /locus_tag="NOB43_001962"
     CDS             3928..4752
                     /locus_tag="NOB43_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0982812.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINIFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGGKL"
     gene            4784..6094
                     /locus_tag="NOB43_001963"
     CDS             4784..6094
                     /locus_tag="NOB43_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HCI0982813.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSRAYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            6242..7501
                     /locus_tag="NOB43_001964"
     CDS             6242..7501
                     /locus_tag="NOB43_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0982814.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            7511..8383
                     /locus_tag="NOB43_001965"
     CDS             7511..8383
                     /locus_tag="NOB43_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0982815.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            8395..9225
                     /locus_tag="NOB43_001966"
     CDS             8395..9225
                     /locus_tag="NOB43_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0982816.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            9265..11448
                     /locus_tag="NOB43_001967"
     CDS             9265..11448
                     /locus_tag="NOB43_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI0982817.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLQERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            11509..12729
                     /locus_tag="NOB43_001968"
     CDS             11509..12729
                     /locus_tag="NOB43_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HCI0982818.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKYSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVCLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            12726..14186
                     /gene="gtfA"
                     /locus_tag="NOB43_001969"
     CDS             12726..14186
                     /gene="gtfA"
                     /locus_tag="NOB43_001969"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HCI0982819.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVTQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            14263..15369
                     /locus_tag="NOB43_001970"
                     /pseudo
     CDS             14263..15369
                     /locus_tag="NOB43_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            15691..15900
                     /locus_tag="NOB43_001971"
     CDS             15691..15900
                     /locus_tag="NOB43_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI0982820.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            15893..16042
                     /locus_tag="NOB43_001972"
     CDS             15893..16042
                     /locus_tag="NOB43_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HCI0982821.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            16196..16330
                     /locus_tag="NOB43_001973"
     CDS             16196..16330
                     /locus_tag="NOB43_001973"
                     /inference="COORDINATES: protein motif:HMM:NF026010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982822.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     "
     gene            16490..16861
                     /locus_tag="NOB43_001974"
     CDS             16490..16861
                     /locus_tag="NOB43_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0982823.1"
                     /translation="MTVMRLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPE
                     TASSIRTIELDDNTITFLKAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIV
                     GVHIIRIHGLRHSHASLLISQ"
     gene            complement(17145..18230)
                     /gene="xerS"
                     /locus_tag="NOB43_001975"
     CDS             complement(17145..18230)
                     /gene="xerS"
                     /locus_tag="NOB43_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HCI0982824.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            18564..18797
                     /locus_tag="NOB43_001976"
     CDS             18564..18797
                     /locus_tag="NOB43_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HCI0982825.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            18794..19201
                     /locus_tag="NOB43_001977"
     CDS             18794..19201
                     /locus_tag="NOB43_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI0982826.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(20338..20856)
                     /locus_tag="NOB43_001978"
     CDS             complement(20338..20856)
                     /locus_tag="NOB43_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HCI0982827.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         7469 a         3359 c         4118 g         7010 t
ORIGIN      
        1 tagcggctaa attagtaaaa tttttaaaaa ataagaataa acgagtgatg gaacaattat
       61 cgattattgg atttgatgat attacttttg cagaattaat ggatcctgcg ttgacaacaa
      121 tacgactaaa tccaggtaac aagggggcga ttgcttttca ccaactgatt ggactggcca
      181 aacaagaaga aataaaaaat caagtactac tattagaggg agaattgatt tctcgagact
      241 ctgttcacaa aatcaaataa aaaagctctg tgaaataagt atagttaaca ataaaatatc
      301 cgaacgatag agagaatgaa ctgtgatcta gcagttcctc gtcggaaatt cactagaatt
      361 agcattattt actctaaatt gttcggatat tttttcttgt ttttaattat gattacagtg
      421 cctattttta acgaaatttg cttattttca aaatgtatga ttatatttta gtaaacactt
      481 tcaaatatga aaagaggagc tattatggta ggaattaggg atgttgcaaa acgggcgggt
      541 gtgtccattg caacagtatc gcgcgtgcta aatgaggatc cgacactttc agtaaccgat
      601 gaaaccaaac gaaagattgc agaatcggtt aatttttatc attatgtcaa aaaaagtccc
      661 gttgcaaaaa atttaacaaa tattgcatta ataacgacag tttctgaagt agatgagttg
      721 gaagatccct attttcgaac gattcgcaga gggattcaag tcgaagcaga acaaagcaaa
      781 gtcaatttga agaaaattat tcgtttgtca gaaacaccgt tggagcaaga tgatttgcta
      841 aaatgtcaag gtgtgttgat tattgggcag gtgctatctt ctgtgattga agaagtatca
      901 gcaattaatt cgaatgtcgt agtgattgat gaccctagta ttgaagctga agtagatgca
      961 gtttatactg atttaacaaa agcaacgaat cagcatttag atcgattgta taaaaaagga
     1021 caccgaaaca ttgcgtttat cggaggagga cgtgttcgtt tagatagcca aggaaataaa
     1081 cacgtgtcag atgatgatta tcgaaaaata gcctatgaga cgtggatgaa acaaaaagga
     1141 ttagaaaaat atagtcaaat ttatttagaa ggctggacca cacttgacgg aatgcaggca
     1201 gcagatttac ttttgaaaaa acatgctaaa gataagttgc cgactgctat catggtagga
     1261 aatgatccta ttgctgtggg ggtttatcgt tcacttcaaa aaaatggtct acgtattcca
     1321 gaagatattt cgattgtgag ttttgataat attgaagttg ctgaattttt aacacctgca
     1381 ttaaatacgg tgaatgtgaa tacagaagaa attggaaaac tagcagttcg catggttaat
     1441 gaacgaataa aagaagttag aaatgtttcg atcaaagtga ttgtttctaa taatattatt
     1501 gttagagaaa gtgaaaaaaa tatcgattaa aaaagtaaac atccaaaaaa ggatgtttac
     1561 ttttttgttt actaatattt ttagtaaaaa atctcgacaa aacattaagt aaacagttat
     1621 ggtgttgtta acaaaaagaa aacgcattca aaacaggagg aattaagatg aaacatttca
     1681 aaaaaatagc tttaacaggg atagctgttt taactgggac attactcgca gcatgtggtg
     1741 ggggagatag taattctaaa gacgggcaag taactttaag ctatgcgagt tgagatactg
     1801 accaagctcc aggactaaga aaaatattag atgaatttga aaaacaaaat cctgatatca
     1861 aagtagaaat ggagacaacg ccttgggatc aatattgggt taaattagaa gctgcaacaa
     1921 cgggaggtaa tatgccagat gtagtaacca tgcactctag cgaatcctat aaatatatgt
     1981 cacagaatgc tttgatggga cttgatgatg ttatcaaaga aaatgatatt gacatgggaa
     2041 actttactga aggaattgct gatttctata cgcttgaaga cgaactatac gcaatcccta
     2101 aagatgcttc tgtagtgggg ctatggtaca acaaagaatt atttgataat gcaggtgtcg
     2161 attatccaga tgaaacatgg acatgggaaa cactcagaca agctgcaatt gatttaacag
     2221 atgaatcaaa aggcatctat ggttttgcat cacatattgg aacagagact ggctactggc
     2281 catttattta tcaaaatggg ggagaagtat ttgccgatga caatacaaaa tcaggtttga
     2341 ataccccaga agcacaagaa gctttagctt tttatcgaga tattgcactt gttgatcatg
     2401 cttcaccaac aattacagaa ttacaagatc ctgataagtt aagtcgtttt caatcaggta
     2461 gattagcaat gatgattgaa ggaaactggt ttgcaccggg atttttgaaa aatgactatc
     2521 tagttgaaaa tgttgcttct gccgtgttac ctaagggaaa agttaatgca acaattacaa
     2581 atggacttgg ttgggctgcc agtgcgaata caaaataccc agaagaagtg aaaaaactaa
     2641 tggcattttt agctagtgag gacgccaata aaatccaagc ggaaacgggg gcatcaatcc
     2701 cagcactaaa aggctttgaa gacgagtggg ctgcttcttc agatacaatt gatttgagtg
     2761 cttttggaaa aatgttggag tatggagtcc ctcgtccata caataaagat ggattacgag
     2821 ctgaacaagc agaagttcaa attattaacc gtattctgtc tggtgaagta actgttgaag
     2881 atggaaccgc tcaaattgaa aaagaagtca atgcgatatt gagcggaaat taaattagtt
     2941 aattatacaa tatacaggcg aaaggattct atttcgtctg tatattaatg gatgaatacc
     3001 aaaaaggggg atattatgaa aaatcgaatt tttggaaaat atcgtaaaga tcaagtgata
     3061 tggggctata tttttatttt tccaacggca ttaggattaa ttttattaaa tatatggcca
     3121 gcaattcaaa cagcaatttt aagttttcaa aaaacggtag ggttcggtga tactgaatgg
     3181 gtcggattaa gaaattacca aaaaatgttt gcagacggtg aagtttttca gtctttatta
     3241 aacacattaa tttatgcagt ggtttcgata cctagtattg ttgtattatc cttgttggtg
     3301 gcagttttaa tgaatagaaa agttaaagga ttgtcgattt atcggacaat ttattttcta
     3361 ccagtcgttg ctgcaccatc cgcagtcgca atgatttggc gctggatgtt caataatgat
     3421 tatggactga ttaataacat gttggctaaa ataggtctcg atggaccagc atggttaacg
     3481 gatccatcga ttgcgattta ttctattatc attgtaggag tttggagtgc tattggttat
     3541 aacatggtgt tattactagc cggcttataa gaaattccta aagattatta tgaagcagcg
     3601 gaaattgatg gtgctagtcc aatccagcag tttttcaaca ttacgttacc attagttaca
     3661 ccaacattat tttttgtagt tgtaacaaca gttatcaatg ctttccaagt atttgatgtt
     3721 atttttatga tgattactcc taatagtacc gccatgttta aatcacaatc attagcctat
     3781 ttattctata aacattcatt tattttaaat gacaagggat atggttcggc aatcgttatg
     3841 ttccttttag tgattatatt aattattact gcaattcaaa tgaagttgca gaaaaagtgg
     3901 gtaaactatt aaggaggcta tcaaattatg aaaaataaat ttttttcaaa tgcgccaatc
     3961 catatcatgc ttattttagg tggtattgca atggcattac cttttatttg gatgatttta
     4021 acttcaggga aaacgttggt tgaatctacc caaattccac ctacaatttt ccctgagaaa
     4081 tttcagctaa gtaactatca acaagtactt gatttattac cattcatggc tttttatatc
     4141 aatatatttt taatggttgt tggacgagtg attggctcgg ttttattttc agcaatggct
     4201 gcatatgctt gtgcgcgtct aagttttcca gggaaaaata tccttttcag cttagtactt
     4261 attcaaatga tgattcccgg ttccattttt attactccac agtatttatt agcacaaaaa
     4321 ttgggtattt taaatacaat tccagcatta atattaccag gggtagttag tgcgtttggt
     4381 acgtttttat taagacaatt tttcttaggt ttgcctgatg aattggagga agcggcctat
     4441 ttagaaggtg ccaatatttg gacgatcttt ttcaaaatta tgttgccgct tgctaaatca
     4501 ggattggttg cacttggaat attcacagcg ttgtttgcat ttaaagattt aatgtggcca
     4561 ttgattgtca atacttcaat tgataagatg cctttagctc cgggattagc aaacttacaa
     4621 ggacaatatg ccacgaactt cccacaatta atggcaggtt cgttattagc aatttggcca
     4681 atagttgtga tattcatcgt tttccaaaga aaattcattg aaggaattgc tacaacaggt
     4741 ggtaaattat aaaactatta attagtgatt ggagagtaag tacatgacaa aaattacatt
     4801 tattggtgca ggaagtacta tttttgcaaa aaacgtatta ggcgatgcga tgttaactcc
     4861 aagtctacaa gatgcacata ttgcattgta cgatattgat gaaaaacgac taaaagaatc
     4921 aaatttaatg cttaaaaata ttaataaaaa ttcgaatgaa aatcgtgctg atattgtttc
     4981 ttattatgat cgcaaagaag cgttaagaga ggctgatttt gttatcaatg ctattcaagt
     5041 gggtggttat aaaccttcaa cagtgattga ttttgatatt cctaaaaaat atgggttgcg
     5101 acaaactatt ggtgacacca tggggattgg tgggattttt agaaccctac ggacactacc
     5161 agtaatgtta gactttgcta aagaaatgga agaagtttgt ccaaatgctt ggttattgaa
     5221 ctatacaaat ccgatggcga tgttaaccat gggtgtttta aaagcgacga gtattaagac
     5281 tgttggttta tgtcatagcg ttcaagtatg cgtaccagaa ttgtttgagc atttaggaat
     5341 agccgatcaa tatgacttaa atgactttca atggaaaatt gcaggcatta atcatatggc
     5401 attcttgttg gaaattacaa aaaatgggga agatttctat ccaacaattc gtcagttagc
     5461 tgcagaaaaa ccaaatccac atccagattc tgtacgtttt gaattgttga aacgttttgg
     5521 ttactatatt acagaatcaa gtgaacacaa tgcagaatac catccatact ttattaaatc
     5581 aaaataccca gaattgattg acgaattagg gattccgttg gatgaatact tacgtcgttg
     5641 tgaacaacaa attaatgatt gggaaagcat gcgagaggac attgtaaata atggggagtt
     5701 aacacatacg agaagccgtg catatgcttc atatatcatg gattctatta cgacaggaac
     5761 tccgtcagtg attgcaggaa atgtcttaaa taaaggctta atcacaaact taccgacaga
     5821 tgtttgtgtg gaagtacctt gtttagtcga taaaaatggc gtgcaaccaa cctatgtcgg
     5881 tgaattgcca acacaattag ctgctttaaa tcggacgaat atcaatgttc aagaactgac
     5941 agtagaagcc gctttaacac tagataaatc aaaaatttat caagcagcgt atttagatcc
     6001 acatctatca tctgaattgt ctttaacaga tatcaaaaat ttagtggatg atttaatcga
     6061 agcacatggg gactatttac ctgaatataa ttaaaaagaa gctgaaagag taaggaattt
     6121 tcaattcctt actcttttct tagttaaatt tagtaaaaat attgacaaaa cacttagtaa
     6181 acagttacat tagtgttaac aaaaagaaaa cgcattcaaa ttgtataagg aggagcataa
     6241 aatgaagtgg tctaaaaaaa ttattttagc ttgtatagca ctaggagcaa cgatctcttt
     6301 gactgcttgt ggaaaaaatc aggaagatgc aagcggtaag gtagaaatag agttttttaa
     6361 tcaaaaaaaa gaaatgactc aaacgattca ggagattgct aaagattttg aagcaaaaaa
     6421 ccctgatatt catgtaaaag ttgtggatgt accgaatgct ggtgaagtaa ttaaaacacg
     6481 tatgcttgca ggcgatgtac cagatgtcat taatctttat cctcaaagta tagaattgaa
     6541 agaatgggcg aaagctggtt atttagagga cttaaccgaa gaaccgtatt tagagaatat
     6601 caaaaatgga tatgcacaac gttttgctat tgaggatcgt gtatatagca taccattaac
     6661 cgctaatgtc tatggttttt actataacaa aactgctttt gaggaaatgg ggattcaagc
     6721 accagaaact tgggcagaat ttgaaaaaat agtagctgag attaaagatc aaaacaaagt
     6781 accgtttgcg attgcaggag cagaaggctg gactttaaat ggttatcacc aactagctat
     6841 agcgactgct gctggtggtg aagaggaagc gaacaatgtt tggcgtttct cagaagttaa
     6901 tggaattaat gctgaaagca aagaaatgca aaaagatttt aatcgattag atttgttaag
     6961 agaaccaaaa gctttgcaaa acaactggca aggtgccggt tataacgata cagtagttac
     7021 ttttacaaaa ggtgatgcgt tgattatgcc gaatggttca tgggcaatgc cgatgattca
     7081 ttcacaaaat ccagattttg aagtaggaac ttttcctttt ccagcagatg aagcaggtca
     7141 aagtctaacg attggcgcag gagacctagc cttatcagtt tctgcaactt ctcaacataa
     7201 agaagaagcc aaacgttttg tagaatatat gacaacacct gaagcgatgc agaaatatta
     7261 tgatgtagat ggtgcaccgt gtgctgttga gggcgttatc gagaatactc aggattcacc
     7321 attaagtggt ttaactgaac ttgcttttac tgatcgtcat ttagtttggt tagccaaaga
     7381 ttggaatagt gaaaatgatt tttatacctt aacaacaaat tatttacaca atggcaatca
     7441 aaaagccatg attaacgcat taaatgcttt ctttaatcca atgaaagctg acggaaggta
     7501 ggaaaataaa atgaaaataa aagaaatttt aaatcgttac tgggcaatca tttttgtagc
     7561 aattccaatt attttgcaga tgattttttt ctactttcca atggttcaag gtgcttttta
     7621 cagtttaact aattggactg gtctgactta taattttgat tttgtgggtt tgaacaatta
     7681 taagattctt ttttctgatc cgaagtttat caaatcgatt ggcttcactt taattgtgac
     7741 gctttgcatg attgctggac aaattggttt tggtattttg attgcgcggg cgttgaacgc
     7801 aaatattaaa gggaaaacat tctttagagc atggttcttt tttccagcgg tcttatcggg
     7861 cgtggttgtt tctttagtat ttaaacaaat ttttaactat ggtttaccaa aaattggtag
     7921 tatgttaggc attgaatttt tacaaaccag tcttttagga acaacatggg gagcgatttt
     7981 tgcagtaatt tttgttttac tttggcaagg aattgccatg ccagtcatca ttttcttagc
     8041 gggttttcaa agtattccac aagaaattat tgaagctgct agaatggatg gggcgaatga
     8101 taagcaaatt ttttggaata ttgaaatcac ctacttatta ccaagtattt caatggtatt
     8161 tattatggca ttaaaaggtg gcttaacagc atttgatcaa atttttgctt taactggtgg
     8221 tggaccaagc gatgccacaa catctttggg gttacttgtt tataattatg cttttaaaaa
     8281 caatcagttt ggttatgcga atgctattgc tttagtctta tttatcttaa ttgggattgt
     8341 ttcactggca caattaaaat tatcgaaaaa atttgaaatc taggaggttt cccaatgaaa
     8401 acatcaaaag aaaaaaatat ttctaaatac ttgcttttat tattaggggg cttcatgatt
     8461 ttagttccct tagtttcaac gctattcggt tcatttaaaa caacacccga tattatgaat
     8521 aatttctttc gttttcctaa tccagcgact ttggaaaatt tccgaagatt gttagcggat
     8581 ggaattggtc attacttttg gaattcggca atcatcacaa tcattgcagt agttgctgtg
     8641 acagcaatta ttcctatggc tgcttattca ctagcaagaa aaatgactcg tgggaaagca
     8701 tacggattga tgtatttatt tttaatttta ggaatttttg ttcctttcca agtaattatg
     8761 attccgatta ccgttatgat gagtaaaatt ggtttagcaa atatgtgggg attaatctta
     8821 ctctatctca cttatgccgt accacagaca ctatttttat atgttggttt tattaaacta
     8881 aatgtgccta tcagtctgga tgaggctgct gaaattgatg gggctagtca ctttacaact
     8941 tatttcaaaa ttgttttccc aatgttaaaa ccaatgcatg cgacgactat tattcttaat
     9001 gctctatggt tttggaatga tttcatgcta ccattattaa ttttaaatcg tgattctaat
     9061 atgtggacac taccattgtt tcaatataat tatacgggac aatattttaa cgactatggt
     9121 ccaagttttg cttcctatac agtaggaatt gtcacgatta cactagttta tcttgctttc
     9181 caaagaagta ttatagctgg aatgagcaat ggagcagtga aataaccaat aaattattct
     9241 cattataaag gagttcataa acttatgatt atatttgaca atcacacaca aacatttcat
     9301 ttacaaaata aaaaaattag ctatctatta ggaatcgaag aaaataatta tttaacgcat
     9361 ctttattttg gaaaaaagat tacgcactat tctggtgggt atcgctaccc ccgaacagat
     9421 cgttccttct cacccaacaa tgcaaatgcg caagatcgtt tattatcttt agatacatta
     9481 ccattagaat ttccaggata tggacatggt gattttagag aaccggcgca taatattaaa
     9541 ttaggaaacg gtagtcgtgt aaatgatttt cgttatgata gctacgaaat tcaaaaagga
     9601 aagcccagct tagcgggatt gccagcctta tatacggaag atgatgatga agctgaaacg
     9661 ctgattattc aattgaaaga cgcgattagt ggattgactt tacagttgtt ctacacaatt
     9721 tatcaaaatc acagtgtaat tattcgttct acgcaattag taaataatag tgatgaaaca
     9781 gtggagatta accgcttagc tagtcaatca attgattttc caaatcgtcc actcgagtta
     9841 attcatttaa atggtacctg ggcaagagaa cgtcaaatga ctagagaaaa aattcataca
     9901 gggataaaag tattagatag taaacgcgga tcaagcagcc atcaacaaaa tccgtttgtt
     9961 gctttagtag atgccaaaac agatgaattt caaggagagg catatggatt taatttagtt
    10021 tatagcggta atcacgaaac ggtgattcaa aaagatccat ttgaccaaac acgggtcatt
    10081 atgggaatta attcatttaa ttttggttgg caactaaaaa ctggcgactc atttcaaacg
    10141 ccagaagtcg tgatggttta tagtaatgaa ggtctgaata cgttatcaca gacgtatcat
    10201 gaattgtata atcaccgttt aattcgtgga aactatcgtt tacaagaacg tcccacgtta
    10261 atcaacaact gggaagcaac gtattttgat tttaacgaag aaaaaatcat gaatattgtc
    10321 gatgatgcga agaacttggg cattgaaatg tttgttttag atgatggttg gtttggcggt
    10381 cgtgaaaatg acttcacttc attaggtgat tgggttgaaa cagaaggcaa acttgcttgt
    10441 ggtttggaaa atttagccaa gcaagtgcat gataacggga tgaaatttgg gatttggttt
    10501 gaaccggaaa tgatttctga agatagtgaa ctatttcgag cacatccaga ttgggcattg
    10561 ggtattccag gtcgtgaccg ctcaattagt cgaaatcaat atgttcttga tttttcaaga
    10621 caagatgttc gtgataatat ctatcaacaa atgacggcga tttttgatcg tgtaccgatt
    10681 gattatgtga agtgggatat gaatcgaaat atgacagaag tctattctgt cttgttggac
    10741 tcaacgatgc aaggtgaagt ggctcatcgt tatatgttag ggttatatga atttttagaa
    10801 aagttaacaa cgaattatcc aactatttta tttgaaagtt gttcgggtgg aggcggtcgt
    10861 tttgatgcag gtttcttgta ttacatgcca caaacttgga cgagcgacaa taccgatgcc
    10921 gtggctcgtc tgaaaattca atatggaacc agcttagtgt atccaatttc aagtatgggt
    10981 gcgcatgttt cagcagtccc aaatcatcaa acaggaagag aaacgagttt aactattcgt
    11041 ggcaatgctg cgatggctgg tgtttttggt tatgagctag atctaacgca attaacttct
    11101 gaagaaaaag cagaaattaa agaacaagtt gccttttata aaaagcatcg ccaacttttg
    11161 caatatggaa ctttttatcg cttggaaagt ccgtttgaag gcaatgatac tgcatggatg
    11221 tttgtctcaa aagaccaaac agaagccatg gtcttttatt tccgagtatt agcagaagct
    11281 gcgcatccat tagtcacatt gaaattagca ggattagcag aagaagcaac ttatcaaatg
    11341 gaagatgtaa catttgctgg cgatgaattg atgaatctcg gtttttatat tgactcagaa
    11401 ctacatggtg attatgcgac acaacgcttt tatttgaaac agatatagta gcttgaattt
    11461 acaatataag tgcaacacca aaagagactc attccaaacg aagaaaatat gttttattta
    11521 cacgcattta ctaaaaagca gcctgatttg aattgggaaa atgaagaagt acgtgaagaa
    11581 atctatgcaa tgattaacta ttggttagat aaaggactag gcggatttag aatcgatgcg
    11641 atattaaaca tcaaaaaaaa actagagtat ggcatctttg aatctgatgg agaagatggg
    11701 ttagccttca ttgggccctg gattcttaat cagtcgggca ttgaagtgtg gttaaaagaa
    11761 atgagagagc ggacatttaa accacataat agtatgacgg tagcagaagc cgatgttcct
    11821 aatgaacgtt tagatgaata tattggtgaa gatggctatt attcgatggt ttttgatttt
    11881 agttatacgg atattgatgt acctgaaact ggtgaatggt ttaaatatag ccaatggaca
    11941 tggacggata tgcgtaccaa tatttttacg aatcaattag ttacgcaaga taaaggttgg
    12001 ggcgccttat atttagaaaa ccacgatcaa ccacgttcaa ttaataaata tattccagaa
    12061 gaatggatca atgattatag taaaaaaatg ttggcgacgc tttttatgtt actaagaggt
    12121 acccctttta tttatcaagg acaagaacta ggaatgacca acatagaaat ggcatcatta
    12181 gaagattttg atgatgtagc tacgcattct cagtataaac gggcattaga atatggattg
    12241 gcaccagagc aagcattgaa agctgtcaat aaacgaagtc gggataattc tcgcacacct
    12301 atgcaatgga atacgcaaaa aaatgccaga ttctcaactt ctgataatgt atgtttaaaa
    12361 gtaaatccta attatccaga actcaatgca gaagctcagt taaccaatca acagtcggta
    12421 ttcaattatt atcatcaatt aattaaatta agaaaaaata gtgtatacaa agacgtgcta
    12481 atctacggac aatttctacc agtgaaagat aaaaatgaac atattttgct ttatgaacgc
    12541 caattagaag ataaaatcgt attagttatc ttaaacgtta cagcaacaga acaagaatat
    12601 tatgtagatg aacagtacca acaagtatta atcaataatt atgaagatgt tttattagat
    12661 caaagtcgaa aattgcgttt acgaccgttt gaaagtattg tattagctaa ttatggagga
    12721 caattatgaa aattaaaaac gaagcaatgc tcatcaccta tgcagatagt ttaggaaaaa
    12781 acatgggcga attaaaacaa gtcttagaca aacatttaca aggtgttatt ggtggtgtac
    12841 atctgttgcc tttttttcca tcgacaggtg atcgaggctt tgcgccgagt gattatacga
    12901 cagttgatcc agctcttgga acatgggaag atgtggaagc attaggtgaa gattattatt
    12961 tgatgtttga ttttatgatt aatcacattt ctcgtgaatc aaaatttttc caagatttca
    13021 aaaaaaacca tgagcagtca ccatacaaag aaatgtttat ccgtattcat gaatttttcc
    13081 cagaaaatcg accaacacaa gaagatattg atttaatcta caagcgtaaa gacaaagcgc
    13141 cgtttcaaac ggtagaattt gcggatggta cgacagaaga ggtttggaat acctttgggg
    13201 aagaacaaat tgatttagat gtgaccaaag aagttgtgaa agaatttatt cgagaaacca
    13261 tcaaagatat ggcgaaccat ggctgttctt taattcgatt agatgcgttt gcttatgcga
    13321 ttaaaaaatt agataccaat gatttcttcg tggaaccaga tatttgggaa cttttagacg
    13381 aagtgcgtca agaagcagcg aaatatgacg tcgaattatt accagaaatc catgagcatt
    13441 attccattca aatgaaaatt gccaatcatg attattatat ctatgacttc gccttgccaa
    13501 tggtcactct gtattcactt tatagtggaa aatcagaacg tttagccaat tggttgaaaa
    13561 tgagtccgat gaagcagttt acaacattgg atacgcatga tggaattggt gttgtggacg
    13621 ctcgtgattt attaacagat gaagaattgg attacacctc tgaggaattg tataaagtcg
    13681 gggcgaatgt gaagaaggtc tattcaagtg ccaattacaa taatttagat atttatcaaa
    13741 ttaacagcac ctattatagt gcattaggcg ataatgaccg tagctatctg ttagcacgtg
    13801 cgattcaagt atttgcgcca gggattccac aaatttatta cgttgggtta ttagcaggaa
    13861 aaaatgatat tgaactgttg gaagcaacga aagaagggcg taatattaat cgtcattact
    13921 atgatttagc cgaaattgaa gaagaagtgc aacggccagt gactcaacaa ttatttgcac
    13981 ttttaaaatt tagaaatgaa tctgcggcgt ttgatttgga tggaacgatt gaagtagcaa
    14041 cgccatcaga atcagaaata gtgattacac gtaaaaataa aaacggtagt gatagtgcaa
    14101 cattaacggc taacttggat acgaaagaat ttatcattga gtctaaagat ataaaaattt
    14161 tcactagtgt tgcattaaaa ttttaaccta ttccatagaa caaaaaatcc tttatactag
    14221 cacttggatg acttatccaa gaccaataaa aaggactcat acatggataa gtataaaaca
    14281 aatacagcat ttaataaatg gttttctgcc ataaaattag gaaaactttc tgtcaactcc
    14341 caaaaatgta tttttgatta caattcgtat cgtaaaaaac tgtcttttga agctgtgctc
    14401 aagctctttc tctacgcagt taatgaagaa aaagaaagtt tgcgtgattt gagtacagct
    14461 cttatcgacc gatcgctcca actagaaacc gatgtgtcat cgattagtca tacccaattg
    14521 tctcgagcat ttaatgcact tgaacctaaa gtgttagaag aaatttttca acaactgtta
    14581 gaaaaagttc aacatcaaat caaaccaacc aagcgaaatc atctgtatct gattgattcc
    14641 agtacgtttt cgcttagttt aaaacgtcat aagtgggcga ctttccgtca aacaaaatca
    14701 ggtgtcaagt tacacttaaa ctattgttat atggacgata ctacgatgta tccaactgat
    14761 tttaccttaa caaatgccca tgaacatgat ctcaatcaac taccagtatt ggtgaatcaa
    14821 ccagaggcaa cttacgtgtt tgatcgtggg tattaggact ttgaaaagat ggatcagatg
    14881 cattgggatg gctatttctt cgtcactcgg attaaaaaaa acaccaaagt tcacgtgata
    14941 gatactctgg aaacatcgcc agaaacagaa attctacgag acgagctggt tcgtttagga
    15001 tctaaaacct atctaaccgc caatttccga ctagtcactg ttcaagataa gaacggacgt
    15061 gtgtttcaat ttatcaccaa tcgaatggac gtctcttcaa aagaaatctc tgatatgtat
    15121 cacgctcgtt ggcaaatcga attgtttttc aagcacatca aacaacacat gaccattaaa
    15181 accttctttt ctcaaagtga aaaaggcgtg cagaatcaat tgattttaac gatgatttcc
    15241 gctctcctca cgtttctcat caaattggag acgaaaacgg aaaaatcagt gttccaaatc
    15301 aaacgattct ttcgttattt actgtttcag ccctttgaat gttgtctaga aaaattaatt
    15361 cccacatgag aaaaaagaaa tttggctcgt tacttttggt tttcagttga ataacagata
    15421 aaaaattttc tggaaaaagt catcctctgc gtcagcacag ttttttttga cttattttca
    15481 gaggaaatag ttttcagaat attctaaaat gttttatgca acactagtga tattttttag
    15541 aattagattt ctaatgtgca ttttttgagt attaaggagc aagtatacaa agatttataa
    15601 agctgattaa atttgaataa aaatatgcag gaacgctact atttttagta gtgttctttt
    15661 ttatatttga ataaaaaatg tggtggttaa atggtggtta taacaaaaaa tgaattaatg
    15721 aaattaggtt atgggaagta tcagtctgag agaatcatac gacaggcaaa agcaattatg
    15781 gtttcaaaaa gctataccta ttacgaaaat agaagattag gactagtacc tgttgaatct
    15841 gtagaagaag ttttaggtat gaagatagag gtagaggagg attttcagaa tcatggttaa
    15901 ttttaaaaaa gataaaaatg ggaaatatca ttttactgct agtttgggat tcgacaaacg
    15961 aacagggaaa agagtacaaa aaaacgtaga ggggttaaaa cagttaaaga agaaaaaaag
    16021 cgtataccga acttgtttct aattatggaa aagaagcaga aacttctcaa agtactatgt
    16081 tgtttgagga gtttttttat aaattattcc taccttatta tcaagggaaa gtagaagaaa
    16141 gaacatataa aaatcggtta tctacaatca aaaaaacttt tcttatttct ttaaaatgga
    16201 gttaagagaa atacgtccaa ttgacattca aaagtggcaa aataatttat tgagcaaata
    16261 taaaaattct tatgtaagaa acatgtatgg gatttttcag atgtcattag atcgagcagt
    16321 tgttttgtga ctacttgaaa aaaatcctgc aaaagttatt ggaaatgtga agaaaaggaa
    16381 aactacagtt gatttttgga caaaagaaga atttacaaaa gttatttcaa ctttttatat
    16441 tgatgatttg taccaacatt ttggttttat ttgtatgtgg ttacttttta tgaccgttat
    16501 gcgtttggga gaagccactg cattaacttg gaaagatatt gattttgaaa ataaaaactt
    16561 gcgtgtgaat aaaacactct attataagag agccaaaacc tatgagtttg tagaacccga
    16621 aacggcttct agtattcgta caatcgaact agacgacaat acaattacct ttttaaaagc
    16681 ttggaaggag cgtcaagttt caataggagg catgtcgttt gtactttctt ataatggaac
    16741 acctactcag aaatatacaa tccgtcatat tatgagaaga catgcaacga tcgttggtgt
    16801 tcatataatc cgcatacacg gattaaggca tagtcatgct tctttgctta tatcacaata
    16861 aaaagatgca cttcgaatta aagaaaggtt aaaacatgct gatgtacaaa cgactttagg
    16921 aacttatggt catttgtatc taaattcatt gagagagata acaaatgatc ccacagatta
    16981 tatccaaact aatttttcta aaatcaaacc gacacctatt tacgataata aaaaataaat
    17041 gataaacaaa agtaggatca caccaaaaga aacacactag aaaaactata atacaggctt
    17101 ttctagcgtg ttgtttctta tttccgccta tttatacatt atactcataa agcatttaat
    17161 gcatcgatcg tagccgcatt gtctatatgg gtatataaag ttgttgtatt ggtacttgaa
    17221 tgtcccaatt gttgggcagt taataccaat gaatttgtct gttggtagag tctagtagct
    17281 aatgtatgac gcagtttgtg agggctgact tgaattctaa agccttttga atattttgct
    17341 accatccgtt cgattgcaat accggatata cgcttggctt ctccttggta aattgctaga
    17401 aataaagctt tttcgttttc tgttacttta tatcgttctt tccgaatagc tagataatta
    17461 gctaaatatt ccattgcgaa tgctgctata ttgacagcat ctcttttatt tccttttcta
    17521 gttactacca cattattctt atctaaagat aggtcatcta aattaatatt tataacctcg
    17581 gagagtctca atccagatcc taaaatcagt gcattgatcg ccaggtctct ttctacatct
    17641 cgttgataat agatcaaagc tcgtttactc aaagtatttt tatattcatt ggcaatataa
    17701 tctagataat tttgtgtatc cttatctaga aataattttt tctcaatggc attggcacgt
    17761 gcagctaacg tagttttatc tgtgatggtt gctacttgat ccataggatt attgtctaag
    17821 tatggttttc ctagaggatt attggaactt ttcgaaagat atttaaatag aacctttaat
    17881 gccgtgatat ttctattgat agtagaagta gatagaccta agttattatt atctttgagc
    17941 ttagtttttg ttgtctcttt ttttacattt tcttttgtgc gacgtttcaa atgagatttg
    18001 tacaagttta ggtcataggc agttaactgt cttatcgagg tgatagaagt atcaggaacg
    18061 atagactcac tcagaagcca ttcataaaag agcttataat tttttagata ttctaaagtg
    18121 gttcgaggtg attgatcttt atcctcacga tcttgaacaa aatcttttat ataatcgggc
    18181 atatgaagta tgattgtatc tattttttga tatatttctg tatttttcat gtcattcatc
    18241 ctttcaataa gtaggggaga agagtatctc tataattgga ctataccaat tatagaatgt
    18301 tttgtcaatt ggtatgctct aaaatttatt aatttgtttc aaaaaaagca tataaacagg
    18361 tatacgttta ataatttaaa ataaatggta tacataaata gggaaggaaa tagaagggag
    18421 caatctaaat tttttgaatt ttcttaatta attatataga aagaacaatc tttctataga
    18481 gttagacatg agagggacta tgcttgattt aaaatcaaca agcgtatata ctgtatatac
    18541 aaagaaaaag gagggagaag actatggcaa ttaaagaaag aaaatttagg gaagtgggga
    18601 actcagtagt attaactatt tcaaaggagt ttcttaaaga aaatgggtta aatcccggag
    18661 atacggtttt tttagatgaa gaaaaacttc gagcggcaat tacaaaaaaa caagccttat
    18721 ctgatgaaat tgatttagca atatctcaag cattaactga atatgatact acttttagag
    18781 agcttgtcga taaatgagta ttcattacct agaagccaaa gatattataa aaatgaatgt
    18841 aatccaaata aaaaaatact ctcctaatga accccttggt gtaaaggatg cgaatgcttt
    18901 agaaatgtgt gtagggcaac ttcgagcctc agcttttggt gaagaggttt atccttcgat
    18961 ttatgaaaaa gcagctatcc tacttataca attgataaag aaacatcctt ttcacaatgc
    19021 aaataaacgt actgctttct tagctacttt tgtctttttg aaaatcaatg gacagctttt
    19081 agctattgat caaaaagatg ctgtaaattt agcggtatat attgctacgt atgataagga
    19141 tttcgatcaa ctaaaatatg aagtgatcaa cactataaag acacatacgc agcccattta
    19201 aggagttact gtatgtgtct ttatagtgtt attagctgct atagcgaaat aattgaagta
    19261 aattacaaat agctataatt caaatccaag tatatagaaa acgtaaattt tctatatagt
    19321 tggattaaga taacgactat ttattttatc atatttttac tgtaccctat acttttactt
    19381 ggtatattta tgaataatcg caaatttacc cctatactac tagtttgtaa gttagattaa
    19441 taaaaatact aaagttattt gttcttttat taaatacacc tacaacttat aaattgatgg
    19501 tatttagata acgcgaaaga ataaaaataa cagctgatag taaagtttgt tgacgattgc
    19561 tactcaatcg aaagtgagtt agtgcgtatg aacttgcttc tgaaaactta tgaaatgaaa
    19621 gaccttttac atcttgcaga aatcgttact gggattaaac taagcaataa aaactaatgt
    19681 tcccctcatt ctttgaactt ctactatttg atttatttat tctgataaat gacgatttca
    19741 ccttcaggat cttcaaatcc cgtatagaat ttatttaaga tctcttcagt atcagtaata
    19801 ggataggcga taggccacat accctttgat ggttagaata aactgctcaa aatctgtatc
    19861 gtatgttggc tttagcatat taacaaaggc tatctccaaa ttataaacca taagcgttga
    19921 atcgttctta acaatttcaa ttcttcctaa cccaaagtca gaagatataa ttaccggact
    19981 tgccttaccc ttcatgtggg ttgttgagat tccatattta aagggaattg tcggtactat
    20041 cggcggtctg aaaaacatcc caaaaataaa aaaatctttc ccctgctagt ctcctaagtc
    20101 cctttgcagc ggatatggca ccataatctc attttatcga agtgagtcat ggtttatctg
    20161 ttggccaacc aaaattgata caatctaacg atgcaccctc tacggcattc taggggagtg
    20221 cacttgcatt cacccaataa aaaccggcag ttagcaaaga acttatgtag tcgtatgttc
    20281 ttactgttaa catacaagag gtctcctttc cacaattgct tagcagtaaa cgggaattta
    20341 caaagctaat ctcttccatt ttcttatctt tgttctaaaa gtcccaaatg gagcaactgt
    20401 atttacatga ataaatttat atacttccca tacagccgtt ttggttgcct cgtctgccca
    20461 ttttcttttg tgtgcagtga atagatcttc atcactcatt gaatcaatca tcatgttaat
    20521 atcatcaata ttacgattga gaatttcctc taattctttc aatggtagat gtgcataggt
    20581 atttgtaaac cacttatata actctcctaa ctgattccat ttaaattgat cagaaggcgt
    20641 tttaacagat aatccatttc tttcatcatt ttcccatttt agaattaaat tcgtccaacc
    20701 aacttgatat gctaaatttt cagcaggtgt tctatccact tcctcaactc ttttatcctt
    20761 caattcttca ggaatagttt caaattctaa aatatattta gtataagtcc tatttatttc
    20821 tttttttaat tcttctttat ttttatatgt tctcattata ttacctccat aaattcctaa
    20881 ttgtctcctt taattcatct ataatttcat ccacgatatt ttaatccgtt ctacaatgca
    20941 tatctgatat gcattgactg tctaactcat atgtgaatga tttataaaat atcccaacgt
    21001 ctcatctaaa gaaatgttga tcgtcagcaa ggagctaaaa aatacgaata tatttctttt
    21061 gtagtaaaat cggactggtt tgcatatcat tttcttcgta aatatcaaaa tcatgttaac
    21121 tactatcaat tactaataaa aactaccact ttaagcgtta agaactgtta agtttagtta
    21181 agtgaggata gttcacaaaa tccattgtta aacttcacga aagtggtaaa actcaaaatg
    21241 ctttatatag gattacagca tcgctctttc ttcgattgcg cgttgggtaa aaaatattat
    21301 gaagtaaaaa ttgacgatga cacgttcctt acggctcatc agatgaaaca gctacaaaaa
    21361 cgaaatgatc aactcgaaga aaatttaatt ctaaaaaagc gattgccata ttcacgcctc
    21421 gctcgacgaa ctattaaagg tcaagattta cctgaagatc atccttttta ggaaattgaa
    21481 gctttttatg ttgcacaatg catttataat actacaatga tgttttcacc agatattctt
    21541 ctagggtgcg gtgtaatgaa acagatacac ttgcaaaaga aaattcaccg cgaatttact
    21601 aaaattatga ataattatgt taatcttccg aaattttttt ccaaaattaa gggatcaagc
    21661 tggtgttata gattgtttaa ggttggcaaa aaaataactt ctttttaaac aattatagaa
    21721 aaccgatact ctgttaagtt ggttgacacg gtatcgattt ttatgacttt cttattctga
    21781 aacttcacta acggacagta cctaaaaagt ctatagtatg gacgtttacg agtactattt
    21841 tatcaaaaat gctgctcatt tcaacttata tgttttagtg aactaccccc acttagctaa
    21901 acctgacggt tcttaacgct tgaagtggga gcttcttggg aacagagcgt acttga
//
LOCUS       DAIGTA010000049        21282 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.050, whole genome shotgun sequence.
ACCESSION   DAIGTA010000049 DAIGTA010000000
VERSION     DAIGTA010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.050"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            133..507
                     /locus_tag="NOB43_001979"
     CDS             133..507
                     /locus_tag="NOB43_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0982828.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="NOB43_001980"
     CDS             complement(621..1250)
                     /locus_tag="NOB43_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0982829.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="NOB43_001981"
     tRNA            complement(1384..1456)
                     /locus_tag="NOB43_001981"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="NOB43_001982"
     tRNA            1670..1743
                     /locus_tag="NOB43_001982"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
     gene            complement(1881..2045)
                     /locus_tag="NOB43_001983"
     CDS             complement(1881..2045)
                     /locus_tag="NOB43_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982830.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2340..3668
                     /locus_tag="NOB43_001984"
     CDS             2340..3668
                     /locus_tag="NOB43_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HCI0982831.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3870..4703
                     /locus_tag="NOB43_001985"
     CDS             3870..4703
                     /locus_tag="NOB43_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCI0982832.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4719..5456
                     /locus_tag="NOB43_001986"
     CDS             4719..5456
                     /locus_tag="NOB43_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HCI0982833.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5611..6579)
                     /locus_tag="NOB43_001987"
     CDS             complement(5611..6579)
                     /locus_tag="NOB43_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCI0982834.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6811..7644
                     /locus_tag="NOB43_001988"
     CDS             6811..7644
                     /locus_tag="NOB43_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCI0982835.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7678..8517
                     /locus_tag="NOB43_001989"
     CDS             7678..8517
                     /locus_tag="NOB43_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0982836.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8543..9103
                     /locus_tag="NOB43_001990"
     CDS             8543..9103
                     /locus_tag="NOB43_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0982837.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9302..11023
                     /locus_tag="NOB43_001991"
     CDS             9302..11023
                     /locus_tag="NOB43_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HCI0982838.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11188..12330
                     /locus_tag="NOB43_001992"
     CDS             11188..12330
                     /locus_tag="NOB43_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0982839.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12346..13557
                     /gene="thiI"
                     /locus_tag="NOB43_001993"
     CDS             12346..13557
                     /gene="thiI"
                     /locus_tag="NOB43_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCI0982840.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14130..14777
                     /locus_tag="NOB43_001994"
     CDS             14130..14777
                     /locus_tag="NOB43_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI0982841.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="NOB43_001995"
     CDS             15170..17815
                     /locus_tag="NOB43_001995"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCI0982842.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="NOB43_001996"
     CDS             18125..19438
                     /locus_tag="NOB43_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCI0982843.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVITGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="NOB43_001997"
     CDS             19428..20081
                     /locus_tag="NOB43_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0982844.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="NOB43_001998"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="NOB43_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCI0982845.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="NOB43_001999"
     CDS             20978..21178
                     /locus_tag="NOB43_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0982846.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7185 a         3551 c         4445 g         6101 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc tttttctttt
     1801 attattatga tgaatcaagc tttctgtttt tgtcacgtat gttgtaatct ttacgaaaga
     1861 gtagagttgg ctactcataa tcaaccatac ttcccatcat cgctaaatac gaaataaatc
     1921 agcattccta caccaatcaa agcacaagct gcaccaagaa aagggatgac attcccaaag
     1981 ttatctgtat tcataagtat gccaccaccc acaaacaaaa agccgccagc aatcaggttt
     2041 ttcattttat tcatctcctt tcttacgtta tagtatttcc ttctttcaat gagtattttg
     2101 aaagctatct tattgtatga tgttcttcta ggcctcttct ttattataca ggccattttc
     2161 gttatctcat agaaatattc ctttttatct gaaaactatt gtataccgta tgacattttt
     2221 cttcatgaag ttgtaagtat attctcattc aaatgaaaat ttcatcatag aagagattgt
     2281 atttctaaat tcttaagagt aaaatacgaa gtataacttg gatttggaag gatgattgga
     2341 tgaaagctat tacgcctgat atgacaacaa aatttaacaa acagtttcaa gcaaatatca
     2401 aacagcaggc attgcagcgg gcagttgtga agaacggaat tactgcttct gctgaaaatg
     2461 tttcagcaca tgtggagaat acaccggtat tttctataga tttggctacg gggaaagtgg
     2521 ctaatcaaat gcaatcgggg cgttgctgga tgtttgctgc actgaacaca ttccgtcata
     2581 agatgctgaa tcaattccat ttaaaagagt ttgaattatc acaaaattac acttttttct
     2641 gggataaata tgaaaaggca aattatttct atgaaaacat cattgcaaca ggaaaagagg
     2701 caatcgatag ccggaaagta gctttcttac tcgctactcc tcaacaagat ggcggccaat
     2761 gggatatgat cgtttcatta ttccaaaaat atggcgttgt gcctaaatcg gtgatgccgg
     2821 aaagtgcgaa tagttcaaat tctcgagatt tgaataacta cttgaacaaa ttactgcgta
     2881 aagatgcagt agtgttacgg aaaatggttg ctcaaggaga aacattagac gctattgaag
     2941 aaaagaaaga agaaatgcta gaaagcattt ataacttctt agctatctca ttaggaacac
     3001 ctccaaaaga attcgatttt gagtaccgcg atgaagaaaa gaactatcat cttgaccgag
     3061 gactgacacc acaaattttt tatgataaat acatcggtgt aaaattagat gattatgtta
     3121 gcgtgatcaa tgcaccaaca aaagacaaac cattcaatcg ttcttataca gtagagatgc
     3181 taggaaatgt cgttggcggg aaagaagtca aatatctgaa tgttgatatg gaaactttca
     3241 aaaaattagc gattgctcag cttgaagaag gagaatctgt ttggtttggt tgtgatgtag
     3301 gtcaatcttc tactagaact agtggcatca tggccttaga tgcttattca atggatgatc
     3361 tatttgatac ggattttaca atgactaaag ctgaacgttt agattttgga gaaagtctga
     3421 tgacccatgc gatggtattg accggtgttg acttagtaga cgggcaatca acaaaatgga
     3481 aagtcgaaaa tagctggggc gaaaaagttg gaaagaatgg cttctttgtt atgagtgatg
     3541 cctggatgga cgaatatacg taccaaatcg ttgtaagaaa agatttattg acgaaagagc
     3601 aattaaatgc gttcaatgaa gaaccaattg ttctatctcc gtgggatcca atgggtgctt
     3661 tagcatagac gagtatttca atgaagagta tgtagtaaag ataaaaagag ctggcttaag
     3721 ccagctcttt ttatctttaa agtccattcc ctgtttttta tggtccctgt gctataattc
     3781 taaataaagg ataaggattg gaaataatcc ttttatcatt aaaaatatga tgacgaagta
     3841 gaataaaatt gggagtaggg gggaaagtca tggatatcca aactgtttta tctgatctga
     3901 aattaaatgg taaagtgatt ccagttgttg gtggcgatgt taatcagacc tatcgtataa
     3961 aaaccgaaca tcgtgcttat tttttaaaaa tccatccgaa tgtaaaaaaa ggattttttg
     4021 aagcagaagt agacggatta aaagaactgt cagcattcgt acgtgtaccg gatacgtata
     4081 tgctaggtga aacaagtgaa ggcgcttatt tgttaatgga atggatcgag ccgggaaaag
     4141 gggatcaacg agatcttgct gcagctttag ctaatctcca tcagcaaaca gcgccacaat
     4201 ttggttttcg taaagataac tatttgggta cacttgttca gaaaaattct tttgaagaag
     4261 attggtggac ttttttcttt aaagatcggc ttgaatccca gatttctttg gcagaagaaa
     4321 cgaatcgatg gaatgtacag cgtcaagaaa agtatctgcg atttaaagaa cgtgtattga
     4381 aatcggttga accaaaaaag atcactccac gcctcttgca cggagacctg tggagtggta
     4441 atgtgttctt tgaccagcaa gggcatccag tttttgtcga cccagctgtt tcttatggga
     4501 atcgggaaca agatattgca atgagccagt tattcggtgg tttccgaccg gaatttttag
     4561 atgcttatca aactatattt ccattagaaa agggatggaa agaccgactg ccgatttacc
     4621 agttatatta tcttttggca catttgaata tgtttggaga aagttacggt tcccaagtag
     4681 atcaattact agaaaatttt taagaggagg gcgtgttttt ggcaaaaaaa tataccaaaa
     4741 agcatgaagt ttcatattat gagtgtgaca tcaaccaaac gatgacattt ccttcgatgt
     4801 taggagtagt tatcaaaacg tctgaagatc aaagcgacca gttgggaaga ggcagtgaat
     4861 tcgtcaatag ctttggactt acttgggtca tcacgaatta ttccatggag attaatcgtc
     4921 tccctagagt cggtgaagta atctcagtaa cgactcaagc catggagtac aataagtttt
     4981 tctgttatcg gaacttctgg atccatgatg aagatgggaa agaattagtc aaaatagaat
     5041 ctgttttcgt attgatggat tttgtgaatc gaaaaatgag cagtgttaat gaagagatca
     5101 ttgctccttt tgagagtgag aagatcaaga aaatcaagcg tcaggaaaaa attgaaaaga
     5161 ttgattcggg cttcatgttg ccatatcgtg ttcgttttta tgatatcgat agtaatcagc
     5221 atgttaataa tgcgatgtat tttaattgga tcattgacgt attaggatat gactttttga
     5281 ctacgcatgt tccagaaaaa gtaattattc gatttgataa agaagtagag tacgggaatg
     5341 agatcgaaag ccattttgaa caaatcccta tcgaaaatgg tgtcaaaaca aaacatgaaa
     5401 tccgaatgca agaacagctg tattgtgaag caaatattat atggaaaaat aaataaaaaa
     5461 gaggttgtga cagaaggggg caacttcaag aaataagaag aaatttacga aaattgtttc
     5521 tcaaattttt gtaaattttc gacttagttt tcgaagaagc tatttttgtc acagcctctc
     5581 tttttaagtt tagctattag ataatgatgt ttagttttgg ataaacgaaa tcaattcttc
     5641 acccgacaaa ccatagttta cagcaatcaa tagttttaaa cgtgcttttt gactattaat
     5701 actgttacag aaaataatcc ccattttttc tagttctttt cccccgcctt cataatcata
     5761 aacaggctct gcgattccat tgaaacaacg agaaacaagt actacaggga ttttttggac
     5821 aagaagcttt tccaaagcag ctaaggcttg tggagggaga ttccccgcac ctaaagcttc
     5881 gattaccaaa ccgtctactt tcgtatgggc gatggcttcc aataagtccc cttgcatccc
     5941 agcatatgct ttaacgatcg ggatagtccc atctacagcg gaaatgtcca gtcgctttgt
     6001 ttctaaaagt tcctgcaaga ataaaattcg attcttagtt actaagccga tgggacccaa
     6061 tgtaggtgtt cggaaagtag caacatttgt ggtatgggtc tttgtcacgt agcgtgcaga
     6121 atggatctca tcgttcatga ccaccaaaac ccccttatct agcgcttctt cacaacttgc
     6181 gacacgaatc gcactttcaa aattataaag gccgtcactt ccaagttcat tacttgaacg
     6241 cattgcccca gtcaaaacaa ttggtaattt gttgccaatc gttgtatcaa gaaaaaaagc
     6301 agtttcttct aatgtatctg taccgtgtgt gatcaccact ccggatatac ctgatgcata
     6361 agcggacaag atacgttctt ttaataccaa catgtgagaa ggcatgatgt gtggtgaggg
     6421 aagattgaag atatcttcaa ctaataattc tacatgcttg gggattgtga tttctgcatc
     6481 taataatggg tttgccacat caggactaac accgcccgtg agcatgtttt ctttcatggc
     6541 gatcgttccg ccggtgtgta gtacaagtat ttttttcatt ttacagactt ccttacgaat
     6601 aattttgcat agccgttaaa tcttattgta tactatataa aagagttttg ctatcagtga
     6661 agaataacga atagcctaac ttatcataaa aaagctgacc ttattaaaat ggaaaagact
     6721 caaccttgac ctcctaatac aatggagtat ctggttgagt ttcttttaca agaaagcagc
     6781 caaggaaatc aatcacgaag gtggccggaa atgatcagaa tcggattaac atcgtttaaa
     6841 gaacatgaca aattaactgg taaaaagaat aacactcttt atgaatatgc agggtttcta
     6901 cccttagtgg aattagatac tgcctattat ggaattcccc gaaagtcctc agttgagaat
     6961 tggataagtg aagtacctga atcatttcgc tttgtagtca aagtctatca aggaatcagc
     7021 ggtcaaggag actggaagcc ttattatcag accgaagaag agatgattgc gcatttttta
     7081 gatgttatgt cgccaatggt agatgctgga aagatgtttt gctttttagt ccaattcccc
     7141 tcatcattca aatgtacgaa agaaaatgtc cagtacttgc gcaaacttag aaagtggttt
     7201 gagggttatc ctgtttctat agaattgcgg gattattctt ggtacagcga tgaatttctt
     7261 gaacgtacaa gaaactttat gtctagagcc gctttttctt tagccatcat cgatgagcca
     7321 cagttgctga atacaacgat tccttttgat ccatttgtca ccaatccgaa ctttgctctt
     7381 tttcgattcc atggtaggaa tgcgcaagga tggcaagcaa atgataaaga gtggcgtaaa
     7441 aaaagaacgt tatatcgtta ttcagaaaaa gaactgcaag aactagcaca tgaagtcaaa
     7501 gtagttgatt ctaagacaaa agaggtaggt gtgattttta ataataattc tggtggtgat
     7561 gcggctgaaa atgcattagc actgcaaaaa atattaaata tcaagccaga tggactcaat
     7621 ccaacccaaa tggatctgtt ttaagggctt attttattca agaaaggggc gaagtctatg
     7681 atcaaagcta ttttttttga tattgacgga acattggtca ccaatcgttc aaaagcgttg
     7741 gaatcaacaa aacaagcaat tgaatatgct cggaaaaacg gcattttatg cggtgtagca
     7801 acggggcgca gcccagtaaa gatcaaagaa atcattgatg aattggaatt agatatgtat
     7861 gtcgtgtata atggtcaact ggtttttact gcagatcgca cgattatcga ccaccctttt
     7921 gaacaaaaag tattggaaca tattgttgaa tttgcagatg agaaccatcg acaaatcgtt
     7981 tttggtgcga gaaatcggtt agatggatca acgacgatgc tattaggaca atcgattttt
     8041 atcaagcgac tagtcagctt tttaccgcgt aaattcccgg tacgtctgat gaaaaaaatc
     8101 ctccaggttt ttagccctca ccgacaaaag gatcgttatg aaacgttaga gatattaaaa
     8161 gaaccaattt atcaatgtat attgctcagt ccggagtcag aacagaaaaa gttagaacat
     8221 cgctttcccg agtgtacgtt tcagcgttca aatacgtata ctgtagatat catcccaaaa
     8281 ggtggttcaa aattactagg catccaagct ttcgcaaatg ctgtcgaaat tgaaatggaa
     8341 gaaattatgg cattcggcga tcattacaat gatatcgaga tgctgaaagg tgtaggaatt
     8401 ggagtggcca tggggaatgc tcagatcgaa gtaaaacatg ctgcagactt tgtgactcaa
     8461 tcaaatgaag aagatgggat atacgaagga ctgaaacact tcggtctgat ttattagtca
     8521 atgaaagaag gaaaaaatca gtatggaagc agagacacct tttcaaaaag tagaaacatt
     8581 ccacaaaact tttgatccaa gaagaccaga gatacccacg gcttttacag aaaatgaagc
     8641 tcatacacgt gctgcgttca aaatagaaga acttgttgaa tttgttgcag ctacttcacc
     8701 taataaagaa caactgcatg aagctgttat gctgctgcac gaagcattag ataaagcaga
     8761 agaaaaaata cttggtaaaa cacagtgggg aagtgatccg ctggttgaac aagtagatgc
     8821 actgacagat atcctttact ttacttatgg ttctttttca ttactaggaa tagtgcctga
     8881 tcgaatattc gaaatcgtcc atcaggcaaa tatggggaaa ttatttccag atggaaaacc
     8941 tcattatgac cctgtaacaa ataaagtgtt gaaacctgaa aactggcaga tggaatatgc
     9001 tccagaacct aaaatcgcgg cagaaatcca acgtcagatt caagaagcga ttgctaagaa
     9061 gaaatccgct gatataggca tgtgcacaaa tgaaaaagag tgatcagagt ttcactattt
     9121 ttgttatctt tatacgatgg aaaaacaaaa gattttcgtt taagttagtg aatgcatgaa
     9181 aatagtatgc tataatctag aatagatgtc ttttgcacga gagacgtatt atttggattt
     9241 atgccaagca gaacgccatc tgttgcataa aagatgcata ctgaaaacgg aggaaccata
     9301 aatgggaaat aatgttatca tcggaatcgt cattgcaatc attatagtcg ccattgtcgt
     9361 ctttttggtt agttacttga tgaagaaaaa aaaccaagat cgattggatg ccttagaaaa
     9421 acgcaaggaa gaattatttg acttgccagt gattgaagaa gtcgatgatg ttaaaaaaat
     9481 gcatctggtt gggcaaagcc aaaatacctt tcgtgaatgg agtcaaaaat ggaatgacat
     9541 atctacttcc tcgttcgctg aactagaaag tcaaattttc gaagtggaaa acctcaatga
     9601 aagttttcgg ttcttaaaag gaaaaaaagc agttgttgaa gcagaagcta caatggacca
     9661 aatggagaaa caagtgacgg aaatccgtga aggtctaaag gaattgcggg aaacggaaga
     9721 acgcaactca ctagctgttc agcaggcact tgacgtctat gaagaactga aagaaaaagt
     9781 cagagaagac gagcatgaat acggaccagc tctttttgaa ttgcaaaaac agatcaaagt
     9841 gatcgaaaaa gaatttacgc agtttgtgac tttaaacact tctggagacc ctgttgaagc
     9901 ccgcgaggtt ttggataaag cagaaaaaca tacgtatgaa gtggaagctc tgatgaaaaa
     9961 aattccaccg ctgtatgagg agctccatac cactttccct gaacaacttg aagaaatcag
    10021 tgatacttac gagaaattga tggaagaaca atatgtattc ccagaagaag atcttgctga
    10081 agatatcgca aaagtaagtc gaagaattga aaattcatta gccaatcttg aaaaaacaga
    10141 agttgaaacg gtcgaatttg aaaaccgtga aacagctgat ttgattgatt cgttatatga
    10201 tatcttagaa cgggaaatgg aagctcagag atatgtaaaa actaaccaat caacgattgc
    10261 agagtatatc aaacatacaa caaagaataa ccgtcaatta ttgattgagc tggatcacac
    10321 atctcaaagc tatacattga accacaatga aattggccgt gtacgaggtt tccaaaccga
    10381 agtggaagaa atggaacgtc aaaatgaaca gatgattcca cagatccgtc aacacgaaat
    10441 tccttattca gaagtgcgca cgttctataa aacagtcttc aaagtcttag aagatatcga
    10501 aaagcaacaa gtagagatcg acgactcatt acatgaattg agaaaaggcg aaaaagaagc
    10561 gcaagaaaag atcgatacat tcgaattcaa attgcgcagt ttgaaacgtt ttgtagaaaa
    10621 acaacgtttg cctggcttgc cgaatgatta cctagaattc ttttttgttg ctactgaccg
    10681 tattgaagaa ctaagtgttg tcttgaataa aattcgagta aacatggaag aggtcaatcg
    10741 tttagttgct ctatgtgaag aagatctaga attattagat aagaagacac atgatttagt
    10801 agatgcagca gcattaacgg agcaaatgct ccaatatgca aatcgttatc gtcatacaca
    10861 cgaagaagtg agagaagcaa ttgataaaag ctactattta ttcaataaag aatatcacta
    10921 tcaagaagca ttagacgaaa tcggtacagc attagagcga gtagaacctg gtgctttcaa
    10981 acgcatcgaa gatttttatt ttaatcatcc agacttagta taaagcaaaa aagttagtaa
    11041 accagcaaga gcaagacgga ttattgtctt gttcttgtct ttttttgtat atttgaaaat
    11101 tgaaacaagt gaaaatttca cctgctcttg aaagcacctt ggacaaccgt tataatagaa
    11161 aagaatttca aaaaagaggg gtttcttatg atatattttg ataacagtgc aacaacccca
    11221 atctttccgc aaagcttaga tgcatatgta aaaaccagtc agcggattat tgggaatcca
    11281 tcaagcttgc atgatttagg caatcaagct aaccggttgt tgcagcaagc aagaaagcag
    11341 atcgctgatt tgatccatgt agaaccagaa gaaatctatt ttacttcagg cggaacagaa
    11401 ggagataact gggtattaaa aggaacgatg atcgaaaaaa gagaatatgg gaatcatatg
    11461 atcatttcag gagtcgaaca tccggccgtc agcgagacag cagaacaatt aaaagaatta
    11521 ggaatcgaag taagtatcgc cccagtggat aaacgcggat ttgtacgtgt cgacgaattg
    11581 aaagaattaa taagaaaaga gacagtatta gtctctgtta tggctgtgaa taatgaagta
    11641 ggatcgattc agcccatcca ggaaatcagt gatcttttgg atgattttcc taaaattcat
    11701 ttccatgtag atgctgttca ggcgattgga aaagtaccat tctcgcaatg gttgacagaa
    11761 agagttgatt ttgcaacatt ttcagctcat aaattccatg gcccacgggg aactggtttc
    11821 atttattgga aaaagggtcg tcgtttagca ccattactga caggtggagg gcaagaaaga
    11881 aatcagcgaa gtgggacaga aaatgttcca ggtattgtgg ctatggttaa agctttacgt
    11941 ttatcattag agataaagga acaaaaacct gagcagacac aacgcttaaa agtagctcta
    12001 atcaatgcgt tgaagacgta tgagaaagtg acgatttttt cagaaggaac tgactatgca
    12061 ccgcatattt tatgttttgc tctaaaagga attcgcggcg aagttctcgt ccatgcctta
    12121 gaagaaaaac aaatatttgt ttctactact agtgcctgct cctcacgtaa acatatggca
    12181 agcagtacat tgcacgcaat gcatgtacca aatgatctgg ctacatctgc tgttcgaatc
    12241 agcttagatg aaaacaattc gcttgcagaa gtcgagcaat ttatgattat tttcaagcag
    12301 ctttataaga aattttctgc aatcaattaa aagaggagtg ttcttgtgaa atacagtgaa
    12361 attatggtcc gttatgggga actttcgaca aaaggaaaga atcgaaaaag ctttatcatg
    12421 caactagcac aaaatgtcag acaagctttg aaagactttc cagaaatcaa aatccatgct
    12481 gatcgggacc ggatgcatct tttattgaat ggcgcagacg ggcagctagt tattccaaaa
    12541 ctagcaaaaa tatttgggat ccaaaatttc tctccaagta ttcgtgtaga aaaagatgtc
    12601 gaagttttga aacaagctgt tcaagacatc atgaaagaaa tttatactgg gaaagaaaca
    12661 tttaaaatta tcgctaaaag aagcgatcac caatttgaat tgacaagtaa tgaattgaat
    12721 caaacattag gtaatgctgt ttttgatatt ttcccgcata tccaagttca aatgcgtcaa
    12781 ccagatattc cattacgtgt agagattcgg cgtgatggcg cttatctatc gtatgaaacg
    12841 atcaagggag ctggaggatt gcccgtagga acaagcggaa aaggaatgct tatgctttct
    12901 ggggggattg attctcctgt agcagggtac tttgccatga agcggggagt ggaaattgaa
    12961 gctgttcatt ttgctagtcc gccgtataca agtgaacaag cactgcaaaa agcaaaagat
    13021 ctaacagcca aactagcacc ttatgtggga acgatccatt ttatcgaagt gccatttacc
    13081 gagattcaag aagaaatcaa aaagtcagtg ccacaaggat attggatgac aattactcgt
    13141 cgaatgatgt tgcgtttgac cgatgaaatt cgccgtattc gtcatggttt agtcattttg
    13201 aatggtgaat cattaggtca agtggcttca caaactttgc aaagtatggt ggctatcaat
    13261 gaagtaacga atacgccaat cattcggcct gtagcgacaa tggataaact tgaaatcatt
    13321 gaagtagcag aacagatcga tacatttaat ctttctatcc agccttttga agattgctgt
    13381 acgatttttg ctcctccaca gccaaaaaca cgccctcaac tggaaaaggt ccatcaatat
    13441 gaagagcgtt tagcaataga tgaaatgatc caacgagcac tagctggctt gaagatggaa
    13501 gagatacaag cagaatcgtc taatgaaaaa actgaagaat tttcagaatt gctataagag
    13561 gttatgaaaa tagtgttttg accagagtat tagagaaaca aaacgaaaaa atagctccat
    13621 gtattttacc gtttttgaac taatgtcgaa gattagctga ttgaatacca tttatcaaga
    13681 agttatggaa aagccggttc ttttttacta actgaaaaat aaaattttat ttagagatca
    13741 agctacagtt gataaatgat ataaaaaaga gaatttccca tgaaatagcg aggttgtgac
    13801 agaagtgggc agcttcaaga aataagaagg aatttacgaa aattgctttt caaatttttg
    13861 tgaaatttcg gcttattttt cgaagaagtt acttctggaa caccgtgtat cagaggttgc
    13921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
    13981 tacgtttggt tgagcttatt accgcagatg caagcttttg aacaccgttt tatttgtctc
    14041 acaccctttt ccttcctact tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat
    14101 atgtgaaatt attaacaagg agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag
    14161 caactgcgaa aagattacct ttatatttac gctacttgaa gatgctggat gactcaggta
    14221 taagtagaat caaatcaaat gagttcagcg aaatcaccca aattccttct gcaacgatcc
    14281 gcagagactt ctcgcaatta ggcgagctag gcagaagcgg atatggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtaa taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg ta
//
LOCUS       DAIGTA010000050        21244 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.051, whole genome shotgun sequence.
ACCESSION   DAIGTA010000050 DAIGTA010000000
VERSION     DAIGTA010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.051"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(135..512)
                     /locus_tag="NOB43_002000"
     CDS             complement(135..512)
                     /locus_tag="NOB43_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982847.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            768..1496
                     /locus_tag="NOB43_002001"
     CDS             768..1496
                     /locus_tag="NOB43_002001"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCI0982848.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1496..1750
                     /gene="purS"
                     /locus_tag="NOB43_002002"
     CDS             1496..1750
                     /gene="purS"
                     /locus_tag="NOB43_002002"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HCI0982849.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1752..2423
                     /gene="purQ"
                     /locus_tag="NOB43_002003"
     CDS             1752..2423
                     /gene="purQ"
                     /locus_tag="NOB43_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HCI0982850.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2424..4646
                     /gene="purL"
                     /locus_tag="NOB43_002004"
     CDS             2424..4646
                     /gene="purL"
                     /locus_tag="NOB43_002004"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HCI0982851.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4631..6070
                     /locus_tag="NOB43_002005"
     CDS             4631..6070
                     /locus_tag="NOB43_002005"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCI0982852.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6093..7145
                     /locus_tag="NOB43_002006"
     CDS             6093..7145
                     /locus_tag="NOB43_002006"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCI0982853.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7142..7720
                     /gene="purN"
                     /locus_tag="NOB43_002007"
     CDS             7142..7720
                     /gene="purN"
                     /locus_tag="NOB43_002007"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCI0982854.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7717..9252
                     /gene="purH"
                     /locus_tag="NOB43_002008"
     CDS             7717..9252
                     /gene="purH"
                     /locus_tag="NOB43_002008"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCI0982855.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9268..10542
                     /gene="purD"
                     /locus_tag="NOB43_002009"
     CDS             9268..10542
                     /gene="purD"
                     /locus_tag="NOB43_002009"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCI0982856.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10664..11578
                     /locus_tag="NOB43_002010"
     CDS             10664..11578
                     /locus_tag="NOB43_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0982857.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11711..13276)
                     /locus_tag="NOB43_002011"
     CDS             complement(11711..13276)
                     /locus_tag="NOB43_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0982858.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13269..14720)
                     /locus_tag="NOB43_002012"
     CDS             complement(13269..14720)
                     /locus_tag="NOB43_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0982859.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14734..15750)
                     /locus_tag="NOB43_002013"
     CDS             complement(14734..15750)
                     /locus_tag="NOB43_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0982860.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15970..17058
                     /locus_tag="NOB43_002014"
     CDS             15970..17058
                     /locus_tag="NOB43_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HCI0982861.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17112..18638
                     /locus_tag="NOB43_002015"
     CDS             17112..18638
                     /locus_tag="NOB43_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCI0982862.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18640..19845
                     /locus_tag="NOB43_002016"
     CDS             18640..19845
                     /locus_tag="NOB43_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0982863.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20102..21079
                     /gene="guaC"
                     /locus_tag="NOB43_002017"
     CDS             20102..21079
                     /gene="guaC"
                     /locus_tag="NOB43_002017"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCI0982864.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT         6812 a         3595 c         4822 g         6015 t
ORIGIN      
        1 aaccaaaaaa gaagcagatc cgttagcggt tctgcttctt ttagtttatt atattttctt
       61 atcaataata ggaacctgat tttaaaagcg gctacctctt taccgtgcct ctttacatac
      121 aaaaaataga ggaattaagc gtaaatggct tggctattat aactaaaatg ctggttatgg
      181 agatgttgca gcaagttttc gagaaaagcg tattccatct cttgtccatt gaataagatc
      241 tggatacgat aatgattttt gaaacgcttc tgttcatgaa tctgactgat tgaaagttcg
      301 cctttgtgtt ctgtctgata aagaaaagtc cttttacggc attcagcaca gcgcttggtt
      361 gctcggcgga tttttcggaa tgtataaaaa ctagtatctt tattgcataa ataaacgtct
      421 ttgatcgaca gcaaatcatt atatagacag gaacgttctt cagctgttaa ttctgataaa
      481 aaaagctgac cttgttttat tgcatcttcc atcggcaagt gcctcctcga acccattatc
      541 caaattttta gttaattcta atataccatc attaagtata aatgtaaacg cttgttgatg
      601 gtataagatt ttcgtttctg ataaaacacg aacattaaaa gaatctaatg ccttaaatgt
      661 acatattttt gttgatttat aaaaagatga ttgctaaaat ttaaagtgaa aaaacgaaca
      721 aaaaacgatg tatttgcttt taatgtaaat aaaaaggaga gacgtacatg gagaagaaag
      781 aacttttgta tgaaggaaaa gccaaaaaaa tatatcttac ttctgatgag aacttgattt
      841 ggatagaata tttagatcaa gcaactgcgt tgaatggcgc gaggaaagac cagataagtg
      901 gaaaaggaga attgaataat caaatcacaa gtgcaatttt ccgttatctg actcaaagag
      961 gaataaaaaa tcattttatt gaacaattgt ctaaaaccga acaattagca aaaaaagtac
     1021 aaattatccc tctggaagtg gttatccgaa atattgcagc aggaagtttc tcaaaacgtc
     1081 taggtgttcc cgaaggtaaa gaattcatca aaccaatcat tgaattctac tataaggatg
     1141 accagttgga tgatccattt atcaatgaag agcatatcta tttcttacaa cttgcaaagc
     1201 cggaagaaat cagtgagctg aaagcccaag cgttggctat taatgaaatt ttgaccgaat
     1261 tatttgctaa ggtcggtttg gttttagtag atttcaagct agaatttggc cggtcgaatg
     1321 gacaaatttt gcttgcggat gaagtaacac cggatacttg ccgattatgg gatgaacgta
     1381 cgaatgaaca tatggacaaa gacgtttacc gcagagatct aggtgatttg atcccagtct
     1441 atcaagaagt atataaccgt ctatcggaac taactgaaga aaaggagcga gtatgatgta
     1501 tttcgtaaaa gtatatgtaa cctataaaga ttcagtgtta gatcctcaag gggaggcagt
     1561 aaaaaaagca gtccatcgta tgggatatga aacaatcgaa gatatccgaa taggaaaata
     1621 ctttgagata caacttgctg atgcagaaga accaatcgat acagtgattg aaacgatttg
     1681 tgacaagctg cttgcaaatg taaatatgga aacataccga tatgaaatca aaaaaatgga
     1741 ggaagtataa catgaaattt gcggtcatcg tttttccagg ttcaaattgt gacgcagata
     1801 tgttatgggc agttcgcgag atcatgggcg ctgatgccga atttgtacgg catgatgagt
     1861 cctctttaga aggatttgat ggggttttac tgccgggagg attctcctat ggtgactatt
     1921 tgagatgcgg tgcgattgct cggttttcta caatcatgga agaagtgatt cgttttgctg
     1981 aagaagggaa accagtattc ggtacatgca atggattcca gatattgaca gaagcaggac
     2041 ttttgccagg tgtactgaga cgaaatgagt ctttgcattt tatttgcaaa actgtaccat
     2101 tgaaagtcaa ccccaagacg gcctttactt cagagtatga agccgacgaa ataatctatc
     2161 ttccagttgc tcatggggaa ggaaattatt tctgtgacga agaaacactt caagaactaa
     2221 aaaaaaataa tcagattgcc tttacttata atgacaacat caacggcagc gtggaaaaca
     2281 ttgcagggat tacgaacaaa gcagggaatg tgttaggaat gatgcctcat ccagaacgtg
     2341 cagtagaaga cttgctagga tcagaagatg ggaaacggtt ctttgcttcc attttaaaaa
     2401 acttcggaaa ggtgaccgta tagatgaaaa cattgaaaga accgacagct gaagagatca
     2461 agaaaaaaag aatctatgcc gaatggggat tgactgatga agaatatcga atgatcgaag
     2521 aagatatctt aggaagaatg cctaattata cggaaactgg actgttttct gttatgtgga
     2581 gcgaacattg ttcctataaa aattctaaac cggttctacg caaatttcct actagtggac
     2641 ctcatgtgtt gcaaggccct ggagaaggcg caggcatcgt cgacatcggt gatggactag
     2701 cagttgtctt caaagcagaa agtcacaatc atccttcagc cgtggagcct tatgaaggag
     2761 ctgcgacagg agttggcgga atcatcagag atattttcag catgggggct cgtccaattg
     2821 cgttgctaga ttcattgagg ttcggcgaat tagataatcc aagaacgaaa tatttactag
     2881 aagaagtagt tgcaggtatc ggcggatacg gcaattgtat cggcataccg actgtaggcg
     2941 gcgaaattgc atttgatcct tgttatgaag gaaacccatt agtcaatgca atgtgcgtag
     3001 gtttgattga acacaaacat atccagaaag ggcaagccgc tggcgtcggt aattcgatca
     3061 tgtatgtagg tgcaaaaaca ggtcgcgacg gtatccacgg agcaactttt gcctcagaag
     3121 aatttaatca agaagaagaa cagcaacgtt ctgctgtaca agtaggcgat ccttttatgg
     3181 aaaagctgct gcttgaagcg tgtttggaat taatcttgca tcattcggat tctctaatag
     3241 gtatacagga tatgggagca gcaggacttg tttcatctag tgcggaaatg gcttcaaaag
     3301 ctggctcagg acttatattg acattagatg aagtcccaca aagagaaact gggatgacac
     3361 cttatgaaat gatgttatcg gaatcacaag aacggatgtt gatttgtgtt aaatcaggag
     3421 aggaagaaaa aatccaagaa ctatttcaga agtatgatct agatgcagtc actatcggta
     3481 aagtaacaga cgacgggcaa tatcggctat atcatcaagg agaagaagta gcaaatctgc
     3541 cagtcgatgc attagctgaa gatgcaccag tttatcataa agaaatgaaa gaaccagctc
     3601 gaatcgtaga atttcagcag ttagctcctt atcagccagt tatcgaagaa cctggacaag
     3661 tattgcttga tctgctgcag caaccgacga ttgcttcaaa acgttcaatc tacgaaactt
     3721 atgattcaca agtacaaacc aatacagttg tccgtccagg aagcgatgct gctgtgatga
     3781 gggttagagg gacgaataaa gcgttagcta tgaccacaga ctgcaacgcg cgctatctgt
     3841 atttggatcc aaaaatcgga ggacaaatag cagtggcaga agctgctaga aatattattg
     3901 ctagcggtgg taagcccttg gcgatcaccg actgcctgaa ctatggttct cctgataaac
     3961 cagaagtttt ttgggaatta tcgacttcag ctgacggaat tgctgctgcg tgtgaaacgt
     4021 taggaactcc tgttatttca ggaaatgtct ctttatataa tgaaacggat ggtcaagcaa
     4081 tctatccaac accaatgatt ggtatggtcg gattgattga ggatcataaa catatcacta
     4141 ctcaggaatt caaaaaatca ggggatctaa tctatatatt aggtaagacg tttgcagatt
     4201 ttgatggcag tgaattacaa aagatgcagc ttggaagaat cgaaggtgtg atccgaaact
     4261 ttgatctatc cattgaaaag agaaaccaag agttagtatt gacagccatc caaaacggat
     4321 tgattgaaag tgctcatgac tgttcagaag gtggcttggc aattgcactg gcagaatcag
     4381 ctttcaaaca tcagctaggg atatctgtac agtttgaatt gtcctctgct caattatttg
     4441 cagaaactca atcaagattt gtgttgacag tcgcaccgga aaataagaca cgattcgaag
     4501 aaatgatggg agatgctgct gttttagcag gtaaggtgac ggatgaagcg ataatcgaaa
     4561 tttcagcaac tgacggtcag atcaaaatag aaactgcagt agcaagaaag tgctgggagg
     4621 atgcaatcgt atgtcttatg aagtgaagag tttaaatgaa gaatgcggga tcttcggtgt
     4681 ttggggtcat ccagacgccg ctagtgtggc atacttcggg ctccatagtc ttcagcatcg
     4741 aggacaagaa ggtgcaggta tcgtgtccaa tgatcgagga aagcttaagg ggcatcgaga
     4801 tttggggctg ctttctgagg tattcaaaga tcaaagaaaa ttgcagcagt taacaggaga
     4861 agctgcaatc ggacatgtac gttatgcaac agcaggcaat ggaagtgtgg acaatattca
     4921 gccttttcta ttcaaatttc atgatcagtc gatcggctta gcgcataatg gtaacttgat
     4981 caatgctcgt tcccttagaa aagagttaga ggaaaatggg gcgatcttcc attctaactc
     5041 cgatacggag atattgatgc atttgatccg acgaagtgaa gaaacagatt ttttaaataa
     5101 attaaaaagt gctttgaatg aagtcaaagg tggctttgcc tatttattaa tgacagaaac
     5161 ggcaatgatt gccgctttgg acccaaatgg ttttcgtcca ttagcaatcg gacaaatgaa
     5221 aaacggagca tacgtgattg cctcggaaac ttgtgcatta gaagttattg gggcacgttt
     5281 tataagagat gtccagcctg gtgagatagt gatcatcaat gacgaaggaa tccagattga
     5341 ttgctttacg aaggacacgc agctttctat ttgttcgatg gaatatatct attttgccag
     5401 accagattca aacatcgcag ggatcaatgt gcatactgca cggaaaaata tgggacggaa
     5461 tttagcgaaa gaatcgccag taaaagcaga tatggtcgtt ggcgtaccta attcttcttt
     5521 gtcagccgca agcggttatg cggaagctag tggaatccct tatgaaatcg gattagtaaa
     5581 aaatcaatac attgcccgaa catttatcca gccaacgcct gagctaagag agcaaggtgt
     5641 tcgaatgaaa ttatctgctg tacgaggagt agtggaaggt aaaaaggtga ttatggtcga
     5701 tgattcaatt gttcggggta cgacaagcag acggatcgtc catcttttga aagaagcagg
     5761 ggcaaaagaa gtccatgtga ggattgcttc tcctcctttg aaatatccat gtttttacgg
     5821 gattgatatt caaacgcgta aagaactcat tgcggcaaat cacacgattg atgaaatcaa
     5881 agaatgtatc ggtgcagatt ctttaggttt tttaagtgaa gagggtctga tcgaatcgat
     5941 cggtctggaa aaagatgctc cgtattcagg attgtgtatg gcttatttca acggagatta
     6001 tccgacgccg ttatatgact atgaagaaaa atatcaggaa tcactaaaag aaaaagtatc
     6061 gttcttttaa aagcagacca agaagggagt atatgaattc aatggcaaat gcatacgcaa
     6121 aagctggcgt agatgtcgaa gctggatatg aagtagtaga acggatcaag aagcatgtca
     6181 aaaaaacgga acgtttaggt atgatgggcg ctataggagg attcggcggt tgttttgatt
     6241 tatcggtctt tcaattaaaa gagccagtcc ttgtctcggg gaccgatggc gtggggacga
     6301 aattagcagt ggcaatcgaa gcagacaaac acgatacaat cgggatcgac tgcgtagcga
     6361 tgtgtgtcaa tgatatctta gcacaaggcg cagagccgtt atatttctta gactacttag
     6421 caacggggaa aaatgatccg ttacgtttgg aaaatgtagt aaaaggtgta gcagatggat
     6481 gtgttcaagg aaatatggcg ctgattggcg gagaaacagc tgaaatgcct ggtatgtact
     6541 caggtaatga ttatgatcta gccggatttg ctgtagggat agctgaaaaa tctcaattat
     6601 tgacaggaga aacgatcaac ccaggagatg tgttgcttgg aatagcatct agcgggattc
     6661 attcaaatgg gtactctctt gttcgcaaaa ttttctttga gcagcagcag ttttctttat
     6721 catcaaaact gccagaattg aaaaaaacac ttggcgaaga attgcttgag ccaacgaaaa
     6781 tctatgtttc ttccttgctt ccgctgatca aagaaaagaa aataaaagga gctgcacata
     6841 tcactggtgg agggtttgta gaaaatatcc cgcgaatgtt accagaatct atggctgcac
     6901 aaatcaaact tggctcatgg ccgattcttc caatattcgg ctgtttacaa aaatatggtg
     6961 aaattcctga gatggagatg tatgaaatct tcaatatggg catcggtatg gtcctggcag
     7021 tcgaagaatc gaaagtaaaa gaaatagtac acgaaattga gcaagctggc gaaaaagttt
     7081 atgaaatcgg gaaagtgatc gccaaagaaa aacatcgtgt ggtgtttata ggagaagaac
     7141 gatgagaatc gctgtttttg cttctggaaa cggaagcaac tttcaagcgc tagccgatta
     7201 tctatcgaaa aaaggattgg aatcttcgat tgactggttg ttttgtgatc agcctgaagc
     7261 atatgttttg aaacgtgcaa ctgcgttgag tgtaccggca gattgttttt cacctaaaga
     7321 atttgattca aaaaaagagt atgaagaagc aattttgcat aaattgaaag aaaaaaagat
     7381 cgatttgatc gtattagctg gatatatgcg aatcattgga ccggtattgc tgaaaaatta
     7441 tgataaaaga atcatcaata tccatccgtc tcttttacct gccttccctg gtttgcatgg
     7501 catacgtgat gcctttgaag ctggagtaaa agaaacgggt gtcacaattc attatatcga
     7561 ccaaggtgta gatactggac caatcatccg gcaggaaaaa gtgagaattg aacaggagga
     7621 cacgttcgat tctttagaag aaaaaatcca tagagtagag catcgaatct atccagaagt
     7681 gattagtgaa attattgaaa atggaggcta tctgaaatga caagagcatt gatcagtgta
     7741 tcagataaaa ctgggattgt agcattcgcc caaggtttga ttgaacaagg agtagaaatc
     7801 atttcaacag gaggaacaaa gcatgcgttg gataaagctg ggatcaaaac gctttcgatc
     7861 gaagaagtga cagggtttcc tgaaatgatg gatggccgtg tcaaaacact tcatcctaaa
     7921 atccatggtg gtcttttagg aagacgcgat ctccctagcc atatggaggc aatggaaacg
     7981 gaaaatatcc aaccaatcga ctttgtttgt gtcaatttat atcctttcaa agaaacgatt
     8041 atgaaaccag atgtcgaaat agcagaagct attgaaaaca ttgatatcgg tggtcctagt
     8101 atgctccgta gtgcagcaaa aaaccatgaa tttgtcacct ctgttgttga tccatctgac
     8161 tatgaagaag tactttcaga attacgtcag tatgggcata cttcactttc tttcagacaa
     8221 aaactagcgg caaaagtctt tcgtcatact gcggcatatg atgcactgat cgctcaatac
     8281 ttaacggatt gggtggaaga aaaagaaccg gaaaaattga cacttacgta tgaacgaaaa
     8341 caaacgcttc gttacggtga aaatagccat caagccgctg ccttttatca gtccgctctt
     8401 ctggaaaaat attcgatcgc agcagcaaaa caactccatg ggaaagaact ttcttataat
     8461 aatatccgag atgcagatgc tgcgctacgg atcatgaagg aatatgacga gccaacggta
     8521 gtcgccttga aacacatgaa tccttgtggt attgggacag catctacgat tttagaagcg
     8581 tgggaagcag cgtatgaagc agatcctgtt tcaatctttg gtgggatcat cgttttgaat
     8641 cgagaagtag atctgccaac agcagaacag atgcataagc tgtttctaga aatcatcatt
     8701 gccccttctt atacacaaga agctttggaa ttactgcaaa aaaagaaaaa catccgatta
     8761 ctgacagtag actttgcgca ggaagaaaat caaaatcgag aagaaacggt ctcagtctta
     8821 ggtggacttc ttgtacaaga tcaagatctg gcaatagaaa atgaagaaga gtggaaagtc
     8881 gtgacaaaac gtaagccgac tccagcagaa gcaaaagcat tagcgtttgc ttggagagct
     8941 gtcaaacatg tgaaatctaa tgcgatcgta ctggcaaacg aacgtcagac agtaggaatc
     9001 ggagccgggc agatgaatcg agtcggttca gtaaaaattg cgattgaaca agcgcaagag
     9061 aaaatggaag gtgcagtttt agctagcgat gcttattttc caatggatga ttcggttgaa
     9121 tatgcagcca aacatggtat aaaagcaatc attcagccag gaggaagcat caaagaccaa
     9181 gattctattg atatggcgaa taaatacgat ctagcaatgg tctttactga tgttcggcat
     9241 tttagacatt agagaggagt cggataaatg aacattttgg tgatcggtgc aggtggtcgt
     9301 gaacatgcaa taagtaaaaa acttttagcc agtccgaagg tggatacggt gtattgtgcg
     9361 ccaggaaatc cggggatgac aaaagatggt atcaattgtg tcgctatcag tgagcgagat
     9421 cattcagcgt taatccattt tgttaagaaa gaggctattg attggagtat cgttggtcct
     9481 gaagttcctt tgttaaatgg gatcgtcgat gattttatgg cggaaggatt gaaaatcttc
     9541 ggtccgacaa aagcagcagc tctgatcgaa ggttcgaaaa gttttgctaa acaattaatg
     9601 gatacttatc aaatcccgac agctaaatcc agaagttttg aatgttacga aaaagcagca
     9661 gcgtatatca aagaaaatgg tgcgccaatc gtagtgaaag cggacggctt agcagctggg
     9721 aaaggtgtag tcgtggctac cacagtgaag gaagcgctgg atgcggcaga acaaatgttg
     9781 aaccagcatc gatttgggga tagtagcaaa aaaatcgtcg tagaagagtt tttggcagga
     9841 gaagaattct cccttttggc gtttgtccgt aataccaagg tgtatccgat ggtcatttcg
     9901 caagatcata agcgggcatt tgataacgat aaagggccaa atacaggcgg aatgggtgct
     9961 tattcaccag taccgcaaat ttcaaaaaag atgattgaaa aagctgtgga agaagtttta
    10021 aaaccagcgg ctttgggaat gaaagaacta ggacgctctt tcacgggtgt tttatatgcg
    10081 ggtttgattg ctacgaagga aggaccaaaa gtgatcgaat tcaatgcgcg tttcggtgat
    10141 cctgaaacgc aagtcgttct ttctcggttg aagagtgact ttgcgcaagt aatcgatgat
    10201 ttattagaga atcgtacagt agagttaaag tggcagcaag aaggatacaa tgtaggcgtt
    10261 gtggttgcag ctgccggtta ccccgaagaa tatgagacag gaatggttct accagatttt
    10321 ctggaagaag agctttctgt ttactatgct ggagtttcct caaataacgg caaactagtt
    10381 ggagcaggag gacgtcttta tttagtagaa gcatacggtg agacgatcaa agaagcacag
    10441 aaaaaaattt acaccgcgtt aatggataaa acgacagatg gaacatttta tcgtacagat
    10501 attggagaaa aagctgccaa tagcgaactg atcgtgaagt aaatcagctg cttccattta
    10561 taaaaaatac aacaaacata atcggaagcg ccgattttag tgaagccttt tcataaagag
    10621 tgtggtacac ttttgttgtg tatataaata aggaggagtt cagatgaaaa aaattcaatt
    10681 aggtacttct gatcagaaag cagctgcagt gatcttaggc tgtatgcgta tcaacaatgc
    10741 ggaagatcca gtaaaagtga ttgagacagc ttatgaaaac ggcattgatt tttttgacca
    10801 tgcagatatt tatggaaacg gtgaatgtga agaaatcttt gcagatgctc tagcaaaaac
    10861 atcaatcaaa cgagaagatc tttttattca aacaaaatgt ggaatcgttc caggtgtgat
    10921 gtttgatttt tctaaaaaac atatcattga atctgtagaa aaaagtttga cccgtctgaa
    10981 aatggattat gtggatgctt tacttcttca tcgtccagat acattggtag aaccagagga
    11041 agtagctgaa gcgtttgatg aattggaacg gtcaggaaaa gttcgttatt ttggcgtcag
    11101 caatcaaaaa ccaatgcaaa tcgaattgct gaaaaaatat gttcgtcaac cattagtagc
    11161 taatcagctg caatttggct tgaaacatac tggaatgatc gatcaaggga ttcatgtcaa
    11221 tatgacagat gaagcaagta tcgatcatga cggtagtgta cttgattatt cccgattgca
    11281 tgatatgacg atccaagcat ggtcaccata ccagtatgga ttttttgaag gtgtatttat
    11341 cgggaacgaa aaattccctg aattaaacca aacattagaa gaactagcag ctaaatatca
    11401 aacgacacca actggcttgg cttctgcttg gattttacgc catccagcca atatgcaagt
    11461 gatcgccggt acgatgaacg tagggcgaat caaggaaatc gctcaagctt cagaaattaa
    11521 tatgtctcgg gaagattggt acgaattgta ccgtgctgct ggaaacattt taccttaaag
    11581 attgtcataa gcaggtcaaa agggctataa attaaaaaga cagaataact tgaaagctgt
    11641 tttcagcttc gagatattct gtcttttttt attgcaaatg gaaagagtat cattgtacgg
    11701 atttcgttta ttagttattt ttgtttttaa ggaaaagctg tgtccgatat tcttttggag
    11761 aaatcccttg ttttttctta aataaataac tgaaatagtt agggtcatta taaccaattt
    11821 caaaagcaat atctgaaata cgatagtctg attgctgcaa taattttttt gctaattcga
    11881 ttctttgttc tgtcagataa tcgatgaatg tttggttaaa cgattgagaa aaaatcgtac
    11941 tgaaatgaga gggacttaat gcaacttgtt gagcgaccca agttaaggac atatctggat
    12001 cggtaaaatt ttctttgata aaatccaatg catggttcaa aattggctga tatttgttcc
    12061 ttgaaggctg tgagggcaga gcagttaaga aagaaatgaa catataaact gtcgaacggt
    12121 aaagcgagtc gtcggcgctg attgctaagc gttgactggt ggatgtgcaa tgaaccattt
    12181 cttgcgggat tttcttttct ttcaggcaga catgctggag tagcttagtc aagacaaata
    12241 aacgatataa tcgtgttcga gttggtgtgc cttgtggttt cgtcaagtgt tcgatgtact
    12301 tagatacttc gtttttcgat aatgaagaca aatcaagtga gaggtcaaag taaaagacag
    12361 aatcaactgg aagtttcgct tcttgaatca aatcctcata gctgataatt tgttctttaa
    12421 gggaactggc ggtttcaagt atcatctgcg tgatctcaaa agatgcaggt aattcgctga
    12481 ttctttctgc gacaggacca atggcgacag aaaaattatt tttttgtccc ttttctaatt
    12541 catggaccaa cgtttgggct acctgataac tggtctcgat cacattttct tcaagagaat
    12601 caactattaa aaatttgatg aatcgagagg aaacagcaga gaagatcact tgttgattct
    12661 ccctaaataa aaacttcaaa taatcactga gatgagcgta atcttcaaag tctgtactga
    12721 cttggtttgc tgctaataat acggtcattt ttttccctgc taaagagcga ttgaaagatt
    12781 cagcaagttt caatgtttca ctgatcgtaa gtgagccttt gaacaaaccg ttcaagaaat
    12841 gatttttttt caattcgaaa acaagatcag aagaagtgtg cgtttctttt tgctgcaaat
    12901 ctaaagcagt tactgctttt tctattgctt gtttcaattc gctactttta atcggtttaa
    12961 gcagataatc atctgcctgt acctggattg ctcctttcat ataatcgaaa tcgtcgaatc
    13021 cactaataaa tatgagacga gtccaaggaa gtagtttcct tgcttctttt gaaaaagtca
    13081 acccgtccat gaaaggcatt tggatatcag tcagaatgat gtcgggctgt aagtcgataa
    13141 ttgaagacag tgccatctca ccatctccag cttcgccgac ataagtgatt ggataataag
    13201 aaccaaggac agttatttgt tcccgcaagt tattgcgaat gaggtattcg tcttcgatga
    13261 taaaaacttt atacatgttt gtttcctcca attgttttgg gagatagagg gatcatcagt
    13321 gtgacagttg ttccttctcg gtatttgctg tcaatcgtga taggtttttg atcatttccg
    13381 taataaagaa ggagacgctt gtttacgttg taaagtccgt agccgatact gaaatctgaa
    13441 tcgatccctt tggctaactc tttacgtatt tctgccagtt tttctgcagg gatgccaatc
    13501 ccgttgtcta taactttgaa ttggatcatc tcatcaattt tgcatgtggt aatacgaata
    13561 aatcctttgt gacggacgta cttcgttcca tggtatacag cattttcaat caatggctgc
    13621 aagatcattt ttaaaataga aacaggaaaa agtgtttctg gtatatcgat cttatagtca
    13681 agcatatggc cgtatcttat ttttaagatg actagataat cattgatatg gctaatttct
    13741 ttttcaagag gaatccagtc ttgtcctttg cttaaagacg tacgaaaaaa gccggaaagt
    13801 gcatgggtca tagtcagagc ttcttcaaag cagtcttgtt cgatcaaaga aataatggca
    13861 tccaaactgt tataaataaa atggggagta atctgagctt gcaatacacg aacttcactt
    13921 tgtgctaaat ggtattgttt caaagcgttc tcccgtaaag actggtttag atcttccgcc
    13981 attttattca tgctagcggt aagtgtttgt aattccagtg tttccggcag ggttaaacga
    14041 aagccaaggt tccctgaaga aagttgttct gacatctcga tcagctgatt gatcggttct
    14101 tggacctttc tctctaaaaa gcgacgattc tttttcgcat agaaaaaaat ggtactaaga
    14161 actccaagtt ccactattgt taatagaatg agcgagcgga caagtgtcgt attttttttg
    14221 cttgctaagt cgatctccac acgaacaaaa tcttgtaaga tatctgacag cagttgagtg
    14281 acagaatcta cctgattgat gatctcttca ttggtatcca taaaatcttt tgccaagata
    14341 ttattgatca gctcgttttg ataatcttcc agtgtatcga tcgtacgtag cgatacatct
    14401 aacgtactaa tttctttaag tgtatttgta ttatttttga tctctcgaat atcattccta
    14461 agttcttcta ggatattttc ctcattgaac tcatctacgg ttacttggcc agaaatcaag
    14521 tcccacatac tttccaaaac tttttgatca accttcaaag caattgcatc tgctttttgg
    14581 atatttgcga tcgtctgttg ataaatcaaa agctgttgcg aatataacag tatgctcagt
    14641 agcaaaggga taacagcaaa tagaagcatg gctttgtttg cttgggcaaa aatctgtttt
    14701 atgcttaaat tttttgtcat gatacttctc cagtcaataa tttctggttg ggatgttagc
    14761 tatattctgc tgggaaaaga cagtctcgga aataaaaata tctttaggta atgtttttcc
    14821 tgtttgaata tttccaaaat aacgagtaac ggtattggct acataccagc cgacatcagg
    14881 tttacactcg actacacaat tgacgattcc tgagcgtagc ttctcgatca tatcttcttg
    14941 tccatcaata gttacaatga tcaaatcttc tccaggtttg attgatgttt cttttatcgc
    15001 agctaaagca ccgtgagtca tttcatcact atggctgtat aatacatcga tttcggataa
    15061 atcatttgtt tctaaatatc gtttcatctg gtcttttcct ttcatccgaa taaaatcacc
    15121 gacaattcgg tgaacaatag tcatcggagg tttatggtcg atggttccat ctttttttag
    15181 ggttggttta cgattgattg attccaaaaa tccttcggag cgtagcttgg tcggtgtgga
    15241 gttctctgaa ccagcaagtt ctaggattct gatttcctgt ttctttgaat ttgtgaagtg
    15301 attgctgaca aataaacccg cccgatttcc ttctgctttg aaactggggc caatgtgggt
    15361 gacgaaaagc tcgggatcat tcgtttgaat atgtctgtcg acaagtatga cagggatccc
    15421 tgctcgcttt gcttctttta atacagagtc ccacccggat tcttgcaaag gagtaaaaat
    15481 gatcatatcc actttatagg caatgaacgt ccgtatatct tggatttgcc gttcctgatt
    15541 catgtagcca tttcggtaga gaacttggta atcttctttt tcaagcgcag tgataattga
    15601 ttcagtatgc tttttccgcc agctactctc cgttcctgat tgcgaaaaac caacgactag
    15661 tgggtcaggt gcttcctttg tattaggtgt acaccccatc atttggtaag cgattacaac
    15721 aagggctaaa aaaaataaaa cacgtttcac tttaaatcac tccatctgga tttgttagta
    15781 ctatcttatc agataaaagg gaaaatcaaa gtcaaaagga atcaatcgaa aaaaatccaa
    15841 gaaacttaaa aaaatccaag acaaaaaaag tacacctaaa aaatttaaag taaatcccat
    15901 aaaaaaatca atgttaacgc tttctttatt agctatactc ggtgtatcaa ttgaaatggg
    15961 ggataaaaaa tgaaaaacaa atttagaaag attgttggga ctatcgctat tttgaccgca
    16021 agcattctat taagtgcgtg tggcaattca ggatctgcag atgatagtac ggggtatgta
    16081 ggaatcgcta tgccgaccaa atcagcagaa agatggatcg ctgatgggaa caacatggtc
    16141 tcggaattag aaaaactggg ttataaaaca gatcttcaat atggagaaga taaagtagaa
    16201 aatcaagtag cacaaataga aaatatgatt acaaaagggg tagatacact tgtgattgct
    16261 tctatcgatg gttcggcttt aactgatgtg ttagctaaag caaaagaagc agatatcaag
    16321 gtgatcgcct atgatcgttt actgatgaat tcagaaaatg tcgattatta cgcgactttt
    16381 gataattttg gagtaggtgt atcgcaagca gcttatattg aagagcactt aggattgaaa
    16441 gaaggaaaag gaccattcac gattgaatta tttggtggct cgcctgacga caacaacgca
    16501 ctaatcaatt acaacggagt gatgtctgtt ttacaaccat atatggacaa cggtcagttg
    16561 gtcgtgccat ctggacagac gagtttcagt caaatcgcta cgcttcgctg ggatggttct
    16621 acggcgcaag caaggatgga taatctgtta agcgcaaatt atactgacca aacattggat
    16681 gctgttttgt cgccatatga tccaataagt ttaggaatca tttcgtcatt aaaaggcgtg
    16741 gggtatggga gtgaaagtaa acctttacct gtgattactg gacaagatgc gacagttgct
    16801 ggcgttaaat cgatcattgc cggggaacaa acacaaacga tctttaaaga cacacgtatc
    16861 ttagcaaaaa atacgattga aatgatcaaa gcaatcagtg atggagaaga ggttccggtc
    16921 aatgatactg aaacttatga taatggggtg aaaactgtcc ctacgtattt agcaaataca
    16981 gtatctgtcg ataaagataa ttatcaagca gagctgatcg acaccgatta ttataaagaa
    17041 tccgatctga aaaattaaga ggaaccaaac aaggaactaa agagatctaa gtcagagaga
    17101 ggataagaat tatggcggat tgtattttaa aaatggcaga tatcaccaaa aaattttctg
    17161 gaatccgagc gttagattgc gtgaatctga tgattgaacg tggggaaatc catgcattgt
    17221 gcggagaaaa cggagcggga aaatcaacat tgatgaatgt cttgagcggc ttgtatccat
    17281 atggctccta tgacggggaa atcttttatg atggaaagct gtgtcaattt aaagatttga
    17341 aagatagtga agaaaaaggc atcgtcatca ttcatcaaga attagcacta agtccttatc
    17401 tttcaataaa agagaatatt tttctcggaa atgaacaagc agaaagaggc gtgattgatt
    17461 gggaactgac agaaaagaaa acatatgaac tgctgaataa agtcggtttg tctatcgacc
    17521 cgaatcttct agtatcccag attggcgtag ggcaacagca actagttgaa atagctaaag
    17581 cattatcaaa atccgtccgt ctgttgattt tggatgagcc taccgctgca ttgaatgaag
    17641 aagaaagcgc gaatttgctg agattgatcc gagagttgaa agagcaaggt gtaacctcca
    17701 tcattatttc acataagctg aatgaaatcg tggatatcgc agatcgaatc accattttac
    17761 gggatggaca gacgattgag acactagaaa atgaaatgat cagcgaagag catattattc
    17821 gcggaatggt gggcagagat ttagttgatc gttatcctga aagaaaaccg gatattggag
    17881 aagtttattt taaagtagaa gactggacgg tctatcaccc tcttgatcac gagcgaatca
    17941 taaacgacca catcaacttg catttgaaaa aaggagagat tgtaggaata gctggactga
    18001 tgggagcggg cagaactgaa ttcgctatga gtctatttgg acattcttat ggaagcaaga
    18061 tatccggacg tatattaaag gaaggggcag agatatcagt taagaccgtt ccttcagcca
    18121 ttgcaaacgg actcgcttat gtctcggagg accgaaaatc tttaggactg aatctgctga
    18181 tggatattcg ggaaaacgtg acgctgagca gtttggataa aataagtcaa aaaggagtat
    18241 tagataaaga aaaagaagta actgaggcag aaaatttccg gaaaaagatg cgtataaaaa
    18301 caaactccat ccatcaaatt gtcagtagtc ttagtggtgg gaatcaacaa aaagtcgttt
    18361 tatccaagtg gctgatgaca caacccgata ttcttttttt ggatgagcca acccgtggga
    18421 tagatgttgg ggcaaaatat gagatctaca cgattatcga agaaatggca gcaaatggca
    18481 aagctgtctg tcttatctct tctgaacttc ctgaaatatt agggatgtgt gatcgaatct
    18541 atacgatgaa cgaaggacgt attacaggag aagtctcgcg agaagatgca gatcaggaag
    18601 tcttgatgaa attaatgacg aaagaagagg tgggttaagt tggaacaggc aaaaaatctt
    18661 acggataaaa aagagaaaaa actaaatttg aaaagtagag cagctgatct ttttggtcgc
    18721 tacagcatgg tgatcatttt agcgggacta cttattgcgt ttcaattgat gacggatggt
    18781 attttctggc gtccattgaa tataactaac cttgttctgc aaaatagcca tatattagta
    18841 ctagctgcag ggatgttatt agttgtgctc ttaggtcatg tggatttgtc ggtagggtca
    18901 gtgatggcgt ttgttggtgc aattgcgggc atgatgatgg tcaatcgcca aatgaacccg
    18961 tggatgacag ttatcgcatg tcttgcagta ggcgggctga tcggcgcatg gcaaggtttt
    19021 tgggtagctt atgcagggat accggcgttt atcgtgactt tagcaggatt gctgatgttt
    19081 cgtggactga cacaagttgt tctaggaggc caatctctag caccttttcc agctgttttc
    19141 caaaaaatgt ctacgggtta tttaccagac ttaagcgaag gaagcagcct tcacttcttg
    19201 acattgattt taggaatgat catcacgatc gtgttagttg ttggtcaatg gcgaacaaga
    19261 aatcgtcgga aaaatcattt atttgaagtg gaatctccaa cagctttctt ggtaaaggcg
    19321 gtatttacag cagtcgttgt actaggaata acttatatct ttgcctctta tcaagggtat
    19381 ccgattattt tgatcattct tggtttgatc gttgcagcat atgggttttt gacaaataaa
    19441 acagtagcag gtcgacagat ttatgcgacg ggcggaaatc gaaaagcggc tgaactatca
    19501 gggatcaaaa caaagcgaat cacgttctgg gtattcgtca acatgggagt catggcagct
    19561 ttagctggat tagttttagc tgctcgattg aatgcggcaa cacctcaagc aggtacatcg
    19621 atggaactgg atgcaatggc ggcagtatat tttggtggtg cttcgacttc cggcggcatt
    19681 ggaacaatca tgggtgcgat tgtcggtggc ttggtcatgg gtgtattgaa caatggcatg
    19741 tcgattttag gcgtcggggt agactggcag caggcaatca aaggattgat cttgctttta
    19801 gccgttgtgc tagacttgta taataagaaa aaacgaacaa cgtaggagaa cgccggttat
    19861 tcagaaaaaa gactgtgaca agacatttgt cacagtcttt ttttcgctaa aagcgaacat
    19921 tcattgtttc gtttgtatag actaaaaata atatatgttt ttttaccatt cgtataaatt
    19981 ctctttttgc tcttgatttt tttgcttaat tgagttaaat tacatagggc gctaaaaaaa
    20041 gccttgatta aattaataat gttcgtgttt tgctggatgt gaacatcagg aggataatgt
    20101 aatgaaagta tttgattacg aagatattca attaattcct aataaatgta tcgtaaatag
    20161 ccgttctgaa tgtgatacaa cggtcacatt aggtaaacat acattcaaaa tgccagtagt
    20221 gcctgccaac atgcagacga ttattgatga aacaatcgca gaattcttag cggaaaatgg
    20281 ttatttctat atcatgcatc ggtttgatga agcagctcga attccgttta tcaaaaaaat
    20341 gaaaaagcgt ggattgatta cctcgatcag tgttggcgtc aagaaagagg aatattcctt
    20401 tatagagaag ttggcagaag aatcgctaaa tcctgattat atcactatcg acatcgcgca
    20461 tggacatgct aactcagtta ttgatatgat tcagcatatt aaaaaatatt tgcctgaaac
    20521 ttttgtgatt gccggtaatg ttggtacacc ggaagccgtc cgtgaattgg aaaatgcggg
    20581 cgcagatgca acaaaagtcg ggattggtcc aggaaaagta tgtattacaa aaatcaagac
    20641 aggctttggg actggaggct ggcaactggc agctcttaga tggtgtgcga aagcagctcg
    20701 caagccgatc atcgctgacg gtgggatcag aacacatggc gatattgcaa aatctgtccg
    20761 ttttggtgcg acaatggtca tgattggttc attgtttgcc ggtcacgagg aatctcctgg
    20821 cgaaacaaaa gtcgaaaatg gaatcgtgta taaagaatac tttggttctg cttcagaatt
    20881 ccaaaaaggc gaaaaacgaa atgttgaagg aaagaaaatc tggatccaac acaaaggatc
    20941 tttgaaagat acactagtgg aaatgcaaca agaccttcaa tcatctattt cttatgctgg
    21001 aggaagagat ctggaagcca ttcgaaaagt tgactatgtc atcgtgaaaa attcgatttt
    21061 taatggagac acaatctaaa aaataaataa aatattagga tgttgtgaaa aagttgtcct
    21121 gcattaagta ataagaacag ccaaacaaaa atagttcttt atatgttttg tttggctgga
    21181 attattatcg cagatacaag cttttgaaca tcattattca gaataaggga ctgtgataag
    21241 attt
//
LOCUS       DAIGTA010000051        21100 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.052, whole genome shotgun sequence.
ACCESSION   DAIGTA010000051 DAIGTA010000000
VERSION     DAIGTA010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.052"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            155..1861
                     /gene="efbA"
                     /locus_tag="NOB43_002018"
     CDS             155..1861
                     /gene="efbA"
                     /locus_tag="NOB43_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HCI0982865.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2019..2921)
                     /locus_tag="NOB43_002019"
     CDS             complement(2019..2921)
                     /locus_tag="NOB43_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0982866.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2918..3610)
                     /locus_tag="NOB43_002020"
     CDS             complement(2918..3610)
                     /locus_tag="NOB43_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HCI0982867.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3653..4294)
                     /locus_tag="NOB43_002021"
     CDS             complement(3653..4294)
                     /locus_tag="NOB43_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0982868.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4332..4646)
                     /locus_tag="NOB43_002022"
     CDS             complement(4332..4646)
                     /locus_tag="NOB43_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982869.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4634..5986)
                     /locus_tag="NOB43_002023"
                     /pseudo
     CDS             complement(4634..5986)
                     /locus_tag="NOB43_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5983..6915)
                     /locus_tag="NOB43_002024"
     CDS             complement(5983..6915)
                     /locus_tag="NOB43_002024"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCI0982870.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6912..7688)
                     /locus_tag="NOB43_002025"
     CDS             complement(6912..7688)
                     /locus_tag="NOB43_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HCI0982871.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7742..10927)
                     /gene="carB"
                     /locus_tag="NOB43_002026"
     CDS             complement(7742..10927)
                     /gene="carB"
                     /locus_tag="NOB43_002026"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCI0982872.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10932..12008)
                     /gene="carA"
                     /locus_tag="NOB43_002027"
     CDS             complement(10932..12008)
                     /gene="carA"
                     /locus_tag="NOB43_002027"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCI0982873.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12013..13293)
                     /locus_tag="NOB43_002028"
     CDS             complement(12013..13293)
                     /locus_tag="NOB43_002028"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCI0982874.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13312..14238)
                     /locus_tag="NOB43_002029"
     CDS             complement(13312..14238)
                     /locus_tag="NOB43_002029"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HCI0982875.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14251..15534)
                     /locus_tag="NOB43_002030"
     CDS             complement(14251..15534)
                     /locus_tag="NOB43_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCI0982876.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15548..16087)
                     /gene="pyrR"
                     /locus_tag="NOB43_002031"
     CDS             complement(15548..16087)
                     /gene="pyrR"
                     /locus_tag="NOB43_002031"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HCI0982877.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16322..17233)
                     /locus_tag="NOB43_002032"
     CDS             complement(16322..17233)
                     /locus_tag="NOB43_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0982878.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17230..17694)
                     /locus_tag="NOB43_002033"
     CDS             complement(17230..17694)
                     /locus_tag="NOB43_002033"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCI0982879.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17699..18397)
                     /locus_tag="NOB43_002034"
     CDS             complement(17699..18397)
                     /locus_tag="NOB43_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0982880.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18384..18770)
                     /locus_tag="NOB43_002035"
     CDS             complement(18384..18770)
                     /locus_tag="NOB43_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982881.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18917..20587)
                     /locus_tag="NOB43_002036"
     CDS             complement(18917..20587)
                     /locus_tag="NOB43_002036"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HCI0982882.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20770..21003
                     /locus_tag="NOB43_002037"
     CDS             20770..21003
                     /locus_tag="NOB43_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HCI0982883.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
BASE COUNT         5901 a         4746 c         3743 g         6710 t
ORIGIN      
        1 cctaaaaatt tggatttcaa cgatagaaac actgtttttt atgtaattag tccaagattt
       61 ttctagactt ttgctttact attcggccaa attggttttt cttctttttt tcgttataat
      121 gaatatactt atgaaaagaa atgaggaatg aaccatgtcc tttgatggtg tatttaccca
      181 cgcgatggtc aacgaattgc gtgaaacgtt actatctggc cggatctcga aaatccatca
      241 gccttatgaa aatgaaatcg tgctggtgat tcgttcacgc ggcaaaaacc atcgattatt
      301 attatctgcg cacccaagtt atgctcgtgt acagattacc caaatcgatt atcagaatcc
      361 tgataatccg cctaacttcg tgatgatgct tcgaaaatat ttggatggcg ctattttaga
      421 agacatcgaa caaatcgaaa atgatcgagt gatccatttc cactttgcta aacgaaacga
      481 gttgggtgat ctacaaaata tcatattgat cgttgaatta atgggacgtc atagtacgat
      541 cgtcttagtt aatcgagaaa ctggaaaaat actggatgcg atcaaacaca ttggaagctc
      601 tcaaaacact tatcgttctt tgcttcctgg tgtagaatat gttgctccgc caaaacaaga
      661 ggtcttgaac ccatttagct ccgagaaaga aaaaatcttt cagcggcttt cccaaactga
      721 actagatcca aaagcaatcc aacgtcagtt tcagggaatc ggtttcgata tcgctcaaga
      781 gctgaccaaa agattactgg aacgtcctaa tgaaaagatg gttgtatggg acgaattttt
      841 ctcagccatc agccatcagc ctattcctac tttttacgaa acggaaaata aagatttttt
      901 cacaccgatt gcttatcagg tattgtccga acaggcatct gctgtaacag cttatccaac
      961 actcagtcaa ttattagata gctattatca cgaaaaagca gagaaagatc gggcaaaaca
     1021 acaaggcgga gaactgattc gaaaaatcga aaatgaacta aaacgaaata aaaataaatt
     1081 gaaaaaacgt gaacaaacac tcaaagaatc cgaaaacgct gagaattacc gtagaaatgg
     1141 cgaactactt actacttttc tgacacaagt accacgcggc gcaaaagaag ttgttttacc
     1201 taattattat gaagaagatc ggccaatcaa aatagcacta gatccggcat tgacaccaaa
     1261 tcaaaatgca cagaaatatt tccatcgata ccaaaagctg aagaacgctg ttaagctgat
     1321 tggcgaacaa atccaagaag ccaaagatga aatccaatat cttgaatctg tcttatctca
     1381 actggaaatt gccggcccaa tggatatcga agcaattaaa gaagaattga cttcagaagg
     1441 atacctgaaa aagaagaact taaaaaaaca aaaacgtaag aaaccatctc agcctgatca
     1501 atacttttct tctgacggaa cgctcattct tgttggtaaa aacaatcttc aaaatgacca
     1561 gctgacaatg aagacagcta aaaaaaccga ctattggctt catgcaaaaa atatacccgg
     1621 ttcgcacgtc atcattaaaa gtgacaagcc ctcagatgaa acaattacag aagctgccga
     1681 gttagctgcc tatttttcaa aataccgata ctctgcccaa gtgccggttg atcttgtaca
     1741 ggtaaagcat atccgaaaac caaatggcgc caagcctggt tatgttattt atgaaaacca
     1801 aaagacgatt atcgtgacac cagaagaaga aaaaattaca gctatgaaac aaaacaggta
     1861 atcaatgagt gtttctagaa tcatatttgc gtactttccc acaacagcaa ttagttataa
     1921 attgtttgct acaaaaagag gagttgtgac aaaattctgt cacaacccct cttttttgat
     1981 caacggtgtt caataaacag cgttctcatc tgcttttctt agctctgctg gtccagtaac
     2041 cgagtaagct ctttgataaa tctttgagcg atttcactga gcggacgttt cgccgaataa
     2101 atgatataaa attcatttag ttcgccttct gccaaaggga ttaaccgcaa gtgctcgcga
     2161 atccctccaa tcacaatacc agatcctgaa gcgtaagcat cagtttcaag aacgatattc
     2221 atcaaagtac ctcgatcact cgtataaatc actgtttctt gatcagggat ctcgataagg
     2281 tcttcataaa aatacgggaa attatttcca tcctgtgtaa aacgaacttg aggataagat
     2341 aacaattctt ctttggtgat ctctgcgtgt tcagctaatg gatgtccttg ccttaaaaaa
     2401 atatgcgttt tgaattttcc aatgctgcgg ccacttagct ctccttgttg taaatatctt
     2461 ctgataccag cttgattatg ctcattcata taaataatgc cgatctcact gtgctgctct
     2521 ttgacttctt cgatcactct cgctgttgtc gtctccatga tccgaaattg tttgatctcg
     2581 tctttgaatt cctcgagtag ctgtgcggtc aaaggaccta agaaatcata atgctgggca
     2641 gcgatcgaaa aattgtctct cttttcactc gttagatagt gagtttctaa tgtatcaagc
     2701 tggaccaata ttttctcggc acgatttaag aagtcttgcc cttcttctgt taaatatgcc
     2761 cctcgattcg ttcgagtaaa cagcgtgatc cctaactcgg tttctaattc tttgatacca
     2821 gctgaaagac ttggctggga gacaaacatt ttctttgccg cttctctgaa actaccattg
     2881 tttgctacag cgaccacgta tttcatctgc tgaatattca ttgctcaaac tcctcgaaat
     2941 aataaatttc tcttccattc aagggctgga ttggtcggtt gttcggtcga gcatactgac
     3001 catcgaaggg gagaagaaac tcttggttca gttttcctac atgatccatt acaaaccatt
     3061 ggattggccc gctggtaggc ggagttgtca atgagccaat ataatggaaa tggctttttt
     3121 gctccggaaa gaacacatcc ggatttaccc aatgctcatg tttttctaag ttccaacttt
     3181 ccccattttc ttgattatac agccaacctt cctgtaccat tagctggtac atgacaccca
     3241 caactagatt ctcttttttg ctgttcatat gaacaaaatg aaattcaata tcttcctgtt
     3301 ttccgttgat gatatgttca gaaggcaagt ggaaatgaat atctgtcaaa taatagcgtt
     3361 ctttcttgaa ctctacataa ctgagttggt caaaaggtac taaatgaatc gtgtttttga
     3421 attccttgtc agtaaaccgt tgcttttgat aatgaaagga aagcgtgtct ccttctattt
     3481 tggtttcttc ccccttggtc aaatgaatag gcgactgcaa tggaaattcc gcacctctcg
     3541 caaaccaatc acataaactc gcccaatttt ccggaccttt gtctccagaa tagccccatt
     3601 cgacatccat attctttttc aactatactt ccccctgcat ctcatatcat ttttattttt
     3661 cttctttctt tacaatcgtt gagacggttt ctaaaaacgc ctcttttcca taaaattcct
     3721 ggttcaatag ttccggaaat atctctttaa agaaatactg aacagaaggc cgatgttcaa
     3781 agcttttaat cgtagtcact gcctcaatga acatctcctt ataaactttt tccgggttat
     3841 ttttgatgat ttcatcaaaa gattcataaa gaaggtcaac cttatctgaa atggctaata
     3901 gttctccttc tacggtttca tcttttcctt cgaacaaccg acggcgataa acttcttgga
     3961 actcagctgg aatctcttgg ttgatgaatt cgtccgtcat cttttcttca actgtttgca
     4021 gcatccctct taactctttg cttgcgtatt tcaccggcgt tttgatatca ccaataaaac
     4081 gctctgtgta gtcatgattc aatgattttt catagagcag tttccaatcg atcggttgtc
     4141 cattcgcttc ttcaatgtct cctagaactt gcgcaataga tgctacacga tacgaatgtg
     4201 ctgcaactgt atgctctgta tatttaaaaa atccaggtgc ccttgtgatc gtctctaaat
     4261 tgttcaatcc taaaataaat tcattcaacc ccataaaagt tacctccctt tgagatttct
     4321 ttttccgaat atcatatcat taaataactg atattcgcaa catttccgct ctttaccatt
     4381 tttgaaacag ctcccttacc aaaaaataga gaaaatctat atataataga aaaaagagaa
     4441 gagattattc tcttctttct gctaaccagt cttagaaaaa tgaattttaa aaaaatcaaa
     4501 aactgatcac gatagaagtt tcttttcata cctgatgaaa agatgcttct cgcaatcagt
     4561 ttttggattt ttgctattcc aattgatgat tctggagaca caaatcggat ttctctatct
     4621 tcatcaagcg cgcttaaatc tgccaatttt caggatcttt tttccattct tttagcagag
     4681 ttaattcttg ctcatcgata taacgatctt ctaaagctgc ttcaatcaat acagaataat
     4741 tggtcaacgt cataagaggg atttcggctt tttcgaaatt tgcttttcct tttggcaact
     4801 catacgtaaa gatagccgca acaccaagga tatccgcacc ttctcttttt gctgcttcag
     4861 ctgcttccaa gacacttccg cctgtagaaa tcaaatcctc gatcacaacc atcttctgac
     4921 cttcaaatat acgtccttcg atttggttac ctttcccatg atctttcgcc ttacttcgaa
     4981 tatagaccat tggcaaatcc agtatttccg ctacccatgc ggcatgaggg attcctgctg
     5041 ttgcagttcc agcaatcact tgtacttcag ggtaagcttc tttgattttg cttgctaatc
     5101 cttttgcgat ctcttttcgg acttttggat agctcatcgt gattcggtta tcacagtaaa
     5161 ttgggctttt gattccactt gcccatgtaa aaggattact tggatttaaa aatactgctt
     5221 caatttctaa taagtctttt gcgatacttt gttcaacatt cattttaggt tagctccatt
     5281 ctgtttgaat cgtttgatat gctttataag gattagttga ctgagtgatt ggtcgaccta
     5341 taacgataaa agttgagccg atcttttttg cctgagaagg tgtgactact cttgtctgat
     5401 ctcctgcgac tgttccttct ggtcttatac ccggagttaa gcaaacaaat tcgtctcctg
     5461 ccatttcttt gatcgcttct acttcccaag cagaagaaac cacaccatct aatcctgctt
     5521 ttttggcaca gctagcataa tggatcacac ttttttctaa agaaacttcg attagttgat
     5581 cggcatgcat ttcttcttca cttgtagaag taagctgagt gatagctaga agtagcggac
     5641 gttttccacc ttctggagtc ccctcttcta atcctcgcat tgccgcctcc atcatacgaa
     5701 taccgccagc ggcatgaaca caggtgagat caacaccaag ctttgccaat ccccgcattg
     5761 ctttttcgac cgtattcgga atatcgtgaa gtttcagatc taaaaataca ttatgaccag
     5821 cctcttttag ataacgtacg atttcaggtc cttcttggta gaacaattcc attccgattt
     5881 tcacaaacaa tttttcttct ttcgggaaaa atcgaagaaa gtcttctacc tcttgcctag
     5941 ttgaaaaatc taatgcaata attggtcgtt ggtctagttg attcatcgtt cacgttcctc
     6001 tctcacttct ttgattaatc tttccagcga ttcgatgcct agttcgctca ttcgcacagg
     6061 gagctcttta attagtttag gacagatata cggatcggtg aaattcgcgg tccctatagc
     6121 tacagcactt gctccagcca taaacatctc aagaacatca tccactgtct gcacgccgcc
     6181 catcccaatg attggaaggc tggatatact tgctacttgg tgaatcaaac gaatagcgac
     6241 aggcttgatt gctggtccgg agagtccacc tgtttgattg gctaaaatcg gttttcttgt
     6301 cttaaggtca atccgcatac caagaagagt attgatcatc gtaaacccat ctgcccctcc
     6361 agcttcgatt gcctgagcga ttggaacgat gtctgttaca tttggggaca atttgacata
     6421 gacaggaaca gaagaaactt tctttactgc ttgtgttaat tgaaaagcaa catcagaatc
     6481 tgttccaaaa gcaattccgc catgtttgac atttgggcaa gaaatgttca gctcgattgc
     6541 tttcacattt ggtgcttcgc caattttgct acaaacttct acatagtctt cttcacaagc
     6601 accagcaaca tttgcgatga tgggtaactc attgtactcc tctaattctg gaagaagttt
     6661 atgcataaca acgtctagac caggattttg caaaccaatt gcattcaaca tgccagatgg
     6721 tgtttccgcc actcttggcg tgggattgcc aaagcgggca tttggagtcg ttgccttgac
     6781 catgatcgat ccaagctgat tcaaatcata gtattttccg tattctttgc caaaaccgaa
     6841 acagccgctt gccggcatga taggattttt taattctagg ccaggaagtt tgaccgctaa
     6901 aggattctca ttcatataat tacctctcct attttaaaaa tcggtccttc gtcacaaact
     6961 ttcacacttt ttgttcctgt ttcatcttcc ggcgtatgac aaacgcaagc atagcaagcc
     7021 cctatcccac atgccatgcg ggattctaat gataactgga cattttgatg cgaagaaaac
     7081 agctgttcca ctgtcttcaa taacccgttt gaaccacatg caaaaacagc tgtaggttcc
     7141 gtcttcgttc ctaacaataa attaccgaca tttccgtgca taccgtatgt tccatcgtca
     7201 gtagcgattc ttgtttctcc tagacgatta aattcttttt cataataaac gacttcatgt
     7261 gtggcaaaac ctaaaaaatg cgttggctta attccttttt cgactaactg ttttgataac
     7321 tcatatagag gagggacacc gattcctcca ccgattataa atacttcgtc tcctgtatga
     7381 agattggaca aatcaaaacc attgcctaaa ggacccatga catctaaatg gtctccggca
     7441 gaaagagtag agaagactct agtcccctca ccttccaccc gataaatgat acggcaagta
     7501 tttgtttcgt ggtcgatatg attcaagcta atcggtcggc gtaatagcaa gtctgcacgc
     7561 ggcacgagaa tatgcaagaa ctgtcctggt tgctgcattt cttttactag atcacctttc
     7621 aatgtcattt caaaaatctt tggtgccagc tgtttttgct gaacgatttc catcatttct
     7681 tgtttcatct gtcccctcct gcaacggttt ttcgtctttt tgtcttaaca tgtgctcgcc
     7741 gttaaatagg gttagttgaa aaagcacggg attccatcac tcgaacgatc gcatctgctg
     7801 tgtctaaaga agtaaacaat ggaataccat gttcaactgc ttctcttcgg atgatgaaac
     7861 cgtctttaga agcatttccc cgatctttat caatcgtatt gacaaccact tgtgttttac
     7921 catctcttat taagtcgact acattttttt ctgctgcttc ctcagaaatt ttcgctactg
     7981 tttcaacgac cagaccattt ttttcgaaat aagcagctgt atgtttcgtt cctatcagac
     8041 tatagccaat ttctgtaaaa cgtttagcta attctagtgc ttcttctttt gtttcgtccg
     8101 caatcgtaaa taatacggct ccatattcag gcaagtgtaa tccagaagct tcgaatgcct
     8161 tgtacaaagc tttgtctaat tgtctgtcag atcccattac ttctccagtc gatttcattt
     8221 caggccctaa gtaagtatca actttctgca atttcgtaaa agaaaagaca ggtgctttaa
     8281 catgaacttc ttttgtttct ggataaagtc cgttttcata accaagtgtc tttagtttct
     8341 ctcccaaaat agctttcgtc gcaatttgtg ccattggaat tcctgtcacc ttacttaaga
     8401 atggaacagt ccgacttgct cgaggattga cttcgatcac ataaacctca ttttcatgga
     8461 tgacaaactg gatattcatc atcccgacac aattcaaacc taatgctaag cggatcgtgt
     8521 aatcttcgat cgttttcttg atcgattcag ataatgtttg aggtggatac acagccattg
     8581 aatcccctga atggacacca gcacgctcaa tatgctccat gatccctggg atgagtactg
     8641 tttcaccgtc acaaatcgca tccacttcgc attcaccacc aagcaagtaa cggtccacta
     8701 gtactggatg ttctggagat gctttcacag catgttccat gtaatcttct aaatctcgct
     8761 ggttttcaac gatttccatc gcacgtccgc ctaatacata gcttggacga acaagaactg
     8821 gataaccaat tctcgaagcg ataaccacgg cttcttcttt acttgtagca gtatccccta
     8881 aaggttgagg aatatccaac tctttcagcg cttgctcgaa taaatcacga ttttccgcac
     8941 gatccaagtc ttcgatcgtt gtccctaaga tttttacacc agcagcagtc aaaggttcgg
     9001 ctaagttgat tgctgtctga ccaccaaatt gaacgattac tcctatcggc tgttctagct
     9061 cgatcacatt catcacatct tcgaaggtca atggctcaaa atataattta tccgaaatag
     9121 aaaagtcagt cgaaactgtt tcaggattgc tgttcatgat gattgcttcg tatcctgcct
     9181 gctggattgc tttgacagaa tgcacagtcg catagtcaaa ttcaacccct tgtccgatac
     9241 ggataggacc agatcccagt actagaattg agggcttttc tgatcgtgaa ctttcatttt
     9301 catattcata ggaactataa aaataaggtg tttttgattc gaattccgct gcacaagtgt
     9361 caaccatctt atatacagga atcaaatcat tttcttttct catctggcga acggcttctt
     9421 cgtttatttc ccacagctcc gccacttttt tgtctgtaaa accgttttgt ttcgctgttt
     9481 tcaatatctt gtcatccaac ggctgctgtt tcaactgctg ttcgatttct acgatatgca
     9541 acagtttatc taaaaagaat aaatcgattt ttgtcaaatc cgctaattct tctatggtgt
     9601 accctcttct aatagcttca gctacataaa acaggcgatc atcttgtgct cgaaccactt
     9661 tttggattag gtcatcgtcc gtgatgtctg ccaactcagg aagttcgata tggtgtgtac
     9721 cgatttctaa agaacgcaca gctttcaata aagactcttc gatattccga ccgatagcca
     9781 tcacttcacc agttgctttc atctgcgtgc ctaaaagccg ttctccgttt tcaaacttat
     9841 caaacggcca gcgaggaatt ttagctacaa cataatctaa tgcaggttca aattctgcaa
     9901 aagtcgttcc tgtaacagga tttttcattt cgtctaatgt taatccaagc gctattttag
     9961 cagctagctt agcgatcgga tagccagtcg ccttacttgc taacgcagat gaacgagaaa
    10021 cacgcggatt gacttcaatc acataataat taaaactatg tggatcaaga gcgagttgga
    10081 cattacagcc tccctcgatc ttaagtgctc gaataatcga aagagaagca tcacgaagca
    10141 tttgatattc atggtcagac aatgtttgac taggggcaaa tacgatagaa tcacctgtat
    10201 ggatacccac cgggtcaaaa ttttccatat tgcagacaac gattgcatta tcagccgaat
    10261 ctctcatcac ttcatattca atttctttaa aacctgcaat acttcgttca atcaaacatt
    10321 gggtagcggg ggaaagactt aatccatttt ctgatacgat acgtaattct tcttcatttt
    10381 cacacatacc tccaccagtt ccgcctaaag taaaggctgg acgaacgatg acaggatagc
    10441 cgattttatt tgcaaaatct acagcttctt ctactgtatt gacgatttca gactcgggga
    10501 ttggctgatt caattctttc atcaactgtt tgaatagatc acgatcttct gcttgatcga
    10561 tcgcagaaag ctttgttcct agaagttcta tgttcaattc ttctaaaata cctgatgctg
    10621 ccagctccat tgccatattg aggcctgtct gtccgcctaa agttggaagg agagcatctg
    10681 gacgctcttt tcgaagaatc cttgatacaa attcaagtgt gatcggttcg atatatactt
    10741 gatctgccac ttctttatcc gtcatgatcg tcgcaggatt agaatttact aaaaccactt
    10801 catatccttc ttcttttaag gcaaggcagg cttgtgttcc tgcgtagtca aattctgcgg
    10861 cttgaccaat gatgatcgga ccagatccaa tcaccataat tttcttgata tctgtacgtt
    10921 tcggcatctg tttactgctc ctttcctgcg tccatcattt ccataaattc atcaaataaa
    10981 tgtagtgcat catgcggacc aggggcagca tctggatgaa actgcacact gaaagcggga
    11041 taatctctgt gtttgactcc ttctactgtt ccgtcattta cttctacatg agttacgatg
    11101 agtttttctg gatcaatcgt ggcttcatcg actgcatagc catgattttg agaagtaaaa
    11161 tcaattcttc cggtcgctac ttctcgtacc gggtgattta atcctcgatg tccgaatttc
    11221 attttatagg tatctgcacc gttggctaaa gcaaataact ggtgaccgag acaaatacca
    11281 aaaatcggta cttttccttg gatttttttg atcatttcga ttgcttctgg cacatctttt
    11341 ggatcaccag gtccattcgt cagcatgact ccgtctggtg atagcgctaa aatcgtctcg
    11401 gcatctgtgt tatagggaag tactgtgagg ttacagtttc ttttactcaa ttctcgtaaa
    11461 atactatgtt tcaagccgaa gtcaatgaca atgactttcc gacctgttcc tggacttgga
    11521 taaggtttgt tagttgagac ttgctgcact tgattggttg ctagaacggt tgctttcagc
    11581 tgatcaaatg catgttcgaa ggaatctcca gcatcaacga tactagcttt catcgttccg
    11641 acttcacgga ttttgcgagt aagggcgcgc gtatcgatac ctgatattcc aggaattcct
    11701 ttttgtttca aaaatgaatc tagcgtcatt tggtttcgcc agtttgaagc tacacgtgca
    11761 tgttctttta ctactactcc tttgcatgtt ggagaaatcg attcataatc atctctattt
    11821 accccataat tacccaccat aggataggta aatgtaatga tttgaccgtt aaaactttga
    11881 tcagtgatag tttcttgata accagtcata cttgttgtaa aaacgatttc tccgaagaca
    11941 ctagcatctg caccaaaagc ctttccttcg aaaactgttc catcttctaa tataagcaaa
    12001 cgttccatac ttttattctc ccttctgcca cacaagtttt ccgttgacaa aagtcatttg
    12061 tgtttcgcct tttactttcc agccgataaa aggtgtattc tccccttttg ataaaaagtc
    12121 ttctttatcg atcgtgcaag tttgtgtaat atcaaaaact gctacatcag cgggggcacc
    12181 aaccgttagc gttcctgcat tcaaaccaaa aatctcagcc ggtttaactg ccaaccaatt
    12241 gatcacttgt tccaacgtga atcgaccagt ttctacaaaa tgagtataga tcagttgaaa
    12301 cgctgtttcg cttcctacga taccaaatgg tgatttcatg aaactttggc ttttttcttc
    12361 taatccatgg ggggcatggt ctgtagcgat gcaatcgatc gtaccgtcaa gcaagccttc
    12421 gatcaaagct tctctgtcct cccgtcctct tagcggcggg ttcattttcc aaaagccgaa
    12481 atcttcggga atatcttcgt cgatcaaaat aagatgatgg ggtgaaactt ctgctgttac
    12541 gtggattcct gctttttttg cgtctctgat tacacggaca ctttctttag tagaaacatg
    12601 gcaaacatgg taatgaacac cagttgcttc agctagcaac agatctctag caatttgaga
    12661 agactcggtt acgcttaaga tcccgggaag accaagttct tctgccttct tgccagcgtg
    12721 cataacgccg ccaaataata aagattcatc ttctgtatgg gctactaggg ctttattgtt
    12781 ttttgcagct tctttcatag ccagatacat cgtcccagct gtttggacac ctacaccgtc
    12841 atttgtgaaa gcaaaagcac cttcttcaat cagtgcttct tgatcaacta atttctcact
    12901 tcgcagattt tctgtgattg gcgcatactg caataccttc acaactgcat cttttctaat
    12961 gatgtcatat acttgtctca gcttttctgc cgtatcaggt acaggattta aattcggcat
    13021 cgcgcataca gtagtgaaac cgccacgagc agctgagcga gtcccagctt cgatcgtctc
    13081 cttgtatgta aatcctggct ctctcaaatg aacatggacg tccactaaac caggtgtgat
    13141 caattgtccc tttgcatcaa acacttcatc aaattcggct tctgagaatc ctgtaccgat
    13201 tgctttgatt cgcccatctt ctatccaaat ttctgctggt gtcgtcatat tttttcgtgt
    13261 attgatctga ccgtttttaa tgagtgtttt cattttttca tcctcctata attacgcttt
    13321 tccatttagc actgcttcta agattgccat tctgacgaat actccattgc tcatttgctg
    13381 aacgatccgc gactgtaatc cttccactaa tgaatcagct aattctacat cacggttaac
    13441 tggtgctggg tgcataatga ttgcatgttt ttgcaacttc ttcgcacgct caactgttaa
    13501 cccatgttcc tgatggtagc cttcttttga gaaactttct tttccatcat ggcgttcgtg
    13561 ttgcacccga agcatcatca tgacatcaac ttgatctagt agttcatcca atggcatata
    13621 atgtccgtac acttcgaatt catcgtcgta ccattctcta ggacctgaga agaatacttg
    13681 tgcgcctaga cgttttaaca tctgcatatt ggatttagct acgcgagagt gagtgatatc
    13741 acctacgatg gcaactttca gaccttcaaa atgaccaaat tcttcataaa tggtcatcaa
    13801 atcaagcaag cattgggttg gatgctgtcc gcttccgtct cctccattga taatcgaaca
    13861 ctggattgtt ttactttgta tcagttcgtc ataatagttc tcatcaccat gacggataac
    13921 cgctacgtct acgcctaatg ctgacatcgt cagtactgta tcgtatagtg tttccccttt
    13981 ttggacagag cttgtgcttg cttcaaattc aatcacttct agccctagtt ttttctccgc
    14041 tacatcgaag cttttatgtg tgcgagtact attttcgaaa aagaggtttg tagcaaagta
    14101 ctggcgcttt tgcggagtcc aattagcacc ttgcttgaat tcctgccctc tgcggatcaa
    14161 gcccataact tcttgatcag taagtgcctc aacggtcaat aaatgcttta agctgatacg
    14221 ttctgatttg atgatcataa tgtttcctcc ttagttttct tcgcttcgtg aagtttctgg
    14281 taagataaga tttaaaatga tgccaagtac agttgctaat gccattgccg acaatgtaaa
    14341 tgtgcctact tcaaagacga gtccgccaat tcctactact aagataactg aagcaatcaa
    14401 cagatttttc tttttatcaa aatcgatttt gttctcgatt aaaatcttca ttccacttgc
    14461 ggcaattact ccaaataaga taaaactgat tcctgagatg actggtccag ggatacttaa
    14521 aatcaaagcg cttaattttc ctacgaatcc taaaatgact gcaaatactg cagctccacc
    14581 gatcacaaac acgctatgga cacgtgtgat agccagaaca ccaatgtttt caccgtaact
    14641 tgttacagga ggacctccga caaaggctgc cacgatttgt gctaatccat cacctgtcaa
    14701 cgtcttatga agacccggtt cttcaaagaa attacgttta gttagtttat tcaataccat
    14761 aagatggccg atatgctctg tcatcgtcac aaaagcgatg ggtgccattg ttgtgattgc
    14821 tccaagatat agctttggtt catattgtac aaagggaatc tcaaagttag gaacagcaaa
    14881 ccaggcagcg tctacgattg gcttagtatc cacgattcca aacagcaagg ctacgatgta
    14941 tccgctaata atacctagta aaatcggaat caatccgaga aaacctctta gccacatgtt
    15001 gaagaaaatt gttaatccta atgtgatcag cgctacagca atatacttga aatcatacgt
    15061 gccctgatta tacatagcat ttgttgctgc atttgccgca agtcccaacc cgataaccat
    15121 gatgactgga ccgacgacga ttggaggcaa gattttatcc agccatgctg aaccgatctt
    15181 tttgatgatc agcgcaacaa tcaaatagac taatccagtt gtgactgctc cttgtgcaat
    15241 cgctggataa ccatctgttt tcatcaaaag ctgcatcgct gcaatgaaag cgaagctgct
    15301 tcctaagtac gcaggtatct ttcctttagt agtaaataag tacaccaatg tacctagtcc
    15361 tgaactgact agcgcaatac ctggatcgat acctactaag atggggacta acacggttgc
    15421 tccgaacatc gtgaacaagt gttgtaaact taatcctacc caatgtcctg gggttgggcg
    15481 atcgtggata tctaacacca cgtcatcatt atgaaatcct tttttctccg acatgtttct
    15541 ctctcctcta atcttcctct ttcaaaatca tgatgcgatc ttgtccatca agctcttgca
    15601 tctctactaa aatctcttcc gcccgagatg ttggaatgtt cttcccaaca taatctgcac
    15661 ggattggcaa ttctcgatgc ccacgatcga ccaggactgc taatgaaatt tttcttggtc
    15721 tgccaaaatc cattactgcg tccattgctg ctcgaatcgt tcgtcctgta tacaaaacat
    15781 catcaatcaa aataacttct tttccttcta aggaaactgg gatgtcagaa gaatgaagtt
    15841 ccggttcttc tggattttct tttttgtcat ctcggtataa agtgatatcc agttctccta
    15901 caggaatatc gatatcttct agctgcttca ggcgttcggc aattcttgat gcaatgtaga
    15961 ttcctcgtgt tttgatacct accaatacga tatcttggat actatggttt ctctcgataa
    16021 tctcataagt aattcgagtc aatgctcgct tcatggttac ctgatctact acttcttttg
    16081 cttgcatttt cattccccct acttttttgc ataaaaaaac tcctgcccta agaggacagg
    16141 aggaatgttt agactgagcg tatactgata cactgatagc tatactatgt caatgagcaa
    16201 tctacttatg gcgcaccata cgtatccttg ctcccaccct tcttagcctc acgggactaa
    16261 acttaaagga attctattaa gttttatgct ttcgttgtta attactatac cgttatctaa
    16321 attaaaatgc aatgtttttt cttaattttt ctaaagtttt ttcaaaaact tctggaagag
    16381 gtgcttcaaa gatcatcttt tcgtttgtag tcgggtgcgt aaaacctaac atttgcgcat
    16441 ggagaaactg accattgcct ttcaaagttt tcttcggtcc gtatactgga tctccagcta
    16501 acggataacc gatatacttc atatgcacac ggatctggtg tgttcttccg gtttctagtt
    16561 ttaattcaac cagagtaaat ccttcgaaac gttccaatac agtaaaatgt gtgacagccg
    16621 acttcccatc ttctcttatc gcctgcattt tccggttttc cttcgaacgg ccgattggcg
    16681 cattgatggt tcctttttcg tgaggaatct ctccatggac taaagcaaca tatttgcgca
    16741 aagaggtctt atcttttaat tgctgagcta atgattcgtg tgcctggtca tttttggcaa
    16801 ccattagcag tccggaagta tctttgtcga ttcggtgaac aatacctgga cgaataacgc
    16861 cgttgatcgt agaaagatcc ttgatatggt acatcagcgc attgaccatt gtgccatgcg
    16921 tatgacctgc tgaaggatga acgaccattc cttgaggttt gtttatcacc gctacatctt
    16981 catcttcgta aacgatcgtc aacgggatat tttctgggac cacatctaat gtttctggtt
    17041 cggggatcaa gacagtaatc tcgtctcctt gttttacttt gtaatttgct ttgactggct
    17101 gtccattgac agaaaccgct ccatttttca gccacagctg aatttgcgaa cgactgtaat
    17161 cggtgaataa attagtcaat actttatcga tcctaccaga ttcatggtga atcgtcgttt
    17221 taagttctgt catttttttc tttgatcctt ttcatctaaa ataatataaa ttaacataca
    17281 aatcactcca catacaagtg tcacatctgc tacgttaaaa atcggaaagc tcataaaatc
    17341 tgtctggaac atatctacta catagccaag acgaatacgg tcgataaaat tgccaatcgc
    17401 accagctaga atcaaactca atccaatcat gaaccagcga ttaccttttt cacgattttt
    17461 aatcatcaat gtgagaatca caacgactgc aatgagtgtc actatagtaa agaaccacat
    17521 cttcccttct agcatactcc atgcggctcc agtgtttcga atatgattca gtgacaaaat
    17581 acctggtata agatttttcg tctctccaag cgctagatta tcagtgatcc accatttgac
    17641 caactgatcc actcctacta gcaaagcgct gaatatccaa taaataatta acaaaaaatc
    17701 aatccttttc tatttgttta taaatatcac gaggtcgtac gatcccgagc agattaccat
    17761 cgggattccc atctttagtg ataagtacgg cttccaaagt cccttgctca cgaaacatcg
    17821 cttcaacctc gtaaatatgt gttttagctg gaacaaaatg ataatttgtg tactttccgt
    17881 tttggatgat caaatccaac gctcgtttat ttgttaaatc aaccggacct ttttggcttt
    17941 cttttgctag ccaaaacccg atattacgta aagtaatcaa tgctacaaat tttcctttat
    18001 tgtataacgg aaattgtgaa tacctttttt ctgctactat ctttaacagt tcaagtaacg
    18061 gaagatcttg ttcaaaacct gttacacgtt ttgcaaatcg aggcagcacg gtttcaggct
    18121 gaatcagttc ttgttcgatc agctggattc gcttgactgt ccaatcattt ggctctgcaa
    18181 tgacaaaatc gactgcgatc cgatcatgga cgatcgcatt ccttaactga gcaagctgta
    18241 aaagatcatc ttcgtatttt ctgatcatta attgttttct ttgagctagg cgtctgacaa
    18301 gttcggtaaa tcccatattt cgtgcatttc ccatctcgtc tctcatccat ttttcgattc
    18361 gattgaaact gattaaaaaa agatcagagt ttgccataat tttcctcctt gatcaaatat
    18421 gcccggtttt ttatatagaa aaagaacgca atcaacacaa taactgcaaa aaaactgaaa
    18481 aataaatttt gtaggaaaac ggcccccaac ccagttgcta gaaataaaaa cggatagatt
    18541 tgaagaatca agtaattcat tgtgatcaca taagcaggct ttgcttcttt cactgtataa
    18601 acggggcttt ttagccaata aaaggtgacc tgcatcgtaa agggcacttc cagatcaagc
    18661 gttatctttt gttcatgact gagaacactg cgtttttcat tgttgattct tagctgaatc
    18721 gagctaccca taccgtaaaa accggttttt cttataaatg tcgttttcat cataccctcc
    18781 tattatgctt tagtatagct caaaatacaa taaagaaaaa gaatgatcct agtgtaaaca
    18841 aaattaattc cctatcgtct aaaaaaagaa gctgtagtca aaatacagct ccttcgatgg
    18901 tagattataa tcaagcttaa aacaatccca acacttctcc gtcatttgtc acgtccatat
    18961 tcaatgcagc aggtttttta ggcaaaccag gcatcgtcat aacatctcca gtcaaggcta
    19021 ctaaaaatcc tgcccctaat tttgggatga tttcgcggat cgtgatggtg aaatcttccg
    19081 gtgcacctag cagtgaagga tcatcagaaa atgaatactg tgtttttgcc atacaaatcg
    19141 gcagtttgtc ccatccattc ttcgtaaact cttctatttg tttttgcgct tttttgctga
    19201 aaacaacacc atttcctccg taaattttct tgacgattgt ttctgtcttt tcttgtatcg
    19261 tttcttctag gcggtataat ggcttgtaat tagcttcttt tctatcaatc aatcgtacta
    19321 cagcttttgc taaatcaacg ccgccttctg ctccatctgc ccatacactc gctctcttgg
    19381 caagaatccc ctgattttca cacaagtgct ccaacagtgt gagttcattg tctgtatctg
    19441 ttacgaattc attgattgcg acgatcacag gtagctgata ttgttccata ttacgtatat
    19501 ggcgctttaa atttgcaaaa cctactttca aagcatcaag attctcattt ttaagttcat
    19561 cttttttcat tccgccatgc attttcaatg cacggacagt ggcgacaatc accacagcat
    19621 ccggcgcttt tttcaagtta ggtactttga tatctaaaaa tttctctccg ccaagatctg
    19681 caccaaatcc tgcctctgtg acaacgtaat ctgctaatct caatgctgtc ttggtagcta
    19741 aaatactatt gcagccatga gcgatattgg caaacggtcc cccgtggaca aaagctggtg
    19801 ttccgtaaat tgtttgtaca agattcggct tgattgcatc tttcagcagt aatgccagag
    19861 cgccttctgc tttcaagtct ccagcagtca caggctgacg gtcaaatgta tagccgacaa
    19921 cgatccttgc aagacgagcc tttaaatctt caaggtctgc cgcaagacac aagatagcca
    19981 tgatttcgct ggcaactgtg atatcaaacc catcttctct tggaacacct tggattggcc
    20041 cacccaagcc aacaattact ttacgcagtt cacgatcatt gagatcgact acccgtttcc
    20101 aaatcactcg gcgggcatcg atgttcaatt catttccttg atgaatatga ttatctaaaa
    20161 gagcagataa tgcattatta gctgttgtga tagcatgcat gtcaccagta aaatgcaagt
    20221 tgatatcttc cataggcaat acctgtgcat atcctccgcc tgcagcacca cctttgattc
    20281 ccatcacagg accaagtgag ggttctcgca atgcaataac agatttttta ttgattttat
    20341 tgagcgcgtc tcctaaccct acagtgatcg ttgactttcc ttcgccagct ggtgttggat
    20401 tgatggaagt aactaagatc aaatgcccct cagcgttatc ctttgatcga ttgattccag
    20461 aaaaattgat tttcgcctta tatttcccat acagttccaa atcgtcttcc ttaagatcta
    20521 atttactagc cacttcaaca atcggttcta gctctgtttc ttgtgaaatt tgcagatcat
    20581 tcttcatttg attacccctt ttcacgaact ttattcaaca aaatatcttc tttgttaaga
    20641 tatgccaatt ataccttttt ttattcagaa aaaaaacata aaattacagg tttttaattt
    20701 atttgacgta cttataaata ctctttataa tgaaggctat gatcagactt tagaaaggtc
    20761 gtgagtgctt tgaccacagg aattgtaaaa tggtttgaca acaaaaaagg atacggcttt
    20821 atcagttatg atgacacaga agaaattttt gtacatttta ctgcgattga agaagaggga
    20881 ttcaaaactt tggaagaaaa tcaagtggtc gaatttgaga tcatcgaagg gaatcgagga
    20941 acacaagctg cccatgtcaa gaaaggcaac gttcagacta ccgatactag tatgcatgaa
    21001 tagataaaca aatagagtga gacgctaaac gggatgaacc gtacgtctca ctcttttctt
    21061 ttcctgtaaa aattcgtttt tttaggttct gatttttaaa
//
LOCUS       DAIGTA010000052        20615 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.055, whole genome shotgun sequence.
ACCESSION   DAIGTA010000052 DAIGTA010000000
VERSION     DAIGTA010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.055"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            23..646
                     /locus_tag="NOB43_002038"
     CDS             23..646
                     /locus_tag="NOB43_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982884.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="NOB43_002039"
     CDS             1096..2145
                     /locus_tag="NOB43_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0982885.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="NOB43_002040"
     CDS             2142..3023
                     /locus_tag="NOB43_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982886.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="NOB43_002041"
     CDS             3026..3796
                     /locus_tag="NOB43_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0982887.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="NOB43_002042"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="NOB43_002042"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCI0982888.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNGTDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="NOB43_002043"
     CDS             5107..6270
                     /locus_tag="NOB43_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0982889.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="NOB43_002044"
     CDS             6387..6797
                     /locus_tag="NOB43_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0982890.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="NOB43_002045"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="NOB43_002045"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI0982891.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="NOB43_002046"
     CDS             9370..9654
                     /locus_tag="NOB43_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982892.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="NOB43_002047"
     CDS             9814..10050
                     /locus_tag="NOB43_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0982893.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="NOB43_002048"
     CDS             10047..10445
                     /locus_tag="NOB43_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI0982894.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="NOB43_002049"
     CDS             complement(11112..12056)
                     /locus_tag="NOB43_002049"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI0982895.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="NOB43_002050"
     CDS             complement(12352..13296)
                     /locus_tag="NOB43_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0982896.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="NOB43_002051"
     CDS             13517..14731
                     /locus_tag="NOB43_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0982897.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="NOB43_002052"
     CDS             14753..16768
                     /locus_tag="NOB43_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HCI0982898.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="NOB43_002053"
     CDS             complement(16851..18224)
                     /locus_tag="NOB43_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI0982899.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="NOB43_002054"
     CDS             complement(18250..18534)
                     /locus_tag="NOB43_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0982900.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="NOB43_002055"
     CDS             complement(18536..20551)
                     /locus_tag="NOB43_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0982901.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
BASE COUNT         6777 a         3659 c         4042 g         6137 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgga
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaaactaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgattta tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcacatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaaac cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggt
//
LOCUS       DAIGTA010000053        20293 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.056, whole genome shotgun sequence.
ACCESSION   DAIGTA010000053 DAIGTA010000000
VERSION     DAIGTA010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.056"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(49..615)
                     /locus_tag="NOB43_002056"
     CDS             complement(49..615)
                     /locus_tag="NOB43_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0982902.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(643..2145)
                     /gene="eat(A)"
                     /locus_tag="NOB43_002057"
     CDS             complement(643..2145)
                     /gene="eat(A)"
                     /locus_tag="NOB43_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI0982903.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(2403..3524)
                     /locus_tag="NOB43_002058"
     CDS             complement(2403..3524)
                     /locus_tag="NOB43_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0982904.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3650..4591
                     /locus_tag="NOB43_002059"
     CDS             3650..4591
                     /locus_tag="NOB43_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI0982905.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(4741..5637)
                     /locus_tag="NOB43_002060"
     CDS             complement(4741..5637)
                     /locus_tag="NOB43_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI0982906.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            5906..7246
                     /locus_tag="NOB43_002061"
     CDS             5906..7246
                     /locus_tag="NOB43_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0982907.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            7464..7907
                     /locus_tag="NOB43_002062"
     CDS             7464..7907
                     /locus_tag="NOB43_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCI0982908.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(8411..9829)
                     /gene="nhaC"
                     /locus_tag="NOB43_002063"
     CDS             complement(8411..9829)
                     /gene="nhaC"
                     /locus_tag="NOB43_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCI0982909.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(10232..11455)
                     /locus_tag="NOB43_002064"
     CDS             complement(10232..11455)
                     /locus_tag="NOB43_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCI0982910.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(11486..12325)
                     /locus_tag="NOB43_002065"
     CDS             complement(11486..12325)
                     /locus_tag="NOB43_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI0982911.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(12342..13022)
                     /locus_tag="NOB43_002066"
     CDS             complement(12342..13022)
                     /locus_tag="NOB43_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0982912.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(13024..14097)
                     /locus_tag="NOB43_002067"
     CDS             complement(13024..14097)
                     /locus_tag="NOB43_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0982913.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(14153..14391)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(14434..14667)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14744..15415)
                     /locus_tag="NOB43_002068"
     CDS             complement(14744..15415)
                     /locus_tag="NOB43_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0982914.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(15502..18180)
                     /gene="mgtA"
                     /locus_tag="NOB43_002069"
     CDS             complement(15502..18180)
                     /gene="mgtA"
                     /locus_tag="NOB43_002069"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCI0982915.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            18839..19276
                     /gene="ndk"
                     /locus_tag="NOB43_002070"
     CDS             18839..19276
                     /gene="ndk"
                     /locus_tag="NOB43_002070"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCI0982916.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(19298..20164)
                     /locus_tag="NOB43_002071"
     CDS             complement(19298..20164)
                     /locus_tag="NOB43_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0982917.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
BASE COUNT         5823 a         4236 c         3579 g         6655 t
ORIGIN      
        1 caaaagcagt gccttgaaat attttattta aataacacaa aaacataatt actcataaga
       61 aaccaattct gtattatcta ccatgaatgt aaagaacccc tcattaggca tcggatgaaa
      121 ataagcattg atcactctta tcaaggcatt atggcaaact aacagataga cattttcttc
      181 gtcttcgatg cattctttca ataaaggaac gatccgtgca tacacatcta agactgactc
      241 cccatttggg aatcgtacag cgaacgctaa acgtgctttt tgaaagttct catctttgct
      301 tggcagtcca tcataatccc caaaatccat ttctaccaat cgttcatcaa cggtcagcgg
      361 caagctgaga cgatcagcaa ctgcttgtgc tgtatctctt gctcgttgaa gaggggaatg
      421 gatgattttc gtgattggaa caggcaaatc tactaccttt tctgctagtt tctgtgcctg
      481 catctgtcct ttttcagtca gcggcacatc tgcccgtccg caaactaatc cttgtgcgtt
      541 ccaagttgtt tctccgtgtc tcgttacata aagcatgtga ttctctcctt cgttggcaaa
      601 gttcccctta accatacctt gttgttcttg agattacaag ggttagattc tctcaagaga
      661 aataatctca gtagatactt tatccaggaa ggtttgatca tgttccacta gtaacatggc
      721 aggtttcacg ttcaagatca gttgttctaa ttgttcttga ttgaagacat ccaaataatt
      781 caatggttca tcccatgtat atagttcagc tggctgtgat aaagatttag ccaattccac
      841 ttttttccgt tggcccatac tcatctgctc gatcttgtta tgaaaaacat ctctttccat
      901 cccaagcttt cggaggttgt tcaaaaatgc ttggtagtct acttggtttt tctctgcaaa
      961 ttccgccaac gttcctcgat tgtcttcata attttggctt gcataactaa tgctcagatg
     1021 ttttggctgg tatttttctc ctataacctt gccgttgaat gcccccagaa gataatggat
     1081 aatggatgac tttcctgcac cgttaggacc tgaaatcgcc acccgctgat gaggctcgat
     1141 tgtaaaatga attggctcga ataacagatt ttcataccct aattgaagat cttctacgct
     1201 taaaagtcgc ttatggtgag acgcttggct attcatcgtc aaagaatcga tatattcgat
     1261 atcttttaat agtttttctt tctcgctgat ctgggtctcc atccgattca cgattgcttt
     1321 ggatcgtttc atcgtccgtg cagcatcagc acccactgct cctttattca ctcgtctaga
     1381 ttcagtatcg atgaatccga cttgtttctt tgttttatct ccttctcggg aacgagacca
     1441 ttcggctttt tcagctgctg ttttctttag cctactgact tcttttttca atttttcatt
     1501 ttgagccatt tcaaattcat cacgaagttt tttctgttct tcatagatag agaaattccc
     1561 ttgataaagt tccagttgac ttttttcgat tgctaaaaca tggtccacta cttcatcgat
     1621 aaatccccgg tcatggctga ccacgatgaa gccttgtttt ttctttttca aataagccgc
     1681 tacttgtttt ctaccagaga tatccaaatg attcgttggt tcatcgatta acgggaaatg
     1741 agtgtcatcc acaaataaaa gtgccagtag gacttttgtc ttctctcccc ccgatagtgt
     1801 gctgaattct ctccataaga tttcaggatc tgtttgcatc aattggagct ctctttcgat
     1861 ttcccatatc tcaaaatccg taatatcatt taacacgtaa taggttaaac gttctttatc
     1921 ttttgtctgt tgcgggaaat aggcaaattc ttgctgatgg attacttgcc cttgataagg
     1981 tagtttgttt tgtagaatat tcagtaaagt tgtctttcct cgaccgtttc gtccgataag
     2041 tcctagtttc cattgtgtgt caaaatttag atttgcttgt tcaaataata atgtgccttg
     2101 gctgtcgtag ccgaatgtca gattttttat ttcgatttta gacattttcc atcacctcgt
     2161 aaaaaaagac cagtcctatt ttcagaactg gctaaagagg atgcaagggt tggatacaca
     2221 caaaaagacc catacatcga aaaaaccaag ccaatcccga aaatctgcac actgcttcct
     2281 tgtctccaca aggtacagtc tgaatgcagc tttcatcaat cgacttaatt tttcaatgca
     2341 cggatccctc actttgtcct atatttgaaa ttacgatagc ataaagaaaa tgattttgtc
     2401 aactacttcg ggaggatggt gaaaaatctg ctaagtgtct gtcctaagat ttttgttttt
     2461 tctaatgttt gcctgtgttc cattgcttct tctaaaccta ttggacccaa atgaatactt
     2521 aagacaattg ggagaaaatc agaaagtcct tctagctctt ggtctctact tccgcaaata
     2581 gcgattattg gttttcgata tttttttgca agcactgcta caccgtatgg aacttttccg
     2641 tggatcgttt gctgatcgat ccgcccttct cctgtaatga tgacatctgc ttgttcgatc
     2701 tttttttcca atccagtgat ttggctgact aaatcgaaac cagaaaccat cttcgctccc
     2761 aacaaaaaaa gggctccacc aataccgcct gctgctccac ttcctggaat atcatctaaa
     2821 tccacctccc agaaatcttt tatttgctga gcaatctttc ctgcttgttt atctaagaaa
     2881 gctagcgtcg tatctattcc tcctttttgt cttccaaatt gccaagcagc tccttgttga
     2941 cctgtatatg gattggtaac atctgcagcg ataatcaatt ttactttaga aacaagaacg
     3001 tttcttcgat caaaatgaag ttttttagta gataataaag gatttccttc tgtgtaccct
     3061 tctaaagaag cacccaagga ttggagtaat cctagaccac catcgctaca cccgcttcct
     3121 cctaaagtga caataatttg ttctacttct tgaagcagtg catctttaat aagttctcct
     3181 aaggcataac tggaagcaag tcggatagtt tgatccgttg gtttatcaag tagatctaac
     3241 cccaatgctt gtgcagattc gatgactgcg gtgttttttc cttgccaagt tgtcaataaa
     3301 tagctgattt ttcgctgacg gaataagaga tccatcccat caatggtacg ccatgttccc
     3361 ctgagcgcgt aatagattgc ttctgcagta ttttctccgc catctgcaat cggcacattg
     3421 atttttcttc ctttacgatc ttcccagcca tttagaactg cctgatttag ttcaaatgaa
     3481 gaagcacttc ctttaaatga atcaattgcc gccaaaatat ccatctgtat ccctcacttt
     3541 cttcttaagt aagacacttt ttttcatttt tttcaaacaa aacaatgcta ttttcttcca
     3601 tttttctata tactaaaagg gaactcattg aataaaggag agaaaaaaca tgaaaatcgc
     3661 aatagctggg gccggagcaa tgggcagccg aatcggattg atgctacatc aaagcggaaa
     3721 tgaggtcctc ttgatcgatc gttggcctgc tcacattgaa gccattcgta caaatgggtt
     3781 gattgctgac tttaacggta aagaagtggt cgcaaaactg ccaatctatt caccagaaga
     3841 aatcatcgaa agcaacgaac acgtggactt gatcgtagca ttaacaaaag ccaatcaatt
     3901 agatgatatg ttttgttcga tccaatccat tattactgac aatacttatg ttttgtgttt
     3961 actaaatgga ttaggtcatg aagatgtact ggaaaaatat gtgccaaaga aaaatatctt
     4021 atttgggatc acgatgtgga cagctggtct agctggtccc ggaaaagtca cattgttagg
     4081 tgatggagaa atcgaactag agaacttgga accagaaggc gaagcattta caaaaaaagt
     4141 tgtagaagtc tttcaagaag caaatttaaa tccgatctat agccataacg ttcgttattc
     4201 catttggcga aaagcttgtg taaatggaac attgaatggt ttatgcacga ttttggattg
     4261 taatattgct gaactaggcg cgcaaaaagc ggcagagagc atggttcgaa caatcgtatc
     4321 tgaatttgct tctatcgcag caaaagaagg aatcatacta gatcaagaag aagtgtacca
     4381 acatattgct tctacttatg atcctgacaa catcgggttg cattacccat ctatgtacca
     4441 agacctgatc aaaaaccatc gtttgactga aatcgactac atcaatggtg ccatttggcg
     4501 aaaaggacaa aaatatgata ttgctacacc atattgtgcc tttttgaccc aattagtcca
     4561 tgcaaaagaa ggaatccttg gcgcagaata aaaggctctc tgatgagaat cagctgaatc
     4621 agcagctggt tctctttttt taagcccaat aaaagatcaa aaagaaaaca caactctcat
     4681 gatgccataa gaattgtgct tgtttgtttc agtacataat ctcttcaaaa tgtaggtttt
     4741 ttatttgttt tcaacagagg agaggtcata ttcgtattgc tcataaatag tggaatcgtt
     4801 agtgataaat cgttttgccc aattttctgc atcataaaat tccaatagct ctgataggat
     4861 tggcttaaat ggtgtatgca gaaattccgg taattcatct aaatcacgtt ctcgaagcaa
     4921 aaaaatattt tcaggacgat aaaaatgata atgagcaatc gcttgattat ccgtcactag
     4981 tttcttttga aaatacatgg attcaaatgt ccgcaaagtc actccttgct gaccctcccg
     5041 caacagttcc agaatcccgc gcgattcccc tgtttttttc aggtactctt cataagtaag
     5101 atatccaggt tgttcattcc ctcgatgtgg aagaatgaaa tagttggtcg taacatctct
     5161 ttttataaat tcctgcttat agctttctgc tcgttctttt ctcccattat tcgttgcacc
     5221 aaaaaataga tccgtctttg gttcgctaga agaaaaattc atatgtttcg aataaaatga
     5281 actattatgt ttcagcccaa gttcttttgc ttccaaaaaa tcaaaatgat aaatctcatc
     5341 gattgccggt tcatcttgtg cctgcttcag catcgcctcg tgttctgctt tgaagtgatt
     5401 ccaaaaaaat aacacaattt ttgcattggt aaatgggcgc acgcgtcgag ccatctccat
     5461 atcaaatcca taatctaaaa aaacgatcag ctgataattt gccaactgtt gtctagctga
     5521 tttaatgaat tccgactgta gtaaatcttt tccggaccaa acatctaaag agcggatgga
     5581 aggcaaaaaa taaagtgatt tattttttgc aactagcagt acgtcatttt tgttcatctt
     5641 ttccgcctca ctttctctgt cactttttcc tatgatagcc tgtttaaata gtaaaaagcc
     5701 agtaaaacgt ttcctatatt tgtatgaaaa tttaacattt gtatgaaaat atgatgaaat
     5761 aaatcattct tctattaaaa ttcgcctaaa agttttctga atagttgtaa ttgtctgaaa
     5821 atttgttatc attagtcatt gttaaatatt gctatttatt cttaatataa attttgattg
     5881 tgaatttaaa agaaagaggt catttatgga agataaaaaa ttgaaaaaac aacttagctc
     5941 cagacatatc accatgttag ctttaggtgg agcaatcggt gcaggtctat ttaaaggaag
     6001 tggcgaagcg attgggatcg ccggcccttc tgtattgatt gcttttttga ttggtgggct
     6061 gattttatat atcgtgatga aaggtctggg aaaaatcgtt ttaagcggtg gcgacacgca
     6121 tcacggatta tctggtttga tacgccctta tctaggtgct cattctgctg attttactga
     6181 ttgggtctac tggtctatgt ggattatcaa tatcatcgct gaagctgttg cagctgcttc
     6241 ctttttgcag ttgtggttcc cgcacattcc agcctgggta tttgttttta tgttggctgt
     6301 tttaactacg atcatcaatc tttattcggt acggttattc gcagaaacag aatattggct
     6361 ggcttttgct aaaatcagtg tcattatctt actgatcatt tttgctactt atcttgtcgg
     6421 tcagcaaatg ttgggcacag gcgttttccc tacccttcag caattgactg accatggtgg
     6481 gtttactcct catggtatga agggaatcat cagttctttg cttgtagtta tctattctta
     6541 cggcggttct gaactgattg ctatcacggt aagcgaagca gatgatccta aacgtgcgat
     6601 tcctaaagca atcaaaggtg tcatgggaag aatcatttcc ttttacatca ttcctttgtt
     6661 tttgcttttg attctttttc cttggaatac tttagcaggc acgaatgtca gtccttttgt
     6721 gatggtattt gaaaaaatga atatcccatt tgcagcggat atcgtcaatt ttgtgattgt
     6781 ccttgctttg ttctcatcta tcaattcggg tgtgtatgca tcttcaagaa ttttgttctt
     6841 ccgtttgaag gatcgaaaag gttcctctag aaaactagct gttttaaaca agcatcaagt
     6901 accgcaacgt gctgttttat tttgtaccag tgttctttat cttggtgtag ctctttctta
     6961 ttttgtcggt gacaaattat ttggctatct ggcaggttcc ctttcgtata cagtattatt
     7021 gatctggatc attatcagtg cggcatcctt tgtactggca ctaagaaaag gaacattatg
     7081 ggataaagga atcagctttt ttgcattagc tgtcttagga ttgattttcc ttggtatcct
     7141 gttcacgaac tccattgggg taactgtatt gactggcctg ctttacctgt tcatttattt
     7201 cagttatcaa aaaaagaatg atgcgttcgt attgacgaat gaatgaaatc gatagaaaat
     7261 tttattttat ttatgtggaa tagatggagc tattgaagaa aggagttgtg acaaaagtct
     7321 tgttgcaact cctttttccg aataaacagt ctcatgacct cttggtaaac ggtgttcaaa
     7381 aaccctctgt gcaaaataat tgattgttct ccatgctcat gacatgatag aagaaaggaa
     7441 tgaaaaaaag gagtttgttt taaatgaaaa agtattggaa gtttttgttg atgatcggtg
     7501 tttcaacggt agttatgttt ggtatgatgt acttgaatgt ctatgcgctc gatcatatct
     7561 tcttcagtcg tacacgagta ttcatggcgt tgatgatggg tgcagtcatg gcagtcatca
     7621 tgctgttgtt catgtggaaa atgtatgaaa acaaaaagat aaatgttatg atcttagccg
     7681 ctagtcttct tgtttttgcc ggttccttgt ttatggtacg aagccaaact actgtcaacg
     7741 acacagcttg gatgaaggcc atgattcctc atcattctat cgctatcctg gcaagtaaac
     7801 gagctgattt aaaagatcct gaagtaaaaa aattagcgga agaaatcatt caggcacaag
     7861 aagaagagat cgacaaaatg aaaaaaatga tcaaagaaat ggaatgacca ttatccgtcc
     7921 aaataaaaaa agaggatgtt ccagaagtta tcagcttcaa gaaataagaa gaagctactt
     7981 ctggaacgcc gtgaataagg ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     8041 ccaaacaaaa atagcttctc ctatttttcg tttggttagg cttattaccg cagatgcaag
     8101 cttttgaaca ccgtttatta agaggttgta aaatcagcgt tctgacctga gtattagaga
     8161 gacaaatgga aaaatagttc ctcatatttt gccatttttt gagctaatac cgagggtcag
     8221 ctgattgaac accgtttatc gagaggttgt gaaaaagtcg cttagtttcg cgtattaaga
     8281 aaaattttgt gaaatggctt tccacatttt tgtataaatt tggcttaata ccgagaaact
     8341 ggcttttgaa taccgtttat tcgtaaaagg gattgtgaca aaagtcttgt cacaatccct
     8401 ttttatgttt ttattgttct aattgcgctg tcttgcttac tgcttcttgc ggtttcacaa
     8461 atttttttga gattccccaa cctgtgaagg cactgaccat cgaaaacaca ggagaaagca
     8521 aactgaaaaa tacgaatggc aagtaagtga gtgtaggaat accaaatgta cttgctacga
     8581 aacttccggc aattccccaa ggcactaagt agttgattac tgttccacca tcttctagcg
     8641 ttctacctaa tacagttgga tcaaatcctg ctttttcata agtttcttta aatgcattac
     8701 caggcagaat aacagatagg aattgttcac caataaaaat atttactccg atacttgtca
     8761 tcaatgttgt aaaaatcaaa tttggtgtgt tcgtcatctt tcttgatact cgttccatca
     8821 cggttgagat caagccaaat tcgatcaaca atccacctaa tgacaaagtt agaataatca
     8881 atgacacagt aggcatcata ctttcgattc ctccgcggct aagcagtgaa tcgatttgtt
     8941 ggtttccagt atttgaaaca aaccctgatt cgatgacccc agccaacttc gttaaggaag
     9001 tttgtgggtt ttgaataaaa atcattccta ctgctacagc gatattcaac aaaatcgtta
     9061 aaattgccgg cacctttttc catgcacaca gtaacattaa aaataaagga atcagtgacc
     9121 agattgaaat agtaaagttt gcttctagaa catcagtcac ttcacgaata gatgaaagac
     9181 ttgcggcttt acttgtgtgt cctaaaatca tgaataaaaa gaaagaaaca acaaatgccg
     9241 ggacagttga ccacatcata tgcttgatgt gtttgaacaa atcggcatca acaatagctg
     9301 ctgctagatt tgttgattcg gataatggag acatcttatc tccaaaaacg gcacctgaaa
     9361 caatagctcc aacaaccagc gctggattta agcctagtgt tgtcccaata ccgaaaaatg
     9421 caatcccaat cgttgacata acagtaaagg cactccctac agcgctacct acgattgcac
     9481 acacaacaaa tacagaaggg acaaaccact ggacactgat caatttgaac ccaatgacca
     9541 ttagagttgg aatgatccct gcttgtatcc atacagcaat caatgaaccg actaaaataa
     9601 aaataaagat tgggatgatt cctggtttga tgccattgat gattccttcg tgcagccaat
     9661 ctgtcgggta tctttttatc actgcataca acatgaccat tccgatcgct gctaagatcg
     9721 tgatattagg tgagaccttt aatccgacaa cgccaatcgc aatgcctaaa acaataacca
     9781 ttaatacaag tgttgcttct aaaaaacttg gtgttccttt ttttcccatg ataatctctc
     9841 cttttttagt tgttcttatg ttctaaaaaa gttaagatat cggattactc cgccgcaatt
     9901 catccgcgat tcctccttta taaaaataaa aagacctgtt ttaaactaag gacgaatgac
     9961 tccgcggtac caccttaatt aaaaacagat ctgtttttca ctttcaaact tttattcaaa
    10021 tgtatggact ttccatgtaa ttcgtcaatt aggcttgatc ggttcacagc gaccaccgac
    10081 tttctgaaca aaacacctaa ccgctactgc gtgaaaagtt gacttgtacg aagtttacct
    10141 tccataagat catttgtcaa tgaaaaagaa aatatttttt catttttctg aaaattattt
    10201 ttataacttt cacacacaag tttatttttt actagaaagt agcgccctct tgtttttttc
    10261 ttgctactat ttcttgatgt tcttgcttga ttctttctaa tagctttggc tctttcaaca
    10321 gatcaagagc tgtattggcg agtagttctg ctgcaatcgc aatagaagca aggcctttgt
    10381 cacttttagc agcagctttg aattcttctg tgtgtccggc aatatatgtc tcagagattg
    10441 ctaccgtagg ctggattgtt ggtatgactt ggctgacatt tcctacatca gaagaaccga
    10501 gacttgttct ttgttccgtt tctatttctt catctggaac acctgcttct tttgcatgct
    10561 ggaagaataa gtcatcaaaa gaaggagtaa cgatgacatc atcaactgca ttttggaaca
    10621 atccaaactc aaaagtcgtg cccgtactta tcgcagcacc tcgtacgata ttttccactt
    10681 tttcatatac tttatctaat gtttgccgat ttcctgcacg taaatagaaa cgtccagcag
    10741 cgtaatctgg aatgacgttg gcagctactc ctccgtctgt aatgatccca tggatattga
    10801 catcttttgg caattgcaag cgtagagcgt tgattccatt aaacacttgg atcaatgctt
    10861 ccaaagcatt tactcctttt tcaggtgctg ctgctgcatg ggaagcgaca ccgtaaaatt
    10921 tgatgtcgac tggatcattc gctaaagatt ctgtcgtttt cccataacga aaagctggat
    10981 ggacgcataa cgctacatcg acatcctcaa aaaaaccttc tcgaacaaag ctgcctttag
    11041 ctgatccgtt ctcgccccct tcttcccctg gggtgccata tacacggatt tctccaccag
    11101 tttcatcaat gaattgcttc actatgctgg cggctaatac ggagtaagta ccaaacaaat
    11161 tatgcccgca tgcatgacca atacctggta aagcatcgaa ttctgccaaa aaggcaattg
    11221 tgggaccggg tttattggaa atataacgtg catcaaaggc tgttcggtgt ccagctactt
    11281 ctttttctac ccaaaacctt tctttttcta attgtttaat caacgctgct gaggaataaa
    11341 actcatagtt acttacttca ggatgttcgt ggatatctag agcaagtgct tgatattctg
    11401 gtaaacgata ttggattaga tccttcaatt ggtttgttga gattgttgtt gtcataaaaa
    11461 attcctccta tgctagtcat ttttcttatt ttctcccgaa tgtttcccat gcaggcacgc
    11521 ttgatccttt tgatgttttc tcgattactt tgactgtgtc ttctgtttga taagcgtcta
    11581 ctattttttg atacgtttta ttgttttcat cttcttttct tgcaacgatg atattcacat
    11641 aaggacgtgc atggtcatcc actggttcta agaagatggc atcagaagca ggattaaatc
    11701 cagcatctac agctacaccg ctattgatca ctgaaatgtc tacatctgac aaagcacgtg
    11761 ctgtttggga agcatctaat tcagaaatgt ctagattttt tctattctcg gtaatatcag
    11821 aaacagtggg cgcttgtcct tttgccttat ccactttgat caatccagca gtttgcaata
    11881 acagaagagc tctgccgcca tttgtaacat cattagggat tgctactttt gctccgtctt
    11941 tgatatcagc tacatccttc aaagtgttag aataaattcc cagcggtgca ttgacagtat
    12001 ttccgatcga tactaaatca gttccgtgtt ctttattgta attgtctaaa aagaattgat
    12061 gttggaaaga attcaaatca atcgatccat ctgctaaagc cacatttggt tgattgtaat
    12121 ctgtaaattt cacgtattcc aaattaatgt tctccttttt caaacggtct ttcacgttgt
    12181 cccatacatc tgtatcttct ccaataatcc ctagttttac gatagtttct tttttgtcag
    12241 ttgtatctgc ttttccttgg ctacaccctg ccaaccaaat aattgctaca aatgtaatga
    12301 ctacaaaacg aataattttt ttcatttttt ctcctccact ttcaatgtgt aattttttta
    12361 atcagttgat tactgataaa ttgacttaaa aaaactaaga ttagaatcaa taatgtagcc
    12421 acaatcgtta catctgtttg gaatcgatta taccctctcg atatagcaag attccctaat
    12481 ccgcctgcac ctactgctcc agccatggta gtcagtccga tcacgttgat gatagtcaac
    12541 gccgagaccc gaatgatacc aggcaaacct tctaacaaat acacacgtaa aatgataccg
    12601 attggactgg ttcccatcgc ttctgccgct tcgatcaccc caggatcaac ttctagcagt
    12661 gcgttctcga tttgacgagc aaaaaacgga acaactccaa aaatcaatgg cactaaagct
    12721 gctttcgcac caatcgtcgt tccaactaag aaacgagtag tcaatgctaa aagagaaagc
    12781 aagataatga aagggatgga acgaatgata ttgatcagct tatcaagtat ttcaaatagc
    12841 agacggttag ctagtaatcc attagggcgt gtcactacta acgtcacacc taagatgatt
    12901 ccaatcatcc cgccaatgaa tgctgtccaa aaagacatat atagtgtttg cttcgtcgct
    12961 tcgacaaatt catccggaat caaataaaca ttgggcaaat atgttttaaa gaaatcagtc
    13021 attttatctt cctccttcga tcactttgat acgactatct aaatcgtttt tttgtaaaat
    13081 atttattttt acaccagatt tgatcaaata atccaatgct tttttccgct gtttggtttc
    13141 tccagctaaa gtaacgatca aactccctaa cggcgtttct tgtaataact ctacattgcc
    13201 atataaaata ttcgctgtta cttgatattt gctgtacaga tgagcgatta gaggttcgtt
    13261 cgtctgattt ccaatataac ttaattccac cagccattta ttggcgatct gatcggcaaa
    13321 agcagaatgg gcaatgatcg tttctaatgc ttggtcaaga tgagtagctg ttcgaataaa
    13381 atctttggtc aattcttctt caggattgct gaagatctgg atgctgctac ctttttcaac
    13441 gattcttcca tcttccataa ccgctacctt gttgcagatt tctttgacaa cttgcatctc
    13501 atgagtgatc aggacgattg ttaaacctaa ctggcgattc aattttttta acaatgcaag
    13561 gatctgaagg gtcgttttcg gatcaagtgc actggttgct tcatcacata ataatacctt
    13621 aggttcattc gccaaagctc gtgcgattgc tactcgttgt ttttgtcccc ccgacagttg
    13681 tttaggataa gcagatgctt tttcttccaa accgacaagt tccagtagtt cattcacttt
    13741 ttgacgacgt tcctgtttcg attttccaga atactttaaa gaaaaatcaa cgttgtcaaa
    13801 aatagttcgg ctttccatta gattgaaatg ctgaaagatc ataccgatgg cctttctttc
    13861 ttttcgcaat tctttgggag agagctgact cagattcgtc tgattgacaa tgacttctcc
    13921 tgctgttggt ttctgcagca aattcatcac acgaactaac gtacttttcc ctgcacctga
    13981 gtaaccgacg attccataaa catcgccttt ttcaatcgtt aaatctacag aatctactgc
    14041 ctgtatctct ttttcttttt gtttgaaaca tacagaaaca tctcgcaatt caatcattaa
    14101 aattcctcct tatctaaaaa aagcgtcctc aagaaaatga aaatgtcatt ttcttgagga
    14161 cgcttttttg cgtgttacca cctcatgttc aagctgtgtt cacacacaac tcctcttcaa
    14221 gtacgatcat actctagcaa gatatcggtc gcagccgtca tcgccttaca tctatgctcg
    14281 ggatgaattg ctcgatggcc attttccaat agtcgttcct tgcttcttct cagctaccga
    14341 agctctctgt caaaggttct tctatcgtac ttaccatttc aatgcaaata atattcaaaa
    14401 aaaaagtcct tttactaaca taaactatgt cagtaaaagg acgacgtatc gcggtaccac
    14461 cttttttcgg aagtttcctt ccctcaagcc caacatctct aaaagagaga ttggcgttcg
    14521 ttttaacggt cgaacagttc cgaatttgcc tacttatcga caaattattc tccaaggcca
    14581 ttttcagctt ttcttacttg actcttctca ccagccagag cctctctgca aagtttccaa
    14641 acttactttc cttttcaacg aaatcgatat tttgttgttg ggattaatct acatgaggaa
    14701 aactgaaaag tcaagtacga aattcaaatt attttttcta tatttatttt tctgtttttt
    14761 tatttaacat ttcaataaca gttcgaagat cttttccttc cgcaagaagt ttcaattttt
    14821 ccttttcttc gacggtataa tttcggacaa aactggaatc aggtatcaaa acaacgccta
    14881 atcctgctcg tgaagcagct gttgctccta ctaaagaatc ttccactgca aaggctgaac
    14941 tagcttctaa tcctgttcgt tccaaagctg tcagataagg aatcggtgaa ggcttgttct
    15001 ccgacacttc gtctccgaat gtaaacgtgt ccaagtaatc agctaattta aagtgatcca
    15061 agatatctgt tgctcttttc gtaacagtgg tcgtagcaat gcctagtttc atatgacgtt
    15121 cttttaagtc tgccaatatt tcttttgcat atggttttaa gtggatggct ccgcttgtca
    15181 gctgttgata aaaatattct tcacgcttcg ctcggacttc ctgtactttt tcagggctac
    15241 ctgctgcttt cactaaaata tcaaaacttt gtttccagtt ttttcctccc caagcgtcaa
    15301 cgatttcttt tgggatatgg atatcaaatt gctgaaatcc ccaaagccag ccatcacgat
    15361 acgttttttc tgtgtcaact aacaaaccat ctaaatcaaa tattgcacct ttcatctata
    15421 cattaatcct ttccaaaaca atacacatag tttagcacga ctggtccaaa aagaacagaa
    15481 gcaaagaacc agccttctcg tttataagag ttcttggaat cgacggatat agattttctt
    15541 cacagctgtc acaagcgcca gataagcgat gactgtagca aataaccata accagtaatt
    15601 gccaggaagt ggcatcaagc ctaattcagc accaaaactt gtaaaaggaa ggacagaacc
    15661 gacaataatt cctaatgtag tgataacaaa catggcaaat gttgcgttgc tttggataaa
    15721 tggtactttc ggtgtacgca gtgcatggag cactaaggtt tgtgtccata gtgattcgac
    15781 aaaccatcct gcatggaata atgcgatgaa aatcactcgc tgtgaactat ccaatgtatg
    15841 gaaacttccg cccactacag caggacaaat aacaaaatac atcaacaagt aagtagtaat
    15901 atcaaatatc gaacttgttg gaccaaagta aaccatgaat tccccaatac tagatgcatt
    15961 ccattttttt ggctcgtcca aatattcttt atccatccga tcccatggca aggaaatgca
    16021 ggaaacatca tagatcagat tcaaaaacaa aagttgtaaa ggcagcattg gtaaaaatgg
    16081 caggaacgta cttgcaatca gcacggaaaa catattgcca aaattagaac ttgctgtagc
    16141 cttgatatat ttcatgatat tcccaaaagt ttctcgtcca gaaagaaggc ctctttccaa
    16201 aatcgtcaaa tctttttcta aaaggatcac gtctgcagat tctttcgcaa tatccacagc
    16261 tgtatctaca gaaataccga tatcagccac tttcattgca ggagcgtcat tgataccatc
    16321 tcctaaaaat ccgacagtat gaccattttt acgtaaagct gtcgtcaaac gtgctttttg
    16381 ctgaggattc aattttacga atacttcatg gtcttcagct acttgtgcta attcatgatc
    16441 actcatttcc gagattttct caccggtaac caattcattg atctctagac ctacttgacg
    16501 gcacactgaa cgtgtaacta attcgttgtc cccagtcaga acttttacag ctacaccatg
    16561 ttctttcaga gctttcaacg cttgtttcgt tgtttctttt ggtggatcaa ggaaagcaag
    16621 ataaccaatc aaaaccatgt ctgactcatc tttgactgaa aattctccaa cgacgcttgg
    16681 attggtcttt tgtgcgacac caatcactcg taagccatct tcattaagtg actgtacttt
    16741 tgcaagtacg gcttcttttc gttcttttgt taatggtgta acagtaccgc caagatcaat
    16801 aaatttagaa atgttcagca tttcttcaat cgcgcctttt gtgatcattt gtgttttacc
    16861 agctggatca gcaaccacaa cactcatacg acgacgttca aaatcaaaag gaatttcatc
    16921 cactttttga taattgatct tatctgtatc taaagtttct gttgcttcat caatgatagc
    16981 cacatctaac aaatttttca gccctgtttg atagtagcta tttagatacg catggcgcaa
    17041 aacacgatca tcttcatttc cttcacaatc catatgatat tcaagaatga ttttatcttg
    17101 tgtcaatgtc cccgttttat ccgtacataa cacatcgatt gcaccaaagt tctggatggc
    17161 attcaaattt ttgatcactg ttcctttttt ggccatcaca cttgctcctt tgaccaaatt
    17221 cgtcgtaacg atcattggaa gcatttcagg tgttagacca actgctacag atagtccaaa
    17281 aagaaaagct tctagccaat ccccttttgt aagcccattg atgacgataa ctgctggagc
    17341 catcaatgac ataaatttga tcagtagcat ggatgtttta tggatgccta attcaaagct
    17401 tgattgaatt ggtttttcag atagcgtttc tgctacatga ccaaatagtg tttcatttcc
    17461 aacagaaaca atgattcctt ccgcacttcc actgatgaca ttacttccca taaagacaag
    17521 attttcgtaa cttgtttcgc tttgctgatc gtcttcacat actttcgcat gcttttctac
    17581 tggatagctt tcccctgtca atgctgcttg ggaaatgaat aaatcctttg cggacaataa
    17641 acgcatatcc gctggtatca tatcccctgc tgaaagccga acaagatctc cacagacgat
    17701 ttcttccata ggaatctctg tgtactttcc attacgtttt acagctgccg ttactttcac
    17761 aagtgatttc agtttttcag ccgcttgatt ggaacgtacg gactgaatca acgtcattgt
    17821 cccgctgacg ataaccatag tgaagataat ggctacaccg aaaagatctt tatctccagg
    17881 agctgctaat acatattccg tgatgaatga aataattcct aatgcgatca acactaatgt
    17941 aaatggcgtg atgtatgctt tcaatatttc tacaatgaat ggtgtttttt tgccatatga
    18001 aatcgcattt tcaccgtaat tttctcttga acgttcgatt tgttcttctg tcaatccatt
    18061 tgctgatgca tggaatagtt caaataattc ttgtttcgtt tttccagcaa aagctgcata
    18121 gattttttgt gtatctttct ttttttccat ctcaatctct cctttgtgtc caaaagacag
    18181 ctgttctcgc tgcttttggt ctttagctat tcatcggatc gatagagaaa aaactgaaag
    18241 gggctgagaa cagatagata atagccctgg cctttcctct agatccttgt ttttcgaatg
    18301 actgtcatcc atttgttctc atctccttta ctaagtaatt ttaattcatg acttccaatc
    18361 atttttcgaa tagttatttt tccaattaga ccacctcctt tttatttttc accgatgggg
    18421 atttgcggca acaaaaaaac ctctcgccaa atactcagcg aaaggtttga aaaagcatat
    18481 taaaaaaagc ttctcagatc tcatcgttga gttttgacac tgtacaacgt aaaaagcaga
    18541 tacctgcttt tagctacctt atgaaaagcc ttatctcgac aattcctgtt ctacccattg
    18601 gcgtctctcg acgtttttgg gcagtagcct atgtttgtat aggagcctca cctaacaaat
    18661 cttattcggt tttccttcgt taatataaca actaaaaaag aggatgtcaa atcaattttc
    18721 catgtttttc atactttttt taaaatacac acgttatatt cctgtctcac gcggttttat
    18781 ttgtctcatt ttccacctcc cgctataata gaaatatagt aggaaacgag gtgctgttat
    18841 ggaaagaaca cttgttatta tcaagccaga cggcgtgaga cgccatttag tcggaagcat
    18901 catccaacgt tttgaagcaa agggactggc cattgctgaa atgaagtttg aaactatgac
    18961 tcctgaatta gcaaaagaac attatcagca cttgactgag cgcagttttt ttgatgaact
    19021 gatcgattac atgacttccg gtcctgtcgt ttatcttgtg ctggtcggcg aggaagtgat
    19081 cgatatcgtc cgtaagatgg ttggagcaac aaaagctgcc gatgctgttc caggtacgat
    19141 ccgaggagac tacgcgctgc cggggactga aaacatcatt cacgcttctg attcccgtga
    19201 tgctgcggta aaagagatcg cccgcttttt cccgccattc gatataaaca aaccgtctga
    19261 aaaagcggcg aagtgataca aattctaaac tgctggtcta gttgctgggt tcagcaatgg
    19321 ccagcagttt tttctctaag gacctccgtt gattctttcc taacatatat tcgagcactg
    19381 tgaagaattc ttggtagtct ttcgtctttt cttcccctaa agcagcagaa atcaatcttt
    19441 gataataatc tgccatcaat gtttcataga tcactgtact tctttcttta tgtgctaagc
    19501 tccgtttcat atcttcattc acactacgtg cctttttcaa ccgaccattt tctatataaa
    19561 acgaagtcag gttcattaaa aaagtaaaga gatactgctc atgattgttc aactgtgcta
    19621 atcgtcgcat tctttttttg attttcaaat aattgttctc aatgaaccga tcactgaata
    19681 tccaaggaaa atcagctaga atagatagtt caaattgacc atagtctggt atctgcatca
    19741 agtattcttc aatgattcgg cattcataac gtaaaaattc aaattctgtc tcagatactt
    19801 ctgttttttc gaccatgtga agattcaaaa ccaaataata cagatcttct gttttcttaa
    19861 aatgcctacg gttattgctg atctctttat aaggatcaaa gctgtcttct tgtacccgat
    19921 ctagcattcg tctttttttc tttaacttta ttggttcatc cagctggttt cgcatccatt
    19981 catattctgc aagtgtcatg ttcattcgct ctaaaaatga tctcaatgtt acaaatgaca
    20041 tttttttcac tgaatttgtc tcaatcccga ctagagaagt cttaaaacag attccttccg
    20101 ctaattggga ctgtgtcaac ttcttgttga ctcgaagttt cttgatcaat tcaccatcat
    20161 acataatagt tctccttttt aatttaaatt tttccacatt caataaatag atacgttaaa
    20221 aaggaaaaat acacgaaaaa aataaaaaaa tgtttttttc ataaaaaata ccaaccttca
    20281 agcattagaa tgt
//
LOCUS       DAIGTA010000054        19188 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.057, whole genome shotgun sequence.
ACCESSION   DAIGTA010000054 DAIGTA010000000
VERSION     DAIGTA010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.057"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            26..463
                     /locus_tag="NOB43_002072"
     CDS             26..463
                     /locus_tag="NOB43_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982918.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            558..1442
                     /locus_tag="NOB43_002073"
     CDS             558..1442
                     /locus_tag="NOB43_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI0982919.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1666..4833
                     /locus_tag="NOB43_002074"
     CDS             1666..4833
                     /locus_tag="NOB43_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982920.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            4853..5398
                     /locus_tag="NOB43_002075"
     CDS             4853..5398
                     /locus_tag="NOB43_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HCI0982921.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            5426..5881
                     /locus_tag="NOB43_002076"
     CDS             5426..5881
                     /locus_tag="NOB43_002076"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HCI0982922.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            5878..6636
                     /locus_tag="NOB43_002077"
     CDS             5878..6636
                     /locus_tag="NOB43_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0982923.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(6722..7462)
                     /locus_tag="NOB43_002078"
     CDS             complement(6722..7462)
                     /locus_tag="NOB43_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0982924.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            7523..8776
                     /locus_tag="NOB43_002079"
     CDS             7523..8776
                     /locus_tag="NOB43_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0982925.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            9098..9325
                     /locus_tag="NOB43_002080"
     CDS             9098..9325
                     /locus_tag="NOB43_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI0982926.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            9448..9774
                     /locus_tag="NOB43_002081"
     CDS             9448..9774
                     /locus_tag="NOB43_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI0982927.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            9842..10555
                     /locus_tag="NOB43_002082"
     CDS             9842..10555
                     /locus_tag="NOB43_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI0982928.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            10865..11716
                     /locus_tag="NOB43_002083"
     CDS             10865..11716
                     /locus_tag="NOB43_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0982929.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            11837..13702
                     /locus_tag="NOB43_002084"
     CDS             11837..13702
                     /locus_tag="NOB43_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0982930.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            13750..15159
                     /locus_tag="NOB43_002085"
     CDS             13750..15159
                     /locus_tag="NOB43_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCI0982931.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            15267..15968
                     /locus_tag="NOB43_002086"
     CDS             15267..15968
                     /locus_tag="NOB43_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0982932.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            16127..16606
                     /locus_tag="NOB43_002087"
                     /pseudo
     CDS             16127..16606
                     /locus_tag="NOB43_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            17454..18029
                     /locus_tag="NOB43_002088"
     CDS             17454..18029
                     /locus_tag="NOB43_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HCI0982933.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            18029..18469
                     /locus_tag="NOB43_002089"
     CDS             18029..18469
                     /locus_tag="NOB43_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI0982934.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            18485..19186
                     /locus_tag="NOB43_002090"
     CDS             18485..19186
                     /locus_tag="NOB43_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0982935.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         6423 a         3198 c         4123 g         5444 t
ORIGIN      
        1 aaaaaatgca cgtagaagta gataaatgga gtggttttgc aaatttcttt tatttctaga
       61 agttattcac gtatacggat ttgtttttct cacaaataaa aaggcaggaa gtacaatgga
      121 tcatttgtat ataaaatata ttcatcaatt ttccgttttg gtgttaggca cactaattat
      181 agcggggatt gtcgcattta ttattcaagg ccgtgacata ttaacagtac atcaagagtt
      241 tttcagttat gcatttggta ttcctctgat cgctataagg tctgataaca aaaagtggaa
      301 gaaacgctat tacattctct tgctattttt gtgtttttat ctgccaccta agatttttac
      361 tttattaggt atacaatgcc tatcattttc ttttatttcc tatatcattg ttttaatttt
      421 cctcagtttc atagtatgga tgttttatct tgtcaaaaaa taaatgaatg tttcatgaac
      481 agtacttcat cacagcctaa tttttttctt tatgctatcg ttatattaaa gaaatcaatc
      541 agaagggaaa gaaagtgatg aaaaaagttt tattagtggt aaaccccagt tcaggcggtg
      601 aacaagcaaa ggaatttgag caattagcga tagcaaaatt ggaatcggtg tttgatgaag
      661 tggtcgtctt gcatacaaaa aaagcagggg atgcaaaaaa ctttactcgc gaagcggcta
      721 cggaagggta tcatagtgtg tttgtcatgg gcggagatgg aacagtcaac gaaggaatca
      781 gtggaatcgc tgaacaagaa catcggccaa atttcggatt tttcccattg ggtacggtga
      841 atgacttggc tcgagcatta gggataccgc tagaacctga ggaagcgatc aatcattttt
      901 cgattgaatc agtcaagcca ttggatattg gaaaaataaa tgacgactat tttatgaatg
      961 tcgtcgcaat tggctctatc cctgaatcaa tcaatgatgt agatgcggag aagaagacga
     1021 aatttggaaa actagcttat ttcatgtcag gaatcaaaca gttagcttcc acacaatcct
     1081 actcgtttca cgtagaagtt gatggaaaga aggaagaaat tgagagcagt accttgctga
     1141 taggactaac taactcagtc ggcggttttg aaacattact tccaaatgca aaagtggatg
     1201 atggtaagct ccatttggtt tatttaaaag attcttcttt gatcgatacg cttaaaacat
     1261 tgccagacct attaaaagga gtagatgaat ctacgaaaaa tctagcctac cttacttgtg
     1321 agcaattagt tgtgtcatta gctgatgagg aagaattgac gacgaatgtt gatggagatg
     1381 aaggggataa attacctgtg acaatcaaag tattgccctc acatttacag gtttattgtt
     1441 aaaatggagg ttgtgaccga ggagttggcg ggagaacacc gcttgttcgg gataagggac
     1501 tgtgacaaga cttttgtcac agcctttttt ttgtacaaaa aagaaattta cacctaatag
     1561 aaaaattttt ccataaaaat acatatttta aatatgaaag tacaattgga aatagattaa
     1621 aacgataaaa taaaattgtc aaaacgtcag agaggatggt ggagaatgaa tcaatgtgta
     1681 aaaaagctga ttgcgtcgat tttgtttgtc ttccctctct tgatggtgac atccgttttt
     1741 gccgatgtag agaaaacaaa cgaatcaacg caatcagaga atcaaagttt tgacaagact
     1801 actttttcag aagaatcgat tacttctgaa actacagaat ctcaaagtga ggcttctact
     1861 aataaaaggc aagaagaaaa taagacaagt gagacctcag aagtagctga acaaacgtct
     1921 gatagcagtg aagcggcact ggcaagagct gtttcagcgg atgggtacag cgaagctgcc
     1981 acaacagaag aactggcgca gcttctcgca gacgaatcag taactaagat ccgactgatt
     2041 cagcctttga ctttagacag ggaattagag atcaaacgag atatcgttat tgattttggt
     2101 ggattcgctc acaatttcgg cacacaccat atttatatca atgagatacc tcagtcgatc
     2161 gagttccaga attttaaagg aacagctgca catccaggtg gattgacacc aaatatcgat
     2221 ggaaatgcca ttatcattgc ttatatgacc gatttttggg gaagcagata tcattttacg
     2281 ggagaaataa aatttaccgg gacacttgat ttgtatgatg ggtccaaatt aggactgatt
     2341 tacgctcctc gtgcaactgt cacattagat ggtgtttccg gtgtgttgga tgtccaacca
     2401 gtgaaggaag gactgaatgc cgctccgggt aaagcctatt tttgtagaag ctatcaattg
     2461 aatgtgatca atggtagtca actttatgga ccgtatctag ggaaattcta cggttttcta
     2521 gattcaggag atgagactgg tagtggaaaa acagcgccag gaatccatat cttaagcggt
     2581 tcaaaggtct ctcttgatta tgatcgggca gatggcgtta gcgatgaagg agaggcagtc
     2641 gatacgctac ctggtaatgt catgtttgaa gtcagtggtt cgggaagcga attttcggta
     2701 aatacaaaga tcaatattac caatgacaac aatcgcggaa tcatccaaat gagaggttca
     2761 ggatcgaaag tcactgtatc gaatggtggg aaaatcacca tcaatacagc aactacgggc
     2821 ggatttcgct tgcaaggaga ttctagtcaa atccatgtat caagtggtgg acaaatctcg
     2881 gtcaaaatgg ctggagatga cgatcaaccc gggaacaatg ggatgcgttt tgtaggaaaa
     2941 ggcctttctt tgatcgtaga aggagccgga tcagttatcg acatcgataa gcagagtggg
     3001 cgttccagcg cagttcgttt tgagaatggt acgcaaaagc tgacagtaac caatggaggc
     3061 tcattgaggg taagaaatac aggtgatggc aaatcttacg tgaacagact caatcaagga
     3121 aatcaagcga tccaatttta tgacgcttct ggttttctag aaagtccagg ttcagctgat
     3181 tttacagtca ctggagaaaa atcaaatatc gatatacgcg cagattccgg agcaactgta
     3241 gatacaactg gagatattga tttaaatttt acggcaggtg aaaaaactta tttagtcatg
     3301 gtcgggaaaa caggggaaga taagaccggc atcatcagtg gggatgtgtt gaatgtggac
     3361 ttagaatctc ctacctattt tgatttccaa aacaaacgga ttggaagcga gaccaatggc
     3421 ataggcggct gggtattcca aggaaatgga gattcttctt taaagatcgc ccattcagaa
     3481 atcgctttat ggcgaaaaac aggcgcaaca ttcgataact ttgaaaaaga cccggattat
     3541 ttttctgata tgacagactt atcgatcaat gggaccgact taggcaattt cgtatcaagc
     3601 cctagtgcag gtttaacaaa tgaatttgct cagacaggtg ccggaatgaa aaattataat
     3661 cgaatcagtg ccaataatca gctcccgatg attgaatcct taagagtgcc aacgaatgca
     3721 gataaaaaaa tctatgggca tgtcgttgtt cccgaaggtg tcgaggcaaa gccaagagat
     3781 gcttggacag gcgaagtaga agtgacttta cgtattactt acgcagatac gacgaaatca
     3841 tctgtagaaa ttactgctct cacgcaagga caaacagatg aaaatgaagg ggcaggatat
     3901 aacccatggg gagaaggcga acaaggcggc ttgttcgaag ttcaagtacc caatgatgag
     3961 agattaaaaa cggaggatca agtgcaagtt gttgctgcta aaaaagtaag aggtggccaa
     4021 gaagtgacag aactggactc tgccaaaacg acagtcgatg tgattcctcc tgaacctgct
     4081 aatttaagta ccacattgat caatgcagct tctcgcacga tcacaggtac aggtgaagca
     4141 ggagccttgg tttcattgaa aaaaaatcaa gctgttttgt cagaaacaac tattgatgat
     4201 acaggggaat ttgttctttc tatcccagaa aatcaacttt ttgcaggaga tgtattagaa
     4261 attgtattaa acgaccaagc aggagaagct actgctaagg gtgtgcagaa caagccaagt
     4321 accaacgatg aaattgggaa tcacaatcca agtgatacgc cagttgttta tcatgatgcc
     4381 ccgccttttg cacctgctac gaagatcgta gtagaaggtg gtctctcatt tcttgcccct
     4441 tccaaactcg attttggtca gatcaaagca actggtttga cacaagaagc atttggccaa
     4501 atggatatac aggaaaaatt atggatttat gatcagcgag aaacgaaaaa tccgtggatc
     4561 ttaacgataa aattatctca gcctttcaca aatgatgcag gattttctat gcaggatgtc
     4621 ctatatttca agaaaggaga ggagtatcaa ttagtgaatg aagaagaact ggaaattgtc
     4681 agaggacaaa attcaacgaa tgtgcaagca gattattcag aatatttaaa taacggtcgg
     4741 gcgtttaaac ttgtcttaac caaagaaaat cagatagctg gtaattactc agcagagata
     4801 acatggacat tagcagatgc gccgacagaa taaagatcaa ggaggatgat tgatgaatcg
     4861 aatatggaat aaaagtcatc gaaacaactg ctctttactt atgatccttc tccttggatt
     4921 catcctttgg cagacacctg tccatgcctc cgaattcaat tttgcggtag attttgaatt
     4981 accggctaat cagattgata agaacaaaac atatataaat gtaaggatgg agcctgggaa
     5041 aacacaggaa atcccctaca cggtctttaa ccgaacagat aaatcagtaa cagttgagac
     5101 attgatccac tccgctacga cgaattcaaa cggtgtgatc gaatatggag aatcaaaaag
     5161 taaatttgat gaaacattaa gttatgatat gaaaaactta gcaaaaacag tgggagaaat
     5221 aactgttcct cctcaaagtg cggtcactga gacactttca ctgaaagcgc cagaaaaaga
     5281 gctggctggt gtggtcgcag gagggatcac gtttcaagaa aaaaaagaga acgtttctaa
     5341 caaaagtaca gttggtgtcg tcaatcagtt ttctcaagtg aaagcaatct tgatttgaaa
     5401 tagcgaaaaa gagtcttccc cagatttgaa attaaaaaaa gcttatgcgg atcaaagcga
     5461 tggaagaaat gtgattaagg cgaatcttca aaatccaaat gcttcttata tgttcggctt
     5521 gactacatcg gttgaaatct acaaaaaaga aacaaaagag ccttaccttt caataaaaaa
     5581 agaaaaaata gatgtagcac ccaatacaaa ttttgattta cttgtcccat tagaaggaaa
     5641 aaaattagct ccgggacatt atcaagcggt tgtgaagggt gcttggaaag aaaaacgctg
     5701 gaatctccat accgattttg aaataactga tgatgcagcg gaccaattga atgaaaagga
     5761 tattgattta aaaaatcagc cagaaacatt tgactggcga tggctgatac ttgttggagt
     5821 cattcttatt ggcttatttg ctggattatt tattttaaaa gaaagaagga aaaagaaatg
     5881 aaaaaaacaa ttgcattaag taccgttcta gctggaagtc tattattatg tacacaaagt
     5941 gtttttgctg agaataagag ctcagccact acagaaggaa cgatttctgt gaccaaacca
     6001 gatgctgcaa atcctgaaga cgttgttcca gttcctcctg ttgatccaaa tgatcctgat
     6061 actcctttta cacctgacga accaaatcag ggaacatccg gattactgac gattgaccaa
     6121 gctccagatc ttgattttgg aacaatcaag ttaggtacag caaaaacagt atatgctgca
     6181 ttacaaagcg gaacggacag tactggagca caaacacaag tacagaattt cgtacaagta
     6241 acggataaaa gcggaaatta tgccggttgg aaattatcag tcaaacgaac agaatttatt
     6301 ggtacaacat ctgatacgaa taaactaact ggttcaaagg tgaaattcaa aaacgccgtg
     6361 attcgaaata gcgcaactaa tagcagtgga atgccatcta ccgtttctgg aactggcgct
     6421 gaaggaatcg aaatcccagc agatcaggca gtagatctag taactgcagg agcaaatgaa
     6481 gggattggca catggattta ttcattagga gagaatgtgg aacaagggag acaatcagtg
     6541 gaattatttg ttcctgtatc caattatgct gtagacaact acgtttcaac attcacatgg
     6601 tcgttaacag atgctcctac agaagaggaa gcgtaaaatc atatcaacga tttcagggag
     6661 tggagccgat tcaaggccca ctccctgaaa tctgctatgc ttacgtctca gctcttattc
     6721 atcaactcga agcagttttt tggaagtcat ggaaacgttc ctttgtcttt tcaaagatct
     6781 ttcgaccaac gagtaaggag tcaccgttga aaaattctaa cacataatga gcagaatcaa
     6841 ttttctgcaa ttgcgataag ttgatacagt aagattttaa aagtaaaaag taagcatact
     6901 tttctaactc tgtcttcaat tgttttaaag aagtattcac taatttatct tctgtagttg
     6961 ttttgaccat aacttggttt ttcaaacctt tgatactttc aatatataaa atttcccgag
     7021 gatacaggac gagacttcca cctttttgat caataaagat tttatcgaca tttacgatct
     7081 gctgttcttt ccaattgatc tgttctagca cttgacgaat ttgttcagat aaattcctgt
     7141 cttttctgat atatccaatc ggaaggattt tccgattgat gatctctact gcaaaattcg
     7201 tataagcggt gaaaaaaaca atattactat gtgcattttt tttacgtatt tgttcggcga
     7261 catcaatacc tgtgagtgat tgcttcaagt cgatatcgat aaagaaaaca tcgtgattat
     7321 caatagtgcc caactggatc aactgattga tttgagagat agaagtgagc tgcacgatat
     7381 tctcgatatg atgattgacc aattctctga tgatccattc gctgtgaaac tggttatctt
     7441 ctatgataaa atactttttc atatgcaggc tcctattaaa aaaatatgtg tacattttga
     7501 aacaaaacaa tggaggaata agatggtcgc aacagtgaca ctttatttga cctttacttt
     7561 gattttagat ttaggtatct atttattctt ttcgaaacaa ctgctagtaa aaaacagctt
     7621 tggttgtata gctttgatgg tggtgacact tttacttcct atccctaaag tgagctttcc
     7681 ttacctagtt ggcttattat tgatgtttct tttttatttt actacgaaaa acctgtttat
     7741 cagctgtttg atcagtaatc ttttttttgc tatcactgga ctcagctttt ttctggtttt
     7801 tgatctgatg gattatttag gaaagagaca tcttggaaca gcaagttttt ttgcactact
     7861 tatcgcattt attttctatc tattagtaaa aagtatagac aaacagacga gatttctcaa
     7921 cttgcttttt acttatccaa ctgaacacta ttttggaggt atttgtattt tattaagctg
     7981 gggcgtgatt tacttggtat tgggaagtgt tcacttccgc tcatctaatt atctgcttct
     8041 atctcttttg tcgatagtca tcagtttttt ttctttgttt ttttccatta tgttgatcag
     8101 tttccaagta aaagaaagac aacatcagga atcgcttcaa ctgtatcaaa taaatgaaga
     8161 atattaccat catctagagg aattcaaaca tgattataaa agtctactgt tttcattaaa
     8221 aattactctt caggaaaata aaaaagaaac gttggaattt ttagaaatat tagaagatca
     8281 ttctgcagct atttttgaaa aaccgcaaat acaacagcta acaaatattg tatccccagc
     8341 tgtcaggggt gtctttttaa aatttctaga aaaagcagaa tcggagaaaa tcccgatcca
     8401 agtagttatt cctgtcgaag tgaaaacaat cccgattgat ctggttgttt ttattcgctg
     8461 tttatctatt tttatttcta acgcattcga tcatcgtgta gccgatcaga gtccgattac
     8521 gatcaatctg ctggaagaaa aagagggatc acgttttagt atagcgaaca aggcaaatcc
     8581 aacgaatttg acgctatcgg agatggtcaa aagaggaaaa acctctaaaa aaaatggcgg
     8641 gttaggtcta tacagtgcga aaaaaatgtt ggatgtttac gaaaatgcag aactaaaaat
     8701 cgaattttca aaacagaatc actatttttt tgtagaaatg tatctggcat ctagaaagag
     8761 caaatcagcc tactgactta ctgtcaaagg ataagtttga ggaaagtcta cacggagata
     8821 gagacaacaa cacagcatat tcaaaagaaa cagaagcgtg atgaccgttg tcacccttct
     8881 gtttcttttg ctatgtagtt aaacaaagta gttgacactt ccgctactta gtattagtac
     8941 gaaagtatac ttcatgatac taagtagata agaagtgaaa agcggaaccc acgatcgtca
     9001 aaatgctaac tgctttgctt acaccagata aagggaagag caatatcgct tattttaggc
     9061 gtggagaagc aagcaaatcc ctacgatcac aaaaaaaatg ctgacccagc agttaagaga
     9121 gttagaacaa gatgaaagta tccatcgaaa agcctataac caagtcccgc ctaaagtaga
     9181 gtactcgctc accgaagaag gaaaatcatt aagagagatt ctagtagcgt tgtctgtttg
     9241 ggaagaagaa cgtatcgaaa aacaaaaagc ctcaagggaa gaagacacgc tactgcatac
     9301 acatggtggc tacctaaatt attgattttc tatgacattt attttaaata aaagaaaaca
     9361 ggagtttttt taaaagcatc atctattttt tatgtaaaaa aatggtatga ttaatcaagt
     9421 aagaagtgat tggaagaagg caagcaaatg aatagtatgg aaaaagtcaa ccagtttaga
     9481 gatgaacgta attggcgaca atttcataac gaaaaagatt tggctatctc tatttctttg
     9541 gaagcatctg aattgttaga actttttcaa tggaaaacgc cggaagaagt aaaagaaaca
     9601 caattagaac gaatcaaaga agaactggca gatgtattga tctattcata catgatggca
     9661 gacaaccttc acctggatct agatgagatc attgaagaaa aattgatcaa aaataatttg
     9721 aaatatcctg tagaaaaaag cgcaggtgta cgaaaaaaat acacagagtt gtagaaatgt
     9781 gtcattcggc tgttggaaag agcaaaagaa aaacagtaaa atgagtctgg agggagagaa
     9841 aatgaaaaaa aaaggaaaag caaaaagatg gctagtcaat atcctcttgt tcctcttgtt
     9901 attagtagga ctagctttga ttttcaatga acagatcaag gattattttg tcagagagac
     9961 aggagataaa tatgctatag cgaatgtaac aaaagaagat ctgaaaaaga ataacgataa
    10021 agatgtcagt tttgactttg atgcggtaga accaatgacg acagaagggg tcatgaggtc
    10081 gcaaatgaga ggaacagatc taccagtgat tgctagtatc gcagtccctt cagtttcaat
    10141 caatttaccg gttttcaaag gcttggataa tacgtcacta ctttacggag caggaacatt
    10201 atctccagat caagaaatgg gaaaaggaaa ttatgcctta gcaagccatc gtgcaacgaa
    10261 ccctgaattg ctgtttacac cgctagaaaa tttagagatg ggtgccaaga tctatttgac
    10321 agatttagaa aatgtgtata catacaaaac attttttaaa gaaaaagttg ctcctacaga
    10381 tacccaatta ctgaatgaag tcgagggaaa agaaattgtc acactaatta cttgtggcga
    10441 catggacgcc gtcacgcgac tagttgtaca aggagaactg gaaagtgtta catcgataaa
    10501 agatgcgaca gatgatatga gatctgcttt caatctagag acaaaaacat tttaggatac
    10561 tgggacataa gtcgttacag attaaaaaca gccaaaggat atgaatcgat aaggaaaaac
    10621 caatttgctg aaaaaaagag aaacgcaaag aggtgcatct ctgatttggt tgttttctag
    10681 atagacttgt gttccagttt ttttattttt tatatgaaaa ggcttgcata aataaaaatt
    10741 cgatggtatg atgattttga ataagaaatg gattgttact gtacggcagg caaaaccaga
    10801 attcagctaa gaaacagtag gcgaattcta ggttttttta tttttcttga gagggcgaag
    10861 caaaatgaaa attgataaaa ttttgaataa caatgtcgtc atttcgaaaa atggattcgg
    10921 ggaagaagtc gtttgtatgg gaaaaggact agcttttcaa aaaaagattg gggacgagat
    10981 ttcgccagaa gcggtccaaa aagaatttgt tttaagagat tcttttgcta aaaaccaatt
    11041 ccagcagctg atggctgata ttccggcaga ggagatcgaa tgggtcaaac aagtagtcga
    11101 actggctgaa gataaactaa aagttgaatt ttcgcctaat atttatctga cattgaccga
    11161 tcatcttcat tatgcgatca cacgagcaaa agaaaatatc caactgccta atccattatt
    11221 atttgaaaca aaaaaatttt atccgaaaga atatcaagca gcgaaagagg ctcttttgtt
    11281 cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa gccggtttta ttgcctttca
    11341 ttttgtgaat agccaacaag gaaacgaaga catgcaagtg acgatgaccg ctaccacaat
    11401 ggtaagagat atactgagta tcatcagtaa attcttcggc atcgtgttcg atgaagaatc
    11461 tttgaattat cagcgtatca ttactcatct gcagtttttt gcccagcgtt atctcaaagg
    11521 ggaaggatct gacgaacaag atgaatttct ctacgcatta gttcaaggaa agtatccaaa
    11581 agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga caaacgcaaa aacaggaaat
    11641 ggggatcgca gagcagattt atttaacgat tcatattcaa agagtagtaa gtgagaaaaa
    11701 aagcatccaa tcataaggat tgttactgta tggcaggcaa aacctggatt gaaaaaatag
    11761 gttcacgaat gtttgtgact gtttttttca atctgggttt ttatttttta aataaaaaag
    11821 aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt cgtgtatggg aagcggtagg
    11881 aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg cggttgcgat tcagattaaa
    11941 agatgaatct ttagcagata cgcaaaagtt aaaagaagac ccggacgtga tccaagtcgt
    12001 acaaagtggc ggtcagtatc aagtagtgat tggcagtaat gtagcagatg tttatcaatc
    12061 gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga aaagaagagt ccaaaaatat
    12121 tttgaatcgt ctgatcgata ttatctctag tatatttaca ccttttctag gggcgatggc
    12181 agccgccggg gtattgaaag gattcttatc attggcaacg gtgatgggct ggctgacagc
    12241 tgatagcggt acttatcaaa tattgtttgc tgcagcagat ggtgtcttta ccttcttacc
    12301 tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc aaccagtttt tagcagtagc
    12361 aattgctatg gcacttgtgt atccagctat cacagcagtt gctggtgcgg gagaagctat
    12421 cagtttcttt gggatcccag tgattctttc accatctggt tatacttctt ctgtcatacc
    12481 aatcattcta gccgtatggg ttcaaagtaa attagagcca ttcgtaaaaa aagtgattcc
    12541 gcaatttctg caaatgattt tagttccgct tgtcgtttta gtagtgatgg ttccattaac
    12601 atttcttgct ttaggaccaa tcgggacggt tgccggtaat gctttaggcg gtctcttcaa
    12661 ctcgatttat ggatttagtc caatcgtagc aggtctaatc atgggaagtt tatggcaagt
    12721 attcgtgatg ttcggcatgc attggggatt cgtaccgatc atgtttttga atatcgaaca
    12781 atatgggttt gatgtattga tgccaatgct tcttccagcc atcttggcac aaggtggggc
    12841 tgctttagct gtagcattgc gaacaaaaga tacgaaactt cgagcattag ggatttcttc
    12901 tacagtgact tcgttatttg gaatcactga accaactgtg tatggtgtga cattaccttt
    12961 gaagaaacca ttcattgccg cttgtatttc tggaggtatt ggtggagcta ttatcggatt
    13021 ttccggagta aaagctttct ccagcagttt ggtcagctta ttgacgattc cgactttcat
    13081 taatacggtg gatggtgtag agtcaaatgt gacagtagca gtaatagcta caggaattgc
    13141 ttttgttctt gcattcgtag gtacattgat tttaggattt gacgaacaaa cacaagacaa
    13201 tcaattagaa aacaaacatg cgaatgcagg agaaccgatt acttcagcac ggcatacctt
    13261 aaaaagtcct ttaacgggta aagtactgcc attgagtgaa gtaccagacc aagttttttc
    13321 ttctggcgtg atgggaaaag gtatcgctat tgatccagaa gtaggagaac tagttgcacc
    13381 tgcagacgga gagatcacga ctatttttcc aactggacat gctgtaggga tcacaacgac
    13441 tgacggagcg gagattttga ttcatatcgg gatggataca gtagaattaa atgggaatgg
    13501 ctttgagatc ttagtcaaac aaggggatct cgtcaaagca ggagatttat tgattcgttt
    13561 tgacatcgaa gcaattagag cagctggcta tagcgtaatc actccagttg tcattacgaa
    13621 tactgatgca tttgccgata tacttgaatt agaccaaaaa gagattattg caaacgaaga
    13681 tgttctggca attgtaaaat aaggaggaaa tcaggatgca atcacgtttt tcagaaaaat
    13741 ttttatgggg tggagcaact gctgccaaat caattagaag gggcttatga tcgagacgga
    13801 aaaggactat ccgttgcaga tgctatgcct ggaggtaagc agcgctttgc gattatcggc
    13861 agtgaagaat ttgactggac gattgatcaa gaaaaatata tttacccgaa tcatcgagga
    13921 atcgatcatt acgatcgttt caaagaagat cttgccttgt ttgcggaaat gggattcaaa
    13981 tgttatcgtt tttcgattgc ctggacacga atttttccaa atggagacga aggtactcct
    14041 aacgaagcgg gattagaatt ttatgatcag ctgattgatg agtgcttaaa atatgatatt
    14101 gaacctgtga tcacgatttc tcattacgaa atgcctcttc atttggcaaa agaatacggt
    14161 ggctggaaaa atcgaaaact gatcgacttc tatgaacgat ttgctcagac agtattagag
    14221 agatacagca gtaaagtcaa atattggatg actttcaatg aaatcaattc ggcctttcac
    14281 tttccagctt taagtcaagg attagtaaaa agcaatggag caggagagta ccaaaatatt
    14341 ttccaagcat ggcataatca attcgttgca agtagcaaag ccgtaaaaat cggccacgaa
    14401 ttgcgttcgg atatccaaat cggctgcatg attatctatg caacaactta cagcatcgat
    14461 gccaatccag tcaatcaggc agcaacaatg atccaaaacc aagaattcaa ttttttctgc
    14521 acggatgtcc aagtacgtgg agaataccct gcatacacag cgcgtaccca taaaaaatat
    14581 ggagtcgatc cggaaaaatt agagcaaacg gaaaaagact tccagttgct aaaagaatat
    14641 ccagtggact acatcggatt tagttattat atgtctacgg caatcaatga gactgatcca
    14701 caagcagcaa cttcagaagg gaacttgctg ggaggagtaa aaaatccgtt tcttgaggca
    14761 agtgaatggg gctggcagat cgatccagaa gggctgagaa tcgcattgaa tgaattatac
    14821 aatcgttacc agaaaccatt attcattgtt gaaaacggtc ttggagccat tgatcatatg
    14881 gaagaggatg gcacgattat tgatgattat cggatcgatt atttacgtcg tcatatcgaa
    14941 gcgatggcta atgcagtagc agacggtgta gatttgatgg gctatacgcc ttggggatgt
    15001 atcgatcttg tcagtgcatc aacaggagaa atgagtaaac gttacggctt tatctatgtg
    15061 gatctagacg atgaaggaaa tgggacactg aatcgatcaa agaaaaaatc ttttgattgg
    15121 tataaagaag taattgcctc aaatggcgta aacttgtaat taaagcagct gaatgaaaaa
    15181 gaacacactt ctcacatgtg atttgtgttc tttttttatt ttttatgtgc tattctttta
    15241 gtaatagtaa agcaaagggt gacgttatga aaaggacacg tgtactatac ttggaagtcg
    15301 cagataaaat taaagaagat attttctcag gaaaatatcc agtcggttcg atgttgccga
    15361 cagaaagtga attagaagaa ctgtttcaag tcagcaaaat cactgtccga aaggcaatcg
    15421 aactgctggc atcagatgaa tatgtcgcaa agaaaagtgg tcgtgggacg acggttctaa
    15481 gcaatcgtcc ttacaatcga ttatccaaag cggcaagctt tacgcaaatc ttggagaact
    15541 cccgatatga agtccggaaa gaaacgctgg atttgcaatt ggtccatata aagaaggaag
    15601 atcctttgtt ttcctttttc ggtgagcaag ctgtttgttt taagcgctta tattatttga
    15661 acaatcagcc ttatatttat tttgttcatt atcttccaca agaaatgatg caattcagca
    15721 gagaagaatt tggcaaagaa tctttgtatc gtttgctgac gaaaaaagga tatactattg
    15781 actcattttc tgatgatttc tcggcagtat ttttaacaga agaagaacaa ggaattctga
    15841 aaacagacgc acagatcggc atcaaacgga tacggaaatc gtctacgcaa attggggaaa
    15901 tgattgaata ttcggaggcg gtctaccata cggagctgca tccttaccat attgattatg
    15961 aaacataaat aaaaaaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    16021 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc agatacacgg
    16081 ctgtttctgg attaccattt attctggata agggggtgtg gcacgatttt cagaaggaat
    16141 ctatgaacca atcactgtat tgattttagc ttcgatggta accccattcg gcttgacgat
    16201 cgcttatttc ttagggaaaa tcattcgtaa aaatatactc aatcgtcaag aaatcgatac
    16261 attgaagacc gcttttccta tggggatctg tcagatcaca gagggatgtt tccctatcgt
    16321 attgaacgac ttggcacgca atgtcatagc aacgggagtc ggtgggacag taggtggcgg
    16381 attaagcatg ttttggggcg cagatagccg tattccggca tcgggaatgt ttgcagtcgc
    16441 tacgatgacc agaccatggg cattcattgg tgcattgtta gctggttctt ttgtcacagg
    16501 aataaccatt ttattattga aaaaaccagt agatccgaat gcagaaatca tccaagaaga
    16561 aaaagaggaa gaagacatat cttgggatga tttgacaatt agttaggaga ggcagaatgg
    16621 attacaagaa aaaagtacaa tagatgtacc ttgagacagg aatggtatga aagaatcaga
    16681 gttagaaaga atcgaatata cagattttgg tttaggagcg atcgaaactg tccagagcat
    16741 cggcaccctc cttgaaatga cgatgaagga aaaatgagaa cctttcgttg tcgaaagggt
    16801 ctggtatacc ttatgtcgaa ggaaaggaaa caaaaaaact ttcctgtact attccaaaaa
    16861 ggaaagaaag ttattataca gtaaaaaaag aaattattct tcatgctaga gatcagtaca
    16921 cgttcgagcc caatatcaaa cactagttcc aggcaggcgc aacaggtgcg gttatcactg
    16981 aattttcttc cagcagtgac gattcaagtg atatttttac aaatccagct atttatcgtt
    17041 aacaaaaaga tttttaggag aagctgatga acaaaaatga tcaaattttg atcgtttagt
    17101 tcgtcggctt ttttatttag agaaacatca tttatcagtg aaacataaca cgagaacaaa
    17161 atgatttttt cgttaataac agaaacaagt atttgttgtt taaaataata cacgttattg
    17221 gcatatagga cgaaatccca gtatcttcta taagtaagtc atttcatatc gatgaaaaca
    17281 cgttatttat ttttgtttta tctataaaat ggctgaaaaa tgattttttt ctaaatacta
    17341 tatatagtgg cgtctatcct atataccact aaaaaactac aaaatctagt cttttatttt
    17401 aaaaaaacac gtgtagaatg aagatagact tttgagttag ggagtgtttt tttatgaaac
    17461 ttactgtttt ttgcggttcc cgttttggta ataaagaaag ttacaaattt attgcgcaaa
    17521 cgttaggaaa atacatggca caagaagaaa tcgaactggt ttacggtggt tcatactccg
    17581 ggattatggg agtgattagt aaaacagtac tggaaaataa cggaaaagtc acaggtatct
    17641 atccgaatgg gctttttgaa actgaattgc ctggaaaaga tgttactaca tttattccta
    17701 cagaaacgat cgatgaaaga aaggtattat tatttgaaaa gggagatgct gtcctcgttt
    17761 tccctggagg tctaggtaca ttggaggaat tctcacaact tctttcttgg atagcaatcg
    17821 gtctgacgcc cgacaagcca atcggaatat tgaatattgg cggttattac agcggcttgc
    17881 aacaattatt agaaactttt gcaaaagagg attttatgga taaaaaatgg ttggatcaag
    17941 taatcttttc caacaatcca ttggaactgg tcaatgaatt acgagcagta tctattaaaa
    18001 atcagttatt attgaaggag gcaaaataat gagtcaaata tatttagcag gaccattttt
    18061 ttcagaggag caaatcgatc gagtaagtcg tatcgaaaaa gcgttggagg aaaacaaaac
    18121 agtcacaagt ttctactctc cacgtcatca ccaagaaagc aattatgaac tattcagcgc
    18181 tggatgggcg caggaagtat acgaaaaaga tatggaagaa ctgacaaatg cagaatttgt
    18241 tgttgctatc cttgactttg agcatcaaac aatcgatcca ggaacggctt acgaattagg
    18301 tgtggcaact atgttgaaaa aaccgatgat cattgtacaa gaagagacgg tacctacgaa
    18361 cttgatgatt acacaaagtc tccatacgta tttaaaatca gaccaagctg tacgtgaata
    18421 tgattttgaa acattgcctg ttgaaactta cgtaggcgag tacttataga agaggaaggg
    18481 ttgtatgtca gtgattttga tttcaggaac gattggtgca ggtaagagca gtttgacgga
    18541 tatgcttgca aaagagattg attctaaacc attttatgaa aatgtcgaag ataacgaagt
    18601 attgccgctc ttttattcaa atcctgagca gtacgctttt ttattgcaaa tcttcttttt
    18661 gaacaagcga tttttagcaa tgaaaaatgc tttagtgaac gatgacaatg tgctagaccg
    18721 atccatctat gaagatagcc tgttgttcca tctaaacgct gatttaggtc gggtaacgga
    18781 tatcgaagta cagcagtacg atagcttatt agatacgatg ctaaacgagt tagatgatgt
    18841 tgctccaaaa aaacggcctg atttgatggt ccatatcaaa gtttctttgg acacgatgct
    18901 agaacgtatc aaaaaacgtg ggcgtgacta tgaacagcta gaaagcgatg agacgttata
    18961 tacctattat gaaacgttga acacccgcta taatcaatgg tatgaagatt ttgatgtatg
    19021 tcctaaaata caagtggatg gggataaatt cgattttgta gaaaatccag aagatgcaaa
    19081 aaaggtgatc cgtcagatcc aagaaaaatt agctgaattg gaaggaaagc ctgctggaaa
    19141 atattttacg gataaccagc atgcaaaagg tcaagaatta ggctaaaa
//
LOCUS       DAIGTA010000055        18896 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.058, whole genome shotgun sequence.
ACCESSION   DAIGTA010000055 DAIGTA010000000
VERSION     DAIGTA010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.058"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(22..252)
                     /locus_tag="NOB43_002091"
     CDS             complement(22..252)
                     /locus_tag="NOB43_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982936.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(688..1254)
                     /locus_tag="NOB43_002092"
     CDS             complement(688..1254)
                     /locus_tag="NOB43_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0982937.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1254..2210)
                     /locus_tag="NOB43_002093"
     CDS             complement(1254..2210)
                     /locus_tag="NOB43_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCI0982938.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2210..2866)
                     /locus_tag="NOB43_002094"
     CDS             complement(2210..2866)
                     /locus_tag="NOB43_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI0982939.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3236..5254
                     /locus_tag="NOB43_002095"
     CDS             3236..5254
                     /locus_tag="NOB43_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0982940.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5324..5530
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5681..8095
                     /locus_tag="NOB43_002096"
     CDS             5681..8095
                     /locus_tag="NOB43_002096"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCI0982941.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8443..9996
                     /locus_tag="NOB43_002097"
     CDS             8443..9996
                     /locus_tag="NOB43_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI0982942.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10377..12161)
                     /locus_tag="NOB43_002098"
     CDS             complement(10377..12161)
                     /locus_tag="NOB43_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982943.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12176..13897)
                     /locus_tag="NOB43_002099"
     CDS             complement(12176..13897)
                     /locus_tag="NOB43_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0982944.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLTGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13997..14758
                     /locus_tag="NOB43_002100"
     CDS             13997..14758
                     /locus_tag="NOB43_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0982945.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15725..15993
                     /locus_tag="NOB43_002101"
                     /pseudo
     CDS             15725..15993
                     /locus_tag="NOB43_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16665..>18896
                     /locus_tag="NOB43_002102"
     CDS             16665..>18896
                     /locus_tag="NOB43_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982946.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6204 a         3353 c         3786 g         5553 t
ORIGIN      
        1 tctcattaaa aagcataacc attactccga tctgttttta aaattagttt ctacctctaa
       61 tatatatcga gtttttattt tgccttcaga gaatactgtt tctttttttg cagttacagg
      121 ttgtttattt tcggaaaaag ctaatatagc taagattgaa acatccatct ggaatttatc
      181 ttttttactg ctttgatcat aaaagtctgc atattcatca ctgatatttt ttctaataaa
      241 ttcttccatc ataaaaatca cctcaaaacg attatacgaa cttacgttct tgttgtaaag
      301 cgatatttga ggggcaaaaa aggggcataa tttgactgat attaagttag ctattgatat
      361 atgaatgaca tacaaaaata taaaatcttt taaaaatgct tatatatcaa tgtttttgcc
      421 attcttttat atatctgtta tatgtcaaaa aaatgtgttc aatttcaatt tgtatttgaa
      481 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
      541 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
      601 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
      661 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
      721 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
      781 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
      841 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
      901 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
      961 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
     1021 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
     1081 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
     1141 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
     1201 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
     1261 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
     1321 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
     1381 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
     1441 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
     1501 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
     1561 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
     1621 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
     1681 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
     1741 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
     1801 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
     1861 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
     1921 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
     1981 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
     2041 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
     2101 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
     2161 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
     2221 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
     2281 acagccaaga aagactgagt aagtagccgc cgatgatatc agtaggaaaa tgaacgccca
     2341 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
     2401 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
     2461 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
     2521 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
     2581 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
     2641 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
     2701 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
     2761 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
     2821 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
     2881 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
     2941 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
     3001 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
     3061 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
     3121 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
     3181 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
     3241 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
     3301 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
     3361 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
     3421 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
     3481 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
     3541 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
     3601 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
     3661 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
     3721 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
     3781 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
     3841 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
     3901 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
     3961 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
     4021 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
     4081 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
     4141 ggaaaatggc tcttcgacga ataattccgg taacaatacc aactcttcag gaaatgctgg
     4201 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
     4261 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
     4321 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
     4381 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
     4441 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
     4501 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
     4561 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
     4621 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
     4681 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
     4741 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
     4801 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
     4861 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
     4921 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
     4981 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
     5041 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
     5101 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
     5161 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
     5221 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
     5281 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
     5341 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
     5401 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
     5461 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
     5521 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
     5581 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
     5641 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
     5701 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
     5761 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
     5821 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
     5881 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
     5941 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
     6001 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
     6061 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
     6121 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
     6181 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
     6241 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
     6301 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
     6361 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
     6421 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
     6481 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
     6541 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
     6601 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
     6661 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
     6721 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
     6781 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
     6841 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
     6901 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
     6961 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
     7021 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
     7081 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
     7141 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
     7201 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
     7261 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
     7321 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
     7381 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
     7441 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
     7501 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
     7561 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
     7621 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
     7681 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
     7741 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
     7801 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
     7861 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
     7921 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
     7981 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
     8041 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
     8101 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
     8161 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
     8221 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
     8281 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
     8341 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
     8401 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
     8461 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
     8521 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
     8581 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
     8641 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
     8701 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
     8761 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
     8821 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
     8881 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
     8941 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
     9001 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
     9061 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
     9121 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
     9181 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
     9241 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
     9301 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
     9361 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
     9421 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
     9481 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
     9541 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
     9601 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
     9661 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
     9721 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
     9781 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
     9841 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
     9901 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
     9961 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
    10021 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
    10081 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
    10141 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
    10201 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
    10261 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
    10321 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
    10381 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    10441 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    10501 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    10561 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    10621 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    10681 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    10741 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    10801 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    10861 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    10921 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    10981 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    11041 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    11101 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    11161 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    11221 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    11281 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    11341 aaggcgagtt gattaatgaa acgaatggcc ggatagatag cacagttcat aaattgagca
    11401 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    11461 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    11521 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    11581 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    11641 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    11701 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    11761 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    11821 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    11881 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    11941 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    12001 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    12061 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    12121 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    12181 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    12241 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    12301 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    12361 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    12421 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    12481 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    12541 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    12601 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    12661 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    12721 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    12781 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    12841 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    12901 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    12961 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    13021 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    13081 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    13141 aagcataaac gattcccgtg agcaaaaaag caattggagt gacccaagca aatattcggt
    13201 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    13261 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    13321 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    13381 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    13441 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    13501 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    13561 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    13621 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    13681 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    13741 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    13801 gtacacctaa tgtaccggcg atttctaaac agatcatcac aaaggtaagg agagcgagtc
    13861 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    13921 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    13981 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    14041 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    14101 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    14161 tttttataga aaattagata tacctatcaa acagatgaag aatttatatg gaaaaacatt
    14221 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    14281 gatgaaacaa aaacaaaaag agataaggga gcaaaaaaaa cagttgaaat tgatgatcga
    14341 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    14401 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    14461 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    14521 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    14581 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    14641 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    14701 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    14761 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    14821 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    14881 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    14941 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    15001 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    15061 gagaatgata aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac
    15121 attattacaa tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt
    15181 aatcaaatag tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt
    15241 tttgcttata aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag
    15301 aaaaatcaca aaggttattg ttatttttat atattctttt taagaatgat tgttttttta
    15361 tagaaatttt aaaaaataaa acacgttatt gatggatagt tagtttgtta tttggtaata
    15421 ttatagaagt tgactggtag tgatttattt ttcgtcgttt tataaaaatg ttattttttg
    15481 gaaaaattca caaatatgta acgaatgttt ttctggaatt tgctgtgtta aaaagcagta
    15541 tgactaatat aaatactatt gtcatttatg caatttttta tggatagtaa ttttagaggg
    15601 gaatcaatga aggaagaata gaagggaaaa atagttgcaa atacgccagt tagcaaaaat
    15661 agcaatacat cttcaagctt taaaattcga gagaatcatc ttggtagtgg aatcaactac
    15721 aacaaaagga ttaaaccaat taatagatag aattaccaat ggaaaaatag aaaaggtagt
    15781 tattctatac aaaagttgtt taattcgctt cggttatgaa cttagtgaaa ccctttgcaa
    15841 tatatggtac agaatataga aattattgac attacagaaa atgatgaaga tttaatacag
    15901 attgtcacta tttgtagata ccttttacaa ggaaaccgag ccaataaagc taagaagatg
    15961 attaaggagt tgatggaaga cgatacaagt taagaaagtg aaactacgcc caaataaaga
    16021 gcaaaaagag taattggacg tggaaaatgc aagaaatgaa ccatcgattc ggtggacagt
    16081 ttattagtaa tgacggtttg agaacatcca tgacgagaat gaaggaacat cctaaatgcg
    16141 tttagttgaa ccaagtgcca aataatatgg ccaaataagc gatcagttat cgatgaatcc
    16201 caagtattct aaactatata ttcattttga tgctaagcat tgatatattt ttttgggatt
    16261 gatgaaggtt aaccaataca gggactcact gatgaaattc tagagtctga ccttggtatc
    16321 aacgatttag tgattgtttc taatggaaaa gtataaaagt atataagtac attaacaaaa
    16381 taactattag ggttacgctc cagcttgtgc aaggcactgg caggaggaat cgtgaaatca
    16441 taattatggt taagccacac ggacaactaa aagtcataca aagctatcga atcaatcaac
    16501 agaagacaat cggcaatcat tagctttgtt tacagcttac attgcaacgc ttgagttgaa
    16561 ccgaaaatac gagggaggta acgcagccat tttgagttgg ggaatctttt tagaaaatta
    16621 tcgggtacct tgttgtttag tcaaaattat aagggggagt aatagtgagg aacaaatttc
    16681 ataaactgtt aagtatgttt ctagttatgc ttattgtgat caatcaattt gggaacataa
    16741 cggttctagc tgagtcttta gcagaacagc cagagcgttc gctgacgatc gaagttgatc
    16801 aagaggaggc tgctttgggt gagcagttcc agttgcgagt cagaggaaca ccagacctgc
    16861 taaatgcatt ggtcattgat aagagtgagg atttgattga aggggaagtg aagcaactca
    16921 atgattacga acgtctgatt acttattctt cccagcattc aggtaaatac gaattgaccg
    16981 caagaagcgg tgatattcaa tcaaatacgg tctcaataga aatcagtgta ccagaagaaa
    17041 gcacaagtga gtcttttaat gtaccagaag aaagcacaag tgaatctttt aatataccag
    17101 aagaaagctt aagtgaatct tttaatgaag ccagatcatc tgagccatct ataacgcagg
    17161 aatctcagat tgaaagacaa gaggagctct tgaattatga catcggcatc tctgctgagc
    17221 gccccacttt gccgagcagg catacacaaa cgttaaaggg atacattcaa ggaggcgctg
    17281 gcgatattct tgaagaatat ggggagatgg tcgtacgagt tcctagagca tcgattggct
    17341 taattgagtt cattagagtg gaggtcgctg atgattcacc tttaaagcca ctggcatttt
    17401 accaagaagg cacagacgtt gtttttccat ttacctttga ttatgaagga ttaaatgaag
    17461 ccgctcagtc gtatacattc agtatcacgt ttgaagttgc tttctttcaa tcaggcggta
    17521 ctgagccaaa taatgacttt caagtgagtc ttacttatgc tgagcgagca gcaaacacgg
    17581 aattttcaat tacgcctatt ccttcatcaa gacccatttt ttcgaaatta tactatggct
    17641 ctagagaaat cgacagccaa ggaaatcttg ggaatctgct gattgacggg caagacgtga
    17701 ccaacagtaa taaatttatt ttgcaggtaa attatgaagg atcacgaaaa gacggtgtag
    17761 tggttaccga tgtactaccg caaggaacaa ctttggcacc gaatccgact acatggagtt
    17821 ccactggaaa tagagaacct atttcaggtg gggttcggat cgcagaagta acgaatccag
    17881 gtgaagcaaa cgttagaact cattatgttt ccgaggaatt tgtggacaaa gtatctttta
    17941 ataaggaaac gaatacactt gttgtggact ttggtaatct agcagagggt caatcgtatt
    18001 ttattgaata tgctcttgaa gtgaccgatg tcgacttgtt caatgaagga agacaagagg
    18061 atgggttttc tcggaatcga gcgagtatga cctacaataa tcaggtaatg agccgagact
    18121 accgcttgag aatccctgaa agtaatcttc cggcaatctc tttaagaaaa agtgtggaca
    18181 aaaatgttat caatctcaat gaaaatgaac taacgtatac tctgcatgtc tcgatgtttt
    18241 ctggaacaag aaatacgctt gttattgaag atgttttgga agaaggcatg gaatttgtgt
    18301 catttctatc agatattccc tctttcattg atgccgaagt caataatgga atagttcgtt
    18361 tcagtgcgaa taatacgatt ggtggtccga caagttttac cctctctttt aaggtcaatg
    18421 tagaggcgta tgcggtcggc gatcaaattt taaactttgc aacgcttgtg aatagtgaca
    18481 atcgattgaa tacgagtact gtaagaacaa ggaaaatcga tgggcgtatt aaagtaatta
    18541 aaactgatga gaatggccaa aggctggcag gagcaaaatt tgaaatttta tcaagcgatt
    18601 cacaagtgat acaagaaggt ataacggcag aaaacggaga atttttaagt gaaccgcttc
    18661 ctgtaggtag ctatcaagtc cgagaaacag aagcaccgga agggtatctt ttagatgcga
    18721 cggtacatga tgtttttata aatgaatact ccatagaaga agtgacgtta accattgaaa
    18781 acatccttga tacgggtggt gttgaactaa ttaaacatgc tgaaggcagt ggtgaagtcc
    18841 ttcaaggagc tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggt
//
LOCUS       DAIGTA010000056        18002 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.059, whole genome shotgun sequence.
ACCESSION   DAIGTA010000056 DAIGTA010000000
VERSION     DAIGTA010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.059"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            4..2376
                     /locus_tag="NOB43_002103"
     CDS             4..2376
                     /locus_tag="NOB43_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982947.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAESGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVTKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKTGQTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFSLGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="NOB43_002104"
     CDS             2437..3897
                     /locus_tag="NOB43_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCI0982948.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERSNGTYDFDRFYQGKGDINAQILFSYKAEQYYKGYKKHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /locus_tag="NOB43_002105"
     CDS             3908..6112
                     /locus_tag="NOB43_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HCI0982949.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSLLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESYRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYHKAAACTSEACDFRLWTTIAKKKLTATQLKEII
                     QNGRTSQPVKGLKGQKGSFEATIVLKEDFTTSFEFSEKKKTNYKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="NOB43_002106"
     CDS             6128..6277
                     /locus_tag="NOB43_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982950.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6358..6954
                     /locus_tag="NOB43_002107"
     CDS             6358..6954
                     /locus_tag="NOB43_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HCI0982951.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYSKAEWYELGKIEIKSRYGNPVIAYDPERTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTIRSYIMALN"
     gene            6967..7866
                     /locus_tag="NOB43_002108"
     CDS             6967..7866
                     /locus_tag="NOB43_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HCI0982952.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFENRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYEETMDSISNLMEKVI
                     HVEEKERKIAYQRHQQMNREMER"
     gene            7869..8354
                     /gene="ssb"
                     /locus_tag="NOB43_002109"
     CDS             7869..8354
                     /gene="ssb"
                     /locus_tag="NOB43_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI0982953.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGILIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            8720..8980
                     /locus_tag="NOB43_002110"
     CDS             8720..8980
                     /locus_tag="NOB43_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982954.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9427..9633
                     /locus_tag="NOB43_002111"
     CDS             9427..9633
                     /locus_tag="NOB43_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCI0982955.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9633..9857
                     /locus_tag="NOB43_002112"
     CDS             9633..9857
                     /locus_tag="NOB43_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982956.1"
                     /translation="MKTQHKLLNVKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFE
                     DLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            9872..10309
                     /locus_tag="NOB43_002113"
     CDS             9872..10309
                     /locus_tag="NOB43_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982957.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEAGVKPSTIKPSEYQALE
                     LTYGKFIETKKAKTVSSEWLDYFENVNKYGACYIMKKEDNENE"
     gene            10302..11009
                     /locus_tag="NOB43_002114"
     CDS             10302..11009
                     /locus_tag="NOB43_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982958.1"
                     /translation="MSNVVYQLTVEDVSHFLTNKEHLNEVVRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDCKRMPYQRFERKKGQ"
     gene            11390..11569
                     /locus_tag="NOB43_002115"
     CDS             11390..11569
                     /locus_tag="NOB43_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982959.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQELKQKYGKSESRIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            11662..11847
                     /locus_tag="NOB43_002116"
     CDS             11662..11847
                     /locus_tag="NOB43_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HCI0982960.1"
                     /translation="MPLTGKEMLKLLKKNGWVERRQEGSHHHLYKDGVRITVPVHANQ
                     DLGRGLEQKILKDAGLK"
     gene            11881..12312
                     /locus_tag="NOB43_002117"
     CDS             11881..12312
                     /locus_tag="NOB43_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCI0982961.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNLLRSGRNN"
     gene            13249..14523
                     /locus_tag="NOB43_002118"
     CDS             13249..14523
                     /locus_tag="NOB43_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0982962.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLAVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
     gene            14577..16004
                     /locus_tag="NOB43_002119"
     CDS             14577..16004
                     /locus_tag="NOB43_002119"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCI0982963.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPEDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDHLYMKPVRELEQLRVG
                     SGVETKVNLAGEIIIAQDASFKEALIDVLLTKSKNQEIKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            16017..16889
                     /locus_tag="NOB43_002120"
     CDS             16017..16889
                     /locus_tag="NOB43_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0982964.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNELLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            16984..17979
                     /locus_tag="NOB43_002121"
     CDS             16984..17979
                     /locus_tag="NOB43_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0982965.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKDN"
BASE COUNT         6505 a         2883 c         3686 g         4928 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgca
      661 ccaactgatt ctctgaagga gaaagaaaaa gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agagttgatc
      781 gatcaactta aaacgttgga taaccaatac gctgcagaat caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgttacga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgag
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcatgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatt gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacaa ttgaagcctg aagactatcc gaaaatcttc
     1501 ccgaaccgcg tctttgattt tcaattggat aaaacagggc agacagaact tcaagttggg
     1561 attcaagcgg tagccaaaaa tattggaatt caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtacgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagaacaaa agaatattgt tcctgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaattttc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccacagat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaaca tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaatg agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagttaaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtttcgat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagttgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aagtcattta tgaagaagtc gcaaaagaag aaaagatcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaatt ggtttccgct
     3541 cacaaagtaa atgcgtcttt tggtcagcag ctttctgtta acgattcaat agaagctatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagcttgtga acgctcgaat
     3661 ggtacgtacg attttgatcg tttttatcaa ggaaaagggg atattaatgc tcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa agcatgaaca tgaatttgta
     3781 cctgaagtga aaaaggattg gaacgatcaa ttgaagcatg agatccagca acaagaaatt
     3841 agaaagcaaa aacgtgcgat gttgtttcaa caaggcagac aacaagaaag ggagtgagat
     3901 cgtcacgatg aaaactgtca ttttagcaga aaaaccgtca caagcgaagg cttatgccga
     3961 tagcttttct aaagccaccc gaaaagacgg gtattttgag atccaagatc gattgtttcc
     4021 tggtgaaact gtgattacgt atggttttgg tcatttagtc gagttagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacattta cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaac gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgc gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagcag gcgccgatca tggaaagata tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagatg cagaagagac
     4381 ctacccaaaa tttgaagaag cacaagcacg ccagatcgcc gattggttga tcggcatgaa
     4441 cggtagccta ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gtttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttacaggaaa agattagaaa
     4561 cttccaaaaa gaaccatatt ttgaaggaaa agcccaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggtacg atccaccaag ttgaaaccga
     4741 gaaaaaaagt gcggcaagtc cacgtctttt ttctctatcc agccttcaat ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt tgtatgaagg
     4861 aaaatatcta agctatccgc gaacggatac cccttatatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttaaaa gccgaagcga ttccgactcc
     4981 tattcataca ccgaatagtc ggtatgtgaa taataagaaa gtccaggaac attacgcgat
     5041 cattcctaca aaaacggtta tgacagcagc ggcttttgaa caactaagtc cactgcagca
     5101 ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa agtataccta
     5161 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ctaaagacag tcggaaaagt
     5221 accagtagat ctaggttgga aaaagctgtt tggcaaagag agctacagaa aagaaaagga
     5281 agaagaaccg ctacttccta aagtgacaaa aggagaagcg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaacgaagc caccacaacc ttataccgaa ggtacgttga tcacagcgat
     5401 gaaaacagct ggaaaaaccg tggatagcga agaagcacaa tccatattga aagaagtaga
     5461 aggaatcggt acagaagcaa cacgagcaaa tattattgaa actttgaaac aaaaggaata
     5521 tatcaaggta gaaaaaaata agcttgtggt gacaaataaa gggattttac tttgccaagc
     5581 cgtggaaaaa gagccgctgc taacaagtgc cgaaatgacc gccaaatggg aaagttactt
     5641 attaaagatt ggtgagcaga aaggaacaca agctactttc ttagctaata tccaaaaatt
     5701 tgtctctcac ttgttggaag tcgtaccagg acaaatccaa tccactgatt ttggatcgac
     5761 gttacaagag gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt tagggatttg
     5821 tccaaaatgc caggaacaag aagttttact ctatcataag gcggccgcat gtacgtctga
     5881 agcttgtgat tttagattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggaaatc attcaaaatg gccgaacaag ccagccagtg aaaggattaa aaggtcaaaa
     6001 gggttcgttt gaagcaacga ttgttctaaa agaagacttc acaacgagct ttgaattttc
     6061 tgaaaagaaa aaaacgaact ataagaaaag aacacgccgc actacaaaat aatggagggg
     6121 ttatcttatg cgaaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagcaaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa ttgaattaga tcgataaaat cttcctggct attgtatacg
     6301 cataaactta tgttatacta tatttataag tttatacgta tacaaaggag ggagaaaatg
     6361 acaaaagcaa tggtttacaa gctgctagaa gaatttaacg gaactttggc tttgaaggat
     6421 gccaaaaaag cgggcatttc tcctgtaacg atcaaacgta tggtagatcg tggagagctg
     6481 gatcgtgagt atccaggttt tttcacctta cctggtcaat ttcctgatga attgtttatg
     6541 gcacaaaaga aatatgagcg cggcattatt tcgcatatca ccgcgttgga tttatatgat
     6601 ttaacggata tgatccctag acagatcgat ctaaccgtac cttacggtta tcacgtttct
     6661 gaaaaggggt tgaaagaatt cgcagttgag ttacactatt caaaagcgga atggtatgaa
     6721 ttaggtaaga tcgaaataaa gagtcgttat gggaatcctg ttatagctta tgatccagaa
     6781 agaaccttgt gtgacatttg gaatccctgg tacaacgttg aggatgaaat caaagtaaaa
     6841 gcaatcaaaa actacatgga gtcggacaga aaaaatctta gaaaattgaa tgagtatcga
     6901 cgaattttgc ctacagacaa aacgatacgc tcttatatta tggctttaaa ttaaaggaga
     6961 agacacatga cacctacgca attaaaagca aaagtgaaga atatttccag agaaaaagaa
     7021 gttgatccgc agcttgtttt aagacatttt atgatggaaa aattcttgga aaaaatctca
     7081 gagtctcctt atcgtgaaaa ttttgtgtta aaaggcggct tcttaattgg ctcaaagtat
     7141 ggcattgaaa atcgaacaac aaaagacatt gatacgactt tacgggaaat gaaagtaacc
     7201 aaagaaacat tgacaacggt tctaaacgat attttttcaa cgccgacgaa agaaggcatt
     7261 caatttgaga ttcaaggaat gaaagaaaca agggaagctg attattatcc agggtttagc
     7321 ttacgtgtac tggcacattt ggaaaacatg cggccagatt ttaaggtaga cgtgacgaca
     7381 ggtgactcga tctatcctgc aacgatcact cacagtcata aattgatgtt tgaaaatcga
     7441 acgattcctt tggaatctta tcctacagaa caaattattg ccgaaaaatt aagtgcaacc
     7501 tttgattttt taacagataa ttcgagagga aaagattttt atgatctcta tactattcct
     7561 aaaatggaaa agatcgatga gaagaccttg aaagatagtg tgagaaatac atttacacgt
     7621 cgaggaaaaa ctgatccgtt aaagatttat tacgaaaagg atatggatgt actgaaaaat
     7681 agtcatgagc taaaagatac ctggaagaaa tatcaaaaaa gcaatcctta tgctgcgtcg
     7741 atcacgtacg aagagacaat ggattcgatt agtaatttga tggaaaaagt gattcacgtc
     7801 gaagaaaaag agcgaaaaat agcttatcaa agacaccaac agatgaacag agaaatggag
     7861 agataaaaat gatcaataat gtaactttag taggacggtt aaccaaagat ccagatttac
     7921 gttataccgc aagtggcaca gcagtggcta cttttaccct agccgttaat cgtaatttca
     7981 cgaatcaaaa cggcaatcga gaagctgatt ttatcaattg cgtgatttgg cgcaaaccag
     8041 cagaaacgat ggcgacatta gctaaaaaag gcatcttgat cggcgttgtc ggacggattc
     8101 aaacacggac ttatgacaac cagcaaggac aacgtgtgta tgtgacagaa gttgtagctg
     8161 ataacttcca actattagaa agcaaagcag cgacagagag ccgtgcgcac gctgatcaat
     8221 cgtccacgag tccaagcacc accacttttg aacaacggga tacagcgacg cctaacaaca
     8281 atggattgaa cgcttcacag aatccatttg gtggacaatc aatcgatatt agcgatgatg
     8341 atctaccgtt ttaagtagca ttttctattg gttgcatttg ctacggttta tgttataatt
     8401 tagtcaacaa aaagaatttt caatctataa ccaaaaacca ctagctggcg ggctagtggt
     8461 tttcttttac gtttctatta taagaattaa cgagtaggct tactgtcttt cttggcaaat
     8521 ttacaatcaa gccatttgca gatatagtgc gcggctactt ctgccatgat tgcaaaaaca
     8581 aaatcaaaaa gaattttcaa acctataacc tcctcccctt gccagattag gccggggtag
     8641 cagacagcaa gactattata gcataattga aatatccaaa tgattggatt tttgctataa
     8701 ttttagcgag gtgattgtga tgaacaaata tgttggtttg cttgataaaa tccgagtaat
     8761 aaaaacgcaa ccgttattgg ttcgctttac tttacaaacg attcatgaat cgattaattg
     8821 tgtagttgca gatattgaaa ttatcgataa attgctaatt atggatgatg gaaaatacaa
     8881 tattgccgtc acaggtcact tcaataaacg aaatcagctg gttattgcta gcatgtatgt
     8941 tagaaatccc gatcatttta cacgatcgat gggcatataa ataaaagaag agttgtagtc
     9001 ctaaatgagg attgcagctc tttttgtttt acatagaaac gggaacagga aaaggcctgt
     9061 ttaggaaggc acaagcgcct tctcaattaa aaaacctttc tctcactcca accgccaccg
     9121 ccgttcgaga agaaaggaag tgaacgctgc acgttcacta agatatggtg tcttgcaaag
     9181 caagacaaaa taggaaaagc ttcctctcac caaaaggttc gttcctgttc gctatctctt
     9241 tattgatttg ccagaccggc aacaagttgc cttttatcac caaaaagcga caaggacaag
     9301 ggtaaatggc acgctgcgcg cccttgtcct tgtcgctttt cgttgattca ttctggccaa
     9361 caaatcaata aagaaagaac taacgaaagg aagtaaaacc tttcctaaga ggaggcagaa
     9421 tcaatcatgc gaaagaaatt tgattattgg ggtgttccct tcagcgaatt attcccaaac
     9481 tatcatgcac cacatactgt cgaatgcgat tgtggagaaa gagcgaaatg tatcaaaagc
     9541 tatcgtttgt atcaatgtcc aacatgcggg aaaaaatata ccttgtctta tggcgattac
     9601 attttgattg atgagaaagg aaagaaacgc tgatgaaaac acaacacaaa ttattgaatg
     9661 taaaagaagt catttctgaa aaagtagcag aagctttact tattccgcgg tactggacga
     9721 tagaaacccc tttagtagag gacgcaccga ctatgctatt tgaagaccta gtgaagattg
     9781 caggatatga actgcattat caagaaaact tggaaactta tgaaaacgaa tattggttaa
     9841 ccaaattaga gaactaaaaa ggagaaaaaa tatggctcag aattactatg acgaatttgt
     9901 caaattacct ttggataaaa tggcacaaaa aatggaggat atgacgttcc tataccatga
     9961 aacacgtgta cccaaaaaac attacaagga aaaattgtca gtcgcagtgg aagaaatgat
    10021 tgaatcaggt gtcgaaatga atctcattgc gacgtactat cgaacattgg aagaactgaa
    10081 aaaacaaaat ggaaaatggt ttttccaagc cttactatgc ttggaagcag gcgtcaaacc
    10141 aagcacaatc aaaccttctg aataccaagc tttagaacta acgtatggaa aatttatcga
    10201 aacgaaaaaa gccaagactg tttcaagtga atggttggac tactttgaaa atgtcaacaa
    10261 gtatggcgca tgttacatca tgaaaaagga ggacaacgaa aatgagtaat gtggtttatc
    10321 aactaacagt ggaagatgtt tctcactttt taacaaacaa agaacatttg aatgaagtag
    10381 tcagacggat tcaaaaagac tttagttgta tggaagaaat gaagtacttt attcaaagag
    10441 tggaagaaca gttgtatatg gaaagcgaaa cgagtcaaac gaaggtcaca gtcagccata
    10501 atcatttaga cgtgtataaa cgtcgtcctg aaacggtaaa aaaaggaaca gagcttctac
    10561 gactagaaac agaaaaatac atcatgaatg tgtacctaga aaggagtgag ctggtcgaaa
    10621 actttgtcag ctacacgatt tgtaggaaac actattactc agaatcagaa tattattcaa
    10681 tttttgagag catggaatta atggaagaag aaatggaaga gctaaacagc aaaaatgcga
    10741 cggtagacga ttattacctt gtatttacta gatttctgac gtgtgggacg gaatctatcg
    10801 tgttaatggg aatggattat gaactcgctg tacccgaagc atttttgagg gaatatgtag
    10861 aagaagtaga taacccaggc gacgactggt acacgacttt aactgatttt ttagatacct
    10921 acacttacga cgatacagaa gaaatccaaa atgagcttga ctgtaaacga atgccatatc
    10981 aacgatttga aaggaaaaaa ggtcaataac catttatacc gaaaagtgag aatgtgtgaa
    11041 ataagaacaa aaaaccttga aattaaggga atggttctta tttcgcacca atcgctccaa
    11101 ccgcccccgc cgctcaggtg gtgcgaaata agcgggcaac gaccgataac ctaagagaaa
    11161 gaaggaaatc catatgaata aaatcattcc tctgttgttc gtactgtttg ttggcgagat
    11221 acttatgcgt catgctgcag ctgtacattt aaacttcgta gtattcttag gaatactggt
    11281 attttgtttg atcttttggc gatttgtatt agcccttgtg agtctactat tcaagatgat
    11341 tgcagccata tttttcatag ggttatttcg atgaaaggag agagtactaa tgccaattgc
    11401 aataggaaat aaacgtttac ccgtgacgtt ggatgaaaag agacaaaaag aattgcagga
    11461 actcaaacag aagtacggca aaagtgaatc caggattatg tgtattgcgt tagatttatt
    11521 gattgcacaa gaaaaagcag ggtttgatgt accagcactc aaaaagtgac gtcacttttc
    11581 atttgaagaa acaaaagtga tagcacttta cgcacgtgtc gatacgtgtt atgattattt
    11641 tgtaaggagg tatagtgcac aatgccactt acgggaaaag aaatgcttaa gttattgaaa
    11701 aaaaatggct gggttgagcg aaggcaagag ggatctcatc atcatcttta taaggatggt
    11761 gttagaatca ctgttcctgt tcatgccaat caagatcttg gccgaggact tgagcaaaaa
    11821 attttaaagg atgcgggatt gaaataatct cgcattcgat taaagaaagg attgactgaa
    11881 atgttaagtg agcctttagc aaaaacctat cctgctattt ttagcccaga agaaggtggt
    11941 gggtacttta ttgaatttcc tgatgttcaa ggtgcttaca caggaattaa cgaagacgat
    12001 atatcttatg gaattgctat ggcacaagag gtgttaggta tggttttagc agattatatt
    12061 gagcatgaag atctacttcc agaaccaaca ccaatcaata agatttctgt tgaagatgat
    12121 tcttttacta ctttaattcg tgtagatgtt gccaaatatt tgaaagacac agaacttgtc
    12181 aaaaaaacct taacaattcc tcaatgggcg gataagctag gcaaaagggc tggcataaat
    12241 ttttcagtcc ttctaacaga atcaattgca gataaagcag ataaccttct tcgttctgga
    12301 agaaataatt agaactcaaa agagtcagaa acttaaaaat ctttggcttc tttttttact
    12361 acaaagatgg cttctttaaa ttatttgcct gattgattta aaaaaattgc gcaaagacta
    12421 cgagctaatt aagttgctcg tggtctttct ttatgaaaac tttttagatc tagataaaaa
    12481 cattgagaca ctttgaaaaa tttttttaat agtaatgggc gcttctatgt caagctgatt
    12541 cttctttcgg taaattaatt ttacttagaa tatcactatc ttgataaaaa atggtgtatt
    12601 cacaaattct ggcataaaaa atacctactt tctagttaag gttcctgaat aagtcgcaat
    12661 ccaattattt ccagctgatt tataactttt taaatataat tttccataat accaataacc
    12721 attacttttt tctgtccaat ttcgttattg agaagatcta gaaggccagc caactttatc
    12781 aaaaatcatc attcctgtca ctcgtatcgt tttagaagct gctcgagtaa gtaatggaga
    12841 aactgttaaa taattttaag taacagttaa gtcgttagtt gggttatcaa tggctattcc
    12901 gtccttatct gaacctcgaa acccaatcat agaaaaagtt ttttgaacaa gttttaacag
    12961 ataaatcaag ttatatacta gaaaattcgt aaaatatatt tttaatgtca taatcgtttg
    13021 atttttctgg attgacattt atttataaaa aatagtgcca ttaaaaaaga aaagtgacac
    13081 accaataaaa gtcatatcct gtgacattat atggcattat ccaaatagaa taaccggttg
    13141 acatgtaagc ggattccttt tataatttta ggagtataag tccttttcta aaaatattaa
    13201 ccggttatca tgaaagggga tacaaatata tcgttggagg ataaaaatat gtcaaaggtt
    13261 aacgtattta aaaatcaatc ctatttacaa agttcagcta cattattact attttttgct
    13321 tcttggggtg tttggtggtc attttttcaa ctttggctaa catctgaatc aaatggttta
    13381 gggttatctg gcagtgctgt aggaacagta ttctcggcaa attcgttagt taccttaatt
    13441 ttgatgttta tttatggaac attacaagat aaattgtata ttaaacgaaa tttattaatt
    13501 tttgcttctg tattagcgac acttgttgga ccatttttta tatggatata cgggccattg
    13561 ctagataaca attttaattt aggcattatt atgggagcac tatttttgtc agctggatat
    13621 ttagcttctg taggagtttt tgaagctgtg tcagaaaggt ttagtcgttt atttggcttt
    13681 gaatatggac aagcaagggc gtggggatca tttggttatg ccttggtagc gcttttggca
    13741 ggatttttat ttgtaaaaaa tcctcattta aacttttggg cgggatcttt ctttggttct
    13801 ttactattgt taaatttatt attttggaac cctaaagttg aacgggaagc aaatcaaaat
    13861 tttaatcaag aacaagctga atcaaatagt attccttctt taaaagaaat gtttgatcta
    13921 atgaaactgc ctcaattatg gacgataatc atctttattg tttttacatg gacattttat
    13981 acggtattcg atcaacaaat gtttccggga ttttatactg gtttgttttc aacatcagct
    14041 aatggtgaaa aaatatatgg gacattgaat gctattcaag tattttgtga agcgttaatg
    14101 atgggaattg ttccaatcat tatgagaaaa ttaggggttc gaaatacttt gttattagct
    14161 gtaaccatta tgtgtgtacg aattggattg tgcgggtttg cctcgacacc attatctgtt
    14221 tcatgcataa aaatgttgca tgctttagaa gtaccattat ttacattacc aatgtttcgc
    14281 tattttacac ttcattttga tacaaagcta tcagcaaccc tctatatgat aggatttcag
    14341 atagctgctc aaattgggca agtgatttta tcaacaccat tgggaatatt aagagacaac
    14401 gttggctatc aaccaacatt taaaattatt tctcttattg tattactagc aggcatatat
    14461 gcattcttta ttcttaaaca agatgataga gatgttcaag gggatccatt tattcgagga
    14521 taatggaaac caacagaata aaaaacaatt ttatctagaa agtgagcgaa tatattatga
    14581 caaaaagagc tatagaatta acaaatacac gttatcgttt gggatatcat gtgtctgcac
    14641 catcaggatg gattaatgat ccaaatggat tttgctattt tgatgggtat tatcatgtgt
    14701 tttatcaaca tcatccatat agtgctgaat ggggaccaat gcactgggca catgctagaa
    14761 gtaaggattt agttcattgg gaatctttac cacttgcttt gactcctgaa gatcaagaag
    14821 atgaaggtgg ttgtttttca ggaagcgcta ttgaaaaaaa tggtgtgttg tatctgttct
    14881 atacaggaca tcactattat ggagacaatg atccagatca tttttggcaa aatcaaaaca
    14941 tggcgtatag tacggatggc attcacttta ctaaatatga aaaaaatcct gtaatagcaa
    15001 aagcaccaga agataacaca catcatttca gagatccaaa agtatggaaa cacgatgaaa
    15061 aatattacat ggttttgggt agtcaagaaa aagatggatt aggtcgtgct attgtttatc
    15121 agtcgttaga tttattaaat tgggattaca ttggaccaat ttctaaagcg aaggaagtac
    15181 ttacagaagg atttatgtgg gaatgcccag acttttttga attaaatgga aaatctattc
    15241 ttttattatc ccctcaggga attgaagcaa atggaaaaga ttatttaaat ctatatgaaa
    15301 caggctactt tatcggtgat tatgattatg agacagcaaa attcattaga ggaaattttt
    15361 atgaattaga taagggacac gatttctatg caacacaaac aactttatct ccagatggta
    15421 gacgtattgt tatggcttgg atggatatgt gggaaagccc tatgcctgaa aaagtagacg
    15481 gatgggcagg agcattaacg cttcctcgag aattagagtt aattggagat catttgtata
    15541 tgaaacctgt gagagaatta gaacaacttc gagttggcag cggcgttgaa acaaaagtta
    15601 atttggcagg agaaataata atcgctcaag atgcttcatt caaagaagct ctaattgatg
    15661 tactattgac taaatcaaaa aatcaagaaa tcaaattttc attaaaaaca aaagatgaag
    15721 agttaattaa tattttttat tctaaggata aaaatgaatg taccttaact cgtaacggca
    15781 aaaatgatcc aaggtatgga accattcaga tgtgtgatag attatcactt cgagtgttta
    15841 tcgataaaag ttcggcagag atttttatta atgatggcga gcttgttttt acagagcgtt
    15901 attatacaga aaatcaacca agtatgcatt tgagtgttag tgaagaagct tttgtctcga
    15961 gtacaattta tcatctaaaa aaagatgcaa tttcttacga gtaaggaggt tttatgatgt
    16021 taattggtag catagaagca ggtgggacta aatttgtatg tgccgtggga gacgaggatt
    16081 accgagtaca agaccaaata atttgtccaa cgaccacccc cagggaaaca ttgaaaaaaa
    16141 ctgttgacta ttttaaacag tttgatataa atgcattagg tattgcatca tttggtccaa
    16201 tagaaattcg aaaaaattca ccaaaatcag gatatattac gtctacacca aaggtgggat
    16261 ggcgaaatgt taatgtgtta ggttatttac aagatgagct gaatgttcca atgtcttgga
    16321 caacggatgt gaacggatca gcttatggag agtacatcat gtccacttta tcgaatgaaa
    16381 aaataaattc attagtttat tacaccgttg gtactggcgt tggtggtgga gctgttgttg
    16441 acggaaaact attaggatcg tttggtcatt cagaaatggg ccatacgttt gtaaaacgcc
    16501 atcctgatga tattgatttt aaaggaattt gtccttatca tggtgattgt ttagaaggct
    16561 tagttgcggg accaacgttt gaagcacgtt ttggaaaaaa gggtgaagac gtttctttaa
    16621 cggatcctat ttgggatgta atggcctatt atctagcaca agctgtgatt caaacaacat
    16681 tgattatacg accggataaa atagtatttg gtggaagcgt agtaaatgaa aaattgttag
    16741 aaaaaattcg tgttaatgtt aatgaattat tggatgatta cgtggaaata ccaccgttaa
    16801 gtaaatatat tacgcgtcct ttaattaaaa ataatggatc ggcaacacta ggaaactttg
    16861 ctttgggctt gaatcaatta caagaataaa acatagaaaa aatatcgatt atcaggtata
    16921 gtagttctat agagttcttt ttttcgatag ttaattattg cattatttag gagagacaag
    16981 agaatgcgcc caaaattaga agatgttgcc aaaagagcaa atgtatcaaa aacaactgtt
    17041 tcacgtgtat taaacaatcg tggctattta agtcaaaaaa cgattgataa tgtttataag
    17101 gctatagaag aactcaatta tcaaccgaac gttgtagcgc gtcaattatt tcaaaagaaa
    17161 actaacattg tcgggttact atttcctaca gtagccaatc ctttttttag tgaactcgtt
    17221 gaggcattgg aaaaaaagtt atatgaaatt ggttataagg tattaatagg caattcgatg
    17281 aataataaag aaaaggaaac aaattattta aatcagttat tgtctgatca agtagatggt
    17341 ttaattgttg gtacacataa ccaagggatt caggaatata aatatcagaa tttaccgatt
    17401 gttgcaattg atcgagtgat gaatgaagat attccagttg ttgaatccga taactacaat
    17461 ggtggaaaac ttgcaaccaa gttattaatt gcacaaggtg caaaaaatat tattcataca
    17521 aacggtccaa ttgacttaca gactccggct aatcgtcgga gactagccta tgaagatact
    17581 atgaaagcat atcagttaat tccacgaact gtgacattag atttcaatat ttcttatgta
    17641 aagaaaaaac agattttttt ccaaatgttt gaggattatc ctaaaataga tggtattttt
    17701 gcttcaaatg acatcgatgc ggccctaata ttacaagtag caaaagaaaa ggggttaaat
    17761 gtaccagctg atttattagt agtcggatat gatggtactt taatgactcg gagtatatta
    17821 ccagatctga caacagtaat acaaccaatt aatgatatag cagacacagc tgttgctatt
    17881 ttgatgaaac gaataaataa agaagaaaca aaaaaggaat atattttacc tgtcacatta
    17941 tggatgggga agacatcagt aaagaaaaag gacaattaaa tttataaaga ctatcaatga
    18001 ta
//
LOCUS       DAIGTA010000057        17797 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.060, whole genome shotgun sequence.
ACCESSION   DAIGTA010000057 DAIGTA010000000
VERSION     DAIGTA010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.060"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(4..1305)
                     /locus_tag="NOB43_002122"
     CDS             complement(4..1305)
                     /locus_tag="NOB43_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI0982966.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(1535..3493)
                     /locus_tag="NOB43_002123"
     CDS             complement(1535..3493)
                     /locus_tag="NOB43_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HCI0982967.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(3670..3936)
                     /locus_tag="NOB43_002124"
     CDS             complement(3670..3936)
                     /locus_tag="NOB43_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0982968.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(4446..6572)
                     /gene="pnp"
                     /locus_tag="NOB43_002125"
     CDS             complement(4446..6572)
                     /gene="pnp"
                     /locus_tag="NOB43_002125"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCI0982969.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(6760..7029)
                     /gene="rpsO"
                     /locus_tag="NOB43_002126"
     CDS             complement(6760..7029)
                     /gene="rpsO"
                     /locus_tag="NOB43_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCI0982970.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            7280..7843
                     /locus_tag="NOB43_002127"
     CDS             7280..7843
                     /locus_tag="NOB43_002127"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI0982971.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHTKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(8096..8617)
                     /locus_tag="NOB43_002128"
     CDS             complement(8096..8617)
                     /locus_tag="NOB43_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HCI0982972.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(8620..9462)
                     /locus_tag="NOB43_002129"
     CDS             complement(8620..9462)
                     /locus_tag="NOB43_002129"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCI0982973.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(9455..10180)
                     /locus_tag="NOB43_002130"
     CDS             complement(9455..10180)
                     /locus_tag="NOB43_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCI0982974.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            10356..10652
                     /locus_tag="NOB43_002131"
     CDS             10356..10652
                     /locus_tag="NOB43_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982975.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            11220..12812
                     /locus_tag="NOB43_002132"
     CDS             11220..12812
                     /locus_tag="NOB43_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0982976.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            12825..13565
                     /locus_tag="NOB43_002133"
     CDS             12825..13565
                     /locus_tag="NOB43_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0982977.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            13733..15082
                     /locus_tag="NOB43_002134"
     CDS             13733..15082
                     /locus_tag="NOB43_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0982978.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(15210..15800)
                     /locus_tag="NOB43_002135"
     CDS             complement(15210..15800)
                     /locus_tag="NOB43_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI0982979.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            15947..17299
                     /gene="brnQ"
                     /locus_tag="NOB43_002136"
     CDS             15947..17299
                     /gene="brnQ"
                     /locus_tag="NOB43_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI0982980.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         5118 a         3603 c         3405 g         5671 t
ORIGIN      
        1 cttttattct atttttcttt ccgtggactc tactttgaaa taatcgatat gtgcatgctg
       61 gtattctaat accgtgaaac ggaatgatgc aatctcaatg attgttcctg cttttatttc
      121 tttatatcgg ctagaagcaa agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg
      181 aatctctaca tgaaaataac gctggaaatc atctaatgtt agtttgccgg agatgatata
      241 agagccatct gactgttccg ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc
      301 cccgacgatt tcttctaaaa tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc
      361 atcttttaag atagcaatat gctttccctt ttttcgcatg atcgtcaata atttttttat
      421 agggatcgtt tcagttgtta cgatcggctc ttcaatcaac tgttctactg tcagctggtc
      481 atctttataa gattgcttga tcaaatctgg caaggtgaca taacctaaaa cattgtcttt
      541 tgattctaag ataaccggat agcgagtatg tccttgttca atcgaagctt ttatcgcttc
      601 tttgacggtt tctgaagctt cgaatacttg catggacgta cggtctactt gtatatcttt
      661 tgccaaggta tcatcaaatt caaacacgtt ttccaaataa tgatattctt ctttggtcaa
      721 ctctcctttt tcataagaat tcaatgcgac taatgtcagc tcttcttgag acaatgtctc
      781 ttctccttca gatacgagac gcacacctaa tagcttccct agccctgcag ctgaatgatt
      841 caatacccaa ataaaaggaa acattacttt ataaaaataa tgaagtggtt taactacgaa
      901 caagacgacc ttctccgtat tgacgatact atagctctta ggaagcagtt cgccaataac
      961 cacatcgata tacgtaacta aaataaatcc cagcgccaca gagattgtac tgctaatagc
     1021 cgaactaaaa ggtagtttac cgatcactgg ttctagtaaa gccgcgacag atccttcacc
     1081 gacccacccg atgatcaaac cggttagcgt aattcctaat tgactagctg ataaatagtt
     1141 atctaaatgg tgtgtaacat gaagagctag cttggcgttc tttacatttt ccttttctag
     1201 ttgttccaat cttgatcgtc tgattttcac taaagcaaat tcacttgcta caaaaaatga
     1261 agtaattgca atcatcaaaa ataaaataat gaaattgata accatattct cccgcctttc
     1321 tctttttcta ttgtaccctt tttctacaaa aagattgaaa ataatgcgta ttcatattta
     1381 ggaataaaaa aggagatgcg gcatttttca gccacatctc cttatcactt caaaatcatt
     1441 gcgttacttg ttgctaaaca gctttttcat gacctctgat aaacggtgtt caagtagctg
     1501 acattcgaca ttagttcagg tcaaagcgct actttcacaa ccgctctttc aaccatgttt
     1561 tccgagtatt tccaatgata agcggaacag tttcatgttt tacttcgctg tactctagcc
     1621 caaaccatgt ttctggcgag gtagcgattt ttttgattgc cagttttgcc tgcatgattt
     1681 gacgttgcca ttttcctaga gttgtcacat tggaaactac ttcatcaatc aggacaaatt
     1741 ggaaatcgcc aacttctcgc cctggtgtca gagagtatct ttgtggctgt tttggcaaac
     1801 ggccttgttt catcaaatca tggatgactt ggcgaacata tacgttgatt tcctgttgga
     1861 ccctgaaacc taagaacaga ttcacttgga caataaaatc agtgtccatc atatctactt
     1921 gatattcttt cgtatatggc tcatccgtca cttccacatg aacaaaccaa tagactcgtg
     1981 ctcttttagg ccgtttatct aaaatcgaat agatgaactg tcggccaact ttatcttcag
     2041 ccatatcagg aaccaagaag accacatttg tctgatagat tggtaaagaa gtatcatcac
     2101 gtaattctct aagctgcggg atataatctc tcaaagacac atcctcggtt gacgattcgc
     2161 gaataatgtt cccttgttcc caaataaaca tcacgactaa gatgatcaaa ccaatcagaa
     2221 cggctacaaa accgcctcgg aagaatttga caacacttga gataaagaaa acgacttcta
     2281 tcgcaccgaa gaaaaaggta actaaatatg caagccaacg agaatgccca ttttggataa
     2341 gataaaagta aagcagtgct gttgtcatca acatcgtcac agtgatcgat agaccgtaag
     2401 cagcttccat atgatgagac gttcggaatg tgacaaccac tagagaacag gcgatccata
     2461 aaatcagatt gactgctggg atatacattt gcccgatact gttcccagga tacatgatct
     2521 ttaaccgagg cagcagtttc aacttgattg cttctgaaac tagcgtaaac gaacctgtaa
     2581 tcaatgcttg cgaagcaatg actgcagcga ctgttgcaaa agcaacgccg atcacgatcc
     2641 aactttgagg catcatttgg aagaatggat tcaggttctt gatttgctgt gcttcagggt
     2701 tttgataaac attcaacaac cacgcagcct gcccaaaata attgataacc aaacaaattt
     2761 tgacgtaagg ccagctcaga cgaatatttc gtttgccgac atgtccaaga tcggaataaa
     2821 gcgcctctgc acctgtcgta gccaggaaaa tatttccaag aatgaacaag cctaatttgt
     2881 tatctgcact aaaaagcagc tggatagcat aataaggatt cagtgcacgg ataactgtcc
     2941 agtcttgact gaagttcatt aatcccatta cgcctaaaaa agtaaaccaa gcgaacatga
     3001 ttggtccgaa tgcttttccg acaatatctg taccaaagcg ttggaccatg aataaaacaa
     3061 aaataataac taaagtgata atgacgatca cgttctggtt attaccgaac cggtcaaaaa
     3121 actgcggaat tcctcgcaag ccttcaatcg cagtcgttac cgtcacagca ggggtcaata
     3181 ccccatctgc tagtaaggca gctcctccga tcattgcagg aatgatcaaa tatttcccac
     3241 cttttcggac aagtgtgtag agtgagaaaa ttccaccttc accatggtta tctgcattca
     3301 atgcaatcac gacatatttg attgttgtca gtagagtcaa tgtccaaaaa atcaatgaga
     3361 ctgatccgat aacaaaatca ggattgattc ctgacaatcc gccattatct tcaacaatcg
     3421 atttcataac gtaaagcgga cttgtcccga tgtctccgta gacgactccc atcgctacaa
     3481 gcaggccagc cattgatatc tttttggtat tgtgcgttgt tgccacgttt ttccctcatt
     3541 tcttgttata tggatatcct ttaggtaagc ttgaatgata gatgatattc ttatccatga
     3601 cacccgcttt cctaaattgc ttctaattat ccaagtaaca cactgaagtg tcaacttatt
     3661 tgaataaaat tattctttct ttggacgttc tctgatacgt cttgccacaa atgaataaag
     3721 agcaaggcaa aaaattgcac ccaataatgc tggtatcaaa taaaaaccgc cgagttccgg
     3781 tcccagtggt cctagtaaaa attcgccgag ccaactacct aaaaaaccga taatgatatt
     3841 tccagatacg cctcccggga cttcctttcc taaaattgcg ccagctatca aacctaatat
     3901 accgccgata aataacgacc ataaaaaatt cagcatctcc tttccctcct ttatccatat
     3961 ttctcacttt tattttacgc tttattcaga aggactccaa aaatatgcgc caagaaactc
     4021 cagaaaaaaa gaagttgtaa caaaagtgtt cagcttattt ccgtagaagc tgcttctgga
     4081 acaccgtgaa tcagaggttg tgaaatcagc ggtttgacct gagtattaga gaaacaaacg
     4141 gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat atcgagggac agctgattga
     4201 acatcgttta ttggagaggt tgtaaaaaag ctgttctgca tcaagtaata agaacagcca
     4261 agtaaaaaca gctcctaatg tttttaactt ggctggactt attaccgcag atgcaagctt
     4321 ttgaacaccg tttattcgaa aaaaaaggac tgtgacacgg cttttgtcac agtccccttt
     4381 tttcgaataa ttattgtccc cctgtcacct tcacgatcac aagtacatta ttcctatgaa
     4441 ttaaattatt tttcttcatt tttcgttgaa ccatcttcgt tcaacattgc ttttcttgac
     4501 agatttacgc gtccttgttt atcgatttca gttactttca caaggatctc atcacctagt
     4561 ttaacaacat cttcgacttt attgacacga tcgtttgcta attgggaaat atggacaagt
     4621 ccatcttttc ctttgatcaa gttgacgaat gcaccgaatt tttcgatacg gacaactttc
     4681 cctagataaa cttcaccaac tttgacttct ttggtcaaat cttcgatgat cttgatagct
     4741 tttttgatca tttctgcatc agctgaagca atacttactt ttccatcttg atcgatatcg
     4801 attttcacac cagtttcatc gatgattccg ttgatcgtat cgccgccttt accgataaca
     4861 tctttgattt tagcaggttc gatctggatc atttcgattt ttggtgcata ttggcttaat
     4921 tcttcacgtg gagcagcaat cgttgaagtc aattcttcta agatttccat acgtgcttgt
     4981 tttgcttgag ttaatgcttc agttaggatt tgttctgtga ttccttgaat cttgatatcc
     5041 atctgtaaag cagtgatacc atcttttgta ccggcaactt taaagtccat atcgccaaga
     5101 tgatcttcca gcccttggat atcagttagg atcgtatagt tttcaccatc agaaacaagt
     5161 cccatcgcaa taccggcgac tggcgctttg attggtacac ctgcatccat caatgctaat
     5221 gtgccagcac agatacttgc ttgggaagaa gaaccatttg attccaatac ttctgctact
     5281 aaacggatcg tataaggaaa ttcttcttct gaagggatta cttgtgctaa cgcacgttca
     5341 cctaatgcgc catgtccgat ttcccgacgc cctggagagc ctgcacgtcc tgtagaacca
     5401 acagaaaatt gagggaaatt gtagtggtgg atgaatcgtt tgctgacttc cacccctaaa
     5461 ccatcaatga tttggtgctc tcctagaggt gcgagtgtac aagctgataa agcttgtgtt
     5521 tgtcctcgtg tgaacaaacc tgatccatgt acacgtggca ataagctgac ctctgatgac
     5581 aatggacgga tttcatccaa tttacgcccg tcaggacgga tcttatcgat ggtgatcaat
     5641 tcacgtacga catctttttc aagatcttct gtgatttgtt taacttcttt caacaagtga
     5701 tcttcatctt catgacctgc aaatttctca gcataagctt cgcggatatc gatcttcacc
     5761 tgctcgatat tatcttcgcg agcaagtttt tcttcagtca ttactgctgc tttcattgta
     5821 gcgtaagaag catcaaagat ttcttttttc aatacttcat caacttgcag taaagtcact
     5881 tccatttttt ctttccctac tgcttgaacg atttcttctt ggaaagcaac taactctttg
     5941 atagcgtcaa aaccaaacag caatgcacca agcatgtctt cttctgaaac ttctttcgcg
     6001 ccgctttcaa ccatattgat ggcttgtttc gttccggcaa cagtcaattc gatatctgtt
     6061 tgttctgctt gttctactgt tggattcaag acgtactcgc catttacacg accaacttct
     6121 acgcctgcga ttgggccgtc aaatgggata tctgagattg atagtgctaa agaagaacct
     6181 agcattgctg ccatagctgg cgagcagtct gtttctacac tcatcacgat gttcgttact
     6241 tggacttcat tacggaagcc ttctgcaaac atcgggcgaa ttggacggtc gatcaaacgg
     6301 gcagtcaatg ttgcttccgt acttggacgg ccttctcgtt tgatgaaacc tccagggatt
     6361 ttccctgctg catacatttt ttcttcataa ttgatcgtta atgggaaaaa gtctgtatct
     6421 tttgcttctt tagaggccac agctgcactt aagactactg tatctccata acggactaaa
     6481 acggctccgt ttgcttgttt tgctagctga ccgacttcga tttgtaaggg acggccgccc
     6541 catgtcgttt tgaatacttg tttttctgac ataacttctc cttttccttc tcgtgaaagc
     6601 aagacgctac taaacaaatg aaaactgccg aaagccgtct tttgagcagc tttcatttgg
     6661 ttagtaggag tccatctagc ttgatcacgg aattttactt aattgatata cgagtaaaaa
     6721 aagtgagatt catgtgaatc ccactctttt tgactaaaat taacgacgca agcctaaacg
     6781 tttgatcaat tcgcggtaac gttgaacgtc agttttacgt aagtaagcta acaagttacg
     6841 gcggtgacca acttttttca ttaggccgcg gtatgaatga tggtcttttt tgtgcacgcg
     6901 tgcatgttca ttcaagtggt tgatttcttc agttaataca gcgatttgta cttctggaga
     6961 accagtatcc ccttcatggc gagcgtattc gttgatgatt tcattcttgc gttcttttga
     7021 aattgccatt tctttcacct ctttcgatta ttcccctgcg actgagtaaa acgttggtga
     7081 ttcgcttaac caagtggcag gtcatgtgcc tagagcacac agctatactt tacctgaaac
     7141 cgggttgaaa atcaagtagt taatcattaa gaaaaggtag ttttcaaaca atcttactac
     7201 tacttttcca tttttgtggt aaactataat gcgaaaatag acttgaaaca cagtctttta
     7261 agaaaggggt acatattcca tgattacaat ggatgatatc attcgtgaag gaaatccgac
     7321 cttacgcgaa gttgcaaaag aagtttctct tccattaagc gaagaagata tctctttagg
     7381 aaaagagatg cttgagttct taaaaaacag ccaagatcca atcaaagctg aagaactaca
     7441 cttacgaggc ggtgttggct tagctgctcc tcaattagat atttctaaaa gaatcattgc
     7501 tgttcacgta ccaagtcctg acccagaggc agatggacct tctctaagta ctgttatgta
     7561 taatcctaaa attttgagcc attctgttca agatgcttgt ttaggggaag gtgaaggctg
     7621 tttatctgtt gatcgagaag taccaggata tgttgttcgc cataccaaaa tcactgtgtc
     7681 ttattatgat atgaatggtg aaaaacacaa gattcgtttg aagaattatg aatcgatcgt
     7741 cgttcaacat gaaatcgacc atatcaacgg tgtgatgttc tatgaccaca tcaacgatca
     7801 aaatccattt gcactaaaag aaggcgtatt ggtgatcgag tagagaattg gcaggttcct
     7861 tcgatactat gctacaagaa agctttataa aaaaggggag tgctcaaaag ctgcacttcc
     7921 cttttttatg tttctccact aatcgaaatt tagatagaca tctagaaatc gcaattccaa
     7981 aaaattctgt gtattggata cgcatctttt cttatttttt cttatttctt ccatatgggt
     8041 gtttatctca gagatgatag aatagtttct aggataaaaa gtagcagcta cgatgttatc
     8101 cttcgtagag gattcctgct tcagctagtt tttgtttgat gtttttcagc atatgctttt
     8161 ctgggtagcg gatcgtatgc agatggatgc cgcctgttaa ttcggataac aaagtagcat
     8221 tacttttttg ataacgtctc ataaaggaat cgatatcttg tggcgttttg atgtgcaaag
     8281 ttcctgctaa ctcaccgtaa aggggatgtt ccacaattac atcaatgatt tcaccaccat
     8341 tttcaacgat tagtctcagt tcttcttctg tttgatcttt tccatgctgg acagcgattt
     8401 tactgatgtg cccagtattg gtttcttctg tttcgaggat ataacctctt gctgttgcca
     8461 cgatactttt acctgcagct cgtagtaaag caatatcgcc tacaatgatc tgacggctga
     8521 ctccaaaagt tttcgcaaac ttgctagcac tcactggttt ttctgtattt gccaaggttt
     8581 gcatgatttg ttttcgccgt gtctctcctt cgatcacact tattcctcct tcattttgtt
     8641 ttggtattcg cgcgagtgtt tcatcaaatc aacatacgtg tctgttattg tttccttata
     8701 tcccttattt ttcagcagac taacaacttt atccaatact tgctgctctc tttttgcatc
     8761 ataaactgct tggttttctt cttttttcac ttgtcctatt ttagttaccg tatccattct
     8821 tttttctaat aaagcaacca actctcgatc gatcatatcg atcttatgac gtaatgtttc
     8881 aagagactct tctgttagtt cttcctctac tgtcttgatg atacgagcag gatttcctgc
     8941 aatcactaca ttgtcgggaa aagatttggt cacaaccgaa cctgcgccga ctactacgtt
     9001 gtcccctaga gtgacacccg gcgtgacgat aactcctccg cctaaccaaa cattattacc
     9061 gattttaatg ggttttgcgt actccagacc gctgttacgt ttcactggat gtagtggatg
     9121 cgtcgccgtg taaagctgga cattcggagc gaacatgcag ttatcaccga tttcaatcgt
     9181 gctgacatct aaaaatgtac aattgaaatt tgcataaaaa ttctccccaa caaatatatt
     9241 atatccgtaa tcaaaattga taactggctc catatagatt tttttccctg tacggccaaa
     9301 agtctctttc aacaattggg atcgcagttc cgctgattct gcttggttga tgatttggct
     9361 ttgacttctt gcaaacatac ggtcggcaac cagctcagga tcattggcaa aataaagctc
     9421 gcctgcaatc attttttctt tttcggtttt gaattcagtc ataatctgct cctaattctt
     9481 gtattttttt gaaaacaacc gctccgtctt cttgaataaa cgtataaggc tccgctaaat
     9541 aaacaggcgt ttgattgatt actaagattt tggctgacgg ctggcgaaac tgtaccagat
     9601 cacaaaacgg atgaacttga aaactcgttc caacaatgac gatcagctct gcttggctga
     9661 cggcataagc cgcctgctcc atgactccat cttgaaaccc ttcaccatat aacacgatgt
     9721 ctgggcgtat ttgtcctccg catgcttgat gtttgtcgct gtgaagatat tctttccagt
     9781 ctaccgtttg ttgacatttt cgacaatgac attgatacag actcccatga aaattgacga
     9841 gttgcgggct tttagccttt gcgtgcaaac cgtcgatgtt ttgggaaaca acccaaacat
     9901 ttttttcttt cgctagatgt gctatttcca aatgaatgat attgggtttt gcttcaggat
     9961 gataaatctt tttgacaaat tgatagaatt tatccggttc attcaccatt gcttgatgac
    10021 tcagcaagta ttccggctgc tccatcccgt ggtagattcc tgacaaagat cgatagtctg
    10081 gcactccaga aggtgtggat acccctgcac cggtcaaaaa tgtaatttgc tgataagcta
    10141 atatctcttt tgctgcttcg tctactgtta attgtttcat gttttgtcac ctcactttcc
    10201 attatagccc atactcgaac aaatttattg ttgaaaagtc agaaaaatgg gaataaaaaa
    10261 gtgttatggg catttgagca atttatcaca atgttcactg acaaaagaat gaaaacgtgt
    10321 tacaatactg ctgtataaaa gtgaggtgaa tcgatatgtt accattcttt atttattggg
    10381 gcgttattct ggcttgtatc gcctggttag cgttaagcgt ttatttctct gttttttatc
    10441 ttgtacgcaa agaaaatgga aatctttggg cttttgcttt attcaacgtg attgccgcaa
    10501 ttgttttagc cattacatta gccgtatatc gaacatgggg ctggggaatc acccaatact
    10561 caagtttgat ttatctaata ttagccattt atggcgtcgt tgttcttttg caagcgatcc
    10621 taggacgtga gccaaagaaa gcggcagctt aaatgatcga gatggaactg gacacaggaa
    10681 attttctgtt ctagttcttt ttttattgta ttacatacat ttttgtgtat aattatacta
    10741 tcgtttgcaa tggatagatg attcacattt tgattgtttt ttcggtaaaa gtaaagattt
    10801 ctatatttat cagtattttt tcaaaaacca gcagttatag attgacaaag cctctcgagt
    10861 atcgtaaact ttttttgtat aaataactga atacgagatg cctcaatcaa tgaggtagag
    10921 gtcgcgagaa tcattaaccc tgtggagtga agcaaacatg gagaagcagg aatagggagg
    10981 atcgccgaaa tgtgcacttt tttgcttgga gtgtatgttg ggacgcaagt taagagcttg
    11041 cggactgtct tagcagtgat gctaagttgc gctatgtttt gtgagaggtt tatcacctta
    11101 tggaatttta gcggcctttt tatatctata aatcggtcgc tttttatttt ttcagataaa
    11161 gctttaccgc atttcatcta gaccgctcgt gtatcatata atcagaaagg gagaaaaaaa
    11221 tgaaaaaaaa tatggtttca gttgccgtac tatttgcttt tgtcttctca ctattcagtg
    11281 tgggatctct ggcaaatgca gatgaaaaaa caccgagcga tgagtttcgc gtaggtatgg
    11341 aggctgggta tgcacccttc aactggtctc aacaaacaga tgagaataat gccttgccaa
    11401 ttcaaggcca aaatagttac gccggcggtt atgatgttca aatcgctaaa aaagtagcag
    11461 atggtttagg gaaaaaatta gtcatcgtcc aaacgaaatg ggatggtctg gctcctgccc
    11521 ttcaatcagg caagatcgac gcgatcatcg ccggaatgag ccctactgct gaacgacgaa
    11581 aagaaattga ttttaccgat ccttattacg aatcacaatt agtagtagta gttcaaaaag
    11641 atagcaaata tgcaaaagca aaaagtttag cagatctttc tggagcaaag atcactgctc
    11701 agttaaatac attccactat actgtgatcg atcagatacc agatgtgcag aaacaacaag
    11761 caatggataa tttctcagca atgagaacag ctttagcttc tggaatgatc gatggttatg
    11821 tcagcgaacg tccggaaggt gtaacggcaa ctagtgtgaa caaagacttg gaaatgcttg
    11881 aattcagcgg tgcagatggc ttccagacaa acccggaaga tgttcagatt tctgttggta
    11941 tgcgtaaagg cgacccggat atccaaaaag taaaccagat tctttctggc atctctaacg
    12001 atgaacgaac caaaattatg gaccaagcag tcaaagatca gcctgctgca actgatagtg
    12061 aagaaaaacc tggcatcatt tctgatttca ctacgatttg gaaacaatac ggcaatatgt
    12121 tcttacgagg tgctggactt accttgttca tcgcattgat cgggacagtt gtcggtacta
    12181 cacttggatt actgattggt gtcttccgtt cggtacctga atcaggaaat gcactgactc
    12241 gcttcttcca aaaaatcgga aatgcacttc tttctatcta tgtcgaagta ttccgcggaa
    12301 caccgatgat ggtacaagca atggtcatct tctacggtct ggcactcgct tttggcattt
    12361 cattgaaccg aacgattgcc gctttgttta ttgtctctct caatactgga gcttacatga
    12421 cagagatcgt tcgtgggggg atttttgcag tagatgaagg gcagttcgaa gctgcgcaag
    12481 ccattggtat gacccatggc caaacgatga gaaaagttgt tattccacaa gttttacgga
    12541 atatcttgcc agcaacagga aatgagtttg ttatcaatat caaagataca gcagttttaa
    12601 gtgtaatcgg cgtagctgat ttgttcttcc aaggaaactc tgcttccggt gcgaatttcc
    12661 aattcttcca aacatttacg atcgtcggga tcatctactt agtcatgacc tttacgatca
    12721 ccagaatcct gcgggcggta gaaaagaaaa tcgatggtcc ttcagcttat accaagcttg
    12781 aagaaatcga caattcaaat ttgcaggaat aaggaggaag aatcatgaat gaaaaaatta
    12841 ttgaaatcaa acatctaaga aaaagcttcg gtgaaaatga agtattgaaa gatatcagcg
    12901 taacagtcaa taaaggtgaa gttgtgacga tcatcggttc ttccggttct ggtaaatcta
    12961 ctttcttgcg ctgtatcaat ttactggaaa aaccaacagg cggcgagatc atttataatg
    13021 gagaaaatgt attagctcct aaatataatt tacctaaata tcgaacgaat ctaggtatgg
    13081 ttttccaatc cttcaacctg ttcaacaata tgaatgtctt ggaaaactgt atgtctggtc
    13141 aaacaactgt cctgaaacga gataaagaaa ctgccaaaaa agtagcaatc gaaaatctgg
    13201 aaaaagttgg tatggatcgt tatatcgaag ccaaaccagc acaattatct ggtggacaga
    13261 aacagcgtgt cgcaattgct cgggcattat caatgaatcc agatgtattg ctattcgacg
    13321 aacctacttc ggcgttagac cctgaaatgg ttggcgaagt gcttaatacg atcaaagact
    13381 tagcacatac tggcttgaca atgcttatcg tgacgcatga gatggaattt gcaaaagatg
    13441 tatctgaccg tgtcattttt atggataaag gtgtgattgc agaagaaggt acaccagaag
    13501 atatctttgt ccatccgaaa gaagaacgta caaaagaatt cctttcacgt attttaaatg
    13561 cttaggatca atagctgatt gggacaaaga gctgcggtgt ttaccgcagt tcttttttat
    13621 gaattactca taaaaggtaa atttctgaaa attttggaat cttagttgtg tttttcagaa
    13681 aactctctta atatggaagt aattaaactt ttttagttag gatgatttaa aaatgaatga
    13741 agagcaagaa ctgcagcgtg gactgaaaaa tagacatgtc caactgattt ctattggcgg
    13801 agcgattgga acggggttgt ttttaggttc cggaaagtct atccagctag ctggcccttc
    13861 gatattgctc gcctatctta ttactggatg catctgtttt ttcattatgc gtgcgttagg
    13921 cgaacttctg ttatcaaaca ccaataacca ttcttttctg gattttgttg cagaatatct
    13981 tggcaaaaaa gcggctttca tcactggctg gacgtattgg ttctgctggg tatcgattgc
    14041 aatggccgat ttaacagcca tcggaatgta tgtacgctac tgggcgcctg gtgttcctca
    14101 gtggcttcct gaactgattg cattaggtct tcttctttgc ttgaatatgg tggctgtctc
    14161 attgtttggt gagttagagt tttggtttgc attgatcaaa gttgtagcga tcattgcctt
    14221 tatcctcgta ggagcttata tgatcctcac ccactatacg acagatattg gcacagccag
    14281 tatcacgaat ctatggtctc atggcggatt ctttccaact ggtgcaaaag gatttatctt
    14341 agctttccaa atggtaacct ttgcttttgc tgggatagaa ttagttggat tagtcgctgg
    14401 agaaacagaa aatcctgaaa aagtgttgcc ggaagctatc aataatattc ctatcaggat
    14461 catcttattt tacttaggat ctctttttgt cattatggca atctatccat ggaacagctt
    14521 gaatccagat aacagtccat ttgtagaagt attttcggaa attgggatca cgattgctgc
    14581 ttccttgatc aatttagtcg tattaagtgc agcagcttct gcctgcaaca gtgcaatata
    14641 tagtacagga cgtatgcttc gttctttagc gcaagaaggc agtgccccta aaaaattcaa
    14701 aaagttaaca acacatcatg tgccagggaa tgctttgaca ttttctacta tcgtcatttt
    14761 catttctgtt atcttgaatt acgtgatgcc tagtgaagta ttcacactag taagcagtat
    14821 tgccactact tgtttcttgt ttatctggag tatgcttgtc tacacgcaca tgaaatatcg
    14881 taaaagtatc ctcggcaaaa aagctcattc atttaaaatg ccgttgtacc catttagtaa
    14941 ttatctggta tttctttaca tggcctttgt gtgtgtcgtc ttgttcctag gaaaagatac
    15001 gagaatcgct ttattactaa cacctgtgtg gttcttgctt ctattactaa tctatcatat
    15061 gaaatatgaa cgtaagaagt aagaaagtag ttgtgacaga agtggtcagc ttcgagaaat
    15121 aagaaggaat ttacgaaaat tgcttcttaa atttttgtga aatttcggct tatttcttgg
    15181 agataaaagc ttctgtccca gcctcttttc tatttccccg gaaacaaccg ctgataatag
    15241 gcatctgctt ttttatagga aaaaatccaa ataccagata caaaaaaacg tccgaataac
    15301 ccgatcaacg gtacaaaaaa gacaccggca atcaagcata agttaatcat catggagata
    15361 agacttcgac ggtcctttga caaaactctc acgacatggg aatctggttt atttgctttc
    15421 atgatttgcc tcatcaagat accaaaagaa aaactccaca tcgtgtatac taagacataa
    15481 gccatctcag gccaaaaagc ttcagggtta cgcccgaccc aactagtaac agaaggacat
    15541 aaagtcagcc aaaagagcaa aaagatattc gaccagacca ctcggtaatt aattcgttct
    15601 gccatctgaa atatacgatg atggttcacc cagatcaccg caacaaatat aaagctgatg
    15661 gtataagcta ataatgtatt tcggatgacc cataaagaat gaaagctaga tgtattaggg
    15721 atcttgatct ctaatacaat aactctcaaa acaatggcta ccactccatc agtaaatgct
    15781 tctaatctcg actttgtcac gatgattcct cctcagatga ttcagcgctt ttattttatc
    15841 acttacgtta ttaaataacc atcgttttat atagggaatt ttctgaaaat tgttgcatat
    15901 ttttcgaaat tttgttactt ttaaaaaaac cgtaaaggag ttatgtatga caaaaaaatt
    15961 atcatttaaa gactatcttt ttataggctc catgcttttc ggtctatttt ttggtgctgg
    16021 aaatcttatc tttcccgttc atttgggtca agaagcaggc gctgctacct tttgggcgaa
    16081 tctaggtttc ttggttaccg gtatcggtct tcccttctta ggggtgattg ccattggtgt
    16141 atcgaaaagc tcaggtgtat atgaattagc aaaacggata aatcaaacat atgcgatggt
    16201 ttttaccatc ttgctttact tagttatcgg accgtttttt gctttacctc gccttgcaac
    16261 cacatctttc gagattggtt tagcaccatt tatcgatcct agcagacaga cgctatatct
    16321 agcaattttc agtattgtat tttttgtgct ggcttggtgg ttttcaagaa aaccgacaaa
    16381 gatattagat tatgttggaa agttcctgaa tcctgcattt ttggttttat taggtgcttt
    16441 gcttctcctt gcttttttga atccactagg ttctgtaaat caagcgccta ttcagccaaa
    16501 ttatcaagag catgcttttt tcacagggtt tactcaagga tataacacat tagatgcgct
    16561 tgctgcttta gcatttggga tcatcattgt cacaacaatc caaaacatgg gtgtaacaaa
    16621 acctgctgaa atcgctaaag acacgatcaa atctggtgcg atcagcatta tattgatggg
    16681 aatcatttat actttgctcg cttatttagg tgctatgagc ttaggtagct ttgctctaag
    16741 tgaaaatggc gggatcacgc tggctcagat tgctgatcat tatttaggta cttatggcag
    16801 tatcttatta gcatttatcg ttatattagc ttgcttgaag accggtattg gtttgattac
    16861 agcttttgca gaaacattca cagatttgtt tccgcaaaga aattacgcat tctttgttgc
    16921 acttgctagt atccttcctt gtttagcggc aaacgtaggc ttgacgaata tcattcaatt
    16981 ttcgttgcct gttttgatgt tcatctatcc attagcaatg acactgattt tactagtgtt
    17041 agttggtcct ttgtttaagc agcgtacggc tgtttatcga atgactactt attttacatt
    17101 gattgcttcg atttttgatg ggttgaacgc ttgcccagaa actatcaaac aaacacctat
    17161 tgttcaaaat cttttatatg ttgcggaaag ctacttgccg tttttcaaat tggggatggg
    17221 gtggatcgta ccagcagtta tcggttttgt tatcggactg atttggagtt tcgctaagaa
    17281 agaagaagta gcagattgat aaaagaggtt gtgaaagaga cgttcagcct tgagcaataa
    17341 aaagtaattt tgaaaaatgg cttctcacat ttttgcataa atttgactta ataccgagaa
    17401 actgactttt gaacaccgtt tattgagagg tcgtgaaaaa gccgcttagt ttcaagtatt
    17461 aagaaatatt ttgtgaaaat ggcttctcac atttttgcat aaatttgact taataccgag
    17521 aaactggctt ttgaacaccg tttattgagc gtctataaac tgacctgagt attagagaaa
    17581 caaaacggca aagtagctcc atatactttg ccgttttgtt ttgaactaat accgaagaga
    17641 agctgatcaa acaacatttc ttttataata tagattttag acatatatat gatataaaaa
    17701 tagttttcgc aaaaaaactt gggagcgtca ataattttgt gtaaataaat tgtcctcctg
    17761 caaaataatt agttactcag taaacattga aactaat
//
LOCUS       DAIGTA010000058        17231 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.061, whole genome shotgun sequence.
ACCESSION   DAIGTA010000058 DAIGTA010000000
VERSION     DAIGTA010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.061"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            6..320
                     /locus_tag="NOB43_002137"
     CDS             6..320
                     /locus_tag="NOB43_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982981.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            875..948
                     /locus_tag="NOB43_002138"
     tRNA            875..948
                     /locus_tag="NOB43_002138"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:909..911,aa:Ile,seq:cat)
     gene            complement(1464..1766)
                     /locus_tag="NOB43_002139"
     CDS             complement(1464..1766)
                     /locus_tag="NOB43_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982982.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(1986..2352)
                     /gene="ssrA"
                     /locus_tag="NOB43_002140"
     tmRNA           complement(1986..2352)
                     /gene="ssrA"
                     /locus_tag="NOB43_002140"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(2523..3296)
                     /locus_tag="NOB43_002141"
     CDS             complement(2523..3296)
                     /locus_tag="NOB43_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0982983.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMSNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            3440..3790
                     /locus_tag="NOB43_002142"
     CDS             3440..3790
                     /locus_tag="NOB43_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI0982984.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            3771..4487
                     /locus_tag="NOB43_002143"
     CDS             3771..4487
                     /locus_tag="NOB43_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0982985.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            4487..5935
                     /locus_tag="NOB43_002144"
     CDS             4487..5935
                     /locus_tag="NOB43_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0982986.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(6005..6514)
                     /locus_tag="NOB43_002145"
     CDS             complement(6005..6514)
                     /locus_tag="NOB43_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982987.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(6504..7229)
                     /locus_tag="NOB43_002146"
     CDS             complement(6504..7229)
                     /locus_tag="NOB43_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0982988.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(7452..9572)
                     /locus_tag="NOB43_002147"
     CDS             complement(7452..9572)
                     /locus_tag="NOB43_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0982989.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            9802..10980
                     /locus_tag="NOB43_002148"
     CDS             9802..10980
                     /locus_tag="NOB43_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HCI0982990.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            10996..11754
                     /gene="aroD"
                     /locus_tag="NOB43_002149"
     CDS             10996..11754
                     /gene="aroD"
                     /locus_tag="NOB43_002149"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCI0982991.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            11777..12262
                     /gene="ybaK"
                     /locus_tag="NOB43_002150"
     CDS             11777..12262
                     /gene="ybaK"
                     /locus_tag="NOB43_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HCI0982992.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(12333..13586)
                     /locus_tag="NOB43_002151"
     CDS             complement(12333..13586)
                     /locus_tag="NOB43_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0982993.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            13703..15052
                     /gene="gdhA"
                     /locus_tag="NOB43_002152"
     CDS             13703..15052
                     /gene="gdhA"
                     /locus_tag="NOB43_002152"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCI0982994.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            15164..16510
                     /locus_tag="NOB43_002153"
     CDS             15164..16510
                     /locus_tag="NOB43_002153"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCI0982995.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(16818..17204)
                     /locus_tag="NOB43_002154"
     CDS             complement(16818..17204)
                     /locus_tag="NOB43_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0982996.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5637 a         3037 c         3394 g         5163 t
ORIGIN      
        1 agcttttgga tttttacagt aattttatct taataatagc aatattatta cttctaaata
       61 tttggttttt tgataagagt agaaatgcag ggataggttt tagaaccaaa cgaagtacgt
      121 cttctgaaaa aaagtgggta tattcacaga ctatttttta cggaggggtt atttcaatca
      181 gtttactttc ttcaacactt tattctttta atgttataga cgtttccatg tcaaatttta
      241 tatctattat tggaatcctt atttctgcaa ttattacaca actacttctt gtgtttgaag
      301 agaagtcaaa aaataattaa agcaattatg ccttttagta caggaattat tacttcttac
      361 aaatgtatag cgaatgtgaa gcctgctgtt ttaattgttc tagaaaaact tttgagtgaa
      421 caattatttt atgttaggat gaattaattt ctctagagtt tataattaaa aaacttattt
      481 gaaggaacat gcttaaacca taattgtgtt tttccttcca tcagcataaa agttcacctc
      541 aaaaagagtg tacgaacaaa agttcttttt gtaaacctta aaatagattt tcctgaatac
      601 gtattgggga tttctaaatg tttgaatgtt tttttgaatg caaaatcaat gcaaaaaatt
      661 ttgtatttct ctacttttct ctccttgacc aaaataaaaa aacgttgatt taacaacgtt
      721 tttcatacat gtttatctgt ctcaaccata catatatgga gacgcatatc ttcactatca
      781 ctcataaata gtcacactcc aagatatgcg ataacaggtt tgttgccacg cattctactg
      841 gttgattgtt tatggcttta tgtggcaaca accactaccc ttagctcagt tggtcagagc
      901 agacggctca taaccgtccg gtcgtaggtt cgagtcctac agggtacatt aatgtagcca
      961 attgaatcgt tctgtgttag aattttttga agagtattat acaagctaaa gcttttcttc
     1021 attgccactc aaatgagtgg cttttttatg tatcctttta tggattaatg aaaggatgtt
     1081 tcacatagtt atacttctgt atatttgaaa agttttactt tgatttttaa atggaaagac
     1141 atttgggtta tattgtgaga taataataaa gaagagttta aagcgttccc caaaaaccac
     1201 ttccccataa gtgtgttacg ctttaaactc ttttatattt gaagccatta aaaagcatac
     1261 catataactg taaaaaataa tgggaaaaag acttataatt ggagtggtag ttaattagtg
     1321 acttattttt gattttatag cactgatact ataaaatata gatatcatca tattacacaa
     1381 tcttaatact aacttaaaaa atatcccttt tataagtatg gtgataaaat ccgttccggg
     1441 ctaccttttt taggtagcct actttaatct ttataccttt ctggatcaac gaaagtatac
     1501 ttcaaatagt cataacgccg atgatcgctc cgtgcgtctg gcacatcagt cacgatatca
     1561 aacaaaaaat acacatcttt cttcattctg gtttttgttg ccggaatttt aaagtagttc
     1621 ttattagagt aatagagatt gattaataag ctatcttcga ttgctaaaaa gaaaacttct
     1681 gaatcccaca ccttataaaa atctttgaca aatctattcg aaggatcaaa tttaaaccat
     1741 aattgtgttt ttccttccat caacataatg ttcacctcaa aaagagtata cgaactaatg
     1801 ttctttttgt aaagtaggaa tatcattgat aatatggatg gaacatatat attaaaaagt
     1861 gttctttttg aatgctattt tgaatgccat tttcattcat ttaacgaaaa tctgcgaaaa
     1921 taaaaaatgc tcaaaccctt ataaaataag gatttaagca tctagcgaaa tctgctgaaa
     1981 tctcacaatg gagacggcgg gagtcgaacc cgcgtccaaa cacatcgcca cttaaaaatc
     2041 tacgttcata gtcaactcat ttaaggattc actttacagc ttgccgagtg acaggcattc
     2101 tgtatcgcta gtctgatgtt ctctttttca acttacagac ggaaagttga aacgtatccc
     2161 actaaagtta ggacccttac tcgagcacat gggcgatgcc gagaggatct acgctaactg
     2221 tttttaggca gctaaagcgt aagagttgtt ttcgttttta gcagttatat ttaactgtaa
     2281 cgtttttacg tagacgtaac ctacgaaacg caattcaagc tcgactgtgc ctgtcgaatc
     2341 cgtaacgtcc ccgttagcta acaagggtta cgtgtatttt tcatacaaaa ttagtatagc
     2401 atatattggg ataaattcaa taaaaaagcg aatcatatcc cattatttat ataataactg
     2461 cccctttctt aagaaaaaat aagcgatttt cttaagaaaa gaggtagctt caaaaaaaga
     2521 tcttaaatca gatcaaaata cttcaatgcg tggacaattc cgccttctgt atttttcttt
     2581 gtgataaagg tagaaagttc ttttaatccg tcataggcgt tgctcatagc gattttgttg
     2641 tcgcaagctt ccaacaaggc aaaatcattc ggaccatcgc caaatccaaa agtaggaact
     2701 ttttccagct gaagttcttt ttgcagacgt ttgacacctg ccccttttga gattcctttc
     2761 ttcactgtat cgatcgagta aggaccattc cgataaaaag ttagctcagg aaaatgttcg
     2821 tgatagtatt cgtcacctga ttgagataag atcagcaaca tatttactgt gttttcttta
     2881 aagcctaaag gatcaatttc cggaacatct gaatgaatga agtcgtaagc attgatcatt
     2941 gtttggctat gaccggtaca ccagattttc tgatcgttat agtaagaaag ttcatgaccg
     3001 ttcaactgta catgatcata cattttttga cattcttctg aagaaaatgt ttgagaatag
     3061 atttcttcgc cgtctactcg aatgaaagaa ccattcatgg tgaccgcaga agtaatgccc
     3121 gcatcttcca tgatagagtg gatttctgct tctgtacgtc ctgtagcgat gacggggaga
     3181 acattgtttt cttttaatgc gttcatagct tttgccactt cgggtgtgat ttttgatttc
     3241 gcatctagta atgttccatc aagatcaaag aaagtgattg cacgataatt tgacacaaat
     3301 aaaactcctt ttttattgga ataagtttat cttaacaaag aatgaacaaa agacaaacct
     3361 ttcgtgaaga attcctgaac atattggttc agtcaacaat ttagagtata ctataagaag
     3421 agaatttagg agggaaagaa tgattttttt cagtattggt atcttattct taataattgg
     3481 cagtcttttt cggattctgc cctcaaaagg aaatctgcct ttttatgggt atcattcgcc
     3541 tcttgccgca aaaacagacg ctcattggcg gctggctcaa aagacaagcg gaaactggtt
     3601 ttttcttatg ggcttactga tggcattgat cggctattat ttaaagacat ctgggcatac
     3661 gaattatttt ctgattgaaa tgcttctgct agtatttcca attatgccta tttttattat
     3721 gacagaaaag aaattacaga aatatgacct ggaaactgga gggaacgata atgaatattt
     3781 taatgattga agataatcaa tctgtttctg aaatgatgca gatgtttttc ttaaatgaag
     3841 gttgggaagc aactttcaag tatgatggaa aagaagggct cgatgccttt ttagaaaacc
     3901 cacaacattg ggatatgatt acactagacc tgaatttgcc cacactggac ggtatgctag
     3961 taggaagaga gatccgcaaa gtttcaagta ctgtgccgat tatcatgctg acagctagag
     4021 attctgaaag cgatcaggtg atcggcttag agatgggggc agatgattat gtcacaaaac
     4081 ctttcagtcc tctgacgctt attgctcgaa tgaaagcttt gcatcgccgt agtgagttgg
     4141 cagaagcaag agaagaagca gtagtttcag atgatcattt tgatatcgag actagtcatt
     4201 tcaagatgaa tacgaaaaca cgagaagcgt atctggacaa ccggccaatt gaaggactga
     4261 cgcctaaaga gttcgatcta ttgtttactt tagcaaaaaa accacgtcaa gtattctctc
     4321 gggagcagtt gcttgaatta gtctgggatt atcagtactt tggtgatgaa cggacagtgg
     4381 acgcccatat caagaaatta cgacaaaaaa tcgaaaaggt cggaccacaa gtcatccaaa
     4441 ctgtttgggg agtcggctac aaattcgatg attctggtgt tgcctaatgc gttatttgta
     4501 tcagcaactc ttagctttct gcggaatggt cgcgttgatc ttattgatcg ttggagtttc
     4561 ttttacacaa ctgacaaaac aaacgattga agaaaacaat taccagcaac tgtttggata
     4621 tgctgaatca gttgaaaaga caacgcaaac ctatgccgat acgctcccgc agtttagtca
     4681 agatcaggcg tttcaaaatg cattgctgct gacagagcaa gtactgacag aacaaaatgt
     4741 gaactttata tttatcgata aaaacgaacg tgtcatttat ccgactaata cagctttact
     4801 gaattttacc ttaacagctg atcaatggaa aaatctgagg aatggacgtc aagaaaaatt
     4861 cacatcgaat aaaaatattt taggacaagc acaggcgacc tcttacgcac ttgtgccatt
     4921 taatttgaat catgaattct atggagcact tgtagttagt caacctgcgc gaaatatcga
     4981 taacagcgtt cgtccaatta cactgaacct gttcaaagga tttatttttt ccagtatcgt
     5041 tgcagttatt gccagctatg cttttgcagc attccaagtt aagcgtatca atcggttaag
     5101 gaatgcgacg aaagaagtga cgaatggtaa ttttgatgta cagctccccg tacatgacaa
     5161 agatgaattt gatgagttag cagatgattt caataaaatg acgaattcat tgaaagaatc
     5221 tcaagcagaa attgaagaac aagaaaatcg tcgaagacaa tttatggcag atgcttctca
     5281 cgagatgaga acacctctta cgacaatcaa cggacttctg gaagggttag aatacaatgc
     5341 aatccctgaa aatcagcgag aaaacgcgat taaattgatg aaaaatgaaa cagagcgtct
     5401 gatccgtttg gtgaatgaaa acttggatta tgaaaaaatc cgtacgaatc aaatcagtat
     5461 ggtcattaaa aaattcaatg gaacagaaac attgaaaaat attgttgcac agttagaagc
     5521 taaagcagaa gcagcaggag atacattgac attgaaagcc gttgatgata ttgatgttta
     5581 cgctgattat gaccgatttg tccaaatcat ggtcaatatt attcaaaacg cgatacagtt
     5641 tactgaaaac ggccaaatca cgattacttt agaaaaaggc tatcttgaaa cgatcatcac
     5701 gattgaagat acgggaattg gaatgtctga acaacaaatg aaaagtatct gggatcgtta
     5761 ttataaagta gatccttcaa gaaaaaatac aaaatatggt gaatcaggat taggtttacc
     5821 aatcgtgcag caacttgtac gcttgcataa aggaaaatta gaagtagaaa gcgaactagg
     5881 aaaaggaaca aaattcgctg ttcgtttgcc tgacgtagaa atcaaaaaag agtaaaaaac
     5941 aagcggtata aaagatcatg aatcgatctt ctataccgct tgtttttact ataaaatgat
     6001 tgatttagcc cgcgggctct aaacgatcaa tataaggact ttgagcaata gtagcatcat
     6061 gagtaaagag taagatacct tgattttctt catgagctaa ataagaaagc aagtggagta
     6121 gctcttggat ctccaataca ctaagttcat caaatgtatc ttcaataaca atattgtttc
     6181 gcttggaaag caaggcatga agtaattgca gctttacttt ttcaaaagac gtcaactcag
     6241 ctgccgcaca attaagcaag gaaggagaga tatcaagttt ttcttgatag gccaaacgat
     6301 cttgtttgat ttctttttcc ggtacatcca acaggacatg gtctttaaga ttcagataag
     6361 gaaacatcgg ccaatttttt tggatgatcg caaaattatc cagttttgca acaagaacct
     6421 cttttttcaa gtgctccaat attttatgct gtttttcgag aggacacaaa ataacggtca
     6481 agtgttcagc atgaatcaaa tattcaggtt tcattacgtc caggcctcct actttgcaaa
     6541 tgatggataa aaaaagtgaa agggaataga ctaagaatga gacagcatcc actgagccca
     6601 ataagagttt gggcaaatcc cttaagtata tctgtgaaaa aaagatcatt ttggaaatcg
     6661 atggtaaaaa aagtctgttg atccatcgga attgtaagtc cgcttaccga agtcaagata
     6721 tcacggatat ctggcagttc agtagtcttt aagacaagaa aattgatcct ttgaagaagc
     6781 gcttcataaa ctgactggaa gcttacgatc cacaataaaa ccaagataca acaaagaaag
     6841 agaggaaaga acagctgcca gaaaataaaa aggaataatt tggttttaga aagaccagtc
     6901 aggtgccaat tgatcaattc ctgcttgttt tgcctgactg aatagtaaaa gaaaaagata
     6961 aaaaggaagg caaatagaaa aaataaactg aatatgcctt ttatataaaa tcggctagct
     7021 aattctaaag ccggaagaag ctctgtagat gcagaagcgc caataaatga aagccgatct
     7081 tggacttgat tggctaaagc cgattgcaaa tggtaaagag tcaggcatgc tatcaataaa
     7141 aaagcagaaa agcttgaaaa taaacaatag agtattgtct gctttttgta ataaattaat
     7201 cgagcagtag catagcggat tattttcata cttttcacct ctataaaaag tatagaaaat
     7261 gaatatgaat aaagtatgaa attcctttag tgaaatcacg aattaaaacc agaaaatatt
     7321 ttgtaaaaag caagaggttg tgaagaagct gccctattct attaccgtag atgcaagctt
     7381 ttgaacactg tttattcgaa aagaggagca gcgacaataa ttttgtcgct gctcctttta
     7441 aatttatttt atcattcgga agaacttgtg gtcgttccgt gaagttcttg gtacgtttgc
     7501 gttttataaa gatcaacagt tgattgtccg ttgtgttcac taaagacact agttgacttg
     7561 tcaccaagag atttttcagc ttcttttaat ttctctaagc cattcttgta gtcataatca
     7621 ctggtatcaa ttgggtctaa tccactattc gtatagaacc gaagaagatc accattattg
     7681 atttggtcag aaacagctaa ctgtttatca actttttctt tcagtgaatc aatttcattc
     7741 tgtacttcct cagtaggttc agtaatagct tcaccagttt cgttactata gatcgtacca
     7801 ccgtagtaag tatattttgg tgtaacaaaa tcaccatcac ggaaagaaac aagctgttca
     7861 tgatctttcg agaatagatc ttgtcctaac tgaatataat tttttgtatc tacacctagt
     7921 aagtgaagta atgtaggcaa ggcatcaact tgtccgccgt aagtgtgatt gattccgccc
     7981 tgtgtttgtc cagggatatg gatcatataa gggacacgct gcatttgtgc attgtcgtag
     8041 tttgtccaag tagaacttgt ttttccaact aattcagcta gatttttatt tcttgaattc
     8101 gagacaccgt aatggtcacc gtaaaggacg atgactgaat tatcatacaa gccgctttct
     8161 ttcaaataat tgaagaattc ttgtacggcg gtatctaaat aattggctgt cgcaaagtaa
     8221 ccgttgatcg tttcatcatt tgtattggct aacgggaatc ctgcttcgtc attggtgaat
     8281 tttgaataag gataatggtt agatacagca atgaattttg aataaaatgg ttgttgcaga
     8341 cgttccaagt attgtacgga ttgttggaaa aatggtttat catgcaaccc gtattggaac
     8401 gaattgtcat cattaacatc ataataagaa gaatcaaaga aataatcata tcctaaattc
     8461 ttgtatgtct cgtttcgatt ccagaatgta ccagcgttcc catggaatac cgcactaatg
     8521 taaccttgtg tttgacttaa aatatcaggt gcagcttgga aagtattttt tccgcctaat
     8581 tgtgtgaaca aggagccttg attcaagcca aacaatgaat tttccatcag cgtttccgca
     8641 tcgcttgttt ttcctgcttt tacttgatgg aaaaagttgt caaaactgaa cgtgctgttg
     8701 ctgtggtaaa gactattgat gaaaggtgta acttcatgct ggagaccatt ctcatctgtc
     8761 aatttataat cgatcaggaa ttgctggaag ctttctaaat ggatataaat cacatttttt
     8821 cctctagcga gcccgaacaa atcgtcattt ggtgctgcat aatgttcttt tacataattt
     8881 tctacttctt tcatatcatt gggacttgct tctgcccgca cttggtttgt ctggtaagtt
     8941 tgaacaccgt cataaaccat gaaagcattc aagccaagat atttgaccaa ataatcacga
     9001 gagaatgttc gagtcagcaa ttctggacga tcagcttccg ccataaaaag atttcctgag
     9061 aaaatcataa ctgctaatgt agagatcgca aaagccattc ttgctcggat cgggcgaggg
     9121 tccaacttga ttttttttgc aatcagcaga acagtcaaga taataaaatc gatccaatag
     9181 atcacatcat atgggcgaaa cagtcgaatg gcactttctc ccagaccact cgctactttc
     9241 ccagcaccta aaatcgtgtt gatcgtaatg aagtccgtga attctcgata ataagtgaca
     9301 ttcgaaaaaa caagcaatgt caaaagaaaa taaatgacca tcatcgtgat ataagcaact
     9361 ctagggcgtc tgatataaag agcaattcca agtaataaca atgtagttgc aatagggttg
     9421 ataaacaaga taaagtattg aatgccactt tcgattccga gatggaaatc aactaaatag
     9481 gcaaaaatcg ttttcaacca aagtaaaacg actagtaaag aaaaaaatcc gagcctctta
     9541 ttcaaaaagg caggtgtttt tatacatttc aagataatct tcctttctgc acttcttaat
     9601 cacagaagtg tcctgaaacc atgttacaca gctcacttat tctcatttat tttactagta
     9661 tgacaatata gtgtcaattg aaaccagaag tttatgctgt ttcattaagg ttttctttaa
     9721 gcttcatgaa aaaatgagca gtaagacaag tcctatgttt tttgttatac ttgggaagag
     9781 aaagctaaag caggtgaagg aatgaaagta aaagtaaaaa aaagagcaag caatcgattg
     9841 aaaaaaggat atccactgat ccaaaaagaa gaccttgctc atccccaaaa agaaaccacg
     9901 caatgggtgg aattagttga ttcgcaaaac caatttatcg caaaaggata tctaggaaag
     9961 cagaataagg gaatcggttg ggtattgagc cagcagaaca tcccatttga tcaatctttt
    10021 tttgaagaat tttttgtgaa gtcaaaagaa aaaagaactt tctttttttc agatgattct
    10081 actaccgctt ttcgtatatt caatggagaa ggagacggga tcggcggtct gattgttgat
    10141 tattatgcag gttatgctgt tttttcttgg tataacgaaa cgttatatgc acatcgtgaa
    10201 ttattgattc aagcttttcg tgaaatctac ccggaaatca taggaggcta tgagaaaatt
    10261 cgatttgaat cagtaaatct gcctgagagc cagttcattt acggaaaaga ggcaccggaa
    10321 cccttgatcg taaaagaaaa cggagtaaaa tttgccgttt atttaaatga aggattaatg
    10381 actgggatct ttttagacca aaaagaagta cggggatcat tagcagaagg tttcgcttct
    10441 gggaaaacag ttttgaacat gtttagttat accggcgcct tttctgttgc tgccgcaatg
    10501 ggaggggcaa tcgaaacaac aagtgtcgat ctagcaaaac gcagtttaaa aaaaacacag
    10561 gaacagtttg aagtgaatgg tttggatgtc gatcagcaaa aaatcattgt tatggacgta
    10621 ttcgagtatt tcaaatacgc caaaagaaaa caatttttat atgacatgat tgtattggat
    10681 ccaccaagtt ttgccagaaa taagaaaaaa gtctttcgcg tagcaaaaga ttatggggaa
    10741 ctggtcaagg atagtctgga tattttagca gaagacggga tacttattgc gtctacaaat
    10801 gctgcgaatg tctcgataga acaattccaa acaatgattg aagaggaatt ccatgccaaa
    10861 aatgtttctt ttgaacaact tgctttatat cgtctgccaa aagatttcca gacgacggat
    10921 acctttttag aaggcaatta tctgaaagtg tttgtttatc aaattaaaaa taaccattag
    10981 aaggagcgat gcagaatggt tcgggtaaag ggattgaata taggaagcgg tagaccaaag
    11041 atttgtgcgc ctcttatcgg ggccgtccga gaggaagtat tacgtgaagc agttcttgca
    11101 cgtgaagcag gggccgattt agtcgaatgg cgagtcgatc attatcgtga agttttttct
    11161 tttgatgaag tagcagaaac attggttctt atccatgaga tgcttgatgg actgccgtta
    11221 ttatttacgt ttcgtacctt agctgaaggc ggagaacaag acatatcgat ccgtcagtat
    11281 cgcgaccttt atgaacatgt gatacacaca ggattagtag atatggtcga tatcgagttg
    11341 ttcaaagtag aaagtctagg aaaaagactg atagaggaaa tcaagtcttt aaacattcct
    11401 ttaattatca gtagtcatga ttttaaagaa acaccagcag accctgtctt gctttaccga
    11461 ttgaatgtta tggaacattt tggagccgat atcggaaaac tggcagtaac tcccaataat
    11521 gaacgagatg ttttgcggtt gatggagttg actagacggg caaatgcttt tgtctccatg
    11581 cctattatta cgatgtccat gggaaatctt ggtaaaattt ctcgtctggt tggcggaacg
    11641 acgggttccg ttatgacatt tggttcctta agcagcgatt ctacttctgc tccaggacaa
    11701 ttaccggtca aagcattgaa gcaaattatt caattattaa atgaaccgtt gtagaacaag
    11761 tttgaggtga tattttttgg caaagaaaaa aatagtaaaa acgaatgcaa tccgtatggt
    11821 cgaacaaaaa aagattccct atacagagca cgaatatgag tgggacgaaa gccacctaag
    11881 tgcgtcatcg gtcgctgaac agcttccaga aagccaatct cgtatattta aaacactggt
    11941 tgctgtgggc aatgtgacgg ggcctcttgt tgctgtgata ccgggagaag ccgaattgaa
    12001 tctaaaaaaa ttagcaaaag tttcagggaa taaaaaagta gaaatgctcc atttaaaaga
    12061 tttggaagca acgaccggat acatacgtgg tggctgctcg cctataggta tgaaaaaact
    12121 atttcctact tatttagatc aaattgcaga aagctatgaa caaatcattg tctcggctgg
    12181 cagaagaggg ctacagatgg agttagcacc tcaagatatc tgtgcattaa cgagcggaca
    12241 atttgcagat ataaaacaat aaatcatacg tataaaagaa agaaggaggc cgggatgttg
    12301 tttgtccagt ctccttcttt cttttttata cattatgctc tttgcccggc attcattcct
    12361 gctacatgcc ctgtagcgaa agccgctgtg atattaaagc cgccagtata accattgaca
    12421 tccagtaatt ctcccgcaaa atacagacca tcaatgattt tactctccaa tgttttagga
    12481 taaatttcct ttagagaaac ccctccgcca gttacaaatg atttctcaat aggaaaagtt
    12541 ttgttgattg atagcttaaa ctctttgcat agttgaacaa aatcttgaat ttgtttttga
    12601 gaggcttgtt gtcctgtcag atgatccatt tcaagccgct caagaaagaa aactaacaat
    12661 cgctcaggca atataccatg ccaagcattg accaagttct ttttggttgc tttacttttt
    12721 tctgtcaata tatgaataag ctcttgtttg gtttgtgtag ggaaacaatc cagagaaagt
    12781 gtcactggtt ctcccgtttt ctctaattct ttattgacaa aacttgaaca acgcagtgca
    12841 gccggaccag aaataccgaa atgggtgaaa agtaaatcca tcgtatgttc agtcaataca
    12901 cgaccttttt tatttaaaac gcgtaaagtg atgtcttgta aagaaagccc ttgaagtgtt
    12961 ttctcctgaa tatacggttc atccgatatc aagggggact ctgtcgcata aagaggcgtc
    13021 accgtgtgac ccactcgctt cacgatcttg tacccatctc cagtagaacc agtagatgga
    13081 taagtccgtc caccagttgt taagataatg gcaggagcat ggaactcttc gaattccgtg
    13141 cgtataccgt aaattttatg ttctttgtgg atcaatttct ctactcgagt agagaataga
    13201 agcgtcacat ctagttcttt cagacgattg agcaatgctt cgataatcgt ttttgattta
    13261 tttgttacag gaaacatccg tccatgatcc tcttctttta aatgtacgcc ttgtgattca
    13321 aagaagttca tgatatcgaa attattccat tgcgcaaacg tactatataa aaactttcca
    13381 tttccaggaa tatgtgcaat caaatcatca acaggacgat tgttcgtaac attgcaccga
    13441 ccaccacctg tcatcagtag tttttttcct gcttttttgt ttttttcgat caagagtacg
    13501 cgtgcgcctt gttcagctgc actgatcgct gccatcatcc cgcttgttcc agcgccgact
    13561 acgatcacat catacagttt ttccattccc tcacctcaag gaaagtgtag catatctgaa
    13621 gaaagaaaac agaaaaaaat gttttgagcc aaaagagaaa atgagctaaa atgagggaag
    13681 ataagcaaag gagcgtggaa cgatgacaaa cgcaacagaa tatgttcaag caattcaaga
    13741 aaagctacat caaaaggatc aagggcaaga agaattttta caagcaatcg atgaattcat
    13801 gcccacggtt atgtcttttt tggacactca tcccgaatat atcgaaaaga atatcttaga
    13861 acttttaacg gaaccagaaa gagttattca atttcgagtg ccttggcaag atgatgaagg
    13921 aaactggcga gtaaatagag ggtaccgtat ccaatacaac tcagctatcg gcccttataa
    13981 aggtggattg cgcttccatc ctagtgtcaa tctaagtatc ttgaaatttt tggcttttga
    14041 acagattttc aagaatagtt taaccggtct gccaatcggt ggaggaaaag gcggaagtga
    14101 cttcgatcct aaaggaaaat ctgataatga gatcatgcgt ttttgtcaaa gtttcatgct
    14161 ggaattgtca aaacatatcg gcccatcgat tgatgttcct gcgggagata tcggtgtagg
    14221 agctagagaa atcggctatt tgttcggcga atataaacga ttgaaaaaat atgatactgg
    14281 tgtgttgaca ggtaaacctt tggatttttg gggaagtaag atacgtacgg aagctactgg
    14341 ttatggatta gtgtattatg tcaaacatct attgaacgaa gaaaaagatt catttaatca
    14401 aaaaacagtt tttgtttccg gaagcgggaa tgtagccatt tatgcaatcg aaaaagtgca
    14461 agagctaggc gggaaagttg ttacatgttc agattctagc gggtacatct atgatccaga
    14521 aggaatagat gtgaaactat tgaaagaagt caaagaaatc aatagacaac gtttgacgga
    14581 atacgcaaac caacgtcctt ctgctattta tcatgctgga gaatctgttt ggacattgaa
    14641 agaaaaagcg gatatcgctt tgccatgtgc tactcaaaat gaaatagacg aaagcttggc
    14701 cgaaatctta gtagaaaatg ggatcaaaat cgtagcagaa ggcgctaata tgccatgtac
    14761 agtaaaagct gtttctgttc ttcatgaagc aggcgtgtgg tattgtccag gaaaagctgc
    14821 taatgctgga ggagtagcag tatctgcttt agaaatgagt cagaacgtcc agcgattgac
    14881 ttgggaaaga gagcaagtgg atgagcagct ggatcaaatc atggaaacga tttaccatac
    14941 gtgtcgccaa acagcagccg agtacggcga cgaaaaaaat ctgcttcttg gagcaaatgt
    15001 tgctggattt gaaaaagttg ccaaagcaat ggcagcagaa ggtttagttt gaaaaatgaa
    15061 actttcttgg aaatattgtc agcattttgt ttatttgctt gaaaaataat aaaaaaaaac
    15121 gtaaagtatt acctgtagag taaacctata aggaggagaa caaatggcac acattcattt
    15181 tgactattca aaagtagcac cgtttgtcaa cgaacaagag ttagggtaca tgcaaagcca
    15241 agtaacagca gcccacaacg aattacggga aggtactggc gcaggaagcg acttccgcgg
    15301 ctggatcgat ttaccaacga actatgacaa agaagaattt gcacgtatca aagaagcagc
    15361 taaaaaaatc caatctgatt ctgaagtatt agttgttatc ggtatcggtg gttcttattt
    15421 aggcgctcgt gcagcgatcg acttcttgaa tcacacattc ttcaatttat tagatagcaa
    15481 cacaagaaaa gcaccacaaa tcttctttgc cggaaattca atcagctcaa catatattgc
    15541 tgacttgatc gaagtaatcg gtgatcgcga cttttcagta aacgttattt caaaatctgg
    15601 aacaactact gaaccagcga ttgcgttccg tgtattcaaa gagcttcttg ttaagaaata
    15661 tggacaagaa gaagcaaaca aacgtatcta cgctacaaca gataaagcaa aaggtgcagt
    15721 taaagtagaa gcagatgcag aaggttggga aactttcgtg attcctgatg acatcggcgg
    15781 acgtttctct gtattaactg ctgttggttt gttaccaatc gctgttagtg gtgcagatat
    15841 cgatgcattg atgcaaggtg ccgctgatgc aagcaaagca tactcaagcg acaaactaga
    15901 agaaaacgaa gcttaccaat acgcagcaat gcgcaacatt ctttaccgta aaggcaaagt
    15961 aactgagttg ttgatcaact atgaaccagg aatgcaatac ttctcagaat ggtggaaaca
    16021 attgtatggt gaatctgaag gaaaagacca aaaaggcatc tatccttcaa gcgcaaactt
    16081 ctcaactgat ttgcactctt taggacaatt catccaagaa ggacgtcgca atatttttga
    16141 aacagttgtg aaggttgaaa aacctcgtaa atcaatcaca attcctgaac aagcagaaga
    16201 tttagacggt ctaggctact tgcaaggaaa agaagtggac ttcgtaaata caaaagcatt
    16261 tgaaggaaca ttgcttgctc atacagacgg tgacgtgcct aacttgctag tcaaaattcc
    16321 agaaatggat gcttatacat tgggttatac aatgtacttc tttgaaattg ctgtaggtat
    16381 ttcaggttac ttgaatggaa tcaacccatt cgaccaacca ggtgtagaag cttacaagaa
    16441 aaacatgttc gcacttctag gcaaaccagg ctttgaagat cttgctaaag aattgaacga
    16501 acgcctgtaa gataagggtt tttcgctaga tttaaataat cagtgataga aacatgttcg
    16561 ctttaaaatg aaaactggta cccatttagg tactcaaaca tactgcatcg tttattcaga
    16621 ataaggggct gtgacaagac gtttgtcaca gtcccttgtt tgtatagaaa tcgattgatt
    16681 gccttgctct ttagtttgtt ttaggacttt aagaacagtg aggctgactt cgaaggttaa
    16741 ttctgttttt ttgttttcta gaatcagtaa gcaaaaaagc actcacttcg agtgcttttt
    16801 tgcgatatat tcttagctta agataggcct aatttttctt ttacagatga gggtacctta
    16861 tcgctggtaa ttactttttt ctctatgatc cgcttttcgc ttgctttcaa ctgcaagatc
    16921 gttccttcgg ggtaagcaga accattggca gagtcaccag aagtaatgac atcgaaatct
    16981 aactgtcttt tttcaccgtt ttcagcataa gcatctacgt tgtatttaaa acctcttcca
    17041 attacttccc cattatctgc tttgatatca gtttctgcag gcattggagc tttgactacc
    17101 gcataataat ctttacctac ataagtagac tgatagtagt cccaaccttt ccatcctata
    17161 aaagcaatca atatgataac gatcaaccct aaaatttttt tcatgaaaga tctccttttt
    17221 tatttttatt a
//
LOCUS       DAIGTA010000059        17008 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.062, whole genome shotgun sequence.
ACCESSION   DAIGTA010000059 DAIGTA010000000
VERSION     DAIGTA010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.062"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..127)
                     /locus_tag="NOB43_002155"
     CDS             complement(<1..127)
                     /locus_tag="NOB43_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HCI0982997.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(231..542)
                     /locus_tag="NOB43_002156"
     CDS             complement(231..542)
                     /locus_tag="NOB43_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI0982998.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(544..741)
                     /locus_tag="NOB43_002157"
     CDS             complement(544..741)
                     /locus_tag="NOB43_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HCI0982999.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1135..2862)
                     /locus_tag="NOB43_002158"
     CDS             complement(1135..2862)
                     /locus_tag="NOB43_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HCI0983000.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2855..4048)
                     /locus_tag="NOB43_002159"
     CDS             complement(2855..4048)
                     /locus_tag="NOB43_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0983001.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4235..4879)
                     /locus_tag="NOB43_002160"
     CDS             complement(4235..4879)
                     /locus_tag="NOB43_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0983002.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4973..5107)
                     /locus_tag="NOB43_002161"
     CDS             complement(4973..5107)
                     /locus_tag="NOB43_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HCI0983003.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="NOB43_002162"
     CDS             complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="NOB43_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCI0983004.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7238..7711)
                     /locus_tag="NOB43_002163"
     CDS             complement(7238..7711)
                     /locus_tag="NOB43_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCI0983005.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8112..8336
                     /gene="nrdH"
                     /locus_tag="NOB43_002164"
     CDS             8112..8336
                     /gene="nrdH"
                     /locus_tag="NOB43_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCI0983006.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8495..10654
                     /gene="nrdE"
                     /locus_tag="NOB43_002165"
     CDS             8495..10654
                     /gene="nrdE"
                     /locus_tag="NOB43_002165"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCI0983007.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10704..11669
                     /gene="nrdF"
                     /locus_tag="NOB43_002166"
     CDS             10704..11669
                     /gene="nrdF"
                     /locus_tag="NOB43_002166"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCI0983008.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11758..12897)
                     /locus_tag="NOB43_002167"
     CDS             complement(11758..12897)
                     /locus_tag="NOB43_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0983009.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13206..13919)
                     /locus_tag="NOB43_002168"
     CDS             complement(13206..13919)
                     /locus_tag="NOB43_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCI0983010.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="NOB43_002169"
     CDS             complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="NOB43_002169"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCI0983011.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15108..16640
                     /locus_tag="NOB43_002170"
     CDS             15108..16640
                     /locus_tag="NOB43_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0983012.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16831..>17008)
                     /locus_tag="NOB43_002171"
     CDS             complement(16831..>17008)
                     /locus_tag="NOB43_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0983013.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3495 c         2910 g         5324 t
ORIGIN      
        1 atgaaaaaac acattccact aaatttgatg ccggttttcc ttgaggtttt gttccagcac
       61 ctcctttaat ttttttaagc tcttgatctg aacattgttt agcatttagt ctattttttt
      121 cttccattac gattccccct acaaactata aatactttta tgtcactgat tcaatatacc
      181 tatttttcta atcaaaaaat tttgagacat atttaatatt ataagtatca ttaaaattga
      241 gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct tccaatttca
      301 ctcaaatttc ttattaattc ctcttgatat tcagtgaatc ttattttatt agtataagca
      361 gtaaaatata gataattcac caatctattt attaaaggac tgggatctaa ttcatatttt
      421 tgtttttcta attttaaata taccttttgt aaaacctcaa gaatatcaga atatttagga
      481 tctttactta tagatatatc attatataat tcatgaacaa tttgcttagc attttttttc
      541 attttagcac ttccctggaa ttgctccacc taaaaaacca cctatagaca ttcctgcaat
      601 acaagtagtt gccttggccc aatcgaccgt acatttattt ttagtgcaat acactccatt
      661 tccataatat tttccactat gagtggtacc cccatagata agttgtgtct ctttaataga
      721 caaaattttt aaatgtttca taatctaatc acccctaaat taatgttttt agactattat
      781 tctaacattc attaaatttc aaaaaacaat tccttcttga aacgtagcaa aataattcct
      841 gaataagaat ttaatcactt ttaagtatat aaactatgta tattctttaa tattttttga
      901 gaatgcactt cgtacataat aaactttaat cacattagtc tttcatacct acgatcgatc
      961 tctttgactc gcacccataa attcataata gtttgtcggc gtctttgaac gtttcgaaga
     1021 tgagctacgc attctctttt tttatagaca aaaaagatag agacgaacat ggagcttcca
     1081 aatttggata tttgatccaa ttttggaagc tccatttatt tcgtgtctgt ctttttattt
     1141 tttccagctt tcgactaatt cttggttctc tttgatccag tcttttgctg cttgctgtgg
     1201 atcttttcca ttgttgattt ccaacataac tttttccata tctttttctg accaatggaa
     1261 attgtctaat actttgtaag cttctggctg gtcttctttc aatccttttc gaaccatcgt
     1321 atggatctgc tcttcgcttc ccattccgtt ttcaggatct tctaagtatt tcagatcata
     1381 tttggcaaac atccaatgag gtgtccatcc tgtaactaca attggttcgt gttttttgat
     1441 cgcttgacct agtgcaacgg tcattgctcc tgaagaagat gtctctactt tccagtcttt
     1501 caagttgtca tatttttgga tcgtgttttc agcagccgta actacaccag ctcctggctc
     1561 gattcctatg attttcttac ctgcctgatc ggttaactca tcgatcgaat ttacatccat
     1621 gtaggctggc actgctaaac caacttttgc tcctgtcaaa ttggcaccta ggtcttcgac
     1681 ttgatcttta tattgtgcat attgtgaacc atgagtttta ggtagccaag ctgaaaccat
     1741 ggcatctgac tcgccatttg aaacagattt ccacatgatt gaattatcta atggcgtcat
     1801 cgttacatca tagcccattt gtttcaatac ttcaccgact acatttgttg aagcaacttc
     1861 tgtatcccat tcaacataag ataagttgat acgttttgtt tctttggcag atgaaaaact
     1921 ccctatacca atcgcaccta agatcactac tactacagca ccaatgatca gtccttgacg
     1981 ttttttactt ttctgtgttg ttgctcctgc agctttttta ttgtttggct ggttcaaatg
     2041 ctgtgtaaaa cggtcaatga tgattgctaa gataactaat gcaaccccgt tgacaaatcc
     2101 attcccgact tgtgctcttt gcaatgctga taatacgccg cgtcctaagc cgggtgcacc
     2161 gatcatagag gcaataacga ccattgaaag tgacagcatt gttgtttgat tgatccctgc
     2221 catgatcgta cttttagcta aaggcaattc tagtttgaat agtttttgac gacttgtgct
     2281 cccgaatgaa tcagaagctt ctactaattc tttaggaact tgtcgaatcc ctaaattcgt
     2341 aaaacgaacg gttggtggca gagcaaagat gactgaggca aatacccctg gaaccatccc
     2401 gataccgaaa aatgcaactg ctggaatcaa ataaacgaat cctggcattg tctgcataaa
     2461 gtcaaggatc ggtttgataa tactttgggc tttactgctt tttgccatca agatccctaa
     2521 tggtacccca atgatgatcg agatcacact agataaaaga acaagtgtga cagtattcat
     2581 caaatcattc catagacctt ggttataaat aaaccataga ccgattaatg tgaacaacgt
     2641 aagtcctgga cgtttcttag aaataaagaa agctgctacc gtcaataaca agataaacaa
     2701 aggagctgga atcactaaca gtaaatttgt aatccccgac atcactgcct gtccaatcgt
     2761 ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga tattttctac
     2821 ccagtttgcc actggtaatt gatagttcaa tagattattc atgttcactc acctcgcttg
     2881 tttctgctaa tgcttcaatc acactacctc ggatgacgac accttttaat tttccatcct
     2941 ctacaactgc aagtggagtc ggtgagtcat aaataatatt gaaaatatca cttaccacca
     3001 tgtctttccc aatcaccgtc acattttcat ctaggaagtc gatcaatgga cgtttttgct
     3061 tcctagcttc taacgcttga tctgcagtga tgatcccttt caggtgtctc tttctgtcaa
     3121 cagccatcag catgctgact tcttcattac gcatccttgt caatgcaacg tttggtccat
     3181 cagattcgat attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta agcactttgg
     3241 aacgatcgac ttcttccaca aattcacgta cataatcatt tgctggattg gtcaatattt
     3301 cttcacctgt tccgatctgc atgatttcgc cgtctttcat caaggcgatt ctgtccccaa
     3361 tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat cgttttttga acattggctt
     3421 gcaggtccag taattcgtct tgcatttctc gccggatcag cggatcaaga gccgagaacg
     3481 cttcgtccat cagcaagatc tcaggatcat ttgctaaagc tctggctagg ccaacccgtt
     3541 gttgcatccc accagataac tgactaggat attggtcttt aaatgaaagc aaactagaat
     3601 tttctaatgc tttttctgct ttttcttgtc gttcttcttt aggtacacca cggacttcta
     3661 acccgtattc tgtattttcc aagatcgttc gatgtggaaa cagaccgaag ttttggaaaa
     3721 ccatattgat tttatgacga cggacttctc gcaattcttc tttgcttaac ttcgatacat
     3781 cttctccatc aatatagata ctgcccgaag ttggctcaat cagacgattc aatagacgga
     3841 tcaatgtgga tttcccactc ccggaaagcc ccatgatcac gaagatttct ccttctttta
     3901 cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt tttctttaaa atctccgttt
     3961 tcggctggtg atcattcatc atatctaaag cggcttgtgt ctttttacca aatatctttg
     4021 ttaaatgttt tacttctact tttaccaaac aaattctcct tttttatgta aattcatttt
     4081 tctttctgaa aaaagtgacc acactatgtt aacatcatgt agtcactttg tcaaaaatga
     4141 aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa taaaaggttt
     4201 agccaagtta atattttttt aatatttcac acaatcattc tgcaagctga tgctccgggt
     4261 aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc aataaaatga acgatgtccc
     4321 ctgccgtaaa tttagcatag gggccaggtg aaacaagcag ttcttcatta tgagaaattg
     4381 cgataactgt ggcgccagtc gcctgccaga tattcaactc gctaattgaa cggtccagat
     4441 gcattgcttt ttctgataaa gataattcaa acggaagtaa aggattcatc ttatgtattc
     4501 gcttcgtttg attgaccagc tgatccaata attgagaaaa atgattcagc tcatcttgtt
     4561 gcttctccac acttgccatg atttctgctt ttgtatcttg gatggattgt acatcttgat
     4621 attgcaatag gaaatctttt gctttttcct tcgaagcaac aaatgcccca cttccatgcc
     4681 gtacttccat gattccaaga tctaccagca cattgatagc cttgcgggta gtctcaggag
     4741 aagcattgta cgtactggca agtgttgagc gggcatggat cttctcaccc actttatatc
     4801 ggttttcaac gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc gggcggacga
     4861 tttttttctt tccagacatt ttctttcctc tttctttttt tactttccct catcttacta
     4921 tgctctagca aaataagcaa aaaaggggag aatagcctct tgcaacgact gatcatcgct
     4981 tgatctgttc cttttttact gggcaagctg tttgacagtc atcacaattc ttaccggatt
     5041 ttaaacgagt atagacaatt gcgcctgcac ttccaaagat taacacactt aataagaatg
     5101 tcgccatcct attcctctcc ttctaatgac aatatagtat aaaactggtt cttggatttt
     5161 ggctgacgga acaaaacata aacgagtcct atcatcagta aaatagcaag atacgtccct
     5221 aacgctacct gtccaccctc caataagtgt cccaactgat aaatcacaaa actaactaaa
     5281 taagctaaac cgcattgata gcctatggcg atccaagtcc atttcttggc attcatttcc
     5341 cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa ggctaacaat
     5401 gaataagctg ctgcgggagt atatgtgtgt tgtagcactt gccagatttc tctgccattt
     5461 tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc caataatatt ttctttagcg
     5521 accaatcctg taatcgctgc gactgttcct tgccagtttc cccaaccaag cggctgaaaa
     5581 acaactgcca ggattcgccc gaaaaaggct aagatacttt ggtcttcaga aacaggttga
     5641 gcataaaaat tataagaaga gctgaaccag atcacgatac tagaaacaaa gataatcgtt
     5701 cctgcttttt taacaaaaga cttgctgcgg tcataggttt gtcttaggac cgctgaccat
     5761 tgaggaaaat gatatgcggg caattccatg ataaaaggag ctgtatctcc agcaaacaaa
     5821 cgtgtttttt tcaagctgat tccagagaaa ataattgcag tcataccaag aaaataggca
     5881 gaaggagcta cccaagattg atgaggaaaa aaggcccctg ctactaaggc aataatcggc
     5941 aactttgcag aacaaggcat gaaggttgtg accatgatcg tcaaacgacg atcttgctcg
     6001 ttttcaatcg tgcgactggc catgacgcct ggcactccac atcctgtagc aatcagcata
     6061 ggaatgaagg attttcctga aagaccgaat ttcctgaaaa gtcgatccat gacaaaagcg
     6121 atcctcgcca tatatccgca gtcttccaga aagctcaagc ataaaaacaa tataatcaat
     6181 tgcggtagaa atcctaacac tgctcccacg cctgcgatga tgccgttcaa gatcagctcc
     6241 tgcatccatc ccgctacttg ccattcagct aacaatctgc caacatgttc tggtaaccat
     6301 gtaccaaaca atgtgtcatt gatccaatct gtccccattg ttcctactgt ttgaatagcc
     6361 agataataga tcagccacat cacaaatgcg aagatcggca aggctaacca acgattcgtt
     6421 gcaatctgat cgattttgtc actcatcgat aattggaaag aatcatttga cacaacacag
     6481 agtgtacata gttgggtaat aaattcataa cgttcattga ccagaatcgt ctcactatcg
     6541 tcgtccaata gtttctctgt taactggatc agttgctcga tctctttttg ctgagaaact
     6601 gctatctcgt aatcctctct taccttctga tctcgttcaa aatatttcat tgcataccag
     6661 cgtttcttgc cgctttgttc tcctagtaca tcttcaattt catgtaaagc tgcttctaaa
     6721 cgtggatcat atgtacaggg aacaggaata gaaggccgct tttttgcaga ctcctgaatc
     6781 ttttcgatta gtttttcgat tccttgcttt ttcaatacgc tgattggtaa aactggtaca
     6841 ccaagaccat aggaaagctt ttctagattg attttttttc cttctttttt gatgacatcc
     6901 atcatattca gaccaatgat cataggaatg tctaaatcca ataactgcgt agttaaataa
     6961 agatttcgtt ctaaattggt agcatcaata atgttgatga tcagttcagg ctgttcctga
     7021 accaaataat ctcttgcaat cacttcttct ggtgtataag gagacaaaga atagatgccg
     7081 ggtaggtcct gaatatgaat gttcggattt tttttcaacg atccttcttt tttttctact
     7141 gttacgcccg gccaattccc tacatattga ttcgaaccag tcaagagatt gaacaagcta
     7201 gttttcccgc tgtttggatt tccgactaac gcgatattca ttctttttcc tccctttgta
     7261 tcaagattag ttcggcctct gactttcgta acgtcagttc ataccctcgc actgtcagtt
     7321 cgattggatc tcccagaggg gctagttttc ggataactat ttttacattt cgcgtcaatc
     7381 ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg acgatcccag
     7441 tctctcctgc ttttaattga tcaagagaag tccagctttc agaggaagca gtctttttat
     7501 tgacaaagat ttgacctagt atttcccgac ttactgccac tcgatgactt tttaccagta
     7561 aaatggcatt gttgcctgat aaattgacga cgacgatttt acttccggca acgatcccga
     7621 tattttgcaa atggcgtttt gttttttctt ctgtttcgat tcgttcgact tgataaacga
     7681 aattctgctt tgcctgcgct aaggtctgca tattgattcc tctcttgtga aataaatcat
     7741 gtattaaaat cattcattat atgttctaat tttcttacgt gttacgcaaa taaatgagaa
     7801 tcattctcac atagaatact ctcggtaatt gagaatgtca attatacttg tgatattatg
     7861 agcgaatctt tagtattgat agataaaaat gagaaaaaaa tatttcttca tagttttcca
     7921 caattttttc tctattaaat ttgctatttt cccacacgat acttgttttc agctcttttt
     7981 tcaaaaacac aaaacttagt attccacagt ttccacaaca caatatgtag tgtttgttgt
     8041 ttgacttttt tactaagagt tttatactat ctattataga taataagaat gtgttagagg
     8101 aggcactcac catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa tgtaagatgg
     8161 tcaaacggtt tttaacagaa aatcaaattg cttttgaaga agtcaatatc gatgaacagc
     8221 ctgaagcagt agactggttg aaagcacaag gattccaaag tgttcctgtc attacttctg
     8281 atgcagaaac agttatcgga ttccgtcctg atcagttgcg taaacttgcc agctaacatg
     8341 actaaaagaa tcaaaacgtg atacatggat ttgaagggct tgagacagca ccagtttttg
     8401 tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat gcaatgattt gcaatcaagc
     8461 atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt tacaagatgt
     8521 cagttatttc aagctgaata atgaaatcaa tcggccagtc aatggtcaaa tccctttgaa
     8581 taaggataaa gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa atacgatgac
     8641 ttttccatct attatggaaa aaatcaatta cttgatcgat caagaatata tagaagcaga
     8701 attcattcaa ttgtattcac catcatttat tgaaaagcta tatcaatttt tggacgagca
     8761 acatttttct ttcaaatctt ttatggctgc ttacaaattt tattctcaat atgcgttgaa
     8821 aaccaacgac ggttccgctt atctggaaac ttatgaagat cgagtagcct tcaatgcgct
     8881 ttactttgcg aacggggatg aagaattagc acttgctctt gcagacgaaa tgatccatca
     8941 acgatatcag ccagctacac cttctttctt gaatgctgga cgtaaacgtc ggggcgaatt
     9001 ggtgtcttgt ttcttgactc aagtcactga cgatatgaac tctatcgggc gctcaatcaa
     9061 ctctgctttg caattgtccc gtattggtgg cggcgtaggg attactttat caaatcttcg
     9121 tgaagccggc gctcctatca aaggatatga gggtgctgca agtggtgtcg ttccagtcat
     9181 gaaattattc gaagatagtt tcagctattc taatcaatta ggtcagcgtc aaggagctgg
     9241 cgtggtttat ttgaacgttt tccatccaga cattattgct ttcctttcag caaaaaaaga
     9301 aaatgcagat gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg tacctgataa
     9361 attttatgaa ttgacacgta aaaacgaaga tatgtattta tttagtccat atagtgtcga
     9421 aaaagaatat ggtgtcccat tctcttatgt aaatattaca gctgagtatg atcatctagt
     9481 tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa atgaaatctc
     9541 aaaattacaa caagaatctg gctatcctta cgtaatcaat attgatacag cgaaccgcga
     9601 gaatccaatc gatggcaaga tcatcatgag taatttatgt tcagagattt tacaagttca
     9661 aacgccttct gtgattaacg gcaaacagga atatgaagta ttaggaacag atatctcatg
     9721 taacttaggc tcgacaaata tcgtgaattt gatgcaaagc cctaactttg gtcaatctgt
     9781 gcgtacgatg actcgtgcat tgacatttat tacagatgca tctgatatcg atgtcgtacc
     9841 accgatccaa aacggaaata agctgaatca tacgattgga ttaggtgcca tgggcttaca
     9901 cacttatctt gcaaaagaac aaatggaata tggctcagag gattcattag actttacaaa
     9961 tatttacttc atgctgttga attattggac acttgttgaa agcaacaata tcgctcgtga
    10021 aagaaaacaa gttttccata attttgaaaa atcagcttat gctgacggca cttatttcga
    10081 aaaatacgta actggagaat tccagccaaa atcagaaaaa gtcaaagcat tgtttgaagg
    10141 catttttatc ccaactgctg aagattggaa tgctttgaaa caagcagtaa tgaaagatgg
    10201 actgtatcat caaaatcgct tggcagtagc accaaatggc tcaatttcat atatcaacga
    10261 tacgagtgca agtattcatc ctatcactcg catgatcgaa gaacgccaag agaagaaaat
    10321 cggtaaaatt tattacccag cgccttatct atccaatgag acgattccgt attacacttc
    10381 tgcttatgat atggacatgc gtaaagtaat cgatgtttat gcaacggcac aacaacacgt
    10441 cgatcaaggc atgagtttga ctttattcat gcgttctgaa atcccagaag gcatttatga
    10501 atggaagaca acaacgaagc aaacgacacg tgatttgaat attttaagac attacgcttt
    10561 ccacaaagga atcaaatcca tttattacgt acgtaccttt actgatgatg cagaagaaat
    10621 cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat agatagattc gcttattcat
    10681 attttaatta aaggagcatt ctcatgtcag aaacatatta tgaagcaata aactggaatg
    10741 aaattgaaga tatcattgat aaatccactt gggagaagct gacagagcaa ttttggctag
    10801 atacacgtat cccactttca aatgacctag atgattggcg tacattgtct caattggaaa
    10861 aagatacagt aggacatgta tttggcggtt tgacactgct agatactgtc caatctgaaa
    10921 gtggcatgga tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc gttttgaaca
    10981 atattcaatt catggaatcc gttcatgcca aaagttattc ttctattttt agtacactga
    11041 atacgaaaaa agaaatcgaa gaaatttttg actggacaaa tacgaatcct tatctgcaaa
    11101 aaaaagctga gcgtatcaat gaaatctaca aacacggtac accgctagaa aagaaaattg
    11161 ccagcgtctt tttagaaaca ttcttgttct attcaggttt ttatactcct ctttattatt
    11221 taggaaacaa caaattggct aacgtagcag agatcatcaa actaatcatc cgagatgaat
    11281 ctgtacatgg aacctacatc ggttacaaat tccaattagg attcaacgag ttacctgaag
    11341 cagaacaaga aacgttaaaa gactggatgt acaatcttct ttatgagctt tacgaaaacg
    11401 aagaacgtta tacagaagaa ttatacgatc caatcggctg gacagaagaa gtcaagacat
    11461 tcctacgcta taatgccaac aaagcattga tgaacctagg gatggatcca ctctttccag
    11521 atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc acaagcaacc
    11581 atgacttctt ctcacaagtc ggaaacggct atttgttagg tcatgtagaa gcgatgaaag
    11641 acgacgatta tttgattgga ttggaataag gatttatttt aattcaaaaa tttttcgaaa
    11701 aataaaaaga gtttagcgta cagatatttt aaatgtacac tgaactcttt tttatgctta
    11761 ttcacttgtt tcttccagca cttttggact gtctaacttt tccgaaacat gttccattct
    11821 tctcaataaa tagattttcc ggatatttaa tattatcgtc ttaatcactg catagacagg
    11881 tatgcaaatc agcatgccta atattcctgc gacacttcct gctccaatca ataccaagat
    11941 gatcgtcaaa ggatggatat tcattgattt cccaaataac aacggcttga tcaaatttcc
    12001 atctaattgt tggatcacta aaatcgacaa cgccatatac aaagcttgaa atggagagat
    12061 aaacaaaccg acaatgattg ctggtaccgc tccaataaaa gggccgacat acgggataat
    12121 attcgtgatt ccgcaaatga ccgcaagcaa caagctataa ggctgatcga atattctcat
    12181 tgccaaaaag ctcattacac caataatcaa agcatctaag atcgtactgc tgatataggc
    12241 agataatgtt tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa tcgctttcgg
    12301 aaagaagtga gacaacgcat caataaattt gtgcccatcc ttgaacataa atagcaaaat
    12361 aaatggaacg gtaaataaca aaataaaaaa ttgcatcata aatgaaatga tttttgagac
    12421 acttgcagat aaactgacta atatgatatt gaacaaatta ctaagagata aatttgctga
    12481 tgctaattgt tcttccaaat tgaaattttt aaactcttcc cgctgcgcca attcatttaa
    12541 ccatttgctt gtttcatctg catacattgg caagctctgg gtcaattgaa ttgtctgttc
    12601 cattaactga ggcactacat tcatgacagt taaaacaact aaaatgatta cgaccaaaaa
    12661 cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa caacgattgg
    12721 atcgaacata taatagataa aaccagcaac aagcaatggt aaaaaaattg ccgaaagcat
    12781 tttcaatatt ggactaaaaa tattcggcat ttgtaaaata aagtacacgc cgatgatcgt
    12841 gagtactagc tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg attgcataca
    12901 tctcctccaa ggtcctttga tacttctatt ctatcattta acaaagagtt acgcgctgag
    12961 attttcattt gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt agacgagtac
    13021 ttaaacaaaa acacggtttg gagtagtgac aaaaattata ctgcagtccc tttttccaaa
    13081 taaacggtgt tcaaaagctt gcatcttcgt aataagccca gccaaacgaa aaatataagg
    13141 aactattttt atttggctgg gcttattact tgatgtagga catctatttt acaacctcag
    13201 atcatttatt gcgcaatact gactaaatgc aactttgtga tatttttgtg tacggacaac
    13261 tcctcgatca catcggcata agtgagccct tttggaagat caatcgtata gatatttttg
    13321 tacactcggt agtcatcaac gaattttacg tcaaaattca catcttcgat tacgatattt
    13381 ttctcttcaa aataatcggt aagaaaatct ttggtttctt ttctatggat aaattggatt
    13441 tctaactttt tagtcgtagg tacatggatc acgcgtttca ctactgtgag tgcaatagca
    13501 atcccgataa aactgatgat cgcaatggaa tagtaaccca tgccgatggc gatccctaat
    13561 ccagcaattg cccataaaga agcggcagtc gtaagtcccg tcaccgattg tttcgtgacg
    13621 atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat cagccttgct
    13681 tcatctgaac gaatcgttcc agcaagctgt ggatactcta aagcatctct taatgcacca
    13741 ctagcgatct caacttggat caatgcaatg atacatgctc ccatacaaac taaaatatgc
    13801 gtacgcatac ctgctggacg atttttatat tgtcgttcaa aaccgattgc tccgccaaat
    13861 agcatagcga tccctaaacg taaaataatc tctggaattg tcaataccat atcattcatc
    13921 taaacaccct ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa agtgcaattt
    13981 ttacctctta cgaaaaaagg actgtgacaa aatttttgtc atagtccttt ttatgaataa
    14041 acggtgttca atcagctgac cctcggtatt actcaacaaa cggcaaaata tggggagcta
    14101 tttttccttt gtcttctcta atactcaggt caaaacgctg atttcacaac ctctttagcc
    14161 tactattgaa aattacaact tacttgctgc ttcttcatcg atgatcacaa caacattgtc
    14221 gtgattttgc aatacacttg ctggcaaatg attcgttaca ggtccttcaa tcatcccttt
    14281 gattgcatca gctttgcttt cgccaaatgc catcaagacg atttctttac ttttcataat
    14341 tgaaccgatt cccattgaaa cagcttttgt tggtacatct tctgctttat cgaagaatcg
    14401 tttgtttgca ttgattgttg attctgttaa gtcaactact gaagtcgttc cgtcaaatga
    14461 agcaccaggt tcattgaaac cgatatgtcc attttgcccg attcctaaga tttggatatc
    14521 gattggatgt gcatcgatga tttgatcata ctttttgcat gctgcttcca gatcttctgc
    14581 ttttccatct ggtacaaacg tttctttgaa tggtttttta tcaaataatt ggacatccat
    14641 gaaatgacgg tagctttgtt catctgaacc gcctagtcca acgtactcat ctaagtttac
    14701 agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt tctttatata aagtaactgg
    14761 tgtgcttcct gttgccaatc ctaatacttt tgcacctttg ttcatacctt ctttgatgat
    14821 ttcaaatgct ttttttccgc cttcttcagc gttttttaca cgaatgattt ccatagtgat
    14881 tgctccttta tattttggta tagcccaatt atagcattct ttttttcttt ttacaataat
    14941 tagtatagac caaattgcat ttttttcatt ttcttgacaa taaataggaa tccgtgttag
    15001 gtttcataag atggttcaat caaacaatcc atgttgcatg aaaaccaagc aagtgattca
    15061 ctgtggacgc tttatgtctg cagttttttt atgaaaaagg agttattatg agtatactga
    15121 cattaaacaa cattacccag caatttggcg acaaaatcct ctatgaaggt gtcgatctgc
    15181 aattaaatgc tggcgaacat cttgggctga ttggacaaaa cggagccggt aaaagtacat
    15241 tgattaaaat catcactggt gagatcttac cagatgacgg acagatccat tggcaaaaaa
    15301 atattcacaa aggttacctc gatcaatatg tggaagtcga tgaaacatta acaatcgaag
    15361 aatttctaaa aactgcgtac gcaaaagaat acgaaaagga agaaaaaatt gcttttcttt
    15421 accaaacata tagcgagacc ttcgatgatt ccttgctgga aaaagctggg aaactccaaa
    15481 cggaattaga ccaaggagtg ttttatcaaa tcgacacctt agttgctgag atgagcagcg
    15541 ggttggggat cgatgtctta ggtttagatt cactgttgaa aaatctaagt ggtggacaac
    15601 gttcaaaggt gattttagca aaactacttt tagaaaaccc agatgttctg atcttagatg
    15661 aaccaaccaa tcacttagat gatcagcata tccaatggct gacgcagttt cttcaggatt
    15721 ttgacggtgc gtatatcgtg atttcccatg accaagaatt tcttgatcag atcaccaccc
    15781 atatcgcaga catcgagttt ggaaagatta ctaagtatac tggccatcta aaacaagcat
    15841 tgaaacaaaa ggaacaaaat cgcgaaagct atttgcgcca atatcatgct caacaaaaac
    15901 aaatcgaaaa gaccgaagct tatattcgaa aatacaaagc cggttcccga tcaacgatgg
    15961 caaaaagccg acaaaaacaa ttagataaaa tcgaacggct gacgcctcca gcttcagcaa
    16021 gtaaagctgt ctttgatttt ccattctcgc ctattgtcac gacattagca gtggaaacaa
    16081 ctgatttagt catcggatat gatcgaccgc tacttgcacc catcaatttg accatccgct
    16141 ttggtgaaaa tattgccatt cgaggcttca acgggattgg aaaatctact ttattaaaaa
    16201 cactgatcgg tgagattgaa aaaataagtg gcgatttcca cttcccagat aacacaaaaa
    16261 tcaattactt ttcacaagat ctgtactggg aaaatccatt agaaacacca ctacaatatt
    16321 taagcagtca atttccaaaa gcgactatca aagaattacg tcgccaacta gctaaagcag
    16381 ggttagttaa tcaattagca agtgaacctc tcactacatt aagtggtggg gaacaaacta
    16441 aggtgaaact tgcacagttg acaatgaacc aaggtaattt actgattctc gatgaaccga
    16501 cgaaccatat cgatcaagaa acgaaagaaa gcttacaaga cgggatacag aaatttccag
    16561 gaacagtaat catcgtctct catgaacaag aattttatca agatcttgtg caacgagtca
    16621 ttgagattga accaaaataa acgtttgatt gaatagttga aaaaaaggag ctgtgacaaa
    16681 agttttgtca caactccttc ttctgaataa atggtggcca attagctgac cttcggtatt
    16741 agctcaaaaa acggcaaaat atgaggagct atttttattt ggctattctt attacttgat
    16801 gcagaacagc ttttcacaac ctcttttcgt ctatttttta ttttcgagat ttctctttcc
    16861 tttaaaaaca actgtttgaa agaagaacgc acatccttga aaaacaagcc cgctaaccgt
    16921 tacacctaac cagccatact gctgccacat tgtcgtccct agcaatgaac cagccgcacc
    16981 tccaataaag tacataaaca taaataca
//
LOCUS       DAIGTA010000060        16855 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.063, whole genome shotgun sequence.
ACCESSION   DAIGTA010000060 DAIGTA010000000
VERSION     DAIGTA010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.063"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..832)
                     /locus_tag="NOB43_002172"
     CDS             complement(<1..832)
                     /locus_tag="NOB43_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0983014.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(846..1643)
                     /locus_tag="NOB43_002173"
     CDS             complement(846..1643)
                     /locus_tag="NOB43_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0983015.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(1676..1960)
                     /locus_tag="NOB43_002174"
     CDS             complement(1676..1960)
                     /locus_tag="NOB43_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCI0983016.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(1957..2958)
                     /locus_tag="NOB43_002175"
     CDS             complement(1957..2958)
                     /locus_tag="NOB43_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HCI0983017.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(2960..4027)
                     /gene="gnd"
                     /locus_tag="NOB43_002176"
     CDS             complement(2960..4027)
                     /gene="gnd"
                     /locus_tag="NOB43_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HCI0983018.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            4026..4874
                     /locus_tag="NOB43_002177"
     CDS             4026..4874
                     /locus_tag="NOB43_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0983019.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            5520..5726
                     /locus_tag="NOB43_002178"
     CDS             5520..5726
                     /locus_tag="NOB43_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HCI0983020.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(5928..6929)
                     /locus_tag="NOB43_002179"
     CDS             complement(5928..6929)
                     /locus_tag="NOB43_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0983021.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(6934..8846)
                     /locus_tag="NOB43_002180"
                     /pseudo
     CDS             complement(6934..8846)
                     /locus_tag="NOB43_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9014..9520)
                     /locus_tag="NOB43_002181"
     CDS             complement(9014..9520)
                     /locus_tag="NOB43_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0983022.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            9680..10120
                     /locus_tag="NOB43_002182"
     CDS             9680..10120
                     /locus_tag="NOB43_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI0983023.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(10146..11303)
                     /locus_tag="NOB43_002183"
     CDS             complement(10146..11303)
                     /locus_tag="NOB43_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983024.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(11306..11662)
                     /locus_tag="NOB43_002184"
     CDS             complement(11306..11662)
                     /locus_tag="NOB43_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983025.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(11960..12934)
                     /gene="sgrA"
                     /locus_tag="NOB43_002185"
     CDS             complement(11960..12934)
                     /gene="sgrA"
                     /locus_tag="NOB43_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HCI0983026.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(13130..13969)
                     /locus_tag="NOB43_002186"
     CDS             complement(13130..13969)
                     /locus_tag="NOB43_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0983027.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            14154..15041
                     /locus_tag="NOB43_002187"
     CDS             14154..15041
                     /locus_tag="NOB43_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI0983028.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(15635..16330)
                     /locus_tag="NOB43_002188"
     CDS             complement(15635..16330)
                     /locus_tag="NOB43_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCI0983029.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(16314..16712)
                     /locus_tag="NOB43_002189"
     CDS             complement(16314..16712)
                     /locus_tag="NOB43_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI0983030.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         5038 a         3423 c         2595 g         5799 t
ORIGIN      
        1 aaaatccgtc atcatagtca tcttcgtcat caaaagatgc tgaattgtta ttgcttgtgg
       61 caggctgtac ttgtttccct ttttgcgact ggacaaagat caaagcgata ataatcccaa
      121 aaatggcata agtaaccatc gtaatatcta aagatttcaa aacaacactc ataaaataag
      181 caaggaagaa aaagaccaga taatcttttc gaccgataac gtatacagtt gtcgcgatac
      241 cgattgccgc taaccctcca cctactactt caagaatgtg gataacgact gttccctcta
      301 aagctttgat tacatcagcg atcaatggcg cccctaaata taaagcaatg aaaacaagcg
      361 gaacgaataa taaaaatgag gcaaccgttg gataaagaat aattgatcgg gccatagctt
      421 ttgtattcaa atcttctaca gctttgtctg tatatttacc taaaaaagta ttgatgaaaa
      481 aacgaaactg atacaagtaa cttccgagca atccgactgg caccgcaacg gcaatcgctg
      541 cttctggcga cagatcccct aataatgcga ctggtactgc gatagctgct gcaatagatg
      601 gttcagctgg cattgatcct cctggagaaa aaacccccat ataaatcatt tgcaaagcgg
      661 ctgtaacaat catcgcttgt gcaacttccc ccatgatcaa cccgacgact aatccagtca
      721 tcaaaggaga aaaacgtaag gtcaacgtgg ctcctccacc taaccagcgg gacataaccg
      781 cggctaccca taaagcaatc aacaaacttt gtactacact taatgtttcc atgtgtcctc
      841 ctccttcaga tctttctgat ataaccttcc agttccatca ttgactgtat cagtgatttc
      901 tgtgttacct ctataggaat caaatgcact ttctctttcg aatcaataaa ttcagccatt
      961 ttatctatta tctgtttatc tttcggaaat aatcccattt gttctagaga aaccggcagt
     1021 tctaattccc gatacaaagg atataactcg tctatttttt cccagcgacc ttctagtgcc
     1081 agttgataga aaatcccata cgctactttt tctccatgta gaaaacgatg gctttccgga
     1141 atatatttac tgatagcgtc atgcatagca tgtgctgccg catttcttgc gtatttatct
     1201 cctaatcctc caactaaacc agcaacagca aagataatct ctgaaagctg tttgaactcc
     1261 gatgtcagtt ttctttgtgc catatcttgg attgctttag cagaatgatt caaaatctct
     1321 tctttgcaga tcttcgcagt atcttgtgct agcttcaaaa atgattcatc ttgcaaaaaa
     1381 tcttgttcta agatgagctc agattcatac cattttgcta gtgtatctgc taacccggca
     1441 atgaaatatg gaacagggga atcaatcact aattggggat ctgttataaa aaaagcagct
     1501 tgtctgtaaa agtgttctgt tttcccttct gcttgtccat tctccttata catgacagca
     1561 agaggtgtcc atggagcaca attactagct aaagtaggga tgactccgaa atcgattctt
     1621 gcaagattgg cactataacc cactagatcg gtcagttttc ctccgccaac gccaactacg
     1681 aaatcgattt catttttttg atgattgtag ctattcgtct ggcttcagca taactacatt
     1741 ctccagaata acgatgataa aaaaattgaa tcgtttcgtc attcaaaaat actaatttag
     1801 gtagcgcctt ttcccatgat accgttccgt gggtgaccag tactcttttc gcgccgtatg
     1861 atttcaagag atcagaaact tttgaaatac caccttcttc atataaataa aattgagggc
     1921 ctgttttcac ttttaaaccg ttcaccattt tcttcatcat ccttttatat agttgctctt
     1981 tgtctggaca gaacgttcag gaagaaggtg ctgactgatc tgttcgacat ctctgacaca
     2041 tttttcaccc attgcttcta aacattccct tgtgtaggcc gatatatgtg gcgtaatcac
     2101 tacttgttca aacgctaaat acggatgatc ttgacgtccc ggttcttctt ctaaaacatc
     2161 tgtggcatat cctgcgatct ttccgctttt cagaccatta atcatcgctt cttcatcaac
     2221 tagagcgcct cttgcactat tagatagata aacattttct ttcatctgat cgacttcttt
     2281 atcagaaatc atgtgatagt tctcttctgt caaattcgca cataaacaaa tgatatctga
     2341 ttgttccagt aattcttgaa gttctacttt ttttgcacca aagctttcga tgtataaatc
     2401 tgatttgtaa ggatcataag ctagaacatc acagcgaaaa ccgttacgca aaatttcgat
     2461 tactccgctt ccggtatttc ctgcaccaat cacaccaact gttttgttaa acagcgtcct
     2521 accgacgaac tccgcccgat cttcccatcg atcgtccttg actcttgctt gtgcttgtgt
     2581 cgtgcgtcga agcatggaca acaaattagt tatattattt tctgctacag catttcgttc
     2641 aactaaagca ggtatgatag atacgattgt ctggtgttct tttgctgctt ttaaatcaat
     2701 attgttgtaa ccaataccat gtcgggaaat caatagcagt tcatctttgt tttcaaaaaa
     2761 atctcgtcga aaaaatggcg taacacttgc aataatgata ttgaatcctt taagtaactc
     2821 cgctagttct tttcctggaa tctcttgatc aacagtaaag aaatgaacgt ctccaactga
     2881 ctttaatctt tccaagtggt gtggaaagac tcttccgaaa ctgctggaat taacgattgc
     2941 tatatgataa tctggcattt tactcaccct tttcaactat ttcatgtccg ccaaacccat
     3001 ttcttagtgc tgaaactact tttgctgaaa aactatcttc ttcctgtgaa agattcctca
     3061 tgaacaaact agttgcaatt actggaactg gaacagccat ttctagcgct gtttcaaccg
     3121 tccattttgc ttcacctgat gcagaaacga ttccccgata attacttaaa ttgggatgtt
     3181 cgtttaactg atcttccatg atttccatca gccagccgcg aatcaccgaa ccatgattcc
     3241 aaacacgtgc gacttgttcc aagtcaaaag catactcact tttttgtaca agttggaatc
     3301 cttcaccgat tgcttgcatc attccatatt cgattccatt atggatcatt ttcaagaagt
     3361 gtccgcttcc ggatgcacca gcatacagat atcctctttc aattgctaca tctttgaata
     3421 attgttccac ggatagaaaa gtttctttat ctcctccaat cattaagcag gcttgatgtc
     3481 gtgctccttc gattcctcca gaagtcccac aatccaagta accgatttca tttttctgaa
     3541 actcttctgc tcgacggatt gaatctttat aataagagtt tccgccttca ataataatgt
     3601 ctcctggtcc gagttttgga aaaagttttc ttaacatgtt ttcggttatc tctccagcag
     3661 gaagcattaa ccagatgatt tttttctgct caaaagtagc tagaaattca gagatctctt
     3721 gataagcagg aatgtcattt tctcttgcct gactaacagc tgtacttgaa atgtcgagtc
     3781 cttgtacttt gtgatggtgc tcttttaagt ttaaagctaa attcaatccc atttttccca
     3841 aaccaattac accaatttcc atgatagcgc ctccatttct tataccctca ttatacaaaa
     3901 aaattttttt gtaaatagat tttacaaaaa tattttttgt ttgatttttt cctactctcc
     3961 ttgtatcttt aacattaatg agaacggaaa aaatgataat cttattatga aaatgaggaa
     4021 ttctcatgag cgtctccata agactacaaa tcaaaacaat gtacaacgac ttcagcccaa
     4081 aagaacaggc tatcgccgat tatattttag aaaatccaag caaagtaagt catagtccta
     4141 ttagcaattt agcaagtgaa ctgggcattg ctgactctac tttttttcaa tttacaaaaa
     4201 aacttggtta taatggattt aaagatttta aaatggccat gttgatccaa gaaaatgatc
     4261 tatctgctat ttctatccac gaaaatattc agaaaacaga tactgagctc actatggcgc
     4321 aaaaggtgtt cgagtctagt atttcaactt taaatgacac aaaaaagttg ttacaacaaa
     4381 aggatctaaa aaaagcggct actattatca atgaatctaa acgtgtctat tttttcggtg
     4441 ttggcggttc agagattgta gcaactgacg cttatcataa atttttgcgt tcccctatcg
     4501 caacttctca cagcacggat taccatattc aattgatgga agcttcttta ttgacggaaa
     4561 aagactgtgc tgttttgatt tctcacacag ggcaatcaaa agaaacaatc catattgctg
     4621 aaaccgtaag aaaaactgga gcaaaaacaa tcgttattac tagccaagct aattcttccc
     4681 ttgctaaact tggcgatgtc gtttttattt ctatttctga agaaacagaa ttccgatctg
     4741 aagctttagc ttcccgtatt tctcaactaa gcattttgga ctctctatat gtgattttga
     4801 tgttttacaa cgaaaaagaa tcacgtcgtt ctatcgctaa agttcgacat actatttctg
     4861 aaatcaaaga atagcaccat aacagaaaaa gcgaaaaatc cataaaacaa aaaaagccac
     4921 taccaaatat ttggtagtgg cttttttggt tctgcaaggg tggtacagaa catcaatagt
     4981 cggtgggtta gaacgtatgt catcgcatct ttggagaagg ttgtattggt attattcgag
     5041 ttacttgtta gatgcgataa caaagttagt atacagtagt aaaaaattta tcttttcttt
     5101 tttttattat ttttgtttct tattttctaa aaaattaaaa aaaattttgg tgaattaagt
     5161 atttccttga taacactggc ttttggcctc attttaggtt atcatttgta attttatttc
     5221 acagttgata tgattgttat gtaaaataaa aaagtttagg atacatcgaa tttttgggga
     5281 aattcttttg ggggtatcct aaatcttttc tattatattc ccatattttc tattattggt
     5341 ctagacgtat gatggtaaac tttgtaccta tctgattgct gaatcattaa ttgcttatca
     5401 ttagccatct ttgtttcaag ttcgctagat gatcatttta ttcacatcct aacaaacttg
     5461 tcacatttat agattcttaa tctatttatc atacaattat aaaaaaggag gtgctgctta
     5521 tgaaagctat ccatatttct ttgctttttt tcgctagtgc attgatttta tttgctattc
     5581 atctttgttc ccagccttat atcaataaca acggaatatt agtggaacca gcattctttt
     5641 gcttaccact cggctttttg tcccttcttg cctccgcagg cttcggattt gttgcttttt
     5701 ttaaacgatc aaaacaacaa atctgactta taaaatttac gtaaaagaga tcgtgacaat
     5761 aatcgtgtga tattcccaaa tttcgaataa aaggtgcccc ttgccatctc taactcctca
     5821 gtcacaagtt acaatattca taaaccatga aaagcttgtt tattgaaatt gctccttgtg
     5881 acttggagct aagtgacaga ttacaacctc ttttgcatca taagacttta ctccttgaaa
     5941 aacattacta acttttgata tgtttcttgc gcttgtttat tgctgaaatc aaactgatat
     6001 tcatggttca aaacagcatt tttctccgca taatctactt ttgtgacttt cacccccgct
     6061 ttctcaaata cagaagttac ttcttccatt tgtttcgtaa acgtatttgt atttccatcc
     6121 gttaagaatg tgttttgcgt ccaacgatcc gcatgtctga ccaaggctaa acttttgacc
     6181 ttctctgatt gttcaaagtc cttattatca aagtaagccc atccacattt ttcataaaga
     6241 aagctagaga ttttatcact tacttgagta agtgcagaag gatccaacag accagacaaa
     6301 gaaataaact tcgtaatctg cttgttctcc aaagtcggat caagatgatc agctttttta
     6361 atttcttcat tttgaagtgc taacaaatat tctccactaa tttgtgcacc tgccgaattt
     6421 ccaccaatcg aaatattcga ccaatctgct tgatctttta tctctttttt agctgcttga
     6481 atggcttcgt tcaattggat aactggtgta ggatgttttg cttccggtga tcgttcataa
     6541 tctatattta cgatgatttg ctgcgtgtct gaacatagat attccaaata atcacgacaa
     6601 tcatttttat cccctcctac atatgcgcct ccatgcatcc agaaaagaat cggtaatttt
     6661 ttcttttcca ctttcggtgt gtagatatcc atattattat ttttgtactt tgaaggatag
     6721 gatatttctt tttttatatc gatttgttcg attttttgct ggaaatcatc tggtcgggca
     6781 tatacttgtt ctttttcact tgtgtcaaat tgttttctaa caagcaagct aatcggcttt
     6841 ggtgtgattt gattaatcaa aaatacagtg actaaaataa ctacgatgat aactggtact
     6901 gcaatcacta ttcgcttgaa ccatttcatt catttaccct ctctttcttc gccaaatcca
     6961 tgtgataatc gtgctaacag ataaaaatcc acctgaataa atgagaagcg aatgtttctt
     7021 ttctccagtt ttcggcaaca ttcttttttt gcatctgtct ttttttgtac tttcactgtc
     7081 atctgaatcg gttgcgtatc atcacttgat tgatcctctc gaggttcatt ctttccctta
     7141 ttgtctgcat tctctgtcgg atcttgcttt tttggtggag ctactgggat ttttttgtaa
     7201 tagaaaataa tagttggtat cgtctcatta aaaatccctt cagtcggtcc ttcaacattt
     7261 gctaattcgt atccttcgaa tgtcttttgc tctgtcatat aattttctcc ataagctccg
     7321 taaagctgga tttcgtcctg gtctttgagt agacttttat tgttttcatc cacatacttt
     7381 acgtttatct gatcatggaa cactactttc aaaaagtccg ttacatgttt cgtgtaggca
     7441 gcatggtcaa cttcctgtgc ctttccatgc cctgctcctt ctactaataa aagatcttta
     7501 taccctcctg ataactcata taatttttgc gcgttagaca caggtactac atcatctgct
     7561 gttccatgga taatcaattt aggcaatgaa tctgacattc caatcgtagg tagagcagct
     7621 tttgtatcca aatgcatctc ctgatcaaaa tagtattgtt tcaaaaggcc cataaataaa
     7681 tcttcatgct cttgatcccc aatgatgtct aactgatttt ttatggcatc cggtagtgcg
     7741 ggggctactg tctggctgta cgtaaaacgt agttgttcat caattgatgc aaatccgcaa
     7801 ttttcaataa ttcctttgac attgacagga atatctttcg ctaatacaga catcatcgta
     7861 gctgctccca tcgaaccacc ataaagtaaa atcttttgag atggccgctc tcgaacttct
     7921 tgatttatcc agtaaaggac gtcatctgac tcatattgtc cataggtcac ataatcgcct
     7981 ccgctattac cagtcgctct ggaatcaaca aataataaat tatacccggc cttataaaaa
     8041 tcattgtatt cttctgtaac gatcccgtta ttccaattcc ctcgaaatcc gccatggatc
     8101 atgactgttt tatctgaacc ttgatcgaca taatatgcat atacatccat cattttgcca
     8161 tcttgtttgt ttagtacagt ttgatgaagt tgttttgtat ttggatagaa gcctgtgttt
     8221 tctgtaggcg ttgtcccatc atctgtacct ccaagcatcg acatcaacac actgtttttt
     8281 gcaaaagcga tatcgtacaa tagataagta gcaatcagat gtttgataat ctctttatct
     8341 acaccataat cattaacagc aagctcagtg actaataact ctattaattt tgacttgatg
     8401 tcttctgttg gtccattaag tatttctgtc atctgtttac cgaagtaatt caaatattct
     8461 ttaccattga aattttcacc tttaccgata tcatcatttt ctgtcccatt ctctttgtca
     8521 cttactttag cagaagagga ttcgtcgttt gacatttttg tagctgttgc ttcttctgtt
     8581 tgttggttat ctgtggtagc ggtcgtttct tgatctgtgc tagtaacaga tgtctcaacc
     8641 gttgtttcag tatttgtttc tgtttgtgaa gtactcgatt tcgtttcatt tccagcatca
     8701 gtagtttctg tggtttctac ctcccgagat tccgattcgg aagaaatgct ctctccatat
     8761 actgtccatt gcgggacgct tgtacttaca gcaaataaga tgaccaacgc tccctttaat
     8821 acttgttttg ttctcaagct attcactcct ttttatgttt ctaggagaat tatatgtaaa
     8881 cgcaaacatt ttttatacaa aaaataaatg gtttatccca taaaaataga acaggattat
     8941 tttctcattt tacgtaataa agcagaatgg ataaaccagt atccattctg ctttttttaa
     9001 acgaagaaac aacttattgc tccaaaaatg tcagaaatcg tttatcccaa attttctcgt
     9061 aaaaagcgat tgtttccttt gctttcataa aaggattatc ataagttgtc gttgctcctc
     9121 tacacatcat aagctggtat cctaatccat gagcaaactt cacagtcgta tctatacaat
     9181 actctgcttg tgccccacat aattcgatcg aatgacagtc caattcagtt aataaaacac
     9241 tcaaattagt cttataaaat gaattcgcat gggtttttct cacaaaataa ctgtgctcag
     9301 gaatagataa ttccgacaat agctcccatg gttttgtttg tggcactaat tgagcatctt
     9361 cgtgttgaac gaaaataact ggtttcccaa tcgtttcgta tgttttgatt cttttattca
     9421 ctaatgctgt cactgtttct aattcgtgta tcggcgaaga atcaaaacat accccttttt
     9481 gtaaatcgat cactactatt gcgtcggctg tgtttgacat acttgtgcct tctttctttt
     9541 ttcttgattt aatagtattt cttatctagc tagttccatt atacgtgaca acattttctt
     9601 attttacacc tctaaatggc acttttcgac tatttcttca tgttattatt tcataaatac
     9661 ttagctattg gaggaatgta tgatgattaa attgtataca ggttctggct gctcgtcttc
     9721 aagacgcgca aaacgttggc ttatcgtcca tgatataccg tttatcgaac agaacttaat
     9781 tcgtcaacca ctaaccaaaa atgaatttat ccacttacta aaattgacaa acaacggcgt
     9841 gaccgaaatg ctctctactc attctattag ttataaaaat cttgttcaca gaatagatga
     9901 actcagtttg agtgaactat atattgagat tcgtacatcc ccttctttat tgaaaaaacc
     9961 gattatctac gaccaatctg caaaactttt gactggattt agcgaagata aaatcaggat
    10021 gttcctttct aaaactaaaa gaaagcaaga gctcaacgaa ctcttgcttt ctggtcatct
    10081 tgtcgatttt aaagaaaata atctttttgc aatgtcttaa ttttggcata aacaatctgc
    10141 ttttcttaat taacgaaatc caatttttcc aatatggatc tatttttctc attcctgatt
    10201 tttatgattt cagctttcag acgcgcccaa tcattttttg taggttgtcc attccagtaa
    10261 aatatctgtg tattcgtttg atcatatgcc tttttgtcga taggataatc gctaatgaca
    10321 atatcaggta actgatcagc ggatgcacta tattttattg ggcgttcagt catagataat
    10381 atccttttct ttgcccataa ttcctgtgtt ttaccatact ttgattgaat atagaatatg
    10441 acaggttgtt cgtgttttat aaaaatatcc ctgactaaca tacagtattg aaaaatcaac
    10501 cgtctgttct tttcataata agtattaagc tctggaattc tgcgagctac cccactaaaa
    10561 aactgttgca tgattggata catcactgga aatatatgct gaaaatctct gtcttctgct
    10621 gattttccaa aagcatccac cttctttttt gtcccaaaaa cccttgaata caaatggatc
    10681 attgccaaat tgacatatag ataatttttt tctgaagttg taaaacaaat cttgaagttt
    10741 ttttcaaaat tttctacaat agacgattca atccagcccc aactttcttg tactttatct
    10801 ggagtatcca acaaatcttc ttccaaatag gtgttcatta caccaaacat aaaataaagg
    10861 taagcttgct ctgttggagt gatgtgattc atcgaccaga agtttgcttc aaaaaaaggc
    10921 tctagtatgt aatgcgtaaa ctcttctttt gttatcaatg gatgcacaaa tttgttcatc
    10981 tcttctggga catacgtaat cgagtggcct tgtttcattc gttgcaacga aattcttagt
    11041 aggctgatcc atttctttct atctatacta cgcgtatatg gcgcatgttt cgcaaatttt
    11101 tctaatagtt gacgtttatt ttttatactt gataatatat cagaatgatt ttcgtcgaat
    11161 gactgccaat acatcaagtg aaaaaagtat cggatacggt attcttctcc ttctatcgga
    11221 ttaccttttt tcaagctgca agataaatga tagtttttca aaatagtatt aagttctctt
    11281 aattttcttt gaatcgtacg caaacttata taattttttg actaagattt tctaaggatt
    11341 gataagtacc tttgtaaagt gaatccagta aaatataacc aatcgttccc tctaaaagta
    11401 tagaataaac tttactcagt aaaaactgag aagaaaactc gacttttatc atcttgtttt
    11461 ctgaaagaaa agataattta tattctggat acctttcgca aaacgattct gcttgttgaa
    11521 tcaccgaatt catcttagcc agggtgtagt ttagatctaa agcgatatcc ttcaccacat
    11581 ataatttctc gtctctttca taacaatagt tcaaaaattg atatacttgc ctttcattga
    11641 tatcaataaa ttcttcaaac aaagtacata ctccttttta tctattattt agacttattc
    11701 cgacagctac atgaataacg tacaaataga ttcgttactg atttttcaga gatactacca
    11761 tgcgcagtgt gcattgtcaa ttattcttgc tcttattttc catttgtgtt cctgttattt
    11821 cctgtttctc aaatatgtta gtaaacaaaa atagatctgg caaagctaca acttcgccag
    11881 gcaatacagc actctcgaat gaaatattca ctcaaaaatc tatcgtttta ttcaatttta
    11941 gatctgttgc ttttattctt tatttcactc gatggaagag agaacgaaaa tagcttgctc
    12001 ctacaatcaa aatgagtaac acacccatcc atgtaattag cttgttcaag gttctactac
    12061 cagtttctgg taaatcgctt tttctattat ctgtttcttt cgctttttct tgatgatcaa
    12121 ttccacgaga aacaaaatca ggctgtttta gcacactttt taggttgctc cctgcatttc
    12181 tcttttgttc cttagttggt atgataggta ccaaatcaag ttcattattt acttttcctg
    12241 tgctgctttc gctgctcgtg cttcctgtgc tactctcact actcatgctt cctgtgctac
    12301 tttcactact cgtactctcc gtactgcttt cgctgctcgt gcttcctgtg ctactttcac
    12361 tactcgtact ctccgtactg ctttcgctgc tcgtgttttc tgtgctactt tcactgctcg
    12421 tactctctgt actgctttca ccgctcgtgt tttctgtact gctttcacta cttgtgctat
    12481 ccgtactgct tggcggtcca acaactgtcc aactgcttgg tttcaaattc tccgtgatcg
    12541 tcatctgtcc atcataaaaa acaatcaaat caactttatc tttactcttg atctcatcaa
    12601 tcgatagttc tgcagaaatc attattgtat actcaatacc agcggtccat tgtacgtctt
    12661 ttaaataaac ttccccaata actttttctg aacttccatt accatcccaa ccatatgtta
    12721 gaacagcatg tacatcacta gcattcacgc ttttgtttgg tttgactgga atagtaatga
    12781 cttgttgtgt catgtcataa acaatccgat cagttttcac agtaaatgaa agattctcat
    12841 ttgcccgttc atttgcagaa gtactgattc caatcattgc tgcaattata ctcagcccaa
    12901 gaataacaaa taatacggtc gctgttttct tcatttctat cactctccat ataattacct
    12961 tctatttgat aaaggaatta tataaaatga aaatgatgag aacacgacag tcagttgtga
    13021 aaatctaaca aaagatgtcg tgtattcgct tgaatttgtt tactttttcg tttaatcaat
    13081 gacagactta aaaaagcaag accgatatca gccttgcttt cttcatcttt tattgataaa
    13141 cagcagtgta tttcttcatc cgctttgttt tatatgcata gagtaacaaa ccaacaatca
    13201 agactaacaa gaataatgta gttgatatag atgcttcagc cccaaagttt cccccagtaa
    13261 ttattgtatt ttgcgattgg atcagagtgg agaaaaaacc ttgttcttgc gttccgctga
    13321 ctggtatacc caaaatagct ccttgtgtcc aattccaagt aatatgagca ccaatagccg
    13381 taaataaact tcctgtactg tagataagtg cgctgaaaaa gcaacctgct aaaaagatat
    13441 tgaaaactgc cagaaatgtc atgttaggat tcaatccgtg caaaagagca aataatgcag
    13501 cagatccaat cattgctatt aacggaccaa atctaagcat ctgatgctga aaaaagccac
    13561 ggaataaaag ctcttctgat gcccccactg caataaataa aataaaactc gttatcagcg
    13621 gcacaatgtt tgcgtttcct gaatctaacc gatacgcccc cgtcaaatat aatggactag
    13681 taataagcag aaacactcca attccaacaa cgagacctcc cgctaaatac ccccagtctt
    13741 ttcctcgaac agaaacacca taatcttcta ttctttttcc ttcgacctta ctagcaagaa
    13801 ataaagctag taaaaaaaca gctaaatgtc cgaccgtacc ggcaattgct ccaatccatt
    13861 cactatttcc aataaacata tccgcaagtg cattattgac aagaattcct aaaacaaaac
    13921 caactaagac tattaaaaca gatccaatca accgaataat cctgatcatc tttcatccct
    13981 cctttatatt aagtttaaca acccttttct ttcttgtctc gtgaaaacta tgtaaatgtt
    14041 ctccatcata gagagaatag atttttacga actaagaata tctacagcaa ccttacgaaa
    14101 atgaaagact gtctccctaa ttcttctgtt agactgtttt taataaggaa aggatgggaa
    14161 attttttgaa aaaacaacta cttattatgt gcctttcagc atgtgcaatt ttactattct
    14221 caggttgtag caagtccaat gaaacgattg caacgtttaa aggtggaaca cttacagttc
    14281 aggattttta tgataaccca aaagttaaat caaataatca aacactatta aaaaaaatga
    14341 ttgtcttcaa agcatttgat gatgtatacg gaaaagagat ttcttcaaag gaagtaacaa
    14401 aagaatataa tgaacaaatc aaaaaactcg gtccaaacta caaggaacaa ttaaaagcag
    14461 ttggccaaac agaagagaca tataagaaac tctttaaaca gatgctggct ttccaatacg
    14521 gtttgaaagc caatgtaaaa ttaacagata aagatctaga cactgcttgg aaagaattct
    14581 atccagaagt tagtacacag atcattctat tttcgactaa agaagaagca gataaagcaa
    14641 aaaaagaagc aaatgaagga gaaaatttct ccaagcttgt tcaagcttat ggaaaaaata
    14701 aaacattaaa ggaaactgat ggaaaaatga attttgattc aaccaatcca gagattccta
    14761 ctgaagtaaa aaaagcagca tttaaactaa aaaacgggga agtttctgat atcattcctg
    14821 taacagatcc aacgacttat cagcaaagct attatctagt aaaaatggta aaaaaacagg
    14881 ataaaggttc taataaagac aaatacaaat ctgagctaga aaaaattgct accgaagcaa
    14941 aaactcttga tacggaattc atggataaaa caatccgtaa agtgatgaaa aaagacaatg
    15001 taactattaa agatccttat gtaaaaaata tattcaaata aacaaatttg acccaattgg
    15061 ggatgtggca aaatttgaga agtgattttt ggaaattcct tcttattttt gaggcaaacc
    15121 acttttgcca caacttcatc ggggcctttt tttatttgta ccaaaacaaa tcactggatt
    15181 tgttacaatc atgaggatat aatttaaaaa agttttttat ttctatcaca tgaatcaatg
    15241 cgccattaag tagattcttt catgcttccc tattttttca cttgccgtat cgcttcaaaa
    15301 acaactatca taaactcaaa ctcgactgaa aagttatttt aaaaaagact aaaaatatcc
    15361 cttctggact tgttcttctt attctgttat actagagaaa cacgaaagat atttttatgc
    15421 gacacttttc atttgttttt atgaaattta ttcaaaactg gcgtaacttc agagttacaa
    15481 ggatgtatta gaggttaggg aatacatcgt ttaaatgaga aataagtaat agttagtaat
    15541 agtcacccaa actttaaatt aatgaatatt gaatcgtcag atagcctcct cgagttttcg
    15601 agaaggctat cgtttatttt atggagaaat tgattcagaa gtaatcagcg acctttttta
    15661 gttcaccaat cgtttctgct tggaaagttt gcacccaatc ttcttggaag cccctcactg
    15721 ctttatcaat cgagggcatc tctaatactt gatctagtag ctctttacct aacgttatcg
    15781 catgagctcc agatcgaatg gctgtagtga cttgttcaca atttttgaaa ctagctgcta
    15841 atatttttgt tggtctttgc gtacgttcga tctcagtccg caacgaatca atcactttca
    15901 tagcatcaat gccttgattt tgcatcctgt tataataagg tgcaatataa tctgctccat
    15961 tattaatagc taaataccct tgtaattctg tgtaaatagc tgtaccggta atcaaataac
    16021 cttctttttt caactttttg atcgcttgaa ggcctgcttg attcaccggc accttgataa
    16081 acgtatcttt tcccagttct tctatgataa ctcgagcatc ctctatcatt tcttcttccg
    16141 ttcttcctat tgtctgaata tggataggaa tctgtccgat tatttttttg atttctttca
    16201 tatgcgagaa gaagtttgac gctccttctt ttttcagaat tgtaggattt gttgttacgc
    16261 ctgttaaatt caaaaactgt tgacaagaat aaatactttt tgtatttgct gtatcaagca
    16321 tgatttccat atagctttcc cccattctga tcctcttgat cgattttaat gattgtcccc
    16381 tttcttaaat gcggcatttc cttatcttct acatacattg ttcctggaag ttccggctca
    16441 tgagatccat caaattttat cgtgatatgt cctaattcat tcaaattagt ttggacaaca
    16501 tctcctactg ctgtgattac atacatttgt ttatcaaaac agagcttcat atcacaagtt
    16561 atttcttttc ttacctgatt caattcaatc ttataacaat aatctgttaa tgtttccggt
    16621 gcttcatctc caaataaaat cattattttt tctttcctga atacttctgc ttctatacca
    16681 acatctgtta caaccgtttc aaagatcgtc atctctgttc ctcctcgtaa aatatcattt
    16741 gtctaatagt ttttattcaa aatgtttcta gattataaaa tttattgaat aacacattcc
    16801 taacggaatt tgtttcgata ttgtgtgatt tctcagagta caatggatgt atgga
//
LOCUS       DAIGTA010000061        15480 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.064, whole genome shotgun sequence.
ACCESSION   DAIGTA010000061 DAIGTA010000000
VERSION     DAIGTA010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.064"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..1199
                     /locus_tag="NOB43_002190"
     CDS             <1..1199
                     /locus_tag="NOB43_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI0983031.1"
                     /translation="IASNIRAIYVDEFQDTRELQYNVIAKLLQNNPQIQSMFVGDIDQ
                     AIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCYRSNQRLVDFYSNFQSCPYEIESRGN
                     NKNDRGFISYDCKVTKEDLPNIIKNIIKEKIESGIHEKDICVLAPQHYPLFSLGEYLK
                     KELPYCNFDAINISPIKVNNHSLFFKLAILYFTESGEKVRRRKLIANDILIILKNEFG
                     IEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLYKFVTKHIFVNLNIDEKNYPSIFKHY
                     LFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGITLTTAHKVKGNEYDTVIAINLLNGK
                     IPHWNEIFNVSDKGISSARKLLYVICSRAKNNLFLFSEVGYFTSKGDLLYPTQLLDKI
                     EFDYNI"
     gene            1399..1713
                     /locus_tag="NOB43_002191"
     CDS             1399..1713
                     /locus_tag="NOB43_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0983032.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            1734..2111
                     /locus_tag="NOB43_002192"
     CDS             1734..2111
                     /locus_tag="NOB43_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0983033.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            2121..2894
                     /locus_tag="NOB43_002193"
     CDS             2121..2894
                     /locus_tag="NOB43_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983034.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            2916..4319
                     /locus_tag="NOB43_002194"
     CDS             2916..4319
                     /locus_tag="NOB43_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCI0983035.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            4501..5685
                     /locus_tag="NOB43_002195"
     CDS             4501..5685
                     /locus_tag="NOB43_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0983036.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            5682..5972
                     /locus_tag="NOB43_002196"
     CDS             5682..5972
                     /locus_tag="NOB43_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983037.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            5969..6190
                     /locus_tag="NOB43_002197"
     CDS             5969..6190
                     /locus_tag="NOB43_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983038.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            6232..7011
                     /locus_tag="NOB43_002198"
     CDS             6232..7011
                     /locus_tag="NOB43_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HCI0983039.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            7078..7572
                     /locus_tag="NOB43_002199"
     CDS             7078..7572
                     /locus_tag="NOB43_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCI0983040.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            7628..8266
                     /locus_tag="NOB43_002200"
     CDS             7628..8266
                     /locus_tag="NOB43_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983041.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            8338..8733
                     /locus_tag="NOB43_002201"
     CDS             8338..8733
                     /locus_tag="NOB43_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0983042.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            8717..11170
                     /locus_tag="NOB43_002202"
     CDS             8717..11170
                     /locus_tag="NOB43_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0983043.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            11167..13194
                     /locus_tag="NOB43_002203"
     CDS             11167..13194
                     /locus_tag="NOB43_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983044.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            13191..14213
                     /locus_tag="NOB43_002204"
     CDS             13191..14213
                     /locus_tag="NOB43_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCI0983045.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            14230..15159
                     /locus_tag="NOB43_002205"
     CDS             14230..15159
                     /locus_tag="NOB43_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0983046.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            15404..>15480
                     /locus_tag="NOB43_002206"
     CDS             15404..>15480
                     /locus_tag="NOB43_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="regulates the transcription of tet(M) by
                     attenuation; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCI0983047.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDK"
BASE COUNT         5284 a         2562 c         3045 g         4589 t
ORIGIN      
        1 atattgctag taatataagg gcgatttatg tggatgaatt tcaagatact agagaattac
       61 aatacaatgt aatagctaaa ttacttcaaa acaaccctca aattcagtca atgtttgttg
      121 gagatattga ccaagcaatt tatggatcat tagatggtat agctaaatca gttgaagaac
      181 tagaaatgct aactagtcac acttttcaat caaagacgct acatggctgt tacaggtcta
      241 atcagagatt agtagacttc tactctaatt ttcagagttg tccttacgag attgaaagca
      301 gagggaataa taaaaacgac cgtggtttta taagttatga ttgcaaagtt actaaggagg
      361 atttacccaa cataataaaa aatataataa aggaaaagat tgaaagcggc attcatgaaa
      421 aagatatttg tgtacttgct cctcaacact atcctctgtt ttcactgggt gagtatttaa
      481 agaaagaatt accgtattgc aattttgatg ctataaatat atcaccaatt aaggtaaata
      541 atcatagttt atttttcaag ttagcaattt tgtactttac tgaatcaggt gaaaaggttc
      601 gaagaagaaa gctaattgca aacgatattt taattatatt aaaaaatgaa tttggaatag
      661 aagttaaaga ttattttatt gacttagatt tattacagct aataaacagt gtgaaaagaa
      721 tgtatagtgg agacgacaac ggtgttgatt tatacaaatt tgttaccaaa catatatttg
      781 ttaatcttaa tattgacgag aaaaattacc cgtctatttt taagcactat ctatttttta
      841 ttaacgaagt agaagatcgg ataaaaaata attcattatc tagtagtgta tctagtttta
      901 agaagatgtt taaatctcga gatggtatca cacttactac agcacataaa gttaaaggaa
      961 atgagtatga tactgttatc gctattaatc ttctaaacgg gaaaattcct cattggaatg
     1021 aaatttttaa tgtttctgat aaaggaatta gttcagcgag aaaactacta tacgtaattt
     1081 gttcaagagc aaaaaataat ttatttcttt tctcagaggt gggttatttt acgagtaaag
     1141 gagacttgct ttatcccact caattattag ataaaataga atttgattat aatatttaaa
     1201 atacctaggt agtcgttgtt ttaaatatag taggaatcgg acgctcagta cggagcgtct
     1261 atttttttac ccaattttga aaggaagtga acttatgaaa ataaaaaatc aagaatcaaa
     1321 aggtcgctct ccccccttta aaaccatcac acaaataaga ttcattcaaa cataaaaaca
     1381 gaaaggatag gtaaaaatat ggaacttaaa tatgtcattc ccaatatgga aaaaacattt
     1441 ggacaattag aatatgctgg tgaagggaac attgaacaac gtcgaataaa tggcagacca
     1501 accattctct ctcgtagtta caatttatac tcaacgattc aacgagcaga tgatattgtt
     1561 gtcattcttc cctccgaagc tggcgagaaa cattttgaat ccgacgaaaa agtcaaactc
     1621 atcaacccac atattaccgc agaaggttat aaaattggca atcgaggatt taccaattac
     1681 attatgcacg cagacgatat ggtgaaagca taagaaagga aaggtgaaaa aatatgagat
     1741 tagcagaagg tattgtgatt gaaaaagacc agacatttgg cacattgaaa ttttccgcct
     1801 tgcgtcgtga ggttcgtatc cagaatgaag atggtacggt ttccgaagaa attaaagaac
     1861 gtacctatga cttaaaatca aaaggacaag gacgcatgat acaagtcagt atccccgctt
     1921 ctgttccttt gaaagaattt gactacaacg cagaagtgga attaatcaat cctgtggcag
     1981 ataccgtagc gacggctact tttcgagggg cagacgttga ttggtacgtg aaagcagacg
     2041 atcttgtatt aaaaggacag acaaaacctc atcagaaata taaaaaagaa gcgtccgaaa
     2101 gtgaaaaata ggtgttgctt atgacaaaca caccattgat tttgaaagaa attccgaagg
     2161 atgaagccat ttcttttatt cggcaatacc attattcaaa gatactccct agattgtgta
     2221 aatactttct agggattttt tcagaagaaa aattattagg cgttgtggaa ttaggctggg
     2281 gtacgcaacc cctacaaacc atacgcaaac tctttcccga cagttccctt caaaccacag
     2341 attatttaga aattggaaag atgtgttttc ttccagaaat gaatcaaacc aattattttg
     2401 gcagtcaagc tctttcagct ctaattaagt ggttgaaaga acatacggac tgtcattttt
     2461 tatatacact ggcagatgga attgagggaa aatgtggcta tgtctatcaa gcgtccaact
     2521 tcttttactg cgggtatttc aagacaagtg tctatcgtga taagcagtca tgggaaaaga
     2581 tacaccctcg aagtgctcgc cttttattag aggaaaatgc tcgctttgaa caggtagaga
     2641 aaaagcattg gctttcccag gcattttgcg aatacaaagg gattgagaaa atcaatggac
     2701 gcatgtttcg ctatctctat ccgttgacaa aagaagcgaa aaaactgtta ggacacactc
     2761 tctatcgacg tcattattat ccgaaagaaa aaaatttacg ctttgaaaag cgaatcgctt
     2821 atcagaaata tgaagccatt tctcaaccaa cttttgataa acaggctcgt atctacaata
     2881 cacaattatt ttgataggtg gaaaggagga tttttatgcc attgcttcat gacagaggag
     2941 agcgaatcaa agccaacgat aagcacttgg tctatcattt tgtactaatt tcattgctgg
     3001 tagtttttct agtcgtccta ctcccttttc attggagagc gttacaatcg gtgaactggc
     3061 aagcagttca gttagataca tttttctatc aacttcatac gccatacttt tggagcagta
     3121 ttctcactgc tctttttgta tgcggactta tcagctggct ttattatcac tatcgtatag
     3181 attctataaa acagttagag caccgtcaaa agttagctcg tatgatttta gaaaatcatt
     3241 ggtatgaagc cgaagaaact caatcagagg gattctttaa agatttaccc agcaagaaaa
     3301 ccaaacaacg aatccgccat tttcctaaaa tatattatcg aatgaaagat ggactaatcc
     3361 atattcatgt agaaatcacc ttagggaaat atcaagatca gcttttgcac ctagaaaaca
     3421 aactagaaac aggattgtat tgtgaattag tggaaaaaac gttgaaagat tcttatgtag
     3481 agtatgtcct actttatgat actattggca atcgaattgg cattgaagac gtggtagctc
     3541 aagatggacg tgtcaaattg atggaatcgg tctattggga gttcgattct ctccctcaca
     3601 tgttaattgc tgggggcact ggtagtggaa aatcctattt tattctcaca ttgattgaat
     3661 ctctcctgca tacaaatgca aagctttata ttcttgaccc taaaaatgct gatttggcag
     3721 acttaggggc ggtcatgaat aatgtctatt accgtaaaga agatatgttg gcatgtatca
     3781 atcaatttta cgaagatatg attgatcgca gtgaaaccat gaaacaacac cctaactata
     3841 aaacaggaga aaattatgct tatcttggtt tgtctgccaa ttttcttatt tttgatgaat
     3901 atgtggcaat gatggatatg ctaggtcgtg aaagtaccac cgttattcat aaactcaaac
     3961 aaattgtaat gttaggacga caagcaggct tctttttaat tcttgcctgt caacgtccag
     4021 acgcaaaata ttttagtgat gggattcggg acaactttaa cttccgtgtg gctttgggtc
     4081 gtatgtctga aatgggcttt ggtatgatgt tcggaagcga tacacaaaaa caatttttct
     4141 taaaacccat caagggaaga ggttacgtgg atacaggaaa aagtgtgatt agtgagtttt
     4201 atacacccct tgtaccaaaa aggtacgatt tcttaggaga aataggaaaa gtcattcaaa
     4261 aaaagcaatc tgagcctgta ccgcacgaag tgaaaggtac aggttcagac ttgctttgat
     4321 tggtgtggcg ttagccacgc caatccttta gccccctcta tctaacaggg gggcacaaat
     4381 acaactgaaa acaggcaatt ctcatcaacc aatgttgatg gtacaaagga ttgcggaaaa
     4441 tatgaaaggt gtaaactcaa gggtcatagt ttacatcttt tttagattgg aggtttgcga
     4501 atggaaaacg aaaaaatttg gattaaggaa ttgaaagaaa agcgactggc ttatggcgtt
     4561 tctcaaaata aactggcggt tgcttctcat attaccagac cttacctatc ggatattgaa
     4621 acaggcaagg cagtccctac tcaacaggtg aaagaagatt tactgaacgc tttggaacgc
     4681 ttcaatcccg ataacccatt ggagatgtta ttcgactatg tacggattcg attccctacc
     4741 aatgatgtgg ctcaaattat cggtgaggtt ttacgtttga atatggatta tatgctacac
     4801 gaagactttg gctattattc ttatcccgaa cactatcgtt tcggtgatat tgttgtccta
     4861 gtctctcatg atgtaagtaa aggtgtttta ttagaactga aaggaaaagg ctgtcggcaa
     4921 tttgaaaact ttctattggc tcaacatcgg agctggtatg atttctttca agattgcatg
     4981 gaacataaag gtattttcaa acgcttggat ttagctatca acgataaaac agggattttg
     5041 aatattccag atttggcaaa gaaatgtaaa caggaagaat gcatttccgt ctttcgaagc
     5101 tttaaaaatt atcgcagtgg tgaattggtt caccgtgatg aaaaaccata catgggaaac
     5161 acactttata ttggctcatt aaaaagtgaa gtctatttct gtatatatga gaaagattat
     5221 gagcaatacg tgaaaaatga tgttccctta gaagacgcag aagtaaagaa tcggtttgaa
     5281 attcggttaa aaaatgaccg agccacccaa gccatgaaag atttattggc acatcaacag
     5341 gcggaaaaaa cagcctttga aattatcaat cgctatatcc gctttgcaga taaagacgac
     5401 actaaacgtc ggagtgattg gaaaactaat gaacgttggg aatggtttat cggtaaaaat
     5461 cgtggagcat tacgcctaac cacacagcca gagccttatt cttttgaacg aacattgaac
     5521 tggttacatc atcaagtcgc ccctacatta aaaatcgcaa gcattttaga tgttctcaac
     5581 ggtacaacca ttatctccac catgattcag gaagccaaac tgacagaaaa acatgagaaa
     5641 ttaattgaac aacaacatct agccatggag gatttgatta catgagcctt ttaacaaaag
     5701 aattaaagaa gttagggttt cagtgtggca ttgagtttca agcgtatata caaaatacag
     5761 ggaaatatac gtctctcatt attgagggaa aacggcaagc tggtgatacc atctatacct
     5821 atgattttta caaggtgaga ttttataata attataccaa tcgagtaacc gtctatggag
     5881 agcatttaac cccttttcaa ttattaaggc gtgtaaaaag ctatatctat tatcgagaaa
     5941 aatatcttaa ggaaaggagg acaatcacat gaattttggg cagaatttgt acaactggtt
     6001 cttggataat gcacagtcat tggtattgtt agcgattgtt gtcattggac tgtttttagg
     6061 ttttaaacga gaattttcaa aactcattgg cttcttgatt attgctctaa tcgccgtcgg
     6121 acttgtgttc aatgcagctg gcgtgaaaga tgtgttatta aacttattta accgaatcat
     6181 tggtgcttaa cagatatttt tcatgataaa ataggaagta tatattttgt tatgaaagga
     6241 tttatgaata tgtttacaaa tgatcaattt aaatctcttt taattaaaac attagaaaga
     6301 aagagctctt caaattatta tgaaggaggt aacgagattg tttctaaaat gaaaatatca
     6361 gaggtaactt tagatgagac tgacgatttt acttattata aaggatataa aaagggctgg
     6421 aatacgcttt gcacatatct taaaataaga gttccttttg atgatttaga cttttttgaa
     6481 agtcataaag atttgattac ccagacagca agctccatat atgataaaca aggtgataat
     6541 gtattagtgg atactatttt agtaccactt ccagagaatt acgaagtaat taactttagt
     6601 cagttgaaaa ttagtgatgt ggtttcacaa gctattgaag acgctgagtc ttttatgagt
     6661 aatggtgaat atcaacgtgc ctttgacaga gttcacactg cttttcatgg atatttaatt
     6721 gaaatactaa aaaaatatga aattacagtt cctagagacg aaaatctatc taaattatat
     6781 agtaggatac aacaattaat tgaaaaagaa attcaaccta ctgaacttgc tgatatagtg
     6841 aagacaacga taaggtcatc aaatggaatg attagctctc ttaatgaagc aagaaatagg
     6901 cattcacttg cacaccctaa tacaaatatt attggaaaga gagaagcaaa actaataata
     6961 ggtatttcaa gtacagttac agattatatt agcggatacc ttgataagta gcgtcattaa
     7021 ctgattgcta ctttttttat gactattttt ataaaaagga tgtgataaga attggaaatg
     7081 aaagtctatg tggcaaattt aggacggtat aatgaaggtg aattagtcgg agcatggttt
     7141 actccaccaa ttgatgagga agaaatggca gaaagaatcg gtttaaatga ggactacgaa
     7201 gaatatgcaa tacatgattt tgagcttcct tttgatgtgg acgaatacac gccgattagt
     7261 gaaatcaacc gtctatgtga agccattcaa gaaatcgaag gtacacctat ttataatgaa
     7321 ctcaaagaaa ttcaaggcat gtggtttagt agcttggaag aattactgga aaacaaagag
     7381 gatattcatt gttatagtga ttgtgattcg atggaagatg tcgcccgtta ttacgtggaa
     7441 gaaacaggac agcttggtga agtcccttcc aatttacaaa attatattga ctaccaatct
     7501 ttgggacgtg atatggaaat agagggtaat tacctagtta cctctcatgg ggtatttgaa
     7561 tattgtcagt aagtttaaca atccgtgtta taattaaatt aataaatagc acggagaggt
     7621 ataaattatg gtaaatgtat ttgaaaatct taaactatta aaactagaca tgaaagataa
     7681 aggctgggtg atagattcct tttactttcg ttacaaacag caaaattata ttgtacttgt
     7741 taagctattt gaaaaagagg aaaaagttcc agaatatgct ctgttaaaac tagaattttt
     7801 aaaggaaaac gatttttcag atatgctagc tgtctatgct aattcggtaa aattatatac
     7861 agacacgaaa acaataagag aatattttgg tatcgaatac agtagtaact tgggagatgt
     7921 tttatttcaa tttagccaaa ctcttgctcg atttattccg acagaagtta gtgagaagaa
     7981 aaatgaagac caaaaagaag ccatgtgttt ctcattaagt caaagtgatt cagaagatcc
     8041 cagaaaaaaa tattgttttt cagttagaag aaatccttta aagggaaatg gtgagctggg
     8101 aaaacgaagt ccttttaatg acaataaaac gagattgtat agacccagct tatatgaacg
     8161 attagggtca gataccaatt taagtttcag atattcaatg aatccagatg atgaagaaac
     8221 tgatgaaggt attattgcaa aatggacaaa aaataaaatt gaatagttaa agcattgaaa
     8281 gagcaatcac ctattttgat tgttcttttt ctatttttac ggaaaggacg tgaagacatg
     8341 aaaaaaataa gaagttacac cagtatttgg tcagtagaaa aagtgattta tgcgattaat
     8401 gatttacaac tccctttccc aattaccttt acgcaaatga catggtttat cgtttctttg
     8461 tttgtcgtca tactctttgg cagtttacca ccactttctc tgattgacgg agcactactc
     8521 aaatacttag ggattcccat tgttctcact gggttcatgt gccaaaagac ctttgacgga
     8581 aagaaaccct atggatttct aaagtctatc attacctatg ctctacgccc taaagtaacc
     8641 tacgctggca aacaaatacg attaaaaaaa gaaacaatga atgaatcgat tacgattgta
     8701 aggagtgaac aactagatgg catatccgat taaatatatg gaagataatc tcgtatttaa
     8761 tcatgatggc gaagtattcg cttattatga attaattccc tataattaca gttttttaag
     8821 ttccgatgaa aaaattcaag ttcatgataa tttctgtcaa ttgattgccc aaaatcgtga
     8881 tggcaagatt catgctctgc aactagcaac cgaatcaagt attcgagcca cacaggaaca
     8941 atcgaaaaaa gaaatcactg gacgattaaa agagatagct tacgaaaaaa tagatgaaca
     9001 gaccgaagcg ttaatttcta tgattggtga caatcaagta gactatcgct tttttattgg
     9061 ttttaaactc tacctcaatg aacaggaagt atccgtaaaa aatgttggga aagaaattca
     9121 aaaagcattt gcggaattct ttcatggtgt gaatcacaaa ttaatgggcg attttgtttc
     9181 tatgcctatg gcggaaatcg aacgcttttc taagatggaa cagttgttag aaagtaaatt
     9241 atccagacgc tttcagattc gtaaattgga gaaagatgat tttggttata ttattgaaca
     9301 tctttacggg caaacaggtg tcccttttga tgactacgac taccatttac cgaaacgata
     9361 cgaagataaa aaagtgttgg taaagaaata cgatattctc aaacccactc gctgtttaat
     9421 cgaagaaaat caacgctatt tacggattga acaggaagat accactactt atgtggcgta
     9481 ttttacaatt aatagtattg ttggtgaatt ggatttccct aatagtgaaa ttttttatta
     9541 ccagcaacag cagtttactt tccccgttga taccagtatg aatgttgaaa ttgtcgccaa
     9601 taaaaaagcc ttatctaccg ttcgcaataa aaagaaagaa ctgaaagatt tagatagcca
     9661 cgcatgggaa agcgacaacg aaaccagtac taatgtggtg gacgctttag aatctgtcga
     9721 tgaattagaa agtaatttag accaaaccaa agaatctatg tacaaactaa gctatgtggt
     9781 acgggtatca gcaaagaatt tggacgagct gaaacaacgt tgtgatgaag taaaagattt
     9841 ttatgatgat ctgtctatca aattagtacg accttttggc gatatgctag gcttgcataa
     9901 tgaatttatt ccctcaagca agcgatatat caatgactat attcaatatg tcacgtcgga
     9961 ttttttggct ggtcttggtt tcggtgctac acaaatgatt ggtgaaaatt ctggtattta
    10021 cgtcggttac aatctcgata caggcagaaa tatttatctc caacctagcc ttgcaagtca
    10081 aggaattaaa ggctctgtaa caaatgcatt agcgtccgct tttattggtt cattaggtgg
    10141 cggaaaatca ttctctaaca atatgctggt ctattattca gtactctttg gcggacaggc
    10201 aaccattgtt gacccaaaag ctgaacgtgg tgaatggaaa gaaaccttac ctgatattgc
    10261 ccatgaaatc aatattgtta atctcacgag tgagaacgac aataaagggt tacttgaccc
    10321 ttatgtgatt ttaaaactcc cgaaagattc agaaagcctt gccattgata ttctcacgtt
    10381 cttaacaggt atttccagcc gagatagcga gaagtttcct gtcctgcgta aagctattcg
    10441 gagtgtaact caaagcaaac aacgagggtt gttattggtg attgatgaat tgcgaaaaga
    10501 agatacgccc atcagcaata gtattgctga ccatatcgaa agctttgtcg attatgattt
    10561 tgcccatctg ttattcagtg atggcagtgt cacccaatcc attagcttgg aaaaacaact
    10621 caatattatt caagtggcag atttggtctt acccgattcc aatagctctt ttgaagaata
    10681 cactaccatg gaattattaa gtgtggcaat gctgattgtc attagtacct ttgctttaga
    10741 ctttatccac tctgaccgtt ccatttttaa aattgttgac cttgatgagg cttggagttt
    10801 tttacaagtg gcacaaggaa aagctctatc tatgcgattg gttcgagcag gacgtgccat
    10861 gaatgcaggg gtctatttcg ttactcaaaa cgcggacgat ttactagatg aaaagatgaa
    10921 gaataatatt ggcttgaaat ttgcctttcg ttccactgac ctagtggaaa tcaaaaagac
    10981 cttagaattt tttggtgtgg acaaggaaga tgaaaacaat cagaaacgct tacgtgaatt
    11041 agaaaatgga caatgtttag tttcagacat ctatggtcgt gtaggggtta tgcagtttca
    11101 cccgattttt gaagagttgc ttcatgcctt tgataccaga ccgcctgtgc gaaatgaggt
    11161 ggaagaatga cacaaaaaca aaagaaattt cttcactata gttggataac gctcctttgt
    11221 gtgggcgtta ttttactttt attaggcacg ctgggcaatg cagtacaagc gacaggctta
    11281 gttgatgaaa ccattgatac aagcaatgaa tactccaagt atggtttgaa tcaatatcag
    11341 cttgattatt atgtggacaa tagctggggc tggcttccat ggaattggag tgatggcata
    11401 ggacaatcgg tgatgtatgg attgtatgcc attactaatt ttatttggac aatttctctt
    11461 tatctatcga acgccacagg ttatttggtg aaagaagcct atgccttaga tttcattagt
    11521 caaacatccc aagcaattgg cgaaaacatg cagacgattg caggcattac accgaatggc
    11581 ttttccagtt cagggtttta tgtcggtttc ctccttcttt ttattctcat tgttggaatc
    11641 tatgttgcct atacaggatt ggttaagcga gaaacgacga aagtgatacg agctgtttta
    11701 aactttgtcg tggtgtttat tctatcggct tcctttattg cgtatgcacc cgattatatt
    11761 gcgaaaatca atgatttttc caaagatgtc agtaccgcca gtctgaatat tgggacaaaa
    11821 attgttcttc ctaacacgga tagtcaaggg aaagacagtg tggacatgat acgtgacagc
    11881 ttattctctg ttcaagtaaa gcaaccatgg ctattgcttc aatatggctc cactgatgta
    11941 gaagcgttag gggaagaacg tgtggaaagt ttattgtcta ccagtccaga tacaaacaat
    12001 ggtgaagata gagaaaatgt agtgattgaa gaaattgaag atcatgacaa tacctattta
    12061 accctaccga agacgatttc cagattagga acagtcttct ttttgtttgt attcaatatt
    12121 ggtatctcga tttttgtttt ccttctaaca ggaatcatga ttttttcgca agtgctattt
    12181 attattttcg ctatgttttt gccaatcagt ttcctattaa gtatgttgcc gagttttgat
    12241 ggcatgggca ggcatgccat taccaagtta tttaatgtga ttatgacaag ggctggtatt
    12301 accttgatta ttaccgttgc ctttagtatt tccactatgc tttattcgct gtcagcaagt
    12361 tctccctttt tcatgattat gtttttacaa attgtgacct ttgcagggat ttattttaaa
    12421 ctgggcgatt taatgagcct attcacttta caaagcaacg actctcaaaa catgggcaga
    12481 caagtgtttc gcagacctcg tcaaatgatg aatcgacaaa ccagaagatt tcaacgcagt
    12541 atgagtaaga tttttcgtgg aaaagcaggg tcaacgaagc aaaagacaat gacaacaaag
    12601 cagaatcaaa ccaataaagc taaccatact cgtcaaaatg aacggactac accaaagaaa
    12661 gaaacagcac tttccaatgt gaaaaagcaa caaggcggta tcgggcaacg attaggtgaa
    12721 aagacagccc atgtattgga cacgaaaaat cgtctagtca ataaaagaaa gcaggcaaaa
    12781 caacagatac aggcgacacc aacccatgtc aaatatgccc ttcatcaagg aaaagagaat
    12841 gtcactcata atgtaacaga ctttaaacaa tctatggcag ataccaaagc tcaacgcaaa
    12901 caacagcgta tgaaccagca ggagcaaaaa cgaaagaaca ttgctcaaaa gcgtttggag
    12961 ctggataaag caaaagaaaa aagacgaaaa gaaaacccat catctcctgt tcagaataac
    13021 cagcagcatg ttcgcaagcg tcagcaaacc gtcacgcctg ttttgtcaca aaacactaaa
    13081 cgtgaaaatc atcagcgacc attgaaaaaa gagcaaaaac aaaagacacc accgaagcaa
    13141 ttcaatcaga ggaagctaaa taaaagaacg gataagcgag gacaacaaac atgaagctaa
    13201 aaataacagt gatttgtagt gtggtcttct ctctcttctt ttttctctta ttattcctag
    13261 tcattttctt tgcagatgat acggacagtg gcgaaaacaa caaggattct tctattccac
    13321 aaggcggtgt gaccgtttca ccagaagtgt tggcacaccg tccgttgatt gaaaaatatg
    13381 gtaaggaata tgggattgaa gactatgttt cttatatctt agccattatg caagtggaat
    13441 cgggcggtac agcagaagat gttatgcaaa gttccgaatc tttgggttta ccgcccaaca
    13501 gtttgagtac cgaagagtcc atcaaacaag gggttaaata tttcagtgaa ttattaacca
    13561 gtgcagaaca acaaggagtg gatatagatt ctgttatcca atcttataat tatggcggtg
    13621 gctttttaaa ttatgtgagg agtcatggga aaaaatatac ctatgaatta gccgaacagt
    13681 tttctaaaga gaagtcgggt ggtcaaaaag cagactatcc caatcctata gccatacctg
    13741 tgaatggtgg ttggcgatat aactatggaa atcagtttta tgttcagttg gtttcacaat
    13801 acctaaccga cacttcccca acagaatttg atgatgaaac cgtgcaagtc attatggacg
    13861 aagccttgaa atacgaaggg tttccctatg tctttggagg ggcgtcgcct accacctctt
    13921 ttgattgtag tggcttaata caatgggtgt atgacaaagc tggcatttct ctccctcgtg
    13981 tcgcccaaga tcagtatgac gctacgcaag aaatctctat ggaagaagcc caagcaggcg
    14041 accttatctt ctttcattca acctataatg caggcacata tgtgactcat gtggcgatat
    14101 atttagaggg aaatcgcttt tatcatgcag gcgacccaat cggttatggc gacttaagca
    14161 gtcgttattg gcaagaccat ctgattgggg ctagacgtgt tattcataac taagaaagga
    14221 atgaatcaaa tgattataaa aatcgagcga aaagaaaaga aggagaaacc aaagaaatct
    14281 aaaaaaccga gcaagcaaag aaaagttccg atgattaaag ttggcacgca taagaaatta
    14341 acctttgttt tatgggtttt attgattggt agtgtcggat ttggaatcta taaaaatttt
    14401 actgccattg acactcatac tgtccgtgaa acagaaatca ttaaacagca gattgtcgat
    14461 accaaccaag tagaaagttt tgtgaaatcc tttgcgaaag actacttttc gtggcaacaa
    14521 tcccaagaag ccattgataa acgaaatgaa aaattgaccc attatttgac ggaagaattg
    14581 caggtattaa atgaagaaat gattcgtaag gatattccta ctagttctag tgtgaacgat
    14641 atacaggtgt ggcaggtttc tcaagtgaat gagaacacct ttgaggtact gttttctgtt
    14701 gaacaagtta ttaccgaaga caaagacaag gaaactatat cgtctagctt tcatgtggtt
    14761 gtccatatag atgaatcaga taatatggtt attatcaaaa atccgacaat gagtaagaaa
    14821 cctcaaaaat cggactacca acccaaacag ctagaaagtg accatacagt agatacagaa
    14881 acgatggacg aaatcactag ctttttagaa acgttcttcc agctctatcc taccgccaca
    14941 gaaaaagaat tgacttacta tgtaagtaat catgtgttac ctatgattaa caaggaatat
    15001 gttttcgagg aattggtgaa tcctatcttt accagaaaag ataaccaagt aatcgtgaat
    15061 gtcgctgtga aatatttaga tcaagaaaca aaggcaaccc aaatctcgca atttgagttg
    15121 atattagaaa aacaagataa ttggaagatt gtaaaataac aaatattggt acatgattac
    15181 agatactttg taatcatgta ctctttttga taaaaaattg gagattcctt tacaaatatg
    15241 ctcttacgtg ctattattta agtgactatt taaaaggagt taataaatat gcggcaaggt
    15301 attcttaaat aaactgtcaa tttgatagcg ggaacaaata attagatgtc cttttttagg
    15361 agggcttagt tttttgtacc cagtttaaga atacctttat catgtgattc taaagtatcc
    15421 agagaatatc tgtatgcttt gtatacctat ggttatgcat aaaaatccca gtgataaaag
//
LOCUS       DAIGTA010000062        15255 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.065, whole genome shotgun sequence.
ACCESSION   DAIGTA010000062 DAIGTA010000000
VERSION     DAIGTA010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.065"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..1235)
                     /locus_tag="NOB43_002207"
     CDS             complement(<1..1235)
                     /locus_tag="NOB43_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCI0983048.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQK"
     gene            complement(1228..2820)
                     /locus_tag="NOB43_002208"
     CDS             complement(1228..2820)
                     /locus_tag="NOB43_002208"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCI0983049.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(3330..4055)
                     /locus_tag="NOB43_002209"
     CDS             complement(3330..4055)
                     /locus_tag="NOB43_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983050.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(4209..4535)
                     /locus_tag="NOB43_002210"
     CDS             complement(4209..4535)
                     /locus_tag="NOB43_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983051.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(4572..4937)
                     /locus_tag="NOB43_002211"
     CDS             complement(4572..4937)
                     /locus_tag="NOB43_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCI0983052.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(4974..5189)
                     /locus_tag="NOB43_002212"
     CDS             complement(4974..5189)
                     /locus_tag="NOB43_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983053.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            5318..5653
                     /locus_tag="NOB43_002213"
     CDS             5318..5653
                     /locus_tag="NOB43_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983054.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(5729..7726)
                     /locus_tag="NOB43_002214"
     CDS             complement(5729..7726)
                     /locus_tag="NOB43_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983055.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(7824..8099)
                     /locus_tag="NOB43_002215"
     CDS             complement(7824..8099)
                     /locus_tag="NOB43_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983056.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            8331..9065
                     /locus_tag="NOB43_002216"
     CDS             8331..9065
                     /locus_tag="NOB43_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983057.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            9104..10246
                     /locus_tag="NOB43_002217"
     CDS             9104..10246
                     /locus_tag="NOB43_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0983058.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(10580..11491)
                     /locus_tag="NOB43_002218"
     CDS             complement(10580..11491)
                     /locus_tag="NOB43_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983059.1"
                     /translation="MGERTFEDVKDYVELQSQEKCTVLSAKPEQEFNDLGTEVTVWNV
                     KTDTDGDWWVVEGDNVPMNLYPQSAYYFGTDEVYSFHMGLMERMRVLHEKYDPEDFVR
                     SVTLDTEIAPQLFRKLKNVATLIDSAEEIEDFQSIGVQCREILIELGNHIFIADMAGT
                     KEQPQKSNFKKKAELFIQFYLTGSDNSDYRSIIKKLTESTWDYANKLTHSSTTTKYEA
                     STCVMLVTSLVGVYENITQKVFDPVSQYICSSCKSKKLTIDSDDSDENGMVESLYLKC
                     EECGDITKVVFLTSDKDSSYTKGKIIE"
     gene            complement(11596..13026)
                     /locus_tag="NOB43_002219"
     CDS             complement(11596..13026)
                     /locus_tag="NOB43_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983060.1"
                     /translation="MDDIKEVFLEVLSRYIQDNLLEYQNNGKKYEFSFDIKNYNDSLH
                     VVFQYNKAGKIGITDVHSFQIFLNEINIEASKSHLNYTTILDTNSLFFSKKLLPYLHS
                     YEWALRKLIYLLAPTYFDNWTKDSIPDEMISAVKGKQKQAIGKYDLENLLQWIDLYDF
                     EEYLFGENYLFISTGNEKNIVRYKEIIVEELLNLFRETDDLSLSDPFSLWSEVFSKYM
                     YVDLEEIRKDMELIREGRNIVSHNKEIKYSLYKDLIKNLKKYVKQLNEAFKKILIGEI
                     ADEKLFDMTNDFEAYIGNHYSNINLPNATKLLTSLSAMTVLNTDSTKKMMETIGPALS
                     VQRAVMQNIDTEGFRRATEGMKQSLSAMTVLNADSTKKMMETISSALSAQRAVMQNID
                     TEGFRRATEGMKQSLSAMTVLNTDSTKKMMETIGPALSAQRAVMQNIDTEEFRRATER
                     MKQSLSPKQALKSDYKIADDIEDSNK"
     gene            complement(13195..14124)
                     /locus_tag="NOB43_002220"
     CDS             complement(13195..14124)
                     /locus_tag="NOB43_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983061.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHVRNYSQHGHLPVNIE
                     QQRVYFDLDEILTMPHFDLNEKLKSEIDEIKEDISARFEDFPRISYVYTIAKFNLITT
                     EIYLNYLKEVKPILMEMDKEKNELLLNTKFKLTNSDGKSSDVVFYDFDGENYHCFNRT
                     DNSLSMYASIKKEVKKILREEEQYYKEIKNKNQ"
     gene            complement(14372..14722)
                     /locus_tag="NOB43_002221"
     CDS             complement(14372..14722)
                     /locus_tag="NOB43_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983062.1"
                     /translation="MIFENESEEIGRVAEENKVDPLETLVINKKEFEQLFLDFFIQYD
                     MIYDFSSSLDLFELEAEIIENSREKNGKIIISVEKFNELFSETFEIDPDYYQPQEVFR
                     EFRNQIIRSSNIEN"
     gene            complement(14937..15255)
                     /locus_tag="NOB43_002222"
                     /pseudo
     CDS             complement(14937..15255)
                     /locus_tag="NOB43_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348881.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4841 a         2850 c         2142 g         5422 t
ORIGIN      
        1 atcttttgta agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga
       61 gcgatcgtgt cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc
      121 ctagtaaaag gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt
      181 ccttcagtgt tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg
      241 aactcattat ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc
      301 gtcataccaa gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg
      361 aattcatttg gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca
      421 tcaaactgtt ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag
      481 tctaaatctt tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt
      541 tcccaatctt ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg
      601 aacatttttt gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga
      661 agagcgatag tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat
      721 attggaaatt gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct
      781 gaacctggat tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata
      841 aaatattctg aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat
      901 acacccggtt ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc
      961 atgataaaat cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta
     1021 attttatatc ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa
     1081 ttgctattag atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact
     1141 ccatcttttt tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct
     1201 gggaaacgaa tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg
     1261 taaccacgct tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt
     1321 ttctagcact tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc
     1381 aattggttct tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt
     1441 ttctttgatt tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc
     1501 ataggtttcg aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt
     1561 gacaaattct cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa
     1621 tacaatcacc gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac
     1681 agcataaata ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg
     1741 gaataaaact ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa
     1801 accatgaaga agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt
     1861 aaaccgagaa tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt
     1921 cattactact gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc
     1981 cccattgcgg agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc
     2041 tagattgtat gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt
     2101 taagtagtta cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact
     2161 aaagaatcgt cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat
     2221 atgaggcgtg taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag
     2281 aaattcataa gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa
     2341 tttcttaatg acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt
     2401 tgattggaga tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg
     2461 cacaaaggct ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa
     2521 gacgttgaaa agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat
     2581 cagatcttct tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct
     2641 taccgtatca tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg
     2701 gtcggataaa tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc
     2761 cattttgcta cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa
     2821 aaagatacac tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc
     2881 ccttttagaa aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga
     2941 aaggagtcta acgttgtttg atataactta gactgatcgt taacttattt tttatatttc
     3001 tacatagtta tctttagaac catttcagat acatatgaaa caattacata tgattttttc
     3061 ataaaaaaac agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac
     3121 taaaatcact acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct
     3181 ccgtttcatt tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc
     3241 cagtagctta tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg
     3301 gtaaataaat gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg
     3361 taatcagtta cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt
     3421 aaccgaagtg gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga
     3481 ttagctaata aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc
     3541 gtgattcctt tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct
     3601 acaaatgaat taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct
     3661 gtatatatgg cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca
     3721 ttagttagta aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc
     3781 ctaacagctt taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct
     3841 tccataaacc ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct
     3901 ttcatttctg agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc
     3961 tgattcgttt ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt
     4021 gccaaacaaa tccataataa ttttttcttt ttcatttttc ctcctataca ctgctgttat
     4081 aacagtgact aatgtaaaga ttttcccagc aatcatcaga ctattattta cagggaatca
     4141 aaaaaactcc ttagtaagct tacaccttta ggagttcctg tttgaacggt atgcataata
     4201 catttaaatc aatttaacat taacacctca gtatatggta tctctacata tacacggtct
     4261 ttttttggat agtactcgac atttatattg atagcacttc cattgtctaa cgtagcttta
     4321 gcccggtacg tgttatcacc attatcatga gtgatcgtca catcatcaca tgtccgattt
     4381 aagttatact gttcttgtaa aatctgagtt accaatggta cagatgactt ctctagtcca
     4441 gatgaacccg tcattcttga aaaaattata cctataatag ccaatacaac gatacctata
     4501 atgacaaact tcttattcat atttacttta ttcaactttt tatctcctat ctccaaaatg
     4561 attttctctc atcagtaact cattgacatc cccaatagta caccaaagat ggctccagct
     4621 acccctgcta tcatcaaaat cgtacccatt tgttcatctt tctctcgata taagtaaccc
     4681 ataataacag caacagcacc aaataccaca ggaataaatg ctaatgatac taccatagaa
     4741 atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc
     4801 atttcattaa ttgtctgctc agtacttttc tttactgtgt ctgttccggt tgtctcatct
     4861 gtttcttgta atgctccgca aaactggcaa tacttacttt catttgttat ttctttacca
     4921 cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttat tagctaactg
     4981 tttactttat taaatacatc agaaaacagc tcatttattg gtacacttaa tatctcagaa
     5041 agcattttca tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat
     5101 tgctgtgtaa cattcatttt tttggctaac tcagtttggg aaagtccttt ttcttttctg
     5161 tatcggctga gattacttac ttttttcatg attctcccct cctgttttat tatatacaac
     5221 aatatgatgt atttcaactc ataaaatata taaatacttc aaatgtcatt acaaatacaa
     5281 caacttgttg tactctactg agaagggggg tgtattaatg aaacagaagc aatatgcaaa
     5341 ggtcattaga gaaaagcgaa aagcactcgg gtggacacaa aaagaattag ctaaaaaaat
     5401 cttctctaca caacaggcag tagcaagatg ggaaaattct gtaacagaac ctaacctcga
     5461 tagcttaaca gctctttcta gagccctagg aacccctgta agccattttc tagacaatgt
     5521 tgacatagat tatgaggaag agtttttggc tctctatcgc tctcttagta ctgaagatgc
     5581 aattcgaaca attgactata tgaagctatt aaaaaggcaa gaaaatgaac gcaatcagct
     5641 attgaaagat tgaaaaataa ataacccacc gaactttaac ggtgggtgta ttgagatgaa
     5701 ataagattaa gagctatgga taacctgtct agtttaatat aattgggtct cttctattcc
     5761 ttactctccg tccatcatct cttgttacac ttgtaaattg ataaatagga actaattcaa
     5821 ctcctgataa tatcaattct tttattactt catctatccc tgcccctttc gctagatata
     5881 ctaaaaaact actgcttgct ttcacattgt atagtttctt aatatcctta gaagctcgtt
     5941 caagagtgaa tccttgttta acaaagtagc ctctgttttc tattaaagca tttttcacgc
     6001 tgttatccct gacatttcgt aggcgttcac aaacagtgtt aataagttct ttttctgtca
     6061 ttagatatgt cccttgccac gataagccct gtaaaacttc atgtgcttca tctaaaatca
     6121 attgtttttc cttgctaagt tctgatcggg aattttgagg aaatactctt ttagcctctt
     6181 tttcgttaaa acatatctta acccattcat aagaaaaata ttgatatgta aaatgaaatt
     6241 tttccagaag tggaaggata tcttcattca atttttgaat cacagaagtt gcattaaaaa
     6301 cgtctaatcg atagacattg cttctcttat gtttaaagtt tcctaacgct ttctcttcct
     6361 ttaacctatt taggtattcg agcatcttca aaggaacatc ttcatcatct aattttttta
     6421 tcaatcctat aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt
     6481 taccatagta agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac
     6541 tttccttact atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca
     6601 tttcctctag ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt
     6661 caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt
     6721 tctctaatag ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa
     6781 ctccaataaa attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc
     6841 cagttttact ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta
     6901 agtttttact tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct
     6961 cattaaaaga catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt
     7021 ctttgtcgtc attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc
     7081 tccctgaatc actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag
     7141 taatatctaa catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa
     7201 aaaacattct attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt
     7261 attcgtaaac agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa
     7321 tcttgtattt ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat
     7381 tatgaactaa attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac
     7441 tcaaatctac taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta
     7501 ctctggtttc cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa
     7561 atgattgtga tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat
     7621 ctaaacacct atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt
     7681 tttctttatc tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct
     7741 tataaaattc tgttaaagac taaaacatac agataataaa aacaaactct ttattactat
     7801 atgttttagt cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca
     7861 gattttttaa atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca
     7921 tattttctaa tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata
     7981 tactctagag tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc
     8041 tctttcactt gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata
     8101 tttccccctc ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt
     8161 tctcaaaata aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt
     8221 catcgacata cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat
     8281 ttacaacacc ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac
     8341 gtccaccaat aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa
     8401 gaaagagtaa aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa
     8461 ttgacaaaaa gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat
     8521 tatcccgaat tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag
     8581 aagaatatat tttgggaatt attctttata gagatagcat tgtactagat ggtataacat
     8641 ttccagataa aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt
     8701 tagatacatg gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta
     8761 acaagacttg taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag
     8821 aagaattatt catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta
     8881 gcagtataga agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag
     8941 acatgtctta tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac
     9001 aaacgatttc atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca
     9061 tctagtggta agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa
     9121 gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc
     9181 acgaactggt gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca
     9241 aaaagattat gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga
     9301 tatgacattt gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc
     9361 ttcaacaatc gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa
     9421 gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag
     9481 taaatatgaa agttacgatt atatgagaaa acagactgca caaattttac gctacggggt
     9541 tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga
     9601 gtatgagaaa aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt
     9661 taaagatttt ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat
     9721 gagaaagagt gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact
     9781 acatgtcaat aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa
     9841 aacaagagct tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa
     9901 ctggaaatta cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga
     9961 gcaacatgtt tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg
    10021 gttaagatat attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca
    10081 tacacatgct agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt
    10141 agggcatgaa aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc
    10201 taagaaaaca ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa
    10261 atctggtcat ttctagtata caggcaaaac aaaaaagcta gaacccttat atatcaaggg
    10321 ttctagctcc tataacaggt ttacccaaca ctgccttcca atgactcttt tcaatagcat
    10381 tggtacatga ttcgcgttat aaaagcattt ttcccgctct ggtatatatc actgacagcc
    10441 tatcacagca cttgatatcc cccagaacgt atccaatatc gtacccaaaa aagcaggtag
    10501 agaagttatt tgaggtatca aatttaaaaa cgtgtgcact ttgaattgcg tgatatgttt
    10561 ttgacatgat ccataatcat tactcaatta tttttccttt tgtgtatgaa ctatccttat
    10621 cactagtcaa aaatactact tttgtaatat caccacattc ttcacatttt aaatacaagg
    10681 attcaaccat tccgttttca tcagaatcat cagaatctat cgtgagtttt ttacttttac
    10741 acgacgaaca tatatactgt gagacaggat caaagacttt ttgcgttatg ttttcataca
    10801 caccaaccaa agacgttaca agcattacgc aagttgaggc ttcatactta gtagttgtac
    10861 tagaatgagt taatttatta gcgtagtccc atgttgattc agttagtttt tttataatac
    10921 ttcgatagtc agagttatcg gaacctgtca aataaaactg tataaaaagt tccgcctttt
    10981 ttttgaagtt tgatttttgt ggttgttctt tagtacctgc catatctgct ataaagatgt
    11041 gattaccaag ttcgattaga atttctctac actgaacacc aatagattga aaatcttcaa
    11101 tttcttctgc actgtctata agagtagcaa cattctttag cttccgaaag agttgtggtg
    11161 caatctctgt atcaagagta acgctcctta caaagtcctc tggatcatat ttttcatgta
    11221 aaactctcat tctctccatt aaacccatat gaaacgaata tacctcgtct gttccaaaat
    11281 agtatgcact ttgcggataa aggttcatag gaacgttatc accctcaaca acccaccaat
    11341 cgccgtcagt atccgttttg acattccaaa ccgttacttc tgtaccaaga tcattaaatt
    11401 cctgttccgg cttggcactt aacaccgtac acttttcttg gctctgcaat tctacatagt
    11461 ctttaacatc ttcaaaagtt cgttcaccca ttatttacct ccatgatttt taccaaatag
    11521 attgtatttt tctagtttta tttcacctct ctaattcttt taatagttta ttaattggaa
    11581 aaagttctgg actctttatt tattactatc ttcaatatca tcagcaattt tataatcgga
    11641 tttcaatgct tgctttggtg atagagactg cttcattctc tcagttgctc gtctgaactc
    11701 ctcagtatca atgttttgca tgactgctcg ttgagcggat aatgccggac cgattgtctc
    11761 catcattttt ttagtagaat cagtatttaa tactgtcatc gctgatagag actgcttcat
    11821 tccctcagtc gctcgtctga acccctcagt atcaatgttt tgcatgactg ctcgttgagc
    11881 ggataatgcc gaactgattg tctccatcat tttttttgtg gaatcagcat ttaatactgt
    11941 catcgctgat agagactgct tcattccctc agtcgctcgt ctgaacccct cagtatcaat
    12001 gttttgcatg actgctcgtt gaacggataa tgccggaccg attgtctcca tcattttttt
    12061 agtggaatcg gtatttaata ctgtcatcgc tgataaagac gtcaataatt tagtagcgtt
    12121 gggtaggttt atattactat aatgattccc tatatatgct tcgaaatcat ttgtcatatc
    12181 gaaaagtttt tcatctgcta tttcaccaat tagtattttc ttaaatgctt cattaagttg
    12241 tttcacgtat ttctttagat tctttatcag atccttatat aaagagtatt taatctcttt
    12301 attatgactc acaatattcc ttccttctct gatcaattcc atgtcttttc gaatttcttc
    12361 taaatcaaca tacatatact tgctaaatac ttcactccat aatgaaaaag gatcagatag
    12421 acttaaatca tcagtttctc gaaataaatt taacaattct tctacgatta tctctttgta
    12481 ccttacaata tttttctcat ttccagttga aataaatagg taattttctc caaataggta
    12541 ttcttcaaaa tcgtataaat ctatccactg taaaagattt tctaagtcat acttgccgat
    12601 tgcttgtttt tgttttcctt ttactgcaga aatcatttcg tctggaatag aatctttcgt
    12661 ccagttgtcg aaatatgttg gagccaataa atatatcaat tttcttaaag cccattcata
    12721 actatgcaaa tatggtagta atttttttga aaaaaataat gagtttgtat ctaaaatagt
    12781 agtgtaattt aaatgtgact tgctcgcttc aatattaatt tcatttagaa aaatttgaaa
    12841 tgaatgtaca tcggttatcc ctattttacc agccttatta tactgaaata ctacatgtaa
    12901 cgaatcatta taatttttaa tatcaaaact aaattcgtat ttttttccgt tattttgata
    12961 ttctaaaagg ttgtcttgta tatatcgtga taatacttcc aaaaaaactt ctttaatatc
    13021 atccattttg ccttgtttag ggtaatataa atattcaaca acttgcttgc taatatgtcc
    13081 tcgccttctt ttctttcaac gatttaaaat tttccaaata acttgataac tactaagtaa
    13141 gcctcaaaca acaaccacaa atgaattttt cactaatatt gatgattgtg atatttactg
    13201 gtttttattt tttatttctt tataatattg ttcttcttct cttaatatct ttttaacctc
    13261 cttttttatg ctagcataca tcgataaact attgtctgtt cgattgaaac aatgataatt
    13321 ctctccatca aagtcataaa aaaccacatc acttgatttt ccatctgaat tagttaactt
    13381 aaatttagta ttgagtagca attcattttt ttctttatcc atttccatca aaattggttt
    13441 aacttctttt aaatagttca aatatatttc agttgtaatc agattaaact ttgcaattgt
    13501 gtacacatat gagatacgtg gaaaatcctc aaatcgagca gatatatctt ctttaatttc
    13561 atctatttct gattttaatt tttcattaag atcaaaatga ggcattgtta gaatttcatc
    13621 caaatcaaag tatactcttt gttgttcaat atttaccggt aagtgaccat gctgagaata
    13681 atttctaaca tgtaataaaa atctgtacga gaaatgttca tcataaggct tactcagaat
    13741 tttattctta aaagatttaa aatctttttc tgctaaaaag tttttcatac aaacttcaat
    13801 ggattcagtc aaagttttgg ctgaactaat taagtttatc gtcaaagcat ttatctgata
    13861 ataatactgg tcttccgtta atttttcacc tgtactttca attaaatcat tagtaaaaat
    13921 tgtgaagtgt ttgagcaaat tagttaaatt atatctaaac acattaaaaa gtttatccaa
    13981 ctctataata tgacgtgtta attctacata atttaaaaat attcttttat cagattctgt
    14041 tattgtttct aataatgaat caatctgcct tattagctcg tcatcttgta aattactgac
    14101 gaaaaaccta ctatcacttc tcataattat attctcctaa tatgattttt tcaaaataat
    14161 caatatgtaa catagaagta tactctattg ttacatacct tatttcttat tatatcagta
    14221 tttctctgtg acacataagg gtgtaacata attattttaa acgaaatgac tacaagtagt
    14281 cattgaagca aatctccata agacatttgt aaaatctttt aaaaagaagc gtcgaaagaa
    14341 ggaacttttc ttcaacgctt cttttattga ctcaattttc aatattactt gaacgaataa
    14401 tctgatttct aaactctcga aaaacttctt gtggttgata atagtctgga tctatttcaa
    14461 atgtttctga gaataattca ttgaattttt ctactgaaat aatgatttta ccattcttct
    14521 ctcgactgtt ttctattatt tctgcttcta attcaaataa atctagtgac gaactaaaat
    14581 cataaatcat gtcatattga ataaaaaaat caagaaaaag ttgctcaaac tctttcttat
    14641 ttattactag tgtttcaagc ggatcaactt tattttcttc agccactctt ccaatttcct
    14701 cactttcatt ttcaaaaatc acaaaaatga tattaactta aaagccacta acaaaataag
    14761 acttacaaag taaagggtaa tccaacaaaa taaccattcg ctctacgtac tacgatttgg
    14821 tagtcctgcc tttcaatcgg taattcataa tagtaattta ctgtttcttc tttgccactt
    14881 tcaatatact ctggattatc caatatcata gcatactcat aaagttcttc accatccttg
    14941 ttttcaatcg accattgttg tggacgtatc ggattttctg tatcatttat aagtgtatag
    15001 gtcacttgta atacacgatc atgttgtgca aattcatttc ttttttcggt cacttcaata
    15061 tttttaaatg ttagttcaac cccatctgcc tgataagttt cacctatttt taaatctttt
    15121 gttacaattt ttattggctt ttcttctgga aaatgtctgg ctttaattgt tagataactt
    15181 ccaaaaagaa tcaatcctag tagcactaaa agaattcctt taacgagcca ctgaaacggg
    15241 aagtaaactt taaac
//
LOCUS       DAIGTA010000063        14171 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.066, whole genome shotgun sequence.
ACCESSION   DAIGTA010000063 DAIGTA010000000
VERSION     DAIGTA010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14171
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.066"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..134
                     /locus_tag="NOB43_002223"
     CDS             <1..134
                     /locus_tag="NOB43_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0983063.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(145..555)
                     /locus_tag="NOB43_002224"
                     /pseudo
     CDS             complement(145..555)
                     /locus_tag="NOB43_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            complement(658..1953)
                     /locus_tag="NOB43_002225"
     CDS             complement(658..1953)
                     /locus_tag="NOB43_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0983064.1"
                     /translation="MNDSIKKMLRLIDKNLMITGVSYETFQKEKTLIVDAILSPAPCA
                     CSNCGSTVVDGTGKTIVVKNGKKETIVRFEQYNHMPMVMRLKKQRYTCKNCRTHWTAQ
                     SYFVRPRHSIANHVRYKITSLLTEKVSLSFIAKSCQVSLTTVIRILKEFKSYLPKSSK
                     RILPKVLMVDEFRSHASIEDKMSFICADGETGKLIDILPTRKLPRLTSYFLSCTNPEE
                     VEFLITDMNAAYFQLTKRVLPNAKVVIDRFHIVKHINQAFNDLRIREMNELRKAGKKR
                     QAEKLKKNWRFLLKKRSNINHYEYKTWKSFRAPKYPFFTEAMMIDRLLGFSTPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLEELPETLDDAFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIKVK"
     gene            2134..2444
                     /locus_tag="NOB43_002226"
                     /pseudo
     CDS             2134..2444
                     /locus_tag="NOB43_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009559264.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
     gene            2952..4244
                     /locus_tag="NOB43_002227"
     CDS             2952..4244
                     /locus_tag="NOB43_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCI0983065.1"
                     /translation="MDGITIPWYAAIIGLIFAVFLILKKMNPVYSLFLGAIIGCLIGG
                     ASLSNTVDILVTGTQSIMGTAIRVLAAGMLAGVMMESGAAESIAHAIVNKLGSNKAIF
                     SLALSTMIITAVGVFIPVAVLIVAPIALSVGKQTGISKLALLTALSGGGKAGNIISPN
                     PNTIAAANGFKLDLSNVMIAGFIPAIFGLATAVLIASLIKKKGGKVKDSDIQEKSEKE
                     LLPLRKALIAPVLSIVLLLINPIGTMLHIQVLADLKIDAMYILPFASIVGTIAMGQAS
                     QIREYSKSGIYRVTDTVLILIGAGAIAGLISVSDLSKQVVHLISITGISGTLLAPISG
                     ILMGLAVGSTSTAVILATGSFGHAILETGTNSLAAAVMVHTGATVIDSVPQGNYFHIT
                     ANSMNMSIKERMKVIPYEICVGGVMTIVATILYGFILK"
     gene            4379..5524
                     /locus_tag="NOB43_002228"
     CDS             4379..5524
                     /locus_tag="NOB43_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0983066.1"
                     /translation="MEKTFVLAPDSFKESMSAKNACEAMERGIRKVFPESKVIQVPMA
                     DGGEGTVDALVDGINGTKIEVMVSGPIPSEKIKAYYGLLADESTAVIEMAEANGIELL
                     AENKRNPLLTSTYGTGEMIKDALDKGVKKIIIGIGGSVTNDGGAGMAQALGVQFLDKN
                     DKELPVGGGALSELAKVDVSTIDPRLKETEVVIASDVTNPLTGPNGASFVFGPQKGAT
                     PDMVKKLDENLVHYAAVIQKNLGIDIKDQPGSGAAGGLGAGLLVFTGAKMESGVDLVI
                     QLTHLEEKIVQADYVFTGEGGMDFQTKFGKAPYGVAKIAKRYDKPVFACAGYIGEQVD
                     VLYEEGMTAIFGILDQAGPLKQALQAGESNLERTVENIVRVLNVCGG"
     gene            5594..6607
                     /locus_tag="NOB43_002229"
     CDS             5594..6607
                     /locus_tag="NOB43_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983067.1"
                     /translation="MSNLLTKEQANMIVSKLMADIPYNINIMNEQGFIIASGKEYRIG
                     ERHRGAERAIKQGEMVEIFKDTSLEKRGTNEPIILNGELLGVVGISGDPEEVRPFTKL
                     VKSIVLLLVEELNEFRKKEKKNQLKADFLKELLSIKDCYSEEMVHQALDDYGINLLRT
                     NRCIGSLEQETLRSCFPLHEVFEWYGMYIVFIDGNTIIDDDLSGLIVSSEQWNLGQGM
                     NEVDNTFLYLKFFQIPINKVFFSEDLYFIHLFDFSIKLDKNLLKKVESIYDEYYETLI
                     YFSSNNGNVKEVSEKLHIHRNTLNYRIQRIQELTRKDPKNWSHLWILMYHLAYCFKVK
                     FRT"
     gene            6999..8198
                     /locus_tag="NOB43_002230"
     CDS             6999..8198
                     /locus_tag="NOB43_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0983068.1"
                     /translation="MRDQTSGKMIRFYYTSLQFLYWMMFCSVYGFATLFLIYFKIDPA
                     KIGGILALVNIVSTVLQPFISQVIIKKRKIPLITVLKTMTAGLGVILLAGVLLPNLPI
                     ITYILGGILVVSMQSFLNALAFEYSNTGYRINFGFSRAGGSFSYAVTSFLLGQLLAIY
                     SAAILPILVIVEAVVFFVILHLLPDVKNQEVFPMTKEQDRPVSLRKKYPFLILLFLGF
                     SFLFTFHTMINSFLAQIFENIHGGSKEVGIALMIAALCELPGMIFFEQLVKKKSSKFW
                     LSIASISFAVRGFMMLLAGSILMMEMTHLLQAFSFALFIPASAYLFNQFLADDDRVFG
                     QTMIIIATTLGGVIGNVLGGSLLQHFGVWEMLIFGTSFAVLGALLTILGIRKIPKTGN
                     DSDSLVE"
     gene            complement(8693..9451)
                     /locus_tag="NOB43_002231"
     CDS             complement(8693..9451)
                     /locus_tag="NOB43_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0983069.1"
                     /translation="MDTKLSESEKYLWDFIQSHILEIPSYSIVKLSEYANVSTATVVR
                     TMKKKGYEGFTSFKHSLKEKENTNINFAALDKVDEGIKTAILKNEQEVIRTINMVESG
                     NIEDAIQRIKAARRIMIFARGFSELIAQEMMVKFQLTGKYCEMHTDPNIIKNISRKLF
                     KDDIVIFVSLNGETKELITAAENCYKAEIGTILLTANRHSSLMEHIEIPFVGFKSEGS
                     FFPDYEVRSRLPLSILARILLDSYALRTSGFTQH"
     gene            9619..10554
                     /gene="pfkB"
                     /locus_tag="NOB43_002232"
     CDS             9619..10554
                     /gene="pfkB"
                     /locus_tag="NOB43_002232"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCI0983070.1"
                     /translation="MSVYTCTLNLAIDLFIETDEMKPSQVNRTNDDDIQANGKGVNVS
                     LIMKQLGIDSTALGFKAGFTGNYIEDYLHQKDISTDFISVPGMTRINVFTQVNKTNEE
                     FKLVNKGPEIPQEQIKTFLNQIQKLQADDYLCVSGSLPRGVSPEILIDISRICFENKV
                     HLIIDSSYPEIIDCLPYQPFLLKPNEEELQSWYNVELSDREGYIHYAERLIADGAKNV
                     LLSLGGEGGIFLNKDIVYSGNSPKGKVVNTACAGDTLLGTFLAGYLKGEQVDINLKKS
                     LAAGSSTAFRKGLTDFSDVAELEKQIEIKEGASKK"
     gene            10551..11996
                     /locus_tag="NOB43_002233"
     CDS             10551..11996
                     /locus_tag="NOB43_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0983071.1"
                     /translation="MTTYKIVAATGCPTGIAHTYMAQEALEQAAKRKGVSIKVETHGQ
                     VGIENELTPEEIKNADAVIIAADKDVQAERFAGKRVIDVPVSKGIKDADQLIEDALAG
                     KGSIIAENKTVDAAGEKAEMGVAAGIGHSIYKNLMNGVSHMLPFVVAGGVIIAISFAI
                     WGVYSFDPNDPTYNPTAAMLKGVGDAAMGMMVPILAAYIAEGIAKRPGLVVGFVGGLL
                     ANSGGAGFLGGIFAGFLAGYFILLLQKVMKGLPKQLDGLKAIFLYPVIGVLFVGVVMS
                     LLANPMEAVNQGMMNFLAGFQNSNPLILGIIVGCMSAFDMGGPVNKAAYVTGTALLAQ
                     GNHTFMAGVSAACIAPPLITGFAVLFFGKYFDTNDRNAGLVNFILGSTHITEGAIPFA
                     AKDPLRVLPTMMLGSSIAAVLTYMFGVQVPAPHGGFLVLPVVTGKVAWVGSILLGSIV
                     GGVILGLIQKRSVEKREAEAATVEMKEETNN"
     gene            12024..12479
                     /locus_tag="NOB43_002234"
     CDS             12024..12479
                     /locus_tag="NOB43_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0983072.1"
                     /translation="MTLIKTNKVFMNKNFTTQDEVMNFLADQSIVLSISEDRDAVYEK
                     LMEREEESTTGMMDGFAIPHAKDASIKDADIVIVRLNGKVDWKSLDGEGTDFVIALFI
                     PDSEAGTTHLKFLSQVARLLMHKDVTEGLKQAQSAEEIAELLNQKLEEN"
     gene            12498..13472
                     /gene="lacD"
                     /locus_tag="NOB43_002235"
     CDS             12498..13472
                     /gene="lacD"
                     /locus_tag="NOB43_002235"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI0983073.1"
                     /translation="MPLTEKKKTYIRQLSNESGIISALAIDQRGALKKMIGKFQNQSA
                     TDEQIINFKKIISSELTPYASAILLDPEYGLPAAEVRDKNAGLLLAYEKTGYDASTPG
                     RLPDILSIWSVKRLKEQGADACKFLLYYDVDESDDINDQKKAFMERIGSECVAEDLPF
                     FLELVSYDANDPDTSSKEYALKKPHKVNEMMKEFSKPRYGVDVLKVEVPVNMNYVDGY
                     TKNEVAYTKEEAAAYFKEQSETTNLPFIFLSAGVTAELFQETLKFAKEAGSTFNGVLC
                     GRATWANGVEPFVTKGEYAAKEWMQTQGRKNIEELNNVLKETATAIKL"
     gene            complement(13582..14067)
                     /locus_tag="NOB43_002236"
                     /pseudo
     CDS             complement(13582..14067)
                     /locus_tag="NOB43_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364878.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
BASE COUNT         4434 a         2288 c         2987 g         4462 t
ORIGIN      
        1 aagtgaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat
       61 cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt
      121 ctagcttaat ttgacaaatc atattatatt ggacatggtt tggggcgtgt agtgatgccc
      181 atacattttc tcaatcaagt ctgcgatttc cgacatggta ataccttttc ggaagaggtg
      241 aatgacggtc tcatctaacg tgtcattcgt ccgtctataa gcaggaacag tctgttgctt
      301 gaactcgcca ttgcggtcgc gcggaatctg gagatgaagt tccccatact cggtcttgac
      361 cgtacggtca taggagccgt tacgagaatt acccgtgtta aaaccaatgc gatcatactt
      421 ttcgtaatcg aggaaagccg ttaactccgt tttgagaagc gtattgactg ctttctccaa
      481 atggacacgg aataattcat tcaaatcgcc tttgttcgct agagtcttta gaatttctgt
      541 agtaaaatcg ttcataggga agtcctctct tctgggctct ttgtcaataa ggactgatga
      601 agctgtgcaa aatcaaatct gggtcaggat gaacctcatt ctggctcaga ttttttgtta
      661 tttcactttg attaattgat tgatcaaaaa gattctaatt ctcatgttct caaatgattt
      721 aaatccgtag gatactcgtt tcattgtctt tatatgggta ttctttgctt ctatttttcc
      781 attagaataa ggatagatca tcgcattggt gatgccttct tcataggtca gaagattttg
      841 aagtttctca cgaaaggcat catctaacgt ttcaggaagt tcttccaata aagagaaaaa
      901 taagtcaggg tctttgtctc gaaaggcttc tactaactca tgaaaaaagg gatacgcctc
      961 cttcaggggc gtggagaaac caagcaatcg gtcaatcatc atcgcttcag taaaaaatgg
     1021 gtatttaggc gctcggaaac ttttccatgt tttgtattca taatggttaa tgtttgaacg
     1081 tttttttaac agaaagcgcc agttcttttt caacttttca gcctgccttt ttttacctgc
     1141 cttacgcagc tcattcattt cacggatacg taaatcgttg aatgcctgat ttatatgttt
     1201 gacaatatga aatcgatcaa tcactacttt cgcatttgga agaacacgtt tggtgagctg
     1261 gaaataggcg gcgttcatat ctgtgattaa aaattctact tcttctggat tggtgcaact
     1321 taagaaatag cttgttaatc gaggtaattt acgcgtaggc aagatatcaa ttaatttacc
     1381 tgtttcgcca tctgcgcaaa taaagctcat tttatcttct atagaagcgt gcgaacgaaa
     1441 ctcatcaacc atcaatactt ttgggagaat cctcttagag gactttggta aatagctttt
     1501 aaactctttc aatatacgaa taacggtggt caaagatacc tgacaacttt tcgcaataaa
     1561 agataaagac actttttcag tcagtaaaga agtaatttta tatctgacat gattcgcaat
     1621 ggaatgtctg gggcggacaa aataactttg agcagtccaa tgggttcgac agtttttaca
     1681 ggtatagcgc tgctttttta agcgcataac cattggcata tgattgtatt gttcaaagcg
     1741 gacaatggtt tccttcttgc cgtttttcac cacaattgtt ttcccagttc catctaccac
     1801 agtagaacca caattgctac aggcacaagg agcaggtgag agaatggcat cgacaatcag
     1861 agtcttttcc ttctgaaagg tctcataaga gacccctgta atcatcaaat ttttatctat
     1921 taatctcagc atttttttga tagaatcatt catatagcat atcgtcctct cagtggttta
     1981 ttttgtcgtg atttaatcat actagagaac gatatgtttt ttaatatcta aaatgaaaat
     2041 gagactgaag aatcaattct gattcatcag tctcataaat tatagagcca caaaactctg
     2101 tggtcttttt ttgtagtaaa ggaggaattt ggagtggcca aactagatga agaatttgct
     2161 tttttggtat tgtcgatcat atcggagatt cccaaaggca aagtagctac ctatggacaa
     2221 attgccgagt tggcaggata tcctcgcaat tcccgtttag tcggtaaagt attgagccac
     2281 gccgaatatt atggtcgcta tccttgtcaa cgagtagtga atagtcaggg agaatgtgcg
     2341 aaaggttggc cggaacagcc gttactattg caagagaggg tattattttt cgcgagaatg
     2401 gacgagtgga tctgaaacgc tgccattggg atggagaaga gtgatctgta aaggatcatt
     2461 cactttaagc aatacagata tgatgaaata aaatatctat gaattttttt gcgttgcaat
     2521 ggagagattc tttgggagtt tgattctaaa ataaatcata tacaatgggt tatttagtgc
     2581 ccgattttgt taggagtata ggcaaaaaga attagtagtg aaaatcagta ttgtatttgg
     2641 gatatattct tttatttaat atgagttagg tccttagaac taaaagaatt aagagattga
     2701 ttgactttgt aaatagtaaa atacctaata agtatcaatg agttcccaaa tcgtatctag
     2761 ttgaatagaa gaaatttcta ttgaatacta tgtgattcta tgaatttatt taagttgtct
     2821 aaaatagtga aattctgaat ttatattatc gatatgtgca aatgaacaaa taacattgta
     2881 aatataccaa ttttatttat gaaataaagc attaaaatga aaacgtaaac aattaagaaa
     2941 ggatgtttga aatggatgga attacaatac cgtggtatgc ggcgattatt ggtttgattt
     3001 ttgcagtttt tttgattttg aaaaaaatga atccggttta ttcattattt ttaggagcaa
     3061 ttatcggatg tttgatcggc ggagcatcac taagcaatac cgtggatata ttagttacag
     3121 gaacacaaag tattatgggg acagcaattc gtgtgttggc agcagggatg ttggcaggag
     3181 tgatgatgga gtcaggcgca gcagaatcca tcgcccatgc aatcgttaat aaacttggaa
     3241 gtaataaagc aatcttttca ctagctctgt caacaatgat cattacagct gtgggcgtat
     3301 ttattcctgt cgcagtattg atcgtagcgc cgatcgcttt gtcagtcgga aagcagacag
     3361 gtatcagtaa attagcattg ttgacagcat tgtctggtgg cggcaaagct ggaaatatca
     3421 tttcgcctaa tcccaatact atcgcagctg ctaatgggtt taaattagat ttaagcaatg
     3481 taatgattgc tggatttatt ccggcaattt ttggattagc aacagcagtt cttattgcta
     3541 gtttgattaa gaaaaaaggc ggtaaggtta aagatagcga tattcaagaa aaatcggaaa
     3601 aagaattgct tccattacgc aaagctttaa ttgcacccgt tttgtcaatc gttttattat
     3661 tgataaatcc aattggaacg atgcttcata ttcaggtgtt ggctgatttg aagatcgatg
     3721 cgatgtacat tttacctttc gcttcgatag tggggacgat cgcaatggga caagctagtc
     3781 aaatcagaga atattcaaaa tcggggattt atcgtgtgac agataccgtt ttgatcttga
     3841 ttggtgctgg tgctatagct ggtctgatct cagtttctga tttatcaaaa caagttgtcc
     3901 atttgatttc cattacaggg atttcgggta cattattagc gcccatctca ggtattttaa
     3961 tgggcttagc agtaggatca acttctacag cagtaatttt agcgactgga tcttttgggc
     4021 atgctattct tgaaaccgga accaattcgt tagcagcagc tgtaatggtt catacaggtg
     4081 caacggtgat tgatagtgta cctcaaggaa actatttcca cattacggct aacagtatga
     4141 atatgtctat caaagaacgg atgaaagtga ttccttacga aatctgtgtc ggtggtgtga
     4201 tgacgatcgt tgcaacgata ttatatggat ttattttaaa ataaaattgt agagatagcg
     4261 ttttgtcaaa tcttttacaa aaatatgaac ttgaaaaaat atttattgaa aataacaatg
     4321 aagaaggtaa attctgtttg aaaagaagat tttcagcaga attttgagga gaagaacaat
     4381 ggagaaaact tttgtattag caccagattc atttaaagaa agtatgagtg ctaaaaatgc
     4441 ttgtgaagca atggaacgag gaattcgcaa agtatttcct gaatctaaag tgatccaagt
     4501 ccctatggca gatggaggag aaggaactgt tgacgcacta gttgacggta ttaacgggac
     4561 aaaaatcgaa gtgatggtgt ctggaccaat tccatcagaa aaaatcaagg cttattacgg
     4621 gttgttagca gatgaaagta cggcagtgat tgaaatggct gaagccaatg gtattgaact
     4681 attggcagaa aacaagcgaa accctctttt gacctctact tacgggactg gagagatgat
     4741 caaagatgcc ttggataaag gagtaaaaaa aataatcatc ggtataggag gcagcgtcac
     4801 gaatgatggc ggtgcaggta tggctcaagc gttaggagtg caatttttag acaaaaatga
     4861 caaggaacta ccggttggag gcggcgcgtt gtcagaatta gctaaagtcg acgttagcac
     4921 tatcgatcca agactaaaag aaacagaagt cgttatcgct agcgatgtaa ccaatccgtt
     4981 gacgggtcca aatggcgcat catttgtttt tggtccgcaa aaaggagcta cgcctgatat
     5041 ggttaagaaa ttagatgaaa atttggttca ctacgctgcg gttattcaaa aaaatttggg
     5101 gatagatatc aaggatcagc ccggttctgg tgcagcaggg ggattaggag ccggactatt
     5161 agtttttact ggcgcaaaaa tggaatccgg tgtcgatttg gttatccagt taacacattt
     5221 ggaagaaaag attgtacaag ctgattacgt gtttaccggt gaaggcggta tggattttca
     5281 gacaaaattt gggaaagctc catacggtgt agcaaagatc gccaaacgat atgacaagcc
     5341 tgtttttgct tgtgccggtt atatcggcga acaggttgat gttttatacg aggaaggaat
     5401 gactgcgatt ttcggcatct tagaccaggc cggtccattg aagcaagcat tacaagccgg
     5461 cgaatccaat ttagagcgta cagttgaaaa tatcgtccgt gttttaaatg tttgtggagg
     5521 ttaaaagttg tgttatctat caaaaaaaga ttaaactaac tgtataacca gataattctt
     5581 aggacggtaa tcaatgagta atttattaac aaaagagcag gccaatatga tcgtaagcaa
     5641 gctgatggcg gatattcctt acaatattaa tattatgaat gaacaaggtt ttattattgc
     5701 aagcggtaaa gaatatcgta tcggtgaacg acatcgtggt gcagaaagag caattaaaca
     5761 aggcgaaatg gttgagatct tcaaggatac ttccctagaa aaaagaggaa ccaacgaacc
     5821 aatcatttta aatggcgaat tattgggagt agttggaatc tcaggagacc cagaagaagt
     5881 ccgcccgttt actaagctag taaaatcaat cgtactgctt ttagttgaag aactaaatga
     5941 atttcgaaaa aaggaaaaga aaaatcagct taaagctgat tttttaaagg agctcctttc
     6001 aatcaaagat tgctacagtg aagagatggt tcaccaggca ttagatgatt acgggataaa
     6061 tcttctgcga acgaatcgct gtattggatc attggaacaa gaaactttac gtagttgctt
     6121 tcccttacat gaggtttttg aatggtatgg aatgtatata gtttttattg atggcaatac
     6181 cataattgat gacgacctct caggtttaat cgttagctct gaacaatgga atttaggaca
     6241 gggaatgaat gaagtagata atacttttct gtatttgaaa tttttccaga ttccaatcaa
     6301 taaagtcttt tttagtgaag atttatattt tattcactta tttgattttt caattaaact
     6361 agataagaat ctattaaaaa aagttgaatc aatctatgat gaatattatg aaacactgat
     6421 ttatttttct agtaataatg gaaatgtgaa agaagtgtca gaaaaactgc atatccatcg
     6481 taatacacta aattatcgaa ttcagcgtat tcaagaatta actagaaaag atcctaaaaa
     6541 ttggtctcat ttgtggatat taatgtacca tcttgcttat tgtttcaaag tgaagttcag
     6601 aacgtaagaa ataagaatat gtatccataa taaatgtttg gatttacctt atagatataa
     6661 aaagaaacaa atcattctgc aggaatcgat tactcgattc ctgctttttt tacttccttt
     6721 gcagcaaaaa agtgctcgta atctaagcga tgttggatag tttttagaat atatatattt
     6781 tcttcaattc cagaaaaaaa tgaccaagct agtatgctaa aaaagtacga tgcttctatg
     6841 atcttttttc cgtctttatt aacagatgtt ttaattgatc aacgcatatt gtaatctacc
     6901 ctaatttcca tagttcttca ccacttttaa aaatagtaaa acccctacaa gtatgctata
     6961 gtaaattgct aaagaaaaac caataaggtg ggagatgtat gcgcgatcaa acaagtggaa
     7021 aaatgattcg tttttattat acaagtttgc aatttctcta ttggatgatg ttttgttcgg
     7081 tctatgggtt tgcgacattg tttttgattt atttcaagat tgatccagct aaaatcggag
     7141 ggatcttagc attggtcaat attgtttcaa cggtgcttca gccttttatc agtcaggtga
     7201 tcatcaagaa aagaaagatt ccactgatca ccgtgctaaa gacgatgaca gcaggattag
     7261 gagtgattct cttagctggg gtattgcttc cgaatttgcc gatcattact tatatcttgg
     7321 gtgggatttt agtagtttcc atgcaatcat ttctcaatgc gctggcattt gagtattcaa
     7381 ataccggcta caggatcaac tttggttttt caagagctgg cggttcattt tcttatgctg
     7441 taacttcttt tttactggga cagttgttag cgatttattc tgccgcgatt ttgccgatct
     7501 tggttatagt tgaagcagta gtgtttttcg ttattttgca tctgctgccg gatgtaaaaa
     7561 atcaagaagt ttttcctatg acaaaagaac aggatcgccc agtttctttg agaaaaaaat
     7621 atcctttcct gattttgttg tttttaggtt tcagttttct ttttactttc cacaccatga
     7681 tcaacagttt tttggcacag atctttgaaa acatccacgg tggcagtaaa gaagtcggca
     7741 tcgcattgat gatcgccgct ttatgcgaat taccgggaat gatctttttt gaacagcttg
     7801 tcaaaaagaa atccagcaaa ttttggctgt ctattgccag tatttcattt gctgtcagag
     7861 gattcatgat gctgctggcc ggttcgatct tgatgatgga aatgacgcat ctcctgcaag
     7921 cctttagttt tgctttgttt attccagctt cagcttattt attcaatcaa tttctggcgg
     7981 atgacgaccg tgtatttgga caaacgatga tcattatcgc cacaactctt ggtggggtga
     8041 taggaaatgt cttgggcggc agtctgctgc agcatttcgg tgtatgggag atgctgattt
     8101 tcggtactag ttttgcggtg ctaggtgctt tattaactat tttgggcatt cgaaaaatac
     8161 cgaagacagg aaacgatagt gattctcttg ttgagtagca taaaaatact tagatactag
     8221 ttttatataa ataacatata gtgattattg gtgtaattac aaaaaacgag aataacttaa
     8281 gtaagcattt ctaaataatt gagaaacctc atctaaaaag ataagaaaat atccctaata
     8341 aaacttctgt aacattttag ataactgatt gtaagctgaa taataaacta taaggagaca
     8401 gttagacggt ctcctttttt tgcgtattat aattctagaa ttgttggaaa ttgataataa
     8461 ttaacaagaa atattagaca ggaacttcga actgcttatc acattcttat tattatatat
     8521 ttgcgtaagt agtcctggta gtctcaatgc actattctat cttgaaacta agaagttata
     8581 gaaggagcaa tgatagaaag cacgagaata caaatagcga ttaaatattt ttctagacaa
     8641 ccttagttaa ttcacacaga tatattttag gtacagtctt acagatatag agttagtgct
     8701 gtgtgaatcc tgatgttcgc agtgcatagg agtcaagtaa gattctagcc agtatagaaa
     8761 gtggaagtct ggagcgtacc tcataatctg ggaagaagga gccttctgat ttaaagccaa
     8821 caaaaggaat ctcgatatgt tccatcaaac ttgaatgacg attagcagta agcaaaattg
     8881 tcccgatctc agctttataa cagttttcag ctgcggtaat caattccttt gtttcaccgt
     8941 ttagtgaaac aaagatcacg atgtcatctt tgaataattt tctactaatg ttttttatga
     9001 tattgggatc agtatgcatc tcacaatatt taccggtaag ttgaaatttg accatcattt
     9061 cctgagcaat caattctgaa aaacctcggg caaaaatcat gattcttcta gcagccttga
     9121 ttcgttgaat agcatcttca atattcccgc tttctaccat attgatggtg cggattacct
     9181 cttgctcatt tttaagaata gcagtcttta ttccttcatc aactttatca agagcggcaa
     9241 aattgatatt tgtattttct ttttctttta acgaatgttt aaaagacgta aacccctcat
     9301 atcctttttt cttcatagta cgaacgacgg ttgctgttga aacgttggca tattcactta
     9361 gttttacaat ggaataggag gggatttcga gtatgtgact ttgaataaaa tcccagagat
     9421 atttctccga ttcacttaat tttgtatcca tattttgcct ccgattagtt aggataattc
     9481 tattgtaaag cgggagtttc ctttacttca agtttattta atatattttg taaaagtttt
     9541 caatgaattt agtcatttat gaaaacattt acattcgatc ttgatacata atgaatatgt
     9601 aagaaaggag gagcgtaaat gtcagtttat acatgtactt taaacttggc aatcgacctt
     9661 tttatcgaaa cagatgaaat gaaaccatcc caagtcaatc gaacaaacga tgatgatata
     9721 caagctaatg gaaaaggggt gaatgtttca ttgatcatga agcaattagg tatcgatagt
     9781 acagctttag gatttaaagc aggttttacc gggaattata ttgaggatta tttgcatcaa
     9841 aaagatatta gcactgattt tattagcgta ccgggaatga ctagaatcaa cgtttttaca
     9901 caagttaata aaaccaatga agaattcaaa ttggttaata aaggacctga gattcctcag
     9961 gaacaaatca aaacttttct aaatcaaata caaaagctgc aagctgacga ttatttgtgt
    10021 gtttctggca gtttgccgcg aggggtctca cccgaaattc ttattgatat cagtcgtatt
    10081 tgttttgaaa ataaggtcca tctgattatt gattcaagct atccggaaat aattgattgt
    10141 ctgccgtatc agccgttctt attaaaacca aacgaggagg aattgcaatc ttggtataat
    10201 gtcgagctta gtgatcgtga aggatatatt cattatgctg aacgcttgat tgccgatgga
    10261 gcgaaaaatg ttctcctttc tctaggagga gagggaggaa tatttttaaa taaggatatc
    10321 gtttattctg ggaattctcc taaaggtaaa gtagtcaata cagcgtgtgc tggtgacact
    10381 ttgttgggaa catttcttgc aggatattta aaaggtgaac aggtagatat taatttgaag
    10441 aaaagtttag cagctggaag ttcaaccgct tttcgtaaag gattaacaga tttttcggat
    10501 gttgcagagt tggaaaaaca aatcgaaatc aaagagggag cgagtaaaaa atgacaactt
    10561 acaaaattgt tgccgcaaca ggatgtccaa caggaattgc ccacacttat atggctcaag
    10621 aagcattgga gcaggcagct aagcgcaaag gggtatctat caaagttgaa acccatggtc
    10681 aagtagggat agagaatgaa ttaacaccag aagaaataaa aaacgctgac gctgtaatca
    10741 ttgcagctga caaagatgtt caagcagaac gtttcgcagg taagcgtgta atcgatgtgc
    10801 ctgtcagcaa ggggattaaa gatgctgacc aattgatcga agatgcgttg gctggtaaag
    10861 gttcaatcat tgcagaaaac aaaacagttg acgctgctgg tgagaaagcg gagatggggg
    10921 ttgcagcagg cattggtcac agtatttata aaaatctcat gaacggtgtt tctcatatgc
    10981 tgccgtttgt agtggcaggt ggggtaatta ttgcaatttc gtttgccatc tggggtgtgt
    11041 actcttttga tcccaatgat cctacttaca atccgactgc cgctatgtta aagggtgttg
    11101 gtgatgcggc aatgggaatg atggttccta ttttagcagc ttatatcgct gaaggaatcg
    11161 ctaaacgtcc tggtttggtt gttgggtttg ttggcggact gttagccaat tctggcggag
    11221 ccggtttctt aggcggaatt tttgcaggtt tcttagcagg ctactttatc ttactattgc
    11281 aaaaggtcat gaaaggcttg cctaaacaat tggatggtct gaaggcgatc ttcttatatc
    11341 cggtgatcgg tgtcttgttt gttggtgtag tcatgtcttt attagcaaat ccaatggaag
    11401 cagtcaacca aggaatgatg aatttcttgg caggattcca aaattctaat ccattaattt
    11461 tagggattat cgttggctgt atgtcagcat ttgatatggg aggtccagtc aataaagcgg
    11521 cttatgttac agggactgcg ttgttggcac aaggtaacca tacatttatg gcaggggttt
    11581 cggcagcttg tatcgcgccc ccattgatta ctggatttgc cgtactgttt tttggaaaat
    11641 atttcgacac gaatgatcgc aacgctggtt tagtcaactt tatcttgggc tcaacgcaca
    11701 ttaccgaagg agcaattcca tttgcggcta aagatccgct gcgtgttctg ccaactatga
    11761 tgctaggttc atcaattgct gctgtactga catatatgtt tggtgtccaa gttcccgcac
    11821 ctcatggagg ttttctagta ttacctgttg ttactggtaa ggttgcatgg gtagggtcga
    11881 ttttacttgg ttcaatcgtt ggcggagtaa ttttagggtt gatccaaaaa cgtagtgtag
    11941 aaaaacgtga agcagaagca gctactgttg aaatgaaaga agaaaccaac aactaaaggt
    12001 tattctagaa agaaggattt caaatgactt tgatcaaaac aaataaagtt tttatgaata
    12061 aaaattttac gacgcaagat gaggtaatga acttccttgc agatcagtca attgtcttga
    12121 gcattagtga agaccgagat gcagtttacg aaaaattgat ggaaagagaa gaagaaagca
    12181 cgactggtat gatggatggt tttgccatcc ctcatgccaa agatgctagt atcaaggatg
    12241 ccgatattgt gattgttcgg ttaaacggta aggtcgattg gaaaagttta gatggagaag
    12301 gaacggattt tgtaatcgct ctgtttattc cagattcaga ggctggaaca acccatctaa
    12361 aatttttatc tcaggtagcc agacttttga tgcacaaaga tgtgacagaa ggtctgaaac
    12421 aagcccagtc tgctgaagaa atagctgaac ttttaaacca aaaattagaa gaaaactaaa
    12481 aaggaagtag tgaaatcatg cctttaacag aaaaaaagaa aacttatatt cgtcaactaa
    12541 gtaatgaaag tggcatcatc agtgcgttag caatcgatca acgtggtgcc ttgaaaaaaa
    12601 tgatcggtaa atttcaaaat caatcagcaa ccgatgaaca aatcatcaat ttcaaaaaaa
    12661 tcatttcttc tgaattgact ccatatgctt cagcaatctt attagatcca gaatatgggt
    12721 tgccggcagc cgaagttcgc gataaaaatg ctggtctgtt gttggcctat gaaaaaactg
    12781 gttacgatgc ttcaactcca ggacgtttac cggatatttt atctatttgg tctgtaaaac
    12841 gtctaaagga gcaaggggcc gatgcttgta agttcttgtt atactacgat gtagatgaat
    12901 ctgatgatat caatgaccaa aagaaggcgt ttatggagcg gattggttct gaatgtgttg
    12961 ctgaagattt gccatttttc ttagaattgg tttcttatga tgccaacgat cctgatactt
    13021 cttcgaagga atatgccttg aaaaaaccgc ataaagtaaa tgaaatgatg aaggaatttt
    13081 ctaagcctcg ctatggagtt gacgttttga aagtggaagt tcctgttaat atgaactatg
    13141 tggatggtta cactaaaaat gaagttgctt ataccaaaga agaagctgct gcttatttca
    13201 aagaacaatc cgagactacc aacctgccat ttattttctt gagcgcagga gtaactgctg
    13261 aattgttcca agaaaccttg aaatttgcaa aagaggctgg ctctacattc aatggggtac
    13321 tctgtgggcg cgcaacttgg gcgaatggtg tagaaccatt cgttactaaa ggtgaatatg
    13381 ctgccaaaga atggatgcag acacaaggac gcaagaacat cgaagagctg aataatgttt
    13441 tgaaagaaac agcaacagct attaaattgt aagaaagctt taactataac cttaagtttg
    13501 taacctaatg atttttaata atcaatttga gcttttaaat aaagaattgg aagcgtcccg
    13561 acgcttcctt tttcgtttgt cttaaggcat gataggttct atgttgtcgt tcaataagcg
    13621 caagaaggtc agcatttttt tcttagagta tgcaaaattg ctttctaccc aatgatttaa
    13681 aacggagagg cacccttgga tatggtaaat ggtgaagtaa cgcatttctt ctgtgatcac
    13741 ggtttttttg tcttcttgta gccagatttt taaataattt tcttcgatca gattatttaa
    13801 tctcttttgg aattggatat ctccgtggtt gataacgaat aacttgtaca cgaacgtatt
    13861 tgtatagaca tagtcgatca aatgagcgta tagatcctcg tagctgtgtg tcgtgtcata
    13921 ggaaatgatt tcatccaagt cttagaaaaa gctattttct agcttttcat aaagatcata
    13981 gatatccgta taatgtttat aaaatgtcga acggtgaaga tcagcagttt cggtcagttc
    14041 acggatagtg atgttttgaa tttttcgcga attgtaaaat taagttagaa aaataaaaag
    14101 gcatttatgg tacactcaaa ttgtatttcc gacgaaagaa aacaaaggag tgtaaccata
    14161 aatgacctac a
//
LOCUS       DAIGTA010000064        13945 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.067, whole genome shotgun sequence.
ACCESSION   DAIGTA010000064 DAIGTA010000000
VERSION     DAIGTA010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.067"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            137..310
                     /locus_tag="NOB43_002237"
     CDS             137..310
                     /locus_tag="NOB43_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983074.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="NOB43_002238"
     CDS             950..1423
                     /locus_tag="NOB43_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCI0983075.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="NOB43_002239"
     CDS             1432..1659
                     /locus_tag="NOB43_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983076.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="NOB43_002240"
     CDS             2295..2666
                     /locus_tag="NOB43_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983077.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="NOB43_002241"
     CDS             complement(2922..3164)
                     /locus_tag="NOB43_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0983078.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="NOB43_002242"
     CDS             complement(3196..4098)
                     /locus_tag="NOB43_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0983079.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4111..4299)
                     /locus_tag="NOB43_002243"
     CDS             complement(4111..4299)
                     /locus_tag="NOB43_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI0983080.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="NOB43_002244"
     CDS             complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="NOB43_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI0983081.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4914..5807)
                     /locus_tag="NOB43_002245"
     CDS             complement(4914..5807)
                     /locus_tag="NOB43_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0983082.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5885..6808)
                     /locus_tag="NOB43_002246"
     CDS             complement(5885..6808)
                     /locus_tag="NOB43_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0983083.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6857..7207)
                     /locus_tag="NOB43_002247"
     CDS             complement(6857..7207)
                     /locus_tag="NOB43_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0983084.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7240..8142)
                     /locus_tag="NOB43_002248"
     CDS             complement(7240..8142)
                     /locus_tag="NOB43_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI0983085.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8135..8992)
                     /locus_tag="NOB43_002249"
     CDS             complement(8135..8992)
                     /locus_tag="NOB43_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI0983086.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9326..10135
                     /locus_tag="NOB43_002250"
     CDS             9326..10135
                     /locus_tag="NOB43_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0983087.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10175..10672
                     /locus_tag="NOB43_002251"
     CDS             10175..10672
                     /locus_tag="NOB43_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0983088.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11057..11130)
                     /locus_tag="NOB43_002252"
     tRNA            complement(11057..11130)
                     /locus_tag="NOB43_002252"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11094..11096),aa:Ile,seq:cat)
     gene            11317..11640
                     /locus_tag="NOB43_002253"
     CDS             11317..11640
                     /locus_tag="NOB43_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983089.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11804..12058
                     /locus_tag="NOB43_002254"
     CDS             11804..12058
                     /locus_tag="NOB43_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983090.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12128..12373
                     /locus_tag="NOB43_002255"
     CDS             12128..12373
                     /locus_tag="NOB43_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983091.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12449..12814
                     /locus_tag="NOB43_002256"
     CDS             12449..12814
                     /locus_tag="NOB43_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983092.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12875..13438)
                     /locus_tag="NOB43_002257"
     CDS             complement(12875..13438)
                     /locus_tag="NOB43_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983093.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4088 a         2577 c         2303 g         4977 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg atgtttcctc ctaagattta aaatagtgat ctaagatttt
     4141 cgtttgtttc agataaaaac cgatagcgac gccgatcgct gccatgatca agatcaataa
     4201 ggtcttgaaa aagcccacgg tgatccataa aacggctaat atcaatccaa gtaccccaaa
     4261 gatgataggg agcttgtatg tcgaaaatag ttctttcatt tttggtcccc ccctattcta
     4321 ctcgtttgcg gtcattgctt cgtttagctg gttcttcaaa gcctgtgtat ttcaccgata
     4381 ctttcactgg ctcttttgtt cccaatatgt gttgtacttc attttcgatt tctttcatca
     4441 atgttcctgt tttaccaatg agtgctgaag ttcgtttcaa ctcccctttt acattgacgg
     4501 cgatcttgtt tttcgttgct ttgacattta cttttggtga atggatgaat tcatcttcat
     4561 gcaagtgaga acgaaccatt ccttcaattg cttttttatc caacgtcaac tccccatcac
     4621 catgtttcag tagaaagttt ccgattgttt ttggataaaa caggaaaaca agtaacgtga
     4681 taattgtcaa aatagcaaat gcaacggcaa gccaaaatac atattgttgc acgtatgaat
     4741 tagtgatgga aaagaatcga aacttctcta gctgaaaagg caatggatag gttgcactta
     4801 atagtatcgc aaacaaaagc acagatagca aaagtaatgt tccgatcact ccgatcgttt
     4861 ttacaccttt attcattttc gcacctcctc ataggggtga aacgatcaac ttcttataag
     4921 ttgatcgctt ctccaccagt tactccgtaa atttgggctg taacataact tgctttattc
     4981 gatgctaaga aaacataaac tggtgctaat tctcctggct gacctgcacg ttctagtaaa
     5041 ctttgctgac caaattcagg gatcgaatca gaaggttgtc cttcgtctag ttgtaatggt
     5101 gtccagattg gaccaggtgc tacaccattt acacggattc ctttaggtgc aagctgtttt
     5161 gctaaaccga tcgtaaagtt agcgattgaa gcttttgttg ctgcgtaatc taataaatgt
     5221 tcgcttggat tgaatgcttg aacagaagtt gttgttacga ttgctcctcc tgctgggata
     5281 tgcggaacag cttctttcac taaagcaaac atagcgatga tgtttatcat aaatgtgtct
     5341 ttgacttgct caagtggtaa ctcagcaata gactgacaag aaatttgctg tcctgcgttt
     5401 agtaccatcg tatctagccc gccaagttca ctcacggctt tatctatgat ttctttaggt
     5461 gcttgttcgt cacgaagatc aaaaggtagt aagacaatct tacgtcctgc atctttcacg
     5521 tattttgcta cttcctctgc atctttttct tctcctggga agaattgaag agcgatatct
     5581 gccccttctc tagcaaatgc aatcgctgct gcacgaccga tccctgaatc tccaccagtg
     5641 attagtacac ggcggttttc tagttgatta ttgccttcat aggattcttc tccacaatca
     5701 ggaacaggaa tcatattctg ctgtaaagct ggtgtatcct gatcttgttt aggaaatttc
     5761 tccgtatggt acaagtttcg cgggtcgatt aattttggtt ctgtcattgc tgtattcctc
     5821 ctagttttta aattgtattg ccaaaacaaa tttctttgtt tgatacctgt tttaaataga
     5881 ttctttaatt tgtataatct ttccggtata aatggtaacc taaaactact gctgctatca
     5941 aagagccaaa gactacgagt ataaagccta gagcagaact tttacccggt aatcctcctg
     6001 tattcattcc ccaaatccct gcgaacaacg ccggaacgga aatgattaat gcagctgaat
     6061 ctagatattt catgatatga tttagattat tgtccatcat cccgttgaat agatcaccaa
     6121 tactctctaa taaatctcga tagatctcga tcattttttc tgtttgtcgc tgtctcaaat
     6181 ggacatcata gagtagctgt tcatcgtcta aacgtttgat gaaagtttca gaattccata
     6241 attgatccat tgtttcccgt tgatctctta aggtatgatc gatatatacg atgtctcttt
     6301 caagatctgc ctgtttatac agttcttcat tttccgttgt tttacgagct gctttatcca
     6361 aagcgtcaat tcgctttttc atctctctta gttctttcac gtaatgggtg taaatatcta
     6421 ataatgtata cgtgatgatc ttttcaaacg agtttaaatg atttccatgc tttgtcagca
     6481 gccgatccac aaattcggtt tttctatcga tacaagtaat caagagatta tcggaaagta
     6541 caaaagatat tggcgttaat tttttttcga tacgattatc tgactgatct agattaatca
     6601 ctaccaaaga aaatggatgc tctagtttcg tctcataaag gcgctccatc cgagaaactt
     6661 cttccggata ttcggttcct acgaaaatat catcaggaag ctcgaattct tcgattgctt
     6721 gctcaatctc ttcgggcttt gcactatcaa gtacgagcca attatatttt ttttcatctg
     6781 tttctattac attcttttct tcatccacaa agtagtatct caatgtatac ctcctttttg
     6841 gactttctcg aaactattag ctgaagaagc agttctttaa tttgatatta taatcgagta
     6901 ctgcgatttc attttctaat gaaaagctgt caagctgttt gttgaagtcc atgttcaatc
     6961 gtttaccgaa ataattttgc tctaatttag atgtatagat gtccaataat ggatgctcta
     7021 ttttagtcgc atattctcca aattccgaaa caaaaggaat gatttgaaaa aagctgcctt
     7081 ttgcaaaagc acctttgtcc cttagaaatg gatcggaatc attgataagc gcgagtgcga
     7141 tttttgtatt ttccccaacc ttttcaatta acgtctctac tgcattttta gacattgtaa
     7201 tttccattcc tactccccct cttcagttgt tgtcttctat tatttaacaa ctacatctgt
     7261 ttttggttga acttttgcat attttggata tttagggaat ttagctacac aacggaaagc
     7321 cgtcatccct gcatattttt cgtaatattt cttcgttggc ccttcaaaat ccttgctcca
     7381 cggtttcaca tgtcctgaaa aatggataat gtaaggattg ttgcgagttt cttcgtattc
     7441 acgttcacct gctgctgttg gatgtttttt tgcttttgcc atgatatagc cttgtgcatt
     7501 ccaacgcgga tgaagtggta accaacggtc atgtaagata gcatttaatg catcttggtc
     7561 atggaatcgt aatttttctg gattatgttc gatgaaatct aatacttttt gcgtaatatt
     7621 ttcatctaac cattttttca cattgatcag catcaaacct gagttgaaat aacgcattga
     7681 tttagctgaa attttcattt tttccagtcg ttgatggaac ccagcgtctt caacagctgc
     7741 tacgattgaa tcaccgaagt caagacgcca taatttagag atatcttgta aagcgatcat
     7801 gtcgcaatcc atatataaga tacgttcaac ttctgtgccg cggaacaatt ccggaatcgc
     7861 aatacgataa taagctgttt ctggaatacg atcgctgatt accacatttg taaagaattc
     7921 tttattgatt ttcaagaatt ccacatctga gttcattcgt gcgtttttca ctgagaagcg
     7981 taaaagctgt ttactttcaa aatcgatatc atcgtcaatc acatagaacc gaacaaattt
     8041 agacgggttg caattatcta atactgagac aaataatgca gctaaatgtg gtacgaattt
     8101 tgtgttacaa cttgcgacta ctgctatttc ttttttattc attgatctcg cctactttcg
     8161 ttagagtact gtgtgctaat ttttttaagt ataaattggt atacggatga tctttcaacg
     8221 tattccaagg tttatcatgt cctgtaaagt gaacgatcga aggtttttca tttccttctt
     8281 tatactgacg ttcatatttt tcatttggtg ctggatgacg ttcaaaaatc agcgaagtct
     8341 gcatgttcca ttttggatga agttgttccc aatcttcata aagtacagca ttcaaagcat
     8401 cttggtcgtg atagatgatt cgatcgccat tttcactgag gtaatggata gttttttctg
     8461 taatttcttt tttattccat tgatcaatgt caatcaccat cactcctgaa ttgaagtaca
     8521 agtcatcgga atcgattcct aatctttcca aagctttcac ttggcctgga tcgataatag
     8581 cgccgattgt ttttccattt aacggctcat catatagttt tacgatatcg tctagtacta
     8641 acacatctga atctaagtaa aggactttct tataatcctc tttagctaat aagtttggta
     8701 aagaaattct taagtaagcg gtagttgtga tatggtcact gactaggaag tcttcgtaga
     8761 tatctttttc cactgtcagg aattggatac ttgcattact tgaatattta tttaccgttt
     8821 cttccaatcc ttctttacta tattctgata gaccatcgtc aatcacataa aattttatgc
     8881 gtcttgtttt attgcaattt tctaatgcag ttgcgatcat cacgctcaag taaggagcat
     8941 aattttcgtc tgaagcagtt accacaggaa ctacgccgta tctcttctcc atcaaaatca
     9001 ctcctttttc taatcttttt ctaacctgtt ctacatctag aatattcctc atttggtttt
     9061 aaagcaaaat atatgctttg ttttcattga atattttaaa atttttttat cacaaaacgc
     9121 atcggtaagc gctaactatt cgtttttcat ggctttttat tcaaaggtat tgaccaaaaa
     9181 ctactatata tagccacctt tttcttaaga atgttttttg aaaaaattca taatgacaaa
     9241 gcaagttagt ttcatttttt taaattctca tttaatctta aggtaacagg aaaatagata
     9301 tgtaaaaaga aagtaggaag ataaaatgaa actagcagcg attgatttag acggtacctt
     9361 gcttgatcga aatggaaaga taccagaaga aaatatccaa gcacttcgga aatttgatga
     9421 aaatggcgga atcgtaaccg tcgctaccgg aaggaacagc atttctgcta aagatatttt
     9481 ttccgaatta ggaatcggtg gctatttgat ttcttccaat ggttcactga ttgctgaaat
     9541 gaaggatgga aaaatggcga aagttctcag acgttcaaaa atagatagcg atacactgag
     9601 aaaagccttc ttctatgctc aagaagcgaa aatatccatc attgctagcc gagaaaccca
     9661 agatgatcag ctgacattcg atgaatcaaa tctagtcaaa gatgaccctt attatgaaca
     9721 tttcaattta cagaaccatt cttttgatca aattttaaat atgttggaag atccttctct
     9781 tagctatctt aaattagcat taacagataa gagtgaagaa aaactacaga agctacaaag
     9841 agatctgcaa gcagatggta tccaatcagt attctctgat ccgcatttct tagaaatcac
     9901 gcctacaggt atcactaaag ctcattcact tgtttttctg gcggattacc ttggaatcga
     9961 atcgagtgac atcatggctt ttggcgatca agaaaacgac attgctatgt tgaattacag
    10021 cgggttgagt attgcgatgg ggaatgcaca gcgacaagta aaagaaattg caaaccaagt
    10081 aacactgacg aatgaagaag ctggtgttgc ttatatttta aaaaacttct attaaaaaga
    10141 ataaaatgac gatatgaatg taggaggaaa gaaaatgtta gttattattg atatgcaaaa
    10201 tcatattctt gatccaaaca gcgaatttta tattccagag tcagatcaat tggcagaacg
    10261 tattgctcaa agattagcta aagcacgcca aaataatgaa tatattctct tcacacggga
    10321 tataccagtt gaactgaagg acaaagaaga agaacgagaa gatttgcaat tgatccctct
    10381 tctttctcca caagaaaatg aacgagtgat taaaaagtat tactttacga ttccacctga
    10441 aactttagct gaaatccagg aaactttatt tgaaagcaaa gaagaacaaa aagagatcga
    10501 agtagtcggg attgaaacaa acttgtgtgt actctctaat ctgataggcc tgcagagtgc
    10561 ttttcctgaa gcagactttt ttgttgatcc aatgttagtc tccagtagaa aacacggaga
    10621 atccgcttta gagctgttga aagatttcaa cgtctctatc gtcgaatcat aaaaatatct
    10681 atcttcattt acgatattta acacacaata aaaaaagcac gcagaactgt tttagtccta
    10741 cgtgcttttt ctatcaaagt agattggctt ttttatgaca cagagtgaaa cggcaggctc
    10801 acgacctctt tcttaaatgg tgttcaatca gctgaccctc ggtattagct taacaaacgg
    10861 caaaatatga ggaactattt ttccgtttgt taagctaata ctcaggtcaa aacgctgatt
    10921 tcacaacctc ttccttaaac ggtattcaaa agcttgcatc tgcagtaata agaacagcca
    10981 agtaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg cagggcagct
    11041 ttttcacaac ctcttatgta ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
    11101 gtctgctcta accaactgag ctaaaggtac atcataaata aaatttattt ttgttacttt
    11161 tcaactatag cacgaatgac aaactctcac aagtttcaaa atataagtaa aataatattg
    11221 ttattcttat ttcttttact tgtgtcataa ctattttgtt actttaattt ttatttgctt
    11281 attttagaaa aaatgttatt cttttattta ttctcaatgt taggagtgat tattttgcca
    11341 tttattgcga ttttattcga tttagttgcg gcagcagctt attttctcca attaaattat
    11401 caaacctcag gaattctgtt tattggaatg atttttcaag gtgtgattac ccttttgctt
    11461 cttgtcatga tgctcagcta taaaggaaaa agatatgccc gtattcaaac aaaagtattt
    11521 gttaaatatg tttccattcg ctatgggatc atcattcttt cctttttagt gaatgcgatc
    11581 gtcctctttt tatatgtatt gaattactta gatatcaatc cattgatttt ttctcgatag
    11641 ataagacaca ttcagcggaa cagttcctgc ttatcagcag aaaactgttc tgctttttca
    11701 tttttcattg atctattctt cttttatttt cctagcattt catttgtgat gtatgcaata
    11761 acatgttatc ttttattata tgaatcgttg aggagtccgt tacatgatta cgttggtgag
    11821 agttttgttt tgggtgcctg cggtcgcact ggtcgcaagt attgtttatc ttatgaattg
    11881 gaacaaagaa cggttttatt tagctatttt gactcttccg gctatctact ttatgtggaa
    11941 agtttttaat tacaactact ttgaacccga tagtgttttt atagaagaat tatcaggact
    12001 ggttttgtct ttattgatcg tcattcttta tttgatacgt ttaaataaaa aacattgagt
    12061 actattgatt gcatgtgtag ctttctatag tcattataac tattctacta taatgaaagg
    12121 tgattaaatg agtatcgaag aagctatttt actggatact ttacgttgtc gtctgaattt
    12181 cttaagaact ggccgatctt tatctcaagt agctgtttct agcgcgttaa gtattccttt
    12241 attcaaatat cgtaagtacg aagaaggaga agaaattcca agcatcattg aattaatcta
    12301 tatcgctgac ttttacgata tttccgttga ttacctaatt ggtcgctcag aaacagcaag
    12361 caaactgaag tgattttttc cagccttggt gctggttttt tcatttaacg tctaaggtta
    12421 acaatctata tataaaggag acatttctat gcgattatgg catgaaaaat tgatttcaaa
    12481 gcttcctcgt caacagcttt taggacaaca tcgggaatgc tgtgcattaa gaggaaatgg
    12541 ctggggaaag aaacatgcta ctgtggatta tgtttttcac tattctcctt atagattatt
    12601 ccaatatcat cagcttgtca tggatgaaat ggaaaaacgt ggttacagcc cagcaccaga
    12661 gtggaaaaat cctatgtatc gtggcaaatc atgcgaagca ttttttgatt tacctactgt
    12721 agagcgcaac gtgccgattt atccggaaca cgatgaagtt tatctagcag aatgtttagc
    12781 aaatttggag caaaaaggaa tttatcttac ctaatataac tagaaaagcc ttctatctcc
    12841 tcttacttca ttaaaaagct ttaaccatct tagatcaagc taaaatgtcg taagttttag
    12901 ggttatcttc atcctcacgt gcaaaactaa aagcgtactc tagttttggt tcatcgccaa
    12961 cttccctaga cataaatgaa catctcctga cgtggtttaa aagtaccgca tcttcgacgt
    13021 ctgtatacga tgcacagcac agattgcttc ttttgatctt tcttttgatt tttctgttgc
    13081 ttcttctaca ccttcttcga ttactacatc gatgcttaca attgcttctg cctaatattc
    13141 ccatgcatcg tcgatttaag cctctgtagt cactgtgatc gtttccacat tttaactcct
    13201 ctgtcgtggc ttcagttgat tttgtgatca gttcagttgc taagccagag tcagaacaac
    13261 ctgccattgc tagcgttaat attgatagta aaaatagttt ttttatcata aggttccccc
    13321 cctgaaaata gactaaaata ataacgcttt ctttttttgt tttcagacga aaattaataa
    13381 tttctaaata ttctttaaaa aagcttataa ctattatgcc ttttttaata tataacacag
    13441 ttatttttaa aaataagaat gctaaatcac tctacaataa cggcgaaagc acaaaaaata
    13501 aaaaaattat tacgttatta aaaaaacaga tgaaagatca ggttttatta gatctcattc
    13561 tttcatcact tgaagggatt taatgaacta ctttttcctc tttgtcgttt ttatatattc
    13621 gtattccttc aaacagtagg atagcctctt tcaatgcttg atatttgaac tgtccgttac
    13681 ttaaaaattt agatgtgccg ccctcttcct agaacatatt cttttttact ttttcattaa
    13741 ttgacagacc aatcgaacga aactgtaaat ttcgatagga taatgattgg tcaaactcat
    13801 tcattttcaa gacatctcga ttcatattca agataggaat ctttttatca acatcacttt
    13861 attcgtattt tcctctacca taaaagcttc acgctccaca aaattgtttt atacactact
    13921 attcagccca ttcaacgacc aatga
//
LOCUS       DAIGTA010000065        13924 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.068, whole genome shotgun sequence.
ACCESSION   DAIGTA010000065 DAIGTA010000000
VERSION     DAIGTA010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.068"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            79..2008
                     /locus_tag="NOB43_002258"
                     /pseudo
     CDS             79..2008
                     /locus_tag="NOB43_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            2134..2688
                     /locus_tag="NOB43_002259"
     CDS             2134..2688
                     /locus_tag="NOB43_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HCI0983094.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQFFVLYAVEYRKMFQRK"
     gene            complement(3418..3732)
                     /locus_tag="NOB43_002260"
     CDS             complement(3418..3732)
                     /locus_tag="NOB43_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HCI0983095.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(3746..4006)
                     /locus_tag="NOB43_002261"
     CDS             complement(3746..4006)
                     /locus_tag="NOB43_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HCI0983096.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            4176..4490
                     /locus_tag="NOB43_002262"
     CDS             4176..4490
                     /locus_tag="NOB43_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0983097.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4492..6147
                     /locus_tag="NOB43_002263"
     CDS             4492..6147
                     /locus_tag="NOB43_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0983098.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            6230..8365
                     /locus_tag="NOB43_002264"
     CDS             6230..8365
                     /locus_tag="NOB43_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0983099.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            8540..9049
                     /locus_tag="NOB43_002265"
     CDS             8540..9049
                     /locus_tag="NOB43_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983100.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            9046..10350
                     /locus_tag="NOB43_002266"
     CDS             9046..10350
                     /locus_tag="NOB43_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0983101.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            10446..11315
                     /locus_tag="NOB43_002267"
     CDS             10446..11315
                     /locus_tag="NOB43_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0983102.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(11427..11747)
                     /locus_tag="NOB43_002268"
     CDS             complement(11427..11747)
                     /locus_tag="NOB43_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCI0983103.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            11850..12296
                     /gene="dhaM"
                     /locus_tag="NOB43_002269"
     CDS             11850..12296
                     /gene="dhaM"
                     /locus_tag="NOB43_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HCI0983104.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            12271..13281
                     /gene="dhaK"
                     /locus_tag="NOB43_002270"
     CDS             12271..13281
                     /gene="dhaK"
                     /locus_tag="NOB43_002270"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HCI0983105.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            13309..13914
                     /gene="dhaL"
                     /locus_tag="NOB43_002271"
     CDS             13309..13914
                     /gene="dhaL"
                     /locus_tag="NOB43_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HCI0983106.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
BASE COUNT         4664 a         2445 c         2956 g         3859 t
ORIGIN      
        1 gctgtgttct atccttttat ttatctctag gcccttattt attttgggac aggtatctct
       61 tcaagaaaag gagagaatat ggacaacgaa atgattagtc aattacaatt tgatcggatc
      121 aaaaaggaaa tccaagcaag agcaattgga aactatagca aaaaacgaat cagcgatatg
      181 acggtctcga caaacctaca aactgtcttg gatcgtcaag aagaaacaag agaagcacgc
      241 ttgatcttag aaagcagtca gcatgttcca tttatggggt tgccgaggat cgatgcactg
      301 acagaacaag tcaaaaaagg gttgattctg cagccaactg atttgatcga atatgcggat
      361 tttcttagaa gcagtcggat gatcacaaag ttttttgata agaatcaata ccagacaccc
      421 ttgttgtttg cttatagcaa acatcttcct gatttgataa atgtagaaga gttgattgac
      481 cagaaaataa aaaataataa agtcagtgac gacgcgtcac gtaatttgcg taaagtacgc
      541 aaacaattac aactaatcga aaaagaaatc cagtcaaaat tactgaaatt cttgcgtcat
      601 ccgaaaaaca aagaaatgat ccaagaagca atgattgttc aaaaaggcga atactatacg
      661 attcctatca aagccagcta taaaaataaa atagatggaa cgattatcga tgaatcaaat
      721 aaaagaacga cggtttttat tgaaccaact gtgatttcta aattgaatga acactatcag
      781 ttgttaaaag ctgaagaaat cagtgaagaa tatcaagtcc tggcggcatt gactggtgct
      841 atcgcagaaa acgaagaagt gatcgattta ttgatcgaaa cgatcacggt gttagatatc
      901 atctttgctc gggcaaaatt tagccgagaa atcaatggaa gcacacctag aatcaataaa
      961 tcggaacata tcattatcaa gcaaggcaga catccatttt tacctgagca tgcggtacca
     1021 ttggatgttg aaatcggtaa agactatcga ggcttgatta tcaccggagc aaatgccgga
     1081 ggcaaaacag tcgtgttgaa gacagtcggt ttattgactt tgatggcgat gttcggtatg
     1141 caagttccgg caaaagaagg gacagagctt gctgtctttg atgagatttt cgtcgatgtc
     1201 ggtgaccacc aaaatttaga aaatgcgttg agtacatttt ctggtcatat gcaaaacatc
     1261 gctgctattt tgaaaaagat aaaaaggaat acgttggtac ttttagatga gattggcagt
     1321 ggaacagagc caaatgaagg ggctgcacta gcgatcgcaa tcatggaatc tatgtatgag
     1381 caaggggcat tgatcattgc cacgacccat tatggagaaa tcaagaaatt cgccggagat
     1441 catgaagatt ttgtgccggc tgctatggct ttcgatcggg aagcacttcg tcctaaatat
     1501 cagttgcggg ttggaagaaa caggagaaag ccaagctttg tggattgctc ataaaatgga
     1561 tatgtcgatg aaattgatcc atcaagcaga gcgttacttg gcggaaaaag cctatcggac
     1621 acagaaaaaa gaatttcttc ctaagacagc agttacaaat aggaaggaga ataaaaaaga
     1681 acgtcagctc tttgcaaaag gtgatcggat atttgtcaat gaataccaaa aagaagcgtt
     1741 agtttatgaa gatataggtg aagatacgat tgatgtatat ttagacaaaa aaataatcca
     1801 cgtgcctcgt cagcgtgttc gtctggtgcg ttcagcagaa gatctgtacc cgacaggtta
     1861 cgatttagac agtctgttta tcgattataa aacacgtaaa cggcagcgtg acctagagcg
     1921 aggatcaaaa aaagctcata aagtactagt aaaagaaatg cgcaaacgac aggaagaaag
     1981 aagagtaaac gatgaaaaca gcaagtgatt atctcaaatt agctcataat atcagtgtct
     2041 gtaaagaaaa ataaaaacag tgaaatcatt ggttttattc cccgtgtaag ctaaaataaa
     2101 aagaaaagag tgctgaggag gtagggcgat aaaatgaaat taagcacaga ctggcgtaaa
     2161 gaaatacaaa cgattccgaa tcttttatcg atattccgta tttttttgct gccgatttat
     2221 ctttattttg tgctgagaca gtcattttat atagcaggag cggtcattgt tgtctcaggt
     2281 ttgtctgatt atctagacgg ggtcattgct cggagatata atcaggtaac agacttaggg
     2341 aaggtgcttg atccgtttgc agataaattg acacaacttt ttctgatttt gtctatggca
     2401 tggtatcgac cgtggctttg gctgttgttt ggtctattct tgataaaaga aggctttatg
     2461 tttgtagctg gattaatcgg gctatctaaa aatatcaaat taagtggagc gaagtggtat
     2521 ggcaaagtag cgactgctgt catctatgtt ggcatgatcc ttttgctgct tttcccagaa
     2581 ttaccaacgc tgtgggtgag agtcattttt gccgtcatca cttacggtct tttacaattt
     2641 tttgtcttgt atgctgtcga gtaccgaaag atgtttcaaa gaaaataaaa aaggggtgtg
     2701 acctatgtcg cattcctttt tttgataaat agactcccag tagctacttc tcgataataa
     2761 gccaaccgaa ccaaaaacag gagaagttgt ttttgaaatt atttcttgtg attcggagtt
     2821 aaatggtagg ctcacaacct cttggtaaac ggtgttcaat cagctgacct tcggtattag
     2881 ctcaaaaaac ggcaaaatat gagcagctat ttttccgttt gtttctctaa tactcaggtc
     2941 aaaccgctga ttttacaacc tcttccttaa acggtattca aaagccagtt tctcggtatt
     3001 aagccaaatt tatgcaaaaa tgtagaaatc cattttcaca aaatttttct taatactcga
     3061 aactaagcga ctttttcaca atctcttcct taaacggtgt tcaatcagct gaccttcggt
     3121 attagctcaa aaaacggcaa aatatgagga gctattttcc cgtttttttc tctaatactt
     3181 aggtcaaacc gctgatttca caacctcttc cttaaacggt gttcaaaagc ttgcatctgc
     3241 ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc tgttcttatt
     3301 acttgatgca ggacagcgtt ttcacaacct ttgattcacg gttttccaga agtagcttct
     3361 tcgaaaaata agccgaaatt tcttgaagct gatcacttct gtcgcaacct ctactgacta
     3421 aggcttgata taagcataac cttgggattg cagttcaact aaatcaagga cacctgctgg
     3481 tacaacgatt acttgttcag gtaaagaact ttctgaaata tgattagcac gcatagcatt
     3541 ggcgcaagcg tgaaaaacga ctccttgcaa atctaagaat tctgcattgg cagagtctag
     3601 ataaccggta atcgcgatgc catttacaga tacgacaatc gtcgtttctg gagaagcttt
     3661 tatcaggttt tttacgtttt tccctgtttc tgaccatttt tctaattcat caatatggaa
     3721 aacgactttc attgaaatca ttcctttact ttttaataat catcttgatc gcttgttcta
     3781 gtttagccgc ttgttcttct ggattactat caggtttctc aaagcaattt ttcagattat
     3841 ctgcaacgat catgcccatt acgcgatcaa tactagaacg aacagcgctt aattgagtga
     3901 tgacatccat acattctttt tcgtcttcga tcattttttg gataccacga atttgtccct
     3961 ctgtacgttt caaacggttc aggatatttt tattatcaat ctccataaca cattctcctc
     4021 tatttttata attagataat accccttatc ggtattttat gcaaatataa aaagtagtga
     4081 aaaaaatgaa gagtcattct ggttgacata ttaataaagc tcctgtttaa tataccccat
     4141 gaggtattta taaaaatgta aatgaggtgc agaaaatgaa tttgctattt caatcaataa
     4201 aatcgataac agtcccagaa ttaaaggaaa agcttttgga aaatccagcg ttacttgatg
     4261 ttagaacacc tgcagaatac cggggcgggc atataaaagg agctaaaaat gttccattac
     4321 aaagtataaa cagatatgat ggagacaaag aaaagaccgt ctatgtgatt tgtcaatcag
     4381 ggatgaggag taaacaagca gctaaagaat taaagaaatc tggttatgat gtagtgaatg
     4441 tacgtggtgg catgaatcaa tggtttgatc gaacagtagg agggaaataa gatgaaaatc
     4501 gttattgtcg gaggtgtagc aggtggaatg tctgctgcta cacggcttcg ccgattaatg
     4561 gaagatgcag aaatcgttgt ttttgaaaaa ggaccgtatg tttcttttgc aaattgcggc
     4621 ttgccttatt atctttcggg agaaatcagt gaacgggaaa atcttcttgt ccaaacgcca
     4681 gaatcattat ccgctcgttt ttgtttagat gtgcgtccaa atcatgaagt gacagccatc
     4741 tttcccgaaa acaaaacggt agaagtcgta catgagggtc aaaaacacat tgaacagtac
     4801 gatgcattgg ttttatctcc tggtgcaaaa ccagttgttc catcgattcc agggataaca
     4861 gaagccgaca atgttttttc tattagaaat gtaccagata tcgataaagt gatgcatgca
     4921 ttagaaaaac agccaaagcg tgccgtgatc gttggtgcag gattcatcgg attggaaatg
     4981 gcagaaaacc taaaaagaag aggtttagaa gtcatggtga tcgaacaagc accacatatt
     5041 cttccaacac tggatgaaga aatggcagct tttatagaaa aagaattgtc tcatcaagga
     5101 gtagaagtga ttacttctca tgctgtcgct ggatttgaag accacgggaa acgattgcga
     5161 ctggatgatg ggcgtaccat ccctgctgat ttagttattt tatccattgg tgttcgtcct
     5221 gataaccagc tagcagtgac cgctggaatc gaattaggca tacgcggggg tatcctagta
     5281 gacgaacgtt atcaaacgaa tattcctgat atttatgcgg tgggggatgc tatcgttgta
     5341 aaacagcaaa tcactggaaa agatgcactt atttctcttg cttcaccagc caatcgtcaa
     5401 ggtagacaag ttgcggacac gatttccgga atttctcgaa gaaatcaagg cggtattgga
     5461 acagcaatta tacgaacgtt tggaatgact gccgcatcca ccggtttaag tgaaagaaca
     5521 gccaaagaaa acgaactgtc ttttgaagtc attcatgtat caggaaaaga tcatgcaagc
     5581 tattatccag aagcaacaga tattttactg aagttgatct tccatccaga gactggcgag
     5641 atttatggtg cacaaggtgt tggggcaaaa ggtgtggata aacggatcga tattttagca
     5701 acagcaatca aagggcattt gacgatcttc gatttaccgg aattagaatt gacgtatgca
     5761 ccgccatttg gctcagccaa agatccagta aacatgctag gatatgcagc aatgaacatt
     5821 gcagaagggc ttagtgaaac cgtacaatgg catgaattgc cgacagaact agcaaaagga
     5881 aaaattttat tagatgtgcg aacagcagaa gaattggaaa agggcaaatt caaggaagcc
     5941 aaacatatcc ctttgaatga acttcgggac cgattaaatg aattagacag ccaacaagaa
     6001 tatatcgtca gctgtcatag cggattacgt agctatctag cggaaagaat cttgaagcag
     6061 tctggctacc acgtaaaaaa ccttgatggt gcattttctt tatatcaaac tgtccgacct
     6121 gaagaactga tatatcctaa caaatgatac tcgttaaaaa gcttgcattc gactcttaaa
     6181 agaggtaaac taatcggttc caccacttta aaaaaagagg agaatgtgta tggtcaacac
     6241 acaaaaacag ttagaagaag catatctgaa gaacgtgtat caaaagctaa ttgataaaaa
     6301 aaacgaactg cgggaatcga tggatacggc aaaaatagaa ggaaaccagt cgttgaaaga
     6361 aatggctggc gagcttcgat tgaattttga cagttactta gataacctgg atactttttc
     6421 gatgattgaa atgaaaaata gagaaatcga tcagatgaat atcaaacaga aaaacgcaga
     6481 aaatcagcta gcaaagatcg aacgtttatt gaaaagtccc tactttggaa aagtcgttgt
     6541 agactttctg gataatgagc caaaagaatc cttttatatc ggtacagcaa atttcacaga
     6601 tgatgcagat gaaaatcttg tttatgattg gcgttcacca attgccgaac ttttttacaa
     6661 taacatgatt ggtccatctt cttatacggt tcgtcaaaat aaaatcgata cggttattaa
     6721 agaaagacga caatttcttt tggaaagaga tcgtttggtc aagttttttg atacgtctgt
     6781 agctattcaa gatgacgtat tattagaagt cttaggccaa gatgagacca atgaaatgaa
     6841 ggctatcact gctacgatcc aatcggaaca aaacacaatc attcgggatg tgaaaagtca
     6901 aaatatcttg gtaaatggcg tagcaggaag tggtaaaacc tctgctatca tgcagcgtat
     6961 tgcgtatctg ctctatttat atcgagatac gatgacatcc gatgacttgc tgattctatc
     7021 acctaatcat cggtttatcg actatatttc gaatgtccta ccatcattag gtgaaagaaa
     7081 tccactgaat ctaaccatca tacagctggt ttcacagctt tcagcagagg aaatagaagg
     7141 tgaagaggct tatttcaaac gtatcacggg agaaaatgta tcggagcaga cagaacgttt
     7201 gcgtagcaaa aagtttatcg ataatctaaa acaatcagat cctttgtttt tagatcatcc
     7261 gaattttatc cgtggactta ctaaaaatgg aaaaacagtc ctttctaaaa aaacgatcga
     7321 aaaaatatat gagaaagttc ctgctcatcc taaattgatc gataggcttc aagcaacgaa
     7381 aaaggcactg atgagcgaat ggaagaatca tcttttgaaa caagcaaaaa gtcctgctgt
     7441 gcagaatcag gtactctcgt tgacagaaga taggcagttg gaattattcg gtaaattgat
     7501 ttctgatgat tcggaacaaa gtattgtagc ttatgcaagg aaacttttac aaaaaaaata
     7561 tcgaaaaata accagacaaa tcgaagaaat ggcatgggtg gatgagcatc agttgtttga
     7621 aagaatttat gaaaaacgat atggctcagc ttatgcttgg caacccacac gtactgttga
     7681 tgaagcagtc attatattag ctattcgtca tttacttgtt gaaaaggtaa atgtaccagc
     7741 atttcgctat ctattgattg atgaagtaca agattatacc ctggcacaat taggtctatt
     7801 gatcgaatta tttccaaaaa ctcactttac tttagtaggt gacgagaatc aggcaatctt
     7861 taattcttcc actacttttg ctgatattat gcgttgtttc gacgactacc atctgccgat
     7921 ccatcggtat gatcttagaa atagttaccg ttctagcgga gcaatcacag agcttttcaa
     7981 aacctatgct gtggatcaag agaagatcga catcgtatcg atccgaccgc aaggaaaaga
     8041 acccgaatac cgctcttttc gatcctctga agaattgttg aaaatactag ctgagatttt
     8101 ggtttctcta aaaggagaaa aagcggcagt tatcacccaa acagaagagg aaacccaaac
     8161 gctacaagaa tcgattaaaa aaaattcata tggattagaa aactgccaaa tcattccttt
     8221 gagtctagca aaaggactgg aatttgatca tgtaatctta tatccatttg aaaacgatgg
     8281 agatgagcaa agaagacgca gacaaatgta cacggcgata tctagaggaa tgaaaagcat
     8341 tgtcgtattg gaaagagcaa cataattaag agataaaaaa taaaaagaac aactgataaa
     8401 aagaacaaaa tatttttcat ttgctgatga gaaatgtttt gttctttttc ttaggaaaaa
     8461 tttaggaaca ctttatgtga aaagaaatga aatgtatggt aaactcctac gtcgtaacaa
     8521 aaaaacgtga ggtgaggata tgaaaaaagt aacaagagaa gaagttgcat caattttggt
     8581 gaaagataag tatttttcaa aaggtaatta ctggttaaag atttggcaaa cgttagtggc
     8641 tcttttagga tggatgatcg ttgttcttcc ttttatatgg gtctttttcc cattaacgag
     8701 accagaaaga gccaaggatt tttccttgta cgctttttta tcagaaaaga aaatgctgta
     8761 tttcttaatc ggcttttttg tattgatttt tttcagtttc ctgattacct catttgtatt
     8821 gactaggtgg aacaatcgaa atctatacaa aaaagtaaat aaatcttttg aatatgaaga
     8881 tgaaaaattg aaaaaaagac aagaattact tgaagaagtg tatacggaac gttttggaac
     8941 aaaagaagag agagaaacgg tccgttttta ttctgtctcc gaagagaaaa atctagatac
     9001 gacattcatt gcagatttgt ataaagaaaa tggggtggaa ctgaaatgat ctcaatcacc
     9061 catacaggta atttattctt agatacttgt ttgtctatta tgtatttttt tctcgtttct
     9121 tatccgattt taggcggatt tgtatggttt attggtgtct ggtgttatgt gtttttatac
     9181 aaacataagc aaaaagaatg ggtagatgtt cccttgagtg tcgaaccgtt catcacgatc
     9241 atggtgccag cccataatga agaaattgtg atcgaatata caatcgagta tttgatgacg
     9301 aaattgaatt atcacaacta tgaggtatta gtgacagacg atggttcaac ggaccaaaca
     9361 ccagaaatat tagctagact gatgaaaaaa tacgctaatc ttcgtgtggt tcggatcgaa
     9421 aaaaataaag gaaaagccca cgcgtttaat atcggacttg cctttgcaaa agggaaattg
     9481 attttaagca atgatgcaga cacggtaccg gagccagatg cactgattag gtatgtgaat
     9541 tatttcattc gccctggtgc aagacatatt gctgcggtca ctgcaaatat ggatgtccaa
     9601 aatcgtacca aattgattgc aaaatctcaa acggttgaat tctcaagtat cgtgggcatc
     9661 attaaacgaa cacagtcagc tgttttcggt ggtctttatg cgtacagtgg agcaaatacg
     9721 atgtatcgaa aagaagcctt gatcgatgtg ggcggattca gacaagatcg agcgacagaa
     9781 gacatcagta ttgcttggga tcatcagtta aatgactggt tatctgtttt tgctcctgag
     9841 attatctttt tcatggaagt acctgtgacg ttgaagatgc tatatcgaca cagaaaacgt
     9901 tgggcaaaag gtggaacaga agtctggctg acgaatttca aaaaagtgat gctccatcct
     9961 tttaaacata ttggaagaac gatcatcttc attgatcaaa cattgagtat tgtctggtca
    10021 atattctttt gtatttccgt agttcttttt gctggattaa tcgggcatta tgtatatcaa
    10081 ggaaactacg aacagattta tattactttt acattcagtt ttgtgttcat ctgctttgaa
    10141 atggtcgcag gatttttcca gttgctagct tcgctgattg tagatgatcg acgaagaaaa
    10201 ttgaaatacc ttcttttcgc accactatat atgcttttgt tctggatagt gaacgcgata
    10261 acgatcgtga cgactttcat tccagcagtc aaaacgattt taggttatgg aagcgggaca
    10321 tggaaaagcc cggaacgtac aaaaaaataa aagatgcacc gttttttaga caaacagcct
    10381 gttgtgttta tggttcttcc aaacattttt gcttataata agaaattagt taaaaagtag
    10441 taaggatggg aaaagtgatg aaaaaaagaa tgaagccgtt aatctggcca attgctgttt
    10501 ccagtatttt cttattggga cagacagctt ttgcggaaac ttctgaacct gctcaaacag
    10561 aaccttcaac aaccataagc tcttctggtg ctgaaaacgg tgcctcggaa acagaaatga
    10621 cttccaatgt accgacagat aattcaggag aaacgatttc atcttcagaa gatacatcaa
    10681 taaatagttc tacctcttct gaccaaatcg atcatttgca agacttggaa aataaaagaa
    10741 aagaactcga agaagcatta gaagctgcaa aaaacaaatt gaaagaagac caagcagcaa
    10801 tcgatcaaga tttagctgat cttaaaaata aagtgggaaa tgaccgtgca caacttgaga
    10861 aaaagcttgc cgaagcgaaa gcaaaagcgg aagctgtcca aacagatctt gacgggaaga
    10921 tccaacaagc aaaagaattc aatcagcaat taaatcaggt tgctcaaaca gcttctggaa
    10981 agctaagtca aactcaagcg gatatcacag cggccagtca agcaatccac ggaaagatca
    11041 gcgaagcaca aacagttgct aatgattttg aagcaaaaaa agctgactta gcagctagtt
    11101 tccaacgaat aaaagatatt ttgcattcgg caggagaaaa atcagtgacc tctggaagca
    11161 cgacagaaac agttcagcaa acgacagagc catccaaatc aacaagtcag actttgccaa
    11221 aaacaaatga aaaaacagct tctgtcagtt attccttagc aggggcgggt gtgttagtcg
    11281 cagcagctta cggaatcatc cgcaaaaaga aataaaaaag agaggatggg aaggtagagt
    11341 acctcgaagt tagactgaaa aatctaattc ttgagtgcca ctacatgtcc catctctctt
    11401 tagttattaa aacagatgtc ccctacttat ctcgtggaga cagctgttcc actacatgtg
    11461 accatcagca tgccattgtc gctgcctaat acttcatagt ccatttttac gccaatgatc
    11521 gcatcagctc ctaatgcttt tgcacgttcg gccatttcgg caagtgcttc ttctcttgca
    11581 cccattagtt cgttttcata gctttttgag cggccgccaa agatatttcg caaccccgcc
    11641 tccaagtctt taaatgcatg gatcccagta atgacctcac caaaaacgat ccctttataa
    11701 gctactacgg cttttccctc tacactgttc gttgttgttg taatcattcg atcactcctc
    11761 tcttttaatt aaagtataac aaacttcaag aagcactaca catattttcc caaaattaga
    11821 aatttattat atacttgaat tgttcattaa tgaaagcgaa accaatcgtt agcaactatg
    11881 taaaagaaag gaagattctt gtgaaaaaaa gtattttgct tatttctcat agtcaaaaag
    11941 taacagatgg tattaaagaa atgattgagc agatgcaaaa atccgaagag gtgcaaattt
    12001 tttctctcgg cggaataaat ggcgagatcg gatcagaccc gatgaaaatc gtagaagcag
    12061 tcaatgaatc aagcgatgca gctagttatt ttgtttttgc ggatatcggt agcgcggtat
    12121 tgaactcgga actggcaaaa gacatgttgg aagaagagca gcagcaacgt tatcatctgg
    12181 tggatgcgcc tttagtggaa ggagcttttg cagcagccat cactgccggt ataacagatg
    12241 atactcagca aatcttaaca gaagcacaaa atgccggaaa gaaaggatgg gaataaattg
    12301 aaaaaaatca tgaatgatcc aagcaatatt gtcgaagaaa tgctggaagg attagtaaaa
    12361 agctatccag aacttgttca tcgtgtagaa tcttcccgtg ttgtagccaa gaatcagaaa
    12421 gcggaacaag ttggtttggt ttctggtgga ggaagcggac atgaaccatc ccatgccggg
    12481 tttgtagggg aagggatgtt aagtgcagcg gtgcttggtg atgtgtttac ttctccaact
    12541 ccagatcaga ttcagacggc tattaaggaa gccgatagtg gaaaaggagt tttgctgatc
    12601 gttaagaatt atacagggga tgcattgaac ttcgatatgg caaaggaatt agctgctatg
    12661 gacgatattg aagtagaaag tgtgatcgta gatgatgata tcgccgttga aaatagtacg
    12721 tatactgctg gaaaacgcgg agttgcaggt actgtccttg tacacaaaat cgtgggcgat
    12781 gcagcaagaa acggtgcttc cctagctgag ttgaaagaac tgggagaaaa ggtcgtacag
    12841 gcaactaaga cgatcggtct agcgcttcga gcagcaactg taccagaagt agggaaacca
    12901 ggattcgaac taggagaaga tgagatcgag tatggtgttg gtatccacgg tgagccaggc
    12961 tatcgtcgag aaaagatgca gccttctaaa gtactggcaa aggaacttgt tactaagatt
    13021 ttagatgatt actcgaattt accaaaagaa gcaggtgtac tagtcaacgg aatgggcggg
    13081 acgcctttga tggaacagtt cgtgttcatg aatgatgttt tagctctgtt ggaagaaaga
    13141 ggcgtcaatg tagttttccg aaaagtcggt aattttatga cctcactaga tatgcaaggt
    13201 ctttctctaa cactgatcga cttgacggag acacaatgga aagattcttt agaaagcaat
    13261 gtacagacga tttcatggta aaaaatctca agataaaagg gtgataatat gaaactaacc
    13321 gttcaagaaa tccaagaatg gctcacgcaa tttgcagagg caatcaatca gaacaaacaa
    13381 tatctcagtg atctagatac cccgattggc gatggagacc atggaaataa catgggaaga
    13441 ggggtttcag cttatgaaga agcttttcaa gccgatcatc ctgaaacaat cagcgataca
    13501 ttcaaagtat tctctatggc gatgatatcg aaagtcggtg gggcttctgg tccgttatac
    13561 ggatctgcat tcatgaacat gatgaaagcg acaaaagagg tcgattctat tgattctcaa
    13621 gaaaaattag gcgaagtgat cgagcaggga acagcgggta ttcaaagccg aggaaaggca
    13681 gaagctgacg ataaaacgat gttagatgtt tggctgccag tcacagaggc attgaaggca
    13741 gggaatttaa caaaagaaat cattgaccag gcaaaagaac acaccaaagt cttggtagct
    13801 aaaaaaggac gagcttccta tctaggagag cgtgcaatcg gacatatcga cccaggagct
    13861 gcttctagtg ccattttatt ttcaacgctt ttagatgtga tcaatcaacc ttaagttcaa
    13921 taaa
//
LOCUS       DAIGTA010000066        13852 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.069, whole genome shotgun sequence.
ACCESSION   DAIGTA010000066 DAIGTA010000000
VERSION     DAIGTA010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.069"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..903)
                     /locus_tag="NOB43_002272"
     CDS             complement(<1..903)
                     /locus_tag="NOB43_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HCI0983107.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSES"
     regulatory      complement(927..971)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1186..2154
                     /locus_tag="NOB43_002273"
     CDS             1186..2154
                     /locus_tag="NOB43_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0983108.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2267..2545
                     /locus_tag="NOB43_002274"
     CDS             2267..2545
                     /locus_tag="NOB43_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI0983109.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2663..2899
                     /gene="secG"
                     /locus_tag="NOB43_002275"
     CDS             2663..2899
                     /gene="secG"
                     /locus_tag="NOB43_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCI0983110.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3002..3757
                     /locus_tag="NOB43_002276"
     CDS             3002..3757
                     /locus_tag="NOB43_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0983111.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3760..6117
                     /gene="rnr"
                     /locus_tag="NOB43_002277"
     CDS             3760..6117
                     /gene="rnr"
                     /locus_tag="NOB43_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCI0983112.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6139..6603
                     /gene="smpB"
                     /locus_tag="NOB43_002278"
     CDS             6139..6603
                     /gene="smpB"
                     /locus_tag="NOB43_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCI0983113.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6905..7624
                     /gene="atpB"
                     /locus_tag="NOB43_002279"
     CDS             6905..7624
                     /gene="atpB"
                     /locus_tag="NOB43_002279"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCI0983114.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7677..7892
                     /gene="atpE"
                     /locus_tag="NOB43_002280"
     CDS             7677..7892
                     /gene="atpE"
                     /locus_tag="NOB43_002280"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HCI0983115.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7983..8507
                     /gene="atpF"
                     /locus_tag="NOB43_002281"
     CDS             7983..8507
                     /gene="atpF"
                     /locus_tag="NOB43_002281"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCI0983116.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8494..9036
                     /locus_tag="NOB43_002282"
     CDS             8494..9036
                     /locus_tag="NOB43_002282"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCI0983117.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9059..10615
                     /locus_tag="NOB43_002283"
     CDS             9059..10615
                     /locus_tag="NOB43_002283"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCI0983118.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10629..11531
                     /locus_tag="NOB43_002284"
     CDS             10629..11531
                     /locus_tag="NOB43_002284"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCI0983119.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11554..12960
                     /gene="atpD"
                     /locus_tag="NOB43_002285"
     CDS             11554..12960
                     /gene="atpD"
                     /locus_tag="NOB43_002285"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCI0983120.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12974..13396
                     /locus_tag="NOB43_002286"
     CDS             12974..13396
                     /locus_tag="NOB43_002286"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCI0983121.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4576 a         2474 c         3013 g         3789 t
ORIGIN      
        1 actttcggaa aaaagacgag tatctacttt tgtcataatt ttactgttag caggtttctg
       61 ccaaaattca taacgatcaa ccaatgtttg tccacgactt attccctgag tttccacagc
      121 ggtgaagctt ttgaaacctt cacagatggc cccctcgatg aaataagcaa cagctaacgg
      181 atcattgatg acacatccta aaattctttc ttgtttccag tggaagtcaa aataaaaacg
      241 agtgatcgct tttaaatact ctccctcttc aggattcatt tgacagcagt attcgaggat
      301 agtcggtgtc aagacgattt ctcttgtcac atctaaccca accatttcta tcgtttgttt
      361 gagattctcg aatacataag aagctgcttc aggatcacac cagtaattgt attcagcaac
      421 tggcgaacag ttaccatggc ttttgtaagt tccacccatc gagacaaaac gatccatatg
      481 tttcccaata tttgggttga ctttcaaagc aaaagcgata ttggtcaaag gacccaaagc
      541 aatgactgat gtatttgtct tttctttgaa ataatcagcc aaaaaatcaa cggcatggag
      601 aggttctgcc tgttttctca agatcatcgg gaaatttgtt tcccctaaac catccatacc
      661 atgagtgtct tgtgcactga tgaaaggttg cttcaaaggt ttttccattc cttgataaac
      721 aggaatgtct aaacgatcac agcgttccag gcatttcagc acattctgcg tacctatatc
      781 tgcagggaca ttcccacaaa ctacggtaat agcaactact tcgatatcag gggatttgac
      841 agctaatgat aaagctaaag tgtcgtcgat ccctggatcg caatcaataa ttacttttcg
      901 cattatttcc aatctccttt ctttagagat acttagtttt ttattctggg aagtttccga
      961 accagtccaa gacgagcgtc ttgattataa tgcacgaaat tagtatactg gcttttattg
     1021 cgaatgtaaa tgctctctta caagtaaatc tattgaggag aactttaagt aaatgataca
     1081 atgaaaaaga aatggaattt acgtgtgccg aaaataaaga atcctatgga tcggtacatt
     1141 ggataataga tagattatag tttggcagaa agcggcgggt gtacaatggt tattttttat
     1201 ttcattctta ttctgataat tatagggatc agttaccatt ttctttctta tttttatgca
     1261 aagaaattag taagagcggg agtacagaga ggatatgact ggtatgaaga cactggtcat
     1321 cgtttgatgg accctgctgc agtcacgtca gtagaaaaaa aacgacaaaa attagaagaa
     1381 gagtgtgaaa gcttttggga gcagggaaca cccaaaacaa tcaaaagtta tgacgggttg
     1441 aaactagctg gtcagatgtt catccatcca aataagcaga ataaatgggt catttgcgta
     1501 catgattacc gaagcacagg gaaaagagac atgtctcata taggtaaaag atatgcagag
     1561 aaaggattca acgttcttgt acctgattta cgtgcgcacg gagaaagtga aggagaaatc
     1621 atcggaatgg gatggctaga tcggctagat ttaattgcct ggatccaact catcttagat
     1681 gaacagccga atgcgtccat tattttacac ggcggatcaa tgggagcttc tacgatcatg
     1741 atggcaagtg gtgaaaaact tccatcagcg gtcaaaggat ttattttaga cagcggatat
     1801 gtttctgttt atgcagaatt ccgatatatg ttaagtaaaa tcactgtctt tcctaaaaaa
     1861 atggtcatga gatatgcgaa tcattatgcc cagaaatacg ccggttactc cttaaagcaa
     1921 gcatcagcta cgagacagct tggcagcaac catctgcctt tattagtcat ccatggtgaa
     1981 agagatcatt ttgtccctac agaagcagcg tacacgattc aaaatgctac ggcaggggat
     2041 aaagcactgc tgcttgttcc agaagcagaa cacttggaag catcgatgaa agatccgaaa
     2101 acctattgga cagtgatttt ttcatttatt gaacaaagaa taacgatgga ttaattttct
     2161 cttctttttt gtaagtaatt cgaggataaa taattgttta tagatctgga gactgctaaa
     2221 ataaggtagg aataaaaaaa tatcagttat ttgaggagtg cggcatatgg aaatcaaaga
     2281 agaaaaaaat cgtcttgctt tattcaatga tgagcaacaa gagattggag aaatgacatg
     2341 gtcagatgcg ggcccagaca tcatgatcat tgaccataca tttgtagatc cagcatatcg
     2401 tggtcaaaag ttagctgaaa agctagtgta tactggagta gaattagcaa gacgagacgg
     2461 gaaaaagatc attcctttat gcccttatgc aaaaaaagag tttgaaaaga aaccagaata
     2521 tcaagacgtc ttacgtcagt cataagaata acagctgaaa gttttgaact ttcagctgtt
     2581 attccattta tatagagttg tcacggactt ttatctatga taaagttaaa gagacgatat
     2641 cttttgggaa ggaggctgcg atatgtataa tttaattttg ggaatcgtga tcgttttatc
     2701 gattgttatg gtcattgcga ttatgatgca gccaagcaag caaaatagtg cagcgagtgc
     2761 atttaccggc ggtgcggatc aactattcgg caaacaaaaa gctcgcggct ttgaagctgt
     2821 catgcagcga tcaactgcag ttatgggagc tatctggatg atcttattat ttgtcctagc
     2881 atatttatct tcgaagtagt tgaataagcc tctcgcaaaa cggcgggcgg ctttttttat
     2941 tgcaaagaga acgcttaaga agaagttatg aaagaaacta tggtaaaatg aggcgaaaga
     3001 ggtgagacga gtgagacaat taccaaaacc cctttatgca aaacatggaa agcgagcggt
     3061 tttgctgctt cacgcttact caggaagtcc aaacgatgtt cgaatgctcg cacgattttt
     3121 ggaaaaagca gattatacag tttatgcgcc gctttttaaa ggacacggaa caatggagcc
     3181 atatgatatc ttgcaagaaa aagcagaaag ctggtgggca gacactaaaa aagccatcca
     3241 ttttttacag tctgagcagt tttctgatat tgccgtatta ggattatcaa tgggcggcat
     3301 ctttgctgta cgagcactag aagaagaatc agtgattggc ggcggttttt tctgttcgcc
     3361 tttgtctcct gtaaaaacaa acgtgcctga aaactttgaa aaatacgtac gtcaagtgct
     3421 gaagacagca ggtaaatcag agaaagaaat caatgaaaaa gcagttgctt accgctcgtt
     3481 agctgaacaa caattaatgg atatacaaga tcaggcagca atcgtagaaa gtaggttgtc
     3541 agatatccaa cagccgatat ttttagctca agctgggaaa gatgaaatga tcgaccctaa
     3601 tggcgtattt gaaactgcac gcaagttgag ccgtcagcga gtgacacttc aatggtatcc
     3661 tgaaagtggt catgtgatta cagttggtac agcaagacgc gaattagaaa aagacgtctt
     3721 ggaattttta gaaaaattac cttggaatga ggaataaata tgacaaaaga aacgataaaa
     3781 gagaaaattc tctttttcat ggaaagcagt cgcaaacgca gtttttctat ggaagaaatc
     3841 gctgaaggtt tagggttcca aaaaagcgat gattttaaat tactagtaca aacgattgct
     3901 caaatggaaa gagaacagag tatagttttc aataaaaaag gaaaagtgaa acttccttta
     3961 aaaccaatct tgatcgaagg aacatttcga gcaaatgaac gaggatttgg atttgtaacg
     4021 attgatcccg aagaagatga catctatatc ccaaaagaag cgactggttt tgcaatggat
     4081 ggagacaccg tagcaatcga tatcatgaag cgagcaaata cagatatgga tcgcggagca
     4141 gaggggaaag tagtcgagat tcgagaccgg gcgactactc agttagcagg ggaattcgtt
     4201 gcttattcag aagaagaaat acaagaaaca gatctttacg gcgttgttat cccgaaagat
     4261 agaaagctca accaatttaa agtatatgca gcagcagagg gagttcgtcc agttgacgga
     4321 agtattgtgc tgatcgaact gacccattac cctgaaaaag ggtatgcgac tagtttagaa
     4381 gggataatca agcaagtgat tggtcataag aatgaccctg gcatggatat cctctcaatt
     4441 gtcgtggcta atggtatccc tacgaaattt cctgatgatg tattgtctga agcagatgaa
     4501 gttccagatc aaatcagcga aaaggatata actggacgta gagatttaag aaatcagctc
     4561 attgttacga ttgatggaga agatgcaaaa gatctagatg atgcagttac ggttaaaaaa
     4621 ttagataacg gtaattattt tcttggagta cacattgcag atgtttctta ctatgtgaca
     4681 caaggcagtc aattggacag agaagcatat gaaagaggga caagtgtata tttgactgat
     4741 cgagtgattc cgatgatccc gcaacgttta tcgaatggta tctgttcact gaatccccat
     4801 gttccaaggc tgaccatgag ttgcgaaatg gagattgatc caaatggaca agtagtctct
     4861 catgatattt tcccaagtgt gatccaaaca acagaacgga tgacctacac agctgtcaat
     4921 caaatcttag aagatcaaga cgaagaaacg atgcaacgct atgctcagct cgtacctatg
     4981 ttccaagaaa tgggtgaatt gcatcgaatc cttgaaacga tgcgaatcaa acgtggcgcg
     5041 atttcttttg aggatcgcga agcgaaaatc cttgttgatg ctgaaggaca cccaaatgac
     5101 atccagctaa gaagcagagg aattggtgaa cgcttgatcg aatctttcat gcttgcggcc
     5161 aatgaaacgg tagctgaaca ttataataaa ttaaatctgc cgtttattta ccgaatccat
     5221 gaacagccaa aagaagaaaa aatgcagcgc ttctttgatt ttgcttcagc tttgggcatt
     5281 ctggtccgag gaacgaaagg aacgatcaca ccaaaagatt tacagcatgt gatcgaagga
     5341 gtagaagaca aaccagaagc tgcagttatc aatactatgt tgctaagaag catgcaacaa
     5401 gcacgctatt cagaagacaa ttttgggcat tatggcttag cggcagatta ctacacacac
     5461 tttacatctc ctattcgacg ctatcccgat ctaatcgtcc atcgtctgat ccgttcttac
     5521 agtgaagata aaagtgaaag caatcaaagt tcgtgggctg cggaacttcc tgaaattgca
     5581 gatcatagtt ctaagatgga acgtcgtgca gtagaaacag aacgtgaagt agattccatg
     5641 aagaaagcag aattcatgat ggacaaagtg ggagaagaat tcgatgggat catcagctct
     5701 gttgtgaaat tcggcctgtt tatcgaactg ccgaatacag tagaaggatt gatccatatc
     5761 aatgaattga aacaggacta cttccatttt gttgaaaatc atttagctct tgtaggtgaa
     5821 agaactggtc tgacttttaa aatcggacaa aaagtgcgcg taaaagtagt caaagctgat
     5881 ccagatgaac gagcagtgga ttttgaactc gtttccgcag aagaggtcac tgcgttggaa
     5941 cgtccaaaag cacgcaatgg aaaatttgga aaacgagaag gaaaacaagc aggcaaacgc
     6001 tcagaaaaaa atggcaagaa gaacaaacga tatagtgata gtaagcaaac gttcggtaag
     6061 aaaaaaggga aaaagccatt ttacaaagat gtcaaaaaga agaaaaagaa aaaataaaat
     6121 gagttggagg aaacagctat gccaaaaggc gagggaaaac taattgcaca aaacaagaaa
     6181 gctcgccatg attattcgat catcgacacg atggaagcag ggatggtctt gcaaggaacg
     6241 gagatcaagt cgatacgaaa cagccggatc aatctgaaag atggatttat tcgcgtccgc
     6301 aacggggaag ctttcttgca taatgttcat atcagtcctt atgaacaagg aaatattttt
     6361 aatcatgatc cgttgcgcac gagaaagtta ttattacaca agaaacaaat cgttcgtctt
     6421 gaaaacgaat tgaaaaacac tggaatcact gttgttcctt taaaagtcta tattcgtaac
     6481 ggctatgcca aggtattgat tggtctggca aaagggaaaa aatcgtatga taaacgggaa
     6541 gatttgaaac gaaaagatat cgatcgacaa attgatcgaa cattaaaaaa tttctctaga
     6601 taatttcatt atcctttttc gcatattcgg tgcttttgct tttacttaat gataaaattt
     6661 gttagcattt aatctgataa aacatgatta tcacaggttt tttcttagat caggagcacc
     6721 gtgcatgggg aaaaattcgc ttcgtttttg actgaaataa aaaagtgtct aattttcatg
     6781 aaaatgtttt gaattttctg tttcatggtg gtatgatacc gtgtggttag aaaccgattg
     6841 gaaaaaacca gatacgcaca tgaattgatt ttatgtgaat ttcggggaaa agaggtgaaa
     6901 tggattggat gaacgctcgc taacgtttca cattggacca atttggtttg atggtacagt
     6961 ttgtataatg gtgttactga cctgtttgat tgttttcttc ttagcttact tttttacaag
     7021 aaatcttaag ttgaaaccaa caggcaaaca aaatgcgata gaatgggtca ttgattttag
     7081 tcgaggaatc gtaacagata atctgcctag aaaagaattg agcaatttcc atttgttggc
     7141 atttacattg tttttatttg tttttgttgc aaacaacata ggtttagtaa caaaaatcgt
     7201 cttacctaac gaaacaacac tttggaaaag cccgacagca gacccgtttg ttactttaac
     7261 tttggcattt ataatgatct tacttactca cttattcggg gtgaaaaagt taggcttcaa
     7321 aggatatttc gtaaattcgt tcttgaaacc ctatagtttt atgtttccga tgaaactgat
     7381 tgaagaattt acaaatttat taacacttgc tttacgtctt tatgggaata tttatgcggg
     7441 ggaagttttg ctaaccttga ttgcaaaaat gatgacaagc ttaggctggt tctcattacc
     7501 attagcaatt ccattagaga tggtctggat cgcgttctcc ttgtttattg ggagcatcca
     7561 agcatttgtc tttgtcactt tgtcaatggt ttatatgagc cataagattg aagtagaaga
     7621 ataatactcg gttaaaaaac aaactactat ttatctattt taggaggaaa acaattatga
     7681 attatatcgc agcagcaatc gcaatcatgg gagcagcaat cggagccggt tatggtaacg
     7741 gtcaagttat ctctaaaaca atcgaatcaa tggctcgcca acctgaaatg tctggtcaat
     7801 tccgtacaac aatgtttatc ggggtagctc tagttgaagc tgttcctatc ttaggggtag
     7861 ttatcgcctt gattctagtt tttgccgttt aattgaatca gtattaaggc agaaacaaca
     7921 tcgtttgtta ctgctttttt acatggaaac tagaaatact ccaaagaaag gaaggctcgc
     7981 ctatgctgaa tcaattggca attgcagaag ttggcaatgc gatgttaggt aatatcatcg
     8041 ttgtcagcgg ctcatttttg atactactgg ctctcttgaa gcactttgct tggggaccaa
     8101 tcagcgatat tttgaaaaaa cgtgaagaca agatcgccaa tgatttagat tctgcagaac
     8161 aatctcgcat caactcagcg aaaatggaac aagaacgcga acaacaattg ttagcctctc
     8221 gttctgatgc agctgatatc atcaaaaatg cgaaagaaag tggagaatta agccgccaaa
     8281 atattttgaa ggatgctcaa gaagaagcag ctcgtctaaa aagcaaagcc caagctgata
     8341 tcactgtaga acgtgattca gcgctgaact ctgtaaaaga cgacgttgca gaactctctc
     8401 ttcaaatcgc ggaaaaaatc ttgaacaaag aattatctcc agaaatgcat gaatcattaa
     8461 tcaatcaata cattgaaggt ctaggttctt caaatgaaac tagataaata tacagtagga
     8521 agacgttacg ggaaagcttt atttgaactg gcgatcgatt caaatcaagc agaagaaatc
     8581 tatcaagatc tcgtaagttt acgtcaaatc tatgaacaag tacctggatt agggaatatg
     8641 ttaagtgatg ttcgtctaga acctcatgaa aaacgagaaa tcatggacaa gcttgtcagc
     8701 ggttatgatg ggatcgttaa aaacttttta gaagttgttt atgagtataa ccgaatggat
     8761 gaccttttgt tcatgatcga agaatatgaa cgtcgatatg atgaacatca agggttacta
     8821 ttgggaagtg tcacaacagc agtcccactt tcagacgaac aacgaataca attagaaaag
     8881 aatgttgcaa aaacaatgga ctatcaatca gttgaattaa aacaaatcgt tgattcttct
     8941 attattggtg gcgcgattgt tgaagccaac catcgagtaa tcgacggaag cattcgcacg
     9001 caattagaaa aaatgcgtaa tcaattaaac agatagtaca aagaggtagg tgaatcgaat
     9061 ggccatcaaa gcagaagaaa ttagtgcctt gattaaagaa caaattgaaa attatcaaaa
     9121 cgtgctttca gtcgaagaaa tcggtaccgt aacttatgta ggtgacggga tcgctcgtgc
     9181 acatggttta gaaaacgcga tgagtggtga gttgcttgaa ttttcaaacg gctcatacgg
     9241 aatggcgcaa aacttagagt caaatgatgt aggtatcatt atccttggcg atttcgagtc
     9301 cattcgtgaa ggagataaag taaaacgaac aggtaagatc atggaagttc cagttggaga
     9361 ggccttgatc ggtcgggtag tcaatccgct aggtcaacca atcgacggac taggtgaaat
     9421 cgttactgac aaagctcgtc cagtagaagc gatggcacca ggtgttatgc aacgtaaatc
     9481 tgttaacgaa ccaatgcaaa cagggctaaa agcgatcgac gcccttgtgc caatcggacg
     9541 cggacaacgt gaattagtca tcggtgaccg taaaacaggg aaaacttcta ttgcgatcga
     9601 tacgatcatc aaccaaaaag gtcaagatat gatctgtatc tatgtagcaa tcggacaaaa
     9661 agattctaca gttcgtacac aagttgaaac attgaaaaaa tatggcgcaa tggattacac
     9721 aatcgttgtg aatgccggtg cgtctcaacc agcaccattg ctttatatcg caccatatgc
     9781 tggtactgca atgggtgaag aattcatgta caacggtaaa catgtattga tcatttttga
     9841 tgatctttca aaacaagctg ttgcttatcg tgaactttcc ttgctgcttc gccgtccacc
     9901 aggtcgtgaa gcttatccag gggatgtttt ctacttacac tcacgcttat tggaacgtgc
     9961 agcaaaatta agtgatgatt taggtggcgg ttcaatgact gccttaccat ttgttgaaac
    10021 acaagctgga gatatctctg cttatatccc aacaaacgtt atttcgatca ctgatggaca
    10081 aatcttctta gaaagcgact tgttctacgc aggtactcgt ccagcggttg atgccggact
    10141 atctgtatct cgtgtagggg gttctgcgca aatcaaagca atgaaaaaag ttgctgggac
    10201 tttacgtcta gacttagcaa gttaccgtga attagaagca tttacacaat tcggttctga
    10261 cttggatgca gcaacacaag caaaactaaa tcgtggacgc cgtacagtag aaatcttgaa
    10321 acaaaaattg catgcaccgc tagctgttga aaaacaagta gtgattttgt atgctttgac
    10381 acatggattc ttagatagta tccctgtaga cagtatttta gacttcgaac atgaattatt
    10441 cgaatatctg gataccaatc attcagatat ctttgaaaca atccgtacaa caaaagatct
    10501 tccagaagaa gaagcgttga acagtgcgat tcaggaatat aaagacatgt tcttagctac
    10561 aaaaggaaat aattcctcta cagaagataa attgaaatcc attcaaaatg catagtgagg
    10621 tgagatgaat gggtgcttca ttaaatgaaa tcaagacacg tatcgcttca acgaaaaaaa
    10681 cgagccaaat cacgcgggca atgcagatgg tgtctgcttc taagttgaca aaatctgaag
    10741 cttcttcaca gaagtttcag gtttatgcaa caaaagtaag agaaatcgtt acgcatttga
    10801 ctgctactca gttaaatgat attgcctcag aaaatcctag aggggatatc aattacaaca
    10861 gcatgttgct cagccgtcct gttaagaaaa cgggttatat cgtcatcact gcagatggcg
    10921 gtttagtcgg tggatataac agctcgatat tgaaacaaac gatgtctatt ttagaagaag
    10981 accaccaatc acccgatgat tacgtgatga tcgcaattgg cggaactggt gcagacttct
    11041 ttaaagcacg cggtatcaat ctagcatatg agctgcgcaa tctatctgat cagccaagct
    11101 ttgatgaagt ccgcaaaatc gtaaatatgg caacaactat gtaccaaaac gaagtattcg
    11161 atgaattata cgtatgttat aaccatcata tcaattcgct aactagtcag tttcgtgtag
    11221 aaaaaatgct gccaatctca gacttagatc cagaagaagc aactactttc gaacaagaat
    11281 atatttttga accttcaaaa gaagaaatct tgtctcagtt attgcctcag tatgctgaaa
    11341 gtttgatcta cggtgcgatc gttgacgcca aaacagcaga acatgctgct ggtatgacag
    11401 caatgaaaac agcaactgat aatgctgcta atatcattga tgagctgacg gtttcttaca
    11461 accgtgcaag acaaggggct attacccaag aaattaccga aattgttgcc ggagcttcgg
    11521 cactagaata gtattgagat tggaggaaaa aagatgagtt caggcaagat tgttcaagta
    11581 atcggtcccg ttgtcgacgt ggaattttct ttagaccaat ccttaccaga tatcaacaac
    11641 gcattagttg tttataaaaa tgacgaaaat aaatcaaaag ttgttcttga agcagcgtta
    11701 gaattagggg acggagtgat ccggaccatt gcgatggaat caacagatgg tttacaaaga
    11761 ggaatggaag tcattgatac aggcaaagca atctctgttc ctgtaggtaa agaaacatta
    11821 ggtcgcgtat tcaacgtact aggagatacg atcgatttag aaacaccttt cccagaagat
    11881 gcggaaagaa gcgaaattca taaaaaagca ccagcctttg acgaattaag tacaagtaca
    11941 gaaattttgg aaacagggat caaagttatc gatttgcttg ccccatattt aaaaggtggg
    12001 aaagtcggac tattcggtgg tgccggtgtt ggtaaaaccg tactgatcca agaactgatc
    12061 cataatatcg cccaagaaca tggtggtatt tctgtattta ccggtgtagg tgaacgtact
    12121 cgtgaaggta atgacttgta ttatgaaatg aaagattcag gagttatcga aaaaacagcc
    12181 atggtgttcg gacaaatgaa cgaaccacca ggtgcacgta tgcgtgttgc tttgactggt
    12241 ttgacgattg cggaatattt ccgtgatgta gaaggtcaag atgtactgtt gtttatcgac
    12301 aacattttcc gtttcactca agctggatct gaagtatcag ccttgttagg acggatgcct
    12361 tctgcggttg gttatcaacc aacattggca acagaaatgg gtcaattgca agaacgtatc
    12421 acatctacga aaaaaggttc gatcacatcg atccaagcaa tctatgtgcc agccgatgac
    12481 tacactgacc cggcgccggc aacagcattc gcccatttgg atgcgacaac caacttggaa
    12541 cgtaaattaa cagaacaagg gatttatcca gcggtagatc cattggcttc ttcttcaagt
    12601 gctttagcac ctgaaatcgt gggagaagaa cattataaag tagcaacaga agtccaacac
    12661 gtattgcaac gatatcgtga attacaagat atcattgcta tcttaggtat ggatgaatta
    12721 tccgatcaag aaaaagtgtt agtttctcgt gcccgcagag tccaattctt cttgtcacaa
    12781 aactttaacg tggctgaaca atttactggt cttccaggtt catatgtccc tgtagaagaa
    12841 acagtgaaag gattccgcga aatcttggaa ggcaaatacg atgatcttcc tgaagaagct
    12901 ttccgaagtg ttggccgaat cgaagacgtc gtagaaaaag cgaaaacact aggctactag
    12961 aaaggggtgc cccatggatc aatatttaac agtaaatgtg gtaactcctg ccggtttggt
    13021 ctatgatcac catgcagcta tcgtcgttgc acgtacgaca gctggtgagc ttgggatttt
    13081 gcctaaacat gcaccaatca tcgttccatt gacgattgat gaagttcgtg taaaacgaac
    13141 agattcagat acccacgtcg attggatcgc tgttaatggc ggaatcatgg aagttcgtga
    13201 taatgttgtt tcaatcgttg ctgatagtgc ggaacgtgaa cgtgatatcg atgtatctcg
    13261 tgcggaacgt gcaaaacaac gcgcagaacg ccaaatcgaa gaagcaaaag caaaacaaga
    13321 tacgaacgaa ttgaaacggg caactgttgc gttgcaccga gcaatcaatc gtatcaaagt
    13381 atctaagcac tcataaaatg agatgcggat gtttatccgt gtttaagaac agtaaaaaga
    13441 ggttatgaca gaagtggtca gcttcaagac ataagaagga atttacgaaa attgcttctc
    13501 aaatttttgt gaaatctcag cttatttttc gaagaagcta cttctggaac accgtatatc
    13561 ggaggttgtg aaatcagcgt tttgtcctga gtattagaga aacaaatgga aaatagttcc
    13621 tcatattttg ccgttttttg agctaatacc gagggtcaga tgattgaaca ccgtttattt
    13681 ggaataaggg actgcgacaa gacttttgtg gctctttgtc aataaggact gatgagttgt
    13741 gcaaaatcaa atctgagtca gaatgaacca cattctggct cagatttttt gttatcttac
    13801 attgattaat tgattgatca aaaagattct aattctcatg ttctcaaatg at
//
LOCUS       DAIGTA010000067        13399 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.070, whole genome shotgun sequence.
ACCESSION   DAIGTA010000067 DAIGTA010000000
VERSION     DAIGTA010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.070"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(59..601)
                     /locus_tag="NOB43_002287"
     CDS             complement(59..601)
                     /locus_tag="NOB43_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HCI0983122.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            736..1125
                     /locus_tag="NOB43_002288"
     CDS             736..1125
                     /locus_tag="NOB43_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983123.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1129..1893
                     /locus_tag="NOB43_002289"
     CDS             1129..1893
                     /locus_tag="NOB43_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0983124.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2022..2969
                     /locus_tag="NOB43_002290"
     CDS             2022..2969
                     /locus_tag="NOB43_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0983125.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3099..3839
                     /locus_tag="NOB43_002291"
     CDS             3099..3839
                     /locus_tag="NOB43_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983126.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4130..4798)
                     /locus_tag="NOB43_002292"
     CDS             complement(4130..4798)
                     /locus_tag="NOB43_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0983127.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            4932..5219
                     /locus_tag="NOB43_002293"
     CDS             4932..5219
                     /locus_tag="NOB43_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983128.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            5635..7173
                     /locus_tag="NOB43_002294"
     CDS             5635..7173
                     /locus_tag="NOB43_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HCI0983129.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7170..8135
                     /locus_tag="NOB43_002295"
     CDS             7170..8135
                     /locus_tag="NOB43_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983130.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8122..9444
                     /locus_tag="NOB43_002296"
     CDS             8122..9444
                     /locus_tag="NOB43_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0983131.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      9507..9611
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9685..10428
                     /locus_tag="NOB43_002297"
     CDS             9685..10428
                     /locus_tag="NOB43_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983132.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            10443..11435
                     /locus_tag="NOB43_002298"
     CDS             10443..11435
                     /locus_tag="NOB43_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0983133.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            11447..12184
                     /locus_tag="NOB43_002299"
     CDS             11447..12184
                     /locus_tag="NOB43_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983134.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12174..12896
                     /locus_tag="NOB43_002300"
     CDS             12174..12896
                     /locus_tag="NOB43_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI0983135.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(12980..>13399)
                     /locus_tag="NOB43_002301"
     CDS             complement(12980..>13399)
                     /locus_tag="NOB43_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCI0983136.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         4412 a         2295 c         2786 g         3906 t
ORIGIN      
        1 aaaactgtct aacatttaaa atttaattta gatattagac agtttttaag tttgtgagtt
       61 attttccttg tcgttttctc acttttttag tccagaaacc acctgaaata tattttggct
      121 cataagaaat gataaaagca cgctcttcga tttctttgat caggcgatac agttcacgtt
      181 cgctttttct aggagaaagt atttcgagaa ctagccgctc accttccagc cccattgcag
      241 aagtctgtgt cacaccataa ccgtgttctc tcagtatacc cggcaaactt ttatcttctg
      301 cgctatttgc tggcaaaatc gttgtgacca tgatgtatcc taatgccaat ttgtcttcaa
      361 tcaaaattcc gacactgata cctactgcgt aacctaacgc atagacaaat aaattcagtg
      421 gattatctaa acgatctaaa acaagggata agccgacgat ataaatcgtg atctcgacca
      481 tactgacaag tggagcaatc agtcgatagc ctttcattgt caacatgaaa cgtaacgtgt
      541 tcagagtgat ataagcaaaa ttaatgagga agatcatccc caacattttt ggatcaatca
      601 tttgtaaaac tcctttcatt tatataacaa caatatcaaa aaaaatcgta agtgaagaaa
      661 aattgaaact ttatacatac aaaaaaatga taaaatgatt ataatagaat tataaagata
      721 ggttaggtga ttaaaatgaa aacggtcaat cgtgtgtttt gtgccagcca cgtgctaagt
      781 ctccttctca gtatatactt aggtgtctat tcgattcaac agccaattga ggtagagaac
      841 attgtttttc agatgtcgct gacagatggt ttaattttaa gcgttttttt ctttttgata
      901 ctgtttattg gtaatatttt cggtagcgtt gccagttttt tgaatttttc tatttatcca
      961 ctcctttcgc tagcattagg agtggtggga ctttgttctc tgtgcttatt tcccgagcca
     1021 ttcagtcctg catttatatt atttggtaca ctgaacctgt tccagacaac tgttggagca
     1081 tggttgctat ggcgatcagg aaatttaatg aaaataggtg agtaacaatt gaatccaatt
     1141 atattgaaac gttctgtcca tcatattcca gtgttagaag ttgttctgaa agaattaaga
     1201 gaggaacgta ttcccgttgt catctattat cacggatggc agacaagtaa ggagttagtt
     1261 ttgacgcaag gaagaaaaat tgcgcagcag ggcattcgtg tgatcctgcc agatgcgatg
     1321 aatcatgggg agcgcaaaca gccggtttct tctattccat cctatacatt ttgggatagt
     1381 atctacggaa atctgtttga atttgacaca cttatcaagc atttagaaaa aagaggtctt
     1441 ctacatgatc agcttgcagt tggcggggtt tcgatggggg gaatgacaac atgcgccttg
     1501 ttggctaaac atcctcatat agtagcgggc gtgtgtttga tgggttcccc tgcacctttg
     1561 gaatatggaa aagaaatcgt aaggcgcgca tcggaatata attatgtcgt accaaaagac
     1621 tattttgatt tgatttcatg ggttaagagc tatgatttgt cattgcagcc ggaaaagtta
     1681 gctggacgtc ctctgttctt ttggcatgga caagctgacg aaaaaatccc ttatatacaa
     1741 acggaacgat ttgtagaaaa aaatcggcat aagtcttacg gaaaagaaat tgtttttcgt
     1801 tcctcaaaaa cacagcgaca tatggtacaa ataccactaa tggaagaagc ttccactttt
     1861 ttagcaaaaa atttgataaa aaagtataaa taattgaaac ggaaaatcac tcatgacgat
     1921 agaggatttt ccgtttttta ttttgggcta taataaactc tgttaggaaa atttggtata
     1981 attgatagta agaatgacaa catgttagaa aggaagagag catgcccact ttagcagatg
     2041 ttgcaaaacg tgccaatgtt tcaaaaatga cggtctctcg agtcatcaat catccggaac
     2101 aggtgactga cgaattgaaa gagttagttt tctcagcaat ggctgaactg gattaccgtc
     2161 caaatattgc tgcaaaagca cttgtcacga atcggtcgca gatcatcaaa ttatttatac
     2221 tggaagaaat cgacacaact gagccctatt acatgaattt gctgatggga atcgctaaac
     2281 ggatcggtaa agcgcattat tctctccaat tagttacaaa tgatgccttc gacgtcggtt
     2341 cttgtgatgg atacatcatc acaggtgtca gaaaaaaaga cttcgattgg atcgaccgtt
     2401 tggaaaaacc agttgtcttg tttggggaaa attctgaagg atatgattat gtagacagcg
     2461 ataatgaata tggtacagca aaagcaacgc aatatgcctt agaaagagat tatcaaacga
     2521 ttatttatat cggtatcgaa gtggacgagc cttttgaaat ttcaagggaa actggttatt
     2581 tatctgtgat gaaggaagtt gatcttccta gtaaaatctt gcggtttcca aatcattcga
     2641 cagaagtaga aagatatatg acagaaaact gggcagattt tacagataaa acttgttttg
     2701 tatgtagttc agatcggcta gcactaggag cagtaagagg gattataaat gctggaggac
     2761 acttgcccga agaatttggt gtgattggat ttgatggggt atttttagac caaatcagtt
     2821 cacctaaatt gacaacgatc aagcaagata ttatacgtat gggtgaagta tgtggagaaa
     2881 tgttgttaaa aaaaatagaa gaaaaagggg cgagtcaagg ttatcgtcgt ttttttcctg
     2941 aactagttat cagagagaca acgaattaag tcttattact atatatatat ttatgaaatt
     3001 catcgctatt ttcttaaaat aatcagcgca ttgctactga aaacaatgaa tctgtgctat
     3061 tattgagaaa agttccattt ttgagaagga tggtttgaat gaaagaaatc agacgaaaac
     3121 atttccgttt tcctgcgtac gatgatgagt taggcgtaaa attaaccaac gacaagaagc
     3181 gagtattatt tgacggacaa gaagatcttt tgactgaaca gaatcagtcc ccgtttgaac
     3241 agatgaaaga atttcatttc acgaacacga acaccgagaa aatccgtcgc aagcgtcgtg
     3301 caacaaatgg attgaagtca gctccgcgta aggaaaattt ggaaaagcat aaaggaaaat
     3361 taccggatta taccggccat taccaatcag aaatcacatc gacaggacga aaaaaacttt
     3421 ttggtgattc ctctcgttct gtcagacaaa gtgaaacaag gacagagtcc aagcatacta
     3481 cacgaaacgc atctgttgac acgaaggtgc gggagcgttc ttattttgtt cctaaatatg
     3541 tacccgcatc gattatccca gaccctagag aaagcaaaat ttctgaggat catttaatcg
     3601 aatcgatgaa aaaaacggat gactcttatc tgttgttcga tacagaaccg acgccgtatc
     3661 aagaaaaaag aaatggtgag ccgtctgtac gaacattcaa tcgaacaaaa acgttagagg
     3721 aaacaaagca gtcagaagaa aaaaaatcga aaaaaagcca tggtatctta gaacgctcat
     3781 tacaaggatt gatcgatgat caaggaaact ctttgggaga aaatagctat tttaaataag
     3841 tgatatacaa atttatattc ggctacagtt ggaaaggaaa cgctgcggcg tttccttatt
     3901 ttatactcta tccgaaagtt tatatcgtat cctcaaattt ttttgagttt aagcgaattt
     3961 tttctcccaa taagtaagaa aataatggca aaataaaaaa acaaactatt ttcgcagatc
     4021 gtttgcaaaa atagtttatt tttttataaa gaagatttta ctgaataata tcattttagt
     4081 ttacataatg atatttctgt aaattaaata aagtagtgaa aaataagaat cagtgctcta
     4141 actgttcaag aggatcaagt ggttcaaatg tttctgtagt ctgttttgct tccaattggg
     4201 gcaaaacaga tccaatttcc agatacttca ctttattcaa tgtataagat agaatagaac
     4261 agctaagtaa tgtatacaga aaatgtgtga gatccaaata aagcaaggag acaactaaaa
     4321 taccaaaagt aatcaagaaa agacttttgc caatcttaat atgaaaatat ttttcaatgg
     4381 cttgataaat gatatctgtt ccgcctgtgc ttccgccgaa tcgaaagacg agaccgcaac
     4441 caatgccaga aagaatacct gtcatcaaac tattgatcag tagactatct acagcaaaat
     4501 gtatatgaag gctctcccat aaatgtaaaa agaaaactag cgcaaatgtt ccgacgatcg
     4561 tccggagaaa agcgtgtttt ccaaaaagaa acaatgagat aagcaataaa ggtaaattaa
     4621 aaagcagtga agtgacagaa ggagcgaatc caaaaagatt atgcaaaagc aaagcaatac
     4681 cagtaacccc accatctgcc agcttagatg gaatattgat tcctgtcaca gctaatccgt
     4741 agattcctgc gcctaaaatg attccgcaca attctgtaaa taaatttaat tttttcattt
     4801 ctagcctctt ttcttttgaa aattttcagc aacttcttta ttatactgac ttatactctt
     4861 acttcaagag gaaaatgaaa aaaaattatt tttggctgtt tctttttatt tatcaaataa
     4921 ggagtggaaa aatgcgagca gcagacttat tgacaattct tacaaaatca cccaaaaaaa
     4981 cagagtatca aggagttttt ttggctcaag aacaaaaact ggtgcctgtg acaatggtcc
     5041 agataaataa agcaaatcaa tttatctttt tatttgaaca cggcaaagca ccacttgcta
     5101 tgaaagacat ctttcttttt ttgatgaaga accgtgagaa agctgtttat tatcagtcaa
     5161 aagaagaact cattcctctt tatggagtga aagagataga aaataaagtg gtgatataag
     5221 taaaaataag aaaacaagac gtttatgatg tcaaaacaac cattttttac atttttggca
     5281 aaaaagtgtc atgatacagt ataatattcg ttgaacaggc caataaaggt gttctccccc
     5341 acgagatttc tactttattg gctgtttctt tttattaaaa taaaagttgt gtgtgtaaaa
     5401 aagatatagc tgattccaag tgacaatttc gtatagattt ttatggtatt cgtagtgaaa
     5461 aaacgagaac caaaaagttg atccgacttt gttgcttgga ttcttttttt gtcagcatat
     5521 ttagaggtat ttttttcttt tttttgttcg tgctgtaagg ttaaggcaag acaagttagt
     5581 tgggaaaaag gaaagaaatg tttatactta aagaataaca gaaaggaagg tcgcatgaat
     5641 aattttatac aaacattaag tgaaagaaaa ggcgagttgc tggaagctgc atttcaacat
     5701 ctgtccattt ctctcatttc tttgctgatt gcagcactga ttgctattcc tttagcgatt
     5761 tgggcagcca atcataaaaa aatggcagaa gtcttattgc agatcacggg tgtgctccaa
     5821 acgattcctt cacttgcctt attaggttta cttatcccat ttgtagggat cggaactgtt
     5881 ccagcattga ttgcacttgt tatttacgct ttgcttccga ttttccaaaa cacgtatatt
     5941 ggtctagctg aaattgaccc gtctattgaa gaagcagcgg tagcatttgg tatgtccaga
     6001 atgagacgct tgctgaaagt agagcttccc atcgcattac ctgtcattat ctcaggtatc
     6061 cgaactgcct tagttttaat catcggtacg gctactttgg cagcattgat cggagcaggt
     6121 ggattaggga catttatttt gttaggtatt gaccgaaata cacctgtttt gacattgatt
     6181 ggtgcgatca gttctgcctt gcttgcaatt atattcagcg gactgattcg ctggttgcag
     6241 cataagaaac ctcgatattc catcattact ttagcagcag tggtgtgttt atttggcggc
     6301 gtttctttat atcagtctgc cttgtttaaa aatgaaacca tcacgattgc tggaaaatta
     6361 ggagcggaac ctgaaatcct gatccaaatg tataaagaat tgattgaaga caacacaaaa
     6421 acagaagttg aattaaaacc gaattttggc aagacgagtt ttttgttcaa tgcactggat
     6481 caaggtcaaa tcgatatcta tcctgagttc acaggtactg tcctagaaag cttggtgaag
     6541 gtacctgaag caatgaaaag tgctgatttg acaaaagaaa aaacatatga cgaagcagaa
     6601 gaattattga ataagcaatt cgatatgaca ttattaaaac caatggctta ccaaaatacg
     6661 tatgccttgg cagtcaagag atcttttgcg aacgaacatc aacttaaaaa gatttccgat
     6721 ttggcagcta tctctgatca gatcaaagcg ggattcacac tggaatttat tgatcgttca
     6781 gatggatata aaggaatcca agaagcatat ggcttgaatt tttcaagtgt acaaagcatg
     6841 gagccaagtt tgcgttacca agcaatcaat aatggagatg tcaatattgt ggatgcctat
     6901 tccacagata gccagctcaa ggagtacgat ctagtgactc tagaagatga tcgagggtta
     6961 ttcccagctt atcaaggcgc accgctgatg aaaaaagatt ttgctaaaga acatcctgaa
     7021 atcgttaaag cactgaataa attaagcgga aaaataacag aggatcaaat gattgatatg
     7081 aattaccaag tcaatgtcga aaagaaaaag ccgacagaag tagcacgaat cttcctgaaa
     7141 aatgaaggat tagtaaagga ggaagatcag tgactaaatt aatcgagttc aaacatgtgc
     7201 aaaaaaagta tgatggaaag tatgtcatcg atgacctaaa tctggcaatc aaaaaaggag
     7261 aaatctttgt tttggttggt ccttccggta gtggaaaaac aactactttg aaaatgatca
     7321 atggattatc taaaccatca gcaggagaca tctacttcaa aggaaaatcg ttaaatgaat
     7381 ataatctgca gaaaatgcgg tggaatatgg gatatgtgct gcagcaaatc gctttgttcc
     7441 cgaccatgac agtcaagcaa aatattgaag tcatccctga aatgttaggt tgggaaaagc
     7501 agaaaagagc agaccgtgta gatgaacttc ttcaaaaagt tggcttatct cctgatattt
     7561 atcgagatcg tatgcctaga gagttgtctg gaggagaaca gcaacggatc gggatcatcc
     7621 gagctattgc tgcaagccca gatgtgattt tgatggacga gccatttagc gcattagatc
     7681 cgatttcaag aaactcatta caagaattgg ttttgtcctt acacgaagaa ttgggcacga
     7741 ccatcgtttt cgttacgcac aatatggaag aagcaatcaa gctaggtgat cgtattgcat
     7801 ttatgaagga tggagaaatt atccaatgtg acacaccaga gcagttattg atgaatccta
     7861 aaaacgacta cgttcggcat ttctttgatg aaccgaaaca gacgaaagag tggcgagtag
     7921 aagatttagt cgtcaatgga tatttcttaa atgaaatacc agaaaatgct cgtcaacaag
     7981 tttgctttga tacgcctatg aaagaagtat attcgcttct ttcggtgtat ccaagcattg
     8041 tgatagtaga aaagcaaaga agtattgggt cgctgacaag taaagaaatc tttgcttttt
     8101 taagtcgaga ggaggaagga aatgaaaaca tatgatgcaa tcatcatcgg ttcaggtgtg
     8161 agcggcttaa gtgctgctta tggattgaaa gaagcaggta aaacagtact agtggtcgaa
     8221 gaagatctat ggggcgggac ttgtcctaac cgtggatgtg atcctaaaaa agtcttgtta
     8281 agtgcagtag aggcacgtaa tcgggtaaaa caattgagtg gaaaaggttt taacgagatc
     8341 ccaactgcca actgggaaga acttcaaaaa ttcaaacgaa catttacgga tccagtccca
     8401 gaaagccgaa aaaaacaatt agcagaagct gaaatcgatc atctttcagg aaccgctcgt
     8461 tttttggatg attcatctat tgaagtcaac gaagaagtct tccatgcgga ttacttagtt
     8521 ttggcaaccg ggcaaagacc tacgatctta ccagtggagg gaaaggaata cttgaaaact
     8581 agtgcagact ttttatcatt gcctgtactg cctaaagaaa tcatttttat cggtggtggt
     8641 tatattgctt ttgagctagc tacgattgcc aatgctgcag ggagcaaagt aaccattgtc
     8701 catcataatc aacggccatt aaaagaattt gaggcgtctt tggtagagga agccgtccat
     8761 caaatggaag catctggcat tcagtttgct tttggtgttg aaacccaaaa gatcatttca
     8821 gaaggtactc gctatcgttt agtcggaaaa gagacggaat tagtagcaga tatgattttt
     8881 tgtgcgactg ggagacagcc gaatacagaa tctttagcac ttgagcaagc gaatatcgtc
     8941 tttgataaac acggaattgc agtcaatgat tatctgcaaa cgagcaatcc aaaaattttt
     9001 gcgtgtggag atattgtttc aaggaaaacc ccaaaattga caccagtcgc cacttttgaa
     9061 ggaaattatg tagctaagcg gataacggat gcaacaagcg aacctatcaa atatccgatt
     9121 atacctacga tcgtctacgc cagtcctaaa cttgctgaag taggagttac aaaaagtcac
     9181 gcctcttcgt cagatcaagt ggtagagatg gatcttacca gttggttcac ctatcatcgt
     9241 gtcaatgaac cagttgctaa ggctgaattg acctttgacc agcaaaatta tttgattggt
     9301 gctgcagtga ttagcgagca agcagacgaa ttgatcgatg atttgacact cgtcatcaat
     9361 caaaaattga ctaaaaaaga gttggatagc tatatcatgg ggtatccgac attggcaagt
     9421 gatctctcct atttattgaa ataatcagca tgataactaa agcgcttgtt gctttttcct
     9481 tcttgtgcta cactttaaaa aatgaatacc tgtttctggg gatgtcgtag acgacatgag
     9541 agtaagttgt gaacttagac ccattgaacc tgtcagttaa tactggtgaa gggagaaaca
     9601 tagcagacgc ttgaagcggg ttactatgtc gtgcccattt caagcgtttt ttgttattca
     9661 tattagaaga aaggaggtaa caaaatgaag aaaaatcttt atccagcagt cagtatggca
     9721 ttcattttaa ttatttggca gattgttgtc atagtttgga aaatacctgc ctttatttta
     9781 cccggacctg ctgctgtatt ttctgcatta gcggcagatg cacaagtatt actttcccat
     9841 tctgtcacga cattaaatga agcagtgctt ggtttggtaa tagctagcgt tctttctttt
     9901 attactgcct tggcaatgga ttattggaag tttttagaaa tgtcttttta tccgttacta
     9961 gtgatttcac aaatgttgcc aatcatggtg ttagggccat tacttaccct atggtttggt
    10021 ttcggtatgc ttccaaaagt gatccttgtt gtcttgataa gctattttcc gatcgtagtt
    10081 tctttttcgg atacattgag gaaagtatca aaagagcaaa tcatcttttt gaaaacgatg
    10141 ggggcagata cagggaagat ttatcgaata tataaaatac cagcgggttt atccggcttc
    10201 ttttccggtt taaaagtggc tgctacttat tgtgtcagcg gagcagtcgt tggagaatgg
    10261 ctaagcgctc aagcaggctt agggtattac atgatacgcg taaaaaacag ctaccagatc
    10321 gataaagttt ttgctgcgat catttgtgtc attctattga gtttattgct gaatggcgct
    10381 tgttcattat tgaaaaaagg gtattatcgt atgctttata ttttttaaga gaaggggatc
    10441 aaatgaaaaa attatggctt ttattaccgc tactgttgct tttatccgct tgtggcactg
    10501 caaaagaaac aagtagcaaa caagaaataa aggatttgaa aaaagtgaca cttgttttgg
    10561 attatgtacc gaatactaat catactggca tctacctagc aaaagaaaaa ggctattata
    10621 aagaggctgg tttaaatgtc caaatcatcg aaccaggaga taattcgaca agtattggtc
    10681 tagtaggtgc ggacaaagca caatttggtg taagttatca agaagatgtc acttatgctc
    10741 acgcagatgg acagaatata ccagtcaaag caattgctac agtgatcaaa cataatactt
    10801 ctggattcgc caccctatca gacagtaaca tccattcacc aaaagatttt gaaggaaaaa
    10861 catatgcagg ttggcaaagt ccaagtgaag aagctgtctt aaaagctgtg atggaaaaag
    10921 acggcgggga cttttcaaaa ctgacaatgg taggaagcaa tggagaaggg ccagaaagct
    10981 taggaaaatc ctcagatatc caatggtact ttgaaggttg ggatatgatc aaagcaaaag
    11041 aagcgggtat tgaactaaac tatatcccat tgaaagaatt agatgaacgg ttagattact
    11101 atactccggt aattattacg aatgatcaac tgatcaaaag tgatccagaa ttggtacagt
    11161 cttttatgga tgccacgaaa aaaggctatc aggaagctat taaggatcca aatgacagtg
    11221 ctaaactgtt gcaaaaatat gcaaaagaaa atgatcggac gtttttagaa gaatcacaag
    11281 cattcttgtc aaaaaattat acggatgatc ctgagaattg gggattgatg gaagaaaaag
    11341 tttggcgcaa ttatacagct tttatgcagg aaaacggatt gatcaagcaa gatgtacctt
    11401 cgcaagaact attcactaat cagtttataa aataggagtg atagatatgt caatccaaat
    11461 cagccacttg aatgtagtca ttgaaaacct gaaaatatta gaagacatcc atttcactat
    11521 ccctaaagat acctttacat cgattgtcgc gccaagcgga gccggtaagt caacattgct
    11581 gaaaacttta acaggagtcc agcctatgac ttctggaacg atcaaagtag acgatcaaaa
    11641 agtaactggt ctccatacag catttagtta tatgccgcaa gaagatatgt tacttccttg
    11701 gctgagcgtc tatcaaaacg ttacgttata tcaaaaaatc aatcatctaa caatcaatga
    11761 agaacaagta agggattatc tggatatctt tgggttaaac ggctacgaac attttttgcc
    11821 ggaacaatta tctggcggga tgaagcagcg aacggccttg ttacgaacaa tcatgaatcc
    11881 ttcttcttac ttgcttcttg atgaaccatt tggagcgtta gatgctatga ccagagggca
    11941 gatgcaagac tggatgttga agctgcctaa aaaagcaaag cggactactt tacttgtgac
    12001 gcatgatatc gaagaagcaa tttatttatc agacaggatt cttgtgcttt ccgcccgtcc
    12061 ggcacatgtg attgctgaga ttcaagtgcc tgaaaaacga cggtcacgtg aatggctact
    12121 gcagcaatca gagttgaagc aaacgattta tcagttattg gcaggtgaat tagatgttaa
    12181 gtgatgctca ttgtcattta gatgggagtc agagtttagc actccttcag caggaacaca
    12241 cgattttgac gatcatcaat tgtgattcgc cagaagaatg gaaggaaaac agacagcttg
    12301 cagcaagtaa gactcaagcc ttaagttacg gtatccatcc ttggaaagca gatagctata
    12361 cgtttgaaca agttgagcct tttttgaaaa aagcaaggat catcggtgaa atagggttag
    12421 ataatatttg gacgaatgta ccgatgacta cacaaaaaaa agtatttgag cgacagcttg
    12481 cttttgcagc cataaatgag aaacctgttg tactgcacac aaaaggatgc gaaaaagaga
    12541 tcttaaatta tatccaagct taccctaatc actatttgat ccattggtat tcttctttgg
    12601 actatcaaca agactatatt gatttaggct gttatttcag cattggtctt gatttgaaaa
    12661 agaatccagc agtctggcaa ctagctaaag cagtcccaat cgaccactta cttattgaaa
    12721 cggatggact acatgcagca gagtgggctt taggggggat tttttcagaa aaagattatg
    12781 tctcactgct tgaagaacag ttaaagacaa tcgctgagat caaagagcta tcagttgaag
    12841 aagttaaaaa aaatacttat caaaacttgg aacgtttcat tagattaggt aaataaaaaa
    12901 gagatgtgac acaactagtg tcgcacctct ttttggcttt ctttgtataa aagtaaactg
    12961 tttgattaat aaatgaatct tagtaccaac cgtttgcttc ccagaatgct ttcgccgctt
    13021 cccaagaacc ataacgtgaa gtaacatatt gttctgctac tctttcttgg tttgcagcag
    13081 agtagtcacc atttaagtaa gaagaatcta attggtaacg tccgatgtaa cgtccgttcg
    13141 ttgctgtgta agaaccgctt gattcttttt gtgcgatcca ttcttttgca gagcttgtgc
    13201 ttgctggagt agcagcagtt tctgttacag caggagcagg ttgtgtttca gcaacaggcg
    13261 ctgcttgttt ttccgtttga accgtttctt gtacaacagg ttgttcagct tggactggtg
    13321 cttcttgaac ggctgcttga ggttcagcag ctgcttgtgc agagccttct gttgggattg
    13381 ttaattgttg tcctgagta
//
LOCUS       DAIGTA010000068        12966 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.071, whole genome shotgun sequence.
ACCESSION   DAIGTA010000068 DAIGTA010000000
VERSION     DAIGTA010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.071"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..1179)
                     /gene="iadA"
                     /locus_tag="NOB43_002302"
     CDS             complement(<1..1179)
                     /gene="iadA"
                     /locus_tag="NOB43_002302"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCI0983137.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     S"
     gene            complement(1336..3075)
                     /gene="yfcC"
                     /locus_tag="NOB43_002303"
     CDS             complement(1336..3075)
                     /gene="yfcC"
                     /locus_tag="NOB43_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCI0983138.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(3848..4462)
                     /locus_tag="NOB43_002304"
     CDS             complement(3848..4462)
                     /locus_tag="NOB43_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0983139.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(5068..5445)
                     /locus_tag="NOB43_002305"
     CDS             complement(5068..5445)
                     /locus_tag="NOB43_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983140.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(5745..6626)
                     /gene="galU"
                     /locus_tag="NOB43_002306"
     CDS             complement(5745..6626)
                     /gene="galU"
                     /locus_tag="NOB43_002306"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI0983141.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(6669..7688)
                     /locus_tag="NOB43_002307"
     CDS             complement(6669..7688)
                     /locus_tag="NOB43_002307"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI0983142.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(8321..9325)
                     /locus_tag="NOB43_002308"
     CDS             complement(8321..9325)
                     /locus_tag="NOB43_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0983143.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(9338..10387)
                     /locus_tag="NOB43_002309"
     CDS             complement(9338..10387)
                     /locus_tag="NOB43_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0983144.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(10404..11225)
                     /locus_tag="NOB43_002310"
     CDS             complement(10404..11225)
                     /locus_tag="NOB43_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0983145.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(11212..11991)
                     /locus_tag="NOB43_002311"
     CDS             complement(11212..11991)
                     /locus_tag="NOB43_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0983146.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(12008..12478)
                     /locus_tag="NOB43_002312"
     CDS             complement(12008..12478)
                     /locus_tag="NOB43_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0983147.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(12490..12909)
                     /locus_tag="NOB43_002313"
     CDS             complement(12490..12909)
                     /locus_tag="NOB43_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HCI0983148.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
BASE COUNT         3805 a         2828 c         2075 g         4258 t
ORIGIN      
        1 acttttttcg aaagtccccc atactttgac ttctttttct tggaccatta tttctccttt
       61 agcgataact gtatcaatat caagcgtttc tttatccaag atacacagat ctgcatcagc
      121 accaatttcg atttttcctt ttttatccaa tttcaatata cgtgctggat tactggttat
      181 agctcgtaag gcgatttcca aagggatact ttctttttgc acagcttctt tgatccctac
      241 tagcaatgcc ttggcacttc ctactcctaa ccctaggaaa tgattgtttt catcaaaata
      301 aggcaagctt ccttgtccat ctgaggtcat cgtgaaatta tctaaagaaa catcttcctc
      361 gatcaatcgt ttcagtgctt tgctgaagcg aacttcacca tctgtcttct cccaaaaatc
      421 aggatcttcg ctagcagtga agtcaatcgt gccaccacgt ttggcaaatg ccacgcaagc
      481 ttcaaataat tctggtgtgc gatttgcatg agtaggcaaa aattgtgtga tcggaatttc
      541 tgtttcttct acgattcgtg tcaatagctc tagctttctt tttcctccgc ctaagtggac
      601 attgatgatc ccagcttttc cggataacat gcctcctaca cgagcatctg ctactgcacg
      661 agcgaactct tcaaaacttg gctgagaaga acggtgatcg gatactgcga tttctccgat
      721 tccgataatt ttatcaattg tcaaaaagtc tttgatgata gaatctgtta ctgtttttac
      781 cggcaatcgg tacgaacctt cgtatacata agtggagatt ccttctgctt ccagaccttt
      841 cgctttgctg atcaacgcag tcatatctct accttctccg tctgttccca aacaaccgac
      901 aactgtcgtt acaccagctg tagtcaattg gctcaatgtg acttctggcg ttcgattttg
      961 ataaccgcct tctcctcctc cacctaaaat atggaaatga cagtcaatga aacccggggt
     1021 tagtactttt ccctcacctg aaagttcttc tacttccact ccttcgtagc cgccttctag
     1081 ctgttcttct acagccaaaa tcttcccacc ggcaatcagt acatccattt ttcctaagta
     1141 atctggtgca aacacttcaa tttgtcgaat gattttcata catttttcct ctttctttaa
     1201 gtataactga tgataggatc ttaaaaaata atccaaacga taggatcttt actcctttga
     1261 ttttaccgta aaatgacggt tcttggagtc cttatctact gtttggatta cttttttatt
     1321 tacaggtctc cagtactact gcagacctat tgcaatggca atcatgatga aaatagttcc
     1381 taaaacaaac aggaatcctt gcatcttgat ttggaatctt gcccattttg cccattcgat
     1441 ccgtgcaaca cctagcacac caatcaagct ggctgatacg ggtgtaaaag cgtccataaa
     1501 acctgaacca agctgataag caagaactgc tacttgtctg gatacaccta ctaaatctgc
     1561 cagtggagcc atgattggca tagtcaaagc tgcttgtcct gaatttgatg taacaaccaa
     1621 gttgaacaaa ctttggaaga tgtacatcgc ccaagcacca atgacagctg gaacaccggt
     1681 caacgccgtc ccgatcccat gcaaaatcgt attcaaagct gaaggaacag atgcatcaga
     1741 tcctcccaag acaagaagaa tccctttggc catacctact acgattgctg taccagctaa
     1801 atcagctgca ccagattgga aagaagaagc gatgtcattg actttcattc catctaattt
     1861 gaaaagaaca gcaatgattc cagcaactaa tcccatcaca aagaattgag aagcgatttc
     1921 tggaatgtaa tagccttttt gagtcacgcc ccaaacgatc cagacaagga caactaacat
     1981 ctctaataag atcaatttat gcccaagcat gaatttttta ttttcatcag atgtcttttt
     2041 gatatgagaa cggaaataat catctgattt gtaagtcaac gaactttctg gttttttacg
     2101 gattttttct gcatatatca tcatataacc agcggctaat gcagtaacaa ctacccacat
     2161 aatcaatcgg aatgtcgcac cagacaacac ggggattcca gcaatccctt gagccaccgc
     2221 tacgctaaac gggctcatcc aagaggtcgc atttccgact tgagatgcga cataagtcac
     2281 ggttactgct acgatcgagt catatcctaa cgcaatgaca aatggaacca tcaccattga
     2341 gaatggaatt acctcttctg ccatcccgaa tgtagcgcca ccgaatgaaa aagcaaagaa
     2401 taatagcggt aaagctaaac gctccagtcc cttagtttta ctgataaacg catagatacc
     2461 tgcgtcgatc gctccggtac gcataataat accaaaagca cctccaacaa caaggatcaa
     2521 tgcagcgatc cctacagcag atccatactt atctccagat actagtcctt caaaaacaaa
     2581 atttaagaaa ccaaagccgc caaaatcatc tgttccccat attttggctg ttttatgcaa
     2641 ttttttagaa gtatcataga tattttcgcc gtactgatcg taaagcacat catctgtcaa
     2701 ggagatttca tctagttttt cctgcgtaag atttttttct ccgtcagcaa tgactttttc
     2761 caatcctttt tccggaacat ccagtttttc acgttctgct ggatgatctt gcagttcttc
     2821 taattgatca aacacatacg acttatccag ctcgtaagca taacggaagg aatcttgacg
     2881 taaaacagta cgagtacttg tttcgccatt tgcatctttg tattcaatat cttgcgtgct
     2941 gaactttcct gctggaacga caaaagtcag tatccatgca aagatgacta caccaaaaat
     3001 aatgacatac gtatggggtg tcgataattt agtgaagtcg cgtttcggtt ttcctgaaga
     3061 atttgttttc ttcaaattta tttcttcctt tcttttttca gtaattttga tgaataaaaa
     3121 atggataatc aaatgaatta tacagtaaaa atgacatttc cacatgaata atttattaga
     3181 aaatcacttt tttctatttt gttttttttc tcctatgtat gattattttt ttctctttcc
     3241 atttatatta agtattttat ttctctgttt ttccttaaaa ttcttttttt atttttagat
     3301 tagagaaaat ctcgtcctgt ttttttcatt ttacaatcat tgaaaaattg aatttcattg
     3361 caaaaaaaat aataaacact tataaatatc cattatctat ccttcaattt ttgtgtattt
     3421 tatttctatt agaaaaaggt atcctgttgg acaattttgt tatatcaggt aaacttcatt
     3481 gcaataatga taacaaatgt actataatta ctttgtaaag agttttgggg aagactcttt
     3541 catcaacgtg tattaagaga caagaaagaa tccatatgga ttctttcttg tctctttttc
     3601 cactactttt tatttttctg acactacata ttcttataac tcatttctca taactgtgaa
     3661 acaacttata aaaataacaa actttaaaca aaacaagctt aaaatcaaag atgatccatc
     3721 ttaaaataac taaaacaaaa aaagtagtcg ttgttaatcc tcattaataa tcgttttctt
     3781 tttttcaaac gctccatttt tatgtggaac attatttttt taaggaactt tgtcaacatg
     3841 tggataacta ttttccactt gtgtcctgga ctagctgttt tgctgtaaaa tacaaaactt
     3901 gctgcagcaa aaagatcgtt gcaagagagg ctgttccgca gatcgctgga tctagatttg
     3961 gcaaagtcaa gactgcatca tgtaaattgg cgtggttgtc caaaaccaaa tcagcaaatt
     4021 caaataatcg caaaccactg ctatgttgcg atttgatact tcgtgacaaa tcaaatccag
     4081 taacaatgat taatggatga ccattttctt tgatccactg agctagttcg atgattgccg
     4141 ggtttcttcc ttcattcgaa agaagaagaa aaatgtcttc tgatttgaca gaaagctgat
     4201 caataattgc ctgtcctgca ccttctagcg tttcatagac acctccggct ggattttcaa
     4261 tcaatatact tggtacaaga tccggggttt gatcccaaaa ttcaaatgct acaccactta
     4321 gtgtgcggct agcatatatc tgcaatctac caccttgatt aatttgtttc gcgatccaag
     4381 tgccagcttg aagcatcagc ggctcttcta tccttaattt ctcttccaat tggtgataat
     4441 agtcaaaata acataaactc atttatctct cccgcctagc tatacttgac atgaatagaa
     4501 acagctgcct aatctaagga agtacataaa aaaacagtag ttagacagta acacatgtgg
     4561 tctttgctgt ttcaaacaca aaaaaggcat tgaacgaata cgcccaatac cttgacatag
     4621 caaataaaac aacgtgcaga ccatggaaaa tatctacata ggggtagaat tttcacccta
     4681 gattaggtac aataaattag gtcgatgcac tgcattgact atggcaaaat gatcggtcag
     4741 ggtgtatgtg tgtgactggt cattccctga ttcttagcgc caactaaggg tcagggagcc
     4801 tttttttatt cagctgtttc tatctgaatt tattgtaagt aatctcttat ccaagtgcaa
     4861 gcaagaaaat acaaaaaaac attggtatga tttatatata tataaataac ataaaaaaag
     4921 gaatggctta tcccgataca acaagcattc ctttaaaaaa gattctttta tataagtgaa
     4981 aaaagctttt ttccaccaat taaataaatc tctcatctca atagtttatc cattatttta
     5041 tctttttttg cgtataccta ctaaatatta ccgtcttctt ctcgttcttc tactttgttc
     5101 gagagaatct gtactagaaa aagtagttgt atgtctacct tttctgccta tccgagactt
     5161 tcttttcata tatgggatat aaatgattag atacagtaca gcaaaaaata aagcaaatac
     5221 gcaagcttcc caactaccta acgccaattc aaccatcaag gtagcaaccc caacggatgc
     5281 tgcataccag ataaaaatca gaaacgtttc tttttttctg accatgcgaa acatgataaa
     5341 tagactaata agcaatagtg gcaacacaaa tatccaattg cttccttcca tcagccactt
     5401 gagtatatca agcagcgact gtgcaacagc gactaatttt cccatagtga acacacacct
     5461 ttttttataa ttaaaaaatt cgccttttta ttctactatg aatcttctgg cttggctttc
     5521 atttctctta tgtaatcatt ttcttttata caacttaaaa aaaaattaaa ccattagcat
     5581 aatattttct gaatctattc acgaaagtct ttttctatct ttcgttttcc acgactcaac
     5641 tgatctagag tcaaaaaact aaaacgacag ttgcgcaaat gacgcacaag ctgccgcttt
     5701 aataacaaat agcctttcat tctcagcagg ccacttattt ccagttaact ttctgttctt
     5761 agctttttac tcaactggat aatatatgca cttaatgaag tcccaatttc cgaatgttga
     5821 agtccatatt caatatttgt cttcatatat cctaacttat cgcctacgtc gtatcttttt
     5881 cctttaaact ctctcgcata gaccgcctct gtctggttaa gagtctgaag tgcatccgtt
     5941 agctgtatct cgtttcctgc tcctggttct tgagtttcta atatctcaaa tattttagga
     6001 gtcagtagat aacgtccgat aatggctaaa ttacttggtg cttttcccat ttcaggtttt
     6061 tctacaaacc cttttactct gcaacgaccc ttttcgctat ctgttttagg atcaataatt
     6121 ccgtatttag atgtttcatt ttctggtaca cgcatgacgg caacagcgga agcttgtgtt
     6181 tcttcataat ccatcatcaa ttgttgagtc aatgggatat catctttcat caaatcatcc
     6241 cccagcatga cgacaaacgg ttcatttcct ataaatgctt ttgcttgaag cacggcatcc
     6301 cccagtcctc ttggatgaga ttgacggatg aagtgaagat tgacttgagt cgtttcttca
     6361 actaaagcga gtaattctgt tttttccttt tcccgcaaat tgttttccaa ttcgatattt
     6421 gcatcaaagt gatcttcaat gggtcttttt tcttttcccg ttacgatcaa gatgtcttcg
     6481 attcccgaat ccaatgcttc ttccacaata aactggatcg ttggtttatc cacgattgga
     6541 agcatttctt ttgccatggc ttttgttgcc ggcaaaaaac gtgttcctag cccagcggca
     6601 ggaatgactg cttttttgac cttcacttgc tgttcctcct aaacgacgat taactattga
     6661 tcatctattt aacgaagaga aaattcattc tccatttttc cgtcacgtaa catgatttct
     6721 tttgctgctt ttttgatatc ttctccatta tacaaaacat tatagattgt ttgagtaatt
     6781 ggcatctcaa cacctagctg ttgagctagc tctactgctg cttttgtcgt tgccacaccc
     6841 tcaacgacca ttcccatgtt ttctagaact tcttccagct tatgtccctg tcctaacaag
     6901 ttaccggcac gccaattgcg agaatgaaca cttgtacaag taacgatcaa gtcccccaca
     6961 ccactcaaac cgataaatgt cagaggattg gcacccatcg cgacaccaag acggctgatt
     7021 tctgccaatc ctcgagtcat gattgctgct tttgcatcat ctccgaatcc taatccatgg
     7081 atagcgccgg caccaattgc aatgatattt ttcagtgctg caccagtttc tacgccaatc
     7141 acatcattat ttgtataaat cctgaaataa tcattcatga acagtttttg tacataggct
     7201 gctgcttttt gatcaatact tgcagctgta attgttgtga tatcatgtac tgccacttcc
     7261 tcagcatggc taggaccaga taatacaaca attgcctgtc ttttttcttc tggaatttct
     7321 tcagccaaaa cttctgagat tcgtttatgc gtatcttgtt ctagtccttt acttgcatgt
     7381 ataatgattg gcttagtatt cattttacca ataagttcct gtgcgactga acgaatcgct
     7441 tttgttggaa caacaaataa aatagcatct gcgttatcca ctgcttctgc caattcttta
     7501 tatccgataa tcgattctgg gatcgtcaaa tcaggtaaaa aatgctgatt tgtatgatac
     7561 ttattgattt catcaatctg ttcaggtaca tttccccaaa tacggacatc atgcccgttt
     7621 tctgccaatg tttgtgctaa agcagtgccc caagatccag gaccaagaac tgcgattttt
     7681 tgtttcatgg atattcctcc aaataaataa ttgataattt ccattatagt atacatttct
     7741 taaagttggg actaatttcc attgttttta agtgtttgtt tacttctttt atcgttttta
     7801 cttgaaataa tcaatgatat gttacaatag tctacatttt atttttacac tcgttatgct
     7861 ttgcttgttc ctaagaggaa gcagttttga caatgttact accagcatta ctattaggag
     7921 gttaggaaac ttctcctagt gagtattgat ttaaaataca taagagacag attgaacatt
     7981 tctaaatctg tcaggtcctg caacggacag attgtctctg ttgacggttg acataggaac
     8041 ttttgtttta gtcaacattc tggatacaaa acgctatgta aactggcgca actcgttgta
     8101 cttggacttt tactacggat ccatgcaaca actaaatagt actattgcat aacaaaaaat
     8161 ggttggcacc cacatgtccc attaaacaga ttataagttg aactgtagat aatgcaaaaa
     8221 atgtgtttta taacgtaatt gatgccaata ttttaaaaaa ataaagggag cagttatcgc
     8281 tgctctcttt attttttata ttctttttat ccagtctatc ctaataatca aactgacgat
     8341 agtagcggcg tatctctaat ggatggcagt tcaactgctc cacatgagca tcgatgcgtt
     8401 gtgtcactac atgcatcaat aagaaagaca aaacacgtcc gcgatatttt tcactgatac
     8461 cttctactgg atagtctttt gtgtctatca atgtataatt gctgcaaatt tttggcaaaa
     8521 gtttagccac acgttcagat aacactctct gttcatcttc gcctaaaaat aatgtgactg
     8581 gggttgtttc ttctacgatc tctaacgtcc cgtgaagaaa ctcggcagca tggatagatt
     8641 tcgatggaag ccagctttgt tcttcccagt aacacatggc atatgaataa acagctcccc
     8701 attgattccc tgctccaata aaataatgca tactatcacg tcgatgtttt tctgcaaatg
     8761 ataagccaaa tgcatctgct tttttctctg cttccactaa ccctgttggt aaataacgtt
     8821 cgagctgttc atagtattct gaataagctt cgaattctcc attcaaatac atcaatcgat
     8881 ctgctgccat aaaaaatttg atttgttctg ttccaggagc tggataagtg accacaaaat
     8941 cgcatagctg agacaactta ctgttcgctt tatcgataaa tccaatcagt gtcgctccta
     9001 ctttcttgat ttgttctact gctttcacta cttcttgagt tgtaccggta acagaggaca
     9061 aaataacgat agaatctttt gttaatcttt tgtttccagt agtgtaatat tctgcagcat
     9121 gctgtacaaa gacaggcaag ttgcttttcc cattcatata agtgacagct tgcatcgagg
     9181 aagcatacgt tccaccgatt cctagataat agacagcgtc aaatttttcc gcataaagtt
     9241 tatcgatgat ttcttctact tgcggacgta aagctagtgc gccttttatt gctttgattt
     9301 gttcttcttc attgaatttc agcatgattt ccacctctta taatttactt ttcaagactg
     9361 tatcaaagtc ttcaaaaatc tttttgttca agtcaatacc tttagctact gcggttttat
     9421 aagcgaatag ttgaaacgga acgacaagcg ctaatacaga cagatattca tcacattcta
     9481 ttgctaatcc aagtgttttc tcgtttcttg ctttttttgt ggtaatggtg agagtctctc
     9541 caacgtaccg actcatatat ctttgcaact tttgcgaacg ttccttattt acactttccc
     9601 cttcaataaa gaatagcaaa tgcgaagcat ctgcctccag gtatgggccg tgcatataag
     9661 cttctaactc aaatccttgt gacggaacgc ggattgtttc agtcaatttc gtctctgctt
     9721 ctttagctgt tccccagttt ggaccatatc caatggtgac gaaacgctgt gctaaacgaa
     9781 ataaactttg atatccatca aaaaattctt ccgttttttg aataatcgct ggtaaatggt
     9841 tgattatttt gcgcaactgt tgcatgtagt cttgttctat ttttttgctg attttatttt
     9901 tacttattcc aattcctatc cctaagagta gtaactgtaa aacagtcgca gaatagcctt
     9961 ttgtaacgaa gcctactgat tctaccccgg cacctaaatc aataatttgt gcagcttcta
    10021 aagcaagtgg actttgcacg tcatttgtga tagcaacaac aggtaaccct tgtttttgta
    10081 tcatttttac tgcttcaaca gtagaagcac ttttcccgct ttgtgacaca gcaatcacag
    10141 tatcgattga aggagaaagt tttccataat tgaaaaaata aaaaggttct tgaatatcga
    10201 cagtaagatc accataagat tccaatgctg gcttcgctgc taaacaagcg ttataagatg
    10261 aacccgttgc taagatcagt aaattcactg tttttttcat atgttctctt gtcgaaaaat
    10321 cattcttttt caagatcgta cttagtactt ccttttcttc atagatataa tcttgcatcg
    10381 taaacatttt ctctgctcct tttttaaaaa atccctatcc acgaaccaaa aattccaaag
    10441 aaagctagtc cgatcaagat cgttaatggt ttcacttctt tcttcaatag ataaaacact
    10501 atgccaaatg ctccaagaca taagatattt ggaacgatat catcaaaaat actttgaaca
    10561 gtcacagcat tttctcctga accgattttt aaaggaatat tgatggtgat catcgtggca
    10621 gtcattgctc caacgaccat cagtccaata atagacgcgc ctaatgtcaa actttccatc
    10681 ataccgtttg cctggatctt tttcaaaaaa cccgttccta agcgatatcc ccaacctgtt
    10741 gctagatagc gaaacagaat gtgcggaata ttgaaaatca aaatgaacaa gatagggcct
    10801 aaaatatttc cttgcatggc taaagaggta cccacacctg tggcaatcaa tcgcaaagtt
    10861 ccccaaaaga aagaatctcc taaccctgca agaggtccca tcaaagatgt tttgatacta
    10921 tcgatcgcag tcacatcaaa ttcaggatca tccttatttt cttcctccat tgcagccgtg
    10981 attcctaaaa tcagtgtaac gatatgtggg gtcgtgttaa aaaactctag atgccgtttc
    11041 aaagctgctg ccatttcttc tttcgactga tataactttt tcaaaatcgg aatcattgca
    11101 taaacataag ccatattcat ctgacgttca taattccaag aaaactccat ttgaaaagaa
    11161 cgccaaaata cgtgatttag ctcttttttc gttattttgc tgtttttgat ctcagaattc
    11221 ttcatcttct tctacctccc ctgcagttgt ttgaagtggt agttgacgga cattcataat
    11281 attgactacc acaactgcta aaatcgcacc aaaaatagct actccggtca caggaatctc
    11341 taagtaagaa gctatagcaa aacctaagaa aaaatatggt gcaacttgtt tgttgatcag
    11401 caaacgagca agcatcgcaa aaccaagagc tggaatcaac cctgtagcta ctgacaaccc
    11461 cttttgaacg aagtcaggaa tcatatttaa tagatttccg atcgtattgc ttcccaccat
    11521 ataagaaacc attaccacaa caccaagcat caaggaaaga ccgataccgg caagcaagtg
    11581 catatgctcg actcctttat aatttccttc ttctgcataa ttgtctgctt tatggttcat
    11641 aattggaatc aaaagcccta agtaaatatt tttcaatatc aatgtcaacg tagcaatcgg
    11701 caaacctagt aaaagcgcgg tttctgtacc ggctccagct gtaatagcaa aagccgtccc
    11761 taaaatccca ccggtcacaa catcaggtgg aatcgaagca cctactgaga acgatccgat
    11821 aaatgctaac tctaaagttg cgcccataat gatcccagtt tttacatcac ctaacacgat
    11881 tcctgtaaac agccccgtca caatcggacg agaaagcaac gatgtcccta gtgcatattc
    11941 tgattgtgcg acaaatgcaa caattcctaa taagactgct tgtacaatca ttgaggttct
    12001 tcctttctta caaaacttct cttacatcca cttttttatc tgctggtact tgacggattt
    12061 ctacttctat ttgtttgtca attaatcgtt tcaagcgttc ctcctcttct ggtaaaatat
    12121 ttaccgcttt tccgatgctg cgagtaccag gttttgcctt gatccctcct aagttgatgg
    12181 ttttgatttc tggatacgct tctgccagct tatatgcatc ctcgatcgat tccactacga
    12241 tgaataactt atatttatct gtcaccccgc ttttcaacgc ggcaatcgag tcatcaattg
    12301 atttgatcac tagtttgact ccttgtggct tggctaattt gatcgttgtc tttcgtatct
    12361 cattcgtagg tacatcatca ttagcaatca aaatacagtc tgcgcctatt gtttgtgtcc
    12421 atgaaaaagc tacttgtccg tgtaataacc gatggtcgac tcttgtcaat acaatcattt
    12481 ttcttcctcc taaaattcgt cttcttctat tttctgattg agccgctcgt tacaaaactg
    12541 gatcattttt tttgaatcag ttagcacctg ctggatcaaa acagttgtct ctacttcagc
    12601 gtccaaccga gatactagct caatcaatag tggcaaattc aatccggcaa cgagatagac
    12661 atgatcccga ttgatatatt gtaagaattc gttgttgaca cttccgccaa aaagatccgt
    12721 cagaacaatg atttctttat ctttgtacct cataaaaagc tgccttactg tttccgctaa
    12781 atcaaaattc tcatcagtat agcaatcgaa tacagtaata gaatgatttt tcccatagat
    12841 cagctctaat gaatctaata tccctgaagc aaattttcca tgggaagcta agataatttc
    12901 tctatccact ttttcatctc ctcttttcac ttacacatac taaaaaagca agttgcatgc
    12961 caaaat
//
LOCUS       DAIGTA010000069        12802 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.072, whole genome shotgun sequence.
ACCESSION   DAIGTA010000069 DAIGTA010000000
VERSION     DAIGTA010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.072"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="NOB43_002314"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="NOB43_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCI0983149.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="NOB43_002315"
     CDS             complement(323..892)
                     /locus_tag="NOB43_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HCI0983150.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="NOB43_002316"
     CDS             1078..1980
                     /locus_tag="NOB43_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0983151.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="NOB43_002317"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="NOB43_002317"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCI0983152.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="NOB43_002318"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="NOB43_002318"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCI0983153.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="NOB43_002319"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="NOB43_002319"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCI0983154.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="NOB43_002320"
     CDS             8548..8733
                     /locus_tag="NOB43_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HCI0983155.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="NOB43_002321"
     CDS             complement(8795..9991)
                     /locus_tag="NOB43_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0983156.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="NOB43_002322"
     CDS             complement(10161..11597)
                     /locus_tag="NOB43_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI0983157.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="NOB43_002323"
     CDS             11890..12699
                     /locus_tag="NOB43_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0983158.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3820 a         2686 c         2263 g         4033 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaatttt tgtcacaacc ttttttgccg agtaaacggt gttcaaaagc
    12781 cagtttctcg gtatgaagtc aa
//
LOCUS       DAIGTA010000070        12771 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.073, whole genome shotgun sequence.
ACCESSION   DAIGTA010000070 DAIGTA010000000
VERSION     DAIGTA010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.073"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="NOB43_002324"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="NOB43_002324"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCI0983159.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="NOB43_002325"
     CDS             complement(2261..2512)
                     /locus_tag="NOB43_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HCI0983160.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="NOB43_002326"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="NOB43_002326"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HCI0983161.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="NOB43_002327"
     CDS             3462..3680
                     /locus_tag="NOB43_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983162.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="NOB43_002328"
     CDS             complement(3969..4481)
                     /locus_tag="NOB43_002328"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCI0983163.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="NOB43_002329"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="NOB43_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCI0983164.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="NOB43_002330"
     CDS             complement(6934..7377)
                     /locus_tag="NOB43_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HCI0983165.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="NOB43_002331"
     CDS             complement(7378..8166)
                     /locus_tag="NOB43_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0983166.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="NOB43_002332"
     CDS             complement(8163..9104)
                     /locus_tag="NOB43_002332"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HCI0983167.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="NOB43_002333"
     CDS             complement(9281..9868)
                     /locus_tag="NOB43_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HCI0983168.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="NOB43_002334"
     CDS             complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="NOB43_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HCI0983169.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11699..12709
                     /gene="gap"
                     /locus_tag="NOB43_002335"
     CDS             11699..12709
                     /gene="gap"
                     /locus_tag="NOB43_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI0983170.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3530 a         2858 c         2270 g         4113 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgtaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgtattaa ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat
    11701 gacagtaaaa gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat
    11761 caaagaagtc tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat
    11821 gttagcacaa ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc
    11881 aacagaagac tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc
    11941 aagcaaaatc ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt
    12001 ttatacatct gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat
    12061 ttctgcccca gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga
    12121 tgaaaacgac aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc
    12181 ttatttctta aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta
    12241 cacttccaca caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg
    12301 ttcagctgct gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt
    12361 tatccctgag ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg
    12421 ttcattaact gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga
    12481 agcaatcaaa aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt
    12541 ttctagcgat gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt
    12601 aacaactgct ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg
    12661 atttacttgc caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc
    12721 aatcgataaa agaagccttt gactggatcc agtcaaaggc ttctttcttt t
//
LOCUS       DAIGTA010000071        12638 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.074, whole genome shotgun sequence.
ACCESSION   DAIGTA010000071 DAIGTA010000000
VERSION     DAIGTA010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.074"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            22..591
                     /locus_tag="NOB43_002336"
     CDS             22..591
                     /locus_tag="NOB43_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HCI0983171.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            578..1438
                     /locus_tag="NOB43_002337"
     CDS             578..1438
                     /locus_tag="NOB43_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0983172.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            1628..2332
                     /locus_tag="NOB43_002338"
     CDS             1628..2332
                     /locus_tag="NOB43_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0983173.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2337..4172
                     /gene="walK"
                     /locus_tag="NOB43_002339"
     CDS             2337..4172
                     /gene="walK"
                     /locus_tag="NOB43_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HCI0983174.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4169..5485
                     /locus_tag="NOB43_002340"
     CDS             4169..5485
                     /locus_tag="NOB43_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983175.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5486..6355
                     /locus_tag="NOB43_002341"
     CDS             5486..6355
                     /locus_tag="NOB43_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HCI0983176.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6410..7219
                     /locus_tag="NOB43_002342"
     CDS             6410..7219
                     /locus_tag="NOB43_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0983177.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7322..7951)
                     /locus_tag="NOB43_002343"
     CDS             complement(7322..7951)
                     /locus_tag="NOB43_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCI0983178.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8121..9413
                     /locus_tag="NOB43_002344"
     CDS             8121..9413
                     /locus_tag="NOB43_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0983179.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9489..10151)
                     /locus_tag="NOB43_002345"
     CDS             complement(9489..10151)
                     /locus_tag="NOB43_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0983180.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10376..10660
                     /gene="groES"
                     /locus_tag="NOB43_002346"
     CDS             10376..10660
                     /gene="groES"
                     /locus_tag="NOB43_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCI0983181.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            10711..12336
                     /gene="groL"
                     /locus_tag="NOB43_002347"
     CDS             10711..12336
                     /gene="groL"
                     /locus_tag="NOB43_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCI0983182.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4207 a         2153 c         2750 g         3528 t
ORIGIN      
        1 atgaaaaaag gagcggttat gatggaaaaa atgcgtcagc aattaatgga gtgggggaag
       61 gaactagaaa cattccgtct gcctcactgg gaagaactcc ctgacttaga actttatatg
      121 gaccaagtca gaacgttagt tgatcgttat ctttcacctg tgatacaagg agaaaagcat
      181 ccattgctta cctcttctat ggtaaacaat tacgttaaac taggtttgat accagcacca
      241 gttaaaaaaa gatataacaa agaacacgta gcatttttac ttgcaatcac tacgttgaaa
      301 caagtattga ctattcctga aatcaaagaa gggatattgt tccaaggaaa aacagtagga
      361 attcgtgaag cctataatct attttgcgat gaacaagaag cagctgtgtg gatggtcagc
      421 caattagcac aaggtaaatc tcatccgcaa aaattcgacc aggcaacccc tgtagaatat
      481 attgctgtaa gagcggcaac tttatcgttt gcaatgaaac ttcttgcgga aaaaacgatt
      541 gttctagaaa ccgaatattt aaaagaggag aaaacaaatg aaaaacaata aaatcgcaat
      601 tttagtagat tcaggtacgg atgtgccaga agaattgata aaaaaatacg agatgtatat
      661 gatcccattg aaaattattt ataaagatca ggtatataca gataaaattg acattacctc
      721 tgaagagatc tatcaacgtt tgccagagga aatccctggt acatctttgc cggatggtga
      781 gtcgatcaca gaaatctttg agcaaatcaa aaaagacggt tatgaaaagg tacttgcggt
      841 aacaatttcc agtggattga gcgggacata taatgtggtt cgtttaattg cacaacagca
      901 agaagaattg gaagcatatg tactagatac gaaaaatatt ggtattggtg caggtttttc
      961 tgcgatccaa gcagcaaaat ggctggaaga aggagtagaa tgggatcaac tgatcagtaa
     1021 tctgaatgag ttagtcgaaa gaacaaaagt tttctttaat gttgcgacat tggaatatct
     1081 tcaaaaaggt ggacggatcg gtttagttgc ttctattgta ggaaccgctt taaagcttaa
     1141 cccaatcatc tcatgtaatg aagaagggat ttattacaca gtaggaaaag ctaggggacg
     1201 taaaaaaagt ttggataaaa cggttgctta cgtcaaagaa aaaatcggta atgcaaaggt
     1261 cttcaactta gctgttgccc atggggatgc gaaagaagaa gcaattgaaa tggaagcgag
     1321 acttaaaaga gagttcccac aagcaaacca aatctacttt ggccagattt ctccggcatt
     1381 agtagtccac actggtccgg gattattggg tgtcggtgta caagttttag aaggataaat
     1441 caaaaaaagg aaacactgag gtgaaaatca gtgttttcct tttttattga agttagaaca
     1501 aaaaataata aagtattttg cactttcatt ttaattttct cttttgtttt ataggcaaag
     1561 atgaaacaaa agcagaaata cggtataatg agaaggtatg acaataatat ataagaggtg
     1621 gctctttatg aaaaaagttt tagttgtcga tgatgagaag ccgatttcgg atatcgtcaa
     1681 attcaattta gccaaagaag gctatgatgt ttatactgca tatgatgggg aagaagcctt
     1741 ggaaaaagtt gctgaggtag aacctgattt gattttactt gatttgatgc tacctaaaat
     1801 ggacggctta gaagttgctc gtgaggtacg caaaacttat gatatgccga tcattatggt
     1861 aacagccaaa gattctgaaa ttgataaagt cctaggctta gagttaggcg ccgatgatta
     1921 cgtgaccaag ccattttcca accgagaatt agttgcacgt gtcaaagcaa atcttcgtcg
     1981 cggtgccacg gctgcgaagg aaccagaaga ggcagcacct gcggaattga cgattggtga
     2041 tttgacgatc catccagaag cttacatggt gacgaaacga ggagaaacaa tcgagttaac
     2101 acatcgtgaa ttcgaactac tcttttactt ggcgaagcac cttggacaag tgatgacaag
     2161 agaacattta ttacaaacgg tttggggtta tgattatttt ggagatgtac gaacagtgga
     2221 tgtaactgta cgtcgtttgc gtgaaaagat cgaagataat ccaagccatc caaattattt
     2281 agtgacacgt cgtggtgtcg gttactattt gcgtaaccca gaacaggagt aattggatga
     2341 aaagaaaagt ccgctttttt cgatcagtca attttaagat cgctattacc tttattctga
     2401 ttttattgat ctcgatcgaa attattggtg cctactttat acgtggttta gaacgttcca
     2461 cgatcaatac atttattaaa gatatgaatc aaacggtgga atcattagca acaacaatca
     2521 gcccggaatt gaatcgaaaa gataatgcag atgatgaaga ggtaaatgcg aatatcaaaa
     2581 gatttattga aaacagtgcg actagcgata tcatcgaaat acgggtcgtt gacgaaaaag
     2641 ggatcatccg aggaacaacc gatgtcaatg aacaaagcgc tgtgggaaag aaaaatgatt
     2701 atgttgatat caatgatttc acgactaaac gttatgttgc tttagataac gacgataaac
     2761 gggtgaatat caatgttcaa ccgatcctgt ccccgaccgg cgatgccgtt atcggggctc
     2821 tttacgtcaa aagtaatatc gaacaaaaat attcggaaat caataacaca gcagtcattt
     2881 tctttactgc ctcactaatt gcggcattta tttcaatgat cgtatctgtt ttagttgctc
     2941 gttcgattac acagccgatc ggtgaaatga gagaacaagc cattcgaatc gctagaggag
     3001 actacagtcg gaaagtcaaa gtgcatggac aagatgaact tggacagctg gctgatacct
     3061 tcaatcagtt agctgaacgt attgaagaag ctcaagatac aatggaagct gaacgcaatc
     3121 gtttggatag cgtgctatcc catatgacag acggcgtcat tgcgacagat cgcaggggta
     3181 aagtcattac gatcaatgat atggctgttt ccttgctaga tatcaaaaac gaggaagcaa
     3241 tcggacaatc gattttgaca cttttagata tcgaagaaga atatacgttg cggaaattat
     3301 tagaagatcc aaacgaaatg gtacttgacc gttcaaccag tacattggaa agtgatcaga
     3361 tgatcttgcg agtagacttt tctatgatcc gtcgcgaatc aggttttatc agcggattag
     3421 tagctgtctt gcatgatgtg acagaacaag aaaaaacaga acgggaacgt cgtgaattcg
     3481 tctctaatgt ttcccatgaa cttcgtacac cgttgacaag tatgcgtagt tatatcgaag
     3541 cattgagcga aggtgcgtgg aaagacgagg aagtagcacc aaattttttg aaggtaacgc
     3601 tagatgaaac agaccgaatg attcgaatga tcaatgacct cttaaatcta tctcgcatgg
     3661 atacaggtaa tacccagctt caattagaat atgtcaattt caacgagtta gtgaattttg
     3721 ttcttgaccg gtttgatatg atggtgggaa atcaggaaaa aaattataag atccgtcgtg
     3781 aatttacgca aagagatctt tgggtcgaag tagatacaga taaaatcatc caagtagtcg
     3841 ataatatcat gaataacgcg atcaagtatt caccagatgg gggaacgatt acttgtcgct
     3901 tattagaaac gcataataac gtggttttaa gtatcaccga tcaaggattg gggattccta
     3961 aaaaagatct gaaccgagtg ttcgagcggt tctatcgagt agataaagca cgtgcaagag
     4021 cacaaggtgg gacaggactt ggattagcta tttctagaga agtgattaag gcgcatcgag
     4081 gcgctatttg ggcagagagc aaggaaggaa aagggtcgac tttttatatc tcgctgccat
     4141 atgaacctta tgaggaggaa tggtgggaat gagaatctct gaaaaagtcg ttcgtatagg
     4201 actcattttg atggttgcgt taagcatata cttctcttat gcaatctggc tgagcccagc
     4261 aggaaaaagt tcaatcaacg tagatgagac aaacactcaa atgatcgagt ctcaaagcaa
     4321 tcgaaaaact tccgaagtct ttcttccgct tcatgttaca tggcaccatt cgggaatgat
     4381 ccaagaaacc aacagtgaaa atctcgtgta ccgattgcaa ttgatcatcg ataaagcaag
     4441 atttggaaag ctttctgaag tagtttcagg agacaaatca cagtttgaac aggtgaaaaa
     4501 tctgaactct ggttttgagt tggcctataa tgcgcctttt ttgctaagag aatacaagga
     4561 agcatttgat ttagatttag atgtgtcgaa cttggcaaaa gaaagcgaaa atatgtattt
     4621 tactagaata caattcgatc aaggaaataa aaaaatccga tttttgaatt attcgaacca
     4681 tctcgtatat gaagcaaata tttcgttgaa ttggacagat atcaataaag aattaacagc
     4741 aaaagacaca aaatggacag aaatgacaac agaaccatcg acgatcgaca cgcaatatgc
     4801 tacgaaacat tcgatcaaac tgaaaaagta tagttatatc ctgtcacagc aaccctatac
     4861 actttttaga aatgcttttt tccagaaacc agatagcgtg aaaaataatg atgaaagcaa
     4921 tgaattgatt ttttacggtg ggaatgaaac aatgtctatc cattcggaaa cgcaagtagt
     4981 tgattttcgt ggagagctgc cagagaaaaa agaaaatgct agtgtatttt ctgaaagttt
     5041 cccctatatt agcaaattag gcagttcttt agggaacctc agatattttg accgcagtga
     5101 caatacgatc gattatcgga tattcgtgga aggcttcccg gtttttggga cagacagcag
     5161 aggacagatt ggtgtggaag ttggcggtga aacgaatggt tctgtgcaag tgaatatcca
     5221 aaccagtttg aatacgattc aagtgccgat accttcagac gaagaagtag aacttgcaag
     5281 tacgaatgaa atcatccagc agttaaaagc taagggagca gatagcaaca agattggttc
     5341 agtgatcgtt ggctatacat ggcaaaatgt caaagaaacg aatcgtgtcg ttgatctctt
     5401 acctgaatgg tatgtgaaat ataaagataa ctggtattca gctaacgacc ttctggaaaa
     5461 attacctgga ttggaggcga attaattgga tttcaaaaaa atcgaatgga tatttttcgt
     5521 cgctttttta gggttgaatg tgtttttatt cagcagttat catgacgcgg tataccaaga
     5581 aaacaatgtc attcgctcta atcagactga atcaatccaa caacgtctgg ctagcgacga
     5641 tatcacttac acggggaaga tttcgtctga gaacaagcaa ggctattatc ttagcgcgga
     5701 gcagaccaat cttagcactt cattagcgaa ttatcgcaag gctggtaaaa gcggcttgct
     5761 ggcaagtggt gtgtttttag acggtgatgt tttgacgaaa tctttatcca gttcagatgc
     5821 tgaaaagaac gtgatcgatc cagataaaat tagtagttcc ttggaagatt ttttatctaa
     5881 caaagacaat attttattcg gtaatgatta tgtgtacacg aaaaactttt ctcatttaga
     5941 agaagaacca ctagaaatcc aagcaagcca agagtatgaa ggcatcccat tcaatgatga
     6001 tacagcaaaa atcgttcttt ctttagaaaa aaacgataat gattatagca tcacgaaata
     6061 catgcagacg catttatctg atatcgagca gctgcgcgaa aagacggaac tgtatacgga
     6121 agaggaagca atcaatacat tgtacatcaa taacaaaata ccaagaggat caaaaatttt
     6181 atggcgtcag ctagcttatt cctgtattct gaaagtccgg gaaaaaaatg tgtatgttcc
     6241 tgtttggcat gtagcgatcg aaacaagcga taaagtggtc caaattgaga gtgtcaacgc
     6301 tttcagcaat acgatcgtga caaacaatac tgtaccaaaa gtggaagatc aataaaaaag
     6361 cgagtataat gaaaaaagtt tacaaagtaa gaagggaagt aggagtcaaa tggctgaaga
     6421 aaaaccagct tttaaaatca gtatcctagc aagtggaagt tcgggtaatt cactttatat
     6481 cgaaagtgaa aaaaaacggc ttttggtcga tgcaggactt agcggtaaaa aaatcacttc
     6541 cttgatggct caaattgatc ggacaccgga ccaattagat ggaatacttg tgacgcatga
     6601 acatcgagat catatacatg gcgtgggtgt cttggctcgt aagtatcatt tggatgtttt
     6661 tgccaatcag cagacttggg aagcgatgga accactgatt ggaaatgtac cagtggaaca
     6721 aaaacatcta tttgagatgg ggaaagtcag aacattcggc gatatcgata ttgagagttt
     6781 cggcgtctcc catgacgcag cggctccgca attttatcgt ttccataaag aaaatcggtc
     6841 attcgtcatg ttgacggaca ccggatattg cagtgattat atgcgaggtg tcattgaaaa
     6901 tgccgatggt tatttgatgg aaagtaatca tgatcttgag atgttacgca tgggacctta
     6961 tccgtggaat ttaaaacagc gtattttagg agatagagga catctttcca acgaagacgg
     7021 tgcacttgtc atgactgatg tgatcggtaa tcggaccaaa cgaatctatc ttggccatct
     7081 tagcaaggaa aacaatatga aagaacttgc tcatttaaca atggaaaatg ttttgaaaga
     7141 aaaagatttt ggcgttggac atgattttga aatctatgat acagatccag atgaagcaac
     7201 tgagctattt tcgatttaaa cagttcaatc aataaaaata taaaaagcag aagataaaat
     7261 caatcagggt tggttttatc ttctattttt atttttttag catattaaaa aaataaccgt
     7321 attatcgact gactacactg atgtgctgct tttcatgttt ctcatccagt atctcatcta
     7381 ctaatgcaat cgcgtaatct gccatgctga tcgtactgtc gccagcagcg tttctttgta
     7441 aataatcatc acttaacaaa taagtacctg tacgtttgcc atgtggatca aataaagaag
     7501 ctggactgat ataagtccaa tgtagatttt tagattgttt caattttaac aatccttcgt
     7561 acatattgaa agctgttgga tagaagggtg catttttagg tacttggtca atcatacgag
     7621 tcgtcttttc tgtatctaag aataacgaag aggcaccccc aacgacaatt aagcgtgtat
     7681 cggttccttc aagcatctca atcaaatggg acaaagaagt ttgatgcatt tcttcttttc
     7741 ctttgggagc gttgaaagca tcaacgacaa catcaaaaga tgcaagatca gtagttgtca
     7801 actcaaataa atccttttgt ataaacggaa catctgatgg caatttttct ggatgacgca
     7861 cgattgccgt cacgtctaaa tctctggaca atgcttcgtc taaaataaat gaacctgcat
     7921 ggccagtagc tccaatgagt gcaattttca taaaaaacct ccttttttat tcctgtccat
     7981 tgtaagcagt tgctgaatat tcgtcaaaga atccgatttt tgaaaagctc agtgcgcatt
     8041 cctttcatgg ttcgtgatca ttgggtatag ttaaattaag aaaactgatt gataaaaata
     8101 gaagttgaag gagataagaa atgaaagagt ggttagatcg tgccttttta ccaatgataa
     8161 catctgttgt gaatcttaga cccttaactg ctttgcgtaa tggaatgact tacacgatcc
     8221 caataattat tgttggctcg ctgtttttct tatttgctca ttttcctgtg gattacatcg
     8281 ctcagtggat agacaaaaca ggattttcta tgtattttac acaagtatac caggctacat
     8341 ttgatgtgat agccttttgg atcgtttttg ccattgcata cgcttatgca aaagaagaag
     8401 acatcgatcg cttaccagtc ggcataacag ccttgtctgc ttatctactg cttattcagc
     8461 cactaaatac tcagatagat actgtctgga caggtgctga agggatacta ggagcagtta
     8521 caactgggct catcatcgga tggggctatg cacgtttagt aagacttgcg aaagggtgga
     8581 agcaaagaga gaagatacct gaaaatgttt ggcagtcttt tacttcattg attccaatca
     8641 ttgttatagt cacttttacg cttatcggtt cagcggtttt tcaacagttg ttcagaatga
     8701 ctgttgttca aggagtatgg acatatgtcc agcttcccat tcaatcgttc atagacacgt
     8761 tgtttggtgt gcttttatta ggtttttttg ttccgttttt atggttattt ggtcttcatg
     8821 gatctgcgat ggtcaatggg ttggttagtc ccgtcttgca agcgaattca ttagcgaatg
     8881 cagaaatctt agcctcagga caagagttga cggtggcaaa tggcggacat atcgttactc
     8941 agcaatttct cgatcagttc atgacggtta cgggtgctgg attgacgtta ggggctgtat
     9001 tttttatgac ggtttttgcg aaatcgaaga aatacagaga attaggaaat cttgctcttt
     9061 taccagcctt tttcaacatc aatgaatcaa ttattttttc cacaccgatc gtgatgaacc
     9121 cgatgatggc tgttcctttt attttcgcac cggtcgtttc aggattgatt acctattccg
     9181 ctttatattt tggattcgtt cctttattta cagcagtcca agtcccttgg acaacaccgc
     9241 cgatcctctc gggtttctta gtaggcggag tgcctgcagc gattttacaa ggtatcgtgt
     9301 tgtcaattag ttttttcatt tatttcccat ttttgaaaaa aatagattct gcaaactgca
     9361 aaaaggaaag acagacaaaa aatgatggag cagcagaaaa gatgaacgac taaaaaacaa
     9421 aaatactcct gtcgctttag attgggaaaa tcaccaatct aggatgacag gagtatttat
     9481 agtcatgttt atactagccc tttttggaca gctaattgaa caagaacaac taatgtgttc
     9541 attcctacgt gtgtgatcat cgatgtccag atccgaccag ttgctttgta ctctaggctg
     9601 aagaagaaac ctaggaaaaa gtagattagc agatgaccat cattatgagc aaacgcaaac
     9661 agcaaagagc tgatcactgc tccgacccaa aaatttgaat atcgactgat gatccccagt
     9721 atactgcggc ggaatacgaa ctcttccatg atgggtccag caacagttgt cgccaaaata
     9781 aaagcgggtg cttccatgat catctggatg atattttgtg tattctcgga aggggttgct
     9841 ttgccaaaca atacagattc taacatgaca gcgatgcttt gcagaatcaa tgcgacaaag
     9901 attccaacca atccataaat aacaatcttt ggagcagaag ctttttttac cgctgattcg
     9961 atcgctaagg gttcacgttg cttaaaataa aaaatagcta ggacaacggc gcctagtata
    10021 tacatgactg cagttgctgt gatcaattca gacgtagatt ttacaagtcc tatcgaagct
    10081 aggatcaagg gtgagataaa aattagacca tagcaaaaaa tgctgaggaa gctatatttt
    10141 tttaaagaca tgtaattcct ccttttaagg gataacaagc atgcaaggca agcttatatc
    10201 gattgatttc aattatatca taatttcaat aagcagctgt cagaataaaa tttcttttct
    10261 ttgatttaaa agcttgcaaa aaagagggag aatgagtatt attaaaaatg taggttagca
    10321 ctcgaaggtt aagagtgcta acagattaaa aaaagagtta tcggagggat ttatcgtgtt
    10381 aaaaccatta ggtgatcgcg tcattatcga agtcgcaaaa gaagaagaaa aaactgtcgg
    10441 aggaatcgtt ttagcttctg ctgctaaaga gaaaccccaa actgggacag ttgttgcagt
    10501 cggtgaaggc cgtttgttag aaaacggtga aaaagttcct gccgctgtaa aagcaggcga
    10561 ccaagttatg ttcgaaaaat acgccggtac agaagtaaaa tacgaaggaa aagaatatct
    10621 gatcgtcgca ggaaaagata tcatggcgat tgttgagtaa atttggaaga taaaaaaata
    10681 atcaaaaata atcaatgagg tgaatcaatc atggcaaaag aattgaaatt tgcagaagac
    10741 gcacgcgcag ctatgttacg cggggtagat aaattagcag atacagtgaa agtaacatta
    10801 ggacctaaag gccgaaatgt cgtactagaa aaatcttacg gctctccatt gatcacaaat
    10861 gatggtgtga cgatcgcaaa agaaatcgaa ttagaagatc attttgaaaa catgggtgca
    10921 aaacttgtat cagaagtagc atcaaaaaca aatgatattg caggagacgg tacaacgaca
    10981 gcaactgttc tgacacaagc aatcgttcgc gaaggtttaa aaaacgtaac tgcaggtgct
    11041 aatcctctag gcattcgtcg cgggatcgaa ttggcaacaa aagcagcagt cgaagaattg
    11101 cataatatct caactgttgt tgattcaaaa gaagccattg cacaagtagc agctgtttct
    11161 tcgggttctg ataaagttgg acatttgatt gctgatgcaa tggaaaaagt tggaaacgac
    11221 ggtgtcatca caatcgaaga atcaaaaggg atcgaaacag aactagatgt tgtagaaggt
    11281 atgcagtttg atcgtggtta cttatcacaa tatatggtaa cagataacga caaaatggaa
    11341 gctgttctag aaaacccata tatcttgatc acagacaaaa aaatctctaa catccaagat
    11401 attctgccat tgttagaaca aatcttgcaa caatcacgtc cattgttgat tattgctgac
    11461 gatgtagatg gtgaagcatt gccaactctt gtattgaaca aaatccgtgg aacattcaac
    11521 gtagtagctg taaaagctcc tggtttcggc gatcgtcgta aagcaatgct tgaagatatc
    11581 gctattttga caggtggtac agtaattact gacgatctag gtttagaatt gaaagatgta
    11641 acaatcgaaa acttaggaaa tgcttctaaa gttgttgtag ataaagacaa tacaacgatc
    11701 gtagaaggtt ctggagaaaa agaagcaatc gaagctcgtg tgcaattgat caaaaaccaa
    11761 attgctgaaa caacttctga ttttgaccgc gaaaaattac aagaacgctt agctaaatta
    11821 gcaggtggtg tagctgttgt taaagttggt gcagctactg aaacagaatt gaaagaatta
    11881 aaattacgca ttgaagatgc attgaatgct acacgtgccg cagtagaaga aggaatggtc
    11941 tcaggtggtg gtacagctct agtgaacgtt atcagcaaag tttctgctgt agaagcagaa
    12001 ggagacgtgg caacaggtat caagatcgtt gttcgtgctt tagaagaacc aattcgtcaa
    12061 atcgctgaaa acgctggtta tgaaggatca gtgattgttg ataaattgaa gaacgtggaa
    12121 ctaggcactg gtttcaatgc tgctactgga gaatgggtaa acatggttga agcaggtatc
    12181 gtagacccaa ctaaagtaac acgttctgcc ttgcaaaatg ccgcttccgt ttctgccttg
    12241 ttattaacga cagaagcagt cgttgcagat aaaccagaac cagcagcgcc agcagctcct
    12301 gcaatggatc catcaatgat gggcggtatg atgtaagaaa aagcaacttg cttatctaca
    12361 actgatcatt agtgaaagac agataaaaag aggctggaac agaagcgttt aactccaaga
    12421 aataagaaga aattcacgga aattgctttt caaatttttg tgaatttcag cttatttccg
    12481 aaggagttgc ttctgcttcc gctgtttata cgtgtttaga gcgtgagaca aaagtgttct
    12541 ttacttttgt cccacgctct tttttgtgtg taattataat gaaaatagtt atttttaata
    12601 gttataatat tttatctatt aaaagtaaat atccattc
//
LOCUS       DAIGTA010000072        11343 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.075, whole genome shotgun sequence.
ACCESSION   DAIGTA010000072 DAIGTA010000000
VERSION     DAIGTA010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.075"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(51..878)
                     /locus_tag="NOB43_002348"
     CDS             complement(51..878)
                     /locus_tag="NOB43_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983183.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKFLQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            1444..2679
                     /locus_tag="NOB43_002349"
     CDS             1444..2679
                     /locus_tag="NOB43_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCI0983184.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(3678..3938)
                     /locus_tag="NOB43_002350"
     CDS             complement(3678..3938)
                     /locus_tag="NOB43_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI0983185.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(3965..5266)
                     /locus_tag="NOB43_002351"
     CDS             complement(3965..5266)
                     /locus_tag="NOB43_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0983186.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            5701..6660
                     /locus_tag="NOB43_002352"
     CDS             5701..6660
                     /locus_tag="NOB43_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0983187.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            complement(6624..7082)
                     /locus_tag="NOB43_002353"
     CDS             complement(6624..7082)
                     /locus_tag="NOB43_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0983188.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLNFVCQIKLDKSSFVT"
     gene            complement(7095..8426)
                     /locus_tag="NOB43_002354"
     CDS             complement(7095..8426)
                     /locus_tag="NOB43_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HCI0983189.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(8437..9879)
                     /locus_tag="NOB43_002355"
     CDS             complement(8437..9879)
                     /locus_tag="NOB43_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0983190.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(9866..10516)
                     /locus_tag="NOB43_002356"
                     /pseudo
     CDS             complement(9866..10516)
                     /locus_tag="NOB43_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
     gene            complement(10535..>11343)
                     /locus_tag="NOB43_002357"
     CDS             complement(10535..>11343)
                     /locus_tag="NOB43_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0983191.1"
                     /translation="KLNHNAVLIDDDGIEKIAMGKGIGFSAKVSKPFDVEDADKLFVL
                     DSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARISSPLDSNIYITLTDHIYFAIQRK
                     REDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHRYQTELGSNEVGFITMHIINAELG
                     EPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLTYHRLMVHIKFLVKRLIYQEETPV
                     ENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQENEIIYLAIHLARIY"
BASE COUNT         3685 a         2290 c         1744 g         3624 t
ORIGIN      
        1 ttttttcgaa taaacggtat tcaaatcaga acactgattt cacaaccact ttatttcagg
       61 tcgttttcaa tcacctttac cgcgtaatca tttccgttga aacgcgctat tttttttgcg
      121 tccatatatc tttctaaata atcatcttct cctaattgct tatggcaaga agcaatttca
      181 taaagcaagt attccaatgc ataagtcgat ttatgtttct tattatactc aatacccttc
      241 tcacataatt ggattgcttt atcataatcc tcgattttac ggtaataggt ggcgatatca
      301 taatatacaa tgcagaccat cagattatca aaatcagtct cactcaatat tttaagtgta
      361 cgctccacat aaactttcgc aaaatctaat tctccttttg acaagtagat cattgccacg
      421 tttgcagctg cttgtaagtg atggatatct gtttcggtcg tttgttccaa cacttgatta
      481 aaataaaata atgctgcatc tggttttttc gcataaagat gatcaagcag tccttgataa
      541 aataaaattt gatttaaaag atcagaatta cttacttttt cctgatcgat cgtttgtaaa
      601 aatttataag attcttggta ttttgataca gaattcaatg attgaatctc atttattttt
      661 ttcctgattt tgtcttcttc tgtttctact aatatatcgg agatctcgac attcagcttt
      721 ttgcaaagcg cacttaagat attgatgcct ggcgacatat tcttgttttc gatattgctg
      781 acagttgctt gttcacaaat gccttctgct aattgtactt gtgttaaccc ctttttcttt
      841 cggtattctt ttagtaatgc tccatctact ttaatcaaaa caatttcctt ccctttaaaa
      901 aattatttct cctttatatc atacacaaaa aaaagttcta aacaaccaaa aatgtttaga
      961 acagaataaa aattttaatt ttaaaataat attcaaatta aacaactggc gtatctgctc
     1021 cttgatttct ttttgtgtta tctgaataat tatcgtttac agttataaca catagtgaaa
     1081 attgtcatgg cgagaaagtc taagaatatt tttaaacata actatttctt tcttacgtgt
     1141 ataatgacga cagcacacct atcaattaat ataattattt tattttttta tgttctcatg
     1201 tttattttta atgacacaac ttctcgtatt tatctggcac aacatataaa tcgatcaaaa
     1261 aattgttgcg tgtttttttg aaaattggag tttcaacttg attacaaaat ttaaatttag
     1321 aagttgtgaa aacagcgaga gacagtttaa tattcaaaat atacataggc tactcgaacg
     1381 ctgtgttttt tagtatacta gtaagaaacg aagggataga ctcattccaa taaggaggat
     1441 ttcatgaaga caattctttt tgctcctgca gtattcaatt tagctgagac aacacgaatg
     1501 attgaggttg ccaaagctat gaaagaccgt tattactgtg tattctttgg cttttctaaa
     1561 acttttgctc ctttgatcac agaaagtggc tttgagtatc atttactagc gccgatcctt
     1621 acgaaaaaac aagaagaaca aatcataaaa tttgaccagt tgcgtacact taaaaaccct
     1681 tttaccaaag aaatggttgc ctctcgtatc actagtgaac agagtctgat tgctaagttt
     1741 gagcctcgac tgattgtgac aggttcgaat gtgacaattt ttttatcggc ccgcaataaa
     1801 aagattcctt tagtatatgt taaaccctat gctttgagtg aacctttttt tcaatcagag
     1861 catgcgctga tgccccacga gttacgtttc ttcggccctt taagcaatcc cctttggcac
     1921 tggacaaaaa agcgtatagt aaatacccga tggatcccca atgccttcaa acacgctgca
     1981 caaaaagaaa tgcttccttt accaaaaaca agtttacaaa tgatggatgc tgatctaaat
     2041 ctcatcacaa cgcctaaact atttttggaa gaagaacagc tgccggaaaa ttatcgaatc
     2101 gttggtccaa tttttgctaa gctcagtact tccttgcctg aagaagtgct aacttttata
     2161 cagcgaaagc aacaagaaag aaaacgtatt atctatttcg caatgggtag ttcaggcaat
     2221 ccgcgtatgt tacgcaaaat tttgttcttc ttacaaaaac aaccggatct agcggttatt
     2281 gcacctattg actatctgct tgatgacatt caatctgact cagaagatct tttaataaca
     2341 gaatatctgt ctagtcatct tttgcatgaa ttcattgatt tttcttttat ccacggcggg
     2401 gaagggaccg tccaaactgc ctgtgaatcc ggcaaaccgt ttatcggtgt ggggatgcaa
     2461 tttgagcaaa gctgtaatat tgactattgt gtaaaatacg gaaacgcaat cgccctcaca
     2521 aaaccagtga ctgaaagaaa actgcagatt gctctgcgcg aagtttcttc acccaagatt
     2581 cgtcagcagg cacgcacgct gcaagccgtt tttccaataa atggtccaca acaagcaatt
     2641 caagaaatcg aaaccttcct gagcaaccac ccaatatagt ttcaagtaga aaaagctttt
     2701 ttaatagaga ctcatcagta atttcgctat tcgagaccca gacagtgaaa atacaaaaaa
     2761 agtaaatagt ggattgaaaa gttagagtta cttaaattac ggtgtctaaa aaacacaaaa
     2821 tcatccttaa aataaaagat ctgacgctat ccaaatgagc ataggtagcg tctgccattt
     2881 attcttagtc aaattctttg acacctttct ctggttggat catctcaacg tttcttcaaa
     2941 agaaagacca taataattag gcaaatacat tttcttaaaa tgtgtcatat agatctagaa
     3001 gcatcgcttt gtagagattt gtgccgctag tcccctcaac aattactaaa tcaaatgtag
     3061 gatttaccac tttatctttg ataatcaacc tccctcttct gttgagacaa tgatctcgca
     3121 atccgatgca tactcctata taaactgcca gcaatcccca catattgagt agatcatgtc
     3181 agaatgttct atgtcgtcag caacgataca ctaaaagtca cgttcaccat gactgattgc
     3241 tattcccagc acaattattt ctatacacgt ttcatgattt gaataaacac tcacatcata
     3301 catattacca ttcatacacc atactgcagc ccctactata tggttgtaag ctcccaaatc
     3361 tatatttgac ttgatcactt tggtagtaga tctactaatt ctaaatccat tgctgataaa
     3421 atttccattt tttcctcctt ctttctgcca aaacagttaa aacaataata atctttatgt
     3481 aaaaaagggc tgtgacaaaa gccttgtcac agtcccatat tccgaataaa cggtggtcaa
     3541 aagcttgcat ctgcggtaat aagttcaacc aaacgaaaaa taagccaaca tttcacaaaa
     3601 atttaagaag caattttcgt aaatttcttc ttatttcttg aagctaacca cttctgttac
     3661 aaccactttt agaacattta aagcttcgat gtgacaaacc atctatgctg ctcgatcata
     3721 aaattgatag caaaaattcc acaaagtaca tatgtccccc atgaaaacaa aacattcata
     3781 tgcggtacaa tgatctttgg aagaatcacg atcaaaaatg atgccagtgc ccaaatccat
     3841 cgattgattt gaatatgata tgtagctagc atattcaata taaggtgact agccgttaat
     3901 aaaaagataa aaacaaaaaa taaaatcagc caatacattg tttcccacct tctaaaaacc
     3961 aaacttagac agtctggact tcgttttctc cacgactttg ttcatctgac agcatctttt
     4021 tatcataagc ttttacaaat ggataataga taataaatgc tatcaatgtg ttgatcatga
     4081 tcaagataac aacacgccag tcatttcctg ctgaaagata accgccgatt ggagctggta
     4141 atgtccatgt tggcaaaaca gtaaatctat tgaccatttc taatttgact gcaaaataac
     4201 tgataatagt caaaactaaa ggaactaagt tgaacgggat gaacatgtaa ggattcaaca
     4261 tcataggagc tccaaaaatt atgggctcat tgatattgaa gataccagga ataatagaaa
     4321 aacgaccaac ctctttcaag aattttgatt tacagaagaa tataaacaaa acagatacca
     4381 cgatcgttgc tcctgcacca ccaattgtta ccgtccattg ataaaactgt tcaggagcga
     4441 tatagggtaa ttgggtggca gctgtaccat ctgccaatgc ctttgcattc tcatccaaca
     4501 tgatcagcca cattggacga acaacagccc ctacaatact catgccatgg ataccaaatg
     4561 accacaacaa atggatcaaa aacattggta gtaaaacacc aagcaaatta ttccctaaaa
     4621 tattggttaa aggctcgaat aacgataata aggcagcgtt tacatcaaag cccgcgacgc
     4681 ttcgaatcag ccaagtaatt gttaaaatga ctgcacctgg aatcaatgcc tcaaaactac
     4741 gggcaacagc aggtggcact tgttctggca ttttgatagt aatatttcga tttttaaaga
     4801 aacgatatac ttccactgca aaaatcatag ataagatccc cgcaaacatc ccagatgctc
     4861 ccaaagaact cataggtaag acccagccaa gaggtgcctc ttcaggagtt aaaacgttta
     4921 caggaacttg taacataaag aacgttccta aagataatat accacctgtc acactatcta
     4981 atccatatga tttagctaga tccgaaccca taacaaaagt tgcataaata gccatcaatc
     5041 ccatcgtcat cctaaagggt aaaacaatcg ttgccgaata aggggcaata aattcattcc
     5101 atccaggaaa cggtaaattg ataaagacca taaaaaatgt cccaatcaaa atcaatgaca
     5161 atgttgaaac aaccccatta cgaattgcta ataaatgacg ctgtgtacca atttttgcca
     5221 ttggtgggac aagtttctct tcgacccatt tcatcagctt ttccactaaa accactcctt
     5281 ttcaataaaa tatgaaccat tcattgcatg acaacgcaaa gaatgttcat aactaattat
     5341 ataattaaga aattttattt caatatattc tcttaaataa tcaaatttat ttttaagaat
     5401 cctgaaaata agttttctaa atcataggag caacaaaaaa attcgataat taacaaaaat
     5461 caaaatgatt aaatctagtg attgaaacat atcatttcaa aaaaattttg taaattcacc
     5521 cataaatatc accctattta acttttttca tcgtacacta aaattcaaaa caactatctt
     5581 taatctttac ttcttggttt tgttttcgcc gattgtaaaa ttaagctaga caactaaaaa
     5641 aagtcatttg tgctacactc aaaatagttc cgacgaaaga attataagga gtgagtacaa
     5701 atgacctata accatcttac accaactgaa ctcgtaatga tagaagctta tttcaatcaa
     5761 tcacaacctg tttcaaaagt agccaatctg ttacaacgtt ctcgacaaac tatttataag
     5821 gtctatcgtt ttcttaaatc tggtggaagc gcaatgagct actataaaca atataagaaa
     5881 aacaaacgta actgcggaag acatccgatt gttttacctg atgagcaaca ggaatacatt
     5941 caaaaaaagg ttgttcaagg gtgggctcct gatgtcctta ttggtcgagc agagtttcct
     6001 attgcttgtt cggtacgcac actgtatcga atgtttaaag ataaaacctt tgacactcac
     6061 gatttaccaa tgaagggaaa aagaaaacca aacggtcata aagaaaaaag aggaaaacaa
     6121 gggtttcgcc ggtcaatccg agacagaaag acagactata cccagtttga tcatgaattt
     6181 ggtcacctgg aaggtgacac tatcgtgggt ggaaaacata aaagcgcggt catcacatta
     6241 gttgaacggc tatctaaagt catcattacc ttgaaacccg aaggcagaca ggctaaagac
     6301 attgaaaata ggctgaatca atggtttcgt tgtgtcccaa aaaacttatt taaatccatc
     6361 acatttgatt gtggaaaaga attctcaaat tggaaaaaga ttagtaatac caacgatatt
     6421 tcaatttatt ttgcggatcc aggaacacct tctcaacgag gattgaatga acattcaaat
     6481 ggcttattac gtaaagatgg tttgtataaa gctatggatt ttaatggtgt atctgaaacc
     6541 tttatccaat cggtggcatc gaaacgaaat catattccta gaaaatcatt acactatcgg
     6601 acaccaatgg aagtattttt gagttacgtc acaaaagatg atttgtctaa cttaatttga
     6661 caaacgaaat ttaataaatt tccttcaaaa atgcctggag aaactacaat gatcaccgta
     6721 tctttttgtg cttgctccaa cttcttcaaa tctataatag ctaacagtgt cccttctttt
     6781 acctcctggt tactttcaac ccgtatctga aacggacttc cttcgagttc aactgtatct
     6841 aaacccatat ggatcagtat ttttctgcca gattcacttt cgatcgttat ggcatgtcgg
     6901 gtaggaaata tattatcgat tattccttta actggcgcat ggatatatcc atcatgattc
     6961 gttatagcgt atccaactcc tatcattttt gaagaaaaga cctcgtcttt tactgctgtt
     7021 aatggaataa tttgaccact agctacagct tttagaatgt ttcttgtttt aaagaaatgc
     7081 actttttatc acctctactt taatgctggc caatattttt tgtttacttt gatcatttca
     7141 tctagtattt tttttgcgac tctggcattt ggtacggttt gattcaatgt aaatgcttgt
     7201 aaagcttttt gataagaacc ttcaaagtaa gcatctacta gtaacttctc tactgcaact
     7261 tgtgcctcca tcaatccttt atgaaaatca ctgattggtt ttcttagtgt aattggctcc
     7321 acaccagttg caccaacata tgccggtatt tcaacaactg catctgaccg tagattcgga
     7381 atcgcccctt gattaggaac gattagcata aagcgacgac gatcatcatt caacaaggaa
     7441 atagctatat cgacgatata ttgtccatgc tccccaaaat taaagttcaa tacttcttcc
     7501 acaataccgc ggcgtatttt atcagccatt tctttggtat ttttctctcg tccatccatg
     7561 accatattag cacgtgtata ctctttgtca gtatgctcaa cgaccatatc aggatataag
     7621 taatactcta agtaattatt cgggatatta cttggaaaat ttttcgtgat gactgacatc
     7681 atttgaaagg ttttttgcca agttttatct cctatattaa aatcggcgac ttgcatttct
     7741 tttgttatta gtttttcaat aatctctggc ataatttctc gttgcaattc tttatcataa
     7801 atcgatgtat accagccaaa gtggtttaaa ccataatacg taacgatcca attcttacga
     7861 tcataaccgt aattcactgc aatcgtttct tcaattgaaa tagtcatatc acaggcatta
     7921 atcattttta cattcggata tttacgacga acagcttcag aaacgatcga ctctggattt
     7981 gtataattca aaatccatgc tttgggggca tagtcttgta tatgatcgac aatttccaat
     8041 aaacctttga ttgagcgcat cccataagca aatcctccga gtccacacgt ttcttgtcct
     8101 actaatccat gtttaagtgg aatcttttcg tccttttctc gcatctccaa tcctccaaca
     8161 cgaatttgtg agaaaacaaa atcgcatcct gtaaaagcaa gctttggatc atccgttgca
     8221 cgaatgcgaa tatttgaaaa accttttctt ttcagcataa atttaacaat caagtacata
     8281 tccatatttc tttcttcatc aatatcatat aaacgtattt cagataatgg caaccgtttt
     8341 tcattgttca aaatggcttg aacgattcct ggtgtatacg tactcccgcc tccagctata
     8401 gtgataatct gttttttcat catcatcttt tcctttctat tcttctaata atttattgaa
     8461 ttctgccata acataagtca cttctaagcc gatgataatt tgataatttt tttcagttgg
     8521 tttaatgatc ccgcttatcc ctaattgctt gattcgctgt tcctcgacca tggtgggatc
     8581 cactacctct acccgtaggc gtgtattaca actatagaca tccaggatat tggcttttcc
     8641 tccaaacgct tgtagcattt ttgttgccat atattcataa tttttacttg ctaaccctaa
     8701 ctctgtttct tctaaggtta cttcattgcc aaactctgcc ttagcttcac gtcctaatgt
     8761 ctgaatgttt ctcttattga tcaaataata aaaagtaacg taatacaagg caaaaaagaa
     8821 aattccgatt ggaagaatca aaatagcatt ggtagcgatt cgaaaattga tgagataatc
     8881 aacaatacat gctccgaatg taaaaccaat tcgtatattg aataagtaac agacaatccc
     8941 tgctaaaccg gcaaaaagtg catggatcac gtacaacata ggagaaagaa acatgaaact
     9001 aaattcaaca ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc ttcccatgat
     9061 tcctttgacc atctctttat tttctttata agctgcttta tagatagcta gacatatagc
     9121 tggtatacca aacatcatta ctacaaaaaa aactgataaa aacagtccag cctgaggatc
     9181 tccgttgata aagcgtgtca tctctcctct gaaaacttcc ttgctaggag atgtatagct
     9241 tcctaaatcg taataaatat acgtattcaa cacatggtgc agtccaaagg ggatcagcaa
     9301 acgattcaaa aacataaata tccccacacc taatgctccc atatcaacga gcagttttgc
     9361 aaaattatca atcccaattt ggatgagcgg ccagataaag cccaaaaaaa cagctgcgat
     9421 tgtttgtaga atcatcacca tagtcaatgg gaatttttcg cccgcaaaat aagaaaaaac
     9481 tactggtaat ttttgttctt taaagcgatt atacgtccat gccgctacta aaccggaaat
     9541 aattccacca aaaatcccca tattcacttc tgggtccata atttctaagc cttttttcaa
     9601 ggtagcaatc gctaaaaaac cagtaagtgc aggtattcct ttgtccttat ttttgacaaa
     9661 accgattgca actcctatag caaataagat atccaagttt ccaaaaacgg catttccagc
     9721 tgcaccaatt actgggatgt tcagcatatc gtcagctgat aaacgcatga tcaatcccgc
     9781 taatggcatc gctgcaactg gaagtagcat cgctcttcca agcttctgca catttgattt
     9841 aacattcatt tttattcctc ctctattaaa tatcctcata tgttactaac tcaatcaaag
     9901 gatcattttt cactttttga gcaaatgctg aatgaattaa aaattcgact tggtgggtac
     9961 gaggatacac aaaacttgaa ccatttaaca attcctgatc caaatacgct gcgtgacaca
    10021 tgacttcgat cgttttatct tctctcaata tcatgagtaa acttgccaaa tattcttcca
    10081 cactcgtatt gatttgtcgt tttttttcat cagtttctcc tacgacatcg aaacaaggct
    10141 caaaataatc gacatgacga acttcatctt ttcgttcaaa gttgctccga accggcaaat
    10201 catatttttt tgctaatgta acaactacct cctgattttc atccaaagta tgagtatgat
    10261 gatgactgtc taaatgagtt ggtatgatcc ccgcatgata aattttttga atctgagcat
    10321 tccattcctg atacagttga tctttgtcaa tgttaaatgg atgctgataa taagataagg
    10381 atctgaactc tccgctttcg ataagagtat cgacagtttt gaggagtggt ttgccacacg
    10441 tcaatgttaa atggactcct acacctagcc taggcatttc ctttcttagt ttcacagcat
    10501 gctcgaaacc cggcatgata gttacgccct tattttaata gattcttgct agatgaattg
    10561 ccaaatagat gatttcattt tcttgaatgg caagttgaaa ttgctgttcg atgatatctt
    10621 taatctttag tgctgtacaa tacgctttgc tatgtttaaa tgtttcagta aaaaaaccaa
    10681 tattttctac tggcgtttct tcctgataaa tcaagcgttt aaccaggaat ttgatatgaa
    10741 ccattaagcg atgataagtc agtgattctt tatcataaac gtttgaatag gatttttcta
    10801 gatgggacaa aatcgtggtc gtcatttcta ctatttttaa gctctttaaa ctattaggct
    10861 ctcctagctc agcattaatg atatgcatag tgatgaatcc tacttcattt gaccctaact
    10921 cggtttgata tcgatgattg attcgctcga ccacttctac tgctatatca tattcatttg
    10981 gataaaggaa tctcatttct ggcaacataa ttgctgtgac atctctatct tctctttttc
    11041 gttgaatagc aaaataaata tgatctgtca atgtaatata gatatttgaa tctaatggag
    11101 aggagatcct agctgttatc agttcaatca cttcttccgc aaaatccata aattcgattg
    11161 gaatctgcga gactatctca ctgaatcgtt tgatcttttc tttagaatct aatacaaata
    11221 atttgtcagc atcctcaaca tcaaatggct tactcacttt agcagaaaag ccaatccctt
    11281 tccccatcgc aattttttct attccatcgt catcgatcaa tacagcatta tgattcagct
    11341 ttt
//
LOCUS       DAIGTA010000073        11254 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.076, whole genome shotgun sequence.
ACCESSION   DAIGTA010000073 DAIGTA010000000
VERSION     DAIGTA010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.076"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="NOB43_002358"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="NOB43_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCI0983192.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="NOB43_002359"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="NOB43_002359"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCI0983193.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="NOB43_002360"
     CDS             complement(2169..2906)
                     /locus_tag="NOB43_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI0983194.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="NOB43_002361"
     CDS             complement(2997..3524)
                     /locus_tag="NOB43_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983195.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="NOB43_002362"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="NOB43_002362"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCI0983196.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="NOB43_002363"
     CDS             complement(4401..4886)
                     /locus_tag="NOB43_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCI0983197.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="NOB43_002364"
     CDS             complement(5039..5236)
                     /locus_tag="NOB43_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983198.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="NOB43_002365"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="NOB43_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HCI0983199.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="NOB43_002366"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="NOB43_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HCI0983200.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="NOB43_002367"
     CDS             9211..9423
                     /locus_tag="NOB43_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HCI0983201.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="NOB43_002368"
     CDS             9425..11104
                     /locus_tag="NOB43_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI0983202.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3589 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaat
//
LOCUS       DAIGTA010000074        10799 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.077, whole genome shotgun sequence.
ACCESSION   DAIGTA010000074 DAIGTA010000000
VERSION     DAIGTA010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.077"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            185..1183
                     /locus_tag="NOB43_002369"
     CDS             185..1183
                     /locus_tag="NOB43_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0983203.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="NOB43_002370"
     CDS             1295..1804
                     /locus_tag="NOB43_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCI0983204.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="NOB43_002371"
     CDS             complement(1833..2492)
                     /locus_tag="NOB43_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HCI0983205.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="NOB43_002372"
     CDS             complement(2494..3258)
                     /locus_tag="NOB43_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HCI0983206.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="NOB43_002373"
     CDS             complement(3266..3943)
                     /locus_tag="NOB43_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HCI0983207.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="NOB43_002374"
     CDS             complement(3980..5365)
                     /locus_tag="NOB43_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI0983208.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="NOB43_002375"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="NOB43_002375"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="NOB43_002376"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="NOB43_002376"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCI0983209.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="NOB43_002377"
     CDS             6304..7161
                     /locus_tag="NOB43_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983210.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="NOB43_002378"
     CDS             complement(7242..7577)
                     /locus_tag="NOB43_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983211.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="NOB43_002379"
     CDS             complement(7644..9014)
                     /locus_tag="NOB43_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HCI0983212.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9310)
                     /locus_tag="NOB43_002380"
     CDS             complement(9092..9310)
                     /locus_tag="NOB43_002380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983213.1"
                     /translation="MDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQD
                     FLEMMNAVWDKNEVTDEYLENILKEQSP"
     gene            complement(9313..9624)
                     /locus_tag="NOB43_002381"
     CDS             complement(9313..9624)
                     /locus_tag="NOB43_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0983214.1"
                     /translation="MGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYPI
                     YTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFLSMKVFVKSLQNL
                     I"
     gene            9936..>10799
                     /locus_tag="NOB43_002382"
     CDS             9936..>10799
                     /locus_tag="NOB43_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983215.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFL"
BASE COUNT         3284 a         2185 c         1753 g         3577 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgcttttg gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcactatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaatctttc aataagtaga caatgcttaa aacatcatcg gaactgcatt cagctaagta
     9421 gttttcaaaa taaacagtga tttcttctaa tatcttctct tttaacccgc tgattgattt
     9481 gaaatgtgta taaatcgggt atgtagaaca accgcagaac tctgctaact ctcttgcagt
     9541 aattgacttc attccatatt cttccacgta taccatactt ttgaacagca aatattcttt
     9601 actataattt gttactctcc ccatcattct tacctccgtc tcttttcatc tacccataaa
     9661 taaataacat aaataattct aaaaatatta ttgataatta tcaaaacata tttagttata
     9721 tccattaaaa atcaattttt ccgccttaaa aacaagaata tcttgacaaa ataccctagg
     9781 aaataaacaa tagaataaac aaggtaacaa aaaaattaaa taacgttata taaaaaagaa
     9841 ggcgacactc tgtgagaata acacagactg aaatgacttt ccactcacag tttttgtcta
     9901 actatataca aaaacagaat aaaaaggagg tatttatgct aattgaagca agaaaaaaag
     9961 agttacttgt tctacaaatg gtcattcaaa aaaataattg ttctttacaa gaattatcca
    10021 atgacttaca tattccaaaa cggacaatca aagaactgat ccgaaaaata aatgtatcac
    10081 tcaagcaatt tttattgatt gatgaattta tttattctaa tcataaagga gagatccaaa
    10141 ccaaagaaac cgatcaaact aaaaagttag ctgttttttc taagttaaaa ttatgctacc
    10201 taaaagaatc caatcgtttt aactatttga tgttactaat caattatcca caaactgctg
    10261 taccaaaaaa atatttactt gaacaacttt atatatcgcc ctcctatctc gaaaaactga
    10321 caaaacagct caatcattcc ttaaaaaaat tccatttacg gatcctatct gtaaaaaatt
    10381 gctgtactct tgaaggaaat gagttatcta tccgtctcta tctttacttt tttctttcag
    10441 atacatttgg aggtaacgat tggccatttt cctcacttga attaaatgca ctaaaaatga
    10501 acagtacaga tgagcaaata gaaaaaattt caaaacaaga aaaaaatatc tacttgctgt
    10561 taactttatt catattacga aacaaacaac aggcatattt tccaaaaact tcttctgaaa
    10621 tcactgaatt gatggactta ttgcagcata cacatgatta ttcagaatac tttacttctt
    10681 tttcagtgag tcgcccttgt gaagagacag aaacagagag agcctacttt aattattttt
    10741 tctattgttt ttttccaaat caaatctctt ttcgacaaaa acaggagatt ggtttttta
//
LOCUS       DAIGTA010000075        10590 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.078, whole genome shotgun sequence.
ACCESSION   DAIGTA010000075 DAIGTA010000000
VERSION     DAIGTA010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.078"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            108..311
                     /locus_tag="NOB43_002383"
     CDS             108..311
                     /locus_tag="NOB43_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI0983216.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(412..1074)
                     /locus_tag="NOB43_002384"
     CDS             complement(412..1074)
                     /locus_tag="NOB43_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983217.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(1087..2589)
                     /locus_tag="NOB43_002385"
     CDS             complement(1087..2589)
                     /locus_tag="NOB43_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983218.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            3137..4816
                     /locus_tag="NOB43_002386"
     CDS             3137..4816
                     /locus_tag="NOB43_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI0983219.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            4943..5422
                     /locus_tag="NOB43_002387"
     CDS             4943..5422
                     /locus_tag="NOB43_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HCI0983220.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            5641..6321
                     /locus_tag="NOB43_002388"
     CDS             5641..6321
                     /locus_tag="NOB43_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCI0983221.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            6329..7660
                     /locus_tag="NOB43_002389"
     CDS             6329..7660
                     /locus_tag="NOB43_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0983222.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            7675..8637
                     /locus_tag="NOB43_002390"
     CDS             7675..8637
                     /locus_tag="NOB43_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HCI0983223.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGSIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            8748..9086
                     /locus_tag="NOB43_002391"
     CDS             8748..9086
                     /locus_tag="NOB43_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HCI0983224.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            9165..9872
                     /locus_tag="NOB43_002392"
     CDS             9165..9872
                     /locus_tag="NOB43_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HCI0983225.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(9975..>10590)
                     /locus_tag="NOB43_002393"
     CDS             complement(9975..>10590)
                     /locus_tag="NOB43_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HCI0983226.1"
                     /translation="STSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVF
                     FELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLI
                     QHLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQH
                     EKISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3392 a         1882 c         2250 g         3066 t
ORIGIN      
        1 acagctctaa ctatcttttt tagaaaacga gcgttctgtt tgtctgtatc tgttgttgat
       61 gttaccctga aggtagatca ataaacaaac taagaggagg aagcacaatg gcagatttaa
      121 aaggacgttc taaagatatg aaagataaag tagtcggtga aggaaaagaa gcatacggca
      181 aagcaacaga cgacaagagc aaagaaacag aagggaaagc acaatcacta ggtgctgaca
      241 tcaaagaaaa agctcgaaat ttaggcgacg aagtcaaaga caagttttct cgaaaagacg
      301 aaaaaaaata aaaaccactt attactaatt gaatcaagca aataaaaaat ccgaaccata
      361 tctgcgagac agatatggtt cggatttttt atttgatcat tatcctgttt tttaaacttc
      421 gattttttga aattttttat tttttagttc aaagacttca tcacagcttt ttgctacttc
      481 aatctcatga gtcacgatga taatacagcg attttgttca tgggcgattt cttggaaaag
      541 tttgacgata tcttgtgaag ttgtttcatc tagatttcca gtaggctcat ccgctacgat
      601 tagttgatgt tcacagcaga tagcacgaac gatagcgact cgctgctgct gacctcccga
      661 aagtttggtc acctgttttt ttgctaatat ttcatcaatt cctacacgag ccagtcgatc
      721 taaagcaact tgtcgataat tctcttgctt ggtcttagtg atttccattg ctgctatgac
      781 gttgtctaga gccgataaat aaggaagcaa gttgtaagct tggaaaataa tcgagacatc
      841 atttttacga taacttctta acccgatttt gttcagtgaa cgatcttgat agtatacctt
      901 tccttctttt ggtgcatcta gtccagaaat aagcgaaaga aaagtcgttt ttccagaacc
      961 acttgctcct aaaatagcgt acatttttcc agcttcgaaa ttcagttcta catctttata
     1021 aagcgcatct tgcggatctt gataccaaaa tcccaattgt tctgtccgta acatcaaatt
     1081 cctcctttag tttaatagga tttttcttgg gtttaatctt aatatcccta tagaagctaa
     1141 aaagacagaa aacagactga ttccaaatgc tactccggct aatagtccca attgtgcagg
     1201 tttgacattg atttccaatt cgctgacttg atcagaaaca gcaaatggat tattcgtggt
     1261 tccttgttga ccatcgcgtt gaccgccttg ttcttgtctg ttacctggca tttgtccacc
     1321 gccaggagct tgctggtttt gtgtcgtggt ttctgtctgt tggtcaagta gctgctgtcc
     1381 cacggcattc gcgacgacgt ttccgctaag cgaagcaact cctaatgcaa gaatcataca
     1441 aatagccact tcggtaaaca attggagaat gattttactt ctggattctc ctaaagatag
     1501 caagacgcct aactcatgcc gacgctcccg aatggtaatc ataatgatca gagtaagtat
     1561 gataataccg gctacagcca ctagtaaaac aacattttta gaaaaacttg ccacgttgtt
     1621 taaaggttcc aacattgact gatacatgga atcatttgat tgtaagctaa atgtatctgt
     1681 gtcgatcagc ttctcagctt ctttgagaaa ctcatccatt ttatctggat cagatagagt
     1741 gtaaatagca gaatctatcg tgttatcgtc agatgtccca tttagttcat ttgcaaaagt
     1801 gtaagaagtg taaagtgtat tcgacggatt catgaagttg aatttcatac ccatactgcc
     1861 gcttgtttcg ctggattcat aaattccttt gatcgtcatt tcataagtgg tatcttcatc
     1921 ttcagtactc gtgattgtga aagtatctcc gactgccagg tcatttgttt ctgctagagt
     1981 agaatcaatg actacattgt ttgtgccttt gtcgctgtca tctattcctt caccatccgt
     2041 gatttttgct gttccatcag aaaaattact attttgtgca gttgctgaca caccactgat
     2101 ttgaaagtct gcttgagtca tttgcggatt cccgcccatt cctccagcag gttcaccgcc
     2161 tgcatcagta gtttctgaac tgtcttcact tgaatcagaa ctagtgatgg cagttattcc
     2221 atcttttgcc atagctgagg cggaactttc aaaggaataa ctctttacat tatctaattc
     2281 agctattttt tccgcgtccg ttaaggaaac tggtgtaaga gaaaaactgc ctggatctgg
     2341 acgttcttca gtggtagaac cgcttgaaga agtttgttcc tgttttttaa atgaagcttc
     2401 tcgattggca cttaaagtca ctgttgctcc aacttctttt tgtgcttgat tcgctgcttc
     2461 ttctgcagcg cttcgaatcg tgaggccagc tagcacaaaa ataagaatgg ctgtgaacac
     2521 ggcaaacaat aacaatgaac gtccccattt tacttttgta cttttccatg cacgtttcat
     2581 aaaattcata ttttgcatcc ctcctagtag atgcatttga taatagacaa cctatcttaa
     2641 agctagctta aatcttatgc tgtttgcaca ccatcaacat gaggttctgt atatataaaa
     2701 agtcactata gttattgcaa aaaatgtggt aaaatgaaaa aagtatgttt caaaccgacg
     2761 aagaagaaat gaaagaggaa tagcaaaaga aatcctagat gctacagagg gatttttacg
     2821 tgcatagttg ttctaacaat tgctgatact agcgatttag tttatttgtt gtataataat
     2881 ggggaacagc tgaatactta tataagtatt ctggctatag cgtttcgcaa aagatccatt
     2941 ttgttaatga agtatatcca aaataaaatg cccatccaac tgtcagaacg cggatgtgct
     3001 ggtaattttc ctgctgattc tccataagtt gagaaatagt gattttgcat atgcttcatt
     3061 ggaatggctc atatatttag ataaagaaga aaatcgacat ctttaaactt ggatgtcata
     3121 agaagaggtg aagtttgtga gtaccattaa aattatccca ttaggcggcg ttcgtgaaaa
     3181 tggaaaaaac atgtatgtcg cagaagtggg cgaggatatt tttattttag attgtgggct
     3241 aaaatatcct gaaaatgagt tgttggggat cgacgtcgta atccctgatt ttacgtattt
     3301 agaagaaaac attgatcgtg tagctggtgt ctttttaaca catggacatg cagatgcgat
     3361 cggggcactt ccttacttgt tgtcaaaaat ttctgtacca gtattcggga cagagttgac
     3421 gatcgagtta gcaaaattga atgtcagtcg taatgaagca gccaaaggat ttaaggattt
     3481 ccatgtggta gatgagcata cagaaataga ctttggtgaa acagtagtga gctttttccg
     3541 taccactcat acgataccag attcagtggg gatcaatctg aaaacaaaag aaggtagtat
     3601 cgtttatacg ggagatttta aatttgacca aacggctatc ccaatgtatc aaacagatta
     3661 tgcacgattg gcggaaatcg gcaaagaagg agtcttagcc ttactaagtg aatcggcaaa
     3721 tgcagaaaat cctcagcctg tagcttctga agcccaaata gcagatgaag tatttgatac
     3781 gatcaaatat tgggaagggc gtatcatcgt cgcttgtgta gcaagtaatt tgcaacgagt
     3841 gcaacaagta ttggatgcag cagaaaaagc acaacgaaaa gttgtcttga ctggtcaaga
     3901 tttcgaacga attattcgca cagcgatgcg tttagaaaaa cttcaattac caagtgaaga
     3961 tctgcttgtt acgttgaaag acatgaaaaa ctatgatcca gaagaactga tcattttaga
     4021 aactggccga atgggtgaac ccatcaagtc tctgcaaaaa atggcaaacg gtacacaccg
     4081 taatgtcaag attgaagaag gagatttggt ttatatcact actacgccaa gcatcgcgat
     4141 ggaaaccatc gtggcgaaaa cggaagatat catttatcga gctggtggaa cagtgaagtt
     4201 gatctctgag aatatgcgcg tttctggcca tgccaatcct aatgacttgc aattaatgat
     4261 caatttgatg aaaccaacat attttgtgcc agttcaagga gagtatcgtg aattagctgc
     4321 tcatgcagat ttggctcatg cagtagggat gccatacaaa aatatctata ttactggacg
     4381 cggagacgtg ctggaatata agaacaagcg tatgagtgtt gcaggaacta caagtgcaga
     4441 aaatgtaatg attgatggat taggcatagg tgatatcgga aacattgttt tacgtgatcg
     4501 aaaaatcttg tcagaagacg ggattttcgt agcggttgtc actatcagtc ggcgagaaaa
     4561 gaaaatcatt tcaaaacctc aaattacttc acggggattc gtttacgtaa aagctagccg
     4621 tgatctgatg aaagaaagca gcaatatgat tgaaacaatc gttgagaaac atttagaaag
     4681 caatgatttt gagtggagca aattaaagca agacatccga gatcaattag gccgttactt
     4741 atttgaacaa acaaaacgcc gcccagtgat cttgccagtc attatggaag ctactcaacg
     4801 tcgaaataaa aaataaacaa aaagagtaag atgaacctct ctatagagtg ctcgtcttgc
     4861 tctttttttg cgaaaaacaa ataatttttg aatacagcat ccctcgcttt ataataaacg
     4921 atagaataaa gggagtgaat caatgatgag tcaaacaaaa gtcgaacgtt atttagaaga
     4981 acaaaagatc agctatcaac cacttgattt tagtcatgtg gtagaagaat ctttcacaga
     5041 agaactacaa aaaagaggga ttgatccagc tttgatatgt aaaactctcg tagtgaaagg
     5101 aaacaaaact ggggtgatca tcgcattgat tcctttgaac gatcacttag attacaaaaa
     5161 aacgagacaa gtgacgaaag atcgtaaagt tggttttcct ggaatggatt ttgtattaat
     5221 gcatacagga tatccccacg gagcaaacac ccctattgga ataaaactcg cacatcctga
     5281 ttattgtttt ttagcagaca gttctttaaa agaaaaagaa gaagtaattg tgtcaagcgg
     5341 tgaaatcggg agaagccttc ggataaaagt agccgattta gaaaagatcg tccatcctat
     5401 ttacgctgat ttaattagtt aagggacgag aagagaagct aagcagagca gagacctcaa
     5461 acttgagatt atatctgctt ggtacttggt gcatcctgta ttatctgtta caattgcttt
     5521 gtacatactg tactatcaat ccaatgaaaa tatatttagc agctatattt tttcattgat
     5581 gtgcaagtga tgaaatcgtt tttaataaaa aagatacaga gaaaacgcga ggtgtaaaat
     5641 atgaaaatta cgtatcatgg acattcctgt ttaacaattg aaatggaaaa tggccaacgc
     5701 gtgatgattg acccgtttat tacaggaaat ccattgacag acttaactgc agaagaagta
     5761 aagacagatt ggttgctgat tactcatggt catagtgacc acataggaga tatgattcct
     5821 attgcaaaag aaaatcaagc cacaattatc agtattgttg agattgctga ttatgcgaac
     5881 agcagaggag tagattcatt cggtatgaat atcggtggaa aacatgcgtt tccattcggc
     5941 gtggtaaaat tcgtacatgc acagcatagt tcaagctatg aagtagacgg tatcgttcag
     6001 tatatgggcg agcctagcgg aattattatt caagcagaag gaaaaacgat ttatcatgca
     6061 ggggatactg cttatttcag tgatctagga ttgcttgcag aagaattcga tattgatgtc
     6121 gctttcttgc cgattggcga taactatacg atggggccag aagatgcagc aaaggctgcg
     6181 caaacaattc gtgccaagaa agtagttcca atccattaca atactttccc tgtcattgaa
     6241 caagatcccg aatcttttgt agagttactg gaagatagtg aaggaaaaat aatgagcgtc
     6301 tcggaaacgc tggaagtgta ggcagaaaat ggcgacaaaa catgatttga ttttagaata
     6361 tattgaaagt ttacctgttg gcaatcgaat ttctgtaaga agcatcgcaa aagaattgaa
     6421 tgtcagtgaa ggaacagcgt accgtgcaat caaagatgca gaaaatgtcg gactagtttc
     6481 aacaattcaa cgagtaggga ccatccgtat cgaacgcaaa ttaaaaaaac atattgaacg
     6541 tttgacattt ggcgaggtcg tcaggatcat tgaaggggac gttttaggcg gggcggcagg
     6601 attagacaag gtcttgaata aattcgtcat cggcgcgatg actaaacatg ccatggaacg
     6661 ctatattacg ccaggatcac taatgatcgt cggcaaccgg gcggaagtcc aaaaattagc
     6721 attggaagat ggcgccgcag tattgatcac aggaggattc aatacgactg ctgagattgc
     6781 aaagctagct gatgatcttg aaatgccgat cttacgcacc tcttatgata catttacagt
     6841 cgcaaccatg atcaaccgag cgttaagcga ccaattgatc aaaaaagata tcatgcttgt
     6901 cagtgatatc tatatgccag ctgaaaagac tcattatttg cagcagacag atacgatttc
     6961 tgattatcag cgtttgtcag aagaaacgca gcattcgcgt tttccagtcg tcaaccgcca
     7021 tcatcgtttg atggggattg ttacggcaaa agatgtttta gggaaatcgc caaaccagat
     7081 catcgatcgg gtgatgacga aagaaccaat cagtgtaaag aaaacaatga gtattgcctc
     7141 tgttagccat caaatgatct gggatgggct agaagtcatg ccggtcgttt ccgatgactt
     7201 gacattggaa ggcttgatta cccggcaaga tgtaatgaaa gcgatgcagc ttgtccagcg
     7261 acaaccgcag attgcagata cgatttcgga tcagatatct ggaaatatcc atacgattga
     7321 tactgaccgt gaaggaaatc gtttggaaaa ccctaagttc aaattcgtag tagcaccaca
     7381 aatggtcaat ggcgttggaa ccatttcttt tggcgtactt agcgaaatca tttctgatgt
     7441 cgcacaaaaa acaatggtga tgaaccaaaa acgaaatatc ttgattgaac aagtgaacct
     7501 acattatttg cggctgatcc aattggaaag cgaattagac attcgtccac gtgtattgga
     7561 aatcggcaga cgttccgcta aactggatat cgaagtgttt attgaaaaca ccatcgtttc
     7621 caaagcaatc gttgtttgtc aagtaatgga acgttcttag aaagcaggag tgaaatgaca
     7681 gtacagcaag aaatagtaga tacaataaaa aaatacgata aaatcattat ccacaggcat
     7741 ttgcgccctg atcctgatgc attaggatca caagtaggat tagccgaact attacgggaa
     7801 agtttcccag aaaaagaaat acgtcaagta ggtgaaacga ttgaagggct tcgcttttta
     7861 gcagaaatgc aagaagttga agatgtcttc taccaaggag cgctagtcat cgtgactgat
     7921 acagctaatt cacccagaat cagtgatcaa agatatcagt tggcagaaaa actgatcaaa
     7981 atcgaccatc atcccaatga tgacccttat ggagatcttg tgtgggtaaa tacaaaagca
     8041 agtagctgta gtgagatgat tgcagaattt gctttgatgt ttcctgaatc tttaaagatg
     8101 aacgttaagg ctgcacggtt actttatgca ggaatcgtcg gagatacagg gcgctttttg
     8161 tatccctcca cgacgtcccg tacattagag attgcttcga tattgagaaa ttatccattt
     8221 gatgcaagtg ctttgaacag agagattgaa caaatgccga tgaaagtcgc taaactttcc
     8281 ggttatcttt atcaaaatat ccaggtggat gaaaatggtg caggaagaat aatccttccg
     8341 caagaaattc ttgataaata tggaatcgat gattcagaga cagcttcgat cgtttcactt
     8401 cctggagtga ttgacgaagt gctggcttgg gggatttttg ttcagcagcc ttcagggtat
     8461 taccgcgtac gtttacgttc taaggggtcg atcatcaatg aattggctaa acgccatcat
     8521 ggaggaggcc atccattagc aagtggtgcg aatgcaaaag atttagcaga agtagaggaa
     8581 atctataaag agatccaaga tatatgccaa tcgtataaga gcagaaaaac agaatgatac
     8641 ttcgttcgaa aacgtgcctt ttgtagtaaa aatcacaaat gtatcttttc aagatcttct
     8701 ttttccgtta caatagtgct cactaaagat tttaaaggag aaagaagatg acattaccaa
     8761 attgcccaga atgtggctca gagtacacat atgaagatcg aggcttgttg atttgcccag
     8821 aatgcgggaa cgaatggaac aaagaagaac aagaaactgt catagaagac ggattagtgg
     8881 tattagatgc aaatggaaac cgtctgttag agggcgatag cgtgacagtg attaaagact
     8941 tgaaagtaaa aggtgcgtca ggtgccatta aacaaggaac aaaagtcaag aacatccgtt
     9001 tagtagaagg cgatcataat atcgattgca aggtagaagg atttggaccg atgaaactga
     9061 aatcggaatt tgtgaaaaag aattaaagaa tattcaaggt cttttcacat tcttttccta
     9121 ctactaatga taaaataaag taaacgaaaa ggagtgaaac gaaaatgtat ggttatggaa
     9181 tgtatggttt tttagatccg acatttcttt tggtcattct tggattagtt atttccggaa
     9241 ttgcgtcagc gtacgtcaat agtactttcc gaaaatacga tcaagtgaga agcaaaaaca
     9301 atgtgactgg tacacaagca gcacaatata tattacaaag tcaacagata aataatgtcg
     9361 gtgttcaaca aattgccgga gatctcacag ataactacaa ttcaggtaat aagatgttga
     9421 gtttgtctca agcaactgca cagtctactt cagttgctgc gataggtgta gcagctcatg
     9481 aatgcggaca tgcggtacaa gatgcttcgg gttatgtccc attgaagatt cgtgcagcac
     9541 ttgttccagc agctaacttt ggttcgatga tttcgttccc cttgattatg gtaggtgtat
     9601 tgcttagctg gaactctacg ttaatcaata tcgggatttt cgctttttct ttagcattac
     9661 ttttccaatt ggtgacatta ccagtcgaat ttaacgcgtc tcggcgagca atccaaattt
     9721 tgagtgaagg cggactactg acggaagaag aagtaccgat ggcaagacac gtattatttg
     9781 cagcagcact gacttatgtt gcagcagcgc tttcgacatt cctgcagctg ttgcgcttga
     9841 tcttattgtt cggcggcaac cgaagagatt aaaataaaga agttgtgaaa tcagcgcttt
     9901 gatctgagct aataccgaga gttagctgat tgaataccat ttatttggaa taagaggatg
     9961 tgacaagaat tttgtcacat cctctttgtt ttgttctcat aacctttttt catatacagt
    10021 tcatgaaccg cttttattaa cttgccaaat aacactgtat tgtgcgttgt atccagatag
    10081 aaagtctccg tttcatctga aattttctca tgctgatctg taatgatcaa atcagcatgt
    10141 tctgaatatg cggtaatttt aacagcatct ttgcgaaata actgctgcaa atggctttga
    10201 agatgataat ttcctgtaaa ctgtttggtt atctgcaaat ggatgagtaa ctgctctttc
    10261 gtttctgttt gtagtaagtg ttggatcaat tgactaaggt attgactgat ttggtttctt
    10321 tccccatttt ttgaaaaaat tgtatcgatt ttttctctta atttcttttc ctgtataaaa
    10381 gaactagaat gattggacgt ggcttctgga aagcaaagtg tagaaaaact actgctggat
    10441 tcacccaaca gttcgaaaaa aacaactgcc aacacaagaa aataaaaata aattggtatt
    10501 ttattttcta aatggttgag aggaaactgt tgagttaagt aagtcatcaa ttgaccgact
    10561 tgtcgacaaa taaggttttt gcttgtggaa
//
LOCUS       DAIGTA010000076        10121 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.079, whole genome shotgun sequence.
ACCESSION   DAIGTA010000076 DAIGTA010000000
VERSION     DAIGTA010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.079"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(559..1599)
                     /locus_tag="NOB43_002394"
     CDS             complement(559..1599)
                     /locus_tag="NOB43_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0983227.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1948..2274)
                     /locus_tag="NOB43_002395"
     CDS             complement(1948..2274)
                     /locus_tag="NOB43_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983228.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2261..3064)
                     /locus_tag="NOB43_002396"
     CDS             complement(2261..3064)
                     /locus_tag="NOB43_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0983229.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3417..3707)
                     /locus_tag="NOB43_002397"
     CDS             complement(3417..3707)
                     /locus_tag="NOB43_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI0983230.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3843..4022)
                     /locus_tag="NOB43_002398"
     CDS             complement(3843..4022)
                     /locus_tag="NOB43_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983231.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4019..4369)
                     /locus_tag="NOB43_002399"
     CDS             complement(4019..4369)
                     /locus_tag="NOB43_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983232.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4362..5687)
                     /locus_tag="NOB43_002400"
     CDS             complement(4362..5687)
                     /locus_tag="NOB43_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI0983233.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6137..6751
                     /locus_tag="NOB43_002401"
     CDS             6137..6751
                     /locus_tag="NOB43_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0983234.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6916..7740)
                     /locus_tag="NOB43_002402"
     CDS             complement(6916..7740)
                     /locus_tag="NOB43_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983235.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(8377..8634)
                     /locus_tag="NOB43_002403"
     CDS             complement(8377..8634)
                     /locus_tag="NOB43_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI0983236.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8627..8896)
                     /locus_tag="NOB43_002404"
     CDS             complement(8627..8896)
                     /locus_tag="NOB43_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0983237.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9027..9206)
                     /locus_tag="NOB43_002405"
     CDS             complement(9027..9206)
                     /locus_tag="NOB43_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983238.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(9587..>10121)
                     /locus_tag="NOB43_002406"
     CDS             complement(9587..>10121)
                     /locus_tag="NOB43_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983239.1"
                     /translation="QTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
BASE COUNT         3098 a         1841 c         1454 g         3728 t
ORIGIN      
        1 cgttgcgggt aataccgtaa cactgaaggg cacgcattaa ggcgtcatct taatgctttc
       61 ctgtaggaca ctgacggaga ttaccagtct cccgagcctt acaggggcct ttcttttttt
      121 tgtattttca attatcacaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac
      181 aagcatatca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat
      241 attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga
      301 attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc
      361 tatttttttg aatgaaaaat aactaaaata tctaacgatt atgactttaa aacctacgtt
      421 tgtgattgtt ttcataaact tttaatctaa aaactccgga ataatagcta tttatttgta
      481 acatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat catttttata
      541 gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg gtaattcgtt
      601 aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga caaaccaatt
      661 ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt tttgtttttg
      721 ataagctttc agcaaagtca tatataatcc tttgtcagca tcaattccat aagattccag
      781 ttcttcataa acaacaactg tttgctctaa ttcttcagct tttttctttg cattatgaat
      841 agtttggacg gttttttgag cgtcttcgta agtactagaa aatgttttta tcaagtttaa
      901 tacattttct ggtacaaatg tatttatact gtcctctttc atgatgtcga cgaagttatc
      961 tagtaaaact tgattttgta actgatcagt ttcagtgtct attatgtgtc tattagtgtc
     1021 tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg agtccttgat
     1081 atgactggat tttgccgtat ttgcgatttt cgcaattacg gtggtatcat tgatttctcg
     1141 cggttttgcc gtatttgcga ttttcgcaat tacggtggta tcagtattgt cttcctcttc
     1201 catgatttta aagacgtctt gattcgttac ttctggcttg cctaagtaca ataaattagg
     1261 catggattca atcttaccgt cacgtttatt tactcttcct ctcttctgtt tcagaagacc
     1321 tgctttttct aattcctttt tgattttaga tactttacct tcgcggcatt gtaacaattt
     1381 cattaattct tcaactgtga atatgaaaaa tatattatca tcagaatcta cccagttatt
     1441 tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg catcatttga
     1501 tagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat atttttcacg
     1561 ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc tttctgtagg
     1621 atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta tccactatat
     1681 atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt ttttatcttt
     1741 ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaagg tttaagctca
     1801 tagtaactat atcacgatat tacaataata ttatatcacg atatcgtaat attacaatat
     1861 gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa tatcacgata
     1921 ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg ctagtttata
     1981 tccttcaatc aagtattctt caggtatgga ctttaatagc gcatcttcta taacgtctgg
     2041 tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca ttagaattgg
     2101 atttatacga atgctatctg ctgttcttac actacttcct tgatctttta tgactttact
     2161 tatatttttc ttggttaatt cgatttcttc tacttctttt gatttaaaat tctttttatt
     2221 tttatttcct agtaatctac ttactgcagc ttgactgcga ttatcttctg ccatcaaaat
     2281 caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca gctgttgagg
     2341 gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg gttattgtcc
     2401 tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg gttgctgcag
     2461 acgtcatttc tttagaaatg ttataacgct tattatactt agtaaataga actcctcgta
     2521 cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt aactttatta
     2581 gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca gaaacagtaa
     2641 atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata taatcatagt
     2701 tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact tgagtaaatt
     2761 ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct ttatagtcca
     2821 gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta ggttggtttg
     2881 ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca atgtccacta
     2941 aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg ctagtcgtag
     3001 ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt aaaatatccc
     3061 ccattcatct tatattataa tataattata tcataatatt gtgatattgc aatatcgtat
     3121 atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat cggttcggat
     3181 ataaagatta ttcatatgtt attcgaaatt aaaataatca ctttttatta ctttaaaatt
     3241 ttttattaat gataagaaat atgttttgcg agcagcaact agaataattt aaacattact
     3301 aaactgtcta tattgttact aataattccc ttcttatagt gcattttctt agaaaaaaac
     3361 aatattacga tatcatgata ttaagatatc gtaatattat acaattgtga ttgatattat
     3421 atatgttttt ttattttttt atcatgttta atcttgaagg aatcatattc tttttctaaa
     3481 gacaggagct tttcataaac atcagacatg tttaaactag aggccaggct taaatcataa
     3541 acgaatgaag caggtaatga ttttattcta cgttgtcggg ttatccagct tgcaaccgtt
     3601 ccttgtgggt aggcatataa ctcacaaaat tgttctacag tgattcctaa attcttgata
     3661 atgtaaacat tgatcgggtg cgagtaaaca aatgtattga tagacatggt gcgtaagcct
     3721 actttctttt attattgcgt ttgcaataat agtttaacac acgcattatt ctagtatcta
     3781 ctcctatttg taaaaacaaa aaaggattca tagagataac tctatagaat ccgtaaaata
     3841 ccttatatat ataacgggaa gatataaaac ctaaaattat gataacctgc tgcagcttct
     3901 acatagaaag agaagcgctc aacaccaacc tcatttatca aacgttggcc ataaccccaa
     3961 atctcttctg atagctgatc aaaggttata tactttagct catattgctg gataatgttc
     4021 attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt tcgtcgtagt
     4081 gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc ttgccaatga
     4141 tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat actgatctat
     4201 tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt tgttcttttg
     4261 ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta tgatcagata
     4321 aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt tttaattccc
     4381 ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct agcgccttct
     4441 aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat cttgtcaata
     4501 attttatcta aattttcttc gtcaatttgc ttttgtggat cactaaataa atccagctga
     4561 agcgaatcgg tgtacacaag cttgctatag gttattccaa cgtgccttac ttcttgtcct
     4621 tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt attatctgtg
     4681 ataggtattt tcatctggtg tgaaaatcct ggtctcgttt ctaagatcga cgtaccaatg
     4741 tttaaatgaa cacatcctgt tttacaatta tgctgcctga tacgaatggc tacttgttcc
     4801 gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg tggtaacact
     4861 tgtgaattac cataagattt ttcctttgtc ggttctggcg ggattgctat atctgttcga
     4921 tcgattccgt tagcatggaa gtacagctgt aatccaatca cacctaatct attcttaatc
     4981 gtataaggat tccagttagc aaggtctcta atgctcaaaa ttcccatttg gttgagcctt
     5041 tttttcattc gcgaaccaat tccccaaaag tccgtcattt cgggaatatt ccatactttc
     5101 tcaggaacgt tttcgtacgt ccattccgca ataaatcctt cattatgctt tgcttcattg
     5161 tctaaggcta atttagccaa aaggggatta tcgccgacgc ctaccgtagc aatcaaacct
     5221 aactcttctt taatacgttc ttggatcatt tgagcgagct tcttccttcg ctgacttcgt
     5281 gtttcttcag tcgtaaaaag attcagtgat tttgtcactt ttaaaatcga ttcatcgatc
     5341 gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt tacctgcata
     5401 tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt aggaaatggt
     5461 tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt tgcttcagga
     5521 gaagaagcta atatcaatcc tgaaccagta ttatcagatc gactcataac aacaagttct
     5581 gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa gcttttcata
     5641 tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa taacactcca
     5701 ttcttccaca ttatacaaac atatgttcga tgttgtaaag aagaaatagc taaatacata
     5761 aaaaaagaag cataggtatg ctatcaccct gcttcttctt ttgatttgta tgatcaattt
     5821 gttctatcac tttactaatt aatttgaaaa tctaataaaa actctcactc taaaagagtg
     5881 agagactgca aattagagta cggacttttt tggagttccg ttctttaata ttaacaaatg
     5941 aataaaatcc ttacaacatt tgagaataag ttatcagtag acacttacaa aaaattctca
     6001 tactatttcc tccatcatta gtttttgtct atataaggtt taccctaaat agacactggt
     6061 ataacattga aaaatatggc ttcctcgtgt atgattaggg tgtattttaa atagttgcag
     6121 aaagtaggta aaagttttga gagttgcata catacgtgtc tcatcgatcg atcaaaatga
     6181 acaacgccag attgaagaaa tgaaaaaatt cggtgcagag agaattttca tcgagaaaca
     6241 atctggcgca acgattactc atcgacctgt tttccaagaa gcattagatt acgtccgaga
     6301 tcaagatatt tttattgtgg aagctattga tcgacttgga agaaattatg acgagatcat
     6361 cgcttcagtc aattacttga agaagaaaaa tgtgaagctg atcattacta gtttaccgat
     6421 catggctgaa gcaattggca atcctctcct ggataaattc attaaggatc tgatcatcca
     6481 aattttggcc atgatcgctg aacaagaacg gactgaatcg aaacgtcgcc aggcacaagg
     6541 aattaagatc gcaaaagcaa acggcgtcta caaagggcgg cccaaattat acagtgcaga
     6601 cgcaaaagat ccccaacgtc gccttgttta caaaagcatc gttgaagatc ttaaaaatgg
     6661 tgttgcgatt gctaagattg ctaaagacta caatgttacg agacaaaccg tgtatagaat
     6721 aaaaaaagac agcatggtca atgacaaata gttgatcatg ctgcttttat tatcttctca
     6781 tctttaattt cctacatata attactatct ataaaattaa gtcttactca gaacagataa
     6841 agcataaaat tccaacaaac cattttttac ttaactaaat aaagagtctg ttaatataat
     6901 cttcacttat ttacgttaat cccctactgt atttgttggt tccttatcta tattttctac
     6961 aaaatcctta ttatcttgtg atttagcttc gtataattct ttgtatgtcg acacattggt
     7021 tatactaatt cctatagcta gttcttgaga ctctactttt ctctctagct cctttgacaa
     7081 agtgatttga gatttatttg gttccgttgg agtcaattct atagattctt cataaaaatc
     7141 tctatacata aagctatcat taattttata aaaaaaatta aatgttttta gcactgccat
     7201 ataacattca aaacattctt ctatagttgg tttacttcct tgaggagaat gaaccaattt
     7261 attacgtttt tctatgaaat ttttaatttc ctttcttatt tctttcggaa actcaatatt
     7321 aaagtaccct ttaaacatgc tccctaataa tttgtctaca gggggagatt gtaaattctc
     7381 aaatattaga gttaaatcag gtttctcttg ttgataaaat tcctttaccc ctatttcaca
     7441 ggctgtaatt atcgaaataa acctatctct agtatttgat atatttttac ttcttttaag
     7501 gagtataaga gaaaagggga tactttcgtg tccatgcatg taattaacta attgttgagc
     7561 ttcagaagtt atatctctaa ttatatagtt aacggaatta ggaagtgtct ttaactctaa
     7621 tgaaatttct atccaattac tatcttctaa tctgtatatg ctcgaagtat aatttgattc
     7681 gtcagcaagc atcgctacat cccaaacact gatcataaaa tcttttaaac gttcaatcat
     7741 ttcagcaata ttgctaaaat cagctaattt ttctttagaa taaaaaaaac atttatatca
     7801 gaatcaataa attctatttt tttattacta tatcgtcatc attatcttga ccatttatgt
     7861 ttattgttcc ctgagtgggg agtacttctt tcaaattcaa gttaaattta tattccatta
     7921 cttctcctcc aatatataaa aattacttaa ctgtatccaa atttaatatg taaataaatc
     7981 attaattttt agctaaattc tatgagaagt ttatttttgt tgtttttgct aattaactaa
     8041 aactagtaca aaaaatttaa aatagattat taaacctatt gcttattcta ttcagtcata
     8101 tatataagcg tcatccttta gtaactaaca tcccacacta caatagtatt ataacatatc
     8161 tattcaactt caaattgttg aaatttaagc catttatatt tacttttcct caactttaga
     8221 aatgatttta ctaaccttat atccgtaata cgcgtaacaa acacattcat taataacaat
     8281 caacactaag ctatattagc tttttaaatg actagggtaa ataaaataag gatcaaaaac
     8341 ttttaagttt ctgacccttt ccttacttcc gattggttaa tagtgatctt ttgcagaata
     8401 aataaatatc gtttcatttt caactctata tatcagtcta tgttcatctg taattcttct
     8461 ggaccatttt ccagataaat catgctttaa tggctcaggt tttcctaatc cagcaaaggg
     8521 ggaacgatcg atatctttta ttaacttgtt aatctttttt atattgcttt tgtttccttg
     8581 ctcatgccaa taaagataat catcccaagc atcatcagac caagccttaa tcatcagatt
     8641 caacctcgat taagtcatgt gttttaaatg cacctttgga gaattgttca tctcctcgac
     8701 gaattttttc catgacgtaa ttattagaaa gtgttctcaa cgtttcttgc atagaatcat
     8761 aatctctttt tgataataca acaactgtat cttctacatc tttacttgtt acaataagtg
     8821 tttcagcatc ctcattaact tgtttcatat aactacgtaa attttggcgg aaatttgaat
     8881 aagctactgc ttccattcct ttcacccctt atttatttct ataaaacaat tgtacattat
     8941 attgtacaat taagcaaatg attaatattc taacttctta taattaaaag tgctatcact
     9001 tttagttttt aggataaaaa gtgacgtcac tttttgagtg ctggtacctc aaatcctgct
     9061 ttttcttggg caatcaataa atctaacgca atacacataa tcctggattc acttttgccg
     9121 tacttctgct ttagttgctg caattctttt tgtctctttt catccaacgt aacgggtaac
     9181 cgtttatttc ctattgcaat tggcattagt actctctcct ttcatcgaaa taaccctatg
     9241 aaaaatatgg ctgcaatcat cttgaatagt agactcacaa gggctaatac aaagcgccaa
     9301 aagatcaaac aaaataccag tattgccaaa aatactacga agtttaaatg cacagctgca
     9361 gcatggcgca taagtatttc gccaacaaat aggactaaca atagaggaat gattttattc
     9421 atatggatct ccttctttct cttaggttat cgggtgttgc ccgcttattt cgcaccacct
     9481 aagcggcggg ggcggttgga gcgattggtg cgaaataaga accattccct tagttactag
     9541 gttttttgtc cttatttcac acattctcac ttttcggtat aaatgattat tgcctttttt
     9601 tcctttcaaa tcgttgatat ggcattcgtt tacggtcaag ttcattttgg atttcttctg
     9661 tatcgtcgta agtataggtg tctaaaaaat cagttaaagt cgtgtaccag tcgtcgcctg
     9721 ggttatctac ttcttctaca tattccctca aaaatgcttc gggtacagcg agttcataat
     9781 ccattcccat taacacgata gattccgttc cacacgtcaa aaatctagta aatacaaggt
     9841 aataatcgtc tatcgtcgca tctttgctgt ttagctcttc catttcttct tccattaatt
     9901 ccatgctctc aaaaattgaa taatattctg attctgagta atagtgtttc ctgcaaatcg
     9961 tgtagctgac aaagttttcg accagctcac tcctttctag gtaaacattc atgatgtatt
    10021 tttctgtttc tagtcgtaga agctccgttc ctttttttac cgtttcagga cgacgtttat
    10081 acacgtctaa acgattatgg ctgactgtga ccttcgtttg a
//
LOCUS       DAIGTA010000077        10050 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.080, whole genome shotgun sequence.
ACCESSION   DAIGTA010000077 DAIGTA010000000
VERSION     DAIGTA010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.080"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..968)
                     /locus_tag="NOB43_002407"
     CDS             complement(<1..968)
                     /locus_tag="NOB43_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0983240.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLK"
     gene            complement(959..1627)
                     /locus_tag="NOB43_002408"
     CDS             complement(959..1627)
                     /locus_tag="NOB43_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0983241.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(2083..3069)
                     /gene="lacD"
                     /locus_tag="NOB43_002409"
     CDS             complement(2083..3069)
                     /gene="lacD"
                     /locus_tag="NOB43_002409"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI0983242.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(3082..4008)
                     /gene="lacC"
                     /locus_tag="NOB43_002410"
     CDS             complement(3082..4008)
                     /gene="lacC"
                     /locus_tag="NOB43_002410"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HCI0983243.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(4021..4536)
                     /gene="lacB"
                     /locus_tag="NOB43_002411"
     CDS             complement(4021..4536)
                     /gene="lacB"
                     /locus_tag="NOB43_002411"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HCI0983244.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(4555..4983)
                     /gene="lacA"
                     /locus_tag="NOB43_002412"
     CDS             complement(4555..4983)
                     /gene="lacA"
                     /locus_tag="NOB43_002412"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HCI0983245.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTREHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(5003..5776)
                     /locus_tag="NOB43_002413"
     CDS             complement(5003..5776)
                     /locus_tag="NOB43_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0983246.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            5941..6420
                     /locus_tag="NOB43_002414"
     CDS             5941..6420
                     /locus_tag="NOB43_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0983247.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            6477..6779
                     /locus_tag="NOB43_002415"
     CDS             6477..6779
                     /locus_tag="NOB43_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HCI0983248.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            6801..8258
                     /locus_tag="NOB43_002416"
     CDS             6801..8258
                     /locus_tag="NOB43_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI0983249.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(8851..9603)
                     /locus_tag="NOB43_002417"
     CDS             complement(8851..9603)
                     /locus_tag="NOB43_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0983250.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(9818..>10050)
                     /locus_tag="NOB43_002418"
     CDS             complement(9818..>10050)
                     /locus_tag="NOB43_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HCI0983251.1"
                     /translation="KMYQVFEEMGYPIKTVTRKLEVIKADDTISDLLDVEEGDPMFYF
                     HTQGFSLERLPVEYSISKYRGDINYFVFELAQ"
BASE COUNT         2855 a         2214 c         1714 g         3267 t
ORIGIN      
        1 tgcttgagcc catgcactcg gtactgatga gaaaaaattg atgcctgttt ctcctgagga
       61 atgccaattc cctgatcttt tacttcaata atcacgctac ccttttggtt tgaaatggtg
      121 acaattacca gttttccttc accatatttg attgcattgt caactaaatt cgaaaccgcc
      181 cgataaatcc aacgatctcg tccatgaatc agggttggtt gatcttcagt aaacgcaaac
      241 aaaagattcg gataattcat tttgtaggca tcacaaactt ccgcacagat cagtgaaacg
      301 tctacgactt ccgtgctaag atcctctgag ttattggata atgtcaaaat atcgtcaata
      361 ctgtcggtca tccgatctaa aagcattaaa tttccttgat cggcatgttg ccgttctatt
      421 tccagattcg tacgcaaaat agcgatggca tttttctgct cgtgggtcag ataactattt
      481 aatcgtcgat aatcctccaa atgaccatcg aacttatcct ttagcttatt aaaagccgca
      541 tttaatgcct cgtccttcac agtattttta ggaacttgat caataaacgt taaatcacgc
      601 gtaatcgcta agatttgatt actgtaaatt ttgcgtaaaa ccaaccaaag aataaacgtt
      661 aataacatga cggcagaaca aataaccagc accatcgctg gtaaatattt aaatagttcg
      721 tcctggtaag ctttatctat catcgaaata gtcataaatt gattgttgga agatttcgaa
      781 gcttccatct gcgtctctgc ttgaaccgtc ttaccctctt ccataaaata aacatcttca
      841 cctaaggtag atgcgatact gattccctcc aaattatttc tcagaaagaa gaaactcact
      901 aaaatcacgc ctgtcaccaa cagtgaaaaa gccagcatcg ttaacgtcat tttaaaattt
      961 aatagcatag ctggtacccc tttgctcgaa tggtttttaa gacctctttt tcagctgctt
     1021 cagccagttt cttttttaga cgagccagat gcactcgcag aaccgacgaa aaaggatcaa
     1081 aatcttcatc gtagacatgt tcagaaattt cctcagacga aacaaccgct ggatgacgct
     1141 gagcgatgca cagtaagata tcaaattcct tgggtttcag gaccacctct gtcttttgat
     1201 agctgaccct tcgacctaat ggatcaatct tcaaagcacc aattgaaatc tgcggcagcg
     1261 cacgtccatg ataacgacga ataaccgcgc gtattcgtgc ttttaattct agtaactcaa
     1321 agggtttgac taaataatca tctgctccaa aatccaagcc ttttgctcgt tcttcaatct
     1381 catcacgtgc agtaataatg ataactggac tttcgacttc ttcagcacgg agactttgta
     1441 aaacagataa tccatctttt ttaggcagat ttaaatctag tagtatccca tcgtatgaat
     1501 tgatgaaggc cttctcttct cctgactcgc catcataagc tacatctaca gaaatattct
     1561 cctgctctag gccctttttt acggataaaa ccagctcacg attgtcctca accaccagta
     1621 cacgcatgta tattcactcc tcatacggat ttagtaatta cacttatgct ttttagcata
     1681 gtacacgctc ttcttcaaag tccacgttct ttttgtgaag atttgaagaa attcatacat
     1741 tctgttaaaa aacacataat taagaatgat tttactgttt gaaaatacct agaatagaaa
     1801 aagactggaa cctttcctcc agtctcacta ctttctattt gcttggtttt cttgtatata
     1861 cttttcaaag ttcgttggtt tatgaccaat aagcctcgtt agaatactga aaattgccat
     1921 caagtcatta agtaccacat gtaagaaaat ctctctaaag aaaaacccct tcgttttaac
     1981 tcacttacta ttttagaatt cgttccccta ataatgcagc atgattttac gctttatgta
     2041 taaaaaaaga ctgcaagcaa ttgtgcttca cagtctgatt tcttatgata gtgagcttgt
     2101 taacacttcc accggtgtag cagtttcttt caatacggca tttaattctt caatattttt
     2161 acgcccttgc gtattcatcc actccatcgc tgcttctttt ccatcaacga tatagctttc
     2221 tacaccatct gcccaagtcg cacggccgca aagtacacca ttgaaggttg agccggcatt
     2281 tttcgcgaag cgcagtgttt cttggaacaa ctctgctttt acaccggcgc ttaggaaaat
     2341 aaatggcagg ttagtggctt cagcctgttc cttgaagaag ttagccgctt gtgcctttgt
     2401 gtacacgact tcgtctgtcc catagccttc cacataattc atattgacgg gtacttccac
     2461 ctttaacaca tctacgccat aacgtggatc agaaaattcc ttcatcatat cgttgacttt
     2521 atgaggtttc ttaatggcgt attctttcga agtcgcatca gagatgttcg cgtcataaga
     2581 aacaagctcc aagaagaagg gtaagttttc agcctgacat tctgagccga ttcgttcaat
     2641 aaaggcatgt ttttgattat tgatttcttc tgcttcatcg acatcatagt aaagtaggaa
     2701 cttacaagca tcggcgcctg cttcttttaa acgtttaact gaccagatcg ataataaatc
     2761 tggtaaacgg ccgggagttg acgcatcgta accagttttt tcataagcta acagcaagcc
     2821 ggcatttttt gctctaacgt cagctgctgg caagccatat tcgggatcta ataaaatcga
     2881 tgaggcatat ttcgttaatt gtgaagaaac aatttcttta aattcaacga tttctgattc
     2941 ttctgcttcg ctgcccttga attttgtgat catcttcttc aaagccccgc gttgatcaat
     3001 tgctaaggcc ccaatcactc catcttcatt gcatagttgc ttgatatatt gacgtttttc
     3061 ttcgttcatt tccgtatcct cctacacttt ctccactaag atttgatcat atagtttttg
     3121 ataattggct aattggacat agccagtcgt cgcttcctga gcattcagca ttcctaaaac
     3181 attaccctgt tttaacacgg cttcatccga aagaccttgt tgaatcgcag cggtcaatcc
     3241 ggcaacggtc gcatcaccag agccaactgg attgacgaca tcaatctttg gaattgtcac
     3301 gcaataaaaa gtctcgtgat gtttggcaaa ggctccgtcg ccccccattg aaaccactat
     3361 ccattcaatt tcatcaaaca tcgaatctga caaggcggct tttaaatctg ataattctgt
     3421 tgagatttct cgtcctagca gaccagccag ctcttcggta ttgggtttta ttagcttagg
     3481 ctttacactg cctcgcaaca cttcccttaa tgctgtacct gaacaatcta aaacgacagg
     3541 ctttggctga caaacttgca gcatttgtcg ataaaaatca gcaggcaatc cttctggcaa
     3601 gcttcctgaa aaagaaatga tttcggcttt aacagctaat ttttcgaaat gttgcaagaa
     3661 cgcccttgct tcttgttcag taataacagg tccgttttct aggatttccg tctgttttcc
     3721 gtcatgtaaa acagcgatgc aattacgtgt ctctccgctg ataggtaaaa agtcatgagc
     3781 aatctcattt tgagtcaggt cctttttaat ctcttcacct aaaaaaccgc cgattaaacc
     3841 actagcaatc acctccgtat ctaattgctt caagatacgt gtcacattta ggcccttacc
     3901 gccagctgtt ttgcgaacat ttcttactcg attgactgtg tcgagcttga aggtttctaa
     3961 tggataagaa atatcaatcg atggattcat cgttattgtt aaaatcattt gtccacccgc
     4021 ttaatcgtgg tattcgccac gatcccattt ctcgataaat tcatcgaaga aatgcggatc
     4081 agactgcttg tcactggctt tttcgacgtg atcgattttg gcgatcaatt ttttgttttc
     4141 ttcagtttct tgataatcgg cattgatgaa ggcctctaat atgtcacaga tcaaaaattc
     4201 tcccgtaatc cgagcgccaa agccgatcac attggcattt agttgttcct tcgcatagat
     4261 agcagtcgtc atatcgcgaa ccagcgcact gcggatacca ggtactttat tgacagcgtt
     4321 gttaatccca acacctgttc cacacaaaca aactcctaga tctgcttctc cgctagtcac
     4381 ggcctctccg actttttttc cgtagatcgg ataatgggtt ctggtaaagt cataggtccc
     4441 catatccaac acttcatgtc cttttgattt taagaaatct gatactgcca tttttgtatc
     4501 tgtgacgatg tggtcacagc caattgcgat tttcatttca ttcatccttc ctaattacgc
     4561 cattttattt aacatgtcga cacgtacttg atgacgaccg ccatcataat ttgcttgtag
     4621 aaattcctta acaatattca acgccaactc atcgccaaca atttttgatc caagtgtgat
     4681 catccgagaa ttattatgtt cacgggtcat atacgcactg cgctcatccg aaacttctgc
     4741 tgctaccatt cctttaacct ttgttgccgt gataaagctg ccagcgccgt agccatcaac
     4801 cgcgattcct aaactacctt cgttttcatt cagatcattt gcgatcgcca aagttgattc
     4861 cacaaaatct tctgaagccg tttcactctt atctactact gtaatacctt ctttgatcaa
     4921 ttttttcttg attaattcct ttaattccat gccgtcactg tctgaaccaa ttactacacg
     4981 catttttgtt tcctcctatt ttttactgaa tgattttagt gaattgctga taataactct
     5041 tcagctcggc tgaaagagta gaatccgtaa ataatttgtc gatcttgcgc aaatcataga
     5101 aattataaaa atcgctatgg tcgaatttgt ttgcatctga aaccaaacat ttttctgccg
     5161 cattatctaa aacaattttt tgcaaggtac cttcttcaat actgaaattc gaaacctccg
     5221 aacccttcaa tccattcact ccgacaaaag ccttcttaat accgattttt tgaacagctt
     5281 cattggcaat tgaaccgaca aaggctccag tcttttcccg atatagccca ccgatcaaat
     5341 acagttcaaa tctttttatt tcacttaata gattgaaaac cggcagacta ttggtaacga
     5401 ttcggagaga tgacggcttg atgtatcgtg tcattaattc gatcgttgta cccgatccaa
     5461 gaaaaatcgt gtcgtcttct tgattgatat gagctgccgc atttttagcg atgtattcct
     5521 tctcttttgt atgcagcttc tttttttcag tatgagaaag ctcatttgct tctatagaag
     5581 tcgacatttc cagataatcg attttttgtg caccgccatg aacgcgtaaa agctttttct
     5641 tctgcgcgag ttcctctaga tctcggcgga tcgtcatatc tgaaacattc agtacttcct
     5701 gaataaattt gactgttatc gtcccatagc gatcacacat cgctaagatc gaacgctgtc
     5761 gttctgtttt cagcatattc tgtacctcca cgaccttata ataaaacatt tacgaacatt
     5821 tttcaacaca tattgttcgt ttattttcgt ttatgcgttg acaatgattt tgtaagcggt
     5881 tatactcaac ttgtaaacag ataaataaac ataaacgaac taataaagga gctgttttgt
     5941 gtgaatgaat tctttttcaa agacactgtc tatgtttctg acaagcagtc gcaggaagaa
     6001 gtgttcgagg aagtctatca agatctgtta aagaaagaat tggtaaccga agattttttg
     6061 gagaaccttt tagaacggga gcgtaattat ccgacgggat tagatctctc acctgtctct
     6121 aaaatattgc cagatatcgc tatccctcat accgaaagtg agtttgtgcg aaccacccgt
     6181 atcattccaa tcaaagtaaa aaatgaaatc cctttctaca acatgatctc gccaagcgat
     6241 cagatttccg cttcatttct tttcatgatc ttgaacgaaa atggtgaagc acaggctggc
     6301 atgttggcta atatcatgga tttcattaat tctgttgacg aagaaaaact gttttcgttt
     6361 ttcaaattag aggacacaga agcgatttat cattttttag aagaacattt ttatatatag
     6421 aagtctctgc ctaaccgcag gataaaaaat aaacttattt taaggggaga attattatga
     6481 tcaaaatttt agcagcatgt ggagcaggcg ttaattcaag ccatcaaatc aaaagcgctt
     6541 tggaaactga attgaaaaat cgtggctatc aagtcacctg tgacgccgtt atgatcaaag
     6601 atatcaatga agaaatgctg tctcattatg acattttcgc acaaattgcc aacaccgact
     6661 tgggttttga cattaacatc cctgtcgttg atgcaggtgc tattctttat cgtattcctg
     6721 ctatggctga gcctgtttac caaagtatgg aaagcgcaat ccaatcatta aacaaatagg
     6781 actaaagaaa ggaaaagcat atgaatacaa ttattgatat tgccaataaa gtatttaccc
     6841 ccctaattaa tttaggtgcg gcaccgttaa tgaccatcgt attaactgtt attgctttat
     6901 tttttaaagt aaaaccgtca cgcgctcttg aaggcgggct caaattaggg atcgccctga
     6961 ctgggatcgg agctattatt ggaattttaa ctactgcttt ttcagacgct atgacagctt
     7021 ttgttgaacg cacaggtatt tcattaaaca ttacagatgt cggttgggcc ccactagcaa
     7081 ccatcacatg ggggtcgcca tacacgcttt attttttact aattatggtg atcgtcaata
     7141 ttgtcatgtt agcaatgaaa aaaaccaaca cattagatgt ggatattttc gatatttggc
     7201 atttagcaat tgttggtttg ttcgcgatct tctgcggtgc taatctgttt attgcttctg
     7261 cattagttat tttcattggt gtattaaaaa tttggaactc cgacttaatg aaaccaacct
     7321 tcaatgactt gttaaatgcg ccagacagca acccgatgac cacgactcat atgaactaca
     7381 tgatgaatcc gattattatg gttttcgata aaattttcga caaaatcttc ccttggttgg
     7441 ataaatatga tttcgatgct gccaaattga atagtaaaat tggcttctgg ggatcaaaat
     7501 tcgcgattgg aatttatttg gggatttttg ttggattact agcaggacaa acaccaacgc
     7561 aaattttctc gctagccttt accgctgccg tctgtttgga attgttctct ttgataggcg
     7621 cttggttcat cgcagccgta gaaccgttat cacaagggat taccgatttt gccaataaac
     7681 gactaaaagg acgtaccatc aacataggtt tagactggcc tttcatagca ggccgcgctg
     7741 aaatctgggc tgccgctaac gtattagcac caatcatgtt gctagaagcc atcatcttac
     7801 caggaaataa attattgcca ctaggcggaa tcatcgcaat gggtgttacc ccagcactat
     7861 tggtcgtaac tcgtggaaaa ttaatccgta tgatcgtaat cggcgcgatc gaattaccat
     7921 tattcttatg gtccggcacc ttgatcgccc cgttcgttac tcaaacagct aaagcagtcg
     7981 gagcctttcc agccggcttg aacgggtccg ccatgatctc tcatacaacg atggaaggcc
     8041 cgattgaaaa attcctaggt tatttagtcg gtaatgcttc tcaaggacaa atcgaatttg
     8101 tgatatacgc tgccttagca ttaggtgcat accttttaat cttcatttgg tacgctcgtc
     8161 aaatgaaaaa acgcaacgct gcatacgcag ctgaaaaaga agagaatgca tctccggcaa
     8221 cggcgcataa tatgacttat gcagccgaag ctaaataagc taaaaacacc ccgaatgtct
     8281 ttagacttcg gggtattatt ttacctataa aaaataaata gatgtaaaat ccatttcaaa
     8341 aagcatagcc catctcttgc cacacccaat aaagaaatta tcaacgttta tgcttttttt
     8401 aactccttta agcttgcctt tgttggtatt cctcaacgat tctttttgtg ttcttgtttg
     8461 ttttgtgctt tttgactttt tgttgtttaa ttgcgaattc cttgatttct tttttcctga
     8521 atcgcttcgc atcccgcggt tatgcgtgcg atttcatcat tgctttttct gatctaactc
     8581 gtttcatgtc aaagagcttc agctgactta gtgtccatgg ttgttttgat atcccttttc
     8641 ctccttaata aagcggtgat tgatactgct attttttcct tcacataaac ataacatccc
     8701 aaaaaaatcg actatctttt ttcaaatggt gtattcaagt attcggagga attagtaatg
     8761 atgcacccta aaaataacat aattcgctta aattcaaggc taccaaaaaa ctaccaagtt
     8821 ctaattatct agagtttggc agtttctcat ttacacaaca tatttttctt ctttttcgat
     8881 tttttcatag tgcttttgtt catcatcatc cgttataact actgttacat cattcagatt
     8941 ataatatact gaaaaatctc ttttcccaat tttcgaatga tcaatcaata aaaagcgttc
     9001 aacagaatta ttcagagcga tctgttgagt ttggccctct tcaaaagtcg aagtcataat
     9061 tttctgttca tttaaagcat tacagctgaa aaatgcttta tgaaaattca tatcctgtag
     9121 cgatttattc gtgatttcac caacaaagca ttgagtcgtt tcccgcatct cgccacctaa
     9181 tagatagatt tttcgattcc cttttcgctt atttaattct tcaaaaacag gcaaacagtt
     9241 tgtaacaatc cgcagtgaat ccccttgaat gatttttgac atgagctcga ttgtagttcc
     9301 tggtccaaga aatatcgtat caccatcatt gatcatttca ttcgcctttt ccacaatccg
     9361 ctgcttttct tcttgcagca taatctgttt ttctctatga gaaagctcca catgccgata
     9421 aaaatccttc aatttcgctc cgccatggac gcgttctaat aatccttgtt tctccatttc
     9481 gtccaaatca cgtcggactg tcatatccga aaccgaaaac ttctccataa tatcgctgac
     9541 tcgtactgta ccgttaacct ctaataacga catgatcgct tggaatcgat ccgtttttaa
     9601 catttcatcg cctcttttct ttttaagact atcaaattct taagaaaagt gctagaacaa
     9661 gttttcttaa gaagccttct gcaggaagga aagcaaaatt tttcagaatt tgcaagctgc
     9721 tattctaaaa aataaaaccg aacgagcatg actgtcatag tgacagcctt gttcattcga
     9781 cttttatctt taataaatca ttttatttaa tctgaagtta ttgtgcaagt tcaaaaacaa
     9841 agtagttaat gtctcctcga tatttcgaaa tcgaatactc aacgggcaga cgttctagcg
     9901 aaaaaccctg cgtatggaaa tagaacattg gatctccttc ttccacatct aacaaatcgc
     9961 tgatcgtatc atccgctttg attacttcta gttttctggt gaccgtttta attggataac
    10021 ccatttcttc aaaaacttga tacatttttt
//
LOCUS       DAIGTA010000078         9983 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.081, whole genome shotgun sequence.
ACCESSION   DAIGTA010000078 DAIGTA010000000
VERSION     DAIGTA010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.081"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..826
                     /locus_tag="NOB43_002419"
     CDS             <1..826
                     /locus_tag="NOB43_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0983252.1"
                     /translation="KQLRTIGKTSVIPCIFAVNEPLLFGAPMILNPYMLIPFVVAPIV
                     NAWICKFFVDNLMMNGFIYVLPWATPAPIGIFLDTNFQLISIVLIVLLLTLDAFIYMP
                     FLKAYDKVLLKQEAARTEGEAISGGIVAEKPIEEMKSADPDPEISLQINKLSDRENSL
                     KVLVLCAGGGTSEQLANALKIGAEETKFNLVSKAAAYGNHYSLLPNYDVVVLAPQIKS
                     FYKDIKQDTDKHGILLIPTKGFEYIELTREPAGAIKFITEKLTDSKLKDELASYLS"
     gene            887..2035
                     /gene="dgoD"
                     /locus_tag="NOB43_002420"
                     /pseudo
     CDS             887..2035
                     /gene="dgoD"
                     /locus_tag="NOB43_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
     gene            2044..3039
                     /locus_tag="NOB43_002421"
     CDS             2044..3039
                     /locus_tag="NOB43_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HCI0983253.1"
                     /translation="MIKDIITIDVGTTNTRVSLWRDEELQEVFVYSQGVQKASLAGNN
                     DTVKKILECSIKKLFKKYNILAEKTVIIASGMITSAFGLVEIPHLNAPVGIQELAISM
                     KQFSFPEVCPQPIWFIPGVKTQCQDKSRLSSIQYDVMRGEETEAMAVFSLLKPTISDE
                     HIFVMPGTHTKFIKLDKNGRIVKSKTATTGEILSLLTKKSLIATDVHHRFYDELDESY
                     LLSGFHSARSNGIGSAVFDVRILGQTHNASRNQRANYLLGAVLSSDIQLLENFLEPNE
                     TVVLTGKKELREAIHVILNDLDNFSHPIIIIEANDLAGRGALLAGKKRGLLRKEG"
     gene            3044..3670
                     /locus_tag="NOB43_002422"
     CDS             3044..3670
                     /locus_tag="NOB43_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HCI0983254.1"
                     /translation="MELENYPKATAILRGYTYEEAMLVIRVLSEFKHFIGVEVTTNNS
                     DHLKIIHDGKNRFGDKISIGVGTVVTVEQAEEAIEAGAEFMLGPQKFNDKIFKLAKRK
                     GVLTIPGAMSPTEIFKMFEMGADIVKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQ
                     TNAQNYLNNGASYVGIGSKFFEKSAVHQLNYERLMELAESFIDSLRVE"
     gene            complement(4064..5071)
                     /locus_tag="NOB43_002423"
     CDS             complement(4064..5071)
                     /locus_tag="NOB43_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0983255.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLIVRKSFIPKEE
                     V"
     gene            5538..6944
                     /gene="lacG"
                     /locus_tag="NOB43_002424"
     CDS             5538..6944
                     /gene="lacG"
                     /locus_tag="NOB43_002424"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI0983256.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            6967..7290
                     /locus_tag="NOB43_002425"
     CDS             6967..7290
                     /locus_tag="NOB43_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0983257.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVRKGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            7301..8983
                     /locus_tag="NOB43_002426"
     CDS             7301..8983
                     /locus_tag="NOB43_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HCI0983258.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVAATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFG
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
     gene            9190..>9983
                     /locus_tag="NOB43_002427"
     CDS             9190..>9983
                     /locus_tag="NOB43_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0983259.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEGDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRR"
BASE COUNT         3210 a         1554 c         2113 g         3106 t
ORIGIN      
        1 aaaacagctg agaacgattg gtaaaacttc ggttattcct tgtatttttg cagtgaatga
       61 accactatta tttggagcac caatgatttt aaatccatat atgctaatac catttgtggt
      121 ggcgccaatc gtaaatgcat ggatctgtaa attttttgtg gacaatttga tgatgaatgg
      181 atttatctac gtacttcctt gggcaacacc tgcgccaatc ggaattttct tagatactaa
      241 tttccagctg atatcaatcg tattgatcgt gttgttgcta acattggatg ctttcatcta
      301 tatgccattt ttgaaagctt atgacaaagt attgctaaaa caagaagcag cacgtactga
      361 aggtgaggct atttctggtg ggatagtagc agagaaacct attgaggaaa tgaaatcagc
      421 tgatcctgac ccagagatta gcttacaaat aaacaaactt tcagataggg aaaattcttt
      481 aaaagtatta gttttatgtg caggaggagg gaccagtgaa caactagcta atgcgttgaa
      541 aattggagcg gaggaaacga aattcaattt agtttcaaaa gctgcagctt atgggaatca
      601 ctattcatta ttgccgaatt acgatgtggt tgttttagcc cctcaaatta agtctttcta
      661 caaagatata aaacaagaca cagataaaca tggcatttta ttgattccga caaaaggttt
      721 tgaatatatt gaattgacga gggaacctgc aggggctatt aaattcatta cggaaaaatt
      781 aacagattca aaattgaagg acgagctagc gtcgtatctt tcataatgga atcattatcg
      841 atcaattgtc agattacgaa aatttcaaaa gatagaagga gttcaaatga agattacggg
      901 atataaaacg tatatggtgc ctcctagatg gctattctta aaaatcgaaa cggatgaagg
      961 tattgccggt tggggcgaac ccgttattga aggaaaagcg gcaagtgtcg aaacagcagt
     1021 tcatgagttt atggatcagt tgctaggtga tgatccatct gctattgaag gctgatggtc
     1081 aaaaatgtac cgcagcagtt tttaccgagg tggtcccata ttgatgagtg ctattgcggg
     1141 tattgaccaa gcgctttggg atatcaaagg gaaaacaatg ggacagccgg tctttcaatt
     1201 actgggtggt gcagtccgaa ataaaatcaa agtgtattct tgggtaggag gtgatcgtcc
     1261 tcacgatgta ggggcagcgg cactagaaag aaaaaattca ggattcaaag caattaaaat
     1321 gaatgcaaca gaagaaatgc agattataga cagctatgaa aaaatcgatg aagtagtgca
     1381 tcgcattgag gcggtccggg atgcttgtgg tccgtatttc ggtatagcag ttgactttca
     1441 tggtcgaatc cacaaaccga tggcaaaagt gttagcgaaa gctatagcac gctttaatct
     1501 gttgttcatt gaagaaccgg tattgtcaga aaacaataaa gcactaagtg cgattacaca
     1561 actggtggag accccaattg cgactggcga acggatgttt agccgctggg attttaaaaa
     1621 tattttagag agcaacaatg ttgatattat tcaaccggat ttatcacatg ctggagggat
     1681 tactgagtgt aaaaagatcg caaacatggc agaagcgtat gatgttgctg tagccttcca
     1741 ttgtccgcta ggcccgatcg ctttagctgc gtgtctgcag ctagatgctg ttgttcaaaa
     1801 tgcatttatt caagaacaaa gtcttggaat ccattacaat gatggcaatg atctgatgga
     1861 ctacattaag aatccagaaa ttttcgagta tgaagacggt tatgtaaaaa tcccacagtt
     1921 accaggattg ggtgttatcg tggatgagga gttggtgatt gaaaaatcaa aaatccctaa
     1981 taattggcat aaccccgttt ggcgacatga agacggaagt atcgcggagt ggtagatgaa
     2041 tatatgataa aagatattat tactattgat gtaggaacaa caaatactag agttagcttg
     2101 tggcgagatg aagaattaca ggaagttttt gtctattcac aaggtgttca gaaagcatca
     2161 ttggcgggga ataatgatac ggtgaaaaaa attttggagt gttcaatcaa aaaattgttc
     2221 aaaaaatata atattttggc ggagaaaaca gtgattatcg cttcaggaat gataacttct
     2281 gcttttggac ttgttgagat tcctcatttg aatgcaccag taggaattca agaattagca
     2341 atatcgatga agcaattttc atttcccgag gtttgcccgc agcctatctg gttcattcct
     2401 ggtgtaaaaa ctcaatgtca agacaagtca cggctttctt cgattcaata tgatgtgatg
     2461 cggggagaag aaacagaggc gatggcagta ttttcattgc tgaaaccgac gatttctgat
     2521 gagcatatct ttgtaatgcc tggaacacat accaagttta tcaaactgga taagaacggt
     2581 aggattgtta aatcaaaaac tgctaccaca ggggagatac tttcattatt gaccaagaaa
     2641 tcgttgatag ctacagatgt tcatcatcgt ttctatgatg aattagatga gtcatatttg
     2701 ttatcaggat ttcattctgc taggagtaac ggtattggca gtgctgtatt tgatgtacgc
     2761 atattggggc aaactcataa tgcttcgcgg aatcagcgag caaattattt gttgggggcc
     2821 gtactttctt cggatatcca actattagaa aattttttag aacccaatga aacagtagta
     2881 ctgactggca aaaaggagct tagagaggcg atacatgtca ttctcaatga cttagataat
     2941 tttagccatc ctatcataat cattgaagct aacgatttag ctggtcgagg tgcattattg
     3001 gctggaaaaa aaaggggatt gttaagaaaa gagggataaa ttaatggaat tggaaaatta
     3061 cccaaaagcg accgctatcc tgcgtggata tacttatgaa gaggcaatgc tagttattcg
     3121 tgttctaagt gagtttaagc attttatagg agtcgaagtt acaacaaata atagtgacca
     3181 cttaaaaatt atccatgatg gaaaaaatag atttggggat aaaatttcga ttggtgttgg
     3241 aacagtcgta actgtcgaac aagcagagga agcaatagaa gcgggtgctg agtttatgtt
     3301 aggcccgcaa aaatttaatg acaaaatttt taaactagct aaaagaaagg gtgttctaac
     3361 aattcctggg gccatgtcgc ccacagagat attcaaaatg tttgagatgg gtgctgatat
     3421 tgttaaggtg ttccccgcca actgtcttgg accggaatat ttcaatcaag tgcaagcccc
     3481 tttaggaagt ttacctttga tggctgtagg aggggtagat cagactaatg cacaaaacta
     3541 tttgaacaat ggagcctctt atgtaggaat tggttcaaaa ttttttgaaa aaagtgctgt
     3601 tcaccaacta aattacgaga ggctaatgga gttggctgaa tcttttatag atagtttaag
     3661 agttgaatag aacccatttg cggaatacaa cttgttttat aatatggcgt tatctgtata
     3721 aaacatagta tcacagtgaa tgagattgaa ctggtagatt gatttttcga ccagttcttt
     3781 ttgcgcgctc tgatgcttga tatattccca acgagataaa aaatccccca agatactaag
     3841 atgaagcgtt tatccaacct catacttaga taaaaaggag gaaatgttct gaatgataaa
     3901 caaaaattag cgcgcacaat ttggcgatga aaaaatcata ttgtatttac gtcaaaatat
     3961 caccatcaaa ttatttatgg aaaacataat aggcataaac ccgattgctc ggctactatg
     4021 tggacacaat tatagtttta aagataagtt tcaattactt attttacacc tcttctttag
     4081 ggataaaact tttcctaacg atcaattttg cgccgattaa tgttttcttt gatatgtccc
     4141 gcgaatatac cagttgatca cttaataaat ctacacaggt tttagctatc tcttcgatat
     4201 ctatcttaaa agttgtaagt ggtggtgcaa cgaattttgc gatgtcgtca tcattaatac
     4261 ttattactgc catatcttta gggatgttaa tacccaattc atggcagccc tgaagaacgc
     4321 cggcagctat agtgtcagat ggtatgaaac atgcctcggg catatcttca tttaactcag
     4381 ctttcatttt aagagttaat tgataccctt cgtcaacagt aaatgatcct tgggagaaaa
     4441 tatacttttc attgagtagt ccgctctttt ctaaatgata tcggaaggca tattcacggc
     4501 tatcaatctc ttctttaccc gtttctaggt taaagaaatt tcctccaata aatccaattt
     4561 ttgtgaaacc ttcattaata aagtagttaa ttgcttgtct ggccatttcg tggaaatcag
     4621 gttctacagt atcgaagtgt tcaggtaatg ggtttattcc tcggattacc cccttatacc
     4681 ctttttgatt taagtagtac aattcctttt ttgtcaattg tcctattgcg ataaatccag
     4741 taatatcgtc aggaatgctt tttacaccat cgtttttaga gatgaaaatc aaatctagat
     4801 tagctttttt actataattt ttcaaatcat ctttgacatg ttgatagtag acatcctttt
     4861 ttaactgttc ctctgagatc caaaaaagaa tggcaatctt gtacagagta gtcttaattt
     4921 ttgtcagatc atatcctaaa gatttggctg taacgattat tttgttttta gtatcagatg
     4981 taatagagag tgactcatca cctttaaaaa gtcttgatat agtagccgtt gagtaaccag
     5041 atttttttgc aatatctcta atagtaacca ttgttcatcc tcctagggat ataataatcc
     5101 ttttctttgt taaagtaaat cgaaactgct cttttagtaa cttaaattac tttttctagc
     5161 aggaaacgaa actctgatat cagcagagag cctaatccat taacagagaa gattgaatcg
     5221 ataatggata gccacttgga gaatgattag taggtgggat tgattttagt gggaatcagt
     5281 ccgttttctt gtttcgtata aattaaatta gtaaaaagat aaatttattt tacgaaaaaa
     5341 cgtttacaaa acggtttttg aatggtatat ttattttaca tcaagggata taagtgcttg
     5401 tatatcgcaa taaaatagat attcgaggtc ggtttttcgt tgtgtaaaaa aatttactta
     5461 tacatgttaa aattatgctg aggtgattta tggattattg gcatattgat caaactaatt
     5521 ttcaaggaga gattaaaatg aattataaaa ctttaccaga agactttatt atgggaggag
     5581 ctacggcagc ttatcaagca gaaggctcta caaaagaagg tggaaaaggg caagtagcgt
     5641 gggatacttt ccttgtagaa aagggacgct atactgctga tccagctagt gatttttata
     5701 atcaatatcc agttgatgct gaattatgca aaaaatttaa aattgatagt attaggatgt
     5761 ctattgcatg gagccgtatt tttccaaaag gctatgggga agtgaaccaa acaggagtgg
     5821 aatattatca taaggtattt gctgaattga ataagcatgg tattattcct tttgtaactc
     5881 ttcatcattt tgatacccct aaagaactat ttgataatgg agatttttta aatcgagaaa
     5941 atgttgaaca tttcgtaaac tatgcacagt tctgtttcga tgaattttct gaggttcatt
     6001 attggagtac atttaatgag atttatccag ttgcttcaaa tcaatatttg atcggatcgt
     6061 tccctccaga agttcaattt gatatagaga agactgtaac ttgtttacac aacatgatgt
     6121 atgcgcacgc aaagacagta aacattttta aagatggtgg atataaaggg gaaattggtg
     6181 ttgttcactc gctagagaca aaatatccag caagtgacaa agaagaagat aagcatgctg
     6241 cgaaattaga tgatgcgtta tcaattaagt tcttattaga tgctacttat ttagggtatt
     6301 actcagatga aacaatggca catattaatg agattttagc agcaaatggg caatctgcag
     6361 atattgattc taatgatttt agagagatga aaaaagcagc aaatcgaaat gattttcttg
     6421 gtatcaataa ctatggtagc cattgggtta aagagtacaa aggagaaagc acacttcact
     6481 acaacactac cggagaaaaa ggtagccaag tctattgcat taaagggatt ggcgagagaa
     6541 tcgtgcgtga ggatcttccg aaaaccgatt gggattggat catttatcca aaagggttat
     6601 atgatttact tgtacgaatc caagacgaat atccaaatta taataaaata tacattactg
     6661 aaaacgggct agggtataag gataattttg aagatgggat tattctagat gatgatcgaa
     6721 tcgattattt acgccagcat tttaatgcga tttccgatgc tatcaaaatg ggagttaatg
     6781 taaaggggta tttcatttgg tcattaatgg atgttttctc ttgggttaat ggatacacta
     6841 agcgttatgg actattctat gtagatttcg atacacaaaa aagatatccg aaagagtctg
     6901 catattggta taaatttgtt agcgaaacaa aaacgataat ataaaaatag ttaggagggc
     6961 aaggaaatgg ataggaaaga attgcaatta ttaggatttg aaattgttgc ttatgcagga
     7021 gatgccagaa gttcattatt aacagtgttg aaggaagtga gaaaaggtaa ttttgataat
     7081 gttgaacgat tattagcgga tgctgatgaa aatttaacct tagcgcataa ctcacaaacg
     7141 aaatgtttag ctgaagaagc gtcagggaac gaaatggaag taggcgtaat ttttattcat
     7201 gggcaagacc atttaatgac aacgattcta ttaagagaac ttatcaatga ttttgttgaa
     7261 ttgtacaaag aaaaatttgc taaagcatag gagaagaaaa atgaatacga ttattaagca
     7321 aattgagaag ggaaaaccgt tttttgaaaa aatctcacgt aatatttatt taggggcaat
     7381 tcgcgatggc tttttaactg ctatgccagc tattctattt tcaagtattt ttattatgat
     7441 tgcggctgtt ccagaagtat ttaacgtgac gttaccagag gcattctcga cgtggctttg
     7501 gaaagtttat ggttattcaa tgggattagt tggtcttttg gttgctgcta caacagctcg
     7561 atgtttagct aattcaatga accgtcaatt atctgattca ggtaagcaga ttaatgaagt
     7621 ttctgttatg ttagcgtcaa tttgtggttt tgtaatgatg gcagctgatc aaattgatgg
     7681 tgggatagct actgattatt tagggacaaa gggattatta gcagctttcg tttctgcgtt
     7741 tgttactgta aatgtgtata aattctgtgt taaaagagat ttgacgatcc gtatgccaaa
     7801 agaagttccc ggaacaatca cacagatgtt tagagatatt atcccctttt caattgcagt
     7861 atttattgcc gttttgattg atacgggagt tcgtcaattt tttggaacat catttgcagc
     7921 aggtgtaatt caattattgc agccattatt tggtgctgct gatggatatg tcggtattgc
     7981 aatcatttgg ggagccatgg caatgttctg gtttgttggt gttcatggac catcgattgt
     8041 tgaaccagcg attgctgcaa ttatttatgc gaacgtagaa actaactttg aattatttaa
     8101 aaacggtgca caagcctcaa aagtattaac agttggtcta ggaaactttg ttggaacgat
     8161 gggtggtact ggagcgacac tagttgttcc ttttctgttc atgttgttcg ctaaatcaaa
     8221 acaattgaaa gcagttggta aagcttcatt tattccagtt tcgtttgcgg taaatgaacc
     8281 gttactattt gctactccta ttattttgaa tccgtacttt ctaattccat ttttattagc
     8341 accaatcgct aacgtatgga tattcaaact ttttgtcgat gtcttgggga tgaatagctt
     8401 tatatccgta ttgccttggg cgacgcccgc accgattggc ttggttttag gaaccgggtt
     8461 tagtgtgttg gcgattgtat tagcggtagt attgattgtt gtcgatgcga ttatttattt
     8521 accttttgtt aaggcctatg attctgaatt agtagaacaa gagttaaaaa acattgctgc
     8581 agaagaagta aaagaagaat tggtcgaaga aatccaagaa gttggtgcaa ctgcggcagt
     8641 tatagttgat gaagcaaaag catcggttgg tgaaggaaag cgcgttttag tactttgtgc
     8701 tggtgccgga acgagtgcaa tgttggctaa tgcattagaa gagggcgcaa aagagacagg
     8761 tgttaatctt tctgctaaag caggagctta tggttctcat tatgatatga tgaaaaattt
     8821 tgatttaatc gttctagcac ctcaagtgaa ttcctatttg gatgatctcc gtaaagatgc
     8881 agacaaatta gggataaaag taattgcaac taaaggtgca gaatatatca atttaacacg
     8941 tgatcctaaa ggagcagttg attttgtatt gaagcaattt tagagcttgc ttagattaat
     9001 aaagcgctag ccaacttagc tagcgtttta tcttaaacac aatggtaagc gctatctttt
     9061 tttgctgttt aaatttcggg tattcttttt gaggacgtcg attgtaaaat taagctagac
     9121 aactaaaaag atcatttgtg ctacactcaa aatagttccg accaaagaat taataaggag
     9181 tgagtacaaa tgacctacac ccatcttaca acagacgaac tagtaatcat agagtcttat
     9241 ttcaatatcg agaaacctgt cgctcttgtc gcacaaagtt taaatcgctc tagacaaacc
     9301 atttataatg tttattcgtt tctcaaacaa ggaaaaaaag tgctagatta ttaccgtcaa
     9361 tacaaacaaa ataaatctcg ttgtggacga cgttcaaccg ttttatctga tgaacaatca
     9421 acatatgttc aagaaaaggt agctcaaggg tggtcacccg atgtgattat cggccgtggc
     9481 gagtttccaa ttgattgttc tgttcgtaca ctctatcgga tgtttaaaaa aggccttttt
     9541 gacacacagt cgttacctat gaaggggaaa cgtaaaccga ataatcatca agaaaagcgt
     9601 ggaaaacagg cctttcgcag aacgattcat gaacggaaca gtctctatcc acacctgact
     9661 aaagaatttg gtcatctcga aggcgacacc attgtgggag ttaaacacaa gagcgctgtt
     9721 attacattgg ttgagtgttt atccaaggtt attattactt tgaaaccgac aggcagacga
     9781 gccgaagata tcgaaaacag gttaaatgat tggttcaaat ccatgcctaa acacttgttt
     9841 aaatccatga catttgattg tggaaaagaa ttttccaact ggcgatctat aagtaactcg
     9901 aacgatattg ccatcttttt cgcagatcca ggaacacctt cgcaaagagg gctaaatgag
     9961 cactcaaacg gcttgcttag acg
//
LOCUS       DAIGTA010000079         9937 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.082, whole genome shotgun sequence.
ACCESSION   DAIGTA010000079 DAIGTA010000000
VERSION     DAIGTA010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.082"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..887
                     /locus_tag="NOB43_002428"
     CDS             <1..887
                     /locus_tag="NOB43_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0983260.1"
                     /translation="DSLETTIIQLYEKGITTREIADLIEKMYGSHYSPTTISNITKMV
                     DEQVTAFHSRPIFHSQYVCLFLDATYIPLRRDAVQKEAVHIALGITSSGEKEILDYLI
                     APQESDIAWSELLGSLVSRGLTDVQLIVADGMTAIQNTCERNYPQAKFQRCLVHINRN
                     IMGKVRISDRQEVASDFKKIHHASTTQEGKEMIQTFIDKWQKRYPRMTHSLQETENLL
                     TFTQFPKAIRGTIYSTNIIESFNKQLKRKTKVKEQFPNEEALDRFLVTQMVAYNNKKA
                     GRAHKGFKQCQDTLDSMF"
     gene            1361..1858
                     /locus_tag="NOB43_002429"
                     /pseudo
     CDS             1361..1858
                     /locus_tag="NOB43_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340950.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(1982..3016)
                     /locus_tag="NOB43_002430"
     CDS             complement(1982..3016)
                     /locus_tag="NOB43_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0983261.1"
                     /translation="MPEPSISVTPIPNTELKKITLKNDELTVVLLNYGARLHQIFAPD
                     NKGHLENVLLSYDELSDVLTDESFFGATVGPVAGRIRNATWGNHQLEKNAGNHHIHGG
                     TNGWSFQYWDVEVFKNPQSIGVVFYLQDTFSDYPGPITATITYQLTANSLEMITKTNS
                     PVETICNPTNHAYFNLSGNGKCDIDTHELAVQAESLLVLDEDKLPTGEQITQADLPIN
                     FKKPHTIEEILNAYPEGLDDVFVLTTPKRSKKVLCLSEKQSGRQLSIATTNRSVVLFS
                     TTGFEADFIINGKHMHSNYGLAIEPQEFPDLVHLPELGSIALYPGQEKVNHTTYQFTI
                     LPNEQIANTQ"
     gene            complement(3009..3674)
                     /gene="pgmB"
                     /locus_tag="NOB43_002431"
     CDS             complement(3009..3674)
                     /gene="pgmB"
                     /locus_tag="NOB43_002431"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI0983262.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYLAWKKLGDEIGIPFDRSFNEQLK
                     GVSREDSLTLLLAHGKKEEQFSKTEFLELAKRKNDYYLEMIQSITPKDVFPGILELLK
                     DLRANNIKISLASASKNGPFLLAKMDLESYFDAIADPAKVANGKPEPDIFLLAAKEIG
                     LTPRDCIGIEDAKAGIAAIIASGAQPIGVGRSEDLGEDIPIVPDTASLTFDYLKKTWQ
                     PNA"
     gene            complement(3667..5961)
                     /locus_tag="NOB43_002432"
     CDS             complement(3667..5961)
                     /locus_tag="NOB43_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI0983263.1"
                     /translation="MKQIKRLFQIDPWKISTNKLDKENLRLQESLTSIGNGYMGMRGN
                     FEEAYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINAVDFIAMDLFIDDQLI
                     DLATLTTEDFYWELNMKNGVLTRSYTVTTPSNKVRLSFERFLSIVKNEAAYIRLTIEM
                     LEGNGTVKVISKLDSNVQNEDSNYDEHFWNDIDHGVKEEIAYLTTKTIPNNFEIEQFT
                     VTAGMRHYVDGKLYTPSYQEGTLAIEGSFTFDLNENETLLIDKEVLIFTSRDIPEAQQ
                     ATHLFKEFNELNVHYPQAKEEQTAAWSKRWELADVVIEGDDEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDIDYL
                     KNEGLEVLAEIARFWADRVHFSKRNNQYMIHGVTGPNEYENNINNNWYTNTIACWVLR
                     YTRENYLKFKEESTAKISDDELAHWQEIAENMYFPVDEELGIFVQHDTFLDKDLKPVA
                     ELSASELPLNQHWSWDKILRSCFIKQADVLQGIYFFNDSFTKEEKQRNFDFYEPMTVH
                     ESSLSPSIHAILAAELGMEDKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLAIV
                     QGFAQMKTDHEQLRFAPFLPKTWSAYSFHINYRGRLLFVAVSNEQVTLNLLSGEALPL
                     EIYKKAYVLTDHLTIPLREGEANV"
     gene            6242..8404
                     /locus_tag="NOB43_002433"
     CDS             6242..8404
                     /locus_tag="NOB43_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0983264.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDL
                     APLVTTGGVIENIGWAIIGNLHLLFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTNEMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAIVWPNVQAGINNFGLWIAESKE
                     SAPILAPFLYGTLERLLLPFGLHHMLTIPINYTQLGGTYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLTNWTPARFKVGQMIGSSGIMMGLALAMYRNVDPDK
                     KSKYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYIVYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGIDLLNFVICVILFGVLTYFVANFLIKKFNYATPGRNGN
                     YDNDSEETPSGSATNADQQIIKIIHLLGGKENIKDVDACMTRLRVSVEDPGKVGSEEE
                     WKRAGAMGLIVKDKGVQAVYGPKADVLKSDIEDLLQSGADIPEPTVEATNKNEKNEEK
                     HVLGIEKELFTVATGEVIALTDVNDPVFSQKMMGDGFAVIPATGEVTAPLSGKIVSVF
                     PTKHAIGMQTAEGAEVLIHMGLDTVHMSQPAFEILVSEGQEVVAGTTIAQMNLDAIKN
                     EGKETTIIVVFTDDKVNGLTINKLGDTERGTVIGKINL"
     gene            8617..9441
                     /locus_tag="NOB43_002434"
     CDS             8617..9441
                     /locus_tag="NOB43_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCI0983265.1"
                     /translation="MKIMTLNTHSWLEEEPQEKLKQIAQKICHEQYDVIALQEVNQTM
                     DAKRLTSEQLKNFSQVQEQTPVRSDNFAYCLIQLLAEQGETYYWSWEMSHIGYAIYEE
                     GNALLSKQPLTSQTHLVSETKEKEDYHTRKILVGQISVKTQCITVASCHFSWWADEKS
                     GFAFEWKELEASLAPLTTPLYLLGDFNNPAEGSGYDLVAKSQLPIRDAYPIAQKKQAE
                     ATIEKRIDGWENNKEGLRIDYIYVPQDCFVTSYQRIFDGENGPIVSDHYGVAVTLE"
     gene            complement(9762..>9937)
                     /locus_tag="NOB43_002435"
     CDS             complement(9762..>9937)
                     /locus_tag="NOB43_002435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983266.1"
                     /translation="IVYELTDIGTPIVKQHNGINEITLYYDLPLFFYFIIGLTFIGWL
                     ILFIMFIRSRIHS"
BASE COUNT         3133 a         1778 c         1997 g         3029 t
ORIGIN      
        1 ttgatagttt agaaacaacc atcattcagc tctatgaaaa aggcattacc actagagaaa
       61 ttgctgattt aattgaaaaa atgtatggct cacattatag tccaactact atttctaaca
      121 tcaccaaaat ggtggacgaa caagtgactg cttttcattc tcgtcctatt tttcattcgc
      181 aatatgtttg tctatttcta gacgcgacgt atattccgtt aagacgtgat gctgttcaaa
      241 aagaagcagt acacattgcc ttaggaatta cttcttctgg tgagaaagaa attttggact
      301 atcttattgc cccacaggaa tcagatattg catggtcaga gttgctaggt agtcttgttt
      361 ctcggggctt aactgacgtc caactcattg ttgccgatgg catgactgct attcaaaata
      421 cctgcgaaag aaattaccct caggcaaaat ttcaacgttg cctagtgcac attaatcgaa
      481 acattatggg aaaagttcgt atttctgatc gtcaagaagt agccagtgat ttcaaaaaaa
      541 ttcatcacgc cagtactact caagaaggta aagaaatgat tcaaactttt attgacaagt
      601 ggcagaaacg ttatcccagg atgacccatt ctcttcaaga gaccgaaaat ctcttgacct
      661 tcactcaatt tcctaaagca attcgaggta ctatctattc cactaatatt attgaatcgt
      721 tcaataaaca gttgaaaaga aaaaccaaag ttaaggaaca atttcctaac gaagaagccc
      781 ttgaccgttt tcttgttaca caaatggtcg catacaataa taaaaaagct ggtagagcac
      841 acaaaggttt caaacaatgc caagacacat tggattcaat gttttaagcg actaatcaaa
      901 ctgaataagg cttaattaat aaatttacac aaacttcttg acacacccta aaataattga
      961 aattacatat tctgatatac atataatatt gatttgattt ctataatgtt taaattattt
     1021 gttacaaagc atctttttat caaaaaaagt cggggctggt tgccaatgct gagaagagta
     1081 aaatcagccg tccgaatgga acaaaatttt tggttttttg cttttgcttt gataaatacg
     1141 caaagaaata tcaattaaag gcgtgggaaa agaactatag ttggaaattt catctaccta
     1201 tctataataa ttctatcttt attaattagt ttaataactt ttatatactc atttacacgt
     1261 tatttaataa gagaccacgg ttaaataaaa atagattata taataagaag gaattaagag
     1321 acatttttaa tttattccga aaagtgaaaa ataaatttct aaaaaacata tcaaattgat
     1381 cgatgaaaat ctaaaaacag attgaaaatc ttttcatgca gaagatatga agaaagctgt
     1441 tgataaggga gacgatttct ctaaattagc caaagacaat aaagtaaaag aagatagcga
     1501 aaaacggaaa agtgaagctt gattcaacta atacaactat tctggtgaca gtcaaagaag
     1561 catcctttaa gttgaaagac ggccaaattt ctgatgtgat cactttcacc aatgattcaa
     1621 cttatgatcc ataaatacta tgtaatcaaa aatggtaaaa aattagaata aaggcaacgg
     1681 aatggataaa tacaaaaaac aattgaaaga aattactact gaaacgaaat tgagcaacaa
     1741 tgaatttcaa aataaagtag tcgataaaat attgaaagac gctaatgtaa aaattaaaga
     1801 caaaaacttt gaaaatgctt tgagtacgtc gaaagtcatt tgtgctcact ccttataatt
     1861 ctttggtagg aactattttg agtgtagcac aaatgacttt tttagttgtc tagcttaatt
     1921 ttacaatcgg cgtaaataaa aatctcttct tttctgagct attcgtaatc aaaacaagca
     1981 actattgagt atttgctatc tgttcattcg gtaaaatagt aaactgatag gtcgtatggt
     2041 tgaccttttc ttgaccaggg tacaaagcga tcgaaccgag ttcaggtaaa tggactagat
     2101 ccggaaattc ttgtggctcg atggctaaac catagtttga atgcatatgt ttcccgttga
     2161 ttataaaatc agcttcaaaa ccagtcgtag aaaataatac cacacttcta tttgttgttg
     2221 ctatagacaa ctggcgtcca gattgttttt ctgaaagaca cagcaccttt tttgaacgtt
     2281 tcggtgtagt aagaacaaaa acgtcatcaa gtccttctgg ataagcgttg agaatttctt
     2341 cgattgtatg tggtttcttg aaattgatcg gtaaatccgc ttgagtgatt tgttcgcctg
     2401 ttggtagttt atcttcatct aataccaata gactttctgc ttggacagcc agttcatgtg
     2461 tatcaatgtc acatttacca ttcccagaaa ggttgaaata ggcatgattg gttggattgc
     2521 agatcgtctc gacgggactg ttcgtttttg tgatcatttc caggctattc gcagttagct
     2581 gatacgtgat cgttgctgtg ataggaccag gataatcgga aaaagtgtct tgtaaataaa
     2641 agacaacgcc gatcgactgt ggatttttga acacttcgac atcccaatat tggaaagacc
     2701 atccatttgt tcctccgtgg atatggtggt tgccggcgtt tttttcaagt tgatgatttc
     2761 cccatgtagc atttcggatt ctgcctgcta cgggaccgac tgtggctcca aagaaacttt
     2821 catcggttaa aacatctgaa agttcatcat aagaaagtaa gacgttttct aaatgtcctt
     2881 tgttatctgg agcaaagatt tggtgaagtc tagcgccata atttagaaga acgacggtca
     2941 attcatcgtt cttcaatgtt atttttttta attcagtgtt ggggatagga gtcactgaaa
     3001 tagaaggttc aggcatttgg ctgccacgtt tttttcaagt aatcgaaagt caatgaagct
     3061 gtatcaggta cgattggaat atcctcccca agatcttctg aacgtcctac gccgataggt
     3121 tgcgcaccac tagcaatgat cgcagcgatt ccagcttttg catcctcgat cccgatgcag
     3181 tcacgagggg tcaaaccgat ttctttcgca gcaagtagaa aaatatctgg ttcaggcttt
     3241 ccattagcga cttttgccgg atcagcaatc gcgtcaaagt agctttctaa atccatcttg
     3301 gcaagtagga aagggccatt tttgcttgca gatgctagtg aaatcttgat attgtttgcc
     3361 cgtaagtctt ttaataattc taaaatccct ggaaaaacat cttttggtgt gatcgattgg
     3421 atcatttcaa gataataatc attttttctt ttcgctaatt cgagaaattc tgtttttgag
     3481 aattgctctt ctttttttcc atgagcaaga aggagagtca gagaatcttc tctgcttaca
     3541 cccttcaatt gttcgttgaa tgaccgatcg aagggaatac cgatctcatc acctagcttt
     3601 ttccaagcaa ggtaatggaa ttcagcggta tctgtaataa cgccatctaa gtcgaataat
     3661 acacctttaa acattcgctt caccttctcg taatggaata gtcaaatgat cagtaagcac
     3721 atacgctttt ttgtagattt ctagcggtaa agcttcgcca gataagaggt tcaatgttac
     3781 ctgttcattt gaaacggcga caaataacaa gcggccgcga taattgatat ggaatgaata
     3841 agcagaccat gttttaggta agaatggtgc aaatcttaat tgttcatgat ctgtcttcat
     3901 ttgcgcgaat ccttgtacga tagcaagcca acttccggtc attgaagtga tgtgtaagcc
     3961 atcctctgta tcattgttat agttatctaa atctaaacga gcagtgcgtt gatacatttc
     4021 aacggctttg tcttccatgc ctagttcagc agctaaaata gcatggatac taggagatag
     4081 ggaagactca tggacagtca ttggctcgta aaaatcaaag ttgcgttgtt tttcttcttt
     4141 tgtaaatgaa tcattgaaga agtagatacc ttgtaaaacg tctgcttgtt taatgaagca
     4201 agaacgaagg atcttgtccc atgaccaatg ctgattcaat ggcaattcac ttgcggatag
     4261 ttccgctact ggtttgagat ctttgtctaa gaaagtatcg tgttgaacaa aaatccctaa
     4321 ttcttcatct actgggaagt acatattttc agcaatttct tgccaatgtg ccaattcatc
     4381 gtcgctgatt ttagcagtgc tctcttcttt gaacttcaaa taattttctc gtgtgtaacg
     4441 tagtacccaa caagcaatcg tattcgtgta ccaattgttg ttgatattat tctcatattc
     4501 gttcggtcct gtaaccccgt ggatcatata ttgattgttt cgtttagaaa aatggactcg
     4561 gtctgcccaa aagcgagcga tttctgctaa gacttctaaa ccttcatttt ttaaatagtc
     4621 gatgtcgcca gtgtagttag tataattata aatagcgtag gcaattgcgc catttcgatg
     4681 gatttcttca aaggtgattt cccattcatt gtggcattcg acacctgtga aagtgaccat
     4741 tggatataac gcgcccttta gcccttgctg ttgtgcatta tggattgctt gtggcaattg
     4801 gttatggcgg tacttcaaga gattcttagt gacttcaggt ttcgctaaag cgaggtacag
     4861 aggcactgca taggcttcag tatcccagta agttgcacca ccatattttt cgccagtgaa
     4921 gccttttggt ccaatattca aacgttcatc ttcgccataa taagtagaaa atagctggaa
     4981 gaggttgaaa cggattcctt gttgtgcttc atcgtctcct tcaatgacta catctgccaa
     5041 ttcccatcgt ttagaccaag cggctgtttg ctcctctttt gcttggggat agtgaacgtt
     5101 caattcgttg aattctttaa agagatgtgt cgcttgttgc gcttcaggga tatctcggct
     5161 tgtgaaaatc aatacttctt tgtcgataag aagtgtttca ttttcattta agtcaaaggt
     5221 gaatgaacct tcgattgcta aggtgccctc ttggtagctt ggcgtatata attttccatc
     5281 aacgtagtgg cgcatcccag cggtcactgt aaattgttcg atctcaaaat tattcgggat
     5341 cgttttagtc gttaagtacg ctatttcttc cttgacgcca tgatcgatgt cattccaaaa
     5401 gtgttcatcg taattgctgt cttcgttttg gacattgcta tctagcttag aaataacttt
     5461 tacagttcca tttccttcca acatctcaat ggttaagcga atataagcgg cttcattttt
     5521 gacaatactt aaaaagcgct cgaatgaaag acgaactttg tttgatgggg tagtgactgt
     5581 ataactacgt gtcaaaacac cgtttttcat gtttaattcc caataaaaat cttcagtagt
     5641 aagtgtagct agatcaatca gctgatcatc gataaaaaga tccatagcga taaaatcgac
     5701 tgcattgatt acttttccaa aatattcagg atagccgttt ttccaccagc caacacgtgt
     5761 tttgtcaggg taccaaacac ctgctaaata ggttccttgg tgatgatcac cagaatatgc
     5821 ttcttcaaaa tttccgcgca tacccatata tccgttaccg atactggtca atgattcttg
     5881 caagcgtaaa ttttctttat ctaatttatt cgtgctgatt ttccaagggt cgatctgaaa
     5941 taaccgttta atttgtttca ttgttctcct cctagacgtt gtcgtttata cgtccataat
     6001 aaacgcaacc gattgcgtaa gtcaactaga aaagtgaaat taaattttga agtggatgaa
     6061 aaaacaaaac aaaagcgatt ttatcaatat ttactactat aatatgaaca gaaataatgt
     6121 ataaagaacg attgggtact tacagaaaaa gcataaaaat acgaaataaa gcatttacaa
     6181 aaaaagaaat acacgctata ataactaaca acgaaaccga ttgcacaaag gagacgagga
     6241 aatgaaaaaa atatttagct ttgagttttg gcaaaaattt ggaaaggctt taatggtcgt
     6301 tgtggcagtt atgccagcgg caggtttgat gatcagtatc ggtaaatcga ttccgttgat
     6361 caatcctgat cttgcacctt tagttacaac gggtggcgtg atcgaaaata ttggttgggc
     6421 aattatcgga aatttacatc ttttatttgc actagcgata ggtggtagtt gggcaaaaga
     6481 acgagcaggg ggagcattcg ctgcggggat ctcatttata ttgatcaatc ggatcacagg
     6541 agcaattttt ggtgtgacta atgagatgtt ggcaaatgaa gacgcattta cgcatacctt
     6601 gtttggcacg aaaatcatgg ttaaagggtt ctttaccagt gtattagaag caccagcact
     6661 aaatatgggg gtatttgttg ggattattgc agggttcgtt ggggcgatgg cctataataa
     6721 atattacaat tatcgtaaat tacctgatgc attatcgttc tttaatggaa aaagatttgt
     6781 tccttttgta gttattttgt ggtcaacgat tgttgcattg attcttgcta ttgtatggcc
     6841 gaatgtccaa gcagggatca ataactttgg attgtggatt gcagagtcaa aagaaagcgc
     6901 tccgatttta gcaccattcc tatatggtac attggaacgt ctattgttac catttggctt
     6961 acatcacatg ttgacgatcc caatcaatta tacgcagctg ggtggtacct atgagatatt
     7021 atctggtgcg caagcgggaa cacaagtatt tggacaagat cctttatggt tggcgtgggc
     7081 gactgatttg gtcaacttga aaggcgccgg cgacatgtcg caatatgaat tcgtattaac
     7141 gaactggaca cctgctcgtt ttaaagtggg acaaatgatt ggttcttccg gtatcatgat
     7201 gggattagca ctagcgatgt accgtaatgt tgatccagac aaaaagtcta aatataaatc
     7261 aatgtatttt tcagcagcac ttgcagtttt cttaacaggt gtaaccgaac cattagagtt
     7321 catgttcatg tttgcagctg tacctcttta cattgtttat tctgtgatcc aaggggcagc
     7381 ttttgcaatg gcagatattc tacctttacg tgtccattca tttgggaaca ttgaactatt
     7441 gacacgtaca ccattagcga tcaaagcagg attaggtatc gacttgctca attttgttat
     7501 ctgtgtcata ttatttggag tattgacgta ttttgtggca aactttttga tcaaaaaatt
     7561 caattatgct acaccaggac gtaatgggaa ctatgataac gacagtgaag aaacgccgtc
     7621 aggttctgca actaatgcag atcaacaaat cattaagatc atccatttgt taggtggaaa
     7681 agaaaacatc aaggatgtag atgcttgtat gactcgttta cgtgtcagcg tcgaggatcc
     7741 tgggaaagtc ggttcagaag aagaatggaa acgtgctgga gcgatgggct tgatcgttaa
     7801 ggacaaaggt gtgcaagccg tgtatggacc aaaagcggat gtgttgaaat cggatattga
     7861 agatttacta caatcaggcg ctgatattcc agagccaaca gttgaggcaa caaataaaaa
     7921 tgagaagaat gaagagaaac atgttttagg tatcgaaaaa gaattattca ctgtagcaac
     7981 tggtgaggta attgctttaa cagatgtgaa tgatccagtc ttttcacaaa agatgatggg
     8041 tgatggcttt gctgtcattc ctgccaccgg agaagtgacg gcaccacttt ctggtaaaat
     8101 cgtgagtgtc ttcccaacca agcatgcaat tggcatgcaa acagcagaag gagcagaagt
     8161 tttgatccat atgggactgg atactgttca tatgagccag ccagcgtttg agatcttagt
     8221 ttctgaaggc caagaagtag ttgcaggaac aacgattgct cagatgaatc tagatgcaat
     8281 caagaacgaa gggaaagaaa cgacgatcat agtagtcttt acagatgaca aagtcaatgg
     8341 gctgaccatc aataaattag gagacactga acgaggaaca gtgatcggga aaataaactt
     8401 gtaaagaatc acagaagttc atgtgtgtat ttcatatcga aagaatgtgt tcgatgtgtg
     8461 taactcctag aagtaagccg ataatcccga aattgctttt cctatttcag ggattattgg
     8521 cttatttttt gaataaacta ctttgggatc tttacctata tggatccaga aggtgggagc
     8581 aatgtttcga cccatcccat taagaaggag aattatatga aaataatgac gttgaacacg
     8641 catagttggt tagaagagga accacaagaa aaattaaaac agatcgctca aaaaatctgt
     8701 catgaacaat atgatgtgat cgcattgcaa gaagtcaatc aaacgatgga cgcaaaacga
     8761 ctaaccagtg agcagctgaa gaattttagt caggtgcagg aacaaacgcc tgtccgctcg
     8821 gataactttg cctattgctt gatccagctc ttagcagaac aaggtgaaac ttactattgg
     8881 agttgggaaa tgagtcatat cggctatgct atctatgagg aaggcaatgc gcttctttcc
     8941 aaacaaccac taactagtca aacgcaccta gtctccgaaa caaaagaaaa agaggattac
     9001 cacactcgaa aaatattagt aggtcaaatc tctgtcaaaa cacaatgtat tactgtagca
     9061 agttgtcatt tttcttggtg ggcagatgaa aaaagcggat ttgcatttga gtggaaagaa
     9121 ttagaagcaa gtttagcgcc tcttacaaca ccactgtatc tattagggga tttcaacaat
     9181 cctgctgaag gcagcgggta cgatttagtg gcaaaaagtc agttgcctat tcgtgatgct
     9241 tatccaatcg cgcaaaaaaa acaagctgaa gcaacgatcg aaaagagaat cgatggctgg
     9301 gaaaacaata aagaggggct acgtatcgac tatatttatg taccacaaga ttgctttgtt
     9361 acaagttatc aacgtatttt tgacggggaa aatggcccga ttgtcagtga tcattatggg
     9421 gtagcagtca cgttggagtg aagagaaacg aaggaatatt gtcacaataa gaatatggga
     9481 caaatctaaa aaccaggttt gctacagact ctcgaataaa cgacgggagc agaagcaact
     9541 ccctcttaaa taagccgaaa tgaacaaaaa tttgaaaagc aattttcgtt catttcttct
     9601 tatttctcag agttaaacac ttctgtccta acctctctca aataaacgac gtccgaaagg
     9661 caggtttttc ggaaatttaa aaaaaacgag caatacaaaa aatgtattgt tcgttttttc
     9721 tctaatttct cataaacgat ttttgtctag acctcatttt tttatgaatg tatccgactt
     9781 ctaataaaca tgatgaataa aatcagccaa ccaatgaagg tcaacccgat gatgaaataa
     9841 aagaagagcg gcaagtcata atataaggtg atctcattga taccattatg ctgtttgacg
     9901 attggcgtac cgatgtctgt caattcatat actatgt
//
LOCUS       DAIGTA010000080         9826 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.083, whole genome shotgun sequence.
ACCESSION   DAIGTA010000080 DAIGTA010000000
VERSION     DAIGTA010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.083"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..658)
                     /locus_tag="NOB43_002436"
     CDS             complement(<1..658)
                     /locus_tag="NOB43_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0983267.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     K"
     gene            complement(663..1430)
                     /locus_tag="NOB43_002437"
     CDS             complement(663..1430)
                     /locus_tag="NOB43_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0983268.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1920..2345
                     /gene="lacA"
                     /locus_tag="NOB43_002438"
     CDS             1920..2345
                     /gene="lacA"
                     /locus_tag="NOB43_002438"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HCI0983269.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2362..2877
                     /gene="lacB"
                     /locus_tag="NOB43_002439"
     CDS             2362..2877
                     /gene="lacB"
                     /locus_tag="NOB43_002439"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HCI0983270.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2888..3820
                     /gene="lacC"
                     /locus_tag="NOB43_002440"
     CDS             2888..3820
                     /gene="lacC"
                     /locus_tag="NOB43_002440"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HCI0983271.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3823..4803
                     /gene="lacD"
                     /locus_tag="NOB43_002441"
     CDS             3823..4803
                     /gene="lacD"
                     /locus_tag="NOB43_002441"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI0983272.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPAIKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4831..5148
                     /locus_tag="NOB43_002442"
     CDS             4831..5148
                     /locus_tag="NOB43_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0983273.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5148..6854
                     /locus_tag="NOB43_002443"
     CDS             5148..6854
                     /locus_tag="NOB43_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0983274.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7001..8407
                     /gene="lacG"
                     /locus_tag="NOB43_002444"
     CDS             7001..8407
                     /gene="lacG"
                     /locus_tag="NOB43_002444"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI0983275.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8530..8703
                     /locus_tag="NOB43_002445"
     CDS             8530..8703
                     /locus_tag="NOB43_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HCI0983276.1"
                     /translation="MKLPPLLKCGKWYVLTGKEWICHSDLELSAFEWEFLQSLDVEIR
                     ETIHFEVNYLPFQ"
     gene            8724..9623
                     /locus_tag="NOB43_002446"
     CDS             8724..9623
                     /locus_tag="NOB43_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCI0983277.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNCPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDKL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3094 a         1666 c         1976 g         3090 t
ORIGIN      
        1 gtttatgacg acttttggaa gtaaaaatcc atccattatc tttataatca ggattgaatc
       61 ttatatgttg gtgatttaac tcaatttcct ctttaagaat ttctatagcc cttttagata
      121 attggacatt ttggtaactt tgtaagtttt ttacattacc ttcatagcta ttttctgcag
      181 ctcctccgtg agtggactga ctaatgatga tattttgctt ttcaaaatat tgataggcac
      241 caatattttg gagttttcga ctctgtaagt caacagggcc attagttaga atacctattg
      301 ggatgcggtt tttatgtaga gccagcagta gttgatgtat ctcaggaatc atcgtaatct
      361 gatcgagttc atattcatag tcagcttgga agtctagagc ttctgtccta gaaatactat
      421 cgatgccaaa ttcttccata gtcttctgac agcgaaaaat tctaagctgc tcaatactga
      481 tgagtttttt cgtgtattta ggaaaagcaa catcagacca acatctgaaa cgtttgtaaa
      541 tgttatctat ttgttggata tcaatcgttg gaaaacattt ctcaacgcta cgtttaaagg
      601 ggagttgatg gtcataaaga gtgtcatcaa ggtcaaaaac aatattttta taagtcataa
      661 ttctagtccg cttttaaaat agtagtgtac tggctaaatt cctctaagtg ttgagggcta
      721 atctggttat ctgtaatgat ggtatcgagt tgatctagat tatagaagtt aaagaaatcg
      781 tatcgatcga atttagtact gtctactaat aagaattttt ctacagcatt gtttagggca
      841 agttgttgaa tcacaccttc cttgtcacta tatgtagcaa tagaattatg ggtaacagca
      901 tttgcactaa caaaagcttt ggcaaatcta attgctttta aatttgtcga agccattgaa
      961 cctacaaaag ctccagttat ttctctatat tcaccgccaa gaagcaataa atcaatggtt
     1021 tcgctatcat ttagaatcaa gaacacaggg agactatttg taatgacacg aattttataa
     1081 cctttacgac ctttcaattc taatgccagt tgttcaagtg tagttccggg tccaataaaa
     1141 atagtatcgc catctttgat taaagagcag gcttttttag caatgtcaat tttttctttt
     1201 gtatttagac ttttcttctc gatatgtgtc ttttcaagtg gctttttaga ggaaagcaat
     1261 tgtgcaccac catgagtacg tgttaaaagt ccatcagctt ctagagcatc aaggtctcta
     1321 cgggctgtca tatcggaaat atctagttca tctattattt cttttatggt tatggtccca
     1381 tcaatcttta acatatctaa aattttttct aatcgtcgtt ttttgttcat atgaagaccc
     1441 ttctttcata aagtaatttt tttccaaaga taattctctt ttaattgtat cataaaagac
     1501 aatattttca aggtaaaaca aacaatttca aacaaaaaca aatgttagat gatgaaataa
     1561 gaacagtgga ttgacgtata ttagcttagg tcagattttg tataagacga aaataaagta
     1621 ggacctctta atcagtaagt tatagaaagt aaaagacttt tgtaatactt gaatagatat
     1681 ttcacgtcca ttttgtgatg gattaaatga acaaaaatga acaataattt aacggtgtta
     1741 tctatttttt aaaaaaacaa ataaaaaaaa caaaaaataa acaaaaaaag tgttgctttt
     1801 tgtttgaatg cttgatatta tataaacaaa gaaatgatga aaacgttttt tcgaacattt
     1861 tgcaaaatgt tttctacttc tacgtagcat ttctttctaa aatttaggag gtggtcaaaa
     1921 tggctattgt tgttggtgca gatctcaaag gtacgagatt aaaagatgtt gtgaaaaatt
     1981 ttcttgtaga agaaggtttt gaggtaattg atgtgactaa ggacggacaa gattttgttg
     2041 atgttacctt ggcagttgcc tctgaagtaa ataaagatga gcaaaactta ggtattgtaa
     2101 ttgatgctta tggagctggt ccattcatgg tagcaactaa aattaaaggt atggttgcag
     2161 cagaagtttc agatgaacgc tcagcttata tgacacgtgg acataacaat tcacgaatga
     2221 ttacggttgg cgctgaaatc gtcggtgatg agcttgctaa aaacatcgct aaaggtttcg
     2281 tcaatggtaa atatgatggc ggacgtcatc aaatccgagt agatatgctt aacaaaatgt
     2341 gttaagaaaa ggagttaagg aatgagaatc gcaattggat gtgaccacat tgtcacagat
     2401 gaaaaaatgg cagtatcaga attcttgaaa tcaaaaggac atgaggtcct tgatttcggg
     2461 acatatgacc acgcacgtac tcactaccct atctatggta aaaaagtcgg tgaagcagta
     2521 gtaagtggtc aagcagactt gggagtatgt atctgtggta caggtgtcgg cattaacaat
     2581 gcagtcaata aagttccagg tgttcgctca gcgttggttc gtgatatgac atcagctata
     2641 tatgcaaaag aagagttaaa tgcgaatgtt atcggtttcg gtggaaagat tactggtggt
     2701 cttcttatga atgacatcat tgaagctttc attgaagctg agtacaaacc aacagaagaa
     2761 aataaaaaat tgattgcaaa aatcgaacac gttgaaacac ataatgcaca tcaagcagat
     2821 gaagatttct ttacagaatt ccttgaaaga tgggaccgtg gtgactacca cgattaaggt
     2881 ataacaaatg attctgacag tcacactaaa tccttcagta gacatctctt atcctctaga
     2941 aacattgaaa attgatacag tgaatagggt gaaagatgtt agtaagacag ctggtggaaa
     3001 aggcttaaat gttactagag tcttgtatga atctggtgat aaagttactg ctacaggttt
     3061 cttaggtggt aaaattggtg aatttattga aagcgaatta gaacaatctc ctgttagtcc
     3121 agctttttat aaaatctcag gaaacactag aaactgtatt gctatcttac acgagggtaa
     3181 ccaaacagaa attttggaac aaggaccaac aatttctcat gaagaagcag aaggctttct
     3241 tgaccactat agcaatctta ttaaacaatc agaagttgtg acaatttcag gaagtttacc
     3301 ttcaggactt cccaacgatt attatgaaaa acttatccaa cttgcttcgg atgaaggagt
     3361 agcagtcgtt ttggattgtt caggtgcacc tcttgaaaca gttctaaaat cgtcggctaa
     3421 acctactgcc atcaaaccta ataatgagga actttcacag ttgcttggaa aagaagtaac
     3481 aaaagatatt gaagaactca aagacgttct taaagagtca ctttttagtg gtatcgaatg
     3541 gatagtggtc tcattaggtc gaaacggtgc ctttgcaaaa catggtgatg ttttctataa
     3601 ggtagatatt cctgatatcc cagttgttaa tccagtcgga tcaggggact caacggtagc
     3661 tggtattgca tcagctttaa atagtaaaaa aagtgacgct gacttattaa aacatgcgat
     3721 gacattgggt atgttaaatg ctcaagaaac aatgacaggg catgtgaata tgactaatta
     3781 cgaaacacta aactcacaaa ttggagtaaa agaggtataa aaatggtact tacagaacag
     3841 aaacgcaaat ctttggaaaa aatttcagat aaaaacggtg ttatctcagc tttggcattt
     3901 gaccaacgtg gtgctttgaa acgtttgatg gcacagtatc aagatacaga accaactgta
     3961 gctcaaatgg aagaactaaa ggttttggtt gctgatgaac ttacaaaata cgcttcttca
     4021 atgttgcttg accctgaata tggacttcca gcaataaaag cattggataa agaagcaggt
     4081 cttcttcttg cctatgaaaa aacaggttat gatacatcaa gtacaaaacg tttgcctgac
     4141 tgcttggatg tttggtctgc aaaacgtatc aaagagcaag gcgctgatgc cgttaagttc
     4201 ttgctttact atgatgtaga cagctcagat gaacttaacc aacaaaaaca agcttatatt
     4261 gaacgtgttg gttctgaatg tgtcgctgaa gatattcctt tcttcttgga aatccttgct
     4321 tatgatgaag aaatctcaga tgcaggttct gttgaatatg caaaagtgaa acctcgcaaa
     4381 gtcattgaag cgatgaaagt tttctctgat ccacgcttta acattgatgt tcttaaagta
     4441 gaagtaccag ttaacgttaa atatgtcgaa ggttttgctg atggtgaagt ggtttacagt
     4501 aaagctgaag ctgctgactt ctttaaagca caagaagaag cgactaacct tccatacatc
     4561 tacctaagtg caggtgtatc tgctaaattg ttccaagaaa cattgcaatt tgctcacgac
     4621 tcaggtgcca agtttaatgg tgtgctttgt ggacgtgcta cttgggcagg atctgtagaa
     4681 ccttacatca aagaaggtga aaaagcagca cgtgaatggt tgcgtactac tggattcgaa
     4741 aatattgatg aacttaacaa agttcttgtt aaaacagcta gtccatggac tgataaagta
     4801 tagtaaaaac ataaaacgga ggatattgtt atgaacagag aagagatgac tctcttaggg
     4861 tttgaaattg ttgcttatgc tggagatgct cgctctaaac ttttagaagc gcttaaagcg
     4921 gctgaaaatg gtgatttcgc taaggcagat agtcttgtag tagaagcagg aagctgtatt
     4981 gcagaggctc acaattctca gacagctatg ttggctcgag aagcttctgg ggaggaactt
     5041 ccatacagcg ttaccatgat gcatggtcag gaccacttaa tgactactgt cttattaaaa
     5101 gatgtgattc atcacctcat cgaactttat aaaagaggag caaaataatg cataaactca
     5161 ttgaacttat tgagaaaggg aaaccgttct ttgagaaaat ctctcgaaac atctatcttc
     5221 gtgctattcg tgatggattt atcgctggta tgccagtcat ccttttctca tctatcttta
     5281 tccttattgc ctatgtccca aatgcttggg gattccactg gtcaaaagac attgagacct
     5341 tcttgatgac tccttatagc tattcgatgg gtatcctagc attctttgtt ggtggtacta
     5401 ccgctaaagc tttgacggac tcaatgaacc gtgacctacc tgcgaccaat cagattaact
     5461 tcttatctac gatgctagcg tctatggtag ggttcctttt gatggcagct gagcctgcaa
     5521 aagaaggagg cttcttgaca gccttcacgg gaacaaaagg tcttttgaca gcatttattg
     5581 cagcctttgt gacagttaat gtttacaagg tctgtgtgaa aaataatgtt actattcgta
     5641 tgcctgaaga ggttccacca aatatctctc aagtatttaa agacttgatt ccattcactg
     5701 tagcggttgt tctcctttat ggatttgaac tcattgttaa gggaactctt ggtgtaaccg
     5761 ttgcagaatc aatcggtacc cttcttgctc ctctcttctc agctgcagat ggttaccttg
     5821 gaattacact gatctttggt gcttatgcct tcttctggtt tgttggtatc cacggtcctt
     5881 caattgtcga accagcaatc gctgctatca cttatgccaa tatcgatgcc aacttgcatc
     5941 ttatccaagc tggacaacat gcagataaag ttatcacttc tggtactcaa atgtttattg
     6001 ttaccatggg tggaacagga gctacattga ttgttccatt cttgttcatg tggatttgta
     6061 aatcagaacg taaccgtgcc atcggacgtg cctcagttgt tccaacattc tttggggtta
     6121 atgagccaat cttatttggt gcaccaatcg tattgaatcc gattttcttt gtaccgttca
     6181 ttttcgctcc gattgtcaac gtttggatct ttaaattctt tgttgacaca ttgaacatga
     6241 actcattctc tgccaacctt ccatgggtta ctcctggtcc gttgggaatt gtactcggta
     6301 ctaacttcca agttctatca tttatcttag ccggactctt ggtagttgtt gatactatca
     6361 tttattaccc atttgttaag gtatacgatg aacaaattct tgaagaagaa cgttctggta
     6421 aaacaaacga tgctcttaaa gaaaaagtag ctgcaaactt caatactgct aaagcagatg
     6481 ccgttcttgg aaaagcaggc gttgctaaag aagatgtagc agcaaacaat aatatcacaa
     6541 aagaaactaa tgtccttgtt ctttgtgcag gtggaggtac aagtggcttg cttgccaatg
     6601 ccttgaacaa agcagcagca gaatacaatg ttccagtcaa agcggcagcg ggtagttatg
     6661 gtgctcaccg tgaaatgttg ccagagtttg acttggttat cttggctcca caggtcgctt
     6721 caaacttcga tgatatgaag gctgaaacag ataaattggg cattaaactt gcaaaaactg
     6781 aaggagctca atatatcaaa ttgacacgtg atggacaagg tgctcttgca tttgttcaac
     6841 aacagtttga ttaataaatt tgtaaaagtt atttgagacg agattattct ttcagttcct
     6901 tataatattg ttaaccatat cattgcattt catttcattt ccttggtttc cggaactcag
     6961 aatatcgtct caaatgcttt ttttgaaagg atttatagtt atgactaaaa cactccctaa
     7021 agattttatt tttggtggtg ctacagctgc ttatcaagca gaaggtgcga ctcacacgga
     7081 tggtaaaggc ccagttgcat gggataagta tcttgaagac aattattggt acacagcaga
     7141 gcctgcaagt gatttttacc ataaatatcc tgttgattta gaattagctg aaaaatatgg
     7201 cgttaatggt attcgtattt caattgcctg gtctcgtatt ttcccaactg gctatggcga
     7261 agtaaatgaa aaaggtgttg aattctacca taatcttttt gccgagtgcc acaaacgtca
     7321 tgttgagcca ttcgtgactt tgcaccactt tgacacacca gaagttcttc actcagatgg
     7381 agatttctta aaccgcgaaa atatagaaca ctttgtagat tatgccgctt tctgttttga
     7441 agagttccca gaagtaaact actggacaac tttcaatgaa attggcccaa ttggagatgg
     7501 tcaatacttg gttggtaaat tccctccagg cattcaatat gatcttgcca aagtcttcca
     7561 atcacaccac aatatgatgg tttctcatgc acgtgctgtg aaattgtata aagataaagg
     7621 ttataaaggc gaaattggtg tagtacatgc gttgccaacc aaataccctt atgatccaga
     7681 aaatccagca gatgttcgtg ccgctgagtt agaagatatc atccataaca aatttatctt
     7741 ggatgcaacc taccttggac actattcaga taaaacgatg gaaggggtca accacatcct
     7801 agctgaaaat ggtggagaac ttgatcttcg tgatgaagac ttccaagcac ttgaagcagc
     7861 taaagatttg aacgatttcc ttggtatcaa ctactacatg agtgattgga tgcaagcctt
     7921 tgatggtgag actgaaatca ttcacaatgg taagggtgaa aaaggaagtt ctaagtacca
     7981 gattaaaggt gttggtcgcc gaatcgcacc agattatgtg cctagaacgg attgggactg
     8041 gattatttat cctgaaggct tgtatgacca aatcatgcga gtgaaaaatg attatccaaa
     8101 ctacaagaag atttacatca ctgaaaacgg tcttggatac aaagatgagt ttgtagataa
     8161 taccgtttat gatgatggtc gtattgatta cgtgaagaaa cacttggaag ttttatcaga
     8221 cgcaattgcg gatggtgcaa atgttaaagg ttacttcatc tggtcactta tggatgtctt
     8281 ctcatggtca aacggatacg aaaaacgtta tggactattc tatgtagact ttgacacgca
     8341 agaacgctat cctaagaaat cagctcattg gtataagaaa gtagcagaaa ctcaagtgat
     8401 agagtaatat tacttgaaaa tgtaaaaaat tgttatccga tactttagaa aaagtacaac
     8461 acttatttag accaggcttt gaaaaggtat atattgttag tttcgaagat tgtcctatga
     8521 ttcctgagct tgaagctacc cccgttgcta aaatgtggta aatggtatgt tttaactgga
     8581 aaagagtgga tttgccattc tgatttagag ttatcagcat ttgaatggga atttttacaa
     8641 tcactcgatg tagaaatacg tgagactatt cacttcgagg taaattattt gcctttccaa
     8701 taataaaaag aaaggaatta gttgtgacta tcgaattaaa aaacgagtat cttactgttc
     8761 agtttaaaac acttggtggt caactgactt cgattaaaga caaggatggg atagagtatc
     8821 tctggcaagc tgatccaaat tattggaatg gacaggcgcc tattctattt cctatctgtg
     8881 gtagtttacg aaatgattgg gctatttata gacctcaaga aagacctttt tttacaggtc
     8941 ttattcgtag acatggtttt gttcgaaaag aagaatttat tctggaagaa gtcaatgata
     9001 atagcgtgac ctttagtatt aaaccaaatg ctgagatgct tgataattac ctatatcagt
     9061 ttgaactgag agttgtttat accttgaatg gtaaatcaat tagaaccgaa tttcaggtaa
     9121 cgaacttgga aatggaaaaa acaatgcctt actttattgg agcccatcca gcattcaatt
     9181 gtcctttagt agaaggtgaa aactatgagg attattatat tgaatttagt gaggttgagt
     9241 cttgctcgat accaaagagt tttcctgaga caggattatt agatttgcaa gatcggacac
     9301 cttttttgga aaatcaaaag attctcgatt tggactactc acttttttcc catgatgcca
     9361 ttacacttga caagctcaag tctcgtagcg taacgcttcg gtcaaggaag tctggtaaag
     9421 gtcttcgagt agattttgat gattttccga acttgattct gtggtctaca actaataaaa
     9481 gtccattcat tgctttggaa ccttggagtg gtctctccac ttcacttgaa gaaggtaatt
     9541 tcttagaaga taaaagacag gtaacgaaaa tttcacctca agaaacttct agaaaaatct
     9601 atgatattac tatccttaat taaaatttgt tattatttga gtcttcaata agaattgaat
     9661 actcttacct tgtgatgata gattggtctt ctccgtgcca gtcttacatc gcaaggtttt
     9721 taagtttttt gtgggtctat gtcaactgta gtgggtgacg aaaagctaac atctaaagac
     9781 agtctggtag taaaaaaata agattattta ctacttcttg atttaa
//
LOCUS       DAIGTA010000081         8730 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.084, whole genome shotgun sequence.
ACCESSION   DAIGTA010000081 DAIGTA010000000
VERSION     DAIGTA010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.084"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..191)
                     /locus_tag="NOB43_002447"
     CDS             complement(<1..191)
                     /locus_tag="NOB43_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0983278.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWK"
     gene            519..746
                     /locus_tag="NOB43_002448"
                     /pseudo
     CDS             519..746
                     /locus_tag="NOB43_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            872..1843
                     /locus_tag="NOB43_002449"
     CDS             872..1843
                     /locus_tag="NOB43_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0983279.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            1984..3297
                     /locus_tag="NOB43_002450"
     CDS             1984..3297
                     /locus_tag="NOB43_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI0983280.1"
                     /translation="MKRRMLAIAAILALTAGGLAGCGSKEKSSGSSDSGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFVWSNGGDVVNADGTKAEDYFNDKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMLLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIISLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQISGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            3340..4206
                     /locus_tag="NOB43_002451"
     CDS             3340..4206
                     /locus_tag="NOB43_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0983281.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQLGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            4203..5051
                     /locus_tag="NOB43_002452"
     CDS             4203..5051
                     /locus_tag="NOB43_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0983282.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            5065..6537
                     /locus_tag="NOB43_002453"
     CDS             5065..6537
                     /locus_tag="NOB43_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HCI0983283.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWINDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMTAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKGLVYDQHYLRLEINLKQATKLELHYAKGPHHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            6554..7426
                     /locus_tag="NOB43_002454"
     CDS             6554..7426
                     /locus_tag="NOB43_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0983284.1"
                     /translation="MIYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(7660..8648)
                     /locus_tag="NOB43_002455"
                     /pseudo
     CDS             complement(7660..8648)
                     /locus_tag="NOB43_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2662 a         1523 c         1827 g         2718 t
ORIGIN      
        1 tttttccaaa tttgatagag tagtttgcca tattcttgca cccaacgata aatcgtcgta
       61 tgagaaacgt taatgccacg atcatataag atttcttgaa cttcacgata gctaaggtta
      121 taacgaagat agtatcccac ggctacaata atcacatcct gctgaaattg ctttccttta
      181 aaatgattca tcgtcattcc tcctgctatc tttttctatt attctacctt atttgatagt
      241 agatttaaaa ctttgcaaca gaaccacatt aattttgttg gcaaatatag tttccgctat
      301 gaaaaagaat tatcgaatgg aatactacgt ccgttaaata tagagaatta ttgagaatgt
      361 tcgtcttttg gttcctaccg tgcattttcg cacggatgtt ccagatacta tttttgaatg
      421 tataaaattg aaaacacaag aatcctatta aatcaacgat tcttgtgttt ttaatttttc
      481 actaccgtgc attttcgttt ctatgttcca tgtaccccaa tcttgaaaaa ttaattaaag
      541 acttatataa agccattgac gacttagtcg tggtgctacc ggagtatcaa tgtttaacca
      601 gtatcccagg tattggtcct gtttaggctg ctggaatact cgctgaaatt ggtccaattg
      661 aacgtttttc tgatgaaata aaattgacaa agtatgccgg cctatattgg cgacagagtc
      721 aatccggtaa atctgaatac gaaaattttt ttacgaaaag cttcacgtct aatatctatt
      781 ttaaaataaa aatattcctg ctaatttgga atcgtttcct tcttttggta taataatacc
      841 tgaaattctt ttgagaggag ttgttcgtga agtgaaaact actatgaagg atgttgctgc
      901 gttagcagga gttggtgtgg gtacggtatc tagagtaata aatggagtaa aggtgaaaga
      961 ggttaccaaa gaaaaagtaa tggctgcaat tagtgagctt aattatgagc ctgatgaata
     1021 tgccagaggt atgaaaacga atagcagcaa tacaatagct cttattttac ctacgatttg
     1081 gcatcccttc ttttccgagt ttgcctacta tgtagaggaa gctctcagcc aaaaaaatta
     1141 taagcttttt ttgtgtaatg cgaacggcag tgcggaaaaa gaaaaagaat atatccaaat
     1201 ggtcaagcag agtaaagtag acggaattat aggtattacc tattcagaca ttgataaata
     1261 tgtatcatca aatttaccat ttgtcagtat agaccgccat ttttcggaac aggtttctta
     1321 tgtaacggca gataattatt taggtgggca aattgccgct caagaactac ttactcgtaa
     1381 ctgtaaaaac ttgtgctatg ttgggggtgt ttcaccttac cctaacgaaa caaacaatcg
     1441 taaagctggt ttttacaata tttgtgagga aaataaaata gctgtgaagg tattggatat
     1501 gcctgaacca attagcaatt tggaggaaca attgctcgct tttttttcgg ataatcctga
     1561 aattgatagc atttttacca tcaatgattt catggctttg gatgtgataa aagcccaaaa
     1621 aaaactaggg aaggaagcac ctaaggattt tcaaattatt ggttttgatg gagtcaagct
     1681 atcgttgcaa aaagactatt tactatcaac gattgtacag ccgatagagg aaatggccaa
     1741 ggtttcagta gaaacactca tggcgatgat tttaaatgaa gaaccgccta agcgtgtggt
     1801 agtaccggtt ttctttcacg ctggagaaac gactaaagag taaaaaaccg gtttataacg
     1861 attttttttg agataggttg acagaaagtg gtttcaatga tatcttaaaa ccaattaatt
     1921 ggaaacgtta ccaattaatt ggaaaataaa acggaaacgt ttcaaaaaat aggaggaaca
     1981 tcgatgaaaa ggagaatgtt agcaattgca gcaattttag cattaacagc tggaggactt
     2041 gcaggatgtg gcagtaagga gaaaagttca ggcagcagtg attcaggaga aattaagatt
     2101 tgggttcagt tttctgatga aacgcctgaa ggaaaagctt gggcagagat tgtgaacaat
     2161 tttaatgatg aatacgaggg tgaatataaa gctgttactg agtatattcc tcgtagcgga
     2221 agcggcggtg gatatgagga taaagtaaat gctgcaatta caaccaatac ccttcctgat
     2281 gttattacgt tagatggacc gaatactgca gcttatgctc attcaggagt cattgctcca
     2341 ttagatgatt atttgaaaga tgcggacatg gatgatgtat tagacagcat tattcagcaa
     2401 ggaacctacg atggcaaaat gtatgcgttt ggtttctcag agtccagtgt gggtgtctat
     2461 tacaataagt cgttgttcaa agatgctgga attacagaag atcaattgcc gacgttagaa
     2521 gatccttgga cttggacgga atttcaagca atttgccaaa agctgactga taaatacaaa
     2581 acgcctgcaa ttgatatgca aatggcgtcg ggagacgaaa tgctgaccta cgcatataca
     2641 ccatttgtat ggtcgaatgg cggcgatgtc gttaatgctg atggaaccaa agccgaagac
     2701 tattttaacg ataaaaaatc cgttgaagcg ttggaattta ttcaagaatt ggttgaaaaa
     2761 ggttacacca caatcagtcc tattgaaaaa ggatttgaaa ctggcaaata tgccatgctg
     2821 ctgagcggtt cttggacaat ggcagattta gaggaaaact atcaagagat tgattatggt
     2881 attttgcctt accccgtttc agatgcaact ggggagttag tttcaccaac cggcagctgg
     2941 cagttagcaa tgactgagaa aacagagaaa aaggatgctt ctgcggcctt tattaagttt
     3001 gcaaccagta cagaatctag tcgtattatt agtttaggga acagtgttct acctatcaga
     3061 aattcaacag ttgatttaat taaagatgaa gtgtcggaag gaatgcaggt attaattaag
     3121 caaaaccaaa tttctggaca tgcccgccca gtggttgtag cttatccgca agtatctaga
     3181 gcattccaac aagcagttca agatattagc tacttcgagg aaaacccaga tgtacaaaaa
     3241 gtagcagata gtcgcgctgc tgaaatgcaa caggcaattg atacttcact aaaatagaag
     3301 tttctaaagg gggccaatca agtgttaaaa aaaccgacaa tgaaagacaa tttgataggt
     3361 tacggctttc tagcgccagc tttgctgctg ctgacgattt ttctgatcat acccgtaatc
     3421 atggtaattt attatgcctt tactgattat tatttgttaa cgccagatgc tagacaattt
     3481 atcggcttag aaaattttaa gcgactgttc gctgatccaa tttttgtaaa aagtatttgg
     3541 aacacggcta aatttgttgt ttggattatt ccggtccaat taggggcagc tttaggaatg
     3601 gcacttatta tcaacaaaaa tcgtaaagga aatatctttt ttaaagtagc cttttttgcg
     3661 ccagtcgtga tgtccttagt cgttatttcg attttatggt tgtacttgtt aaatcctaat
     3721 gaaggtctgg ttaatacgct atttgcaaag attggaattg cttcgcagcc ttttttgact
     3781 agtcccaaac aagcaatgta tacgcttgtt ttcgtatcgg catggcaagg tgcaggatat
     3841 cagatgctgc tgtttttagg gggaatgcaa aatattccgc aagacgttta tgaggcagcc
     3901 gaaattgatg gtttttctaa gtttcagcaa tttcgctata tcaccatgcc attattaaag
     3961 cccacggcga tttttatttt acttaccaca ttgatttcgg cctttaaact aatcattcag
     4021 ccaatggtaa tgactcaagg tggaccaatg aattctacta tgacaatggt ttattacatt
     4081 taccaaactg gatttacaga ccgtatggta ggctactcca gctccattgc gttaatcttt
     4141 accaccatga ttggtttaat tacaattgct caaagaaaat tggtaaagga ggatgatcca
     4201 gcatgaccaa gaaatttgga ccgctaatga tcgtagaata ttgtttgctg ttccttttag
     4261 cggcattatt cattttccca atgctgtgga tggtagtttc ctctatgaag cctgaagcag
     4321 atgtctatca aaatttagct tccttcaaag cttttttacc tagtttgaat ccagctaatt
     4381 ggtttaaaac ttatcaagaa gttatttccc ggttcagtgt gggaacttat ttattaaaca
     4441 gtatttttta tggtttaacc tttgcctgtg ggtcaatcat tgtaaactct ttggcgggtt
     4501 ttgcctttgc gaaggttaat ttttcaggca agaaaattat ctttggagct ttgttagctc
     4561 tgctgattgt cccgatggag acggttttaa ttccgcaatt taccatcgtt aattcactag
     4621 gcttagtgaa tactcgcttg gcagtgattt taccagcgat ggccagcgcg tttaatatct
     4681 atttgtttag aaatttcttt atcgcgattc cagaagaaat cattgaatca gcgaaattag
     4741 atggtgcaaa tattgttaaa attttctttc acatcatgct gccaatgtct aaaccagcca
     4801 tagccacagt aggtgtctta tcctttatct ccagctggaa tgattatatt tggccgttaa
     4861 tggtcttaac tgacagcagc aaattttcaa tgcaagtggc aattactacg atcaatacta
     4921 cacagccagt ttatatcaat caagtgatgg ctgttttaac cattgcaacg attccactga
     4981 ttattgttta tatcgttgca caaaaatata ttctgcaggg acttggcggt tctggaacgg
     5041 gtataaaata ggagtgaata gtgaatgttg caaaaacttt taaaggccaa tgagtttatt
     5101 gagaaaaatg ctcaaacagt caatcaagaa taccggaata aatttcattt gatggctccg
     5161 attggctgga tcaatgatcc aaatggtttt gtttattatc aagaggagta tcacttgttt
     5221 tatcaatatt atccttacga tagcatctgg ggaccaatgc attggggcca tgctaaaagc
     5281 aaggatctaa ttcactggga gcatttgcca gtagcactgg caccaggtga aagctatgac
     5341 aaggaaggct gtttttccgg cagtgccata gaaaaggatg gcaagctgta tttgatttat
     5401 acaggacaca atgttgtgga agggcaagtt cgacaagttc agtgtttggc agtttcagaa
     5461 gatggcattc actttgaaaa atatgccgga aatccaatca tcgcagaaga tcacttagct
     5521 tctgttgcaa cgaccgaaga tttccgcgat cccaaagtgt ttcagcgaaa agaagactat
     5581 tttactgtag tcgctactaa aactgcagat gctcgtggac aaattgtgat gttccattcc
     5641 aaagatttac taacttggga gttttattcc gtattgctgg agggaactcc agaacaaggc
     5701 attgtatggg aatgcccaga cttgtttgaa ctagatggca aagaagtctt gattctttct
     5761 cctattcaaa tgactccaca aggcaatgct taccaaaata cgaactcaac tgttgctttc
     5821 attggtactg tcgattggca aacaggcaaa tttctagtag agaattttca tgaaatcgat
     5881 ggcggtttag atttttatgc cccccagacc tgtgaaaacg aagcaggcca aagaataatg
     5941 actgcttgga tgcaaatgtg gcagcgtaaa atacctacga atgatctggg ccatggttgg
     6001 tcaggttcca tgaccttgcc tagagagctg agggtggctg ataatcaatt gttgcaacgg
     6061 ccagtttcat caatttatca agtaattgat ccgcaggaaa ggattgaatg ggcgaagact
     6121 gaagagaatc gattcttact gaagggctta gtatatgacc agcactattt acgcttggaa
     6181 atcaatttaa aacaggcaac gaaactagaa cttcactatg cgaagggacc ccaccataca
     6241 ttactgctta actatgatgt tgaacgggag tgctttactg cttccaggga acacatgccg
     6301 tatgatttat caggagctga aaaggaagtg ttgaaaaagc gcagtgtgac gattcctttg
     6361 gaaaataatt gtctaaccat cgaaattttc cgtgatactt cagctattga gctttttcta
     6421 aatgatcgtc tgactatgag tacaactttt tatgagacag aaaaaggaca ggattttctt
     6481 ttgctggcag acagtgaagt aaccttttca ttggaaagcg gcttaattaa tctatagaag
     6541 ggagagctca gtgatgattt atggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc
     6601 cattggcgat gaagaaatga cgatcaagga aagagtgagc tttccgacaa cgacacctga
     6661 ggaaacaatg cctttagtca ttgacttctt caaacaatac caagcagatt tagcagggat
     6721 tgggattggc tcatttgggc ctatcgatat ccatcgcgat tccgccactt atgggtacat
     6781 tacctcgacc ccgaaattgg catggcaaaa ttttgatttc atcggtacca tgaaaaaaga
     6841 atttccgatc ccgatttctt ggacaacaga tgtcaatgcg gctgcctatg gtgagtatgt
     6901 cttcggcagt ggcaaaggat tgagcagtgt cgtttactat acgatcggta cgggtgttgg
     6961 cggcggtgcc ttacaagaag ggcgctttat cgaagggttt agtcatccag aaatggggca
     7021 tatgctcgtc gtccctcatc caaaagatga ctttgctggc agctgtccat ttcatggcaa
     7081 ctgtttagaa gggatggccg ctggacccgc catcgaaaaa cgcttaggga aaaaaggaca
     7141 agaggttgca gaagatgatc cttattggga aatcgaagcc tcctatattg ctcaatgtgc
     7201 ctacaataca accttgatgt tttctccaga tgtgatcatt tttggcggtg gtgtgatgaa
     7261 acaacgccat atgctgcaaa acgtccacga cgcatttgca aaattggtca atgggtatgt
     7321 cgaaacacct gagttaagca aatatatcgt gaccccagca ttagaagaca acgctggaac
     7381 gctcggttgt ttggcattgg ctcgagaagc ggtcttacat tcataaacga aaaaaggctc
     7441 ttcgacattt agtgttggta gagaaagata caactgaaaa tttagtcata accagttagg
     7501 cagagtgctt aactggtttt tgttttactt ggaagatcaa gccttgaatg agataaattc
     7561 ttgctcgaaa gttatggaaa tttcgatagc cgtaggctac ttgtattgtg caatagtttt
     7621 ttacaaaaaa aaggggtgcg gatatttttt tggacctttt taacaaatat atctttgctt
     7681 cttccgatat tgaagagggc ttagccctcc taaagataac ttaattcgtt gattattata
     7741 ccaatgaata taattatcca atttgtttat aaactgattg attgttgtat tcttccagtc
     7801 acgttgataa aacatctcgt tttttaatcg tccaaagaaa ccttcgcacg ctgaattatc
     7861 tggtgaataa ccctttttag acatagagtg aagcaagttg tctttgttcc aatagtccaa
     7921 ctaacaatag caccatcgta acaatcgaca agtggtgata agtagatttt ccctgcggga
     7981 attctaaatt cagtaatatc tgttaaccat ttttcatttg gcttctttgc tttaaaattc
     8041 cgatttaata aattggggtg tgcaggagaa atttccccag catacgaaga atactttttt
     8101 cgtctagaaa atttaacaaa tagattttcc tcagtcatca atctacgtac aactttttca
     8161 gaaagctttt tacccatatt ttttaaagct tggtcaattc tacggtaacc atacgcacag
     8221 aagttatgat tgaaaatcgt gataattaat tgacgttctt tgtaatactt atctggtttc
     8281 tcaagtgctt gtttttgata aaaatagctg cttttaggca actggagctg ttgaagaagc
     8341 tctttcaagg tgaactgatt tcgtaaggca tcaatcaata tcgttttttc ttgatttgat
     8401 agacaaagaa gattgacgcc tttttctttt tttagcagtt cagccgctcc ttcgagtaat
     8461 gctttttcga gctgtaattg gtgtacttgt ttttgtaagt cttctacttc ctttaaaagt
     8521 agctcttttt gtttttcctg attttttaaa gtcatacgca atggaaaatc ctttccaaga
     8581 accgtgtttt tccattgata tagagtaact ctactaattc cttcagattc ggctaaattt
     8641 ttcctattat ataaattgag ttaaattgta ttcgtttttc ctcctatagg cgtatactaa
     8701 agaaaacact tgaggagtgg ggaacatgga
//
LOCUS       DAIGTA010000082         8519 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.085, whole genome shotgun sequence.
ACCESSION   DAIGTA010000082 DAIGTA010000000
VERSION     DAIGTA010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.085"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            168..362
                     /locus_tag="NOB43_002456"
     CDS             168..362
                     /locus_tag="NOB43_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983285.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="NOB43_002457"
     CDS             631..930
                     /locus_tag="NOB43_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983286.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="NOB43_002458"
     CDS             complement(1027..1461)
                     /locus_tag="NOB43_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0983287.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="NOB43_002459"
     CDS             complement(1693..2403)
                     /locus_tag="NOB43_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI0983288.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="NOB43_002460"
     CDS             complement(2393..3253)
                     /locus_tag="NOB43_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCI0983289.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="NOB43_002461"
     CDS             complement(3258..3896)
                     /locus_tag="NOB43_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCI0983290.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="NOB43_002462"
     CDS             complement(3911..4210)
                     /locus_tag="NOB43_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0983291.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="NOB43_002463"
     CDS             complement(4253..5737)
                     /locus_tag="NOB43_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI0983292.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="NOB43_002464"
     CDS             complement(5757..6218)
                     /locus_tag="NOB43_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0983293.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="NOB43_002465"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="NOB43_002465"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCI0983294.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="NOB43_002466"
     CDS             7521..8291
                     /locus_tag="NOB43_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0983295.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
BASE COUNT         2668 a         1754 c         1359 g         2738 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tcctttttt
//
LOCUS       DAIGTA010000083         8297 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.086, whole genome shotgun sequence.
ACCESSION   DAIGTA010000083 DAIGTA010000000
VERSION     DAIGTA010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.086"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(52..1518)
                     /locus_tag="NOB43_002467"
     CDS             complement(52..1518)
                     /locus_tag="NOB43_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HCI0983296.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1905..2501
                     /locus_tag="NOB43_002468"
     CDS             1905..2501
                     /locus_tag="NOB43_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0983297.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2559..3041)
                     /locus_tag="NOB43_002469"
     CDS             complement(2559..3041)
                     /locus_tag="NOB43_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983298.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3147..3344)
                     /locus_tag="NOB43_002470"
     CDS             complement(3147..3344)
                     /locus_tag="NOB43_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983299.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3639..4397
                     /locus_tag="NOB43_002471"
     CDS             3639..4397
                     /locus_tag="NOB43_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCI0983300.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4457..4885
                     /locus_tag="NOB43_002472"
     CDS             4457..4885
                     /locus_tag="NOB43_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983301.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4931..5003
                     /locus_tag="NOB43_002473"
     tRNA            4931..5003
                     /locus_tag="NOB43_002473"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4964..4966,aa:Gln,seq:ctg)
     gene            complement(5153..5524)
                     /locus_tag="NOB43_002474"
     CDS             complement(5153..5524)
                     /locus_tag="NOB43_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0983302.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5739..5924
                     /locus_tag="NOB43_002475"
     CDS             5739..5924
                     /locus_tag="NOB43_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983303.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6007..6195)
                     /locus_tag="NOB43_002476"
     CDS             complement(6007..6195)
                     /locus_tag="NOB43_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983304.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6219..6482)
                     /locus_tag="NOB43_002477"
     CDS             complement(6219..6482)
                     /locus_tag="NOB43_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983305.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6640..6897
                     /locus_tag="NOB43_002478"
     CDS             6640..6897
                     /locus_tag="NOB43_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HCI0983306.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6968..7159)
                     /locus_tag="NOB43_002479"
     CDS             complement(6968..7159)
                     /locus_tag="NOB43_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983307.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7300..7620)
                     /locus_tag="NOB43_002480"
     CDS             complement(7300..7620)
                     /locus_tag="NOB43_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983308.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7643..8077)
                     /locus_tag="NOB43_002481"
     CDS             complement(7643..8077)
                     /locus_tag="NOB43_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0983309.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
BASE COUNT         2634 a         1636 c         1314 g         2713 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctatacccc aattctttaa attttcagaa aatattatac
     1561 atctttaccg aaaaatttaa ctaaaaaact tatttaagaa atataaacta attttctata
     1621 aaagcaagta atttttaatg gcaatatcat aaaaaaaaga agatagagat ttaataatta
     1681 tatatcagct gtttttttca aataagcaaa aattcctaaa acacaacaat gaaagcgata
     1741 actaagaaaa tccttacata acgatttttc ttattaaaat tgttttttga acttcgctta
     1801 ttttttgtga gcatatctgt ttacttactt tttgtaaggt gctatacttc atttcgtaat
     1861 caattaaaaa aatgcaaaac gcaaatcaaa ggagaaattt tattatgaca acttttactg
     1921 acactttgaa aaaccgccgt tcaatctatc atctaggacg taatgtttca ctttctaatg
     1981 aagaattaac aactttgatc aaagaagcaa ttaaagaaag cccaactgct ttcaatgctc
     2041 aatcaacacg cgcagttatc cttttcggag atgcacatga aaaactttgg gaaatcactg
     2101 aagaagcact tcgcccattg actccagcag aagctttccc aaatacacaa aacaaattag
     2161 ctggtttcaa aaatggttat ggtacagtat tattcttcaa agatactgac gtggtaaaag
     2221 gtctacaaga acaatttgaa ttatatgcag acaacttccc agattggtca gaacaatcaa
     2281 acggaatcgc aacagctaat acttgggtag cattagttga taaaggattg ggcgcaaact
     2341 tgcaacatta caacccagtt attgacgaag cagttgcaaa agaatggaat atcccttcaa
     2401 actggaaact acgttcgcaa ttagtattcg gttcaccaga aacaccggct ggggaaaaag
     2461 aatacatgaa cgatgccgat cgcttccgcg tatttggata attttatttg aaataaaaaa
     2521 cagaggttgt gacaaacatc ttgtcgcaac ctctgttttt attctggatc aatcataata
     2581 tcaatctctg cctcatcgtt taagcgttgg gacaaaaatg gaactaattc ttctaatgat
     2641 gcagaaaatt tcagcatcgg tcctcgccat ccgtttcgga aaaaattcat ttttacgatt
     2701 ttagaacctt ttggctgata taatacaatt ttattgatct cagaaaaagg aacacctttt
     2761 ttgtcaaagc tattcaaaac aagtccttct tctgtgattc ctctactgtc caacaaaaaa
     2821 ctaataaaaa tcattgctga caagatccct tttgccaatt catctgctgt aggatgactg
     2881 atgagtgtat accaaatgac tagtgacact aagaagggta tcaccaagta gacccatcga
     2941 tttcgcacag tccgataaat aatttctttt cgaaccagcc aaagaaataa aaacatcaca
     3001 acaacgaata aaaacaatag aaccgtaaag aatgttacca tgacaactcg cctcgctttt
     3061 tcttctccag aaaataggaa aagaatactg atttaccttc tcaaagaaat tggacttgca
     3121 gcacgccgca cgtccaattg ttttctttat tcaaatgtat catattttgc aacaaccatg
     3181 cttgcttttt catctaataa ttcttggtcc tctgcagcac attgggcaac tttgaccacg
     3241 gcgcagtttg tcatttttga tacaacttca ccaatgaccg tttttgtaaa accaattggt
     3301 ttgcatgcat attgttctcc taaattaatc atttcttccg tcatcaaaat cctcctaaac
     3361 tgctggaact tttctccaca ttaccactgc tatttctttg gagatttaac tcattgattt
     3421 ttatttacag ttaaaaatca accttacagg cattatagcg tactgttttc gttttcacaa
     3481 ttaaaacagc tgttgtattt agaagaattt ttttcaaaaa attaaaacat attccttaaa
     3541 aactaattat ttcctacata ttaaaatata atacttccat ttccaataaa aatacattta
     3601 taataggaaa gataaacagc tgaaaaggga gatttcaaat gaagaaaaaa acgttcaaaa
     3661 aactattgtt tctagggggc acagctgctc ttttattaag cggtacaagt tattacctac
     3721 atatccattc tccagaacat acaatgaaca ctgcacaaaa aagttcaaca caaaaaacga
     3781 aaaagacaaa agagaaagca gaagttttac tagatgttcc attagagagc cagtttgatt
     3841 ctccttcttt agaaaatggc tgtgaagtca cttcgctttc tatgctttta tctttttatg
     3901 gttatgaaac aactaaaaac cagttagctg agcaattgga ttacgtccct gttttcaatg
     3961 cagatgggac tcatggcgat cctaatgaag gatttgttgg tgatatcagt ggcggagact
     4021 gggctatggt cgtctatgtt cccccagttg cctcccttgc tcagcaaatc gtccaaacgg
     4081 attatcacac ttttccaaaa accgatgctc aactcgatga tatcaaaaaa gcactatcta
     4141 aaggaaatcc tgtctggact tctgtgacta tcaattttga agtcccagat gaaactgatt
     4201 ttatgacttg gaccacaaat aatggagaag taagagtcac tcctcttgtt catgcttgtg
     4261 tagtcactgg atatgacaaa gaaaatattt atgtcaacga tccctatggt gtaaaaaatc
     4321 gagcagtacc gatcaacgat ttttcggcga ttttcactgc aatgggtgga cagatgctaa
     4381 ctttggagaa aagctagtaa ttcaaacaaa aatcccttat actcaagata ccaaaccttt
     4441 gaagggagcg tagataatgg aaaaattcac acataaaaaa atggatccaa atgaaattcc
     4501 gattattttt gtccgtgact gcaagggaaa tgttcaaggt aaagtctcta ttaatgagtg
     4561 gaacgagcgt cgcagacctg ctaccctcaa tgaactggaa atcaaattgt atcgtcaatc
     4621 tcttgtttat tacgcagatc aagagtacga gaaagccacc gatttattga aatttctaat
     4681 tgctcgaaca gagtatactc gctttgaata tattgaacgt ttagcaaaca tctatcatat
     4741 tatgaatgaa cctgtcaaag aatatcagtt attggacacc gtcttgtcag tagcagaact
     4801 gattgccctt cctgctggat tagaaaagaa actagtacgc cgccttttac gagtaaagca
     4861 acaactatcc gatcaagaaa aataacttgc gtttttttag gaaagtgcta tgattatttt
     4921 gttgaataaa tgggatgtag ccaaactggt aaggcacttg actctgaatc aagcaattgt
     4981 aggttcgaac cctgccatcc caatttgatg tgcttgctga aaaaatgaac cccctgtaaa
     5041 agaacaatct ttttgcaggg ggattattgt attattttta ctacttgtat ttagtttaca
     5101 taattaaatt atgaataata aaatcgggcg tattcttaat acaaaaactg atttacccaa
     5161 taattgctaa tgctttctcc ggaacttttt ctctaggaac ttcctcatac gtttctatgt
     5221 gtgctccttt attgctaatt ttcaaataat gattttcttt taacacagaa agaccattaa
     5281 attcaaccgt tcgttctttc ccattggcat cagcagcttt ctgcacatac cttgctgtac
     5341 catattcatt tacttcctct ggtttttgtg tctttacata gacctctcct ttttcaacta
     5401 atggatttag ctgatcaagt ataccaggga tttctccata acttccttca gtataatatt
     5461 tcagtccaaa tagcaaaata ccactaatcg ccgccagtcc aatcaaatat ttaatcactt
     5521 tcatctttct acctccttgt tatatattca gtatatgggt cagttaaaga aattccatcc
     5581 gtcccaagtt ggagattttt ctcctacttt agaagcgaga atcgagtgtt tttttagtaa
     5641 aaatgatcgt tatttgatat tattgacgtg tggataaatc agtttttctc gttttgtcca
     5701 tgtaaaaaat catgttgata gcaaaggatg tgttcaaaat gaatcaagaa gaattatttc
     5761 aaaaagtcaa ggaaatgatt aagaacggca atttcgatgg cgcaaaacga tttatcgaag
     5821 aacataaaga acaattagga ccttataaag agaaagccca aaatctttta aaagatgtaa
     5881 atatcgacag tgtcaaaaac aaatttaaaa atctattcaa ataagtaaaa ctttcacttt
     5941 tgtaaaatca aaggaggaca atgctgctgc atcgtcctcc tttggttctt ttctgaatac
     6001 ttcatactaa aataaacgtg tcggatcgta atgataagtc acattgccgt tcagtgaggc
     6061 ttttcccacc acatatttac gattctccaa cttcagccac gcttctcgaa aagccattaa
     6121 ttcttctctt tttacatcaa tcttttcgat ttttccatcg atcaaatctt gaataagttg
     6181 ttcatatgga ttcatttttt tcctccatct gctgtcaatc aataagttgt aaaaataggt
     6241 tcatatgctt ttttggtatc tagatcttct ctgactttga ctgtcgtata aataattttt
     6301 tctactggga tactataata acttccttca ccattattga atcggtgaac gtctttcttt
     6361 gctaaaatac catttatttt attcgtcagt acacgttgtt cgacactgtt acttacaaca
     6421 tagtaaatca cccgaatatt attgatcaaa tgcaaatcga tttctaacac tacatgatcc
     6481 atgaaaatcc cactccttct ttcactttga ttatagcaag tttctcctct aatttcaaaa
     6541 tcgatacaga ttttaccgga taaatccaca aaactgcttg cgccatttcg cacaaagtgt
     6601 tattttgtat catggacttt atttatcgga ggcaatagta tgatcgcgat cggtcaattt
     6661 gttttttata ttcctttttt tattatgata agcattcttt tctattacat aaaatggaca
     6721 aaaaagaagt tttcagtttt actggcctct ttacctgctg tatattttac ttatcaaatt
     6781 ttttctttta ggcattggga aacaacgtct gtattaataa cacacatcat cgaattgacg
     6841 ctttcagtaa tttttcttat tatttggatc tattttttat ataagaatca gaattgaatc
     6901 cctcgcatgt ttaaaaagaa aacgattaaa gatgcagcaa atttctgccg atctttaatc
     6961 gttttttcta ttctgttata ccaaaaaaat gtttgaatcg gtgaaggatc gttccttgtt
     7021 ttaattctat aaattcttgt gcgatcgggt acttttcttc caaattttct ttgttctttt
     7081 cgatcaggct tttcgcttct tcatattttt tatctgcaca tagtgctttt acttcctgta
     7141 atacttttcc tgcttccatt tgcctcaccc tcttgccatt ttattgcttt aagttttatt
     7201 taagttatac gcattattct agtttcatcc caaataacct tttttcattt ttactcctcg
     7261 aactaatcag ttttctaaag gctgattggt tcgtcttttt tatttttcct ccatttcatt
     7321 ctgctcttct gttaatttat ctaatgcttt gattgatgct gcggctcttg cataatcata
     7381 gctgtataat tccataaatt tatcaggcag aacaaaccac gctggatgat aaccgttagc
     7441 tgtgacaggg aatcctttat cttgttggtt atctccatcc catctcagag caacaccttt
     7501 ttttcctttc cactttacta aagcgatcga gtatcccttc tttgtttgtg tgccgtcttc
     7561 aataattgct aaaatttcta ttttttcttt tggcgcacgg acttcttgag gacgaaccat
     7621 tttctattcc tcccttatct cattacttca cgaccaacac actgcaaggg gcatgtgata
     7681 cgacataaga agcggtcgat ccaactaatg cttgttgtat agcacctttt cctgtcgctc
     7741 ccataacgat caaatcaata ttttcttgtc cagggatgac attggcaatc aaatttcttg
     7801 gatctccagt ttcaactatt gcgtggatct cagcaatgcc gtactctttg gcatcattga
     7861 tttttttcag catggctact tctgttcttt gtttttcatc tgcatagatt tttgaaaagg
     7921 cataggcact atgggtcagc tcaactttgt tgatgattga cacgataaat aagtgggctt
     7981 cattgtcctt tgctaagtca agggcttcag cgaacgcttt gatcgattgt cttgatccgt
     8041 caactgctac catgatgttc tggtatcttt tactcattgg aaccgcctcc tttttctttt
     8101 attgtaacat ctcaagcaaa aatacaaaaa atatacgcaa tatgtaaata aaatgatgaa
     8161 caaaagcaat ttctttcaag ttatttatac atttcttttc tcatcagaac acctgttcta
     8221 atcccattat ttctgcatta tgtgaaattc ctcatcattt ttcacatcga gcgaacatca
     8281 ttctgttaca aaaaacg
//
LOCUS       DAIGTA010000084         8231 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.087, whole genome shotgun sequence.
ACCESSION   DAIGTA010000084 DAIGTA010000000
VERSION     DAIGTA010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.087"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            331..1254
                     /gene="truB"
                     /locus_tag="NOB43_002482"
     CDS             331..1254
                     /gene="truB"
                     /locus_tag="NOB43_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCI0983310.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1258..2199
                     /gene="ribF"
                     /locus_tag="NOB43_002483"
     CDS             1258..2199
                     /gene="ribF"
                     /locus_tag="NOB43_002483"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HCI0983311.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2594..3379
                     /locus_tag="NOB43_002484"
     CDS             2594..3379
                     /locus_tag="NOB43_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0983312.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3392..4243
                     /locus_tag="NOB43_002485"
     CDS             3392..4243
                     /locus_tag="NOB43_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCI0983313.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4367..4819)
                     /locus_tag="NOB43_002486"
     CDS             complement(4367..4819)
                     /locus_tag="NOB43_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983314.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5284..5652)
                     /locus_tag="NOB43_002487"
     CDS             complement(5284..5652)
                     /locus_tag="NOB43_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HCI0983315.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5802..6284
                     /locus_tag="NOB43_002488"
     CDS             5802..6284
                     /locus_tag="NOB43_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HCI0983316.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6321..7331
                     /locus_tag="NOB43_002489"
     CDS             6321..7331
                     /locus_tag="NOB43_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HCI0983317.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7446..8159)
                     /locus_tag="NOB43_002490"
     CDS             complement(7446..8159)
                     /locus_tag="NOB43_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983318.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1669 g         2441 t
ORIGIN      
        1 tgattaagaa actgaaaaaa taaataaaaa aaaacggaaa aaagactgga agaatggaca
       61 gtcttttttt tcgtttttgg gaagtgaaaa ccaaactatt tacctgtaag ccacccataa
      121 atccaatcaa atggtgcaaa gaaaaaatct tccattctat tccctccttt aaaaaaaaca
      181 taacatgatt tctatttacg tgagcatgaa ttttgttacg tttttattgc cgaaaaataa
      241 aaaccgttca ttatgatgtc aaattcgtca gtaattgatg caatgtgtta taataattca
      301 gttaaatcaa aaatgaaatg gagaaaagac atggacgggt tattaacttt atggaaagaa
      361 cgcggaatga caagtcatga ttgcgtattc aaattaagaa aaatcttaca tacgaaaaaa
      421 atcggacatg ggggtacgct tgacccagac gtagacggtg tgttgcccat ttgtattgga
      481 aaagccacaa aagttatcga atatttgaca gattctggga aaatctatgt aggcgagata
      541 actctaggtt tcagtacaac gacggaagat cgatccggag aacgggtaga aacaaaacca
      601 gtagatatgt ctttatctga agaaaaaata gatgaagtga tggcttcatt tattggtgag
      661 atcacccaga taccaccaat gtactcagcg gtaaaagtca acggtaagcg gttatatgaa
      721 tatgcccgca ataatgaaac agtggagcgt cctgttagaa aggctcagat ttaccgtttt
      781 atccggacaa gtgaattgac aagagacgaa gtgacaggaa ccatttcttg gcgcttcgaa
      841 gtagaatgcg ggaaaggaac ctatgtccgc acattagctg tagatacagg caagaaactt
      901 ggttaccctg cgcacatgtc tgatctgacc cgaacagcaa gtgccggtat gtcccagaaa
      961 gatgctctga cattagaaga agtagctcaa gctgtgaaaa atgggacaat cgatgattgt
     1021 ttgctgccaa tagaaaaagg agtgaaacga ttcaaacgag tagatattac tgatgaagta
     1081 tggcagaaag taaaaaacgg tatgagactt aattatactg tatttgcgct cccagaaatg
     1141 ccgtcagaag aaattgcttt gttttataaa ggcaaagttg tcagtatcta tcagccaaac
     1201 ccgaaagaaa aaaacaaatt aaaacctagt aaagtattga gaaatgagga ataacgaatg
     1261 aatatcatca agatcagaca tccttaccaa tcagaacaaa ttccagaaga cgatgtcgtt
     1321 ttagtactag gattttttga cggcgtgcat attggacacc agaaagtcat aaagacaggt
     1381 atggaaattg cacaaaaaga aggattgaaa ttagcattga tgactttcaa tcagcatcca
     1441 tcgattgtct ttaaaaagat cgatcctagc agcgtgaaat atttgactag ccttaagcaa
     1501 aaagaagaaa aaatggccgc tttgggtata gattatttat atgaagttga ttttacttct
     1561 tcttttgctc atttagcacc gcaggaattt gttgatcaat acatcgtagg gttacatgca
     1621 aaatatgctg tttccggttt tgattatacg tatggaccaa aagacattgc agatgtcgct
     1681 cattttcctg aatatgccaa aggaagattc aaaatcgtca cagtttctaa agaagaagaa
     1741 caaggtgaaa aaatcagctc tacccgtatt cgaggattac tagacagcgg acaagtaaaa
     1801 gaagcagcaa aactattagg ttgcacatat gaggtagaag gggtagttgt ccatggcgat
     1861 gcacgaggca gactactagg attccctaca gcaaatgtca aagtaaagag cacagttcat
     1921 ttgcctaaag aaggtgttta tgtatcggaa ataaaaattg gggaaatttg gtatccagcc
     1981 atgggttcaa ttggacataa tgatacattc ggtgaaggac gggagctgac tgtagaattg
     2041 tatattttgg actttaatca agatatctat ggtgaacatg tcgcagtacg ctggaatcaa
     2101 tttttaagag atcaagtgaa attttctagt gtagaggaat tgattgaaca actcaaagag
     2161 gatgaacaag caacagctga atatttttct cagcaataaa acattatgca taaaatctct
     2221 tgtttatgta taactagcaa tttcaataaa atgggtgata aataagccca ggaaaggggc
     2281 tgtgacaaaa gtcttgtcac agcctttttt tccaaataaa tggtttttca gaagtagctt
     2341 cttcggaaat aagccgaaat ttcacaaaaa tttgagaagt aatttttgta aattacttct
     2401 tatttcttga agctggccac ttctgtcaca acctctttct ttatagaaat aaaaggacac
     2461 tagcaattca tgaaaacgat tgctaaagcg tatcatttgc tttagactat atatcttggt
     2521 gtacactcac tttaagacgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa
     2581 aggagtgggt actatgtata aggaattaga aaacaaagtc gcagtagtaa ctggtggctc
     2641 aaaggggatt ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt
     2701 caactataac tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg
     2761 cggaaaagca gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact
     2821 tgatacggct ttagaaaatt ttgggacact ggacgtttgg attaataatg ctgggatgga
     2881 aaatcagcat ccaacccatg aacttagcct tgaagattgg gaaagagtat taaaagtcaa
     2941 tttgactggc gtttttatcg gaacgaaagc ggctttaaat tactttacag agaatgataa
     3001 aaaaggaaat atcatcaata tgtcttctgt tcatgaacaa atcccatggc caacgtttgc
     3061 tcattacgct gcttcaaaag gcggagtaaa actattcacc gaaacggtag caatggagta
     3121 cgcaccaaag ggaatcagaa tcaatagtat aggacctggt gctatccgta cacctattaa
     3181 tgcggcaaaa tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg
     3241 acgcgtaggt gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc
     3301 cagttatgtt acaggtatta cactatttgc agatggtggg atgactttat atccttcttt
     3361 ccaaggtgga aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc
     3421 agttgggtgg gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga
     3481 gatattagga actggtattg gagccgtgct cgttggctta cttgttcaat tattcgcttc
     3541 tccagctggt atttcagtga ctacattttt gattagttta ctttctggtg cattctgggt
     3601 catcggacaa acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc
     3661 aatttcgact gcattacagt tagtcggaac ctcattgatt ggtgtcttcg cttttggaga
     3721 atggtctgga agtatgggaa aaatcattgg tgcagcagca atcattcttc ttgtatttgg
     3781 ttctgcttta acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat
     3841 cagtctatta gcatcaacaa gtattggtta ttgggtttac agtgcattgc ccaaactagt
     3901 tgatgcaagc ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt
     3961 gatttatgtg attttccgaa aaccaaccgc attttctgaa gacaagagtt ggaaagcaac
     4021 aatagttgga gccatcttca gtgtgtcagc attggcttat attttttcag caaatgaaaa
     4081 tggggttgct actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg
     4141 tatgtacatc ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt
     4201 attgctgatc gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa
     4261 tctcatttat taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc
     4321 gctagaattt ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaagtg
     4381 aaatatctgt ctgcatcaat aatttttcat tgatccattg actaaaattt acgacatgat
     4441 tgaagttacc accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa
     4501 gacggtcttt tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggattt
     4561 gattgattgc tgtaaaatca cgatactgaa ggttgaaacg catcgtgatt ggtgcattta
     4621 gcatgaatcg ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa
     4681 aaagattacg ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt
     4741 catgaagata atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta
     4801 ctgagtaaaa atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga
     4861 tatttgctta atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca
     4921 agtcagaaaa ttctaacttt tctttctcta aagaaattcg ttctctccta aagtgatatt
     4981 atatttaaat atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg
     5041 tattttttcc ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt
     5101 ggaaaattca aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa
     5161 aatagcagat actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga
     5221 acaaaacctg tataagctga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa
     5281 gctttatcgc caaaatttat catgaccttt tttatcttca atattaaatg aaatcaattg
     5341 ttcaatcaat tcccagttga ttacactttt ccaaggaact ttgatgacgt tatccgtata
     5401 tacgtagcct gcttcttgga tatttttttc aagggcacga atcgctgctt tttccggtgc
     5461 gatagaaaaa tgatttttag caaaactaaa tgcaataata aaggtaccat ggtcagtaaa
     5521 cataggttgg ttccatttta cagttgtgtc tagctgggga tacgtttctg ttatcttagc
     5581 aaaaaggtct ttgatctttt gttgatgttc tttttctttg atctgattga tgatcggctg
     5641 aaatttttcc attctaaaac gcctccatta agtggtttga tttattttac cagaaaaaca
     5701 atagttatgt ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta tatttatatg
     5761 ataagatgtc tcaaataata aaatagaaaa gagacataaa aatgattgac ttggcaaaga
     5821 aattcttaca cgaaaatata tattttgagt tgtatcatca tcgagccatt tatacaaatg
     5881 aagatgcttt ggtaataaag aaagaacaag gatttacagg tacagagacc aaaagcttat
     5941 tcttaaaaga taaaaaagat aataactacg tatatctgac ttttactacg aaacaaacgg
     6001 atttcaaagc attagggaag atcgtcggta aaaggctttc tattgtttca tcagaacgca
     6061 tggaagaaca aacgggacaa aagcagggcg ctgtttctcc gtttggttat gaaaaacaga
     6121 ttccgattat tattgatgaa gagctcttat caaatgaaaa acttgttttt gcaccaggta
     6181 gaccagatca aacgatggtc atccaaacgg ttgacttaaa caaaatcatc cagctacttg
     6241 agatgccgat atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc
     6301 atacttggag gtgaagcaac atgataagtt atccattatt agaaagaaat gcaacgattg
     6361 gggttactgc accatcctca ggcgtatcag aggaacacca ttcgttactc gaatcagctt
     6421 taaagagaat ggaagaaaaa tctttccaag tagttactgg aaagacgctt tggacgcaag
     6481 ataaggaaaa atcaggtcca gcaagaaaac gagcagatga attcaatcaa atgatgcaag
     6541 atgaaaatat ccaaatgatc tttccgcctt ggggaggaga attattgatt gagattctcg
     6601 attttgtcga ttttgatgct ctacaaccaa aatggatagt aggttattca gatattagta
     6661 cgttgctact tgctgtcaca ttaaaaacag ggatagccac tgcacatgga accaacctta
     6721 ttgatttaag aggagagtac ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa
     6781 caagagaagg agaatcgatt ctacagcaac cttctgaaaa gtatcaaaaa gagtggcccc
     6841 atgagcattc atcatcttct gttttccatc tcactgaacc aacaaattgg caatcagtca
     6901 gcggagatgc agtaaggatg aagggacgat tattaggtgg ctgtattgat acgatcagtc
     6961 atttaatcgg taccccttat ggagatgtcc aatcttttaa aagaaagtat aatgatggaa
     7021 agccgatctt gtggtttcta gaaaattgtg agctatcgtc agttgattta agaagatcac
     7081 ttgttcagat gaaactggca ggatggtttg atggcagctc ggggatcatg ttcggtagaa
     7141 gtgcagcaga ggatttgtta gattataaaa tgaaggatgt atatgaagat ctgtcaaagg
     7201 aattaaaact accgatcttg tatgatattg attgtggtca tgtaccgcca caactgacat
     7261 tgatcaatgg tgcctatgca gaagtagcgg tagaagatag aaaagcgact gttttgcaaa
     7321 cgtttattta aaaaattttt tcctgccttg gagtttatca aagaccaaca aatctaaata
     7381 gaaaagaaaa tgaaagaagc tgacagtatt ttgccagctt ctttttgtat gatctattag
     7441 aaattttaat tatccataac tatcacattg atcagctgtt tcacatcatt tggattacct
     7501 gtaggaatag ctactacaga tgcattatca ataatttctt gagttgtttc tctaatgaac
     7561 gctggataag atgtttgatc tgcaggcatt tgccaatgtg aaggaactgg ataactagtg
     7621 attgtcccgt catggttact tgaatacact aaaactccct ggtaactgta tttcccagtg
     7681 agcataacca catctttcgg atagactgca ctccctgcat cataaggggc gataggtgtt
     7741 cctgcaggat aatgaataac atgtagttcg aaatcacccg atgtatctct aaaagtatta
     7801 cctctaattg ctagccaaac acgtgcgtac tcaatttgta gatcagaata tcctgctaac
     7861 ggatctattg actgagaaga ctgtgaggaa gttgtgtcta ttgttgaaga agaaatattt
     7921 gtctcaactg tactactaga tgtagaagaa gtattgggct ctgagacttt actgcttgtt
     7981 gaagatgtat tcgtttcagt agaagctgat ttctgagtac ttgatttttc agctgaactg
     8041 gtttgtttga ttgaactttt gtctgtggtc gcagatggat cactattttc tttactagga
     8101 gacgtacatc ctacaaggaa taaagagacc aacaataaaa taaaacctaa ctttttcata
     8161 tagaatacct cattattttt ttaataccag tatagcataa tcctgaattt ttgaatccgt
     8221 aaaaccttgt c
//
LOCUS       DAIGTA010000085         7792 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.090, whole genome shotgun sequence.
ACCESSION   DAIGTA010000085 DAIGTA010000000
VERSION     DAIGTA010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.090"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            636..1199
                     /locus_tag="NOB43_002491"
     CDS             636..1199
                     /locus_tag="NOB43_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0983319.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1478..1765)
                     /locus_tag="NOB43_002492"
     CDS             complement(1478..1765)
                     /locus_tag="NOB43_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0983320.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1755..2084)
                     /locus_tag="NOB43_002493"
     CDS             complement(1755..2084)
                     /locus_tag="NOB43_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0983321.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2389..2718
                     /locus_tag="NOB43_002494"
     CDS             2389..2718
                     /locus_tag="NOB43_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983322.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(3005..3490)
                     /gene="vanZ"
                     /locus_tag="NOB43_002495"
     CDS             complement(3005..3490)
                     /gene="vanZ"
                     /locus_tag="NOB43_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCI0983323.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3643..4554)
                     /gene="vanY"
                     /locus_tag="NOB43_002496"
     CDS             complement(3643..4554)
                     /gene="vanY"
                     /locus_tag="NOB43_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HCI0983324.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4982..5590)
                     /locus_tag="NOB43_002497"
     CDS             complement(4982..5590)
                     /locus_tag="NOB43_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI0983325.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5596..6627)
                     /gene="vanA"
                     /locus_tag="NOB43_002498"
     CDS             complement(5596..6627)
                     /gene="vanA"
                     /locus_tag="NOB43_002498"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI0983326.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6620..7588)
                     /locus_tag="NOB43_002499"
     CDS             complement(6620..7588)
                     /locus_tag="NOB43_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI0983327.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2377 a         1548 c         1297 g         2570 t
ORIGIN      
        1 cactctcctt gtatgcttta gcgggtatta caatttgagt gtaacataaa tggctttttt
       61 atttgtctcg cttaattata caaacggcga agttaaaact tttttagcag attttaaagt
      121 ttcgtcaaaa ctaatatatt ctggtagctg agcattcaaa tagctttcag acttcagaag
      181 aaaattacga gcatttttat agtccatctc taataaagtt attctttttt tatccaatac
      241 attcagctca attccttata atattctatt ccttagtatc tcaacattat ttactttata
      301 aaacgaataa attttgtagt tctaattcaa atattgcatg ttatatctaa tatgggagca
      361 ttttataatt ttcattgtga taaactcgtt attaacttta ggatacacta gttaggatta
      421 aattaggtat ctagaaattt acttaagatt tttttgttta tttcgtatac acactcgtat
      481 caaaaacaat cgattatgag acaaaatgaa atgacctctt ttattaaata aaagaggtca
      541 tattttgtat cataacttgt tgcattaact atgtatctat aactcccttt tatgatacaa
      601 tcaagccaga attaaagtac gaaaggaaga aaagcatgag tggatacatt tatggttatg
      661 cccgagtgag tacacgttca caagaactaa atcgtcaatt agacttactc aatgaacaaa
      721 attgtaatga aatcctaact gagaaaatga cgggaaccaa agcggttcgt ccccaactaa
      781 atcgtttaaa agataaaatt cgtccgggag atacggtaat tgtagaaagt ttttctcgat
      841 tgggtcgtag tacaaaggat ttgattgacc ttgttaccta ttttgaagaa caccatgtta
      901 agctggtgag cttgaaagaa aacttcgata ccagcacgcc tcacggacgc ttaatgatga
      961 ctgtcttcca agcatttagt cagttcgaac gtgatttaat tgttgaacgt accaaagaag
     1021 gtttgaaaag tgcacgtgcg agaggtcgta aaggtggccg tccacgagtg aaccagaaag
     1081 atgttgatcg agcagtaaaa ttgtataaaa gtcaggttta tagcgtaaaa gaaattacgg
     1141 aaatgactgg tattagcaag gcaacactct accgctactt aaaagacaat agggaataat
     1201 ctattttaat ctttaggaat ctataatatt tatgggagaa ttagagtgat ttttttatta
     1261 ttactaaaaa acaatataaa ataacgcatt ttaagccctc tttgtgcata aggatgaagc
     1321 ttttaatttg aaagaggctt aaaatgcgtt ttaatttttt ctatttttca taaatatata
     1381 ggttagtggt ttaaaattat agggtattac aactctcagc tgttaaaaat tatcttttaa
     1441 agtgtcgtct atcctctcaa gttgaaacat tgggttctta cctaatcttt tttaattgtt
     1501 cataaaaatt ttcatgcgtt ccacatagta agataggtat cactgcatta tctttaattt
     1561 catatgcaac gcgatatgtc gtacctgcat acttgaatcc aatagcccaa attcctgata
     1621 aatcacccgt tttttgttct cccgaatgag gacgaactgc tatctcatca taaattatcg
     1681 ttaaaaattg ttcttttaat gttttctctt ttaatttttt tagatacttt attacgtgtt
     1741 tagaaggtag aatctcataa gccaatttct gctgccaact cctcttttgt catcggttta
     1801 gaatttgcaa cagtatcttc agcaatagat ttaaatgcag aagttaacgc attttttcta
     1861 tttctaaatt cttttaagat ctcttgtttg ctataacctt ctgaaagaat atcagccaaa
     1921 atatcttcac taaaatcaaa aaattctttt ttaggctcta caaactcata aaggatacca
     1981 ttctctacaa gcttagcttc tacttcaaca ccattgggca catcgaattc tttagggacc
     2041 gttaacataa tagaatttcc ttgttttctt gtttttgtaa tcatattatt tcctccatta
     2101 ttttacattt cgtaattact tagtaattac attgtacgct atttttagta gaaatacaaa
     2161 ataataaaac tcctttagaa caattttcaa aggagtttta tttgattagg aaattatgta
     2221 gaataataat atgtttttaa cttggaatca aaaacgcact tgcaagtaag tttacttcaa
     2281 tacatgaaat tgcttataat agtgtattgg aattaaggta gattgacaaa agagtgatca
     2341 aataggtata cttcattcaa ataatcgttt gaatgtgagg tgagatgaat gaaaaaagtt
     2401 tgccaagtga ctgtcgtaca taaagaaaaa gtaaatggaa taaaaaataa attggatcaa
     2461 aaagattttt caaacttact tgtgttaggg aaatgtttca gcgatttttc tagaattaaa
     2521 attttctatg ctttagaaac ctataaggaa atgtgcgtct gtgatttagc agaaatactt
     2581 actgctagtg tcgctacaac gtcacaccat ttacgttttt taaaaaaaca tggaatggca
     2641 aaatcacgtc aagatggaaa agtagtttat tactctttag cgaatgaaga catcctttcc
     2701 gctattcgtg ttttttaaag ttatcagaaa atctatctat gaaatcttag tttgggggta
     2761 ccgtcaggaa aatgcggatt tacaacgtta aggaaattta ttaaagagac caattcctca
     2821 gcactaaaat tgataattgg gctttctttg ttactatagt gttaggtaag ctttttactt
     2881 tatcaccggt tttcccctca cttcacacct acgggcgagt ttccccacat cccgttttcc
     2941 atctaatcca attcattcaa tatctttatg tgtatgaaag atcagattgc ttgatttaga
     3001 catcttacac gtaatttatt cttaaatggg tacggtaaac gagcaataat acgagcaaaa
     3061 gtatacctac aaaaataata actctgtcta attttttttg attcatatgc ttattgctta
     3121 aaccatataa tttcagtcca agaaagcctc caacagtatt tgtaattaca tctgttatgt
     3181 ctgtcgctcc aatagcgaag ataaattgaa ttatttcaaa agtaagactt aaaaccagta
     3241 caaaagcaaa cttaggtaaa aatccgattt ctttaaaatt gacattcaaa agcaagccaa
     3301 atggaataaa gattataaca ttatctatca tctctctgaa attcccagta gcagtaaatg
     3361 gagtcaagtt aagacttctt tgatgataat taaatactga taaaatattg tattgtaatt
     3421 tgaataacac taaccagatt agtgtcacta aatataaagc tagcaatcct ctagataata
     3481 tttttcccaa tataatttcc tctaattctt ttgtttaagt tgtatcatta gtatagcaat
     3541 gtcctagtta acgtgggttt taaattaaaa agctaacgtt accccaaaag tgctagtaca
     3601 ataatgctgt tcattaattt cgttggtttc attccgccat ccttacctcc ttgaattagt
     3661 atgtgttgat ccgggaaaca ctgtcacaat tacaccgtct atattgtttc ctgatatctc
     3721 ataacgaaga ttagtcggca catgaatggt ggtattttta gtaacaggat aataaaagat
     3781 ctcatatttt tccccattta cactaacaga aatggttttt tcttctttta ggtaatccat
     3841 atattcctcg agaacgaaat tcttttcttt cataatcgca ctatgtggta aaccaacata
     3901 gcgaatatgc catagttcat attgaattcc tgttaactct gttttgtcct ctggataacg
     3961 taaaatgaac ccgtatttcc aagcattttc ttctatccac tttccttcag gggctcgttc
     4021 cattttcgtc aagcttgatc ctacatctag tgataaacct gaattatgct cactataacc
     4081 tgctggtaag gcatactcag cccccatttc ttggtaaagc acactttgct catcaaagtc
     4141 tcgatagcca ctattaataa taaaatgact aacgccaccc tttacagcat cattgaccat
     4201 ctctgaaaat ttttgtgcta tttcttttga catataaata ttactatcaa gcaacccgta
     4261 tccatttatt aattcgtcat gtttagataa attcacgata tctgacttca cactttcttg
     4321 gcgaacagga tatttactat tgattaatag cagatttcct tgataaacct gttcttctgt
     4381 aattgttttc tcttgggtat tttcagaagt cccactattt tctaaatgtt ctttgggatt
     4441 ttgatcataa ttttgaaatt cgactttttc ctgagaaaac agtgcttcat taacgtagtc
     4501 ataacctaag tatattaaga ataacaataa caataaaaaa aacaacttct tcattttcag
     4561 tctcctcctt aactatatag ttggaagtat gaaatatttc tagaatcttc cccttaaacg
     4621 gcacaatctc gtttgagatt gtgccgtttt gccccgtaaa ttacagtcaa ttatttcgcc
     4681 ctactggatt tactattatc accaatgtag atgaattttc ataagtgata cccatgctga
     4741 atttaacgag gctgaactgc ctgttgacaa tgggcggtgt gaaataccac ccctctatgc
     4801 gatcagtctt attatcaggc tatcttgccg cagcgcacgc agataatgac cgcaatatcg
     4861 ctctgcctta catcttcaat actatctact atatataaat tccctaagaa ccagttacat
     4921 acgtcgggtt tcctgccgaa agagttagct tatatagttt gtccgtgcaa cggttaaaag
     4981 tttatttaac ggggaaatca aaatagctat tggggtatgg ttcgtctctt aatacatagt
     5041 gccaccattc gaggctatat gcttcaaacc cactgttttc catgatggag cgcaaacgtc
     5101 tgcgattttg cgcttcattg catgatattc catttgccgc atgatgagag cgttcatcca
     5161 taaaatcaaa tcggctcccc attggtacaa gctcacccgt gtctaatcga taaagcgtaa
     5221 gatcaatggc actgccgcgg ctatggcttg attttgaagc cacgtatcct tttgaaatca
     5281 tctcagttcg gtcaatattg ggataataac tttcctttgt caggttattt tccggctgtg
     5341 cagcccattg cataaaacag tttacagcac gattaggacg gtaaccgtcc catagaagca
     5401 atccgtaccc ttgggtagca gccagttctt ttgccttcaa aagcgattca gccaactcgt
     5461 atgtccctac aatgcgattt acttcataac cgtcaaccgg ttttccggtg aaattatccc
     5521 aagtggcata tttagcgtcc caacgaacac cgtgtactat ttcatctaaa aaagtaaatc
     5581 ctatttccat gcttatcacc cctttaacgc taatacgatc aagcggtcaa tcagttcggg
     5641 aagtgcaata cctgcagcgg ccatcatacg gggataacga ctgtatgacg tgaaaccggg
     5701 cagagtattg acttcgttca gtacaatgcg gccgttatct tgtaaaaaca tatccacacg
     5761 ggctagacct ctacagccga gcgctttata tatttttttt gccgtttcct gtatccgtcc
     5821 tcgctcctct gctgaaaggt ctgcgggaac ggttataact gcgttttcag agcctttttc
     5881 cggctcgact tcctgatgaa tacgaaagat tccgtactgc agcctgattt ggtccacctc
     5941 gccaacagct aacgcggcac tgtttcccaa taccgcacaa ccgacctcac agcccgaaac
     6001 agcctgctca attaagattt tgctgtcata ttgtcttgcc gattcaattg cgtagtccaa
     6061 ttcgtccgcg ctattgactt ttttcacacc gaaggatgag cctgaacgcg ccggcttaac
     6121 aaaaacagga taggtaaacg tagctgccac cggcctatca tctttattaa taacccaaaa
     6181 ggcgggagta gctatcccag catttttcgc aacgatgtat gtcaacgatt tgtccataca
     6241 aattgctgag ctttgaatat cgcagcctac aaaagggata ccggacaatt caaacagacc
     6301 ttgtatggat ccatcttcac ctgacttgcc atgcaaagct gaaaatgcta catcaacatg
     6361 gttgatttca tattcatggt tctttttaac aagtaatccg tgcatttttt tatccggcga
     6421 gagtacagct gaatagcaat tgtcgttttc ccattccgcg caaggttttt cgcacatttt
     6481 ccatacacca gatttcgtaa ttccaatgta taacggctcg tatttttctt tattaatgtt
     6541 agcggctatc tctattgcag attttaccga tacgtcatgc tcctctgagc aacccccaaa
     6601 cagtattgca acttttattc tattcatgct cctgtctcct ttcaaaatcc aaacagtttt
     6661 taatggtttt ttcaacggta tcacgcaacg cttgctcggt ataataggcc gtatgcggtg
     6721 tgattatcac gttaggcatt ctttgaagtt taagtaaaaa ttgattatca attggttttt
     6781 gggtgcaatc agagtagaaa aactcttcct ctccttccaa tacatccaat gcggcaccgc
     6841 ccagtttccc gttttctaat gctttaacca actcataggt atctacaagt ggaccgcgcc
     6901 cagtattgat aagaaatgct ccttgcttca ttctctgtat ttgttcgtgg ctgataatat
     6961 agtgcgtatc cgtattgagc ggcacatgaa gcgtaacgat atcgctattt tgcagcaact
     7021 catcaaacgg tacatagttt acctctatac ttcggctgcg actataagcc aacactttac
     7081 atccaaatcc tcgcagccgc tcaataaccg ctttgcctat ctggcccgtt cccaccacac
     7141 caactgtcat gtcgctgagt accttgccac ggtcgctgtc caacctgaaa tcatgttttt
     7201 ccacagagcg cacaatcgat tttacgttgc gtactgccat aagaattagc atcatagtat
     7261 aatcggcaac gctatccggc gagtacgcca cattgtcgac agtgatgccc attctcttag
     7321 cagcagttgt atctatatga ttgcagccga tgcttcgggt agaaatatat ttcacaccgg
     7381 ctctcttcag cgcaagaaga atagaggcgg aaatctctga tttatgtccc acactgatac
     7441 attgattgaa aggcgcggat ttggcgttgg attccgacac gttggcgtta attatcgttg
     7501 ccataacgcc aaagcgaggc gaaagagcat ggaatgcatc tgcctcatcc tgctcacatc
     7561 cataaacagt aatgccgatg ttattcataa ttaagaccaa ccctttctgt gaaaggcacc
     7621 aaataaaacg gggatgccaa tggtaatctt gtcaaatctt tctctgaaga acgaaaacgg
     7681 ctcgttctta cggtattaag tctaccgtgt aagaacgagc cgtttcttaa tattaaattg
     7741 ttaatttcct aagaaaaagt aaagataacc ttgagatttt cctaaaaaat ta
//
LOCUS       DAIGTA010000086         7689 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.092, whole genome shotgun sequence.
ACCESSION   DAIGTA010000086 DAIGTA010000000
VERSION     DAIGTA010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.092"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            1..664
                     /locus_tag="NOB43_002500"
                     /pseudo
     CDS             1..664
                     /locus_tag="NOB43_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            788..1120
                     /locus_tag="NOB43_002501"
     CDS             788..1120
                     /locus_tag="NOB43_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983328.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
     gene            1245..1502
                     /locus_tag="NOB43_002502"
     CDS             1245..1502
                     /locus_tag="NOB43_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983329.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKAFYHTFIEKITFDPNQK"
     gene            1734..3329
                     /locus_tag="NOB43_002503"
     CDS             1734..3329
                     /locus_tag="NOB43_002503"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCI0983330.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLK
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQAIFQLNDLNKAFVQLSTTYDQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSAKWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENETWLQGALEVFKHEQ"
     gene            3319..4515
                     /locus_tag="NOB43_002504"
     CDS             3319..4515
                     /locus_tag="NOB43_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCI0983331.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGEVVQIVMGQSPNSENYTDNP
                     NDYILVQGNADMKNNRVVPRVWTTQVTKQAEKGDLILSVRAPVGDIGKTDYDVVLGRG
                     VAAIKGNDFIFQQLGKMKENGYWNRYSTGSTFESINSNDIREALITIPDVKEQQKIGA
                     FFKQLDDTIALHQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKLGEV
                     SPLRGGFAFKSNKFVKEGIPIVRISNILSNGSVGGEFVYYTAQEKDENYLLPDKSALL
                     AMSGATTGKVSILNNPNNNKVYQNQRVGYFTKTKNVDYSFISTLVRSKIFLDQLNSVL
                     VAGAQPNISSKDINVFELTIPKNIEEQKKIGNFFKQLDDTIALHQRKLDLLKETKKGF
                     LQKMFV"
     gene            4529..7678
                     /locus_tag="NOB43_002505"
     CDS             4529..7678
                     /locus_tag="NOB43_002505"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HCI0983332.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMESIKKESYLDPTVFESDEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENNRDSSVQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKKKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHA
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         2740 a         1240 c         1549 g         2160 t
ORIGIN      
        1 tttcctaatg gtgactttcc tagtaggagt cgattcactc gcttaagttc aaacttagct
       61 tacactatca agattattcg atactttttc atcaagaagc tcaccaaagg tgaactagtc
      121 ggaattatag atagttttcc tagtccatta tgtaagccag ttagaaatag acaagcaaaa
      181 ctattgaatc aaatagccaa agttggctat aactcaacaa aaaaatctta tttttatggt
      241 cttaaaattc atatgatcgt tactaagact ggctttccga ttacttactc aatcacgaat
      301 ccaggtgtcc atgacgtgaa agtgttagag actagcgaat cttcccaata tcctagggga
      361 cagaggatat attagccata aaatccatga aaagcttgcc cttaagggca ttactatatc
      421 cgttccgcca cgtaaaaaca tggataaatc ataaaaacta gaccacagct tacttggaaa
      481 acaaagaaaa acagttgaga ctgttttttc ttccttagaa aaattaggtt gtcaaaattt
      541 caactcacgt tctgttaaag ggctagagag tagatttgaa agcatattac tggcttacag
      601 tgttctatta agtcgagcac aacgacgttt tgaaggaact ttgagatatt ctttaggata
      661 ttaaaattaa ctagcaccac gggtaatgaa ttattatctt ccaataggtg ctccacagaa
      721 ttctaaaatc aaaattccta atgacattgt aaatgatggt gacactcaca atgtaataaa
      781 aggttttatg ccccttgatc tatcaactgg gagaaaaatt cgattttcag aaattcagta
      841 tgaaggaatt ggttttactc ttatagattt aaaaaattca acttttgaaa taaaagaagg
      901 attagattta aaaaatctcc tttgtgcaga tgataaaatc aaaaaaatac aattgtacaa
      961 agtccctata ttaacaccaa cagtacttac aatgttggag atggaaaata atattaatta
     1021 tattgactca ggttcagatt tgctgattag gtggcaggta ataactaatt ttcttatgga
     1081 attaaaaaaa tacagtaata ctcaaacgaa gttctcttga agttataaag aatacaataa
     1141 atataaattt cctttagact atattaaaat cagcaatcga aggaaaataa acgaagaaaa
     1201 tggtacgcaa aatctaacta ttagagcaaa aacaggaagc tgctttggaa gatagtcccg
     1261 aactatttcc gatgttaaaa gatcgtttaa atgaattgac tgaaaaacga agacagttac
     1321 aaattcgaga gaatgaaatc ttagggatct ttcaacaaca aggggaaccg attcaagtca
     1381 aagatgtcca acagatattg actagtttgg attgctttct tatccagagt gagaagaagc
     1441 aagttaaagc tttttatcac acctttattg agaaaatcac ctttgatcct aatcagaagt
     1501 agatattgcc gatcccgatg agattcacac ctactgtgat ttgataattg aatgagtaat
     1561 atcaaatagc cgtatccaaa ccaaaggata tggctatttt tgtgttaggg atatacgtca
     1621 cgcagcttgt tatcaagaat aagtttcttt atttttttgc tttttctaaa agggagtatg
     1681 ctaaaataag agggtatata gcaactttaa ttaagagata ggagtgtatc tttttgggtg
     1741 cagaattaaa tcaaaaatta tttagtgcgg cagataatct ccgtagtaaa atggatgcgt
     1801 cagaatataa aaattattta ttgggactga ttttctataa atatttatcc gatcgattgt
     1861 tgaaacaagt ggttctttta gcagatgaat ccttagagga atatgatacg gtaagcaaac
     1921 aaacgatgtt gtatcgtgaa ttactttcag atgaagaatc aaaagaagac ctgattgcca
     1981 caatcgtgga tattttaggt tatgcgatct caccagagta tcttttcaat gtgttagcag
     2041 atcaagcaaa acaagcaatt tttcaattga atgatttaaa taaagcattt gtacaacttt
     2101 caacgaccta tgaccaattc aatgggttat ttgatgatgt ggatctccaa tcgaaaaaac
     2161 ttgggacaga tgagcaacaa cgaaatgtca cgattaccga agttatcaag aaattaaacg
     2221 acgtagatgt tttaggacat gatggagacg tgatcggtga tgcgtatgaa tttttgatca
     2281 gtcaatttgc ttcagaagca gggaagaaag ccggagaatt ttacacgcct catatggttt
     2341 ctgatatgat ggcacaaatt gtgacgttgg atcaaaaaga acgacgattc tttagtgttt
     2401 ttgatccaac gatgggttca ggttcattga tgttaaacgt acgtaactac ttaactcacc
     2461 cagataacgt taaatatcat gggcaagaat taaatacaac gacatacaat ctagcaaaaa
     2521 tgaacttgat tttacatggg gtagatgccg aagaaatgaa tctccgcaat ggggatacgt
     2581 tgaataagga ctggccaaca gatgaacctt acacatttga tgcagtagtg atgaacccac
     2641 cctattcagc aaaatggtca gcagatacga ccttcttaga tgattctcga tttaatcgct
     2701 atggaaaatt agcgccaaaa tccaaagcag attttgcgtt tcttcttcat ggtttctatc
     2761 atttgaagga aacagggact atggccatcg tcttgccaca cggagtttta ttccgtggtg
     2821 ctgcagaagg agttattcgt caaaaattat tagaagacgg cagtatttac gccgtgattg
     2881 gtatgcctgc gaacttgttc tttggtacat cgattccaac gacggtgatt gtattgaaga
     2941 agaatcgtca aactcgagat gtattattca ttgatgctag tcgtgaattt gttaaaggga
     3001 aaaatcagaa taaattatcg gaagaaaaca ttcaaaaaat cctcgaaacc tacgctgaaa
     3061 gaaaagatgt cgagaaatac gctcatttgg caacctttga tgaaatcaaa gaaaatgact
     3121 ataacttaaa tattccacgc tatgtagata cgtttgaaga agaagaacca attgatatgg
     3181 ttcatgtcgg aaatgacatc aagaaaatac gacaagaaca gcaagtgcta gaaaaagaac
     3241 ttttagaagc gatctcttcc ctgcaaacaa cacctgaaaa tgaaacgtgg ttacaaggcg
     3301 cgttggaggt gttcaaacat gagcaatgat acacaaccag aaatccgttt cccaggattt
     3361 acggatgatt gggaacagcg gaagttgggg gaagttgttc agattgttat gggacaatcc
     3421 ccaaattcag aaaattatac agataatcca aacgattata ttttagttca aggaaacgca
     3481 gatatgaaaa acaatagagt tgttccaaga gtttggacta ctcaagttac aaaacaagca
     3541 gaaaaaggtg atctgatttt aagtgttcgc gctccagtgg gagacattgg aaaaactgat
     3601 tatgatgtag ttttgggtcg tggagttgca gccattaaag gaaatgattt tattttccaa
     3661 caactcggaa aaatgaaaga gaatggctat tggaatagat atagcacagg gtcaacattt
     3721 gaaagtatta attcaaatga tattagagaa gctctgatta ctattcccga cgtaaaagaa
     3781 caacaaaaaa ttggtgcctt ctttaagcag ctagatgata cgatcgctct tcatcaacgt
     3841 aagttagatt tgctgaagga aacgaaaaaa ggattcttac aaaaaatgtt ccctaaaaac
     3901 ggagcaaaag tgccagaaat tcgttttcct ggatttacgg aagattggga acagaggaag
     3961 ttgggggaag tatctccgtt gcgtggagga tttgctttca aaagtaataa atttgtaaaa
     4021 gaaggtatac ctattgtaag aatttcaaac atattatcaa atggttcagt tggtggtgaa
     4081 tttgtttatt ataccgcgca agaaaaagat gaaaattatt tattacctga caaatcagct
     4141 ttattagcta tgtctggtgc gacgacagga aaggtatcta tcttgaataa tcctaataac
     4201 aataaggttt atcaaaatca acgggttgga tattttacta agactaaaaa tgtagattat
     4261 agtttcattt ctacattggt tcgttctaaa atttttctag atcaattgaa ctcagtattg
     4321 gttgcaggtg cacaacctaa tatatcttct aaagacatca acgtatttga acttactatt
     4381 cctaaaaata tcgaagaaca aaaaaaaatc ggtaacttct ttaaacaact cgacgacacg
     4441 attgctcttc accaacgtaa gttggatttg ctgaaggaaa cgaaaaaagg cttcttacaa
     4501 aagatgtttg tttagggagg gaagataaat gaaaattagt caccgtgagg aagcggaagt
     4561 agaagaacag ttgattcgtg tacttgggga aggacataat cagtggacgt atcgtccgga
     4621 tctaaaatca gaagaagatc tttgggtcaa tttacgtcaa aaaattatct caaataatca
     4681 agcagaactg aatgattttc ctttgaccga taaagaattt gaaacgatca aaacggaatt
     4741 actgctacgg acgaaaaccc catttgatgc tgcgaaatgg ttaaaaggtg aaaatgggat
     4801 ggctcggatc acgattgaac gggaagattc gcaattgggt tctgtctcac ttatccttta
     4861 ttccaatcaa gacattggtg gaggaatctc tacgtatgaa gtggttcatc aaattgcaaa
     4921 acgtggaagt aacatagaag cgcgggatcg acgttttgac gtcaccttat tgatcaatgg
     4981 attaccgatt gttcaaatcg aattgaaaca agtaaccgca aaagatggcg tttatcaggc
     5041 ctttaatcaa atcaaaaagt atgcagaaga aggcatgttt cggaacaata tcttttcgac
     5101 cttacagttg tttgtggttt ctaatgaaca aacgacccgg tattttgcaa atgctttacc
     5161 gaaggatttg catcctaagt ttttatttag ttggcgaacg aaagacaatg aaaaagtgga
     5221 aaacttatat gaattttgta aacaagtgct aaatatcccg gatgcccatc gcttgattgc
     5281 ggattatacg attgtcagtg aagatcaaga caataaaacc ctcatggtgt tacatcctta
     5341 tcaagtgcat gcgattcaag ccttgtttat tgccgcaaat aaacatcaat cagggtatgt
     5401 gtggcatgcg actggttcag gaaagacgtt gactagtttt gtatctacta agcttttagc
     5461 acgaaaatcg gggatcgatc gaacgatcat gttagtggac cgcaaagatt tagataatca
     5521 gaccaccaca gagtttacga aatttgcttc ggaatttaat actgggattt cttccgggaa
     5581 cgccaaagcg aatagcttga tcgtgggaac aggaagtgcc aaagaattaa gtgaaaccct
     5641 gttggcagat gccaatgcaa atgttgtaat cattacaacc cgtcaaaaac tagatgcggc
     5701 gttgaaatat gcaaagaaac aggaagagaa aaaaggaacc aatcgcttcc aaaaattaat
     5761 ggggcaacat atcgtgtttg tagtagatga gtgtcatcga gcgttaagtg ctgaaaatat
     5821 ggaagaaatc aaaaaaatgt ttccgaagtc cacttggttt ggctttacag gtacaccaat
     5881 tttccctgag aatcggaaac aagccaaagg gcaattagca cgtacgaccc atgatcagta
     5941 tggagaggtc ttgcacacct ataccatcaa gaatgcatta gaagatggct cggttttagg
     6001 atttcaagta gagcatgaaa acaccgtgga gccaacttca ttagagaata aaatctatcg
     6061 gaaattaaaa gaagtagaaa catatgcaga gtattcatca gaacagatca atcgtatgat
     6121 cgatcaaatg gagtcaatca aaaaagaaag ttatttggac cctactgttt ttgaatcaga
     6181 tgaacatatc caaaaagtca ttcataaaat gttccgtcca gataatgcct atacaaaatt
     6241 tgattttcga aatggccgtc caacgaagtc tgcgatctta accacgagtt ccattgacat
     6301 ggccaaaaag tattatcgag cgatcaaaga aatgacgaaa gaacctgact ggttaacaaa
     6361 agagtttcct aatcagccca ttcgtgaagg aagaacgatg gaggatcctg attttccacg
     6421 aatcgctatt acctattcat tagaagaaaa caaccgagat tcaagtgtcc aacaagaaga
     6481 aatgcaaaaa attattgagg aatataatca gtattatgat actgcctggt cattagcaga
     6541 cattgagcgt tataacggag acatcaataa tcgtttggca cgaaaaagag cggaattcaa
     6601 acaatttggg aaacaaatcg atttagtgat tgtagtggat cgtctattga caggttttga
     6661 cgcacctacg attcaaaccc tatttgtgga tcgtaatcta gagtatgcag gattgattca
     6721 agctttttca cgtacgaacc gtacgtatcc tgaaaagaaa aaaggattga ttgtgacgtt
     6781 tcgtaagcca gcgacaatgg agaagaatgt cgaggatgcg acaaaactgt attcagaagc
     6841 aaaagaagaa tcgggtttga tttatccaag ttatcaggaa tccaaaaaaa gattcaagca
     6901 agcatatggt aagttaaagg aggtttcatc catggaatcc attgatgaac atacgccact
     6961 tgaaatccgt atcgagtacg tcaaagcatt tcaagaattg aatcgtgcgt atgaatcgtt
     7021 agtgacttat gacgattaca atgatgacat ggtgaaatct ccaactttga acaatcaaat
     7081 tcaacttttg gaagaacaaa ttggcgtgta cgagaccgta aagggttcat taatagagga
     7141 agagccagaa aaagagggag aagatttttc aacgatcgaa ttttatagtg aaaataccac
     7201 taagttgtat gatattgatt ctacttatat tgatcaatta ctaggaactt atgctgcgaa
     7261 tagttcagat gcacgagaag aaattgaaaa agctttggct aaattgaata aaacagaagg
     7321 agtcaaagaa gtttaccgac aaattttaaa tgcatttgat gtggggactt tagatagtaa
     7381 tgaagatatc tttgtcatta aacgtcgcta ttttacacaa gcaagtgatg atttgattca
     7441 tgccttttcc aatgagtggt ttgtctctga gaaagaatta catgcttcta atctgcaata
     7501 tctaccaggt gaagatccaa ttcctaatat gaaagcaatt atcaacagta aggattacga
     7561 aggatataaa gccaaacatc cagaagccaa gccatttaaa tacccacaag aaatgaagcg
     7621 agcctggcgt aaaatgttag atgatgagtt gattccactt gagaatgaat tgaggtaaac
     7681 gagaagagt
//
LOCUS       DAIGTA010000087         7600 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.093, whole genome shotgun sequence.
ACCESSION   DAIGTA010000087 DAIGTA010000000
VERSION     DAIGTA010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.093"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(943..1356)
                     /locus_tag="NOB43_002506"
     CDS             complement(943..1356)
                     /locus_tag="NOB43_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HCI0983333.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="NOB43_002507"
     CDS             complement(1812..2297)
                     /locus_tag="NOB43_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983334.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="NOB43_002508"
     CDS             complement(2436..2651)
                     /locus_tag="NOB43_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HCI0983335.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="NOB43_002509"
     CDS             2875..3675
                     /locus_tag="NOB43_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0983336.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="NOB43_002510"
     CDS             3694..5562
                     /locus_tag="NOB43_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI0983337.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPTNRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="NOB43_002511"
     CDS             5555..6046
                     /locus_tag="NOB43_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCI0983338.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="NOB43_002512"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="NOB43_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCI0983339.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="NOB43_002513"
     CDS             6606..>7600
                     /locus_tag="NOB43_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCI0983340.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1214 c         1443 g         2236 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccaccaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAIGTA010000088         7581 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.094, whole genome shotgun sequence.
ACCESSION   DAIGTA010000088 DAIGTA010000000
VERSION     DAIGTA010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.094"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..662)
                     /locus_tag="NOB43_002514"
     CDS             complement(<1..662)
                     /locus_tag="NOB43_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI0983341.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HD"
     gene            complement(1099..1668)
                     /locus_tag="NOB43_002515"
     CDS             complement(1099..1668)
                     /locus_tag="NOB43_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0983342.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1742..2065)
                     /locus_tag="NOB43_002516"
     CDS             complement(1742..2065)
                     /locus_tag="NOB43_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983343.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2219..3031)
                     /locus_tag="NOB43_002517"
     CDS             complement(2219..3031)
                     /locus_tag="NOB43_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983344.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3385..4233
                     /locus_tag="NOB43_002518"
     CDS             3385..4233
                     /locus_tag="NOB43_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HCI0983345.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4378..5319
                     /locus_tag="NOB43_002519"
     CDS             4378..5319
                     /locus_tag="NOB43_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HCI0983346.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5309..7480
                     /locus_tag="NOB43_002520"
                     /pseudo
     CDS             5309..7480
                     /locus_tag="NOB43_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2260 a         1507 c         1359 g         2455 t
ORIGIN      
        1 ttgtcatgaa aatcttgtgc tccaccctta gtatttcctt ctggatcgtt tgtcgcacgc
       61 atcatgacgt atactttctt attagggaaa tcacgcatat tgaaagatac atgatagcca
      121 acatttccta aagtattata agcttgattt acgtctggtc tataaatccc atcagctctt
      181 actctagcta gttcttttcc agtattgtag tccataatga aaatatactc gtatttataa
      241 ttagcaatgt gccatccagc tacatgcaag tttgcgtttt cgatttctcc gaactgatca
      301 atgtgggcgt aatttgttcc atctgtcagc gtagaatttg cagcacctgc tcgagttgga
      361 tcaattactg gtttatcctc cgaagtagtt ggattatcat ccgtaaaacc atgagccaaa
      421 tcataggcta gtttttcttt acttacacct atttcagaaa gataaccgta aggatctgta
      481 tgatcgcccc aaatattttg tgttacccat aaatgcgatt tgattcctgg ttggttataa
      541 ggagtgtcta atgttaatgg aataccatat ttcattgctg aatctcttgc caattcaacg
      601 tatactttat agttcttttc aaaagtttct ttatcatgtg tgtgttgtaa ctcgatttgc
      661 acaggacttt tggctcacga ggttgtccta ctctacatct tgctgataga tatgctgaaa
      721 ggaaaacacc aacattatgt tttgcttttt cagctagaac gagacaagca ggaatacctt
      781 tagaagatat caaaggtttt ttaggtcata aagatgtttc cactacacaa gtctatgccc
      841 atatttctcc cgaagtgaaa aaaagatcaa tgaatcaact agaaaactat atagaagagc
      901 aaataaaaaa gcactcaaat tgagtgcttt tttaagctca ctatcactaa aactatcact
      961 aattttattt ataagcgaac atgtttctat cactgatttt ttaaatctag cgaaaaaccc
     1021 ttatcttaaa ggcgttcgtt caattctttg gcaaggtctt caaagcctgg cttgcctaga
     1081 agtgcgaaca tggttttctt atagctcatg tagaaaaatt ttcttgatga tgattttatc
     1141 catcaattga gattgactgt tttgctctcc tatgatttca gctatgattg tccgattttg
     1201 cggttttctt cttaactggt agttgatttt cccagtttcc atcaactcgc taagcatatc
     1261 cacgactccg ccaaatccgg tctttttcgt aataaaacct agtgctacca ttcgttcatc
     1321 tagatttttt gctgtaatcg tcacaccagt aatgagcgag tgctgtaatg tttgggccag
     1381 ctcttccatc ccttcagcat tggatacgac ggaagctgtt ttgttaatag gttcttcgtt
     1441 tatttctttt ggttctttcc tctccacttt cactgtttga cgaaggacat ctagttcttg
     1501 caagagcgtt tcgtattgtt cttgggtcag catcacgcca gctacttttt cacgattaaa
     1561 tatatatacg ccagttcccg cgtctcgcgc ttgagcaaat acatccatcg gcgatcgttt
     1621 cacttctgtg atcgaagatg tgggaacttc taatttcttt aattccaatg gatttcctcc
     1681 tttactaatc gctttttatt atagcacaga ctgacttgtt ttgatctttt ttccaaaggt
     1741 tttatcggtt tttgcctaac cagtaattga tatcggtaag aagtctttcg ataccaaatg
     1801 aaggatggta cagatacgtt ttttgatctt cgttatggtc tagtggaaaa aaatgatcga
     1861 tgatcactag atctgcatac cgaggcggct tatttcgagt acatacatgt atagagatcc
     1921 gttttcgatg tcttagcgtt ttgttcagta ccccagcaag tcttcttgct tcttggtgtt
     1981 catagcgaaa aaaaaagacg attttcactt caggagggtg gacatctaaa taccctcgtt
     2041 cctggagtgt tttcagtaaa agcatccccc actctactgc ggggtgtgca agtgcttgtt
     2101 ggatcgctag ccgaaattga tatagtttat ctttggaatt gggaaatttt tctaatgttt
     2161 cctgataata acgaacttct tctatcagcc ggtcatggat accaattacg taacgaagtc
     2221 attcttggta aagtactttt gtcagctttg atttgctttc gctctcaaat tcgctattca
     2281 gccaaaacag cgaatcaagc ttttcagtca caatcgtcaa tttccgatag tcttgtgtct
     2341 cttctatccg tttccaccgc ttttcagtaa tctggttaca gctcaagcgc aaaattgcta
     2401 gataattttt ttcttttatt ggcaaaatct gctcctctct aaatagcaat tcaggaaaca
     2461 attcaaagaa tagtgttcga ctgtctccta aaatctcgat ttctgccgga tcctttcttt
     2521 gcttcaataa ttggatgaac atctcagaaa aggactgctc tccatcatct gcaaaaaaat
     2581 gcggaaaatc tttcaaaaag caaaacagca gatatcttac ttttctttct gaaccaaaga
     2641 tctgtgcttt tttataagaa aaagaaaggt ggtactcgcc aaaccacttt ctcaatcgct
     2701 cttgcgtaga acgatcgtac ttctgctcgt aaggttcatt caatagcaga tttttcagta
     2761 aacaaaacgg gggtgattgg atcagaaaaa caaacaagag ataaggttcg ctatatcctt
     2821 gatcataaac taactgaacg gttttcttat gaagaatcag ctgaatggga cagtcgcttt
     2881 ccgccaaacg tttcagatgc cgatccactg ttttaacatc gattttcagt tcttcagcta
     2941 aatcagcttt tcgccagatc aaatctttca ttagattgat tagtgaaaat aaattctgtg
     3001 cattttttga taatagtttt tgccatctca tcgatcattt ctcacctgat ttctaaacat
     3061 attgtttgat caaaatgggt tcactcctaa aaagataaaa aactcccttt ctatttattt
     3121 aaatacgcaa atcttcctca ttatttttta ttttactcaa tttaatcgta ttctcatttc
     3181 aaaacgaatg tactttaaaa aaacataata agatcacttt gcttgtagga tgtattccct
     3241 tccattacaa tgaaataaat agcgatttta tgagaaggtg atgtgaaaat ggaagaaaaa
     3301 atagaagaat ccaaacaaaa aatcgatcag ttgatataag aattagaaaa agcggtcatc
     3361 ggcaaacgtt caactatcca attgatgatc gtggccctat tagcaggtgg tcatgtctta
     3421 ttcgaagata ttcccggtgt aggtaaaacg ttactggtca aagcactagc aaaagctgta
     3481 cagggaacct tcagcagagt ccaatgtact cctgatctgc tgcctagtga tattcttggt
     3541 ttttccgtat acaattcaca atcaaaagag tttgaatttc gtccgggacc gatctttacc
     3601 acgatcttgt tagcagatga gatcaatcgt acgactcctc gtactcagtc agcactttta
     3661 gaagcaatgg ccgagaatca tgcaacgatc gacaacaata cataccctct agacaatcat
     3721 ttttttgtct tagctacgca aaatccaatc gagtacgaag gaacatatcc tttgccggaa
     3781 gcacagctcg atcgtttttt attccgacta caaatcggtt atccttcttt tgatgacgaa
     3841 cttttgctac ttttggataa attcgaaaaa gtgttggata acttaaatga agtattgaac
     3901 agttatgaaa tagaagaaat aaaaacaaat gtggcgaatg tctttgtcag tcccgaagtg
     3961 gcatcttatg ccttgcagtt agtgtcagca acaagaagtc atgctgccat ccagcttggc
     4021 atcagtccac gaggaagcct ttcctttatt caggcagcaa aagcttatgc tttaatccat
     4081 gggagaaatt acgtcacgcc caaagatttg caggatttag ttccttacgt gttttcccat
     4141 cgcctgattt tttacgatcg ttcattgaag gaagacgaaa agaaacaaat cattcatact
     4201 cttgttgcac aaattcctat tcctgtgagg tagattgagg tagacaatgg aaaaaatcaa
     4261 agattatttc attaattttg tgttatttct ggtatatttc atcattgtgc tttttgctct
     4321 tgtattcaac aattctttag gctggttctt gttggccttt tttactcttt atgtatcatg
     4381 gagcttgatt tcattaagca gctttctaaa gaaactttcg gttacttgta cattgcagcc
     4441 actcgtttat cgcaaaaaaa gtatgcaggt tattttttcc atagcaaaaa agagaacttt
     4501 ttctttacct ctccctcgtt tacaaatcgg cttcccagca atctttgcag aaaaaaacaa
     4561 gagattttga ttcttacaaa taaaccgcaa gaagtccaat tgctttggca gccaaaagaa
     4621 agaggatgcc atgaaacatt aactgtcatt tttacagcct atgatagtct aggacttttc
     4681 agaaaaagtg caaaaagaga gatctctttt cctgtgactg ttctgcctgc tttttgtaag
     4741 attcaagcag aaaaattaca gagagttctg gaaaaaaaac agcagctgaa cgcgtaccaa
     4801 agaggtcttg attttcggga acatcgcgct tatcgtccag gtgattcttt caaccgaatc
     4861 gattggaaat tgtctgctca tactcaagag tggttatacc gtgaatacga ttatcaagaa
     4921 gaagaatgtt ctcctctttt ttgcttttgg ggttcgccca gtccaaaatt tgaacctctg
     4981 ctagacttgt atttttcttt atggcatttg agaaaagaaa agcagccgga acttctgata
     5041 ttaggcaacc gcgcctttca tggcaaagac cccggtcata cctattttgc ttctttggaa
     5101 gctggcgatg agaaaacttt tttcgcacac ttgaaaaaat atgcaaaaaa acaaatcgtc
     5161 ctctttgttc ctgagaattc tcctgaagtc tcagaagcta ttgaaacatt gtcaaaagat
     5221 cgaacggttt atcttgttta tttcgtagaa aaacaactca tggtccaaga aaaagacaag
     5281 atatgttcat tgccaggagg tgaatggatt gacgattaaa cgggaaaaat ggctgcgtgg
     5341 cgtttactcc tttgtgatac taagtgtagg tgctccgata tttgtagtag ctaatcaatt
     5401 gcaaaacagc taccttctta tcctaactat tggtgtccta tgccttattg tctgctgtat
     5461 tcctaaaaaa tgggtacgtt tgctgctttc tttgccagta atgataggtt gtttgttttt
     5521 atattttcct tcgaagacat tttccatatt atggatctta cagttttttt cgtcagttac
     5581 agaggaattc ttccatctat cccaaggtaa actttattat ttgccagaaa agacagcttt
     5641 ttttctcata atgttgctga tctatttatt tattacattg accgtggatt acgactattg
     5701 gtacgcaccc tttctttctt tgatggctta cttcatgatg cttaccgttt ttcggaaaaa
     5761 agatttactg tacgaaatga ttgcggtagt aactgttttg ttcgtgtatc tggcagcaag
     5821 gcaatttttc tccatccggt tgttgtcgag aaacactcga ttccagtcat tgactacagt
     5881 tctgcttatt tgtttcttaa cttttagcgc tatcttgcct ttatatcttc cgaaagtaca
     5941 ccaatctctc gaggaaacga gtgaaccgat ccgagaatat cttaatgatg aagggcttta
     6001 tgacacactc catgagtatc aattaaccgg aagtgcaaga acaggcttca gtgagaatga
     6061 tgaacagctt ggtggacctt tatatgataa tggcgaagtt gtttttacag cgaaccaaaa
     6121 aggaaatggc tattggaaga tcgaaaataa aaatcattac accggttctg gatgaataga
     6181 agatcaggac gcacccatcc aaccaatcca agaattccct gttgacatca cgagctacca
     6241 aaccgttata gaagacaaag aaaacattac attgacccta aaaaaacaag ctttcttacc
     6301 ttatccttat ggaaatacta ccttgactga tttttcatta gctagtggac aaacgcttta
     6361 ctatttgcct gaaagccagc gattcattcc tgtcccgaat gaatcgacac gttctgcaac
     6421 tttacaaaca gaaaggttag tttttacgag agaagaatta aaaagcagtc agttaaaagc
     6481 tgatgattta gaaaatcagc agacaaatct tcaattgcca aaaagtttgc ctaaacgtat
     6541 tgaggacttg gcggtcgaat tgaccaaaaa tgaagcaact ttaattcgta aagtcgaagc
     6601 tgtctaacag tatttaaaaa caagcggaaa tttccgctat tccaaaacgg ataccgggca
     6661 tactccaaaa gaacacgatt atgtggatta tttcctcttt gattcaaaag tcggctattg
     6721 tgacaacttt tcaacttcta tggtcgtcct tcttcgaaca cttggtatcc cagctcgctg
     6781 gacaaaaggt tttacaaatg ggctcagaac aggcacagat aatcaaggga atgaggaata
     6841 cagcattctc aatagtcatg ctcattcttg gccagaggta tactttcctg gatttggctg
     6901 gcttccattt gaaccaaccc cttcatttgc caatccaatg ggttcacaac cagttgctga
     6961 aacaaccgaa accgtccagc ctgctatcga acaaccaaat gaaagcgaaa atatggcaga
     7021 aactatttcc agtgagagat ctgaggtcat tccatcagaa gaaacaacac tcacaccagc
     7081 ttataaaatc gtcttattca gccttggagt gtgtttatcc gtcttgttgt tctttctatt
     7141 gttattcaga aaatctctgc gctggacaag ttatcttatc tatcttcatt tttttgcttc
     7201 tactaatacg attgcatatc aaaaacttct taaccctttg gaaacattgg taccgcgcaa
     7261 acccgcagaa tctttgcagg aatatagcct gcgaatagaa caagaattca agctagatct
     7321 gcgtttcatt cgattaacta ctcaatatga agcagaaata tatggacgac aagcagatcc
     7381 ggtaaaattc gataaaaaaa cctatttaga aataacgcat ataataagaa aaacggtata
     7441 caaaaaaatt ctgacaaaag ggagccgctt caaaaaataa gataaaattt ctggagaatc
     7501 tacttctcga atgccgagaa ccagctgatt gagtatcgat tactcgaaaa aaaggttgtg
     7561 acacgttttt tgtcacaacc t
//
LOCUS       DAIGTA010000089         7497 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.095, whole genome shotgun sequence.
ACCESSION   DAIGTA010000089 DAIGTA010000000
VERSION     DAIGTA010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.095"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..115)
                     /locus_tag="NOB43_002521"
     CDS             complement(<1..115)
                     /locus_tag="NOB43_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0983347.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="NOB43_002522"
     CDS             246..698
                     /locus_tag="NOB43_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983348.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="NOB43_002523"
     CDS             712..1401
                     /locus_tag="NOB43_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983349.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPILPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="NOB43_002524"
     CDS             1526..3877
                     /locus_tag="NOB43_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HCI0983350.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="NOB43_002525"
     CDS             3957..4352
                     /locus_tag="NOB43_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983351.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="NOB43_002526"
     CDS             4677..5294
                     /locus_tag="NOB43_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0983352.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="NOB43_002527"
     CDS             5335..5634
                     /locus_tag="NOB43_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HCI0983353.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="NOB43_002528"
     CDS             5668..5835
                     /locus_tag="NOB43_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0983354.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6485)
                     /locus_tag="NOB43_002529"
     CDS             complement(5880..6485)
                     /locus_tag="NOB43_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0983355.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            complement(6745..7425)
                     /locus_tag="NOB43_002530"
     CDS             complement(6745..7425)
                     /locus_tag="NOB43_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HCI0983356.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
BASE COUNT         2527 a         1101 c         1444 g         2425 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattttgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tccttccatc
     6421 attgccaatt gtcgatccaa attttgatct tgtgaagata ctcgaatata gccaattttt
     6481 cccataaaaa actccttttt aaaagtgata taatttacat gtaaaattta cttgtagttt
     6541 tactgctatc atagcatttt taaaaataaa ttttatgtag acttaaaatt tacttcatgg
     6601 agggtttaaa tggatgaaat caaaagtaac aaaaaagcat ttggcattta tttaggagaa
     6661 cctagtacag aacaattaaa ccaatttttt ggttctgttg cgaagtttga aaatcaaacg
     6721 cgccctctct gaactccaaa tatcttaggc tgttattccc attaatacct tgatttcagt
     6781 agacaccgaa aagccgaaga gcgttccatt tcttcggttc tttttatata ttcctcgaat
     6841 ggtctccatg cccttaatcg tggaagaggc tgtacggaga ctttgataaa atttatttcg
     6901 tcgtttaata ggtcgatggt cttgttctat taaattgtta agatacttca cagttcggtg
     6961 ctctgtctta gtatataaac ccacactctg taactttcta aaggcggagc caagagaagg
     7021 tgctttatcg gtcacaattg ctttcggctc accaaactgt ttatggagtc gttttaagaa
     7081 agcataggct gcttgcgtat cccgtttctt tcgtaaccag atatctaagg ttaagccgtc
     7141 cgcatcaatt gcacgataaa gataatgcca acgtccctta attttgatat aggtttcgtc
     7201 cattttccat gaatagaagg attgtctatt tttcttcttc caaagataat agaggacttt
     7261 gctgtactct tgcacccaac gataaatcgt agtatgacaa acatttattc cacgatcata
     7321 taacaattcc tgaacttcac gatagcttag attgtaacgc aggtagtaac caacagcgac
     7381 aataatgacg tcttttttga attgtttgcc tttaaaatga ttcattactc tgtcctctct
     7441 gtcttttttc tcaattttac actaaaatag attttttgga aaactttgca acagaac
//
LOCUS       DAIGTA010000090         7337 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.096, whole genome shotgun sequence.
ACCESSION   DAIGTA010000090 DAIGTA010000000
VERSION     DAIGTA010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.096"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(482..907)
                     /locus_tag="NOB43_002531"
     CDS             complement(482..907)
                     /locus_tag="NOB43_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983357.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1281..2252
                     /locus_tag="NOB43_002532"
     CDS             1281..2252
                     /locus_tag="NOB43_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0983358.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2284..3681
                     /locus_tag="NOB43_002533"
     CDS             2284..3681
                     /locus_tag="NOB43_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0983359.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3840..4463
                     /locus_tag="NOB43_002534"
     CDS             3840..4463
                     /locus_tag="NOB43_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983360.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            5212..7305
                     /locus_tag="NOB43_002535"
     CDS             5212..7305
                     /locus_tag="NOB43_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0983361.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         2503 a         1230 c         1489 g         2115 t
ORIGIN      
        1 aaaaccaaac gacgggaaag aaaaattact acgtgatgta gaataagcct ttctatcgtt
       61 tggttatttt atattcaaat atttgaaata aataaatctt tactctttga tttgtaaact
      121 gaaatgatcc actgtttgtt ttactgatga agcttgatca aaggaagaag ctgagtttga
      181 agttcataaa aatcagccat agtgagtttt gcttggattt gtttatcttc ttctactttt
      241 tacataattt tgaacaggat aagattcaaa tgttttaaat gaatctttga ctagtttgtg
      301 acagttgtcg catatgctca agcttccttg gtcattaaat tctgtatgga tatttttgtt
      361 gttattacat gtacaataat caggactatc gatcatccat ttcgtctcct ttacaatcat
      421 cttgcttctt tactatagca gaaaagaagg ggagaaacaa aagaagatcc aacagacggc
      481 actatagact gtagatgttg ccatcctcat ccttcaaacg gtaattaccg atttttgtaa
      541 atatgactgt tgtttctttt ttattttctt ttcctgaaat aatatattcg tcatctttgg
      601 tagtgatctt gatatctgtc agcactgttt tttcttcaga tgattcagaa gaatcagttc
      661 cttgtgtctg atacgtgcgt gtccattcca tttttttatc tgtaaatgtc aactgtcccg
      721 cggataaatc catatcttta cgtactttta gcgtatatac actgttggtg gtatctgctt
      781 tttccgcttt taagacagaa gaatcggttg tttcgtccga ggattggtca gagccgccaa
      841 acaaatcaca gccagtcaat gtcaaaagtc ccgcagacaa aataaatagt acgattaatt
      901 tcttcaaaat acttccccca tttgatagga taaagaaatt ataccattgg aatgtaaaac
      961 ttcaaacgga tggaagagaa aaacgcacaa aacacccaca aatagagtaa attttagaat
     1021 aaaattttaa aaaggcaaaa aatccgccac tttcagaaag cgttttaaaa aagtgttgca
     1081 atcttttaaa aaaatgctat attaaaaatg aaccggttca aatacttgtt taagtataat
     1141 taatagtgag aggaagttgc tctactgaag actttagtta tatggatatt gatgacaagc
     1201 aacactatgc aaagaatgcg gtcatcataa tcgaacaaca agaaagagaa atcaaatgta
     1261 actggcagga gtgagaatgt atggcatcga tccgtgatgt ggctaagatg gctggtgttt
     1321 cagtgggaac agtttcccgt tacttgaatg gtcagcaact gaaggaaaag aacatgaaaa
     1381 aaatagcaga agcgatttca gcgttggact ataaagaaaa catcattgct aaagggttga
     1441 agaataatcg aagcttctct attggacttt tgataaacgg gatttccagc cgttttgggt
     1501 cggaagttgt ctcagggatc gaaagagtag ctgaagaaaa tgggtatagc ttattattaa
     1561 gcgggtttgc cgatcagcca gaaaaaattg aacaaaaaat tgaatacctg atgaagcatg
     1621 tgatcgatgg gctgattgtc ttcttatccg aagaagagtg gtctggattt gaaatgctca
     1681 caaaaatgag tattccagtt atcgcattga attgtccaga aggaccagca ggtattgata
     1741 caatattagt gaatgatcga gaaagtgtag caaaagtgat cgctcatcat ggtgaacaag
     1801 gacataaaaa aatcggattt attgctgcca ctcaaacaga ctacgtagca agagaacgtt
     1861 tagcaggagc caaagaagcg gtccaaaatg atccatcgat ccaattagag gtctttacag
     1921 gagactattc tagaaaaagc ggctattacg gggcaaaagc attattagaa aaaggggcaa
     1981 ctgctatttt tgtcagcaat tacaatatgt cgattggtgc catcgaatgt ttcaatcaag
     2041 aaggtgtcag aatcgggaag gatattgcgt tcagtcacta tgattattta gataaaaacg
     2101 atctgagtat ccttccgaaa atcacgatca cgccaccaac agataaaatc ggggaacgag
     2161 cagcagaaca gctgttaaaa cgaatcaaaa aagaagagga agaaaatgaa aaagtgattg
     2221 tgatggaaaa tatcatacat ggaatcaact aaaacgaact aaaaaagaaa aagaggtgct
     2281 ttgatgaaaa aatatcaatt tccagcaaat ttttggtggg gttctgcagc aagtggccca
     2341 caaacagaag gaaggatttc aggcgatgga aaaggagaga acatttttga ttattggtac
     2401 aaaaaagaac cgcaaaagtt ctttgatcaa gtaggacctg aaaaaacctc gcaagtttat
     2461 acgaagtatc aagaggatgt acagttgatg aaacagactg ggcataattc atttcgaaca
     2521 tctatccaat ggagccgttt gatacctgat gaatctggaa caatcaacga agaagccgtt
     2581 cgtttctatc atcgttattt tgatgagttg attgaaaacg gtatcgaacc ctttgtgaat
     2641 ctgtatcatt tcgatatgcc gatgtatctg caagaaaaag gcggatggtt gaaccgagaa
     2701 acggttgaag cctatgaaaa atatgccaaa agttgttttg aattgtttgg ttcgaaagta
     2761 aaaaaatggt ttactcataa tgaaccaatc gttccagtcg aagcaggtta tttatatcga
     2821 tggcattatc cagaagagtc agatatgaaa aaagcgatcc aagttggcta tcatgaagcg
     2881 ttggcttcag cgttagccat caaatcttac catgaaatgg agcaaggtgg tgttattggt
     2941 atcatcttga atctgacacc aagctatcca agagacgaat caaaccctga agatgttaaa
     3001 gcagcgcaaa tagcagatgc gttcttcaat cgttcattcc ttgatccagc tgtaaaaggc
     3061 gagtttccaa gtgaattgat tgagatagta aaagaacttg atctcatgcc tgtgatccat
     3121 gcagaggatt tgacggttat caaagaaaat acagtagatc ttttaggtat caattattac
     3181 cagccacgcc gggtaaaagc aaaagaaaca ccaatcgata ctaaaaacgg tccaatgcct
     3241 gaggattatt tcgacaatta tgaaatgcct ggtcgtaaaa tgaatcctta tcgcggatgg
     3301 gagatctatg aacaaggaat ctatgatatt ttgatcaatg tacgagatca ttatggaaat
     3361 atcgactgct ttatttctga aaacggtatg ggtgtagaaa acgaagcacg atttatcaaa
     3421 gaagatggca tgatccacga tgattatcgg atcgaatttg tccaatctca tctgaaatat
     3481 gtccatcaag ccattcaaga aggtgccaat tgtttaggct atcatatgtg gacatgtatg
     3541 gataactggt cgtggaccaa tgcatataag aatcgatatg gctttatttc agtagactta
     3601 gcacaagatg gaaaaagaac aatcaaaaaa tcgggtcatt ggttcaaaga cgtatcagat
     3661 aaaaacggat ttgaggctta agaaagaata gttgagagca aatgcgtgaa attctccatt
     3721 cttaccattt tgtgaaaaag aagttcaatt atttacgatc tttttcaact tttttgtctt
     3781 tctatttcat tttttgtata taatagaata gtcaaaatta aataggagtg gaggaaagca
     3841 tgaggaaaaa aagaccgttt cttctctttt ggttattcgg ttttttctta ctgcttattt
     3901 tatccgcagc attttcagga aaaatgacag cagatcttgc tcagaaagaa acagaaaaaa
     3961 tcgtagcaag caaagaatca gtagataatt tcaaaaaaga attctcaact tattggtggg
     4021 cggagtataa aataactgcc aattacgaaa aaggcgaatt ggacatttat ttgccaaaag
     4081 gaaaagaaga aaatcaattt attaatatcg atgacgtact tagtgcgatt tctctcagac
     4141 aatatcaatt taaagacaag catttgaccg ttttgctttt gactcatgat ggcgacaaag
     4201 tagcccgttt gaaaaatgga aaagtgatca ccgcttattc tgaaaaagta gacaaaaaag
     4261 tggtcgccga tcgtttagcg gaatggaaaa agacaaatga acaagtcaag aaaacaactg
     4321 tctcttctca aaaaaacgag tcgacaggaa caagtccttc agattctggc agtggacaaa
     4381 cgataacggg aagtgaagaa aatcaagcct caattattac gaatgagtca tcacaaggac
     4441 aatatcaatc ctatggacaa tgaaaaacag aggttgtgaa atcagcgttt tgacctgagt
     4501 attagagaaa caaacggcaa aatagttcct catattttgc cgttttttga gctaataccg
     4561 aaggtcagct gattgaacac cgtgtatcaa gaggtcttga gcctgccgtt taactctgag
     4621 ccacaaggag caatttcaaa aaatagctcc ttatattttt cgtttggttg ggcttattac
     4681 cgcagatgca agcttttgaa caccgtttac caagaggttg taaaattagc gtcctgacat
     4741 aatctaatac cgagggtcag ctgattgaac accgtgtatc aagaggtctt gagcctgccg
     4801 tttaactctg agccacaagg aacaatttca aaaaacagct tctcatgttt tataaatatt
     4861 gtgacttgtg gccgaggagt tggcaggaga acaccgttta aggaagaagt tgtgaaaaag
     4921 ctgtcctgca tcaagaaata aggagctgcg acaagaattt tgtcacagcc tctttttttg
     4981 tacgaatacc gagaaactgg cttttgaata ccgtggagtg aagcggtcac cacaagactt
     5041 ttatctcttc attagtttaa tcgcttacat cgcagcggtt ttatgctgtg aaaagtggac
     5101 ggaataatct ttagaaagaa taaaaaaatc ttaagataac aactttttta ggaaattttc
     5161 atttttcagg agcaaaataa gaaaaaatgt gaatagagag aagtgatata cgtgacacaa
     5221 cttaaaaaat tgtgccaaaa tcgtttagca atcgttttga cagctgtttt ctttttctgg
     5281 ctgaagacga tcattgccta ctatgcagat ttttcattag gtgtggaagg tacgatccag
     5341 tactttatct tgtggatcaa cccaattgcg actaccttat tgttttttgg cctttctttg
     5401 tatattaaaa agccaaagcc agcgttagct attcttttga tcattgatat tttaaatacg
     5461 cttttgttgt acttgaatat tattttttat cgggaattca cagatttcat tacagtcaaa
     5521 tctgtattag gcttttcgaa agtgtcgcaa ggattgtcag gaagctcctt ttctttgatg
     5581 aagccccatg atgtcatcta ctggctggat atcgctgtgt tcattgggct actggtttgg
     5641 ttgaaggtca agaaaatacc tatcaaaagc aaccctgtcg gcaaaccgat ggctatcgct
     5701 gttacctgtc tttcagggct tattttttca ggaaatctag cgctgagcga agccaaccgt
     5761 ccacaattgc tgcagcgaac atttgaccgt tcatatattg tcaaatatct aggaatcgat
     5821 gcgtatacta tttatgacgg aatcaaaaca ggaatgacta gcagtgttcg cgcgcatgca
     5881 agcagtaatg ggattgatga agttttagat tatacaaaga aacattatgc agagccaaat
     5941 cccgaaacat ttgggatcgc taaagggaaa aatgtgatcg ttctccattt agaaagtttc
     6001 cagcagtttt tgattaatat gaaggtagac ggacaagaag tcacaccgtt tttaaatagt
     6061 attttccaga atcaagcaac gatcagcttt gacaatttct ttcatgaagt aggacaggga
     6121 aagacaagtg atgctgaaaa tatgttggaa actggcacat ttggtttacc tcaaggctca
     6181 ttattcacag aacttgggtc agacaatgtc tttcaagccg caccagcgat ccttggacaa
     6241 aagcaaggct atacaagcgc tgttttccat gggaatgtag ctagtttttg gaatagagat
     6301 catgtatata aaaacttagg ttatgacaat ttctttgatc gatcttattt tgatgaatcc
     6361 gacgaaacgt taggttatgg gatattagat aaagatttat tcagagaatc tgcccaatat
     6421 cttgagcatc tacaacagcc gttttacacg aaatttcttt ccgtaaccaa ccacacgcct
     6481 tattatacgg atgacaagaa tttcgacttt ccatctttga atactggcaa tagcacagta
     6541 gataattatg ttcgaacggc acattatctg gatcaatcat tggaacaatt ttttacgtat
     6601 ttgaaaaaat ctggtattta ccaaaattca atctttgtga tttacgggga tcattttggg
     6661 atctcgaata cagataataa agatttagca agcgctcttg gtaaagatcc agatacatgg
     6721 gatgaatttg acaacgcaca gatgcaacga gtgccattga tgatccatat gcctggttat
     6781 actaaaggga cagtcaatca tgaatacggt ggagaaatcg atgttttgcc gacattacta
     6841 catctattgg gaatcgatga taaagattat cttcattttg gtacagactt attatcttct
     6901 cagcatgatc aagtagttgc ttttcgaaat gggaactttg tgacacccaa atacaccgtc
     6961 ctaggaggaa aagcttacaa taatcagaca ggagaaatca tcgatacgaa agcagcagga
     7021 atcgatgagg aaatctccaa agatcaggaa aaagtcaaga ctgcgttaag tctttcagat
     7081 aagctgaatc aggaaaatct cttgcggttt tatgtgccaa acggatttga gacgattgat
     7141 ccgaaaaaat atgactataa aaatgaagcg gaacgtaatg aagcaatcga aaagcaaaaa
     7201 ggcgaacatt cgacaagtgt cttttcaaaa aatggtaata aaacaacaac caacttatat
     7261 ccagtaacaa gaacagacgt tgaacagcaa aaaaataatc aataaacaat caaaccaacc
     7321 ttcagtagtt agacaac
//
LOCUS       DAIGTA010000091         7190 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.097, whole genome shotgun sequence.
ACCESSION   DAIGTA010000091 DAIGTA010000000
VERSION     DAIGTA010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.097"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(32..1438)
                     /gene="lpdA"
                     /locus_tag="NOB43_002536"
     CDS             complement(32..1438)
                     /gene="lpdA"
                     /locus_tag="NOB43_002536"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCI0983362.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            complement(1446..3089)
                     /locus_tag="NOB43_002537"
     CDS             complement(1446..3089)
                     /locus_tag="NOB43_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HCI0983363.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            complement(3114..4091)
                     /locus_tag="NOB43_002538"
     CDS             complement(3114..4091)
                     /locus_tag="NOB43_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HCI0983364.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            complement(4094..5203)
                     /gene="pdhA"
                     /locus_tag="NOB43_002539"
     CDS             complement(4094..5203)
                     /gene="pdhA"
                     /locus_tag="NOB43_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HCI0983365.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            complement(5664..7088)
                     /locus_tag="NOB43_002540"
     CDS             complement(5664..7088)
                     /locus_tag="NOB43_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI0983366.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
BASE COUNT         1855 a         1612 c         1297 g         2426 t
ORIGIN      
        1 tttcagttgc gtttcgcctg tattattcaa atcaaatatg gattggtaaa cctaatgcta
       61 attccgaagc atccatgacg atttcgccaa gagatggatg aggatgaatc gtcaaggcga
      121 tatcttcagc attcattcct gattcgattg ctaaagctaa ttcagagacc atatcacttg
      181 cgccgactcc accgatttgc gcgccaataa gcacgttatc ttcgatcgtc gtaactagac
      241 ggatgaatcc ttctgtttta ccaagcgata atgcccgacc gttccctgaa aatgggaatt
      301 tatatgcttt tgcttcgata ccagcatctt ttgcttcttt gatcgtcata cctacagaag
      361 ccaattcagg atcagtgaag gctactgccg gcattgcttt ataatctaca gctacttttt
      421 tgccagagat tgcttcagca gcgatttttg cttcataact ggctttgtgt gctaatgccg
      481 cccctggaac gatatcaccg atggcataga tgttaggtac gttcgtacgt ccttgtttat
      541 ccaccgtgat caatcctcgt tctcctactt cgacacccgc ttgttctaag cccatatcat
      601 ctgtattcgg acgacgacct acagtgacca tcacataatc agcagtaacg gattcttctt
      661 tcccgtccac tgcatatttc actgtcacgc tgtcaccgtt atcgactgct tctttcgcca
      721 ttgcattcgt tacgactgtt acgccttttt tcttgaaatc atcttctact aattttacta
      781 gatctttttc gtaagttggt aaaatttgtg gtgagccttc aagaatcgtt acttctgctc
      841 ctaagtttgc gtacgctccg cccaattcgg caccaatcac accgccaccg atgatcacaa
      901 atttcttagg tacttctttc aatgctaatc cgccagtaga atctaacaca cgtcctccga
      961 atttaaatcc tggaatctcg attggacggg aacctgttgc gatgattgcg ttattgaacg
     1021 aataagtttg agctgaatct ggatgaatga cgcgtagtgt gtgatcatct acgaagaacg
     1081 cttctccttc gattgtttca accttatgtt tttttaatag gaaaccaaca ccagaagtca
     1141 acgtatggac aactttgttt tctttccatt cttgtgtttt tgcaaaatct agtttgacgt
     1201 tttcactagt tactccaaac atttcagaat ctagtgactc ttgataatgg tgtcctgcag
     1261 ctatcagtgc ttttgaagga atacagccga cattcaaaca aacaccgcca atatactctc
     1321 tttcaatgat tgctactttt tgtcccattt cagcagcgcg gatggcagct acatagccac
     1381 caggtcccgc accaattaca actgtatcta attctacagc aaaatctcca actaccattt
     1441 gtttatcatc cttccatcat taatagctct ggatcagcta aaagacgttt gatattattc
     1501 attgcttgtt gcgcagttgc tccatctacg atacggtgat cgaaacttaa tgacagtttc
     1561 atcacacgac cgacaacgat ttcgccttca gcatttacga ttggttgttg tgcaatcgtt
     1621 cctacaccta aaatagctac ttctggatag ttgatgactg gtgtaaacca accgccacct
     1681 acagatccga tattgctgat cgtaattgtt ccattgcgca tatcttctgc agatagtttg
     1741 ccgtcatgag ctaattttgc tttctcattg atttcgtctg caatagcaaa cattcctttg
     1801 cggtctgcat ctttcacatt tggtacatat agtccgtgat ccgtatcagt tgcaataccg
     1861 atattgtagt aatgtttata aacgatttct tggtttgcat cgtcgataga tgcattcaat
     1921 actgggtatt tcttaacagt cgctgttaaa gctttcacga catatggcaa gaaagtaagt
     1981 ttcgtaccat ttgcagcagc aacttcttta aatcgtttcc gattatccca tagtttagac
     2041 acttctactt catcatgcaa tgtcacgtgt ggagctgtat gcttactgtt gaccattgct
     2101 ttagcgatag ctttacgtgt tggcgtcatt gctacacgtt cttccaagtc tcctaagttg
     2161 gacttgaatg gttttgctgg tgcagctggt ttgctttctg ctgcaggagc tgcttctttc
     2221 ggtgctgccg cttctggcgc ttctgatttc gctggtgcac tgcttggacc acctgccaag
     2281 aagttttcga tgtcctcttt tgttactctg ccaccttttc cagttgcagt tacttgtgag
     2341 atatctacat ctttttcacg ggcaaattga cgaacagatg gcatagccaa tacacgttta
     2401 tttggatcgg cagcttcaac gacacttgct gaacctgatg tttccacttt ttcttttggt
     2461 gcttcagctg atggcgcact agttgacggt gcactattgt gtccaggagc atcgatttct
     2521 actaatacat ccccaacatt tgctacagtg ccttctggaa caatcacgtt tttaactgtc
     2581 cctgtgacag gtgacggaat ttcttctact gatttgtcat tttgaacttc tagtaatgta
     2641 tcatcttcat tgatcgtatc tcctggtttg acgaaccatt tgacgatttc accttctgcg
     2701 attccttcac cgatatccgg taacttaaat tggaagactc cttcgcttga cgatccagct
     2761 gattctgtat caacagtggg ttcagcagcc ggtttagctg gagtttggga ttctgcggct
     2821 acaccactgt ccccttcatt gtcttcgtgt cctggtgcat cgatttctac taatacatcc
     2881 ccaacatttg ctacggtacc ttctggaaca atcacatttt taaccgttcc tgtaacaggt
     2941 gacgggattt cttctactga tttgtcattt tgaacttcta gtaatgtatc atcttcattg
     3001 atcgtatctc ctggtttgac gaaccatttg acgatttcac cttctgcgat tccttcaccg
     3061 atatccggca atttaaattg ataagccatg actttgtttc gtcccttctt ttcttaaaat
     3121 tccgcgattt cttttacttt gtcttcgata tcttttgcat ttggcaacca gacattttct
     3181 gcttgtccaa atgggaagac tgtatcaggt gcagaaactc gtccgattgg ggcttctaat
     3241 gaaaggatag cgcgttctga gatctcagaa actacttgcg cggcaacgcc cgcttgtcgt
     3301 tgtgcttctt ggacaacaac tacgcgacca gttttttcca cggattgaat gatcgtttct
     3361 acatctaatg gcgcaactgt acgaagatca atgatttcaa cagatatatt ttcttttgca
     3421 agattgtctg ctgctttgat tgcttcacgc accattgctc cgtatgtgat aatagataca
     3481 tctgttccct cacgagtaac tgctgcttta tccaaaggaa cttcgtaagc ttcatccggc
     3541 acttcttctc ggaatgagcg atatagtttc atgtgttcta ggaaaacaac cggatcgtta
     3601 cttctaatag aagaaatcaa tagtcctttt gcatcataag ggttggaagg aatcactact
     3661 cgaataccag gagactgagc gatcaaacct tctaaattat ccgaatgcaa ttctggtgta
     3721 tgaacaccgc caccaaatgg cgaacgaatt gtgatgggta gatttctagt gccgctcatt
     3781 cgatatcttg tacgagccat ttgagctact acttcgtcca ttgcttcgaa aataaaacca
     3841 aagaattgga tttcaggaac tggacgaaat ccttctaacg caagaccgaa actcaatcct
     3901 gcgattccag attcagctaa aggagtatcg aatactcggt cttctccgaa cttttcctgc
     3961 aatccttcag ttgcccggaa aactcctccg tttttcccaa catcttcacc aaaaacaacg
     4021 acattctcgt cattttctag ttcaagtgct aaggcatctg tgattgcttg gatcattgtt
     4081 ttttgtgcca tgattatttc gactccttcg cttcataaat tgcaatttgt tctttgattg
     4141 attgtggaga tacttcgaac atgtttttca agaaatctga aaccttttgt tttggtactt
     4201 tgtcggcttc agcaatagct gctttgattt cttctttagt tgcttcgatg acttgttctt
     4261 ctttttcttc agaccaaagt cctttttccg tcaaatattt acggaagcgg atcaatggat
     4321 cttttttctg ccaatcgtca tctgtgtctt ttgtacggta gcgggttgga tcgtcaccag
     4381 atagtgtatg tggtccataa cgataagtca gtgtttcgat taggactggt ccatttccac
     4441 tgatcgccca ttcccgtgcc attttagata cagtatatac tgcaagcgga tccattccat
     4501 cgacttgaat accaggaatc ccagctgcga cagctttttg tgcaagtgtt tttgctgcag
     4561 tttgtttttc acgaggtgta gagatcgcat acccgttgtt ttggatataa aatacggcat
     4621 ttgcatggta agcgccagcg aaattgattg cttcgtaaaa atcaccttgt gatgaaccgc
     4681 catcaccagt ataagtgaag acgacatttt tcttgtttcg tttcttcaaa cctaatgcaa
     4741 caccggctgc ttgtacatat tgtgcaccga tgataatttg tggtggtaga gctttcaatt
     4801 cttccggata agaattacct gcagcatgtc ctcgagacca taaaaaagct tgagataaag
     4861 gtaaaccatg ttttactagt tgaggtacat cccgataacc tggaagaaga acatcttctt
     4921 tatcaaatgc gtaagcacta gccagctgac ttgcctcttg tccagcagtt ggtgcaaaaa
     4981 agcctaggcg tccttggcgg ttcagcgctg ttgaacgttg gtctaataca cgagaccata
     5041 ccatatgagt cattaattca acgagttcat catcggataa atcaggtact aaatctttgt
     5101 taactacgtt tccatcttga tcaagtgctt gatatactgg gaaatctgca ttgacttcat
     5161 ctagcagtgc ttggaagtcg atcggtgctt ttttgtttgc catttgtcac acattcctct
     5221 ctcatctata agaaaatctc ttcattctgc gattgaaaca gtgaataaaa ctgtatcact
     5281 atttaaccgt cttcattaat aaattatcat ggatttatga gaaatacaag ctaaaagcac
     5341 aaattttcac gatgaaagga aattatgcca atccgcatat taacagcatt agtgaataaa
     5401 atcacaataa ggaaagcgtt ttatatttca tctgcatttt ttctattttc taatcaaact
     5461 tacaaccatc tgtttctatt taaaaacgtt ggtgttatac agttttgttg caaacattta
     5521 ttttatttac acatcgtgaa cggacgtaca aataatggtt ttttcttagt ttctttatat
     5581 cgtattcttt ttccgaaaaa aaagaaacag cttgaaattt aaatccaagc tgttatattc
     5641 tttaatctat ttactttgtg aaattattct gttaaccact tttctagaat tttcatcttt
     5701 gaataaaaca acggtatttg gttttcatcc agcctactgt aattgattct gattccattt
     5761 atatcttgcc caaaaagtag acttggtgca attccaagac ccatatctac tactttttct
     5821 gctagttcgg ggtctagttt tttcccatcc caagtaatcc aggcatagta accacctaaa
     5881 attgaatgaa gcttgaaaaa cgattgtgaa tctccccaag cgcttatcag tcggcttttt
     5941 tctttcaact tttttcttac atcttgcatt ttcaaatcaa ttgcttcatt aaatacatta
     6001 gccactgtga tttgtgtaag gatattcatc gaaaactcca tcatttcttg cgcttgagct
     6061 agttgcgaga taaaagtctc aggtcctatc acccaaccga ttttcgttgt ttttcctaaa
     6121 accctagata acgaaccgac gtataacaca ttatccggat caatcgttcg tataggaagg
     6181 acttcttctt ggtttagaaa tgaaagatcc gtaaatacat cgtcttcaat aattggaagc
     6241 cgatactgtc gacacaattc tactagcttt tctcgtcgtt tttgactcat cacttttcct
     6301 gtagggtttt gaaaattcgg gttgataagc actgctttca atttattttt atggatcgat
     6361 tctttcagtt tttctaagtc gatcccttct tcatccatcg gtatcccaaa taaacgcgtt
     6421 cctgaagctt tgaaaagagg taatcggtaa aaaaaagaag gtgactctac agctatcccc
     6481 tctccagctg aaagaatcgt ttgtaaaatc aaaaagattg cttgctgacc gccaccagtc
     6541 acaagaagct ggttggggga aaatgccaat tcaaatttac tttccaaata ccgtttgatt
     6601 ttgttacgta acggagtata gcctaaaaga tccatttctt tttcttccgc taagatttct
     6661 tcaagagaat aagaaggaaa ctcaaaattc ggcaaaagct catctggcat ctcgctagcg
     6721 tataaatcaa gaaacgatgt tttttggatc tgctttgctt ctcttatttt ttgctcatac
     6781 cagtccgtct gctcataacg aggagagatc atttgccgcc aatcgattct tggaacagcg
     6841 aatttccccc attcagtctg attaacaaac catccgctgc cacgtttgct cgttagtacc
     6901 ccaagctccc taagctcttc caatgcatgg acaacggtgg aacgattcac accaaaaagt
     6961 tgccctagtt ttcgttctga ttcaagttga cttccaggat tgatccttcc gttttcgatt
     7021 tctctcataa tctgttccat aatttgacga taaatcggtc cttgtttttt ctctactttt
     7081 tcccacataa gcttctcttt tctattgtct attttttctt ttgattttac cgaatttacg
     7141 agaaaaaaga aaaacttttt ttgcaaaaca taagggactg tgacaaaaat
//
LOCUS       DAIGTA010000092         7164 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.098, whole genome shotgun sequence.
ACCESSION   DAIGTA010000092 DAIGTA010000000
VERSION     DAIGTA010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.098"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            238..1629
                     /locus_tag="NOB43_002541"
     CDS             238..1629
                     /locus_tag="NOB43_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI0983367.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAESAFPKEKTYR"
     gene            1667..2497
                     /locus_tag="NOB43_002542"
     CDS             1667..2497
                     /locus_tag="NOB43_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0983368.1"
                     /translation="MENKNISILLSLYDKEKPEYLKEALASIFEQTVMPAEIVLVYDG
                     PINEKLQAVVTYFQQKVPHLFTVVKLEKNQGLGIALATGLEHTKNRLVARMDTDDIME
                     PHRLEKQLEIFQEYPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFN
                     HMTVMFDKNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYAR
                     RGGSKYLLPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN
                     "
     gene            2469..3458
                     /locus_tag="NOB43_002543"
     CDS             2469..3458
                     /locus_tag="NOB43_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0983369.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLRRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNYGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNHPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFLYLINPKTYFILYKKVLKK"
     gene            3572..4567
                     /locus_tag="NOB43_002544"
     CDS             3572..4567
                     /locus_tag="NOB43_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0983370.1"
                     /translation="MHKISVIVPAYNVENYLENCLESISNQTHSNIEIIVVDDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILVFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
     gene            4571..5713
                     /locus_tag="NOB43_002545"
     CDS             4571..5713
                     /locus_tag="NOB43_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HCI0983371.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQFYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSEK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNLMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELLERDIK"
     gene            5710..7137
                     /locus_tag="NOB43_002546"
     CDS             5710..7137
                     /locus_tag="NOB43_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCI0983372.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFLQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIAGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIILFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPLFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTALSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVVLFFIVNLTLTTSAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEVRKIIRK"
BASE COUNT         2559 a          932 c         1260 g         2413 t
ORIGIN      
        1 tatatgaata ttgtaacttg tgaataagga attagcagga gaatactagt tcagcataaa
       61 ggaagtgatg ggacttctga gacaactttc tgttatgcag aaatacacat ataaacagac
      121 aataaacgct tttccccgtt tcttttaatt tcctttacaa tttggttatt cactaggttt
      181 ttaaactttg ctatggtaag atgatagagg cattatttta tggttaggag tgtatatatg
      241 aataaaaatg gggagtggaa tgcggcacgc agaatattca ttattcttat ggatgtactt
      301 gtattaaatg tatcgatcta tcttagtttt ttgctgaaat tccagggaga agtaccagtg
      361 agaaacttag aaacctttca gcattcagca atttttattt ccatcatctt tattgcgttg
      421 aatattttgt taggagctta tgtattctat aaccgaatga tcagtgatat tgtcttcatt
      481 actgttattg gacaagtact aatagcattg gggatcatgg tagttacttt tgctggccga
      541 tggtttgcat ttccgcgtgg cgtcattttg atctcgttta tcctaggtac gatattactt
      601 agtgtttacc ggatagtcgt ttacaaactg tacttaagag tcagtcgtga taagaaagtc
      661 cttatcgtgg gtttggagaa agatgtcgca ccagctatcc aaaattttca atctaagaaa
      721 aacaataaac ataaggttga agcagtggca atcgataatt attacgaaaa tacaaaaaaa
      781 ttgatcgatg atatggatat cgtctatttg gcttctaaaa tcccagaaga tgaaaaaatc
      841 aacatttatc aattagtgac taaaaaagag aagaaattat ttttaaatac gacttttgag
      901 aatctgacaa tgataaatcc gaatattatg aattttgaag atgaaagcat cattgaagct
      961 tctgggttca gaatccaacc agaatacgaa ctattcaagc gtctctttga tatcatcgtt
     1021 tcgcttattt tactgatcct cgcctcacct tttatgctaa tcacagcgat tttggtaaaa
     1081 acaacttcac ctggaccaat catctataaa caagtacgta ttacgaaaaa tcaaaaggaa
     1141 ttttcaatct ataaattccg ttccatgagt gcgacagctg aagcaaaatc aggaccagtc
     1201 ttggctaaaa gtaacgatgc acgtgtgaca ccagtaggta aatttatccg tgctgtacgt
     1261 tttgacgaat tacctcaaat ctttaatgta ttgaaaggcg atatgtcgat tgtcggtcca
     1321 aggccagaaa gaccattttt cgttgatcag ttcaatgaag aaaatcctta ttattactta
     1381 agacacaatg tacgtgcggg aattaccgga tatgcacaag tatacggaaa atatgtatca
     1441 gattataaca gtaaactacg ttttgatttg ttgtatatca aaaagtattc cttactatta
     1501 gatttgaaga ttttacttca aacaatcaaa atcttatttg ataagatgtc ctcacaagga
     1561 ctagatgaag atgaaaatat cagttcatta gcagaaagtg catttccaaa agaaaaaacg
     1621 tatcgttaga ttggaaaaat tttgagcaaa gaagtaggag agaacattgg aaaataaaaa
     1681 tataagtata ctgctttctt tgtatgataa agaaaagccg gaatatttaa aggaagcatt
     1741 agctagtatc tttgagcaaa cggtgatgcc ggcagaaatc gtattggttt atgatggccc
     1801 tataaatgag aagcttcagg cagttgtcac ttatttccag caaaaagttc ctcacttgtt
     1861 tacagttgta aaattagaaa aaaatcaagg attggggatt gctttagcaa ctggattaga
     1921 acatactaaa aatcgcttag tggccagaat ggatacagat gacatcatgg aaccacacag
     1981 attggaaaaa caattagaga tcttccaaga atatccagaa atagcgattg ttgggagtaa
     2041 tattgaagaa tttactggca cacttagcaa tgttatcgga agaaggattg tacctgagta
     2101 taatgatgaa atccgtgtgt tttcgaaaag aagaaaccct tttaatcata tgacagtcat
     2161 gtttgataaa aatgctattt tagaagtggg aaactatcgc ccattaattg gatttgaaga
     2221 ttattatttg tgggtaagac tattgaaggc gggatataaa ggatataata tccaagagat
     2281 tctagtacat gctagagcag gtgctgacat gtatgctaga cgtggaggaa gtaaatatct
     2341 tttaccagga attaaaggcc gatatcgcgt atggaaagat ggtctaggat cactaaaaga
     2401 ttttctgata gttatttgcg gacatcttgt aattagttta ttaccgaata aaattagggg
     2461 aaaagtatat gaatcaaaac ttagaaaaac aaactaaact ttctataatc ataccttttt
     2521 acaatgcaaa gaatacttta agaagagctg tagacagcgt cttaacgcaa ggttatccca
     2581 atattgaaat cttgttaatt gatgatggat ctacagatgg tagtagtgac attggtgacg
     2641 aaattgctaa tctagagagt aaagtagcat gttatcactt ggaaaacgct ggtccatcag
     2701 ttgctaggaa ctatgggata aaagaagcaa ctggaaattt ggtaggattt ttagatagtg
     2761 acgattattt tttacctgat tgttttaata atgttttgaa agactaccat aggaatcacc
     2821 ccgatatcat tgcttttgga ttaagtaaag gaaaaaatat agaaaatgca aatttatttg
     2881 ttcccgaaaa gaagattggt tgttcaagtg aagaagcaat tgagcaaatg tttagaagta
     2941 aggcagtgga cttttacgta tggaataaat tttttaaaag ggaattattc aatcatatag
     3001 tttttccaga aaataaatta tatgaggata tggttcctat gtatgaagct tttagggcgg
     3061 ctagtaaaat tgatattttg ccattttcag gtatttttta ttatcaaaat aacgatagca
     3121 tcgtttatca gtcttttaat tcaaaacagt atgataatat tttgcagaga aaaatattag
     3181 ttgatgaagt aaagaaagat tatcctcgac ttattaattt ggccaatgct cggttagtag
     3241 acggatatct ttcaacaggg tttaaaatta ctggcaaaaa tcaaaatcag aaagaaaaac
     3301 aaaaatatta taatcagtct aaaagagaaa taaaaagtat atattcaaaa ataagaagta
     3361 acaatgagat atcaattgct aaaaaattag ctttattttt atacttaatt aatcctaaaa
     3421 cttattttat tttatataaa aaagttctaa aaaaataaag tttttttcga tatgttattt
     3481 tttatgttta ttaacttcgg aagactaaaa ttgttactgg taatgataca tttgtaaaaa
     3541 taaaaaagat gatttttagg aagtgaagag agtgcataaa attagtgtta tagtacccgc
     3601 atataacgta gaaaactatt tagaaaactg cttagaatct atttccaatc agacacattc
     3661 aaatattgaa ataatagtag tcgatgatgg ttccccggat cgaagtgggg aaattgcaga
     3721 agaatataaa aagaaagata tgcgattaaa agtgatacat caagtgaatg gtggtttaag
     3781 tgcggctagg aattctggtc ttgattctgc aacaggagat tttgtgtgct ttattgacag
     3841 cgatgattgg atagaaccag actatcttga gttactatat tttggtacgc aaacttatgg
     3901 agcagatatc tcggtgctaa aaataaaaaa gatttcaagt ttagaacaac taaaagaaca
     3961 tacaattgct gagagaaaat gggaaatatt tgatagagaa caagcaatga aaaacttatt
     4021 tataaataat aaaattggct attctgcaaa taataaatta ttcaatagaa atttatttga
     4081 taatataaga ttcccactgg gtaaattaat ggaagataag gctactactt atttgttgat
     4141 cgatcattcc gaaaaagttg ctgtcaattc atctgctaaa tatcactatt accaaagccc
     4201 taaaagtata ctgagaggaa gcttcaatcc tagaattttt gattcttttg aagtccatga
     4261 agatatacta gtattcatag ataagtttta tccggaatta tcaattaatg ttagaactcg
     4321 ctatgtctat gaagcaataa ggatgatgat gacaatgatt aaaaataact ataccaataa
     4381 agaagattat ttacgttcta taaatatttt acaacgcttt gaaaaagaag tgaaaattga
     4441 tcccgacttt tcaccaaaat taaaaaaatt agtaaagttt ttattaataa ataaaaactt
     4501 gccttactat atgtcaagta gtaagatagc aagtaaattt ttgattaaga tagaatctgt
     4561 gaggtaagag atgaagaata taaaaaaatt tttttcaagg aatattttcc cggtttttat
     4621 taaaatatta cctattcaaa aaaatttaat tgtattttca agttttggcg ggcgtaatta
     4681 ttctggaaat ccaagagtta tttcagagaa aattcatgaa aaaaaattga attacagaat
     4741 tatttggtta atcaaaaaag aagcgattat aactgattta ccagattata ttaaaagaat
     4801 tgattccgat tcttttttag ctgcctttta tttgtataca gctaagtatt ggatagacga
     4861 tagtcggaaa acgattaagt atgcaaaaag gaaaaaacaa ttttattttc aaacatggca
     4921 cggtacgcct ttaaaaaaaa ttgaatttga tgcaaaagat aagttaccta aacgttacct
     4981 aagctatgcg aaaaaagata gtgagtcaat tacatattta ttatctggta atcgctatag
     5041 ttctgagaag tatgtttcag cattcaatat cgttccttct aaaatattag aagtaggaac
     5101 tcctagaaac gatgaattag cctctagtaa agagcaagtg tttgacttga aaaagaaaca
     5161 aatcaatgtc ttatttgctc caacttttcg aaataatatt gaggacaacg gaattacgca
     5221 actagaatgg ttaggtgtgg ataacttacg tgaatttttt aaaaagcaac aacaagaatt
     5281 aaatttaatg actaaatttc atcctaatgt tcatagtaaa ttagcaactg attctaaaag
     5341 tatagaatat atgaaaaaac atcaaattac tttaattaat gatgggattc ctcttgaaat
     5401 gctttttgaa gagatagatg ttttaatcac agattattca tctatttttt tcgattttgc
     5461 gctaacaaaa aaaccaatta ttctttttaa ctatgatgaa aaagaatata gcttagaaag
     5521 aggtttttat atacagttaa gtgagttacc aattataagc gtacaagata gttatggcct
     5581 tgttgatgtt tttaaaaacc aacaagaaaa gcttttgaaa agttctcaag agttacttga
     5641 ttatattgga aattatgaaa caggggcaag tacagaaaag gttcttgagt tgttagagag
     5701 ggatataaag tgaaaaaaac agtaaaagat atattttata atgcgatata tcaagtcttt
     5761 ttgattgttt tgcccttact tactatacct atacttagtc gtagaatagg ttcaactggt
     5821 ttagggattt atgggtatgt tttctcaata tcacaatttt taatgactgt cattgctgtg
     5881 ggaatgaatc cttttcgtat tcgaaatatc gctaaatcaa ggaaagataa aaaagcacta
     5941 tctttacaat tctggaatat ttactttctt caatttttaa taggcttgag tgtttccttt
     6001 ctctatatag cctatattta tttttttgat gtaaagtata aaaatttata cttaattcaa
     6061 ttgatattta ttgcagggct aacattagat atttcttggt tttttcaagg aattgaagaa
     6121 ttttcgaaag tggttattag aaatacagtt atcaaattat catcggtatt gttaataatc
     6181 ctttttgttt caactaaaga tgatttgtgg atttatgtgt tcattacttc aattactaac
     6241 tttttaggaa gtttagtttt ctggttgagt atccacggaa aagtaggtaa accactcttt
     6301 aactctaatg tttttaaaca gttgtggaaa ccagctttta ttattttgac tcctcagttg
     6361 tttatgcaag tgtacacaac tttagacaaa acgatagttg ggtattttgt ggatccaaca
     6421 gcattatctt attatgatca gtctcaaaaa attgctcgta ttatattggc agtcttaaca
     6481 tcaattacta ttgttatgtt gcctaaaata tctaaagcac aggcagaggg aaaatcagaa
     6541 aatattttag tttacacaaa aaaatctttt gattacacga ttattattgc attaattctt
     6601 tttagtgtgg tgtttatcaa tacaaaagaa tttgttccat ggttttttgg ggagaatttc
     6661 aaaccgatga caataaacat gcttatttct tgtctaatta tagttgttag tccaattggt
     6721 ggagtttttg ctaaccaatt tgcaattgct atagaaaaag ataaggagta tgcttatcca
     6781 atgatcattg gtgcgattgt aagtattatt ggaaatgtag cttttgtgcc tacttatggc
     6841 gctgtagcgg ctacaatcgt actcgtggta gtagaattat tagtcttttt ctttagagta
     6901 ttttttgtac gaaaagaaat aaaaatatcc tatttctttg ggaagaacgt tgtcttattt
     6961 tttatagtca atcttacttt gactacttcg gcctattact ttcttccaca attattctct
     7021 tcttcatttt tagatatggc aattaaatca ataatgattt tcattattta tcttccgttt
     7081 gtttattttc tttttccaga tatacgaaat gaagtaagaa agattattcg aaaataaaat
     7141 aatgttgtaa aaaagtagtt cttt
//
LOCUS       DAIGTA010000093         6758 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.099, whole genome shotgun sequence.
ACCESSION   DAIGTA010000093 DAIGTA010000000
VERSION     DAIGTA010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.099"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(193..1104)
                     /locus_tag="NOB43_002547"
     CDS             complement(193..1104)
                     /locus_tag="NOB43_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI0983373.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(1561..1989)
                     /locus_tag="NOB43_002548"
     CDS             complement(1561..1989)
                     /locus_tag="NOB43_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983374.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(2017..2655)
                     /locus_tag="NOB43_002549"
     CDS             complement(2017..2655)
                     /locus_tag="NOB43_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983375.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(2659..4641)
                     /locus_tag="NOB43_002550"
     CDS             complement(2659..4641)
                     /locus_tag="NOB43_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HCI0983376.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4821..5486
                     /locus_tag="NOB43_002551"
     CDS             4821..5486
                     /locus_tag="NOB43_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983377.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT         2178 a         1231 c         1021 g         2328 t
ORIGIN      
        1 tgatattgtt ttctttattt aagattatac agaaaaatat ctagggtcgc tggattctaa
       61 gtaaaaaaaa tttttaaaat aaaaagaact aaatcaagta gtaattaaac tactgttgat
      121 ttagttctaa taaaaagatt tagatgaaca gttttattga tttaaatagt tcatattttt
      181 tatttatacc gcttatttac tacttgctgt actagaatct gaagtgaatg tactcaaaac
      241 attttcaaag tctttgtctt tgatttttac attagcgtct ttcaatactt cgccaattac
      301 tttattctgg aaggtactgt cacttaattt tgtgtctgtt gcaatttctt tcaattcttt
      361 tttgtattta tccatgtcgt tgcctttgtt ttggtttttc accattttaa ccacataata
      421 ttccgtagta taagttgaag cattggtaga agtgatcaca tcagaaactt gaccatcttt
      481 caacttaaag gctgcttctt tgacttctgc cggaaccgtt gtagtagtgg aatcaaattt
      541 cacttttccg ccatcttctt ttgtcgtagt atcagttgac ttgtctttgg ctaatttaga
      601 gaaatcgtct cccttatcag cagctttctt cacatctttt gcatcatctt cacttgctac
      661 ttggataatt tgagcttcca cttctggatg gaaagattcc caagccgttt ttaaatcttc
      721 atcggtcaat ttgatatgtt tctttagacc ttcttgaaag gctagacttt gtttgatact
      781 gtctttgaat gtttgttctg tgtaacctgc agatttcaat tgtgaatcaa atgaatcacc
      841 caattgtttc tttgtttgat catattgaga atcgatttct ttggttgata cgtcatctcc
      901 atatttatct tcaaatactt gataaacgat caactgttgc acagcggaat ctgctccttg
      961 catttttttc aagctatcca ttacttcttg ttcgctgatt gtaccgcctt tataactaac
     1021 ggctgttttt tcaccggcat tcgtacagcc tgacaataag ccagtgccta gtacgatggc
     1081 aagtgctaaa aatctttttt tcatttatca attctcctac ttttcgtttt ttgcgaattg
     1141 ctaaaaacaa aggtgttcaa gatgaaaatc atcaagaaca cctttactaa tctgctcgat
     1201 acgtcctgaa tagatataag gctacacaat ccagaaagtt cgctcagcag aataaatgtc
     1261 aagtagcaca tcacacctta atatactact tcttttgtta ccgtttttca agtctatctt
     1321 gcgttccgta tttaacgtaa ctaattctta gaacaaatgt tatcgatttt gtttttcttc
     1381 ttccgctgct gggatattca aatcagacac ttttatgttc gattttccag acattttttt
     1441 gttgttttta ttatgatata tttttataca actaaaaatg aatatattaa aactaccaaa
     1501 aataactttt aacgctgttt cattatatgt tttttctatt ttatataaac ttttggatac
     1561 ttaataccaa ccggttggat tgtaccaaca tgagaatgtg tcagttctat ttcctgtcgc
     1621 acttgcatag gcccatactc cttttgttgc atttgctgat cgaatagagt ttccaacttt
     1681 cgcttttgca ccgtgacgat tatagacacg actatagtgg ttagaatgac ctgtttttct
     1741 cgtacaagtt gtatcactat aataaaccca tcttccagag ctatgattaa ttgctgttct
     1801 agaaatttcc cggtctactg gtaaatttga cttaataata ttacctttag catcaaaatg
     1861 aatctctcct ggctttaaag atttgtaata gatttcaccg tgaactgaat ttgcttccac
     1921 ttcagatgac atagcgtttc ctccaacaaa acctatccct agtgcacaaa taataactgc
     1981 ttttttcata aaacgacatc ctttcctttt tgatttttaa agcatgatct tcttgtttcc
     2041 tattttggtc agatatggat catgcgtgac tacgataact aacgtacctt gggaagcttg
     2101 ttgcgataag atttcaacta ctttatcctt atttctttta tccaatgacc cagtcggttc
     2161 atcggctaaa atgattttgc tattcttcaa taagactctc gcacaggcga ttctttgctt
     2221 ctcaccacca gataatgtgt agataggcgt acttagcttc ttgtttatat ttactttttt
     2281 caatgcctca tactttgctg ttcgcttatc tgaaacattt aaattcgaaa acttcaatcc
     2341 aatatctaaa ttaaaatcga ttgtttcata ttcaatcaac ccaaaatctt gaaaaagaaa
     2401 agatatggta tttcttttta tcaagcgctt ctctctccca gttaattgtt tcgtctcttg
     2461 atcgaacaaa tagaattgtc ctgaactgaa ctgatcattc aatcctaata tattcaataa
     2521 cgtactttta cctgctccac tttctccaac aacagtcaca agatccccag catccgcagt
     2581 gaaacgatcc aaatgaagaa tcgttttgtt tcgaatgatt tttttcgcac cttttatcac
     2641 tatcaacggc tccaattgtt aacctccatt catcagcaat aactgacttt tcttttctgt
     2701 agacaaaata aaaacaactg aaagaataaa atcaatgaag ctaaagaaaa aaatattaaa
     2761 aagatattta ggctctcttt ctataagaaa aaggaagatt acacttgtcg ttccccattt
     2821 gatgaggttc atcatgaaga aatctttata cgtttcaaag agcgaataac cacttgaacg
     2881 aaagatagcg attttccgac aattgtagac aaaatatatg cataacatga catagctcaa
     2941 caagaagaaa gaaaagaaag tgagtaaaaa tatctgtatc aagtaatgaa atgatctgct
     3001 taacactttg acagctatct cttcagtctg agtatacgga aatgataact gcaagttatc
     3061 acgtaactga ctttcttcaa tcagctcaaa taacctttct ttcgacaaag agcctatctt
     3121 gatctttaac ggtggataga tttctccgct gagaatattt ctttccaaat acatactgtt
     3181 tttcaatgtc agtatttcaa caaccggata atgttcgatc caggggatag aaggaataaa
     3241 tgtataaatg ggttgattgt tttttataaa tagaaatttc ggttcttttt cactgatttc
     3301 ttgataatat tctgttattt gcgccaggtc attttttaaa tctgtatgtc tatatcgttc
     3361 agggatcaat ataacagggt gcgtttcttt ttcggttatt tggatcaacc ttccagagac
     3421 atcaatcaaa ggaaatttct taagataatt cagatttatt tttatccctc tgccaaactg
     3481 ttcattttct tcattcaagt aatctgatac attgactaat atacttccgt ttttattcaa
     3541 agtttcatat aattcctgat ctgctgctga tgcaaaacga ttggaataaa taaaatccac
     3601 gtggtttttc ccgatggtta ctggataaaa tacatgatag tcctcaccag cgatttcttt
     3661 tggtggttca tgggaaacag ctaactgtga agaagaaaaa acgatagttg ctaattcgac
     3721 attggcaacg gtcaaaagaa gagaaaacaa caatccaaat gtaaaaagaa tgtattggat
     3781 atagttgaac gcttctctta acgaagcgat tttttcaact aataaaagag aaatcaaaga
     3841 gataccatat attccgctga acaagaaaac gtacatctgg aacaaataaa gaaattgctc
     3901 cttataatac ataaaaataa aaccaccaat gattcctgca attatgaatg taataatgat
     3961 tttctttttc cccaataaac accacaatac ttgatgtaat gaaaagtcat tattcaacaa
     4021 taaactgatt tctttattca tcaataagaa aaaggatgat aacaaaagga ataaaagaat
     4081 caatccaata gttaaataca ctcgataatt atatacgtct gtatttgaaa taaccgaata
     4141 cgaatagcta ttttcaaagt cttcaaaaat attagtggca taatcagtgt gaaatgcttg
     4201 attgaatcga tcagtgaata gtgaaatgaa ccgttcatag gcttcttttt ctctcgtcat
     4261 caagaaaaat tcaccttcaa aatcttttat tttgatcgat tcttcaatgg acgttacgcg
     4321 aaaggaggta ttagaatagg gtaccttctc gtgagaagat ttgacatccc cttgataata
     4381 caatgtcatt tcaagctttg gctgtatctt gaagttccaa gatgtatcta cttcattgga
     4441 ttcatttact gtttttttca tataagaaag ctcagtttct gatgagacat tttcaaatac
     4501 catgattagc tgctcatatt cttcttgccc aataaaatgt tgtggcaatc gaatcggagt
     4561 ataagtatct gtttgatgga aaaattcatt tgtccgatag agtacctgtt tatttatact
     4621 aaccaaggca aaaccactca tgataccggt cactatgatt gtgagtaaaa ctgtgaactt
     4681 ttttttgatt atcaccactc tcccttactt aaatgattct ttgataaaat cataccgttt
     4741 ttcatcaaaa aaacgtatct atcaagtgta taggtcatgt agaataaatc tatatactgt
     4801 agaatcgaaa ggagaagaag atgaacaccg gagaaaaaat acgaacttac cgcagaaatt
     4861 gtaagcttac gcaaaaagaa ttaggcgaaa aaattggtgt ttccgataaa acgatttcta
     4921 gttgggaaaa ttctcgtaca atgccagacc ttgaaatgct gtcactttta catcatactt
     4981 taggtctgcc gattgatttt ccttctattg aatcagctac cgaatcaata gaaccaacat
     5041 tgccagatga acctcttgtt aacaagaaat cttattcatc aaaacaaccc ttctcactca
     5101 aaaagacact atctttcttt ctgctcgtct tttgtttggt ctatcttttt cttatcaatt
     5161 atcaatacaa aaatgaaacg atcgatcgat tcaatccttt tttgaaacca caaatcggct
     5221 ataccacact ccctgtagga tacgtggaca attccatcga acgttgggta tgtaatgata
     5281 tctttggcca tggtacatgg ctgtcttttc acgctggaga ggtagaaaaa gagaaaaacc
     5341 atgctgtaat caaacacaaa ggaaaacacg tcatgaacgt tcgcctgctc acttgggaag
     5401 ccattccctc agattaccaa gaaatcctca gccaagacta tgacgacgcc ttaaaaagaa
     5461 gccctcagga gccagatagg cattaagtag gagatgaacg tagagataga aaaaatcaat
     5521 gcacatgatc ttatccaaaa aacaggggta caaattaatt gaaaaagcct tgagatgaaa
     5581 gttcctaaat aaaaaagttc agaatgatag gtatttctgg cttatagtat aatatttacg
     5641 ccacagcctc ccaatgattc tttttggaat cataatcaag gatggacatt cacaaaaata
     5701 ttttgctcat tcgatccgaa tagattaacg accaatctag taagtaatat agattggtac
     5761 gtagtcaagc tgcacataat ttagatcaat tttagttctt ttttatattt ctatgatctg
     5821 ctcatttact tttatatgat ggcttacagt aacataaata aatatgataa tcgctggtag
     5881 tttatccaag agtactcaat aaaatacaaa atggattgtt caagcgccta tcataatgat
     5941 aaaatgaaac aaataaacga tacaaggagg aagagacttt gagtaatggc agaacaattt
     6001 tttcattgta aaaattgttc agttgttaat ctatgggatt tcggtagcat gggcattttt
     6061 ttatagagga atcacaccaa cctggccgtt ttatctcttg ttagtgggaa tattagtagg
     6121 aaattttgcc cctcttcact atcgtacgaa cttttttcca actgattctg gcctttttct
     6181 taaaacaaag acgcgaaaat tagaaaacat tattgaaatg acaattacct gtataatcat
     6241 tttcttagtt atattcctaa acgtcttcta ataagaatct cttaaaatta gcttgttaca
     6301 gttagttacc tagtttatat aacacagtta tcttatcttc cttatcaaca tcttttgcca
     6361 actctttgtc ttaaattcga aacatataag cagagctacg aacaccaaga ctgtttcggc
     6421 tctgtttttt gcatcaaatt cactcttata tagctgataa tctcggctct ttaaaagaaa
     6481 ttattttcgc ttcattttat tataaaaagg ctaggaacct tgatgttatc aggttcctag
     6541 cctttattta agtattaccc cacagaccct tccatataga tttttaaatt acacactagt
     6601 ttaaactaaa acaaacaagg aaacacttac catttaatca taaaattagc tcatatgaat
     6661 atattagaat gtaaaataga ctggtcaaaa tctggtcaaa aaagaggact aatacaggta
     6721 gtcctcagac tgtagacaaa gtccatttta tggatgat
//
LOCUS       DAIGTA010000094         6381 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.100, whole genome shotgun sequence.
ACCESSION   DAIGTA010000094 DAIGTA010000000
VERSION     DAIGTA010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.100"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            152..2095
                     /locus_tag="NOB43_002552"
     CDS             152..2095
                     /locus_tag="NOB43_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0983378.1"
                     /translation="MLSKRESQLIELLLEEENFQPASFFSEKLNVSNKTIYQDIQKLG
                     QFLNRFELKIEKKPRMGIYLIGTSTKKNDAKIFITSKEAMSTKVKYSSNYRRVYLFAN
                     LIFKTDKKRYEYFEKKFFVSIATLRKDYEEIIKYCRLAGIRITSNHVIDTQKTPEELI
                     QRTFVNYFEKNIGVGNEKCQYHFVFDQAMVKFVDDFVKNFYQQSKQQPTNYIVHSLKL
                     SLLTLIGRVKHGYHSQTNKNPLFVEIKKMELYMVALDFSNGVKDELNCSFTINDLYFI
                     CSLFMGHGVRPFVNLATHSQQIMETTKQFIQDMSTLVEKDLGQDSQLLQSLFAHIEPM
                     VYRLQMGITIKNPLKEDIIRQYSTMYTLATYCIPKLEKAMGIRVTDDEITFLTIHFQL
                     AFEKIVNTKHVFLICPTGLGTSQLLFQRIRHSSPSTVVYEVIDVQKLQDYNLDSVDLI
                     ISTVKLENEYQTPVIYVRPLPTKEEIALINRHLLTLNQQDNTFLPSIAPDKTILKKYL
                     KDGWMFLNQDFDSRESVLSFITEKYKEEQLVKDNFLEVVLQREKLGATGLSSGVAIPH
                     ANPKYVVKTKISIITLKNKITWGDVDIRVVLFLAIAEEDMIQVKNMIALLYDVFVSPE
                     RIKSIASKETRNEIINEIIGKRK"
     gene            2097..2558
                     /locus_tag="NOB43_002553"
     CDS             2097..2558
                     /locus_tag="NOB43_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0983379.1"
                     /translation="MTSYFGKKIALFQSEVKSQKEALSIIATCLYQTGLVKDSFAENV
                     LKREEVFPTGLLINDVGIAIPHTDAEHVNDSQIAFMSLKTPVTFYEMGTADKEISVSL
                     IFMLALKEPHAQLEMLQKLITMFQKKEVVQKLRAVNNTEEYYQIIEKEGFV"
     gene            2582..3928
                     /locus_tag="NOB43_002554"
     CDS             2582..3928
                     /locus_tag="NOB43_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI0983380.1"
                     /translation="MLDLLQKFVDLGSIVVLPILIFVFGLILGTKPSKAFISALTVGV
                     GFVGLNLVIDLLTNSLGPAAQAMVERFGLNLTTIDVGWPAAAAISYGTVLGSLAIPVA
                     IVVNVLLIIVGLTKTLNVDIWNIWHAAFVASLVYAVTNDFAMGMLATVIYTMMILLFG
                     DILGPIINKFYGFPNITFPHGTSAPGFVFALPLNWLFDRIPGLKDWHADPETIQKRFG
                     IFGDSTVMGFLIGLVMGILAGYDVAGIGQLAVKTGAVMVLMPKMVALLMEGLTPISES
                     ANSFVQKRFPGRELYIGMDAALSVGHPAVLSSSLILVPITILLAVILPGNTTLPFGDL
                     ATIPFLICLMAAVFGGNIIRTILGGTIYMVTILYITSWVAPFLTKAAQGANFDLQGHS
                     SVTAMAEGGLWTTLLYVGGAKLFGYFALVGIGLIITGLLFYVNRILPKRAAKQTEA"
     gene            3951..4235
                     /locus_tag="NOB43_002555"
     CDS             3951..4235
                     /locus_tag="NOB43_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0983381.1"
                     /translation="MKKLLIMCGTGVATSTVVTGKVKEWLKSKGLENEVKLYQSKVAD
                     EIGKIDDYDIVVSTTVVPDNIKDKVIMGLPLLTGIGIDGLFDEIEAKIKA"
     gene            4262..5089
                     /locus_tag="NOB43_002556"
     CDS             4262..5089
                     /locus_tag="NOB43_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HCI0983382.1"
                     /translation="MLVTTKEMFEKAQKENYAIPAANFFDLDSARTFVEVAEKMQKPL
                     ILAFAQAHIEECPLEEAALIATYLAKKASVPVALHLDHGQDEEIIKQAIELGFTSVMI
                     DASQDEIETNIRRSKAIAEYAHERGVVVEAEIGHVGTGNSYEFKETTDTIYTEVEEAA
                     RFAKETGVDSLAVSIGTAHGQYKGTPKISFERLEEIKNEVSIPLVLHGGSSSGDENLH
                     KCAVSGINKINIFTDFITAAMDVINEEKPEDYFTLKRLANQAIADTLSHYYEVFATK"
     gene            5102..5797
                     /locus_tag="NOB43_002557"
     CDS             5102..5797
                     /locus_tag="NOB43_002557"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCI0983383.1"
                     /translation="MRTVRKPFFVVNPKSYLYGEQALKLAKTADQLAAAYDIDIIFTC
                     QHVDVRLIKEQTTQLIVSVQHIDGIVPGRGMGHVLPEGVVAAGAEATFLNHAERPLSV
                     SELCDAVKRAKELGLLTIVCANSLEEAKLVASLKPDVMVCEPTELIGTGQASDISYMI
                     QTNEAVRKMDPEIFVLQAAGISTVADVRKALDSGADATGGTSGIVCAKDPVDTLKAMI
                     EEVSKWKKEQSTK"
     gene            5794..6309
                     /locus_tag="NOB43_002558"
     CDS             5794..6309
                     /locus_tag="NOB43_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016380999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HCI0983384.1"
                     /translation="MITYTEQLVLTSNGQRVTYHNITEQVKEIVAKSGIKNGICLVQS
                     PHTTCSVIFEEFMHDLDFNGDEFLQVDLNRILDRIIPRELTENTDYRYPGPKHLDFLL
                     SLDDPDYAGDAGTILNGDAHIRASFFGASENFIVKEEILMTGTVGSIYFIDFDQNRVR
                     NRKCHILVMGE"
BASE COUNT         2114 a          968 c         1362 g         1937 t
ORIGIN      
        1 ttaaaaaaat tgtcgtgagt tttactgaca tcaaaaagta tagggtcata ataatctgtt
       61 ccacattaat gtggaacaga ttacgtattg atctttagtg agaaaaactc tatgatatag
      121 acaaggaaaa cgttttctga ggtgatgatg gatgttatca aagcgcgaga gtcagttaat
      181 tgaattactt ttagaggagg agaattttca accagcaagt ttctttagtg aaaaactcaa
      241 tgtttcgaat aaaacaattt atcaagatat tcagaagctg ggacagttcc tgaatcgttt
      301 tgagttaaaa attgaaaaaa aacctcgcat ggggatttac ttaattggaa cgtcaactaa
      361 aaaaaatgat gccaaaatat ttatcactag taaagaagct atgtcaacaa aggtaaagta
      421 tagttcaaat tatcgtagag tgtacttatt cgccaatcta atttttaaaa cggataaaaa
      481 aagatatgag tattttgaaa aaaagttttt tgtcagtatt gcaactttgc gtaaggacta
      541 tgaagaaatc atcaaatatt gtcggttagc tgggattagg attacttcaa atcatgtaat
      601 agacacacaa aaaacacctg aagagttgat ccagcggaca tttgttaatt attttgaaaa
      661 aaacatcggt gtagggaatg aaaagtgtca atatcacttt gtttttgatc aagcgatggt
      721 taagtttgtg gatgattttg taaaaaattt ttaccaacag tctaagcagc aaccaacaaa
      781 ttatattgtc cattcactca aactttcgtt gttgacgttg attggtcgag taaagcatgg
      841 ctaccattca caaacaaata aaaatccttt gtttgtcgaa ataaagaaaa tggaattata
      901 tatggtggca ctagattttt caaatggggt caaagatgaa ttgaattgtt cctttacgat
      961 aaatgatctt tactttattt gttcgttgtt tatgggacat ggagtgagac cgtttgtgaa
     1021 tctggcaacc catagtcaac aaatcatgga gaccaccaaa caattcattc aagatatgtc
     1081 gacactggtt gagaaggatt tggggcaaga tagtcagctg cttcaatctc tatttgccca
     1141 tattgagcca atggtttatc ggttgcaaat ggggattacc attaaaaatc ctttaaaaga
     1201 ggatatcatt cggcaataca gcacaatgta tacgctagca acttactgta ttccaaaatt
     1261 ggaaaaagca atggggatca gagtaacgga tgatgaaatt acttttttga ctattcattt
     1321 tcagttagct tttgaaaaaa ttgtgaatac gaagcatgtt tttcttattt gtccaacggg
     1381 gttgggaact tcgcaattat tatttcagcg tattcgtcat agttctccta gtaccgtagt
     1441 ctatgaagtg attgatgttc aaaagttgca ggattacaac ttagatagtg tcgatttgat
     1501 tatttcaaca gtcaaattag aaaatgagta tcaaacgccg gttatttatg ttcgaccatt
     1561 accaacgaaa gaagaaattg cattgattaa tcgtcatctt cttaccttga atcaacaaga
     1621 caatacattt ttaccatcca ttgcaccgga taaaacgatt ttaaagaaat atttgaagga
     1681 tggttggatg tttttgaatc aagattttga tagtagagaa tctgtacttt ctttcatcac
     1741 tgagaaatat aaagaagaac aattagtaaa ggataatttt cttgaggttg tacttcaaag
     1801 agaaaaacta ggagctaccg gactttcatc aggcgtagcc atcccacatg caaatcctaa
     1861 atatgtagtc aaaacaaaaa tttctattat cactctaaaa aacaaaatta cttggggaga
     1921 tgtggatata agggttgttt tattcttagc gattgcagaa gaagatatga ttcaagtgaa
     1981 aaatatgatt gcactacttt atgatgtctt tgtctcacct gagagaataa aaagtattgc
     2041 aagtaaagaa acaaggaatg agattattaa cgaaattata ggaaagagga agtaagatga
     2101 cgagttattt tggaaagaaa attgcattat ttcaatctga ggtaaagagt cagaaggaag
     2161 ctttatcaat tattgcaact tgtctatatc aaacaggttt agtgaaggat tcgtttgcag
     2221 agaatgtact gaaaagagaa gaagtgtttc ctactggctt attaatcaat gatgttggga
     2281 ttgctatacc acatacggat gcagaacacg tgaatgattc tcaaattgca tttatgtcat
     2341 tgaaaacacc agtaactttt tatgaaatgg gaactgcaga taaggaaatt tcagttagct
     2401 tgatcttcat gttggcgttg aaagaaccac atgcacagtt agaaatgtta cagaagttaa
     2461 ttacgatgtt tcaaaaaaaa gaggtggttc aaaagcttcg agctgtaaat aatactgagg
     2521 agtattatca aattattgaa aaagaaggat tcgtttaata accattttga gggggagcat
     2581 tatgttagat ttattacaaa aatttgttga tctcggatca atcgttgtat tgccaatctt
     2641 aatttttgtt tttggtttga ttttaggaac aaaaccgagt aaggctttta tttcagcatt
     2701 aacggttggt gttggatttg tcgggttgaa tttagttatc gatttattga ccaatagctt
     2761 aggaccagca gcacaagcga tggttgaacg ttttggacta aacttaacaa ccattgacgt
     2821 tggttggccg gcagcagctg cgatttctta tggaaccgtt ttaggtagtt tggcgattcc
     2881 agtagctatc gtagtcaatg tgttattaat tattgttggc ttaacaaaaa cactgaatgt
     2941 tgatatttgg aatatctggc atgcagcatt tgttgcttca cttgtctacg cagtaacgaa
     3001 tgactttgca atgggcatgt tggcaacggt tatttataca atgatgattt tattgtttgg
     3061 cgatatttta ggaccaatca tcaataaatt ctatggattt ccaaatatta ccttcccaca
     3121 cggaacatca gcacctgggt ttgtttttgc cttaccttta aattggttat tcgataggat
     3181 tccaggattg aaagattggc atgcagatcc agagacgatt caaaaacggt ttggcatctt
     3241 tggtgattca acagtcatgg gctttttaat tggtttggtt atgggaattt tagctggcta
     3301 tgatgttgcg ggaatcggtc aattagcggt gaaaactggt gctgtaatgg tcttaatgcc
     3361 taaaatggtg gcacttttaa tggaaggctt aacacctatt tcagaatcag caaattcatt
     3421 tgttcaaaaa cgtttcccag gaagagaatt atatatcgga atggatgccg cattgtcagt
     3481 aggacaccca gctgtattgt cttcttcgtt aatcttagtc ccaatcacga ttttattagc
     3541 agtgatttta ccaggtaaca caaccttgcc tttcggtgat ttggcaacta ttccattctt
     3601 aatttgtttg atggcagctg tctttggtgg aaacattatt cgaacaatct taggtgggac
     3661 gatctacatg gtcaccattt tatacatcac ttcatgggtg gcaccatttt taacaaaagc
     3721 agcacaaggg gcaaactttg atttacaagg acattcatca gtaactgcga tggcagaagg
     3781 tggactgtgg acaacacttc tatacgtggg tggtgcaaaa ctatttggtt actttgccct
     3841 agtcggaatt ggtctgatta ttacaggctt actattctac gtgaatcgca ttttacctaa
     3901 aagagcagct aaacaaactg aagcttaata caaaatagga gagatgacag atgaaaaaat
     3961 tattaattat gtgcggaaca ggtgtggcta cttcaacagt ggtaacagga aaagtaaaag
     4021 aatggttgaa atcaaaagga ctcgaaaatg aagtgaaact atatcaatca aaagttgctg
     4081 atgagattgg caaaattgat gactacgata ttgtggtcag tacgaccgtg gttcctgaca
     4141 acattaaaga taaagtaatt atggggcttc ctttattaac cggaattggc attgatgggt
     4201 tgtttgacga aattgaagcg aagattaaag cctaaaaaat acttgaaaag aaggtaatca
     4261 aatgttagtt acaacgaaag agatgtttga aaaagcgcaa aaagaaaact atgcgattcc
     4321 ggcagcaaac ttttttgatt tagattctgc aagaaccttt gtagaggttg cagaaaaaat
     4381 gcaaaagcca ttaattttag cctttgcaca agcgcatatt gaagaatgtc ctcttgaaga
     4441 ggcagcgtta attgcaacat atttagccaa aaaagcaagt gttccagtag cacttcattt
     4501 ggatcatgga caagatgagg aaatcatcaa gcaagcaatc gagcttgggt tcacttctgt
     4561 gatgatagat gcttcgcagg atgagattga aacaaatatt cgtcgttcaa aggcgattgc
     4621 ggaatatgct catgaaagag gcgttgtggt agaggctgag attggacacg tgggaacggg
     4681 aaatagttat gaatttaagg aaaccacgga caccatttat accgaagtgg aggaagcagc
     4741 acgttttgcg aaagaaaccg gcgtcgattc attggcagtt tcgataggta cggctcatgg
     4801 gcaatacaaa ggaacaccga aaatcagctt tgagcggttg gaagaaatta aaaatgaagt
     4861 ttcaattcca ttagtgttgc atgggggctc atcatctggt gatgaaaatc tccacaaatg
     4921 tgctgtttca gggatcaata aaattaatat ctttactgat tttatcacag cagcaatgga
     4981 tgtaattaac gaagaaaaac cagaggatta ttttacactt aaacgattag cgaaccaagc
     5041 gattgcggat acgttatcgc attattacga agtatttgca acaaaataga ggagggttct
     5101 catgagaaca gtaagaaaac cattttttgt ggttaatcct aaatcttatt tgtatggtga
     5161 acaggcattg aaactagcaa aaacagcgga tcaattagct gcagcatacg acatcgatat
     5221 catttttact tgtcaacatg ttgatgttcg gctaattaaa gaacagacaa cgcagttgat
     5281 tgtgagtgtt caacatatcg atgggatagt ccctggtaga gggatgggac acgttttacc
     5341 tgaaggcgtt gtagcggctg gagcagaagc gaccttcctt aatcacgcag aacgtccttt
     5401 atcggttagt gagctgtgcg atgccgtcaa gcgagcaaag gaacttggtc tattgactat
     5461 tgtttgtgca aattctttag aagaggctaa gctcgtagct tccttgaaac ctgatgtgat
     5521 ggtttgtgag cctacggaat taataggtac aggtcaagca agtgacattt cttatatgat
     5581 tcaaaccaat gaagctgtac gcaagatgga tcctgaaatt tttgttctgc aggcagcagg
     5641 gatttcaacg gtagcagatg ttcgcaaagc acttgattcg ggggctgatg caacgggtgg
     5701 aaccagcggg attgtttgtg ccaaagatcc tgtggacaca ttgaaagcga tgattgaaga
     5761 agtaagtaaa tggaaaaagg agcaatcgac aaaatgataa cttatactga gcaacttgtt
     5821 ttgacttcaa atggacagcg agtgacgtat cataatatta ccgaacaagt aaaagaaatt
     5881 gtggcaaaaa gtgggataaa aaatggcatt tgtcttgttc agtcgccaca tactacttgt
     5941 tcagttattt ttgaggaatt catgcacgat ttagatttta atggggatga atttttacag
     6001 gttgatttaa atcggattct tgatcgaatc attcctcgag aattaacgga aaataccgat
     6061 tatcgttatc ctggtccgaa gcatcttgat ttcttgctgt ccttagatga tccagattat
     6121 gctggtgatg ctggaacgat tttaaatgga gatgcacata tccgagcatc attcttcgga
     6181 gcaagtgaaa atttcattgt caaagaggaa atactaatga caggaactgt cggctccatt
     6241 tatttcattg attttgatca aaaccgtgtt agaaatcgaa aatgccatat tttagtaatg
     6301 ggtgaataga aaagtaataa gaaacaaaca tttgggaaac taattgaatg atcacaccta
     6361 taaaaattaa tacgaaagat a
//
LOCUS       DAIGTA010000095         6271 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.101, whole genome shotgun sequence.
ACCESSION   DAIGTA010000095 DAIGTA010000000
VERSION     DAIGTA010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.101"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..553
                     /locus_tag="NOB43_002559"
     CDS             <1..553
                     /locus_tag="NOB43_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983385.1"
                     /translation="IFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKE
                     QVLAQKIEKFTACYEDMNDIFVKQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQV
                     KKDVQYVKDTKVEEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQAINIQNL
                     TKKETALNYLKSVKEWLDQQQQN"
     gene            complement(673..759)
                     /locus_tag="NOB43_002560"
     CDS             complement(673..759)
                     /locus_tag="NOB43_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCI0983386.1"
                     /translation="MFELFICPLLVGVCISVFSYWLNNRNKK"
     gene            1405..2337
                     /locus_tag="NOB43_002561"
     CDS             1405..2337
                     /locus_tag="NOB43_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI0983387.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFSQLKDLSAYKQTAGEVFIKDLARTYDHLMDLRFGRKSNGGLTIERFTMFTDFEIH
                     GEVDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRIKLFNIEHNGELTQKEKWRAKDRILNLPLGTHEAD
                     FKKQQQTEKEEAEKQSISNELKQDLLENLQNLFD"
     gene            2354..2824
                     /locus_tag="NOB43_002562"
     CDS             2354..2824
                     /locus_tag="NOB43_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI0983388.1"
                     /translation="MIDKTIKELAEEFHVSKQAIRKRLSADFRENYVQTVTRNGVKTL
                     VVSYKGYLLLKQHFLGSNTTGNQVETVASNDENSIIVFLHEQLQEKDTQIKQMQKLLD
                     QQQQLTLQANQQIEKLQEQLQLAYTEEPEEEELTSVNKENNNAITTEKKWWKFW"
     gene            2908..3212
                     /locus_tag="NOB43_002563"
                     /pseudo
     CDS             2908..3212
                     /locus_tag="NOB43_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302541.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            3487..4668
                     /locus_tag="NOB43_002564"
     CDS             3487..4668
                     /locus_tag="NOB43_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI0983389.1"
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKI
                     TKELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVL
                     TGAKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIAT
                     LPIGILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISD
                     TGRDFLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTGFNVSNI
                     HVPVRESDMIFSVIGENFGFIGSCLVIFLYFYLIYQMYKTCFKSNNLFFTYIGIGIVA
                     MIFFHVFENIGASIGLLPLTGIPLPYISQGGSAILSNFLGLGFMLCCSRYTNEKKGTQ
                     K"
     gene            4758..5027
                     /locus_tag="NOB43_002565"
     CDS             4758..5027
                     /locus_tag="NOB43_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HCI0983390.1"
                     /translation="MKKTKLLVASLCLFSSLLAFTPSVSFSQNGGVVEAAAQRGYIYK
                     KYPKGAKVPNKVKMLVNIRGKQTMRTCYLMSWNASSRTAKYYYYI"
     gene            5833..6006
                     /locus_tag="NOB43_002566"
     CDS             5833..6006
                     /locus_tag="NOB43_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983391.1"
                     /translation="MLKKTVLVLGSISLGILGFSPMLLSVIGKNNSNRELKLNSNYYN
                     SPNEELFVKQTDK"
BASE COUNT         2323 a          917 c         1010 g         2021 t
ORIGIN      
        1 tatattttcc ttgataatcg tttcaagcgg cttattcggc gttttagagg gaaataagcg
       61 cgtttctaga agtattttat taggaaatgt cactcaaaag tatgaatcag cgcgtgataa
      121 aaagaaaaaa gagcaagtat tagcacaaaa aatagaaaaa tttaccgctt gttatgagga
      181 catgaatgat atttttgtga agcaagaaaa gcgtttgacg gataaaaata tggaaacact
      241 cactcgactt tatcggaatt tgccagaaga acagcaaaaa gagtaccaag aaaaatatga
      301 acaagtaaaa aaagacgtgc aatatgtgaa agatacgaaa gtggaagaag cttgtagtga
      361 tttatttgga gatacaattc ctttttcaac tagcgaacaa gaacgaaaag aacgacaaca
      421 atcagtcaca tatgaacgct atgaaatctt gcttcaacaa gcaattaaca tacaaaatct
      481 gactaaaaaa gaaacagctt taaattattt aaaaagcgtc aaggaatggt tagatcagca
      541 acagcaaaat tgaatttgat tgaaattcat gttaaactaa acatgcaaat gttcaaacat
      601 tagatacacg aaagccccag agaggtcgga ttctctgggg ctttttttag gttgatgtcg
      661 cctttactga ttttacttct tgtttcggtt attcaaccaa taactgaata cagagataca
      721 aactcctaca agaagggggc aaataaacag ttcaaacatc agatacacct ccttccagtc
      781 gcaagactgt cggataggcg acaagttatt ataccctaca aaattaaatc tgtgtggcaa
      841 ttttaagtat ctcttatttc cgggttgtta gggcttgccc tgaccgcctg tagggcgctt
      901 taaatgccag ataaaggttt ttatactaag actgtcttaa aacggcttag acaagctctt
      961 agagcctcaa ccctcctttt tgaacaatgg ttttagcaaa ggagctggag gcgactgcgc
     1021 aggtataatg tgagagcgta gcgatcacac ctttttggcg accgtaggga gcgaggtttt
     1081 gaattagcag tttagaaaag ttcgcgaacc tgtttaaaga aaaaataatt gtttttttag
     1141 gtgggaaatt ttgtctccct cttttataat ctttttttaa acctcttttt aaacctcttt
     1201 accgtcggct gtgtccttac tcccccaagg gatacaaaat tttataggca tgaaattatc
     1261 tgtttatagg catgaaatta tctgtttata ggcatgaaat tatctgttta taggcatgaa
     1321 attatctgtt ttaggtattg tttttagaca taatatgtcc taaaatgatg tcaataaaat
     1381 catttagact ggagtaacaa ctaaatggca aatgaaatcg taaagtatga accagaatta
     1441 aataccattc ctttaagaaa atttacccca atagaaatga acttgttttt ttctattgtc
     1501 tctagaatgc gcgataaagg taatcaaaaa atacgctttt atttcagcca acttaaagat
     1561 ttaagtgcgt ataagcagac tgcaggagaa gtctttataa aagatttggc aagaacatac
     1621 gatcatttga tggatttacg tttcggaaga aaaagcaatg gtggattaac aatagaacga
     1681 tttacaatgt ttactgattt tgaaattcat ggagaagtcg ataaccctta tgtagatata
     1741 aaagtccacg aaaaagcttt gcctttactt aataatctag aaagctgggt acgtttctct
     1801 ttaacagaat ttcgagattt aaatagcagt tatgctaaaa caatgtttag attgctaaaa
     1861 caataccgaa ctcaaggatg ggctgaattt tctaaggaag attttttaga gctattagat
     1921 attcctaaaa gctatagaca aacaaatata aatcagtttg tactcaaacc aataaaagaa
     1981 gaactaactc cactatttaa aggattaact attcgtaaaa aatatggtaa aggtcgaggt
     2041 aaacctgtta ttggttatcg ttttacttgg aaagctgaaa tcaaccatgc tgacgatttt
     2101 tcaaaaggga agcaagaaga tttacgtata aaattattta atattgaaca caatggagaa
     2161 ttaacacaaa aagaaaaatg gcgtgctaaa gatcgaatac taaatcttcc gttaggtact
     2221 catgaagctg attttaaaaa acaacaacaa accgaaaaag aagaagcgga aaaacaatca
     2281 atctcaaatg agcttaaaca agatttatta gaaaacttac aaaacttatt cgattgaagc
     2341 ataaggagta tttatgatag ataaaacgat caaagaactc gcggaagaat ttcatgtttc
     2401 aaaacaagca attaggaaaa ggctatcagc tgattttaga gaaaactatg tgcaaactgt
     2461 tactaggaac ggagtgaaaa ccttagttgt cagctacaaa ggatatttgc ttttaaaaca
     2521 acatttttta ggtagtaaca ccactggtaa ccaagtagaa accgttgcta gtaacgatga
     2581 aaactcgatt attgtttttt tacatgaaca gctccaagaa aaagatactc aaataaaaca
     2641 aatgcaaaag ttactcgacc agcaacaaca actcaccttg caggcaaatc aacagatcga
     2701 aaaactgcaa gaacagttac aattagctta tacggaagaa cctgaagaag aggaattaac
     2761 ttctgtcaat aaagaaaaca acaatgcaat aacaacagaa aaaaagtggt ggaaattttg
     2821 gtaacaatta ccaactttcc ataaagaaga aatcaatttc tatagactct atctttctaa
     2881 gaataaaaaa tatgtttagg tgatcaaatg actataagta aagtaatcaa acaaaaaaga
     2941 atagaaaaac aactaactca agaagattta gctgaaatgc ttttagtatc taaaaaaacc
     3001 atttctaatt gggaaaatgg tcgaacaata ccagatacag aaaatttaat tcagtttgct
     3061 aagttatttg atttatcact agacaatatt ttgttaggag aagaaaaaat tatggtaaaa
     3121 aatcatacaa aaacactaat actattattt cattttgtaa tttttttaag tttagttttc
     3181 accttaattc agtccggatt cttttatttt agccattcaa ttgccacttg gttattaata
     3241 ttttttctaa gtttactatt aataattaat actttaatta ttatctttaa taaacataga
     3301 aacttatttc ttcacagcat atttccaatt gttttattaa tttttctata ctttatataa
     3361 aaagatagaa ctatttagta agataaaaaa gtagctaatt gtaattttcg tctaaaactc
     3421 aaaactagta aaaataactt tattgtgtta tttttattta taaattatga aaaaggacct
     3481 ttcgaaatga aaaataatag aatctacaaa aatcagttga attatgggct tttattgcca
     3541 gtttttctgc tatgtatcat tggattactt tctttatatg ttgctttata tcacgactct
     3601 tacactaatt caaaaatcac aaaagaatta attaaacaag tattgtggta tagtattggg
     3661 ttcacttcag caataactat ttattttttt aatcctaaaa ttttgtggaa attaactcct
     3721 atattttacg gattatgcat cataatgtta ttacttctct tgaaattcta taatccacaa
     3781 ttagcagtct taactggagc aaaaaattgg ttttatattg ctggtttttc gtttcaacct
     3841 actgagttag tcaaaatagg atacaccctt atgctagcta aaataaccgt caattatcag
     3901 caaaaatcta ttactagtaa tacgaaagat gattggattt atttacttaa aacttttatt
     3961 gctactcttc caataggaat attattattt tttcagaacg atctaggaac aatgttagtc
     4021 ttcattgtta tttatatttt tattttgttt acgtctaaca taaatataaa aataattgcc
     4081 ccaataatcg ccattggtgt tgttttatcc ttaatatttt tatatttggt tatatcagat
     4141 acaggaagag atttcttatt aaaaatagga tttcacgact atcagtttaa aagaatagac
     4201 tcatggttga atccattttt agatccaaat ggatctagct atcagttagc aaatagttta
     4261 attgctattg gctctggcgg acttttaggt actggtttta atgtatcaaa cattcacgtt
     4321 cctgttagag aatccgatat gatattttct gtaattggag aaaattttgg ctttatagga
     4381 agttgtcttg taatattcct atacttttat ttaatttatc aaatgtataa aacatgtttt
     4441 aaaagcaata acttattttt cacctatatc ggtataggca ttgttgcaat gatttttttt
     4501 catgtttttg aaaatatagg tgcaagtatc ggattactac ctctaactgg tattccactc
     4561 ccctatatta gtcaaggtgg ttctgccatt cttagtaatt ttttggggtt gggatttatg
     4621 ttgtgttgta gtagatatac taacgaaaaa aaaggaacac aaaaatgaat tcaaaataac
     4681 actttatgaa tagaatgtct atttcaataa aaattatgat accttaaagt taatcattaa
     4741 aaaaggagtg tcataatttg aaaaaaacaa aattattggt agctagtttg tgtttgttta
     4801 gcagtttatt agctttcacc ccttctgttt cattttctca aaatggtgga gtggttgaag
     4861 ctgctgctca aagaggatat atctacaaaa aatatccaaa aggtgctaaa gtgccaaata
     4921 aagttaaaat gttagtaaat attagaggta aacaaactat gcgtacttgt taccttatga
     4981 gttggaatgc tagtagtaga acagccaaat attattacta catttagtaa aaacaaaaca
     5041 ttctttctat acaataaaat agcgtataga gaggatgttt ttaatttgaa aaggagtggt
     5101 tatctttatg aaaaatagat catttgctat attagtatta tccgtaattt tattagatat
     5161 attgttaata acattagctt taaaaacttt aaatttagta acaagttttg tcattatacc
     5221 agtaattata ggaatgtcta tttatttcat caaaaaaaat aaacaatttt tttgaatgaa
     5281 attacgggcg aaaataatca ctcaaaatta ttaataaaaa cgaatcaact actttttctg
     5341 aagaaacata caaccgtaaa caacaattgt tgtttacggt tgtaaattat caaactatat
     5401 ggtgacttgt tgcttaaaat aggttgaaat ttcgtttatt ttttttgaga aattttaccc
     5461 acgtactacc catgtaccta tccacgtatt acccatgtac ccccccatga caaatgggcg
     5521 gaggggcttg cggcgcttgg tattaaaggc attatccgcc tcccaggttt ctgaccattt
     5581 tctctcataa gtggggtttt taccgcgttg agagaaaatg gtcagaaacc taaacgatcg
     5641 gcaaagaaaa cataccaagc gccacaagca aaaaaagtta gagtaacttc cagaaaagaa
     5701 aaatttttag aacaactttt gaaaatttga ttttgattta tatccgttca atttaaacat
     5761 ttgataaact gaaggctagt atttaaaatg tgtatacaag tggtagcgtt aaaaaaagtg
     5821 gaggtataac ctatgttaaa aaaaactgtg ttggtactgg gttctatttc tctaggaata
     5881 ttaggtttta gccccatgct attatccgta attggaaaaa acaattccaa cagagaactt
     5941 aaattaaatt caaattatta caacagtcct aacgaagaat tgtttgtaaa acaaacggat
     6001 aaataataaa aaagactgct ctttcgagca gccagttaaa aaataatgag tgtttattct
     6061 tgaaaaagca cgcgcttatg aagcgctacc aaaaatttac catattttac aaaaaataac
     6121 aagtcttaaa aaaatgacag ataaaaatgc acaaagaatt agatatagat aaccgcgaaa
     6181 aatcaagctt tagaaagttg cttttagcta gaccaattaa aaatcacaaa gtgagcgtct
     6241 ctatccattg gtagaggggc tacttggcat a
//
LOCUS       DAIGTA010000096         5983 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.102, whole genome shotgun sequence.
ACCESSION   DAIGTA010000096 DAIGTA010000000
VERSION     DAIGTA010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.102"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(48..917)
                     /locus_tag="NOB43_002567"
     CDS             complement(48..917)
                     /locus_tag="NOB43_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HCI0983392.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(1209..2819)
                     /locus_tag="NOB43_002568"
     CDS             complement(1209..2819)
                     /locus_tag="NOB43_002568"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HCI0983393.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4012..5352)
                     /gene="glnA"
                     /locus_tag="NOB43_002569"
     CDS             complement(4012..5352)
                     /gene="glnA"
                     /locus_tag="NOB43_002569"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HCI0983394.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(5380..5772)
                     /locus_tag="NOB43_002570"
     CDS             complement(5380..5772)
                     /locus_tag="NOB43_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0983395.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         1755 a         1278 c          982 g         1968 t
ORIGIN      
        1 caaaagtcgt tctccattcc tatatatcgt atctgttatg tggatgctta cgctttgtta
       61 gctgaaccga accagtcgat atgagattta gcatcttcaa cgattgctgc tttacctgga
      121 gctaataatt tacgagggtc gaatccttta ccttctttat ctttaccagc ttcgatatat
      181 ttacgagtag ctgcagcaaa tgataattgg aattcagtgt taacatttac ttttgagata
      241 cccattgaga tagctttttc gatttgatct tgaggaatac ctgatccgcc atgtaatact
      301 aaaggcatgt ctggacctac agcatcagca attgcttgta agtggtcaaa agctaatcct
      361 ttccagtttt ctggatattg accatggatg ttaccgatac cgcaagctaa gtagtcgata
      421 cctgtagcaa ccatttgttt gcattcttca atatcagcta attcgccgtt accgatgatt
      481 ccgtcttctt ctccgccgat tgaaccaact tcacattcaa ctgagatacc ttttgcatgt
      541 gctttttcaa caacgtcttt agctaatttc aagttttctt caaatggtag atgtgaacca
      601 tcgaacatta ctgaagtata gcctaattcg atacattcca aagcagcttc gtaatcacca
      661 tggtctaagt ggatagcaac tggaacagtg atgttcattg cttcaactaa atcagtgatt
      721 aaatctttac agattttgta accacccatg tatttagctg cacccattga tgtttggata
      781 agtactggtg cttgttttgc ttcagccgct tcaaggattg cttgagtcca ttccaagttg
      841 tttgtgttga atccgccgac agcgtaaccg cctttacgag cagcttttaa aaattcagct
      901 cctgatacta ctggcataat aaaattcctc ctaagttttg taaaactaaa tttgttaaga
      961 caattcttaa ccaacgaccc tattttacca aacatttcgg tagttttcta ctaaaatcaa
     1021 tgaaaatgaa aattttcaag aagttttttg caaaaaataa aatatccaat agcgctttaa
     1081 tcgaaaaaag tcttttgctt tctatctttt ttcctacaaa taataacaaa tcagaaaaag
     1141 agaaaagtga caagaaaatt gcttatcccc ttctcttgct acttttctct ttctatcaag
     1201 ttcaaaaatt attttgtttc gtgatctgct aatgatgctc cgacaaatgc tttgattaat
     1261 ttttgcgggc gatttggacg agaaatcaat tctgggtgga attggcatcc cacaaagaat
     1321 tttttctctg gcagctctac gatttctact aaacggttat ctggtgagac acctgaaaag
     1381 actagccctt gttcttcaaa caattgacga tatttgttat tgaactcata gcggtgacgg
     1441 tgacgttctt gcacaacatc ggctccatca tatgcttcag ccgtcttcgt tccttttttg
     1501 attttacatg ggtataatcc aaggcgtaaa gttccaccca aattctcgat gttttcctga
     1561 tcagccatta aatcaataat attgtttgct gtatctggat tcgtttcagc tgatgacgca
     1621 tcttctaatc caacgacgtt acgtgcaaat tcgacacaag ccatctgcat accaagacaa
     1681 atacctaaaa acggaacgtc attttcgcga gcataacgaa tcgcttcgat tttcccttct
     1741 actccgcgat caccaaatcc accaggaacc aagattccat ctgcgtcttt caaacgttct
     1801 tctacatttt ctctcgttaa ttcttgtgct ttgatccaat cgatctcgat gtctgaatta
     1861 taggcgaaac cagaatgttt caatgcttca actactgaga tatatgcatc tggtaactcg
     1921 acatatttac cgacaagcgc aatccgtact tttttcttca agttcaagac acgttcttct
     1981 aattctttcc attctgtcat gtctgcttct ggtgtatcta gttttaaatg gtcgcaaaca
     2041 atttgatcca ttccttgtgc ttgtaaaact aatgggatgg agtaaagtgt atctacatct
     2101 ggcgactcga taactgcttc tggttcgaca tcacaaaatt gtgccaattt gtttttcacg
     2161 ctttgagaaa caggttgctc tgtacgtacc accaaaatat tcggttggat acctaaacca
     2221 cgtagctctt ttacactgtg ctgcgttggt ttagttttca tttctccagc agctttcaag
     2281 taaggaatca atgttgtatg gatatacata acattatctg taccgacatc tgctttcatt
     2341 tgacgaagtg cttcaaggaa tggcaaagat tctatatccc ctactgttcc ccctacttct
     2401 gtaatgatca catctgaatc agtcatttta gctgctcgca tgattttttc tttgatctca
     2461 tttgtaatat gaggaataac ttgaacagtt gctcccaagt attcgccctt acgttcttta
     2521 cgcaaaactt cagaatagat ttttcctgtc gtcacgttgg agtatttgtt caaattgatg
     2581 tcaataaaac gttcgtagtg gcccagatcc aaatctgttt cagcaccatc atctgttacg
     2641 aatacttctc cgtgctgata tgggctcatc gtccccggat ccacgttgat gtatggatca
     2701 aatttttgga tagttacttt taagccgcgg tttttcaata agcgtcctaa agaagctgca
     2761 acaatccctt ttccgattga tgaaacgaca ccgccggtca caaaaatata ttttgtcata
     2821 agttcaaaaa ctccttttta atttatgtgc aggaaaagtc tcagacaata aacaaagctc
     2881 cctattcttc aataagaata gggagccgaa atttctgtaa acttctgacc ctctaaaagg
     2941 gtgcccaagg tgtataatac aagctgacta agggaaagtc aagtactcaa atgaatacta
     3001 tccgcttaca attttttctt tttcgatatc ctttgagaaa ttatttctta agtcctttat
     3061 gagtgcaaaa aaaatttaac ccacataata agcttgatat aaacatagct aacgttaaac
     3121 ctaagcaaat cagaaaatcg ttactgaaaa attttaagtg aaataataga taaaaaaata
     3181 aaacaaacat tatgatagat aatatcccac ctaacaaaga actacttttt cctacttgca
     3241 gcaacagttt atatagctta tcgtagaaac aatctttttc tttcaccctt atttacctcc
     3301 tttacgtaaa aaacgtagtc cacagttctc ggatttttgg catatctttt ctattaaata
     3361 atatcaaaaa caaaacaatt ccactaattt tttcaaagat gacctttttt tcaacaaaag
     3421 tgccttgtag ggattcattg aaggtaacga atcacataag taaaaaataa ggagatgcga
     3481 caaaagtcgt gcctccttat ttctaaataa acggtgttct cctgccaact cctcggtcac
     3541 aagtcacaat atccatcaaa catgagaagc tgtttttgaa attatttctt gtgattcgga
     3601 gttaaatggt aggctcacaa cctctggata aacggtattc aaaagccagt ttctcggtat
     3661 taagccaaat ttatgcaaaa atgtagaaag ccattttcac aaaatttttc ttaatactcg
     3721 aaactaaacg tctttttcaa aacctcttgg taaacggtgt tcaaaagctt gcatctgcgg
     3781 taataagttc agccaattca aaaacaagaa aagctgtttt tgcttggcta ttcttattac
     3841 ttgttgcagg gcagcttttt cacaacctct ccactaaacg gtgttcaatc agctgaccct
     3901 cggtattagc tcaaaaaacg gcaaaatatg aggaactatt tttccgttag tttctctaat
     3961 actcaggtca aaacgctgat ttcacagcct ctaattcacg gtattcctgt tttaataaag
     4021 ttctagatat tgttctcttt cccactcgga aacagtttgt ctgaatgccg cccattcgag
     4081 acgttttgct tcaacaaaat ttgagaagat atgttgtcct aatgcgtcaa tcattacatt
     4141 atccttacgc aattctttga tagcattatg gatagttgaa ggtaagtcct ggatatgtgc
     4201 agcttctctt tcttcctcat ccattacata aatgttacgg tcaacagctg ctggcggtgt
     4261 gatctgatta cggataccgt ctagtcctgc ttgcaacaat actgccattg ccaagtatgg
     4321 gtttgcagat ggatcaactg accgcaattc caaacgtgtg gataaaccgc gagattctgg
     4381 tacacgtact aatggcgaac gattacggcc actccatgcg acataaacag gcgcttcata
     4441 acctggaacg agacgtttat aagaattgac tgttggattg caaacggctg tgtaggcacg
     4501 agcatgtttc agcaaaccac ctaagaaatg ataagctgtt tcacttagtt ccaattcacc
     4561 gtctttatca tagaaaacat ttccttcatc attgaacaaa gacatattgc aatgcatacc
     4621 agaaccattg atcccaaata acggtttcgg catgaaagtc gcgtgaagtc catgcttgcg
     4681 tgcaatcgtt ttgacaacga gcttgaaggt ttggatatta tcacaagcat ctaccacatc
     4741 tgcatattta aagtcaattt catgctgtcc tggcgctact tcatgatgtg aagcttccac
     4801 ttcaaagcct agactttcta attccaacac gatgtcacgg cggcaatttt cacctaaatc
     4861 tgttggtgca aaatcaaaat aaccaccttt atcattcaag gtcgttgtga tcccaccgtc
     4921 ttcgtctaat ttaaataaga agaattctgg ttcaggtcct aaattgaaag aggtaaaacc
     4981 aaggtcgcgc atatctttca atgctcgttt caaattcccg cgaggatcgc cggcaaatgg
     5041 tgtcccatcc ggattataga tatcacaaat taaacgagca acttttccat gagcactttc
     5101 ccacgggaag atcatccaag tggagagatc tggatacaaa tacatatcgc tttcttcaat
     5161 tcgaacaaat ccttcaatcg aagaaccgtc aaacatcatt ttattttcta atactttgtc
     5221 gatctggctc actggaactt ctacattttt gatcgtacct aagatgtctg tgaacatcaa
     5281 tcgtaaaaat cgtacgtttt cttcctcaat gattcgtttg atttcttcac ctgttatctg
     5341 tttctttacc atggtatccc tcttcctttt ttaatttatt cagtcaaaga attgtctttg
     5401 caatccttgc gactgataat gacctgtttt gcttaaccca ccttgcgcca aaatctcatc
     5461 acgaaaaatt tgtcgaacgt catgatctgt caacggcttc ttgttttttg cttcttgttt
     5521 tttcgcctgt gccatttcgt atacacgttt gatcccagcc atattcaatc cctctgaaag
     5581 atagtcttta atctcaagca acatatcaat atcattcagc gaatacatac gtcggtttcc
     5641 ttcgcttcgt tccggatgaa ctaaatcttg ttcttcataa tagcgaattt gccgagcaga
     5701 caaatcagtc agcttcataa ctgtaccaat tggaaatacg gacatagatc ggcgcaattc
     5761 cttttctccc atcagacgtc ccctttcgtt ttataagttg gctaaagtgt accaattaaa
     5821 aaaaatattg tcaactgcat atgttaggtt ttctaacatg agatctctat tttttataaa
     5881 ataacaaaaa aataagaaca caaaaaaggt atctagttga ttttcgtacc agataccttt
     5941 tattttttat tatactgtac tatcctttat tagtgttttt att
//
LOCUS       DAIGTA010000097         5956 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.103, whole genome shotgun sequence.
ACCESSION   DAIGTA010000097 DAIGTA010000000
VERSION     DAIGTA010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.103"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            446..1018
                     /locus_tag="NOB43_002571"
     CDS             446..1018
                     /locus_tag="NOB43_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCI0983396.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            1163..1867
                     /locus_tag="NOB43_002572"
     CDS             1163..1867
                     /locus_tag="NOB43_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0983397.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            2095..2433
                     /locus_tag="NOB43_002573"
     CDS             2095..2433
                     /locus_tag="NOB43_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983398.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2418..3273
                     /locus_tag="NOB43_002574"
                     /pseudo
     CDS             2418..3273
                     /locus_tag="NOB43_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
     gene            3420..3653
                     /locus_tag="NOB43_002575"
     CDS             3420..3653
                     /locus_tag="NOB43_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HCI0983399.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3851..5755
                     /locus_tag="NOB43_002576"
     CDS             3851..5755
                     /locus_tag="NOB43_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI0983400.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDSA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPTEKVKIS"
BASE COUNT         1908 a          992 c         1347 g         1709 t
ORIGIN      
        1 aaaaaaattc ttttcaattt ttatttatgg tgtgacataa ataaagtaaa gttattcttc
       61 taggttaatc ttattaatgc tctttctcac tagtgttgca tgcaacacta gtgagaaaga
      121 gtattaaata tactgcaagg taagacattt ggtaattgaa gaataacaag caaaaaaata
      181 gcagtcaggt ctcttgacaa agtatagttg ctattctttt tttaggccct actttaatga
      241 aatttttgtt tggaggggac gacttcattc ctttgattat ttcagttgaa tttaatagag
      301 aagcctggcg tctattaaga aatacttttc ttgatgagcg tcaatttttt taacggaaat
      361 ctatcctata ctaaattcag taaagaaaaa ggaggaatca aagaaagcta ttttaaacaa
      421 accaaaatta taggaggaat aaatcatgac tgaaaataaa gctactcaag aaagaacacc
      481 ccaagaaaga ttgcaagaag aacaagaaca caaggaacat gttcatcata cgaaaattaa
      541 tgcagcggcc attgcggatc atcttttagg caacatgcat acattacatg tgaaactgca
      601 ccaatatcac tggtatgtaa aaggagccaa tttctttacg ttgcatgaaa aatttgaaga
      661 gttgtataac gaaaatgaaa aatggttcga caaacttgcg gagcgtctaa ttacttctgg
      721 gcataaacct gcttcgacaa cggttgaatt tgaaaaatat tcgatgcttt cggaagatgc
      781 agttaataaa tacgctaaag cagaagacat ggttgaaaat attatcgagg acttcagaag
      841 cactcgtgac ctaactattc gcgcgattcg tttagctcaa gacgagggtg acgatgcttt
      901 agaagataca ttgattgctt ttaaaaatga cttagacaag aacatttgga tgctgcaagc
      961 gttcattggt aaagaagcat tagaagatga tgacgctctt gatgaggatg aagattaagg
     1021 taaaagtaga agctgattta gggattggaa ttctttccag tcctttttcc attttcttga
     1081 tgtgcatcaa tttttttgta gtaagagact tatataataa aagcagcgaa tataaacaaa
     1141 ataaataaag ggggagaatg aattgactaa acatacccat catgaaattg gcgaccacgc
     1201 agcctgtatc cgcttggttc caatattcaa tcacttagag gatagcgcga tgaattacat
     1261 tgctgaaaaa gcccacacga aacagtatca aaaaggagag tttctgtttc gttcacaaga
     1321 aaaagaggat actttatata ttatcaatcg tgggaaaatc cgtatttatc gattggcaga
     1381 ctctggcaaa gagcagctag tgcggatctt gaaccctggt gatttcaccg gagaatggac
     1441 cttgttcaac ccggatgcag tacacgagga atatgccgaa gcaacccgag ataccgttgt
     1501 ctgtatgatt cagcaaaaag atgtccaaga ttttctggaa caatacccag ctatttcttt
     1561 aaaactattg gcggaaatgt ctaaacggtt agaaagttca gaacgtcaaa cgacacaagt
     1621 agccgtggag agtgtcatta cccgtttagt tttgtttttg gcagaaaatg tggaacctga
     1681 aatgggcaac tctcccacca tcaccctgcc gatggcaaaa aaggacattg cttcctattt
     1741 aggaacgaca cctgagacca tcagtcgcaa atttggagaa ttggaggacg aaggattgat
     1801 tcaacagctg tctgggaaaa ggatcaagat tcaggattta gatgatttat tgctttacag
     1861 cgaataatcg gacacacttt tttctacacg ttggtgttct gtcgctcttc attaacaacg
     1921 ggacagaact cagtgctttt gcttccatct gtccgttttt ggctttttta agacagaact
     1981 accttcattc attggaaaaa taaaagcaca aacatgataa ccctcaagtt tttttgtttt
     2041 atttttcttt aagatagggt tgtcgaacaa aacgtaaaaa taagtagggt gaatgtgcat
     2101 tgtttttggg tgatagttgc catcacgttg tcagcagcgg gggcattctt tgtcgtccct
     2161 ttcaccaaga acacgattgg cggcgaagca aaaacgtcta acgttgttga ggcagatagg
     2221 ttagctatgg aaaaagaaga ggaagttgta aaaggagccg gcgtaatcgg acacggaaaa
     2281 gtggcgtatt acgaagcgag cgaccaggga gataaaagtg tattcactgt ttggtttcca
     2341 tggagcttag ccggaatctt gttcagcatc accatgacta gaatgacgcg aaaaattgaa
     2401 gaaatggaac aaatagaatg ggattcgtat taggcgtttt gaatccccat gtggtggaga
     2461 ttggttctgt tgtgattcat tggtatggag tcattattgc agcgggcata ttagcggctc
     2521 tccagttgag caccaaggaa gcaaagaaaa aaggactgga agaggatacc attatcgata
     2581 tggccttatg ggcaattccg attggactcc tcggcgctcg gctttattat gtgttacttg
     2641 aacttggtta ttatctgcaa aatccaggac aaatccttgc gatttggaat ggcggcattg
     2701 cgatttatgg gggattgatt gcaggagggg gtacgctata ttggtatgca aagaaaaaag
     2761 gtacttcttt ggcactcgtt cttgatattt tagcgcccaa tgtattgtta gcccagttcc
     2821 attggtcgtt ggggcaattt tatgaatcag gaagctcatg gtgggccggt tactcgtcaa
     2881 ttcttggaaa atctttattt acctgaattt atcattgaac aaatgaatat gaatggtacc
     2941 tactaccatc cgactttttt atacgagtca ttgtggagtt tgttgggctt tgtcctcatc
     3001 gtcactatac ggaaccgaaa acagcttttg cgtcaaggag aagtcgcttt gagttacgtt
     3061 ttgtggtact cagtgggtcg gttcttcatt gaaggtatgc gaacggacag tttatggatt
     3121 ggcgagtgga tccgcgtttc gcaagccttg tctctggccc tgtttattgg cgcgattgta
     3181 gtatggttta tacgcagaca agattatcca ccaatttctt attattctga tggcaataag
     3241 gggcagaaaa agactattaa gatggtgaat tgagcaaaaa gataaaaaga agtgcaaaac
     3301 ttgatatgcg tcaattttcg tttgctaaaa gtgagctata ctacagttgt aaagaggaaa
     3361 aggcagtgtt cattaatctg ctgccgataa aataaaaaca cataaaggag ataggaatta
     3421 tggaaaaagc tatattgcaa ttagaaacgt tgtcttgtcc aagttgtatg caaaaaattg
     3481 aaggtgccgt gaaatcagtt aacggtattg ataaagacag cattaaagta ttattcaact
     3541 ccagcaaagt caaaaccaat tttgattcag ctgtcacttc gattgaagag attcaaaaag
     3601 ctatcgaaaa cgtaggctat ccggttctta aagcaaaagt caaggccgtt taacagatta
     3661 aatgaactag gcaattctgg aagaaaagct atttttccag gattgctttt tttgttgcaa
     3721 tccgattcga ggtgcttaga aacgataaaa gagaactttc taaacttgat gtcagtcaat
     3781 taattactta ggcaattatc ttatactgtg tttatcaata aaagagaaat taaatttgga
     3841 gggaaaaagc atgcaacaat atatattaag caagaaaaat gttatcaccg tcatcagtgg
     3901 attgttaatc gtactcggtt tcttcagtca ctttgtttta gaaaacgtag gactttcaga
     3961 gtggtctttg atcatcgcct ctgtctttgg gattacgcca attgccattc aagcgtttca
     4021 agcaatgaaa gtcaaagtca tcagtattga tgtcttagtc agtattgcag cgattggtgc
     4081 gctttttatt caaaattatg aagaatcggc tattgtcacg ttcttattct tattcggaca
     4141 ctacttggaa caacgaacat tgaaccaaac gcgatctgct atcaaagaat tgactgaaat
     4201 ggcacccgaa agcgccttga aacaaatgga taatggcgaa tttgaagaag tagaagtgga
     4261 tgatatagat gaaggggata tcttgctcgt taaaacgggt gcgaaagttc cagtagatgg
     4321 catagtcctt acgggtgaag ggcatatcaa tgaagctagc attacaggtg aagctattcc
     4381 ggtcaacaag ctagctgatg cagaagtttt tgcaggaacc attttagaaa acggaacgat
     4441 tcaaatcaga gctgaccgag ttggtgagga caccacattt ggaaaaatta ttgaactcgt
     4501 ggaagaagca caagattcta aatccgaagc ggaacggttc attgatcgct tttctaaata
     4561 ctacacacca gctgtcttgg ttctggcaat tgttgtatgg gcgttcagtc aaaatattga
     4621 gttagcaatc accatcttgg ttctaggttg cccaggcgca ttagttatcg gagtgcctgt
     4681 ctcaaacgtt gccggtattg ggaatggtgc tcgtaacggt gttcttttaa aagggagtga
     4741 agtcattcaa gacttcagta atgtggatac aattgtattt gataagacag gtactttaac
     4801 tgtcggaaac ccaaccgttg cagcgactga actgtatgaa aaagattctg ctgaaacgct
     4861 tggctatctg gccagtgtgg aacgggaatc agatcatcca ttagcaaaag cggtcttaaa
     4921 tcaaattgga gaaacaaact tttatcctgt tgaaggaact gaagttgtga aaggcggcgg
     4981 aatcgtttca agtgtagctg gacatagagt ggctgttggg aatgtggcct tgatggaaaa
     5041 agaaaatgtc actctcagca aaaaagtgca aaaagatgtc aaacggtttg aacaacaagg
     5101 gaactctctc gttttgacag cggtcgacgg tgaattaaaa gtactgatgg gcattcgcga
     5161 tcaagtccgt ccgggtgtga aagctaattt gcaggaatta aaagacttgg gcgtgaaaaa
     5221 tctagtcgtt ctttcaggag ataaccaagg aaccgttgat gtggtcgccg gcgaacttgg
     5281 tttgaccgaa gctcacggct acatgttgcc ggaagacaaa tcggcttata tcggaaaact
     5341 tcaacaacgt ggtcaaattg tagcctttgt tggagatggc gttaacgata gtccgtcctt
     5401 agctttagca gacattggaa tcgcaatggg aagcggaacg gacgtagcga ttgaaacatc
     5461 cgatgtcgtt ttaatgaact cgaacttcag caacttgcct cacgcattag gattagtaaa
     5521 agccaccgca aataatatga aacaaaatat cgtgatttca gttggagtag tgttggtctt
     5581 gttgaccagc gtcttcttca gcgaatggat gaatatgtct atcggaatgt tggttcatga
     5641 aggtagtatc ttggtggtaa ttttcaatgg catgagatta atgaagtata agttgaaagg
     5701 tcggaaagaa caaaaagaag tatcagcacc tacagagaaa gtaaaaatat cttaagaata
     5761 aattagaaga ggctgagaca atagtccatc cttgaaatga caaaagcgga aactcagatt
     5821 tttaaatctg ggattttccg cttttttgag ttcttgaaaa aaaaataaga gtatagagta
     5881 tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa gggagcgtca ataattttgt
     5941 gtaaataact cgtcct
//
LOCUS       DAIGTA010000098         5900 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.104, whole genome shotgun sequence.
ACCESSION   DAIGTA010000098 DAIGTA010000000
VERSION     DAIGTA010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.104"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(96..698)
                     /locus_tag="NOB43_002577"
     CDS             complement(96..698)
                     /locus_tag="NOB43_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983401.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            821..1021
                     /locus_tag="NOB43_002578"
     CDS             821..1021
                     /locus_tag="NOB43_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983402.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            1033..1359
                     /locus_tag="NOB43_002579"
     CDS             1033..1359
                     /locus_tag="NOB43_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983403.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            1512..2564
                     /locus_tag="NOB43_002580"
     CDS             1512..2564
                     /locus_tag="NOB43_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0983404.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            2640..2858
                     /locus_tag="NOB43_002581"
     CDS             2640..2858
                     /locus_tag="NOB43_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983405.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            2845..5523
                     /locus_tag="NOB43_002582"
     CDS             2845..5523
                     /locus_tag="NOB43_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983406.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            5514..5711
                     /locus_tag="NOB43_002583"
     CDS             5514..5711
                     /locus_tag="NOB43_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983407.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            5715..>5900
                     /locus_tag="NOB43_002584"
     CDS             5715..>5900
                     /locus_tag="NOB43_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983408.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAED"
BASE COUNT         2265 a          777 c         1104 g         1754 t
ORIGIN      
        1 tatcgtgcac cgctttttgt tgtgtacttt tgtattgaca taactaatct ctccaatctg
       61 ataacttggc gagttggctg attgaataat tagttttatt gaagttttga tattaatcga
      121 gctgttatct ctctttttag attgttaacc tgtacttggg ttaagttgcc aaataactca
      181 gattctaact cttttctttc atcgatattt aagtttaaag ctttattaat aaacttcttt
      241 tgtttggcaa atagaatcgt gtattcaaag gagtcctcta gaatactttt taaaaaaaga
      301 aagtcggagt catcttcttg aagtttgact tcaagtaaag aagtcatgga aaagtataga
      361 ttagataatt cagtaaaata atctgagtca agactggcaa tattcttgac tattttgtcc
      421 tttttttcta aacgagcagt ttttattcta tcaagattag gttgttctat ggaatttgtt
      481 tcgtctaatc ccatcaaata acttacagga acatggaaat aatcagcaag gatattccat
      541 gtttcagtat ttctaggatt tcgctcacca cggtaatagt tcgtaagagt tgtatagtta
      601 ataccagttt ctgtactaat ttgtttaatg gtctttttac tggaatcaat ataaaatttt
      661 attctattca aagtaacgcc ccctatagta aattccaaac tattatagca tgaaaaccac
      721 aaattgagta atattttaat tgatattact cgttttgtgg tttaaaatgt gcttattaag
      781 ataaaaacca caaagtgaat aatttgaaag gaggcgctga atgataactc ttaatgatca
      841 attcattaga agcttaagaa gacatagagc cgatcttata cttactaaaa acgatgcagc
      901 aaaattgata ggtataaatc ggaaaacata tgtcaaaatc gaaaatggga gcaaagaaag
      961 tattagagca tctacttatc aaaagttggt aaattggtta cttaatgatt tgaaaatcta
     1021 aataaataca acttggcgag ttggctgatt gaagaaatag aaaatgagag gagaaaaata
     1081 atggatgcag gaattacagt aatgttagat aaacaacaaa cgaatcaatt gaaaaattat
     1141 gtttttgaaa tgacaaaaga ggctattgat caagcaagaa ttgataccgg attagaaaga
     1201 ccatttctaa aaggaaaaga gatggctaaa tatttgaatg tatcatatac aacttttttg
     1261 aaatttaaaa gaatgggatt gccagttatt ttattagaaa aaatggagtt gttttcaaaa
     1321 gaagaatgca aaaaatggat attgagtcat caaatttaaa aaacacctcg ttttttaaat
     1381 ttgatgaagt agaaaaaatt aaaaagagtg ttcccgtcag tttgcagatc gggggaacac
     1441 tcaataataa agttctgaga aaactttatt tgaatctatt atagcaaata aaatcagaag
     1501 caggtgtgac aatgaatgaa aaagaagttg aaagcttagt tgaaaagcaa ggctattcta
     1561 attctgatat atatgcagaa ttatactatc aatatcctat ttttttaaac gtaaatgaaa
     1621 aatataagaa aatgaaacta agttctaagt tagtttatat gttactaaaa gatagaaata
     1681 gactttcatt gaaaaataac ttgtatgatg agaatcaaaa aatttttttg atatttgaaa
     1741 tcaaaaatct cgtagaaatt tcgggaatgt caaaaaatac aatcttatca gcactagatg
     1801 aacttcaaaa agttaaactt cttgtgaaaa gaaaaaatgg cttcaataaa agtaaaatgc
     1861 aaatgttccc aaatttttat tatttgttaa agcctgttct gtgcaaagat gatgtttata
     1921 aaattaataa gataacccat caagaaaata gacaaaaaaa cttgatagtt caaaatttga
     1981 actatggaac aaatcaatat tctgttgata attcaaaatt tgaactatgc gacacatcaa
     2041 tgaaaacaag agacaaaaac aattttgctg atagttcaaa aaatgaacta gaattatata
     2101 agtcttataa agatagtaaa gatattaaag aatcacataa tgatgatctt cttgaatcac
     2161 tttcaactaa aaataataaa ttagatgaag aattgatcga aacatttatt gaagaaaatc
     2221 ttcttaaaca aatatgggga gaaagtattg tgaattgctt aaaactggct agcaatagtg
     2281 attatcgtca attcgacaac tggtacaaaa aattcaaata tgcgattaga tctgctgaaa
     2341 aagaacaaaa aattcaactg aaaattatct atgaaatttg taataacaag tattttgtag
     2401 atcatgttag agaacagcta tcaatgactt tacgtgactt gatacgaaga gcaaaaacag
     2461 atcatcgtat caaacaaaaa gacgattata tctttgcttc tctaaaaaat aaagcgttag
     2521 aactaattga attgcaaatc agcgaaggaa tagataagca ataagaatag aattgagtca
     2581 aatgaaatgg aggggtatct ccacttcatt tgagaacttt gaatatagga ggggttattt
     2641 tgattaaaaa tcgtttaata gatcaagttt ggtgtctaga tcaaaataca gatagtctcg
     2701 aattaatcga gactatttgc ttcaacacta tagttctcga tttaagagct gaaaatgata
     2761 attgtgtaac tcatgtcata attaatcaaa aaatggctca gaagctctct gagagcctca
     2821 gaaaatgggc taagggaggt aacgatgaaa ataattgaaa aaaagattgc caataaaaaa
     2881 ataaattggt tggttgttaa ttttcttgtt ctgatagcta tgattatttt tacaagtaat
     2941 attgctcatg cgagtatttt caattggttt gatgacacaa aaagtcaaac agagtttttg
     3001 aataattctc tttatagacc ttacctaaaa aagtacaatg gagatttcct tagtcagttc
     3061 gggatttggc tcggatgggc tgtggtaaaa ggcatgttta ctgtgacaga ttcgattcaa
     3121 aatatgattc cagatgtgct ggatttgttc aatttcattg aaagtacagg gctaaataat
     3181 gtttatcaat cagccgtaaa tacaattgtc attggattaa tgatcctttc attgatgttt
     3241 gttggttaca aaatgattac tggaaaagga acagtggatt taaaatcggt tggaatgaac
     3301 gtagtgatgt ctatagcatt aatactttta atgccaacca tgatttctag tggtattcaa
     3361 tttgctaaaa cattttataa ggactctact acgattacaa attcagatga cggagtcgct
     3421 tggtcattga taaaacaagg agtaacagat ttagcatata ttaataaaac agatcagtac
     3481 tcaagcattg ataaaacgga ggatcgaaat aatttaacac gaaaaaattt tcaacagacg
     3541 gatctcacac aagtgttaac ggataaagtg attgataaat tggaaaaaga aaatccaatt
     3601 gcggacaatc ttcgttatga attagttgaa aattctaata atgaatttgt tgctacaaag
     3661 ttttctgaca acttcttatc aacattttct gatagcttga aatcaggcta ttaccgatac
     3721 caagcaaatc tatgggggat ttcaattggg ttgacagcgt tagcaatcgc ctatgtgttc
     3781 agcgcgtttg tgatcattac agcaatacta gaacttgcat ttaaacgtgt gttaggtgtt
     3841 cttgtttttg caacagatat tgagacagga cagcgttcaa aagttgttct atcagatatt
     3901 ctacaatgtt acttaactgt tgggtttcaa ggatttgggt tatcaatgtt tgctatgttt
     3961 atcaattttc tgaactcagg acaaggtatc tcaacaaata tttttataaa aacaattgct
     4021 tatatctgtg ccgtttttgt tttaatcaaa ggcagtggaa cagtcatgag atactttggt
     4081 gttgatattg gactcaaaga aggctatggg caacttgctt ctgcttttgg aatgggcgca
     4141 atgctgttta gaaaaggatc aaatggattt aatcgtgcta aaggaagcgg agaaggagaa
     4201 gatcgaaaac cagaaaagaa tttcggcgaa actctatcaa aaaaagctgg caaaactgga
     4261 agagctttgg gatatgccca tgaacgtgga ttatccggtt tagcttcaga tggagctaca
     4321 atggctagtg aaagagcaac aaaaccattt aagagtatgc gtgatatagc taatgatacc
     4381 aagaataagt ttaaagaagg tttagatgat ggtacagtgt ccgctattaa taaaaatagc
     4441 aaacctatgt tagctaaaaa taaagaagat gaaactggaa aatatgctga ttccgtgcca
     4501 acacgtcttt cagatagaaa agatggtgct aaagttgaaa atgccgatag aattatgtct
     4561 agttctgaac gtatgcgtga agcaatgaaa aataatgctg aatcgaataa taatcctgca
     4621 agcgcaattc agcaaaaagt ccaacaagat attgaagaac gtaaaaatgc tatgcacggt
     4681 caagctaagt ctgctgaaga attaattaat cagaagcgtc atgaagcgaa atacacgcct
     4741 gaagcaatga atcgcgagga aataatgtta aggaaacgtg tagaagggcg gacaggcgct
     4801 aatattgacg gaaaagaagc gttgaccaaa gaaagaattc aagaagctaa aaattcaaat
     4861 acaggattag aaaaattagt caaagaaaat ccacaaaatt ctacaagtag tcatggtggc
     4921 cgatcagtag atgtccgaga aaatattcaa ggttcactga atggtcatgt tggacggaat
     4981 gttgatgtaa gagagaattt acaaagttct tcaaatgctc aaggtactaa gacaattgat
     5041 gttcgagaaa atctgcaaag tagcagtaca agtcaaccaa aaacagtaga tgttcgagaa
     5101 aatgtacaaa attctacaag tagtcaaggg tttaaatcag tggatgtccg agagaatgtg
     5161 caaggtagca gtgcaagtca accaaaaaca gtagatgtcc gagaaaatgt acaaagttct
     5221 acaagtagtc aaggattcaa aacagtagat gttcgggaga acattcaaaa agatagtgga
     5281 gaaatgaaag aaaaaacaca aaaaatcaat atcgttgaag acagaaagtc agcgaaaaaa
     5341 tttgattcaa atcatgaaac agtgattatt gatagtgaaa tccgtgaaaa tgataaggga
     5401 tcaaaatcaa gacgaagatt cacttatgaa gacaatgagt tattcagaga tacacttaat
     5461 gatcctaatc cacttttcga taatttatta agaaataaaa gggggggatt gtcatgcaat
     5521 taattctaaa gattagtacg catgatttct tagaacttga cgaattatgt gaatcagtaa
     5581 agaacgcaac aaatgaaaaa atcacggtca ctaattatat tgaactgatg attcaagaag
     5641 aattaaagat gaaaaatgaa atagagagca atttcaaatg ttgctctcta gaaaaaaatg
     5701 tgaggggata atcaatggat gataaacaaa aaatgtacga aaaaaatcgc aaacatagtg
     5761 aggccttaaa ttttcgtgtc gataaaaaga cttatcttga actgacattg attgcaaaac
     5821 aaaggggaat ttctagagca gacgtttgcc gtgagcggtt aaagggactc aaatatgaac
     5881 cgccgttgtt agctgaagat
//
LOCUS       DAIGTA010000099         5856 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.105, whole genome shotgun sequence.
ACCESSION   DAIGTA010000099 DAIGTA010000000
VERSION     DAIGTA010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.105"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="NOB43_002585"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="NOB43_002585"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCI0983409.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="NOB43_002586"
     CDS             complement(1172..1867)
                     /locus_tag="NOB43_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HCI0983410.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="NOB43_002587"
     CDS             complement(1880..2596)
                     /locus_tag="NOB43_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HCI0983411.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="NOB43_002588"
     CDS             2926..3531
                     /locus_tag="NOB43_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HCI0983412.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLCEHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="NOB43_002589"
     CDS             3856..4179
                     /locus_tag="NOB43_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCI0983413.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="NOB43_002590"
     CDS             4361..5731
                     /locus_tag="NOB43_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCI0983414.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
BASE COUNT         1665 a         1154 c         1096 g         1941 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gtgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttt
//
LOCUS       DAIGTA010000100         5466 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.106, whole genome shotgun sequence.
ACCESSION   DAIGTA010000100 DAIGTA010000000
VERSION     DAIGTA010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.106"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            118..1107
                     /locus_tag="NOB43_002591"
     CDS             118..1107
                     /locus_tag="NOB43_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0983415.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="NOB43_002592"
     CDS             1089..1550
                     /locus_tag="NOB43_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI0983416.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLVLMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="NOB43_002593"
     CDS             1600..2064
                     /locus_tag="NOB43_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0983417.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="NOB43_002594"
     CDS             2078..2827
                     /locus_tag="NOB43_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0983418.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="NOB43_002595"
     CDS             2827..3657
                     /locus_tag="NOB43_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0983419.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="NOB43_002596"
     CDS             3657..4304
                     /locus_tag="NOB43_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0983420.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="NOB43_002597"
     CDS             complement(4402..5178)
                     /locus_tag="NOB43_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0983421.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5260..5403
                     /locus_tag="NOB43_002598"
                     /pseudo
     CDS             5260..5403
                     /locus_tag="NOB43_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1871 a          739 c          974 g         1882 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaat tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tatcgtaaag ttatataact ttataatacc tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtattaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattagtttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgtatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatggatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttcataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgactcca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgt taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtagat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaaataa aagattaaga tataaatata aatgaactag tctttgacta accaatgccc
     5281 gcttttgaaa gaaaacaaat tcattctgtt ttaagtaaaa atccttatgt taccactcat
     5341 tctgaagggg atgagcctta tcgctacttg gttgtggaac caagcgataa gacaatttta
     5401 taaattcaat attaattaaa ataaaaacaa acaaagtaga ttattttact ttgtttgttt
     5461 ttttat
//
LOCUS       DAIGTA010000101         5413 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.107, whole genome shotgun sequence.
ACCESSION   DAIGTA010000101 DAIGTA010000000
VERSION     DAIGTA010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.107"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(151..426)
                     /locus_tag="NOB43_002599"
     CDS             complement(151..426)
                     /locus_tag="NOB43_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HCI0983422.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(398..1351)
                     /locus_tag="NOB43_002600"
     CDS             complement(398..1351)
                     /locus_tag="NOB43_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0983423.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1963..3456
                     /locus_tag="NOB43_002601"
     CDS             1963..3456
                     /locus_tag="NOB43_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HCI0983424.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3591..3887
                     /locus_tag="NOB43_002602"
     CDS             3591..3887
                     /locus_tag="NOB43_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI0983425.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            3988..4839
                     /locus_tag="NOB43_002603"
     CDS             3988..4839
                     /locus_tag="NOB43_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983426.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            4860..5143
                     /locus_tag="NOB43_002604"
                     /pseudo
     CDS             4860..5143
                     /locus_tag="NOB43_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1863 a          834 c         1009 g         1707 t
ORIGIN      
        1 tttagtatag taaaaactag aaacaataaa atttgtgaat gttgtatacc cccaaacaat
       61 acacatattt tgaaggatta ggattaataa agctaaaaat atagtaagta tactaaatat
      121 atttactata tctagtatac ttactatatt ttaatctttt gatcgtctat tatatataat
      181 ccgttcctcg tcgtttaaag tatcaacata ggcgtccatt gcaagtttga ctatttcata
      241 cataggaata tcttttgcat aactaagatc ccgaatggtt tttagtacgg gaggatctac
      301 ttgaactggt tttctttctt tcgcagtgta ctttcgttcc cctaactcga cattaatatc
      361 atctttaatt gaaatatctt cagcaccaat tttcttctta tctttgttcg ttggtaataa
      421 tgccatttag tttaatctcc tttccaagag gtaggatatg attggccatt gagtcagcat
      481 atttaggtgt ataatcaaat ccttcaatat caccatgttg ttcatagtat tcaattcttt
      541 cttctaattc tgtaaagatg tctgcaaaaa tagcccacca tcttcgatct acataatcat
      601 ttaattggat accattctca ccatacattt ctaaccgatc cgagccttta acaatgcttt
      661 taaaaatgtt tgattcacca tacttatcaa ttgttttttg atagtttgcg tgttgagagg
      721 aacgtcgcac tgagaaaaga acaggcaaaa ttccaatgat ttgaagatga gactcttcaa
      781 aattcgtgac aatcggaact aaaactttat taataaaatc ttctgttcct tccattgcgt
      841 accgttttaa ttcttgcatt gcaataatat aatctgcagc agttaagaat gcacgaacca
      901 cattatctgt tgatggtggg cagtcgataa agatataatc gaaatttttt ctcaattctt
      961 ctaaaggttt aatgaaggcc aatgatctct tacgacgatc aggatatttt tcggacaagt
     1021 attcattaag ttcttcagat ccaggagagc cagccataat atataaatgt ggacttactt
     1081 gagtaatacc tgaaacccag tccccttttt tgattgctgc agacatggat cgatcaaagc
     1141 tagtaatttg atacgttgat ccaatgttgg aagtagtatt tctttgttgg tcataatcaa
     1201 ttagcaacac gtctttttca aaaagttgac tagaaacaat cgctaataaa tcattgtctg
     1261 tagtcttacc aatgccgcct tttctacctg taagcattac aacttttcct agtttatctg
     1321 atgttttaaa tgcagtccgt aagttttcca tagttccctc caatttccta tactaaatat
     1381 atttagtata cttcatatac ttaatatatt cgatatatct aatatactcc aaattgataa
     1441 gaattcagac tttataagga atatagtgga tatactaaat atatttgcta tattcagtat
     1501 atcagatata ttcaaaatgt caaaatatat ttgtgcgttt tgcgttgaca atttagagtg
     1561 aaaagaggta aacttaattc tatagaaacc acagataatt cactatttac aaagtagcaa
     1621 aagcagtggt actctttaaa cagaaaaatt acataaaaaa aagagacgga aataattgat
     1681 tttagcagaa tcaattattt ctgaatcaca tggttaggac atgtgttcac gctcgtctca
     1741 agaatatgta agtagctacc aactacttat attaaaagtt gatcggatac cttttccgat
     1801 tgcctttatt ctaccaaaaa aaggcgagca actcaacaga agaaagttta tttagtgtac
     1861 ttaaattaaa tattcttaaa cactgaagag agaacacata ctatggctga gattaaagct
     1921 aaactgtgtt ctctttttgt ttgagaaagg acgttacaat cgatgttgag cgaaatttat
     1981 tcagctattc ttaaaaacgg cttacgtaca tacaaatatc gaaacagcac catgaaacct
     2041 gcaggtcata ttgattccag taggagtggt gctatctttg cgtaccgtag caagcaatta
     2101 atgaatgttg ggcgtggtat ggtcattact tcggaagaag ctattttaga gaacgaaaag
     2161 aaactaacgc attggacacc taatacctat cgctttggta cttatgcgga tgattatcga
     2221 acagtggtta aaggtcattc tgagaaaaac ttaagtcaaa tcaacacatt tgtagttgat
     2281 atcgattcaa aagagaacca tcaaggcgaa attattttag cctgtttaga tcaagtgggc
     2341 tacatgccaa cgctaatttt agaatcagat catggttatc aagtttattt tgtactaaag
     2401 acaccaggct atgtcacaaa gaaaagcaat ttcaaggtga tcgatgtagc aaaaaaaatt
     2461 tcaaaaacaa ttcgtctaca gttggctgaa aaattgtccg gagtggatct aggatgtaac
     2521 cacttcggaa ttgctcgatt cccacaagaa aataatattg tttttaaaga aatgaactat
     2581 cagtattctt ttgctgactg gattcaatgg tcgatgaagc ttgaatcaga tcaaaaaaca
     2641 aaagaagatc gagaacgaaa actaattgtc tttcctgaga aaaaagaaat tcgtcaagta
     2701 gatgaaccgt ggttcgatat gttacttcat aaagcaaaca tcgtcggcgg agaaggacgt
     2761 cttggtcgaa ataatgtgat tttcacgctt tctttagctt attactcttc aggttatgca
     2821 ttggatactt gcgaatacaa tatgttcaca ttcaacgaac ggttacagga accgctatct
     2881 gaagcagaat tagtaaagat tgtacgtagt gcttattctg gtaattatca agcagcaagc
     2941 agagaattca ttattgaatt gtgccagcaa tgggtttcac caaccttaaa aaataatgat
     3001 ctgttcattc aacgacgtgg ctggtggaaa tttaaaaagc cacgagatca aagaaaatat
     3061 agtcataaaa atgaatggaa agaagatcta ttggcttatc taagcgaaaa aagtcttgct
     3121 agtgagcctt atttgaacct gtcaaaaaaa gaattggctt cacaactaac gatgcccaag
     3181 cgaacacttg ataagatctt aaatgagtta cgagaggaga ataaagtctt ctacaaggta
     3241 acacgaggaa gaaatggcgg aatgatcatt gcttcagtca aaacgttgtt cgcgagggtt
     3301 attcaactaa gtaaagaaaa gagactagat tattcaacaa ggatcacaga ggtatttgga
     3361 ctcaacgaga gcttagtaga agagacattt agacaattat caaccccctt gaaccctctt
     3421 aaagaagtga atctttttga agtagataca ggttgaaaaa taaaaggtgc aaattgccct
     3481 atacaatata tctatgatac ttctgtaggt gttgctccct ttgcctagct acgtgtaggt
     3541 ggtatactta taactgcgta tgcagtctta tgtatcatgg aggaagttgt atgtcgttaa
     3601 aaaattatgt ctattcacat cctgttaatg tgtttatcat tggtcgtttg ggattatctg
     3661 tggaagtgtt ctgtgagctt tatggtttta agcaggggac tttgtcttct tgggttacca
     3721 gggaaaaaac agttgcttct ttgccgattg agtttcttca tgggttgtcc ttagcttctg
     3781 gggagactat ggatcaggta tatgattgtt tgtgtgtgtt agagcaggag tatattgagt
     3841 ataaaatagc taacgagtta agaaaaagga agaagtatat ccagtagtag tttttattta
     3901 cttaaaaaat tggttcattg agcaacctat cgctgctaaa gtagcaaagg aaaacgttaa
     3961 aggaaagaat ttagggaaga aatcgaaatg aaatcggacg actggattga acacacctgg
     4021 cttcctctga aaagaaatag caaacgaaag aaattttggg tattgcaatt atggccatta
     4081 ggaaaacttt gtagttacgg ggcacgactt attcttgatt taaccgttta ctcgattgga
     4141 gtatttggaa cggcttatta cttgataaat gatcccaata ggattgcagc atcagacatt
     4201 tttacagtgc taatgacgtt gatttttgtc atgctattgt ctatttttac tcaattagtc
     4261 atgcaattta ccaggcaaaa attaacagca ggaaaacttt tcaaaagcct attcgattta
     4321 attgttgtaa atgcaattct agcgacttta ataaaacaaa ttgaacaatc tggaagaaca
     4381 acaaaaggag tgaaggattt tttattgacg tttattcact ttgtaaatgg acacatgtat
     4441 ttgtttgaag tgggtattat tctctttttt gtcgggtatg tatccacgaa acttattaaa
     4501 cgttcaattg aaaaagaaat tgaaattgac ctgattccga cacttcttgg ttatgagtac
     4561 aatgttgatt ttggaagata tgacgaattg atcaatacgg atatcgttca cacgagtatc
     4621 catgaatcta ctgttaaggg catcagatct attttaaaaa atggccagga aatgaaagca
     4681 atagatcgaa gaaaagagat ctacaatttt tatgaagtcg aagcaagcct acgatatggc
     4741 atcggaaaat tgtggttaga tggaagtaat attcgtcaaa acaaaccata cattttttgg
     4801 aacagtagtg atttagaact tccaatgaaa gataaataat tatggagaat cgtttgaaaa
     4861 tgattcctct atacaggatt gtgcttatag ttggcatgga gttaaaaacc ttaaagaagg
     4921 agcagttatt caaagtgaaa gaacgtcata atcagttact atgtagtaaa acgggtacga
     4981 tgaacattga ataccgaaca gaatatttag aattaacgaa tcaaactgat tttttgttga
     5041 ttcgaaagca acaagagcaa gaaaaaaatt aatggctact tatagccaat tgattgatga
     5101 atgggaacaa ttcaaggaat ctaaaattcc agaacgtctc taaaagcctt tatttgtaaa
     5161 gagcataagg aaacgtggga acacttttta aaaaaagtgt tccaataggc tgtgcctatt
     5221 acgtttctca aaaataaatg tgggaacaaa atatttaaaa ataggatagt gaaaggatag
     5281 tgaaggatag taaaaggagg gtagtaggat agcaaaaagg ataggctcct tttcgctatc
     5341 ctttttaaat tggaggaatt aatatggaag taagaataag aaatgtggat gagaaaatcg
     5401 taagagaaat tga
//
LOCUS       DAIGTA010000102         5359 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.109, whole genome shotgun sequence.
ACCESSION   DAIGTA010000102 DAIGTA010000000
VERSION     DAIGTA010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.109"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            25..696
                     /locus_tag="NOB43_002605"
     CDS             25..696
                     /locus_tag="NOB43_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0983427.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="NOB43_002606"
     CDS             755..1195
                     /locus_tag="NOB43_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983428.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="NOB43_002607"
     CDS             1207..1875
                     /locus_tag="NOB43_002607"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI0983429.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="NOB43_002608"
     CDS             1939..2562
                     /locus_tag="NOB43_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HCI0983430.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="NOB43_002609"
     CDS             2618..3004
                     /locus_tag="NOB43_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HCI0983431.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="NOB43_002610"
     CDS             3217..4608
                     /locus_tag="NOB43_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCI0983432.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1778 a          883 c         1124 g         1574 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagtc taatggtgat
     5221 aagtcaagat gaaatttaag attttcttta ttgagtaata tgttttgaag cgcacgaaac
     5281 tagacccgat caaaatcaaa tttttttcgg gttgattcaa ggatttgcgt caataacgga
     5341 ttgttatttc tctatcaca
//
LOCUS       DAIGTA010000103         5030 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.111, whole genome shotgun sequence.
ACCESSION   DAIGTA010000103 DAIGTA010000000
VERSION     DAIGTA010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.111"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(141..1085)
                     /locus_tag="NOB43_002611"
     CDS             complement(141..1085)
                     /locus_tag="NOB43_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HCI0983433.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDMD
                     KQVTFIEGDVSDSQLMERIMKEYQFAYIFHLAAVASVADSVERPVETHRVNFDSALLL
                     LELARKYQSNLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKAEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILSGMERYLKTEI"
     gene            complement(1219..2610)
                     /locus_tag="NOB43_002612"
     CDS             complement(1219..2610)
                     /locus_tag="NOB43_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HCI0983434.1"
                     /translation="MLNERFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFVINIFIQFS
                     FIALSGSRTTLVCLLITTFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAHAWAHVPHITEVKKDTSDSSGTTSSNKVDLKRPDTDSGDVSNLRFELWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKALRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            2736..3146
                     /gene="tagD"
                     /locus_tag="NOB43_002613"
     CDS             2736..3146
                     /gene="tagD"
                     /locus_tag="NOB43_002613"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HCI0983435.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGHFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            3322..3735
                     /locus_tag="NOB43_002614"
     CDS             3322..3735
                     /locus_tag="NOB43_002614"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983436.1"
                     /translation="MISISHSIKELFTIKDKNIEINSFQETFYKDKKAIVIEGPLVRT
                     FRHCLFCKESAKQIEKNGKKISMIILNRSGNKQTYLRLRKQHYHCQSCGKYFTAHTYL
                     VAPSCFISKQVHYTILEELTERQALKTIAKRCDFQ"
     gene            3892..4149
                     /locus_tag="NOB43_002615"
     CDS             3892..4149
                     /locus_tag="NOB43_002615"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983437.1"
                     /translation="MTFCPAGEKKDLIAYFMRFTRKAHMGVRYIVTDMNAPYFSLVKE
                     PFPNAQIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKCQRHL"
     gene            4236..>5030
                     /gene="istA"
                     /locus_tag="NOB43_002616"
     CDS             4236..>5030
                     /gene="istA"
                     /locus_tag="NOB43_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCI0983438.1"
                     /translation="MRKDIREGVMIYVINEIKPNYAALAKQYDCDYRTVKHAYEEAQV
                     KESKPPERKKRPSKLDPYREIIQDKIKDQCSAYSIFKFIEHKGFGGSYSLVKTYCRQI
                     KQAKVHKATVRVEHSPGLSAQVDWKEDMRLISNQGEIFEFNIFLYVLPYSKKKYVTLT
                     FDRKQDTLFECLDDAFYQTGGVPKEIWFDNMKTVVDHSRSQFSKPHFNKRFYAFSKDA
                     GFTPIACRPFRPQTKGCVEALARTVDRLRVYNHEFYDAVELCHLVNN"
BASE COUNT         1746 a          909 c          791 g         1584 t
ORIGIN      
        1 agttctcttt ttcatgtaaa atatttaatt atatatttcc taaataaaaa gtaaaacaag
       61 aattaaatag ttggttatac aactttaatt cttgttttac tttttagaat tatttatcca
      121 aagatgcaat cattttttca tcaaatttct gtctttaaat accgttccat tccgctcaat
      181 atatcaaatt taggctgata gcctaaagaa cgaatttttg aaatatccgc taaggaatca
      241 cgaatatccc ctgaacgctc cgcttcatat ttaagcgcta gctctgttcc taagatttga
      301 tcaattgaat ggatcaattc aagtagcgta gtgctttttc ctgtaccgac attgaattgc
      361 tgtcctaaag ctttttcttc cttggcaaca agtaaaagtg cttgtataac atcttctata
      421 taaacaaagt ctctagactg actcccatcg ccaaataaag taaattccgc tttttctcct
      481 gccaattgtt ttttgtaacg atccactaga atcgaaatga ctccgctata tggagagttt
      541 ggattttgat ttggaccata aacgttaaaa aatcggacag cactagtcgg aacatcatat
      601 aaatgacagt aatccaaaac atattgttct gctgcaaatt tatcgatagc atatggtgtt
      661 aatggacgga tgactgattc ttcttttttt ggcagtgttg gttcatcacc ataaactgca
      721 gctgatgaac taaatactaa tcgttttaaa ttagattgat atttccgtgc taactcaagc
      781 aataaaagcg cactgtcaaa atttacacga tgtgtttcta caggccgttc tacagaatct
      841 gccacactag ctacagcagc tagatgaaaa atataggcaa actgatattc tttcatgatt
      901 ctttccatca attgagaatc tgatacatcc ccctcaatga aagtcacttg tttatccata
      961 tccaagtttt ctttttttcc cattgataaa tcgtcaacta ctacgatttt gttttctttt
     1021 cccaaataat tcgctagcgt tgaaccgata aaaccagctc cgccagtaat caatatagtg
     1081 tccatcaaat tcactccaat tgcacatttt cgtatcaaat aatattagtt taccattttt
     1141 atattgtaaa aactataaaa tttgttgaag ttgggataac tagttttctt ttctactttc
     1201 atatacctaa aaatagtttc aattagttac tccttcttct ttagatatag ttttttggat
     1261 agaacccaga tatccccaaa aaataaatga acctatcgta ctaaccaaaa tgagttctgt
     1321 gataaataat gccgaaactg ctattgtaag aatcattaaa atagcaaaaa agtgcttatc
     1381 ttttactaga tttggttgtg tgaaacaata acgcaaggct ttaaagcatt ggataaataa
     1441 gaaggttaac aatgtcaata gacctaatcc tcctgtagca gccatcacta agaaaataaa
     1501 attatgagca gttaaagtat cttttcccat taatgtatat ggtagtttat catgtgcata
     1561 ttcaatatag tagcctggag aacctccgga tatcggctta ctcttgaata tttcaattgc
     1621 acttttccaa agttcaaacc ttaaattaga aacatccccg ctatcagtgt cagggcgttt
     1681 taaatcaact ttattgctgc tagttgttcc tgatgaatca gatgtatctt tttttacttc
     1741 tgtaatatgc ggaacatgtg cccatgcatg agcagttata tctgttacat aatacatcgc
     1801 aattatactt agcaatccta ctactaatgc agttagccat ctttttaaag tattagtttt
     1861 aagaaaacga ctactataac ttgtaaagaa actaaaaaca aaagttgtta ttaataaaca
     1921 aactaatgtg gtgcgtgaac ccgataaagc aataaacgag aattgaataa aaatattaat
     1981 tacaaaaaat attttaaata gaagatttaa atgcttgtaa gtgaccaaat aatatatagc
     2041 aataatgatg acgattaatg atataaccgc accaaaattt ggatctgtat atacaccaaa
     2101 taaacggttg cctaaccacc ctaaacgaac tgggtaatac ttatatttta ttggaatttt
     2161 tatgccatat tgaatgacaa accagtataa tgatactaaa ttagctaaaa accataccaa
     2221 tgaaagtatc caggtaaata ctttgaaaaa aaagttacta ctatagtctt tgccaaactg
     2281 ataaatcata aagaaaaaga ttaattgcca catgattaac ttaatatttt cgctatatcc
     2341 atattttaaa ttcattaaac tgcttactag catcgcgcca ataaaagcaa ttaatagcca
     2401 atcatatttt tttagatttt tttctctaaa tgcaataatt gcatctataa tgatcaagac
     2461 aactcccgct attccagcag gccaaaaaag taaagtatca tatctagtag gtaatagtaa
     2521 atacgggcct attgctcgta acattaaaat aaaaccaaaa taaataaaat accaaccttt
     2581 cacatatttt aaaaatcttt cattcaacat ttttcctcca tccacctatt tctcataaat
     2641 atttcttatc ctttttagga taaactggtc ctttcaattc taacaaaaaa atgctaaact
     2701 aacaatgtat attaatgaat ttcgagaggt gaaagatgaa aagagtaatt acttacggta
     2761 cctttgattt gcttcattac gggcatatca atttactgaa acgagcaaaa caatacggag
     2821 actatcttat tgttgccctt tctacagatg aattcaattg gaatgcgaaa caaaaaaaat
     2881 gttattttag ttatgaaaaa agaaaacagt tacttgaagc tattcgctac gttgatttag
     2941 ttattcctga agaaaattgg gaacaaaaag taaaagatat aaaagaatac catgcagatt
     3001 atttcgtgat gggcgatgat tgggctggac attttgatga acttgaacaa ctaacagatg
     3061 cacaagtgat ttatttacca agaacacctg agatctctac aactcaaata aagaacgaac
     3121 ttaattcttt aaatagtgat aaataatatt ttttaaacaa taaaagaaca atatatctgg
     3181 ataagacgta aaaaaatggc tctataattt ctaggactga tagaattttc tgtcggtcct
     3241 agattttttg taaaaaaaaa cagacataaa aaaattccga tagaatagag tcgtctaaaa
     3301 catcaatctg aaaggaagtt tttgatatcc atttctcatt ctatcaaaga gctcttcact
     3361 attaaagata aaaatattga aattaattct tttcaagaaa ctttttataa ggacaagaaa
     3421 gccatcgtaa tcgaaggtcc attagttcgc acttttagac attgtctatt ttgtaaagaa
     3481 tctgcaaagc agatcgagaa aaacggcaag aagatttcaa tgattatctt aaatcgcagt
     3541 gggaataaac aaacctattt gcgtcttaga aaacaacatt accactgcca atcatgcggg
     3601 aaatatttta ctgctcatac gtatcttgtc gctccttcat gttttatttc gaaacaagtt
     3661 cattacacga tattagaaga gttgaccgag cgtcaagcat taaagacaat tgcgaaacgt
     3721 tgtgattttc agtaacgaca gttcaacgga cattatctgc tctatcggca acgctgcgac
     3781 agaagctaga ctatttacct cattgtttac tattcgacga gtttcgctct ctttcaattt
     3841 tccatgggaa gttctccttt tcttgtatga attgagagac agggaagctc tttgacattt
     3901 tgtccagccg gagaaaaaaa agatttgatt gcttatttca tgcgttttac aagaaaagct
     3961 catatggggg ttcgatacat tgtcacagat atgaatgccc cttatttttc attagtcaaa
     4021 gaacccttcc caaatgcaca aatcatcatt gattgctttc acattgggca acacttgaac
     4081 aagtttttcg atcgtgttcg aaaacgtgtg atgaagcagt tgaatcaaaa atgtcaacgg
     4141 cacctttaaa atgtaggaaa acggcaattt aaaattgttg gtttacctac atttttgtat
     4201 gctcttctta tcccaaatga aatggaggct cagggatgag aaaagacata cgcgaaggag
     4261 tgatgatcta cgtgatcaat gaaatcaaac ccaattatgc tgcactagca aaacaatacg
     4321 actgcgacta ccgaacagtt aagcatgctt acgaagaagc ccaagttaaa gaatcaaaac
     4381 ctccagaacg taagaagcgt ccaagtaagt tagatcccta cagagaaatc atccaagaca
     4441 aaatcaaaga ccaatgcagt gcttacagca ttttcaagtt tattgagcac aaaggatttg
     4501 gaggaagcta cagtttagta aagacctatt gtcgccagat taagcaggcg aaagtacaca
     4561 aggcaaccgt ccgagtcgaa catagccctg ggctttctgc tcaggttgac tggaaggaag
     4621 atatgcgact aatcagtaat cagggcgaaa tttttgagtt caatatcttt ttgtacgtct
     4681 tgccatattc caagaaaaaa tatgtcacac taactttcga ccgaaaacaa gacacactct
     4741 ttgagtgctt agatgatgcg ttttatcaaa ccggtggcgt tcccaaagaa atctggttcg
     4801 ataatatgaa gacagtcgtt gaccattctc gtagtcagtt ttccaaaccg catttcaaca
     4861 aacgttttta tgctttcagt aaggatgccg gcttcacacc aattgcctgt cggccatttc
     4921 gtccgcaaac aaagggctgt gtcgaagctt tagccagaac tgttgaccgc ctacgggtct
     4981 ataatcatga attttatgat gccgttgagc tgtgtcattt agtgaataac
//
LOCUS       DAIGTA010000104         5017 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.112, whole genome shotgun sequence.
ACCESSION   DAIGTA010000104 DAIGTA010000000
VERSION     DAIGTA010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.112"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..863
                     /locus_tag="NOB43_002617"
     CDS             <1..863
                     /locus_tag="NOB43_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983439.1"
                     /translation="QGLQKKFGKFQALKDVSFTVNAGEVVGFIGPNGAGKSTTIRTLL
                     GIINRDEGDVQIFGKDVWKDSLEIHKRISYVPGDVALWGSLTGGEIIDLFIKLHGGGS
                     KAKRDYLIKRFELDPKKKAKGYSKGNRQKVGLIAALSVESDLYILDEPTSGLDPLMEA
                     VFQEEVEKIKNDGKAILLSSHILSEVERLADKVAIIRRGEVVETGTLDELRHLTRSTV
                     TLVTEGDIEKLATLSGVHDFVQKDGKATFSADNEAMNTILTEATKLGVTKIESVPPTL
                     EDLFMRHYEG"
     gene            887..2500
                     /locus_tag="NOB43_002618"
     CDS             887..2500
                     /locus_tag="NOB43_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI0983440.1"
                     /translation="MNEKFARWNVLFIQYVKRDWKKIIVWVLGLGLFSGAFVPAFEEI
                     AKGQGLLGMFETMQNPAMISMVGPTPIKIGTDYTLGAMYAQEMLLFCGLFAMIISALH
                     VVSHTRKEEELGLTELVRSFRVGRQANSLAVISEMLLINLLLGLLIGGLMMSFGVKTI
                     DAEGAFLFGGSIALAGIIGGVLALVMSQIMATSTGATGSTLSLIGLLYIVRAGTDVSN
                     LDLSMFNPMGWIYLTYPFTENNWLPLLFALIFSLVFTVLAFVLEEHRDMGAGYLPERE
                     GRATAKKSLLSVPGLFFKINKGVMIGWLIAFVVMGAAYGSIYGDMQVFLGGNELMKQM
                     FTQSGVSIEESFTATIMMVMIGLVTILPIAVVNKLFAEETRLHLSQLYVTKITRGQLY
                     WTTIFLAIFAGVVGIGLASAGLGGTAISAMKNESTMDLTDFLAAGYNFLPSILFYIGL
                     AALALGWLPKFGKVIYAYLGYSFALNYFGGILDLPDWFSKTAIQSWIPRLPMEKFDGT
                     IFAVITVISIVFLFVGYLGYKRRDMVEGA"
     gene            complement(2572..3084)
                     /locus_tag="NOB43_002619"
                     /pseudo
     CDS             complement(2572..3084)
                     /locus_tag="NOB43_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337518.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            3347..3463
                     /locus_tag="NOB43_002620"
     CDS             3347..3463
                     /locus_tag="NOB43_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta-toxin"
                     /protein_id="HCI0983441.1"
                     /translation="MVQNQHQETPEFKAIQQKLESLQPPTPPIPKTPKLPGI"
     gene            complement(3726..4463)
                     /gene="erm(B)"
                     /locus_tag="NOB43_002621"
     CDS             complement(3726..4463)
                     /gene="erm(B)"
                     /locus_tag="NOB43_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI0983442.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(4588..4671)
                     /locus_tag="NOB43_002622"
     CDS             complement(4588..4671)
                     /locus_tag="NOB43_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HCI0983443.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
BASE COUNT         1546 a          869 c          992 g         1610 t
ORIGIN      
        1 tacaaggctt gcaaaaaaaa tttggtaaat tccaggcgtt gaaagatgtc tcattcacag
       61 taaacgccgg tgaagttgtt ggttttatcg gaccaaatgg agcaggaaag tcaacgacga
      121 tccgtacact gctaggaatc atcaacagag acgaaggaga tgtccaaata ttcggaaaag
      181 atgtttggaa agatagtcta gaaatccata aacgaatttc gtatgttcct ggagatgttg
      241 ctctttgggg cagcctgact ggtggagaga tcattgatct atttatcaaa cttcatggcg
      301 gcgggagcaa agcaaagcgc gattatttaa tcaaacgatt tgaacttgat ccaaagaaaa
      361 aagccaaagg ttactctaaa ggaaatcgtc aaaaagtcgg tttgattgct gcactttcag
      421 ttgaatctga tctgtatatt ttagatgaac cgacttcagg actagatcca ttgatggaag
      481 cagtattcca agaagaagta gaaaaaatca aaaatgatgg caaagcgatt ctattatctt
      541 cacatatttt aagtgaagtt gaacgattag cagataaagt agcaatcatt cgacgtggag
      601 aagtagttga aacaggtaca ttagatgaat tgcgtcattt gactcgctca acagttacat
      661 tggtgacaga aggcgatatt gagaaacttg cgacgctctc tggcgtgcat gattttgttc
      721 aaaaagacgg caaagcaact ttttctgctg acaatgaagc gatgaatacg attctgaccg
      781 aggcaaccaa attaggtgtg acaaaaatcg aatctgtacc gccaacgctt gaagatctat
      841 tcatgcgtca ttacgaaggc tgattgtcgg aacggaggaa aagaaaatga atgaaaaatt
      901 tgcccgttgg aacgtattgt tcattcaata cgtgaaacgc gattggaaaa aaataattgt
      961 ttgggtttta ggtttgggtt tgttctcagg agcatttgta ccagcatttg aagagattgc
     1021 taaaggacaa ggtcttttag ggatgtttga aacgatgcaa aatccagcga tgatctcgat
     1081 ggttggacct acaccaatca aaataggtac ggattatact ttaggagcga tgtatgctca
     1141 agagatgttg ctgttttgcg gattgttcgc aatgattatc tcagcacttc atgtggtgag
     1201 ccacacgcga aaagaagaag aattaggttt gactgaattg gttcgctcat ttcgagtagg
     1261 acgacaagcc aattcattag ctgttatcag tgagatgctg ttgatcaatc ttttattagg
     1321 tcttttaatc ggcggactca tgatgagttt tggtgtaaaa acgattgatg ccgaaggagc
     1381 tttcttgttc ggaggatcaa ttgcattggc gggaattatc ggtggtgtat tggcacttgt
     1441 gatgtcgcag attatggcga cttctactgg agcaaccggc tcgacattaa gtcttatagg
     1501 acttttgtat atcgtgcgcg ctggaacaga tgtgtctaat cttgatttat caatgttcaa
     1561 tccaatggga tggatttact tgacctatcc tttcacagaa aataactggc taccattatt
     1621 atttgctttg atttttagtc ttgtttttac cgtacttgcg tttgtgttgg aagaacatcg
     1681 cgacatgggc gcaggttatc ttcctgaacg agaaggacgt gcgacggcga agaaatcact
     1741 actttctgta cctggtttgt ttttcaagat taataaagga gtaatgattg gttggctgat
     1801 cgcatttgtc gttatgggag ctgcgtatgg ctccatttat ggagacatgc aagtctttct
     1861 tggcggaaat gaactgatga aacaaatgtt cactcaatct ggcgtttcca ttgaagaatc
     1921 ctttacggca acgatcatga tggtaatgat tggattagtc acaatcttgc caatcgcggt
     1981 ggtcaataaa ttatttgcag aagaaacaag actgcatctg agtcaactgt atgtaacgaa
     2041 gattacgcga ggccaattat attggacaac gatattttta gctatttttg ctggagtcgt
     2101 aggtattggc ttagcatcag cgggattagg tggaacggcg atttctgcga tgaaaaatga
     2161 atcgactatg gatctgaccg atttcttagc tgctggatac aattttctcc cttccatctt
     2221 attttatatt ggtttggctg ctttagcgtt aggctggttg ccaaaatttg gaaaagtaat
     2281 ctatgcttat ctaggctatt cctttgcttt gaattatttc ggcggaatct tagatttgcc
     2341 ggattggttc tcaaaaactg caattcaaag ttggattcca cgcttaccga tggaaaaatt
     2401 tgatggaacg atttttgcag taattactgt tatcagtatc gtcttcttat ttgtcggcta
     2461 tttaggatac aaacgccgtg atatggtaga aggcgcttaa aaattgaatt tctaaaaaac
     2521 cgttcatatt tacgaaagtc gatttgagcg gtttttttat ggcttcaatt gtcaaattaa
     2581 gtgcaacgat tcattaaaaa atacttcata aggggttttc caatttagac atttccgtgg
     2641 tcgcgtgttt aatttattcg cccattcttg aatttgacta tcgaaaatac ctgaaatatc
     2701 ttcacctttg ggtgaatatt ctcgtaataa accattagta ttttcgtttg taccacgttg
     2761 ccatggagca tgtggatctg gaaaatacac tttagtgcca tttaattcta gcgttattcg
     2821 actatgttgg gagaattctt ttcctctatc gggtgtaacg gttttacatt tatcttctcc
     2881 tacatttctt agtagattga tcatacaatc aaccacattt ttagagattt tcttttcaac
     2941 cttaccaagt agggagaaac gagatctacg atcgactaga gttacaatac gagccctacc
     3001 tgttttaccg gctacagtat cagcttccca attaccaatc tcaaggcgct cattggcagc
     3061 agatggcctt tcatggatct tattgtatgc agatgatcca atgacagcta gggcaccacc
     3121 aaaacaagcg catgatattg ttgtcaaaaa cttaccgacc aatttagaaa cccttcataa
     3181 aacgggctta tttagcgata taaggcttta caatagagaa ggagtgaaac tctattcaag
     3241 cttagaaacg ccttccatta gtccgaaaga gaccttagaa agagaattaa atcgtaaagt
     3301 atcagggaaa gaaattcaac cgactttgga gagaatagag caaaaaatgg ttcaaaatca
     3361 acaccaagaa acccctgaat ttaaagcaat tcaacaaaaa ttggaaagct tgcagccacc
     3421 tacaccacca atacccaaaa cacctaaact tccaggtatt taaaccttaa aaaaggaaaa
     3481 gagtagttac caaaaaacgg taactactct ttttttataa aaacatttcc tcatgttggg
     3541 gtcccgagcg cctacgagga atttgtatcg ataagaaata gatttaaaaa tttcgctgtt
     3601 tttttctaat ttcattttga ggtgaattaa ttggtagtta ttagaggtgc cctataccta
     3661 ataatttatc tacattccct ttagtaacgt gtaactttcc aaatttacaa aagcgactca
     3721 tagaattatt tcctcccgtt aaataataga taactattaa aaatagacaa tacttgctca
     3781 taagtaacgg tacttaaatt gtttactttg gcgtgtttca ttgcttgatg aaactgattt
     3841 ttagtaaaca gttgacgata ttctcgattg acccattttg aaacaaagta cgtatatagc
     3901 ttccaatatt tatctggaac atctgtggta tggcgggtaa gttttattaa gacactgttt
     3961 acttttggtt taggatgaaa gcattccgct ggcagcttaa gcaattgctg aatcgagact
     4021 tgagtgtgca agagcaaccc tagtgttcgg tgaatatcca aggtacgctt gtagaatcct
     4081 tcttcaacaa tcagatagat gtcagacgca tggctttcaa aaaccacttt tttaataatt
     4141 tgtgtgctta aatggtaagg aatactccca acaattttat acctctgttt gttagggaat
     4201 tgaaactgta gaatatcttg gtgaattaaa gtgacacgag tattcagttt taatttttct
     4261 gacgataagt tgaatagatg actgtctaat tcaatagacg ttacctgttt acttatttta
     4321 gccagtttcg tcgttaaatg ccctttacct gttccaattt cgtaaacggt atcggtttct
     4381 tttaaattca attgttttat tatttggttg agtacttttt cactcgttaa aaagttttga
     4441 gaatatttta tatttttgtt catgtaatca ctcctgaagt gattacatct ataaacaaat
     4501 acagaagtta aacgatttgt ttgtaatttt agttatctgt ttaaaaagtc ataagattag
     4561 tcactggtag gaattaatct aacgtattta tttatctgcg taatcactgt ttttagtctg
     4621 tttcaaaaca gtagatgttt tatctacata acgcatttgg aataccaaca tgacgaatcc
     4681 ctccttctta attacaaatt tttagcatct aatttaactt caattcctat tatacaaaat
     4741 ttttaatgca ctatcaacac actcttaagt ttgcttctaa gtcttatttc cataacttta
     4801 gggttaacca tacgcaagac caatcactct cggacaatac tcatgatttt aatgataaaa
     4861 tccatgttaa acccatagat aagaaataca cctgcaataa ccgttacctg tttgtgccaa
     4921 tttaaaaatg caccactttt ttataattaa aacggttgaa aactgtacca ctaataactc
     4981 acaatagaga gatgtcaccg tcaagttaaa tgtacaa
//
LOCUS       DAIGTA010000105         4953 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.113, whole genome shotgun sequence.
ACCESSION   DAIGTA010000105 DAIGTA010000000
VERSION     DAIGTA010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.113"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(148..1110)
                     /locus_tag="NOB43_002623"
     CDS             complement(148..1110)
                     /locus_tag="NOB43_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0983444.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1112..2551)
                     /locus_tag="NOB43_002624"
     CDS             complement(1112..2551)
                     /locus_tag="NOB43_002624"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCI0983445.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNKNWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2736..4682
                     /locus_tag="NOB43_002625"
     CDS             2736..4682
                     /locus_tag="NOB43_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HCI0983446.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1603 a          824 c          803 g         1723 t
ORIGIN      
        1 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacaagttga
       61 caactccttt ttgtttacaa atcaattgga tatctacaaa ttgtattttc taacgaattt
      121 tatagacatt aaaaaattaa tttaacgtta aatacttcct ccagaaagta ttgagattgg
      181 taaaatataa tccttatttg tcttttcgcc tttaattttt ttcagaagaa tatcaacaat
      241 aagacttgca atttcatcaa ttggttgtct tattgttgtc aattgtggga aaaatttctc
      301 aataaaagag gtaccatcgt atccaataat ttttaaatct tctgggatat taagtttaag
      361 ttgatgagca attttcatag tgagaatggc tgttaaatca tcagaaacaa aaataccatc
      421 tggtttgtga tttataatag ttgactttat ttccatttca cgacggatag tagacagatt
      481 attaggaatt ttgaaaattt ttccatttgg attttgaaaa gaaaaaccta gtgcacgtaa
      541 ttctgtggga gaatccgtgt tatcatttcc tgtaatcata atggtatttt gacaaccatt
      601 tttttgtaaa gtcttagctg caagttttcc cccttcaaag ttatctgaag aaacaatgga
      661 aacattagga gctaaatttc tatcaaaagc aacaataggt gctctcacac gctcataatc
      721 agcaattcca agattatggc ttgatgagat tatgccatca acttggttgg cttcaagcat
      781 ttcaatgtat tctctctctt tagcaggatc attttgacta ttgcaaataa tcgttttata
      841 tccatgttta aataactcta tttcgagata ctcaatgagt tcagagtaaa agatattact
      901 aatattagga aaaataagac caataagctg aggtgacttt ccttgaagtc cacgtgctaa
      961 attatttggt ttataaccaa gagttttcat agcttcatga actttttgtt ttgttttttc
     1021 tgataaatat cccttattat taatgacgcg tgaaacggtt gttgggctaa ctccagctaa
     1081 ttcagcgaca tcagttaatt ttgctaccat tttaatattt taattcaaag tattttccag
     1141 taggttcgcc tgatttgatt tgaataccat tttggtgatt ttcagggaat acacgactag
     1201 taaacacttt ttctccttta ttaataaaaa tctcaatgat tgagttatct acaaaaatgt
     1261 tagcagttgt ttctttagta tcaattgagc attcacgaat cgtaccaaag tcagtggcat
     1321 attgaatgcc tgctttgctg cgatctaaaa taatttttcc ttctttggta tctacaatca
     1381 agctaagtcc atttccttta ctatcagaga aaagaagtaa ctccgatttc tgatttggag
     1441 gaaaagttag ttcaagctca taagtattat ttgtttctgc ttttgctgta aattgttcag
     1501 aactagcacg taatgatgta atagcttcta ctggatattg gtaaagttta ccatctttta
     1561 ttgaaagttc ttttacaaga ctcattgctc cctgataatc atacttatca gttggataat
     1621 cgatatcagg tagtccaatc caactgacaa tcagagcacg accatcagga gtattgaatc
     1681 cttgagtcgc atacgcttca aatccataat caagattttg aatttctgaa gcgcccacaa
     1741 gttttacttt ttctatgtca agcgattgac agatcttaaa agtattcgga tagatattcc
     1801 cataatttag ctcagattta tccaaccctt gaggacaata aatgagaaca ggttttttgt
     1861 ctacaaatac tagatttgga cactcaatca tgtattctga accagtgccg ccaaaatcaa
     1921 ggttgccaac ttcctcccat gtttccacgt tattgtcatc cgctttgtaa agtttgataa
     1981 agcctgattt ttctaaattt tgtgctccaa caatcgcata caattgtcct tcataattaa
     2041 acatttgtgg atcacgaaaa tgatcagtta catcagcagg tttatgaata agaacattct
     2101 cacctttcgt aatgttgtag tctttatcca tccatgctcc gatttgaagt gtatcacgtt
     2161 cccaattttt atttcgaacg tttcctgtat agagtaagaa tagattcccc tctatttcat
     2221 atgcagaacc ggaataagcg ccgtggctat ctcgttttgt gtctggaaga agttctgctc
     2281 ctgttacatg aaaatgaact aaatcatctg attcattgtg tacccattct ttcaacccat
     2341 gagcagctcc aaatggccaa ttttgataaa aaagcgtata ttttccgtta aaaaaagaaa
     2401 aaccattagg atcgtttaac aatcctgttt taggttcgat atgatagcta gcacgccaag
     2461 gtgatcgttt tacattatcc ttaattttat ccatctcatc tttagtccaa tcagaataag
     2521 cacgatatcg tatttctcga ggtaagttca tattttactc cttcaattta tctttttaca
     2581 actagtatgg taaacgtttt ccgttgaaaa atcaatcatt tcatttaaaa aaataaacta
     2641 tatgacaaac gtttgacata tttttaagat atgctaaaat aaatttgcat ttcagtgaac
     2701 cgttttcacg taaaaataaa aaaggagtga ttcgaatgaa ttacagtaaa gtagcttccg
     2761 acgtaataca agcggtcgga aaagataacc ttattgcagc tgcacactgc gctacacgtc
     2821 ttcgtctcgt actaaaagat gacacgaaag tgaatcaaaa agctttagac gaaaatccag
     2881 atgtgaaagg cacatttaaa attgatggac aatatcaagt gattatcggt gcaggtgatg
     2941 ttaatttcgt ttatgacgaa cttatcaaaa aaactggact ttcggaaatt tcaacagatg
     3001 atttaaaaca aattgctagt aaagataaaa aattcaaccc cattatggca ttaattaaat
     3061 tattatcaga tatttttgtt ccaattatac ctgcccttgt tgcaggtggt ttattaatgg
     3121 cattacaaaa ctttttaaca gctgctggac tttttggacc aaaatcaatt gaagaaatgt
     3181 atcctgcgat tgaaggtatt tcctcaatga tccaactgat gtccgctgca ccattcatgt
     3241 tcttaccaat tttagtaggt atttcagctg ctaaacgttt tggagcaaac caatttcttg
     3301 gtgctgcaat tggtatgatc atgacaacac cagatcttgg tggctcaact gaatattgga
     3361 atatttttgg ttatcatgtt tcacaaacaa actatgctta tcaagttatt ccagttttag
     3421 cagctgtttg gatattatct atattagaaa aattctttca taaaaaattg ccatcatcta
     3481 ttgactttac attcacgcca ttattatcag taatgattac tggatttttg actttcacag
     3541 ttattggccc tgtaatgtta ttgttgtcta atggaattac agacattatt gtttggctat
     3601 ataacactac tggatttatt ggaatgggta tttttggagg aacatattca cttatagtca
     3661 tgactggttt acatcaatca tttccagcta ttgaaactca attactttca gcgtggacaa
     3721 atggtatcgg acatggagac tttatctttg tagttgcatc tatggcaaac gttgctcaag
     3781 gtgctgcaac atttgccatt tggttcttaa ctaaaaattc taagacaaaa agtcttgctt
     3841 cctctgcggg tgtctcagca cttcttggaa ttacagagcc tgccttgttc ggagttaact
     3901 taaaataccg ctttccattc ttttgtgctt taattggttc aggaattgct acagcagtag
     3961 caggattact taaagtagtt gctgtttcac ttggttcagc aggtttcttg ggatttcttt
     4021 caattaatgc aacatctatt ccattttacg tattgtgtga attgattagc tttgtagttg
     4081 cttttgcaat tacttacttc tacggtaaaa caaaagctgc tggtatcttt aaagcagaag
     4141 aaattgctga acaaacacca gttaattctt caaaagtagc aacaacagat ccaatatcta
     4201 ctgatgttga atcaacacaa acaaaagttt catcagaaac aattgttagt cccatttctg
     4261 gtaaagtgat tagtctttct tcagtaaatg atccagtctt ttcatcagaa gctatgggaa
     4321 aagggattgc cattaaacca aatggaaaca cggtccattc tccagtagat ggtactattc
     4381 aactcacgtt tgaaactgga catgcttatg gtattaaatc aaataatggt gctgaagttc
     4441 taattcatat tggtattgat actgtatcaa tgggaggaaa aggatttaca caaaaagtta
     4501 ctactaatca aaaagttaga aaaggcgata ttcttggagc atttgaccgt tcaatgattg
     4561 agaaagaagg tcttgatgat acaacaatga ttattgtgac caatacttcg gattattcag
     4621 aagtaaatat agtagctgaa aatacagtca ctgagggtac tgatttactt gaaatcaaat
     4681 aaatatattt ccctgagtaa agatggaatt ttctttccaa aatcaaataa tatagattaa
     4741 tcaaatattt gagaataaca ttttatttaa tcttttcata tatcaattgt atgaaaaatt
     4801 attagaattt taaaaaatga taaaaattca aaaagaaaaa atagtagtta tttacttgtc
     4861 atgttactaa ataaaaaaat aatttaaata tgatatatag tcatttattt agtgatttca
     4921 ttctaaaata aagggagaaa tgtctatgct ata
//
LOCUS       DAIGTA010000106         4931 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.114, whole genome shotgun sequence.
ACCESSION   DAIGTA010000106 DAIGTA010000000
VERSION     DAIGTA010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.114"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            85..972
                     /locus_tag="NOB43_002626"
     CDS             85..972
                     /locus_tag="NOB43_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI0983447.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="NOB43_002627"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="NOB43_002627"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCI0983448.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="NOB43_002628"
     CDS             2274..2720
                     /locus_tag="NOB43_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0983449.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="NOB43_002629"
     CDS             2993..4345
                     /locus_tag="NOB43_002629"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HCI0983450.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="NOB43_002630"
     CDS             4516..4803
                     /locus_tag="NOB43_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983451.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1393 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt t
//
LOCUS       DAIGTA010000107         4804 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.115, whole genome shotgun sequence.
ACCESSION   DAIGTA010000107 DAIGTA010000000
VERSION     DAIGTA010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.115"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            6..863
                     /locus_tag="NOB43_002631"
     CDS             6..863
                     /locus_tag="NOB43_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0983452.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQRRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            885..1394
                     /locus_tag="NOB43_002632"
     CDS             885..1394
                     /locus_tag="NOB43_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0983453.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1431..1832
                     /locus_tag="NOB43_002633"
     CDS             1431..1832
                     /locus_tag="NOB43_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983454.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1944..2297
                     /locus_tag="NOB43_002634"
     CDS             1944..2297
                     /locus_tag="NOB43_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983455.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2331..2774
                     /locus_tag="NOB43_002635"
     CDS             2331..2774
                     /locus_tag="NOB43_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI0983456.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2791..3876
                     /gene="uxuA"
                     /locus_tag="NOB43_002636"
     CDS             2791..3876
                     /gene="uxuA"
                     /locus_tag="NOB43_002636"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI0983457.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3869..4582
                     /locus_tag="NOB43_002637"
     CDS             3869..4582
                     /locus_tag="NOB43_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0983458.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         1659 a          734 c         1084 g         1327 t
ORIGIN      
        1 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
       61 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
      121 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
      181 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
      241 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcga agagcagaag
      301 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
      361 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
      421 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
      481 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
      541 tcactatggg ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg
      601 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
      661 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
      721 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
      781 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
      841 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
      901 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
      961 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
     1021 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
     1081 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
     1141 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
     1201 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
     1261 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
     1321 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
     1381 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
     1441 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
     1501 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
     1561 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
     1621 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
     1681 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
     1741 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
     1801 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
     1861 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
     1921 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
     1981 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
     2041 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
     2101 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
     2161 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
     2221 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
     2281 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
     2341 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
     2401 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
     2461 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
     2521 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
     2581 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
     2641 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
     2701 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
     2761 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
     2821 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
     2881 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
     2941 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
     3001 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
     3061 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
     3121 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
     3181 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
     3241 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
     3301 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
     3361 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
     3421 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
     3481 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
     3541 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
     3601 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
     3661 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
     3721 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
     3781 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
     3841 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
     3901 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
     3961 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
     4021 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
     4081 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
     4141 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
     4201 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
     4261 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
     4321 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
     4381 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
     4441 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
     4501 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
     4561 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
     4621 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
     4681 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
     4741 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt
     4801 tttt
//
LOCUS       DAIGTA010000108         4788 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.116, whole genome shotgun sequence.
ACCESSION   DAIGTA010000108 DAIGTA010000000
VERSION     DAIGTA010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.116"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            564..989
                     /locus_tag="NOB43_002638"
     CDS             564..989
                     /locus_tag="NOB43_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983459.1"
                     /translation="MICKNKKKIIAIIASFSLIFSTACTVLLTNNANVEAASSSYKHN
                     HAGYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPGIISLVFGSAVSA
                     NNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
     gene            1019..1183
                     /locus_tag="NOB43_002639"
     CDS             1019..1183
                     /locus_tag="NOB43_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983460.1"
                     /translation="MKLTKIAVILAVIAGIILYFVLPANQFFLYFGIPAILIVNGVRI
                     FEQRKKCSST"
     gene            2141..3118
                     /locus_tag="NOB43_002640"
     CDS             2141..3118
                     /locus_tag="NOB43_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI0983461.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     YFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEEQNKALELVNQQIYSEKDPTSLQEKIKEQKRKLELL
                     QQLEELERKQNNLNKENKEINEQIPDNNSDIPPELKKGLLDNLQNLFKE"
     gene            3128..3625
                     /locus_tag="NOB43_002641"
     CDS             3128..3625
                     /locus_tag="NOB43_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983462.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNIIYLKKE
                     AVTTITKVLSGNEPGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQLALETQ
                     QKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQSKTEKKW
                     WQFWQ"
     gene            4001..4282
                     /locus_tag="NOB43_002642"
     CDS             4001..4282
                     /locus_tag="NOB43_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983463.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIEND
                     FDHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
     gene            4284..4700
                     /locus_tag="NOB43_002643"
     CDS             4284..4700
                     /locus_tag="NOB43_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983464.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPATNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1757 a          817 c          786 g         1428 t
ORIGIN      
        1 aaaaaaaaaa gaaaaatccg cttctgcgaa ttcttctttt ttcattttgg ggcgctgccc
       61 taatccctaa gtcccggtta ttcaatagca tggaaactca aagaataaga cgttccctgg
      121 aataaaaaaa aggctgctcg ttcgagcagt ccatacatag gaaaatgaaa aaacgacgtc
      181 ccttactgag aaacgctatt aaacttttaa caaatcctct aaaaaataac aagtctttaa
      241 aaagtgaccg gtaaaaatgc acaaagaact aaaaaagaga aattgcatca aatcaagcat
      301 tagaagctag taactagcta gaccaattga aaatcacaaa gtgagcgcct gtatctattg
      361 ctacaggcgc tacttggcat agtcgacatt atgtcaacaa gaatttaata taacatattt
      421 ttctagtttg ttataacaat gccactctaa caaaaatgta agcattatcc ttattaaaag
      481 ctccttgaca aggactatac cttttatttt atgattttta catagaaaac gttttctcta
      541 ttttttgttt agaggtgatt tttatgattt gcaagaacaa gaaaaaaatt attgctatta
      601 ttgctagttt ctctttgatt tttagtactg catgtactgt cttattaaca aataatgcta
      661 atgttgaagc tgcaagctct tcttacaaac ataatcatgc tggttataga tgttacaaaa
      721 tgagttatta tgtaagtcct tctaaatgca aacaattggc tcgccaaact aataaactta
      781 ataccgtctc agctattgca aactttattg gactatctgg attaacaccg gggattatat
      841 cattagtttt cggatcagca gttagtgcta ataatgtatt tgttacagcc gctagaagag
      901 gaaaaggcgt tcaattaaat tatattgccc attttagtaa taccactacc tataattata
      961 gttctaacca aaattatgtt ataaaataat taaaacttta aactaggagg aatgctttat
     1021 gaaattaaca aaaattgctg taattttagc tgttattgct ggcattattt tatattttgt
     1081 attgcctgct aatcaattct tcctttactt tggaatacct gcgattttaa tagtaaatgg
     1141 cgtaagaatc tttgaacaac gaaaaaaatg tagctctacc taatcgttac aaaacaacaa
     1201 tttcaccttc ggtgaaataa gcgaaacttt acaaaaagtg gctagcaaat gctagccttt
     1261 tttgtattgt agagcgtgaa ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1321 aagcggttat ttgcaccaaa tacctccgta tttggctagc aatccttcta aaaaatacac
     1381 ctatcgatca gagtcaaaac aaatcaattt tcgagtgagc gaatccgaat ttgcaaagct
     1441 gaagctttgc aaatgagtgt gccggcttcc gtaaaaatac atatggctat aatttgcgtt
     1501 ttaaggcgtt ttaaacgttc tggtatataa ttataccaaa acaactttaa aacgccttag
     1561 atctaatttt agaggtctta tagaacattt tagggttgtt agggcttgcc ctgaccgcct
     1621 gtaaggcgct ttgagaacaa gataagggtt ttatactaag actgtcttaa aacggcttaa
     1681 acaaacgctc agaacttttc aaaggagttc tttatgaact gtttttaagc aaaggagcct
     1741 ttaggcgact gcgcagtata atgtgagagc gtagcgatca cacattttta gtgaccgtag
     1801 ggagcgagtt tcccagttta gaaaaattcg cgaacttgtt tgaggaaaaa agcaggagtt
     1861 ttttaggcgg gaaattttgc ctcctctttt ataatctctt tttaaacctc tttttaaacc
     1921 tctttaccgt cggctgtatg cttactctcc caaggtgtgc agaatctttt gggggtcttt
     1981 ttgtctgttt ttaggggtct ttttgtctgt ttttaggggt ctttttgtct gtttttgggg
     2041 gtctttttgt ctgtttttag gggtctttaa ttaggggctt gacccctatt agaaagctct
     2101 ttataatttt gttaagtagt taatcttgaa ggaggatttt atggcaaatg aaattgtgaa
     2161 ataccaccat gaattaaata cgattccttt acgcaaattt acgtcagtag aaatgaattt
     2221 attcttctct atagtatcta gaatgcgtga cgtaggcgat aaaaaagtac aatttacatt
     2281 cgaacaatta aaagatttaa gcaattataa agcaactgca aatgttcgat tcatagatga
     2341 tttagaaaca acgtatgaca aattaatgga tttacgtttt ggtagaagaa gtgctgacgg
     2401 tttgcaacgt gaacgatttg ttttatttaa tcaatttaaa atcgatggaa aagctgatat
     2461 tccttttgct gaaatacaag tccatgagaa agccttaccc ttacttaata atcttgaaga
     2521 atgggttcga tattctctcc aacaattcaa tgaattagaa agcagttatt ccaaaaccat
     2581 gtttagatta ttaaaacaat acagaaccaa aggaattgcc tatttttcaa aagaagactt
     2641 tcatgaatta cttgatatcc ctaaaagtta tagagaaagt gatataaata aaaaaattat
     2701 aaagcctatt cgccaagaac taaccgcaat cttcaaaggt ctgacaatca aaaagaaata
     2761 cggaaaagga agaggaaaac ctgtcattgg ctatcaattc acgtttaaac ctgaaataaa
     2821 aaaagcagac gactttaata aacacgcacc aacaaaagaa gaacaaaata aagctttaga
     2881 actagttaat caacaaattt actctgaaaa agaccccact tcattacaag aaaaaatcaa
     2941 agaacagaaa cgaaaattag aacttttaca acaattagaa gagctagaaa gaaaacaaaa
     3001 taatctgaat aaagaaaata aggagattaa cgaacaaata ccagataaca attccgatat
     3061 tcccccagaa ttaaaaaaag gcttactaga taatcttcaa aacttattta aagaataagg
     3121 ggtttttatg acagataaaa ctatcaaaga attagcagat attctaggtg tttcaaaaga
     3181 taaagtgaag tatcaactga ggaaattacc tagtaatttt acctacaaaa aaggaaatat
     3241 tatctacctg aaaaaagaag cagtaacaac aattacaaag gttttatcag gtaatgagcc
     3301 gggtaactta cctagtgaat tacctgattc attacctacc gattacctac tcaaggagat
     3361 tgaaactaag aataatcata ttgaagaaaa agataggcaa attgaaaaac ttcaactagc
     3421 tttagaaaca caacaaaaat tactcgacca gcaacaacaa ctcaccctgc aagccaacca
     3481 acaaatcgag aaactgcagg aacaactaca gttgacttat acggaagaat cttcggaaaa
     3541 taaatcaacg actctttctg aagaaacaga atcgatagaa aaacaatcaa agacggagaa
     3601 aaaatggtgg caattctggc aataaaacca gcaatttaaa ttaataaaaa ttgctggttt
     3661 tattcttctt tttgcttttg cgagcagagc aacatgggcc catgttgcga tattttggtg
     3721 gcgccccaat ccccgttttt tcgttgaatc ttactcggac tgcactcgtt ttacagctga
     3781 tttttctgaa ttttgaaaga gcataaggaa acgtggtatc actttcttac gaaaggtgct
     3841 agataagctg tgcctatcac gtttctcaga aaaaaatttg ctatcacttt tttgccattg
     3901 tggctaggct atgtatagtg ttttggcgaa aaatagctat acaaatacta tatttgtatg
     3961 atatacataa attatatact gatacgaaag gaaaatttcc atggacattt tagttcgaaa
     4021 tatcaatccc aaaattatta caagaataga taaacgttgt caggaactaa caaccaaaac
     4081 gggcaaaaaa tggagtcgaa atcaatacct aaaaatttta atcgaaaacg attttgacca
     4141 cgaacttatg aattacaaaa aagatcaatt cgatttatta ttcgaaaaat ttattgccat
     4201 tcaagcagaa aatacgaaca tactaaatga ctatgttcac acaaacaacc aactcattga
     4261 aacacttatc ggaggaatat aacatgagaa aaacttctgt tcaaaaacac gtaacccttt
     4321 atcccagtca cgttgacgtt ttagattcca tcatcgaaaa aaatccagac gtcaacaatt
     4381 attcagaagc cattcgcttt ttatgtatga gttatgaacc tgctaccaat acaaccacaa
     4441 ccagtaacca agcaaaactc aatgccatgg gaaaagaaat ttctatcatg acagaaatca
     4501 tggcagaatt tgctgattta tatctaaaag atactggtgt tcttatcggt acaaattcta
     4561 aagtatatca agaagtgaaa gaaaaaattg aaaatcaact caatccttcc cgacgaaatc
     4621 aacccaaaaa tcgtcaaaaa gaaaccaatc aaacctttac ttctggaaat tttgacccaa
     4681 caaactttct aaaaagataa aaaaagaaac cgaaaaataa aaaaattcct cgatttcttt
     4741 ttagggatcg gtcttccagc aagatttgca agttggtacc aacttgcg
//
LOCUS       DAIGTA010000109         4754 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.117, whole genome shotgun sequence.
ACCESSION   DAIGTA010000109 DAIGTA010000000
VERSION     DAIGTA010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.117"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            154..384
                     /locus_tag="NOB43_002644"
     CDS             154..384
                     /locus_tag="NOB43_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HCI0983465.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            481..1782
                     /gene="murA"
                     /locus_tag="NOB43_002645"
     CDS             481..1782
                     /gene="murA"
                     /locus_tag="NOB43_002645"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI0983466.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1795..1971
                     /locus_tag="NOB43_002646"
     CDS             1795..1971
                     /locus_tag="NOB43_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI0983467.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2106..2402
                     /gene="yidD"
                     /locus_tag="NOB43_002647"
     CDS             2106..2402
                     /gene="yidD"
                     /locus_tag="NOB43_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCI0983468.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2586..3053
                     /locus_tag="NOB43_002648"
     CDS             2586..3053
                     /locus_tag="NOB43_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0983469.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3138..4022
                     /locus_tag="NOB43_002649"
     CDS             3138..4022
                     /locus_tag="NOB43_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0983470.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4136..4372
                     /locus_tag="NOB43_002650"
     CDS             4136..4372
                     /locus_tag="NOB43_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HCI0983471.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4460..4540
                     /locus_tag="NOB43_002651"
     tRNA            4460..4540
                     /locus_tag="NOB43_002651"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4494..4496,aa:Tyr,seq:gta)
     gene            4547..4618
                     /locus_tag="NOB43_002652"
     tRNA            4547..4618
                     /locus_tag="NOB43_002652"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4579..4581,aa:Gln,seq:ttg)
BASE COUNT         1599 a          741 c         1040 g         1374 t
ORIGIN      
        1 cagtcccttt ttttgcatat ttttagcatt tatttcctaa aaaatgtaag gggattccta
       61 tatttttaag tatacttgtt tttcctttta tacattttat ggtattatca ttttattagt
      121 tattataaaa caatcgttag aaaggacgtc attatgcaag tatacggaat tgatgcggtg
      181 cttcgaatcg tgagtcattt ggcgtttatc tacttagcct tctggtcttt acgttcgtta
      241 cgcattgaaa cttttttcag accaatgcat aatacgcaaa ttagaatggc aatcgtactt
      301 ttttcaattt ttttagggta cactgcaagt aattttttct tagaagttat cgctttatgc
      361 cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta ctattttaaa agcaaggatg
      421 ttataataga aaagattttg agtaagtgta tgctcattgg aattttttgg agggaacaac
      481 atggaagaga tcatcgtaag aggtggcaat caattaaatg gaacagtaag aattgaagga
      541 gctaaaaatg ctgttttgcc tattttagct gctagtttgt tagcagaaga aggtattacg
      601 acattagaca acgttccgat tctttctgat gtcttcacta tgaatcaagt gattcgtcac
      661 ttaaacgtag atgtagattt tgatgaacaa aagaatcaag taacaatcga tgcttcaaga
      721 caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa tgcgtgcttc aatcgttgtg
      781 atgggtccgc tacttgccag aaatggacat gcaaaagtag ctatgcctgg tggatgtgcg
      841 attggtaaac gaccaatcga tttgcattta aaaggatttc aagctttagg agcaaaaatt
      901 attcaaaaaa acggctatat cgaagcaatt gcggatgaat tgatcggtaa cacgatttat
      961 ttagatttcc ctagtgtagg tgctactcaa aatatcatga tggctgccgt aaaagcaaaa
     1021 ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa tcgttgattt agcaaacatt
     1081 ttgaataaaa tgggcgctca agtctatgga gctggtactg aaacaatgcg tattgaaggc
     1141 gtggatcatt tacatgcagt caaccactca atcgtacaag atcgtatcga agcaggtacc
     1201 tttatggttg ctgctgcaat gacacaaggc aatgtgctga ttgcagatgc tatctctgaa
     1261 cataaccgcc cattgatttc taaattgatc gaaatgggtg cagaaatcat tgaagaagaa
     1321 ggcggagtcc gtgtcatcgg accaaaacat atcttaccta cagatgtaaa aacgatgcct
     1381 catcctggtt tccctacaga tatgcaagct caaatgacag ctatccaatt agttgcagaa
     1441 ggtacaagtg tagtgactga aacagtgttt gaaaatcgtt tccaacattt agaagagatg
     1501 cgccgtatga acgctcatgt caaaatcgac ggaaatgtag caatcatgga tggaaaccat
     1561 gaattgcaag gtgcagaagt atatgcaaca gacttgcggg cagcagcagc attagtttta
     1621 gctggcttga aagcaaatgg aatcacacgt gtgcgtaact tgaattatct agaccgtgga
     1681 tattataatt tccatatcaa actacagcaa ttaggtgcag acgttgaacg tgtagacatg
     1741 gatcaaactt ctgctgaaaa aacagcacaa acgattgctt aaggaagtgg ctgaatgagt
     1801 aaccaacgat atatcttatt aactttgata aagattttag tggtgatctt attgcttatc
     1861 cttctttttg tggccggaac gatgatcgga tatggtgtca tcggtggcgg caatccattt
     1921 aaagtattcc agccaagttt gtggattcat attcgagact tttttcattg ataaataaga
     1981 atcacagtgg ttctagtcga tatgaagtga gccatgaagc agaacatgac aaaagaaaac
     2041 agaagggaac gttgacgtta gtcgcgatcc ctttttttag taaaagaaaa gaaggaatct
     2101 aattgatgaa gaagatattg atttatttag ttagaggata tcagcgcttt atttcgcctg
     2161 catttccacc tagctgccgt tattacccaa cctgttccaa ttatatgata aaagcaattc
     2221 aaacccatgg tgcactaaaa gggacggtaa tggggactgc acggatctta cgctgtcatc
     2281 cttttgtcaa aggcggtatc gattatgtac cattgacatt ccaattaacg cgaaataaga
     2341 aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa tacgagtagc actgagcgat
     2401 aaagaaacaa tttggaaaat agcttcttat attttgcaaa attgtgagtt attgccgaag
     2461 tgttggattt tgaacaccgt caaaaaaagg ttgtgaaaaa tacgggtagc actgagcgat
     2521 aaagaaaaag aggaaaatta ttgtcaaagt aacaactccg caactactta tatgggggac
     2581 aaaaaatgat cgaagaacta aacaagaaag atttaccatg gtccttgtta ttagatgcag
     2641 atcctgataa agaaaaagtt caagtatatg tttccagagg gagtggctgg atatggaaag
     2701 aaaaagaaaa aacaataggt gtactgatct atgtggcaag ggaaaaagaa tacgaaatcg
     2761 tcaatgtagc agtagcccca acgtatcaag gaaaggggat tggcggaaaa ttacttgaga
     2821 cagcttttca gaagctttca caactcgctt ccagtcaaac tcagatcatc atacgaaccg
     2881 gcagtactag cagtgcggcg ttacatctct atcaaaaaat gggctatgtg gagattggtc
     2941 gagtcaaaga ctattttatc catcattact ctgagcccat ttttgaaaat ggagatcaat
     3001 taagggatca agtaatttta gcaattcact tacctaaaaa tagctttaac taataaactt
     3061 tcaattcgag aaaatgcttt caaatgctaa atagatacat tacaatagct ttagcaaaca
     3121 aaaaggagaa tatttttatg ggaatattag tttttgattt tggtggatcg gctgtcaaat
     3181 atggttgttg ggatggcaaa gagattaaag gtaagggaca atttgcaacg cctgaatctt
     3241 gggaagaaat gaaagcgcaa ttatttcaag tttataaaaa aatactcgtt tcttttgaag
     3301 tcgaaggaat tggaatcagc tctcctggag tagtgaataa tgagaaacag gtgattgagg
     3361 gaatcagtgc gattccttat attcatggat ttaatatttt ccgagatttg gaaactctgt
     3421 ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc cggaatggct gaattttatg
     3481 aaggtgctgc ccgtgattat caagatgttg cttttgttgt ggcaggaact gggattggcg
     3541 gggcgttgtt cacgaaagga caaatcaata aaggggcaca tctttatggt ggagaatttg
     3601 ggttgatgtt cttaaatggc gataagacat tcagtaaact tggtacagcg gtacagatgg
     3661 cttggcgtta ttgtgaacgc aaaggtctcg ataaaaattc ttataccgga aaagatgtct
     3721 ttgaattagc agaaactgga gatgcaatag caaaagaaga agttgagagt ttttatacgt
     3781 atcttacaaa gggattattc agtattcaat tttcgtttga tccagaagtg atcgtattag
     3841 gcggcggtgt ttctgcaaaa gaagggctca ttgatgagat caaaagccga atgaagaagc
     3901 tgacagaaca attcgatctg catgatttcg aaccgcagat tttattatgt gaatacagaa
     3961 acgatgctaa tcttgtaggt gcagcagcaa actatctcgc tgtacgtcaa ggggagaatt
     4021 aagagcttta gagaaggtgc agcttgcata aaagaagtga atgaaatgaa taggagattt
     4081 ttacctaagg aatgttttat ttgctgcagt atgataaaat atctgagagg tgaaaatgat
     4141 gtcaaaaaaa aataaagatg ttgaagtgcg tatagaagaa gtgaaaaaag atatcaaagg
     4201 taagaattat gaagtcactc agttatttat agggaaaaaa atgattggtg agatcttagc
     4261 ctatgggcca aaagaatatg aaattttctt tggtgaagaa gattttggaa aagaaaaaag
     4321 tcttgaaaat gcgatagaaa cagtgattcg acactggaat ctgcacgaat aaaaaaatat
     4381 caaaaaaact ttcaataaag ggttgcaaaa atctggaaaa ttaggtatta taactaagtc
     4441 aggttgatac aaacctttcg gaggagtagc gaagtggcta aacgcgacgg actgtaaatc
     4501 cgttccttag ggttcagtgg ttcgaatcca ctctcctcca tttcattggg gtatagccaa
     4561 gcggtaaggc aagggacttt gactccctca tgcgttggtt cgaatccagc taccccagta
     4621 taccacaatc gtaagctctc gttagttcga gagctctttt ttttgctttg ctaccttgtt
     4681 ccttgaagat tctgctgatt taagatagag ttaagttaac tacaagaatt ggagggatcc
     4741 acatgaaatg gaaa
//
LOCUS       DAIGTA010000110         4627 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.118, whole genome shotgun sequence.
ACCESSION   DAIGTA010000110 DAIGTA010000000
VERSION     DAIGTA010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.118"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..183
                     /locus_tag="NOB43_002653"
     CDS             <1..183
                     /locus_tag="NOB43_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI0983472.1"
                     /translation="QRKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLS
                     RTQRRFEGTLRYSLGY"
     gene            270..1124
                     /locus_tag="NOB43_002654"
     CDS             270..1124
                     /locus_tag="NOB43_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0983473.1"
                     /translation="MENSLYLVKEPNTHLRDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINEQKYYLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGELVEYY
                     LKEIGVGKENLTFKVENLNSFKGIIFETLSYDQDNLISELSRQTQVYKFLELLLNSAS
                     YLKEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKSDMGISI
                     KEYISEIKLSIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGAYRKRRL
                     GLGIINGE"
     gene            1221..3470
                     /locus_tag="NOB43_002655"
     CDS             1221..3470
                     /locus_tag="NOB43_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI0983474.1"
                     /translation="MYKNNEMNIIYRSENQQFHLFNQEISYIFKISDDGKLLHLYYGE
                     NLPDNDYTHLIEMHHRPMTTYRKENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLTDFIYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3473..>4627
                     /locus_tag="NOB43_002656"
     CDS             3473..>4627
                     /locus_tag="NOB43_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0983475.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1624 a          661 c          850 g         1492 t
ORIGIN      
        1 caaagaaaaa cagttgagac tgttttttct tccttagaaa aattaggttg tcaaaatttc
       61 aactcacgtt ctgttaaagg gctagagagt agatttgaaa gcatattact ggcttacagt
      121 gttctattaa gtcgaacaca acgacgtttt gaaggaactt tgagatattc tttaggatat
      181 taaaattaac tagcaccacg ggtgatatta tgtaataata taaacatgat gaaacaaaaa
      241 ttatccaaat ctaacttagg aggactaata tggaaaattc tctatattta gtgaaagagc
      301 ctaataccca tttgagagat tgttacttta atttttgtgg atactcaaaa acagaaccta
      361 gacatagttt tggaccagct attcgagaac agtacttaat acacatagtc ttagaaggtg
      421 aaggttatta ttcaattaat gaacaaaaat actatctgaa aaaaggacaa ggttttgtga
      481 ttccaccagg agtatctact ttctatcaag cagatgaaaa aaatccttgg tcgtatgtat
      541 ggttgggatt aagtggagaa cttgtagaat actatctaaa agaaatcggt gttggaaagg
      601 agaatcttac ctttaaagtc gaaaacttaa attcttttaa aggaataatc tttgaaactt
      661 tatcttatga tcaggataat ctaattagtg aattatccag acaaacacaa gtttataaat
      721 ttttagaact cctcttgaac tcagcgagtt atttgaagga agggataatt actaaaaaga
      781 tgaatccttt tgttcgtcaa acaattgaaa taatacgtga gaatgcgtat caaaaattat
      841 ctgttaaaga tattgctgtc agtctatcga tacacgaaaa ttatttatca cgattgttta
      901 agagtgatat gggaatatca ataaaagagt atatcagtga aattaagctt tcgattgcaa
      961 atgacctact atcatcaact gaatattcaa ttcagcaaat cagtgataag ataggattct
     1021 caacagttca atctttttct aaagctttca agaaggccaa tggtgtttca cccggggcgt
     1081 atcgaaaacg taggttaggt ctaggaatca ttaatggtga ataaactaaa catttgattt
     1141 tgataaatat tcgttacttt aaacgcttac tatttatgta agcgtttttt ataatgcaat
     1201 aaagaagtgg aggagagcgt atgtataaga ataatgaaat gaatattatt tatcgatcag
     1261 aaaatcaaca atttcatttg tttaatcagg agataagtta catttttaaa atatcggatg
     1321 atggtaaatt actgcattta tattatggtg agaacttacc agacaacgat tatactcatc
     1381 taattgagat gcaccatcga cctatgacta cttatagaaa ggaaaacgat ttattatact
     1441 ccctagagca cttgaaacaa gaatttcctg aatatggtac aacagatttt agacatcctg
     1501 ccatttcact actacagaaa aatggctctc gtctaacaga ttttatctat caagggtacg
     1561 aagtggaaga aggaaaacca aaattagaag gtttacctgc tacctatgtt gataataatg
     1621 atgaaagcaa aacattgaaa gtttatattt tagattcagt tacaaatgtt caagtagaat
     1681 tattatatac aatttataga gattatcctg ttattactcg tagcgcgcga gttatgaata
     1741 aaggaaaaga tattcaaata atcgagaata ttagcagttt atcattggat ttacccgatg
     1801 caaattatga atggcaacaa ttatctggtg cttggggtag agaaagaact attaagtcgc
     1861 gtactttaca acaaggaatt caatcaatcg aatctactcg aggtatttca agccatcagc
     1921 ataacccatt tgttacttta aaaagaaaaa atactgatga aaatcaagga gaagctattg
     1981 gtgcagcact agtttactca ggaaacttct taattcaagc agaagtagat acatgggatg
     2041 ttactagact acaagttggc atcaatccat ttggatttaa ttggaaactc aatccaggag
     2101 aaatatttac agcaccagaa gcgattctgg tttattcaag taagggttta aatgccatga
     2161 gtcaaacttt tcatcaacta tttagaaaac gcttagctcg tggtaagtgg cgagaaaaag
     2221 accgtcctgt cttaattaat aattgggaag caacatattt tgattttgac gaagaaaagt
     2281 tggtaaatat tgctaaaaaa gcatttgatg ttggtattga attatttgta ttagatgatg
     2341 gctggtttgg agaaagagaa aacgattgtg caggattagg agattggcat gtaaatccta
     2401 aaagactacc tagaggaatc ggcagccttt cagaaaaaat tcgtagtttt ggtatgaaat
     2461 ttggtttatg gtttgaacct gaaatggtga ataaggatag tgagttatat cgcacacatc
     2521 cgaattggat tatttctaca cctaatcgaa aacctaatca tggtaggaac caatatgtat
     2581 taaattttgg gttagatgag gttgttgaaa atattttcga tcaaatgtgt aaaatcattg
     2641 atgaatcaaa cttagattac attaagtggg atatgaatcg tccattgact gatgtatttg
     2701 acagtcactt gtcagcagat caacaaggag aagtattcca cagatatgta ctaggcgtat
     2761 atcgcttata tgaaaaactt ataacaaaat atcctaacat actatttgag tcttgttcat
     2821 caggtggtgg gcgctttgat cctggaatgc ttcactatgc acctcaagct tgggctagtg
     2881 atgattcaga tgcaattgaa aggttaaaaa ttcaatatgg aactagtatg ctgtatcctc
     2941 tttcgtctat tggtgctcat gtatcaattg ttccaaatca tcaaacaaac cgtataacac
     3001 ctataaaaac tagaggaaat gtagcttttt ttggtgcatt tggatatgag cttgacttaa
     3061 atgaattaag tgaaggcgat ttgaggattg taaaagaaca aattgccttt tataaaaaat
     3121 atagaaccat aattcataat ggtacttttt atagactatt atcaccattc gatgatgata
     3181 atcaaaccgc gtggatggtt gttagtcatg ataagaaaac ggctattgtt gctcattata
     3241 aaacattaaa tgaggtaaat gctccttacc gccgactgaa attaaaaggg ttagataatg
     3301 acggacttta taatgtagga caaaatagtt tgcgatctgg aatggaattg atgagagcag
     3361 gactagtctg ttcagatgca tctagtggac aaataaatga tcagaatcga cgcccagaaa
     3421 catttgattt tgattccaag atttgggtta taacacagga ggaaaagtag agatgaataa
     3481 ccaaaaaagc ttacttcaaa aaggagcaat cttaagtatt tcactaatgt taacaagctc
     3541 tcaagcaatt aatggtgtta ttccacaaat gaaacagtct ttggggatat cacaaagtca
     3601 aagtgaactt ttaggaactg caccaagtat aactgttatt ttgtttatct tattatctag
     3661 ttactttgcc aaaagaatag gaatgaaaaa gacaataatt ttaggtttat tattagctgg
     3721 tataggagga attattccag tatttacagc taccttccaa accgttctta ttagtcgagt
     3781 aatattaggt gccggtttag gagtatataa ttcattggct gtgacatata tcagctcttt
     3841 atactctggc aatactagag caacgctatt aggtattaga aattcaatgg aagctttagg
     3901 tcagacaatc cttatttttc ttgctggagt tttagtgaac attaattgga cggcttcgtt
     3961 tttagtctat gcaattgcgt ttcctgtagc tctcttattc gcgctaaaag ttcctgaaat
     4021 tagagatgaa aatagtgaca tacctgaaaa tcatgtaaaa gaaaagatga atccaatggt
     4081 ttttgcccta gttctatttg caatcttact cgtaatgaat agtattgcta tttctgtacg
     4141 atttgcatca attgcaactg aaattaaagg ggtaaacttt aatgctagta actatttagc
     4201 tctaatgcct atcttaggaa tactagcagg atttatgttt ggaccaataa ataagtggat
     4261 aggaaaagga accctatact tgggaattat attctttata atttcaaatt tgttaattgc
     4321 tgtgtcaaac ggtaatatga cgttcctgct aacgggttta tttttatcaa gtataacagg
     4381 atcatggtgc ttcccattta tctttagtaa cttagataaa gtcactacaa agaatacaat
     4441 taattttgct acttcattga tttttattgg ctgtaatatt ggtaatttta tagctcctat
     4501 tgctatgcaa ttagcacaat ttctaacaag aagtacaaat ttgactgctc cattttttgt
     4561 attcgcagga atatttattg tgatcctatt tgtaacattt tttgcgacaa ataaaaaaaa
     4621 tactaga
//
LOCUS       DAIGTA010000111         4528 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.119, whole genome shotgun sequence.
ACCESSION   DAIGTA010000111 DAIGTA010000000
VERSION     DAIGTA010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.119"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..437)
                     /locus_tag="NOB43_002657"
     CDS             complement(<1..437)
                     /locus_tag="NOB43_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0983476.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAVRIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVY"
     gene            751..1173
                     /locus_tag="NOB43_002658"
     CDS             751..1173
                     /locus_tag="NOB43_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983477.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1183..1386
                     /locus_tag="NOB43_002659"
     CDS             1183..1386
                     /locus_tag="NOB43_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983478.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            1716..2333
                     /locus_tag="NOB43_002660"
                     /pseudo
     CDS             1716..2333
                     /locus_tag="NOB43_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            2507..2716
                     /locus_tag="NOB43_002661"
     CDS             2507..2716
                     /locus_tag="NOB43_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983479.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            2923..3123
                     /locus_tag="NOB43_002662"
                     /pseudo
     CDS             2923..3123
                     /locus_tag="NOB43_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3223..4524)
                     /locus_tag="NOB43_002663"
     CDS             complement(3223..4524)
                     /locus_tag="NOB43_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0983480.1"
                     /translation="MENSAFIMKLNDILSPIAAKIGNQRHLKAISSGMMFGLPFIVIG
                     SFFLIFANPPINIDKYNPDTANIFMKFMASWKDFAVANYDLITAPYNLTMGIIGFISV
                     FGIAFSLANEYKINPSMNGMVASVIYLMVCTPVEEGAINLNFLGTNGLFVAIIIGLLV
                     VEINRLFEVKNIKLKLPDTVPPMVATFINMLVPLLTNIFIFYGINLIFLAATNKIFPE
                     AVMEVLTPATNIAGSLGGFLLIVTLGNILWLFGINGSSIIFPIVFTLGMAQTGLNAEQ
                     LANGETMTHLMNLQMFRISVLGGAGGTLGLVLLMMRSKVPEYRTIGKLSLVPGICSIN
                     EPVIFGLPIVFNPILAIPFLITPIISLLLTYFAQQLGWIGIGFIVDPSFTPFFAQAYL
                     SSMDWRNILFCLLLIVISIFIYYPFFKVMESNKTKLVDEKL"
BASE COUNT         1585 a          708 c          847 g         1388 t
ORIGIN      
        1 ttataaactc catttgcttt cgcaatttta atgccttgcg cctggcgtcg tttagattcg
       61 gtacgctctt gttcagcgat catggccaaa atttggatga tcagatcctt aatgaattta
      121 tccaggagag ggttgccaat tgcttcagcc atgatcggta gactggtgat gattagctgt
      181 acgtttttct tctttaggta attgactgaa gcgatgatct cgtcgtaatt tcttccaagt
      241 cgatcaatag cttccacaat aaaaatgtct tgatctcgga cgaaatccaa tgcttcttgg
      301 aaaacaggtc gatgagtaat cgttgcgccc gattgtttct cgatgaaaat tctcactgca
      361 ccgaattttt tcatttcttc aatctggcgt tgttcatttt gatcgatgga tgagacacgt
      421 atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaat acaccctaat
      481 catacacgat aaaaccagat ttttcaatgt tgtggtcgtg tctagttagg gtatacctta
      541 tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt taaatggcaa
      601 tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat taaaaatata
      661 ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta agaaaacgtt
      721 ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt atctttaggt
      781 attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc tgatagtaca
      841 aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga taggaacgga
      901 atagccattg gtaacccaac taacgactta actgttactg aaaattattt aatagtttct
      961 ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat gatttttgat
     1021 aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa aagaaatggt
     1081 tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa caattggatt
     1141 gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga atttgtgaac
     1201 acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc gaaagaagaa
     1261 tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa atcaatttct
     1321 aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata tcaaaaagaa
     1381 aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa ttgaaagtgt
     1441 tcataaaatc acccatttct ggacactttc tgtcattttt atatttaatt ggcacagttt
     1501 tttctaatta tttgtcatat tcatagtcaa ctatagctac aaaagcaact aattttggag
     1561 atagattgag atatttaaaa atctatcatg aaaaattagt tgcttttgtc acttagcgct
     1621 gaaaatttat gccatttatc tagaaaaatg acaacagagt tgggcaacag aatttaaaaa
     1681 tgatccggat ttcagaattt taaaggagtt ttattatggc gaaaattggg tatgctcgag
     1741 taagcagctt agattaaaat ttagaccgac aattagaatt attatcagag tgtgataaaa
     1801 tttttagtga taaagcaagt gggaaagata ccaatcgaga aggatttcaa gaaatgatga
     1861 aattcatacg tgaaggtgat attgtcgttg tgacagaatt aaaacgactt gaacgaaata
     1921 acaaagagct aacagaaacg atgaatttaa ttcagctgaa gaaagctaca ctggaagttt
     1981 tgaatttgcc agcgttaaca ggtatcactg atgataattt acgtcgatta cttaataact
     2041 taattatcga actatacaag taccaggccg aagaagaacg tcggtatatt cgcgaaacgc
     2101 aacaacaagg aattgcactc gctaaagcaa aagggaaata caagggaggt acgccaaaat
     2161 atcgtgagaa tgatccgcga cttcaattag catttaattt gtttttgact agatctacag
     2221 ataaagaagt tgaagagcta acagggatta atcgtagaac gtttagaaga tatcgaatga
     2281 aacatggtat tactaatgaa gttagggagc aaaaaaataa atctttcagt tgaggctaat
     2341 ataattttgc aagaaaggga tttttatgaa agaaattaga ttttcaaatc aaaatatgca
     2401 gaattactat aatgaaatta tgaatatgga aactagtgaa ttgaatttaa ttatagccga
     2461 aaaaaaagtt gcattggata ggaataaaaa cttattaaat gtagttatga tctgttatat
     2521 ttcatttcta atactaggtc ttccacaagc agtgtttcct gaaatgtttt ctggagactg
     2581 gggtattgtc agctattcta tattaacatt gattgctatg gttttaggta cttcatttta
     2641 taatgctttt gtaagtaagc atgttgagga atatgaagta ttaatgtact taaaagagaa
     2701 aaaaacaagt aattaatatg agaacaccac gcatagtttt tattttgaga tatcctagaa
     2761 tgaaacacat taagaacgaa agcaaagcaa aagacggcag aacttctact accttctaag
     2821 ttttttcata tttgtttgtt atgctataca tagatctgca taattagact tgcgctgccc
     2881 gttattgaag tttcaggcag cgctcttttt gggggatcga taatggaaga agaaaaaata
     2941 tttgagaaac gctggcagct agcatcaagt gaacaaagag caagatacaa taatttgatc
     3001 acctcctacc ccactgttga ctagacatat aaggaaaaga aatacttact ttggctgtgc
     3061 cagttagata tagatacctt tgaaacattt gaagtgatcc tagataaaat taaacagaat
     3121 tgatcagaaa caagcgaagc cttctctcgg ttcgcttgtt ttgctattta ttagttggct
     3181 cagggcaatt ctaagctcgt ttgaaagaaa accgaatgac gactatagtt tttcatctac
     3241 taattttgtt ttattgctct ccatgacttt aaaaaatgga tagtagatga agatgctgat
     3301 gacgatcaac agtaggcaaa agagaatatt gcgccagtcc atacttgaaa gataagcttg
     3361 tgcaaaaaaa ggtgtgaagg aaggatcgac gataaatcca atcccaatcc atcctagttg
     3421 ctgagcaaag taggtcagca ataatgaaat gatgggcgta atcaaaaatg gaattgccaa
     3481 aatagggtta aaaacgatag gtaatccgaa aatcactggt tcgttgatgg aacagattcc
     3541 aggaaccaat gacaattttc caattgtgcg atattcgggt actttgcttc gcatcatcaa
     3601 taaaaccaaa cccaaagtac caccggctcc accaagtaca gaaatacgga acatttgtaa
     3661 gttcattaag tgtgtcatgg tttcaccatt tgccagttgt tcagcattca aaccagtttg
     3721 agccattccc aatgtaaaga cgatagggaa aataattgac gagccattga taccaaatag
     3781 ccataggatg ttacccaaag tcacgatcaa taagaaacca cctagactgc cagcgatgtt
     3841 cgttgctgga gtcaggactt ccatcaccgc ttcagggaag attttgtttg ttgctgccaa
     3901 gaaaatcaga ttgatgccat aaaagatgaa tatatttgtc agcagtggaa cgagcatatt
     3961 gataaaggtt gctaccatgg gtggaactgt atctgggagt ttcaacttaa tattttttac
     4021 ttcaaatagt cggttgattt ccactactag caagccgatg ataattgcga cgaacaatcc
     4081 gtttgtccca aggaaattaa gattgatggc accttcttcc actggtgtac aaaccattag
     4141 ataaatgaca gatgcaacca tgccattcat ggaaggatta attttgtatt cattggcaag
     4201 ggaaaatgca atgccaaaaa cactaatgaa tccgatgatt cccattgtca aattataagg
     4261 ggctgtgatg agatcataat ttgctacggc aaaatctttc cagctggcca taaatttcat
     4321 gaaaatatta gctgtatctg gattgtattt atcaatattg atgggtggat ttgcaaaaat
     4381 cagaaaaaaa gaaccgataa caataaaggg taggccaaac atcataccgc tggatatagc
     4441 ttttaggtgg cgctgattac ctatcttggc tgcgatgggg ctaagtatgt cattcagttt
     4501 catgataaac gcagaatttt ccatataa
//
LOCUS       DAIGTA010000112         4461 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.120, whole genome shotgun sequence.
ACCESSION   DAIGTA010000112 DAIGTA010000000
VERSION     DAIGTA010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.120"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            574..1008
                     /locus_tag="NOB43_002664"
     CDS             574..1008
                     /locus_tag="NOB43_002664"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983481.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="NOB43_002665"
     CDS             2298..3221
                     /locus_tag="NOB43_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI0983482.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="NOB43_002666"
     CDS             3237..3776
                     /locus_tag="NOB43_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI0983483.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DAIGTA010000113         4430 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.121, whole genome shotgun sequence.
ACCESSION   DAIGTA010000113 DAIGTA010000000
VERSION     DAIGTA010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.121"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(543..2048)
                     /locus_tag="NOB43_002667"
     CDS             complement(543..2048)
                     /locus_tag="NOB43_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0983484.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="NOB43_002668"
     CDS             complement(2045..2731)
                     /locus_tag="NOB43_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0983485.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQFKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOB43_002669"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOB43_002669"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCI0983486.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          918 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgaattggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DAIGTA010000114         4403 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.122, whole genome shotgun sequence.
ACCESSION   DAIGTA010000114 DAIGTA010000000
VERSION     DAIGTA010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.122"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(153..383)
                     /locus_tag="NOB43_002670"
     CDS             complement(153..383)
                     /locus_tag="NOB43_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HCI0983487.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEREPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(613..1431)
                     /locus_tag="NOB43_002671"
     CDS             complement(613..1431)
                     /locus_tag="NOB43_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0983488.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1592..2281
                     /locus_tag="NOB43_002672"
     CDS             1592..2281
                     /locus_tag="NOB43_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCI0983489.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2295..3797
                     /locus_tag="NOB43_002673"
     CDS             2295..3797
                     /locus_tag="NOB43_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0983490.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            3810..4286
                     /locus_tag="NOB43_002674"
     CDS             3810..4286
                     /locus_tag="NOB43_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0983491.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKYGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT         1459 a          633 c          781 g         1530 t
ORIGIN      
        1 tctgaagctg tattaaatac agatagatta atataaaaat caaaaggatc ataaactttt
       61 aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttatctca taacattgaa
      121 gtgttttgca attttagcat tgaaacactt ttttaatctt caacgttgtt cttataaaca
      181 agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt tatagaaaac
      241 attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc agtaggttcc
      301 cgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt atttaagaga
      361 ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta cacgtttttc
      421 tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc aagaaccgta
      481 ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa taagctatca
      541 agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta ggtttagcta
      601 agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt tttctcttaa
      661 ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat cacaaatata
      721 aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa tggctgtttg
      781 taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta tagcaataat
      841 ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg ttttcccaga
      901 taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt gggcttgaaa
      961 atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat tttctaaatc
     1021 aagactagta tttccactag atcccactcc aaatatatat atgttttttg attgagtgat
     1081 cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg aatagagagc
     1141 ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat gttctttttt
     1201 ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag aaaaaccaat
     1261 tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct taatatcact
     1321 catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga cttttttttc
     1381 agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca tacaaactcc
     1441 tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact cctaaatact
     1501 ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag ttgttatcca
     1561 aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt tagatcttat
     1621 ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt acaaagagga
     1681 agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag ttggtatacg
     1741 tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac caatgattgg
     1801 aattattaaa agagattatc caccagaatc tccattcatt actgccacta tgagagaagt
     1861 agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc ttagaaatcg
     1921 acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat atcctcatca
     1981 gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata aagcaggaat
     2041 agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac aagatgggcc
     2101 agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg ctgagggaag
     2161 gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag gtattgttgt
     2221 gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag cattaagtta
     2281 gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc atgttaccaa
     2341 ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta acaaatgaga
     2401 gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt ttaagtatta
     2461 tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca attggtattg
     2521 ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga gtagcttatt
     2581 tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa gatgcaacac
     2641 tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt ttacacaatc
     2701 gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca agatttattc
     2761 cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta atttggccac
     2821 caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt agtttaggaa
     2881 cttttttata tggtttttta ttacgtttaa caggtgctgt tggactacac cacaccattt
     2941 accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga tcaacaattg
     3001 ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact ggtctgttta
     3061 cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttggg ttaccagcag
     3121 catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat ggtgggcttt
     3181 attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt gaatatatgt
     3241 ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga ttatcttttt
     3301 attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt ttgatcgact
     3361 ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa ttaattcctt
     3421 ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc aaaaaattta
     3481 aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa gtaataaaca
     3541 aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt ggaaaagaaa
     3601 atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttaca aatggggaga
     3661 ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa gtgaagggtg
     3721 gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc aatcaaatat
     3781 taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag aaaaaacaag
     3841 aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta aatgatcctg
     3901 tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt tcaaaaattt
     3961 atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct attaatataa
     4021 aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt gaattacaag
     4081 gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa acctcgttgg
     4141 ttgatgtgga ttttgacaaa ataataaaat atggtaaaga tacttctgtt atagttgttt
     4201 ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt gctcatggga
     4261 attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa aataagctaa
     4321 ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt ctgttcattt
     4381 ttttatttta ttagtaatga ttc
//
LOCUS       DAIGTA010000115         4386 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.123, whole genome shotgun sequence.
ACCESSION   DAIGTA010000115 DAIGTA010000000
VERSION     DAIGTA010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.123"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            2..74
                     /locus_tag="NOB43_002675"
     tRNA            2..74
                     /locus_tag="NOB43_002675"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="NOB43_002676"
     tRNA            78..150
                     /locus_tag="NOB43_002676"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="NOB43_002677"
     tRNA            155..225
                     /locus_tag="NOB43_002677"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="NOB43_002678"
     tRNA            238..311
                     /locus_tag="NOB43_002678"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="NOB43_002679"
     tRNA            323..394
                     /locus_tag="NOB43_002679"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="NOB43_002680"
     CDS             660..1853
                     /locus_tag="NOB43_002680"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCI0983492.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="NOB43_002681"
     CDS             1983..3455
                     /locus_tag="NOB43_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0983493.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="NOB43_002682"
     CDS             3538..4326
                     /locus_tag="NOB43_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCI0983494.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
BASE COUNT         1282 a          732 c         1021 g         1351 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 atagga
//
LOCUS       DAIGTA010000116         4375 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.124, whole genome shotgun sequence.
ACCESSION   DAIGTA010000116 DAIGTA010000000
VERSION     DAIGTA010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.124"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(83..1051)
                     /locus_tag="NOB43_002683"
     CDS             complement(83..1051)
                     /locus_tag="NOB43_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0983495.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1500..2906)
                     /locus_tag="NOB43_002684"
     CDS             complement(1500..2906)
                     /locus_tag="NOB43_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCI0983496.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQTNIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPNLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDVHEYKEIMSEISELRQTAVKERESVSDELRYISRQREE
                     NEREKALVASERVKIEEEKKNMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQRKLERSEDEIEW"
     gene            complement(3127..3489)
                     /locus_tag="NOB43_002685"
     CDS             complement(3127..3489)
                     /locus_tag="NOB43_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983497.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENATMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDGLFGVITNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3493..3831)
                     /locus_tag="NOB43_002686"
     CDS             complement(3493..3831)
                     /locus_tag="NOB43_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983498.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERIMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(3810..4229)
                     /locus_tag="NOB43_002687"
     CDS             complement(3810..4229)
                     /locus_tag="NOB43_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983499.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(4222..4362)
                     /locus_tag="NOB43_002688"
     CDS             complement(4222..4362)
                     /locus_tag="NOB43_002688"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983500.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYVYGVAESNGED
                     ND"
BASE COUNT         1251 a          978 c          603 g         1543 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga gggggctgtt aatttttccc
     1021 actcatttat gatcgtgcct tttttactca aattttgttc ctcctcaaag aaaaagagac
     1081 ttctggaaag aattttcaaa agttcacgta actcttaaaa attcattacc aaaaaatctc
     1141 tagtcttgaa gaaatctaaa aatattcgta taatgattaa gaagttacgg agctagtgcg
     1201 attagtttcc gtaaaggtcg agaacgtgtc cagcgttgct cgactttatt tttttgctct
     1261 tttttcagtt tatttatttg ataactcaat aatagcactt ctctttagct atgcaaatat
     1321 ccaaaaaata aaaccgcacc ctttgaaaag ggcgccccca aacttcgcta acgctaggtt
     1381 ggccaaaaaa tggacttgcc attttttagc aaatgtcagc ttcagggatt agtggtttag
     1441 ccgtcaactc cttatcctcg gcacaaaccg cctccggtac cgttgactgc acatcgtaac
     1501 taccactcga tctcatcttc agaacgctct aatttacgct gtgagacgtt ttgacgataa
     1561 aataaggttt tctcctgctc taacacttct aattcctcag aaagccccat atccttttct
     1621 gcaagaccaa aacggataga caaacgagtg atcgattttt gaaatgcgtt ttttaatcgc
     1681 tctaaacgct ggcgtaaaga gcgattttct tctttcagct ttttattttc cacttgtaaa
     1741 tctgctaatt gttttctacc agacaaatga cgctcttctt ccaatgtagc tacatactca
     1801 tttaattctg tattttgctc aagcatctgt aaatattgct cactcatgtt atcagcattt
     1861 ctcttggcat ttgttgctct cgtagctcgt tgatacaaat caacaaaatc attcccagat
     1921 aaatgatacg aaccatcagg aagcctcttg aaactttcta aaggaacaat atctttttgg
     1981 aaaatgaccg ccatctcttt ttttacattc agcatatttt tcttctcttc ttcaatcttc
     2041 actctctcag aagccaccag agccttttct cgctcatttt cttctctttg cctagaaata
     2101 tacctcaact catcagaaac gctctcacgc tcttttacgg ccgtttgacg caattctgaa
     2161 atctcgctca tgatttcttt atattcgtga acatctttga ttttgttagt accgactaac
     2221 tcacgctccc aaccaaaatc tgccatcaaa cgttcaattg actcaacttc ctgattccta
     2281 aaattattcc aaatcactcg accattctct ttatctgctc gtaaaccctg ctgttgcaag
     2341 gctttgttaa aacttggttg cttttgaaca ccccgtttat acccttcagc aacaggaaca
     2401 atattcaaat gcaggtgcgg acttacttcg tcattatgaa taacagcatt gtagacggat
     2461 aaattaggat tccgttcttt aaattctttg aaatattcaa ctaaaatttt gttggcaatc
     2521 actcgatttt gttctgcttg ttgttccgat atgccagtag aagaaccatc atcacgagta
     2581 gtacgaaaat catcaagagt accaatttgc acgataaatt ctcgctgtgg ttccaatttt
     2641 ttatccttgc gaacctttgc taaatagtcc tcgatttttc tatcggctct tttctgcttt
     2701 gcattatatt tttctacggc ttcaccgaat aattcttcat atttttcacg aatatttgtt
     2761 tgttctaaat agatattttc atccgatttt gtgaaatcaa tatgcttatg ccagtcattg
     2821 attttttggc tatcagttaa ctcacgatta ttatgagaaa tgcttgtatt ctttgttccc
     2881 tttttgaacg aaatactgaa ccccaagtta aaaccctcct tcggctgtcg ctaataaaaa
     2941 gagtgtaaac ctttctgtta ctctttgtca aagagtaaca ttttcctaat tgtgacatgg
     3001 ctgtcacaat tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag
     3061 gagccgaaag cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat
     3121 aatcgcttat cgtaaattca cgtcattaaa tattgacgta aatttactct cactcatctg
     3181 acttttctta ttcgttatca ctccgaataa gccgtcagat tcatcgggat aatctcgttc
     3241 gcttggcgct gatttttcat cagcaagcca ctcattatcc actgtttttt cgtgttgctg
     3301 atcgtcagaa attgacgata accaccgctc aaaatcagca aaagattcaa acccaaaacg
     3361 cttgcgaaga gccttgccca ttgtagcatt ttctttctca atcaagcgtt ttttctgttg
     3421 acgaagtttc gcttgttctt tttttaattt ttcttcttgc gctttaatat ctgctaaagt
     3481 cattcccata aactacatct ccttttcttt ggaattaata acggaaattt ggtttaactg
     3541 cataacatga ctcattaatt tcaaccaaaa ttctttttct gattcatcag ttgtttgcgc
     3601 taaatgctta tgaacaaatt cattagtcaa aactgaagat tttgctaaat cagcattgat
     3661 aaccgagttg agaacatcca taattcgttc aagcatttca ctataattat cttcatccgg
     3721 caaattcaaa taatcagcta accgttcata catcaattca attctatcga ctgtttcttc
     3781 tctcaaatca attttatcca tgtcacacct cacttccaga attgccacca ttttcgattt
     3841 tttaattctt gattttctag taacaactga tcgttttttt gttgctgaag caaagtcaat
     3901 ttttgttggt cacgaatcat ttccgttaat tcagaaatat gcctatcttt ttccgctaat
     3961 tgttcacgca aaaattcatt ttctttttct aacgggaaat cattgcctgc atcattgacc
     4021 ggtaaatcac cagtcaattg accacctttt gaccgataaa ttgaccgcac aacaccaatc
     4081 aattccttgt ctaacatgat aaccccatta tctttatacc gagcaaggtc ataacctgca
     4141 ttgaccagtt gattgcgcac tgtattttta gatataccca actcatcagc aaggtttttt
     4201 atggtcattt tttctggcaa atcagtcatt atcttctccg ttactttcag ctaccccata
     4261 aacatattta acagcatgct tagggataat gattggggaa tcaattttat tatttttcaa
     4321 aatcaactca tactgcgtta catcaagtaa cttaccggac atttttttgc tatcc
//
LOCUS       DAIGTA010000117         4335 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.125, whole genome shotgun sequence.
ACCESSION   DAIGTA010000117 DAIGTA010000000
VERSION     DAIGTA010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.125"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..665)
                     /locus_tag="NOB43_002689"
     CDS             complement(<1..665)
                     /locus_tag="NOB43_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HCI0983501.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENE"
     gene            780..2492
                     /locus_tag="NOB43_002690"
     CDS             780..2492
                     /locus_tag="NOB43_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983502.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            2495..4267
                     /locus_tag="NOB43_002691"
     CDS             2495..4267
                     /locus_tag="NOB43_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983503.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         1339 a          753 c          922 g         1321 t
ORIGIN      
        1 tgctcgtttt ctcttctttt attttgttgg cataagcctt caatataggt ttgtgcactc
       61 gttagaaaga gtgctttttc attcaattct gcatgggact gcatactttc tttaaatccc
      121 tctaattgat tttcaactac ataattacgc ataaatagaa ctgtttcttt caaaaattca
      181 tttccgtcca taattttttg tcgaagctgc tgttcatgct gctgatccat taactgtcca
      241 atcaataaat tgtggagaga ggcaatggcc tgatgacttt gggtgactga aaatccttca
      301 cgaacaagta attggatcat ttgctccaaa tgttctaatc gactcggaaa agcgggcaca
      361 gtattgattt ctaattctgc cccacaaggg aaacgtgtat aaaggtcata gtaattttcc
      421 atatactgca gcaactgttc attccaaggc aaagttggat ctggaagcgc taattcttct
      481 tccattgttt cagccatttt ttgcaagagc tgttgtttgt ttttgaaata ccaatataaa
      541 gcaggtgctt gaacatgaat tctgtttgcg atgtttcgca tggaaagctg cgaaagagct
      601 tgtgtttcag ccaggatatc aaaggcggcc tgaatgatga ttgcttgaga aagctttatt
      661 tccattttat caacctcgtg tattgcatta tctttttaaa catggtaaat tgttagtcgg
      721 tctaatttta cagtgttaaa ttagtcctgt caatttaaac aaaggggtgt aatcaacgaa
      781 tgaaattaat cttacgacat gcgaaaaaat ataaagtagc tgtttttatt tccttgctgt
      841 ccgtagcagt catggttgca gcagcattat ggcaacctaa gttactacag caagtattgg
      901 aagctattat tacagaagat aatgatgaaa tgaaaacaat tggtatttac ctgatcagtc
      961 tggctttgct aggattagcc gcaggtgtaa cgaacacgat tttctctgca aaagtagctc
     1021 aaggcgtaag tgcagatatc cgagaagaag catttcgaaa gatccagaca ttttcatttg
     1081 gaaatatcga acagttctct gctggaaatc ttgttgttcg tctaacaaat gatatcacgc
     1141 aaatccaaaa tttagtgatg atttctttgc aatcactttt tcgaattcca ttcttattta
     1201 ttggtgcctt cattttagct atgatcacga tgccgcaatt atggtggatc atcgtagcgc
     1261 ttatcgttac ggtatttctg attacggcac tttcatttac aaggatgggc aagcacttca
     1321 tgatcattca aaaactgatt gatcgtgtga atagcattgc aaaagaaaac ttactaggga
     1381 ttcgtgtagt gaaatctttt gtacaagaag aaaaccaatt gaagtcattc agcaaagtaa
     1441 gtgaggactt aacaaaacac aacatcatag tcggtacatt attttctgtg atgatcccgt
     1501 ccttcatgct ggctgccaat ttggctgtgg ttggggcgat cttttttgtg agcgatcttg
     1561 ttaaagatga tcctacgtta attggtggaa ttgcttcatt catgaactac ttgatgcaga
     1621 ttatgatggc aatcattatt ggcggaatga tgatgatgat gacttcaaga gcagccgtat
     1681 cgctgaagcg gattgcggaa attttagatg ctgaaccaga tcttacttat ttagacgttc
     1741 cagaacaaga gttgacgggt tctgtcactt ttgaccatgt ttcttttcgt tatcctggtg
     1801 aggatacaga tacgcttaaa gatatcagct tttctatcaa acctggagaa atggttggta
     1861 tcgtcggggc gactggtgcc gggaagtcaa cactagcaca attgatccct cgtctatttg
     1921 atccgacaga aggcaaagtt gaagtaggtg gtgtagatct tcgtcaagta aatgaaaaga
     1981 gtttaagaca aacggtttcc tttgttttgc aaaaagcaat tttattctca ggaacgattg
     2041 ctcaaaactt gcgccaaggg aaaaagaatg caacagaaaa agagatggaa catgcttctt
     2101 ctattgctca agcaaaagaa ttcatcgaaa agttatctga tcgttacgaa gcaccaatag
     2161 aagaacgtag cagtaacttt tctggtggtc aaaagcaacg tttatccatt actcgtggcg
     2221 ttatcggtaa tccaaagatc ttgatcctag atgacagtac gagtgcactg gatgctcgct
     2281 ctgaaaagct ggtccgagaa gcactcgatc gagatttgaa gggaacaacg acgattgtca
     2341 tcgcacaaaa aattgcttct gttgtcaaag cagaccgcat cttagtattg gatgaaggca
     2401 gattagtcgg cgaaggaacc catgaggaat tggtagctgg aaaccgtgtc tatcaggaaa
     2461 tctttgaaac tcaaaaagga acggaggagt aagtatgact gatctaataa aagcaagtaa
     2521 atttttctat cactatttga agcggtacaa actctccttt ttctttatct ttatcacagt
     2581 gatcattgct acctatctac aagtaaaggc acctcaatac atcggggaag cttttcaaga
     2641 attagctaat tacgtaggag gcttgatgca aggcgtagac gataaaagca aatttgtttc
     2701 tgtaatatgg aaactcttgc tgttttatgt actagctagt gcagccaact ttatctatag
     2761 tattttgttc acacaagtag tagggaagtc aacgaaccga atgcgtatcg gtctattcaa
     2821 caaattggaa aaattgacga tccgtttctt tgattctcat caagacggtg aaattttaag
     2881 tcgttttacc agtgacttag ataatattca aaatagtttg aaccaagctt tgcttcaagt
     2941 catcacgaat gctgttttac ttgtcgggat cttgatcatg atgttccgcc aaaatgtaga
     3001 gttagcttgg gctacaattg cttccactcc agtagccgtt ttgatagctg tcttgattat
     3061 ccgcaaagca cggaaatatg tggatcttca gcaagatgaa gtggggaaac taaatggtta
     3121 tatggatgaa aaaatcagcg gacaacgtgt catcatcaca aatggcttac aagaagaaac
     3181 gattgaagga ttcttagagc ataatcaaag tgttcgcgaa gcaaccttca aaggacaagc
     3241 ttattctggt ctactatttc cgatgatgca aggaatgtca ctggtcaata cagcgatagt
     3301 tatctttttc ggcggctggt tagcattaaa tggtgatttg gaacgttcgg tggcattagg
     3361 cttagttgtg acattcgtcc agtattcaca acaatattac caaccactga tgcagatttc
     3421 atctggatac agcatgatcc aattagcgat tacaggggca agacgattga atgaaatatt
     3481 tgatgaaaaa gatgaagtca aaccagaaaa cggtaaagca tttgatggtg ttgaaaaagg
     3541 tcttgcgttg cagcacgtag attttggtta ttctccagaa aaactagtct tgaaagatgt
     3601 ctcgatcaat gtggacaaag gagaaatggt tgctcttgtt ggtccaacag gatcggggaa
     3661 aacgacgatc atgaatctgc taaaccgttt ttacgatgtc aatgatggtt cagtagtcat
     3721 cgatggaata gatatccgag attatgatct tgatgcatta cgtagacatg taggaatcgt
     3781 tttgcaagaa tctgtattgt tctccggaac gatcaaagac aatatcacat tcggcaaacc
     3841 ggacgcttca gatgaagaag tcatcaatgc agcaaaacaa gcgaatattc atgacttcat
     3901 catgacgtta gaaaaaggtt atgatacaga gatatccgaa gaaaataact tattcagtac
     3961 aggtcaaaag cagttgatca gtattgctcg aacgatcatc acaaatccat ctttattgat
     4021 tttggatgaa gcaacaagta atgtagacac ggtaacagaa gcaaggatcc aaaaagcaat
     4081 ggatgaagca atcaaaggaa gaaccagctt tgtgattgct caccggctga aaacaatctt
     4141 gaatgcagat agaatcgttg tcttgcgtga tggggaagtc attgaagaag gcagtcatca
     4201 tgagttatta gcagaaaatg gattttatgc ggaactttat cataatcaat ttgtatttga
     4261 aagttaaatt aaaagaacct cgttataacg gggttctttt tatatatttt atgttgtttg
     4321 tttttataag gggca
//
LOCUS       DAIGTA010000118         4298 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.126, whole genome shotgun sequence.
ACCESSION   DAIGTA010000118 DAIGTA010000000
VERSION     DAIGTA010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.126"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..429)
                     /locus_tag="NOB43_002692"
     CDS             complement(<1..429)
                     /locus_tag="NOB43_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI0983504.1"
                     /translation="MTYVFLPKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISV
                     FGDVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILAVATVGLYGIGDCI
                     FTGLFSINTNESSWNLSTWIHNTGSGLGYAGFLLFPLLLVL"
     gene            complement(487..1539)
                     /locus_tag="NOB43_002693"
     CDS             complement(487..1539)
                     /locus_tag="NOB43_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0983505.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(1552..2490)
                     /locus_tag="NOB43_002694"
     CDS             complement(1552..2490)
                     /locus_tag="NOB43_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI0983506.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(2940..3590)
                     /locus_tag="NOB43_002695"
     CDS             complement(2940..3590)
                     /locus_tag="NOB43_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983507.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(3690..4199)
                     /locus_tag="NOB43_002696"
     CDS             complement(3690..4199)
                     /locus_tag="NOB43_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HCI0983508.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
BASE COUNT         1388 a          907 c          618 g         1385 t
ORIGIN      
        1 cagaacaagt aacaatggga aaagtagaaa gcctgcatag cctagcccag aacctgtatt
       61 atggatccaa gtcgatagat tccaagagct ttcattcgta ttgatactga ataacccagt
      121 aaaaatacaa tcacctatcc catataaacc aactgttgca acagcaagta ttgcaagtgt
      181 ttttgatgtt ccaacaaata ggtgatacaa cgcaggcaac gaaagaacaa aaaaaagtcc
      241 agatacaact gaccagacca agaaagcacg tctgactgga ctatctacgt caccaaacac
      301 actaattacg gtagtcattt gattcagttt gggataaaaa aggccaagga tatacggtgt
      361 cgataaatca ctaatcacac ctaataataa aaaataaaaa ccatattttg gcaaaaaaac
      421 gtaagtcaga tgttgttgac atctcactta cgcatccatt gattgaaaat ttcttagtaa
      481 aatctactag cctaaaaatt tgaagacttc ttctcgatca tacagtttaa atactttctc
      541 gcataaaaat tgagtaatta gtgccgcaaa aacagggatg actaaccaac aaagaacaac
      601 aagaaagcca tttagccctg catctaaaga agccaacgga ccaacaagtc cgaccacacc
      661 gaaaccagca gaagcaggcg tacctgaaat agaaaataga gcgacaggaa tagctgtaat
      721 cactgcacta actaaacaag gaataagaat cacaggtttt ctaaatagat taggcatcat
      781 catcttcata gcgcctaaag caatcgcaat tgtcacacct gacttattaa ccttccaaga
      841 gttcactact aaaacaaaag tggttgcagc tacgcccatc gcagccgcac cagcagaaac
      901 accatctagt tggattgcca ttccgattgc tactgttgaa ataggagaga taatcaaaaa
      961 ggcaaaggaa caaccaatca agatagacat taacagcggt tgtaaggtag tgaagttatt
     1021 aatcaatgat ccaattgcag aagtaattgc tgttacaaaa gggaataaat aaaaaccaag
     1081 taaacctgca cctacaccta caacaatcgg tgttaacaca atcgacactg acccaaaact
     1141 atttccaatc agtaaaatca gcccgacagc aatcgatgct gtcagcatcg tattaataat
     1201 atcgcctgta ccagcaccaa cgtaaacacc cgtttcaccc aaatcaggtg tgaatttgac
     1261 tacaccagaa ccaacaaaag aagctccggc tacaaccatc attctcatcg gatcaaatcc
     1321 aaattgtaag gcaatcaaac caccaatgat caaaggtgtt gctaattgaa aaataactgc
     1381 taactgtgcg atcgttaccg caaagggata cgcactaaaa tattttaaaa tagcacctaa
     1441 tactgcatta ggaatcaatc caataatgat tcctgttgct gtaccagcga ggactttatt
     1501 cagaaaaatt ttcggtgata ttttttgtga agtttccatt caatctctcc tttattttac
     1561 gttcaaacta tcttcttttg catggacaag ctcagtcaag aaatcacaat aaggcgtcgc
     1621 aacaccatat ttcttccctt ttctagaaat tgcgccattg atataatcga tttctgttaa
     1681 tcgatggttc ttaatcaagt cttgatacat tgaaggataa tgtaacccaa ttgtttccgg
     1741 gtcaaaacaa gattcacaat gtgcaatgac ttctgggaca tctagttcaa tcttctctac
     1801 tgctgctact ttggcaaact cattgacaat cgtcgccacc attttatgag cagtcgatgt
     1861 ttttcctagc tcagccatat taacgtctaa gattgtgcat agtccgttca ttgttccgtt
     1921 cacacatgct ttgcgataaa tagaatagtg aatattgtca gaaaaatgag catttaatcc
     1981 tgattcagac aatttgtctg ctaatttttt tgcagctgct tcttttccat cacctaaatt
     2041 ttgtaattct actgaaccac ttccaaataa tttgacctga ccaggacctt caagacctgc
     2101 cgtccacatg gtatttccaa tatagatatt ttccattggt acaaatttct caataatatc
     2161 ttcatgcccg ataccattta atagacataa gacctctgta tcttttttga ttaatgattg
     2221 gatatcctgc agcatttttt ccagctgcat cgctttggta aatagaataa tcagatcaac
     2281 ttgatcttct ttttctactt cggattgaag aacgattggt agttttgctt ctacctcttt
     2341 accattaaaa tttgcttgta atccatgttc tttgatttgt tggacatgtt ctgcccagcc
     2401 atcgattaat aatacttcgt tcccactttg gtgaagcatt aacccaaagc gacttcccat
     2461 tgcgccagcg cctgcaattg ctattttcat tgattcttcc tcctttttct ttctattata
     2521 cttatttgag aatcatttca caaccttgtt ttgttattct tctcttattt atcatgttta
     2581 tatccaccat tcaagttatt ttatcagcaa atcaataaaa ctggaataga atcccaattt
     2641 catcgtaaga gaaactagac tagcaataag aaaatagaaa cattcataga aaaaacctca
     2701 ctcctctgat tataaaagag ggggcattaa cctcgtgtat actaaaacct tccattcatt
     2761 cgatggatga ttttcttttt gtgaaaaaat attcattgta gtacgatgtt gcgcaacaca
     2821 gacggatggt attgcttatt atttattaaa atcgaacaat acacttattc aaaaacttct
     2881 ttcccagatt ttcttccatt tttacagtta taactagtat tatcatgaaa aatagccttt
     2941 tattgtctat gggaataata atttaaaatt ggtacttttt tattaattag ttcatcgccc
     3001 aataatctct ccagtttctt agcatctcct gactcaaccg gaattatcca agcccagtcc
     3061 aaataatttt ttaaaatctc atcatatttt gcaaatattt cattgccata ttccgtcctt
     3121 aaaattatat tttcagtgcc agacaagtga tttgtattga gttgataaaa aagatctcca
     3181 tctaaaaaaa tatcattaga agaagatttc cccacagtaa tgaccattcc atcagctcta
     3241 tgtgttacat acaaataatt gtatgacctc atttcaccta atgaatcaat tatttcttgc
     3301 cctttagctc taatatattg atctctatta cctatctcac tcttatttaa caaaagtttt
     3361 ttcatgtcaa atttaatcgg ctgttttatt tttgtaaatt cgcttctact actaatccaa
     3421 tccgagatta atttttcaac atgtcccaga gtaaactctg atttattcgc taaatacttt
     3481 ttttgttgta ttaaagacat ctttccccga agctcaaaat tgagcctaca tcgattctct
     3541 atctcttcaa aaagcatctt atcttcatca ttcttatatt catcattcat aaaaccaatc
     3601 cagctcctcg attaagataa tattttaatc tcatacaaaa actagctctc atcaaaacaa
     3661 ccattgtttt gatttctcat gaaatttctt tatacttttc tccgattata aattcctaac
     3721 cccttgagaa aattacgcat atatttatct ccgcaaggct taaaatttcg ttggccttct
     3781 tttctcaaaa atgccccgat ttcgcctttt gatggataga tttctgcctc agcaaaaacg
     3841 tctaaaatat catcagtggt catagacaag gcgattttta atttttttag caacacattg
     3901 ttgatatatt tgatttcctt gcttttttgc ggcgtgtcta ctatcggctt atctttttgc
     3961 ggaccacgtg ccaagagaat caggccattt aggaatgcgt caaaaacttg gttgttgatg
     4021 gttttttcat acacattatt ttctgcatta tctttgttct tatcctgtac tttggtcagt
     4081 accgcctgag cttcttcttt agtcagtggt acaccgccta gctcaaaagc tttaatcaaa
     4141 tccgtatctt tcaaatcaat cgcataacgc aatcgcaata acctatcatt gttattcatt
     4201 tgttcctccg aagtatttag tctttacttt cttacgtact ttttgtcttg ctaagatttt
     4261 taggatcaat gataaaaacc gcatcactta tgataagg
//
LOCUS       DAIGTA010000119         4157 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.127, whole genome shotgun sequence.
ACCESSION   DAIGTA010000119 DAIGTA010000000
VERSION     DAIGTA010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.127"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            179..775
                     /locus_tag="NOB43_002697"
     CDS             179..775
                     /locus_tag="NOB43_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0983509.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="NOB43_002698"
     CDS             899..2698
                     /locus_tag="NOB43_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI0983510.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESMKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="NOB43_002699"
     CDS             complement(2976..3188)
                     /locus_tag="NOB43_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983511.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="NOB43_002700"
     CDS             3650..3799
                     /locus_tag="NOB43_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983512.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="NOB43_002701"
     CDS             complement(4052..>4157)
                     /locus_tag="NOB43_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0983513.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1229 a          707 c          728 g         1493 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagta tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAIGTA010000120         4034 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.128, whole genome shotgun sequence.
ACCESSION   DAIGTA010000120 DAIGTA010000000
VERSION     DAIGTA010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.128"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            73..234
                     /locus_tag="NOB43_002702"
     CDS             73..234
                     /locus_tag="NOB43_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCI0983514.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..1530
                     /locus_tag="NOB43_002703"
     CDS             253..1530
                     /locus_tag="NOB43_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983515.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="NOB43_002704"
     CDS             1540..2196
                     /locus_tag="NOB43_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983516.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="NOB43_002705"
     CDS             2196..3572
                     /locus_tag="NOB43_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983517.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..>4034
                     /locus_tag="NOB43_002706"
     CDS             3702..>4034
                     /locus_tag="NOB43_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0983518.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1612 a          440 c          704 g         1278 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catc
//
LOCUS       DAIGTA010000121         3970 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.129, whole genome shotgun sequence.
ACCESSION   DAIGTA010000121 DAIGTA010000000
VERSION     DAIGTA010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.129"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..356
                     /locus_tag="NOB43_002707"
     CDS             <1..356
                     /locus_tag="NOB43_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0983519.1"
                     /translation="EIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKS
                     LEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGN
                     VFKIEYTKKRQRLAY"
     gene            591..827
                     /locus_tag="NOB43_002708"
     CDS             591..827
                     /locus_tag="NOB43_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983520.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            834..2786
                     /locus_tag="NOB43_002709"
     CDS             834..2786
                     /locus_tag="NOB43_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI0983521.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2858..3355)
                     /gene="dfrG"
                     /locus_tag="NOB43_002710"
     CDS             complement(2858..3355)
                     /gene="dfrG"
                     /locus_tag="NOB43_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI0983522.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3585..>3970
                     /locus_tag="NOB43_002711"
     CDS             3585..>3970
                     /locus_tag="NOB43_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0983523.1"
                     /translation="MKYILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTE
                     MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVE
                     PSKPEQREMLLDALLEISDSDPLLRY"
BASE COUNT         1415 a          640 c          697 g         1218 t
ORIGIN      
        1 ccgaaattgt aatcaaacag aaggtagaac tgtatcctaa tatgtgtgtg acgaacttta
       61 ccgaatctga acaatgggat acggtaatag agggaaacga tgacctttta gagaaatata
      121 tgtccggtaa atcattagaa gcattggaac tcgaacaaga ggaaagcata agatttcaga
      181 attgttctct gttccctctt tatcatggaa gtgcaaaaag taatataggg attgataacc
      241 ttatagaagt tattactaat aaattttatt catcaacaca tcgaggtccg tctgaacttt
      301 gcggaaatgt tttcaaaatt gaatatacaa aaaaaagaca acgtcttgca tattaagtag
      361 ttcagttttg gagtacaaaa agtgaaaatg taaacctaaa tgagtatcaa attgcaactg
      421 aatttgatac tcgtttttta ttgttaaatc aacgtttgtt gttaatttac accacaaaat
      481 gtaagttaaa atgtatataa aaatgcgaac gtgaaataat tattgtagga atgcaaattg
      541 gtgtgttaaa atggttacaa tttactaagc aaaaaggggt gcattttcct atgcaatttc
      601 ttgagccaaa aaataagaac gctaagtctg tggattggga aatatcagag caagtaaggg
      661 tgatagttaa gcaatacgct gaatatgcag agcgtactga aagcgaagca gtggatgaat
      721 tcttattgaa cattttagac gataagaagt ttattgaatg gattgccaac aagcgaagta
      781 ataagcggat tgttgaaaaa atgggtatca aagatagagt gggttgatag acaatgacca
      841 agcttaaaag attagccacg aaggaagatg aaattgtaga tgttaaaatt ccgatttcaa
      901 acgaagaatt aaaagatagg gctaaacaat atgatttatt aactccaaaa cgatttgcaa
      961 caaggtataa caaaatgttg ttcttgccaa cgtcttttaa atggaacggt tctgaatatc
     1021 ccattcaata taattactgc atcaatccgt tttgttgtaa ttttgggaaa gaacagcaca
     1081 aattcaaaga tgtaaaaggg aaaccaagtc gatataaaat gactggtagt tccaaagata
     1141 aaggtcataa aggtatgtac tgcaatgaca atcctattgg cagaggtgta tcgcaaaact
     1201 gtacagtaac ccctttatct aattggtctg ttgttgaaga aattaaacgc cttatagaaa
     1261 tcaatagcat ccaagatgtt gagccagatt atcaatttca taaagaaggc tgctcggaag
     1321 aagaatcaac cccattcaat gagccgaagc aattttacaa aagggggaaa agtaggggca
     1381 aatctcaacg ctatcaatgt aaggcgtgta agaagttcac taatgttcta ccaaaaagag
     1441 aagaaaccac tacttatcac caacaaaaga acaccattct tccaatgttc gctaagatgg
     1501 ttgttggaag ggtttcagtc agtcgtactt gtgatatttt aggaattgga gttggaacct
     1561 actatcataa gctggagtgg ctgtataggc gttgtttgga gtttttagaa cgatatgaga
     1621 cacaacccct tcaaacaaag aaatttaacg agatgtggct taatacggac aagatgcact
     1681 actacctaaa taacgtccgt aagaaaggac aaggttcaaa gaaatatacg gggtttgaag
     1741 accttaatat gcaaacgtat atagttgtat ctgctgaggt cttatcaaga tatgtgttcc
     1801 gttctgatgt tgcctatgat tggaatattt caatggatga attaaatgaa gatacaagaa
     1861 aattcaaaga agaccatctc aatactttta gtcgtaaaaa tgataggtta gattggtctt
     1921 attatccaca agaaccatcc gctaacgata gcgaaaatag gaatgcttat cttcacgaat
     1981 tagggaaaat tactaatagg agtagatttg tcgatggttt aaatgttgat gctccttata
     2041 ctacaactgc tcactattgg ttaattaaac aaatggttaa tgccgacgaa tggcgaatga
     2101 ttagtgatga tgacttctct attagaaacg ccttttatag agtattcacg aaagaattaa
     2161 ggttgagcga tgcacatcat tttatttgcc aagttaacaa gacgaaaagc agaaaacaat
     2221 gcttaaaaga attcggacaa gcaaaagcag aactgctcga ttggggagat atcagaggat
     2281 tcaaaacaaa gtttctacgg actttggcat ctcattatct aactgaatta ctaacaagtc
     2341 atcaattcca cgaagaggct attagtaaag atggagaaag atatcgcaaa tatgccgata
     2401 accctatcaa acatccatta gccactaagg ataaaggatt ttattcagtt gattgtagaa
     2461 cggatttatc tgctctggaa ccaaacgaaa tcgcaaagat gctattaaat gttaatgacc
     2521 attcgaccaa tagctttatt caacagataa gacgttatat atcatctctt gaaagaccat
     2581 taacaacagc tcgtggtgat aagaagagct atatttacgc taacttcaat ccgaagtatg
     2641 ctcaatttgc gattacaatt ctaagaactt actacaactt ttgtcgccct tttaaatcag
     2701 cggataaaaa ggttttgaca cctgctcaaa gattagggat tacagataaa caatttgatt
     2761 ggaaagatat aatttatttc aaatgacaaa aagagcttgg agtaatccca agctcttgtg
     2821 ctttatcttt actgttcttc ttcaattaac gcacccgtta actcaataag ttttttcttt
     2881 catatacatg aaaatagtag ttatacggat ttttatcatt ctttatccct ttttgggcaa
     2941 atacctcatt ccattcctca taattcactt ctggaaaaaa agtatctcct tcgaattcat
     3001 gatgtatttt tgtgatgtac attttctcaa cataagggaa aaacaaatta taaatctgtt
     3061 ctcctccgaa aataaaaatt tcttcttcgt ttttacataa ctcaaaaaca tcttctattg
     3121 aatgaacaat ttcacaacca ttaaaggtaa accccttatc tctcgtcaga ataatatttc
     3181 ttctgtcagg taaggctctt ccgattgatt caaggttctt cctacctaat attatcggat
     3241 gtccctttgt agtattttta acatattccc agtccttggg aatcctccaa ggaatgtcat
     3301 tctctttgcc aatcactcta ttcttatcca tcgcagcaat caaagaaact ttcatttata
     3361 acacagcctt tttaactaat ttaccatcta atttcttatt tctatcaaaa aaccttttct
     3421 cattatcctg cccgttagtt gaataagcaa ttttttctat aagttatatt atcataatac
     3481 cacaaaatca caaattttca ttcaattatc attttcaatt gcattttata aatcattttg
     3541 tatgtaattt ggtatgtaag ttaaaatgaa aaaagtagtc cattttgaag tacattttgt
     3601 cattttgtac tccaaaactg aactacttac ttgcatatat acgcctttat agtggagtac
     3661 tacatttacg agattcggtt agagtatcag aaaaagaaaa aataaaagtt acagaaatgt
     3721 atacttcaat aaatggtgaa ttatgtaaga ttgatagagc ttattctgga gaaattgtta
     3781 ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg agatacaaaa ctattgccac
     3841 agagaaaaaa gattgaaaat ccgcaccctc tactacaaac aactgttgaa ccgagtaaac
     3901 ctgaacagag agaaatgttg cttgatgccc ttttggaaat ctcagatagt gatccgcttc
     3961 tacgatatta
//
LOCUS       DAIGTA010000122         3867 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.130, whole genome shotgun sequence.
ACCESSION   DAIGTA010000122 DAIGTA010000000
VERSION     DAIGTA010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.130"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(150..1337)
                     /locus_tag="NOB43_002712"
     CDS             complement(150..1337)
                     /locus_tag="NOB43_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HCI0983524.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            1434..1736
                     /locus_tag="NOB43_002713"
     CDS             1434..1736
                     /locus_tag="NOB43_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983525.1"
                     /translation="MDVINETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2249..2322)
                     /locus_tag="NOB43_002714"
     tRNA            complement(2249..2322)
                     /locus_tag="NOB43_002714"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2286..2288),aa:Ile,seq:cat)
     gene            complement(2511..3530)
                     /locus_tag="NOB43_002715"
     CDS             complement(2511..3530)
                     /locus_tag="NOB43_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCI0983526.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(3541..3747)
                     /locus_tag="NOB43_002716"
     CDS             complement(3541..3747)
                     /locus_tag="NOB43_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI0983527.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT         1163 a          778 c          657 g         1269 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact tttacacaat tatatggacg
     1441 taatcaatga gacacaatta tggtttaaat ttgacccttc gaatagattt atcaaagatt
     1501 tttataaagt atggaattca gaagttttct ttttagcaat cgaagatagc ttattaatca
     1561 atctctacta ttctaataag aactatttca aaattcctgc tgcgaaaact agaatgaaga
     1621 aggatgtata ctttttgttt gatatcgtga ctgacgtgcc ggacgcacgt agcgatcatc
     1681 ggcgttatga ctatataaag tatactttcg ttgatccaga aagatacaaa gattaaagta
     1741 ggctacctaa aaaggtagcc cggaacgaat tttatcacca tacttgtgaa aggagatatt
     1801 ttttaagtta gtattaagat tgtgtaatat gatgatatct atattttata gtatcagtgc
     1861 tataaaatca aaaataagtc actaattaac taccactcca attgtaagcc ttttttctca
     1921 ctttttttca aaaatatggt atgcctttta atagcttcaa atataaaaga gtttaaagcg
     1981 taacacactt atggggaagt ggcttggggt gcgctttaaa ctcttcttta ttatcatctc
     2041 acaatttaac ccaaatgtct ttctatttaa aaatcaaagt aaaacttttc aaatatacag
     2101 aaatataact atgtgaaaca tcctttcatt aatccataaa aggatacata aaaaagccac
     2161 tcatttgagt ggcaatgaag aaaagcttta gcttgtataa tactcttcaa aaaattctaa
     2221 cacagaacga ttcaaatggc tacgttaatg taccctgtag gactcgaacc tacgaccgga
     2281 cggttatgag ccgtctgctc tgaccaactg agctaagggt actggttgtt gccacataaa
     2341 gccataaaca atcaaccagt agaatgtgtg gcaacaaacc tgttatcgca tagcttggag
     2401 tgtgactatt atgggtgata gtgaagatat gcgataacat cactatttta tcgaatgatt
     2461 tttatagttg tcaatatagt tatgtaatgc tcctcaacga ggagctattt ttatcgttta
     2521 ggaatattta aataccaacg tttgtcatgg aaatcttgcg caccgccttt agtgtttccc
     2581 tctggatcat tcgttgcccg catcatgaca tagactttct tattagggaa gttacgcatg
     2641 ttaaaagata catgatagcc aacatttcca gaagtattat aagcttgatt tacatctgat
     2701 ctataaattc catcagctct tactcgagct aattctttcc cagtattgta atccataatg
     2761 aagatatact cgtatttata gttagcaatg tgccatccag ctacatgcaa atttgcattt
     2821 tcgatttctc caaactgatc aatgtgggcg taattcgttc catctgtcag tgtaggatta
     2881 gctgcaccag ctcgtgttgg atcaatgaca ggcttgtttt cagaagttgt tggattttca
     2941 tcggtaaatc catgagctaa atcatatgct aatttttctt tacttacgcc catttcagaa
     3001 agataaccgt aaggatctgt atgatcgccc cagatgtttt gtgttaccca taaatgcgat
     3061 ttgattcccg gttggttata aggagtgtcc aacgttaatg gaataccata tttcattgct
     3121 gaatctctag ccaattcaac gtatgccttg tagtttttct caaacgttgc tttatcatgt
     3181 gtgtgttgta actcaatctg cacaggactg ttggcattag catacgaacc agcaccgtac
     3241 tgtacataac caggttgacc gacttgataa acaattccgc cgtctcccac aatataagca
     3301 gtataagcgc tagtccatga acgttgcata tactgcgctt cattgcgtcc tgttgctgtt
     3361 tcattagccg tttcatgcag taaaatatac tgattatttg ctacttgtga gctaccttca
     3421 tttgcgccca aattaaattc attgttgata gtataggcaa atccgttaat tggcaataaa
     3481 aaaagagccg ttaacaggct catcgcagta atagtaattt tctttttcat atctatcctc
     3541 ctatttatct gatgaaattt tcttatacgt tcgatttgat acacctaaaa tactccctag
     3601 aaatgctcca aaacctgtaa taatcatcac cgttatatct gtgtaccgcc agttaacacc
     3661 ttttccgaca agaccgacaa aagtcgctaa agcggggata actactatag cgatccattt
     3721 caaaatatca aaggttctat tgttcatact atccacctcc cttcattggt tgggctactt
     3781 tctttttcaa tcgcttgttt tcttctatca atatttctct ttctgaaagc aaggcatcaa
     3841 tttgcccgtc cagttgttca attttat
//
LOCUS       DAIGTA010000123         3790 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.131, whole genome shotgun sequence.
ACCESSION   DAIGTA010000123 DAIGTA010000000
VERSION     DAIGTA010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.131"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..411
                     /locus_tag="NOB43_002717"
     CDS             <1..411
                     /locus_tag="NOB43_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983528.1"
                     /translation="GLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAP
                     QEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLT
                     ELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            521..571
                     /locus_tag="NOB43_002718"
                     /pseudo
     CDS             521..571
                     /locus_tag="NOB43_002718"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            605..1981
                     /gene="tet(L)"
                     /locus_tag="NOB43_002719"
     CDS             605..1981
                     /gene="tet(L)"
                     /locus_tag="NOB43_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCI0983529.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2576..2887
                     /locus_tag="NOB43_002720"
                     /pseudo
     CDS             2576..2887
                     /locus_tag="NOB43_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            3022..3669
                     /locus_tag="NOB43_002721"
     CDS             3022..3669
                     /locus_tag="NOB43_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HCI0983530.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT         1254 a          507 c          697 g         1332 t
ORIGIN      
        1 ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc tcctattgta
       61 ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa atattgtgcg
      181 aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga aatccctgct
      241 cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg tagtgtttgt
      301 ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca gccccgtcgt
      361 ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta gtgtatttta
      421 tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta ataaagattt
      481 gaattaaagt gtaaaggagg aattaattat gaagtgaaat gaatgtaaca gggttcaatt
      541 aaaagaggga agcgtatcat taaccctata aactacgtct gccctcatta ttggagggtg
      601 aaatgtgaat acatcctatt cacaatcgaa tttacgacac aaccaaattt taatttggct
      661 ttgcatttta tcttttttta gcgtattaaa tgaaatggtt ttgaacgtct cattacctga
      721 tattgcaaat gattttaata aaccacctgc gagtacaaac tgggtgaaca cagcctttat
      781 gttaaccttt tccattggaa cagctgtata tggaaagcta tctgatcaat taggcatcaa
      841 aaggttactc ctatttggaa ttataataaa ttgtttcggg tcggtaattg ggtttgttgg
      901 ccattctttc ttttccttac ttattatggc tcgttttatt caaggggctg gtgcagctgc
      961 atttccagca ctcgtaatgg ttgtagttgc gcgctatatt ccaaaggaaa ataggggtaa
     1021 agcatttggt cttattggat cgatagtagc catgggagaa ggagtcggtc cagcgattgg
     1081 tggaatgata gcccattata ttcattggtc ctatcttcta ctcattccta tgataacaat
     1141 tatcactgtt ccgtttctta tgaaattatt aaagaaagaa gtaaggataa aaggtcattt
     1201 tgatatcaaa ggaattatac taatgtctgt aggcattgta ttttttatgt tgtttacaac
     1261 atcatatagc atttcttttc ttatcgttag cgtgctgtca ttcctgatat ttgtaaaaca
     1321 tatcaggaaa gtaacagatc cttttgttga tcccggatta gggaaaaata taccttttat
     1381 gattggagtt ctttgtgggg gaattatatt tggaacagta gcagggtttg tctctatggt
     1441 tccttatatg atgaaagatg ttcaccagct aagtactgcc gaaatcggaa gtgtaattat
     1501 tttccctgga acaatgagtg tcattatttt cggctacatt ggtgggatac ttgttgatag
     1561 aagaggtcct ttatacgtgt taaacatcgg agttacattt ctttctgtta gctttttaac
     1621 tgcttccttt cttttagaaa caacatcatg gttcatgaca attataatcg tatttgtttt
     1681 aggtgggctt tcgttcacca aaacagttat atcaacaatt gtttcaagta gcttgaaaca
     1741 gcaggaagct ggtgctggaa tgagtttgct taactttacc agctttttat cagagggaac
     1801 aggtattgca attgtaggtg gtttattatc cataccctta cttgatcaaa ggttgttacc
     1861 tatggaagtt gatcagtcaa cttatctgta tagtaatttg ttattacttt tttcaggaat
     1921 cattgtcatt agttggctgg ttaccttgaa tgtatataaa cattctcaaa gggatttcta
     1981 aatcgttaag ggatcaactt tgggagagag ttcaaaattg atcctttttt tataacagga
     2041 attcaaatct ttttgttcca ttaaagggcg cgattgctga ataaaagata cgagagacct
     2101 ctcttgtatc ttttttattt tgagtggttt tgtccgttac actagaaaac cgaaagacaa
     2161 taaaaatttt attcttgctg agtctggctt tcggtaagct agacaaaacg gacaaaataa
     2221 aaattggcaa gggtttaaag gtggagattt tttgagtgat cttctcaaaa aatactacct
     2281 gtcccttgct gatttttaaa cgagcacgag agcaaaaccc ccctttgctg aggtggcaga
     2341 gggcaggttt ttttgtttct tttttctcgt aaaaaaaaga aaggtcttaa aggttttatg
     2401 gttttggtcg gcactgccga cagcctcgca gagcccacct ttacgaagta aagtatagtg
     2461 tgttatactt tacatggaag ttgtaccgaa atattgtgtt gtgaagtcta tataatttta
     2521 aaattatgaa gtctatatac gtgcgtaaag atatttaaag agattaaaaa taataaaaat
     2581 aaaaattgaa ttaaaaagag atatggttga ttattggaac gattgtttta atgatttaca
     2641 tatattacaa ccagattgga aaactatcga acgtacttct gatagagcaa tggtttttat
     2701 gttgttgaat gatgaagaag aatggggaaa attagaaaga cgtactaaga ataaatataa
     2761 aaaattaatt aaagaaatat ctctaattga tttaactgat ttaatgaaat cgactttaaa
     2821 agcgaacgaa aaacaattgc aaaagcagat tgatttttgg caacgtgaat ttagattttg
     2881 gaagtaaagt aactttgttt tatacaaaat gttactttag tataattaac gtttaagagg
     2941 tgacacaata tatgaaaaaa tcagaggatt attcctccta aatacaaaga gataagatga
     3001 aatttaggag gaaaattata tatgactttt aatattatta atttggaaac ttgggataga
     3061 aaagaatatt ttaatcatta tttcaatcaa caaacaactt acagtgttac taaagaattt
     3121 gatatcactt tacttaaaag tatgataaaa aataaaggat atgaactgta tcctgctttg
     3181 atttatacaa ttgtaaatat tataaatcaa aataaagtat ttagaacagg aattaatagt
     3241 gagggaaatt tgggttattg ggaaaaatta aaccctttat atacagtctt taataaagaa
     3301 actgaaaaat tttctaacat ttggacagaa tcaaatgtta gttttaattc tttttataat
     3361 agttataaga gtgacttact tgaatataaa gataaaaatg aaatgtttcc taaaaaacca
     3421 atacctgaaa acacagttcc tatttcgatg attccttgga ttgattttag ttcatttaat
     3481 ttaaatattg gtaataatag tagattccta ttgccaatta ttacaatagg taaattttat
     3541 agtaagaata ataagatcta tttaccagtc tcattgcaag ttcatcatgc ggtatgtgat
     3601 ggttaccatg tttcattatt tatgagtgaa tttcaaaata tagttgatag tgtaaatgaa
     3661 tggatttaaa tctaaaataa ctttcataaa cttaagtaat tatgatattt ataagtttat
     3721 agcaactacc atttttggtt gctggtgttt tgattttgaa tttggttttg aacttatgga
     3781 ctgatttatt
//
LOCUS       DAIGTA010000124         3666 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.132, whole genome shotgun sequence.
ACCESSION   DAIGTA010000124 DAIGTA010000000
VERSION     DAIGTA010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.132"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(130..429)
                     /locus_tag="NOB43_002722"
                     /pseudo
     CDS             complement(130..429)
                     /locus_tag="NOB43_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
     gene            617..1786
                     /locus_tag="NOB43_002723"
     CDS             617..1786
                     /locus_tag="NOB43_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0983531.1"
                     /translation="MNDFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            2091..2783
                     /locus_tag="NOB43_002724"
     CDS             2091..2783
                     /locus_tag="NOB43_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0983532.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKIHNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            3211..3603
                     /locus_tag="NOB43_002725"
     CDS             3211..3603
                     /locus_tag="NOB43_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983533.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
BASE COUNT         1430 a          470 c          569 g         1197 t
ORIGIN      
        1 taaaatcttg atttaactag tttttttctc tcgtcttttt tatagatatg tataccttcg
       61 aaaagacaag aaataaaata gaaatacctg tttagtgcaa aatgagaaga atctttttta
      121 attcatagtt tataatttat ggatttctga tttagtcgta ggtgcatttt taatggtatc
      181 agctaccgga caagtacgat caataaatgc gataaaatct gaaatctctt catcagtatt
      241 atcagcttca atataaaatt tagatacgat tgcagaatag cctattttag ctgctttatt
      301 ttttcctata aaaccatcag gatctaatac tccatctatc tctacacgga tatcgtttaa
      361 atttatgccc tgcactttag cgaaagaccg agctacaata actttacatg ctccaagaga
      421 ggctaataat aagtattgga gatggtgcga agtaagattg ataaaaaatg gataaaggat
      481 tagatttaat acaatgtctt atcacgattc taatgatttg atgagagtgt aaaatatttt
      541 gtgtaaatag aaaaaaggaa gtcccttctg tagaatagag ttaccacaac acattcacag
      601 aaaagaggac ttccatatga acgattttac tacagaaatt atggaaacac taatcaataa
      661 aggtgattta gatgaattat ttcgatgtca tttagaatta gctgttaatt cattattgca
      721 ggctgaatta acagcttttc ttgattatga aaaatatgat cgtgctgggt tcaattcagg
      781 taattcccgt aatgggaatt attcacgttc attcagaaca gagtatggag aattaaattt
      841 ggtgattcct agagatagaa atggtaagtt ttctcaacaa actttacctg cttataaaag
      901 aaccaatgac tctttagaaa ccactattat tcagctattt caaaaaggaa ttactatgtc
      961 tgaaatctct gaattgattg aaaaaatgta cgggcatcac tatacgccac aaaccatttc
     1021 aaatatgact aaaatagttt ctgaagatat tattgccttt aaagaaaggt ccttagaatc
     1081 cagatactct gttattttta tggatgctac tcacattcct ttaaaaagac aaactgtttc
     1141 aaaagaagca gtttatattg taattggcat tcgattagat ggaaccaaag aggttcttgg
     1201 gtttagtctt gctccaactg aatctgctta tgtttggaaa gagattcttc aagacctaaa
     1261 agaccgtggt ttaaaagagg ttttattagt cgtaactgat ggtttaagtg gcattaacga
     1321 tagtattcat agtgtttatc caaatgctca atttcaacaa tgttgtgtcc atatatctag
     1381 aaatatcgct cataaggttc gtgttagtga tcgacaagaa atctgtagcg atttcaaatt
     1441 agtttatcaa gcaagttcaa aagaagaagc aaataatcaa ataaggttta tgatagataa
     1501 atggaaaaag cagtatccac gagtggttaa attgctcatg aatcctgcta tattaacctt
     1561 ttataatttc cctccgtcaa tcagaagaac tatttattca actaatttga ttgaaggttt
     1621 taacaaacaa ttaaagaaat ataccaaaag aaaagagcaa tttcctaatg aagaatctct
     1681 ggagagattt ctagtatctc aattcaacaa ctataatcaa aagtttctat gccgagttca
     1741 taaaggtttt aaagaaatac atgatacatt agaatcaatg ttttaacttg atcaacagaa
     1801 tgggcttttc catttacaca taattcttga cgcaacctat tctggaaact tacaaataaa
     1861 agcttattct tcagccacct tcgggtggtt attttttata aaaaaatgta aaaaaatatt
     1921 gatacataaa taaattagtt gtagtaaata gttttagaat tgaatttctc tatccttttt
     1981 aaataatttt ttagacaaaa aacagaaagt gtctaaagaa agcttgacga agaaaataat
     2041 ttttaataac ttatttaagg taagaaaatt ttttgaagga gaagataaaa gtgagaaaaa
     2101 agattattat taatgctgga gtaattatag gattgatgtt agtaattttc tccggaaagc
     2161 aatatgctga taatatttta ttatggggag gggaagataa tattgaaaag atccacaaca
     2221 atttaactat attagacaca gctctagaaa ataaagagca aaaaattagt attttaaatt
     2281 cacaattgtc ttcaaacaac caaactcttg aacaactaag aactaatatt gaagtttcca
     2341 aacaaaaagt ggcatcttta gaaaacgaca agaatcaatt agtatcagag aaaactaatt
     2401 tagaaaatca attgtcagca aaagactctg aattgcaagg aaaacaaaat gaaattaatg
     2461 cgaaaataga cgaaattaac caaaaagtag ctgaaataaa tcgattaaat agcgattgga
     2521 ataatcgttt acaaaatgaa aagaacaaat ttaatgaaga acaatctact attaatagtt
     2581 taaaccagca aattaatcaa atgttgagtg aaaaaaataa cattcaaaat caactgcaag
     2641 ctactcagca aaagctagaa gaagaaaagt caaaaaatag tagtttgaat aattacattg
     2701 aaaagcttca aaaagctaaa aatgatgtag aggataccgc aaataaagca caacaaattg
     2761 taaatgaaca tacaatccaa tagatatagt tttaatttaa caaatggtat gtttggagat
     2821 aatgagatag aatataaatg tcataatatt atacaatcta aacaccgttt ccttttctat
     2881 ttttgatgac atcagtatat agctactcga aagagtagtc tttttattat tctcgcttat
     2941 tattgatatg aaaatttcga tttgacaaaa ggtaccgaat aattttgtaa tatgaattat
     3001 tatcaagaag taattatgat gataacatat ggaaactagt tagtaataat cacaggtgat
     3061 taaacttttg aacgacttgt aattctatat tttttctttt aagtaaaaaa tataggtgag
     3121 tttttttgac ttcatattta taataaagac acgtaaatca attatttttc attttacttt
     3181 aactaataat gtttatttgg agggattatt atgttagatg atagattgac gtgttctaat
     3241 tgtggtacat tattttacta tgaggaagtt agaaatattg taaaacatag aaaaaaagaa
     3301 atgcctatac gttgtccaaa ttgcaatgaa gttattaagc gaaagttgtc tcatggttat
     3361 tttgtcagct acgaactata tgaagaaagt aaaataaatc tgaaaaaaaa accaaaatac
     3421 tataaaaatt tgaaaactgg agctattata actgaaaaag aatttaaaaa tttagtgact
     3481 gaagaagaaa gcaggtttta taatttgtct ggtaatattt gccctggatt tatggatcag
     3541 attattgaaa atgagtcaat tgaatcaatt gaaaactatg ttcctgttga cttaccaaaa
     3601 tagaaaaaat aatcctgttt ttacagtgaa ttattttaat tttgattttc aataaaaata
     3661 tattac
//
LOCUS       DAIGTA010000125         3650 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.133, whole genome shotgun sequence.
ACCESSION   DAIGTA010000125 DAIGTA010000000
VERSION     DAIGTA010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.133"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            164..715
                     /locus_tag="NOB43_002726"
     CDS             164..715
                     /locus_tag="NOB43_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HCI0983534.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1391..1645
                     /locus_tag="NOB43_002727"
                     /pseudo
     CDS             1391..1645
                     /locus_tag="NOB43_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1715..2227
                     /locus_tag="NOB43_002728"
     CDS             1715..2227
                     /locus_tag="NOB43_002728"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983535.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2224..3261
                     /locus_tag="NOB43_002729"
     CDS             2224..3261
                     /locus_tag="NOB43_002729"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0983536.1"
                     /translation="MISFSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
     gene            3421..3597
                     /locus_tag="NOB43_002730"
                     /pseudo
     CDS             3421..3597
                     /locus_tag="NOB43_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT         1331 a          623 c          722 g          974 t
ORIGIN      
        1 aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt attgggaatc
       61 ccagcttaaa tcatagatac cgtaagggat tttattcttt atttaaaact ttgcaacaga
      121 accgaagagc gagcaagaca ggaacgagag aacaaacata ctcatgaaaa gactagaggc
      181 ttcgacctcg aactttaata ataagttaga tgtttttgaa gaaaagacta agcatgcaag
      241 attaaacttt gaaacaactg caaagcacta tattaaacga cttgatgaag ataatttgaa
      301 attagatttt caacaagcta ttcaagatga attaagcgat actaaagacg aaatacgtga
      361 agtgacgaaa caagcgagag aagaaacaaa agagtataaa gaaatcttag aaagtaaaat
      421 aaaagaccat aacaaagtgg ttgataaatc gaatacagcg ctaaaagtga tgacaaaagg
      481 cgttacaaat atattttttg tgctaattat ttttgtactt gtaatgcttg tgacaggtcc
      541 gataggtcat ttctttggta ttgaacattt atatagcttt attaatggtt ttattgatga
      601 ccacgaaagt gcatggcgat atttgatgtt gatactttat gcagtaccct atgtattctt
      661 cgctatcatt ctgtggctca tagcattgtt ttttagagta tttaatgacc tttaggtaga
      721 tttatatata aaaagggcta aatacgcaaa ataccccctt aaaatgcaaa ataaatgcaa
      781 ataagggggt aactccttat gaaaaaacaa ctaatagtat tataacacgt ttttatgccg
      841 agaaaactta ttggttggaa tgggctatgt gttagctaac ttgttagcga gttggttgga
      901 cttgaattgg gattaatccc aagaaagtac caactcaaca acacataaag ccctgtaggt
      961 tccgaccaat aaggaaattg gaataaagca acgaaaggag ttgagtaaaa tgagtgagaa
     1021 aacgaagaaa atcattcgag tatcattagc tttttcacaa gtagtagtgc aatcattgat
     1081 agtttattat acttaccagc aatataaatt atctaaagag aattaagttt tgattatgta
     1141 ataagttttg gtactaaaaa agacttgatc taattagacc aagtcttttg ttagtgttat
     1201 attaataaca aaataaaaat aagaagtcgc tcactccccg accaaagttt gtgagcaaaa
     1261 taaacagtcg atgtttgttt cttaattgta tatcttgata ttaaacgatt taagattatt
     1321 cttcaagata tatattcgca aatgtaattg gaaaagcgac ttcttaaaca aaattaagga
     1381 gtcgcttttt atggcaaaaa taacgaaaaa tgagcaagaa aatttggtgg aaaattacac
     1441 aaaaaaaccg gcgtactcta atagccggtt agacgcacat ttcgtgtgca cttctaatcc
     1501 gaaattgagc tttgacgcta tgacgatagt cggaaacctt aataaaaaca gcgctaaaaa
     1561 gctatccgat tttatgagtt tagatccaca aattagactt tgggatatac ttcaaacaaa
     1621 atttaaagct aaagcactac aagaccccct atgttaggct agttgtcgta taggataata
     1681 agttataata aagactatac ggaggatgat taccatgaca aataaaaaca atgaacgtta
     1741 ctctaccgaa ctgaaagcga cagccatcaa gaaaatgatg ccacccgaaa atagggggat
     1801 tcgccaatta agtcaaactt tgggcattcc agaagcgact ctttgttctt ggcgtaaaaa
     1861 agctagaatt caagggaata ctacacccgg aacgaaaaaa aatgtcgaaa aatggtcaag
     1921 tgaagataaa tttttaattg tgatggaatc attctcaatg aaccaagtag aacttgcgga
     1981 atattgccga aagaagggct tatttaaaga acaaattgag gcttggaaga aaacgtgctt
     2041 atctgcgaat gaacaggaag aaaatcgaac gagagaactt gcaactgaac taaaagaaga
     2101 gaaaaaacaa gcgcgtcaat tagagaaaga attacgtcat aaggaaaaag cattagcgga
     2161 agccgctgct ctcttattac taagaaaaaa agcacacgcg atttgggggg accaagagga
     2221 agaatgattt cattttcaga tcgcaaacaa gctgttgaac ttattcaaga agccaatcgc
     2281 aatggggccc gtctcaccta tgcctgtaat gagctgaata ttagcgttcg aacctacgaa
     2341 cgatggacgc gtgaaggtac gatagcgcat gatcaacgcc ctttggcgaa acgtcctgta
     2401 cccaaaaata aactgacgga tcaagaacgc gaaaaaataa tagaaaccgt ttcaaaaaaa
     2461 gaatttatga atttgccacc tagccaaatt gtaccaaaac ttgcggattg ctcgatttat
     2521 attgcatcag agtctagctt ctatcgtgta ttgcgagaaa aaaatatgca acatcaccgt
     2581 ggccgaagtc aagtttcaca aaaacgcata ccgccaagtc accttgcgac gaagccaaat
     2641 gaagtttgga cttgggatat tacttggcta aaaggtccaa taaaaggact cttttaccgg
     2701 ttatatctca tcattgattt atttagccgt aaaatggtag gctgggagat ttgggaatca
     2761 gaagaagctc gtcatgccga aaaacttatt aaacagacgg tgcttaagga acgtatccaa
     2821 ggacagccgt tggttttaca ctccgataat ggcagcccta tgaaagccgc gacttttcaa
     2881 gtcttactcg aaaaattagg aattcaaagt tcttattcaa gaccacgagt gagtaatgac
     2941 aatccttatt cggaagcggc tttccgaacg ttaaaatatc gaccagaata tcccaataac
     3001 ggctttaaaa caatagatga tgctcgaaaa tggacgaaag agtttgtcga ttggtataac
     3061 gattctcatt tgcatagtgg gattcaattt gtgtctcctg cagcgtgtca tgaaggacga
     3121 catctcgcta ttttagagaa acgaaagcag gtttacgagg acgctaaaaa gcgccatcct
     3181 gaacgctggt caaaaggtgt tcgaaattgg actccacatc aatcggtggc gttgaatcct
     3241 ttaaaagaaa cagaaagtta acaggagcat aatctttcaa gattatcaaa taaccctcgt
     3301 cacccaatag gggaaaaagt tattcttccc ctattggata acgaggccaa ccgaccatag
     3361 ggaggttctg ctttttgata ggtggaaaat aaaaatacga caactatatt gacaaacacc
     3421 gaccatcgtc cagtaaagag acgcaataaa ttctatcgaa gtttacgcac tgcctctaca
     3481 acgattaaag gcatggaagc catccgagga ttatataaga aaacccgaaa agaaggcact
     3541 ctcttcgggt tttcggtctg tactgaaatc aaggtattat tgggaatccc agcttaaatc
     3601 atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac
//
LOCUS       DAIGTA010000126         3351 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.134, whole genome shotgun sequence.
ACCESSION   DAIGTA010000126 DAIGTA010000000
VERSION     DAIGTA010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.134"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(268..438)
                     /locus_tag="NOB43_002731"
     CDS             complement(268..438)
                     /locus_tag="NOB43_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983537.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(454..990)
                     /locus_tag="NOB43_002732"
     CDS             complement(454..990)
                     /locus_tag="NOB43_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI0983538.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTPILSEET
                     ESIEKHTKKKQKWWQLWK"
     gene            complement(1011..1955)
                     /locus_tag="NOB43_002733"
     CDS             complement(1011..1955)
                     /locus_tag="NOB43_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HCI0983539.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            2592..2678
                     /locus_tag="NOB43_002734"
     CDS             2592..2678
                     /locus_tag="NOB43_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCI0983540.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(2799..>3351)
                     /locus_tag="NOB43_002735"
     CDS             complement(2799..>3351)
                     /locus_tag="NOB43_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983541.1"
                     /translation="IFYLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKE
                     QALAQKMEEFTTCYEEMNDIFVNQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQV
                     KKDVQYVKDTKVEEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQATNIQNP
                     TKKETALNYLKSVKEWLDQQQQN"
BASE COUNT          901 a          610 c          555 g         1285 t
ORIGIN      
        1 tatgccaagt agcccttgta tcaaccgata caggggctca ctttgtgatt ttggattggt
       61 ctaggtaaaa agctcttttt aaggcttgat tttctgcagt tgcttctttc cgtttctttg
      121 tgaattttta ccagtcattt tttactgggt tgttattttt cataaaatat gataaatttt
      181 tggtagcgct ttataagtgc gctgcttttt caagaataaa ctctcattat ttttttaact
      241 ggctgctcga aaaagcagtc ttttttatta tttatccgtt tcttttacaa acaattcttc
      301 gttaggactg ttgtaataat ttggattcaa tttcaattca ccatgtttat tccctttatt
      361 gatcactgac aataacatcg gactgaatcc tagaattcct agtaaaatag aaccgaatag
      421 aagatttttt cttgtcatga atgttccctc cagttatttc caaagttgcc accatttttg
      481 cttctttttt gtgtgttttt ctatcgattc tgtttcttca gaaagaatag gagttgattc
      541 atcttctgga gtttcttccg tataagctaa ttgtaactgt tcttgcaatt tttcgatctg
      601 ttgatttgcc tgtagggtga gctgttgttg ctggtcgagt aatttttgca tattagaatt
      661 attttgctct ttgagggcaa gttgttctcg taaaaattca ttttcttcac gcaactgatc
      721 tagcaacttg tttgcaacca cgtttttgtt tggtatataa gcatttttat cgttgttttg
      781 ttcatgttta tgcaacttat ctagcaacct ttgattgtct aagttgcgag caagttgcaa
      841 tactccagaa cgcaatacaa ccttataacc acgctcattt ttagctatca tggaagaatc
      901 taatttttgg atatgtttcg atattgcttg cctactcatc ttaaaaagat ctgacaattc
      961 ctttattgta aaggtttctt gtggttgcat actggttgcc tcctaggttg ctactggaat
     1021 aaattatcta aatcagataa taaacttttt ttctcttttt ccgaaagtgc ggactctgtt
     1081 tgtttttcaa gagctttttt ctctttttct agttgtttga tttgttggag gagttcaagt
     1141 tctcgtttct tctgtttgat tttttcgtta attgttgtag cgggttcttc gtattctttt
     1201 tgtttatcag ctaaagccaa tgctttattt tggtcttctt tggttggtgc atgtttgtta
     1261 aagtcgtctg cttttttgat ctcaggtttg aacgtaaatt gatagccaat aacaggtttt
     1321 ccccgtcctt ttccgtattt ctttttgatt gttagtcctt tgaagattgc agttagttct
     1381 tgacgtatag gttttataac tcgtttatct atatcaggtt gcttataact tttaggaata
     1441 tctaataatt caagaaagtc ttctttggag aaatatgcga aacctttggt tctgtattgc
     1501 tttaacagac gaaacatagt ctttgcatag ccactttgta gctcgttgaa ttgttgtaaa
     1561 gaatagcgta cccactcgtc taaattattt aacaaaggca gtgctttttc gtaaattcgt
     1621 atatctacgt aaggattttc tacgtccccg ttgattttaa attctgtaaa cattacaaac
     1681 atatcgtaag aaagcccaga ctcacttcta cgaccaaagc gtaaagataa gattttttca
     1741 taagttgctt ttaaatcttc tacaaatcgt acatttgcag ttgctttgta gttacttaaa
     1801 tcttttagtt ggtcaaacgt aaaacgaact gtcttatccc ctttttcacg cattctagac
     1861 acgatggaaa aaaacaaatt catttcaacc ggtgtaaatt ttcttaaagg aattgtattt
     1921 aattcatggt ggtattttac aatctcatta gccatataat cacctcaatc caattatgaa
     1981 tgacattttt taaatgtcaa gacattcata tttgacgttc aaacagacaa aatgtccttc
     2041 ataaacagac aaaatgtcct tcataaacag acaaaatgtc cttcataaac agacaaaatg
     2101 tccttcataa cattctgtat ccattggtag agtaaggaca cagcttacgg taaagaggtt
     2161 taaaaagagg tttaaaaaga gatataaaaa gaggggggct aattttcccg cctaaaaacc
     2221 acttcttttt tctttaaaca ggttcgcgca tttttcaaaa ctgccaatcc aaaaccttgc
     2281 ttcctacggt cgccaaaaag gtgtgatcgc tacgctctca cattgtactg cgcagtcgcc
     2341 taaaggctcc tttgctaaaa acatgttggt aaagaggcct ttgagcggtt ctgaatgctt
     2401 atctaagccg ttttaagaca gtcttggata aaaatcctta tctagcttta aagcgcctta
     2461 caggcggtca gggcaagccc taacaaccct aaaataagcg atacttaaaa acaccacaca
     2521 agtttaattt tttaagatat aataacttgt cgcctatccg acagtcttgc gactggaagg
     2581 aggtgtatct aatgtttgaa ttgttcattt gcccccttct tatagaagtt tgtgtctctt
     2641 tattcagtta ttggttgaat aaccgaaaca agaagtaaaa tcaataaagg cgacatcaac
     2701 ctgaaaaaaa gccccagaga atccgacctc tctggggctt tcgtgtatct aatgtttgat
     2761 catttgcatg tttagtttaa catgattgcc gatcaaattc aattttgctg ttgctgatct
     2821 aaccattcct tgacactttt tagataattt aatgccgttt cttttttcgt tggattttgt
     2881 atgttcgttg cttgttgaag caagatttca tagcgttcat atgtgactga ttgttgtcgt
     2941 tcttttcgtt cttgttcgct agttgaaaaa ggaattgtat ctccaaataa atcactacaa
     3001 gcttcttcca ctttcgtatc tttcacatat tgcacgtctt tttttacttg ttcatatttt
     3061 tcttggtact ctttttgctg ttcttctggc aaattccgat aaagtcgagt gagtgtttcc
     3121 atatttttat ccgtcaaacg tttttcttga ttcacaaaaa tatcgttcat ttcctcataa
     3181 caagtggtaa actcttccat tttttgtgct aatgcttgct cttttttctt tttatcacgc
     3241 gctgattcat acttttgagt gacatttcct aataaaatac ttctagaaac gcgcttattt
     3301 ccctctaaaa cgccgaataa gccgcttgaa acgattatca agtaaaatat a
//
LOCUS       DAIGTA010000127         3219 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.135, whole genome shotgun sequence.
ACCESSION   DAIGTA010000127 DAIGTA010000000
VERSION     DAIGTA010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.135"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            50..1438
                     /locus_tag="NOB43_002736"
     CDS             50..1438
                     /locus_tag="NOB43_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HCI0983542.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3219
                     /locus_tag="NOB43_002737"
     CDS             1776..>3219
                     /locus_tag="NOB43_002737"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCI0983543.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1183 a          505 c          583 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaag
//
LOCUS       DAIGTA010000128         3172 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.136, whole genome shotgun sequence.
ACCESSION   DAIGTA010000128 DAIGTA010000000
VERSION     DAIGTA010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.136"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            12..3161
                     /locus_tag="NOB43_002738"
     CDS             12..3161
                     /locus_tag="NOB43_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HCI0983544.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1124 a          540 c          675 g          833 t
ORIGIN      
        1 agggaagata aatgaaaatt agtcaccgtg aggaagcgga agtcgaagaa cagttgatcc
       61 gtgtattggg ggaagggcat aatcagtgga cgtatcgtcc cgatctaaaa tcagaagaag
      121 atctttgggt caatttacgc caaaaaatca tctcaaataa tcaagcagaa ctgaatgatt
      181 ttcctttgac cgataaagaa tttgaaacga tcaaaacaga attgttacta cgaacgaaaa
      241 ccccctttga tgctgcgaaa tggttaaaag gtgaaaatgg aatggctcgg atcacgattg
      301 aacgggaaga tccgcaactg ggttctgtct cgctcattct ttattctaat caagacattg
      361 gtggaggaat ctctacctat gaagtggtcc atcaaattgc aaaacgtgga agtaacatag
      421 aagcacggga tcgacgtttt gacgtcacct tactgatcaa tggattaccg attgtccaaa
      481 tcgagctgaa acaagtaacc gcaaaagata gtttttatca ggcgtttaac caaatcaaaa
      541 aatatgcaga agaaggtatg tttcggaaca atatcttttc gaccttacag ttgtttgtgg
      601 tttccaatga acaaaccact cggtattttg caaatgcctt accaaaggat ttgcatccta
      661 agtttttatt tagttggcga acgaaagata ataaaaaggt agaaaactta tatgagtttt
      721 gcaaacaagt gctaaatatc ccggatgctc atcgcttgat tgcggattat acgattgtca
      781 gtgaagatca agacaataaa atcctcatgg tgttacatcc ttatcaagta catgcgattc
      841 aagccttgtt tattgctgca aataaacatc aatcaggata tgtgtggcat gcgactggtt
      901 caggaaaaac gttgactagt tttgtatcta ctaagctttt agcacgaaaa tcggggatcg
      961 atcggacgat catgttagtg gaccgcaaag atttagataa tcaaaccacc acagagttta
     1021 cgaaatttgc ttcggaattt aatactggga tttcttccgg gaacgccaaa gcgaatagct
     1081 tgatcgtggg aacaggaagt gccaaagagt taagtgaaac tctgttggca gatgccaatg
     1141 caaatgttgt gattattaca acccgtcaaa agctagatgc ggcgttgaaa tatgcaaaaa
     1201 aacaagaaga gaaaaaagga accaatcgct tccaaaaatt aatggggcaa catatcgtgt
     1261 ttgtagtaga tgagtgtcat cgagcgttaa gtgctgaaaa tatggaagaa atcaaaaaaa
     1321 tgtttccgaa atccacttgg tttggcttta caggtacacc gattttccct gagaatcgga
     1381 aacaagccaa agggcaattg gcacgtacga cccatgatca gtatggagag gtcttgcata
     1441 cctataccat caagaatgca ttagaagatg gctcggtttt aggatttcaa gtagagcatg
     1501 aaaacaccgt ggagccgact tcattagaga ataaaatcta tcggaaatta aaagaagtag
     1561 aaacatatgc agagtattca ccggaacaga tcaatcgtat gattgatcaa atggagcctg
     1621 tcaaaaaaga aagttatttg gaccctactg tttttgaagc agatgaacat atccaaaaag
     1681 tcattcataa aatgttccgt ccagacaatg cctatacaaa atttgatttt cgaaatggcc
     1741 gtccaacgaa gtctgcgatc ttaaccacga gttccattga catggccaaa aagtattatc
     1801 gagcgatcaa agaaatgacg aaagaacctg actggttaac aaaagagttt cctaatcagc
     1861 ccattcgtga aggaagaacg atggaggatc ctgattttcc acgaatcgct attacctatt
     1921 cattagaaga aaacagccga gattcaagtg tccaacaaga agaaatgcaa aaaattattg
     1981 aggaatataa tcagtattat gatacttcct ggtcattagc agacattgag cgttataacg
     2041 gagacatcaa taatcgtttg gcacgaaaaa gagcggaatt caaacaattt gggaaacaaa
     2101 ttgatttagt gatcgtagtg gatcgtctat tgacaggttt tgacgcacct acgattcaaa
     2161 ccctatttgt ggatcgtaat ctagagtatg caggattgat ccaagctttt tcacgtacga
     2221 accgtacgta tccagaaaaa acaaaaggac taattgttac tttccgaaag ccagccacaa
     2281 tggagaagaa tgtcgaggat gcgacaaaac tgtattcaga agcaaaagaa gaatcgggtt
     2341 tgatttatcc aagttatcag gaatccaaaa aaagattcaa gcaagcatat ggtaagttaa
     2401 aagaggtttc atccatggaa tccattgatg aacatacgcc acttgaaatc cgtatcgagt
     2461 acgtcaaagc attccaagaa ttgaatcgtg cttatgaatc gttagtgact tatgacgatt
     2521 acaatgatga catggtgaaa tcttcaacct tgaacaatca aattcaactt ttggaagaac
     2581 aaattggcgt gtacgagacc gtgaagggtt cattaataga ggaagaacca gaaaaagagg
     2641 gagaagattt ttccacgatc gaattttata gtgaaaatac cacgaagttg tatgatattg
     2701 attctactta tattgatcaa ttactaggaa cttatgcggc gaatagttca gatgcacgag
     2761 aagaaattga aaaagctttg gctaaattga ataaaacaga aggagtcaaa gaagtttacc
     2821 gacaaatttt aaatgcgttt gatgtgggga ctttagatag taatgaagat atctttgtca
     2881 ttaaacgtcg ctattttaca caagcgagtg atgatttgat tcatgtcttt tccaatgagt
     2941 ggtttgtttc tgagaaagaa ttacatgctt ctaatctgca atatatgcca ggtgaagatc
     3001 caattcctaa tatgaaagca attatcaaca gtaaggatta cgaaggatat aaagccaacc
     3061 atccagaagc gaagccattt aaatacccac aagaaatgaa gcgagcatgg cgtaaaatgt
     3121 tagatgatga gctgattcca cttgaaaatg aattgaggta aacgagaaga gt
//
LOCUS       DAIGTA010000129         3022 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.137, whole genome shotgun sequence.
ACCESSION   DAIGTA010000129 DAIGTA010000000
VERSION     DAIGTA010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.137"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(287..649)
                     /locus_tag="NOB43_002739"
     CDS             complement(287..649)
                     /locus_tag="NOB43_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983545.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="NOB43_002740"
     CDS             complement(723..1103)
                     /locus_tag="NOB43_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HCI0983546.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1167..2360
                     /locus_tag="NOB43_002741"
     CDS             1167..2360
                     /locus_tag="NOB43_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0983547.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2437..3021)
                     /locus_tag="NOB43_002742"
     CDS             complement(2437..3021)
                     /locus_tag="NOB43_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0983548.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          942 a          578 c          498 g         1004 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt caattgtttc
     2461 aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg cgatttcatc
     2521 tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat ctagccaagg
     2581 agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac cttctagttg
     2641 tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc ttccgtttgt
     2701 gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt cacgactgaa
     2761 ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc cagttggatc
     2821 gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat cataataacc
     2881 ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag ggaataattg
     2941 aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt cactttttaa
     3001 atctagttgt gggaatgcca ta
//
LOCUS       DAIGTA010000130         2908 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.138, whole genome shotgun sequence.
ACCESSION   DAIGTA010000130 DAIGTA010000000
VERSION     DAIGTA010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.138"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..330)
                     /locus_tag="NOB43_002743"
     CDS             complement(<1..330)
                     /locus_tag="NOB43_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepB"
                     /protein_id="HCI0983549.1"
                     /translation="MNKNITKARHFGFLLYPESIPENWREQLESLGVSMAVSPLHDMD
                     EKTNKKDWTSSDVIRNGKHYVKPHYHVLYIARNPVTIESVRKKIKRKLGNNSVAHLEI
                     IDHIKGSY"
     gene            complement(411..560)
                     /locus_tag="NOB43_002744"
     CDS             complement(411..560)
                     /locus_tag="NOB43_002744"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983550.1"
                     /translation="MAESERLVVILPSEIKRKLEEKAKDKSLSMSTYVKLLVTEDLKK
                     SEKGN"
     gene            complement(1047..1226)
                     /locus_tag="NOB43_002745"
     CDS             complement(1047..1226)
                     /locus_tag="NOB43_002745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983551.1"
                     /translation="MEKDIYKQLTRQIQKEKEKGLLDHLDELELKADEINKNRMSAKE
                     KGIKLKDSSLQSDKS"
     gene            complement(1351..1596)
                     /locus_tag="NOB43_002746"
     CDS             complement(1351..1596)
                     /locus_tag="NOB43_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983552.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLKYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1941..2225
                     /locus_tag="NOB43_002747"
     CDS             1941..2225
                     /locus_tag="NOB43_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983553.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            2228..2644
                     /locus_tag="NOB43_002748"
     CDS             2228..2644
                     /locus_tag="NOB43_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983554.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNQPKNHQKGTNKTVTSSNFDPTKFLKR"
BASE COUNT          882 a          583 c          433 g         1010 t
ORIGIN      
        1 atacgagcct ttgatatggt caattatttc taagtgagca accgaattat ttcccaattt
       61 tctcttgatt ttctttctta cgctctcgat tgttacagga ttgcgagcaa tataaaggac
      121 atgataatgt ggctttacat aatgcttacc gtttctgata acatcactac tagtccaatc
      181 ctttttattt gttttttcgt ccatatcgtg taacggacta accgccattg atactcctaa
      241 gctctcaagc tgttctctcc aattctctgg aatagattcg ggatatagta aaaaaccaaa
      301 atgtctagct ttcgttatat tcttattcat gatatactta cctcaattga acactatcag
      361 ttaagcggaa acggtgcgcc aacacatatg tttctgctct ttttttgcgc tcaatttcct
      421 ttctctgatt ttttcaagtc ttctgttact agcaatttaa catatgtcga catactcaaa
      481 cttttgtctt ttgctttttc ctcaagtttt cgcttaattt cactcggtaa aattactacc
      541 agtctttctg attccgccat gcctttcagc ccctttagtt aattgttaat atcatggtaa
      601 acttttgaca actgtattgt caatattttt ttctattttt caaaacggcg gtcaaaacgg
      661 cggtcaaatg gcggtcgaaa aaaaaaggct ctatccattg gtacagtaag gataaagcac
      721 tttttggcac aaaaattggc actcggcaca ctatgggggg gtcgtagtag cccccccaga
      781 ttttccaaat tccaaatttt ttccaaaaat tttccagcgc tatcgctcgg caaatcaaga
      841 ccgtaccttt ttgaaaaaag gcaccccaaa aactttccac tcgccgttaa ggcgtcaaga
      901 acgttcccta tggtcacctt cttgtgtttc cagcttttgg gttttgttta tagccgtcaa
      961 ctccttaaag cctcaaagag acgctaagag ggcttattag cctctctaag cgtctctaat
     1021 tcgatttacc gttgaccgca cgttatctag cttttatcgc tttgcaacga cgaatcttta
     1081 agttttatac ctttttcttt tgctgacatt ctgtttttat tgatttcatc agcttttagt
     1141 tctaattcat ctaaatgatc tagtaagcct ttttcttttt ccttttgaat ttgtcgggtc
     1201 aattgtttat aaatatcttt ttccatcccc catcgcctcc ttaaaagcta ttattattcg
     1261 atttaagacg ttttatttag tttttggtgt tatttcattg gtccaagcta aaaaactctt
     1321 agaagcgatt ttagagccat ttaaacccac ttaattatat tctccatgaa attcgctcca
     1381 tgcgtcaaaa gctgcgtctg aaattccgcc gtcttcgttc actagttgca ttaatttttc
     1441 caacgatcgt tttctttcgg gcgtcatatt tttatatttc aacaattttt cgtctgttaa
     1501 atcgaacttg attgcttgaa ttgcttgctc taatttttct aagttttgaa aatattcgta
     1561 aggaaatttt tccatttttt ctttctccag tctcacaatt tttctagaaa taaaatcact
     1621 tctttgccgt ctatactctc aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc
     1681 gtgcattttt aaatttggtt atcgatcaca cgtgcagcac tcccccccga attttaaaga
     1741 gcataaggaa acgtggtatc actttcttac gaaaggtgct agataggctg tgcctatcac
     1801 gtttctttga aaaaaatttg atatcacttt ttcgccatcg tggatagctt atgtatagta
     1861 ttttggcaaa aaacagctat acaaatatag tatttgtatg gtatacataa attatacata
     1921 attgcaaaag gagatttttt atggacattt tagttcggaa tattgatcca aagtttgttg
     1981 caacaataga caaacgttgc caagaactca cgaataaaac aggagaaaaa tggagtcgaa
     2041 ataaatatct aaaagtttta atcgaaagtg attttgaccg tcaacttacg acttacaaaa
     2101 aagaccaatt cgatttattg ctcgataaat ttattgctat ccaaacagaa aatactcaaa
     2161 tattaagcga gtatgtctac acaaataatc aaatcattga aatgcttatc ggaggaatga
     2221 tataaccatg agaaaaactt ctgtccaaaa acatgttact ttgtacccta gtcatgttga
     2281 cgttttagat tccatcatcg aaaaaaatcc agatatcaat aactactcgg aagccattcg
     2341 ctttttatgt atgagttatg aacccgatac caacacgacc actaccagca atcaggcaaa
     2401 actaaatgct atgggaaaag aaatttccat catgactgaa atcatcgcag aattcgctga
     2461 tttatatcta aaagatacag gcgttcttat cggcacaaat tctaaagtat atcaagaagt
     2521 gaaagaaaaa atcgaagcta aactaaatcc atcaaatcga aatcaaccaa agaatcatca
     2581 aaaaggaaca aacaaaacag tcacttctag caatttcgac ccaactaaat ttctaaaacg
     2641 ataaaaaaca gataggagtt attcctatct gttttttatt tcccaatatt ctattttttc
     2701 attccaagca gttaacggaa gttttcgata tttattcgac gtgtttattc acgccttcaa
     2761 tcatttctcc agtttcagaa tctatccttt ttgcatattg cggccgaaat ccgttctggt
     2821 aattagcatc aaacatcata cggaaaagat tgctgtttga agctatgaca tcaacaacat
     2881 ctctttgatt agtgattcca tactcttg
//
LOCUS       DAIGTA010000131         2882 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.139, whole genome shotgun sequence.
ACCESSION   DAIGTA010000131 DAIGTA010000000
VERSION     DAIGTA010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.139"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(16..1442)
                     /locus_tag="NOB43_002749"
                     /pseudo
     CDS             complement(16..1442)
                     /locus_tag="NOB43_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1685..2140
                     /gene="tnpA"
                     /locus_tag="NOB43_002750"
     CDS             1685..2140
                     /gene="tnpA"
                     /locus_tag="NOB43_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HCI0983555.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYRRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2405..2503
                     /locus_tag="NOB43_002751"
                     /pseudo
     CDS             2405..2503
                     /locus_tag="NOB43_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2726..>2882)
                     /locus_tag="NOB43_002752"
     CDS             complement(2726..>2882)
                     /locus_tag="NOB43_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HCI0983556.1"
                     /translation="DEQEPTESKRHRAQGIIKIAKRMFSIKGVLSYTVLIQKIPNHLV
                     YKNNVED"
BASE COUNT          886 a          517 c          533 g          946 t
ORIGIN      
        1 tctaaaatga tatttttaca caactattac ggttgtttta cgaaattgga cgggactttg
       61 ccagtttaat ttctgtttta tccgttcatt attgtagtaa tagatatagc tatcgatggc
      121 tgattttaat tcctcgaaac agttataaac tttcccgtga aaaatctctt gttttaataa
      181 gccaaaaaaa ttctccataa gtgaattatc taagcagttc cctttccgag acaggctttg
      241 aaagattttg tactccttca atttgtttct ataagctttc atttgatacg cccaaccttg
      301 atctgagtga aacgtacgac gataaggaca atcgttagtg gtctggatag cttactccaa
      361 actttccatt accgctaatg cattgggctt ttcagagata cgataggata aaatctcact
      421 attgaacata tccataaaag gatctagata caatttcttt tgacggataa tgcctttggc
      481 atccacttca tggtatttaa attcagttgt atccgtcgtg attttctgat ggcagatact
      541 ggtgtagaaa cgacgatgga tccgattttt ggctactgct ccgacttgtc ctcgataaga
      601 attgtagcgc cgtgatttac gtgtgtatgt cgttactttt attcctagct tcttgatcag
      661 gcgctgaact ttctttttat tgatagagaa accgcggttt cttagttcat tggtcatccg
      721 taaacagcca taatccttgt gcttctcccg aattttaagc atttccgctt caatctcttg
      781 atctggattt ttacggtcca atcgtttttg ccagtacata aaggttgcct tagggaactt
      841 taaagtttct agaagctcaa ctaatttaaa cggtcctcgg aggcttgcga tgattcgtgc
      901 gattgcttca ttcgtcgttg ttgggcttcc tgttttcgca gcttcctcaa ttcttttaaa
      961 gaggcatttt caatttgaag ggaacggact cgtttctcca actcctcgat gcgttcacgt
     1021 tctttagacg ttgctttagt tgtagatttt ttcttatttt tgggttcata tttcttagac
     1081 aagataggtg gacatccttt cgtttttgag agtccatcga tcccaccctc acggaattga
     1141 tgcatccaac tagcgatcaa attagggttg ttcatgttaa gtgtgttggc aacttcacga
     1201 taggacagct cacttgttag atataactct atcgcatcca gcttaaattg aacagaatat
     1261 tttttctttt gtcgctttct tactagaccc tcttcaccaa attcttgata ggcattgatc
     1321 cagcgcttca cttgtgatgg aaccttaatg gaatacttct ttgccagata atcacttccg
     1381 cctttaccat ccaaataatc atgaacgatc tttaatttaa gttcaaaagt atacttagct
     1441 ataaaaaata ccgacctcca aaagttagat tttttggtct aacttttggg ggtcggtaca
     1501 aaacttaaaa gttttagacc cttttatttt cttaatgact tcagtcagtt ttgtgcgtaa
     1561 agcgtgcgaa acaagaaaac cgcgcgtttc tacgcgtgga agaagtatct ttagcgataa
     1621 aaactccttt cgatatacta gtgagtggct accaaccgct catcagatcg aaaggagttt
     1681 tttcatgtca aatgacgata aaagtttagc atatactcgt tggaattgta agtatcatat
     1741 tatttttaca ccaaaatatc gacgaaaagt aatctatggg caattacgaa aagatcttgg
     1801 aaaaatactt aggaagttgt gcgaaatgaa agatgtggaa atcatagaag cacatgcaat
     1861 gctagatcat attcacatgc ttgttcgagt accaccaaaa atatgtatat ccagttttat
     1921 ggggtatctg aaaggtcgta gtgcggtact aatccacgag cagcacgcaa atctcaaata
     1981 taaatacgga aacaaatcct tttggtcgaa gagatactat gtgagtacag tcggattgaa
     2041 tcaaaagaca aatgaaaaat acatccgtga acaagaagct gatgatcgca ttcgatatat
     2101 tataagtaaa agagagtacg tagaaccatt taaaaaataa agagaagtaa gtgagtgaag
     2161 atgagcagtt ggcggtcttt taaaaatccc cttttaaggg gcagcgagtg tcgacccctt
     2221 ctagggggat taaaaataca cccgtcctca cgggtgtatg ggttactgat agacttgatt
     2281 ttaactggtg tcagaaactt atgtccagaa agggtgatga aattttggca atttacggct
     2341 attcaagaat tagcacaagc aaccaagatt acaaaacaca aattcaaaca ttagaaaatg
     2401 ctggcgcaga aataatcttc ctagaaaatc actggattat cgaacacctt tggaagtatt
     2461 tttgagttac gtaagtattg atgatctgtc taacttaatt tgacaattaa gagtatattt
     2521 acttcagatg gtaaggcaac aaaataaaat acaataggca gatgaactaa taaataaaat
     2581 ctgtattaaa tacagataaa ttaatataaa aatcaaaagg atcataaact tttaacaagt
     2641 gatgaaatgg gtggaaattg attcttatag acagtttgtc tcataacatt gaagtatttt
     2701 gcaattttag cattgaaaca cttttttaat cttcaacgtt gttcttataa acaagatgat
     2761 tgggaatctt ttgaattaac actgtatagc ttagaacacc ctttatagaa aacattcgct
     2821 tagcaatctt aataattcct tgtgcccgat gtcgtttaga ttcagtaggt tcctgctcat
     2881 cg
//
LOCUS       DAIGTA010000132         2865 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.140, whole genome shotgun sequence.
ACCESSION   DAIGTA010000132 DAIGTA010000000
VERSION     DAIGTA010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.140"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            95..1054
                     /locus_tag="NOB43_002753"
     CDS             95..1054
                     /locus_tag="NOB43_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="HCI0983557.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINF
                     LKEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPIS
                     CSVRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEF
                     GHIEGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFK
                     SITFDCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQ
                     VDQAFISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
     gene            complement(1487..2059)
                     /locus_tag="NOB43_002754"
     CDS             complement(1487..2059)
                     /locus_tag="NOB43_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0983558.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2075..2680)
                     /locus_tag="NOB43_002755"
     CDS             complement(2075..2680)
                     /locus_tag="NOB43_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HCI0983559.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          918 a          581 c          471 g          895 t
ORIGIN      
        1 gccgattgta aaattaagct agacaaataa ataagccatt cgtgctacac tcaaaatgta
       61 attccgacta aagaaaacat aggagtgatc acgaatgacc tacacccatc ttaccacgga
      121 tgaactggtg atgatagagt cttactacca ccaaaacatc aaaattgtga aaattgctga
      181 gtacctgaaa cgatctcgaa caccgattta taacgtcatt aatttcttga aagaaggcca
      241 tacggccctc gaatactacc aacagtataa agaaaataag aaacggtgtg gcagacgaaa
      301 catcgtcttg ccaaagaaac aacagtccta cattaaagaa aaaattgccc aaggctggac
      361 gccagacgtt atcattgggc gtaaagagaa accaatcagc tgttccgtaa gaacccttta
      421 tcgccagttc aaggaaaagg tgttcgatga atcgactttg cccatgaagg gtaagcggaa
      481 accaaatgga catcaagaac gccgaggaaa acaggctttt aaacggaata tcgttgaaag
      541 agaaactgat tacccgacat ttaaagaaga gttcggccat atcgaaggcg ataccattgt
      601 aggcattcat cataagagtg ctgtcataac tttggtagaa cgtctatcga aaatcatcat
      661 caccttgaag cccgaggggc gcaaggcgat cgatattgag aatactctga accactggtt
      721 tggatcgatt cccagacatt tatttaaatc cattaccttt gattgtggga aagaattctc
      781 taattggaag gctttaagta accaacatga catcgctatt tatttcgctg atccagggac
      841 tccttcgcaa cgagcactga atgaaaattc caatggcttg ctgcgaaaag atggtctgcc
      901 aaaaaacatg gattttaatc aagtcgacca agcttttatc tcttcagtgg cgaataagag
      961 aaacaatatt ccacgaaagt ccttggatta tcaaacaccc ctggaagtat ttatgagtta
     1021 catgaatgaa gatattttgt ctagcttaat ttgacaaatc aaattattta aaactttgca
     1081 acagaacctt agcagcagtg ctgattttta tgatagttat ttggttctta aatgaaagat
     1141 ctaaagacaa tcaacaccgt agggatatgg agataaaatc aatagagtca atagattatt
     1201 tatcgataat aacactaaaa aagccacgtt cctaaacgtg acttacgctg aacgatatgt
     1261 gttgtttggt agacgaacaa atcgttcatt ataaatatat gatggtatcc taatatagta
     1321 agcgtggcta gcataccttt aattacttta ccttttacag ttaccataca cattttttga
     1381 gcagaaatca agtaaataaa aaaatattat atttcacaac atgctaatag actcatatct
     1441 agaacgcatt aagtatttac ctgtctggtt cgctgagact tcttttttaa ctttcttcaa
     1501 ttttcttctt tattctaaaa agcgtactgc gactgaaacc ggttatagct tcaacttcct
     1561 tatacgattt acctgaagta agcagttcat atgcgtgcct cttcttcggt gtgattgttg
     1621 ctttcggacg tccttctctg aaattaggat tattctttct tgcaaacatt tttccttctt
     1681 gggtacgttc cacaatcata tcacgttcca tttctgctac actcaacaac gtccgtgtca
     1741 ccattcgccc catggacgta ttttcaatcg ttcctagatt caaaaccttg atcgttacgt
     1801 tatcatcgag taaaggttca atgatctcta atgcttctct cgtgttacga gcaaatcgat
     1861 caagcttcgt aacaactatt tcatctccag gcttcagacc agccaacagc tgattgaatt
     1921 ttggccgatc ccgttttgta cccgtaaatt tttctgaaaa aatattcttc ttctctacgc
     1981 cgttctcaag caactgttga atttgttctt ttgtactttg agaagcggtt gagacacgtg
     2041 catatccata tttcgtcatt tggtccacct acttttacaa atcatctatc gtatactcag
     2101 aatacccttc atagaaatag ctgacatcga ttcctttcat atataactcg cgatcgtcaa
     2161 ttttatcagt cagagcattg gaaattagat agcgtatttc caaatcgttt atgggacttc
     2221 gctccattgc agaaagatag tctgctttat cgattaagtt ccaatctaca actttttgca
     2281 attcttcctt taaaatgaga tccagccaaa ttctagtact tcggccattt ccttctcgaa
     2341 atgggtgagc gatattcatc tccacatatt tcttgataat ctcttcaaaa gaagtttgtg
     2401 gcatctgatc aatatgctgt aacgaatgtt ctaaatacat aactggtgca aatcgaaaat
     2461 ttccttttgc aatattgacc gatcggattt ttccggcaaa atcgtaaata tccgaaaata
     2521 gaaattcatg aatttcagat aaacctttaa atgtaccaac ttcgatttca tttatttttc
     2581 cacaatcgta caattctttc gctttttgtt tactgagttt ttcttcaacc ttagccaact
     2641 caacttgatt ggttaatccc aatttattct ctaaaatcat gcgaaatctc cttaacttta
     2701 tgacataagt ttatgaaaca ctctcaaccc cattatatcg cgattttgtt tatgtgtcaa
     2761 aaactattaa gtttctgacc ctctacaaaa ttcacaatag atataatcta ttgaaaattt
     2821 aaaagaagac aaaatagagt acagaaaatg ttttctgtac tctat
//
LOCUS       DAIGTA010000133         2780 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.141, whole genome shotgun sequence.
ACCESSION   DAIGTA010000133 DAIGTA010000000
VERSION     DAIGTA010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.141"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(1014..1304)
                     /locus_tag="NOB43_002756"
     CDS             complement(1014..1304)
                     /locus_tag="NOB43_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983560.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2204)
                     /locus_tag="NOB43_002757"
     CDS             complement(1512..2204)
                     /locus_tag="NOB43_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0983561.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            2599..>2780
                     /locus_tag="NOB43_002758"
     CDS             2599..>2780
                     /locus_tag="NOB43_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0983562.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT          824 a          518 c          397 g         1041 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt
     1681 ttttcttgtg tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct
     1741 gaaagttttg cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt
     1801 tcatcatttt tttggttgat ctcatctagt ttgacattga tttcattttg tttgctttgt
     1861 agttgtgcat ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga
     1921 tttttttggt tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa
     1981 tcttgcaatg tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct
     2041 ttatctgtca atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc
     2101 tctccacccc acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat
     2161 agaaatgcaa cgacaatccc accagtaata aatttctttt tcatttgcat agctccttaa
     2221 tccaatactt ttacatgcta aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa
     2281 ttacatatgt aattttaata taaatactat caaatactca tttaatcctc cttttttatc
     2341 tatttaaaaa atctttttta tagagaaaaa tgcaggttaa tactttctta aataaatatt
     2401 tatggtgaac aaaaacaaaa aagcaagttt tattaaacgt aacccttttc atttcataga
     2461 ttactgtatt tattacaaaa aacgcggatt tgtcataaat tgtcatgctt cttttaccta
     2521 tgaaatattt tcacgtgtta aagtattcct cgttgaacac aacaaataaa actttttaac
     2581 gaataaagga gatttttcat gacatcactt aaaactttac tttttggaac aactttggct
     2641 gccggcgctg cattcttcat gggaacgact gctcatgcgg acgaagctta taccgttcaa
     2701 tcaggtgata ctctatcaac gatttctcaa aaatacgttg gtgataactc cttgatcaat
     2761 gccattgcag aatcaaattc
//
LOCUS       DAIGTA010000134         2778 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.142, whole genome shotgun sequence.
ACCESSION   DAIGTA010000134 DAIGTA010000000
VERSION     DAIGTA010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.142"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            1..329
                     /locus_tag="NOB43_002759"
                     /pseudo
     CDS             1..329
                     /locus_tag="NOB43_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(231..947)
                     /locus_tag="NOB43_002760"
     CDS             complement(231..947)
                     /locus_tag="NOB43_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HCI0983563.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(997..1206)
                     /locus_tag="NOB43_002761"
     CDS             complement(997..1206)
                     /locus_tag="NOB43_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983564.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            1483..2756
                     /locus_tag="NOB43_002762"
                     /pseudo
     CDS             1483..2756
                     /locus_tag="NOB43_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          884 a          627 c          497 g          770 t
ORIGIN      
        1 actcagatgt tgaaagtcaa agaaaagttg actattttag aattaaaacg tacccgtttt
       61 ctatgctatg attgtgggca gaccttttct gcgaaaacgg acttagttga tgaacatcat
      121 caactaacaa aggaactgaa gcaggcgatt ctcatagaac tgtacgaaaa tcaatcacgt
      181 aatctgaaaa tcagaagaag taccgtcggc tcaagcgata ttggaaactc ttactcaaag
      241 attccacgac attggagccg ctcaaacggc attatcatcg actgtttaaa cgaccaatta
      301 gtcaaacaga aatcgtcgat gaaccgttgt gcacaatggt gtcctgaacg tacagcgaca
      361 ccttccatat ccagagcagt cgccacatca cggggatgga tgccatccaa attaaaagca
      421 accacgccag tatgatgttc aggatcttgc ggtccgtaaa tggtgatacc gccgatcgct
      481 tgtaatttag gtaaaacgta ggcaaccagt tcttgctcat aacgatgaat attctccata
      541 ccaatctcat tcaagtaatc gattgctcct gcaatgttcg gagtaccagc ttcaaatttc
      601 catggcagct ctttccatga actatcgtaa agattgacaa aatctatcat ttcaccgccg
      661 aattcgactg gctccatttg ttctaacaat tgacgtttgc catataatac accgattcct
      721 gtcggcccgc acattttatg cccgctaaag gcgaaaaaat ctgcatccaa cgcttgtaca
      781 tcaactgtca tatgcggtgc tgcttgggca ccgactggac tatcctcaac tacaacagcc
      841 tgttcaaccc tcagccgttt caagcacaac aaataacctt ctggatctgg tttgccgacc
      901 tgaagatcat cgatcgtcac aaaggaatca attttttcct taatcatcgg atgtgcttca
      961 aaaaaatagt ctagctcccg cagttcagaa ttgagactac tccgattttc cagtgctgct
     1021 gatccgctgc tcaaaatgtt cagcatccac tggtctccca accgcttgac ttatcccttc
     1081 ataaaaggac agttctgctg ccgtcccaac accttgttga tagtctgcaa aaggaatttt
     1141 atagccgaac tgctccagta aataggcttc agtaaatagt gatgaatact ctcgtaaaac
     1201 atccattcac tgtcaatcat cgtcccatca aaatcaaaaa taagtgcttt ggtcatcttc
     1261 tttccccctt acccaaaaca agcaaaagct gtgtcctgct ctctctacag tatcagcata
     1321 aaaactgccg tctgaaaagt caaaggtgaa agaaatgtgg cgctataatt tctaggactg
     1381 atagtaaatc attctatcag tccttttgag cataaaaaaa caaaacatac agaagctccg
     1441 ttagaattga atcaccacaa cacaatcaaa ggagcgttct gtatgcctga tcttcatctt
     1501 atcaaactat tactaggaat caaagatgga aacattcaaa tcactcatgt cgagaagaaa
     1561 aaaatacatt caatcaacag tatcgttgtt tctgccacgc tcattaaaac gattcagccc
     1621 tgtcctcagt gtaaacaggt gaatcaacat gggctgatcg ttaagaacgg aaagaaaaaa
     1681 tcgctggtcc ttctcaataa gtgtgcgaat caacggactt atcttgcttt ggcaaagcaa
     1741 cggtacctct gtcgtggctg tcacacctat tttacggcga atacctacat tgttgaaaaa
     1801 aactgtttta tcgccaaaca agtacattat aaaatattgg aggaattgac tgaaaaacaa
     1861 gcaatgacga cgatttctaa acattgcggc gtttcttggt caaccgtttc gcgaacactc
     1921 gcttctctgc tccccatgac aaacgtgaaa ataaattggt tgcctcgctg ttcattggta
     1981 gatgaatttc gttcattgaa aaatcaagtc ggtccctatt ctttttcttg tatggatggc
     2041 gatactggga aattactgga tattcttcct tcacgtaaga agaaagatct catttcttat
     2101 tttatgcaat ttgaacgacg tgcacgttta aacgtaaaaa tactcgtaac agatatgaac
     2161 gcctcttatg ctttgctgat aaaagagtgc tttcctcatg ccaaactcgt tgtggatcgc
     2221 tttcacatcg tcaagcacct cattcgcagt tttaaggata tttgactatg agtcatgaaa
     2281 agcttcgacc gaaacgatcc aatacaagcc aaacactatc gacaagtgaa ggctttatct
     2341 cgacttctga tcaaacgaca ggacacgctt gtttatgata aatggacaaa atggcgtaat
     2401 tttggttggg cctatttaac cgaaagtgaa gtcgtagaac gtctactttc tacttctgat
     2461 gaactacgaa tagcttatgc ttactatcaa gaaattcttc aagcttttta tgacaaagaa
     2521 gcggacatct tctttcagct tgtaaaaaca atgcccaagt cggttccaag agaactgcat
     2581 catataaaaa aagcgtttat aaactatgaa tccggcattc gtttagcctt agagttgcct
     2641 tactcaaatg gcaaaataga aaatctgcat acccacatca aagcattgaa acgaatagct
     2701 tacgggttag gatgagaacc agaattttct taatcaatca tctgatcact tattaaacat
     2761 aaaaaaacat ctaaagca
//
LOCUS       DAIGTA010000135         2639 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.143, whole genome shotgun sequence.
ACCESSION   DAIGTA010000135 DAIGTA010000000
VERSION     DAIGTA010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.143"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..470)
                     /locus_tag="NOB43_002763"
     CDS             complement(<1..470)
                     /locus_tag="NOB43_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI0983565.1"
                     /translation="MENENRTDWTLPRKNLNPKTKQPYKRGRNWWIVVYPESLPENWK
                     EIISTEPVAISPLHDKDVNADGTKKKPHYHIVFNYKGNKSFEQMDEMARVLRAPIPER
                     ISGLTGAVRYLTHMDNPEKYQYDNTEIQVFGGFDLESCLALSTGDKRQALKEMLG"
     gene            complement(594..749)
                     /locus_tag="NOB43_002764"
     CDS             complement(594..749)
                     /locus_tag="NOB43_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein repA"
                     /protein_id="HCI0983566.1"
                     /translation="MVEVEKKKVTLSLPVESNDKLEKMAQKYGMTKSGLVTFLINQAD
                     DKGTIFK"
     gene            complement(1293..2504)
                     /locus_tag="NOB43_002765"
     CDS             complement(1293..2504)
                     /locus_tag="NOB43_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003672456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCI0983567.1"
                     /translation="MSFAVARMQKVKSGNLVGVGNHNQRNTDNHSNKDIDVERSHLNY
                     DLVNRTENYKRDIEQFINDNKSSSRAVRKDAVLINEWIITSDNPFFKDKDDKEIKDFF
                     DTAKSYFADKFGDNNIRYAQVHLDETTPHMHLGIVPFNDEHKLSAKTVFNRQALQAVQ
                     DELPKYLNERGFELERGEKGSERKNLTVPEYKKAKDELKEITTTLEQRKSEVLALSND
                     KAPTIKKESLDLKDETKTVKVPSGETIGIGKLRHEFMKNEERKTGNVIIPESKLNAVI
                     KSYEELYKANEKLKNYAETDLPKEITRVKEKYRELAKDYNRLVRKSNQNIETLEELEK
                     ENKSLKNEIKGIYKGFNQFMENTLGATVGQAKKLMNNLMSEVKEFVKGGEFEKIHRNE
                     TKTRDRDELSR"
BASE COUNT          730 a          567 c          366 g          976 t
ORIGIN      
        1 ccaagcattt cttttaacgc ttgtctttta tcaccagtag ataacgctaa acaactttca
       61 aggtcgaatc caccaaacac ttgtatttct gtattatcgt attgatactt ttcaggatta
      121 tccatatgcg ttaaatatct aacagcacca gttaaaccac ttattctttc aggaatcggt
      181 gcccttaaaa ctcttgccat ttcgtccatt tgttcaaatg atttattgcc cttgtaatta
      241 aaaactatat gataatgcgg ctttttcttt gttccgtctg cattaacatc tttatcatgt
      301 aatggactaa ttgccacagg ttcagttgaa ataatctctt tccaattctc tggcaaactt
      361 tcaggataaa caacaatcca ccagttacga cctcgcttat aaggctgttt agtttttgga
      421 tttaaattct ttctaggcaa tgtccaatct gttctatttt cattttccat atttttctac
      481 accttcctag ttactctact aggaaaacaa gggaaaattt gataaacttg agttgcgaaa
      541 tcaaagaaaa ccaaatcttg cgagcccttg ctatcttcct agcagggctt tttttattta
      601 aaaatagtcc ccttatcatc agcttgatta attaaaaatg taaccaaacc tgatttagtc
      661 attccatatt tttgtgccat tttttctagt ttgtcattcg attcaacagg taaagataaa
      721 gtcacttttt tcttctcaac ttcaaccaca aaatgcacct caattctctt caaaatctct
      781 tttacactgt aattatatta tacatacgac aggaatacaa gattttacaa aaaacttttt
      841 ttcacctcga aataggtgct taaaacgttc atataaaggt atttacaaga catttaatct
      901 ttttatctat ttggacaatg gacaatggac acatgggggg tgtcgtagtg cccccatgtt
      961 ttttcgctcc aaaaattccc atgttttttc gccccctgct cccactaaat ttccaaataa
     1021 taaaaccgtg ggctattcgc ccacacccaa caagcgcaaa gcgcttgacc ttgcctctga
     1081 aaagcaactt gataactgca ttcgtttctt tccgtcgtct tagcaaaagc taaacaactc
     1141 aaaaaaagag atcaagggta aatacactca ctacgttcgc ccttgacctc ttttatttcg
     1201 ctgtttttta cgcatttgcc gacgaaaagt aaacaatatg cagaattacc ctagttttga
     1261 taaaaaagcg cttagaacgc aaatatgagc ttctaacgac ttaattcatc cctatctcgt
     1321 gttttagttt cgtttctatg aattttttca aactctccac cttttacaaa ctctttaact
     1381 tcgctcataa ggttattcat cagcttttta gcttgtccaa cagttgcacc aagggtattt
     1441 tccataaact ggttaaaacc tttgtaaatg cccttaattt cgtttttaag cgacttattc
     1501 tctttctcta attcttcaag tgtttcaata ttctgattac tcttacgtac caacctattg
     1561 taatctttcg ctaattcgcg atatttctct ttaactctag tgatttcttt aggtaaatca
     1621 gtttccgcat aattttttag cttttcattt gctttatata gctcttcata gcttttaatc
     1681 actgcattta atttactttc agggataatt acatttcccg tttttcgttc ttcatttttc
     1741 ataaattcat gtcgcagctt accaatccca atggtttcgc cacttggtac tttgaccgtt
     1801 ttcgtttcgt cttttaaatc taaactttct ttcttgattg ttggtgcttt atcgttcgat
     1861 aacgctaaaa cttctgactt tcgctgttcc agcgtggtag ttatctcttt taattcgtcc
     1921 tttgcctttt tatattcagg caccgttaaa tttttacgct ctgacccttt ttcgccacgt
     1981 tcaagctcaa aaccacgctc atttaaatac tttggcaatt cgtcttgtac cgcttgtaag
     2041 gcttgacgat taaaaacagt ctttgctgat agcttgtgtt cgtcattaaa cggcacaatt
     2101 cctaagtgca tatgcggtgt cgtttcgtct aagtgaactt gagcgtagcg gatattatta
     2161 tcgccaaatt tgtccgcaaa atatgatttc gcagtatcaa aaaaatcttt aatttcttta
     2221 tcgtctttat ctttaaaaaa tgggttgtca gaagttatga tccattcgtt tattaataca
     2281 gcatcttttc tgacagcacg actacttgat ttattgtcgt taataaattg ctcaatatct
     2341 cgtttataat tttctgtccg attgaccaaa tcataattta aatgcgaccg ttcaacatca
     2401 atatctttgt tggaatgatt gtctgtattt ctctgattat gattacctac cccgactaaa
     2461 tttcctgatt ttaccttctg cattctcgcc actgcaaatg acatgtaaac actcctaact
     2521 tcggcacaac ttccatgtaa agtataaccc actagactta tttactacgt ttcataagtc
     2581 attaatgcgt gtgctctgcg aggctagttt ttgtgcaagc acaaaaaatg gactgaata
//
LOCUS       DAIGTA010000136         2492 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.144, whole genome shotgun sequence.
ACCESSION   DAIGTA010000136 DAIGTA010000000
VERSION     DAIGTA010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.144"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(367..1659)
                     /locus_tag="NOB43_002766"
     CDS             complement(367..1659)
                     /locus_tag="NOB43_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0983568.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1933..2193)
                     /locus_tag="NOB43_002767"
     CDS             complement(1933..2193)
                     /locus_tag="NOB43_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983569.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          844 a          465 c          382 g          801 t
ORIGIN      
        1 tgtatgggct actctgtgat acttattagc cattaaacta ttttacccac atagcatata
       61 ttttgaaatc gttcattccg taaattcaac taaatatgcc taaaaaaata aaaaatctaa
      121 gatagaataa gatttattca gtcttagatg gatttatagc aactttttcg taacaacttt
      181 aaaaaatacg aaaagaaaga gctgttttac tctgactacg ttgctaaatt gtcgtttaat
      241 cattcattta aaccaaatct ttttttatag aattcgtttt aatcctcctg aatccaaaaa
      301 ctatgaaaac cgtaattaaa tagttaagag tttttaacca ccataattct ctcggctatt
      361 ttgaaatcag ataaattttg atcggacaca tagttgaata aacctaccgt tgttacggaa
      421 ggtaaatcgc atacttttca ttctagagga gaaggtctcg ttgatcatta actgattaag
      481 caccatagcc cagttttgaa ttcgaccacc tgaccacttc gcgtgtaatt ctttcgtgcg
      541 taaataaagt agttttagga gtgcattctc attagagaac gctccttttt ttgtgacttt
      601 tctgaagctg gagtggacac tttcaaccgc attggtagtg tacataattt ttcgaatggc
      661 actaccataa tcaaatagtt gttcaacatg tgcaaagttc cgtttccaga catctacagc
      721 accagaataa tgagaccacc gattttgaaa actgtcaaaa gcagcatgtg cagcgtttag
      781 agaagaagca ccgtagaact ttttcatatc tcggcagact tccttatagt ccttacttgg
      841 aatatagcgc aatgcatttc gaacaagatg aacaatacag cgctgaacaa ttaccgatgg
      901 aaagatcgct tttgcgcctt cttcgaggcc agaaacaccg tccatcgaaa tgaaaaagac
      961 atcttcgaca ccacgtgctt tcagttcatc aaatacttgc atccagcgat ttttagattc
     1021 tgtttgattt aaccataatc ctaaaatctc cttatttcct ttgagatcat agccaagaat
     1081 ggtgtataca gcatattctt tggcttcata attttctcgt aaagtaacat acatacaatc
     1141 aacgaataga aaggcataac actttgctag ggggcgggct tgccattctt ccaattcagg
     1201 aaggacagcg tcagtgatat ctgaaatcat ttcatgggaa atatcaaagc cataaatagc
     1261 ttcgacggtt gcggcaatat ctcgttgact cattcctcgt gcatacatgg aaagaacctt
     1321 cccttcgatg tcggagacat ctcgttttct cttaggaatt aactctggtt caaaggaagc
     1381 ttcccggtct ctaggaacat caatagctac ttcaccaaaa ctggttttaa gcgttttagt
     1441 tccatagcca tttcgacggt tatcgtgttc cttaggctct ttagaatggg catcataacc
     1501 taaatgatta ttcaattctc cttgaagcat tttttcaaaa aggggcccaa acacatcttt
     1561 caaagcatct tgcatgtcat cgacagattc aggttgatag gcattcagaa tggattcagc
     1621 taacttttcg gcatcaggat ttcttttctt tctagccatc gtgtaatcac ctcttgatct
     1681 tattgtagaa aaagaaaaac cgcgaagcaa ccacctgcct aggattaatg gttacttaca
     1741 cggtttatat tacactctca tcattaaaaa agtatctttc gatattacta aacaatgaaa
     1801 ttatctattt gaaatttaaa tctgataata tattgagtgt tccaatgagg gctttgatcc
     1861 tattatccat atctttttca gttttaatat tgatacacat tataagaaaa agaaactttt
     1921 ggttaattta tttcatccca gtgcaaaata taaaaaagta aaatagacca taggcaatag
     1981 attaacaatt aatataatac aagcaaatat tctattcatt gtatttctgc tttcaaaaag
     2041 ttctaatatt gaaagtataa ttccacaaat gcctataata agtatgggaa taagattaga
     2101 aaataacacc ccgagccaat ctgtgaaaat tactatattt actaatatcc ctattaacat
     2161 acctatcata tttattaaat caattttttt cattagatat ttctccttta ttaaatctga
     2221 agtacttata ttaaaataat tctaaactat ttacctcaaa aagtgcaata aattatttct
     2281 gaacaataaa atgatagtca aaacaaaaaa atattgttaa tcgttcagag ccatccgaga
     2341 gtgtaaaata ttttgtgtaa atgaaaaaat ccatacaaaa aaggaaggcg cttctgtaga
     2401 ataaagttaa cgacaaccaa ttcacagaaa agaggacttc cctatgaatg attttactac
     2461 agaaattgtg caaactctag tcactaaagg cg
//
LOCUS       DAIGTA010000137         2401 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.145, whole genome shotgun sequence.
ACCESSION   DAIGTA010000137 DAIGTA010000000
VERSION     DAIGTA010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.145"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            207..2069
                     /locus_tag="NOB43_002768"
     CDS             207..2069
                     /locus_tag="NOB43_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0983570.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..2401
                     /locus_tag="NOB43_002769"
     CDS             2069..2401
                     /locus_tag="NOB43_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0983571.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          867 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
     2401 a
//
LOCUS       DAIGTA010000138         2210 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.147, whole genome shotgun sequence.
ACCESSION   DAIGTA010000138 DAIGTA010000000
VERSION     DAIGTA010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.147"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(45..1364)
                     /locus_tag="NOB43_002770"
     CDS             complement(45..1364)
                     /locus_tag="NOB43_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0983572.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="NOB43_002771"
     CDS             complement(1361..2014)
                     /locus_tag="NOB43_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0983573.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          730 a          336 c          184 g          960 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac
//
LOCUS       DAIGTA010000139         2130 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.148, whole genome shotgun sequence.
ACCESSION   DAIGTA010000139 DAIGTA010000000
VERSION     DAIGTA010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.148"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..74
                     /locus_tag="NOB43_002772"
     CDS             <1..74
                     /locus_tag="NOB43_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983574.1"
                     /translation="NQICEITNVSRASLYRKLSEVNN"
     gene            288..983
                     /gene="vanR"
                     /locus_tag="NOB43_002773"
     CDS             288..983
                     /gene="vanR"
                     /locus_tag="NOB43_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI0983575.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            961..2115
                     /locus_tag="NOB43_002774"
     CDS             961..2115
                     /locus_tag="NOB43_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI0983576.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          715 a          397 c          452 g          566 t
ORIGIN      
        1 taaatcaaat ttgtgaaatt actaatgtat ctagggcttc attatacagg aaattatcag
       61 aagtgaataa ttagccattc tgtattccgc taatgggcaa tatttttaaa gaagaaaagg
      121 aaactataaa atattaacag cctcctagcg atgccgaaaa gccctttgat aaaaaaagaa
      181 tcatcatctt aagaaattct tagtcattta ttatgtaaat gcttataaat tcggccctat
      241 aatctgataa attattaagg gcaaacttat gtgaaagggt gataactatg agcgataaaa
      301 tacttattgt ggatgatgaa catgaaattg ccgatttggt tgaattatac ttaaaaaacg
      361 agaattatac ggttttcaaa tactataccg ccaaagaagc attggaatgt atagacaagt
      421 ctgagattga ccttgccata ttggacatca tgcttcccgg cacaagcggc cttactatct
      481 gtcaaaaaat aagggacaag cacacctatc cgattatcat gctgaccggg aaagatacag
      541 aggtagataa aattacaggg ttaacaatcg gcgcggatga ttatataacg aagccctttc
      601 gcccactgga gttaattgct cgggtaaagg cccagttgcg ccgatacaaa aaattcagtg
      661 gagtaaagga gcagaacgaa aatgttatcg tccactccgg ccttgtcatt aatgttaaca
      721 cccatgagtg ttatctgaac gagaagcagt tatcccttac tcccaccgag ttttcaatac
      781 tgcgaatcct ctgtgaaaac aaggggaatg tggttagctc cgagctgcta tttcatgaga
      841 tatggggcga cgaatatttc agcaagagca acaacaccat caccgtgcat atccggcatt
      901 tgcgcgaaaa aatgaacgac accattgata atccgaaata tataaaaacg gtatgggggg
      961 ttggttataa aattgaaaaa taaaaaaaac gactattcca aactagaacg aaaactttac
     1021 atgtatatcg ttgcaattgt tgtggtagca attgtattcg tgttgtatat tcgttcaatg
     1081 atccgaggga aacttgggga ttggatctta agtattttgg aaaacaaata tgacttaaat
     1141 cacctggacg cgatgaaatt atatcaatat tccatacgga acaatataga tatctttatt
     1201 tatgtggcga ttgtcattag tattcttatt ctatgtcgcg tcatgctttc aaaattcgca
     1261 aaatactttg acgagataaa taccggcatt gatgtactta ttcagaacga agataaacaa
     1321 attgagcttt ctgcggaaat ggatgttatg gaacaaaagc tcaacacatt aaaacggact
     1381 ctggaaaagc gagagcagga tgcaaagctg gccgaacaaa gaaaaaatga cgttgttatg
     1441 tacttggcgc acgatattaa aacgcccctt acatccatta tcggttattt gagcctgctt
     1501 gacgaggctc cagacatgcc ggtagatcaa aaggcaaagt atgtgcatat cacgttggac
     1561 aaagcgtatc gactcgaaca gctaatcgac gagttttttg agattacacg gtataaccta
     1621 caaacgataa cgctaacaaa aacgcacata gacctatact atatgctggt gcagatgacc
     1681 gatgaatttt atcctcagct ttccgcacat ggaaaacagg cggttattca cgcccccgag
     1741 gatctgaccg tgtccggcga ccctgataaa ctcgcgagag tctttaacaa cattttgaaa
     1801 aacgccgctg catacagtga ggataacagc atcattgaca ttaccgcggg cctctccggg
     1861 gatgtggtgt caatcgaatt caagaacact ggaagcatcc caaaagataa gctagctgcc
     1921 atatttgaaa agttctatag gctggacaat gctcgttctt ccgatacggg tggcgcggga
     1981 cttggattgg cgattgcaaa agaaattatt gttcagcatg gagggcagat ttacgcggaa
     2041 agcaatgata actatacgac gtttagggta gagcttccag cgatgccaga cttggttgat
     2101 aaaaggaggt cctaagagat gtatataatt
//
LOCUS       DAIGTA010000140         2110 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.149, whole genome shotgun sequence.
ACCESSION   DAIGTA010000140 DAIGTA010000000
VERSION     DAIGTA010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.149"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(585..692)
                     /locus_tag="NOB43_002775"
                     /pseudo
     CDS             complement(585..692)
                     /locus_tag="NOB43_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            808..2110
                     /locus_tag="NOB43_002776"
                     /pseudo
     CDS             808..2110
                     /locus_tag="NOB43_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332662.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
BASE COUNT          840 a          242 c          323 g          705 t
ORIGIN      
        1 ataatttcat tattaattcg tgatataaaa agttgttaaa tctcttataa tagactatga
       61 tacaaaatca tgcttttaat ctgtgtagat gttgccaaat atttgaaaga catagaactt
      121 gtcagaaaaa ccttaacaat tcctcaatgg gcggataagc taggcaaaag ggctggcata
      181 aacttttcag tccttctaac agaatcaatt gcagataaag cagataacat tcttctttct
      241 ggaagaaata attagaactc aaaagggtca gaaacttaaa agtttttgat cctttatttt
      301 caagtctgat ttgacagatt ttcggcagct catttattta tggtcagaaa tagttgctga
      361 aattttaatc tattagcaaa tagtccagaa cgtatgaaga ggattcggat atcatttgtc
      421 attaacacca taaatattta taaaattcgt gttcacctac aattaaattt aatatataat
      481 attcgttgta agggcttata attttttgtt aatgaacaag atatgtaatt gatagtgtca
      541 atagctattc aaaaatgtag gcttttggcc cataaataac aaggttactt atatgataac
      601 tttttttctt tataatcttt aatccgatag agctttccag tagtttgaat aatcttagcg
      661 tggtgcacta atcgattgat tagtgcattt gtgttcagtc cattgagaca taatagtgga
      721 tagttttact gagaaaattg ataaaaaata gagatataat tcaaatacgt atataatgaa
      781 actaaagata aatacggagg aaaatatatg attataaaaa acttaggaaa tgttaaatca
      841 atagatatac acgttaaaga tttgctgatt tttactggga aaaataatac gggaaaaaca
      901 tataccagct atattttata tggaatttta tcagaactct ttggagcaag atttttcaat
      961 tatttttctc atacagaaat tgaaccacat ttacaaaata gtttaaatat tttattagtt
     1021 agcaaagact ctataaggaa aaaatttaat aatgatgcaa aaaaattttt agaagaaaat
     1081 ttaaaaaaat tgcagttcgt aactttaaag taagtgaaaa taacttcaaa aatctttctt
     1141 ttactatttc agattcagaa attagtgagc tcactggtga tatctttaat tatgagatca
     1201 aaagatacag tataagtggc attgttataa caattcaaaa tgtaggagag aaattaaaaa
     1261 ttagctttga gccaactgat tcatttcagt atcttagcaa agatattgaa attgaagata
     1321 tttataaaat tttagctcaa gagctatcta aaaatgttat tagtttgcca aaggtttttt
     1381 attttccagc cgaaagaact ggtataaatg tctttaagaa cgaactaaat gaaagtcgct
     1441 taaaaacata tgataccttg ctgaatactg tgcaatttac taatttaact aaccaaaaaa
     1501 agaaagctgc cctcaagtac gatctgttaa aaaagaatat tgagctgtta atggagacaa
     1561 cggataatag ttcttatcca aagccaatat cggattatat taattatctg aataacatga
     1621 aaaatagata tgaacagaaa aatgtcaata atatagcatc atatattaga gatgagatta
     1681 ttatgggtaa atatgaaatt gacgaaaaag ataattctgt aagttttaga caaaagtttg
     1741 gtaaaaatag atatagaaaa gaacgaattc cttttcacgt tgtgtcttct tcgattaaat
     1801 ctctatatgg attagattat tacttagaaa attcaagtaa agaaggagac tatcttatta
     1861 ttgatgagcc agaattgagt ttacatccag aaaatcaggt taagttagca aaagtaatta
     1921 cagatatagt tgagagtaaa attaagctaa ttacttctac ccatagtgat ttatttgtac
     1981 gtgagcttac aaatattgtt attgaaaata aattaaatag taagaataat aaaaaaaata
     2041 aattgtctga taaaaatata ggcatatata attttgtagg aaataatgat ataaatgaat
     2101 tagaaaaaat
//
LOCUS       DAIGTA010000141         2056 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.150, whole genome shotgun sequence.
ACCESSION   DAIGTA010000141 DAIGTA010000000
VERSION     DAIGTA010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.150"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            493..714
                     /locus_tag="NOB43_002777"
     CDS             493..714
                     /locus_tag="NOB43_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983577.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="NOB43_002778"
     CDS             715..972
                     /locus_tag="NOB43_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983578.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKAAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="NOB43_002779"
     CDS             complement(1108..1710)
                     /locus_tag="NOB43_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI0983579.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKIRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="NOB43_002780"
     CDS             complement(1777..1932)
                     /locus_tag="NOB43_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0983580.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          464 c          313 g          601 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggcggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaat cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatca ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DAIGTA010000142         1994 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.151, whole genome shotgun sequence.
ACCESSION   DAIGTA010000142 DAIGTA010000000
VERSION     DAIGTA010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.151"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            127..1851
                     /locus_tag="NOB43_002781"
     CDS             127..1851
                     /locus_tag="NOB43_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0983581.1"
                     /translation="MKKKLLTLFLVMSFSIVLSVYYNTIVFSEQINYTEEQYNIEKEK
                     ALKVGYSEEQFKQIMEIPTNLSNENSETRIVNYTMTSNQTKVINKAMEQIGKPYEWGA
                     SGPNSFDCGGLVKYVYKQAVNIELPMGTTNQEQYGTEVSLNSLKPGDLLFYGNRGATY
                     HVGIYKGNGVMIHAPQPGETVKEVNIQYFYPNFAKRILPDEPDYPYIDYNKMVTVTKA
                     WSIWNDLQFSHEIKKAIIGDNYKIGKVYTNPENNNKYGEILVSNKVYGYINFYAVKEL
                     TSVQINRYLTSKDSGQPTWGNLECTISKGQTTKDKIYFVKGAYNLGDGKYLYSIYKDQ
                     DSSEWLGYLKAHVSLAYTPIEEINKNVTVTKNWSIWNNLQWEKEIEKPQIGSVFSARL
                     KLTNVSNNAVYYKLYKSGKFYGYINAEAVKDLTTTKLNKYVTFSVNNEDFWSSLDVNY
                     SKGKTERGRVFYISISYNTADNQPIYSVYTDETCTEWRGYYKGNNFEDTQITMLENKS
                     VKVTKSGYTVWGDLNFWTKSGISNTGDIYTTDRKFYNFTNNAYYYELKKDGRVYGYIN
                     SEAAVEMN"
BASE COUNT          783 a          241 c          348 g          622 t
ORIGIN      
        1 agtttgtaac aaacatatat tttttatatt acaatatttc aacaaattaa aaaaaattat
       61 atcttcttaa acaatgataa tattaaaatg caagcgcttg taaaaaataa ggagaagagg
      121 taaaaaatga agaaaaaact attaacttta tttcttgtga tgtctttctc aatcgttttg
      181 agtgtgtact acaatactat tgttttttca gaacaaataa actacacaga agaacagtat
      241 aatatagaaa aagaaaaagc tttaaaagtt ggttatagtg aagaacagtt taagcagatt
      301 atggaaatac ctacaaattt atcaaatgaa aatagtgaaa caagaatagt aaattatact
      361 atgacttcta atcaaaccaa agtcattaat aaagcaatgg agcaaattgg aaagccatac
      421 gaatggggag catcgggacc aaattctttt gactgtggtg gtttagtgaa atatgtttac
      481 aaacaagctg taaatattga actgcctatg ggaaccacca atcaagagca atacggtaca
      541 gaggtaagtt taaattcact taagcctggt gatttattat tttacggcaa tcgaggtgca
      601 acttatcatg taggtatata taaaggtaac ggtgtaatga ttcatgcacc gcaacctgga
      661 gaaactgtaa aagaggttaa catacaatat ttttatccta actttgcaaa aagaattttg
      721 cctgatgaac ctgactaccc ttatattgac tataataaaa tggtaactgt tacaaaagct
      781 tggtcaatat ggaatgattt acaatttagt catgaaatta agaaagctat tattggagat
      841 aattacaaga tagggaaggt ttatactaat ccagaaaata ataataaata tggagaaata
      901 ttagtaagta ataaagtata tggatacatt aatttttatg ctgttaaaga gttgacctct
      961 gttcaaataa acagatattt aacttctaaa gatagtggtc aaccaacttg gggaaatcta
     1021 gagtgtacta taagtaaagg acaaactaca aaagataaaa tatattttgt taaaggagca
     1081 tataatttag gggatggaaa gtatctatat tctatttata aagatcagga ttcctctgaa
     1141 tggttagggt atttaaaagc acatgttagt ttagcctata ctcctattga agaaattaat
     1201 aaaaacgtaa ctgttactaa aaattggtcg atttggaata atctacaatg ggaaaaggaa
     1261 attgaaaagc ctcagattgg ttctgtattt tcagctagat taaagttaac caatgtatcg
     1321 aataatgctg tctattacaa gctttataaa tctggaaaat tttatggtta tatcaatgct
     1381 gaggctgtca aagaccttac aacaacaaag cttaataagt atgttacatt tagtgttaat
     1441 aatgaagatt tttggtcttc tttagatgta aattattcaa aaggaaaaac tgaaagaggc
     1501 cgagtatttt acattagtat ttcatataat accgcagata accaaccgat ttattcagta
     1561 tatacagatg aaacatgtac ggaatggcga gggtattata agggaaacaa ctttgaagac
     1621 actcaaatta ctatgcttga gaataaaagc gtgaaagtaa caaaaagtgg gtatacagta
     1681 tggggagact tgaatttttg gactaagtca ggaatatcga acacaggaga tatatacacc
     1741 actgaccgaa aattttataa ttttaccaac aatgcttact attatgaatt gaaaaaagat
     1801 gggagggtct atggctatat aaatagtgaa gcagctgtag agatgaacta aaatattgct
     1861 gtcccttaat cttatggggc agcaatattt ttatattatt aatcattttt ctgaagcgag
     1921 ggtagaagaa ttaatcaata gtttttcttg ttttgtaata taatagttta attaccaaaa
     1981 attatttaag taaa
//
LOCUS       DAIGTA010000143         1989 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.152, whole genome shotgun sequence.
ACCESSION   DAIGTA010000143 DAIGTA010000000
VERSION     DAIGTA010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.152"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..211
                     /locus_tag="NOB43_002782"
     CDS             <1..211
                     /locus_tag="NOB43_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCI0983582.1"
                     /translation="NTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEVIPENWR
                     KSLQNDQLLKTISQRFCDTVLSQRI"
     gene            280..546
                     /locus_tag="NOB43_002783"
     CDS             280..546
                     /locus_tag="NOB43_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI0983583.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            536..805
                     /locus_tag="NOB43_002784"
     CDS             536..805
                     /locus_tag="NOB43_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0983584.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(1064..1225)
                     /locus_tag="NOB43_002785"
     CDS             complement(1064..1225)
                     /locus_tag="NOB43_002785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983585.1"
                     /translation="MGSYRFLIRRSWSYASTDSFKSFWPFRVGKNGEVSRLGGGTQPT
                     KVTATGEGT"
     gene            1512..1961
                     /locus_tag="NOB43_002786"
     CDS             1512..1961
                     /locus_tag="NOB43_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCI0983586.1"
                     /translation="MYNEKKIVDIVTLKMVVAEKSLPIEKVRSSFEVGNWLIEEIGDY
                     AQEHPALLCLNTKNEITHFSIVHVGTLNQSVAHPRCIFQRAILANAARIMISHNHPSG
                     NTTPSENDIQFTNRLIKAGEVMGIELLDHIIVGQKKYLSLREEGYWN"
BASE COUNT          649 a          380 c          432 g          528 t
ORIGIN      
        1 aaatacgaat agttatcaag cagccatatt gactgcggtc aatttaggag gggatactga
       61 tactactgct gccgtaactg gtgctcttgc gggtattctt tacgggggtg aagtgatccc
      121 tgaaaattgg agaaaatcgc ttcaaaatga ccagcttctt aaaacgatca gtcagagatt
      181 ttgcgatacc gtgctatctc aaagaatttg aataatggat atgatgcaaa tcttgtttgt
      241 actaacgttg tattgacaaa aaggatttta tttagtacaa tgttagtaca aatgatgaac
      301 ggaggtagaa tcatgtctca atcaaccatt acatttagga ttcccgacga tgaaaaagaa
      361 ctggtattag aatatgcaaa agcacacaat tcttcattga ccgaacttta tcgaaatgct
      421 gtactggata aaatcgaaga tgaaatcgat ctacggactt tacggagtgc aattgaagtt
      481 tccaaagaga aaaaagagag tggtatttct caagaggaaa tggagaaact gctaaatgaa
      541 ttataaagtc atctacatgc cgcaagccca gaagcaatta aaaaaaatgg acagaaacca
      601 agctaaaata attgtcgcct ggatcagaaa gaatttagaa aacacgactg acccgcgtca
      661 gcacggaaaa ggtttgactg gaaataagag tggggaatgg cgctatcgaa ttggaaacta
      721 tcgaatattg gctaatattt gtgattctga aattgaaatc cagatattct caattggaca
      781 tagaagtaca atatataaaa gataaccgtt tttggaacga agtagagttt cgaaagtcaa
      841 tgtataatct tttgaatttt gcataatacc acaggtagaa actacccgat actatcggtt
      901 ggtttctgct tttttatttg gtcttgaaga agaaaacgag tgatctgtgg caaagaaaga
      961 aacaaaaaaa ggacaaaact gttgcttcgc ctgcggtgca gtcgcccctg gctcaaagcg
     1021 caacagtttt tttggctagt ggcaaggtct aactgcttgt tggctacgtg ccttcgccag
     1081 tcgcagttac ctttgttggc tgcgttcctc cgccaagtcg gctgacctca ccatttttgc
     1141 ctacgcgaaa aggccaaaag gatttaaagg aatccgtcga agcatagctc caacttctcc
     1201 ggatcaaaaa gcggtaggaa cccatgccgg gttcccttag ttgaattttt tggttttgcg
     1261 ctacattttt accattgcgg acgccgacta gctgcgaaat agaatgagcc tccaggctac
     1321 gcctactcat tctacttctc gcaagtggct tcgccaggcg gcaagggcaa gcaatgtgct
     1381 acgcaccctt gccgcctgac tgctgcatgg taaaagcttc gcaacaaaac gcaaaaaatt
     1441 cagcctttgg ctaccgctgt gtagcgcaaa gaccaaaagg agaaggtcaa aaaatggaac
     1501 caactacagt tatgtataac gaaaagaaaa ttgttgatat tgtcacactc aaaatggtag
     1561 tagccgaaaa aagtttgcct attgaaaaag tgagaagttc ctttgaggtt ggaaattggt
     1621 tgattgaaga aattggtgac tatgcacaag aacaccctgc gctactttgt ctgaatacga
     1681 aaaacgaaat tacccatttt tcaatcgttc atgtgggaac attgaatcag tcagttgctc
     1741 acccacggtg cattttccaa cgtgctatat tggcaaatgc cgctagaatt atgatttcac
     1801 ataatcaccc ttcaggaaac acaacaccta gtgaaaacga tattcagttt accaatcgat
     1861 taataaaagc cggtgaagtg atgggcattg aactacttga ccatattatt gtcggtcaaa
     1921 agaagtacct ttccttacgt gaggaaggtt attggaacta acgattaaga ctgcctgata
     1981 ataaggcag
//
LOCUS       DAIGTA010000144         1954 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.153, whole genome shotgun sequence.
ACCESSION   DAIGTA010000144 DAIGTA010000000
VERSION     DAIGTA010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.153"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..70)
                     /locus_tag="NOB43_002787"
     CDS             complement(<1..70)
                     /locus_tag="NOB43_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="regulates the transcription of tet(M) by
                     attenuation; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCI0983587.1"
                     /translation="MILKYPENICMLCIPMVMHKNPS"
     gene            complement(315..1247)
                     /locus_tag="NOB43_002788"
     CDS             complement(315..1247)
                     /locus_tag="NOB43_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0983588.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            complement(1244..>1954)
                     /locus_tag="NOB43_002789"
     CDS             complement(1244..>1954)
                     /locus_tag="NOB43_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0983589.1"
                     /translation="PPNSLSTEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGG
                     FLGYVANRGNKYTFELAQSFSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVT
                     QYLVTTEFDDDTVQAIMDEALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPR
                     TAQQQYDVTQHIPLSEAQAGDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYAD
                     LTSPYWQQHLVGAGRIKQ"
BASE COUNT          555 a          401 c          349 g          649 t
ORIGIN      
        1 cactgggatt tttatgcata accataggta tacaaagcat acagatattc tctggatact
       61 ttagaatcac atgataaagg tattcttaaa ctgggtacaa aaaactaagc cctcctaaaa
      121 aaggacatct aattatttgt tcctgctatc aaattgacag tttatttaag aataccttgc
      181 cgcatattta ttaactcctt ttaaatagtc acttaaataa tagcacgtaa gagcatattt
      241 gtaaaggaat ctccaatttt ttatcaaaaa gagtacatga ttacaaagta tctgtaatca
      301 tgtaccaata tttgttattt tacaatcttc caattactcc cgttcttttc aagtaccaaa
      361 tcaaattgag atacctgcgt tgctttggtc tgctggtcga tatactccac tgtcagcgat
      421 accgtgactt gattatcctt acgattgtga ataggattta ccagttcttg aaagatgtac
      481 tcttttccga ttggttttaa tatcccgtca ttcacatagt aggaaagttc actggctgtc
      541 gctgtaggat agagcttgaa gaacgtcgtt aaaaactcat tgatttcatt ggttgtaatg
      601 gaatcaaccg tcccctcact ttcaatggct tttggtttat aacttgattt cttaggtatg
      661 ttggtaatgg tcggattctt aaccagtacc atatttccag aaccatctac atagacactc
      721 actatataag cagagtggac ggtctttgta ttttctccct ctgtaatgag ctggtctaca
      781 ctgtaggtta cattaaactc attgtcgcca gttggctcta ccgtccatat ctgaaatcct
      841 cttacagaag acgatacagg aatatctttg cgtactgtat caacattgag agcttgaagt
      901 tcatctgtca gatagccttt tagactttcc attcgattat caatggactt atcggattgc
      961 tcccatgaat agtagacttt cgcaaagttc tctacaaaat tttctacatg atgagtatca
     1021 acgtattcct tttctatgat agttgtttcg tgaatagtat gagtatctat agctgtaaag
     1081 tgcttgaata tcgcaaagct gaaactaagc cctaaaagta cccacaaggc aatcacaacc
     1141 tttttatgag gattgacctt atagacacga ggtttctttt cctttggtat ctgtttttct
     1201 ttattctgat tttttctaaa tttcatcatt aaatcttcct ttctcattgt ttgattcgtc
     1261 ctgctcccac taaatgctgt tgccagtagg ggcttgttaa gtcggcataa ccgattgggt
     1321 cgcctgcatg aaacatacgg ttattgccaa ggtatatccc aacatgagta atataagagc
     1381 cagcgttata ggtagaatga aagaaaacca aatcgccagc ttgtgcttcc gatagtggga
     1441 tatgctgggt cacatcatat tgctgttgtg cggttcgtgg taagttaatt ccagcttttc
     1501 catacgtcca ttgtgtcagt ccgctacaat caaaagaagt agtcggggaa gctccaccgt
     1561 aaacgtatcg ccagccctca tatttcagtg cttcgtccat gatggcttgt accgtatcat
     1621 catcaaactc tgttgtgaca agatactgcg ttaccagttg cacataaaac atattgccat
     1681 agttgtatcg ccagccccca ttgataggta tggctatggg attggggtaa gacacttttt
     1741 cgccacctga atactctttt gagaaacttt gagccagttc aaaggtatat ttatttccac
     1801 gattagccac ataccctaag aaaccaccac cataattgta ggactggata accgattcta
     1861 aatctacact gagcctttcg ctactggcta ataattcact gaaatacttc acaccttgct
     1921 taatggattc ttctgtactc aatgaattag gtgg
//
LOCUS       DAIGTA010000145         1857 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.154, whole genome shotgun sequence.
ACCESSION   DAIGTA010000145 DAIGTA010000000
VERSION     DAIGTA010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.154"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..614)
                     /locus_tag="NOB43_002790"
     CDS             complement(<1..614)
                     /locus_tag="NOB43_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983590.1"
                     /translation="MTETKFIQDPWSKMTTRNGLRGDEAISALQKSIRRGKEKEACEF
                     AYEMYITSPQFEEKLWRRLLAISVEDVGMGNPMAAIMINNLNAMRKEFQYNESDRAMY
                     FFHAIRYLCQSEKDRSSDLLKNIVIKSFAMGYIPEIPDIALDKHTVRGQAMGRGSEHF
                     LHEASKVIPQAKVDNDYKEQYEKIIETYDPDHVVPSTFSFNPWQV"
     gene            655..1346
                     /locus_tag="NOB43_002791"
                     /pseudo
     CDS             655..1346
                     /locus_tag="NOB43_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
BASE COUNT          570 a          348 c          331 g          608 t
ORIGIN      
        1 acttgccaag gattaaatga aaacgtactt ggcacgacgt gatctggatc ataggtctcg
       61 atgatttttt cgtattgttc cttgtagtca ttatcaactt ttgcttgggg gatcacttta
      121 cttgcttcat gcaaaaagtg ttctgaacca cgccccattg cctgtccccg aacagtatgt
      181 ttatccaacg caatatcagg aatttctgga atatatccca tagcgaaact cttgataaca
      241 atgttcttaa gtaaatccga tgaacgatct ttttcagatt ggcataggta acgaatcgcg
      301 tggaaaaaat acatcgcacg atcggattca ttgtattgga attctttgcg catggcgttt
      361 aagttattga tcatgatggc ggccatagga ttgcccatgc ccacatcctc aacactgatc
      421 gccaatagcc ttctccagag tttctcttca aattgtggtg aggtgatata catttcataa
      481 gcaaattcac atgcttcttt ttcttttcct cgacgaatcg atttctgtaa tgctgagata
      541 gcttcatctc cacgtaagcc gttacgggta gtcatttttg accacggatc ttgaataaat
      601 ttcgtttctg tcataatata atactcctat tagataaaat ttgaggtgaa tcttatggat
      661 gttgaaatgc ttatagataa ataccaactg aatgactcag aagctgaagt cttacgattt
      721 atgaaaaaaa tcgtcagtct ttaaaaaata ttgggattcg tgacgttgcc aaagcatcgt
      781 atgtttctac tgcaacgatt atcaatatgg cgaagaaaat tggatattcc ggttatagtg
      841 agttggtatt tgctctagga aacagccaat ctgacattac gatgccaagc acattctcca
      901 atgaggagaa ggaagcattc atacatttaa tgtctgcgta tcgcgataaa cggattatga
      961 ttcttggctc aggtttttcg caaaatctag ccaattattt ttcggaatct cttaatctat
     1021 atggatttcg tgcgacggcc aatagtcatt tagaatttct tagacagcaa gtgcaacaag
     1081 atattctgct ttttattatt tccaattctg gtgatacagt tcgattagcc gaattagcta
     1141 aaattgcgaa cgatcacttt atcgatgtga tcgcatttgt tgggcaaaaa aattcaaaaa
     1201 tcggtacgct ggcaacatta accattagca cggaaaccta tattccacaa aaaatatctg
     1261 attaccaacc aaatcttttc tttggcacga cactgaatca atttgagctt ttgttgagcg
     1321 cggcgctgaa ggctatttat aaatagaaga acgctgtggc cactgtttct tcaaaatcta
     1381 gtataaagaa tcttctttag aatgtaattg ttttctgtgt gttctgaaca tgtttaggaa
     1441 tttccaaact tgtttagaaa actttctcat tccctccgct gtagaattga actcacataa
     1501 aaaacatcta aaccaaaata tctacaagct tggaaaggat aataggttgt tattaaaaat
     1561 aatttttatt cctgaacctg aataattcat agctttaatt ctttggcaca ttttattgaa
     1621 atatgtatca ctaatatccc tatcaactga ttttgactaa aaagttactt caaacattca
     1681 ctgttcaaaa atattgagga ataaattttg ggtgtaaggc attttgagca tacttctccc
     1741 tggataactt cccagtaaaa aaatcgttag attgttggat tagatccatt gactgcctcg
     1801 cctcaggcga gcaaagaccc tgtagaattc attctgatac acatgataac tagataa
//
LOCUS       DAIGTA010000146         1795 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.155, whole genome shotgun sequence.
ACCESSION   DAIGTA010000146 DAIGTA010000000
VERSION     DAIGTA010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.155"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..447
                     /locus_tag="NOB43_002792"
     CDS             <1..447
                     /locus_tag="NOB43_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCI0983591.1"
                     /translation="NLCVELNNEVSQSTDQTPDERWQTNEKEHLHPYQKNLLNPYFED
                     FIRRKVTKEEMVIFRKCRYSVAPRYIGKEVEIELSDKEDQVQIYYNGELIRSHPLTTK
                     QLNYHEEDYFQILKSDVMSHKEDDGIRAYTRESLKQYDLVEVADEE"
     gene            437..1177
                     /gene="istB"
                     /locus_tag="NOB43_002793"
     CDS             437..1177
                     /gene="istB"
                     /locus_tag="NOB43_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HCI0983592.1"
                     /translation="MKNSHYQELMTNLETLGLNHMREYVPNYIEVANREELSLTEALL
                     ELTRREVDHQNKQKMNRVVARARFSKRTSLEEFDFAFQPSINKREVLDLRHMGFVEKH
                     ENLVFIGSPGVGKTHLTIALGIEACRQGYRTLFITCHELLLRLRTAYEKGTLERVLKR
                     YARYDVLIIDEIGYLPIQKQEADLFFQLLAMRYEHRSTIITTNIVLSRWGELFQSSEI
                     AAAILDRLVHHVKVFKITGKSYRMRDKI"
     gene            1587..1751
                     /locus_tag="NOB43_002794"
                     /pseudo
     CDS             1587..1751
                     /locus_tag="NOB43_002794"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          579 a          369 c          351 g          496 t
ORIGIN      
        1 aacctttgtg ttgagttaaa taacgaggtt tctcaatcaa ctgatcaaac accagatgaa
       61 cgttggcaga cgaacgaaaa agagcacctg catccatacc aaaaaaacct tttgaatccc
      121 tattttgaag actttattcg ccgtaaagtc accaaggaag aaatggtcat tttccgtaaa
      181 tgcaggtact ctgtggcgcc tcgctatatc ggtaaagaag tcgaaatcga actctccgat
      241 aaagaagacc aagtacaaat ctattataac ggagaactga ttcggtcgca tccattaacg
      301 acaaaacagc tgaactacca cgaggaagac tatttccaaa tcttgaaatc cgatgtcatg
      361 agtcacaaag aagacgatgg aatcagagcg tatactcgtg aaagtctcaa gcaatatgat
      421 ctggtggagg ttgccgatga agaatagcca ttaccaagaa ctgatgacca acttagagac
      481 tcttggtttg aatcatatgc gggaatatgt tcctaactac atcgaagtgg ccaatcgaga
      541 ggagctttct ttaacggaag ctcttctcga gctgacacgc agagaagttg atcatcaaaa
      601 taagcaaaaa atgaatcgtg tggtggcacg cgcccgcttt tccaagagaa ccagcctgga
      661 agagtttgat tttgccttcc agccaagtat caataagcgc gaagtgctag acttaaggca
      721 catgggcttt gtggaaaaac atgagaactt ggtttttatc ggcagtcctg gtgtaggcaa
      781 gacacatctg acgattgcat tgggaatcga agcctgtcgt caaggctatc ggacactatt
      841 catcacctgt catgagctgc ttttgcgtct gcgaacagcc tatgaaaaag gtaccctaga
      901 gcgtgttctc aaacgatacg ctcgctatga cgtcttgatt attgatgaga ttggctatct
      961 tccgattcaa aaacaggaag ctgatttatt ctttcagctt cttgccatgc gctatgaaca
     1021 ccgctctacg atcattacga cgaacattgt cttatctcgt tggggggagt tgttccaaag
     1081 ttctgagatc gcagctgcca tccttgaccg tttagtacat cacgtcaagg tgttcaagat
     1141 cacaggcaag tcttatcgta tgagagacaa gatctaaagt gtcgattgtc gacaattact
     1201 attgccgaaa acctacattt ttatcctgcc caaaacctac aattttaagc tgcccttgac
     1261 atcaaaaaga cacttcacaa gctaagtgct atcgacaatt gaaacctttg tataaattac
     1321 ttctataatc agatgacgag ttggattata caacattcaa gaaatggcag aattttcaat
     1381 ggcgctattt aacagaaagt gaagtagttg attgtctacc ctcaatctct tatgaactta
     1441 aaatggctta gcagtattat caaaagctgc ttaacaatta tcacaagaaa cagctagcta
     1501 cttcgagaaa tgaccaaaga agttccctcg aaacttcact atcttaaaaa gcctttttca
     1561 tatctgaaaa aggcttttaa ctagcatttt cgaaaaagta ttttaataca aaattagaga
     1621 atcttcgcac acatatcaaa acattgaaac gatttgctta tggattttgc agttttacca
     1681 atatgcgctt gtggattttt ctaatcaacg ggttaataag ctatgcatta aaagctagta
     1741 aatcttacta actttgttga tcataaatga ccttatcagc ccgatttgac aaaga
//
LOCUS       DAIGTA010000147         1783 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.156, whole genome shotgun sequence.
ACCESSION   DAIGTA010000147 DAIGTA010000000
VERSION     DAIGTA010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.156"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            125..1279
                     /locus_tag="NOB43_002795"
     CDS             125..1279
                     /locus_tag="NOB43_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI0983593.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAIKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1273..1695
                     /locus_tag="NOB43_002796"
     CDS             1273..1695
                     /locus_tag="NOB43_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983594.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
BASE COUNT          690 a          283 c          251 g          559 t
ORIGIN      
        1 cgataaataa cgattatgtt cccaaaacaa tattttatga actataacaa aaatttgtta
       61 tcgcatattg tatattttaa ttatataatt ataggtgtat accacttaaa tttaacacaa
      121 agacgtgatt attttgaaac ccaaaaagaa aatttatcta ggtctcctct tttccttgat
      181 gattggaatt tttagtatag gaattacaaa tacctatgct tcagaaaatt ctaatttcaa
      241 tatcaactcc caaccaattg aagaacaagc aattaatttt gcgaaaactg attttgaaca
      301 ctccataact tcaattcttt taatggaaaa taacaccgaa actgatatta actatactct
      361 tggttcgcca tttaaaatgc tcgatggaga aaatacggca aatagttcta ttttctttcc
      421 agtattttca gacgctgata atacgattaa atatatttat accgtcaaaa aaaatacaaa
      481 tggagaatat tcaggaagta tctcacaatt tttagcaaaa gaacttcaaa atctagtaga
      541 tagtaatata acagatacaa ccttattttt tcaagataat agcatttatt attccgataa
      601 tggacaaatt aaactacttt ggaaatcacc tttaagtaca gaaaaaaatg gtgtttcttc
      661 ctttacagaa aaaaatgatc ttatatccgt aaatataaaa aataaaatta aaaatttctc
      721 taaaaaacaa aattttcctg cgattaaacg tgtaaaaagt gtctcctccg gagataactt
      781 tattatgatt aattggcgta tagcagaaac ccaaacaagt tttccgtggt gtgctgctta
      841 cgtagaagct gctatcttat gtaacaaaac agatgtacat gctacttcag ctagagccat
      901 tatgcattat acctatccta atttaaacaa cagtcaaatt gaatcaaaaa gtcttaatca
      961 agatcaaata ataaaatatg caaattactg tggtgtttat cctaaaaaag tagcacgaat
     1021 actaaacctt tcagaggtcc aaacacaact aagaaaagga aatgccattt atatgggaac
     1081 tgctggttat ggaaattata gtaacagccg tcatgcactt gcattatttg ggtgggtcaa
     1141 tcaaggtggt tatcaaactt actatgtgtg gaatccttgg tataactacc caactgtaat
     1201 aagtgcaaat gcaggaccag ttacaattcc tgtacctgga ggtggtttta cttgggacaa
     1261 taccattaca aattggtaaa taaacccatt gctttagtta tgggtctagt gttagttctt
     1321 ttcttaacta gttgttcaaa aaaacaagaa atacaaaaga ctgatctgat tccttttcta
     1381 ggaacttggc aaactaaaga tcattcagaa cgtctagtaa tcactaattt aaatacttca
     1441 aaaaatatag aacaatatac catcttagta aaagagaaca atcataaaat tcaaatcatt
     1501 gataaaaatt taaatataaa tgaacaagtt ttcatttaca aagcaacaaa taatttacta
     1561 acactgcgct ctaataaaaa acaattagat tacactttta gtttggattc tccaaaaaag
     1621 ctcgtattta ttttgacaac gaatgatggg acagaaggga cagctaaacc aattgaattt
     1681 tttaaagctg attgatgaat agttgtttga tattacaaaa caataatttc accgaaggtg
     1741 aaacaagcga aactttacaa aaagtggcta gcatttgcta gcc
//
LOCUS       DAIGTA010000148         1770 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.157, whole genome shotgun sequence.
ACCESSION   DAIGTA010000148 DAIGTA010000000
VERSION     DAIGTA010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.157"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            52..711
                     /gene="folE"
                     /locus_tag="NOB43_002797"
     CDS             52..711
                     /gene="folE"
                     /locus_tag="NOB43_002797"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HCI0983595.1"
                     /translation="MMMNEDYNEDRYSEENLLESNFPNLNKNSSQFQEKLEDVHEIEN
                     ALKTLMTLCGQDEKNPDLDKTPFRVVKAFLEYTTGYREDPASHLEKTFDITQNDPIIV
                     KDIEFYSMCEHHFAPFFGVAHVAYIPNKKVTGLSKIARVVEGYARRFQVQERLTNQIA
                     DAIESVLEPRGVMVAIEAKHLCVSSRGAKKEEAKTFTLVSRGVYRDNPALRSEFMMAI
                     K"
     gene            725..1669
                     /locus_tag="NOB43_002798"
     CDS             725..1669
                     /locus_tag="NOB43_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0983596.1"
                     /translation="MINKVVFITGGTRGIGRQIALIFAKAGYQLALNYHHNQKIAQEF
                     QQELMTSFSTTVRLYPGDIGREEEVVNMTEKIYQDFGQLDILILNAGPFIHEEIKLKD
                     CTTDQWLHMMNTNLNSFFYLMKAILPHMERQNWGRIVTLGYDQIERVTGWPQRGAYSA
                     AKTGVAAAVRTLAVEEKEFNITVNMVCPGDIKAQWKEASIEEAEKEQLSEQAKKEKFI
                     EGTRKEKFLEEVKKEKAPEEAEQEKSVEKTEKLNKVKRTDTISSAFENANSKRKATGE
                     DVAQTIYFLCQDSAEYLTGNILNLAGGENIIARKMTEK"
BASE COUNT          653 a          271 c          367 g          479 t
ORIGIN      
        1 cacaaactat tttacgctct caaatcatca gtaactaagg agacatgaca aatgatgatg
       61 aatgaagatt ataatgaaga ccgctatagc gaagaaaatt tattagaaag taattttccc
      121 aacttaaata aaaattcttc ccaatttcaa gaaaaactag aagatgttca tgaaatagag
      181 aacgccttaa aaaccttaat gaccttgtgt ggacaagacg aaaaaaatcc tgatttagat
      241 aaaacaccgt ttagagtagt caaagctttt ctagaatata cgacaggtta cagggaagac
      301 ccagcttctc atttagaaaa aacctttgat attacccaaa atgatccgat tattgtgaaa
      361 gatatagaat tttattccat gtgtgaacac cattttgctc ctttttttgg agtggctcat
      421 gtggcttaca ttcctaataa aaaagtaaca ggattatcta aaattgctcg agtagtagaa
      481 ggttacgcca gacgttttca agtgcaagaa agattgacca atcaaattgc cgatgctatt
      541 gagtcagttt tagaaccacg tggtgtaatg gtggcgattg aagcgaaaca tttatgcgtt
      601 tcaagtcgcg gggcaaaaaa agaagaagcg aaaactttta ccctagtaag ccggggtgtc
      661 tatcgggaca atcctgcgtt acgttcagag tttatgatgg ccattaagtg aggaggtagg
      721 aaagttgatt aataaagttg tctttattac aggaggaaca agaggaattg ggagacaaat
      781 agcccttatt tttgcgaaag ctgggtatca acttgcctta aattatcacc ataatcaaaa
      841 aatagcccaa gaatttcagc aagaattaat gacttctttt tccaccactg tccgccttta
      901 tccaggagat attggaaggg aagaggaagt agtgaacatg actgaaaaaa tttatcaaga
      961 ttttggtcag ttagatattc taattttaaa tgctggtcca tttattcatg aagaaattaa
     1021 attaaaagac tgtaccacgg atcaatggct gcacatgatg aatactaatt taaatagttt
     1081 cttctattta atgaaggcaa ttcttccaca tatggaaagg caaaactggg gacggattgt
     1141 tacgttaggg tacgatcaaa ttgaacgagt gactggttgg cctcaaagag gagcatacag
     1201 tgcagcaaaa acaggggtgg cagctgccgt tagaactcta gcagtggaag aaaaagaatt
     1261 taatattaca gtaaatatgg tttgccccgg agatattaaa gcccagtgga aagaagcaag
     1321 cattgaagaa gctgaaaagg aacaattaag tgaacaggca aaaaaagaaa aattcattga
     1381 aggtactaga aaagaaaaat ttcttgaaga agtcaaaaag gaaaaggccc ctgaagaagc
     1441 tgaacaggaa aaatccgttg aaaaaactga aaaactcaac aaagtaaaaa gaaccgacac
     1501 tatctcaagt gcttttgaaa atgccaactc taaaagaaaa gccacgggtg aagatgtggc
     1561 gcagacgatt tactttctct gtcaagatag tgctgaatat ttaacaggga atattttaaa
     1621 tctagctgga ggagaaaata ttattgctcg aaaaatgact gaaaaatagc cttatttttg
     1681 atggaatttt tcctctttag aagacacttg agttttggta taatcaaggt aacatggtgt
     1741 ttaacttttg agagcgtaaa atagtttgtg
//
LOCUS       DAIGTA010000149         1656 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.160, whole genome shotgun sequence.
ACCESSION   DAIGTA010000149 DAIGTA010000000
VERSION     DAIGTA010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.160"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..463
                     /locus_tag="NOB43_002799"
     CDS             <1..463
                     /locus_tag="NOB43_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCI0983597.1"
                     /translation="NESDYNKRDQVLLVKLNEEISVEEAVRTFNASDMVNYAEPNYVV
                     ELEPLNDVEEPNTTDSLGNRSIILNDPNWSKQANLREISMPSAWEETKGSKDVKVAVI
                     DSGIDYQHEDLSGNVDESLRYDFFDDDTDPMDTMGHGHILPGLLVLKQTTN"
     gene            493..1620
                     /locus_tag="NOB43_002800"
     CDS             493..1620
                     /locus_tag="NOB43_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HCI0983598.1"
                     /translation="MVPIRVFGSSGGTSLAILTEAINYASQKGFPIINFSIGSVVYSS
                     TEEAIKNYPGLFVAAAGNNGIDMTDKPFYPASLDIPNIITVGNSSGYERSSDSNYSKT
                     GVDLFARGFRVFSTFLGSKYTYMSGTSMATPHVTGSAALALSLDPDLSTDELKKIILN
                     SVDSFYELSDLCLTGGRLNTNNVVRQVTGKLTASNITLRLNSEWSDEIAKEMCHVHWI
                     DQSGNDLTDQVVVLKNEVDTSNFGDYEVVFASPDLTDQISVTVTVPRLRKLTLGKETA
                     TIDIGSAWDSVIAIDTFQVKAIDDFGNDVTNQVQVTINADIDTINSIQAVIKFEVPEL
                     GLAQIGRLNITAKNSTINGLNEVSIEHVKKIMSFSKKNLDI"
BASE COUNT          561 a          234 c          356 g          505 t
ORIGIN      
        1 aaatgaaagc gattataata agcgagatca agtattatta gtgaaattga acgaagaaat
       61 tagtgtggaa gaggcagtaa gaacatttaa tgcttctgat atggtcaatt atgcagagcc
      121 aaactatgtg gttgaactag agccgttgaa tgatgttgag gagccaaata caactgattc
      181 tttaggaaat cgatcaatta ttcttaacga tcctaattgg agtaaacaag ctaatttaag
      241 agagattagc atgccatccg cttgggaaga aaccaagggt tctaaggatg tgaaggtagc
      301 ggtcattgat tcaggaattg attatcaaca tgaagatctt tctggaaatg tagatgaaag
      361 tttgagatac gatttttttg acgatgatac agatcctatg gatactatgg gacatggaca
      421 catattgccg ggattattgg tgctcaaaca aacaacgaat taggtgttgc tggaataaat
      481 tgggatgtta cgatggtacc tatacgtgta tttggtagta gtggaggtac cagtttggca
      541 atcttaactg aagctattaa ttatgcatcc caaaaagggt ttccaattat caattttagt
      601 ataggtagtg ttgtttatag cagtacagaa gaagcaatta aaaactatcc tggattattc
      661 gtagcagcag ctggaaataa tgggatagat atgactgata aaccttttta cccagcttct
      721 ttggatatac ctaatattat tactgtagga aattctagtg gttatgaacg aagttctgat
      781 tcaaattata gtaaaacagg tgttgattta ttcgctagag ggtttcgtgt ttttagtaca
      841 tttctaggaa gtaaatacac gtatatgtca ggtacctcga tggcaacacc tcatgtcact
      901 ggtagtgctg cattagcgtt gtcactagat cctgatctat ctactgatga attaaaaaaa
      961 atcattttaa atagtgttga ttcattttat gaactatctg atttatgtct tacaggggga
     1021 agactaaata cgaataatgt cgtacgacaa gtaacgggta aacttactgc atctaatatc
     1081 acattaagat taaatagtga atggtcagat gaaattgcta aagagatgtg tcacgttcac
     1141 tggattgacc agtcaggaaa tgatttgacg gatcaagtgg ttgttctaaa aaacgaagtg
     1201 gatacatcta actttggcga ttacgaagta gtatttgcat cacctgattt aacagatcaa
     1261 atctcagtta cagtgaccgt acctcgatta cgtaaactta cgctaggaaa agaaacagca
     1321 accattgata ttggttccgc atgggatagt gtcatagcca ttgatacttt tcaagtgaaa
     1381 gctatagatg attttgggaa tgatgttaca aatcaagtac aggttactat taatgctgat
     1441 atagatacaa ttaattcaat tcaagcagtg attaagtttg aagttccaga attaggctta
     1501 gcccaaattg gtagactgaa tattactgca aaaaatagta caatcaatgg attgaatgaa
     1561 gttagcatcg agcacgtaaa aaagattatg tcgttttcga agaagaattt ggacatttag
     1621 agggtgatac gattgtcggc atccaccata aaagtg
//
LOCUS       DAIGTA010000150         1608 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.161, whole genome shotgun sequence.
ACCESSION   DAIGTA010000150 DAIGTA010000000
VERSION     DAIGTA010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.161"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            3..788
                     /locus_tag="NOB43_002801"
     CDS             3..788
                     /locus_tag="NOB43_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HCI0983599.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            812..1608
                     /locus_tag="NOB43_002802"
                     /pseudo
     CDS             812..1608
                     /locus_tag="NOB43_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757334.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
BASE COUNT          431 a          342 c          375 g          460 t
ORIGIN      
        1 ctatgcagta ttatgatcag catctccaca cgtatttttc ctttgattca gaggaaaaat
       61 ttgaaaacta tttagcctat cagccggagt ttttcgtttc tacggatcac tttgatttaa
      121 acaatccatc taccggaaaa gatgacattc cggattatcc agcctatata aacaaactgg
      181 actctttaaa agaaacctat tccaccaaat ttctgcgagg tatcgagatt ggcgttgttc
      241 caggacaaga agagcggatc gtggattacc tcgctcagca tccttatgat ttaaagctgg
      301 taagtattca tcaaaatggc cgctttgatt atatggacga tgtggtttta accaaagatc
      361 ccattcaaac taccaaggaa tattttgatc agatgttgca ggtcttgacg gattttccag
      421 aaggagatat tttgactcac tttgattatg gattacgccg cttcaccttc acagcggaag
      481 aattcgcgga gcattttgag gctcagctgc taacgatttt caaaaaggtt gttgaacgag
      541 aattggcgat ggagttaaat gccaagagct tcttgaaata cggcaacgaa gacctttacc
      601 gttatgccgt tcctttgtat caaagtgtcg gcggaaagct ctttacctta ggctcggatg
      661 ctcatgttgc cgaagattat cagctgggct ttaaaaaaat gagtcagctg ttggcagact
      721 gtcaggtaga aaagttgcta gtcattcaag gaaaagaacg ccgcctgacg ccgctgccga
      781 ttttgtgatt cctatataat agaagaaagt ggtgaaaaaa atgagcaacc tgtgggacta
      841 caatcaagag gcacccatcc attatttaat tgcgcgacat tgggatgcgt tgaaaattga
      901 ggcggtttgc cgatccttgt tagcagccgt tccaaaacaa caactggaaa attttttggt
      961 ggctgacagc ttgcagcggg aaaaagttca ggcttatttt gcagccttta aagatcagcc
     1021 tttggaatat ttgcatgcgc agtttcatct tttttatcaa gtagccgccc cagatgacta
     1081 caacgattta cgaggacagc tgcaattgac ctttcaagcg gatgaaaccg cctataccgt
     1141 tttattggga atggctcgcc ttggtgatca ggcgaaggtc gagtggcgga ttttcgatat
     1201 ttgatggcag gatcaaggcg tttcagttgc aaaccttcct ctctttcaat tagaaaaacc
     1261 gcagcaggaa gaagtttgtg tgctggtcac cgatgctggt gaaattcgtc tccgcttatt
     1321 tcctgaccaa gctcccctgg ctgtagccaa ctggcgctcc ctagctgagc aaggcgttta
     1381 tgacaacaca cctttcggct cgtgtcatta aggaatttgt tattcaaggt ggcgctttgg
     1441 atggttctgg tgatgaagct gtttccagct atgagggctt tttcgctgat gaagtgcatc
     1501 gcggacttta tcattttaat ggcgccttgg ccttagggga ccacggcccc cacaccaacg
     1561 gcaaccagtt ttttattgtg caaaacacaa aggcgcaggc tgacctgc
//
LOCUS       DAIGTA010000151         1542 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.162, whole genome shotgun sequence.
ACCESSION   DAIGTA010000151 DAIGTA010000000
VERSION     DAIGTA010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.162"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            31..849
                     /locus_tag="NOB43_002803"
     CDS             31..849
                     /locus_tag="NOB43_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0983600.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYAMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(922..1281)
                     /locus_tag="NOB43_002804"
     CDS             complement(922..1281)
                     /locus_tag="NOB43_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0983601.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
BASE COUNT          499 a          250 c          284 g          509 t
ORIGIN      
        1 gaagatatca aaggcgacag gagtgttttt atgaataaga atcctcataa tctaaagttg
       61 gtagcagtag atatggatgg aacatttgct cgtactgatt acacatacga tatcccaagg
      121 ttcaaggctg ttttatcgcg aatgaaagct gttgattgtc aatttgttgt tgcaagtgga
      181 aatcaatact accaattgag atcgttattt ccaaattatt atgatgaatt aagttttgtt
      241 gctgaaaatg gtgcttttgt taaagataaa acagaggtac tattttcagc cgatatgcct
      301 agaaaagcga tcgaggtggt ccttgattta tgtaaagact atcctgaagt aaaaaatgtg
      361 atgtgtggtc tgaatagtgc ctactgtgaa agaggaaagg tgagtcaagc attttttgat
      421 ctaaccaata tctattacca tagattagaa tgggtagctg attttgcaga agttcaagat
      481 aaaattttaa aatttgctcc gactatgcct gttgaaaaaa ccgaatttta cgttgaattg
      541 ttccgtgaaa aattagccgg gctattagta cctaccagta gtggtcatgg ttctgtagac
      601 ttgattcttt ctgagtgcca taaaactttc ggcttgaaaa tgttagttga gcgcttgggg
      661 attaatcctg accagtgcgt tgcttttgga gatgggggca atgacattga gatgttggag
      721 tattgtggtc tgagttatgc aatggataat gcaacggaag ctgttaagca agttgctaag
      781 catcaatgtc cttcaaatga cgaagacggt gttttagtga cgctcgatcg attgttccct
      841 aacacgtaaa cactaggtaa ttcatcaaaa aacctcgata taagaaatat tcgaggtttt
      901 aaaactatat ttagaacaga tttacgaagc gtctgatgag tcaaaataga cttggacatt
      961 gctatctaaa ataccacttt cattctttaa acgaattgtt tgatttgatg gagttacctc
     1021 taatactaaa tgcccattaa taaaggtagt atcgtattca gatgttttaa ctgttgcttc
     1081 ttcgcaaggt attgttaaat catatgctgg aatataatgt tgtgtggaaa ctaataaaaa
     1141 atgatcacca atcatacagc atccctctgc tgaagaaaat tgattagagc catcatttaa
     1201 agttaacaag aatccatcct ttaaacgagg tacttgctta aatacttctg gttgtacttc
     1261 taaaaataaa ttatcgctca ttttcacgac caccattgac ttccacagtt gaaattgaca
     1321 ttttatttaa cacacctatt cccccttaac tataactcaa ttctatataa aaaatattct
     1381 attctcaaat aattgaactt ttcaaatcgc caatttactt cggctttatc agagctcatt
     1441 catatcaaga gcgattaacg ctgtaaaaat taaaccgaag atctgataaa ttttctctat
     1501 tttctacaat atttaaaacg cttccttagt ctattatata tc
//
LOCUS       DAIGTA010000152         1472 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.163, whole genome shotgun sequence.
ACCESSION   DAIGTA010000152 DAIGTA010000000
VERSION     DAIGTA010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1472
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.163"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(74..158)
                     /locus_tag="NOB43_002805"
     tRNA            complement(74..158)
                     /locus_tag="NOB43_002805"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(122..124),aa:Leu,seq:caa)
     gene            complement(176..247)
                     /locus_tag="NOB43_002806"
     tRNA            complement(176..247)
                     /locus_tag="NOB43_002806"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(213..215),aa:Gln,seq:ttg)
     gene            complement(257..329)
                     /locus_tag="NOB43_002807"
     tRNA            complement(257..329)
                     /locus_tag="NOB43_002807"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(294..296),aa:His,seq:gtg)
     gene            complement(391..475)
                     /locus_tag="NOB43_002808"
     tRNA            complement(391..475)
                     /locus_tag="NOB43_002808"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(439..441),aa:Leu,seq:caa)
     gene            complement(496..566)
                     /locus_tag="NOB43_002809"
     tRNA            complement(496..566)
                     /locus_tag="NOB43_002809"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(532..534),aa:Cys,seq:gca)
     gene            complement(612..683)
                     /locus_tag="NOB43_002810"
     tRNA            complement(612..683)
                     /locus_tag="NOB43_002810"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(649..651),aa:Gln,seq:ttg)
     gene            complement(695..767)
                     /locus_tag="NOB43_002811"
     tRNA            complement(695..767)
                     /locus_tag="NOB43_002811"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(732..734),aa:His,seq:gtg)
     gene            complement(770..843)
                     /locus_tag="NOB43_002812"
     tRNA            complement(770..843)
                     /locus_tag="NOB43_002812"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(809..811),aa:Trp,seq:cca)
     gene            complement(850..930)
                     /locus_tag="NOB43_002813"
     tRNA            complement(850..930)
                     /locus_tag="NOB43_002813"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(894..896),aa:Tyr,seq:gta)
     gene            complement(932..1007)
                     /locus_tag="NOB43_002814"
     tRNA            complement(932..1007)
                     /locus_tag="NOB43_002814"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(972..974),aa:Phe,seq:gaa)
     gene            complement(1043..1115)
                     /locus_tag="NOB43_002815"
     tRNA            complement(1043..1115)
                     /locus_tag="NOB43_002815"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1080..1082),aa:Asp,seq:gtc)
     gene            complement(1125..1197)
                     /locus_tag="NOB43_002816"
     tRNA            complement(1125..1197)
                     /locus_tag="NOB43_002816"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1162..1164),aa:Val,seq:tac)
     gene            complement(1213..1284)
                     /locus_tag="NOB43_002817"
     tRNA            complement(1213..1284)
                     /locus_tag="NOB43_002817"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1249..1251),aa:Glu,seq:ttc)
     gene            complement(1299..1388)
                     /locus_tag="NOB43_002818"
     tRNA            complement(1299..1388)
                     /locus_tag="NOB43_002818"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1352..1354),aa:Ser,seq:gga)
BASE COUNT          428 a          380 c          333 g          331 t
ORIGIN      
        1 atttggaggt aattacataa aaacaaaaaa aatatagcaa ctctctataa gaaagttgct
       61 atattgataa ttataccggc ggccggggtc gaaccggcac gtcctcaacg gacactggat
      121 tttgagtcca gcgcgtctgc caattccgcc acgccggcaa atttaaaaat aataactggg
      181 gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc cttgccttac cgcttggcta
      241 taccccaaga ataaagggcg aatgatggga atcgaaccca cgaatgccgg agccacaatc
      301 cggtgcgtta accacttcgc cacattcgcc atcataaaag atgttattta atttctcaat
      361 aaaaaactaa gatgaagaca tcttagtcaa taccggcggc cggggtcgaa ccggcacgcc
      421 ctcaacgggc actggatttt gagtccagcg cgtctgccaa ttccgccacg ccggcaagtt
      481 gatttattag tactaaggcg gtaaccggat ttgaaccggt gatgaaggtt ttgcagacct
      541 ctgccttacc acttggctat accgccatta tactattatc aatctataaa ataaagaata
      601 aattatagaa actggggtag ctggattcga accaacgcat gagggagtca aagtcccttg
      661 ccttaccgct tggctatacc ccaagaataa aaagggcgaa tgatgggaat cgaacccacg
      721 aatgccggag ccacaatccg gtgcgttaac cacttcgcca cattcgccat ggcaggggca
      781 gcaggaattg aacccacact aacggttttg gagaccgctg ttctaccttt aaactatgcc
      841 cctataaaat ggaggagagt ggattcgaac cactgaaccc taaggaacgg atttacagtc
      901 cgtcgcgttt agccacttcg ctactcctcc atggtggcgc gggacagaat cgaactgccg
      961 acacacggag cttcaatccg ttgctctacc aactgagcta ccgcgccata ttttaaaatt
     1021 attaattgaa taacaagaac gacggttccg acgggaatcg aacccgcgat ctcctgcgtg
     1081 acaggcaggc atgttaaccc ctacaccacg gaaccagttc attatggagg ttaacgggat
     1141 cgaaccgctg accctctgct tgtaaggcag atgctctccc agctgagcta aacctccaac
     1201 attcaattaa aatgacccgt acgggattcg aacccgtgtt accgccgtga aagggcggtg
     1261 tcttaaccgc ttgaccaacg ggccaggtaa atttgctacg gagagtaagg gattcgaacc
     1321 cttgagacag tttggcacca tctacatgat ttccaatcat gctccttcgg cctctcggac
     1381 aactctccag agtgaaagaa gctcaatact ctttctcaaa atgagaactc cggcagtagg
     1441 actcgaacct acgacatcat gattaacagt ca
//
LOCUS       DAIGTA010000153         1409 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.164, whole genome shotgun sequence.
ACCESSION   DAIGTA010000153 DAIGTA010000000
VERSION     DAIGTA010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.164"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..1359
                     /locus_tag="NOB43_002819"
     CDS             <1..1359
                     /locus_tag="NOB43_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HCI0983602.1"
                     /translation="LFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKE
                     HLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSS
                     FKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNW
                     HIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPI
                     VYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPK
                     GKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDP
                     VAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEG
                     ARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFS
                     RN"
BASE COUNT          466 a          255 c          299 g          389 t
ORIGIN      
        1 ctttttagtg atgaagaaat ttctgtaagt gttccagaag cagctgccac cattattcca
       61 gtaaaaggac atcaacgagt tgtaggaacg aaagcagaca aaatcaaaca cttacctata
      121 acagagaaag aacatctcct tcctttggaa gaacaatttt gtgaacattg cggttcacag
      181 atgaaagata tcggacggac aaaagtacga gaagaaattc gtttccatca ggctatgttg
      241 gattgtctca cccattatca acatacctat tgttgtaaaa gctgcgaaaa agaaggactt
      301 tcttctttta aaaaagcgat cgttcctaaa cctttgattt ctaatagctt aggttccaat
      361 agtttagtgg cggaaacgat ccggatgaaa tttggtcaga aagttcctgc ctatcggcaa
      421 gagaactatt ggaaacaaac acatgggttg gatatttcga gagataatat caccaattgg
      481 catattaaag cagtgcaaaa cgcgttagac cctttaggag aacgattaag agtctatctt
      541 aatcaagaag agattctaca cggggatgaa acaagttatc gtgtgattga aagtgccaaa
      601 acagatacct attactggca gttttgtaca ggaaaagaca gtcagcatcc catcgtttat
      661 tatcaccacg acgaaagtcg tgctggagat gttccgaaaa cttttctcaa ggagtttaca
      721 gggtatttac actgtgacgg ctatagcggg tataatgccg tggaaagtgt acgacttgtc
      781 tattgtttcg cgcatgttcg gcggaaattt ttcgaagcaa ttccaaaagg aaagaaaaac
      841 acggatattc ccgcagctca agcagtcaaa caattggata aatggtttgt cctagaaaag
      901 aaatggaaag acttttctcc tgagaagcga ttaagctgtc ggcaacaaga actgcgtcca
      961 ttatttattg ctttttatga gtggatggca acgatagatc ctgttgcaaa atccaagttg
     1021 gatgcagccg ttcaatatgc gtgtaaacta cgaagtggtt ttgaacctat ttttgaagat
     1081 ggtcgtttag aactcacaaa taatcgtgcg gagcgaaata tcaaagagct ggtgatagga
     1141 cggaaaaatt ggttgcattc cacaagtctt gaaggagcac gaacttcagg aatcattctg
     1201 agtgtatata aaacagcaga acttaacgga ttgaatcctg taaagtatct agagtttcta
     1261 tttgataaga taccaaatct tcccgtactt tcagcagaaa ctttagatca actgttgcct
     1321 tggaacaagg atgtacaaca acatttttct cgtaactaaa aacgccaaac attcccgatt
     1381 ctattctata ggtcgggtta tttgacgta
//
LOCUS       DAIGTA010000154         1389 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.165, whole genome shotgun sequence.
ACCESSION   DAIGTA010000154 DAIGTA010000000
VERSION     DAIGTA010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.165"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            278..820
                     /locus_tag="NOB43_002820"
     CDS             278..820
                     /locus_tag="NOB43_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983603.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            976..1326
                     /locus_tag="NOB43_002821"
                     /pseudo
     CDS             976..1326
                     /locus_tag="NOB43_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414636.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
BASE COUNT          551 a          164 c          265 g          409 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 tgaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccagatggaa tggcaacact ttttttgaca aaaattataa ggtgttgtga atgctgcggt
     1381 gttatggct
//
LOCUS       DAIGTA010000155         1365 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.166, whole genome shotgun sequence.
ACCESSION   DAIGTA010000155 DAIGTA010000000
VERSION     DAIGTA010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.166"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(24..635)
                     /locus_tag="NOB43_002822"
     CDS             complement(24..635)
                     /locus_tag="NOB43_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HCI0983604.1"
                     /translation="MLQNILSALAVYISTSIDYLFILLIIFSQNHTKKGLRQIFFGQY
                     LGTGILVAISLFAAYVLNFIPQDWIIGLLGLIPIYLGIRVAFVGEEEEEEGEVVEKLG
                     SRGTNRLFWTVSLITIASGGDNLGIYIPFFTSLSFSEIVTSLIVFAISVAVLCYISYK
                     FAKISFVSETLEKYERIIVPIVFIGLGIFIMIENGTIQTILGL"
     gene            complement(652..1017)
                     /locus_tag="NOB43_002823"
     CDS             complement(652..1017)
                     /locus_tag="NOB43_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983605.1"
                     /translation="MTAEVCTTTCIHKEKVASVKNNLKDKDLSTLLVLGKCFSDSSRI
                     KIFYALETYKEMCVCDLAAILNASIATTSHHLRFLKKNGMAKSRQYGKVVYYSLANEE
                     ILSAVQAFLKLSENSSMKA"
     gene            complement(1193..>1365)
                     /locus_tag="NOB43_002824"
     CDS             complement(1193..>1365)
                     /locus_tag="NOB43_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983606.1"
                     /translation="KSTNLLERLNQEVRRREKIIRIFPNRTSANRLIGAVLMDLHDEW
                     LSSTRKYIKFDQ"
BASE COUNT          484 a          260 c          196 g          425 t
ORIGIN      
        1 tgcttccttt actaataaga tctctacaaa cctaatatag tttggatggt tccattttct
       61 atcataataa aaatccctaa tccaataaat acgataggta caatgattcg ttcatatttt
      121 tctagtgttt cagagacaaa agaaattttc gcaaatttat aactaatata gcaaagaacc
      181 gcaacagaga tagcaaagac gattaaagaa gtgacaattt ctgaaaaaga taacgaggta
      241 aagaaaggaa tataaatccc taaattatcg ccaccagaag caatcgttat taaggaaact
      301 gtccaaaaca aacgattcgt tcctctagat cctagcttct caacgacttc cccttcttct
      361 tcctcctctt cgcccacaaa agcaacacga atccctaaat aaatcggaat tagtcccaga
      421 agaccaatga tccaatcttg aggaataaaa tttagcacat atgctgcaaa caaacttatg
      481 gctaccaaga ttcctgttcc aagatattga ccaaaaaaaa tctgacggag acctttttta
      541 gtatggtttt gagaaaaaat aatcagcaag ataaataaat aatcaatact ggtagaaata
      601 tatacagcga gtgctgataa aatgttttgt aacaaaataa ctacctccaa actaagcttt
      661 catagaacta ttttctgaca actttagaaa agcctgcaca gcggaaagaa tctcttcatt
      721 cgctaaagag taataaacta cctttccata ttgacgtgat ttcgccattc cgttcttttt
      781 caaaaaacgt aaatggtgtg acgttgtagc aatactagca ttaagtatcg ctgctaaatc
      841 acaaacgcac atctccttat acgtttctaa agcatagaaa attttaatcc tagaagaatc
      901 gctaaaacat tttcctaata caagtaaagt tgaaaggtct ttatctttta aattattttt
      961 aacactagct actttttctt tatgtataca agtagttgta catacttctg cagtcattaa
     1021 cttcaccacc tcgttcaaac agacgtttga atgaagtata actatttaaa tattgttttg
     1081 tcaataatat gttaatctgt agacctttca aataaattca acattaataa aacaaggttt
     1141 tagtcaagtc cataatcctg tgtaaaatac tatacaatgt tttaccggtc tctcattgat
     1201 caaacttaat atattttctt gtagaactga gccattcgtc atgaaggtcc ataaggacag
     1261 ctccaattaa tcgattggca gacgttcggt tgggaaaaat ccgaataatc ttttctcttc
     1321 tgcggacttc ctggttcagt cgttcaagaa ggttggtgct tttta
//
LOCUS       DAIGTA010000156         1353 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.167, whole genome shotgun sequence.
ACCESSION   DAIGTA010000156 DAIGTA010000000
VERSION     DAIGTA010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1353
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.167"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..580
                     /locus_tag="NOB43_002825"
     CDS             <1..580
                     /locus_tag="NOB43_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983607.1"
                     /translation="VAALRLIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQ
                     LVSGNFTLKGEGQLTFYLLPTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHY
                     LLASRSYGPYTSELLVSERDSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYRE
                     KANPVLANVLLLDLATLLHANKRPKKIAATKK"
     gene            595..1158
                     /locus_tag="NOB43_002826"
     CDS             595..1158
                     /locus_tag="NOB43_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCI0983608.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
BASE COUNT          458 a          227 c          259 g          409 t
ORIGIN      
        1 agtagccgct ttacgtttga tcgatatctt agcagataca tctgaagaga cgggacagcc
       61 aatcgcttat tggctgacaa ctgatctctc agagattcca caagcatcgt atttgactca
      121 aaacaatgat caactggtat ctggcaactt cacactaaaa ggtgaaggac agttgacttt
      181 ctatctattg ccgacgatag ctgaaatgaa aacagcaatt cgccgcaaag acaaaatcca
      241 accaaccgtg acaatgagca gaaaaacatc tgataagatt caaggtgtgg ctttttatgg
      301 ccattatctc ttagccagtc gttcttatgg tccttatacc tcggaactct tagtgtccga
      361 gcgggactct cctagccgga tcctaaaacg aatcaaattt ccaccgtatt tggaacaaat
      421 cgttgttgta gaagatcgtc tagcagtatt gtttgaaagt ggcgccgcag cgtatcgcga
      481 gaaagccaat cctgtgttag ccaatgtttt attactagac ttagcaacgt tgcttcatgc
      541 aaataagcgt cccaaaaaga ttgctgcaac taaaaaatag tcggacaact caagatgatc
      601 actgttgttc ataaagaacg acaagaaaaa tcatctagcg atgttcgact atgggtttat
      661 ttaggaagta tttctactaa gattcaatat ggctatacag attcggcgaa aaaacaaggc
      721 aatgttaagt ttttgagaat cacagatata caagagggac gtgtaaattg gtccagtgtg
      781 ccttactgtg atattagtaa ttctaaacta gttgatttaa gattggaaga aaatgacatt
      841 ttgatagcaa ggacaggagg aactatggga aaaagtttct tggttaagga aataagtgag
      901 gaatctgttt ttgcttctta cttgattcga attaggttag ttgagaaatt attatcagaa
      961 tacgtagact gcttcttaga ctcgccatta tattggaagt tattagaaaa aatttcttac
     1021 ggaactgggc aaccaaatgt aaatggtaca aatttatcta aactacttat accattacca
     1081 cctttagaag aacaacaacg catgactact aaaatagaaa tgataagaag atctattcgt
     1141 agaatcaatt ttgagtaaat ataacggacc tagcatccat tttataccag atgatgctag
     1201 gtctattatt tatattttat ggaatttaat tgatttgttc tagtgtttta atattattac
     1261 gacagtaaaa aaatagtttg attcttctaa catgaatgac catctagaag tggaaatgta
     1321 taaaagattt attttatgaa gttttcctaa tat
//
LOCUS       DAIGTA010000157         1352 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.168, whole genome shotgun sequence.
ACCESSION   DAIGTA010000157 DAIGTA010000000
VERSION     DAIGTA010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.168"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            11..1350
                     /locus_tag="NOB43_002827"
     CDS             join(11..452,452..1350)
                     /locus_tag="NOB43_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HCI0983609.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          565 a          175 c          235 g          377 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag agaacgcata tttaaaaaag ttagaaacct tgattcaaga
      481 acaagatttg agcaagaaga aatcaaggtt aaaacaatcc ttcagctcaa aaaagaattt
      541 aaattgaatc tattactttc aattgcacaa ttagcgaagt caacttatta ttactgggta
      601 aaaaaattag ataagccaga taaatatagc aagataaagc aagaaattac agcgattgta
      661 aaagaatcaa gaaactctta tggttatcgt agagtcactt tagcgttaaa gatgaaagga
      721 tatacaatca atcataaaac agttagaaaa ttaatgtccc aaatgggact tacctgtcaa
      781 atccgaataa agcgatataa atcttataaa ggaacagtag gaaaaattgc caagaatgtg
      841 ttaaaacgaa atttttcagt agatacaccc aataaaaaat gggtgacaga cgtcactgaa
      901 ttcaagataa aaggaagaaa aatctatcta tctcctatac ttgatttatt taacggagaa
      961 ataattagtt atagtatatc aactagtcca acatataaac tgattgaaga aatgcttcaa
     1021 caagcaatta aaaaaaaggg aactgagggt tcactgattc tacattcaga tcaaggatgg
     1081 cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga ataacattat tcaaagcatg
     1141 tctagaaaag gaaattgctt agataattct gtaatagaaa atttttttgg tgtgcttaaa
     1201 tcagagtttt tttatcgaga aaaattccga tcaattgaga tatttcaaag taaattaaat
     1261 gagtatatta ggtggtataa taacaaaagg ataaaactaa agttaaatgg actatctcca
     1321 gtagaatatc ggaaacagtc cattaaatag tt
//
LOCUS       DAIGTA010000158         1323 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.169, whole genome shotgun sequence.
ACCESSION   DAIGTA010000158 DAIGTA010000000
VERSION     DAIGTA010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.169"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            746..1323
                     /locus_tag="NOB43_002828"
                     /pseudo
     CDS             746..1323
                     /locus_tag="NOB43_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738373.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          463 a          242 c          234 g          384 t
ORIGIN      
        1 cctcagttga acctaatgga aggcgtttgg aagtggctca aggaatcggt catcaacaat
       61 gttttttttg accacgtcca gaaaatcaaa cagtcggtcc gcggtttctt agccgatgta
      121 aacgagcgtc cccttgaggt gattgaccga ctgtgcgtgc ggatgtaaag tatttaattc
      181 aacctatata gcatacaata cctaggctac aaaaattttc tgacaatcag aaaagatgct
      241 atctatgatt gggatgaaac acagaaatta aaagtagtta atgtgattga ctactaagca
      301 tgaagaacca ttaaagcgat caaataataa ctaatgatga gcctagggag aaaagattcc
      361 ctaggctttt tcattaagta caaaaataaa taaccagtgt ttttgaaatt gaacttcaca
      421 caatagaaat accgtcttct aaagtataaa aaacgtttat aaagactatc cgcttattca
      481 ctcattttac agtacttttt ccaacctctt tctagacttc agccagctcc tccgctattc
      541 aagaactgat cgatattcca aagaaaaatt ccactatact tgactctaaa ataaaaaaaa
      601 tgaataaaat agtaaattag aatcattgaa aaatagtctg catcctttag acttaaattg
      661 taagcgaaaa cgtttacgac tatattatat taacaggagg aatatcatga aaaaaaaatc
      721 atcactggtc agtttattaa taggaatggt cgctttagcc atctttttaa tcccgaccaa
      781 agcagcacat gctgacgtca ctgtaacaaa cgattgtacg gacttttcaa gcatccaggc
      841 ttcaattaat gcgaattctt caggacaggg taacaccaat tacttcaata ttgaacctgg
      901 tcaatcagac tcttggagta gactttctcg tactgggttt atcttggcga ttgtccataa
      961 aggaatgcta agaacctatt atacgccaac gagtgcttct tactcttatt aagatggtaa
     1021 actttatcaa aaaaacaatt cagctgaaat cacaccattg aaagccgtag tattctctga
     1081 ggaaaaagct actaaaattg taaatatggt caatctctct gatggtacag ttcaggttgc
     1141 attaagcaaa tggaaaactg gcgggtatgc agattacttt gaactttctc gtccagccgt
     1201 tgagagctgg agcagaaaca atgatccaag aggcttttta gtttcattga gagctaaagg
     1261 cgaaatgaat gaatacatat attatttacc tagcattgaa aatatcggtg gaaattattt
     1321 aac
//
LOCUS       DAIGTA010000159         1252 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.171, whole genome shotgun sequence.
ACCESSION   DAIGTA010000159 DAIGTA010000000
VERSION     DAIGTA010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.171"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            82..>1252
                     /locus_tag="NOB43_002829"
     CDS             82..>1252
                     /locus_tag="NOB43_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HCI0983610.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYS"
BASE COUNT          415 a          247 c          239 g          351 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc ca
//
LOCUS       DAIGTA010000160         1252 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.172, whole genome shotgun sequence.
ACCESSION   DAIGTA010000160 DAIGTA010000000
VERSION     DAIGTA010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.172"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..>1252)
                     /locus_tag="NOB43_002830"
                     /note="aph(2'')-Ia"
     CDS             complement(<1..>1252)
                     /locus_tag="NOB43_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HCI0983611.1"
                     /translation="TEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEI
                     VYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSG
                     FRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGS
                     GYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDE
                     LSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQ
                     NVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDG
                     NNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQD
                     IVEEYYPIETIVYGIKNIKQEFIEN"
BASE COUNT          415 a          217 c           98 g          522 t
ORIGIN      
        1 cattttcgat aaattcctgt ttaatatttt taattccata aacaatagtt tcaataggat
       61 aatattcttc aactatatct tgatattctt ttgctttctc aatatctata tttccataca
      121 ttcttaatat atcttctcca aaatttgttc ctatttcttc ttcactatct tcaagtaagt
      181 atataaaatc acaatattca tctataattc cagaatctcc aaaatcaatt attccagtta
      241 atctattatt gccatctaac aatagatgat tacaactaaa atcattatgg cataaacact
      301 ttttaccctc aaaaactgtt gttgcattta gtctttccat aaaactttct atataatctt
      361 tttctatatc agttaaatca ttataaatag tttcacgcaa caatatatac tcttctaata
      421 cattttgttt attatcaata gtacattcac taatatctgt ataatctaaa ccgtgcattt
      481 gtcttaaaaa actggcaata tctcgtttta acaaattttg ttcttcttct gacatagtag
      541 aataaatttc tggtgttaaa aaagttcctt taatttcttt ataacctagt atagataatt
      601 catcactaat atacgaatat tcaatattag gaatttttac attagtttct aaatttgtat
      661 ttaaaaaatt atatattgct ttttcttttg cataaccttt tttcttatta gtactaaatt
      721 ttgttttaaa aatgtattca ttattaacta aatatgccac actatcataa ccactaccga
      781 ttatttcaat actatctact ttgaaattat caaagtaatg ctcaattaaa tatttcattg
      841 ccttaacatt tgtggcatta tcatcatatc tatattccat taaataacaa tcttcttttt
      901 tgccctcgtg taattcatgt tctggcaaat cttcaataat tctaaaacca gatttttggt
      961 atgcccttat tgctcttgga ttatttttat gagggtctaa aataactgca ttagcatttc
     1021 tttctttttt caaaaattca aaaatcaatt taatatatct tgtaccaatt cctttactcc
     1081 aataatttgg ctctcctata aattgatcca taccatagac tatctcatca gtttttggat
     1141 aatgataatc agtatataac tcatcataca ttttatatat ttgtccatat ccaataggaa
     1201 cattgttata ttcaataatt actctaaaaa cttcatcttc ccaaggctct gt
//
LOCUS       DAIGTA010000161         1188 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.173, whole genome shotgun sequence.
ACCESSION   DAIGTA010000161 DAIGTA010000000
VERSION     DAIGTA010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.173"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            141..398
                     /locus_tag="NOB43_002831"
     CDS             141..398
                     /locus_tag="NOB43_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983612.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="NOB43_002832"
     CDS             complement(630..1061)
                     /locus_tag="NOB43_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HCI0983613.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DAIGTA010000162         1167 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.174, whole genome shotgun sequence.
ACCESSION   DAIGTA010000162 DAIGTA010000000
VERSION     DAIGTA010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.174"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            1..1083
                     /locus_tag="NOB43_002833"
                     /pseudo
     CDS             1..1083
                     /locus_tag="NOB43_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          365 a          249 c          227 g          326 t
ORIGIN      
        1 actcagatgt tgaaagtcaa agaaaagttg actattttag aattaaaacg tacccgtttt
       61 ctctgccatg attgtggacg gaccttttct gcgaaaacgg acttagttga tgaacatcat
      121 caactaacaa aggaactgaa gcaggcgatt ctcatggaac tgcacgaaaa tcaatcacgt
      181 aaactaatcg ctaagaagta cttcgtctcg gatgggacgg tgatacggat cttgcgtgaa
      241 gcaacgaagc attaccagcc acgtatgaac ttccttccga cggtgttgtg tatggatgag
      301 ttcaaatcaa tgaagtctgt ttctggttcc atgagtttta tttgtgttga tgggacaacc
      361 aatcagctat ttacgatcct tgaagatcgc ggactttaca aactaactca atacttcctg
      421 cgctttccta gaaaagcccg tttaaaggtc aaatacctag tgatggacat gaatgccagc
      481 tattgtcagc tgcttaaaac ggtctttcca aatgcggaga tcgtaactga tcgctttcat
      541 attgtctaac atatcaatcg cagcttcaat caattgcgta tccagatcat gaatcgtttt
      601 cgagcctcgc actctgaaaa tcagaagaag taccgtcggc tcaagcgata ttggaaactc
      661 ttactcaaag attccacgac attggagccg ctcaaacggc attatcatcg actgtttaaa
      721 cgaccaatta gtcaaacaga aatcgtcgat gaactgttaa gctacaacga agaattgcga
      781 actgcgtatc atttttgtca attattacgc tattatttcg ttaaacgaga tacggaaggc
      841 tttcaagaaa cccttaaaac aatttcatct acgttacctc agtcgtttaa aaagaaattc
      901 acgatcttcc atcgctacca atcgggcatt tcaaatgcct ttaaagtgtc ccactcaaac
      961 gacgtcacgg aggggctgaa taacaagatc aagctgatta aacgaattgc gtttggttat
     1021 cgcaactttt ataactttcg ggcacggatc tatttacaac aaggtctgat ctttgaaaac
     1081 taaaaaatat gcggcgcata gaacgcgccg catatcggac taagttttat tcaaatttgt
     1141 cttcaccaac aagatttgac gaagagc
//
LOCUS       DAIGTA010000163         1127 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.175, whole genome shotgun sequence.
ACCESSION   DAIGTA010000163 DAIGTA010000000
VERSION     DAIGTA010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.175"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            1..395
                     /locus_tag="NOB43_002834"
                     /pseudo
     CDS             1..395
                     /locus_tag="NOB43_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          405 a          193 c          158 g          371 t
ORIGIN      
        1 gtgtcaaaga tcgaaaagaa atctgtgatg attttaaggc tgtttatcaa gctagctcaa
       61 aggaagaggc aaataccttt ttagggagta tgattgagaa gtagcaaaaa acttatccta
      121 aagtgacgca gtcactgata aaaaatcaag atttattgac tttttatgag tttccgcctg
      181 gtatccgccg aagcatttac tcaactaatt taatcgaatc tttcaagaaa caaatcaaga
      241 aatacagccg cagaaaagag cagtttcaaa atgaagaatc actagagcgt ttcctagtat
      301 ccatctttga tacatacaat caaaaattct taaatagaag ccataaaggc ttccaacaag
      361 tgacggatac attagcttca atgtttactg agtaacccat tattttgcag aaggacgagt
      421 tatttacaca aaattattga cgctccctcc aaattacttc atcaaaacat tgatataatt
      481 tttattatat cagtatttat tcttgataca taaatgagaa aataaatact ttaaatctat
      541 tgactacaag tagtcattaa gtcttcataa gatgtacaat atgacattaa aaaaataaaa
      601 gcttacgacc atccgttaaa tctgacacta aataatggac tgctttcttt tgtattagca
      661 ggttacgttg actatgaata ttcaccagat tatttggaga aacctcttca acacgagaac
      721 aatgatatta attttagatt tgtctacgag tcaaaaagta aaacatggtt agttgatcaa
      781 ttaagcacga taaacacaag cttccatgaa ttacctaaac ctgaaaatga agttgagatg
      841 gtcattaaaa tcttctaaaa aagaagcgtt gaaggggaaa tattcctttc aacgctcttt
      901 tttatatgct tagaaacata aataaattgt atactttctt tttagcccct attacttttc
      961 acgaaaaata tctttttttc gacgctagcg tttctctact tctaatactg tacacagttt
     1021 ttgtattatt gaaaaattac tcattattta gcattaatcc acatcgtttt atcaatcgac
     1081 cttcatacta aactacttta aagtcatctt ccttctcgtt tttcatt
//
LOCUS       DAIGTA010000164         1090 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.176, whole genome shotgun sequence.
ACCESSION   DAIGTA010000164 DAIGTA010000000
VERSION     DAIGTA010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.176"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            5..979
                     /gene="bsh"
                     /locus_tag="NOB43_002835"
     CDS             5..979
                     /gene="bsh"
                     /locus_tag="NOB43_002835"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCI0983614.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          383 a          135 c          187 g          385 t
ORIGIN      
        1 aactatgtgt acgtctatta cttatgtaac aagtgatcat tattttggaa ggaattttga
       61 ttatgaaata tcttacaatg aagtagttac tgttactcca agaaattata agttgaattt
      121 tcgaaaggta aatgatttgg atactcatta tgcaatgatt ggtattgccg ctggtatagc
      181 tgactaccct ctttattacg atgcgacaaa tgaaaaagga ttgagtatgg ctgggctaaa
      241 tttttctggg tatgctgatt ataaagaaat acaagaaggg aaagacaatg tatctccttt
      301 tgaatttatt ccttggattt taggacaatg ctcaacagta ggagaaacta aaaaattgtt
      361 aaaaaatatc aatttagcaa atataaatta tagtgatgaa cttcctttat cccctttaca
      421 ttggctatta gctgataaag aaaaatcaat tgtcattgaa agtatgaaag atggacttca
      481 tatatatgat aaccctgtgg gcgttcttac caataatcct tcatttgact atcaattatt
      541 taatttaaac aattatcgtg tcttatcgag tgaaactcct aaaaataatt tttcaaatca
      601 aataagtttg aatgcctata gccgcggtat gggagggata ggcttgcctg gagatttatc
      661 ctcagtatct cgttttgtta aagcgacttt tacgaagctg aattctgtat ctggagattc
      721 agagtcagaa agtattagtc aatttttcca tatcttaggt tcagtagaac aacaaaaagg
      781 tttgtgtgat gttggtgatg gaaaatatga atatacaatt tattcttctt gttgcaatgt
      841 tgacaaagga atctattatt atcgaacata tgaagacagt caaattactg caattgatat
      901 gaataaagaa gacttagata gtcataagtt aattagttat ccaattatag aaaaacaaca
      961 aattaaatat ataaattagt taatgtgttg tgattgatta tttaatatag atataataca
     1021 aaaaggcaaa gatattttca aaacattttt tcttgatgtg atatccttgt cttttttgta
     1081 atgtttttaa
//
LOCUS       DAIGTA010000165         1068 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.177, whole genome shotgun sequence.
ACCESSION   DAIGTA010000165 DAIGTA010000000
VERSION     DAIGTA010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.177"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>1068
                     /locus_tag="NOB43_002836"
     rRNA            <1..>1068
                     /locus_tag="NOB43_002836"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          281 a          249 c          324 g          214 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggc
//
LOCUS       DAIGTA010000166         1061 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.178, whole genome shotgun sequence.
ACCESSION   DAIGTA010000166 DAIGTA010000000
VERSION     DAIGTA010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.178"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(36..992)
                     /locus_tag="NOB43_002837"
     CDS             complement(36..992)
                     /locus_tag="NOB43_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983615.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DAIGTA010000167         1050 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.179, whole genome shotgun sequence.
ACCESSION   DAIGTA010000167 DAIGTA010000000
VERSION     DAIGTA010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.179"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            89..1024
                     /locus_tag="NOB43_002838"
     CDS             89..1024
                     /locus_tag="NOB43_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0983616.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYTGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRVGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT          366 a          166 c          238 g          280 t
ORIGIN      
        1 gttataaaaa tgaacattgc atagtagaga ttctttgatt atactaattc aaggttatat
       61 gaaaaaagag aaatgagatg gatgatttat gaaactttgg atgaaaatcc ttttaggcgt
      121 cgctttagct ctgattgttg cgttagtgtt tgcagggaat tatttttata attatgctgt
      181 tgtgccttct gagaaagact ttttagacga agatacacct ggtacaacac agacatccaa
      241 agaaacggat gcacataaat ggtttagttc aaaagaaaac cgaagcgatt ggaccatcac
      301 ttcaaaagac ggtctgaaat tatcagcgat ttatcttcct gctgaaacga aaagtgaaaa
      361 aacagctctt gtggctcatg gctatatggg aaacgctgaa acgatgacca attacgcaaa
      421 gatgtttcat gatatgggtt acaatgtcct tgttcctgat gcaagaggac atggaaaaag
      481 cgaaggggat tacactggat ttggatggcc agagcgtaaa gactatgtac agtggataaa
      541 caaagtgcta gaaaacaatg gaaaatcgca agaaatcgtt ctatacggtg tcagcatggg
      601 agcagcaaca gttatgatga ctagcggaga aaaactacca gataatgtga aagcaatcat
      661 tgaagattgc ggttattctt ccgttcatga tgagcttgct tatcagctag acgatatgtt
      721 tagtcttcca gcatttccgc ttatgcaagt aacgagtcta gtgacaaaag tccgtgttgg
      781 ctactttttc ggtgaagcaa atgcagtgga acaattgaag aaaaaccagc gcccaatgct
      841 ctttatacat ggagacgaag atacatttgt accatttgaa atgttagata aggtctatcg
      901 tgcaacgaag ggaccaaaag aaaagtatgt tgtaaaagga gccgagcatg cggaagcata
      961 caagacagat cctgaaaaat atcagcaagt agtccaacaa tttttaagcc aatatgttca
     1021 ttgaacgagt ttaaaagtag gggatgaaaa
//
LOCUS       DAIGTA010000168         1035 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.180, whole genome shotgun sequence.
ACCESSION   DAIGTA010000168 DAIGTA010000000
VERSION     DAIGTA010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.180"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..>1035)
                     /locus_tag="NOB43_002839"
     rRNA            complement(<1..>1035)
                     /locus_tag="NOB43_002839"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAIGTA010000169         1021 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.181, whole genome shotgun sequence.
ACCESSION   DAIGTA010000169 DAIGTA010000000
VERSION     DAIGTA010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.181"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..518
                     /locus_tag="NOB43_002840"
     CDS             <1..518
                     /locus_tag="NOB43_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0983617.1"
                     /translation="VLAAAIANGGDEKDIQPGLNYYKKMAEKGRLSTVDASVANLEKG
                     EIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISGYTTLINKNAPHPNAAKLAREY
                     ILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAYEAAVPVEDNEAWNKTSVELPE
                     LWQAEVLTYAK"
     gene            508..>1021
                     /locus_tag="NOB43_002841"
     CDS             508..>1021
                     /locus_tag="NOB43_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HCI0983618.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKF"
BASE COUNT          298 a          214 c          253 g          256 t
ORIGIN      
        1 ctgtattggc tgcggcgatt gccaacggag gtgacgaaaa ggatattcag ccaggtctga
       61 attactacaa aaaaatggca gaaaaaggcc gtttgtccac cgttgatgcc agcgtagcaa
      121 atcttgaaaa aggtgaaatc gatgtggcag ttgtttggga cttcaatgga ctaaattatc
      181 gtgaccaaat tgactccgag cgttttgagg taactgtgcc aacagacggc tccatcatta
      241 gcgggtatac aaccttaatc aataaaaatg cccctcatcc caatgcggca aagctagcac
      301 gggaatatat tttatctgat gaagggcaaa tcaatttggc aaagggctat gcgcgaccta
      361 ttcgcaaggt agagctgcct aaagaagtag ctgaaaaatt actgccggag gatgcttatg
      421 aagcggcggt gccagttgaa gacaatgaag cttggaacaa gacctctgta gagcttccag
      481 agctttggca ggcggaggta ctgacctatg caaagtagac ttgacaaact gattgtagtt
      541 atactagacg gctgtcgcta cgacacagcc gtcgcccagc ttgggttcat gaatcattta
      601 gttgagcacc agcaagcaag cttattgaag gtaaaaagtg agctgcccag caattcacgt
      661 ccgttatacg aagtactgat gaccggcgtt ccagcctatg aaaatggcat ctatagtaat
      721 taccatgctc agcgatccaa agagtggtcg ctgtttgaat tagttaagga agctggcgga
      781 aaaacaggag ccgccgctta ccactggtac agcgagttgt acaatcaagc cccctataat
      841 cgtttggttg atcgcatcca gcatcaggag gagcgactga ttcagcatgg catcttttat
      901 agtgaggaca cttaccctga ttcgcattta tttgcggatg cccattattt agtgaatcag
      961 tatcagccag actttttggt cgtacattcg atgaatattg atgatgtcgg tcacaaattt
     1021 a
//
LOCUS       DAIGTA010000170          979 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.182, whole genome shotgun sequence.
ACCESSION   DAIGTA010000170 DAIGTA010000000
VERSION     DAIGTA010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.182"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            108..>979
                     /locus_tag="NOB43_002842"
     CDS             108..>979
                     /locus_tag="NOB43_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HCI0983619.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVT"
BASE COUNT          428 a          105 c          158 g          288 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaac
//
LOCUS       DAIGTA010000171          949 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.183, whole genome shotgun sequence.
ACCESSION   DAIGTA010000171 DAIGTA010000000
VERSION     DAIGTA010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.183"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..461)
                     /locus_tag="NOB43_002843"
     CDS             complement(<1..461)
                     /locus_tag="NOB43_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0983620.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
     gene            complement(747..>949)
                     /locus_tag="NOB43_002844"
     CDS             complement(747..>949)
                     /locus_tag="NOB43_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0983621.1"
                     /translation="LIYDEIAIDPYKGEQKTGDLSGIWSSGFKYAGTTYRVAYEIIEN
                     KVIPVLLCGTHENFYEQLKKLI"
BASE COUNT          307 a          181 c          128 g          333 t
ORIGIN      
        1 ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa ctcatcaaat
       61 aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt atattggtct
      121 ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata gaggttattg
      181 attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc agtcacagta
      241 ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa gttcatatgc
      301 gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat caaggttctt
      361 tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact tttacctacg
      421 ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc tcttttcttt
      481 tagcaatatt catttgatac tattataaca tatttatttt tagttactac caaaaaaaag
      541 atatatatgt actaccttat aattaataag taaaaggtag tacataaata aggaaaagct
      601 gaaatatatt gatttatagc tttcctcaaa gtaatgacgt tatttaattt atcgagaagc
      661 agagaatact cgcgacttta gtcatgtaga tgaatcagat cttcgataaa aaagaagccg
      721 tccttcttaa gaacgacaac aaatcactag attaattttt tcaactgttc ataaaagttt
      781 tcatgcgttc cacataacaa tactggaata accttgtttt ctataatctc gtaagctact
      841 ctatatgttg tgcccgcata tttgaaccca ctagaccaaa tacctgataa atccccagtt
      901 ttttgttcac ccttatatgg atcaatcgca atttcatcat aaattaaat
//
LOCUS       DAIGTA010000172          942 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.184, whole genome shotgun sequence.
ACCESSION   DAIGTA010000172 DAIGTA010000000
VERSION     DAIGTA010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.184"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..354
                     /locus_tag="NOB43_002845"
     CDS             <1..354
                     /locus_tag="NOB43_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0983622.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
     gene            355..903
                     /locus_tag="NOB43_002846"
     CDS             355..903
                     /locus_tag="NOB43_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983623.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
BASE COUNT          380 a          131 c          201 g          230 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacagagtag aggaagaaca
      541 aaaaaagttg gcgcaccaat cagaaagttt gataaggttt attccaccaa gcatccttta
      601 aaactgtcga ctttgttaaa tgcgacttcc agagttttag tagaaaagta tgagactaat
      661 atgacaagag atgaattgct tagaaaagct ttagatgagt atattaaaca gaatcttacg
      721 caagaagata agcaagattt gtttaatgac gtggtgaaag aactagactt gttcagagaa
      781 aaatatccaa ttgttccaga attagatgat cgtggagaaa taataagaac taccagtcag
      841 ataaaacaag ataccgaaga ctcactgcgc aaagggtggg gaatgaataa taaagttaga
      901 taataatcaa agaagaacta agtaactacc tttaaacggt ag
//
LOCUS       DAIGTA010000173          927 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.185, whole genome shotgun sequence.
ACCESSION   DAIGTA010000173 DAIGTA010000000
VERSION     DAIGTA010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.185"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            54..927
                     /locus_tag="NOB43_002847"
                     /pseudo
     CDS             54..927
                     /locus_tag="NOB43_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          362 a          153 c          177 g          235 t
ORIGIN      
        1 acagaaaaat taaggtgtgt agactagaag aaaacatacc aggaggaatt tttatgtcta
       61 agagaacacg aagaactttt tcacaagaat tcaagcaaca aatcgtcaat ctttacttag
      121 ctggaaagcc acgtgtagaa atcattcgag aatatgaact aacggcttca gcatttgaca
      181 aatgggtaaa gcaatctaaa acgagtggtt cattcaaaga aaaagataat cttacgcctg
      241 aacaaaaaga attgttagaa ctacgtaaaa gaaaccagca attagaaatg gaaaatgata
      301 ttttaaagca agcagcgctg atattcggac gaagagacaa gtaatcgatg cgaataagca
      361 tctttaccct atatcagcga tgtgcagaat attaggtcta tcacgtcagt cctattatta
      421 tcaatcaaaa ccaaagaaag acgaatcaga acttgaagaa gtagtcgctg aagaatttat
      481 ccgcagccga aaggcctacg gctcaagaaa aataaaaaaa gccttatcaa aacgaggcat
      541 tcagatcagc cgacgaaaaa ttagtagaat catgaaaaat agaggattaa aatcgagcta
      601 tactgttgct tattttaaag tacatcattc tacttgcaat gaagccaaaa cgacaaacgt
      661 attgaatcgt aaattcttaa gagacaaccc attagaagcg atcgtaacag acttgactta
      721 tgtacgagtc gggaaaaaat ggaattatgt ctgtttcatt ttggatctgt tcaatcgaga
      781 aattctcggc tattcttgtg gagaacataa agatgccgtt ctagtaaaaa aagcatttag
      841 ccgtatcaaa caacctctga cagaggttga gatttttcat actgatcgtg gaaaagagtt
      901 tgataaccaa gctattgatg aattatt
//
LOCUS       DAIGTA010000174          907 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.186, whole genome shotgun sequence.
ACCESSION   DAIGTA010000174 DAIGTA010000000
VERSION     DAIGTA010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.186"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            72..>907
                     /locus_tag="NOB43_002848"
     CDS             72..>907
                     /locus_tag="NOB43_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HCI0983624.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QA"
BASE COUNT          303 a          165 c          178 g          261 t
ORIGIN      
        1 ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca actgagagga
       61 cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag aaagatttga
      121 tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc gtcgatgctg
      181 ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta gatggaaacg
      241 ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt gaacaataca
      301 atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa aactgtcgaa
      361 cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg aatcatgtca
      421 gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt gcgaaaaatt
      481 gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc tacttaccaa
      541 agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt tcgcacgctt
      601 ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa ttaattgatg
      661 tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc gctaatcctg
      721 aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt accaaacgta
      781 ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac atgaatcaag
      841 cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga cagaaaagtc
      901 aggcaga
//
LOCUS       DAIGTA010000175          870 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.187, whole genome shotgun sequence.
ACCESSION   DAIGTA010000175 DAIGTA010000000
VERSION     DAIGTA010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.187"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..>870)
                     /locus_tag="NOB43_002849"
     CDS             complement(<1..>870)
                     /locus_tag="NOB43_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HCI0983625.1"
                     /translation="LMENQRTEYIQADDYERSESRQSQRNGYYERDFTTRVGTLELKV
                     PRTRDGEFSPTVFERYQRNEKALLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVS
                     SLTEQLDPMVNEWQNRSLSGTNYPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDR
                     EIIGFMIQNEESDDTWSIFFEYLKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRC
                     QVHFLRNIFSSIPKKNSKPFREAVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACE
                     ILDNGFEDAFQYTV"
BASE COUNT          235 a          194 c          167 g          274 t
ORIGIN      
        1 aaccgtgtat tgaaaggcat cttcgaagcc attatccaat atttcgcagg cttttgtata
       61 tttaggctgg tcgatatatt caccgactaa ggcattctta gctgttcgag cgagttcaat
      121 atccgtaaac ttaaagatcg cttttactgc ttctctaaac ggttttgaat tcttttttgg
      181 aatggaactg aagatgtttc ttaaaaaatg gacctggcat ctctgccaac ttgcgttggt
      241 aaatgactta cgaatcgcag acactaggcc tttatgggca tcagaaatga tgagttctgt
      301 cccctttagg ccgcgttctt ttaagtattc aaagaagatg gaccatgtgt catcactttc
      361 ttcattttga atcatgaagc caatgatttc acggtcgcca ccttctgtta tcccgatcgc
      421 aatatggcag cttttagaaa gcactcgatg gtcctcacgg acttttatgt agagaacatc
      481 agtcatcaga taaggataat tcgtacctga gagtgaacgg ttctgccatt cgttgaccat
      541 cgggtctaac tgctcagtca ggctagaaac aaaagatttc gatacagatt ttccacatag
      601 ctcttcaaca atctttgaaa ctttacgtgt cgaaacgccc gaaacataca tctcaagcat
      661 tgaagcgagc agtgcctttt catttcgctg ataacgctca aacaccgtcg gtgaaaattc
      721 accatcacgt gttctaggca cttttaattc gagtgtaccc acacgagtcg taaagtctcg
      781 ctcataatag ccatttcttt gactctgacg actttctgaa cgttcatagt catcggcttg
      841 aatatattct gttcgttgat tttccatcaa
//
LOCUS       DAIGTA010000176          867 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.189, whole genome shotgun sequence.
ACCESSION   DAIGTA010000176 DAIGTA010000000
VERSION     DAIGTA010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.189"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..210)
                     /locus_tag="NOB43_002850"
     CDS             complement(<1..210)
                     /locus_tag="NOB43_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0983626.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
     gene            complement(309..623)
                     /locus_tag="NOB43_002851"
     CDS             complement(309..623)
                     /locus_tag="NOB43_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983627.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(691..837)
                     /locus_tag="NOB43_002852"
     CDS             complement(691..837)
                     /locus_tag="NOB43_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983628.1"
                     /translation="MILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
BASE COUNT          285 a          172 c           90 g          320 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg tttgtgagaa taattcattg
      421 aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc tattatttct
      481 gcttctaatt caaataaatc tagtgacgaa ctaaaatcat aaatcatgtc atattgaata
      541 aaaaaatcaa gaaaaagttg ctcaaactct tccttattta tcactaatgt ttcaaacgga
      601 acaactttat tttcctcagc cattctccca gttccatttt caaaaatcac aaaactgata
      661 ttaccttaaa aactactaac aaaataaaac ttataaagta aatggcaacc caactatgta
      721 accattctct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
      781 gtaatttact gtttcttctt tgccactttc aatatactct ggattatcca atatcatatc
      841 atactcataa agttcttcac catcctt
//
LOCUS       DAIGTA010000177          857 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.190, whole genome shotgun sequence.
ACCESSION   DAIGTA010000177 DAIGTA010000000
VERSION     DAIGTA010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.190"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..223)
                     /locus_tag="NOB43_002853"
     CDS             complement(<1..223)
                     /locus_tag="NOB43_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI0983629.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDED"
     gene            complement(223..486)
                     /locus_tag="NOB43_002854"
     CDS             complement(223..486)
                     /locus_tag="NOB43_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0983630.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            720..>857
                     /locus_tag="NOB43_002855"
     CDS             720..>857
                     /locus_tag="NOB43_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI0983631.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT          277 a          169 c          114 g          297 t
ORIGIN      
        1 catcttcatc taccttataa acaacccggt gttgtctatt caatcttcta gaatacctac
       61 cttcatgtgt aggttttaac ttctcaaatg attgggtagg gagataggga tcttccttta
      121 aagtctgaat aaccttctca aattgaggtt tcaaattaga ctgtttgatt ttctttaaat
      181 cagctttagc cgagttttta atcatcacag aatagttatt cattataagt tatcccaatc
      241 aatttcatca acattagtaa atccactatc atctttttct cgcttacgaa caacacccaa
      301 agtgcctatt tgctcaagta atagcgtttc tttgattgct ttccaatcat ccaaaccaat
      361 aagcaccgca ttattttcac tgcgctcact aatgatttca atttccgtat gattctcatt
      421 tacatctttc aacaacttat aaaaattttt ccgtgctgag ctaggattta agactgtttt
      481 tgccatatct actccccctc taatttatat ctccattcta acgtacttaa ttaagtacgt
      541 aaattcgatt gttttgttta aattggagta ccaaaacagc attgtaaagt gttatccgtt
      601 tcctttatac ccgtggtgct agttaatttt ttcctagagg aaaatgtcta aacatgttgg
      661 taaatcaaca aaaaaacgca tagagtagtc tcaaaactcc caagaaatga ggactacata
      721 tgcgttcatc aaaatatact gaacattata cagatacttt tataacattc aaggaaatta
      781 tgagaactgt ttctaacata taccacaatt gtgtaccaga taagattaaa aaccgaagaa
      841 atactgatca actgaag
//
LOCUS       DAIGTA010000178          854 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.191, whole genome shotgun sequence.
ACCESSION   DAIGTA010000178 DAIGTA010000000
VERSION     DAIGTA010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.191"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            67..>854
                     /locus_tag="NOB43_002856"
     CDS             67..>854
                     /locus_tag="NOB43_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HCI0983632.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNI"
BASE COUNT          312 a          160 c          158 g          224 t
ORIGIN      
        1 ccatataaca gtccttttac ggtacaatgt ttttaacgac aaaaacatac ccaggaggac
       61 ttttacatga cccaagtaca ttttacactg aaaagcgaag agattcaaag cattattgaa
      121 tattctgtaa aggatgacgt ttctaaaaat attttaacaa cggtatttaa tcaactaatg
      181 gaaaatcaac gaacagaata tattcaagca aaagaatatg aacgaacaga aaaccgacaa
      241 agtcaacgaa atggctatta tgagcgcagc tttacgacac gtgtaggcac gctagaatta
      301 aaagtaccca gaacacgtga tggccatttt tcacccacag tgtttgaacg ttatcaacga
      361 aacgaaaaag ccctcatggc ttcaatgttg gaaatgtatg tatcaggcgt ttcaactcgt
      421 aaagtatcaa aaattgtgga agaactttgt ggtaaatccg tctctaagtc cttcgtttct
      481 agcttaacag aacagctaga acctatggtt aacgagtggc agaatcgttt attatcagaa
      541 aaaaattatc cttacttaat gaccgatgta ctctatataa aagtacgaga agaaaatcga
      601 gtactctcaa aaagctgtca tatagcgatt ggaataacca aagatggcga ccgtgaaatt
      661 atcggcttca tgattcaaag tggcgaaagc gaagagacct ggacaacatt ttttgaatac
      721 ctaaaagaac gcggtttaca aggtacggaa ctcgttattt ctgatgcgca caaaggatta
      781 gtctctgcca ttagaaaatc cttcaccaac gtaagttggc aaagatgcca agttcacttc
      841 ctaagaaata tctt
//
LOCUS       DAIGTA010000179          834 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.192, whole genome shotgun sequence.
ACCESSION   DAIGTA010000179 DAIGTA010000000
VERSION     DAIGTA010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.192"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            120..>834
                     /locus_tag="NOB43_002857"
     CDS             120..>834
                     /locus_tag="NOB43_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0983633.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLSVDDKVHPLKLSWSIDRITIVG
                     KLKENIYYHTPNDVLILDFEQLMRLNEGNGYLRSVSNNGWQLLDQHEENIAYIEILKW
                     QEGKGRIDFNPNKISQFLASSMKNFIHDLFIEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRNGKLETAYWGSRSSERQIRMYNKKLEQEKKRKIVPKEIVSWWRLEMQ
                     LRRGKATDWHAMVRESLDSF"
BASE COUNT          279 a          117 c          180 g          258 t
ORIGIN      
        1 acgaatattt ttaggtttct tcaagactag agattttttg gtaatgaatt tttaagagtt
       61 acgtgaactt ttgaaaattc tttccagaag tctctttttt ctttgaggag gaactaaatt
      121 tgagtaaaaa aggcacgatc ataaatgagt gggaaaaatt aacagccccc tctaacaggc
      181 ggttaagtgt tgacgataag gtacaccccc taaaattaag ttggtcaatc gatcgaatta
      241 caatcgtcgg aaaactgaaa gaaaatattt attatcacac tccaaatgat gtgttgattt
      301 tagattttga acagcttatg cgcctaaatg aaggtaacgg ttatttaaga tctgttagta
      361 ataatggttg gcagttgtta gaccaacatg aagagaatat tgcttatatt gaaattttaa
      421 aatggcaaga ggggaaaggg cgtatagact tcaatccgaa taagattagt caattcttag
      481 ctagttccat gaaaaatttt attcatgatt tgtttatcga acctcacttt tcacgtgcag
      541 atattgcttg cgacattatc gatgtacctg atgagtttat tacacaatat cgggtagttg
      601 atccagtttc ttttaagcct atttatggac ggaatggaaa attagagacg gcatattggg
      661 gatctcgctc ttctgaacgt caaattcgga tgtataataa aaaactggaa caagagaaga
      721 aaagaaaaat tgtgccaaaa gaaatcgtga gttggtggcg gttagaaatg cagctaagac
      781 gtggcaaagc aacagattgg catgcgatgg ttcgggaaag tttagatagc tttg
//
LOCUS       DAIGTA010000180          813 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.193, whole genome shotgun sequence.
ACCESSION   DAIGTA010000180 DAIGTA010000000
VERSION     DAIGTA010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.193"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..809)
                     /locus_tag="NOB43_002858"
     CDS             complement(<1..809)
                     /locus_tag="NOB43_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983634.1"
                     /translation="MKKLVKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAKTGISMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGATLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTNRQKQQLSLKQTRKEKQSK"
BASE COUNT          270 a          200 c          157 g          186 t
ORIGIN      
        1 tttttcgact gcttctcttt cctcgtctgc ttaagggaca gctgttgctt ttgtcgatta
       61 gtcagcataa aggtagttaa agcaattccc accataaaca gcaaatacaa aaccatcaca
      121 gcgctagcca aatggccgtt ttcgttcatc cgccgcagca tatagatgcg taccgtctga
      181 aatcgaccgc caatcaacag gttcgtcagc atgtactccc caaaaaccga agaaaaaatc
      241 atcagagaaa ccagggtcgc accgatacgg atgttgggaa acagcacctg gataataatc
      301 gtagacatcg gggcgcccaa ggtttctgct gcatccacta attccttcag attaattaag
      361 cgcatctggt tgttaagact aagatagaca atcggcaacg ccgtaataaa caatgcacct
      421 accaacacta caaacattga gataccagtt ttagcatacg ttcgaagcaa agccgttacc
      481 aaaatcactc ccggtaaagc atacggcagc aggagcagct tttccagcca acgattcaaa
      541 cgagggaaat acaaatgaat ccaaataatg gttggaatca tcaacaacag aatcgtcacc
      601 aagaccacac ctgctaataa aagtgagcga cccaccgcag caataaattc cctgtccgtc
      661 agcagctgtt ggaaccattg caaggtaaaa tcactaggta aaagcgattt tgaccatttt
      721 gtggagctgg catacaaaat cgttccaata atcggcagca agtaatacag gacaaagcag
      781 aacaaaatcg gttttactaa ctttttcacg ttt
//
LOCUS       DAIGTA010000181          812 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.194, whole genome shotgun sequence.
ACCESSION   DAIGTA010000181 DAIGTA010000000
VERSION     DAIGTA010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.194"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..808)
                     /locus_tag="NOB43_002859"
     CDS             complement(<1..808)
                     /locus_tag="NOB43_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983635.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSK"
BASE COUNT          272 a          200 c          157 g          183 t
ORIGIN      
        1 ttttcgactg cttctcttcc ctcgtctgct taagggacag ctgttgcttt tgtcgataag
       61 tcagcataaa ggtagttaaa gcaattccca ccataaacag caaatacaaa accatcacag
      121 cgctagccaa atggccgttt tcgttcatcc gccgcagcat atagatgcgt accgtctgaa
      181 atcgaccgcc aatcaacagg ttcgtcagca tgtactcccc aaaaaccgaa gaaaaaatca
      241 tcagagaaac tagggtcaca ccgatacgga tgtttggaaa cagcacctgg ataataatcg
      301 tagacatcgg ggcgcccaag gtttctgctg catccactaa ttccttcaga ttaattaagc
      361 gcatctggtt gttaagacta agatagacaa tcggcaacgc cgtaataaac aatgcaccta
      421 ccaacactac aaacattggg ataccagttt cagcatacgt tcgaagcaaa gccgttacca
      481 aaatcactcc tggtaaagca tacggcagca ggagcagctt ttccagccaa cgattcaaac
      541 gagggaaata caaatgaatc caaataatgg tgggaatcat caacaacaga atcgtcacca
      601 agaccacacc tgctaataaa agtgagcgac ccaccgcagc aataaattcc ctgtccgtca
      661 gcagctgttg gaaccattgc aaggtaaaat cactaggtaa aagcgatttt gaccatttag
      721 tggagctggc atacaaaatc gttccaataa tcggcagcaa gtaatacagg acaaagcaga
      781 acaaaatcgg ttttattaac tttttcacgt ct
//
LOCUS       DAIGTA010000182          795 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.195, whole genome shotgun sequence.
ACCESSION   DAIGTA010000182 DAIGTA010000000
VERSION     DAIGTA010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.195"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            98..628
                     /locus_tag="NOB43_002860"
     CDS             98..628
                     /locus_tag="NOB43_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983636.1"
                     /translation="MISDNKWEINLKRFISEYIYTIETKSSFSLNEDSDPLKKYTIQC
                     KKNKDEKLFVIRPDLMKSNTHYIKEKPKDCDYIIISEANKTVFLIELKSSAQTSPAKE
                     ISEQIDGGYKWLQHLSFLTKYDFTEFSYKIIKVCCKFEARQDRKNLFKPNEYGIYNMN
                     GPKLDLRELYRKCNDL"
     gene            complement(623..>795)
                     /locus_tag="NOB43_002861"
     CDS             complement(623..>795)
                     /locus_tag="NOB43_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983637.1"
                     /translation="KGRPKLYSADTKNPQRRLVYENIVKDLNEGVSISKIAKNYNVTR
                     QTIYRIKKDLNL"
BASE COUNT          310 a           96 c          123 g          266 t
ORIGIN      
        1 tttctaacat cagttattat gataattttg atgatgtcaa ttatgattta caggaaagat
       61 ataatgattt aatcgaagaa ttagaggaga gaggagaatg atttcagata ataaatggga
      121 aataaatctc aaaagattta tttcagaata tatatatacg attgaaacta aatctagttt
      181 ttctcttaat gaagacagtg atcctctaaa aaaatacact attcaatgta agaaaaataa
      241 agatgaaaaa ttgttcgtaa taagaccaga tcttatgaag agtaataccc actatataaa
      301 agaaaaacct aaagattgtg actacatcat cataagtgaa gcaaataaaa cagtatttct
      361 gatagaactt aaaagctcag ctcagacttc ccctgcaaaa gaaattagtg aacaaattga
      421 tggtggatat aagtggttac aacatcttag ttttctaaca aaatatgatt ttactgaatt
      481 cagttataaa attattaagg tatgttgtaa atttgaggca agacaagatc gtaaaaatct
      541 ttttaaacct aatgaatatg gtatttataa tatgaatggt ccaaaattag acttaagaga
      601 gttgtataga aagtgtaacg atctataaat tcaaatcttt tttaattcta tatattgttt
      661 gtctagtaac gttataattc tttgcaatct ttgaaataga gacgccctca ttcaagtcct
      721 taacgatgtt ttcataaact aaacgtcgtt gaggattttt tgtatctgca ctatagagtt
      781 ttggacgacc tttat
//
LOCUS       DAIGTA010000183          792 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.196, whole genome shotgun sequence.
ACCESSION   DAIGTA010000183 DAIGTA010000000
VERSION     DAIGTA010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.196"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(62..262)
                     /locus_tag="NOB43_002862"
     CDS             complement(62..262)
                     /locus_tag="NOB43_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0983638.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT          256 a          133 c          122 g          281 t
ORIGIN      
        1 aattttttcg tacaaaaaaa ccgtcttttc tttcgaaaag acggttaaaa gtcaattttt
       61 attaagcttt aacaatgttt gttgcttgag ggccacgttg accatcttca acatcgtaag
      121 acactgcttg gccttcttct aaagttttga agccgtcacc ttggatagct gaaaaatgtg
      181 caaatacatc atttccatct tcaccagtga taaagccaaa acctttgtct gcgttgaacc
      241 attttactgt accgttattc ataaataaat tcctcctgat acgtatcaat gtacgttttt
      301 tcgttgcaat aaatatttga taggcaaaag gagttttatc tatgtagata tatcgctcaa
      361 attacgtttc aaaatagatt actcatttaa tatatcatgc tttttctaat aacacaagga
      421 taatgcaatg aaatataaaa ttcattgtct tctattgtct tcgaatcgaa gaaaaagttg
      481 aataaccgcg attgattcac tttttgtttt cttgtttatt tgcttttatc tgcaactttt
      541 gactttaaaa tttcttaact atgaaaacct ttcaattggt ggtatactta taaatggaat
      601 ttcgttatca acgcgttcgt tgcctttcag caagtattta aagaaaggag aatggctatg
      661 acattctata acaaagatat acaatatcga gtaaccttgg atacagattt gaatctattt
      721 gtcgtttttg acaaagaaaa taccaatcat gtagcgacag gtgttacgat cgaacaagca
      781 gtgcaagaat ta
//
LOCUS       DAIGTA010000184          791 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.197, whole genome shotgun sequence.
ACCESSION   DAIGTA010000184 DAIGTA010000000
VERSION     DAIGTA010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.197"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..782
                     /locus_tag="NOB43_002863"
     CDS             <1..782
                     /locus_tag="NOB43_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0983639.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DAIGTA010000185          790 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.198, whole genome shotgun sequence.
ACCESSION   DAIGTA010000185 DAIGTA010000000
VERSION     DAIGTA010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.198"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..>790)
                     /locus_tag="NOB43_002864"
     CDS             complement(<1..>790)
                     /locus_tag="NOB43_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="HCI0983640.1"
                     /translation="VLNEHGLESVNNEYYENLEKRTNLYSNDPSKMKYGKINYQEFVQ
                     NAIEATLEKCEVNSFEDFSDHLAKEYNIEVYQFSKTNNKLGYVLYKQDVNFYERRGEL
                     ITLGRDKQSRKEKSQYVERTFSARKLGKRYSFESVSEQLEKNLEESHIKNFFNMEREQ
                     VMSLISGVNYKTGELNVPFVELDSIAQKQFSDREGDEKFIKYDDFLREVDKHFVNTMS
                     LEDDQEYTIKLHTDVNPQTLRSAKSKTISIKKTDQKELFLPAKGF"
BASE COUNT          231 a          148 c           99 g          312 t
ORIGIN      
        1 aaaacccttt gccggtagaa ataactcttt ctgatcagtc tttttaatag aaattgtttt
       61 acttttcgca ctacgtaaag tttgaggatt cacatccgta tgaagtttaa tcgtgtattc
      121 ttgatcatct tctaaagaca ttgtatttac aaaatgcttg tctacctctc gcaagaagtc
      181 atcatattta atgaattttt catcgccttc acggtcgcta aattgctttt gtgcgatgga
      241 atctaattcc acaaacggta catttaactc accagttttg taatttactc cactaattag
      301 cgacataact tgctctcttt ccatattaaa aaaatttttt atatgtgatt cttctaaatt
      361 cttttcaagt tgttcagaaa cagattcaaa tgaatatctt ttccctaact ttcttgcact
      421 aaaagtacgt tcgacatact gacttttttc ttttctagat tgtttatctc ttcctaaagt
      481 aattaactca cctctacgct catagaaatt tacatcttgt ttgtaaagaa catagccaag
      541 tttgttattt gtttttgaaa attgataaac ttcaatgtta tattcttttg ccaaatgatc
      601 cgaaaaatct tcaaaagaat tcacttcgca tttttccaac gttgcttcga tcgcattttg
      661 cacaaactct tgataattaa tttttccata tttcatctta gaaggatcgt ttgaataaag
      721 attggttctc ttttctaagt tttcatagta ctcattattc actgattcaa gaccatgttc
      781 attgaggact
//
LOCUS       DAIGTA010000186          790 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.199, whole genome shotgun sequence.
ACCESSION   DAIGTA010000186 DAIGTA010000000
VERSION     DAIGTA010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.199"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            123..>790
                     /locus_tag="NOB43_002865"
     CDS             123..>790
                     /locus_tag="NOB43_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0983641.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEV"
BASE COUNT          285 a          124 c          143 g          238 t
ORIGIN      
        1 ttttacactc tcataaaaga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
       61 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      121 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      181 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      241 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      301 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      361 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      421 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      481 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      541 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      601 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
      661 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
      721 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
      781 aagaagtttt
//
LOCUS       DAIGTA010000187          790 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.200, whole genome shotgun sequence.
ACCESSION   DAIGTA010000187 DAIGTA010000000
VERSION     DAIGTA010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.200"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..506
                     /locus_tag="NOB43_002866"
     CDS             <1..506
                     /locus_tag="NOB43_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983642.1"
                     /translation="LLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGR
                     KEICEDFKLVYQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRR
                     TIYSTNLIEGFNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQ
                     DTLESMI"
BASE COUNT          278 a          131 c          115 g          266 t
ORIGIN      
        1 ttttattagt agtgacagac ggattaagct gtattgaaga aagtatccat agtgtgtatc
       61 cgaatgccca atttcaacaa tgttgtgtgc atgtatctag aaatatcgct cataaagttc
      121 gtgttcgagg tcgaaaagaa atttgtgagg atttcaaatt ggtttaccaa gcgaattcaa
      181 aagaagaggc attggatcac atcgacttta tgactaggaa atggaaaaag cagtatccaa
      241 gagtcgtcaa tttactcttg aatcctgccc tattaacctt ttataatttc cctcacgcca
      301 tcagacgaac aatttattcg acgaacctga ttgaaggctt taataagcag ctaaaacgat
      361 atactcgaag aaaagaacaa ttccctaatg aagaatctct agagagattc ttcatttctc
      421 aatttaatca atataaccaa aaatttttag gtagaattca caagggattt aaagaaattc
      481 aggatacatt agagtcgatg atttaactgt aattaacaga atggattttc catttacata
      541 taattcttga cgctaccata atctaaataa ccatcatatt catctactac ttatataatt
      601 gagttttatt aaacttttta agtttctatt ctatcaaata tttaaacaat ctctgcatcc
      661 gaaaagacta cctcgtatag ttttactaac aatattttta ttagcgtgtt caaatcctga
      721 tttcttgtat caattatttt ctgttcactt tcaataagaa aaaagtcttt acttccatgg
      781 ataataataa
//
LOCUS       DAIGTA010000188          787 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.201, whole genome shotgun sequence.
ACCESSION   DAIGTA010000188 DAIGTA010000000
VERSION     DAIGTA010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.201"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..447
                     /locus_tag="NOB43_002867"
     CDS             <1..447
                     /locus_tag="NOB43_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI0983643.1"
                     /translation="EIKLKEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGI
                     HCFNRGKNFTYELIHKKKKVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARA
                     SIRETAEEVRREQRTLTPEQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            407..685
                     /locus_tag="NOB43_002868"
     CDS             407..685
                     /locus_tag="NOB43_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983644.1"
                     /translation="MKEEQTTNKNYRSKTLKDIENEIKKQRAFLVPYTQERIQTTIDL
                     QVKKLHQELLDQRNKEQKKVLIQRSLDFLAPLCCLVLTLFAFWLVWGG"
BASE COUNT          309 a          151 c          144 g          183 t
ORIGIN      
        1 gaaataaaat taaaagaaaa aaatgaacct gtttggaaag acgaaattcg gattgcgatc
       61 gatcaaacaa tgaaaaacaa aaaaaccaga acctatgacc aattttgtaa ttccctcaaa
      121 acattgggga ttcattgctt caatcgcggg aaaaatttca cttacgaatt gatccacaaa
      181 aagaaaaaag tacgatccaa cagactagga aaggactacg aaaaggagac gattttacat
      241 gagctggaca gacgagaacg aacctataac caacagcgaa ccaacgagct acgaagagct
      301 cgagctagca ttcgcgaaac tgcagaagaa gtacgaagag aacaacgaac tcttacgcct
      361 gaacaaccgg aaattagacc ggctcgaaga aaccatgaac aacacgttga aagaggaaca
      421 gaccaccaac aagaattatc gctctaaaac gttaaaagac atagaaaacg aaataaagaa
      481 acaacgtgct tttctcgttc cttatacgca agaaaggata caaactacga ttgatttaca
      541 agttaaaaaa ctccatcaag agctattaga ccagcgaaat aaggaacaga aaaaggtgct
      601 tattcaacga tcattggatt ttcttgcccc cttatgttgc ttagtcctga cactgttcgc
      661 attttggtta gtatggggag gctaaaatgg cattttattt accctatcta ctcatttttg
      721 ttagtatttc aggaagtatt tggctcatct ataaaatttt tcaaacaaga tattcattaa
      781 aaggctc
//
LOCUS       DAIGTA010000189          731 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.202, whole genome shotgun sequence.
ACCESSION   DAIGTA010000189 DAIGTA010000000
VERSION     DAIGTA010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.202"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="NOB43_002869"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="NOB43_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HCI0983645.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(481..675)
                     /locus_tag="NOB43_002870"
     CDS             complement(481..675)
                     /locus_tag="NOB43_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983646.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          220 a          156 c          122 g          233 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc
      661 atttaattta tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg
      721 catttgttag t
//
LOCUS       DAIGTA010000190          723 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.203, whole genome shotgun sequence.
ACCESSION   DAIGTA010000190 DAIGTA010000000
VERSION     DAIGTA010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.203"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            15..>723
                     /locus_tag="NOB43_002871"
     CDS             15..>723
                     /locus_tag="NOB43_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0983647.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT          253 a          126 c          138 g          206 t
ORIGIN      
        1 aggagtgagt acaaatgacc tatacccatc ttacaacgga tgaacttgta ataatagagt
       61 cttatttcaa aatgaatcaa tctgttgcta aaactgccca ttgcttgaat cgttcaagac
      121 aaacgatcca taaagtatat ctgttcttca agcaaggaaa atcagcctta gaatattatc
      181 aacagtataa gaaaaacaaa tcaaactgtg gtagacgtcc gcttgtttta cccgaggaac
      241 aatcagaata tattcaaaga aaggttgttc aaggatggac acccgatgtg attgttggtc
      301 gtgcagcgtt tcctattagt tgttctgctc gtaccattta tcgtatgttc aaaaaggggc
      361 tatttgattc ttctgactta ccgatgaaag gcaagcgtaa accgaatgga catcaagaaa
      421 gacgtggaaa acaaactttc cgccgctcta ttcatgaacg tgaaaaggat tatagccaat
      481 tctcaaatga gtttggtcac cttgaaggtg acactatcgt aggtctgaaa cataaaagtg
      541 ctgtaattac cttagttgaa cgattatcaa aagttatcat cacattgaaa ccgtgtggta
      601 gacaagcgat tgatattgaa aaaaaattaa atcaatggtt tgaatctgta ccgaaaaacc
      661 tattcaaatc catcactttt gattgtggaa aggaattttc aaattggaaa cagatcagta
      721 atg
//
LOCUS       DAIGTA010000191          705 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.204, whole genome shotgun sequence.
ACCESSION   DAIGTA010000191 DAIGTA010000000
VERSION     DAIGTA010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.204"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            576..>705
                     /locus_tag="NOB43_002872"
     CDS             576..>705
                     /locus_tag="NOB43_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983648.1"
                     /translation="MSRRQRRTYSKEFKQQIVDLYLAGKPRAEIIREYELTPSSFDK"
BASE COUNT          254 a          125 c          104 g          222 t
ORIGIN      
        1 gtcaaaaaag aggacgaata caggtagtcc tcttttttgt tattttgata ttctaaatca
       61 ttttttattg gattattccc ttattcgatg tagactcaaa tcactatatc actagatatc
      121 aaacggcgtc atacggaatc aaaaacatca aatttgacct gttaaatggt cattgaataa
      181 catttaaaat caataaaacg gagtcagaca cggagtcaaa aacgctgaga gtaaaaaata
      241 tatacagcct tgtaggtaaa gtaccacagg gctgtatatt ttttatttca gattacctta
      301 aatgattcca tttacttttt atctcatttt ttcctactag ttagtatcaa atactcgcct
      361 attttctcaa taaactattt ttggttacat ggtatctgaa acagctaaaa ccttgtcatt
      421 atagcaaaaa atcactttat ctccgtttca tttcagatac atttcactta agcggattcc
      481 aaaaaaacaa aagaaaaagg atgaatcggc tacactagac tagacagaaa aaataaggtg
      541 tgtagaataa taaaaaacac actggaggat ttttcatgtc aagacgtcaa cgaagaactt
      601 attcaaaaga attcaaacaa caaatcgtcg atctctatct cgctggtaag cctcgcgcag
      661 aaattattcg agagtatgag cttacgcctt cttctttcga taaat
//
LOCUS       DAIGTA010000192          693 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.205, whole genome shotgun sequence.
ACCESSION   DAIGTA010000192 DAIGTA010000000
VERSION     DAIGTA010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.205"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(50..625)
                     /locus_tag="NOB43_002873"
     CDS             complement(50..625)
                     /locus_tag="NOB43_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0983649.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          228 a          151 c          124 g          190 t
ORIGIN      
        1 aaaaaacaga gccagattag cattattttg ctaatccagc tctgtttatt cagcctattt
       61 ttctttttga atatatcaag cgttggggca acatagtgat gactaatgaa acaacgacga
      121 tagacaacaa gcgatcaagg tagtctgtac ccgcctgtac caagatcaca cttgttgtct
      181 gacttaaacc taacccatgt aatagctgaa cgatcatact ggatcctgag gaggtgatcc
      241 cgccaaataa ctgaacggta atgatcgaag aaacgatcgt tccaggtacc gacaaaatca
      301 aagcgagtaa taacagtttc aagctgtttt tatctttgcc gagatatctt ggcaaaatca
      361 atccagcaag caagcctgtg agaatttgga ttggcgaata atacagagaa aaaatatctg
      421 tagtcactcc acttaaaata ccgctggaca atcctgtcag cattccaggt acaggcccaa
      481 gcaatgcacc agcaaaaatc gttccgatag aatcgagata gattggcaaa cgaagccata
      541 aagcaatcgt tcctccaata taattgatcc caatacacaa agccatcact gtaagtacgc
      601 gagttgccat tttgttttta ttcattttgt tagcccatct ttaacctttc caaatctttc
      661 ataatcgttt cttcttgtgc atttaaaaga acg
//
LOCUS       DAIGTA010000193          685 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.206, whole genome shotgun sequence.
ACCESSION   DAIGTA010000193 DAIGTA010000000
VERSION     DAIGTA010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.206"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            42..>685
                     /locus_tag="NOB43_002874"
     CDS             42..>685
                     /locus_tag="NOB43_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001878362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein"
                     /protein_id="HCI0983650.1"
                     /translation="MCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRR
                     FQNCSLYPVYHGSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRL
                     AYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKL
                     NSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQY"
BASE COUNT          250 a          106 c          145 g          184 t
ORIGIN      
        1 tggaaattat aatcaaacag aaagtagagc tgcaccctaa tatgtgtgtg atgagctgta
       61 cggaacctga gcaatgggat gtggtaatag aaggaaatga tgacctttta gagaaatata
      121 tgtccggtaa atcattagaa gcattagaac tcgaacaaga ggaaatcaga agatttcaga
      181 attgctcctt gtaccctgtt tatcatggaa gcgcaaaaag caacataggg attgagcagc
      241 ttatagaagt gataacgaat aaattttatt catcaacata cagaaagaag tctgaacttt
      301 gcggaaatgt cttcaaaatt gaatattcgg aagaaagaca acgtcttgca tatgtacgcc
      361 tttatggcgg aatcctgcat ttgcgggatt cggttagaat atcggaaaag gaaaaaataa
      421 aaattacaga aatgtatact tcaataaatg gtgaattatg taaaattgat aaggcttatt
      481 ccggggaaat tgttattttg caaaatgagt ttttgaagct aaatagtgtt cttggagata
      541 caaagctatt gccacagaga gagagaattg aaaatccgct ccctctgctg caaacaactg
      601 ttgaaccgag caaacctcaa caaagggaaa tgttacttga tgcactttta gaaatctccg
      661 acagtgaccc gcttctacaa tatta
//
LOCUS       DAIGTA010000194          637 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.207, whole genome shotgun sequence.
ACCESSION   DAIGTA010000194 DAIGTA010000000
VERSION     DAIGTA010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.207"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            51..>637
                     /locus_tag="NOB43_002875"
     CDS             51..>637
                     /locus_tag="NOB43_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HCI0983651.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEA"
BASE COUNT          231 a          106 c          126 g          174 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccacgatt aaaggcatgg aagccat
//
LOCUS       DAIGTA010000195          583 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.208, whole genome shotgun sequence.
ACCESSION   DAIGTA010000195 DAIGTA010000000
VERSION     DAIGTA010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.208"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..>583)
                     /locus_tag="NOB43_002876"
     CDS             complement(<1..>583)
                     /locus_tag="NOB43_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCI0983652.1"
                     /translation="VLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQIEKG
                     FGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGINTVL
                     ETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIEYPNC
                     EVRIRVPVVPGINMNLTELLTIACFVADLDRFVP"
BASE COUNT          168 a          145 c          106 g          164 t
ORIGIN      
        1 cggtacgaac cgatcaagat ctgccacaaa acaagcaatc gtcagcagct cggtcaggtt
       61 catattgata cctggaacca caggaactcg aattcgcact tcgcagttag gatactcaat
      121 taaaaagcga cgaatattct tcaaaatttg ttggttatct aagccggtcc attgtttgtg
      181 gagcttgctg gtaaacattt ttacatccac aaacaatgta tccacatagg gagctacctt
      241 ttggatttca ttataagcac cacaaaagct ggtttccagt acggtattga ttccaatgta
      301 tttcgatttt tgcaaaattt ctttagcaaa atccgcctga accagtgcct cgcctccgct
      361 aatggtcact ccgccatccg agtgaaagta aaaaacagca tccttctcaa tctcatccat
      421 tacctcttca gcggtcatgg tctggccaaa tcctttttca atctgcttgc tttgtgattc
      481 gggaatcgaa caccaggcac agcgtaatgg gcagcccttt aaataaacaa cggtccgtaa
      541 accagcacca tcatgtagag aaccctgttc tattcttaat act
//
LOCUS       DAIGTA010000196          579 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.209, whole genome shotgun sequence.
ACCESSION   DAIGTA010000196 DAIGTA010000000
VERSION     DAIGTA010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.209"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>579
                     /locus_tag="NOB43_002877"
     rRNA            <1..>579
                     /locus_tag="NOB43_002877"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          114 c          173 g          120 t
ORIGIN      
        1 aaagcacccc ggaaggggag tgaaatagaa cctgaaaccg tgtgcctaca acaagtcaaa
       61 gcccgttaat gggtgatggc gtgccttttg tagaatgaac cggcgagtta cgattgcatg
      121 cgaggttaag ttgaagagac ggagccgcag cgaaagcgag tctgaatagg gcgtttgagt
      181 atgtagtcgt agacccgaaa ccatgtgatc tacccatgtc caggttgaag gtgcggtaaa
      241 acgcactgga ggaccgaacc cacgtacgtt gaaaagtgcg gggatgaggt gtgggtagcg
      301 gagaaattcc aaacgaactt ggagatagct ggttctctcc gaaatagctt tagggctagc
      361 ctcggaattg agaatgatgg aggtagagca ctgtttggac taggggccca tctcgggtta
      421 ccgaattcag ataaactccg aatgccattc attcatatcc gggagtcaga ctgtgagtga
      481 taagatccat agtcgaaagg gaaacagccc agaccaccag ctaaggtccc aaaatatatg
      541 ttaagtggaa aaggatgtgg ggttgcacag acaactagg
//
LOCUS       DAIGTA010000197          568 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.210, whole genome shotgun sequence.
ACCESSION   DAIGTA010000197 DAIGTA010000000
VERSION     DAIGTA010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.210"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>568
                     /locus_tag="NOB43_002878"
     CDS             <1..>568
                     /locus_tag="NOB43_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0983653.1"
                     /translation="KGKGRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVRE
                     IRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKL
                     AKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYK
                     EVPKHQHKRALVLTARKFTRLVDTLLRKH"
BASE COUNT          212 a          109 c          103 g          144 t
ORIGIN      
        1 aaaggaaaag gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt
       61 accatgagtt accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt
      121 ctcgtacgag aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa
      181 caagtaattg ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa
      241 gtctatgctg ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca
      301 aaattggcaa aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg
      361 caaaatacac ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct
      421 gccaactctg taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag
      481 gaggttccaa agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt
      541 ctggtggata cgctactacg taaacacc
//
LOCUS       DAIGTA010000198          568 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.211, whole genome shotgun sequence.
ACCESSION   DAIGTA010000198 DAIGTA010000000
VERSION     DAIGTA010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.211"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            151..531
                     /locus_tag="NOB43_002879"
     CDS             151..531
                     /locus_tag="NOB43_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCI0983654.1"
                     /translation="MSEQNQNLASNYSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
BASE COUNT          184 a          119 c          129 g          136 t
ORIGIN      
        1 aagcggttat ttgcaccaaa tacggaggca tttggctagc aaatatagag cttgccaaac
       61 ccttttagtg agctttactc attgtacctt tttaggtaca atggtattgc gaacgatacg
      121 tccgtaggac gtactgaaag ggtgggactt atgagcgaac aaaatcaaaa tttggctagc
      181 aattattcta aaaaatatac ctatcgatcc gagccaaaac aaatcagttt tcgagtgagc
      241 gaatccgaat ttgcaaagct gaagcaatcg gctgaagctt tgcaaatgag tgtgccggct
      301 ttcgtgaaag ccaaggcaca aaacgcgcgt ctggtgacac cgaaagtggc gccagacatt
      361 gcccaggcaa tcgcgcgcga tttagccaaa gctggaggga atatcaatca aattgctaag
      421 tggtgcaata cacaccaaca tgacgttgct tctggtgacg ctcaacgttt atccgaaaac
      481 ctaaaaatca tgcaaaagga gctacaaaag atatggcaac aattaaggta agccgaacca
      541 cttcttgtag tcgtgcaatt aattatgc
//
LOCUS       DAIGTA010000199          568 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.212, whole genome shotgun sequence.
ACCESSION   DAIGTA010000199 DAIGTA010000000
VERSION     DAIGTA010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.212"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            151..531
                     /locus_tag="NOB43_002880"
     CDS             151..531
                     /locus_tag="NOB43_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCI0983655.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQLK"
BASE COUNT          185 a          122 c          128 g          133 t
ORIGIN      
        1 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaaac
       61 ccttttagtg agctttactc attgtacctt tttaggtaca atggtattgc gaacgatacg
      121 tccgtaggac gtactgaaag ggtgggactt atgagcgaac aaaatcaaaa tttggctagc
      181 gatcattcta aaaaatatac ctatcgatcc gagccaaaac aaatcagttt tcgagtgagc
      241 gaatctgaat ttgcaaagct gaagcagtca gctgaagctt tgcaaatgag tgtgccggct
      301 ttcgtaaaag ccaaggcaca aaacgcgcgt ctggtgacac cgaaagtggc gccagacatt
      361 gcccaggcaa tcgcgcgcga tttagccaaa gctggaggga atatcaatca aattgctaag
      421 tggtgtaata cacaccaaca cgacgttgct cctggagacg cccaacgctt atccgaaaac
      481 ctaaaaatca tgcaaaagga gctacaaaag atatggcaac agttaaagta agccgaacca
      541 cttcttgtag tcgtgcaatt aattacgc
//
LOCUS       DAIGTA010000200          564 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.213, whole genome shotgun sequence.
ACCESSION   DAIGTA010000200 DAIGTA010000000
VERSION     DAIGTA010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.213"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..233
                     /locus_tag="NOB43_002881"
     CDS             <1..233
                     /locus_tag="NOB43_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HCI0983656.1"
                     /translation="KGYQVVVTADHGMDAHGLHGGSLAAHREVPFYLISNKRQKLKEQ
                     TVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            230..>564
                     /locus_tag="NOB43_002882"
     CDS             230..>564
                     /locus_tag="NOB43_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983657.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLA"
BASE COUNT          145 a          109 c          134 g          176 t
ORIGIN      
        1 aaaaaggtta tcaagtcgtg gtgactgcgg atcacgggat ggatgcgcac ggactgcatg
       61 gcggcagctt ggctgcacat cgtgaagttc ctttttattt gatttcaaat aaacgccaaa
      121 agctgaagga acaaactgta ccacagctgc tggcggctcc attgttttgc tggttattag
      181 gaattgcacc gtcagagaaa atgcaggaca ttcaagaatt gatgagggga tgaaagagat
      241 gaaaaaacgc ttggttctgg ttcctgcctc ctttatcttc tgtgcatttt tactgctgcc
      301 gctgcttttt atggttctgt gcagcttgca cagtgattta actaaccagt ggacattggc
      361 caattacagt gatattttca gcaacaaata ttacacacag gcctttgtta acagcgtact
      421 gattgctgtc agctccagtg tgattgggtt aatcgggacg tttattttat gtttatgctt
      481 aatgaatcta tcgactaaat tgcaggagaa aatcaccttt gtttccaatt tggcagctaa
      541 ttttgctggg attccgctgg catt
//
LOCUS       DAIGTA010000201          561 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.214, whole genome shotgun sequence.
ACCESSION   DAIGTA010000201 DAIGTA010000000
VERSION     DAIGTA010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.214"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..528
                     /locus_tag="NOB43_002883"
     CDS             <1..528
                     /locus_tag="NOB43_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983658.1"
                     /translation="RTFRNHRIKETNQLLKSKEQKHYQLGKQLKRYWKLLQKDERKLD
                     YTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFLYAVKERDYVSFEELLTN
                     NIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHIKVLKRNAYGFRSFYNF
                     KLRIMIRHGNALIFN"
BASE COUNT          198 a          117 c           96 g          150 t
ORIGIN      
        1 cgtacctttc gcaatcatcg aatcaaagaa acgaaccaac tattaaaaag caaagaacaa
       61 aaacactatc aattaggtaa gcaattaaaa agatactgga aacttcttca aaaagatgaa
      121 cgcaagcttg attatactcg acgcctttgg cgacctggct tcaaagctca tttaacagag
      181 accgatattg tggatcgctt actgaaaggg agccctgctt tgcgtgtagg ctatcagtta
      241 tatcaagact ttctttacgc tgtaaaggaa cgagactacg tatcgtttga agaactactt
      301 accaataata tcatgcttcc cgaaggctat cagacgacct tgagaacgtt ccagaaattt
      361 ctgccacaaa tcaaaaatgc tttacaacaa agttattcaa atggcccact tgaatgtctg
      421 aacaaccata tcaaagtgtt aaaacgaaat gcatatggct ttcgtagctt ttataatttc
      481 aaattgcgca tcatgattcg tcatggcaac gcattgattt tcaactaaaa aagatcaaga
      541 ggaactgatc cacttgatct c
//
LOCUS       DAIGTA010000202          528 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.215, whole genome shotgun sequence.
ACCESSION   DAIGTA010000202 DAIGTA010000000
VERSION     DAIGTA010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.215"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(5..90)
                     /locus_tag="NOB43_002884"
     tRNA            complement(5..90)
                     /locus_tag="NOB43_002884"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="NOB43_002885"
     tRNA            complement(107..178)
                     /locus_tag="NOB43_002885"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="NOB43_002886"
     tRNA            complement(190..262)
                     /locus_tag="NOB43_002886"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="NOB43_002887"
     tRNA            complement(280..361)
                     /locus_tag="NOB43_002887"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="NOB43_002888"
     tRNA            complement(369..441)
                     /locus_tag="NOB43_002888"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="NOB43_002889"
     tRNA            complement(445..517)
                     /locus_tag="NOB43_002889"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAIGTA010000203          510 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.216, whole genome shotgun sequence.
ACCESSION   DAIGTA010000203 DAIGTA010000000
VERSION     DAIGTA010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.216"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..434)
                     /locus_tag="NOB43_002890"
     CDS             complement(<1..434)
                     /locus_tag="NOB43_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983659.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
BASE COUNT          146 a           85 c           80 g          199 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc
//
LOCUS       DAIGTA010000204          509 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.217, whole genome shotgun sequence.
ACCESSION   DAIGTA010000204 DAIGTA010000000
VERSION     DAIGTA010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.217"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
BASE COUNT          228 a           70 c           81 g          130 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactct
//
LOCUS       DAIGTA010000205          508 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.218, whole genome shotgun sequence.
ACCESSION   DAIGTA010000205 DAIGTA010000000
VERSION     DAIGTA010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.218"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(77..149)
                     /locus_tag="NOB43_002891"
     tRNA            complement(77..149)
                     /locus_tag="NOB43_002891"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
BASE COUNT          162 a          112 c           83 g          151 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaa
//
LOCUS       DAIGTA010000206          480 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.219, whole genome shotgun sequence.
ACCESSION   DAIGTA010000206 DAIGTA010000000
VERSION     DAIGTA010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.219"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            6..398
                     /locus_tag="NOB43_002892"
     CDS             6..398
                     /locus_tag="NOB43_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0983660.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
BASE COUNT          187 a           34 c           83 g          176 t
ORIGIN      
        1 agtttatgga agaagtttta attgatgata atatggtttt tgatattgat aatttaaaag
       61 gatttcttaa tgataccagt tcatttgggt ttatagctaa agaaaataat aaaattatag
      121 gatttgcata ttgctataca cttttaagac ctgatggaaa aacaatgttt tatttacact
      181 caataggaat gttacctaac tatcaagaca aaggttatgg ttcaaaatta ttatctttta
      241 ttaaggaata ttctaaagag attggttgtt ctgaaatgtt tttaataact gataaaggta
      301 atcctagagc ttgccatgta tatgaaaaat taggtggtaa aaatgattat aaagatgaaa
      361 tagtatatgt atatgattat gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa
      421 tatgtataag aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg
//
LOCUS       DAIGTA010000207          479 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.220, whole genome shotgun sequence.
ACCESSION   DAIGTA010000207 DAIGTA010000000
VERSION     DAIGTA010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.220"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            136..>479
                     /locus_tag="NOB43_002893"
     CDS             136..>479
                     /locus_tag="NOB43_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983661.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQ"
BASE COUNT          214 a           65 c           69 g          131 t
ORIGIN      
        1 aacatttaca aaattagcta aagctgaaca atatagacga tctttagaat tgtcaaaaga
       61 ttaaatatat aaaaagcctt cgggcttttt cttttaacaa ttaataggaa cgtatattcg
      121 aaaggaatag aaataatgtg gttagaaaaa ataaatgaca aaaaatttaa gtacaccgaa
      181 cgttatacgg atcccttaac tgaaaaaaag agaaaagtgt ccgttacttt atctagcaat
      241 tcacgccaag cttggaatca agctaactta cttttgaatg aaaaaatcgc agaaaaaata
      301 aaacgaaatg aagaattacc actaactttt ggagaattaa aaactaaatg ggatgaaaaa
      361 tacaagccaa ctgtaaaaga aagttcctat cgaacaactc aggtttatct atcattaatt
      421 tcaaaatata taaaagatga tgtacttgta aaaaacgtta atagtaatct tatacaaga
//
LOCUS       DAIGTA010000208          474 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.221, whole genome shotgun sequence.
ACCESSION   DAIGTA010000208 DAIGTA010000000
VERSION     DAIGTA010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.221"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
BASE COUNT          199 a           77 c           67 g          131 t
ORIGIN      
        1 tattaaaaac caagcaatcc ttgattggga tgaaagaact ccattaaaac ttgtaaatgt
       61 tattaaatat taatttataa gcaaataaac caaaagagac tgggccaaaa aattgacggc
      121 tctataattt atgggactga agaatcaaaa ttgattcttc agccccattt tcatttttgc
      181 tattaaaaaa catatcgttc tctagtatga ttaaatcacc aaaacctaac caactgagag
      241 gacgatatgc tctatgaacg attctatcaa aaagatggcg agattagtaa ataaaatata
      301 gagaaattaa aataacaaaa aatgagacag aatgagcttc actctgaccc aaattggatt
      361 ttacacaact tatcagtcct tattgacaaa gagcccttaa aaatacaaat aaaaaaagct
      421 cgaaacgctt taatataaac gtttcgagca atgaattagt tgttatccaa caga
//
LOCUS       DAIGTA010000209          472 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.222, whole genome shotgun sequence.
ACCESSION   DAIGTA010000209 DAIGTA010000000
VERSION     DAIGTA010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.222"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>472
                     /locus_tag="NOB43_002894"
     CDS             <1..>472
                     /locus_tag="NOB43_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983662.1"
                     /translation="LSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLN
                     KLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIK
                     VDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH"
BASE COUNT          174 a           68 c           88 g          142 t
ORIGIN      
        1 ttgtctaggc gtgctttatt ggctaaaaat aaaggtacca atctatttga agctaaaaat
       61 tatcaaaaac aaaaacgcaa agtagctaga ttgcatgaaa aagtaatgaa tcaacgtact
      121 gattttctga ataagttgag tacagaaatg atcaaaaatc acgatattat ctgtattgaa
      181 gacttaaaca caaaaggtat gttgcgaaat cataaattag ctaaaagtat ttctgatgtt
      241 tcttggtcaa agtttgtgac taaattacaa tacaaggctg actggtatgg acgaaaaatc
      301 atcaaagtag ataaatggtt tccgtctagt cagatttgtt cagagtgcgg acataaagat
      361 ggcaagaaat ctcttgaaat tcgagaatgg acttgtcctg tttgtcatac tcatcatgat
      421 cgtgatatca atgctagtat caatattctg accgaaggtc taagactaca tt
//
LOCUS       DAIGTA010000210          465 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.223, whole genome shotgun sequence.
ACCESSION   DAIGTA010000210 DAIGTA010000000
VERSION     DAIGTA010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.223"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            105..434
                     /locus_tag="NOB43_002895"
     CDS             105..434
                     /locus_tag="NOB43_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0983663.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          179 a           56 c           85 g          145 t
ORIGIN      
        1 agcaaggacg cattacgagt cacagtaatt acttgtaaat acattatctc gtggtataat
       61 gtatttacta agtaattaca tactgttaga aatgagggat ttaaatgatt acaaaaacaa
      121 gaaaacaagg caattcaatc atgttgacag tacctaaaga ttttaatgtt cctaatggag
      181 tcgaagttga agcaaagttg gtagagaatg gtattcttta tgaatttgtt gaaccacaaa
      241 aagaatttta tgattttagc gaagatattt tgtctgatat aattgcagaa ggctacgata
      301 aagatgagat tcttgtagaa tttaagaata gaaaaaacaa aatgcattct tcctttagag
      361 atattgctga agatacactt actaattcta aagtaatgac taaagaggag ttggcaacag
      421 aaattggctt atgaaatcgt tccttcaaaa catgtcatta agtat
//
LOCUS       DAIGTA010000211          463 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.224, whole genome shotgun sequence.
ACCESSION   DAIGTA010000211 DAIGTA010000000
VERSION     DAIGTA010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.224"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            1..>463
                     /locus_tag="NOB43_002896"
     rRNA            1..>463
                     /locus_tag="NOB43_002896"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          147 a           92 c          131 g           93 t
ORIGIN      
        1 ataagggcgc acggtggatg ccttggcact aggagccgat gaaggacggg actaacaccg
       61 atatgctttg gggagctgta cgtaagctat gatccagaga tttccgaatg ggggaaccca
      121 acatctttaa taggatgtta cgattgtgtg aatacatagc acattcgagg tagacgcaga
      181 gaactgaaac atctaagtac ctgcaggaag agaaagaaaa ttcgattccc tgagtagcgg
      241 cgagcgaaac gggaaaagcc caaaccagca agcttgcttg ttggggttgt aggactccaa
      301 tatggtagtt ctttcagata gtcgaatgac ttggaaaagt cagtcaaaga gggtaaaaac
      361 cccgtagacg aaatgtggaa gacacctagg aggatcctga gtacggcgga acacgagaaa
      421 ttccgtcgga atccgggagg accatctccc aaggctaaat act
//
LOCUS       DAIGTA010000212          463 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.225, whole genome shotgun sequence.
ACCESSION   DAIGTA010000212 DAIGTA010000000
VERSION     DAIGTA010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.225"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(156..404)
                     /locus_tag="NOB43_002897"
     CDS             complement(156..404)
                     /locus_tag="NOB43_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005225422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0983664.1"
                     /translation="MHWLWVLIVGAIIGLIAGAITNKGGSMGWIANIVAGLVGSAIGQ
                     ALLGSWGPQLAGMALIPSIIGAIIVVAVVSFFLGRSRG"
BASE COUNT          157 a          101 c           68 g          137 t
ORIGIN      
        1 tattttttaa tctgacaaag gtaatgcttg cattcggcga catcagttag acaacatcga
       61 tgatcagtga tagaagcagt ttatctatac aaaaaaagaa gcagcgaaaa tctgctcctt
      121 aagataatag gtaaaattgc tgatatattt gacgattaac ctcttgaacg tcccaagaaa
      181 aatgatacta cagcaacaac gatgatcgca ccaatgatag aaggaatcaa agccattcct
      241 gctaattgag gaccccagct acctaacaat gcttgtccaa ttgctgaacc aactaaacct
      301 gcaacgatgt tagctatcca tcccattgat ccacctttat ttgtaattgc tccggcaatc
      361 aaaccgataa tagctcctac gattaatacc cataaccaat gcataatttt ctctttcttt
      421 ctgtgaaata tttattacac atattatgtt acgcttcttc tta
//
LOCUS       DAIGTA010000213          460 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.226, whole genome shotgun sequence.
ACCESSION   DAIGTA010000213 DAIGTA010000000
VERSION     DAIGTA010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.226"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(20..91)
                     /locus_tag="NOB43_002898"
     tRNA            complement(20..91)
                     /locus_tag="NOB43_002898"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="NOB43_002899"
     tRNA            complement(113..200)
                     /locus_tag="NOB43_002899"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="NOB43_002900"
     tRNA            complement(225..298)
                     /locus_tag="NOB43_002900"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="NOB43_002901"
     tRNA            complement(312..382)
                     /locus_tag="NOB43_002901"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="NOB43_002902"
     tRNA            complement(384..459)
                     /locus_tag="NOB43_002902"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAIGTA010000214          456 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.227, whole genome shotgun sequence.
ACCESSION   DAIGTA010000214 DAIGTA010000000
VERSION     DAIGTA010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.227"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..426)
                     /locus_tag="NOB43_002903"
     CDS             complement(<1..426)
                     /locus_tag="NOB43_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0983665.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQ"
BASE COUNT          132 a           96 c           68 g          160 t
ORIGIN      
        1 ctgataaacc gttgataaat caattccatt ttggtcaatc ttattgataa aaaagattgt
       61 gggaatcccc attttcctaa gtgcatgaaa taatatacga gtttgtgctt gtacgccatc
      121 ttttgcagaa atcagtagaa ttgccccatc taaaactgat aatgaacgat atacttctgc
      181 taagaaatcc atatgtcctg gcgtgtctat gatgttcacc ttcgtatttt cccactgaaa
      241 agaggttatt cctgtctgaa ttgtaattcc tctctgacgt tctaaaagcg tattatccgt
      301 cctcgttgta cctttgtcca cgcttcctaa ttctgtaatc gctccactgt tatataataa
      361 gctttctgtt aaggtagttt ttcctgcatc aacatgagct aaaactccaa tattaataat
      421 tttcatgtga ttttcctcca ttcaaaaacc caaaag
//
LOCUS       DAIGTA010000215          450 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.228, whole genome shotgun sequence.
ACCESSION   DAIGTA010000215 DAIGTA010000000
VERSION     DAIGTA010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.228"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
BASE COUNT          143 a           90 c           67 g          150 t
ORIGIN      
        1 acactcctct taatatacag tcctattgta taaagtgtta ctatatacat agtaactgta
       61 tacataaaaa aagtcaagta ttagaaaaaa gttcaaaaga tcaagtgtgc gcttcgctcc
      121 cactcccctc gacgttttag tagcctttcc ctcacttcgt tcagtccaag ccaactaaaa
      181 agttttcggg atacattctc cttctcttcc taataatcaa ttaaaatttt aatctttata
      241 tttctgctaa tcactcagga aacagtacag aaaaacaaac acgtatcata gatataaatg
      301 taatggcata gtgcgggttt tattttcagc ctgtatcata gctaaacaaa tcgagttgtg
      361 tgtccgtttt tgggcgttct gctagcttgt ttaaagtctc ttgaatgaat gtatgttcta
      421 agtcaaaaaa ctctgacagc gcctttatat
//
LOCUS       DAIGTA010000216          427 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.229, whole genome shotgun sequence.
ACCESSION   DAIGTA010000216 DAIGTA010000000
VERSION     DAIGTA010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.229"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..>427)
                     /locus_tag="NOB43_002904"
     CDS             complement(<1..>427)
                     /locus_tag="NOB43_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983666.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDEL"
BASE COUNT          125 a           76 c           87 g          139 t
ORIGIN      
        1 agttcatcca atgtgaaatc ttccgtcatg agtgaaatga gggttgcact aaaaagactc
       61 gtcgattcgt ctcgcatttc tcgagcaagc gtattacatt tgtacgttag attttcaaga
      121 aaatgttgct ttgtacgaat caattgctta ataagttgat agcgagtacg tgttaaacgc
      181 tgtaaggcca tgtatttctc ttctttgata ggggaagttg tgaatcgttg aatacgcaag
      241 aaatcagcga ttcttaatgc atcgtttcga tcagttttat tctcatcaaa catgcgacta
      301 aattgtttca cccgaaaagg attttcaatc gttacaagtg tgttgagctt ctttagtttc
      361 tcatcttcat gaaaaaacat ggaaggatgg aagctgtaca tggacgttga ctccatgcca
      421 atcacaa
//
LOCUS       DAIGTA010000217          408 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.230, whole genome shotgun sequence.
ACCESSION   DAIGTA010000217 DAIGTA010000000
VERSION     DAIGTA010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.230"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..>408)
                     /locus_tag="NOB43_002905"
     CDS             complement(<1..>408)
                     /locus_tag="NOB43_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0983667.1"
                     /translation="ILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMKEVKKEWL
                     ESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSNVNLLTIR
                     IAALVSGDVFAKPNLGSALAVALGVLLVTAMLII"
BASE COUNT          134 a          104 c           82 g           88 t
ORIGIN      
        1 aataatcaac attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa
       61 attaggcttg gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt
      121 tacattactg ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa
      181 gatgacaaag gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc
      241 atacgctgat gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt
      301 catgctggga tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt
      361 caatccccac caagaataca aattgaagtc cgctagaaat ggcaaaat
//
LOCUS       DAIGTA010000218          404 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.231, whole genome shotgun sequence.
ACCESSION   DAIGTA010000218 DAIGTA010000000
VERSION     DAIGTA010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.231"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>404
                     /locus_tag="NOB43_002906"
     CDS             <1..>404
                     /locus_tag="NOB43_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983668.1"
                     /translation="PEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDK
                     SDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVV
                     VTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          166 a           60 c           92 g           86 t
ORIGIN      
        1 ccagaagata aacttccagt gttgaaagca aaagatggtt atacagatgc gaaatggcca
       61 gaggaagcaa ctcaaccaat tacagcagat gatacagaat ttgtatcaag tgcaacaaaa
      121 ctggatgata aatctgacgc tgacaaatat aatcctgaag gtcaaaaagt gactacagaa
      181 ttgaataagg aaccagacgc atttgaggga attaagaaca aagaagattt accaaaagat
      241 actaagtata cttggaaaga aaaagtagat gttagcgcag ctggaaataa aaaagggact
      301 gttgtagtga catatccaga tggatcatct gatgaagttg aagtagatgt tacagtgaca
      361 gacaatcgtt ctgacgccga taaatatgag ccaacagtag aagg
//
LOCUS       DAIGTA010000219          398 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.232, whole genome shotgun sequence.
ACCESSION   DAIGTA010000219 DAIGTA010000000
VERSION     DAIGTA010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.232"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>398
                     /locus_tag="NOB43_002907"
     CDS             <1..>398
                     /locus_tag="NOB43_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983669.1"
                     /translation="INTLLRTELTAFLDYEKYDRTGFNSGNSRNGSYFRSIKTEYGEL
                     TLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVTMSEIADLIEKMYGHHYTP
                     QTMSNMTKVLTEEVNAFKSRALNDKYVAIF"
BASE COUNT          145 a           73 c           65 g          115 t
ORIGIN      
        1 cgataaacac actcctacgg actgaattaa cggctttttt agattacgaa aaatatgatc
       61 gcactggttt taattcaggt aattcgagaa acggttctta ctttcgatca atcaaaaccg
      121 aatatggtga attaacattg gaaataccta gagatcgtaa tggtgagttt aaacaacaaa
      181 ctttaccagc ctacaaaaga acaaacgata cattggaaac cactattatc catttattcg
      241 aaaaaggtgt tacgatgtct gaaattgctg atttgatcga aaaaatgtac ggtcatcact
      301 atactccaca aaccatgtcc aacatgacta aagttctgac tgaagaagta aatgccttta
      361 aatccagagc cttaaatgat aagtatgtcg ctattttt
//
LOCUS       DAIGTA010000220          381 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.233, whole genome shotgun sequence.
ACCESSION   DAIGTA010000220 DAIGTA010000000
VERSION     DAIGTA010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.233"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(21..94)
                     /locus_tag="NOB43_002908"
     tRNA            complement(21..94)
                     /locus_tag="NOB43_002908"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="NOB43_002909"
     tRNA            complement(108..181)
                     /locus_tag="NOB43_002909"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="NOB43_002910"
     tRNA            complement(209..281)
                     /locus_tag="NOB43_002910"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="NOB43_002911"
     tRNA            complement(301..374)
                     /locus_tag="NOB43_002911"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
BASE COUNT          103 a          108 c           90 g           80 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat t
//
LOCUS       DAIGTA010000221          379 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.234, whole genome shotgun sequence.
ACCESSION   DAIGTA010000221 DAIGTA010000000
VERSION     DAIGTA010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.234"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..350
                     /locus_tag="NOB43_002912"
     CDS             <1..350
                     /locus_tag="NOB43_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983670.1"
                     /translation="EAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFE
                     DAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDE
                     WIYSSRKYINFDK"
BASE COUNT          141 a           66 c           66 g          106 t
ORIGIN      
        1 gagaagctgt taaaggaatt tttaagttca cagatattaa cttagcgcgt gaggctaaaa
       61 atcgattgat tcatgattat atcgatcaac caaaatattc aaaagcttgc gcatcattgg
      121 atgatggatt cgaagacgcc tttcaatata ccgtacaagg aaattcccac aatcgactaa
      181 agagtaccaa tctaattgaa cgactgaatc aagaagtacg cagaagagaa aagattattc
      241 gcatcttccc caatcaaaca tcagccaatc gcttaattgg agccgttctt atggacctac
      301 atgatgaatg gatttattct tcaagaaaat acatcaattt tgataagtag aaatggtaaa
      361 aacattgtat agcatttta
//
LOCUS       DAIGTA010000222          375 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.235, whole genome shotgun sequence.
ACCESSION   DAIGTA010000222 DAIGTA010000000
VERSION     DAIGTA010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.235"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..132)
                     /locus_tag="NOB43_002913"
     CDS             complement(<1..132)
                     /locus_tag="NOB43_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0983671.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DAIGTA010000223          347 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.236, whole genome shotgun sequence.
ACCESSION   DAIGTA010000223 DAIGTA010000000
VERSION     DAIGTA010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.236"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>347
                     /locus_tag="NOB43_002914"
     CDS             <1..>347
                     /locus_tag="NOB43_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI0983672.1"
                     /translation="TGINCDVDYAKSEMKQIRMLYGKDDRVQAHLLIQSFRPGEITAE
                     KANQLGAEYAKKIAPDHQIAIYTHTDKDHIHNHIVINSVNLETGKKFQAHGQAFLNKC
                     YDLNDEICLAHNLP"
BASE COUNT          132 a           71 c           59 g           85 t
ORIGIN      
        1 acaggaataa actgtgacgt cgattatgcc aaaagtgaaa tgaaacaaat tcgcatgctg
       61 tatggaaaag acgaccgtgt acaggcacac ttattgattc aatcttttcg accaggagaa
      121 attaccgctg aaaaagctaa tcaactaggg gcagagtatg caaaaaaaat agcccccgat
      181 caccaaatag ctatttacac acatacagac aaagaccata ttcataatca cattgtcatt
      241 aactccgtta atctggagac tggaaaaaaa tttcaagctc atggtcaagc atttctaaac
      301 aaatgttatg acctaaatga cgagatttgt cttgcacata acttacc
//
LOCUS       DAIGTA010000224          343 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.237, whole genome shotgun sequence.
ACCESSION   DAIGTA010000224 DAIGTA010000000
VERSION     DAIGTA010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.237"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>343
                     /locus_tag="NOB43_002915"
     CDS             <1..>343
                     /locus_tag="NOB43_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983673.1"
                     /translation="NMTKVLTEEVNAFKVRTLNDKYVAIFMDATYIPLKRQTVSKEAI
                     YIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRGVHDVLLFITDGLKGMKDTI
                     HQIYPKAKYQHC"
BASE COUNT          115 a           62 c           66 g          100 t
ORIGIN      
        1 aacatgacta aagtgctgac tgaagaagta aatgcattta aagttagaac tctaaatgat
       61 aagtatgtcg ctattttcat ggatgctact tatattcctt taaaacggca aaccgtctcc
      121 aaagaagcaa tctatattgc cattggtata cgagaagacg gcactaaaga agtactaagt
      181 tatgcgattg ctccgactga atcgacctac gtttggaatg agttgttaca ggacatttac
      241 tccagagggg ttcatgatgt cttactgttt attaccgatg gcttaaaagg catgaaagat
      301 acgattcacc agatttatcc taaagctaaa taccaacatt gct
//
LOCUS       DAIGTA010000225          342 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.238, whole genome shotgun sequence.
ACCESSION   DAIGTA010000225 DAIGTA010000000
VERSION     DAIGTA010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.238"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>342
                     /locus_tag="NOB43_002916"
     CDS             <1..>342
                     /locus_tag="NOB43_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983674.1"
                     /translation="ICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQD
                     LLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQK
                     FLNRSHKGFQQV"
BASE COUNT          132 a           64 c           52 g           94 t
ORIGIN      
        1 aatctgtgat gactttaagg ctgtttatca agctaactca aaagaagaag cgaatacctt
       61 cttatccggc atgattgaga aatggaagaa aaactatcct aaagtgacgc agtcactcat
      121 agaaaaccaa gacttattaa ctttttatga ttttccacct agcattcgta gaaccattta
      181 ctcaaccaat ctaatcgagt ctttcaataa gcaaattaaa agatacagcc gtagaaaaga
      241 gcagtttcaa aatgaagaat cactagaacg ctttctagtc agcatttttg atacatacaa
      301 tcaaaaattt ctaaacagaa gccataaagg ttttcaacag gt
//
LOCUS       DAIGTA010000226          340 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.239, whole genome shotgun sequence.
ACCESSION   DAIGTA010000226 DAIGTA010000000
VERSION     DAIGTA010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.239"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(63..>340)
                     /locus_tag="NOB43_002917"
     CDS             complement(63..>340)
                     /locus_tag="NOB43_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983675.1"
                     /translation="AKGNRCIYYLRPELIQFEPVPQGVKIPVLWKESFILGNIQRYVF
                     QTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEIDTQHFAQQS"
BASE COUNT           99 a           79 c           58 g          104 t
ORIGIN      
        1 gttcttatat cactctatca gtcctatttg acaaagagcc agaaatgttt gccgactata
       61 cactagcttt gttgtgcaaa atgctgagta tcaatttcca cagggattgc tagaatatct
      121 ttcagctgaa tgtataaggc atcgctaatt ttctcttccc gatcgttcaa ccgatccact
      181 aaaatttctt tgccctccag cgtttgaaaa acataccgtt gaatgttgcc taaaataaat
      241 gattccttcc atagaaccgg aatcttaacc ccctgaggaa ccggttcaaa ttgaatcagc
      301 tccggtctta aataataaat gcagcgattg cccttagcgg
//
LOCUS       DAIGTA010000227          339 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.240, whole genome shotgun sequence.
ACCESSION   DAIGTA010000227 DAIGTA010000000
VERSION     DAIGTA010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.240"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..>339)
                     /locus_tag="NOB43_002918"
     CDS             complement(<1..>339)
                     /locus_tag="NOB43_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983676.1"
                     /translation="QADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPLSALDARIR
                     KQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSKELYQNPQS
                     RFVAEFIGNYN"
BASE COUNT           87 a           96 c           71 g           85 t
ORIGIN      
        1 attatagttg ccgataaatt ccgcaacaaa tcggctctga ggattctgat acaattcctt
       61 cgaggtggaa acctgagcca cccgcccagc ttccatcaca aaaatccgat cactgattcg
      121 catcgcctct tcttggtcat gagtcacaaa aatcatcgtc atccctagcg attgctggat
      181 agcgcgcaaa tcccgctgca gctgttttct aattcgggca tccaaagcac ttaatggctc
      241 atccagcagc aggactttcg gttcagtgac caatgagcga gccagtgcca cccgttgtcg
      301 ttgaccgcca gaaagaaact ggacattttt atctgcctg
//
LOCUS       DAIGTA010000228          332 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.241, whole genome shotgun sequence.
ACCESSION   DAIGTA010000228 DAIGTA010000000
VERSION     DAIGTA010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.241"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>332
                     /locus_tag="NOB43_002919"
     CDS             <1..>332
                     /locus_tag="NOB43_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983677.1"
                     /translation="IILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAE
                     YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQ
                     GLYGWNVT"
BASE COUNT          103 a           53 c           78 g           98 t
ORIGIN      
        1 attatacttt ctttcttagg gaaagtacaa atggaagtga ttagtgcact gttgcaagaa
       61 aagtatcatg tggagataga actaaaagag cctacagtca tttatatgga gagaccgtta
      121 aaaaatgcag aatataccat tcacatcgaa gtgccgccaa atcctttctg ggcttccatt
      181 ggtttatctg tatcaccgct tccgttggga agtggaatgc agtatgagag ctcggtttct
      241 cttggatact taaatcaatc atttcaaaat gcagttatgg aagggatacg ctatggttgc
      301 gaacaaggat tatatggttg gaatgtgacg ga
//
LOCUS       DAIGTA010000229          321 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.242, whole genome shotgun sequence.
ACCESSION   DAIGTA010000229 DAIGTA010000000
VERSION     DAIGTA010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.242"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(69..321)
                     /locus_tag="NOB43_002920"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="NOB43_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAIGTA010000230          317 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.243, whole genome shotgun sequence.
ACCESSION   DAIGTA010000230 DAIGTA010000000
VERSION     DAIGTA010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.243"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..261)
                     /locus_tag="NOB43_002921"
     CDS             complement(<1..261)
                     /locus_tag="NOB43_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983678.1"
                     /translation="MNQFNKEIAQALLENTNLTEVFRNQLESTMNSLLESELTAILGY
                     DPYVRFNNGNYRNGDYTRRLDTQFGQINVRVPRDRKGEFHQSL"
BASE COUNT           86 a           56 c           63 g          112 t
ORIGIN      
        1 caacgattga tgaaactctc cttttctgtc cctagggaca cggacattga tttgaccaaa
       61 ctgtgtgtct agtcgtctgg tgtaatcgcc attgcgatag tttccgttat taaagcgcac
      121 ataaggatca tatcctaaaa tagcagtaag ttcgctttct aaaagagaat tcattgtact
      181 ttcaagttga ttgcgaaaaa cttctgttaa attggtattt tctagtagtg cttgagcgat
      241 ttctttgtta aactgattca tagggaagac ctccgtttga tttggtttag tcgctttaat
      301 catacgaata aggtctt
//
LOCUS       DAIGTA010000231          309 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.244, whole genome shotgun sequence.
ACCESSION   DAIGTA010000231 DAIGTA010000000
VERSION     DAIGTA010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.244"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="NOB43_002922"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="NOB43_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HCI0983679.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           97 a           45 c           50 g          117 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatat
//
LOCUS       DAIGTA010000232          308 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.245, whole genome shotgun sequence.
ACCESSION   DAIGTA010000232 DAIGTA010000000
VERSION     DAIGTA010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.245"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(<1..301)
                     /locus_tag="NOB43_002923"
     CDS             complement(<1..301)
                     /locus_tag="NOB43_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0983680.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLK"
BASE COUNT           96 a           76 c           47 g           89 t
ORIGIN      
        1 ccttcaaacc aaaggctaca ttttcaaaaa cagtcatagt tggaaacaat gcatactgtt
       61 gaaaaacaaa gccgatattg cgatccttcg taggcttatc ggcaatattc tcattgtcca
      121 gcacaatctc accgctcttt ggttgttcca atcccgtgat acagcgcagc aacgtagact
      181 ttccgcaccc gctgggacct agtaaagtaa ccagctcacc cttttcaatc tgaatttcat
      241 caatagctaa aatctgtttt tcatcaaaaa acagattgag atcatgtatt tctaaaaaca
      301 ttttccgt
//
LOCUS       DAIGTA010000233          301 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.246, whole genome shotgun sequence.
ACCESSION   DAIGTA010000233 DAIGTA010000000
VERSION     DAIGTA010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.246"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            91..>301
                     /locus_tag="NOB43_002924"
     CDS             91..>301
                     /locus_tag="NOB43_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0983681.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRL"
BASE COUNT          109 a           59 c           46 g           87 t
ORIGIN      
        1 catctttttt attttccaaa acatatagaa aagacacctt gaaatccttt agaattaatt
       61 tggcgaacca acccaaaagg aggaatcaag atgtcttaca ctcaccttat caaagaaaca
      121 ttagatattc tagacttatc agttactttt aacgaaaatt gtctcacaaa agaaaaatac
      181 aaagggcaaa tctgtcatat ttatcgtgga aacttgattt atacagccca agaatgcatc
      241 cactgtaaac accagattgc ttcagatatt gtgcgttggg gtacaacaac cgtccggttg
      301 t
//
LOCUS       DAIGTA010000234          292 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.247, whole genome shotgun sequence.
ACCESSION   DAIGTA010000234 DAIGTA010000000
VERSION     DAIGTA010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.247"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..185
                     /locus_tag="NOB43_002925"
     CDS             <1..185
                     /locus_tag="NOB43_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0983682.1"
                     /translation="YTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQ
                     RILDNELGCANASEAV"
BASE COUNT           83 a           63 c           69 g           77 t
ORIGIN      
        1 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
       61 ggaaccacct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      121 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      181 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      241 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tc
//
LOCUS       DAIGTA010000235          290 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.248, whole genome shotgun sequence.
ACCESSION   DAIGTA010000235 DAIGTA010000000
VERSION     DAIGTA010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.248"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            37..>290
                     /locus_tag="NOB43_002926"
     CDS             37..>290
                     /locus_tag="NOB43_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0983683.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
BASE COUNT           88 a           53 c           57 g           92 t
ORIGIN      
        1 atagatttat gaaaacgaat gcaaggagtg atagctatga tgtctaaaaa caatacgaat
       61 ggtagaaatc aatttgcgat gcttacgatt gatgatctag ttcctcaaga tcatctcgtt
      121 cgaaagattg atgccgcgct tgattttgaa tttatttatc caatcgtcga agccacttac
      181 tccgatttag gtcgcccaag tatcgatcca gtgattctga tcaaattggt gtttattcag
      241 tatttattcg gtatccgttc catgcgacaa accattaagg aagtcgatac
//
LOCUS       DAIGTA010000236          287 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.249, whole genome shotgun sequence.
ACCESSION   DAIGTA010000236 DAIGTA010000000
VERSION     DAIGTA010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.249"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>287
                     /locus_tag="NOB43_002927"
     CDS             <1..>287
                     /locus_tag="NOB43_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HCI0983684.1"
                     /translation="KAGFVTEDNLYLDSTHIKANANKHKFTKEMTHDEAKAYQDELED
                     EINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGEREKQFAYSA"
BASE COUNT          114 a           48 c           63 g           62 t
ORIGIN      
        1 aaagcaggtt ttgtaacaga ggataatttg tatctggatt ctacccacat caaagctaac
       61 gccaataaac ataagtttac gaaagaaatg acccatgatg aagcgaaagc ctatcaggat
      121 gaattagaag atgagatcaa tcgtcaacga atagaggctg gaaaacgccc ttttactttg
      181 gacttagaaa aggaagtgaa gctgaaagaa agaaaaataa gtaaagctga tccggaaagc
      241 ggctactacg tcaaaggcga acgagaaaaa caatttgctt attctgc
//
LOCUS       DAIGTA010000237          268 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.denovo.250, whole genome shotgun sequence.
ACCESSION   DAIGTA010000237 DAIGTA010000000
VERSION     DAIGTA010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.denovo.250"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
BASE COUNT           72 a           52 c           53 g           91 t
ORIGIN      
        1 agcctagcgt gagcggggcg gattgactgg caagtagatg ggtagctggc gtatgtccta
       61 aaaactgctt ctttccaagc aactcttcat aggcaaaaaa ctggaaagtc cactaacaag
      121 cccattcaga attccatttc aaaattttgt tgcctttttt gctgattttc aatcatttgt
      181 tgtgtgaatt cataatcctt tttagcacga tacattttta catcgtcatt cattatgcga
      241 ctgatttgat agtgaatctg tttagcag
//
LOCUS       DAIGTA010000238        23767 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.045, whole genome shotgun sequence.
ACCESSION   DAIGTA010000238 DAIGTA010000000
VERSION     DAIGTA010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.045"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..251
                     /locus_tag="NOB43_002928"
     CDS             <1..251
                     /locus_tag="NOB43_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0983685.1"
                     /translation="LEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDN
                     LIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            486..722
                     /locus_tag="NOB43_002929"
     CDS             486..722
                     /locus_tag="NOB43_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983686.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            729..2681
                     /locus_tag="NOB43_002930"
     CDS             729..2681
                     /locus_tag="NOB43_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI0983687.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2753..3250)
                     /gene="dfrG"
                     /locus_tag="NOB43_002931"
     CDS             complement(2753..3250)
                     /gene="dfrG"
                     /locus_tag="NOB43_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI0983688.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3612..4652
                     /locus_tag="NOB43_002932"
     CDS             3612..4652
                     /locus_tag="NOB43_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0983689.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4750..4938
                     /locus_tag="NOB43_002933"
     CDS             4750..4938
                     /locus_tag="NOB43_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI0983690.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4996..5349)
                     /locus_tag="NOB43_002934"
     CDS             complement(4996..5349)
                     /locus_tag="NOB43_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983691.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5880..6302
                     /locus_tag="NOB43_002935"
     CDS             5880..6302
                     /locus_tag="NOB43_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0983692.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6299..6529
                     /locus_tag="NOB43_002936"
     CDS             6299..6529
                     /locus_tag="NOB43_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983693.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            7027..7227
                     /locus_tag="NOB43_002937"
     CDS             7027..7227
                     /locus_tag="NOB43_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI0983694.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7254..8447
                     /locus_tag="NOB43_002938"
     CDS             7254..8447
                     /locus_tag="NOB43_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0983695.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8515..10080)
                     /gene="guaA"
                     /locus_tag="NOB43_002939"
     CDS             complement(8515..10080)
                     /gene="guaA"
                     /locus_tag="NOB43_002939"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI0983696.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10139..11062)
                     /locus_tag="NOB43_002940"
     CDS             complement(10139..11062)
                     /locus_tag="NOB43_002940"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI0983697.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11258..11863
                     /locus_tag="NOB43_002941"
     CDS             11258..11863
                     /locus_tag="NOB43_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0983698.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12171..13187
                     /locus_tag="NOB43_002942"
     CDS             12171..13187
                     /locus_tag="NOB43_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0983699.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13328..14629
                     /locus_tag="NOB43_002943"
     CDS             13328..14629
                     /locus_tag="NOB43_002943"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCI0983700.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14675..15337
                     /gene="deoC"
                     /locus_tag="NOB43_002944"
     CDS             14675..15337
                     /gene="deoC"
                     /locus_tag="NOB43_002944"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCI0983701.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15358..15756
                     /locus_tag="NOB43_002945"
     CDS             15358..15756
                     /locus_tag="NOB43_002945"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCI0983702.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15822..16904
                     /locus_tag="NOB43_002946"
     CDS             15822..16904
                     /locus_tag="NOB43_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0983703.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17116..18678
                     /locus_tag="NOB43_002947"
     CDS             17116..18678
                     /locus_tag="NOB43_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983704.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18671..19804
                     /locus_tag="NOB43_002948"
     CDS             18671..19804
                     /locus_tag="NOB43_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983705.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19804..20760
                     /locus_tag="NOB43_002949"
     CDS             19804..20760
                     /locus_tag="NOB43_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983706.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20859..22025
                     /gene="deoB"
                     /locus_tag="NOB43_002950"
     CDS             20859..22025
                     /gene="deoB"
                     /locus_tag="NOB43_002950"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCI0983707.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            22049..22867
                     /locus_tag="NOB43_002951"
     CDS             22049..22867
                     /locus_tag="NOB43_002951"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0983708.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22884..23591
                     /gene="deoD"
                     /locus_tag="NOB43_002952"
     CDS             22884..23591
                     /gene="deoD"
                     /locus_tag="NOB43_002952"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0983709.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         7735 a         4206 c         4956 g         6870 t
ORIGIN      
        1 ttttagagaa atatatgtcc ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa
       61 gcataagatt tcagaattgt tctctgttcc ctctttatca tggaagtgca aaaagtaata
      121 tagggattga taaccttata gaagttatta ctaataaatt ttattcatca acacatcgag
      181 gtccgtctga actttgcgga aatgttttca aaattgaata tacaaaaaaa agacaacgtc
      241 ttgcatatta agtagttcag ttttggagta caaaaagtga aaatgtaaac ctaaatgagt
      301 atcaaattgc aactgaattt gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa
      361 tttacaccac aaaatgtaag ttaaaatgta tataaaaatg cgaacgtgaa ataattattg
      421 taggaatgca aattggtgtg ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt
      481 ttcctatgca atttcttgag ccaaaaaata agaacgctaa gtctgtggat tgggaaatat
      541 cagagcaagt aagggtgata gttaagcaat acgctgaata tgcagagcgt actgaaagcg
      601 aagcagtgga tgaattctta ttgaacattt tagacgataa gaagtttatt gaatggattg
      661 ccaacaagcg aagtaataag cggattgttg aaaaaatggg tatcaaagat agagtgggtt
      721 gatagacaat gaccaagctt aaaagattag ccacgaagga agatgaaatt gtagatgtta
      781 aaattccgat ttcaaacgaa gaattaaaag atagggctaa acaatatgat ttattaactc
      841 caaaacgatt tgcaacaagg tataacaaaa tgttgttctt gccaacgtct tttaaatgga
      901 acggttctga atatcccatt caatataatt actgcatcaa tccgttttgt tgtaattttg
      961 ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc aagtcgatat aaaatgactg
     1021 gtagttccaa agataaaggt cataaaggta tgtactgcaa tgacaatcct attggcagag
     1081 gtgtatcgca aaactgtaca gtaacccctt tatctaattg gtctgttgtt gaagaaatta
     1141 aacgccttat agaaatcaat agcatccaag atgttgagcc agattatcaa tttcataaag
     1201 aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg
     1261 ggaaaagtag gggcaaatct caacgctatc aatgtaaggc gtgtaagaag ttcactaatg
     1321 ttctaccaaa aagagaagaa accactactt atcaccaaca aaagaacacc attcttccaa
     1381 tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg tacttgtgat attttaggaa
     1441 ttggagttgg aacctactat cataagctgg agtggctgta taggcgttgt ttggagtttt
     1501 tagaacgata tgagacacaa ccccttcaaa caaagaaatt taacgagatg tggcttaata
     1561 cggacaagat gcactactac ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat
     1621 atacggggtt tgaagacctt aatatgcaaa cgtatatagt tgtatctgct gaggtcttat
     1681 caagatatgt gttccgttct gatgttgcct atgattggaa tatttcaatg gatgaattaa
     1741 atgaagatac aagaaaattc aaagaagacc atctcaatac ttttagtcgt aaaaatgata
     1801 ggttagattg gtcttattat ccacaagaac catccgctaa cgatagcgaa aataggaatg
     1861 cttatcttca cgaattaggg aaaattacta ataggagtag atttgtcgat ggtttaaatg
     1921 ttgatgctcc ttatactaca actgctcact attggttaat taaacaaatg gttaatgccg
     1981 acgaatggcg aatgattagt gatgatgact tctctattag aaacgccttt tatagagtat
     2041 tcacgaaaga attaaggttg agcgatgcac atcattttat ttgccaagtt aacaagacga
     2101 aaagcagaaa acaatgctta aaagaattcg gacaagcaaa agcagaactg ctcgattggg
     2161 gagatatcag aggattcaaa acaaagtttc tacggacttt ggcatctcat tatctaactg
     2221 aattactaac aagtcatcaa ttccacgaag aggctattag taaagatgga gaaagatatc
     2281 gcaaatatgc cgataaccct atcaaacatc cattagccac taaggataaa ggattttatt
     2341 cagttgattg tagaacggat ttatctgctc tggaaccaaa cgaaatcgca aagatgctat
     2401 taaatgttaa tgaccattcg accaatagct ttattcaaca gataagacgt tatatatcat
     2461 ctcttgaaag accattaaca acagctcgtg gtgataagaa gagctatatt tacgctaact
     2521 tcaatccgaa gtatgctcaa tttgcgatta caattctaag aacttactac aacttttgtc
     2581 gcccttttaa atcagcggat aaaaaggttt tgacacctgc tcaaagatta gggattacag
     2641 ataaacaatt tgattggaaa gatataattt atttcaaatg acaaaaagag cttggagtaa
     2701 tcccaagctc ttgtgcttta tctttactgt tcttcttcaa ttaacgcacc cgttaactca
     2761 ataagttttt tctttcatat acatgaaaat agtagttata cggattttta tcattcttta
     2821 tccctttttg ggcaaatacc tcattccatt cctcataatt cacttctgga aaaaaagtat
     2881 ctccttcgaa ttcatgatgt atttttgtga tgtacatttt ctcaacataa gggaaaaaca
     2941 aattataaat ctgttctcct ccgaaaataa aaatttcttc ttcgttttta cataactcaa
     3001 aaacatcttc tattgaatga acaatttcac aaccattaaa ggtaaacccc ttatctctcg
     3061 tcagaataat atttcttctg tcaggtaagg ctcttccgat tgattcaagg ttcttcctac
     3121 ctaatattat cggatgtccc tttgtagtat ttttaacata ttcccagtcc ttgggaatcc
     3181 tccaaggaat gtcattctct ttgccaatca ctctattctt atccatcgca gcaatcaaag
     3241 aaactttcat ttataacaca gcctttttaa ctaatttacc atctaatttc ttatttctat
     3301 caaaaaacct tttctcatta tcctgcccgt tagttgaata agcaattttt tctataagtt
     3361 atattatcat aataccacaa aatcacaaat tttcattcaa ttatcatttt caattgcatt
     3421 ttataaatca ttttgtatgt aatttggtat gtaagttaaa atgaaaaaag tagtccattt
     3481 tgaagtacat tttgtcattt tgtactccaa aactgaacta cttacttgca tatatacgcc
     3541 tttatagtgg agtactacat ttacgagatt cggttagagt atcagaaaaa gaaaaaataa
     3601 aagttacaga aatgtatact tcaataaatg gtgaattatg taagattgat agagcttatt
     3661 ctggagaaat tgttattttg caaaatgagt ttttgaagtt aaatagtgtt cttggagata
     3721 caaaactatt gccacagaga aaaaagattg aaaatccgca ccctctacta caaacaactg
     3781 ttgaaccgag taaacctgaa cagagagaaa tgttgcttga tgcccttttg gaaatctcag
     3841 atagtgatcc gcttctacga tattacgtgg attctacgac acatgaaatt atactttctt
     3901 tcttagggaa agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg
     3961 agatagaact aaaagagcct acagtcattt atatggagag accgttaaaa aatgcagaat
     4021 ataccattca catcgaagtg ccgccaaatc ctttctgggc ttccattggt ttatctgtat
     4081 caccgcttcc gttgggaagt ggaatgcagt atgagagctc ggtttctctt ggatacttaa
     4141 atcaatcatt tcaaaatgca gttatggaag ggatacgcta tggttgcgaa caaggattat
     4201 atggttggaa tgtgacggat tgtaaaatct gttttaagta cggtttatac tatagccctg
     4261 ttagtactcc agcagatttt cggatgctta ctcctattgt actggagcaa gcctttagaa
     4321 aagctggaac agaattgtta gagccatatc ttagttttaa agtttatgca ccacaggaat
     4381 atctttcacg ggcatataac gatgctccca aatattgtgc aaatatcgta aatactcaac
     4441 tgaaaaataa tgaggtcatt attattggag aaattcctgc tcgatgtatt caagattatc
     4501 gcaatgattt aacttttttt acaaatgggc ttagtgtttg tttagcagag ctaaaaggat
     4561 atcaggttac cactggcgaa cctgtttgcc agacccgtcg tctaaatagt cggatagata
     4621 aagtaagata tatgttcaat aaaataactt agtgcgtttt atgttgttat ataaatatgg
     4681 tttcttatta aataagatga aatattcttt aatatagatt tgaattaaag tggaaaggag
     4741 gagattgtta ttataaacta caagtggata ttgtgtccta tttgtggaaa taaaacaaga
     4801 ctacgaatac gagtggatac tatacttaaa aatttccctt tatactgccc caaatgtaag
     4861 aacgaaactt taattaatgt tcaaaaaatg aatataataa caatcaaaga gccagacgcc
     4921 aagacgcaga gccgataatt tgagaaatga aactctcatc ttatcggctc tttttgttta
     4981 tctgaatttt actgactagc cttcaatatt tcttgcttca ttgatacctt ttgctagtgc
     5041 ttccattaag gatagttctt tgtctgtaaa gctatccatg tatttttcta cctgtaacct
     5101 tcgagtgctt ttaatcaaat tatctgtagg taagaaaaat tcatcaatag atacatggag
     5161 taatgataca agatcataca gcacttgtgt acttgggtgt tgtcctttgt tttctatatt
     5221 tgttaaataa cgtgggtcaa tttcaatcat tgttcccact tgttcacgag tgagaccccg
     5281 tttcattcga gcctctttaa tcgctaaacc aacggctcta aaatcgtatt tatcttcttt
     5341 tttacgcata ctaaatcacc tctatacatt ttactgttcc tatataacca taaacaggta
     5401 tagaaaaaca tgttatatag tttatgagtt cctatagaac actgtggaat ttattaatgc
     5461 gatgaatcca atttcaaata gaaaggtcgc tgattttatt tacctataca actttataaa
     5521 atttagtcat actcctagaa agtagataaa attggcgact taatggaggg aaaagtcgcc
     5581 atgagaaaga taatctgtca tctagttctc ttaattaagt tcttatcaaa aaaacttatc
     5641 cacctgtact ggatagatat gaccatcaat gtggttttgc agattacata gatagaaaaa
     5701 tcaaagcata tgaacagaga aaacaatctg tttatgtgct tttttggtca cttaataaat
     5761 atcttttagg atttctcttc atttatgcaa caaatccccc gttcgtgtcg gggtttagta
     5821 tgaagggaga taaagaagca catgccactc cctttcacga cagaaagggg gtgaaaagca
     5881 tgaaaccatc ttcttttcaa gaaaccatag aaaatcagtt tgactatatc tgcaaacaag
     5941 ttattgaaga tgaacgaaaa gattacttca aacatctaga cagactatca gcaaaagaag
     6001 tctcgttttc tgatatagat aactaccttg tcaactcttt ttctactgtt gatacgtacg
     6061 tcactgattt ccaactattt aaattatttg gattaagaat caatgttgaa agtgatttat
     6121 taagtgaagc cctgcgtcat ctttcagaga aaaaacggaa cattatttta cttcattact
     6181 ttatggatat gagtgatgtg gagattgcgg agttactaaa tttgaatcgt tcgactgttt
     6241 atcgtcatcg aataagtgga ctagccatga ttaaagaatt catgaaggag tgtaaagaat
     6301 gaaaacagct tatccaaggg ttcccttccc cctcattgta aaggcgacag atggcgacgt
     6361 ggaagcaatt aatcagattg ttaaacatta tcgagggtat acctcaaaac gttcattacg
     6421 tcgcatgaca gacgaatatg gaaattctca tatggttatt gatgaaaccc tacgtggcag
     6481 aatggaaacg aaactcatct ctaagatttt atcgttcgaa attaaatagt cccatttttt
     6541 cgtggaagcg tgtcgaatcg tatccacgct tcccgatttg ggaggtttgt tattccatca
     6601 aagcatattg tgtgttcagt aggttttgat aggctaacaa gccaaacgtt ctttgacaac
     6661 caaataaagg caatcgaata cgtttcggta agaaaagagc tgatgaacta acacgccatg
     6721 acctacaaaa ttagtgagcg attcatgtta gtaattcgaa agtaatcttt agcaggattg
     6781 ctgccatgac tttcttatcg tgataatgat actcccgtat agccatagtc cgagcgttag
     6841 aagcgtcaca ggcaatgggt acggctacat gagaaccatg cagaagtgaa attcctgtga
     6901 gctttgctag agctgttcga ttgctaagat attcttctct tgtcagtgta ttattataaa
     6961 actatttgat ataattatag gtgaatattg gagttttcct agcctataat tgggaaagga
     7021 gtaataatga taacggtcac aaaaaaggat ttagttgagc taggatatgg aacttctttt
     7081 tcagcagaca tcataaaaaa agcaaaagaa ttgatgatta caaaagggca tatctactat
     7141 caatctcgaa agctagatag agtccctcgt gaagctgttg aagaaattct aggaattcgg
     7201 ttttcaaatg aaaacaggtc tgagtagttt ttgcacagta aggagtaaaa actatggtta
     7261 aagacccaat aaaaaaagca aagaatggaa cctattattt tcgtgcaaat ctaggttatg
     7321 attctaaagg gaaaaaaatt caaaaatatc gtagtggatt cactactaaa aaagaagcaa
     7381 gagaagaata ttcgaaactg ctattgatga aaccagaaga attaagtgag aataaggata
     7441 aaatgacgtt taaacattat atctttgaaa ttttccttcc atggtataag acacaggtaa
     7501 agctcagaac atatgaaaat cgcttaccaa ctattaagaa gcatttctct tattttgata
     7561 aaatggctgt ttccgatatt gagcctattg atgtgcaaaa ttggcaacta aaattatcaa
     7621 agaagtgtaa gtcttcttat gtaagagctg ttcaaggact attttcagtt gctatggatc
     7681 gagcaattgt ccttgggata accaccacaa atccatctaa gattattggc aatgtgaaaa
     7741 agcaaaagtc taaaattgaa ttttggacaa aagaagaatt tgaaaaagta atctctctaa
     7801 tttacaaaga agattactat caacactttt tatttatctc tctgtggttt ttatttatga
     7861 ctggaatgcg aattggtgaa gctactgcca ttcaatggga agatattgat tttgactcag
     7921 gagtactaac catcaacaaa acactctatt acaagaatca atcgaattat agatttgttg
     7981 aaccaaaaac aaaggcgagc gttcgtcata ttgtattaga taaatgcaca ttaacttatt
     8041 tatccgaatg gaaggaagta caacaaaatc taattcagac agactttgta atgagctata
     8101 acggtattcc tacccaaaaa catacactat catatgctat tgaacgctat gctaagctgg
     8161 ctggtatcca tcgaatcaga atccatgggt tacggcattc tcatgcttcc ttgttaatca
     8221 gtatgggaga aaatccactt atcattaaag atcgtctagg acacgaagat attgagacga
     8281 ctttaggaac gtatggacat ctttatccta acagtaattt cgaggtagct aacaaattaa
     8341 atggagccat ttcctttaaa gaagcaaaac aaaattatga tacttcacca aagaatcaat
     8401 ttactgtaga ctacttgcga aacaaagaaa tgaaaaaagt gcaataaaag tgcagtaaaa
     8461 agataagaag agccagaaac ccttggtata agaggatttc tagctctcct acaactattc
     8521 ccactccact gttgctggtg gtttagaagt gatgtcatac acgatacggt tgacgtgggc
     8581 tacttcgttt acgatacgta cagagatttt ttgcaagact tcccatggga tacgggcaaa
     8641 gtcagcggtc attccgtcga ttgaagttac agcacggata ccgactgtgt agtcgtaagt
     8701 acgtccgtca cccataacac cgacagagcg gatccctgga agaacagtga aatattgcca
     8761 gatatcacgg tcaagtccag cagctgcgat ttcttcacgc aagatagcat cagattcgcg
     8821 tacgatttct agcttgtctt cagtgatttc gccaagaaca cgaataccaa gaccaggacc
     8881 agggaatggc tgacgccaaa cgattgaatc aggcatgcct aactgagtcc ctaattcacg
     8941 gacttcgtct ttgaataatg tgtttaatgg ttcgatcaat tcaaattgca tatcttctgg
     9001 cagtccacct acattatggt gagatttgat cgtctgtgct gtttctgtac cagattcgat
     9061 aacgtcagta tacaacgttc cttgtgctag gaaagagacg ccttcttcac cagcaagttt
     9121 tgttgcttcg tcatcaaaaa catatacgaa ttcattccca atgattttac gtttttgttc
     9181 tgggtcagat acacctttca acttgtctaa gaagcgatct cttgcatcga ctttgatgat
     9241 gttcaagccg aattttccgc ctagactttc cattacttgt tccgcttcgc ctttgcgtag
     9301 cagaccgtgg tcaacaaaga tagatgtcaa ttggtcaccg atcgcttttt gtaaaagaac
     9361 cccaacgaca ctagaatcaa cgccacctga aagaccaagc aagacttttt tgtcaccaac
     9421 ttgttcacgg attttttcta cttgcatatc gataaagtta tccattgtcc agttaccttc
     9481 acagtgacaa acatcaaagg caaagtggcg cagcaattcg attccgtatt cggaatgacg
     9541 tacttctgca tggaattgga taccataaaa attacgtgtt gtgtcttgga tagaagcaat
     9601 cggacaatct ttgcttgttc cgactgtttc aaagccttca ggaactttag ttaccaagtc
     9661 accatggctc atccatactg tttgttgttt tggtgtttct ttaaacaaga cagcttgatc
     9721 gcttgttact tctaacaagg ctttcccata ttcgcggttt ttagcaggct ctacggaacc
     9781 gccaagtttg tacgtgatca attgcatacc atagcaaatc cctaatacag gaatacctaa
     9841 attgaagatc tcaggatcga tcccaaatgc attctcatca tatacactgt ttggtccgcc
     9901 agaaagaatg attccctttg gattcatcgc ttttacttct tctgcagtaa tgcggtggct
     9961 caataattcg gaaaagactc caagatcacg aatacgtctt gtgatcaatt ggttatactg
    10021 actaccgtag tctaatacga taatcttttc aacgttcgtc atatcggcaa cgtttgtcaa
    10081 atttattacc cctatccctt taaattttat ctcaaaatag tcaaactatt ttaaaatgct
    10141 aatattttcg catgaaaatc gaatcgatga tatgattttc agttttatgg agaattatat
    10201 cggctcttcc tcgtgtaggc aagatatatt cctgtaaatt tttcaaattc acatttttcc
    10261 atacatcttt tgccatttta aaggcttctt cacgatctcc gatagcaaaa cgataataat
    10321 aattctctgg attttggaaa gccgtatcca gtaacgcacc aaaacgatcc aaataccatt
    10381 tttcgatcag cacgggatcg gcatcgacat agacagaaaa atcaaaaaag tcgctgacgt
    10441 agatttgctg attcgcaggt aattgaagcg tattgatccc ctcaacgatc aagatatcag
    10501 gctgctggat caattcgtac ttgtctggaa tgatatcata cacatcatgt gagtaaacag
    10561 gtacttttat ctcttcctga ccagatttta cacggttcaa gaaatcgatc agcatctcca
    10621 tatcataact ttcaggaaat cctttacggt ccatgattcc acgctctttt aatatacgat
    10681 ttggataaag aaatccgtca gtcgtgatca gctgaacgtt tcttcgtttg aaggtacgag
    10741 acaaaatcgt ctgcagcagt ctggctgttg tactttttcc aacggctaca cttccggcga
    10801 tcccgataat aaaaggcggt acttctacgt atttatgaag aaataaacct ttactcaaga
    10861 acaaagattc aaattctttc atataaagat aaatcagatg agcaagaggt acatagatat
    10921 ctcgaacatc ctgcatggaa atgcggtcat tcaaactttt gatattatct agttcatctt
    10981 gtgtcaaagg tgcttgccca ttacgataaa attctcgcca ttcttctctt gccacacggt
    11041 agtagttcat tggatcattc atattagcct cctgcgttct cccatcaatg gaactatttt
    11101 aacacaaaat aaacgcaaac cccaccactt aagagagatt gccgatcttt ttgtataatc
    11161 tttataatag aaagaaacgg agtcttattc ttgacttgcg cacggataca taaaaggata
    11221 gactgttgtc atgaaagaaa tgagaaggat ggaagacatg acaaatcatt actattctga
    11281 acgcccagat acggcgcacg attttgaaca atgggctttt gagttaaaag gcagaacctt
    11341 tcaatttgta acagattctg gtgtattttc acgtgaaaca gtggattatg gttcacgtgt
    11401 cctgattgat gctttcgatt gggaagagtt acctgatgaa ggaaagatct tagatgtggg
    11461 atgcgggtat ggaccgattg ggttagcttt ggcatttgcg acacagcggt ttgttgaaat
    11521 ggtcgacatt aatgaacgag cggtaagtct agcgcaagga aacgcaaagc gtaaccaaat
    11581 cgaacatgtt gatatccatc aatcgaatat ctatgaagca gttcatgaag aaacctatgc
    11641 agctatcgta agcaatccgc cgatccgtgc tggaaaaaaa gttgtacatg aaattttgac
    11701 aggcgcatat cctcggttga agaagggcgg tacactgaca attgtgatcc agaagaaaca
    11761 aggagcgccg agtgcgcaaa agaaaatgga agaaacattt ggtaatgcag aaatcgtcac
    11821 aaaagataaa ggatattata tcatcaaaag tgtgaaagaa taactagctg aaaaatagtg
    11881 gagcgacgaa agagtggaac tgggcgtgca tgtacgggta cgtatcagtt ctttttttgt
    11941 tgagaagttt ttaaaaacaa agaactattt tttcttcaaa aagaaatagt aggaacagag
    12001 tcgttgtttt ttacgataaa ataaataaga tacagaactt gtatagaagg ctgccaagtc
    12061 ggtagataaa ggaggttttt atcaaaaaac atactttcct tttttctcta ttcttttctt
    12121 gggggttttg gtacactgat agggaattta gatagaaggg agccaatagg atgaagctga
    12181 ccatcagaga tatcgcagaa atggcaggcg tatcagtaac aactgtctca cagattttga
    12241 ataacaaagg aagcagattt agtgataaga caagaaaaaa agtgttgtcg atcgtgaatg
    12301 aacatcatta taagcccgat tatttcgctt caaatgtgat caatcgacat tcaaagacca
    12361 tcggaatgat cgtccctgat gtcactgatt tcttcttctc caaactgatc gaaggtgtag
    12421 agagctattt gaatcctttg ggctatgtga tcatgttatg caattctcgt catagccaag
    12481 aaaatgagat caagtattta caagagcttt cccaccgctc agtggacgga atcttgctgg
    12541 ccacaccaaa tattttacct gagaaatatg cattagacag cggtttttat caaaaaatgc
    12601 caatcatttt aatcgatcgc ggattgaatc gtcgggataa cggacggctt atcgtaaagg
    12661 aatatgaggg cgcctatcaa gctgtttcgc tgtttattga aaatggccat acgaagatcg
    12721 gcatgctgaa ggaaaccact ggatactatc aattagaaga acgtttcaac ggatatcgtc
    12781 atgcgctgaa agatcatggc ctgcctttta atgggaaatt tgttgaacat ggagagttga
    12841 ctgtccaagg tggatatact gcatcaaaaa aattactcaa acataaagat atcacggcta
    12901 ttttttgcgg gaatgatgcc atggcgatcg gatgctatca ggcgatcgat gaattgggca
    12961 aaaaaatccc agaagatatc tcagtcatag gattcgatgg attaaagctg tcagaataca
    13021 tgattccgca attgacgaca gtgcagcagc caagttttga tattggattt tatgctgcac
    13081 gtttcctgat cgatacgatc gaatttcctc aaagaaaagt tccgaacaaa gtgttcgaaa
    13141 caaaattaat tattcgtgag agcgtaaaag tattgacaaa gggctaactc ggcggtatat
    13201 tgcttatgta agcatttaca aaggctagtt agtgcttttt ttatttttag taaaccagtt
    13261 tactaaagtg gtttaccttt cctaaaaata atgtataata ccgaatgaag acaaggagga
    13321 tcaggcaatg cgaatggtgg atctgattga aaaaaagagg gatggaaacg agctgtcgaa
    13381 agaggaaatc gagtacatcg tcacgaacta tacgaatgga aagattccag attatcaagt
    13441 cagtgcatta ttgatggcaa ttttttatca agacatgaca aatgaagaaa tcacgaactt
    13501 aacattggcg attgctaatt ctggtgatgt catcgatttg agttctcttg aaggaataaa
    13561 ggtagataag cattcgacag gtggcgttgg tgacacgacc acattgattt tagcccccct
    13621 agtagctagt gtcggagtga cagtggctaa aatgtctgga cgcggtctag gttacacagg
    13681 tggtacacta gacaagctag aagcaattcc cggatttcag atcgagcttt cggatgaaga
    13741 atttgtacgc attgttaatg aaagtaaagt agcggtaatt ggtcaatcag gaaacttggc
    13801 accggcggac aaaaaattgt atgccttgcg tgacgtcaca gcgaccgttg attctcttcc
    13861 gctgattgcc agttcgatta tgagtaaaaa aatcgcggca ggagcagatg caatcgtttt
    13921 ggatgtgacc actggagacg gtgctttcat gaagaacatc gaagatgcaa gacgtctggc
    13981 aaagaccatg acgagcattg ggaaactggc taaccgagaa acagtggcgg ttatctcaga
    14041 tatgtcagaa cctcttggcg aagctatcgg aaatagtcta gaagttgtcg aggcaatcga
    14101 aacattacaa ggaaatggtc cagaagatct agtagaaatg tgctacgcct taggaagcca
    14161 aatggttgtt cttgctggca aagctaagac aaccgatgaa gcaagaacgt tgcttcaaga
    14221 agctctggaa tcaggtaaag cgttagcaaa attcaaagaa atgatccaaa atcaaggggg
    14281 agacccagcg atcgtggaac atccagaacg aattttgact gcacgctaca caatggagct
    14341 tcctgctaaa caaagcggag ttgtgtcaaa aatcgtggca aatgaattag gaattgctgc
    14401 aatgatgcta ggtgctgggc gtaaaaccaa agaagaagat attgatcacg ctgttggatt
    14461 gaaactgcat aaaaaaattg gtgacactgt gacaaaaggt gagtcactat tgacgatcta
    14521 tagtaacgac gaagaaatca cttctgtcat tgaattatta tataaaaata ttgaaattgg
    14581 tgaatcggca atgaagccaa cgttgattca tgacatcatc acagaataaa ggaaaaaagc
    14641 ggactttacc gttttaaaga aaaggggaaa agaaatggaa ctaaaccgaa tgatcgacca
    14701 tactattttg aaagcagacg catctaaaga agctgtgatg caaattatcg aagaagcaaa
    14761 aaaataccat ttttattctg tctgcatcaa tccagcatgg gttgcgctag cgaaagaaca
    14821 attacaaggt gagccagtag ccgtatgtac agtaatcggg tttcctctag gagcaaacac
    14881 acccgagaca aaagcatttg aaacaacaga tgccatcaat aacggtgcag atgaagtcga
    14941 tatggtcatc aatatcggtg ctttgaaatc aaaggatgat caacaagtcc aaaaagatat
    15001 cgaagcagtt gttgaagcag caaaagatcg tgcgcttgtc aaagttatta ttgaaacatc
    15061 gttattagat agagaagaaa tcatccgagc ttgcgaaata gcaaaagctg caggcgctga
    15121 ttttgtcaaa acatcaactg gtttctcaac aggcggagca aaggtagagg atgtccgttt
    15181 gatgcgtgaa actgtaggac cagaaatggg tgtcaaagct tccggcggta tccataacga
    15241 agaagaagca atggcaatga tcgaagctgg tgctacaaga atcggaacaa gcgcaggagt
    15301 agcaatcgta tctggttcaa ctggtgaagg ctattaattt tttcaaagga gaagctcatg
    15361 gcagaactca aacaagaatg gatcaacaca gctattgaag cgttagataa agcctatgtt
    15421 ccttattccc attttccggt aggcgcttgt ctcgtaacgg aatcaggcaa gatttatcaa
    15481 ggcatcaaca ttgagaatgc atcatttgga ttaacgaatt gtgccgagcg cacagctttt
    15541 ttcaaagcag tatctgaagg agaaaaaaca tttacgcatc tagtcgtagc ggggcacacc
    15601 cccgatccta tctctccttg tggtgcatgt cgacaagtaa tggcagaatt ctgttcccct
    15661 gatatgccgg ttacgctagt aggagacaat ggtgtgacga aggcaacgac cgttcgtgca
    15721 ctgctgcctt atgcatttac tgaaaaagat ctataactca tgttcattca gtcagctgac
    15781 tgttgaaaaa taaaacaatt attttaggag gctttacaga aatgaaaaaa gcaaaattat
    15841 ttggtttagg tgctgtcgca ctagcagcag ggttattttt aggtgcatgc ggcaacaacg
    15901 gctctactga ttcatccggt ggcaaaagct catcagacac aacaactgca gcattgatca
    15961 cagacacagg tggtgtagac gaccgttcat tcaaccagtc agcttgggaa ggactagaaa
    16021 aatgggggaa agatcaagga ctttcacgag gaaatgatgg cttccaatat ttccaatctt
    16081 caaatgaatc agattacatc ccaaatattg accaagcatt gaatgctgga ttcaaaacga
    16141 tttttggtat tggttataaa ctaaaaccag cgatccaaga acaagcaaca aacaatacag
    16201 gtacgaactt tgttattatc gatgatgtca tcgatggatt agataacgtt gtatctgcaa
    16261 ctttcaaaga caacgaagct tcttatcttg caggtgttgc agcagcttat acgactgaaa
    16321 caaacgtagt cggctttatc ggcggtgtaa aaggtgaagt aatcgatcgt tttgatgctg
    16381 gattcaaagc cggtgttgat gcaggtgcga aagaattagg aaaagaaatc aaagtattga
    16441 atcaatatgc tggtgacttc tctgctccag ataaaggacg ttcaattgct caaggtatgt
    16501 atgcacaaaa cgcagatatc atcttccatg cttcaggcgg tacaggtaac ggtgtattcc
    16561 aagaagcaaa atcattgaac gaatcaggcg acaaaaaagt ttgggttatc ggtgttgacc
    16621 gcgaccaatc agacgaaggc gaatacacat taaacggcga aaagaaaaac ttcacattga
    16681 catctacact gaaagcagtt ggaacagtag tagaagattt ggcacaaaaa tcagcggacg
    16741 gtaaattccc tggcggcgaa cacactgttt atggattgaa agaagacggt gttggtctaa
    16801 cagaaggaca actttctgac gaagcgaaaa aagcagttga tgaagcaaaa gaaaaaatca
    16861 tttcaggtga cgtaaaagtt ccagaaactc ctgaagaaaa ctaaaaccat ttctatagcc
    16921 ttgttagaca catgtttgac aaggctatgg tttgattaga acaagaattg ttcatttatc
    16981 caagctgcct tgtgacagtt tggataaggg aacaactccc tgaagtaatg tttgtttcaa
    17041 aagaagaacg ctcactaagc gtgaatctta gtcaatcgtt gccctagata gaaatcgtta
    17101 ggatgtgaaa aaaaggtggt tcaagaaaat attgtcatag aaatgcagaa tattaccaaa
    17161 gaatttggaa cattcaaggc aaatgacaac atcaatttac aagtaaaggc aggagaaatt
    17221 catgcgttgc ttggagaaaa cggtgctggc aaatctacat tgatgaacgt gctttccgga
    17281 ttattagagc cgacatcagg gaaaattttg atgcgtggga aagaagtaaa gatcacaagt
    17341 ccgaccaaag ccaaccaatt agggattggg atggtccatc agcactttat gcttgttgat
    17401 gcctttactg taacagaaaa catcgtgttg ggaagcgagc ctagtcgcgc agggatgctt
    17461 gaccataaaa aagcacgaaa agagatccaa aaagtttctg aacagtatgg attgtcagtc
    17521 aacccagatg cttacgttcg tgatatttca gttggaatgg aacaacgggt agaaatttta
    17581 aaaacacttt accgaggagc agatgtactg atttttgatg agccgacagc tgtattgacc
    17641 cctcaagaaa ttgatgaatt aatcgtgatc atgaaggaat tagtcaaaga aggcaagtcg
    17701 atcattttga ttacgcataa gttagatgaa atcaaagcag tagctgaccg ctgtacagtt
    17761 atccgccgtg gaaaaggaat cggtacagtc aacgttaaag acgtaacctc acaacaatta
    17821 gccgatatga tggttggaag aacggtttca ttcaaaacga tgaaaaaaga agcgaagcct
    17881 caagaagtcg ttttgtctat tgaaaatcta gtggtgaaag aaaatcgtgg attagaagcc
    17941 gtgaaaaact tgaacttaga ggttcgtgct ggcgaagtac ttggtatcgc tggaatcgat
    18001 ggaaacgggc agtcggagtt gatccaagct ttgactggtt tgcgaaaggc agaaagcgga
    18061 catatcaagc taaaagggga agacatcact aataaaaaac cccgaaaaat cactgaacat
    18121 ggtgtaggac acgtgccaga agaccgtcat aaatacgggt tagtcctaga tatgacatta
    18181 tctgaaaata tcgcactaca aacctatcat caaaaacctt acagtaaaaa cggcatgctg
    18241 aattattcag taatgaatga acatgccaga gaattgatcg aagaatatga tgttcgaaca
    18301 acgaatgaac ttgttcccgc aaaagcttta tcaggcggaa atcagcaaaa agcaattatc
    18361 gctcgtgaag tcgaccgaga tcctgatctg ttgattgttg caaatccaac tcgtggactg
    18421 gatgtaggtg cgatcgaatt tattcataaa cgtctgatcg aacaaaggga caaatacaaa
    18481 gcagtgttac tgatcagttt cgaattagaa gaaattttaa atgtttcgga tcgtattgct
    18541 gttatccatg aaggagaaat tgtcggtatc gttgatccga aagaaacatc tgaaaatgaa
    18601 ttaggtctat tgatggcggg ctatacctta gaagaagcac gaaaagagtt agaaaagggg
    18661 gctggcgcac atgaatgatc gcagcgaaaa attccgtaat ttattagtgc ctgtactttc
    18721 agttgtttta ggattgatct taggcgcgat attgatggct gcttttggtt ttcagcccat
    18781 ccaaggttat tcttctatgc tagatgcagc ccttggttcg caaagaggga taggtgaaac
    18841 gttaaggcaa gcaacgccgt tgatttttac agcattaggt ttttctgtag ctaactcagc
    18901 tgggtttttc aatattgggc tttctggaca agcactttgc gggtggatcg tcagtgtctg
    18961 ggtggcactt gcgtttccag atctgccaaa agttgttttg cttccgttat gcgtgatctt
    19021 aggtgcctta gctggtgcga tggcagcggc tgttccaggt ttacttcgag cattttttgg
    19081 aacaagtgaa gtgatcgtaa caatcatgat gaactatatc ttattatacg taagcacatt
    19141 tgctttacat gaagtgatgc ctgaaagcta tcgctcaagt ttggactctt ccaatatgat
    19201 cagtcaaaat gcctcactgc ggttaccatg gttaacacaa gcttttggcg gctctcgcgt
    19261 aaactcagga ttatttttag caatcatcgc gcttattttc gtttggctgc tgatgaagaa
    19321 aacgacttta ggatttgaaa tccgttctgt tggattgaat ccttttgctt ctgagtatgc
    19381 aggaatgagt agtaaacgta cgatcgtttt gtcgatggtc atttctggcg ctttggcagg
    19441 gcttggcggt gtggttgaag gattaggaac gtatcaaaac ttctttgttc aaacgacttc
    19501 gctatctatt ggatttgacg gaatggctgt ttccttgctt ggttctggat cagcaatcgg
    19561 tattctttta tcagcgatct tgttcagtat tttgaagatc ggtggacttg gcatgcagac
    19621 aggagcaggt gttccgtttg agatcgtcaa tgtatcgatt gctttgatta tcttctttgt
    19681 cgggatcaac ttcctgattc gtttcgtcat ggctaaagtc ttccaaggga aaaaacaaga
    19741 agagatcgtt gcgacaatag aatcgaaacc aacgaatcaa aaccatgaag ggggcgaact
    19801 ataatgtcga ctatcgaatt aattgccttg atccttactt ctacactggt ttattcaaca
    19861 ccgctaattc taacgtcact aggcggaact ttttctgaac gaagcgggat cgtaaacgta
    19921 gggctagagg gaatcatggt catgggtgct tttagttcca tcgttttcaa cttgacgatg
    19981 agtccatcac ttggttctat gacaccatgg atcgctattt tagtgggtgg cgtcgtaggt
    20041 atcctatttt ctctgattca cgcagtagca acagtcagtt tgcgtgctga ccatattatc
    20101 agcgggacag taattaatct gatggcacct gctttaggtg ttttcttgat caaagcatgg
    20161 tatggtaaag gtcaaactga taacatcacg cagaatctgg ggtatttttc tttcccagga
    20221 ttagcagata ttccggtcat tggaccaatt ttctttaaaa atacattctt acctgcttat
    20281 tgtgctattt tgattgctgt cctagcttgg gtgatcatct tcaagacgaa attcggcttg
    20341 cgcctccgtt cagttggtga aaatcctcaa gctgccgaca cattaggtat caatgtatat
    20401 gctatgcgtt attcaggcgt actgatttct ggcttgttag gcggtatggg cggtgctgtt
    20461 tttgctcagt cgatttccgg taacttttca gctggtacga tcgttggaca agggttcatc
    20521 tccatggctg ctatgatctt tggtaagtgg aatcctttag gggcaatggg tgcctcattg
    20581 ttctttggtt ttgctcaaag cttgagtatc attggcgcac aattaccagt tatttcttcg
    20641 attccgccag tattgctgca aattgctcca tatttgctga caatcattgt gctggttgtt
    20701 ttcttaggga aagcttctgg tccaaaagca aacgggaaga actatatcaa atcaaaataa
    20761 tcttttagcg aataaaaagg gtgggttacg ggaagtgttt ttcgtctcgc cctttttgtt
    20821 ttaaaggcaa taaaaataaa aagaaagaag gaataatcat gtttaaacgc gtacatctga
    20881 tcgtcatgga ttcagtagga attggagaag caccagatgc cgataagttc ggtgatgttg
    20941 gttctgatac attaggacac attgcgaaag aagcaggatt gaacgttcca catttagagc
    21001 agcttggttt aggaacgatc cgtcctcttg aaggtgtgga atcagtgaaa gatcatcaag
    21061 gctatgcgac gaaattagaa gaagtttctg tagggaaaga tacgatgaca ggccactggg
    21121 aaatcatggg attgaatatc aaaactccat ttcgtgtgtt tcctaatgga ttccctgatg
    21181 atctgatcaa acaaatcgaa gaattttctg gccgtaaagt cgtatgtaac aaaccttata
    21241 gcggaacagc tgttattgac gattacggtg aacaccaaat gaaaacaggc gatttaattg
    21301 tatatacttc tgccgatcct gtccttcaga tcgcggcaca tgaagaaatc attcctttag
    21361 aagaattata tcggatttgc caattcgttc gtgatataac aaaagatgat ccgtatatga
    21421 ttggccgaat cattgcacgt ccgtacgtgg gtgaaccagg agacttcaca cgaacaagca
    21481 atcgccatga ttatgcgttg aatccattcg gacacacagt ccttgattct ttgaaagaag
    21541 caggaaagga cgtgattgct gttggaaaga tcaacgatat tttcaacgga caaggaatca
    21601 ctgaatctgt ccgcacgaaa agcaatatgg atggcgttga ccagctgctg aaagttatga
    21661 aaaacgattt ttcaggaatc agctttacca atttagtaga ttttgatgca ttatacggtc
    21721 atcgtcggga tgtagtcggc tatgcgcatg cgattgaaga atttgactta cgaattccag
    21781 aattgcttga agcgatggaa gaagacgact tgctaatgat tacagccgat cacggaaacg
    21841 atccgacgtt tactggtacc gatcatacgc gagaatatgt accgttattg gtttacagta
    21901 aaaaaatgaa agaacaaggg gcattgcctc aaggatatta ttcagatatt tcagcaacga
    21961 ttgctgagaa ctttagtgtt tcttcgactg aaaatggcga aagcttcttg aaattattaa
    22021 aataatcttt ttaaatagga gaaagcaaat gaccaagtta agcgagatgt tacaagaaac
    22081 gacccagttt atccttgata aaggagtaaa agaaattgat tttggtttga ttctaggttc
    22141 aggattaggt gaattagcag atgaaatcga agatgctgta atgatttctt atgatgagat
    22201 cccgttcttt cctgtttcga cagtagttgg gcatgcagga aagctagttt atgggtctct
    22261 ggcaggcaag aaagtgttag ccatgcaagg gagattccac tactatgaag gtcattccat
    22321 gcaaacagtg acctatccag tacgtgtgat ggccggacta ggggcccatt cagtcattgt
    22381 gactaatgca tgtggtggtg tcaacgaatc atttgtacca ggagatttga tgctgattac
    22441 cgatcatatc aattttactg gtgaaaatcc tttgatcggt ccgaatgaag atgcaatggg
    22501 ccctagattt ccagatatga gtcaagctta tacgcctgac tatcaagcaa cagcaaaagc
    22561 agcagcagaa aaactaggtt tggatcttaa agaaggcgta tatatgggct attctggacc
    22621 aacttatgaa acgcctgcgg agatccgaat gtctcggaca ataggagccg atgcagtagg
    22681 gatgtcgact gttccagaag tcatcgtagc agctcacagc ggattaaaag tgttaggaat
    22741 ctcttgtatt accaacttag cagcaggtat gcaagcgaat ctgagccatg aagaagttgt
    22801 agaaacaact cagagagtca aacaatcttt taaagcattg gttaaagaaa cattgacatt
    22861 attgtaatag gaggaacaat aaaatgagtg tgcatattga agcgaaagaa ggcgagatcg
    22921 ccgataagat tttacttccg ggagatcctt tgcgagctaa atatattgcg gagacttttt
    22981 tggaagatcc agtttgttac aatcaggtac gcggtatgtt aggctttacc ggcaaatata
    23041 aaggagaacg tatttctgtt caaggaacag gaatgggaat gccatcagcc accatctatg
    23101 cccatgaatt gatccagtcg tatggtgtaa agaaattgat tcgagtaggt acatgcggtg
    23161 cattgtcaaa agacgtccat gttcgtgatt tagtactagc acaaggtgca gcgaccagtt
    23221 cttcgatgat cgaaaaaaat ttccaagcct ttcattttcc tccaatcagt gatttcaatc
    23281 tattactgaa agcatatgag atagctaaag aaaagggcta tacggttcat gtaggaaatg
    23341 ttctttcgga agattctttc tacaaagatg atttgacaga gacgttccaa ttagctgaac
    23401 ttggcgtttt aggagtggaa atggaagcag cggctcttta ttacttaggc gcgaaatacc
    23461 atgtgcagac attaagtttg atgaccgtta gcgaccattt gatcaccggt gaagaaacaa
    23521 cagctgcaga acgtcaatct acgttcaatg aaatgatcga agtaggattg gaaacagcga
    23581 tagcagaata agaaggaaat gaaaaagctg ccctgcatta agtaataaga acatccaagc
    23641 aaaaatagct cctcatgttt ttgacttggc tggacttatt attgcaaatg taagcttttg
    23701 aacaccgttt accaagaggt tgtgaatctg ccgtttaact ctgagtcaca aggaacaatt
    23761 tcaaaaa
//
LOCUS       DAIGTA010000239        21096 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.053, whole genome shotgun sequence.
ACCESSION   DAIGTA010000239 DAIGTA010000000
VERSION     DAIGTA010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.053"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            62..1981
                     /gene="tet(M)"
                     /locus_tag="NOB43_002953"
     CDS             62..1981
                     /gene="tet(M)"
                     /locus_tag="NOB43_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCI0983710.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSMEIIIKQKVEL
                     HPNMCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            2079..2267
                     /locus_tag="NOB43_002954"
     CDS             2079..2267
                     /locus_tag="NOB43_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI0983711.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(2325..2678)
                     /locus_tag="NOB43_002955"
     CDS             complement(2325..2678)
                     /locus_tag="NOB43_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983712.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            3209..3631
                     /locus_tag="NOB43_002956"
     CDS             3209..3631
                     /locus_tag="NOB43_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0983713.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            3628..3858
                     /locus_tag="NOB43_002957"
     CDS             3628..3858
                     /locus_tag="NOB43_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983714.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            4356..4556
                     /locus_tag="NOB43_002958"
     CDS             4356..4556
                     /locus_tag="NOB43_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI0983715.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            4583..5776
                     /locus_tag="NOB43_002959"
     CDS             4583..5776
                     /locus_tag="NOB43_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0983716.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(5844..7409)
                     /gene="guaA"
                     /locus_tag="NOB43_002960"
     CDS             complement(5844..7409)
                     /gene="guaA"
                     /locus_tag="NOB43_002960"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI0983717.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(7468..8391)
                     /locus_tag="NOB43_002961"
     CDS             complement(7468..8391)
                     /locus_tag="NOB43_002961"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI0983718.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            8587..9192
                     /locus_tag="NOB43_002962"
     CDS             8587..9192
                     /locus_tag="NOB43_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0983719.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            9500..10516
                     /locus_tag="NOB43_002963"
     CDS             9500..10516
                     /locus_tag="NOB43_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0983720.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            10657..11958
                     /locus_tag="NOB43_002964"
     CDS             10657..11958
                     /locus_tag="NOB43_002964"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCI0983721.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            12004..12666
                     /gene="deoC"
                     /locus_tag="NOB43_002965"
     CDS             12004..12666
                     /gene="deoC"
                     /locus_tag="NOB43_002965"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCI0983722.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            12687..13085
                     /locus_tag="NOB43_002966"
     CDS             12687..13085
                     /locus_tag="NOB43_002966"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCI0983723.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            13151..14233
                     /locus_tag="NOB43_002967"
     CDS             13151..14233
                     /locus_tag="NOB43_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0983724.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            14445..16007
                     /locus_tag="NOB43_002968"
     CDS             14445..16007
                     /locus_tag="NOB43_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983725.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            16000..17133
                     /locus_tag="NOB43_002969"
     CDS             16000..17133
                     /locus_tag="NOB43_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983726.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            17133..18089
                     /locus_tag="NOB43_002970"
     CDS             17133..18089
                     /locus_tag="NOB43_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0983727.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            18188..19354
                     /gene="deoB"
                     /locus_tag="NOB43_002971"
     CDS             18188..19354
                     /gene="deoB"
                     /locus_tag="NOB43_002971"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCI0983728.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            19378..20196
                     /locus_tag="NOB43_002972"
     CDS             19378..20196
                     /locus_tag="NOB43_002972"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0983729.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            20213..20920
                     /gene="deoD"
                     /locus_tag="NOB43_002973"
     CDS             20213..20920
                     /gene="deoD"
                     /locus_tag="NOB43_002973"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0983730.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         6788 a         3762 c         4533 g         6013 t
ORIGIN      
        1 taaaagtatt tatcactggg atttttatgc ccttttgggt ttttgaatgg aggaaaatca
       61 catgaaaatt attaatattg gagttttagc tcatgttgat gcaggaaaaa ctaccttaac
      121 agaaagctta ttatataaca gtggagcgat tacagaatta ggaagcgtgg acaaaggtac
      181 aacgaggacg gataatacgc ttttagaacg tcagagagga attacaattc agacaggaat
      241 aacctctttt cagtgggaaa atacgaaggt gaacatcata gacacgccag gacatatgga
      301 tttcttagca gaagtatatc gttcattatc agttttagat ggggcaattc tactgatttc
      361 tgcaaaagat ggcgtacaag cacaaactcg tatattattt catgcactta ggaaaatggg
      421 gattcccaca atctttttta tcaataagat tgaccaaaat ggaattgatt tatcaacggt
      481 ttatcaggat attaaagaga aactttctat ggaaattata atcaaacaga aagtagagct
      541 gcaccctaat atgtgtgtga tgagctgtac ggaacctgag caatgggatg tggtaataga
      601 aggaaatgat gaccttttag agaaatatat gtccggtaaa tcattagaag cattagaact
      661 cgaacaagag gaaatcagaa gatttcagaa ttgctccttg taccctgttt atcatggaag
      721 cgcaaaaagc aacataggga ttgagcagct tatagaagtg ataacgaata aattttattc
      781 atcaacatac agaaagaagt ctgaactttg cggaaatgtc ttcaaaattg aatattcgga
      841 agaaagacaa cgtcttgcat atgtacgcct ttatggcgga atcctgcatt tgcgggattc
      901 ggttagaata tcggaaaagg aaaaaataaa aattacagaa atgtatactt caataaatgg
      961 tgaattatgt aaaattgata aggcttattc cggggaaatt gttattttgc aaaatgagtt
     1021 tttgaagcta aatagtgttc ttggagatac aaagctattg ccacagagag agagaattga
     1081 aaatccgctc cctctgctgc aaacaactgt tgaaccgagc aaacctcaac aaagggaaat
     1141 gttacttgat gcacttttag aaatctccga cagtgacccg cttctacaat attatgtgga
     1201 ttctacgaca catgaaatta tactttcttt cttagggaaa gtacaaatgg aagtgattag
     1261 tgcactgttg caagaaaagt atcatgtgga gatagaacta aaagagccta cagtcattta
     1321 tatggagaga ccgttaaaaa atgcagaata taccattcac atcgaagtgc cgccaaatcc
     1381 tttctgggct tccattggtt tatctgtatc accgcttccg ttgggaagtg gaatgcagta
     1441 tgagagctcg gtttctcttg gatacttaaa tcaatcattt caaaatgcag ttatggaagg
     1501 gatacgctat ggttgcgaac aaggattata tggttggaat gtgacggatt gtaaaatctg
     1561 ttttaagtac ggtttatact atagccctgt tagtactcca gcagattttc ggatgcttac
     1621 tcctattgta ctggagcaag cctttagaaa agctggaaca gaattgttag agccatatct
     1681 tagttttaaa gtttatgcac cacaggaata tctttcacgg gcatataacg atgctcccaa
     1741 atattgtgca aatatcgtaa atactcaact gaaaaataat gaggtcatta ttattggaga
     1801 aattcctgct cgatgtattc aagattatcg caatgattta acttttttta caaatgggct
     1861 tagtgtttgt ttagcagagc taaaaggata tcaggttacc actggcgaac ctgtttgcca
     1921 gacccgtcgt ctaaatagtc ggatagataa agtaagatat atgttcaata aaataactta
     1981 gtgcgtttta tgttgttata taaatatggt ttcttattaa ataagatgaa atattcttta
     2041 atatagattt gaattaaagt ggaaaggagg agattgttat tataaactac aagtggatat
     2101 tgtgtcctat ttgtggaaat aaaacaagac tacgaatacg agtggatact atacttaaaa
     2161 atttcccttt atactgcccc aaatgtaaga acgaaacttt aattaatgtt caaaaaatga
     2221 atataataac aatcaaagag ccagacgcca agacgcagag ccgataattt gagaaatgaa
     2281 actctcatct tatcggctct ttttgtttat ctgaatttta ctgactagcc ttcaatattt
     2341 cttgcttcat tgataccttt tgctagtgct tccattaagg atagttcttt gtctgtaaag
     2401 ctatccatgt atttttctac ctgtaacctt cgagtgcttt taatcaaatt atctgtaggt
     2461 aagaaaaatt catcaataga tacatggagt aatgatacaa gatcatacag cacttgtgta
     2521 cttgggtgtt gtcctttgtt ttctatattt gttaaataac gtgggtcaat ttcaatcatt
     2581 gttcccactt gttcacgagt gagaccccgt ttcattcgag cctctttaat cgctaaacca
     2641 acggctctaa aatcgtattt atcttctttt ttacgcatac taaatcacct ctatacattt
     2701 tactgttcct atataaccat aaacaggtat agaaaaacat gttatatagt ttatgagttc
     2761 ctatagaaca ctgtggaatt tattaatgcg atgaatccaa tttcaaatag aaaggtcgct
     2821 gattttattt acctatacaa ctttataaaa tttagtcata ctcctagaaa gtagataaaa
     2881 ttggcgactt aatggaggga aaagtcgcca tgagaaagat aatctgtcat ctagttctct
     2941 taattaagtt cttatcaaaa aaacttatcc acctgtactg gatagatatg accatcaatg
     3001 tggttttgca gattacatag atagaaaaat caaagcatat gaacagagaa aacaatctgt
     3061 ttatgtgctt ttttggtcac ttaataaata tcttttagga tttctcttca tttatgcaac
     3121 aaatcccccg ttcgtgtcgg ggtttagtat gaagggagat aaagaagcac atgccactcc
     3181 ctttcacgac agaaaggggg tgaaaagcat gaaaccatct tcttttcaag aaaccataga
     3241 aaatcagttt gactatatct gcaaacaagt tattgaagat gaacgaaaag attacttcaa
     3301 acatctagac agactatcag caaaagaagt ctcgttttct gatatagata actaccttgt
     3361 caactctttt tctactgttg atacgtacgt cactgatttc caactattta aattatttgg
     3421 attaagaatc aatgttgaaa gtgatttatt aagtgaagcc ctgcgtcatc tttcagagaa
     3481 aaaacggaac attattttac ttcattactt tatggatatg agtgatgtgg agattgcgga
     3541 gttactaaat ttgaatcgtt cgactgttta tcgtcatcga ataagtggac tagccatgat
     3601 taaagaattc atgaaggagt gtaaagaatg aaaacagctt atccaagggt tcccttcccc
     3661 ctcattgtaa aggcgacaga tggcgacgtg gaagcaatta atcagattgt taaacattat
     3721 cgagggtata cctcaaaacg ttcattacgt cgcatgacag acgaatatgg aaattctcat
     3781 atggttattg atgaaaccct acgtggcaga atggaaacga aactcatctc taagatttta
     3841 tcgttcgaaa ttaaatagtc ccattttttc gtggaagcgt gtcgaatcgt atccacgctt
     3901 cccgatttgg gaggtttgtt attccatcaa agcatattgt gtgttcagta ggttttgata
     3961 ggctaacaag ccaaacgttc tttgacaacc aaataaaggc aatcgaatac gtttcggtaa
     4021 gaaaagagct gatgaactaa cacgccatga cctacaaaat tagtgagcga ttcatgttag
     4081 taattcgaaa gtaatcttta gcaggattgc tgccatgact ttcttatcgt gataatgata
     4141 ctcccgtata gccatagtcc gagcgttaga agcgtcacag gcaatgggta cggctacatg
     4201 agaaccatgc agaagtgaaa ttcctgtgag ctttgctaga gctgttcgat tgctaagata
     4261 ttcttctctt gtcagtgtat tattataaaa ctatttgata taattatagg tgaatattgg
     4321 agttttccta gcctataatt gggaaaggag taataatgat aacggtcaca aaaaaggatt
     4381 tagttgagct aggatatgga acttcttttt cagcagacat cataaaaaaa gcaaaagaat
     4441 tgatgattac aaaagggcat atctactatc aatctcgaaa gctagataga gtccctcgtg
     4501 aagctgttga agaaattcta ggaattcggt tttcaaatga aaacaggtct gagtagtttt
     4561 tgcacagtaa ggagtaaaaa ctatggttaa agacccaata aaaaaagcaa agaatggaac
     4621 ctattatttt cgtgcaaatc taggttatga ttctaaaggg aaaaaaattc aaaaatatcg
     4681 tagtggattc actactaaaa aagaagcaag agaagaatat tcgaaactgc tattgatgaa
     4741 accagaagaa ttaagtgaga ataaggataa aatgacgttt aaacattata tctttgaaat
     4801 tttccttcca tggtataaga cacaggtaaa gctcagaaca tatgaaaatc gcttaccaac
     4861 tattaagaag catttctctt attttgataa aatggctgtt tccgatattg agcctattga
     4921 tgtgcaaaat tggcaactaa aattatcaaa gaagtgtaag tcttcttatg taagagctgt
     4981 tcaaggacta ttttcagttg ctatggatcg agcaattgtc cttgggataa ccaccacaaa
     5041 tccatctaag attattggca atgtgaaaaa gcaaaagtct aaaattgaat tttggacaaa
     5101 agaagaattt gaaaaagtaa tctctctaat ttacaaagaa gattactatc aacacttttt
     5161 atttatctct ctgtggtttt tatttatgac tggaatgcga attggtgaag ctactgccat
     5221 tcaatgggaa gatattgatt ttgactcagg agtactaacc atcaacaaaa cactctatta
     5281 caagaatcaa tcgaattata gatttgttga accaaaaaca aaggcgagcg ttcgtcatat
     5341 tgtattagat aaatgcacat taacttattt atccgaatgg aaggaagtac aacaaaatct
     5401 aattcagaca gactttgtaa tgagctataa cggtattcct acccaaaaac atacactatc
     5461 atatgctatt gaacgctatg ctaagctggc tggtatccat cgaatcagaa tccatgggtt
     5521 acggcattct catgcttcct tgttaatcag tatgggagaa aatccactta tcattaaaga
     5581 tcgtctagga cacgaagata ttgagacgac tttaggaacg tatggacatc tttatcctaa
     5641 cagtaatttc gaggtagcta acaaattaaa tggagccatt tcctttaaag aagcaaaaca
     5701 aaattatgat acttcaccaa agaatcaatt tactgtagac tacttgcgaa acaaagaaat
     5761 gaaaaaagtg caataaaagt gcagtaaaaa gataagaaga gccagaaacc cttggtataa
     5821 gaggatttct agctctccta caactattcc cactccactg ttgctggtgg tttagaagtg
     5881 atgtcataca cgatacggtt gacgtgggct acttcgttta cgatacgtac agagattttt
     5941 tgcaagactt cccatgggat acgggcaaag tcagcggtca ttccgtcgat tgaagttaca
     6001 gcacggatac cgactgtgta gtcgtaagta cgtccgtcac ccataacacc gacagagcgg
     6061 atccctggaa gaacagtgaa atattgccag atatcacggt caagtccagc agctgcgatt
     6121 tcttcacgca agatagcatc agattcgcgt acgatttcta gcttgtcttc agtgatttcg
     6181 ccaagaacac gaataccaag accaggacca gggaatggct gacgccaaac gattgaatca
     6241 ggcatgccta actgagtccc taattcacgg acttcgtctt tgaataatgt gtttaatggt
     6301 tcgatcaatt caaattgcat atcttctggc agtccaccta cattatggtg agatttgatc
     6361 gtctgtgctg tttctgtacc agattcgata acgtcagtat acaacgttcc ttgtgctagg
     6421 aaagagacgc cttcttcacc agcaagtttt gttgcttcgt catcaaaaac atatacgaat
     6481 tcattcccaa tgattttacg tttttgttct gggtcagata cacctttcaa cttgtctaag
     6541 aagcgatctc ttgcatcgac tttgatgatg ttcaagccga attttccgcc tagactttcc
     6601 attacttgtt ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat agatgtcaat
     6661 tggtcaccga tcgctttttg taaaagaacc ccaacgacac tagaatcaac gccacctgaa
     6721 agaccaagca agactttttt gtcaccaact tgttcacgga ttttttctac ttgcatatcg
     6781 ataaagttat ccattgtcca gttaccttca cagtgacaaa catcaaaggc aaagtggcgc
     6841 agcaattcga ttccgtattc ggaatgacgt acttctgcat ggaattggat accataaaaa
     6901 ttacgtgttg tgtcttggat agaagcaatc ggacaatctt tgcttgttcc gactgtttca
     6961 aagccttcag gaactttagt taccaagtca ccatggctca tccatactgt ttgttgtttt
     7021 ggtgtttctt taaacaagac agcttgatcg cttgttactt ctaacaaggc tttcccatat
     7081 tcgcggtttt tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa ttgcatacca
     7141 tagcaaatcc ctaatacagg aatacctaaa ttgaagatct caggatcgat cccaaatgca
     7201 ttctcatcat atacactgtt tggtccgcca gaaagaatga ttccctttgg attcatcgct
     7261 tttacttctt ctgcagtaat gcggtggctc aataattcgg aaaagactcc aagatcacga
     7321 atacgtcttg tgatcaattg gttatactga ctaccgtagt ctaatacgat aatcttttca
     7381 acgttcgtca tatcggcaac gtttgtcaaa tttattaccc ctatcccttt aaattttatc
     7441 tcaaaatagt caaactattt taaaatgcta atattttcgc atgaaaatcg aatcgatgat
     7501 atgattttca gttttatgga gaattatatc ggctcttcct cgtgtaggca agatatattc
     7561 ctgtaaattt ttcaaattca catttttcca tacatctttt gccattttaa aggcttcttc
     7621 acgatctccg atagcaaaac gataataata attctctgga ttttggaaag ccgtatccag
     7681 taacgcacca aaacgatcca aataccattt ttcgatcagc acgggatcgg catcgacata
     7741 gacagaaaaa tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta attgaagcgt
     7801 attgatcccc tcaacgatca agatatcagg ctgctggatc aattcgtact tgtctggaat
     7861 gatatcatac acatcatgtg agtaaacagg tacttttatc tcttcctgac cagattttac
     7921 acggttcaag aaatcgatca gcatctccat atcataactt tcaggaaatc ctttacggtc
     7981 catgattcca cgctctttta atatacgatt tggataaaga aatccgtcag tcgtgatcag
     8041 ctgaacgttt cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc tggctgttgt
     8101 actttttcca acggctacac ttccggcgat cccgataata aaaggcggta cttctacgta
     8161 tttatgaaga aataaacctt tactcaagaa caaagattca aattctttca tataaagata
     8221 aatcagatga gcaagaggta catagatatc tcgaacatcc tgcatggaaa tgcggtcatt
     8281 caaacttttg atattatcta gttcatcttg tgtcaaaggt gcttgcccat tacgataaaa
     8341 ttctcgccat tcttctcttg ccacacggta gtagttcatt ggatcattca tattagcctc
     8401 ctgcgttctc ccatcaatgg aactatttta acacaaaata aacgcaaacc ccaccactta
     8461 agagagattg ccgatctttt tgtataatct ttataataga aagaaacgga gtcttattct
     8521 tgacttgcgc acggatacat aaaaggatag actgttgtca tgaaagaaat gagaaggatg
     8581 gaagacatga caaatcatta ctattctgaa cgcccagata cggcgcacga ttttgaacaa
     8641 tgggcttttg agttaaaagg cagaaccttt caatttgtaa cagattctgg tgtattttca
     8701 cgtgaaacag tggattatgg ttcacgtgtc ctgattgatg ctttcgattg ggaagagtta
     8761 cctgatgaag gaaagatctt agatgtggga tgcgggtatg gaccgattgg gttagctttg
     8821 gcatttgcga cacagcggtt tgttgaaatg gtcgacatta atgaacgagc ggtaagtcta
     8881 gcgcaaggaa acgcaaagcg taaccaaatc gaacatgttg atatccatca atcgaatatc
     8941 tatgaagcag ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc gatccgtgct
     9001 ggaaaaaaag ttgtacatga aattttgaca ggcgcatatc ctcggttgaa gaagggcggt
     9061 acactgacaa ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa gaaaatggaa
     9121 gaaacatttg gtaatgcaga aatcgtcaca aaagataaag gatattatat catcaaaagt
     9181 gtgaaagaat aactagctga aaaatagtgg agcgacgaaa gagtggaact gggcgtgcat
     9241 gtacgggtac gtatcagttc tttttttgtt gagaagtttt taaaaacaaa gaactatttt
     9301 ttcttcaaaa agaaatagta ggaacagagt cgttgttttt tacgataaaa taaataagat
     9361 acagaacttg tatagaaggc tgccaagtcg gtagataaag gaggttttta tcaaaaaaca
     9421 tactttcctt ttttctctat tcttttcttg ggggttttgg tacactgata gggaatttag
     9481 atagaaggga gccaatagga tgaagctgac catcagagat atcgcagaaa tggcaggcgt
     9541 atcagtaaca actgtctcac agattttgaa taacaaagga agcagattta gtgataagac
     9601 aagaaaaaaa gtgttgtcga tcgtgaatga acatcattat aagcccgatt atttcgcttc
     9661 aaatgtgatc aatcgacatt caaagaccat cggaatgatc gtccctgatg tcactgattt
     9721 cttcttctcc aaactgatcg aaggtgtaga gagctatttg aatcctttgg gctatgtgat
     9781 catgttatgc aattctcgtc atagccaaga aaatgagatc aagtatttac aagagctttc
     9841 ccaccgctca gtggacggaa tcttgctggc cacaccaaat attttacctg agaaatatgc
     9901 attagacagc ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg gattgaatcg
     9961 tcgggataac ggacggctta tcgtaaagga atatgagggc gcctatcaag ctgtttcgct
    10021 gtttattgaa aatggccata cgaagatcgg catgctgaag gaaaccactg gatactatca
    10081 attagaagaa cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc tgccttttaa
    10141 tgggaaattt gttgaacatg gagagttgac tgtccaaggt ggatatactg catcaaaaaa
    10201 attactcaaa cataaagata tcacggctat tttttgcggg aatgatgcca tggcgatcgg
    10261 atgctatcag gcgatcgatg aattgggcaa aaaaatccca gaagatatct cagtcatagg
    10321 attcgatgga ttaaagctgt cagaatacat gattccgcaa ttgacgacag tgcagcagcc
    10381 aagttttgat attggatttt atgctgcacg tttcctgatc gatacgatcg aatttcctca
    10441 aagaaaagtt ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga gcgtaaaagt
    10501 attgacaaag ggctaactcg gcggtatatt gcttatgtaa gcatttacaa aggctagtta
    10561 gtgctttttt tatttttagt aaaccagttt actaaagtgg tttacctttc ctaaaaataa
    10621 tgtataatac cgaatgaaga caaggaggat caggcaatgc gaatggtgga tctgattgaa
    10681 aaaaagaggg atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt cacgaactat
    10741 acgaatggaa agattccaga ttatcaagtc agtgcattat tgatggcaat tttttatcaa
    10801 gacatgacaa atgaagaaat cacgaactta acattggcga ttgctaattc tggtgatgtc
    10861 atcgatttga gttctcttga aggaataaag gtagataagc attcgacagg tggcgttggt
    10921 gacacgacca cattgatttt agccccccta gtagctagtg tcggagtgac agtggctaaa
    10981 atgtctggac gcggtctagg ttacacaggt ggtacactag acaagctaga agcaattccc
    11041 ggatttcaga tcgagctttc ggatgaagaa tttgtacgca ttgttaatga aagtaaagta
    11101 gcggtaattg gtcaatcagg aaacttggca ccggcggaca aaaaattgta tgccttgcgt
    11161 gacgtcacag cgaccgttga ttctcttccg ctgattgcca gttcgattat gagtaaaaaa
    11221 atcgcggcag gagcagatgc aatcgttttg gatgtgacca ctggagacgg tgctttcatg
    11281 aagaacatcg aagatgcaag acgtctggca aagaccatga cgagcattgg gaaactggct
    11341 aaccgagaaa cagtggcggt tatctcagat atgtcagaac ctcttggcga agctatcgga
    11401 aatagtctag aagttgtcga ggcaatcgaa acattacaag gaaatggtcc agaagatcta
    11461 gtagaaatgt gctacgcctt aggaagccaa atggttgttc ttgctggcaa agctaagaca
    11521 accgatgaag caagaacgtt gcttcaagaa gctctggaat caggtaaagc gttagcaaaa
    11581 ttcaaagaaa tgatccaaaa tcaaggggga gacccagcga tcgtggaaca tccagaacga
    11641 attttgactg cacgctacac aatggagctt cctgctaaac aaagcggagt tgtgtcaaaa
    11701 atcgtggcaa atgaattagg aattgctgca atgatgctag gtgctgggcg taaaaccaaa
    11761 gaagaagata ttgatcacgc tgttggattg aaactgcata aaaaaattgg tgacactgtg
    11821 acaaaaggtg agtcactatt gacgatctat agtaacgacg aagaaatcac ttctgtcatt
    11881 gaattattat ataaaaatat tgaaattggt gaatcggcaa tgaagccaac gttgattcat
    11941 gacatcatca cagaataaag gaaaaaagcg gactttaccg ttttaaagaa aaggggaaaa
    12001 gaaatggaac taaaccgaat gatcgaccat actattttga aagcagacgc atctaaagaa
    12061 gctgtgatgc aaattatcga agaagcaaaa aaataccatt tttattctgt ctgcatcaat
    12121 ccagcatggg ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc cgtatgtaca
    12181 gtaatcgggt ttcctctagg agcaaacaca cccgagacaa aagcatttga aacaacagat
    12241 gccatcaata acggtgcaga tgaagtcgat atggtcatca atatcggtgc tttgaaatca
    12301 aaggatgatc aacaagtcca aaaagatatc gaagcagttg ttgaagcagc aaaagatcgt
    12361 gcgcttgtca aagttattat tgaaacatcg ttattagata gagaagaaat catccgagct
    12421 tgcgaaatag caaaagctgc aggcgctgat tttgtcaaaa catcaactgg tttctcaaca
    12481 ggcggagcaa aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc agaaatgggt
    12541 gtcaaagctt ccggcggtat ccataacgaa gaagaagcaa tggcaatgat cgaagctggt
    12601 gctacaagaa tcggaacaag cgcaggagta gcaatcgtat ctggttcaac tggtgaaggc
    12661 tattaatttt ttcaaaggag aagctcatgg cagaactcaa acaagaatgg atcaacacag
    12721 ctattgaagc gttagataaa gcctatgttc cttattccca ttttccggta ggcgcttgtc
    12781 tcgtaacgga atcaggcaag atttatcaag gcatcaacat tgagaatgca tcatttggat
    12841 taacgaattg tgccgagcgc acagcttttt tcaaagcagt atctgaagga gaaaaaacat
    12901 ttacgcatct agtcgtagcg gggcacaccc ccgatcctat ctctccttgt ggtgcatgtc
    12961 gacaagtaat ggcagaattc tgttcccctg atatgccggt tacgctagta ggagacaatg
    13021 gtgtgacgaa ggcaacgacc gttcgtgcac tgctgcctta tgcatttact gaaaaagatc
    13081 tataactcat gttcattcag tcagctgact gttgaaaaat aaaacaatta ttttaggagg
    13141 ctttacagaa atgaaaaaag caaaattatt tggtttaggt gctgtcgcac tagcagcagg
    13201 gttattttta ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg gcaaaagctc
    13261 atcagacaca acaactgcag cattgatcac agacacaggt ggtgtagacg accgttcatt
    13321 caaccagtca gcttgggaag gactagaaaa atgggggaaa gatcaaggac tttcacgagg
    13381 aaatgatggc ttccaatatt tccaatcttc aaatgaatca gattacatcc caaatattga
    13441 ccaagcattg aatgctggat tcaaaacgat ttttggtatt ggttataaac taaaaccagc
    13501 gatccaagaa caagcaacaa acaatacagg tacgaacttt gttattatcg atgatgtcat
    13561 cgatggatta gataacgttg tatctgcaac tttcaaagac aacgaagctt cttatcttgc
    13621 aggtgttgca gcagcttata cgactgaaac aaacgtagtc ggctttatcg gcggtgtaaa
    13681 aggtgaagta atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg caggtgcgaa
    13741 agaattagga aaagaaatca aagtattgaa tcaatatgct ggtgacttct ctgctccaga
    13801 taaaggacgt tcaattgctc aaggtatgta tgcacaaaac gcagatatca tcttccatgc
    13861 ttcaggcggt acaggtaacg gtgtattcca agaagcaaaa tcattgaacg aatcaggcga
    13921 caaaaaagtt tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg aatacacatt
    13981 aaacggcgaa aagaaaaact tcacattgac atctacactg aaagcagttg gaacagtagt
    14041 agaagatttg gcacaaaaat cagcggacgg taaattccct ggcggcgaac acactgttta
    14101 tggattgaaa gaagacggtg ttggtctaac agaaggacaa ctttctgacg aagcgaaaaa
    14161 agcagttgat gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc cagaaactcc
    14221 tgaagaaaac taaaaccatt tctatagcct tgttagacac atgtttgaca aggctatggt
    14281 ttgattagaa caagaattgt tcatttatcc aagctgcctt gtgacagttt ggataaggga
    14341 acaactccct gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg tgaatcttag
    14401 tcaatcgttg ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt caagaaaata
    14461 ttgtcataga aatgcagaat attaccaaag aatttggaac attcaaggca aatgacaaca
    14521 tcaatttaca agtaaaggca ggagaaattc atgcgttgct tggagaaaac ggtgctggca
    14581 aatctacatt gatgaacgtg ctttccggat tattagagcc gacatcaggg aaaattttga
    14641 tgcgtgggaa agaagtaaag atcacaagtc cgaccaaagc caaccaatta gggattggga
    14701 tggtccatca gcactttatg cttgttgatg cctttactgt aacagaaaac atcgtgttgg
    14761 gaagcgagcc tagtcgcgca gggatgcttg accataaaaa agcacgaaaa gagatccaaa
    14821 aagtttctga acagtatgga ttgtcagtca acccagatgc ttacgttcgt gatatttcag
    14881 ttggaatgga acaacgggta gaaattttaa aaacacttta ccgaggagca gatgtactga
    14941 tttttgatga gccgacagct gtattgaccc ctcaagaaat tgatgaatta atcgtgatca
    15001 tgaaggaatt agtcaaagaa ggcaagtcga tcattttgat tacgcataag ttagatgaaa
    15061 tcaaagcagt agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc ggtacagtca
    15121 acgttaaaga cgtaacctca caacaattag ccgatatgat ggttggaaga acggtttcat
    15181 tcaaaacgat gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt gaaaatctag
    15241 tggtgaaaga aaatcgtgga ttagaagccg tgaaaaactt gaacttagag gttcgtgctg
    15301 gcgaagtact tggtatcgct ggaatcgatg gaaacgggca gtcggagttg atccaagctt
    15361 tgactggttt gcgaaaggca gaaagcggac atatcaagct aaaaggggaa gacatcacta
    15421 ataaaaaacc ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa gaccgtcata
    15481 aatacgggtt agtcctagat atgacattat ctgaaaatat cgcactacaa acctatcatc
    15541 aaaaacctta cagtaaaaac ggcatgctga attattcagt aatgaatgaa catgccagag
    15601 aattgatcga agaatatgat gttcgaacaa cgaatgaact tgttcccgca aaagctttat
    15661 caggcggaaa tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat cctgatctgt
    15721 tgattgttgc aaatccaact cgtggactgg atgtaggtgc gatcgaattt attcataaac
    15781 gtctgatcga acaaagggac aaatacaaag cagtgttact gatcagtttc gaattagaag
    15841 aaattttaaa tgtttcggat cgtattgctg ttatccatga aggagaaatt gtcggtatcg
    15901 ttgatccgaa agaaacatct gaaaatgaat taggtctatt gatggcgggc tataccttag
    15961 aagaagcacg aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg cagcgaaaaa
    16021 ttccgtaatt tattagtgcc tgtactttca gttgttttag gattgatctt aggcgcgata
    16081 ttgatggctg cttttggttt tcagcccatc caaggttatt cttctatgct agatgcagcc
    16141 cttggttcgc aaagagggat aggtgaaacg ttaaggcaag caacgccgtt gatttttaca
    16201 gcattaggtt tttctgtagc taactcagct gggtttttca atattgggct ttctggacaa
    16261 gcactttgcg ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga tctgccaaaa
    16321 gttgttttgc ttccgttatg cgtgatctta ggtgccttag ctggtgcgat ggcagcggct
    16381 gttccaggtt tacttcgagc attttttgga acaagtgaag tgatcgtaac aatcatgatg
    16441 aactatatct tattatacgt aagcacattt gctttacatg aagtgatgcc tgaaagctat
    16501 cgctcaagtt tggactcttc caatatgatc agtcaaaatg cctcactgcg gttaccatgg
    16561 ttaacacaag cttttggcgg ctctcgcgta aactcaggat tatttttagc aatcatcgcg
    16621 cttattttcg tttggctgct gatgaagaaa acgactttag gatttgaaat ccgttctgtt
    16681 ggattgaatc cttttgcttc tgagtatgca ggaatgagta gtaaacgtac gatcgttttg
    16741 tcgatggtca tttctggcgc tttggcaggg cttggcggtg tggttgaagg attaggaacg
    16801 tatcaaaact tctttgttca aacgacttcg ctatctattg gatttgacgg aatggctgtt
    16861 tccttgcttg gttctggatc agcaatcggt attcttttat cagcgatctt gttcagtatt
    16921 ttgaagatcg gtggacttgg catgcagaca ggagcaggtg ttccgtttga gatcgtcaat
    16981 gtatcgattg ctttgattat cttctttgtc gggatcaact tcctgattcg tttcgtcatg
    17041 gctaaagtct tccaagggaa aaaacaagaa gagatcgttg cgacaataga atcgaaacca
    17101 acgaatcaaa accatgaagg gggcgaacta taatgtcgac tatcgaatta attgccttga
    17161 tccttacttc tacactggtt tattcaacac cgctaattct aacgtcacta ggcggaactt
    17221 tttctgaacg aagcgggatc gtaaacgtag ggctagaggg aatcatggtc atgggtgctt
    17281 ttagttccat cgttttcaac ttgacgatga gtccatcact tggttctatg acaccatgga
    17341 tcgctatttt agtgggtggc gtcgtaggta tcctattttc tctgattcac gcagtagcaa
    17401 cagtcagttt gcgtgctgac catattatca gcgggacagt aattaatctg atggcacctg
    17461 ctttaggtgt tttcttgatc aaagcatggt atggtaaagg tcaaactgat aacatcacgc
    17521 agaatctggg gtatttttct ttcccaggat tagcagatat tccggtcatt ggaccaattt
    17581 tctttaaaaa tacattctta cctgcttatt gtgctatttt gattgctgtc ctagcttggg
    17641 tgatcatctt caagacgaaa ttcggcttgc gcctccgttc agttggtgaa aatcctcaag
    17701 ctgccgacac attaggtatc aatgtatatg ctatgcgtta ttcaggcgta ctgatttctg
    17761 gcttgttagg cggtatgggc ggtgctgttt ttgctcagtc gatttccggt aacttttcag
    17821 ctggtacgat cgttggacaa gggttcatct ccatggctgc tatgatcttt ggtaagtgga
    17881 atcctttagg ggcaatgggt gcctcattgt tctttggttt tgctcaaagc ttgagtatca
    17941 ttggcgcaca attaccagtt atttcttcga ttccgccagt attgctgcaa attgctccat
    18001 atttgctgac aatcattgtg ctggttgttt tcttagggaa agcttctggt ccaaaagcaa
    18061 acgggaagaa ctatatcaaa tcaaaataat cttttagcga ataaaaaggg tgggttacgg
    18121 gaagtgtttt tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa agaaagaagg
    18181 aataatcatg tttaaacgcg tacatctgat cgtcatggat tcagtaggaa ttggagaagc
    18241 accagatgcc gataagttcg gtgatgttgg ttctgataca ttaggacaca ttgcgaaaga
    18301 agcaggattg aacgttccac atttagagca gcttggttta ggaacgatcc gtcctcttga
    18361 aggtgtggaa tcagtgaaag atcatcaagg ctatgcgacg aaattagaag aagtttctgt
    18421 agggaaagat acgatgacag gccactggga aatcatggga ttgaatatca aaactccatt
    18481 tcgtgtgttt cctaatggat tccctgatga tctgatcaaa caaatcgaag aattttctgg
    18541 ccgtaaagtc gtatgtaaca aaccttatag cggaacagct gttattgacg attacggtga
    18601 acaccaaatg aaaacaggcg atttaattgt atatacttct gccgatcctg tccttcagat
    18661 cgcggcacat gaagaaatca ttcctttaga agaattatat cggatttgcc aattcgttcg
    18721 tgatataaca aaagatgatc cgtatatgat tggccgaatc attgcacgtc cgtacgtggg
    18781 tgaaccagga gacttcacac gaacaagcaa tcgccatgat tatgcgttga atccattcgg
    18841 acacacagtc cttgattctt tgaaagaagc aggaaaggac gtgattgctg ttggaaagat
    18901 caacgatatt ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa gcaatatgga
    18961 tggcgttgac cagctgctga aagttatgaa aaacgatttt tcaggaatca gctttaccaa
    19021 tttagtagat tttgatgcat tatacggtca tcgtcgggat gtagtcggct atgcgcatgc
    19081 gattgaagaa tttgacttac gaattccaga attgcttgaa gcgatggaag aagacgactt
    19141 gctaatgatt acagccgatc acggaaacga tccgacgttt actggtaccg atcatacgcg
    19201 agaatatgta ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg cattgcctca
    19261 aggatattat tcagatattt cagcaacgat tgctgagaac tttagtgttt cttcgactga
    19321 aaatggcgaa agcttcttga aattattaaa ataatctttt taaataggag aaagcaaatg
    19381 accaagttaa gcgagatgtt acaagaaacg acccagttta tccttgataa aggagtaaaa
    19441 gaaattgatt ttggtttgat tctaggttca ggattaggtg aattagcaga tgaaatcgaa
    19501 gatgctgtaa tgatttctta tgatgagatc ccgttctttc ctgtttcgac agtagttggg
    19561 catgcaggaa agctagttta tgggtctctg gcaggcaaga aagtgttagc catgcaaggg
    19621 agattccact actatgaagg tcattccatg caaacagtga cctatccagt acgtgtgatg
    19681 gccggactag gggcccattc agtcattgtg actaatgcat gtggtggtgt caacgaatca
    19741 tttgtaccag gagatttgat gctgattacc gatcatatca attttactgg tgaaaatcct
    19801 ttgatcggtc cgaatgaaga tgcaatgggc cctagatttc cagatatgag tcaagcttat
    19861 acgcctgact atcaagcaac agcaaaagca gcagcagaaa aactaggttt ggatcttaaa
    19921 gaaggcgtat atatgggcta ttctggacca acttatgaaa cgcctgcgga gatccgaatg
    19981 tctcggacaa taggagccga tgcagtaggg atgtcgactg ttccagaagt catcgtagca
    20041 gctcacagcg gattaaaagt gttaggaatc tcttgtatta ccaacttagc agcaggtatg
    20101 caagcgaatc tgagccatga agaagttgta gaaacaactc agagagtcaa acaatctttt
    20161 aaagcattgg ttaaagaaac attgacatta ttgtaatagg aggaacaata aaatgagtgt
    20221 gcatattgaa gcgaaagaag gcgagatcgc cgataagatt ttacttccgg gagatccttt
    20281 gcgagctaaa tatattgcgg agactttttt ggaagatcca gtttgttaca atcaggtacg
    20341 cggtatgtta ggctttaccg gcaaatataa aggagaacgt atttctgttc aaggaacagg
    20401 aatgggaatg ccatcagcca ccatctatgc ccatgaattg atccagtcgt atggtgtaaa
    20461 gaaattgatt cgagtaggta catgcggtgc attgtcaaaa gacgtccatg ttcgtgattt
    20521 agtactagca caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt tccaagcctt
    20581 tcattttcct ccaatcagtg atttcaatct attactgaaa gcatatgaga tagctaaaga
    20641 aaagggctat acggttcatg taggaaatgt tctttcggaa gattctttct acaaagatga
    20701 tttgacagag acgttccaat tagctgaact tggcgtttta ggagtggaaa tggaagcagc
    20761 ggctctttat tacttaggcg cgaaatacca tgtgcagaca ttaagtttga tgaccgttag
    20821 cgaccatttg atcaccggtg aagaaacaac agctgcagaa cgtcaatcta cgttcaatga
    20881 aatgatcgaa gtaggattgg aaacagcgat agcagaataa gaaggaaatg aaaaagctgc
    20941 cctgcattaa gtaataagaa catccaagca aaaatagctc ctcatgtttt tgacttggct
    21001 ggacttatta ttgcaaatgt aagcttttga acaccgttta ccaagaggtt gtgaatctgc
    21061 cgtttaactc tgagtcacaa ggaacaattt caaaaa
//
LOCUS       DAIGTA010000240        20862 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.054, whole genome shotgun sequence.
ACCESSION   DAIGTA010000240 DAIGTA010000000
VERSION     DAIGTA010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.054"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            267..1304
                     /locus_tag="NOB43_002974"
     CDS             267..1304
                     /locus_tag="NOB43_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0983731.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="NOB43_002975"
     CDS             complement(1393..1716)
                     /locus_tag="NOB43_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI0983732.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="NOB43_002976"
     CDS             complement(1703..2410)
                     /locus_tag="NOB43_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI0983733.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="NOB43_002977"
     CDS             2496..2837
                     /locus_tag="NOB43_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCI0983734.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="NOB43_002978"
     CDS             complement(3008..3856)
                     /locus_tag="NOB43_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983735.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="NOB43_002979"
     CDS             4454..5317
                     /locus_tag="NOB43_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0983736.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="NOB43_002980"
     CDS             5417..5899
                     /locus_tag="NOB43_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCI0983737.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="NOB43_002981"
     CDS             complement(6162..6629)
                     /locus_tag="NOB43_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCI0983738.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="NOB43_002982"
     CDS             6752..7603
                     /locus_tag="NOB43_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0983739.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /locus_tag="NOB43_002983"
     CDS             complement(7854..9812)
                     /locus_tag="NOB43_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0983740.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="NOB43_002984"
     CDS             complement(9809..10681)
                     /locus_tag="NOB43_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0983741.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="NOB43_002985"
     CDS             complement(11023..11895)
                     /locus_tag="NOB43_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0983742.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="NOB43_002986"
     CDS             12023..12592
                     /locus_tag="NOB43_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI0983743.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="NOB43_002987"
     CDS             12659..13396
                     /locus_tag="NOB43_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0983744.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="NOB43_002988"
     CDS             13627..14895
                     /locus_tag="NOB43_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0983745.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="NOB43_002989"
     CDS             15382..15846
                     /locus_tag="NOB43_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0983746.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="NOB43_002990"
     CDS             15830..16459
                     /locus_tag="NOB43_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0983747.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="NOB43_002991"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="NOB43_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI0983748.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="NOB43_002992"
     CDS             18338..18784
                     /locus_tag="NOB43_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI0983749.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="NOB43_002993"
     CDS             complement(18983..19498)
                     /locus_tag="NOB43_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0983750.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="NOB43_002994"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="NOB43_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6631 a         3703 c         4315 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctcagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DAIGTA010000241         8081 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.088, whole genome shotgun sequence.
ACCESSION   DAIGTA010000241 DAIGTA010000000
VERSION     DAIGTA010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.088"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            complement(134..577)
                     /locus_tag="NOB43_002995"
     CDS             complement(134..577)
                     /locus_tag="NOB43_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCI0983751.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="NOB43_002996"
     CDS             complement(795..2135)
                     /locus_tag="NOB43_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0983752.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="NOB43_002997"
     CDS             2404..3300
                     /locus_tag="NOB43_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI0983753.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="NOB43_002998"
     CDS             complement(3450..4391)
                     /locus_tag="NOB43_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI0983754.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="NOB43_002999"
     CDS             4517..5638
                     /locus_tag="NOB43_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0983755.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="NOB43_003000"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="NOB43_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI0983756.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="NOB43_003001"
     CDS             7426..7992
                     /locus_tag="NOB43_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0983757.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
BASE COUNT         2679 a         1508 c         1602 g         2292 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 ctggctcttt gtcaataagg actgatgagt tgtgcaaaat c
//
LOCUS       DAIGTA010000242         8072 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.089, whole genome shotgun sequence.
ACCESSION   DAIGTA010000242 DAIGTA010000000
VERSION     DAIGTA010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.089"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..251
                     /locus_tag="NOB43_003002"
     CDS             <1..251
                     /locus_tag="NOB43_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0983758.1"
                     /translation="LEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDN
                     LIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            486..722
                     /locus_tag="NOB43_003003"
     CDS             486..722
                     /locus_tag="NOB43_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0983759.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            729..2681
                     /locus_tag="NOB43_003004"
     CDS             729..2681
                     /locus_tag="NOB43_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI0983760.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2753..3250)
                     /gene="dfrG"
                     /locus_tag="NOB43_003005"
     CDS             complement(2753..3250)
                     /gene="dfrG"
                     /locus_tag="NOB43_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI0983761.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3612..4652
                     /locus_tag="NOB43_003006"
     CDS             3612..4652
                     /locus_tag="NOB43_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetM/TetW/TetO/TetS family tetracycline
                     resistance ribosomal protection protein"
                     /protein_id="HCI0983762.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQ
                     LKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSR
                     IDKVRYMFNKIT"
     gene            4762..4812
                     /locus_tag="NOB43_003007"
                     /pseudo
     CDS             4762..4812
                     /locus_tag="NOB43_003007"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            4846..6222
                     /gene="tet(L)"
                     /locus_tag="NOB43_003008"
     CDS             4846..6222
                     /gene="tet(L)"
                     /locus_tag="NOB43_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCI0983763.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            6817..7128
                     /locus_tag="NOB43_003009"
                     /pseudo
     CDS             6817..7128
                     /locus_tag="NOB43_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            7263..7910
                     /locus_tag="NOB43_003010"
     CDS             7263..7910
                     /locus_tag="NOB43_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HCI0983764.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT         2760 a         1194 c         1465 g         2653 t
ORIGIN      
        1 ttttagagaa atatatgtcc ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa
       61 gcataagatt tcagaattgt tctctgttcc ctctttatca tggaagtgca aaaagtaata
      121 tagggattga taaccttata gaagttatta ctaataaatt ttattcatca acacatcgag
      181 gtccgtctga actttgcgga aatgttttca aaattgaata tacaaaaaaa agacaacgtc
      241 ttgcatatta agtagttcag ttttggagta caaaaagtga aaatgtaaac ctaaatgagt
      301 atcaaattgc aactgaattt gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa
      361 tttacaccac aaaatgtaag ttaaaatgta tataaaaatg cgaacgtgaa ataattattg
      421 taggaatgca aattggtgtg ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt
      481 ttcctatgca atttcttgag ccaaaaaata agaacgctaa gtctgtggat tgggaaatat
      541 cagagcaagt aagggtgata gttaagcaat acgctgaata tgcagagcgt actgaaagcg
      601 aagcagtgga tgaattctta ttgaacattt tagacgataa gaagtttatt gaatggattg
      661 ccaacaagcg aagtaataag cggattgttg aaaaaatggg tatcaaagat agagtgggtt
      721 gatagacaat gaccaagctt aaaagattag ccacgaagga agatgaaatt gtagatgtta
      781 aaattccgat ttcaaacgaa gaattaaaag atagggctaa acaatatgat ttattaactc
      841 caaaacgatt tgcaacaagg tataacaaaa tgttgttctt gccaacgtct tttaaatgga
      901 acggttctga atatcccatt caatataatt actgcatcaa tccgttttgt tgtaattttg
      961 ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc aagtcgatat aaaatgactg
     1021 gtagttccaa agataaaggt cataaaggta tgtactgcaa tgacaatcct attggcagag
     1081 gtgtatcgca aaactgtaca gtaacccctt tatctaattg gtctgttgtt gaagaaatta
     1141 aacgccttat agaaatcaat agcatccaag atgttgagcc agattatcaa tttcataaag
     1201 aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg
     1261 ggaaaagtag gggcaaatct caacgctatc aatgtaaggc gtgtaagaag ttcactaatg
     1321 ttctaccaaa aagagaagaa accactactt atcaccaaca aaagaacacc attcttccaa
     1381 tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg tacttgtgat attttaggaa
     1441 ttggagttgg aacctactat cataagctgg agtggctgta taggcgttgt ttggagtttt
     1501 tagaacgata tgagacacaa ccccttcaaa caaagaaatt taacgagatg tggcttaata
     1561 cggacaagat gcactactac ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat
     1621 atacggggtt tgaagacctt aatatgcaaa cgtatatagt tgtatctgct gaggtcttat
     1681 caagatatgt gttccgttct gatgttgcct atgattggaa tatttcaatg gatgaattaa
     1741 atgaagatac aagaaaattc aaagaagacc atctcaatac ttttagtcgt aaaaatgata
     1801 ggttagattg gtcttattat ccacaagaac catccgctaa cgatagcgaa aataggaatg
     1861 cttatcttca cgaattaggg aaaattacta ataggagtag atttgtcgat ggtttaaatg
     1921 ttgatgctcc ttatactaca actgctcact attggttaat taaacaaatg gttaatgccg
     1981 acgaatggcg aatgattagt gatgatgact tctctattag aaacgccttt tatagagtat
     2041 tcacgaaaga attaaggttg agcgatgcac atcattttat ttgccaagtt aacaagacga
     2101 aaagcagaaa acaatgctta aaagaattcg gacaagcaaa agcagaactg ctcgattggg
     2161 gagatatcag aggattcaaa acaaagtttc tacggacttt ggcatctcat tatctaactg
     2221 aattactaac aagtcatcaa ttccacgaag aggctattag taaagatgga gaaagatatc
     2281 gcaaatatgc cgataaccct atcaaacatc cattagccac taaggataaa ggattttatt
     2341 cagttgattg tagaacggat ttatctgctc tggaaccaaa cgaaatcgca aagatgctat
     2401 taaatgttaa tgaccattcg accaatagct ttattcaaca gataagacgt tatatatcat
     2461 ctcttgaaag accattaaca acagctcgtg gtgataagaa gagctatatt tacgctaact
     2521 tcaatccgaa gtatgctcaa tttgcgatta caattctaag aacttactac aacttttgtc
     2581 gcccttttaa atcagcggat aaaaaggttt tgacacctgc tcaaagatta gggattacag
     2641 ataaacaatt tgattggaaa gatataattt atttcaaatg acaaaaagag cttggagtaa
     2701 tcccaagctc ttgtgcttta tctttactgt tcttcttcaa ttaacgcacc cgttaactca
     2761 ataagttttt tctttcatat acatgaaaat agtagttata cggattttta tcattcttta
     2821 tccctttttg ggcaaatacc tcattccatt cctcataatt cacttctgga aaaaaagtat
     2881 ctccttcgaa ttcatgatgt atttttgtga tgtacatttt ctcaacataa gggaaaaaca
     2941 aattataaat ctgttctcct ccgaaaataa aaatttcttc ttcgttttta cataactcaa
     3001 aaacatcttc tattgaatga acaatttcac aaccattaaa ggtaaacccc ttatctctcg
     3061 tcagaataat atttcttctg tcaggtaagg ctcttccgat tgattcaagg ttcttcctac
     3121 ctaatattat cggatgtccc tttgtagtat ttttaacata ttcccagtcc ttgggaatcc
     3181 tccaaggaat gtcattctct ttgccaatca ctctattctt atccatcgca gcaatcaaag
     3241 aaactttcat ttataacaca gcctttttaa ctaatttacc atctaatttc ttatttctat
     3301 caaaaaacct tttctcatta tcctgcccgt tagttgaata agcaattttt tctataagtt
     3361 atattatcat aataccacaa aatcacaaat tttcattcaa ttatcatttt caattgcatt
     3421 ttataaatca ttttgtatgt aatttggtat gtaagttaaa atgaaaaaag tagtccattt
     3481 tgaagtacat tttgtcattt tgtactccaa aactgaacta cttacttgca tatatacgcc
     3541 tttatagtgg agtactacat ttacgagatt cggttagagt atcagaaaaa gaaaaaataa
     3601 aagttacaga aatgtatact tcaataaatg gtgaattatg taagattgat agagcttatt
     3661 ctggagaaat tgttattttg caaaatgagt ttttgaagtt aaatagtgtt cttggagata
     3721 caaaactatt gccacagaga aaaaagattg aaaatccgca ccctctacta caaacaactg
     3781 ttgaaccgag taaacctgaa cagagagaaa tgttgcttga tgcccttttg gaaatctcag
     3841 atagtgatcc gcttctacga tattacgtgg attctacgac acatgaaatt atactttctt
     3901 tcttagggaa agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg
     3961 agatagaact aaaagagcct acagtcattt atatggagag accgttaaaa aatgcagaat
     4021 ataccattca catcgaagtg ccgccaaatc ctttctgggc ttccattggt ttatctgtat
     4081 caccgcttcc gttgggaagt ggaatgcagt atgagagctc ggtttctctt ggatacttaa
     4141 atcaatcatt tcaaaatgca gttatggaag ggatacgcta tggttgcgaa caaggattat
     4201 atggttggaa tgtgacggat tgtaaaatct gttttaagta tggcttatac tatagccctg
     4261 ttagtacccc agcagatttt cggatgcttg ctcctattgt attggaacaa gtcttaaaaa
     4321 aagctggaac agaattgtta gagccatatc ttagttttaa aatttatgcg ccacaggaat
     4381 atctttcacg agcatacaac gatgctccta aatattgtgc gaacatcgta gacactcaat
     4441 tgaaaaataa tgaggtcatt cttagtggag aaatccctgc tcggtgtatt caagaatatc
     4501 gtagtgattt aactttcttt acaaatggac gtagtgtttg tttaacagag ttaaaagggt
     4561 accatgttac taccggtgaa cctgtttgcc agccccgtcg tccaaatagt cggatagata
     4621 aagtacgata tatgttcaat aaaataactt agtgtatttt atgttgttat ataaatatgg
     4681 tttcttgtta aataagatga aatatttttt aataaagatt tgaattaaag tgtaaaggag
     4741 gaattaatta tgaagtgaaa tgaatgtaac agggttcaat taaaagaggg aagcgtatca
     4801 ttaaccctat aaactacgtc tgccctcatt attggagggt gaaatgtgaa tacatcctat
     4861 tcacaatcga atttacgaca caaccaaatt ttaatttggc tttgcatttt atcttttttt
     4921 agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa tgattttaat
     4981 aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt ttccattgga
     5041 acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact cctatttgga
     5101 attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt cttttcctta
     5161 cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc actcgtaatg
     5221 gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg tcttattgga
     5281 tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat agcccattat
     5341 attcattggt cctatcttct actcattcct atgataacaa ttatcactgt tccgtttctt
     5401 atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa aggaattata
     5461 ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag catttctttt
     5521 cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa agtaacagat
     5581 ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt tctttgtggg
     5641 ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat gatgaaagat
     5701 gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg aacaatgagt
     5761 gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc tttatacgtg
     5821 ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt tcttttagaa
     5881 acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct ttcgttcacc
     5941 aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc tggtgctgga
     6001 atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc aattgtaggt
     6061 ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt tgatcagtca
     6121 acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat tagttggctg
     6181 gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa gggatcaact
     6241 ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc tttttgttcc
     6301 attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat cttttttatt
     6361 ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt tattcttgct
     6421 gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca agggtttaaa
     6481 ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc tgatttttaa
     6541 acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt tttttgtttc
     6601 ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc ggcactgccg
     6661 acagcctcgc agagcccacc tttacgaagt aaagtatagt gtgttatact ttacatggaa
     6721 gttgtaccga aatattgtgt tgtgaagtct atataatttt aaaattatga agtctatata
     6781 cgtgcgtaaa gatatttaaa gagattaaaa ataataaaaa taaaaattga attaaaaaga
     6841 gatatggttg attattggaa cgattgtttt aatgatttac atatattaca accagattgg
     6901 aaaactatcg aacgtacttc tgatagagca atggttttta tgttgttgaa tgatgaagaa
     6961 gaatggggaa aattagaaag acgtactaag aataaatata aaaaattaat taaagaaata
     7021 tctctaattg atttaactga tttaatgaaa tcgactttaa aagcgaacga aaaacaattg
     7081 caaaagcaga ttgatttttg gcaacgtgaa tttagatttt ggaagtaaag taactttgtt
     7141 ttatacaaaa tgttacttta gtataattaa cgtttaagag gtgacacaat atatgaaaaa
     7201 atcagaggat tattcctcct aaatacaaag agataagatg aaatttagga ggaaaattat
     7261 atatgacttt taatattatt aatttggaaa cttgggatag aaaagaatat tttaatcatt
     7321 atttcaatca acaaacaact tacagtgtta ctaaagaatt tgatatcact ttacttaaaa
     7381 gtatgataaa aaataaagga tatgaactgt atcctgcttt gatttataca attgtaaata
     7441 ttataaatca aaataaagta tttagaacag gaattaatag tgagggaaat ttgggttatt
     7501 gggaaaaatt aaacccttta tatacagtct ttaataaaga aactgaaaaa ttttctaaca
     7561 tttggacaga atcaaatgtt agttttaatt ctttttataa tagttataag agtgacttac
     7621 ttgaatataa agataaaaat gaaatgtttc ctaaaaaacc aatacctgaa aacacagttc
     7681 ctatttcgat gattccttgg attgatttta gttcatttaa tttaaatatt ggtaataata
     7741 gtagattcct attgccaatt attacaatag gtaaatttta tagtaagaat aataagatct
     7801 atttaccagt ctcattgcaa gttcatcatg cggtatgtga tggttaccat gtttcattat
     7861 ttatgagtga atttcaaaat atagttgata gtgtaaatga atggatttaa atctaaaata
     7921 actttcataa acttaagtaa ttatgatatt tataagttta tagcaactac catttttggt
     7981 tgctggtgtt ttgattttga atttggtttt gaacttatgg actgatttat tcaggctctt
     8041 tgtcaaatga tgttggtaaa gagaaatctt ag
//
LOCUS       DAIGTA010000243         7780 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.091, whole genome shotgun sequence.
ACCESSION   DAIGTA010000243 DAIGTA010000000
VERSION     DAIGTA010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.091"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            245..1213
                     /locus_tag="NOB43_003011"
     CDS             245..1213
                     /locus_tag="NOB43_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI0983765.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1206..2237
                     /gene="vanA"
                     /locus_tag="NOB43_003012"
     CDS             1206..2237
                     /gene="vanA"
                     /locus_tag="NOB43_003012"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI0983766.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2243..2851
                     /locus_tag="NOB43_003013"
     CDS             2243..2851
                     /locus_tag="NOB43_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI0983767.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3279..4190
                     /gene="vanY"
                     /locus_tag="NOB43_003014"
     CDS             3279..4190
                     /gene="vanY"
                     /locus_tag="NOB43_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HCI0983768.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4343..4828
                     /gene="vanZ"
                     /locus_tag="NOB43_003015"
     CDS             4343..4828
                     /gene="vanZ"
                     /locus_tag="NOB43_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCI0983769.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5115..5444)
                     /locus_tag="NOB43_003016"
     CDS             complement(5115..5444)
                     /locus_tag="NOB43_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0983770.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5749..6078
                     /locus_tag="NOB43_003017"
     CDS             5749..6078
                     /locus_tag="NOB43_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0983771.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6068..6355
                     /locus_tag="NOB43_003018"
     CDS             6068..6355
                     /locus_tag="NOB43_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0983772.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6634..7197)
                     /locus_tag="NOB43_003019"
     CDS             complement(6634..7197)
                     /locus_tag="NOB43_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0983773.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2566 a         1297 c         1546 g         2371 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
      121 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
      181 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
      241 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
      301 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
      361 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
      421 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
      481 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
      541 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
      601 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
      661 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
      721 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
      781 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
      841 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
      901 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
      961 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
     1021 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
     1081 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
     1141 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
     1201 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
     1261 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
     1321 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
     1381 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
     1441 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
     1501 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
     1561 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
     1621 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
     1681 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
     1741 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
     1801 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
     1861 tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga ccaaatcagg ctgcagtacg
     1921 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
     1981 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
     2041 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
     2101 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
     2161 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
     2221 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     2281 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     2341 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     2401 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     2461 tcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     2521 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     2581 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     2641 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     2701 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     2761 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     2821 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     2881 taagctaact ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat
     2941 atagtagata gtattgaaga tgtaaggcag agcgatattg cggtcattat ctgcgtgcgc
     3001 tgcggcaaga tagcctgata ataagactga tcgcatagag gggtggtatt tcacaccgcc
     3061 cattgtcaac aggcagttca gcctcgttaa attcagcatg ggtatcactt atgaaaattc
     3121 atctacattg gtgataatag taaatccagt agggcgaaat aattgactgt aatttacggg
     3181 gcaaaacggc acaatctcaa acgagattgt gccgtttaag gggaagattc tagaaatatt
     3241 tcatacttcc aactatatag ttaaggagga gactgaaaat gaagaagttg ttttttttat
     3301 tgttattgtt attcttaata tacttaggtt atgactacgt taatgaagca ctgttttctc
     3361 aggaaaaagt cgaatttcaa aattatgatc aaaatcccaa agaacattta gaaaatagtg
     3421 ggacttctga aaatacccaa gagaaaacaa ttacagaaga acaggtttat caaggaaatc
     3481 tgctattaat caatagtaaa tatcctgttc gccaagaaag tgtgaagtca gatatcgtga
     3541 atttatctaa acatgacgaa ttaataaatg gatacgggtt gcttgatagt aatatttata
     3601 tgtcaaaaga aatagcacaa aaattttcag agatggtcaa tgatgctgta aagggtggcg
     3661 ttagtcattt tattattaat agtggctatc gagactttga tgagcaaagt gtgctttacc
     3721 aagaaatggg ggctgagtat gccttaccag caggttatag tgagcataat tcaggtttat
     3781 cactagatgt aggatcaagc ttgacgaaaa tggaacgagc ccctgaagga aagtggatag
     3841 aagaaaatgc ttggaaatac gggttcattt tacgttatcc agaggacaaa acagagttaa
     3901 caggaattca atatgaacta tggcatattc gctatgttgg tttaccacat agtgcgatta
     3961 tgaaagaaaa gaatttcgtt ctcgaggaat atatggatta cctaaaagaa gaaaaaacca
     4021 tttctgttag tgtaaatggg gaaaaatatg agatctttta ttatcctgtt actaaaaata
     4081 ccaccattca tgtgccgact aatcttcgtt atgagatatc aggaaacaat atagacggtg
     4141 taattgtgac agtgtttccc ggatcaacac atactaattc aaggaggtaa ggatggcgga
     4201 atgaaaccaa cgaaattaat gaacagcatt attgtactag cacttttggg gtaacgttag
     4261 ctttttaatt taaaacccac gttaactagg acattgctat actaatgata caacttaaac
     4321 aaaagaatta gaggaaatta tattgggaaa aatattatct agaggattgc tagctttata
     4381 tttagtgaca ctaatctggt tagtgttatt caaattacaa tacaatattt tatcagtatt
     4441 taattatcat caaagaagtc ttaacttgac tccatttact gctactggga atttcagaga
     4501 gatgatagat aatgttataa tctttattcc atttggcttg cttttgaatg tcaattttaa
     4561 agaaatcgga tttttaccta agtttgcttt tgtactggtt ttaagtctta cttttgaaat
     4621 aattcaattt atcttcgcta ttggagcgac agacataaca gatgtaatta caaatactgt
     4681 tggaggcttt cttggactga aattatatgg tttaagcaat aagcatatga atcaaaaaaa
     4741 attagacaga gttattattt ttgtaggtat acttttgctc gtattattgc tcgtttaccg
     4801 tacccattta agaataaatt acgtgtaaga tgtctaaatc aagcaatctg atctttcata
     4861 cacataaaga tattgaatga attggattag atggaaaacg ggatgtgggg aaactcgccc
     4921 gtaggtgtga agtgagggga aaaccggtga taaagtaaaa agcttaccta acactatagt
     4981 aacaaagaaa gcccaattat caattttagt gctgaggaat tggtctcttt aataaatttc
     5041 cttaacgttg taaatccgca ttttcctgac ggtaccccca aactaagatt tcatagatag
     5101 attttctgat aactttaaaa aacacgaata gcggaaagga tgtcttcatt cgctaaagag
     5161 taataaacta cttttccatc ttgacgtgat tttgccattc catgtttttt taaaaaacgt
     5221 aaatggtgtg acgttgtagc gacactagca gtaagtattt ctgctaaatc acagacgcac
     5281 atttccttat aggtttctaa agcatagaaa attttaattc tagaaaaatc gctgaaacat
     5341 ttccctaaca caagtaagtt tgaaaaatct ttttgatcca atttattttt tattccattt
     5401 actttttctt tatgtacgac agtcacttgg caaacttttt tcattcatct cacctcacat
     5461 tcaaacgatt atttgaatga agtataccta tttgatcact cttttgtcaa tctaccttaa
     5521 ttccaataca ctattataag caatttcatg tattgaagta aacttacttg caagtgcgtt
     5581 tttgattcca agttaaaaac atattattat tctacataat ttcctaatca aataaaactc
     5641 ctttgaaaat tgttctaaag gagttttatt attttgtatt tctactaaaa atagcgtaca
     5701 atgtaattac taagtaatta cgaaatgtaa aataatggag gaaataatat gattacaaaa
     5761 acaagaaaac aaggaaattc tattatgtta acggtcccta aagaattcga tgtgcccaat
     5821 ggtgttgaag tagaagctaa gcttgtagag aatggtatcc tttatgagtt tgtagagcct
     5881 aaaaaagaat tttttgattt tagtgaagat attttggctg atattctttc agaaggttat
     5941 agcaaacaag agatcttaaa agaatttaga aatagaaaaa atgcgttaac ttctgcattt
     6001 aaatctattg ctgaagatac tgttgcaaat tctaaaccga tgacaaaaga ggagttggca
     6061 gcagaaattg gcttatgaga ttctaccttc taaacacgta ataaagtatc taaaaaaatt
     6121 aaaagagaaa acattaaaag aacaattttt aacgataatt tatgatgaga tagcagttcg
     6181 tcctcattcg ggagaacaaa aaacgggtga tttatcagga atttgggcta ttggattcaa
     6241 gtatgcaggt acgacatatc gcgttgcata tgaaattaaa gataatgcag tgatacctat
     6301 cttactatgt ggaacgcatg aaaattttta tgaacaatta aaaaagatta ggtaagaacc
     6361 caatgtttca acttgagagg atagacgaca ctttaaaaga taatttttaa cagctgagag
     6421 ttgtaatacc ctataatttt aaaccactaa cctatatatt tatgaaaaat agaaaaaatt
     6481 aaaacgcatt ttaagcctct ttcaaattaa aagcttcatc cttatgcaca aagagggctt
     6541 aaaatgcgtt attttatatt gttttttagt aataataaaa aaatcactct aattctccca
     6601 taaatattat agattcctaa agattaaaat agattattcc ctattgtctt ttaagtagcg
     6661 gtagagtgtt gccttgctaa taccagtcat ttccgtaatt tcttttacgc tataaacctg
     6721 acttttatac aattttactg ctcgatcaac atctttctgg ttcactcgtg gacggccacc
     6781 tttacgacct ctcgcacgtg cacttttcaa accttctttg gtacgttcaa caattaaatc
     6841 acgttcgaac tgactaaatg cttggaagac agtcatcatt aagcgtccgt gaggcgtgct
     6901 ggtatcgaag ttttctttca agctcaccag cttaacatgg tgttcttcaa aataggtaac
     6961 aaggtcaatc aaatcctttg tactacgacc caatcgagaa aaactttcta caattaccgt
     7021 atctcccgga cgaattttat cttttaaacg atttagttgg ggacgaaccg ctttggttcc
     7081 cgtcattttc tcagttagga tttcattaca attttgttca ttgagtaagt ctaattgacg
     7141 atttagttct tgtgaacgtg tactcactcg ggcataacca taaatgtatc cactcatgct
     7201 tttcttcctt tcgtacttta attctggctt gattgtatca taaaagggag ttatagatac
     7261 atagttaatg caacaagtta tgatacaaaa tatgacctct tttatttaat aaaagaggtc
     7321 atttcatttt gtctcataat cgattgtttt tgatacgagt gtgtatacga aataaacaaa
     7381 aaaatcttaa gtaaatttct agatacctaa tttaatccta actagtgtat cctaaagtta
     7441 ataacgagtt tatcacaatg aaaattataa aatgctccca tattagatat aacatgcaat
     7501 atttgaatta gaactacaaa atttattcgt tttataaagt aaataatgtt gagatactaa
     7561 ggaatagaat attataagga attgagctga atgtattgga taaaaaaaga ataactttat
     7621 tagagatgga ctataaaaat gctcgtaatt ttcttctgaa gtctgaaagc tatttgaatg
     7681 ctcagctacc agaatatatt agttttgacg aaactttaaa atctgctaaa aaagttttaa
     7741 cttcgccgtt tgtataatta agcgagacaa ataaaaaagc
//
LOCUS       DAIGTA010000244         5401 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.108, whole genome shotgun sequence.
ACCESSION   DAIGTA010000244 DAIGTA010000000
VERSION     DAIGTA010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.108"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            62..1981
                     /gene="tet(M)"
                     /locus_tag="NOB43_003020"
     CDS             62..1981
                     /gene="tet(M)"
                     /locus_tag="NOB43_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCI0983774.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSMEIIIKQKVEL
                     HPNMCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2091..2141
                     /locus_tag="NOB43_003021"
                     /pseudo
     CDS             2091..2141
                     /locus_tag="NOB43_003021"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            2175..3551
                     /gene="tet(L)"
                     /locus_tag="NOB43_003022"
     CDS             2175..3551
                     /gene="tet(L)"
                     /locus_tag="NOB43_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCI0983775.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            4146..4457
                     /locus_tag="NOB43_003023"
                     /pseudo
     CDS             4146..4457
                     /locus_tag="NOB43_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            4592..5239
                     /locus_tag="NOB43_003024"
     CDS             4592..5239
                     /locus_tag="NOB43_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HCI0983776.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT         1813 a          750 c         1042 g         1796 t
ORIGIN      
        1 taaaagtatt tatcactggg atttttatgc ccttttgggt ttttgaatgg aggaaaatca
       61 catgaaaatt attaatattg gagttttagc tcatgttgat gcaggaaaaa ctaccttaac
      121 agaaagctta ttatataaca gtggagcgat tacagaatta ggaagcgtgg acaaaggtac
      181 aacgaggacg gataatacgc ttttagaacg tcagagagga attacaattc agacaggaat
      241 aacctctttt cagtgggaaa atacgaaggt gaacatcata gacacgccag gacatatgga
      301 tttcttagca gaagtatatc gttcattatc agttttagat ggggcaattc tactgatttc
      361 tgcaaaagat ggcgtacaag cacaaactcg tatattattt catgcactta ggaaaatggg
      421 gattcccaca atctttttta tcaataagat tgaccaaaat ggaattgatt tatcaacggt
      481 ttatcaggat attaaagaga aactttctat ggaaattata atcaaacaga aagtagagct
      541 gcaccctaat atgtgtgtga tgagctgtac ggaacctgag caatgggatg tggtaataga
      601 aggaaatgat gaccttttag agaaatatat gtccggtaaa tcattagaag cattagaact
      661 cgaacaagag gaaatcagaa gatttcagaa ttgctccttg taccctgttt atcatggaag
      721 cgcaaaaagc aacataggga ttgagcagct tatagaagtg ataacgaata aattttattc
      781 atcaacatac agaaagaagt ctgaactttg cggaaatgtc ttcaaaattg aatattcgga
      841 agaaagacaa cgtcttgcat atgtacgcct ttatggcgga atcctgcatt tgcgggattc
      901 ggttagaata tcggaaaagg aaaaaataaa aattacagaa atgtatactt caataaatgg
      961 tgaattatgt aaaattgata aggcttattc cggggaaatt gttattttgc aaaatgagtt
     1021 tttgaagcta aatagtgttc ttggagatac aaagctattg ccacagagag agagaattga
     1081 aaatccgctc cctctgctgc aaacaactgt tgaaccgagc aaacctcaac aaagggaaat
     1141 gttacttgat gcacttttag aaatctccga cagtgacccg cttctacaat attatgtgga
     1201 ttctacgaca catgaaatta tactttcttt cttagggaaa gtacaaatgg aagtgattag
     1261 tgcactgttg caagaaaagt atcatgtgga gatagaacta aaagagccta cagtcattta
     1321 tatggagaga ccgttaaaaa atgcagaata taccattcac atcgaagtgc cgccaaatcc
     1381 tttctgggct tccattggtt tatctgtatc accgcttccg ttgggaagtg gaatgcagta
     1441 tgagagctcg gtttctcttg gatacttaaa tcaatcattt caaaatgcag ttatggaagg
     1501 gatacgctat ggttgcgaac aaggattata tggttggaat gtgacggatt gtaaaatctg
     1561 ttttaagtat ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc
     1621 tcctattgta ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct
     1681 tagttttaaa atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa
     1741 atattgtgcg aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga
     1801 aatccctgct cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg
     1861 tagtgtttgt ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca
     1921 gccccgtcgt ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta
     1981 gtgtatttta tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta
     2041 ataaagattt gaattaaagt gtaaaggagg aattaattat gaagtgaaat gaatgtaaca
     2101 gggttcaatt aaaagaggga agcgtatcat taaccctata aactacgtct gccctcatta
     2161 ttggagggtg aaatgtgaat acatcctatt cacaatcgaa tttacgacac aaccaaattt
     2221 taatttggct ttgcatttta tcttttttta gcgtattaaa tgaaatggtt ttgaacgtct
     2281 cattacctga tattgcaaat gattttaata aaccacctgc gagtacaaac tgggtgaaca
     2341 cagcctttat gttaaccttt tccattggaa cagctgtata tggaaagcta tctgatcaat
     2401 taggcatcaa aaggttactc ctatttggaa ttataataaa ttgtttcggg tcggtaattg
     2461 ggtttgttgg ccattctttc ttttccttac ttattatggc tcgttttatt caaggggctg
     2521 gtgcagctgc atttccagca ctcgtaatgg ttgtagttgc gcgctatatt ccaaaggaaa
     2581 ataggggtaa agcatttggt cttattggat cgatagtagc catgggagaa ggagtcggtc
     2641 cagcgattgg tggaatgata gcccattata ttcattggtc ctatcttcta ctcattccta
     2701 tgataacaat tatcactgtt ccgtttctta tgaaattatt aaagaaagaa gtaaggataa
     2761 aaggtcattt tgatatcaaa ggaattatac taatgtctgt aggcattgta ttttttatgt
     2821 tgtttacaac atcatatagc atttcttttc ttatcgttag cgtgctgtca ttcctgatat
     2881 ttgtaaaaca tatcaggaaa gtaacagatc cttttgttga tcccggatta gggaaaaata
     2941 taccttttat gattggagtt ctttgtgggg gaattatatt tggaacagta gcagggtttg
     3001 tctctatggt tccttatatg atgaaagatg ttcaccagct aagtactgcc gaaatcggaa
     3061 gtgtaattat tttccctgga acaatgagtg tcattatttt cggctacatt ggtgggatac
     3121 ttgttgatag aagaggtcct ttatacgtgt taaacatcgg agttacattt ctttctgtta
     3181 gctttttaac tgcttccttt cttttagaaa caacatcatg gttcatgaca attataatcg
     3241 tatttgtttt aggtgggctt tcgttcacca aaacagttat atcaacaatt gtttcaagta
     3301 gcttgaaaca gcaggaagct ggtgctggaa tgagtttgct taactttacc agctttttat
     3361 cagagggaac aggtattgca attgtaggtg gtttattatc cataccctta cttgatcaaa
     3421 ggttgttacc tatggaagtt gatcagtcaa cttatctgta tagtaatttg ttattacttt
     3481 tttcaggaat cattgtcatt agttggctgg ttaccttgaa tgtatataaa cattctcaaa
     3541 gggatttcta aatcgttaag ggatcaactt tgggagagag ttcaaaattg atcctttttt
     3601 tataacagga attcaaatct ttttgttcca ttaaagggcg cgattgctga ataaaagata
     3661 cgagagacct ctcttgtatc ttttttattt tgagtggttt tgtccgttac actagaaaac
     3721 cgaaagacaa taaaaatttt attcttgctg agtctggctt tcggtaagct agacaaaacg
     3781 gacaaaataa aaattggcaa gggtttaaag gtggagattt tttgagtgat cttctcaaaa
     3841 aatactacct gtcccttgct gatttttaaa cgagcacgag agcaaaaccc ccctttgctg
     3901 aggtggcaga gggcaggttt ttttgtttct tttttctcgt aaaaaaaaga aaggtcttaa
     3961 aggttttatg gttttggtcg gcactgccga cagcctcgca gagcccacct ttacgaagta
     4021 aagtatagtg tgttatactt tacatggaag ttgtaccgaa atattgtgtt gtgaagtcta
     4081 tataatttta aaattatgaa gtctatatac gtgcgtaaag atatttaaag agattaaaaa
     4141 taataaaaat aaaaattgaa ttaaaaagag atatggttga ttattggaac gattgtttta
     4201 atgatttaca tatattacaa ccagattgga aaactatcga acgtacttct gatagagcaa
     4261 tggtttttat gttgttgaat gatgaagaag aatggggaaa attagaaaga cgtactaaga
     4321 ataaatataa aaaattaatt aaagaaatat ctctaattga tttaactgat ttaatgaaat
     4381 cgactttaaa agcgaacgaa aaacaattgc aaaagcagat tgatttttgg caacgtgaat
     4441 ttagattttg gaagtaaagt aactttgttt tatacaaaat gttactttag tataattaac
     4501 gtttaagagg tgacacaata tatgaaaaaa tcagaggatt attcctccta aatacaaaga
     4561 gataagatga aatttaggag gaaaattata tatgactttt aatattatta atttggaaac
     4621 ttgggataga aaagaatatt ttaatcatta tttcaatcaa caaacaactt acagtgttac
     4681 taaagaattt gatatcactt tacttaaaag tatgataaaa aataaaggat atgaactgta
     4741 tcctgctttg atttatacaa ttgtaaatat tataaatcaa aataaagtat ttagaacagg
     4801 aattaatagt gagggaaatt tgggttattg ggaaaaatta aaccctttat atacagtctt
     4861 taataaagaa actgaaaaat tttctaacat ttggacagaa tcaaatgtta gttttaattc
     4921 tttttataat agttataaga gtgacttact tgaatataaa gataaaaatg aaatgtttcc
     4981 taaaaaacca atacctgaaa acacagttcc tatttcgatg attccttgga ttgattttag
     5041 ttcatttaat ttaaatattg gtaataatag tagattccta ttgccaatta ttacaatagg
     5101 taaattttat agtaagaata ataagatcta tttaccagtc tcattgcaag ttcatcatgc
     5161 ggtatgtgat ggttaccatg tttcattatt tatgagtgaa tttcaaaata tagttgatag
     5221 tgtaaatgaa tggatttaaa tctaaaataa ctttcataaa cttaagtaat tatgatattt
     5281 ataagtttat agcaactacc atttttggtt gctggtgttt tgattttgaa tttggttttg
     5341 aacttatgga ctgatttatt caggctcttt gtcaaatgat gttggtaaag agaaatctta
     5401 g
//
LOCUS       DAIGTA010000245         5099 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.110, whole genome shotgun sequence.
ACCESSION   DAIGTA010000245 DAIGTA010000000
VERSION     DAIGTA010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.110"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            388..471
                     /locus_tag="NOB43_003025"
     CDS             388..471
                     /locus_tag="NOB43_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HCI0983777.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            596..1333
                     /gene="erm(B)"
                     /locus_tag="NOB43_003026"
     CDS             596..1333
                     /gene="erm(B)"
                     /locus_tag="NOB43_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI0983778.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1596..1712)
                     /locus_tag="NOB43_003027"
     CDS             complement(1596..1712)
                     /locus_tag="NOB43_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta-toxin"
                     /protein_id="HCI0983779.1"
                     /translation="MVQNQHQETPEFKAIQQKLESLQPPTPPIPKTPKLPGI"
     gene            1975..2487
                     /locus_tag="NOB43_003028"
                     /pseudo
     CDS             1975..2487
                     /locus_tag="NOB43_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337518.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2559..4172)
                     /locus_tag="NOB43_003029"
     CDS             complement(2559..4172)
                     /locus_tag="NOB43_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI0983780.1"
                     /translation="MNEKFARWNVLFIQYVKRDWKKIIVWVLGLGLFSGAFVPAFEEI
                     AKGQGLLGMFETMQNPAMISMVGPTPIKIGTDYTLGAMYAQEMLLFCGLFAMIISALH
                     VVSHTRKEEELGLTELVRSFRVGRQANSLAVISEMLLINLLLGLLIGGLMMSFGVKTI
                     DAEGAFLFGGSIALAGIIGGVLALVMSQIMATSTGATGSTLSLIGLLYIVRAGTDVSN
                     LDLSMFNPMGWIYLTYPFTENNWLPLLFALIFSLVFTVLAFVLEEHRDMGAGYLPERE
                     GRATAKKSLLSVPGLFFKINKGVMIGWLIAFVVMGAAYGSIYGDMQVFLGGNELMKQM
                     FTQSGVSIEESFTATIMMVMIGLVTILPIAVVNKLFAEETRLHLSQLYVTKITRGQLY
                     WTTIFLAIFAGVVGIGLASAGLGGTAISAMKNESTMDLTDFLAAGYNFLPSILFYIGL
                     AALALGWLPKFGKVIYAYLGYSFALNYFGGILDLPDWFSKTAIQSWIPRLPMEKFDGT
                     IFAVITVISIVFLFVGYLGYKRRDMVEGA"
     gene            complement(4196..5050)
                     /locus_tag="NOB43_003030"
     CDS             complement(4196..5050)
                     /locus_tag="NOB43_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0983781.1"
                     /translation="MQKKFGKFQALKDVSFTVNAGEVVGFIGPNGAGKSTTIRTLLGI
                     INRDEGDVQIFGKDVWKDSLEIHKRISYVPGDVALWGSLTGGEIIDLFIKLHGGGSKA
                     KRDYLIKRFELDPKKKAKGYSKGNRQKVGLIAALSVESDLYILDEPTSGLDPLMEAVF
                     QEEVEKIKNDGKAILLSSHILSEVERLADKVAIIRRGEVVETGTLDELRHLTRSTVTL
                     VTEGDIEKLATLSGVHDFVQKDGKATFSADNEAMNTILTEATKLGVTKIESVPPTLED
                     LFMRHYEG"
BASE COUNT         1639 a         1005 c          880 g         1575 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacct tttgtacatt taacttgacg
       61 gtgacatctc tctattgtga gttattagtg gtacagtttt caaccgtttt aattataaaa
      121 aagtggtgca tttttaaatt ggcacaaaca ggtaacggtt attgcaggtg tatttcttat
      181 ctatgggttt aacatggatt ttatcattaa aatcatgagt attgtccgag agtgattggt
      241 cttgcgtatg gttaacccta aagttatgga aataagactt agaagcaaac ttaagagtgt
      301 gttgatagtg cattaaaaat tttgtataat aggaattgaa gttaaattag atgctaaaaa
      361 tttgtaatta agaaggaggg attcgtcatg ttggtattcc aaatgcgtta tgtagataaa
      421 acatctactg ttttgaaaca gactaaaaac agtgattacg cagataaata aatacgttag
      481 attaattcct accagtgact aatcttatga ctttttaaac agataactaa aattacaaac
      541 aaatcgttta acttctgtat ttgtttatag atgtaatcac ttcaggagtg attacatgaa
      601 caaaaatata aaatattctc aaaacttttt aacgagtgaa aaagtactca accaaataat
      661 aaaacaattg aatttaaaag aaaccgatac cgtttacgaa attggaacag gtaaagggca
      721 tttaacgacg aaactggcta aaataagtaa acaggtaacg tctattgaat tagacagtca
      781 tctattcaac ttatcgtcag aaaaattaaa actgaatact cgtgtcactt taattcacca
      841 agatattcta cagtttcaat tccctaacaa acagaggtat aaaattgttg ggagtattcc
      901 ttaccattta agcacacaaa ttattaaaaa agtggttttt gaaagccatg cgtctgacat
      961 ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc gaacactagg
     1021 gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag cggaatgctt
     1081 tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata ccacagatgt
     1141 tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca atcgagaata
     1201 tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca aagtaaacaa
     1261 tttaagtacc gttacttatg agcaagtatt gtctattttt aatagttatc tattatttaa
     1321 cgggaggaaa taattctatg agtcgctttt gtaaatttgg aaagttacac gttactaaag
     1381 ggaatgtaga taaattatta ggtatagggc acctctaata actaccaatt aattcacctc
     1441 aaaatgaaat tagaaaaaaa cagcgaaatt tttaaatcta tttcttatcg atacaaattc
     1501 ctcgtaggcg ctcgggaccc caacatgagg aaatgttttt ataaaaaaag agtagttacc
     1561 gttttttggt aactactctt ttcctttttt aaggtttaaa tacctggaag tttaggtgtt
     1621 ttgggtattg gtggtgtagg tggctgcaag ctttccaatt tttgttgaat tgctttaaat
     1681 tcaggggttt cttggtgttg attttgaacc attttttgct ctattctctc caaagtcggt
     1741 tgaatttctt tccctgatac tttacgattt aattctcttt ctaaggtctc tttcggacta
     1801 atggaaggcg tttctaagct tgaatagagt ttcactcctt ctctattgta aagccttata
     1861 tcgctaaata agcccgtttt atgaagggtt tctaaattgg tcggtaagtt tttgacaaca
     1921 atatcatgcg cttgttttgg tggtgcccta gctgtcattg gatcatctgc atacaataag
     1981 atccatgaaa ggccatctgc tgccaatgag cgccttgaga ttggtaattg ggaagctgat
     2041 actgtagccg gtaaaacagg tagggctcgt attgtaactc tagtcgatcg tagatctcgt
     2101 ttctccctac ttggtaaggt tgaaaagaaa atctctaaaa atgtggttga ttgtatgatc
     2161 aatctactaa gaaatgtagg agaagataaa tgtaaaaccg ttacacccga tagaggaaaa
     2221 gaattctccc aacatagtcg aataacgcta gaattaaatg gcactaaagt gtattttcca
     2281 gatccacatg ctccatggca acgtggtaca aacgaaaata ctaatggttt attacgagaa
     2341 tattcaccca aaggtgaaga tatttcaggt attttcgata gtcaaattca agaatgggcg
     2401 aataaattaa acacgcgacc acggaaatgt ctaaattgga aaacccctta tgaagtattt
     2461 tttaatgaat cgttgcactt aatttgacaa ttgaagccat aaaaaaaccg ctcaaatcga
     2521 ctttcgtaaa tatgaacggt tttttagaaa ttcaattttt aagcgccttc taccatatca
     2581 cggcgtttgt atcctaaata gccgacaaat aagaagacga tactgataac agtaattact
     2641 gcaaaaatcg ttccatcaaa tttttccatc ggtaagcgtg gaatccaact ttgaattgca
     2701 gtttttgaga accaatccgg caaatctaag attccgccga aataattcaa agcaaaggaa
     2761 tagcctagat aagcatagat tacttttcca aattttggca accagcctaa cgctaaagca
     2821 gccaaaccaa tataaaataa gatggaaggg agaaaattgt atccagcagc taagaaatcg
     2881 gtcagatcca tagtcgattc atttttcatc gcagaaatcg ccgttccacc taatcccgct
     2941 gatgctaagc caatacctac gactccagca aaaatagcta aaaatatcgt tgtccaatat
     3001 aattggcctc gcgtaatctt cgttacatac agttgactca gatgcagtct tgtttcttct
     3061 gcaaataatt tattgaccac cgcgattggc aagattgtga ctaatccaat cattaccatc
     3121 atgatcgttg ccgtaaagga ttcttcaatg gaaacgccag attgagtgaa catttgtttc
     3181 atcagttcat ttccgccaag aaagacttgc atgtctccat aaatggagcc atacgcagct
     3241 cccataacga caaatgcgat cagccaacca atcattactc ctttattaat cttgaaaaac
     3301 aaaccaggta cagaaagtag tgatttcttc gccgtcgcac gtccttctcg ttcaggaaga
     3361 taacctgcgc ccatgtcgcg atgttcttcc aacacaaacg caagtacggt aaaaacaaga
     3421 ctaaaaatca aagcaaataa taatggtagc cagttatttt ctgtgaaagg ataggtcaag
     3481 taaatccatc ccattggatt gaacattgat aaatcaagat tagacacatc tgttccagcg
     3541 cgcacgatat acaaaagtcc tataagactt aatgtcgagc cggttgctcc agtagaagtc
     3601 gccataatct gcgacatcac aagtgccaat acaccaccga taattcccgc caatgcaatt
     3661 gatcctccga acaagaaagc tccttcggca tcaatcgttt ttacaccaaa actcatcatg
     3721 agtccgccga ttaaaagacc taataaaaga ttgatcaaca gcatctcact gataacagct
     3781 aatgaattgg cttgtcgtcc tactcgaaat gagcgaacca attcagtcaa acctaattct
     3841 tcttcttttc gcgtgtggct caccacatga agtgctgaga taatcattgc gaacaatccg
     3901 caaaacagca acatctcttg agcatacatc gctcctaaag tataatccgt acctattttg
     3961 attggtgtag gtccaaccat cgagatcatc gctggatttt gcatcgtttc aaacatccct
     4021 aaaagacctt gtcctttagc aatctcttca aatgctggta caaatgctcc tgagaacaaa
     4081 cccaaaccta aaacccaaac aattattttt ttccaatcgc gtttcacgta ttgaatgaac
     4141 aatacgttcc aacgggcaaa tttttcattc attttctttt cctccgttcc gacaatcagc
     4201 cttcgtaatg acgcatgaat agatcttcaa gcgttggcgg tacagattcg atttttgtca
     4261 cacctaattt ggttgcctcg gtcagaatcg tattcatcgc ttcattgtca gcagaaaaag
     4321 ttgctttgcc gtctttttga acaaaatcat gcacgccaga gagcgtcgca agtttctcaa
     4381 tatcgccttc tgtcaccaat gtaactgttg agcgagtcaa atgacgcaat tcatctaatg
     4441 tacctgtttc aactacttct ccacgtcgaa tgattgctac tttatctgct aatcgttcaa
     4501 cttcacttaa aatatgtgaa gataatagaa tcgctttgcc atcatttttg attttttcta
     4561 cttcttcttg gaatactgct tccatcaatg gatctagtcc tgaagtcggt tcatctaaaa
     4621 tatacagatc agattcaact gaaagtgcag caatcaaacc gactttttga cgatttcctt
     4681 tagagtaacc tttggctttt ttctttggat caagttcaaa tcgtttgatt aaataatcgc
     4741 gctttgcttt gctcccgccg ccatgaagtt tgataaatag atcaatgatc tctccaccag
     4801 tcaggctgcc ccaaagagca acatctccag gaacatacga aattcgttta tggatttcta
     4861 gactatcttt ccaaacatct tttccgaata tttggacatc tccttcgtct ctgttgatga
     4921 ttcctagcag tgtacggatc gtcgttgact ttcctgctcc atttggtccg ataaaaccaa
     4981 caacttcacc ggcgtttact gtgaatgaga catctttcaa cgcctggaat ttaccaaatt
     5041 ttttttgcaa gccttgtact ggttctgttg caaagtttta aataaagaat aaaatccct
//
LOCUS       DAIGTA010000246         2211 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.146, whole genome shotgun sequence.
ACCESSION   DAIGTA010000246 DAIGTA010000000
VERSION     DAIGTA010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.146"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..115
                     /locus_tag="NOB43_003031"
     CDS             <1..115
                     /locus_tag="NOB43_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0983782.1"
                     /translation="LFDSRFKTLQQNPVNQICEITNVSRASLYRKLSEVNN"
     gene            329..1024
                     /gene="vanR"
                     /locus_tag="NOB43_003032"
     CDS             329..1024
                     /gene="vanR"
                     /locus_tag="NOB43_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI0983783.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1002..2156
                     /locus_tag="NOB43_003033"
     CDS             1002..2156
                     /locus_tag="NOB43_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI0983784.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          741 a          408 c          467 g          595 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccct gtaaatcaaa tttgtgaaat
       61 tactaatgta tctagggctt cattatacag gaaattatca gaagtgaata attagccatt
      121 ctgtattccg ctaatgggca atatttttaa agaagaaaag gaaactataa aatattaaca
      181 gcctcctagc gatgccgaaa agccctttga taaaaaaaga atcatcatct taagaaattc
      241 ttagtcattt attatgtaaa tgcttataaa ttcggcccta taatctgata aattattaag
      301 ggcaaactta tgtgaaaggg tgataactat gagcgataaa atacttattg tggatgatga
      361 acatgaaatt gccgatttgg ttgaattata cttaaaaaac gagaattata cggttttcaa
      421 atactatacc gccaaagaag cattggaatg tatagacaag tctgagattg accttgccat
      481 attggacatc atgcttcccg gcacaagcgg ccttactatc tgtcaaaaaa taagggacaa
      541 gcacacctat ccgattatca tgctgaccgg gaaagataca gaggtagata aaattacagg
      601 gttaacaatc ggcgcggatg attatataac gaagcccttt cgcccactgg agttaattgc
      661 tcgggtaaag gcccagttgc gccgatacaa aaaattcagt ggagtaaagg agcagaacga
      721 aaatgttatc gtccactccg gccttgtcat taatgttaac acccatgagt gttatctgaa
      781 cgagaagcag ttatccctta ctcccaccga gttttcaata ctgcgaatcc tctgtgaaaa
      841 caaggggaat gtggttagct ccgagctgct atttcatgag atatggggcg acgaatattt
      901 cagcaagagc aacaacacca tcaccgtgca tatccggcat ttgcgcgaaa aaatgaacga
      961 caccattgat aatccgaaat atataaaaac ggtatggggg gttggttata aaattgaaaa
     1021 ataaaaaaaa cgactattcc aaactagaac gaaaacttta catgtatatc gttgcaattg
     1081 ttgtggtagc aattgtattc gtgttgtata ttcgttcaat gatccgaggg aaacttgggg
     1141 attggatctt aagtattttg gaaaacaaat atgacttaaa tcacctggac gcgatgaaat
     1201 tatatcaata ttccatacgg aacaatatag atatctttat ttatgtggcg attgtcatta
     1261 gtattcttat tctatgtcgc gtcatgcttt caaaattcgc aaaatacttt gacgagataa
     1321 ataccggcat tgatgtactt attcagaacg aagataaaca aattgagctt tctgcggaaa
     1381 tggatgttat ggaacaaaag ctcaacacat taaaacggac tctggaaaag cgagagcagg
     1441 atgcaaagct ggccgaacaa agaaaaaatg acgttgttat gtacttggcg cacgatatta
     1501 aaacgcccct tacatccatt atcggttatt tgagcctgct tgacgaggct ccagacatgc
     1561 cggtagatca aaaggcaaag tatgtgcata tcacgttgga caaagcgtat cgactcgaac
     1621 agctaatcga cgagtttttt gagattacac ggtataacct acaaacgata acgctaacaa
     1681 aaacgcacat agacctatac tatatgctgg tgcagatgac cgatgaattt tatcctcagc
     1741 tttccgcaca tggaaaacag gcggttattc acgcccccga ggatctgacc gtgtccggcg
     1801 accctgataa actcgcgaga gtctttaaca acattttgaa aaacgccgct gcatacagtg
     1861 aggataacag catcattgac attaccgcgg gcctctccgg ggatgtggtg tcaatcgaat
     1921 tcaagaacac tggaagcatc ccaaaagata agctagctgc catatttgaa aagttctata
     1981 ggctggacaa tgctcgttct tccgatacgg gtggcgcggg acttggattg gcgattgcaa
     2041 aagaaattat tgttcagcat ggagggcaga tttacgcgga aagcaatgat aactatacga
     2101 cgtttagggt agagcttcca gcgatgccag acttggttga taaaaggagg tcctaagaga
     2161 tgtatataat tttggctctt tgtcaaatga tgttggtaaa gagaaatctt a
//
LOCUS       DAIGTA010000247         1743 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.158, whole genome shotgun sequence.
ACCESSION   DAIGTA010000247 DAIGTA010000000
VERSION     DAIGTA010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.158"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            13..378
                     /locus_tag="NOB43_003034"
     CDS             13..378
                     /locus_tag="NOB43_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0983785.1"
                     /translation="MVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPDGKT
                     MFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEKLGG
                     KNDYKDEIVYVYDYEKGDK"
     gene            379..>1743
                     /gene="aph(2'')-I"
                     /locus_tag="NOB43_003035"
     CDS             379..>1743
                     /gene="aph(2'')-I"
                     /locus_tag="NOB43_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HCI0983786.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVY"
BASE COUNT          718 a          133 c          298 g          594 t
ORIGIN      
        1 attgatgata atatggtttt tgatattgat aatttaaaag gatttcttaa tgataccagt
       61 tcatttgggt ttatagctaa agaaaataat aaaattatag gatttgcata ttgctataca
      121 cttttaagac ctgatggaaa aacaatgttt tatttacact caataggaat gttacctaac
      181 tatcaagaca aaggttatgg ttcaaaatta ttatctttta ttaaggaata ttctaaagag
      241 attggttgtt ctgaaatgtt tttaataact gataaaggta atcctagagc ttgccatgta
      301 tatgaaaaat taggtggtaa aaatgattat aaagatgaaa tagtatatgt atatgattat
      361 gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa tatgtataag aactttaata
      421 gatgatgatt ttcctttgat gttaaaatgg ttaactgatg aaagagtatt agaattttat
      481 gatggtagag ataaaaaata tacattagaa tcattaaaaa aacattatac agagccttgg
      541 gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg atatggacaa
      601 atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac tgatgagata
      661 gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg aattggtaca
      721 agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa tgcagttatt
      781 ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc tggttttaga
      841 attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga ttgttattta
      901 atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata tttaattgag
      961 cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg ttatgatagt
     1021 gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac taataagaaa
     1081 aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt agaaactaat
     1141 gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat actaggttat
     1201 aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc agaagaagaa
     1261 caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg tttagattat
     1321 acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga gtatatattg
     1381 ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat agaaagtttt
     1441 atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg ccataatgat
     1501 tttagttgta atcatctatt gttagatggc aataatagat taactggaat aattgatttt
     1561 ggagattctg gaattataga tgaatattgt gattttatat acttacttga agatagtgaa
     1621 gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa tatagatatt
     1681 gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga aactattgtt
     1741 tat
//
LOCUS       DAIGTA010000248         1743 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.159, whole genome shotgun sequence.
ACCESSION   DAIGTA010000248 DAIGTA010000000
VERSION     DAIGTA010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.159"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            13..378
                     /locus_tag="NOB43_003036"
     CDS             13..378
                     /locus_tag="NOB43_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0983787.1"
                     /translation="MVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPDGKT
                     MFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEKLGG
                     KNDYKDEIVYVYDYEKGDK"
     gene            379..>1743
                     /gene="aph(2'')-I"
                     /locus_tag="NOB43_003037"
     CDS             379..>1743
                     /gene="aph(2'')-I"
                     /locus_tag="NOB43_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HCI0983788.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVY"
BASE COUNT          717 a          133 c          299 g          594 t
ORIGIN      
        1 attgatgata atatggtttt tgatattgat aatttaaaag gatttcttaa tgataccagt
       61 tcatttgggt ttatagctaa agaaaataat aaaattatag gatttgcata ttgctataca
      121 cttttaagac ctgatggaaa aacaatgttt tatttacact caataggaat gttacctaac
      181 tatcaagaca aaggttatgg ttcaaaatta ttatctttta ttaaggaata ttctaaagag
      241 attggttgtt ctgaaatgtt tttaataact gataaaggta atcctagagc ttgccatgta
      301 tatgaaaaat taggtggtaa aaatgattat aaagatgaaa tagtatatgt atatgattat
      361 gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa tatgtataag aactttaata
      421 gatgatgatt ttcctttgat gttaaaatgg ttaactgatg aaagagtatt agaattttat
      481 ggtggtagag ataaaaaata tacattagaa tcattaaaaa aacattatac agagccttgg
      541 gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg atatggacaa
      601 atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac tgatgagata
      661 gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg aattggtaca
      721 agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa tgcagttatt
      781 ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc tggttttaga
      841 attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga ttgttattta
      901 atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata tttaattgag
      961 cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg ttatgatagt
     1021 gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac taataagaaa
     1081 aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt agaaactaat
     1141 gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat actaggttat
     1201 aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc agaagaagaa
     1261 caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg tttagattat
     1321 acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga gtatatattg
     1381 ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat agaaagtttt
     1441 atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg ccataatgat
     1501 tttagttgta atcatctatt gttagatggc aataatagat taactggaat aattgatttt
     1561 ggagattctg gaattataga tgaatattgt gattttatat acttacttga agatagtgaa
     1621 gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa tatagatatt
     1681 gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga aactattgtt
     1741 tat
//
LOCUS       DAIGTA010000249         1309 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.170, whole genome shotgun sequence.
ACCESSION   DAIGTA010000249 DAIGTA010000000
VERSION     DAIGTA010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.170"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            <1..>1309
                     /locus_tag="NOB43_003038"
     CDS             <1..>1309
                     /locus_tag="NOB43_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HCI0983789.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          553 a          101 c          224 g          431 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagatt
//
LOCUS       DAIGTA010000250          870 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1233-ENTFAE
            SAMN29456783-rid14857653.guided.188, whole genome shotgun sequence.
ACCESSION   DAIGTA010000250 DAIGTA010000000
VERSION     DAIGTA010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456783
            Sequence Read Archive: SRR19916773
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361048.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361048.1
            Genome Coverage       :: 134x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:20:28
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,039
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,875
            CDSs (with protein)               :: 2,875
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 44 of 101
            Pseudo Genes (incomplete)         :: 44 of 101
            Pseudo Genes (internal stop)      :: 32 of 101
            Pseudo Genes (multiple problems)  :: 16 of 101
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456783-rid14857653.guided.188"
                     /strain="microbial"
                     /isolate="V1233-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-03"
     gene            155..703
                     /gene="aac(6')"
                     /locus_tag="NOB43_003039"
     CDS             155..703
                     /gene="aac(6')"
                     /locus_tag="NOB43_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI0983790.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          311 a          127 c          192 g          240 t
ORIGIN      
        1 tgaataaagt gtttctgtat aattttttta ttttataagt aagataaata atgaaagaat
       61 agagatactg attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga
      121 ctgttagaat aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa
      181 taatccagta ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata
      241 tggagacagc tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc
      301 agcggtagac caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac
      361 aggttgggaa ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac
      421 tcgattagtc aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt
      481 aggtacggat gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac
      541 atttgataaa gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa
      601 attaggttat aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat
      661 ttggatggca aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac
      721 agaagtaatc agcttcaaga aataagaagg aatttacgaa aattacttct tgaatttttg
      781 tgaaattcca acttatttcc gaagaagcta cttttggaac accgtgtacc agaggttgtg
      841 aaaaagtcgc ttagtttcga gtagtaagaa
//
